Sample records for national genetic resources

  1. Drosophila Genetic Resource and Stock Center; The National BioResource Project.

    PubMed

    Yamamoto, Masa-Toshi

    2010-01-01

    The fruit fly, Drosophila melanogaster, is not categorized as a laboratory animal, but it is recognised as one of the most important model organisms for basic biology, life science, and biomedical research. This tiny fly continues to occupy a core place in genetics and genomic approaches to studies of biology and medicine. The basic principles of genetics, including the variations of phenotypes, mutations, genetic linkage, meiotic chromosome segregation, chromosome aberrations, recombination, and precise mapping of genes by genetic as well as cytological means, were all derived from studies of Drosophila. Recombinant DNA technology was developed in the 1970s and Drosophila DNA was the first among multicellular organisms to be cloned. It provided a detailed characterization of genes in combination of classical cytogenetic data. Drosophila thus became the pioneering model organism for various fields of life science research into multicellular organisms. Here, I briefly describe the history of Drosophila research and provide a few examples of the application of the abundant genetic resources of Drosophila to basic biology and medical investigations. A Japanese national project, the National BioResource Project (NBRP) for collection, maintainance, and provision of Drosophila resources, that is well known and admired by researchers in other countries as an important project, is also briefly described.

  2. Options and legal requirements for national and regional animal genetic resources collections

    USDA-ARS?s Scientific Manuscript database

    The contraction of animal genetic resources on a global scale has motivated countries to establish gene banks as a mechanism to conserve national resources. Gene banks should establish a set of policies that insure they are complying with national laws. The two primary areas of consideration are ho...

  3. National Newborn Screening and Genetics Resource Center

    MedlinePlus

    ... GENERAL INFORMATION Conditions Screened by US Programs General Resources Genetics Birth Defects Hearing Screening FOR PROFESSIONALS ACT Sheets(ACMG) General Resources Newborn Screening Genetics Birth Defects FOR FAMILIES FAQs ...

  4. 76 FR 35396 - Notice of Intent To Reestablish the National Genetic Resources Advisory Council, and Request for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-17

    ... DEPARTMENT OF AGRICULTURE Agricultural Research Service Notice of Intent To Reestablish the National Genetic Resources Advisory Council, and Request for Nominations AGENCY: Agricultural Research... intent to reestablish the National Genetic Resources Advisory Council. The notice was published in the...

  5. Cotton genetic resources and crop vulnerability

    USDA-ARS?s Scientific Manuscript database

    A report on the genetic vulnerability of cotton was provided to the National Genetic Resources Advisory Council. The report discussed crop vulnerabilities associated with emerging diseases, emerging pests, and a narrowing genetic base. To address these crop vulnerabilities, the report discussed the ...

  6. Prioritization of Malus accessions for collection cryopreservation at the USDA-ARS National Center for Genetic Resources Preservation

    USDA-ARS?s Scientific Manuscript database

    The USDA-ARS National Plant Germplasm System maintains a grafted collection of apple accessions representing 49 taxa in Geneva, NY. Dormant buds of many of these accessions have been routinely cryopreserved at the USDA-ARS National Center for Genetic Resources Preservation (NCGRP) in Fort Collins, C...

  7. The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chesler, Elissa J; Branstetter, Lisa R; Churchill, Gary A

    2008-01-01

    Complex traits and disease co-morbidity in humans and in model organisms are the result of naturally occurring polymorphisms that interact with each other and with the environment. To ensure the availability of the resources needed to investigate biomolecular networks and ultimately systems level phenotypes, we have initiated breeding of a new genetic reference population of mice, the Collaborative Cross. This population has been designed to optimally support systems genetics analysis. Its novel and important features include high levels of genetic diversity, a large population size to ensure sufficient power in high-dimensional studies, and high mapping precision through accumulation of independentmore » recombination events. Implementation of the Collaborative Cross has been in progress at the Oak Ridge National Laboratory (ORNL) since May 2005. This is achieved through a software assisted breeding program with fully traceable lineages, performed in a uniform environment. Currently, there are 650 lines in production with almost 200 lines over seven generations of inbreeding. Retired breeders enter a high-throughput phenotyping protocol and DNA samples are banked for analysis of recombination history, allele loss, and population structure. Herein we present a progress report of the Collaborative Cross breeding program at ORNL and a description of the kinds of investigations that this resource will support.« less

  8. Sharing the benefits of genetic resources: from biodiversity to human genetics.

    PubMed

    Schroeder, Doris; Lasén-Díaz, Carolina

    2006-12-01

    Benefit sharing aims to achieve an equitable exchange between the granting of access to a genetic resource and the provision of compensation. The Convention on Biological Diversity (CBD), adopted at the 1992 Earth Summit in Rio de Janeiro, is the only international legal instrument setting out obligations for sharing the benefits derived from the use of biodiversity. The CBD excludes human genetic resources from its scope, however, this article considers whether it should be expanded to include those resources, so as to enable research subjects to claim a share of the benefits to be negotiated on a case-by-case basis. Our conclusion on this question is: 'No, the CBD should not be expanded to include human genetic resources.' There are essential differences between human and non-human genetic resources, and, in the context of research on humans, an essentially fair exchange model is already available between the health care industry and research subjects. Those who contribute to research should receive benefits in the form of accessible new health care products and services, suitable for local health needs and linked to economic prosperity (e.g. jobs). When this exchange model does not apply, as is often the case in developing countries, individually negotiated benefit sharing agreements between researchers and research subjects should not be used as 'window dressing'. Instead, national governments should focus their finances on the best economic investment they could make; the investment in population health and health research as outlined by the World Health Organization's Commission on Macroeconomics and Health; whilst international barriers to such spending need to be removed.

  9. A new definition of Genetic Counseling: National Society of Genetic Counselors' Task Force report.

    PubMed

    Resta, Robert; Biesecker, Barbara Bowles; Bennett, Robin L; Blum, Sandra; Hahn, Susan Estabrooks; Strecker, Michelle N; Williams, Janet L

    2006-04-01

    The Genetic Counseling Definition Task Force of the National Society of Genetic Counselors (NSGC) developed the following definition of genetic counseling that was approved by the NSGC Board of Directors: Genetic counseling is the process of helping people understand and adapt to the medical, psychological and familial implications of genetic contributions to disease. This process integrates the following: Interpretation of family and medical histories to assess the chance of disease occurrence or recurrence. Education about inheritance, testing, management, prevention, resources and research. Counseling to promote informed choices and adaptation to the risk or condition. The definition was approved after a peer review process with input from the NSGC membership, genetic professional organizations, the NSGC legal counsel, and leaders of several national genetic advocacy groups.

  10. Deep-sea genetic resources: New frontiers for science and stewardship in areas beyond national jurisdiction

    NASA Astrophysics Data System (ADS)

    Harden-Davies, Harriet

    2017-03-01

    The deep-sea is a large source of marine genetic resources (MGR), which have many potential uses and are a growing area of research. Much of the deep-sea lies in areas beyond national jurisdiction (ABNJ), including 65% of the global ocean. MGR in ABNJ occupy a significant gap in the international legal framework. Access and benefit sharing of MGR is a key issue in the development of a new international legally-binding instrument under the United Nations Convention on the Law of the Sea (UNCLOS) for the conservation and sustainable use of marine biological diversity in ABNJ. This paper examines how this is relevant to deep-sea scientific research and identifies emerging challenges and opportunities. There is no internationally agreed definition of MGR, however, deep-sea genetic resources could incorporate any biological material including genes, proteins and natural products. Deep-sea scientific research is the key actor accessing MGR in ABNJ and sharing benefits such as data, samples and knowledge. UNCLOS provides the international legal framework for marine scientific research, international science cooperation, capacity building and marine technology transfer. Enhanced implementation could support access and benefit sharing of MGR in ABNJ. Deep-sea scientific researchers could play an important role in informing practical new governance solutions for access and benefit sharing of MGR that promote scientific research in ABNJ and support deep-sea stewardship. Advancing knowledge of deep-sea biodiversity in ABNJ, enhancing open-access to data and samples, standardisation and international marine science cooperation are significant potential opportunity areas.

  11. Maize Genetic Resources Collections – Utilizing a Treasure Trove

    USDA-ARS?s Scientific Manuscript database

    The maize genetic resource collection managed by the USDA-ARS's National Plant Germplasm System is heavily utilized by researchers and educators. A collection of landraces, inbred lines from public and private sector sources, synthetics and key populations, it serves both as a living snapshot of th...

  12. Genetic Simulation Resources: a website for the registration and discovery of genetic data simulators

    PubMed Central

    Peng, Bo; Chen, Huann-Sheng; Mechanic, Leah E.; Racine, Ben; Clarke, John; Clarke, Lauren; Gillanders, Elizabeth; Feuer, Eric J.

    2013-01-01

    Summary: Many simulation methods and programs have been developed to simulate genetic data of the human genome. These data have been widely used, for example, to predict properties of populations retrospectively or prospectively according to mathematically intractable genetic models, and to assist the validation, statistical inference and power analysis of a variety of statistical models. However, owing to the differences in type of genetic data of interest, simulation methods, evolutionary features, input and output formats, terminologies and assumptions for different applications, choosing the right tool for a particular study can be a resource-intensive process that usually involves searching, downloading and testing many different simulation programs. Genetic Simulation Resources (GSR) is a website provided by the National Cancer Institute (NCI) that aims to help researchers compare and choose the appropriate simulation tools for their studies. This website allows authors of simulation software to register their applications and describe them with well-defined attributes, thus allowing site users to search and compare simulators according to specified features. Availability: http://popmodels.cancercontrol.cancer.gov/gsr. Contact: gsr@mail.nih.gov PMID:23435068

  13. Redesigning the exploitation of wheat genetic resources.

    PubMed

    Longin, C Friedrich H; Reif, Jochen C

    2014-10-01

    More than half a million wheat genetic resources are resting in gene banks worldwide. Unlocking their hidden favorable genetic diversity for breeding is pivotal for enhancing grain yield potential, and averting future food shortages. Here, we propose exploiting recent advances in hybrid wheat technology to uncover the masked breeding values of wheat genetic resources. The gathered phenotypic information will enable a targeted choice of accessions with high value for pre-breeding among this plethora of genetic resources. We intend to provoke a paradigm shift in pre-breeding strategies for grain yield, moving away from allele mining toward genome-wide selection to bridge the yield gap between genetic resources and elite breeding pools. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. Resources for Systems Genetics.

    PubMed

    Williams, Robert W; Williams, Evan G

    2017-01-01

    A key characteristic of systems genetics is its reliance on populations that vary to a greater or lesser degree in genetic complexity-from highly admixed populations such as the Collaborative Cross and Diversity Outcross to relatively simple crosses such as sets of consomic strains and reduced complexity crosses. This protocol is intended to help investigators make more informed decisions about choices of resources given different types of questions. We consider factors such as costs, availability, and ease of breeding for common scenarios. In general, we recommend using complementary resources and minimizing depth of resampling of any given genome or strain.

  15. RNGR: A national resource for reforestation, restoration, and nursery professionals

    Treesearch

    Diane L. Haase; Jeremiah R. Pinto; R. Kasten Dumroese; George Hernandez; Bob Karrfalt; Ron Overton

    2011-01-01

    The Forest Service developed the national Reforestation, Nurseries, and Genetics Resources (RNGR) program to provide expert support to State, industrial, and private forest and conservation nurseries throughout the country. The RNGR program includes technical assistance to nurseries, research projects (to address seedling and field issues), and Internet sites. RNGR...

  16. Establishing sugarcane (Saccharum spp.) genetic resources for in vitro storage and cryopreservation

    USDA-ARS?s Scientific Manuscript database

    Sugarcane (Saccharum spp.) is used to produce sugar, a variety of alcoholic beverages, bagasse and industrial ethanol utilized in making fuel. In production fields, sugarcane is propagated vegetatively and currently, the crop’s genetic resources are also preserved as field plantings. The National Pl...

  17. Gene co-ops and the biotrade: translating genetic resource rights into sustainable development.

    PubMed

    Reid, W V

    1996-04-01

    The 1992 Convention on Biological Diversity marks a basic change in the international status of genetic resources. Prior to the Convention, these resources were considered to be the "heritage of mankind.' Although the intent of this open access regime was to ensure the widespread availability of genetic resources for agriculture and industry, commercial use of the resources provided no additional economic incentive for conservation by source countries. The Biodiversity Convention corrects this policy failure by establishing that states have sovereign rights over their genetic resources, thereby enabling market incentives to complement various multilateral mechanisms that might directly fund biodiversity conservation. A number of obstacles face countries that are translating this broad right to regulate access into specific policies, laws, and regulations designed to meet conservation and development objectives. A review of these obstacles and of trends in technological development suggest that nations and developing country institutions should take a set of actions to develop access legislation and Material Transfer Agreements, establish biodiversity "cooperatives' and intermediary institutions to facilitate information exchange, develop minimum standards for access legislation, and require that prior informed consent of local communities be obtained by all biodiversity collectors.

  18. U.S. Sorghum genetic resources collection: 15 years of progress (2001-2016)

    USDA-ARS?s Scientific Manuscript database

    The U.S. sorghum genetic resources collection at Griffin, GA, is one of the largest collections in the National Plant Germplasm System. In 2001, improved maintenance was greatly needed as accessions weren’t regenerated routinely, viability tests weren’t conducted, and most seed was stored in 4C inst...

  19. Isozymes and the genetic resources of forest trees

    Treesearch

    A. H. D. Brown; G. F. Moran

    1981-01-01

    Genetic data are an essential prerequisite for analysing the genetic structure of tree populations. The isozyme technique is the best currently available method for obtaining such data. Despite several shortcomings, isozyme data directly evaluate the genetic resources of forest trees, and can thus be used to monitor and manipulate these resources. For example,...

  20. Molecular fingerprinting of cacao (Theobroma cacao L.) genetic resources in the Dominican Republic

    USDA-ARS?s Scientific Manuscript database

    Cacao (Theobroma cacao L.) is a significant agricultural commodity in the Dominican Republic ranking 11th in the world and number one in organic cacao exports. Dominican cacao genetic resources are maintained, propagated and distributed nationally out of the IDIAF’s Mata Larga research stations. T...

  1. Cryopreservation for preservation of potato genetic resources

    PubMed Central

    Niino, Takao; Arizaga, Miriam Valle

    2015-01-01

    Cryopreservation is becoming a very important tool for the long-term storage of plant genetic resources and efficient cryopreservation protocols have been developed for a large number of plant species. Practical procedures, developed using in vitro tissue culture, can be a simple and reliable preservation option of potato genetic resources rather than maintaining by vegetative propagation in genebanks due their allogamous nature. Cryopreserved materials insure a long-term backup of field collections against loss of plant germplasm. Occurrence of genetic variation, in tissue culture cells during prolonged subcultures, can be avoided with suitable cryopreservation protocols that provide high regrowth, leading and facilitating a systematic and strategic cryo-banking of plant genetic resources. Cryopreservation protocols for potato reviewed here, can efficiently complement field and in vitro conservation, providing for preservation of genotypes difficult to preserve by other methods, wild types and other species decided as priority collections. PMID:25931979

  2. The U.S. Forest Service National Seed Laboratory and Fraxinus ex situ genetic conservation

    Treesearch

    Robert P. Karrfalt

    2010-01-01

    The U.S. Forest Service's National Seed Laboratory (NSL) has as part of its mission the conservation of genetic resources for the Forest Service and Forest Service cooperators through long-term seed storage. The Forest Service recognizes ash as one of four priority species for genetic conservation. The NSL is in charge of the Forest Service ash preservation plan...

  3. Genetic diversity among wheat accessions from the USDA National Small Grains Collection

    USDA-ARS?s Scientific Manuscript database

    Accessions of Triticum aestivum subsp. aestivum from the USDA-ARS National Small Grains Collection (NSGC) are a resource for wheat scientists worldwide. The genetic diversity of the wheat core subset, representing approximately 10% of the collection’s 42138 T. aestivum accessions, was examined using...

  4. Harvesting Legume Genomes: Plant Genetic Resources

    USDA-ARS?s Scientific Manuscript database

    Genomics and high through-put phenotyping are ushering in a new era of accessing genetic diversity held in plant genetic resources, the cornerstone of both traditional and genomics-assisted breeding efforts of food legume crops. Acknowledged or not, yield plateaus must be broken given the daunting ...

  5. Corporate control and global governance of marine genetic resources

    PubMed Central

    Österblom, Henrik

    2018-01-01

    Who owns ocean biodiversity? This is an increasingly relevant question, given the legal uncertainties associated with the use of genetic resources from areas beyond national jurisdiction, which cover half of the Earth’s surface. We accessed 38 million records of genetic sequences associated with patents and created a database of 12,998 sequences extracted from 862 marine species. We identified >1600 sequences from 91 species associated with deep-sea and hydrothermal vent systems, reflecting commercial interest in organisms from remote ocean areas, as well as a capacity to collect and use the genes of such species. A single corporation registered 47% of all marine sequences included in gene patents, exceeding the combined share of 220 other companies (37%). Universities and their commercialization partners registered 12%. Actors located or headquartered in 10 countries registered 98% of all patent sequences, and 165 countries were unrepresented. Our findings highlight the importance of inclusive participation by all states in international negotiations and the urgency of clarifying the legal regime around access and benefit sharing of marine genetic resources. We identify a need for greater transparency regarding species provenance, transfer of patent ownership, and activities of corporations with a disproportionate influence over the patenting of marine biodiversity. We suggest that identifying these key actors is a critical step toward encouraging innovation, fostering greater equity, and promoting better ocean stewardship. PMID:29881777

  6. Potential International Approaches to Ownership/Control of Human Genetic Resources.

    PubMed

    Rhodes, Catherine

    2016-09-01

    In its governance activities for genetic resources, the international community has adopted various approaches to their ownership, including: free access; common heritage of mankind; intellectual property rights; and state sovereign rights. They have also created systems which combine elements of these approaches. While governance of plant and animal genetic resources is well-established internationally, there has not yet been a clear approach selected for human genetic resources. Based on assessment of the goals which international governance of human genetic resources ought to serve, and the implications for how they will be accessed and utilised, it is argued that common heritage of mankind will be the most appropriate approach to adopt to their ownership/control. It does this with the aim of stimulating discussion in this area and providing a starting point for deeper consideration of how a common heritage of mankind, or similar, regime for human genetic resources would function and be implemented.

  7. Database resources of the National Center for Biotechnology Information

    PubMed Central

    2015-01-01

    The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank® nucleic acid sequence database and the PubMed database of citations and abstracts for published life science journals. Additional NCBI resources focus on literature (Bookshelf, PubMed Central (PMC) and PubReader); medical genetics (ClinVar, dbMHC, the Genetic Testing Registry, HIV-1/Human Protein Interaction Database and MedGen); genes and genomics (BioProject, BioSample, dbSNP, dbVar, Epigenomics, Gene, Gene Expression Omnibus (GEO), Genome, HomoloGene, the Map Viewer, Nucleotide, PopSet, Probe, RefSeq, Sequence Read Archive, the Taxonomy Browser, Trace Archive and UniGene); and proteins and chemicals (Biosystems, COBALT, the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART), the Molecular Modeling Database (MMDB), Protein Clusters, Protein and the PubChem suite of small molecule databases). The Entrez system provides search and retrieval operations for many of these databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of these resources can be accessed through the NCBI home page at http://www.ncbi.nlm.nih.gov. PMID:25398906

  8. National Aquatic Resource Surveys

    EPA Pesticide Factsheets

    EPA reports information on the condition of our nation's waters using probabilistic surveys. The National Aquatic Resource Surveys assess the status of and changes in water quality of the nation's coastal waters, lakes, rivers and streams, and wetlands.

  9. Studies on Monitoring and Tracking Genetic Resources: An Executive Summary

    PubMed Central

    Garrity, George M.; Thompson, Lorraine M.; Ussery, David W.; Paskin, Norman; Baker, Dwight; Desmeth, Philippe; Schindel, D.E.; Ong, P.S.

    2009-01-01

    The principles underlying fair and equitable sharing of benefits derived from the utilization of genetic resources are set out in Article 15 of the UN Convention on Biological Diversity, which stipulate that access to genetic resources is subject to the prior informed consent of the country where such resources are located and to mutually agreed terms regarding the sharing of benefits that could be derived from such access. One issue of particular concern for provider countries is how to monitor and track genetic resources once they have left the provider country and enter into use in a variety of forms. This report was commissioned to provide a detailed review of advances in DNA sequencing technologies, as those methods apply to identification of genetic resources, and the use of globally unique persistent identifiers for persistently linking to data and other forms of digital documentation that is linked to individual genetic resources. While the report was written for an audience with a mixture of technical, legal, and policy backgrounds it is relevant to the genomics community as it is an example of downstream application of genomics information. PMID:21304641

  10. Cryopreservation of eucalyptus genetic resources

    USDA-ARS?s Scientific Manuscript database

    The long-term preservation of forest genetic resources is a vital part of preserving our forest crops for future generations. Unfortunately there are few genebanks dedicated to forest trees and very few methods aside from field plantings of germplasm collections of elite clonal individuals. The use ...

  11. Expanding maize genetic resources with predomestication alleles: maize-teosinte introgression populations

    USDA-ARS?s Scientific Manuscript database

    Teosinte (Zea mays ssp. parviglumis) has greater genetic diversity than maize inbreds and landraces (Z. mays ssp. mays). There are, however, limited genetic resources to efficiently evaluate and tap this diversity. To broaden resources for genetic diversity studies in maize, we developed and evaluat...

  12. Poultry genetic resource conservation using primordial germ cells

    PubMed Central

    NAKAMURA, Yoshiaki

    2016-01-01

    The majority of poultry genetic resources are maintained in situ in living populations. However, in situ conservation of poultry genetic resources always carries the risk of loss owing to pathogen outbreaks, genetic problems, breeding cessation, or natural disasters. Cryobanking of germplasm in birds has been limited to the use of semen, preventing conservation of the W chromosome and mitochondrial DNA. A further challenge is posed by the structure of avian eggs, which restricts the cryopreservation of ova and fertilized embryos, a technique widely used for mammalian species. By using a unique biological property and accessibility of avian primordial germ cells (PGCs), precursor cells for gametes, which temporally circulate in the vasculature during early development, an avian PGC transplantation technique has been established. To date, several techniques for PGC manipulation including purification, cryopreservation, depletion, and long-term culture have been developed in chickens. PGC transplantation combined with recent advanced PGC manipulation techniques have enabled ex situ conservation of poultry genetic resources in their complete form. Here, the updated technologies for avian PGC manipulation are introduced, and then the concept of a poultry PGC-bank is proposed by considering the biological properties of avian PGCs. PMID:27210834

  13. Molecular genetics research in ADHD: ethical considerations concerning patients' benefit and resource allocation.

    PubMed

    Rothenberger, Lillian Geza

    2012-12-01

    Immense resource allocations have led to great data output in genetic research. Concerning ADHD resources spent on genetic research are less than those spent on clinical research. But there are successful efforts made to increase support for molecular genetics research in ADHD. Concerning genetics no evidence based conclusive results have significant impact on prevention, diagnosis or treatment yet. With regard to ethical aspects like the patients' benefit and limited resources the question arises if it is indicated to think about a new balance of resource allocation between molecular genetics and non-genetics research in ADHD. An ethical reflection was performed focusing on recent genetic studies and reviews based on a selective literature search. There are plausible reasons why genetic research results in ADHD are somehow disappointing for clinical practice so far. Researchers try to overcome these gaps systematically, without knowing what the potential future benefits for the patients might be. Non-genetic diagnostic/therapeutic research may lead to clinically relevant findings within a shorter period of time. On the other hand, non-genetic research in ADHD may be nurtured by genetic approaches. But, with the latter there exist significant risks of harm like stigmatization and concerns regarding data protection. Isolated speeding up resources of genetic research in ADHD seems questionable from an ethical point of view. There is a need to find a new balance of resource allocation between genetic and non-genetic research in ADHD, probably by integrating genetics more systematically into clinical research. A transdisciplinary debate is recommended. Copyright © 2012 Wiley Periodicals, Inc.

  14. 2018 National Resources Inventory (NRI) Rangeland Resource Assessment

    USDA-ARS?s Scientific Manuscript database

    This report presents summary results from National Resources Inventory (NRI) on-site data collected on non-Federal rangelands. The survey is conducted by the U.S. Department of Agriculture’s Natural Resources Conservation Service (NRCS) as a part of the NRI survey program. The findings reported here...

  15. Database resources of the National Center for Biotechnology Information.

    PubMed

    2015-01-01

    The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank(®) nucleic acid sequence database and the PubMed database of citations and abstracts for published life science journals. Additional NCBI resources focus on literature (Bookshelf, PubMed Central (PMC) and PubReader); medical genetics (ClinVar, dbMHC, the Genetic Testing Registry, HIV-1/Human Protein Interaction Database and MedGen); genes and genomics (BioProject, BioSample, dbSNP, dbVar, Epigenomics, Gene, Gene Expression Omnibus (GEO), Genome, HomoloGene, the Map Viewer, Nucleotide, PopSet, Probe, RefSeq, Sequence Read Archive, the Taxonomy Browser, Trace Archive and UniGene); and proteins and chemicals (Biosystems, COBALT, the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART), the Molecular Modeling Database (MMDB), Protein Clusters, Protein and the PubChem suite of small molecule databases). The Entrez system provides search and retrieval operations for many of these databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of these resources can be accessed through the NCBI home page at http://www.ncbi.nlm.nih.gov. Published by Oxford University Press on behalf of Nucleic Acids Research 2014. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  16. Selective breeding in fish and conservation of genetic resources for aquaculture.

    PubMed

    Lind, C E; Ponzoni, R W; Nguyen, N H; Khaw, H L

    2012-08-01

    To satisfy increasing demands for fish as food, progress must occur towards greater aquaculture productivity whilst retaining the wild and farmed genetic resources that underpin global fish production. We review the main selection methods that have been developed for genetic improvement in aquaculture, and discuss their virtues and shortcomings. Examples of the application of mass, cohort, within family, and combined between-family and within-family selection are given. In addition, we review the manner in which fish genetic resources can be lost at the intra-specific, species and ecosystem levels and discuss options to best prevent this. We illustrate that fundamental principles of genetic management are common in the implementation of both selective breeding and conservation programmes, and should be emphasized in capacity development efforts. We highlight the value of applied genetics approaches for increasing aquaculture productivity and the conservation of fish genetic resources. © 2012 Blackwell Verlag GmbH.

  17. Biotechnologies for the management of genetic resources for food and agriculture.

    PubMed

    Lidder, Preetmoninder; Sonnino, Andrea

    2012-01-01

    In recent years, the land area under agriculture has declined as also has the rate of growth in agricultural productivity while the demand for food continues to escalate. The world population now stands at 7 billion and is expected to reach 9 billion in 2045. A broad range of agricultural genetic diversity needs to be available and utilized in order to feed this growing population. Climate change is an added threat to biodiversity that will significantly impact genetic resources for food and agriculture (GRFA) and food production. There is no simple, all-encompassing solution to the challenges of increasing productivity while conserving genetic diversity. Sustainable management of GRFA requires a multipronged approach, and as outlined in the paper, biotechnologies can provide powerful tools for the management of GRFA. These tools vary in complexity from those that are relatively simple to those that are more sophisticated. Further, advances in biotechnologies are occurring at a rapid pace and provide novel opportunities for more effective and efficient management of GRFA. Biotechnology applications must be integrated with ongoing conventional breeding and development programs in order to succeed. Additionally, the generation, adaptation, and adoption of biotechnologies require a consistent level of financial and human resources and appropriate policies need to be in place. These issues were also recognized by Member States at the FAO international technical conference on Agricultural Biotechnologies for Developing Countries (ABDC-10), which took place in March 2010 in Mexico. At the end of the conference, the Member States reached a number of key conclusions, agreeing, inter alia, that developing countries should significantly increase sustained investments in capacity building and the development and use of biotechnologies to maintain the natural resource base; that effective and enabling national biotechnology policies and science-based regulatory frameworks can

  18. 75 FR 69619 - Chippewa National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-15

    ... DEPARTMENT OF AGRICULTURE Forest Service Chippewa National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Chippewa National Forest Resource... information on national forest projects and processes to the Chippewa National Forest Resource Advisory...

  19. Genetic Distinctiveness of Rye In situ Accessions from Portugal Unveils a New Hotspot of Unexplored Genetic Resources

    PubMed Central

    Monteiro, Filipa; Vidigal, Patrícia; Barros, André B.; Monteiro, Ana; Oliveira, Hugo R.; Viegas, Wanda

    2016-01-01

    Rye (Secale cereale L.) is a cereal crop of major importance in many parts of Europe and rye breeders are presently very concerned with the restrict pool of rye genetic resources available. Such narrowing of rye genetic diversity results from the presence of “Petkus” pool in most modern rye varieties as well as “Petkus” × “Carsten” heterotic pool in hybrid rye breeding programs. Previous studies on rye's genetic diversity revealed moreover a common genetic background on landraces (ex situ) and cultivars, regardless of breeding level or geographical origin. Thus evaluation of in situ populations is of utmost importance to unveil “on farm” diversity, which is largely undervalued. Here, we perform the first comprehensive assessment of rye's genetic diversity and population structuring using cultivars, ex situ landraces along a comprehensive sampling of in situ accessions from Portugal, through a molecular-directed analysis using SSRs markers. Rye genetic diversity and population structure analysis does not present any geographical trend but disclosed marked differences between genetic backgrounds of in situ accessions and those of cultivars/ex situ collections. Such genetic distinctiveness of in situ accessions highlights their unexplored potential as new genetic resources, which can be used to boost rye breeding strategies and the production of new varieties. Overall, our study successfully demonstrates the high prospective impact of comparing genetic diversity and structure of cultivars, ex situ, and in situ samples in ascertaining the status of plant genetic resources (PGR). PMID:27630658

  20. Genetic Resources in the "Calabaza Pipiana" Squash (Cucurbita argyrosperma) in Mexico: Genetic Diversity, Genetic Differentiation and Distribution Models.

    PubMed

    Sánchez-de la Vega, Guillermo; Castellanos-Morales, Gabriela; Gámez, Niza; Hernández-Rosales, Helena S; Vázquez-Lobo, Alejandra; Aguirre-Planter, Erika; Jaramillo-Correa, Juan P; Montes-Hernández, Salvador; Lira-Saade, Rafael; Eguiarte, Luis E

    2018-01-01

    Analyses of genetic variation allow understanding the origin, diversification and genetic resources of cultivated plants. Domesticated taxa and their wild relatives are ideal systems for studying genetic processes of plant domestication and their joint is important to evaluate the distribution of their genetic resources. Such is the case of the domesticated subspecies C. argyrosperma ssp. argyrosperma , known in Mexico as calabaza pipiana , and its wild relative C. argyrosperma ssp. sororia . The main aim of this study was to use molecular data (microsatellites) to assess the levels of genetic variation and genetic differentiation within and among populations of domesticated argyrosperma across its distribution in Mexico in comparison to its wild relative, sororia , and to identify environmental suitability in previously proposed centers of domestication. We analyzed nine unlinked nuclear microsatellite loci to assess levels of diversity and distribution of genetic variation within and among populations in 440 individuals from 19 populations of cultivated landraces of argyrosperma and from six wild populations of sororia , in order to conduct a first systematic analysis of their genetic resources. We also used species distribution models (SDMs) for sororia to identify changes in this wild subspecies' distribution from the Holocene (∼6,000 years ago) to the present, and to assess the presence of suitable environmental conditions in previously proposed domestication sites. Genetic variation was similar among subspecies ( H E = 0.428 in sororia , and H E = 0.410 in argyrosperma ). Nine argyrosperma populations showed significant levels of inbreeding. Both subspecies are well differentiated, and genetic differentiation ( F ST ) among populations within each subspecies ranged from 0.152 to 0.652. Within argyrosperma we found three genetic groups (Northern Mexico, Yucatan Peninsula, including Michoacan and Veracruz, and Pacific coast plus Durango). We detected low

  1. Integration of georeferencing, habitat, sampling, and genetic data for documentation of wild plant genetic resources

    USDA-ARS?s Scientific Manuscript database

    Plant genetic resource collections provide novel materials to the breeding and research communities. Availability of detailed documentation of passport, phenotypic, and genetic data increases the value of the genebank accessions. Inclusion of georeferenced sources, habitats, and sampling data in co...

  2. Database resources of the National Center for Biotechnology Information

    PubMed Central

    2013-01-01

    In addition to maintaining the GenBank® nucleic acid sequence database, the National Center for Biotechnology Information (NCBI, http://www.ncbi.nlm.nih.gov) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the NCBI web site. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central, Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Primer-BLAST, COBALT, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, dbVar, Epigenomics, the Genetic Testing Registry, Genome and related tools, the Map Viewer, Model Maker, Evidence Viewer, Trace Archive, Sequence Read Archive, BioProject, BioSample, Retroviral Genotyping Tools, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus, Probe, Online Mendelian Inheritance in Animals, the Molecular Modeling Database, the Conserved Domain Database, the Conserved Domain Architecture Retrieval Tool, Biosystems, Protein Clusters and the PubChem suite of small molecule databases. Augmenting many of the web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of these resources can be accessed through the NCBI home page. PMID:23193264

  3. Database resources of the National Center for Biotechnology Information

    PubMed Central

    Acland, Abigail; Agarwala, Richa; Barrett, Tanya; Beck, Jeff; Benson, Dennis A.; Bollin, Colleen; Bolton, Evan; Bryant, Stephen H.; Canese, Kathi; Church, Deanna M.; Clark, Karen; DiCuccio, Michael; Dondoshansky, Ilya; Federhen, Scott; Feolo, Michael; Geer, Lewis Y.; Gorelenkov, Viatcheslav; Hoeppner, Marilu; Johnson, Mark; Kelly, Christopher; Khotomlianski, Viatcheslav; Kimchi, Avi; Kimelman, Michael; Kitts, Paul; Krasnov, Sergey; Kuznetsov, Anatoliy; Landsman, David; Lipman, David J.; Lu, Zhiyong; Madden, Thomas L.; Madej, Tom; Maglott, Donna R.; Marchler-Bauer, Aron; Karsch-Mizrachi, Ilene; Murphy, Terence; Ostell, James; O'Sullivan, Christopher; Panchenko, Anna; Phan, Lon; Pruitt, Don Preussm Kim D.; Rubinstein, Wendy; Sayers, Eric W.; Schneider, Valerie; Schuler, Gregory D.; Sequeira, Edwin; Sherry, Stephen T.; Shumway, Martin; Sirotkin, Karl; Siyan, Karanjit; Slotta, Douglas; Soboleva, Alexandra; Soussov, Vladimir; Starchenko, Grigory; Tatusova, Tatiana A.; Trawick, Bart W.; Vakatov, Denis; Wang, Yanli; Ward, Minghong; John Wilbur, W.; Yaschenko, Eugene; Zbicz, Kerry

    2014-01-01

    In addition to maintaining the GenBank® nucleic acid sequence database, the National Center for Biotechnology Information (NCBI, http://www.ncbi.nlm.nih.gov) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the NCBI Web site. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central, PubReader, Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link, Primer-BLAST, COBALT, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, dbVar, Epigenomics, the Genetic Testing Registry, Genome and related tools, the Map Viewer, Trace Archive, Sequence Read Archive, BioProject, BioSample, ClinVar, MedGen, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus, Probe, Online Mendelian Inheritance in Animals, the Molecular Modeling Database, the Conserved Domain Database, the Conserved Domain Architecture Retrieval Tool, Biosystems, Protein Clusters and the PubChem suite of small molecule databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All these resources can be accessed through the NCBI home page. PMID:24259429

  4. The National Coal Resource Assessment Overview

    USGS Publications Warehouse

    Pierce, Brenda S.; Dennen, Kristin O.

    2009-01-01

    The U.S. Geological Survey (USGS) has completed the National Coal Resource Assessment (NCRA), a multiyear project by the USGS Energy Resources Program, in partnership with State geological surveys in the coal producing regions of the United States. The NCRA is the first digital national coal-resource assessment. Coal beds and zones were assessed in five regions that account for more than 90 percent of the Nation's coal production - (1) the Appalachian Basin, (2) the Illinois Basin, (3) the Gulf Coastal Plain, (4) the Colorado Plateau, and (5) the Northern Rocky Mountains and Great Plains. The purpose of this Professional Paper, USGS Professional Paper 1625-F, is to present a tabulation and overview of the assessment results, insight into the methods used in the NCRA, and supplemental information on coal quality, economics, and other factors that affect coal production in the United States.

  5. The fewer and the better: prioritization of populations for conservation under limited resources, a genetic study with Borderea pyrenaica (Dioscoreaceae) in the Pyrenean National Park.

    PubMed

    Segarra-Moragues, J G; Catalán, P

    2010-03-01

    Taxa considered under low International Union for the Conservation of Nature categories of extinction risk often represent cases of concern to conservation biology. Their high relative abundance precludes management of the entire range due to limited economical resources. Therefore, they require a cost-effective management plan. Borderea pyrenaica (Dioscoreaceae), an endemic plant of the Central Pyrenees and pre-Pyrenees, reaches the French side of the Central Pyrenees on its narrow northernmost boundary at Gavarnie (Parc National des Pyrenées, PNP, France), where it is protected as Vulnerable and considered a priority species. We have used nuclear microsatellite population genetic data to design a management strategy for the 11 populations of B. pyrenaica present in this area and to identify Relevant Genetic Units for its Conservation. The 18 SSR loci analysed identified 56 alleles, 24 of which fulfilled the rarity criterion for this set of populations. Genetic structuring of populations and representativity values derived from regression analyses of probabilities of loss of rare alleles together support differentiation of the B. pyrenaica populations into different management units. Estimates derived from G(ST) values indicate that five populations would adequately represent the 99.9% of the variation relative to most common alleles whereas calculations based on representativity values indicated that these five populations should equate the proportion 2:2:1 from the three different phylogeographical subdivisions of Gavarnie (Western, Eastern-1 and Eastern-2 ranges). This scheme would allow the preservation of 98.21% of the total B. pyrenaica alleles present in Gavarnie, according to the post glacial history of its populations. This conservation genetic approach could be applied to other low-extinction risk categories of extremely rare and subalpine plants in need of regulatory plans in European National Parks and Natural Reserves.

  6. Genetic Resources in the “Calabaza Pipiana” Squash (Cucurbita argyrosperma) in Mexico: Genetic Diversity, Genetic Differentiation and Distribution Models

    PubMed Central

    Sánchez-de la Vega, Guillermo; Castellanos-Morales, Gabriela; Gámez, Niza; Hernández-Rosales, Helena S.; Vázquez-Lobo, Alejandra; Aguirre-Planter, Erika; Jaramillo-Correa, Juan P.; Montes-Hernández, Salvador; Lira-Saade, Rafael; Eguiarte, Luis E.

    2018-01-01

    Analyses of genetic variation allow understanding the origin, diversification and genetic resources of cultivated plants. Domesticated taxa and their wild relatives are ideal systems for studying genetic processes of plant domestication and their joint is important to evaluate the distribution of their genetic resources. Such is the case of the domesticated subspecies C. argyrosperma ssp. argyrosperma, known in Mexico as calabaza pipiana, and its wild relative C. argyrosperma ssp. sororia. The main aim of this study was to use molecular data (microsatellites) to assess the levels of genetic variation and genetic differentiation within and among populations of domesticated argyrosperma across its distribution in Mexico in comparison to its wild relative, sororia, and to identify environmental suitability in previously proposed centers of domestication. We analyzed nine unlinked nuclear microsatellite loci to assess levels of diversity and distribution of genetic variation within and among populations in 440 individuals from 19 populations of cultivated landraces of argyrosperma and from six wild populations of sororia, in order to conduct a first systematic analysis of their genetic resources. We also used species distribution models (SDMs) for sororia to identify changes in this wild subspecies’ distribution from the Holocene (∼6,000 years ago) to the present, and to assess the presence of suitable environmental conditions in previously proposed domestication sites. Genetic variation was similar among subspecies (HE = 0.428 in sororia, and HE = 0.410 in argyrosperma). Nine argyrosperma populations showed significant levels of inbreeding. Both subspecies are well differentiated, and genetic differentiation (FST) among populations within each subspecies ranged from 0.152 to 0.652. Within argyrosperma we found three genetic groups (Northern Mexico, Yucatan Peninsula, including Michoacan and Veracruz, and Pacific coast plus Durango). We detected low levels of gene

  7. Genetics education for health professionals: strategies and outcomes from a national initiative in the United Kingdom.

    PubMed

    Farndon, Peter A; Bennett, Catherine

    2008-04-01

    The National Health Service (NHS) National Genetics Education and Development Centre was established by the Department of Health in 2004 to help drive and co-ordinate genetics education for health professionals working outside specialist genetic services. This paper reviews the experiences and lessons learned to date. At the outset, it was clear that understanding the learning ethos, preferred delivery methods and attitudes towards genetics of different NHS healthcare groups was vital. We collected evidence by undertaking needs assessments with educators, practitioners and patients. We have determined the genetics knowledge, skills and attitudes which they said were needed and translated these into learning outcomes and workforce competences in a continuum of education. Beginning with core concepts introduced (and examined) pre-registration, the continuum continues with development of concepts post-registration as appropriate for role, leading to practical application and assessment of competences in the workplace. These are supported by a portfolio of resources which draw heavily on patient based scenarios to demonstrate to staff that genetics is relevant to their work, and to convince educators and policy makers that genetic education is likely to result in real clinical benefit. A long term educational policy, inclusive of learners, educationalists and their institutions must be evidence based, flexible and responsive to changes in workforce structure, provision of clinical services and conceptual and financial commitments to education. The engagement of national policy, regulatory and professional bodies is vital (www.geneticseducation.nhs.uk).

  8. GeneEd—A Genetics Educational Resource | NIH MedlinePlus the Magazine

    MedlinePlus

    ... of this page please turn Javascript on. Feature: Genetics 101 GeneEd — A Genetics Educational Resource Past Issues / Summer 2013 Table of ... GeneEd website as part of her lessons on genetics. A recently developed educational website about genetics— GeneEd. ...

  9. Idaho National Laboratory Cultural Resource Management Plan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Julie Braun Williams

    As a federal agency, the U.S. Department of Energy has been directed by Congress, the U.S. president, and the American public to provide leadership in the preservation of prehistoric, historic, and other cultural resources on the lands it administers. This mandate to preserve cultural resources in a spirit of stewardship for the future is outlined in various federal preservation laws, regulations, and guidelines such as the National Historic Preservation Act, the Archaeological Resources Protection Act, and the National Environmental Policy Act. The purpose of this Cultural Resource Management Plan is to describe how the Department of Energy, Idaho Operations Officemore » will meet these responsibilities at Idaho National Laboratory in southeastern Idaho. The Idaho National Laboratory is home to a wide variety of important cultural resources representing at least 13,500 years of human occupation in the southeastern Idaho area. These resources are nonrenewable, bear valuable physical and intangible legacies, and yield important information about the past, present, and perhaps the future. There are special challenges associated with balancing the preservation of these sites with the management and ongoing operation of an active scientific laboratory. The Department of Energy, Idaho Operations Office is committed to a cultural resource management program that accepts these challenges in a manner reflecting both the spirit and intent of the legislative mandates. This document is designed for multiple uses and is intended to be flexible and responsive to future changes in law or mission. Document flexibility and responsiveness will be assured through regular reviews and as-needed updates. Document content includes summaries of Laboratory cultural resource philosophy and overall Department of Energy policy; brief contextual overviews of Laboratory missions, environment, and cultural history; and an overview of cultural resource management practices. A series of

  10. Database resources of the National Center for Biotechnology Information

    PubMed Central

    2016-01-01

    The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank® nucleic acid sequence database and the PubMed database of citations and abstracts for published life science journals. Additional NCBI resources focus on literature (PubMed Central (PMC), Bookshelf and PubReader), health (ClinVar, dbGaP, dbMHC, the Genetic Testing Registry, HIV-1/Human Protein Interaction Database and MedGen), genomes (BioProject, Assembly, Genome, BioSample, dbSNP, dbVar, Epigenomics, the Map Viewer, Nucleotide, Probe, RefSeq, Sequence Read Archive, the Taxonomy Browser and the Trace Archive), genes (Gene, Gene Expression Omnibus (GEO), HomoloGene, PopSet and UniGene), proteins (Protein, the Conserved Domain Database (CDD), COBALT, Conserved Domain Architecture Retrieval Tool (CDART), the Molecular Modeling Database (MMDB) and Protein Clusters) and chemicals (Biosystems and the PubChem suite of small molecule databases). The Entrez system provides search and retrieval operations for most of these databases. Augmenting many of the web applications are custom implementations of the BLAST program optimized to search specialized datasets. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov. PMID:26615191

  11. 76 FR 19952 - Davy Crockett National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-11

    ... DEPARTMENT OF AGRICULTURE Davy Crockett National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of Public Meeting, Davy Crockett National Forest Resource Advisory Committee... 1972 (FACA), the U.S. Department of Agriculture, Forest Service, Davy Crockett National Forest Resource...

  12. Developing educational resources for population genetics in R: An open and collaborative approach

    USDA-ARS?s Scientific Manuscript database

    The R computing and statistical language community has developed a myriad of resources for conducting populations genetic analyses. However, resources for learning how to carry out population genetic analyses in R are scattered and often incomplete, which can make acquiring this skill unnecessarily ...

  13. 75 FR 42375 - Kisatchie National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-21

    ... DEPARTMENT OF AGRICULTURE Forest Service Kisatchie National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Kisatchie National Forest Resource..., Kisatchie National Forest, 2500 Shreveport Highway, Pineville, LA 71360. Comments may also be sent via e...

  14. 76 FR 9740 - Kisatchie National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    ... DEPARTMENT OF AGRICULTURE Forest Service Kisatchie National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Kisatchie National Forest Resource..., Kisatchie National Forest, 2500 Shreveport Highway, Pineville, LA 71360. Comments may also be sent via e...

  15. Putting the Pieces Together: Clinically Relevant Genetic and Genomic Resources for Hospitalists and Neonatologists.

    PubMed

    Miller, Rebecca; Khromykh, Alina; Babcock, Holly; Jenevein, Callie; Solomon, Benjamin D

    2017-02-01

    Genetic conditions are individually rare but are common in aggregate, and they often present in the neonatal and early pediatric periods. These conditions are often severe, can be difficult to diagnose and manage, and may heavily affect patients, families, health care systems, and society. Because of recent technological advances, the availability and uptake of genetic and genomic testing are increasing rapidly. However, there is a dearth of trained geneticists and genetic counselors to help guide and explain these conditions and relevant tests. To help hospitalists, neonatologists, and related practitioners navigate this complex and evolving field, we have compiled a list of free (mostly Web-based) resources relevant to the diagnosis and management of genetic conditions and related disorders. These resources, which we describe individually, can be useful for nongeneticist clinicians, and some also include material that can be used to explain concepts and conditions to patients or families. The resources presented are divided into the following categories (which overlap): general information, databases of genetic conditions, resources that can help generate differential diagnoses, databases of genetic testing laboratories (to help with logistics of ordering tests), information on newborn screening, and other resources. We also include a separate list of helpful textbooks and manuals. We conclude with 2 examples describing how some of these resources would be used by a pediatric hospitalist or neonatologist during the inpatient management of a child with a suspected genetic condition. Copyright © 2017 by the American Academy of Pediatrics.

  16. Proceedings of the third ISHS international symposium of plant genetic resources volume 1

    USDA-ARS?s Scientific Manuscript database

    The Third International ISHS Symposium on plant genetic resources occurred as Symposium 12 of the International Horticulture Congress in Lisbon, in August 2010. This symposium lasted4 days and emphasized new tools in plant genetic resource management. Six speakers gave invited presentations, and 30 ...

  17. Proceedings of the third ISHS international symposium on plant genetic resources volume 2

    USDA-ARS?s Scientific Manuscript database

    The Third International ISHS Symposium on plant genetic resources occurred as Symposium 12 of the International Horticulture Congress in Lisbon, in August 2010. This symposium lasted4 days and emphasized new tools in plant genetic resource management. Six speakers gave invited presentations, and 30 ...

  18. 76 FR 28949 - Kisatchie National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-19

    ... DEPARTMENT OF AGRICULTURE Forest Service Kisatchie National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Kisatchie National Forest Resource... begin at 6 p.m. ADDRESSES: The meeting will be held at the Kisatchie National Forest Supervisor's Office...

  19. Conserving and managing the trees of the future: genetic resources for Pacific Northwest forests.

    Treesearch

    Sally Duncan

    2003-01-01

    Genetic resource management has historically called for altering the genetic structure of plant populations through selection for traits of interest such as rapid growth. Although this is still a principal component of tree breeding programs in the Pacific Northwest, managing genetic resources now also brings a clear focus on retaining a broad diversity within and...

  20. Standards of Practice: Applying Genetics and Genomics Resources to Oncology
.

    PubMed

    Kerber, Alice S; Ledbetter, Nancy J

    2017-04-01

    Knowledge about genetics and genomics and its application to oncology care is rapidly expanding and evolving. As a result, oncology nurses at all levels must develop and maintain their knowledge of genetics and genomics, as well as be aware of resources to guide practice. This article focuses on implementation of the standards described in the updated Genetics/Genomics Nursing: Scope and Standards of Practice by the basic practitioner.
.

  1. National Patterns of Science and Technology Resources 1981.

    ERIC Educational Resources Information Center

    Chirichiello, John; Crowley, Michael

    An overview of two science and technology resources (financial support and scientific/technical personnel) is presented, based on a series of National Science Foundation (NSF) surveys on research and development (R&D) resources and scientific/technical personnel in the United States. Areas addressed related to national perspectives of R&D…

  2. Domestication to Crop Improvement: Genetic Resources for Sorghum and Saccharum (Andropogoneae)

    PubMed Central

    Dillon, Sally L.; Shapter, Frances M.; Henry, Robert J.; Cordeiro, Giovanni; Izquierdo, Liz; Lee, L. Slade

    2007-01-01

    Background Both sorghum (Sorghum bicolor) and sugarcane (Saccharum officinarum) are members of the Andropogoneae tribe in the Poaceae and are each other's closest relatives amongst cultivated plants. Both are relatively recent domesticates and comparatively little of the genetic potential of these taxa and their wild relatives has been captured by breeding programmes to date. This review assesses the genetic gains made by plant breeders since domestication and the progress in the characterization of genetic resources and their utilization in crop improvement for these two related species. Genetic Resources The genome of sorghum has recently been sequenced providing a great boost to our knowledge of the evolution of grass genomes and the wealth of diversity within S. bicolor taxa. Molecular analysis of the Sorghum genus has identified close relatives of S. bicolor with novel traits, endosperm structure and composition that may be used to expand the cultivated gene pool. Mutant populations (including TILLING populations) provide a useful addition to genetic resources for this species. Sugarcane is a complex polyploid with a large and variable number of copies of each gene. The wild relatives of sugarcane represent a reservoir of genetic diversity for use in sugarcane improvement. Techniques for quantitative molecular analysis of gene or allele copy number in this genetically complex crop have been developed. SNP discovery and mapping in sugarcane has been advanced by the development of high-throughput techniques for ecoTILLING in sugarcane. Genetic linkage maps of the sugarcane genome are being improved for use in breeding selection. The improvement of both sorghum and sugarcane will be accelerated by the incorporation of more diverse germplasm into the domesticated gene pools using molecular tools and the improved knowledge of these genomes. PMID:17766842

  3. Applying the Visitor Experience and Resource Protection (VERP) framework to cultural resources in the national parks

    Treesearch

    William Valliere; Robert Manning

    2003-01-01

    The National Park Service has developed the Visitor Experience and Resource Protection (VERP) framework for addressing carrying capacity in the National Parks. This framework has been successfully applied to natural and recreational resources in diverse units of the National Park System. However, most units of the National Park System also contain significant cultural...

  4. Idaho National Laboratory Cultural Resource Management Plan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lowrey, Diana Lee

    As a federal agency, the U.S. Department of Energy has been directed by Congress, the U.S. president, and the American public to provide leadership in the preservation of prehistoric, historic, and other cultural resources on the lands it administers. This mandate to preserve cultural resources in a spirit of stewardship for the future is outlined in various federal preservation laws, regulations, and guidelines such as the National Historic Preservation Act, the Archaeological Resources Protection Act, and the National Environmental Policy Act. The purpose of this Cultural Resource Management Plan is to describe how the Department of Energy, Idaho Operations Officemore » will meet these responsibilities at the Idaho National Laboratory. This Laboratory, which is located in southeastern Idaho, is home to a wide variety of important cultural resources representing at least 13,500 years of human occupation in the southeastern Idaho area. These resources are nonrenewable; bear valuable physical and intangible legacies; and yield important information about the past, present, and perhaps the future. There are special challenges associated with balancing the preservation of these sites with the management and ongoing operation of an active scientific laboratory. The Department of Energy, Idaho Operations Office is committed to a cultural resource management program that accepts these challenges in a manner reflecting both the spirit and intent of the legislative mandates. This document is designed for multiple uses and is intended to be flexible and responsive to future changes in law or mission. Document flexibility and responsiveness will be assured through annual reviews and as-needed updates. Document content includes summaries of Laboratory cultural resource philosophy and overall Department of Energy policy; brief contextual overviews of Laboratory missions, environment, and cultural history; and an overview of cultural resource management practices. A series of

  5. Idaho National Laboratory Cultural Resource Management Plan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lowrey, Diana Lee

    2009-02-01

    As a federal agency, the U.S. Department of Energy has been directed by Congress, the U.S. president, and the American public to provide leadership in the preservation of prehistoric, historic, and other cultural resources on the lands it administers. This mandate to preserve cultural resources in a spirit of stewardship for the future is outlined in various federal preservation laws, regulations, and guidelines such as the National Historic Preservation Act, the Archaeological Resources Protection Act, and the National Environmental Policy Act. The purpose of this Cultural Resource Management Plan is to describe how the Department of Energy, Idaho Operations Officemore » will meet these responsibilities at the Idaho National Laboratory. This Laboratory, which is located in southeastern Idaho, is home to a wide variety of important cultural resources representing at least 13,500 years of human occupation in the southeastern Idaho area. These resources are nonrenewable; bear valuable physical and intangible legacies; and yield important information about the past, present, and perhaps the future. There are special challenges associated with balancing the preservation of these sites with the management and ongoing operation of an active scientific laboratory. The Department of Energy, Idaho Operations Office is committed to a cultural resource management program that accepts these challenges in a manner reflecting both the spirit and intent of the legislative mandates. This document is designed for multiple uses and is intended to be flexible and responsive to future changes in law or mission. Document flexibility and responsiveness will be assured through annual reviews and as-needed updates. Document content includes summaries of Laboratory cultural resource philosophy and overall Department of Energy policy; brief contextual overviews of Laboratory missions, environment, and cultural history; and an overview of cultural resource management practices. A series of

  6. A Belated Green Revolution for Cannabis: Virtual Genetic Resources to Fast-Track Cultivar Development

    PubMed Central

    Welling, Matthew T.; Shapter, Tim; Rose, Terry J.; Liu, Lei; Stanger, Rhia; King, Graham J.

    2016-01-01

    Cannabis is a predominantly diecious phenotypically diverse domesticated genus with few if any extant natural populations. International narcotics conventions and associated legislation have constrained the establishment, characterization, and use of Cannabis genetic resource collections. This has resulted in the underutilization of genepool variability in cultivar development and has limited the inclusion of secondary genepools associated with genetic improvement strategies of the Green Revolution. The structured screening of ex situ germplasm and the exploitation of locally-adapted intraspecific traits is expected to facilitate the genetic improvement of Cannabis. However, limited attempts have been made to establish the full extent of genetic resources available for pre-breeding. We present a thorough critical review of Cannabis ex situ genetic resources, and discuss recommendations for conservation, pre-breeding characterization, and genetic analysis that will underpin future cultivar development. We consider East Asian germplasm to be a priority for conservation based on the prolonged historical cultivation of Cannabis in this region over a range of latitudes, along with the apparent high levels of genetic diversity and relatively low representation in published genetic resource collections. Seed cryopreservation could improve conservation by reducing hybridization and genetic drift that may occur during Cannabis germplasm regeneration. Given the unique legal status of Cannabis, we propose the establishment of a global virtual core collection based on the collation of consistent and comprehensive provenance meta-data and the adoption of high-throughput DNA sequencing technologies. This would enable representative core collections to be used for systematic phenotyping, and so underpin breeding strategies for the genetic improvement of Cannabis. PMID:27524992

  7. A Belated Green Revolution for Cannabis: Virtual Genetic Resources to Fast-Track Cultivar Development.

    PubMed

    Welling, Matthew T; Shapter, Tim; Rose, Terry J; Liu, Lei; Stanger, Rhia; King, Graham J

    2016-01-01

    Cannabis is a predominantly diecious phenotypically diverse domesticated genus with few if any extant natural populations. International narcotics conventions and associated legislation have constrained the establishment, characterization, and use of Cannabis genetic resource collections. This has resulted in the underutilization of genepool variability in cultivar development and has limited the inclusion of secondary genepools associated with genetic improvement strategies of the Green Revolution. The structured screening of ex situ germplasm and the exploitation of locally-adapted intraspecific traits is expected to facilitate the genetic improvement of Cannabis. However, limited attempts have been made to establish the full extent of genetic resources available for pre-breeding. We present a thorough critical review of Cannabis ex situ genetic resources, and discuss recommendations for conservation, pre-breeding characterization, and genetic analysis that will underpin future cultivar development. We consider East Asian germplasm to be a priority for conservation based on the prolonged historical cultivation of Cannabis in this region over a range of latitudes, along with the apparent high levels of genetic diversity and relatively low representation in published genetic resource collections. Seed cryopreservation could improve conservation by reducing hybridization and genetic drift that may occur during Cannabis germplasm regeneration. Given the unique legal status of Cannabis, we propose the establishment of a global virtual core collection based on the collation of consistent and comprehensive provenance meta-data and the adoption of high-throughput DNA sequencing technologies. This would enable representative core collections to be used for systematic phenotyping, and so underpin breeding strategies for the genetic improvement of Cannabis.

  8. Climbing the Ladder: Experience with Developing a Large Group Genetic Counselor Career Ladder at Children's National Health System.

    PubMed

    Kofman, Laura; Seprish, Mary Beth; Summar, Marshall

    2016-08-01

    Children's National Health System (CNHS) is a not-for-profit pediatric hospital that employs around twenty genetic counselors in a range of specialties, including clinical pediatric, neurology, fetal medicine, research, and laboratory. CNHS lacked a structured system of advancement for their genetic counselors; therefore, a formal career ladder was proposed by the genetic counselors based on years of experience, responsibility, and job performance. This career ladder utilized monetary, academic, and seniority incentives to encourage advancement and continue employment at CNHS. The creation and ultimate approval of the career ladder required direct input from genetic counselors, Department Chairs, and Human Resource personnel. The establishment of a genetic counselor career ladder at CNHS will hopefully benefit the profession of genetic counselors as a whole and allow other facilities to create and maintain their own career ladder to meet the needs of the growing, competitive, field of genetic counseling.

  9. 76 FR 28210 - Chippewa National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-16

    ... DEPARTMENT OF AGRICULTURE Forest Service Chippewa National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Chippewa National Forest Resource... provide advice and recommendations to the Forest Service concerning projects and funding consistent with...

  10. Forest resources of the Forest resources of the Apache-Sitgreaves National Forest

    Treesearch

    Paul Rogers

    2008-01-01

    The Interior West Forest Inventory and Analysis (IWFIA) program of the USDA Forest Service, Rocky Mountain Research Station, as part of its national Forest Inventory and Analysis (FIA) duties, conducted forest resource inventories of the Southwestern Region (Region 3) National Forests. This report presents highlights of the Apache-Sitgreaves National Forest...

  11. National coalition for health professional education in genetics.

    PubMed

    Kenner, C

    1998-11-01

    With the explosion of genetic information, there has been a recognized need for more genetic knowledge among health care professionals. The National Coalition for Health Professional Education in Genetics (NCHPEG) was established in 1996 to address this need. This article briefly outlines the mission of this Coalition and gives an overview of its relationship to acute and critical care nurses.

  12. Forest resources of the Clearwater National Forest

    Treesearch

    Ryan P. Hughes

    2011-01-01

    The Interior West Forest Inventory and Analysis (IWFIA) Program of the USDA Forest Service, Rocky Mountain Research Station, as part of our National Forest System cooperative inventories, conducted a forest resource inventory on the Clearwater National Forest using a nationally standardized mapped-plot design (for more details see section "Inventory methods...

  13. Forest resources of the Prescott National Forest

    Treesearch

    Paul Rogers

    2003-01-01

    The Interior West Forest Inventory and Analysis (IWFIA) program of the USDA Forest Service, Rocky Mountain Research Station, as part of its national Forest Inventory and Analysis (FIA) duties, conducted forest resource inventories of the Southwestern Region (Region 3) National Forests. This report presents highlights of the Prescott National Forest 1996...

  14. Idaho National Laboratory Cultural Resource Monitoring Report for 2013

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Williams, Julie B.

    2013-10-01

    This report describes the cultural resource monitoring activities of the Idaho National Laboratory’s (INL) Cultural Resource Management (CRM) Office during 2013. Throughout the year, thirty-eight cultural resource localities were revisited including: two locations with Native American human remains, one of which is also a cave; fourteen additional caves; seven prehistoric archaeological sites ; four historic archaeological sites; one historic trail; one nuclear resource (Experimental Breeder Reactor-I, a designated National Historic Landmark); and nine historic structures located at the Central Facilities Area. Of the monitored resources, thirty-three were routinely monitored, and five were monitored to assess project compliance with cultural resourcemore » recommendations along with the effects of ongoing project activities. On six occasions, ground disturbing activities within the boundaries of the Power Burst Facility/Critical Infrastructure Test Range Complex (PBF/CITRC) were observed by INL CRM staff prepared to respond to any additional finds of Native American human remains. In addition, two resources were visited more than once as part of the routine monitoring schedule or to monitor for additional damage. Throughout the year, most of the cultural resources monitored had no visual adverse changes resulting in Type 1determinations. However, Type 2 impacts were noted at eight sites, indicating that although impacts were noted or that a project was operating outside of culturally cleared limitations, cultural resources retained integrity and noted impacts did not threaten National Register eligibility. No new Type 3 or any Type 4 impacts that adversely impacted cultural resources and threatened National Register eligibility were observed at cultural resources monitored in 2013.« less

  15. Forest resources of the Bighorn National Forest

    Treesearch

    Christopher Witt

    2008-01-01

    The Interior West Forest Inventory and Analysis (IWFIA) Program of the USDA Forest Service, Rocky Mountain Research Station, as part of our National Forest System cooperative inventories, conducted a forest resource inventory on the Bighorn National Forest (Bighorn) using a nationally standardized mapped-plot design. This report presents the highlights of this 2000...

  16. Forest resources of the Tonto National Forest

    Treesearch

    John D. Shaw

    2004-01-01

    The Interior West Forest Inventory and Analysis (IWFIA) program of the USDA Forest Service, Rocky Mountain Research Station, as part of its national Forest Inventory and Analysis (FIA) duties, conducted forest resource inventories of the Southwestern Region (Region 3) National Forests. This report presents highlights of the Tonto National Forest 1996 inventory...

  17. Forest resources of the Shoshone National Forest

    Treesearch

    James Menlove

    2008-01-01

    The Interior West Forest Inventory and Analysis (IWFIA) Program of the USDA Forest Service, Rocky Mountain Research Station, as part of our National Forest System cooperative inventories, conducted a forest resource inventory on the Shoshone National Forest using a nationally standardized mapped-plot design. This report presents the highlights of this 1999 inventory...

  18. Forest resources of the Lincoln National Forest

    Treesearch

    John D. Shaw

    2006-01-01

    The Interior West Forest Inventory and Analysis (IWFIA) program of the USDA Forest Service, Rocky Mountain Research Station, as part of its national Forest Inventory and Analysis (FIA) duties, conducted forest resource inventories of the Southwestern Region (Region 3) National Forests. This report presents highlights of the Lincoln National Forest 1997 inventory...

  19. Forest resources of the Gila National Forest

    Treesearch

    John D. Shaw

    2008-01-01

    The Interior West Forest Inventory and Analysis (IWFIA) program of the USDA Forest Service, Rocky Mountain Research Station, as part of its national Forest Inventory and Analysis (FIA) duties, conducted forest resource inventories of the Southwestern Region (Region 3) National Forests. This report presents highlights of the Gila National Forest 1994 inventory including...

  20. Coverage of genetic technologies under national health reform.

    PubMed Central

    Mehlman, M. J.; Botkin, J. R.; Scarrow, A.; Woodhall, A.; Kass, J.; Siebenschuh, E.

    1994-01-01

    This article examines the extent to which the technologies expected to emerge from genetic research are likely to be covered under Government-mandated health insurance programs such as those being proposed by advocates of national health reform. Genetic technologies are divided into three broad categories; genetic information services, including screening, testing, and counseling; experimental technologies; and gene therapy. This article concludes that coverage of these technologies under national health reform is uncertain. The basic benefits packages provided for in the major health reform plans are likely to provide partial coverage of experimental technologies; relatively broad coverage of information services; and varying coverage of gene therapies, on the basis of an evaluation of their costs, benefits, and the degree to which they raise objections on political and religious grounds. Genetic services that are not included in the basic benefits package will be available only to those who can purchase supplemental insurance or to those who can purchase the services with personal funds. The resulting multitiered system of access to genetic services raises serious questions of fairness. PMID:7977343

  1. 34 CFR 656.1 - What is the National Resource Centers Program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false What is the National Resource Centers Program? 656.1... POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION NATIONAL RESOURCE CENTERS PROGRAM FOR FOREIGN LANGUAGE AND AREA... Centers Program? Under the National Resource Centers Program for Foreign Language and Areas Studies or...

  2. 34 CFR 656.1 - What is the National Resource Centers Program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false What is the National Resource Centers Program? 656.1... POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION NATIONAL RESOURCE CENTERS PROGRAM FOR FOREIGN LANGUAGE AND AREA... Centers Program? Under the National Resource Centers Program for Foreign Language and Areas Studies or...

  3. 34 CFR 656.1 - What is the National Resource Centers Program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What is the National Resource Centers Program? 656.1... POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION NATIONAL RESOURCE CENTERS PROGRAM FOR FOREIGN LANGUAGE AND AREA... Centers Program? Under the National Resource Centers Program for Foreign Language and Areas Studies or...

  4. 34 CFR 656.1 - What is the National Resource Centers Program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false What is the National Resource Centers Program? 656.1... POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION NATIONAL RESOURCE CENTERS PROGRAM FOR FOREIGN LANGUAGE AND AREA... Centers Program? Under the National Resource Centers Program for Foreign Language and Areas Studies or...

  5. 34 CFR 656.1 - What is the National Resource Centers Program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false What is the National Resource Centers Program? 656.1... POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION NATIONAL RESOURCE CENTERS PROGRAM FOR FOREIGN LANGUAGE AND AREA... Centers Program? Under the National Resource Centers Program for Foreign Language and Areas Studies or...

  6. Strategies for conserving forest genetic resources in the face of climate change

    Treesearch

    John Bradley St. Clair; Glenn Thomas Howe

    2011-01-01

    Conservation of genetic diversity is important for continued evolution of populations to new environments, as well as continued availability of traits of interest in genetic improvement programs. Rapidly changing climates present new threats to the conservation of forest genetic resources. We can no longer assume that in situ reserves will continue to preserve existing...

  7. ILDgenDB: integrated genetic knowledge resource for interstitial lung diseases (ILDs).

    PubMed

    Mishra, Smriti; Shah, Mohammad I; Sarkar, Malay; Asati, Nimisha; Rout, Chittaranjan

    2018-01-01

    Interstitial lung diseases (ILDs) are a diverse group of ∼200 acute and chronic pulmonary disorders that are characterized by variable amounts of inflammation, fibrosis and architectural distortion with substantial morbidity and mortality. Inaccurate and delayed diagnoses increase the risk, especially in developing countries. Studies have indicated the significant roles of genetic elements in ILDs pathogenesis. Therefore, the first genetic knowledge resource, ILDgenDB, has been developed with an objective to provide ILDs genetic data and their integrated analyses for the better understanding of disease pathogenesis and identification of diagnostics-based biomarkers. This resource contains literature-curated disease candidate genes (DCGs) enriched with various regulatory elements that have been generated using an integrated bioinformatics workflow of databases searches, literature-mining and DCGs-microRNA (miRNAs)-single nucleotide polymorphisms (SNPs) association analyses. To provide statistical significance to disease-gene association, ILD-specificity index and hypergeomatric test scores were also incorporated. Association analyses of miRNAs, SNPs and pathways responsible for the pathogenesis of different sub-classes of ILDs were also incorporated. Manually verified 299 DCGs and their significant associations with 1932 SNPs, 2966 miRNAs and 9170 miR-polymorphisms were also provided. Furthermore, 216 literature-mined and proposed biomarkers were identified. The ILDgenDB resource provides user-friendly browsing and extensive query-based information retrieval systems. Additionally, this resource also facilitates graphical view of predicted DCGs-SNPs/miRNAs and literature associated DCGs-ILDs interactions for each ILD to facilitate efficient data interpretation. Outcomes of analyses suggested the significant involvement of immune system and defense mechanisms in ILDs pathogenesis. This resource may potentially facilitate genetic-based disease monitoring and

  8. Promoting Utilization of Saccharum spp. Genetic Resources through Genetic Diversity Analysis and Core Collection Construction

    PubMed Central

    Pathak, Bhuvan; Ayala-Silva, Tomas; Yang, Xiping; Todd, James; Glynn, Neil C.; Kuhn, David N.; Glaz, Barry; Gilbert, Robert A.; Comstock, Jack C.; Wang, Jianping

    2014-01-01

    Sugarcane (Saccharum spp.) and other members of Saccharum spp. are attractive biofuel feedstocks. One of the two World Collections of Sugarcane and Related Grasses (WCSRG) is in Miami, FL. This WCSRG has 1002 accessions, presumably with valuable alleles for biomass, other important agronomic traits, and stress resistance. However, the WCSRG has not been fully exploited by breeders due to its lack of characterization and unmanageable population. In order to optimize the use of this genetic resource, we aim to 1) genotypically evaluate all the 1002 accessions to understand its genetic diversity and population structure and 2) form a core collection, which captures most of the genetic diversity in the WCSRG. We screened 36 microsatellite markers on 1002 genotypes and recorded 209 alleles. Genetic diversity of the WCSRG ranged from 0 to 0.5 with an average of 0.304. The population structure analysis and principal coordinate analysis revealed three clusters with all S. spontaneum in one cluster, S. officinarum and S. hybrids in the second cluster and mostly non-Saccharum spp. in the third cluster. A core collection of 300 accessions was identified which captured the maximum genetic diversity of the entire WCSRG which can be further exploited for sugarcane and energy cane breeding. Sugarcane and energy cane breeders can effectively utilize this core collection for cultivar improvement. Further, the core collection can provide resources for forming an association panel to evaluate the traits of agronomic and commercial importance. PMID:25333358

  9. National-Scale Wind Resource Assessment for Power Generation (Presentation)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baring-Gould, E. I.

    2013-08-01

    This presentation describes the current standards for conducting a national-scale wind resource assessment for power generation, along with the risk/benefit considerations to be considered when beginning a wind resource assessment. The presentation describes changes in turbine technology and viable wind deployment due to more modern turbine technology and taller towers and shows how the Philippines national wind resource assessment evolved over time to reflect changes that arise from updated technologies and taller towers.

  10. Why preserve and evaluate genetic resources in peanut?

    USDA-ARS?s Scientific Manuscript database

    Peanuts are produced in more than 100 countries with a total global total production in 2010 of 37,953,949 metric tons (FAO statistics, 2010). Because peanut is an important crop, it is imperative that its germplasm be preserved in order to conserve the genetic diversity and provide a resource to i...

  11. Database resources of the National Center for Biotechnology Information.

    PubMed

    2016-01-04

    The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank(®) nucleic acid sequence database and the PubMed database of citations and abstracts for published life science journals. Additional NCBI resources focus on literature (PubMed Central (PMC), Bookshelf and PubReader), health (ClinVar, dbGaP, dbMHC, the Genetic Testing Registry, HIV-1/Human Protein Interaction Database and MedGen), genomes (BioProject, Assembly, Genome, BioSample, dbSNP, dbVar, Epigenomics, the Map Viewer, Nucleotide, Probe, RefSeq, Sequence Read Archive, the Taxonomy Browser and the Trace Archive), genes (Gene, Gene Expression Omnibus (GEO), HomoloGene, PopSet and UniGene), proteins (Protein, the Conserved Domain Database (CDD), COBALT, Conserved Domain Architecture Retrieval Tool (CDART), the Molecular Modeling Database (MMDB) and Protein Clusters) and chemicals (Biosystems and the PubChem suite of small molecule databases). The Entrez system provides search and retrieval operations for most of these databases. Augmenting many of the web applications are custom implementations of the BLAST program optimized to search specialized datasets. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov. Published by Oxford University Press on behalf of Nucleic Acids Research 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  12. A portable expression resource for engineering cross-species genetic circuits and pathways

    PubMed Central

    Kushwaha, Manish; Salis, Howard M.

    2015-01-01

    Genetic circuits and metabolic pathways can be reengineered to allow organisms to process signals and manufacture useful chemicals. However, their functions currently rely on organism-specific regulatory parts, fragmenting synthetic biology and metabolic engineering into host-specific domains. To unify efforts, here we have engineered a cross-species expression resource that enables circuits and pathways to reuse the same genetic parts, while functioning similarly across diverse organisms. Our engineered system combines mixed feedback control loops and cross-species translation signals to autonomously self-regulate expression of an orthogonal polymerase without host-specific promoters, achieving nontoxic and tuneable gene expression in diverse Gram-positive and Gram-negative bacteria. Combining 50 characterized system variants with mechanistic modelling, we show how the cross-species expression resource's dynamics, capacity and toxicity are controlled by the control loops' architecture and feedback strengths. We also demonstrate one application of the resource by reusing the same genetic parts to express a biosynthesis pathway in both model and non-model hosts. PMID:26184393

  13. AgBioData | National Agricultural Library

    Science.gov Websites

    Skip to main content Home National Agricultural Library United States Department of Agriculture Ag National Invertebrate Genetic Resources Insects impact American agriculture both as destructive and , biotypes, and other genetic entities and to document their different interactions with agriculture and the

  14. PatGen--a consolidated resource for searching genetic patent sequences.

    PubMed

    Rouse, Richard J D; Castagnetto, Jesus; Niedner, Roland H

    2005-04-15

    Compared to the wealth of online resources covering genomic, proteomic and derived data the Bioinformatics community is rather underserved when it comes to patent information related to biological sequences. The current online resources are either incomplete or rather expensive. This paper describes, PatGen, an integrated database containing data from bioinformatic and patent resources. This effort addresses the inconsistency of publicly available genetic patent data coverage by providing access to a consolidated dataset. PatGen can be searched at http://www.patgendb.com rjdrouse@patentinformatics.com.

  15. Natural resource assessment: an approach to science based planning in national parks

    USGS Publications Warehouse

    Mahan, C.G.; Vanderhorst, J.P.; Young, J.A.

    2009-01-01

    We conducted a natural resource assessment at two national parks, New River Gorge National River and Shenandoah National Park, to help meet the goals of the Natural Resource Challenge-a program to help strengthen natural resource management at national parks. We met this challenge by synthesizing and interpreting natural resource information for planning purposes and we identified information gaps and natural significance of resources. We identified a variety of natural resources at both parks as being globally and/or nationally significant, including large expanses of unfragmented, mixed-mesophytic forests that qualify for wilderness protection, rare plant communities, diverse assemblages of neotropical migratory birds and salamanders, and outstanding aquatic recreational resources. In addition, these parks function, in part, as ecological reserves for plants in and wildlife. With these significant natural resources in mind, we also developed a suite of natural resource management recommendations in light of increasing threats from within and outside park boundaries. We hope that our approach can provide a blueprint for natural resource conservation at publically owned lands.

  16. Natural resource assessment: an approach to science based planning in national parks.

    PubMed

    Mahan, Carolyn G; Vanderhorst, James P; Young, John A

    2009-06-01

    We conducted a natural resource assessment at two national parks, New River Gorge National River and Shenandoah National Park, to help meet the goals of the Natural Resource Challenge--a program to help strengthen natural resource management at national parks. We met this challenge by synthesizing and interpreting natural resource information for planning purposes and we identified information gaps and natural significance of resources. We identified a variety of natural resources at both parks as being globally and/or nationally significant, including large expanses of unfragmented, mixed-mesophytic forests that qualify for wilderness protection, rare plant communities, diverse assemblages of neotropical migratory birds and salamanders, and outstanding aquatic recreational resources. In addition, these parks function, in part, as ecological reserves for plants in and wildlife. With these significant natural resources in mind, we also developed a suite of natural resource management recommendations in light of increasing threats from within and outside park boundaries. We hope that our approach can provide a blueprint for natural resource conservation at publically owned lands.

  17. Idaho National Laboratory Cultural Resource Monitoring Report for FY 2009

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brenda R. Pace; Julie B. Braun

    2009-10-01

    This report describes the cultural resource monitoring activities of the Idaho National Laboratory’s (INL) Cultural Resource Management (CRM) Office during fiscal year 2009 (FY 2009). Throughout the year, thirty-eight cultural resource localities were revisited including: two locations with Native American human remains, one of which is a cave, two additional caves, twenty-two prehistoric archaeological sites, six historic homesteads, two historic stage stations, two historic trails, and two nuclear resources, including Experimental Breeder Reactor-I, which is a designated National Historic Landmark. Several INL project areas were also monitored in FY 2009 to assess project compliance with cultural resource recommendations and monitormore » the effects of ongoing project activities. Although impacts were documented at a few locations and trespassing citations were issued in one instance, no significant adverse effects that would threaten the National Register eligibility of any resources were observed. Monitoring also demonstrated that several INL projects generally remain in compliance with recommendations to protect cultural resources.« less

  18. The National Aquatic Resource Surveys (NARS)

    EPA Pesticide Factsheets

    The National Aquatic Resource Surveys (NARS) are statistical surveys designed to assess the status of and changes in quality of the nation’s coastal waters, lakes and reservoirs, rivers and streams, and wetlands.

  19. Analysis of genetic diversity of rapeseed genetic resources in Japan and core collection construction

    PubMed Central

    Chen, Ruikun; Hara, Takashi; Ohsawa, Ryo; Yoshioka, Yosuke

    2017-01-01

    Diversity analysis of rapeseed accessions preserved in the Japanese Genebank can provide valuable information for breeding programs. In this study, 582 accessions were genotyped with 30 SSR markers covering all 19 rapeseed chromosomes. These markers amplified 311 alleles (10.37 alleles per marker; range, 3–39). The genetic diversity of Japanese accessions was lower than that of overseas accessions. Analysis of molecular variance indicated significant genetic differentiation between Japanese and overseas accessions. Small but significant differences were found among geographical groups in Japan, and genetic differentiation tended to increase with geographical distance. STRUCTURE analysis indicated the presence of two main genetic clusters in the NARO rapeseed collection. With the membership probabilities threshold, 227 accessions mostly originating from overseas were assigned to one subgroup, and 276 accessions mostly originating from Japan were assigned to the other subgroup. The remaining 79 accessions are assigned to admixed group. The core collection constructed comprises 96 accessions of diverse origin. It represents the whole collection well and thus it may be useful for rapeseed genetic research and breeding programs. The core collection improves the efficiency of management, evaluation, and utilization of genetic resources. PMID:28744177

  20. Genetics Home Reference: hyperprolinemia

    MedlinePlus

    ... Hyperprolinemia type 1 Orphanet: Hyperprolinemia type 2 Screening, Technology and Research in Genetics Patient Support and Advocacy Resources (3 links) Children Living with Inherited Metabolic Diseases National Organization for ...

  1. The Contribution of Buckwheat Genetic Resources to Health and Dietary Diversity

    PubMed Central

    Sytar, Oksana; Brestic, Marian; Zivcak, Marek; Tran, Lam-Son Phan

    2016-01-01

    Despite several reports on the beneficial effects of buckwheat in prevention of human diseases, little attention has been devoted to the variability of biochemical and physiological traits in different buckwheat genetic resources. This review describes the biochemical evaluation of buckwheat genetic resources and the identification of elite genotypes for plant breeding and exploitation. The various types of bioactive compounds present in different varieties provide basic background information needed for the efficient production of buckwheat foods with added value. In this review, we will provide an integrated view of the biochemistry of bioactive compounds of buckwheat plants of different origin, especially of fagopyrin, proteins and amino acids, as well as of other phenolic compounds including rutin and chlorogenic acid. In addition to the genetic background, the effect of different growth conditions is discussed. The health effects of fagopyrin, phenolic acids, specific proteins and rutin are also presented. PMID:27252586

  2. National assessment of geologic carbon dioxide storage resources: results

    USGS Publications Warehouse

    ,

    2013-01-01

    In 2012, the U.S. Geological Survey (USGS) completed an assessment of the technically accessible storage resources (TASR) for carbon dioxide (CO2) in geologic formations underlying the onshore and State waters area of the United States. The formations assessed are at least 3,000 feet (914 meters) below the ground surface. The TASR is an estimate of the CO2 storage resource that may be available for CO2 injection and storage that is based on present-day geologic and hydrologic knowledge of the subsurface and current engineering practices. Individual storage assessment units (SAUs) for 36 basins were defined on the basis of geologic and hydrologic characteristics outlined in the assessment methodology of Brennan and others (2010, USGS Open-File Report 2010–1127) and the subsequent methodology modification and implementation documentation of Blondes, Brennan, and others (2013, USGS Open-File Report 2013–1055). The mean national TASR is approximately 3,000 metric gigatons (Gt). The estimate of the TASR includes buoyant trapping storage resources (BSR), where CO2 can be trapped in structural or stratigraphic closures, and residual trapping storage resources, where CO2 can be held in place by capillary pore pressures in areas outside of buoyant traps. The mean total national BSR is 44 Gt. The residual storage resource consists of three injectivity classes based on reservoir permeability: residual trapping class 1 storage resource (R1SR) represents storage in rocks with permeability greater than 1 darcy (D); residual trapping class 2 storage resource (R2SR) represents storage in rocks with moderate permeability, defined as permeability between 1 millidarcy (mD) and 1 D; and residual trapping class 3 storage resource (R3SR) represents storage in rocks with low permeability, defined as permeability less than 1 mD. The mean national storage resources for rocks in residual trapping classes 1, 2, and 3 are 140 Gt, 2,700 Gt, and 130 Gt, respectively. The known recovery

  3. Journal Articles Applying National Aquatic Resource Survey Data

    EPA Pesticide Factsheets

    The National Aquatic Resource Surveys (NARS) data are being used and applied above and beyond the regional and national assessments. This page includes a list of recent journal articles that reference NARS data.

  4. 75 FR 69046 - Bridger-Teton National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... DEPARTMENT OF AGRICULTURE Forest Service Bridger-Teton National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Bridger-Teton Resource Advisory... sent to Tracy Hollingshead, Bridger-Teton National Forest, 308 Hwy 189 North, Kemmerer, WY 83101...

  5. 76 FR 13975 - Bridger-Teton National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ... DEPARTMENT OF AGRICULTURE Forest Service Bridger-Teton National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Bridger-Teton Resource Advisory... to Tracy Hollingshead, Bridger-Teton National Forest, 308 Hwy 189 North, Kemmerer, WY 83101. Comments...

  6. Forest resources of the Bitterroot National Forest

    Treesearch

    Tracey S. Frescino

    2008-01-01

    The Interior West Resource Inventory, Monitoring, and Evaluation (IWRIME) Program of the USDA Forest Service, Rocky Mountain Research Station (formerly the Intermountain Research Station), as part of its national Forest Inventory and Analysis (FIA) duties, entered into a cooperative agreement with the Northern Region for the inventory of the National Forests...

  7. Erosion of Brassica incana Genetic Resources: Causes and Effects

    NASA Astrophysics Data System (ADS)

    Muscolo, A.; Settineri, G.; Mallamaci, C.; Papalia, T.; Sidari, M.

    2017-07-01

    Brassica incana Ten., possessing a number of useful agronomic traits, represents a precious genetic resource to be used in plant breeding programs to broaden the genetic base in most Brassica crop species. B. incana that grows on limestone cliffs is at risk of genetic erosion for environmental constraints and human activities. We studied the pedological conditions of a Calabrian site where the B. incana grows, and we correlated the soil properties to the physiological and biochemical aspects of B. incana to identify the causes and effects of the genetic erosion of this species. Our results evidenced that physical soil conditions did not affect B. incana growth and nutraceutical properties; conversely, biological soil properties modified its properties. We identified leaf pigments and secondary metabolites that can be used routinely as early warning indicators of plant threat, to evaluate in a short term the dynamic behavior of plants leading to species extinction.

  8. International efforts to protect the global cotton genetic resources

    USDA-ARS?s Scientific Manuscript database

    The genetic resources of cotton are classified into five tetraploid species in the primary gene pool, 20 diploid species in the secondary gene pool, and 25 diploid species in the tertiary gene pool. Unlike several globally important grain crops, the Consultative Group on International Agricultural R...

  9. 75 FR 32187 - National Center for Research Resources; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-07

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special..., National Center for Research Resources, or National Institutes of Health, 6701 Democracy Boulevard, 1...

  10. Idaho National Laboratory Cultural Resource Monitoring Report for FY 2010

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    INL Cultural Resource Management Office

    2010-10-01

    This report describes the cultural resource monitoring activities of the Idaho National Laboratory’s (INL) Cultural Resource Management (CRM) Office during fiscal year 2010 (FY 2010). Throughout the year, thirty-three cultural resource localities were revisited, including somethat were visited more than once, including: two locations with Native American human remains, one of which is a cave, two additional caves, twenty-six prehistoric archaeological sites, two historic stage stations, and Experimental Breeder Reactor-I, which is a designated National Historic Landmark. The resources that were monitored included seventeen that are routinely visited and sixteen that are located in INL project areas. Although impacts weremore » documented at a few locations and one trespassing incident (albeit sans formal charges) was discovered, no significant adverse effects that would threaten the National Register eligibility of any resources were observed. Monitoring also demonstrated that several INL projects generally remain in compliance with recommendations to protect cultural resources.« less

  11. Experiences from the National Institute of Nursing Research: Summer Genetics Institute 2004.

    PubMed

    Whitt, Karen J

    2005-02-01

    The National Institute of Nursing Research (NINR) Summer Genetics Institute (SGI) prepares nurses with training in molecular genetics for use in clinical practice, research, and education. Experiences from the SGI 2004 are recounted. More than 35 genetic experts from National Institutes of Health and surrounding universities in Washington, D.C., provided lecture and laboratory experiences. The lecture portion of the SGI focused on the molecular aspect of genetics and the laboratory component included experiments designed to provide an understanding of genetic approaches for diagnostic and research purposes. The SGI prepares nurses with the genetic foundation to meet the healthcare challenges of the future.

  12. 76 FR 5330 - Bridger-Teton National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ... DEPARTMENT OF AGRICULTURE Forest Service Bridger-Teton National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Bridger-Teton Resource Advisory... be sent to Tracy Hollingshead, Bridger-Teton National Forest, 308 Hwy 189 North, Kemmerer, WY 83101...

  13. 76 FR 2331 - Bridger-Teton National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-13

    ... DEPARTMENT OF AGRICULTURE Forest Service Bridger-Teton National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of Meeting. SUMMARY: The Bridger-Teton Resource Advisory... Hollingshead, Bridger-Teton National Forest, 308 Hwy 189 North, Kemmerer, WY 83101. Comments may also be sent...

  14. 75 FR 61417 - Bridger-Teton National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ... DEPARTMENT OF AGRICULTURE Forest Service Bridger-Teton National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Bridger-Teton Resource Advisory... Hollingshead, Bridger-Teton National Forest, 308 Hwy 189 North, Kemmerer, WY 83101. Comments may also be sent...

  15. Idaho National Laboratory Cultural Resource Monitoring Report for FY 2008

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brenda R. Pace

    2009-01-01

    This report describes the cultural resource monitoring activities of the Idaho National Laboratory’s (INL) Cultural Resource Management (CRM) Office during fiscal year 2008 (FY 2008). Throughout the year, 45 cultural resource localities were revisited including: two locations of heightened Shoshone-Bannock tribal sensitivity, four caves, one butte, twenty-eight prehistoric archaeological sites, three historic homesteads, two historic stage stations, one historic canal construction camp, three historic trails, and Experimental Breeder Reactor-I, which is a designated National Historic Landmark. Several INL project areas were also monitored in FY 2008 to assess project compliance with cultural resource recommendations, confirm the locations of previously recordedmore » cultural resources in relation to project activities, to assess the damage caused by fire-fighting efforts, and to watch for cultural materials during ground disturbing activities. Although impacts were documented at a few locations, no significant adverse effects that would threaten the National Register eligibility of any resource were observed. Monitoring also demonstrated that INL projects generally remain in compliance with recommendations to protect cultural resources« less

  16. Forest resources of the Medicine Bow National Forest

    Treesearch

    Jim Steed

    2008-01-01

    The Interior West Forest Inventory and Analysis (IWFIA) Program of the USDA Forest Service, Rocky Mountain Research Station, as part of our National Forest System cooperative inventories, conducted a forest resource inventory on the Medicine Bow National Forest using a nationally standardized mapped-plot design (for more details see "Inventory methods"...

  17. ETHNOS: A versatile electronic tool for the development and curation of national genetic databases

    PubMed Central

    2010-01-01

    National and ethnic mutation databases (NEMDBs) are emerging online repositories, recording extensive information about the described genetic heterogeneity of an ethnic group or population. These resources facilitate the provision of genetic services and provide a comprehensive list of genomic variations among different populations. As such, they enhance awareness of the various genetic disorders. Here, we describe the features of the ETHNOS software, a simple but versatile tool based on a flat-file database that is specifically designed for the development and curation of NEMDBs. ETHNOS is a freely available software which runs more than half of the NEMDBs currently available. Given the emerging need for NEMDB in genetic testing services and the fact that ETHNOS is the only off-the-shelf software available for NEMDB development and curation, its adoption in subsequent NEMDB development would contribute towards data content uniformity, unlike the diverse contents and quality of the available gene (locus)-specific databases. Finally, we allude to the potential applications of NEMDBs, not only as worldwide central allele frequency repositories, but also, and most importantly, as data warehouses of individual-level genomic data, hence allowing for a comprehensive ethnicity-specific documentation of genomic variation. PMID:20650823

  18. ETHNOS : A versatile electronic tool for the development and curation of national genetic databases.

    PubMed

    van Baal, Sjozef; Zlotogora, Joël; Lagoumintzis, George; Gkantouna, Vassiliki; Tzimas, Ioannis; Poulas, Konstantinos; Tsakalidis, Athanassios; Romeo, Giovanni; Patrinos, George P

    2010-06-01

    National and ethnic mutation databases (NEMDBs) are emerging online repositories, recording extensive information about the described genetic heterogeneity of an ethnic group or population. These resources facilitate the provision of genetic services and provide a comprehensive list of genomic variations among different populations. As such, they enhance awareness of the various genetic disorders. Here, we describe the features of the ETHNOS software, a simple but versatile tool based on a flat-file database that is specifically designed for the development and curation of NEMDBs. ETHNOS is a freely available software which runs more than half of the NEMDBs currently available. Given the emerging need for NEMDB in genetic testing services and the fact that ETHNOS is the only off-the-shelf software available for NEMDB development and curation, its adoption in subsequent NEMDB development would contribute towards data content uniformity, unlike the diverse contents and quality of the available gene (locus)-specific databases. Finally, we allude to the potential applications of NEMDBs, not only as worldwide central allele frequency repositories, but also, and most importantly, as data warehouses of individual-level genomic data, hence allowing for a comprehensive ethnicity-specific documentation of genomic variation.

  19. Map of National Aquatic Resource Surveys Sampling Locations

    EPA Pesticide Factsheets

    This map displays all of the lakes, rivers and streams, wetlands, and coastal waters sampled by the National Aquatic Resource Surveys, a collaborative EPA program that assesses the condition of the nation's waters using statistical designs.

  20. Forest resources of the Idaho Panhandle National Forest

    Treesearch

    Joshua C. Holte

    2012-01-01

    The Interior West Forest Inventory and Analysis (IWFIA) Program of the USDA Forest Service, Rocky Mountain Research Station, as part of our National Forest System cooperative inventories, conducted a forest resource inventory on the Idaho Panhandle National Forest (IPNF) using a nationally standardized mapped-plot design (for more details see "The inventory...

  1. Forest resources of the Nez Perce National Forest

    Treesearch

    Michele Disney

    2010-01-01

    As part of a National Forest System cooperative inventory, the Interior West Forest Inventory and Analysis (IWFIA) Program of the USDA Forest Service conducted a forest resource inventory on the Nez Perce National Forest using a nationally standardized mapped-plot design (for more details see the section "Inventory methods"). This report presents highlights...

  2. Forest resources of the Santa Fe National Forest

    Treesearch

    Dana Lambert

    2004-01-01

    The Interior West Forest Inventory and Analysis (IWFIA) program of the USDA Forest Service, Rocky Mountain Research Station, as part of its national Forest Inventory and Analysis (FIA) duties, conducted forest resource inventories of the Southwestern Region (Region 3) National Forests. This report presents highlights of the Santa Fe National Forest 1998...

  3. Forest resources of the Black Hills National Forest

    Treesearch

    Larry T. DeBlander

    2002-01-01

    The Interior West Forest Inventory and Analysis (IWFIA) Program of the USDA Forest Service, Rocky Mountain Research Station, as part of our National Forest System cooperative inventories, conducted a forest resource inventory on the Black Hills National Forest using a nationally standardized mapped-plot design (for more details see section "How was the inventory...

  4. 75 FR 57972 - National Center for Research Resources; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special..., Scientific Review Officer, Office of Review, National Center for Research Resources, Bethesda, MD 20892, 301...

  5. The conservation of forest genetic resources: case histories from Canada, Mexico, and the United States

    Treesearch

    F. Thomas Ledig; J. Jesús Vargas-Hernández; Kurt H. Johnsen

    1998-01-01

    The genetic codes of living organisms are natural resources no less than soil, air, and water. Genetic resources-from nucleotide sequences in DNA to selected genotypes, populations, and species-are the raw material in forestry: for breeders, for the forest manager who produces an economic crop, for society that reaps the environmental benefits provided by forests, and...

  6. 77 FR 33229 - Notice of Proposed Information Collection: Comment Request; National Resource Network

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-05

    ... Information Collection: Comment Request; National Resource Network AGENCY: Office of the Assistant Secretary... information: Title of Proposal: National Resource Network. OMB Control Number, if applicable: None... and reporting information related to the proposed National Resource Network. The U.S. Department of...

  7. Integration of population genetic structure and plant response to climate change: sustaining genetic resources through evaluation of projected threats

    Treesearch

    Bryce A. Richardson; Marcus V. Warwell; Mee-Sook Kim; Ned B. Klopfenstein; Geral I. McDonald

    2010-01-01

    To assess threats or predict responses to disturbances, or both, it is essential to recognize and characterize the population structures of forest species in relation to changing environments. Appropriate management of these genetic resources in the future will require (1) understanding the existing genetic diversity/variation and population structure of forest trees...

  8. Genetics Home Reference: citrullinemia

    MedlinePlus

    ... Type II MalaCards: citrullinemia, classic Orphanet: Citrullinemia Screening, Technology, and Research in Genetics Virginia Department of Health (PDF) Patient Support and Advocacy Resources (5 links) Children Living with Inherited Metabolic Diseases (CLIMB) (UK) National ...

  9. Dynamic conservation of forest genetic resources in 33 European countries.

    PubMed

    Lefèvre, François; Koskela, Jarkko; Hubert, Jason; Kraigher, Hojka; Longauer, Roman; Olrik, Ditte C; Schüler, Silvio; Bozzano, Michele; Alizoti, Paraskevi; Bakys, Remigijus; Baldwin, Cathleen; Ballian, Dalibor; Black-Samuelsson, Sanna; Bednarova, Dagmar; Bordács, Sándor; Collin, Eric; de Cuyper, Bart; de Vries, Sven M G; Eysteinsson, Thröstur; Frýdl, Josef; Haverkamp, Michaela; Ivankovic, Mladen; Konrad, Heino; Koziol, Czesław; Maaten, Tiit; Notivol Paino, Eduardo; Oztürk, Hikmet; Pandeva, Ivanova Denitsa; Parnuta, Gheorghe; Pilipovič, Andrej; Postolache, Dragos; Ryan, Cathal; Steffenrem, Arne; Varela, Maria Carolina; Vessella, Federico; Volosyanchuk, Roman T; Westergren, Marjana; Wolter, Frank; Yrjänä, Leena; Zariŋa, Inga

    2013-04-01

    Dynamic conservation of forest genetic resources (FGR) means maintaining the genetic diversity of trees within an evolutionary process and allowing generation turnover in the forest. We assessed the network of forests areas managed for the dynamic conservation of FGR (conservation units) across Europe (33 countries). On the basis of information available in the European Information System on FGR (EUFGIS Portal), species distribution maps, and environmental stratification of the continent, we developed ecogeographic indicators, a marginality index, and demographic indicators to assess and monitor forest conservation efforts. The pan-European network has 1967 conservation units, 2737 populations of target trees, and 86 species of target trees. We detected a poor coincidence between FGR conservation and other biodiversity conservation objectives within this network. We identified 2 complementary strategies: a species-oriented strategy in which national conservation networks are specifically designed for key target species and a site-oriented strategy in which multiple-target units include so-called secondary species conserved within a few sites. The network is highly unbalanced in terms of species representation, and 7 key target species are conserved in 60% of the conservation units. We performed specific gap analyses for 11 tree species, including assessment of ecogeographic, demographic, and genetic criteria. For each species, we identified gaps, particularly in the marginal parts of their distribution range, and found multiple redundant conservation units in other areas. The Mediterranean forests and to a lesser extent the boreal forests are underrepresented. Monitoring the conservation efficiency of each unit remains challenging; however, <2% of the conserved populations seem to be at risk of extinction. On the basis of our results, we recommend combining species-oriented and site-oriented strategies. © 2012 Society for Conservation Biology.

  10. National Plant Germplasm System: Critical Role of Customer Service

    USDA-ARS?s Scientific Manuscript database

    The National Plant Germplasm System (NPGS) conserves plant genetic resources, not only for use by future generations, but for immediate use by scientists and educators around the world. With a great deal of interaction between genebank curators and users of plant genetic resources, customer service...

  11. Competences, education and support for new roles in cancer genetics services: outcomes from the cancer genetics pilot projects.

    PubMed

    Bennett, Catherine; Burton, Hilary; Farndon, Peter

    2007-01-01

    In 2004 the Department of Health in collaboration with Macmillan Cancer Support set up service development projects to pilot the integration of genetics in mainstream medicine in the area of cancer genetics.In developing these services, new roles and responsibilities were devised that required supporting programmes of education and training. The NHS National Genetics Education and Development Centre has worked with the projects to draw together their experience in these aspects. New roles include the Cancer Family Nurse Specialist, in which a nurse working in a cancer setting was trained to identify and manage genetic or family history concerns, and the Genetic Risk Assessment Practitioner--a small team of practitioners working within a secondary care setting to deliver a standardised risk assessment pathway. Existing roles were also adapted for a different setting, in particular the use of genetic counsellors working in a community ethnic minority setting. These practitioners undertook a range of clinical activities that can be mapped directly to the 'UK National Workforce Competences for Genetics in Clinical Practice for Non-genetics Healthcare Staff' framework developed by Skills for Health and the NHS National Genetics Education and Development Centre (2007; draft competence framework). The main differences between the various roles were in the ordering of genetic tests and the provision of advice on invasive preventive options such as mastectomy. Those involved in service development also needed to develop competences in project management, business skills, audit and evaluation, working with users, general management (personnel, multi-agency work and marketing), educational supervision, IT, public and professional outreach, and research. Important resources to support the development of new roles and competences included pathways and guidelines, a formal statement of competences, a recognised syllabus, appropriate and timely courses, the availability of a

  12. Forest resources of Mississippi’s national forests, 2006

    Treesearch

    Sonja N. Oswalt

    2011-01-01

    This bulletin describes forest resource characteristics of Mississippi’s national forests, with emphasis on DeSoto National Forest, following the 2006 survey completed by the U.S. Department of Agriculture Forest Service, Forest Inventory and Analysis program. Mississippi’s national forests comprise > 1 million acres of forest land, or about 7 percent of all forest...

  13. Marketing a national forest: the resource manager's dilemma

    Treesearch

    Howard A. Clonts; Jeffrey R. Hibbert

    1995-01-01

    National Forests throughout the United States are facing critical management decisions regarding optimal resource use amidst strong countervailing pressures for access. Visitors to Talladega National Forest in Alabama were surveyed to develop appropriate marketing strategies. Cluster analysis showed that separate homogeneous user groups exist. This information was...

  14. Ecological genetics at the USGS National Wetlands Research Center

    USGS Publications Warehouse

    Travis, Steven

    2006-01-01

    The Ecological Genetics Program at the USGS National Wetlands Research Center (NWRC) employs state-of-the-art DNA fingerprinting technologies in characterizing critical management aspects of the population biology of species of concern (fig. 1). The overarching themes of this program have been (1) the critical role that genetic diversity plays in maintaining population viability and (2) how management strategies might incorporate genetic information in preventing the decline of desirable species or in controlling the spread of invasive species.

  15. Forest resources of the Umatilla National Forest.

    Treesearch

    Glenn A. Christensen; Paul Dunham; David C. Powell; Bruce. Hiserote

    2007-01-01

    Current resource statistics for the Umatilla National Forest, based on two separate inventories conducted in 1993–96 and in 1997–2002, are presented in this report. Currently on the Umatilla National Forest, 89 percent of the land area is classified as forest land. The predominant forest type is grand fir (26 percent of forested acres) followed by the interior Douglas-...

  16. Role of genomics in promoting the utilization of plant genetic resources in genebanks

    PubMed Central

    Wambugu, Peterson W; Ndjiondjop, Marie-Noelle

    2018-01-01

    Abstract Global efforts have seen the world’s plant genetic resources (PGRs) conserved in about 1625 germ plasm repositories. Utility of these resources is important in increasing the resilience and productivity of agricultural production systems. However, despite their importance, utility of these resources has been poor. This article reviews the real and potential application of the current advances in genomic technologies in improving the utilization of these resources. The actual and potential application of these genomic approaches in plant identification, phylogenetic analysis, analysing the genetic value of germ plasm, facilitating germ plasm selection in genebanks as well as instilling confidence in international germ plasm exchange system is discussed. We note that if genebanks are to benefit from this genomic revolution, there is need for fundamental changes in the way genebanks are managed, perceived, organized and funded. Increased collaboration between genebank managers and the user community is also recommended PMID:29688255

  17. History of the National Aquatic Resource Surveys

    EPA Pesticide Factsheets

    Under the Clean Water Act (CWA), the U.S. Environmental Protection Agency must periodically report on the condition of the nation's water resources by summarizing water quality information provided by the states.

  18. 77 FR 48496 - Okanogan and Wenatchee National Forests Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-14

    ... DEPARTMENT OF AGRICULTURE Forest Service Okanogan and Wenatchee National Forests Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Wenatchee-Okanogan Resource Advisory Committee will meet on September 13 at the Okanogan-Wenatchee National Forest Headquarters Office...

  19. Applying the National Aquatic Resource Survey Data

    EPA Pesticide Factsheets

    The NARS generate nationally-consistent water quality data across a variety of indicators. States have applied the NARS data to help address local policy questions and to implement changes regarding aquatic resource management.

  20. Background of the National Aquatic Resource Surveys

    EPA Pesticide Factsheets

    The National Aquatic Resource Surveys (NARS) are statistical surveys designed to assess the status of and changes in quality of the nation’s coastal waters, lakes and reservoirs, rivers and streams, and wetlands.

  1. Market organization and animal genetic resource management: a revealed preference analysis of sheep pricing.

    PubMed

    Tindano, K; Moula, N; Leroy, P; Traoré, A; Antoine-Moussiaux, N

    2017-10-01

    Farm animal genetic resources are threatened worldwide. Participation in markets, while representing a crucial way out of poverty for many smallholders, affects genetic management choices with associated sustainability concerns. This paper proposes a contextualized study of the interactions between markets and animal genetic resources management, in the case of sheep markets in Ouagadougou, Burkina Faso. It focusses on the organization of marketing chains and the valuation of genetic characteristics by value chain actors. Marketing chain characterization was tackled through semi-structured interviews with 25 exporters and 15 butchers, both specialized in sheep. Moreover, revealed preference methods were applied to analyse the impact of animals' attributes on market pricing. Data were collected from 338 transactions during three different periods: Eid al-Adha, Christmas and New Year period, and a neutral period. The neutral period is understood as a period not close to any event likely to influence the demand for sheep. The results show that physical characteristics such as live weight, height at withers and coat colour have a strong influence on the animals' prices. Live weight has also had an increasing marginal impact on price. The different markets (local butcher, feasts, export market, sacrifices) represent distinct demands for genetic characteristics, entailing interesting consequences for animal genetic resource management. Any breeding programme should therefore take this diversity into account to allow this sector to contribute better to a sustainable development of the country.

  2. Genetic algorithm parameters tuning for resource-constrained project scheduling problem

    NASA Astrophysics Data System (ADS)

    Tian, Xingke; Yuan, Shengrui

    2018-04-01

    Project Scheduling Problem (RCPSP) is a kind of important scheduling problem. To achieve a certain optimal goal such as the shortest duration, the smallest cost, the resource balance and so on, it is required to arrange the start and finish of all tasks under the condition of satisfying project timing constraints and resource constraints. In theory, the problem belongs to the NP-hard problem, and the model is abundant. Many combinatorial optimization problems are special cases of RCPSP, such as job shop scheduling, flow shop scheduling and so on. At present, the genetic algorithm (GA) has been used to deal with the classical RCPSP problem and achieved remarkable results. Vast scholars have also studied the improved genetic algorithm for the RCPSP problem, which makes it to solve the RCPSP problem more efficiently and accurately. However, for the selection of the main parameters of the genetic algorithm, there is no parameter optimization in these studies. Generally, we used the empirical method, but it cannot ensure to meet the optimal parameters. In this paper, the problem was carried out, which is the blind selection of parameters in the process of solving the RCPSP problem. We made sampling analysis, the establishment of proxy model and ultimately solved the optimal parameters.

  3. Assessing the Nation's Brackish Groundwater Resources

    NASA Astrophysics Data System (ADS)

    Stanton, J.; Anning, D. W.; Moore, R. B.; McMahon, P. B.; Bohlke, J. K.; McGuire, V. L.

    2014-12-01

    Declines in the amount of groundwater in storage as a result of groundwater development have led to concerns about the future availability of freshwater to meet drinking-water, agricultural, industrial, and environmental needs. Industry and public drinking-water suppliers have increasingly turned to nontraditional groundwater sources, such as moderately saline (brackish) groundwater, to supplement or replace the use of freshwater. Despite the growing demand for alternative water sources, a significant potential nontraditional water resource, brackish groundwater, was last assessed almost 50 years ago. The recently (2013) initiated USGS National Brackish Groundwater Assessment, which is part of the National Water Census, will provide an updated systematic national assessment of the distribution of significant brackish groundwater resources and critical information about the hydrogeologic and chemical characterization of brackish aquifers. As part of this study, updated national-scale maps of total dissolved-solids concentrations and chemical water types will be created using data from about 400,000 sites that have been compiled from over 30 national, regional, and state sources. However, available data are biased toward freshwater and shallow systems. Preliminary analysis indicates that about 75 percent of the dissolved-solids concentrations are from freshwater aquifers, and more than 80 percent represent depths less than 500 feet below land surface. Several techniques are used to extend the information contained in the compiled data. For about half of the sites, dissolved-solids concentration was estimated from specific conductance using statistical relations. In addition, for areas where chemical data are not available, regression models are being developed to predict the occurrence of brackish groundwater based on geospatial data such as geology and other variables that are correlated to dissolved-solids concentrations.

  4. 76 FR 8378 - National Park Service Alaska Region's Subsistence Resource Commission (SRC) Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-14

    ... DEPARTMENT OF THE INTERIOR National Park Service [NPS-AKR-DENA] [9924-PYS] National Park Service Alaska Region's Subsistence Resource Commission (SRC) Program AGENCY: National Park Service, Interior. ACTION: Notice of public meeting for the National Park Service Alaska Region's Subsistence Resource...

  5. Partners in the National Aquatic Resource Surveys

    EPA Pesticide Factsheets

    EPA is working with state, tribal, and other federal agencies to implement the National Aquatic Resource Surveys (NARS). States and tribes participate in these surveys through their Clean Water Act Section 106 Monitoring Initiative grants.

  6. The United Nations Framework Classification for World Petroleum Resources

    USGS Publications Warehouse

    Ahlbrandt, T.S.; Blystad, P.; Young, E.D.; Slavov, S.; Heiberg, S.

    2003-01-01

    The United Nations has developed an international framework classification for solid fuels and minerals (UNFC). This is now being extended to petroleum by building on the joint classification of the Society of Petroleum Engineers (SPE), the World Petroleum Congresses (WPC) and the American Association of Petroleum Geologists (AAPG). The UNFC is a 3-dimansional classification. This: Is necessary in order to migrate accounts of resource quantities that are developed on one or two of the axes to the common basis; Provides for more precise reporting and analysis. This is particularly useful in analyses of contingent resources. The characteristics of the SPE/WPC/AAPG classification has been preserved and enhanced to facilitate improved international and national petroleum resource management, corporate business process management and financial reporting. A UN intergovernmental committee responsible for extending the UNFC to extractive energy resources (coal, petroleum and uranium) will meet in Geneva on October 30th and 31st to review experiences gained and comments received during 2003. A recommended classification will then be delivered for consideration to the United Nations through the Committee on Sustainable Energy of the Economic Commission for Europe (UN ECE).

  7. America's Changing Energy Landscape - USGS National Coal Resources Data System Changes to National Energy Resources Data System.

    NASA Astrophysics Data System (ADS)

    East, J. A., II

    2016-12-01

    The U.S. Geological Survey's (USGS) Eastern Energy Resources Science Center (EERSC) has an ongoing project which has mapped coal chemistry and stratigraphy since 1977. Over the years, the USGS has collected various forms of coal data and archived that data into the National Coal Resources Data System (NCRDS) database. NCRDS is a repository that houses data from the major coal basins in the United States and includes information on location, seam thickness, coal rank, geologic age, geographic region, geologic province, coalfield, and characteristics of the coal or lithology for that data point. These data points can be linked to the US Coal Quality Database (COALQUAL) to include ultimate, proximate, major, minor and trace-element data. Although coal is an inexpensive energy provider, the United States has shifted away from coal usage recently and branched out into other forms of non-renewable and renewable energy because of environmental concerns. NCRDS's primary method of data capture has been USGS field work coupled with cooperative agreements with state geological agencies and universities doing coal-related research. These agreements are on competitive five-year cycles that have evolved into larger scope research efforts including solid fuel resources such as coal-bed methane, shale gas and oil. Recently these efforts have expanded to include environmental impacts of the use of fossil fuels, which has allowed the USGS to enter into agreements with states for the Geologic CO2 Storage Resources Assessment as required by the Energy Independence and Security Act. In 2016 they expanded into research areas to include geothermal, conventional and unconventional oil and gas. The NCRDS and COALQUAL databases are now online for the public to use, and are in the process of being updated to include new data for other energy resources. Along with this expansion of scope, the database name will change to the National Energy Resources Data System (NERDS) in FY 2017.

  8. Deaf-Blindness: National Organizations and Resources. Reference Circular No. 93-1.

    ERIC Educational Resources Information Center

    Library of Congress, Washington, DC. National Library Service for the Blind and Physically Handicapped.

    This circular lists national organizations and print and audiovisual resources on areas of service to persons with deaf blindness, including rehabilitation, education, information and referral, recreation, and sources for adaptive devices and products. Section I is an alphabetical list of 40 national organizations and resources, including…

  9. Genetics Home Reference: isovaleric acidemia

    MedlinePlus

    ... Consortium of Metabolic Programs Orphanet: Isovaleric acidemia Screening, Technology, and Research in Genetics Virginia Department of Health (PDF) Patient Support and Advocacy Resources (4 links) CLIMB (Children Living With Inherited Metabolic Diseases) (UK) National Organization ...

  10. Genetics Home Reference: propionic acidemia

    MedlinePlus

    ... Consortium of Metabolic Programs Orphanet: Propionic acidemia Screening, Technology, and Research in Genetics Virginia Department of Health (PDF) Patient Support and Advocacy Resources (6 links) CLIMB (Children Living With Inherited Metabolic Diseases) (UK) National Organization ...

  11. A WebGIS platform for the monitoring of Farm Animal Genetic Resources (GENMON)

    PubMed Central

    Flury, Christine; Matasci, Giona; Joerin, Florent; Widmer, Ivo; Joost, Stéphane

    2017-01-01

    Background In 2007, the Food and Agriculture Organization of the United Nations (FAO) initiated the Global plan of action for Farm Animal Genetic Resources (FAnGR). The main goal of this plan is to reduce further loss of genetic diversity in farm animals, so as to protect and promote the diversity of farm animal resources. An important step to reach this goal is to monitor and prioritize endangered breeds in the context of conservation programs. Methodology/Web portal implementation The GENMON WebGIS platform is able to monitor FAnGR and to evaluate the degree of endangerment of livestock breeds. The system takes into account pedigree and introgression information, the geographical concentration of animals, the cryo-conservation plan and the sustainability of breeding activities based on socio-economic data as well as present and future land use conditions. A multi-criteria decision tool supports the aggregation of the multi-thematic indices mentioned above using the MACBETH method, which is based on a weighted average using satisfaction thresholds. GENMON is a monitoring tool to reach subjective decisions made by a government agency. It relies on open source software and is available at http://lasigsrv2.epfl.ch/genmon-ch. Results/Significance GENMON allows users to upload pedigree-information (animal ID, parents, birthdate, sex, location and introgression) from a specific livestock breed and to define species and/or region-specific weighting parameters and thresholds. The program then completes a pedigree analysis and derives several indices that are used to calculate an integrated score of conservation prioritization for the breeds under investigation. The score can be visualized on a geographic map and allows a fast, intuitive and regional identification of breeds in danger. Appropriate conservation actions and breeding programs can thus be undertaken in order to promote the recovery of the genetic diversity in livestock breeds in need. The use of the platform

  12. A WebGIS platform for the monitoring of Farm Animal Genetic Resources (GENMON).

    PubMed

    Duruz, Solange; Flury, Christine; Matasci, Giona; Joerin, Florent; Widmer, Ivo; Joost, Stéphane

    2017-01-01

    In 2007, the Food and Agriculture Organization of the United Nations (FAO) initiated the Global plan of action for Farm Animal Genetic Resources (FAnGR). The main goal of this plan is to reduce further loss of genetic diversity in farm animals, so as to protect and promote the diversity of farm animal resources. An important step to reach this goal is to monitor and prioritize endangered breeds in the context of conservation programs. The GENMON WebGIS platform is able to monitor FAnGR and to evaluate the degree of endangerment of livestock breeds. The system takes into account pedigree and introgression information, the geographical concentration of animals, the cryo-conservation plan and the sustainability of breeding activities based on socio-economic data as well as present and future land use conditions. A multi-criteria decision tool supports the aggregation of the multi-thematic indices mentioned above using the MACBETH method, which is based on a weighted average using satisfaction thresholds. GENMON is a monitoring tool to reach subjective decisions made by a government agency. It relies on open source software and is available at http://lasigsrv2.epfl.ch/genmon-ch. GENMON allows users to upload pedigree-information (animal ID, parents, birthdate, sex, location and introgression) from a specific livestock breed and to define species and/or region-specific weighting parameters and thresholds. The program then completes a pedigree analysis and derives several indices that are used to calculate an integrated score of conservation prioritization for the breeds under investigation. The score can be visualized on a geographic map and allows a fast, intuitive and regional identification of breeds in danger. Appropriate conservation actions and breeding programs can thus be undertaken in order to promote the recovery of the genetic diversity in livestock breeds in need. The use of the platform is illustrated by means of an example based on three local livestock

  13. National ITS Architecture and Standards Resource Guide

    DOT National Transportation Integrated Search

    1998-09-01

    The Transportation Equity Act for the 21st Century (TEA-21) encourages the use of the National ITS Architecture and the adoption of ITS standards and protocols. This guide provides field personnel with guidance and resources necessary for implementin...

  14. Understanding Resource Nationalism in the 21st Century

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hughes, Llewelyn; Kreyling, Sean J.

    2010-07-26

    Resource nationalism in oil-importing states appears on the rise. Oil price volatility underpinned by demand growth has led China, India and others to increase state support for national-flag firms in order to increase the state’s energy self-sufficiency. Both Chinese and Indian National Oil Companies (NOCs) have made energy investments worldwide, including in Sudan and Iran. Long-standing oil importers such as the United States and Japan have reenergized policies designed to increase domestic production of crude and crude substitutes, or have subsidized national-flag firms, in the name of energy independence.

  15. Two approaches for incorporating climate change into natural resource management planning at Wind Cave National Park

    USGS Publications Warehouse

    Symstad, Amy J.; Long, Andrew J.; Stamm, John; King, David A.; Bachelet, Dominque M.; Norton, Parker A.

    2014-01-01

    Wind Cave National Park (WICA) protects one of the world’s longest caves, has large amounts of high quality, native vegetation, and hosts a genetically important bison herd. The park’s relatively small size and unique purpose within its landscape requires hands-on management of these and other natural resources, all of which are interconnected. Anthropogenic climate change presents an added challenge to WICA natural resource management because it is characterized by large uncertainties, many of which are beyond the control of park and National Park Service (NPS) staff. When uncertainty is high and control of this uncertainty low, scenario planning is an appropriate tool for determining future actions. In 2009, members of the NPS obtained formal training in the use of scenario planning in order to evaluate it as a tool for incorporating climate change into NPS natural resource management planning. WICA served as one of two case studies used in this training exercise. Although participants in the training exercise agreed that the scenario planning process showed promise for its intended purpose, they were concerned that the process lacked the scientific rigor necessary to defend the management implications derived from it in the face of public scrutiny. This report addresses this concern and others by (1) providing a thorough description of the process of the 2009 scenario planning exercise, as well as its results and management implications for WICA; (2) presenting the results of a follow-up, scientific study that quantitatively simulated responses of WICA’s hydrological and ecological systems to specific climate projections; (3) placing these climate projections and the general climate scenarios used in the scenario planning exercise in the broader context of available climate projections; and (4) comparing the natural resource management implications derived from the two approaches. Wind Cave National Park (WICA) protects one of the world’s longest caves

  16. Rice diversity panels available through the genetic stocks oryza collection

    USDA-ARS?s Scientific Manuscript database

    The Genetic Stocks Oryza (GSOR) Collection was established in 2004 at the USDA-ARS, Dale Bumpers National Rice Research Center (DBNRRC) located in Stuttgart, AR. The mission of GSOR is to provide unique genetic resources to the rice research community for genetic and genomics related research. GSOR ...

  17. Forest resources of South Carolina's national forests, 2001

    Treesearch

    Sonja N. Oswalt

    2005-01-01

    This bulletin describes forest resources of the Francis Marion and Sumter National Forests in the State of South Carolina. It is based on sampling from the eighth forest inventory conducted by the U.S. Department of Agriculture Forest Service, Southern Research Station, Forest Inventory and Analysis Research Work Unit. Findings suggest that South Carolina’s national...

  18. Conflict Bear Translocation: Investigating Population Genetics and Fate of Bear Translocation in Dachigam National Park, Jammu and Kashmir, India

    PubMed Central

    Mukesh; Sharma, Lalit Kumar; Charoo, Samina Amin; Sathyakumar, Sambandam

    2015-01-01

    The Asiatic black bear population in Dachigam landscape, Jammu and Kashmir is well recognized as one of the highest density bear populations in India. Increasing incidences of bear-human interactions and the resultant retaliatory killings by locals have become a serious threat to the survivorship of black bears in the Dachigam landscape. The Department of Wildlife Protection in Jammu and Kashmir has been translocating bears involved in conflicts, henceforth ‘conflict bears’ from different sites in Dachigam landscape to Dachigam National Park as a flagship activity to mitigate conflicts. We undertook this study to investigate the population genetics and the fate of bear translocation in Dachigam National Park. We identified 109 unique genotypes in an area of ca. 650 km2 and observed bear population under panmixia that showed sound genetic variability. Molecular tracking of translocated bears revealed that mostly bears (7 out of 11 bears) returned to their capture sites, possibly due to homing instincts or habituation to the high quality food available in agricultural croplands and orchards, while only four bears remained in Dachigam National Park after translocation. Results indicated that translocation success was most likely to be season dependent as bears translocated during spring and late autumn returned to their capture sites, perhaps due to the scarcity of food inside Dachigam National Park while bears translocated in summer remained in Dachigam National Park due to availability of surplus food resources. Thus, the current management practices of translocating conflict bears, without taking into account spatio-temporal variability of food resources in Dachigam landscape seemed to be ineffective in mitigating conflicts on a long-term basis. However, the study highlighted the importance of molecular tracking of bears to understand their movement patterns and socio-biology in tough terrains like Dachigam landscape. PMID:26267280

  19. Conflict bear translocation: investigating population genetics and fate of bear translocation in Dachigam National Park, Jammu and Kashmir, India.

    PubMed

    Mukesh; Sharma, Lalit Kumar; Charoo, Samina Amin; Sathyakumar, Sambandam

    2015-01-01

    The Asiatic black bear population in Dachigam landscape, Jammu and Kashmir is well recognized as one of the highest density bear populations in India. Increasing incidences of bear-human interactions and the resultant retaliatory killings by locals have become a serious threat to the survivorship of black bears in the Dachigam landscape. The Department of Wildlife Protection in Jammu and Kashmir has been translocating bears involved in conflicts, henceforth 'conflict bears' from different sites in Dachigam landscape to Dachigam National Park as a flagship activity to mitigate conflicts. We undertook this study to investigate the population genetics and the fate of bear translocation in Dachigam National Park. We identified 109 unique genotypes in an area of ca. 650 km2 and observed bear population under panmixia that showed sound genetic variability. Molecular tracking of translocated bears revealed that mostly bears (7 out of 11 bears) returned to their capture sites, possibly due to homing instincts or habituation to the high quality food available in agricultural croplands and orchards, while only four bears remained in Dachigam National Park after translocation. Results indicated that translocation success was most likely to be season dependent as bears translocated during spring and late autumn returned to their capture sites, perhaps due to the scarcity of food inside Dachigam National Park while bears translocated in summer remained in Dachigam National Park due to availability of surplus food resources. Thus, the current management practices of translocating conflict bears, without taking into account spatio-temporal variability of food resources in Dachigam landscape seemed to be ineffective in mitigating conflicts on a long-term basis. However, the study highlighted the importance of molecular tracking of bears to understand their movement patterns and socio-biology in tough terrains like Dachigam landscape.

  20. Subregional resource allocations in the National Health Service.

    PubMed Central

    Snaith, A H

    1978-01-01

    The Resource Allocation Working Party in its report Sharing Resources for Health in England proposes a formula for the identification of both regional and district financial targets (Department of Health and Social Security, 1976). In this paper it is argued that the national formula is not a valid instrument for the latter purpose. Furthermore, research into medical needs and outcomes will not be adequate to bring about real changes in resource distribution at local levels unless it is recognised that the health authorities can meet needs in different ways and that a change in resource management from institutional to service budgeting is required. PMID:262582

  1. 76 FR 14898 - Daniel Boone National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-18

    ... DEPARTMENT OF AGRICULTURE Forest Service Daniel Boone National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Daniel Boone National Forest... basement floor. Written comments should be sent to Kimberly Morgan, Daniel Boone National Forest, 1700...

  2. Population Genetic Structure of Glycyrrhiza inflata B. (Fabaceae) Is Shaped by Habitat Fragmentation, Water Resources and Biological Characteristics.

    PubMed

    Yang, Lulu; Chen, Jianjun; Hu, Weiming; Yang, Tianshun; Zhang, Yanjun; Yukiyoshi, Tamura; Zhou, Yanyang; Wang, Ying

    2016-01-01

    Habitat fragmentation, water resources and biological characteristics are important factors that shape the genetic structure and geographical distribution of desert plants. Analysis of the relationships between these factors and population genetic variation should help to determine the evolutionary potential and conservation strategies for genetic resources for desert plant populations. As a traditional Chinese herb, Glycyrrhiza inflata B. (Fabaceae) is restricted to the fragmented desert habitat in China and has undergone a dramatic decline due to long-term over-excavation. Determining the genetic structure of the G. inflata population and identifying a core collection could help with the development of strategies to conserve this species. We investigated the genetic variation of 25 G. inflata populations based on microsatellite markers. A high level of population genetic divergence (FST = 0.257), population bottlenecks, reduced gene flow and moderate genetic variation (HE = 0.383) were detected. The genetic distances between the populations significantly correlated with the geographical distances, and this suggests that habitat fragmentation has driven a special genetic structure of G. inflata in China through isolation by distance. STRUCTURE analysis showed that G. inflata populations were structured into three clusters and that the populations belonged to multiple water systems, which suggests that water resources were related to the genetic structure of G. inflata. In addition, the biological characteristics of the perennial species G. inflata, such as its long-lived seeds, asexual reproduction, and oasis ecology, may be related to its resistance to habitat fragmentation. A core collection of G. inflata, that included 57 accessions was further identified, which captured the main allelic diversity of G. inflata. Recent habitat fragmentation has accelerated genetic divergence. The population genetic structure of G. inflata has been shaped by habitat

  3. The forest resources of the Ottawa National Forest, 1993.

    Treesearch

    Earl C. Leatherberry; James L. Meunier

    1997-01-01

    The inventory of the forest resources of the Ottawa National Forest reports 967.0 thousand acres of land, of which 908.6 thousand acres are forested. This bulletin presents an analysis of forest resources focusing on change in tree species composition, timber volume, growth, removals, and mortality.

  4. Status and trends of the nation's biological resources

    USGS Publications Warehouse

    Mac, Michael J.; Opler, Paul A.; Puckett Haecker, Catherine E.; Doran, Peter D.

    1998-01-01

    This report is a comprehensive summary of the status and trends of our nation’s biological resources. The report describes the major processes and factors affecting biological resources, and it treats regional status and trends. Authors of the chapters and boxes in this two-volume report were drawn from federal and state agencies, universities, and private organizations, reflecting the U.S. Geological Survey’s national partnership approach to providing comprehensive, reliable information about our biological resources. Following scientific tradition, each chapter and box was peer-reviewed by anonymous scientific reviewers.

  5. Resources for Genetic and Genomic Analysis of Emerging Pathogen Acinetobacter baumannii

    PubMed Central

    Ramage, Elizabeth; Weiss, Eli J.; Radey, Matthew; Hayden, Hillary S.; Held, Kiara G.; Huse, Holly K.; Zurawski, Daniel V.; Brittnacher, Mitchell J.; Manoil, Colin

    2015-01-01

    ABSTRACT Acinetobacter baumannii is a Gram-negative bacterial pathogen notorious for causing serious nosocomial infections that resist antibiotic therapy. Research to identify factors responsible for the pathogen's success has been limited by the resources available for genome-scale experimental studies. This report describes the development of several such resources for A. baumannii strain AB5075, a recently characterized wound isolate that is multidrug resistant and displays robust virulence in animal models. We report the completion and annotation of the genome sequence, the construction of a comprehensive ordered transposon mutant library, the extension of high-coverage transposon mutant pool sequencing (Tn-seq) to the strain, and the identification of the genes essential for growth on nutrient-rich agar. These resources should facilitate large-scale genetic analysis of virulence, resistance, and other clinically relevant traits that make A. baumannii a formidable public health threat. IMPORTANCE Acinetobacter baumannii is one of six bacterial pathogens primarily responsible for antibiotic-resistant infections that have become the scourge of health care facilities worldwide. Eliminating such infections requires a deeper understanding of the factors that enable the pathogen to persist in hospital environments, establish infections, and resist antibiotics. We present a set of resources that should accelerate genome-scale genetic characterization of these traits for a reference isolate of A. baumannii that is highly virulent and representative of current outbreak strains. PMID:25845845

  6. 78 FR 64532 - Gates of the Arctic National Park Subsistence Resource Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-29

    ....LS0000] Gates of the Arctic National Park Subsistence Resource Commission Meeting AGENCY: National Park... Arctic National Park Subsistence Resource Commission (SRC) will hold a meeting to develop and continue... Conservation Act, Public Law 96-487. DATES: The Gates of the Arctic National Park SRC will meet from 9:00 a.m...

  7. 75 FR 64692 - Daniel Boone National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-20

    ... DEPARTMENT OF AGRICULTURE Forest Service Daniel Boone National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Daniel Boone National Forest... Boone National Forest, 1700 Bypass Road, Winchester, KY 40391. Comments may also be sent via email to...

  8. Timber resource statistics for timberland outside National Forests in eastern Oregon.

    Treesearch

    Neil McKay; Gary J. Lettman; Mary A. Mei

    1994-01-01

    This report summarizes a 1992 timber resource inventory Of timberland outside National Forests in eastern Oregon. The report presents statistical tables of timberland area, timber volume, growth, mortality, and harvest. It also displays tables of revised 1986-87 timber resource statistics for timberland outside National Forests; the 1992 and 1986-87 tables may be...

  9. The Iranian Human Mutation Gene Bank: a data and sample resource for worldwide collaborative genetics research.

    PubMed

    Najmabadi, Hossein; Neishabury, Maryam; Sahebjam, Farhad; Kahrizi, Kimia; Shafaghati, Yousef; Nikzat, Nushin; Jalalvand, Maryam; Aminy, Farahnaz; Hashemi, Susan Bany; Moghimi, Babak; Noorian, Ali Reza; Jannati, Ali; Mohammadi, Mehrdad; Javan, Khalil

    2003-02-01

    As Human Genome Project exploration continues, the necessity of having a broader spectrum of genomic DNA material from different nationalities to study various aspects of hereditary disease becomes more obvious. The existence of high genetic polymorphism within and between different communities in the world makes it necessary for the gene hunters to investigate many different populations. Iran, a large country with close to 66 million people, is a land of different nationalities, tribes, and religions that offers a highly heterogeneous gene pool to the genetics researcher. The purity of many different races in this country has been highly conserved by geographical borders and by an ancient culture that has always encouraged intrafamilial marriages. All these have created a population that is remarkably heterogeneous yet high in consanguinity rate. During the last five years of investigation we have established a DNA bank, the Iranian Human Mutation Gene Bank (www.IHMGB.com), which contains all genetic diseases studied in Iran that have the Mendelian mode of inheritance. Some of the samples are assigned to common or novel mutations and others belong to patients with clinical profiles associated with particular genetic diseases but undefined mutation. This bank stores samples of DNA from the patient and his/her first-degree relatives together with a comprehensive pedigree and clinical profile for each sample. To facilitate collaboration with other scientists around the world with the same interests, we decided to present our experimental projects online. This DNA bank provides opportunities for us to collaborate with scientists outside Iran. It offers a sample resource to research scientists around the world, at no charge, for the purpose of investigating the various aspects of genetic disorders from prenatal diagnosis to gene structure and function. It is strongly stressed that no commercial benefit is involved in the establishment of this DNA bank and the DNA

  10. Resources for human genetics on the World Wide Web.

    PubMed

    Osborne, L R; Lee, J R; Scherer, S W

    1997-09-01

    A little over a century ago, the HMS Beagle sailed the Pacific Ocean bringing Charles Darwin to the perfect environment in which to piece together his observations forming the theory of evolution. Now, geneticists and laypeople alike surf the equally formidable waters of the internet in search of enlightenment. Here, we attempt to help you navigate towards resources for human genetics by providing maps to three destinations: The Human Genome Project (Box 1), education (Box 2), and human genetic diseases (Box 3). For each, we highlight a few sites that we consider are the most informative and original. A more extensive list containing other useful sites has been compiled and posted on a 'jump site' at: http:/(/)www.cgdn.generes.ca/.

  11. Resource nationalism in Indonesia—Effects of the 2014 mineral export ban

    USGS Publications Warehouse

    Lederer, Graham W.

    2016-09-27

    Resource nationalism encompasses a broad range of political and economic actions taken by Governments to regulate the extraction of natural resources within their borders. Policies such as increased tariffs or export restrictions can have far-reaching economic effects on international trade. As the Governments of several developing countries consider enacting nationalistic policies, an examination of the 2014 mineral export ban in Indonesia provides an instructive example of the possible impacts of resource nationalism. Significant changes in the production and trade of unprocessed (that is, ores and concentrates) and processed (that is, refined metal) aluminum, copper, and nickel before and after the export ban form the basis of this study.The U.S. Geological Survey (USGS) National Minerals Information Center (NMIC) tracks production and trade of mineral commodities between producer and consumer countries. Materials flow studies clarify the effects of an export ban on different mineral commodities by assessing changes in production, processing capacity, and trade. Using extensive data collection and monitoring procedures, the USGS NMIC investigated the effects of resource nationalism on the flow of mineral commodities from Indonesia to the global economy.

  12. 75 FR 57438 - Chippewa National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ... FURTHER INFORMATION CONTACT: Kay K. Getting, Public Affairs Team Leader, Chippewa National Forest... Resource Advisory Committee members on their roles and responsibilities. DATES: The meeting will be held on... following business will be conducted: Overview of the roles and responsbilities of the Chippewa National...

  13. Genetics Home Reference: N-acetylglutamate synthase deficiency

    MedlinePlus

    ... Hyperammonemia due to N-acetylglutamate synthase deficiency Screening, Technology and Research in Genetics Patient Support and Advocacy Resources (4 links) Children Living with Inherited Metabolic Diseases National Organization for ...

  14. HIV/AIDS Information Resources from the National Library of Medicine-STOP

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Templin-Branner, W. and N. Dancy

    2010-06-15

    The HIV/AIDS Information Resources from the National Library of Medicine training is designed specifically for the UNCFSP HBCU Screening, Testing, Outreach, and Prevention (STOP) HIV/AIDS Program project members to provide valuable health information resources from the National Library of Medicine and other reliable sources to increase awareness of the wealth of treatment information and educational materials that are available on the Internet and to improve prevention and treatment education for their clients. These resources will also meet the needs of community-based organizations

  15. Creation of a national resource with linked genealogy and phenotypic data: the Veterans Genealogy Project.

    PubMed

    Cannon-Albright, Lisa A; Dintelman, Sue; Maness, Tim; Backus, Steve; Thomas, Alun; Meyer, Laurence J

    2013-07-01

    Creation of a genealogy of the United States and its ancestral populations is under way. When complete, this US genealogy will be record linked to the National Veteran's Health Administration medical data representing more than 8 million US veterans. Genealogical data are gathered from public sources, primarily the Internet. Record linking using data from relatives is accomplished to integrate multiple data sources and then to link genealogical data to the veteran's demographic data. This resource currently includes genealogy for more than 22 million individuals representing the Intermountain West and the East Coast. The demographic data for more than 40,000 veteran patients using Veterans Hospital Administration services in Utah and Massachusetts have already been record linked. The resource is only in its second year of creation and already represents the largest such combination of genealogy and medical data in the world. The data sources, the creation of the genealogy, record-linking methods and results, proposed genetic analyses, and future directions are discussed.

  16. MOLECULAR GENETIC TOOLS FOR ASSESSING THE STATUS AND VULNERABILITY OF AQUATIC RESOURCES

    EPA Science Inventory

    Development of ecological indicators that efficiently capture the present condition and project future vulnerabilities of biological resources is critical to sound environmental management. For this reason, the ORD's Ecological Research Program is developing genetic methodologies...

  17. 76 FR 6761 - Daniel Boone National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-08

    ... DEPARTMENT OF AGRICULTURE Forest Service Daniel Boone National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Daniel Boone National Forest... National Forest, 1700 Bypass Road, Winchester, KY 40391. Comments may also be sent via e-mail to [email protected

  18. Manuals Used in the National Aquatic Resource Surveys

    EPA Pesticide Factsheets

    Various manuals are used to communicate the methods and guidelines for the National Aquatic Resource Surveys. The Field Operations Manual: outlines the field protocols that crews will utilize to sample sites.

  19. Idaho National Laboratory Cultural Resource Management Annual Report FY 2007

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Julie Braun; Hollie Gilbert; Dino Lowrey

    2008-03-01

    The Idaho National Laboratory (INL) Site is home to vast numbers and a wide variety of important cultural resources representing at least a 13,500-year span of human land use in the region. As a federal agency, the Department of Energy Idaho Operations Office has legal responsibility for the management and protection of those resources and has delegated these responsibilities to its primary contractor, Battelle Energy Alliance (BEA). The BEA professional staff is committed to maintaining a cultural resource management program that accepts these challenges in a manner reflecting the resources’ importance in local, regional, and national history. This annual reportmore » summarizes activities performed by the INL Cultural Resource Management Office (CRMO) staff during fiscal year 2007. This work is diverse, far-reaching and though generally confined to INL cultural resource compliance, also includes a myriad of professional and voluntary community activities. This document is intended to be both informative to internal and external stakeholders, and to serve as a planning tool for future cultural resource management work to be conducted on the INL.« less

  20. Utilization of farm animal genetic resources in a changing agro-ecological environment in the Nordic countries.

    PubMed

    Kantanen, Juha; Løvendahl, Peter; Strandberg, Erling; Eythorsdottir, Emma; Li, Meng-Hua; Kettunen-Præbel, Anne; Berg, Peer; Meuwissen, Theo

    2015-01-01

    Livestock production is the most important component of northern European agriculture and contributes to and will be affected by climate change. Nevertheless, the role of farm animal genetic resources in the adaptation to new agro-ecological conditions and mitigation of animal production's effects on climate change has been inadequately discussed despite there being several important associations between animal genetic resources and climate change issues. The sustainability of animal production systems and future food security require access to a wide diversity of animal genetic resources. There are several genetic questions that should be considered in strategies promoting adaptation to climate change and mitigation of environmental effects of livestock production. For example, it may become important to choose among breeds and even among farm animal species according to their suitability to a future with altered production systems. Some animals with useful phenotypes and genotypes may be more useful than others in the changing environment. Robust animal breeds with the potential to adapt to new agro-ecological conditions and tolerate new diseases will be needed. The key issue in mitigation of harmful greenhouse gas effects induced by livestock production is the reduction of methane (CH4) emissions from ruminants. There are differences in CH4 emissions among breeds and among individual animals within breeds that suggest a potential for improvement in the trait through genetic selection. Characterization of breeds and individuals with modern genomic tools should be applied to identify breeds that have genetically adapted to marginal conditions and to get critical information for breeding and conservation programs for farm animal genetic resources. We conclude that phenotyping and genomic technologies and adoption of new breeding approaches, such as genomic selection introgression, will promote breeding for useful characters in livestock species.

  1. Utilization of farm animal genetic resources in a changing agro-ecological environment in the Nordic countries

    PubMed Central

    Kantanen, Juha; Løvendahl, Peter; Strandberg, Erling; Eythorsdottir, Emma; Li, Meng-Hua; Kettunen-Præbel, Anne; Berg, Peer; Meuwissen, Theo

    2015-01-01

    Livestock production is the most important component of northern European agriculture and contributes to and will be affected by climate change. Nevertheless, the role of farm animal genetic resources in the adaptation to new agro-ecological conditions and mitigation of animal production’s effects on climate change has been inadequately discussed despite there being several important associations between animal genetic resources and climate change issues. The sustainability of animal production systems and future food security require access to a wide diversity of animal genetic resources. There are several genetic questions that should be considered in strategies promoting adaptation to climate change and mitigation of environmental effects of livestock production. For example, it may become important to choose among breeds and even among farm animal species according to their suitability to a future with altered production systems. Some animals with useful phenotypes and genotypes may be more useful than others in the changing environment. Robust animal breeds with the potential to adapt to new agro-ecological conditions and tolerate new diseases will be needed. The key issue in mitigation of harmful greenhouse gas effects induced by livestock production is the reduction of methane (CH4) emissions from ruminants. There are differences in CH4 emissions among breeds and among individual animals within breeds that suggest a potential for improvement in the trait through genetic selection. Characterization of breeds and individuals with modern genomic tools should be applied to identify breeds that have genetically adapted to marginal conditions and to get critical information for breeding and conservation programs for farm animal genetic resources. We conclude that phenotyping and genomic technologies and adoption of new breeding approaches, such as genomic selection introgression, will promote breeding for useful characters in livestock species. PMID:25767477

  2. Inventorying national forest resources...for planning-programing-budgeting system

    Treesearch

    Miles R. Hill; Elliot L. Amidon

    1968-01-01

    New systems for analyzing resource management problems, such as Planning-Programing-Budgeting, will require automated procedures to collect and assemble resource inventory data. A computer - oriented system called Map Information Assembly and Display System developed for this purpose was tested on a National Forest in California. It provided information on eight forest...

  3. Updated United Nations Framework Classification for reserves and resources of extractive industries

    USGS Publications Warehouse

    Ahlbrandt, T.S.; Blaise, J.R.; Blystad, P.; Kelter, D.; Gabrielyants, G.; Heiberg, S.; Martinez, A.; Ross, J.G.; Slavov, S.; Subelj, A.; Young, E.D.

    2004-01-01

    The United Nations have studied how the oil and gas resource classification developed jointly by the SPE, the World Petroleum Congress (WPC) and the American Association of Petroleum Geologists (AAPG) could be harmonized with the United Nations Framework Classification (UNFC) for Solid Fuel and Mineral Resources (1). The United Nations has continued to build on this and other works, with support from many relevant international organizations, with the objective of updating the UNFC to apply to the extractive industries. The result is the United Nations Framework Classification for Energy and Mineral Resources (2) that this paper will present. Reserves and resources are categorized with respect to three sets of criteria: ??? Economic and commercial viability ??? Field project status and feasibility ??? The level of geologic knowledge The field project status criteria are readily recognized as the ones highlighted in the SPE/WPC/AAPG classification system of 2000. The geologic criteria absorb the rich traditions that form the primary basis for the Russian classification system, and the ones used to delimit, in part, proved reserves. Economic and commercial criteria facilitate the use of the classification in general, and reflect the commercial considerations used to delimit proved reserves in particular. The classification system will help to develop a common understanding of reserves and resources for all the extractive industries and will assist: ??? International and national resources management to secure supplies; ??? Industries' management of business processes to achieve efficiency in exploration and production; and ??? An appropriate basis for documenting the value of reserves and resources in financial statements.

  4. Population Genetic Structure of Glycyrrhiza inflata B. (Fabaceae) Is Shaped by Habitat Fragmentation, Water Resources and Biological Characteristics

    PubMed Central

    Yang, Lulu; Chen, Jianjun; Hu, Weiming; Yang, Tianshun; Zhang, Yanjun; Yukiyoshi, Tamura; Zhou, Yanyang; Wang, Ying

    2016-01-01

    Background Habitat fragmentation, water resources and biological characteristics are important factors that shape the genetic structure and geographical distribution of desert plants. Analysis of the relationships between these factors and population genetic variation should help to determine the evolutionary potential and conservation strategies for genetic resources for desert plant populations. As a traditional Chinese herb, Glycyrrhiza inflata B. (Fabaceae) is restricted to the fragmented desert habitat in China and has undergone a dramatic decline due to long-term over-excavation. Determining the genetic structure of the G. inflata population and identifying a core collection could help with the development of strategies to conserve this species. Results We investigated the genetic variation of 25 G. inflata populations based on microsatellite markers. A high level of population genetic divergence (FST = 0.257), population bottlenecks, reduced gene flow and moderate genetic variation (HE = 0.383) were detected. The genetic distances between the populations significantly correlated with the geographical distances, and this suggests that habitat fragmentation has driven a special genetic structure of G. inflata in China through isolation by distance. STRUCTURE analysis showed that G. inflata populations were structured into three clusters and that the populations belonged to multiple water systems, which suggests that water resources were related to the genetic structure of G. inflata. In addition, the biological characteristics of the perennial species G. inflata, such as its long-lived seeds, asexual reproduction, and oasis ecology, may be related to its resistance to habitat fragmentation. A core collection of G. inflata, that included 57 accessions was further identified, which captured the main allelic diversity of G. inflata. Conclusions Recent habitat fragmentation has accelerated genetic divergence. The population genetic structure of G. inflata has been

  5. 78 FR 51207 - Kobuk Valley National Park Subsistence Resource Commission (SRC) and the Denali National Park SRC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-20

    ... DEPARTMENT OF THE INTERIOR National Park Service [NPS-AKR-DENA-KOVA-DTS-13608; PPAKAKROR4; PPMPRLE1Y.LS0000] Kobuk Valley National Park Subsistence Resource Commission (SRC) and the Denali National Park SRC; Meetings AGENCY: National Park Service, Interior. ACTION: Meeting notice. SUMMARY: As...

  6. Water for the Nation: An overview of the USGS Water Resources Division

    USGS Publications Warehouse

    ,

    1998-01-01

    The Water Resources Division (WRD) of the U.S. Geological Survey (USGS) provides reliable, impartial, timely information needed to understand the Nation's water resources. WRD actively promotes the use of this information by decisionmakers to: * Minimize the loss of life and property as a result of water-related hazards such as floods, droughts, and land movement. * Effectively manage ground-water and surface-water resources for domestic, agricultural, commercial, industrial, recreational, and ecological uses. * Protect and enhance water resources for human health, aquatic health, and environmental quality. * Contribute to wise physical and economic development of the Nation's resources for the benefit of present and future generations.

  7. 76 FR 50494 - Water Resources Management Plan/Environmental Impact Statement, Mojave National Preserve, San...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-15

    ... Resources Management Plan/Environmental Impact Statement, Mojave National Preserve, San Bernardino County... Resources Management Plan/Environmental Impact Statement for Mojave National Preserve. SUMMARY: Pursuant to... preparing a Water Resources Management Plan/Environmental Impact Statement (WRMP/EIS). This plan is intended...

  8. Flexible Job-Shop Scheduling with Dual-Resource Constraints to Minimize Tardiness Using Genetic Algorithm

    NASA Astrophysics Data System (ADS)

    Paksi, A. B. N.; Ma'ruf, A.

    2016-02-01

    In general, both machines and human resources are needed for processing a job on production floor. However, most classical scheduling problems have ignored the possible constraint caused by availability of workers and have considered only machines as a limited resource. In addition, along with production technology development, routing flexibility appears as a consequence of high product variety and medium demand for each product. Routing flexibility is caused by capability of machines that offers more than one machining process. This paper presents a method to address scheduling problem constrained by both machines and workers, considering routing flexibility. Scheduling in a Dual-Resource Constrained shop is categorized as NP-hard problem that needs long computational time. Meta-heuristic approach, based on Genetic Algorithm, is used due to its practical implementation in industry. Developed Genetic Algorithm uses indirect chromosome representative and procedure to transform chromosome into Gantt chart. Genetic operators, namely selection, elitism, crossover, and mutation are developed to search the best fitness value until steady state condition is achieved. A case study in a manufacturing SME is used to minimize tardiness as objective function. The algorithm has shown 25.6% reduction of tardiness, equal to 43.5 hours.

  9. The National Resource Library for Youth with Disabilities*

    PubMed Central

    Ellis, Lynda B.M.; Blum, Robert W.; Geber, Gayle; Okinow, Nancy

    1987-01-01

    The University of Minnesota Program in Adolescent Health, in collaboration with the Society for Adolescent Medicine, has established a National Center for Youth with Disabilities. The National Center is developing an on-line National Resource Library for information related to this topic. The Library presently consists of three separate data files: journal articles, books, reports, and other bibliographic materials; model programs and projects; and a technical assistance network with referrals to experts in relevant fields. Two additional files, federal and state legislation and case law, and education and training materials, will be added in early 1988. The innovative design of this Library, including the user interface that permits it to be used by the general public, is described, and the maintenance of and modes of access to this resource are detailed. It is projected that over the first year of operation, use will grow to approximately 200 searches per month, from public and private institutions, groups and individuals, health care professionals, government officials, and parent and client groups.

  10. Development of resources and tools for mapping genetic sources of phenotypic variation

    USDA-ARS?s Scientific Manuscript database

    Commercial and experimental genetic resources were established and investigated for a range of reproductive and disease susceptibility phenotypes. The phenotyping efforts were accompanied with RNA and whole genome sequencing and novel assemblies of the swine genome. The efforts were complemented wit...

  11. 78 FR 54269 - Lake Clark National Park Subsistence Resource Commission; Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-03

    ... DEPARTMENT OF THE INTERIOR National Park Service [NPS-AKR-LACL-DTS-13687; PPAKAKROR4; PPMPRLE1Y.LS0000] Lake Clark National Park Subsistence Resource Commission; Meetings AGENCY: National Park Service...- 463, 86 Stat. 770), the National Park Service (NPS) is hereby giving notice that the Lake Clark...

  12. [Project design and implementation of the fourth national survey Chinese matiera medica resources].

    PubMed

    Huang, Lu-Qi; Lu, Jian-Wei; Guo, Lan-Ping; Zhang, Xiao-Bo; Zhao, Run-Huai; Zhang, Ben-Gang; Li, Yu; Su, Gang-Qiang; Li, Da-Ning

    2013-03-01

    The planning of the fourth national survey on Chinese materia medica resources shall follow the requirement of "carrying out the national survey on Chinese materia medica resources, strengthening the construction of Chinese materia medica resources monitoring and information network" which is according to the document issued by the State Council. Based on the responsibilities of State Administration of Traditional Chinese Medicine which is "organizing the survey, promoting the resource-protection, keeping development and rational utilization", combined with the key problems that need to be solved in current medicinal industry, the related instructions issued by central leadership and the recommendations from NPC delegates, CPPCC members and experts, the planning shall make overall plans and top-level design for the new round of national survey on Chinese materia medica resources.

  13. Forest resources of the Kootenai National Forest

    Treesearch

    Andrea M. Wilson; Patrick D. Miles

    2000-01-01

    THe Interior West Resource Inventory, Monitoring, and Evaluation (IWRIME) Program of the USDA Forest Service, Rocky Mountain Research Station (formerly known as the Intermountain Research Station), as part of its national Forest Inventory and Analysis (FIA) duties, entered into a cooperative agreement with the Northern Region (Region 1) for the inventory of its...

  14. Genetic ancestry of participants in the National Children's Study.

    PubMed

    Smith, Erin N; Jepsen, Kristen; Arias, Angelo D; Shepard, Peter J; Chambers, Christina D; Frazer, Kelly A

    2014-02-03

    The National Children's Study (NCS) is a prospective epidemiological study in the USA tasked with identifying a nationally representative sample of 100,000 children, and following them from their gestation until they are 21 years of age. The objective of the study is to measure environmental and genetic influences on growth, development, and health. Determination of the ancestry of these NCS participants is important for assessing the diversity of study participants and for examining the effect of ancestry on various health outcomes. We estimated the genetic ancestry of a convenience sample of 641 parents enrolled at the 7 original NCS Vanguard sites, by analyzing 30,000 markers on exome arrays, using the 1000 Genomes Project superpopulations as reference populations, and compared this with the measures of self-reported ethnicity and race. For 99% of the individuals, self-reported ethnicity and race agreed with the predicted superpopulation. NCS individuals self-reporting as Asian had genetic ancestry of either South Asian or East Asian groups, while those reporting as either Hispanic White or Hispanic Other had similar genetic ancestry. Of the 33 individuals who self-reported as Multiracial or Non-Hispanic Other, 33% matched the South Asian or East Asian groups, while these groups represented only 4.4% of the other reported categories. Our data suggest that self-reported ethnicity and race have some limitations in accurately capturing Hispanic and South Asian populations. Overall, however, our data indicate that despite the complexity of the US population, individuals know their ancestral origins, and that self-reported ethnicity and race is a reliable indicator of genetic ancestry.

  15. Idaho National Laboratory Cultural Resource Management Office FY 2010 Activity Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hollie K. Gilbert; Clayton F. Marler; Christina L. Olson

    2011-09-01

    The Idaho National Laboratory (INL) Site is home to vast numbers and a wide variety of important cultural resources representing at least a 13,500 year span of human land use in the region. As a federal agency, the Department of Energy, Idaho Operations Office (DOE-ID) has legal responsibility for the management and protection of the resources and has contracted these responsibilities to Battelle Energy Alliance (BEA). The BEA professional staff is committed to maintaining a cultural resource management program that accepts the challenge of preserving INL cultural resources in a manner reflecting their importance in local, regional, and national history.more » This report summarizes activities performed by the INL Cultural Resource Management Office (CRMO) staff during fiscal year 2010. This work is diverse, far-reaching and though generally confined to INL cultural resource compliance, also includes a myriad of professional and voluntary community activities. This document is intended to be informative to both internal and external stakeholders and to serve as a planning tool for future INL cultural resource management work.« less

  16. 77 FR 51753 - Daniel Boone National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-27

    ... DEPARTMENT OF AGRICULTURE Forest Service Daniel Boone National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Daniel Boone National Forest... relationships and to provide advice and recommendations to the Forest Service concerning projects and funding...

  17. [Resources and application of She's nationality wild medicinal plants].

    PubMed

    Lei, Hou-Xing; Li, Jian-Liang; Zheng, Song-Ming; Fan, Li-Hua; Li, Shui-Fu; Cheng, Wen-Liang; Hua, Jin-Wei; Yu, Hua-Li; Dai, De-Xiong; Xie, Yuan-Wei

    2014-08-01

    To make a thorough investigation of the common She's nationality wild medicinal plants resources in our country, including the species, the distribution, the folk application and the endemic medicinal plant species, Field surveyed was conducted with 25 She people mainly lived area (county, district or city) throughout the country, the folk prescription and treatment cases provided by She's medical personnel, the drug usage and dosage, the commonly used traditional She's medicine and drug samples were collected. And the distribution, growing environment of these plants were investigated, their characteristics, photographs, GPS data and track were record , and the fresh wax leaf or plants specimens were collected. In total 1 600 varieties of folk medicine of She's nationality, 450 disease names and 1 016 prescriptions were collected. 520 kinds of these medicinal plants were commonly used, growing mainly distributed in the southeastern China, about 200 meters above sea level to 1 500 meters. There are 5 First-Grade State protection wild plants (medicinal), 15 second-Grade State protection wild plants (medicinal), and 11 She characteristic medicinal plants in our study, they belong to 144 families, 312 genera 494 species, 2 subspecies, 17 varieties, 3 forms and 1 cultivated varieties of She's nationality. Folk medicine usage is different from the traditional Chinese medicine and ethnic medicine. This survey finds out the common She's nationality wild medicinal plants resources in China, including the species, the distribution, the folk application and commonly used drugs, and found the rare and endangered medicinal plants and the She's nationality endemic medicinal plants, which provides a basis for further development and use the traditional She's medicine resources.

  18. A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment.

    PubMed

    Hampel, Heather; Bennett, Robin L; Buchanan, Adam; Pearlman, Rachel; Wiesner, Georgia L

    2015-01-01

    The practice guidelines of the American College of Medical Genetics and Genomics (ACMG) and the National Society of Genetic Counselors (NSGC) are developed by members of the ACMG and NSGC to assist medical geneticists, genetic counselors, and other health-care providers in making decisions about appropriate management of genetic concerns, including access to and/or delivery of services. Each practice guideline focuses on a clinical or practice-based issue and is the result of a review and analysis of current professional literature believed to be reliable. As such, information and recommendations within the ACMG and NSGC joint practice guidelines reflect the current scientific and clinical knowledge at the time of publication, are current only as of their publication date, and are subject to change without notice as advances emerge. In addition, variations in practice, which take into account the needs of the individual patient and the resources and limitations unique to the institution or type of practice, may warrant approaches, treatments, and/or procedures that differ from the recommendations outlined in this guideline. Therefore, these recommendations should not be construed as dictating an exclusive course of management, nor does the use of such recommendations guarantee a particular outcome. Genetic counseling practice guidelines are never intended to displace a health-care provider's best medical judgment based on the clinical circumstances of a particular patient or patient population. Practice guidelines are published by the ACMG or the NSGC for educational and informational purposes only, and neither the ACMG nor the NSGC "approve" or "endorse" any specific methods, practices, or sources of information.Cancer genetic consultation is an important aspect of the care of individuals at increased risk of a hereditary cancer syndrome. Yet several patient, clinician, and system-level barriers hinder identification of individuals appropriate for cancer genetics

  19. Genetics Home Reference: glutaric acidemia type I

    MedlinePlus

    ... Acidemia I Orphanet: Glutaryl-CoA dehydrogenase deficiency Screening, Technology and Research in Genetics Virginia Department of Health (PDF) Patient Support and Advocacy Resources (3 links) Children Living with Inherited Metabolic Diseases (CLIMB) National Organization ...

  20. 75 FR 26918 - North Gifford Pinchot National Forest Resource Advisory Committee Meeting Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-13

    ... DEPARTMENT OF AGRICULTURE Forest Service North Gifford Pinchot National Forest Resource Advisory Committee Meeting Notice AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The North Gifford Pinchot National Forest Resource Advisory Committee will meet on Wednesday, June 9, 2010 at the Salkum...

  1. Resources for Teaching about Nationalism, 1812 to the Civil War.

    ERIC Educational Resources Information Center

    Seiter, David

    1987-01-01

    Highlights five resources for teaching about the rise of U.S. nationalism between 1812 and 1865 available from the Educational Resource Information Center (ERIC). Items included are: (1) the War of 1812; (2) the annexation of Texas; (3) the Kansas-Nebraska Act; and (4) the question of slavery. (BSR)

  2. 75 FR 80063 - National Center for Research Resources; Notice of Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-21

    ... of Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... U.S.C. App.), notice is hereby given of meetings of the National Advisory Research Resources Council...

  3. Using the GRIN-Global System to Identify Useful Plant Genetic Resources & Information

    USDA-ARS?s Scientific Manuscript database

    The GRIN-Global (GG) System has been developed to provide the world's crop genebanks and plant genetic resource (PGR) users with a powerful, flexible, easy-to-use PGR information management system. Developed jointly by the USDA Agricultural Research Service, Bioversity International and the Global C...

  4. [Study on spatial distribution characteristics of traditional Chinese medicine resource species richness based on national census of Chinese medicine resources (pilot)].

    PubMed

    Zhang, Xiao-Bo; Wang, Hui; Jing, Zhi-Xian; Li, Meng; Guo, Lan-Ping; Huang, Lu-Qi

    2017-11-01

    Based on the data collected by the census team in the national census information management system, the spatial autocorrelation analysis method was used to analyze the similarity of the richness of Chinese herbal medicine resources in the investigated counties. The results showed that the species richness in the investigated counties appeared a tendency to focus on the distribution of the characteristics. Among them, the areas with sparse resources are concentrated in most areas of the north of the Yangtze River, northwest and most areas of Tibet. The areas with abundant resources are concentrated in the areas south of the Yangtze River. The results showed that there were significant differences in the abundance of traditional Chinese medicine resources between regions. The results showed that there were significant differences in the abundance of traditional Chinese medicine resources between regions. Due to the large differences in the land area between the county and the richness of the types of traditional Chinese medicine resources, it is proposed to increase the land area of the traditional Chinese medicine resource census when allocating the fourth national census of Chinese medicine resources by the "factor method", and the richness of traditional Chinese medicine and other indicators, in order to give full play to the efficiency of transfer payment system. Based on the county area and the rich variety of traditional Chinese medicine resources, combined with the national drug resources census pilot work carried out, it is recommended to focus on attention and support in the national medicine resources census work, personnel team, funding, summary of results on the western and southern provinces. Copyright© by the Chinese Pharmaceutical Association.

  5. National Aquatic Resource Surveys & Statistics: Role of statistics in the development of a national monitoring program

    EPA Science Inventory

    The National Aquatic Resource Surveys (NARS) are a series of four statistical surveys conducted by the U.S. Environmental Protection Agency working in collaboration with states, tribal nations and other federal agencies. The surveys are conducted for lakes and reservoirs, streams...

  6. National Electric Sector Cybersecurity Organization Resource (NESCOR)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    The goal of the National Electric Sector Cybersecurity Organization Resource (NESCOR) project was to address cyber security issues for the electric sector, particularly in the near and mid-term. The following table identifies the strategies from the DOE Roadmap to Achieve Energy Delivery Systems Cybersecurity published in September 2011 that are applicable to the NESCOR project.

  7. The National Plant Germplasm System and GRIN-Global

    USDA-ARS?s Scientific Manuscript database

    The National Plant Germplasm System (NPGS) is a cooperative effort by public and private organizations to preserve plant genetic diversity. Federal and State personnel at 20 sites are responsible for approximately 547,000 unique accessions of a wide array of plant genetic resources (PGR) representi...

  8. 77 FR 46375 - Chippewa National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ... Schools and Community Self-Determination Act (Pub. L. 110-343) (the Act) and operates in compliance with... review with the Chippewa National Forest Resource Advisory Committee members their roles and...

  9. Idaho National Laboratory Cultural Resource Management Office FY 2011 Activity Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Julie Braun Williams; Brenda R. Pace; Hollie K. Gilbert

    The Idaho National Laboratory (INL) Site is home to vast numbers and a wide variety of important cultural resources representing at least a 13,500 year span of human land use in the region. As a federal agency, the Department of Energy, Idaho Operations Office (DOE-ID) has legal responsibility for the management and protection of the resources and has contracted these responsibilities to Battelle Energy Alliance (BEA). The BEA professional staff is committed to maintaining a cultural resource management program that accepts the challenge of preserving INL cultural resources in a manner reflecting their importance in local, regional, and national history.more » This report is intended as a stand-alone document that summarizes activities performed by the INL Cultural Resource Management Office (CRMO) staff during fiscal year 2011. This work is diverse, far-reaching and though generally confined to INL cultural resource compliance, also includes a myriad of professional and voluntary community activities. This document is intended to be informative to both internal and external stakeholders, serve as a planning tool for future INL cultural resource management work, and meet an agreed upon legal requirement.« less

  10. Career Planning: Developing the Nation's Primary Resource.

    ERIC Educational Resources Information Center

    Jarvis, Phillip S.

    Career planning is the most critical ingredient in developing a nation's primary resource, its workers. A 1988 Gallup Poll showed that 62 percent of U.S. workers had no career goal when they began their first job, and more than 50 percent felt they were in the wrong job. The same results probably could be applied to Canada. Career planning skills…

  11. Forest resources of nations in relation to human well-being.

    PubMed

    Kauppi, Pekka E; Sandström, Vilma; Lipponen, Antti

    2018-01-01

    A universal turnaround has been detected in many countries of the World from shrinking to expanding forests. The forest area of western Europe expanded already in the 19th century. Such early trends of forest resources cannot be associated with the rapid rise of atmospheric carbon dioxide nor with the anthropogenic climate change, which have taken place since the mid 20th century. Modern, most recent spatial patterns of forest expansions and contractions do not correlate with the geography of climate trends nor with dry versus moist areas. Instead, the forest resources trends of nations correlate positively with UNDP Human Development Index. This indicates that forest resources of nations have improved along with progress in human well-being. Highly developed countries apply modern agricultural methods on good farmlands and abandon marginal lands, which become available for forest expansion. Developed countries invest in sustainable programs of forest management and nature protection. Our findings are significant for predicting the future of the terrestrial carbon sink. They suggest that the large sink of carbon recently observed in forests of the World will persist, if the well-being of people continues to improve. However, despite the positive trends in domestic forests, developed nations increasingly outsource their biomass needs abroad through international trade, and all nations rely on unsustainable energy use and wasteful patterns of material consumption.

  12. National Patterns of Science and Technology Resources, 1982.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC.

    The National Science Foundation, in attempting to monitor the health of U.S. science and technology, assembles and analyzes comprehensive measures of the financial and human resources that various sectors (government, industry, academia, and other nonprofit institutions) devote to scientific and technological activities. This annual report…

  13. Photos of Sampling for the National Aquatic Resource Surveys

    EPA Pesticide Factsheets

    The National Aquatic Resource Surveys study all types of waters: rivers and streams, lakes and reservoirs, Great Lakes, coastal waters and wetlands. These photos were taken during in-the-field sampling for recent reports.

  14. MSFC Optical Metrology: A National Resource

    NASA Technical Reports Server (NTRS)

    Burdine, Robert

    1998-01-01

    A national need exists for Large Diameter Optical Metrology Services. These services include the manufacture, testing, and assurance of precision and control necessary to assure the success of large optical projects. "Best Practices" are often relied on for manufacture and quality controls while optical projects are increasingly more demanding and complex. Marshall Space Flight Center (MSFC) has acquired unique optical measurement, testing and metrology capabilities through active participation in a wide variety of NASA optical programs. An overview of existing optical facilities and metrology capabilities is given with emphasis on use by other optical projects. Cost avoidance and project success is stressed through use of existing MSFC facilities and capabilities for measurement and metrology controls. Current issues in large diameter optical metrology are briefly reviewed. The need for a consistent and long duration Large Diameter Optical Metrology Service Group is presented with emphasis on the establishment of a National Large Diameter Optical Standards Laboratory. Proposals are made to develop MSFC optical standards and metrology capabilities as the primary national standards resource, providing access to MSFC Optical Core Competencies for manufacturers and researchers. Plans are presented for the development of a national lending library of precision optical standards with emphasis on cost avoidance while improving measurement assurance.

  15. National Hydroelectric Power Resources Study:Regional Assessment: Volume XXIII: Alaska and Hawaii

    DTIC Science & Technology

    1981-09-01

    amount of recoverable geothermal energy is still unknown, a test well (HGP-A) was drilled 6,450 feet into the eastern rift of Kilauea volcano on...US Army Corps of Engineers National Hydroelectric Power Resources Study Volume XXIII September 1 981 Regional Assessment: Alaska and Hawaii ...National Hydroelectric Power Resources Study: Final Regional Assessment; Alaska and Hawaii IS. PERFORMING ORG. REPORT NUMBER IWR 82-𔃻-23 7. AUTHOR(a) 8

  16. 76 FR 54196 - Public Meeting, Cherokee National Forest Secure Rural Schools Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-31

    ... DEPARTMENT OF AGRICULTURE Forest Service Public Meeting, Cherokee National Forest Secure Rural.... Department of Agriculture, Forest Service, Cherokee National Forest Secure Rural Schools Resource Advisory... Schools Resource Advisory Committee (RAC) proposes projects and funding to the Secretary of Agriculture...

  17. 75 FR 49498 - National Center for Research Resources; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-13

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... U.S.C. App.), notice is hereby given of a meeting of the National Advisory Research Resources... 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could...

  18. 75 FR 18216 - National Center for Research Resources; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... U.S.C. App.), notice is hereby given of a meeting of the National Advisory Research Resources... 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and/or contract proposals...

  19. 76 FR 62814 - National Center For Research Resources; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-11

    ..., Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical Technology; 93.389, Research... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center For Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  20. 75 FR 32187 - National Center for Research Resources: Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-07

    ..., Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical Technology; 93.389, Research... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  1. 76 FR 41195 - National Forests In Mississippi, Tombigbee and Holly Springs Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... DEPARTMENT OF AGRICULTURE Forest Service National Forests In Mississippi, Tombigbee and Holly Springs Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Tombigbee and Holly Springs National Forests Resource Advisory Committee will meet in Starkville, MS. The...

  2. 76 FR 41196 - National Forests in Mississippi, Tombigbee and Holly Springs Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... DEPARTMENT OF AGRICULTURE Forest Service National Forests in Mississippi, Tombigbee and Holly Springs Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Tombigbee and Holly Springs National Forests Resource Advisory Committee will meet in Starkville, MS. The...

  3. Forest resources of the Beaverhead-Deerlodge National Forest

    Treesearch

    Larry T. DeBlander

    2001-01-01

    The Interior West Resource Inventory, Monitoring, and Evaluation (IWRIME) Program of the USDA Forest Service, Rocky Mountain Research Station (formerly the Intermountain Research Station), as part of its national Forest Inventory and Analysis (FIA) duties, entered into a cooperative agreement with the Northern Region (Region 1) for the inventory of its...

  4. 76 FR 29254 - National Center for Research Resources; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-20

    ... Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research; 93.371... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  5. 75 FR 32187 - National Center for Research Resources; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-07

    ... Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical Technology; 93... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  6. 75 FR 52538 - National Center for Research Resources; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-26

    .... 93.306, Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical Technology; 93.389... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  7. 76 FR 369 - National Center for Research Resources; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-04

    .... 93.306, Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical Technology; 93.389... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  8. 76 FR 6627 - National Center for Research Resources; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    .... 93.306, Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical Technology; 93.389... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  9. 76 FR 12123 - National Center for Research Resources; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-04

    ... Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research; 93.371... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  10. 75 FR 54895 - National Center for Research Resources; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    ... Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  11. 76 FR 4121 - National Center for Research Resources; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-24

    ... Nos. 93.306, Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical Technology; 93.389... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  12. 76 FR 59709 - National Center for Research Resources; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ... Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical Technology; 93... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  13. 76 FR 16797 - National Center for Research Resources; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-25

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special... funding cycle. (Catalogue of Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333...

  14. 75 FR 28262 - National Center for Research Resources; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-20

    ....306, Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical Technology; 93.389, Research... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  15. 76 FR 57748 - National Center for Research Resources; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ... Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical Technology; 93... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  16. 76 FR 40384 - National Center for Research Resources; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    .... 93.306, Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical Technology; 93.389... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  17. 75 FR 61768 - National Center for Research Resources; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-06

    ....306, Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical Technology; 93.389, Research... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research... unwarranted invasion of personal privacy. Name of Committee: National Center for Research Resources Special...

  18. Calculation of coal resources using ARC/INFO and Earth Vision; methodology for the National Coal Resource Assessment

    USGS Publications Warehouse

    Roberts, L.N.; Biewick, L.R.

    1999-01-01

    This report documents a comparison of two methods of resource calculation that are being used in the National Coal Resource Assessment project of the U.S. Geological Survey (USGS). Tewalt (1998) discusses the history of using computer software packages such as GARNET (Graphic Analysis of Resources using Numerical Evaluation Techniques), GRASS (Geographic Resource Analysis Support System), and the vector-based geographic information system (GIS) ARC/INFO (ESRI, 1998) to calculate coal resources within the USGS. The study discussed here, compares resource calculations using ARC/INFO* (ESRI, 1998) and EarthVision (EV)* (Dynamic Graphics, Inc. 1997) for the coal-bearing John Henry Member of the Straight Cliffs Formation of Late Cretaceous age in the Kaiparowits Plateau of southern Utah. Coal resource estimates in the Kaiparowits Plateau using ARC/INFO are reported in Hettinger, and others, 1996.

  19. Scaling Up Scientific Discovery in Sleep Medicine: The National Sleep Research Resource.

    PubMed

    Dean, Dennis A; Goldberger, Ary L; Mueller, Remo; Kim, Matthew; Rueschman, Michael; Mobley, Daniel; Sahoo, Satya S; Jayapandian, Catherine P; Cui, Licong; Morrical, Michael G; Surovec, Susan; Zhang, Guo-Qiang; Redline, Susan

    2016-05-01

    Professional sleep societies have identified a need for strategic research in multiple areas that may benefit from access to and aggregation of large, multidimensional datasets. Technological advances provide opportunities to extract and analyze physiological signals and other biomedical information from datasets of unprecedented size, heterogeneity, and complexity. The National Institutes of Health has implemented a Big Data to Knowledge (BD2K) initiative that aims to develop and disseminate state of the art big data access tools and analytical methods. The National Sleep Research Resource (NSRR) is a new National Heart, Lung, and Blood Institute resource designed to provide big data resources to the sleep research community. The NSRR is a web-based data portal that aggregates, harmonizes, and organizes sleep and clinical data from thousands of individuals studied as part of cohort studies or clinical trials and provides the user a suite of tools to facilitate data exploration and data visualization. Each deidentified study record minimally includes the summary results of an overnight sleep study; annotation files with scored events; the raw physiological signals from the sleep record; and available clinical and physiological data. NSRR is designed to be interoperable with other public data resources such as the Biologic Specimen and Data Repository Information Coordinating Center Demographics (BioLINCC) data and analyzed with methods provided by the Research Resource for Complex Physiological Signals (PhysioNet). This article reviews the key objectives, challenges and operational solutions to addressing big data opportunities for sleep research in the context of the national sleep research agenda. It provides information to facilitate further interactions of the user community with NSRR, a community resource. © 2016 Associated Professional Sleep Societies, LLC.

  20. National Aquatic Resource Surveys (NARS) Technical Support and Research

    EPA Science Inventory

    OW has overall responsibility for all operational aspects of the National Aquatic Resource Surveys (NARS) and funds all field operations, laboratory analyses, and information management. They are responsible for preparation of all documents, including QAPP, field operation manual...

  1. Idaho National Laboratory Cultural Resource Monitoring Report for Fiscal Year 2016

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gilbert, Hollie Kae; Holmer, Marie Pilkington; Olson, Christina Liegh

    This report describes the cultural resource monitoring activities of the Idaho National Laboratory’s (INL) Cultural Resource Management (CRM) Office during fiscal year (FY) 2016. Overall monitoring included surveillance of the following 23 individual cultural resource localities: two locations with human remains, one of which is also a cave; seven additional caves; six prehistoric archaeological sites; four historic archaeological sites; one historic trail; Experimental Breeder Reactor I (EBR-I), a National Historic Landmark; Aircraft Nuclear Propulsion (ANP) objects located at EBR-I; and one Arco Naval Proving Ground (NPG) property, CF-633 and related objects and structures. Several INL work processes and projects weremore » also monitored to confirm compliance with original INL CRM recommendations and assess the effects of ongoing work. On one occasion, ground disturbing activities within the boundaries of the Critical Infrastructure Test Range Complex (CITRC) were observed by INL CRM staff prepared to respond to any additional finds of Native American human remains. Additionally, the CRM office was notified during two Trespass Investigations conducted by INL Security. Most of the cultural resources monitored in FY 2016 exhibited no adverse impacts, resulting in Type 1 impact assessments. However, Type 2 impacts were noted five times. Three previously reported Type 2 impacts were once again documented at the EBR-I National Historic Landmark, including spalling and deterioration of bricks due to inadequate drainage, minimal maintenance, and rodent infestation. The ANP engines and locomotive on display at the EBR-I Visitors Center also exhibited impacts related to long term exposure. Finally, most of the Arco NPG properties monitored at Central Facilities Area exhibited problems with lack of timely and appropriate maintenance as well as inadequate drainage. No new Type 3 or Type 4 impacts that adversely affected significant cultural resources and threatened

  2. Implementation of Strategies to Leverage Public and Private Resources for National Security Workforce Development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2009-04-01

    This report documents implementation strategies to leverage public and private resources for the development of an adequate national security workforce as part of the National Security Preparedness Project (NSPP), being performed under a U.S. Department of Energy (DOE)/National Nuclear Security Administration (NNSA) grant. There are numerous efforts across the United States to develop a properly skilled and trained national security workforce. Some of these efforts are the result of the leveraging of public and private dollars. As budget dollars decrease and the demand for a properly skilled and trained national security workforce increases, it will become even more important tomore » leverage every education and training dollar. This report details some of the efforts that have been implemented to leverage public and private resources, as well as implementation strategies to further leverage public and private resources.« less

  3. National Conference on Integrated Resource Planning: Proceedings

    NASA Astrophysics Data System (ADS)

    Until recently, state regulators have focused most of their attention on the development of least-cost or integrated resource planning (IRP) processes for electric utilities. A number of commissions are beginning to scrutinize the planning processes of local gas distribution companies (LDCs) because of the increased control that LDCs have over their purchased gas costs (as well as the associated risks) and because of questions surrounding the role and potential of gas end-use efficiency options. Traditionally, resource planning (LDCs) has concentrated on options for purchasing and storing gas. Integrated resource planning involves the creation of a process in which supply-side and demand-side options are integrated to create a resource mix that reliably satisfies customers' short-term and long-term energy service needs at the lowest cost. As applied to gas utilities, an integrated resource plan seeks to balance cost and reliability, and should not be interpreted simply as the search for lowest commodity costs. The National Association of Regulatory Utility Commissioners' (NARUC) Energy Conservation committee asked Lawrence Berkeley Laboratory (LBL) to survey state PUCs to determine the extent to which they have undertaken least cost planning for gas utilities. The survey included the following topics: status of state PUC least-cost planning regulations and practices for gas utilities; type and scope of natural gas DSM programs in effect, including fuel substitution; economic tests and analysis methods used to evaluate DSM programs; relationship between prudency reviews of gas utility purchasing practices and integrated resource planning; and key regulatory issues facing gas utilities during the next five years.

  4. 75 FR 51238 - Manti-La Sal National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-19

    ... DEPARTMENT OF AGRICULTURE Forest Service Manti-La Sal National Forest Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Manti-La Sal National Forest..., 319 North Carbon Avenue, Price, Utah. Written comments should be sent to Rosann Fillmore, Manti- La...

  5. Complex Genetic Effects on Early Vegetative Development Shape Resource Allocation Differences Between Arabidopsis lyrata Populations

    PubMed Central

    Remington, David L.; Leinonen, Päivi H.; Leppälä, Johanna; Savolainen, Outi

    2013-01-01

    Costs of reproduction due to resource allocation trade-offs have long been recognized as key forces in life history evolution, but little is known about their functional or genetic basis. Arabidopsis lyrata, a perennial relative of the annual model plant A. thaliana with a wide climatic distribution, has populations that are strongly diverged in resource allocation. In this study, we evaluated the genetic and functional basis for variation in resource allocation in a reciprocal transplant experiment, using four A. lyrata populations and F2 progeny from a cross between North Carolina (NC) and Norway parents, which had the most divergent resource allocation patterns. Local alleles at quantitative trait loci (QTL) at a North Carolina field site increased reproductive output while reducing vegetative growth. These QTL had little overlap with flowering date QTL. Structural equation models incorporating QTL genotypes and traits indicated that resource allocation differences result primarily from QTL effects on early vegetative growth patterns, with cascading effects on later vegetative and reproductive development. At a Norway field site, North Carolina alleles at some of the same QTL regions reduced survival and reproductive output components, but these effects were not associated with resource allocation trade-offs in the Norway environment. Our results indicate that resource allocation in perennial plants may involve important adaptive mechanisms largely independent of flowering time. Moreover, the contributions of resource allocation QTL to local adaptation appear to result from their effects on developmental timing and its interaction with environmental constraints, and not from simple models of reproductive costs. PMID:23979581

  6. Hazardous Waste Resources for Tribal Nations in the Midwest

    EPA Pesticide Factsheets

    Hazardous waste on tribal lands presents a unique set of opportunities and obstacles. This website is intended to be a host for resources that can help Tribal Nations understand the dynamics of hazardous waste and provide guidance on building tribal hazard

  7. National Human Resource Development: A Multi-Level Perspective

    ERIC Educational Resources Information Center

    Nair, Prakash Krishnan; Ke, Jie; Al-Emadi, Mohammed A. S.; Coningham, Beatriz; Conser, Jessica; Cornachione, Edgar; Devassy, Seeja Mary; Dhirani, Khalil

    2007-01-01

    Although there are have been some studies on National Human Resource Development and HRD practices in certain countries, literature shows that we have just scratched the surface in terms of the number of countries we know about. This exploratory study reviews research associated with HRD policies and practices in Brazil, China, India, Italy,…

  8. Valuation of crop genetic resources in Kaski, Nepal: farmers' willingness to pay for rice landraces conservation.

    PubMed

    Poudel, Diwakar; Johnsen, Fred H

    2009-01-01

    Crop genetic resources constitute an important aspect of biodiversity conservation, both because of their direct value to the farmers and due to their indirect global value. This study uses the contingent valuation method to document the economic value of crop genetic resources based on the farmers' willingness to pay for conservation. A total of 107 households in Kaski, Nepal were surveyed in November 2003. Their mean willingness to pay was USD 4.18 for in situ and USD 2.20 for ex situ conservation per annum. Landholding size, household size, education level, socio-economic status, sex of respondent, number of crop landraces grown, and knowledge on biodiversity influenced the willingness to pay for in situ conservation, whereas only landholding size and household size influenced the willingness to pay for ex situ conservation. The respondents were willing to contribute more for in situ than ex situ conservation because of the additional effect of direct use and direct involvement of the farmers in in situ conservation. This study supports the view that economic valuation of crop genetic resources can assist the policy makers in setting conservation priorities.

  9. Mapping genetic diversity of cherimoya (Annona cherimola Mill.): application of spatial analysis for conservation and use of plant genetic resources.

    PubMed

    Zonneveld, Maarten van; Scheldeman, Xavier; Escribano, Pilar; Viruel, María A; Van Damme, Patrick; Garcia, Willman; Tapia, César; Romero, José; Sigueñas, Manuel; Hormaza, José I

    2012-01-01

    There is a growing call for inventories that evaluate geographic patterns in diversity of plant genetic resources maintained on farm and in species' natural populations in order to enhance their use and conservation. Such evaluations are relevant for useful tropical and subtropical tree species, as many of these species are still undomesticated, or in incipient stages of domestication and local populations can offer yet-unknown traits of high value to further domestication. For many outcrossing species, such as most trees, inbreeding depression can be an issue, and genetic diversity is important to sustain local production. Diversity is also crucial for species to adapt to environmental changes. This paper explores the possibilities of incorporating molecular marker data into Geographic Information Systems (GIS) to allow visualization and better understanding of spatial patterns of genetic diversity as a key input to optimize conservation and use of plant genetic resources, based on a case study of cherimoya (Annona cherimola Mill.), a Neotropical fruit tree species. We present spatial analyses to (1) improve the understanding of spatial distribution of genetic diversity of cherimoya natural stands and cultivated trees in Ecuador, Bolivia and Peru based on microsatellite molecular markers (SSRs); and (2) formulate optimal conservation strategies by revealing priority areas for in situ conservation, and identifying existing diversity gaps in ex situ collections. We found high levels of allelic richness, locally common alleles and expected heterozygosity in cherimoya's putative centre of origin, southern Ecuador and northern Peru, whereas levels of diversity in southern Peru and especially in Bolivia were significantly lower. The application of GIS on a large microsatellite dataset allows a more detailed prioritization of areas for in situ conservation and targeted collection across the Andean distribution range of cherimoya than previous studies could do, i.e. at

  10. Mapping Genetic Diversity of Cherimoya (Annona cherimola Mill.): Application of Spatial Analysis for Conservation and Use of Plant Genetic Resources

    PubMed Central

    van Zonneveld, Maarten; Scheldeman, Xavier; Escribano, Pilar; Viruel, María A.; Van Damme, Patrick; Garcia, Willman; Tapia, César; Romero, José; Sigueñas, Manuel; Hormaza, José I.

    2012-01-01

    There is a growing call for inventories that evaluate geographic patterns in diversity of plant genetic resources maintained on farm and in species' natural populations in order to enhance their use and conservation. Such evaluations are relevant for useful tropical and subtropical tree species, as many of these species are still undomesticated, or in incipient stages of domestication and local populations can offer yet-unknown traits of high value to further domestication. For many outcrossing species, such as most trees, inbreeding depression can be an issue, and genetic diversity is important to sustain local production. Diversity is also crucial for species to adapt to environmental changes. This paper explores the possibilities of incorporating molecular marker data into Geographic Information Systems (GIS) to allow visualization and better understanding of spatial patterns of genetic diversity as a key input to optimize conservation and use of plant genetic resources, based on a case study of cherimoya (Annona cherimola Mill.), a Neotropical fruit tree species. We present spatial analyses to (1) improve the understanding of spatial distribution of genetic diversity of cherimoya natural stands and cultivated trees in Ecuador, Bolivia and Peru based on microsatellite molecular markers (SSRs); and (2) formulate optimal conservation strategies by revealing priority areas for in situ conservation, and identifying existing diversity gaps in ex situ collections. We found high levels of allelic richness, locally common alleles and expected heterozygosity in cherimoya's putative centre of origin, southern Ecuador and northern Peru, whereas levels of diversity in southern Peru and especially in Bolivia were significantly lower. The application of GIS on a large microsatellite dataset allows a more detailed prioritization of areas for in situ conservation and targeted collection across the Andean distribution range of cherimoya than previous studies could do, i.e. at

  11. Creating the spatial framework for National Aquatic Resource Surveys (NARS): Melding National Aquatic Data Sets with Survey Requirements

    EPA Science Inventory

    The U.S. EPA’s National Aquatic Resource Surveys (NARS) require a consistent spatial representation of the resource target populations being monitored (i.e., rivers and streams, lakes, coastal waters, and wetlands). A sample frame is the GIS representation of this target popula...

  12. Genetic ancestry of participants in the National Children’s Study

    PubMed Central

    2014-01-01

    Background The National Children’s Study (NCS) is a prospective epidemiological study in the USA tasked with identifying a nationally representative sample of 100,000 children, and following them from their gestation until they are 21 years of age. The objective of the study is to measure environmental and genetic influences on growth, development, and health. Determination of the ancestry of these NCS participants is important for assessing the diversity of study participants and for examining the effect of ancestry on various health outcomes. Results We estimated the genetic ancestry of a convenience sample of 641 parents enrolled at the 7 original NCS Vanguard sites, by analyzing 30,000 markers on exome arrays, using the 1000 Genomes Project superpopulations as reference populations, and compared this with the measures of self-reported ethnicity and race. For 99% of the individuals, self-reported ethnicity and race agreed with the predicted superpopulation. NCS individuals self-reporting as Asian had genetic ancestry of either South Asian or East Asian groups, while those reporting as either Hispanic White or Hispanic Other had similar genetic ancestry. Of the 33 individuals who self-reported as Multiracial or Non-Hispanic Other, 33% matched the South Asian or East Asian groups, while these groups represented only 4.4% of the other reported categories. Conclusions Our data suggest that self-reported ethnicity and race have some limitations in accurately capturing Hispanic and South Asian populations. Overall, however, our data indicate that despite the complexity of the US population, individuals know their ancestral origins, and that self-reported ethnicity and race is a reliable indicator of genetic ancestry. PMID:24490717

  13. Estimation of loss of genetic diversity in modern Japanese cultivars by comparison of diverse genetic resources in Asian pear (Pyrus spp.).

    PubMed

    Nishio, Sogo; Takada, Norio; Saito, Toshihiro; Yamamoto, Toshiya; Iketani, Hiroyuki

    2016-06-14

    Pears (Pyrus spp.) are one of the most important fruit crops in temperate regions. Japanese pear breeding has been carried out for over 100 years, working to release new cultivars that have good fruit quality and other desirable traits. Local cultivar 'Nijisseiki' and its relatives, which have excellent fruit texture, have been repeatedly used as parents in the breeding program. This strategy has led to inbreeding within recent cultivars and selections. To avoid inbreeding depression, we need to clarify the degree of inbreeding among crossbred cultivars and to introgress genetic resources that are genetically different from modern cultivars and selections. The objective of the present study was to clarify the genetic relatedness between modern Japanese pear cultivars and diverse Asian pear genetic resources. We genotyped 207 diverse accessions by using 19 simple sequence repeat (SSR) markers. The heterozygosity and allelic richness of modern cultivars was obviously decreased compared with that of wild individuals, Chinese pear cultivars, and local cultivars. In analyses using Structure software, the 207 accessions were classified into four clusters (K = 4): one consisting primarily of wild individuals, one of Chinese pear cultivars, one of local cultivars from outside the Kanto region, and one containing both local cultivars from the Kanto region and crossbred cultivars. The results of principal coordinate analysis (PCoA) were similar to those from the Structure analysis. Wild individuals and Chinese pears appeared to be distinct from other groups, and crossbred cultivars became closer to 'Nijisseiki' as the year of release became more recent. Both Structure and PCoA results suggest that the modern Japanese pear cultivars are genetically close to local cultivars that originated in the Kanto region, and that the genotypes of the modern cultivars were markedly biased toward 'Nijisseiki'. Introgression of germplasm from Chinese pear and wild individuals that are

  14. Forest resources of the Shawnee National Forest, 2007

    Treesearch

    C.M. Kurtz; S.J. Crocker

    2010-01-01

    This publication provides an overview of forest resource attributes for the Shawnee National Forest based on an annual inventory conducted by the Forest Inventory and Analysis (FIA) program of the U.S. Forest Service, Northern Research Station. These estimates, along with web-posted core tables, will be updated annually. For more information, please refer to page 4 of...

  15. Forest Resources of Isle Royale National Park 2010

    Treesearch

    Wilfred J. Previant; Linda M. Nagel; Scott A. Pugh; Christopher W. Woodall

    2012-01-01

    This publication provides a baseline overview of forest resources for Isle Royale National Park (Isle Royale) using data from the Forest Inventory and Analysis (FIA) Program of the U.S. Department of Agriculture, Forest Service. The availability of permanent FIA plots allows for the first-ever comparison of Isle Royale's forest conditions (2006-2010) to reserved...

  16. Information resources at the National Center for Biotechnology Information.

    PubMed Central

    Woodsmall, R M; Benson, D A

    1993-01-01

    The National Center for Biotechnology Information (NCBI), part of the National Library of Medicine, was established in 1988 to perform basic research in the field of computational molecular biology as well as build and distribute molecular biology databases. The basic research has led to new algorithms and analysis tools for interpreting genomic data and has been instrumental in the discovery of human disease genes for neurofibromatosis and Kallmann syndrome. The principal database responsibility is the National Institutes of Health (NIH) genetic sequence database, GenBank. NCBI, in collaboration with international partners, builds, distributes, and provides online and CD-ROM access to over 112,000 DNA sequences. Another major program is the integration of multiple sequences databases and related bibliographic information and the development of network-based retrieval systems for Internet access. PMID:8374583

  17. Preparing for a National Emergency: The Committee on Conservation of Cultural Resources, 1939-1944

    ERIC Educational Resources Information Center

    Aikin, Jane

    2007-01-01

    In March 1940 the U.S. National Resources Planning Board established the Committee on Conservation of Cultural Resources to plan for the protection of federal cultural institutions during national emergencies. The committee provided a mechanism to bring officials together to consider protective measures for and evacuation of valuable books,…

  18. 77 FR 54877 - Deschutes and Ochoco National Forests Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... National Forests Resource Advisory Committee will meet in Bend, Oregon. The purpose of the meeting is to... Hawthorne Avenue, Bend, OR 97701. Send written comments to John Allen as Designated Federal Official, for..., Deschutes National Forest, 63095 Deschutes Market Road., Bend, OR 97701 or electronically to [email protected

  19. Mouse Genome Informatics (MGI) Resource: Genetic, Genomic, and Biological Knowledgebase for the Laboratory Mouse.

    PubMed

    Eppig, Janan T

    2017-07-01

    The Mouse Genome Informatics (MGI) Resource supports basic, translational, and computational research by providing high-quality, integrated data on the genetics, genomics, and biology of the laboratory mouse. MGI serves a strategic role for the scientific community in facilitating biomedical, experimental, and computational studies investigating the genetics and processes of diseases and enabling the development and testing of new disease models and therapeutic interventions. This review describes the nexus of the body of growing genetic and biological data and the advances in computer technology in the late 1980s, including the World Wide Web, that together launched the beginnings of MGI. MGI develops and maintains a gold-standard resource that reflects the current state of knowledge, provides semantic and contextual data integration that fosters hypothesis testing, continually develops new and improved tools for searching and analysis, and partners with the scientific community to assure research data needs are met. Here we describe one slice of MGI relating to the development of community-wide large-scale mutagenesis and phenotyping projects and introduce ways to access and use these MGI data. References and links to additional MGI aspects are provided. © The Author 2017. Published by Oxford University Press.

  20. Mouse Genome Informatics (MGI) Resource: Genetic, Genomic, and Biological Knowledgebase for the Laboratory Mouse

    PubMed Central

    Eppig, Janan T.

    2017-01-01

    Abstract The Mouse Genome Informatics (MGI) Resource supports basic, translational, and computational research by providing high-quality, integrated data on the genetics, genomics, and biology of the laboratory mouse. MGI serves a strategic role for the scientific community in facilitating biomedical, experimental, and computational studies investigating the genetics and processes of diseases and enabling the development and testing of new disease models and therapeutic interventions. This review describes the nexus of the body of growing genetic and biological data and the advances in computer technology in the late 1980s, including the World Wide Web, that together launched the beginnings of MGI. MGI develops and maintains a gold-standard resource that reflects the current state of knowledge, provides semantic and contextual data integration that fosters hypothesis testing, continually develops new and improved tools for searching and analysis, and partners with the scientific community to assure research data needs are met. Here we describe one slice of MGI relating to the development of community-wide large-scale mutagenesis and phenotyping projects and introduce ways to access and use these MGI data. References and links to additional MGI aspects are provided. PMID:28838066

  1. Beyond botany to genetic resource preservation: the S. P. Vander Kloet Vaccinium L. collections

    USDA-ARS?s Scientific Manuscript database

    Dr. S. P. Vander Kloet, botanist, traveled the world examining and obtaining specimens to redefine infrageneric taxonomic units within Vaccinium L., family Ericaceae. Besides his botanical treatises, his legacy includes herbarium voucher specimens and ex situ genetic resource collections including a...

  2. National Academies report has broad support

    USDA-ARS?s Scientific Manuscript database

    Last December, the U.S. National Academy of Sciences (NAS) Board of Agriculture and Natural Resources convened a Forum of Scientific Society Leaders on Genetically-Engineered Crops: Experiences and Prospects. Invited participants were representatives of professional scientific societies or other org...

  3. Identification and conservation of apple genetic diversity

    USDA-ARS?s Scientific Manuscript database

    The USDA-ARS National Plant Germplasm System (NPGS) maintains a vast collection of plant genetic resources that includes over 570,000 accessions representing nearly 15,000 species. This collection is dispersed amongst 17 active sites throughout the United States. The NPGS base collection at the Nati...

  4. Forest service access to and use of the Germplasm Information Network (GRIN-Global) database and security backup at the National Laboratory for Genetic Resource Preservation

    Treesearch

    B. Loth; R.P. Karrfalt

    2017-01-01

    The U.S. Department of Agriculture Forest Service (USDA FS) National Seed Laboratory (NSL) began long term seed storage for genetic conservation, in 2005, for USDA FS units and cooperators. This program requires secure storage of both seeds and the data documenting the identification of the seeds. The Agricultural Research Service (ARS) has provided both of these...

  5. Psychiatric genetic research at the National Institute of Mental Health

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Berg, K.; Mullican, C.; Maestri, N.

    For some time it has been known through the results of family, twin, and adoption studies that hereditary appears to play a significant casual role in many mental disorders, including schizophrenia, bipolar disorder, and other mood disorders, Alzheimer`s Disease, panic disorder, obsessive compulsive disorder, autism, dyslexia, and Tourette`s syndrome. The precise patterns of inheritance of these complex disorders have not been determined, nor have the relevant genes been localized or cloned. Because the genetics are complex and because there is also clearly an environmental contribution to behavior, we expect the analysis of the genetics of mental illness to be arduousmore » and not quickly resolved. There are several compelling reasons to continue to focus our attention on uncovering the genetic factors for severe mental illness. Prominent among these are the implications for better treatment of mental disorders. The National Institute of Mental Health supports a wide range of studies on psychiatric genetic research. 16 refs.« less

  6. Human neuroscience at National Institute on Drug Abuse: Implications for genetics research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gordon, H.W.

    It is becoming clear that there is a genetic component to drug abuse. Family studies, adoption studies, and critical twin studies have all pointed to some genetic vulnerability or risk factors for an individual to abuse psychoactive drugs depending on certain psychopathologies in the biological parents and/or parents` own drug use. The question for the next generation of research at the National Institute on Drug Abuse (NIDA) is to apply the rapidly developing technology in molecular genetics in an effort to determine the candidate genes contributing to the risk. 19 refs.

  7. National coal resource investigations of the United States Geological Survey

    USGS Publications Warehouse

    Wood, Gordon H.

    1977-01-01

    The objective of this report is to provide a record of some of the goals and accomplishments of the coal resource investigations of the U. S. Geological Survey for 1977. Successful completion of these goals will aid the Nation in the years ahead because proper usage of coal resource data may lessen economic displacements resulting from the energy shortage.This report is concerned only with one mineral fuel -- coal -- and only with coal resource investigations in the Geologic Division of the U. S. Geological Survey. Other divisions involved with coal or coal-related work are the Conservation, Water Resources, and Topographic Divisions. It is one of a series of reports on the energy resource studies conducted by the Geological Survey that provide a public record of the objectives, activities, and accomplishments of these programs. Similar reports have been prepared on oil and gas, oil shale, uranium, thorium, and energy-related industrial minerals.This report includes descriptions of the program, each sub-element of the program, individual projects, and a selected list of program publications from 1970-76. It also describes how the program is responsive to Presidential pronouncements and Congressional mandates. The program is cooperative with several Federal bureaus, many state agencies, universities, and industry. This coordination assures that the program supplements the work of these interested groups and is not duplicative.A scientific program such as the coal resource investigations is difficult for the non-involved person to understand solely from the existing reports on various studies made in the program. This report provides an explanation that the scientist, decision maker, personnel of other government agencies, and the layman can use to relate various activities and to gain a better understanding of the relation of coal to the Nation's requirements for energy and of the importance of a carefully planned program on this energy resource.

  8. Linking global scenarios to national assessments: Experiences from the Resources Planning Act (RPA) Assessment

    Treesearch

    Linda L. Langner; Peter J. Ince

    2012-01-01

    The Resources Planning Act (RPA) Assessment provides a nationally consistent analysis of the status and trends of the Nation's renewable forest resources. A global scenario approach was taken for the 2010 RPA Assessment to provide a shared world view of potential futures. The RPA Assessment scenarios were linked to the global scenarios and climate projections used...

  9. A Mesoamerican origin of cherimoya (Annona cherimola Mill.): Implications for the conservation of plant genetic resources.

    PubMed

    Larranaga, N; Albertazzi, F J; Fontecha, G; Palmieri, M; Rainer, H; van Zonneveld, M; Hormaza, J I

    2017-08-01

    Knowledge on the structure and distribution of genetic diversity is a key aspect to plan and execute an efficient conservation and utilization of the genetic resources of any crop as well as for determining historical demographic inferences. In this work, a large data set of 1,765 accessions of cherimoya (Annona cherimola Mill, Annonaceae), an underutilized fruit tree crop native to the Neotropics and used as a food source by pre-Columbian cultures, was collected from six different countries across the American continent and amplified with nine highly informative microsatellite markers. The structure analyses, fine representation of the genetic diversity and an ABC approach suggest a Mesoamerican origin of the crop, contrary to previous reports, with clear implications for the dispersion of plant germplasm between Central and South America in pre-Columbian times. These results together with the potential distribution of the species in a climatic change context using two different climate models provide new insights for the history and conservation of extant genetic resources of cherimoya that can be applied to other currently underutilized woody perennial crops. © 2017 John Wiley & Sons Ltd.

  10. Facial Plastic Surgery Patient Resources Exceed National Institute Recommendations.

    PubMed

    Chu, Michael W; Cook, Julia A; Tholpady, Sunil S; Schmalbach, Cecelia E; Momeni, Arash

    2017-05-01

    Patient education is essential in enhancing the physician-patient therapeutic alliance, patient satisfaction, and clinical outcomes. The American Medical Association and National Institute of Health recommend that information be written at a 6th-grade reading level, but online resources often exceed patient literacy. The purpose of this study is to assess readability of online material for facial plastics procedures presented on academic plastic surgery and otolaryngology websites.An Internet search was performed of all academic institutions that had both plastic surgery and otolaryngology training programs who offered patient information on facial plastic surgery procedures. National society websites for both plastic surgery and otolaryngology were also analyzed. All procedural information was compiled and readability analyses were performed. A 2-tailed Z-test was used to compare scores, and statistical significance was set at P < 0.05.Sixty-three programs were identified; 42 had educational material. The overall average readability for all information was at a 10th-grade reading level. The national plastic surgery website had a significantly higher word count and number of syllables per word compared to the national otolaryngology website (P < 0.001, P = 0.04).The complexity of written resources represents an obstacle to online patient education and efforts to improve readability could benefit patients seeking medical information online. Current online education materials are a potential hindrance to patient education, satisfaction, and decision making. Healthcare institutions should consider writing new materials with simpler language that would be accessible to patients.

  11. Juridical and sociocultural problems on the definition of a law concerning property, usage and access to genetic resources in Colombia.

    PubMed

    Calle, R

    1996-04-01

    The property, usage, and access to genetic resources, is today one of the primary topics in international business, as a result of the strategic importance of the resources for the biotechnology industry. Internationally, the sovereignty that each country has over its natural patrimony is recognized. However, the new laws of international marketing have obligated countries in the process of development, such as Colombia, to adopt and copy a concept of intellectual property on living resources that does not have anything to do with the country's sociocultural identity, and sometimes even does not take into account its material enjoyment. The new juridical movement that treats genetic resources as private property produces a cultural conflict between indigenous populations, Afro-Americans and peasants, because for them the genetic resources are an element of community life. In these communities, knowledge is freely transmitted; it is an understanding that they have to conserve their agricultural customs and the relationship that they have with the environment. They do not recognize the term "property' according to patenting laws. These elements have to be considered, respected, and guaranteed in the laws that recognize the genetic resources in the country. On the other hand, not even countries that are pioneers in biotechnological development can adopt a concept about patents that is in agreement with the particularities that the living materials possess. This is obviously the reason for the numerous discussions on the legal interpretation, as well as complicated debates in court. Confronting that situation, there are countries rich in biodiversity, such as Colombia, but which do not have a proper concept and are not economically strong in the international context. These countries have to copy inadequate protection policies that do not take into account all their rights. This paper describes some of the technical, juridical, and sociocultural difficulties which

  12. Idaho National Laboratory Cultural Resource Management Annual Report FY 2006

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Clayton F. Marler; Julie Braun; Hollie Gilbert

    2007-04-01

    The Idaho National Laboratory Site is home to vast numbers and a wide variety of important cultural resources representing at least a 13,500-year span of human occupation in the region. As a federal agency, the Department of Energy Idaho Operations Office has legal responsibility for the management and protection of those resources and has delegated these responsibilities to its primary contractor, Battelle Energy Alliance (BEA). The INL Cultural Resource Management Office, staffed by BEA professionals, is committed to maintaining a cultural resource management program that accepts these challenges in a manner reflecting the resources’ importance in local, regional, and nationalmore » history. This annual report summarizes activities performed by the INL Cultural Resource Management Office staff during Fiscal Year 2006. This work is diverse, far-reaching and though generally confined to INL cultural resource compliance, also includes a myriad of professional and voluntary community activities. This document is intended to be both informative to internal and external stakeholders, and to serve as a planning tool for future cultural resource management work to be conducted on the INL.« less

  13. [National health resources for highly specialised medicine].

    PubMed

    Bratlid, Dag; Rasmussen, Knut

    2005-11-03

    In order to monitor quality and efficiency in the use of health resources for highly specialised medicine, a National Professional Council has since 1990 advised the Norwegian health authorities on the establishing and localisation of such services. A comprehensive review of both the quality, economy and the geographical distribution of patients in each specialised service has been carried out. 33 defined national programmes were centralised to one hospital only and distributed among seven university hospitals. Eight multiregional programmes were centralised to two hospitals only and included four university hospitals. In 2001, a total of 2711 new patients were treated in these programmes. The system seems to have secured a sufficient patient flow to each programme so as to maintain quality. However, a geographically skewed distribution of patients was noted, particularly in some of the national programmes. In a small country like Norway, with 4.5 million inhabitants, a centralised monitoring of highly specialised medicine seems both rational and successful. By the same logic, however, international cooperation should probably be sought for the smallest patient groups.

  14. Germplasm morgue or gold mine? Enhancing the value of plant genetic resource collections for plant breeding

    USDA-ARS?s Scientific Manuscript database

    Genetic diversity is the raw material that plant breeders require to develop cultivars that are productive, nutritious, pest and stress tolerant, and water and nutrient use efficient. The USDA-ARS National Plant Germplasm System (NPGS) contains a wealth of genetic diversity, including improved varie...

  15. African Indigenous Cattle: Unique Genetic Resources in a Rapidly Changing World

    PubMed Central

    Mwai, Okeyo; Hanotte, Olivier; Kwon, Young-Jun; Cho, Seoae

    2015-01-01

    At least 150 indigenous African cattle breeds have been named, but the majority of African cattle populations remain largely uncharacterized. As cattle breeds and populations in Africa adapted to various local environmental conditions, they acquired unique features. We know now that the history of African cattle was particularly complex and while several of its episodes remain debated, there is no doubt that African cattle population evolved dramatically over time. Today, we find a mosaic of genetically diverse population from the purest Bos taurus to the nearly pure Bos indicus. African cattle are now found all across the continent, with the exception of the Sahara and the river Congo basin. They are found on the rift valley highlands as well as below sea level in the Afar depression. These unique livestock genetic resources are in danger to disappear rapidly following uncontrolled crossbreeding and breed replacements with exotic breeds. Breeding improvement programs of African indigenous livestock remain too few while paradoxically the demand of livestock products is continually increasing. Many African indigenous breeds are endangered now, and their unique adaptive traits may be lost forever. This paper reviews the unique known characteristics of indigenous African cattle populations while describing the opportunities, the necessity and urgency to understand and utilize these resources to respond to the needs of the people of the continent and to the benefit of African farmers. PMID:26104394

  16. [Key content and formulation of national Chinese materia medica resources survey at county level].

    PubMed

    Lu, Jian-Wei; Zhang, Xiao-Bo; Li, Hai-Tao; Guo, Lan-Ping; Zhao, Run-Huai; Zhang, Ben-Gang; Sun, Li-Ying; Huang, Lu-Qi

    2013-08-01

    According to National Census for Water, National Population Census, National Land and Resources Survey, and work experience of experimental measures for national Chinese materia medica resources(CMMR) survey,the national CMMR survey at the county level is the key point of whole survey, that includes organization and management, field survey, sorting data three key links. Organization and management works of national CMMR survey needs to finish four key contents, there are definite goals and tasks, practicable crew, preparation directory, and security assurance. Field survey works of the national CMMR survey needs to finish five key contents, there are preparation works for field survey, the choice of the key survey area (samples), fill in the questionnaire, video data collection, specimen and other physical collection. Sorting data works of the national CMMR survey needs to finish tree key contents, there are data, specimen and census results.

  17. Funding of Geosciences: Coordinating National and International Resources

    NASA Astrophysics Data System (ADS)

    Bye, B.; Fontaine, K. S.

    2012-12-01

    Funding is an important element of national as well as international policy for Earth observations. The Group on Earth Observations (GEO) is coordinating efforts to build a Global Earth Observation System of Systems, or GEOSS. The lack of dedicated funding to support specific S&T activities in support of GEOSS is one of the most important obstacles to engaging the S&T communities in its implementation. This problem can be addressed by establishing explicit linkages between research and development programmes funded by GEO Members and Participating Organizations and GEOSS. In appropriate funding programs, these links may take the form of requiring explanations of how projects to be funded will interface with GEOSS and ensuring that demonstrating significant relevance for GEOSS is viewed as an asset of these proposals, requiring registration of Earth observing systems developed in these projects, or stipulating that data and products must adhere to the GEOSS Data Sharing Principles. Examples of Earth observations include: - Measurements from ground-based, in situ monitors; - Observations from Earth satellites; - Products and predictive capabilities from Earth system models, often using the capabilities of high-performance computers; - Scientific knowledge about the Earth system; and, - Data visualization techniques. These examples of Earth observations activities requires different types of resources, R&D top-down, bottom-up funding and programs of various sizes. Where innovation and infrastructure are involved different kind of resources are better suited, for developing countries completely other sources of funding are applicable etc. The European Commission funded Egida project is coordinating the development of a funding mechanism based on current national and international funding instruments such as the European ERANet, the new Joint Programming Initiatives, ESFRI as well as other European and non-European instruments. A general introduction to various

  18. The National Institute of Diabetes and Digestive and Kidney Diseases Central Repositories: A Valuable Resource for Nephrology Research

    PubMed Central

    Akolkar, Beena; Spain, Lisa M.; Guill, Michael H.; Del Vecchio, Corey T.; Carroll, Leslie E.

    2015-01-01

    The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Central Repositories, part of the National Institutes of Health (NIH), are an important resource available to researchers and the general public. The Central Repositories house samples, genetic data, phenotypic data, and study documentation from >100 NIDDK-funded clinical studies, in areas such as diabetes, digestive disease, and liver disease research. The Central Repositories also have an exceptionally rich collection of studies related to kidney disease, including the Modification of Diet in Renal Disease landmark study and recent data from the Chronic Renal Insufficiency Cohort and CKD in Children Cohort studies. The data are carefully curated and linked to the samples from the study. The NIDDK is working to make the materials and data accessible to researchers. The Data Repositories continue to improve flexible online searching tools that help researchers identify the samples or data of interest, and NIDDK has created several different paths to access the data and samples, including some funding initiatives. Over the past several years, the Central Repositories have seen steadily increasing interest and use of the stored materials. NIDDK plans to make more collections available and do more outreach and education about use of the datasets to the nephrology research community in the future to enhance the value of this resource. PMID:25376765

  19. The National Institute of Diabetes and Digestive and Kidney Diseases Central Repositories: a valuable resource for nephrology research.

    PubMed

    Rasooly, Rebekah S; Akolkar, Beena; Spain, Lisa M; Guill, Michael H; Del Vecchio, Corey T; Carroll, Leslie E

    2015-04-07

    The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Central Repositories, part of the National Institutes of Health (NIH), are an important resource available to researchers and the general public. The Central Repositories house samples, genetic data, phenotypic data, and study documentation from >100 NIDDK-funded clinical studies, in areas such as diabetes, digestive disease, and liver disease research. The Central Repositories also have an exceptionally rich collection of studies related to kidney disease, including the Modification of Diet in Renal Disease landmark study and recent data from the Chronic Renal Insufficiency Cohort and CKD in Children Cohort studies. The data are carefully curated and linked to the samples from the study. The NIDDK is working to make the materials and data accessible to researchers. The Data Repositories continue to improve flexible online searching tools that help researchers identify the samples or data of interest, and NIDDK has created several different paths to access the data and samples, including some funding initiatives. Over the past several years, the Central Repositories have seen steadily increasing interest and use of the stored materials. NIDDK plans to make more collections available and do more outreach and education about use of the datasets to the nephrology research community in the future to enhance the value of this resource. Copyright © 2015 by the American Society of Nephrology.

  20. Mineral resource appraisal of the Salmon National Forest, Idaho

    USGS Publications Warehouse

    Johnson, Rick; Close, Terry; McHugh, Ed

    1998-01-01

    The Salmon National Forest administers 1,776,994 net acres of mountainous terrain located in east-central Idaho. Most of the Forest is in Lemhi County; only a small portion falls within Idaho and Valley Counties. Approximately 426,114 acres of the Frank Church-River of No Return Wilderness extends into the western part of the Forest and mineral entry is severely restricted. Because of its location within the Salmon River drainage, the Forest also is subject to numerous issues surrounding restoration of anadromous fish runs. Mineral production from the Salmon National Forest began during 1866 when placer gold was discovered in Leesburg Basin. Hardrock mining quickly spread throughout the Forest and many deposits containing a wide range of commodities were discovered and developed. Although early records are sketchy, production is estimated to include 940,000 ounces gold, 654,000 ounces silver, 61.9 million pounds copper, 8.9 million pounds lead, 13.9 million pounds cobalt, 208,000 pounds zinc, and 37,000 tons fluorite mill feed. Mineral resources are large, diverse, and occur in many deposit types including exhalative, stockwork, disseminated, vein, replacement, sedimentary, skarn, breccia pipe, porphyry, and placer. The largest cobalt resource in the United States occurs in the Blackbird Mining District. Other resources include gold, silver, copper, lead, molybdenum, phosphate, manganese, iron, fluorite, uranium, thorium, rare earth oxides, and barite.

  1. Plant Genome Resources at the National Center for Biotechnology Information

    PubMed Central

    Wheeler, David L.; Smith-White, Brian; Chetvernin, Vyacheslav; Resenchuk, Sergei; Dombrowski, Susan M.; Pechous, Steven W.; Tatusova, Tatiana; Ostell, James

    2005-01-01

    The National Center for Biotechnology Information (NCBI) integrates data from more than 20 biological databases through a flexible search and retrieval system called Entrez. A core Entrez database, Entrez Nucleotide, includes GenBank and is tightly linked to the NCBI Taxonomy database, the Entrez Protein database, and the scientific literature in PubMed. A suite of more specialized databases for genomes, genes, gene families, gene expression, gene variation, and protein domains dovetails with the core databases to make Entrez a powerful system for genomic research. Linked to the full range of Entrez databases is the NCBI Map Viewer, which displays aligned genetic, physical, and sequence maps for eukaryotic genomes including those of many plants. A specialized plant query page allow maps from all plant genomes covered by the Map Viewer to be searched in tandem to produce a display of aligned maps from several species. PlantBLAST searches against the sequences shown in the Map Viewer allow BLAST alignments to be viewed within a genomic context. In addition, precomputed sequence similarities, such as those for proteins offered by BLAST Link, enable fluid navigation from unannotated to annotated sequences, quickening the pace of discovery. NCBI Web pages for plants, such as Plant Genome Central, complete the system by providing centralized access to NCBI's genomic resources as well as links to organism-specific Web pages beyond NCBI. PMID:16010002

  2. National Aquatic Resource Surveys: Multiple objectives and constraints lead to design complexity

    EPA Science Inventory

    The US Environmental Protection Agency began conducting the National Aquatic resource Surveys (NARS) in 2007 with a national survey of lakes (NLA 2007) followed by rivers and streams in 2008-9 (NRSA 2008), coastal waters in 2010 (NCCA 2010) and wetlands in 2011 (NWCA). The surve...

  3. The Israeli National Genetic database: a 10-year experience.

    PubMed

    Zlotogora, Joël; Patrinos, George P

    2017-03-16

    The Israeli National and Ethnic Mutation database ( http://server.goldenhelix.org/israeli ) was launched in September 2006 on the ETHNOS software to include clinically relevant genomic variants reported among Jewish and Arab Israeli patients. In 2016, the database was reviewed and corrected according to ClinVar ( https://www.ncbi.nlm.nih.gov/clinvar ) and ExAC ( http://exac.broadinstitute.org ) database entries. The present article summarizes some key aspects from the development and continuous update of the database over a 10-year period, which could serve as a paradigm of successful database curation for other similar resources. In September 2016, there were 2444 entries in the database, 890 among Jews, 1376 among Israeli Arabs, and 178 entries among Palestinian Arabs, corresponding to an ~4× data content increase compared to when originally launched. While the Israeli Arab population is much smaller than the Jewish population, the number of pathogenic variants causing recessive disorders reported in the database is higher among Arabs (934) than among Jews (648). Nevertheless, the number of pathogenic variants classified as founder mutations in the database is smaller among Arabs (175) than among Jews (192). In 2016, the entire database content was compared to that of other databases such as ClinVar and ExAC. We show that a significant difference in the percentage of pathogenic variants from the Israeli genetic database that were present in ExAC was observed between the Jewish population (31.8%) and the Israeli Arab population (20.6%). The Israeli genetic database was launched in 2006 on the ETHNOS software and is available online ever since. It allows querying the database according to the disorder and the ethnicity; however, many other features are not available, in particular the possibility to search according to the name of the gene. In addition, due to the technical limitations of the previous ETHNOS software, new features and data are not included in the

  4. Genetic Testing in Clinical Settings.

    PubMed

    Franceschini, Nora; Frick, Amber; Kopp, Jeffrey B

    2018-04-11

    Genetic testing is used for screening, diagnosis, and prognosis of diseases consistent with a genetic cause and to guide drug therapy to improve drug efficacy and avoid adverse effects (pharmacogenomics). This In Practice review aims to inform about DNA-related genetic test availability, interpretation, and recommended clinical actions based on results using evidence from clinical guidelines, when available. We discuss challenges that limit the widespread use of genetic information in the clinical care setting, including a small number of actionable genetic variants with strong evidence of clinical validity and utility, and the need for improving the health literacy of health care providers and the public, including for direct-to-consumer tests. Ethical, legal, and social issues and incidental findings also need to be addressed. Because our understanding of genetic factors associated with disease and drug response is rapidly increasing and new genetic tests are being developed that could be adopted by clinicians in the short term, we also provide extensive resources for information and education on genetic testing. Copyright © 2018 National Kidney Foundation, Inc. All rights reserved.

  5. Chemical considerations for an updated National assessment of brackish groundwater resources

    USGS Publications Warehouse

    McMahon, Peter B.; Böhlke, John Karl; Dahm, Katharine; Parkhurst, David L.; Anning, David W.; Stanton, Jennifer S.

    2016-01-01

    Brackish groundwater (BGW) is increasingly used for water supplies where fresh water is scarce, but the distribution and availability of such resources have not been characterized at the national scale in the United States since the 1960s. Apart from its distribution and accessibility, BGW usability is a function of the chemical requirements of the intended use, chemical characteristics of the resource, and treatment options to make the resource compatible with the use. Here, we discuss relations between these three chemical factors using national-scale examples and local case studies. In a preliminary compilation of BGW data in the United States, five water types accounted for the major-ion composition of 70% of samples. PHREEQC calculations indicate that 57–77% of samples were oversaturated with respect to barite, calcite, or chalcedony. In the study, 5–14% of samples had concentrations of arsenic, fluoride, nitrate, or uranium that exceeded drinking-water standards. In case studies of the potential use of BGW for drinking water, irrigation, and hydraulic fracturing, PHREEQC simulations of a hypothetical treatment process resembling reverse osmosis (RO) showed that BGW had the potential to form various assemblages of mineral deposits (scale) during treatment that could adversely affect RO membranes. Speciation calculations showed that most boron in the irrigation example occurred as boric acid, which has relatively low removal efficiency by RO. Results of this preliminary study indicate that effective national or regional assessments of BGW resources should include geochemical characterizations that are guided in part by specific use and treatment requirements.

  6. National Laboratory Planning: Developing Sustainable Biocontainment Laboratories in Limited Resource Areas.

    PubMed

    Yeh, Kenneth B; Adams, Martin; Stamper, Paul D; Dasgupta, Debanjana; Hewson, Roger; Buck, Charles D; Richards, Allen L; Hay, John

    2016-01-01

    Strategic laboratory planning in limited resource areas is essential for addressing global health security issues. Establishing a national reference laboratory, especially one with BSL-3 or -4 biocontainment facilities, requires a heavy investment of resources, a multisectoral approach, and commitments from multiple stakeholders. We make the case for donor organizations and recipient partners to develop a comprehensive laboratory operations roadmap that addresses factors such as mission and roles, engaging national and political support, securing financial support, defining stakeholder involvement, fostering partnerships, and building trust. Successful development occurred with projects in African countries and in Azerbaijan, where strong leadership and a clear management framework have been key to success. A clearly identified and agreed management framework facilitate identifying the responsibility for developing laboratory capabilities and support services, including biosafety and biosecurity, quality assurance, equipment maintenance, supply chain establishment, staff certification and training, retention of human resources, and sustainable operating revenue. These capabilities and support services pose rate-limiting yet necessary challenges. Laboratory capabilities depend on mission and role, as determined by all stakeholders, and demonstrate the need for relevant metrics to monitor the success of the laboratory, including support for internal and external audits. Our analysis concludes that alternative frameworks for success exist for developing and implementing capabilities at regional and national levels in limited resource areas. Thus, achieving a balance for standardizing practices between local procedures and accepted international standards is a prerequisite for integrating new facilities into a country's existing public health infrastructure and into the overall international scientific community.

  7. National Laboratory Planning: Developing Sustainable Biocontainment Laboratories in Limited Resource Areas

    PubMed Central

    Adams, Martin; Stamper, Paul D.; Dasgupta, Debanjana; Hewson, Roger; Buck, Charles D.; Richards, Allen L.; Hay, John

    2016-01-01

    Strategic laboratory planning in limited resource areas is essential for addressing global health security issues. Establishing a national reference laboratory, especially one with BSL-3 or -4 biocontainment facilities, requires a heavy investment of resources, a multisectoral approach, and commitments from multiple stakeholders. We make the case for donor organizations and recipient partners to develop a comprehensive laboratory operations roadmap that addresses factors such as mission and roles, engaging national and political support, securing financial support, defining stakeholder involvement, fostering partnerships, and building trust. Successful development occurred with projects in African countries and in Azerbaijan, where strong leadership and a clear management framework have been key to success. A clearly identified and agreed management framework facilitate identifying the responsibility for developing laboratory capabilities and support services, including biosafety and biosecurity, quality assurance, equipment maintenance, supply chain establishment, staff certification and training, retention of human resources, and sustainable operating revenue. These capabilities and support services pose rate-limiting yet necessary challenges. Laboratory capabilities depend on mission and role, as determined by all stakeholders, and demonstrate the need for relevant metrics to monitor the success of the laboratory, including support for internal and external audits. Our analysis concludes that alternative frameworks for success exist for developing and implementing capabilities at regional and national levels in limited resource areas. Thus, achieving a balance for standardizing practices between local procedures and accepted international standards is a prerequisite for integrating new facilities into a country's existing public health infrastructure and into the overall international scientific community. PMID:27559843

  8. Genetic management of plants in the California state parks: A primer

    Treesearch

    Deborah L. Rogers; Connie (editor) Millar

    1992-01-01

    Conservation biology, of which genetics is a major component, is receiving unprecedented attention in the management of natural resources. National fora on biological diversity, adoption by the World Bank of a strong wildland policy, and creation of new management strategies for species protection in our national parks all attest to the growing acceptance and...

  9. COTIP: Cotton TILLING Platform, a Resource for Plant Improvement and Reverse Genetic Studies

    PubMed Central

    Aslam, Usman; Cheema, Hafiza M. N.; Ahmad, Sheraz; Khan, Iqrar A.; Malik, Waqas; Khan, Asif A.

    2016-01-01

    Cotton is cultivated worldwide for its white fiber, of which around 90% is tetraploid upland cotton (Gossypium hirsutum L.) carrying both A and D genome. Since centuries, yield increasing efforts for the cotton crop by conventional breeding approaches have caused an extensive erosion of natural genetic variability. Mutation based improvement strategies provide an effective way of creating new allelic variations. Targeting Induced Local Lesions IN Genomes (TILLING) provides a mutation based reverse genetic strategy to create and evaluate induced genetic variability at DNA level. Here, we report development and testing of TILLING populations of allotetraploid cotton (G. hirsutum) for functional genomic studies and mutation based enrichment of cotton genetic resources. Seed of two cotton cultivars “PB-899 and PB-900” were mutagenized with 0.3 and 0.2% (v/v) ethyl methanesulfonate, respectively. The phenotyping of M1 and M2 populations presented numerous mutants regarding the branching pattern, leaf morphology, disease resistance, photosynthetic lesions and flower sterility. Molecular screening for point mutations was performed by TILLING PCR aided CEL1 mismatch cleavage. To estimate the mutation frequency in the mutant genomes, five gene classes were TILLed in 8000 M2 plants of each var. “PB-899” and “PB-900.” These include actin (GhACT), Pectin Methyl Esterase (GhPME), sucrose synthase (GhSUS), resistance gene analog, and defense response gene (DRGs). The var. PB-899 was harboring 47% higher mutation induction rate than PB-900. The highest rate of mutation frequency was identified for NAC-TF5 (EU706348) of DRGs class, ranging from 1/58 kb in PB-899 to 1/105 kb in PB-900. The mutation screening assay revealed the presence of significant proportion of induced mutations in cotton TILLING populations such as 1/153 kb and 1/326 kb in var. “PB-899” and “PB-900,” respectively. The establishment of a cotton TILLING platform (COTIP) and data obtained from

  10. MGIS: managing banana (Musa spp.) genetic resources information and high-throughput genotyping data

    PubMed Central

    Guignon, V.; Sempere, G.; Sardos, J.; Hueber, Y.; Duvergey, H.; Andrieu, A.; Chase, R.; Jenny, C.; Hazekamp, T.; Irish, B.; Jelali, K.; Adeka, J.; Ayala-Silva, T.; Chao, C.P.; Daniells, J.; Dowiya, B.; Effa effa, B.; Gueco, L.; Herradura, L.; Ibobondji, L.; Kempenaers, E.; Kilangi, J.; Muhangi, S.; Ngo Xuan, P.; Paofa, J.; Pavis, C.; Thiemele, D.; Tossou, C.; Sandoval, J.; Sutanto, A.; Vangu Paka, G.; Yi, G.; Van den houwe, I.; Roux, N.

    2017-01-01

    Abstract Unraveling the genetic diversity held in genebanks on a large scale is underway, due to advances in Next-generation sequence (NGS) based technologies that produce high-density genetic markers for a large number of samples at low cost. Genebank users should be in a position to identify and select germplasm from the global genepool based on a combination of passport, genotypic and phenotypic data. To facilitate this, a new generation of information systems is being designed to efficiently handle data and link it with other external resources such as genome or breeding databases. The Musa Germplasm Information System (MGIS), the database for global ex situ-held banana genetic resources, has been developed to address those needs in a user-friendly way. In developing MGIS, we selected a generic database schema (Chado), the robust content management system Drupal for the user interface, and Tripal, a set of Drupal modules which links the Chado schema to Drupal. MGIS allows germplasm collection examination, accession browsing, advanced search functions, and germplasm orders. Additionally, we developed unique graphical interfaces to compare accessions and to explore them based on their taxonomic information. Accession-based data has been enriched with publications, genotyping studies and associated genotyping datasets reporting on germplasm use. Finally, an interoperability layer has been implemented to facilitate the link with complementary databases like the Banana Genome Hub and the MusaBase breeding database. Database URL: https://www.crop-diversity.org/mgis/ PMID:29220435

  11. The Population Reference Sample, POPRES: A Resource for Population, Disease, and Pharmacological Genetics Research

    PubMed Central

    Nelson, Matthew R.; Bryc, Katarzyna; King, Karen S.; Indap, Amit; Boyko, Adam R.; Novembre, John; Briley, Linda P.; Maruyama, Yuka; Waterworth, Dawn M.; Waeber, Gérard; Vollenweider, Peter; Oksenberg, Jorge R.; Hauser, Stephen L.; Stirnadel, Heide A.; Kooner, Jaspal S.; Chambers, John C.; Jones, Brendan; Mooser, Vincent; Bustamante, Carlos D.; Roses, Allen D.; Burns, Daniel K.; Ehm, Margaret G.; Lai, Eric H.

    2008-01-01

    Technological and scientific advances, stemming in large part from the Human Genome and HapMap projects, have made large-scale, genome-wide investigations feasible and cost effective. These advances have the potential to dramatically impact drug discovery and development by identifying genetic factors that contribute to variation in disease risk as well as drug pharmacokinetics, treatment efficacy, and adverse drug reactions. In spite of the technological advancements, successful application in biomedical research would be limited without access to suitable sample collections. To facilitate exploratory genetics research, we have assembled a DNA resource from a large number of subjects participating in multiple studies throughout the world. This growing resource was initially genotyped with a commercially available genome-wide 500,000 single-nucleotide polymorphism panel. This project includes nearly 6,000 subjects of African-American, East Asian, South Asian, Mexican, and European origin. Seven informative axes of variation identified via principal-component analysis (PCA) of these data confirm the overall integrity of the data and highlight important features of the genetic structure of diverse populations. The potential value of such extensively genotyped collections is illustrated by selection of genetically matched population controls in a genome-wide analysis of abacavir-associated hypersensitivity reaction. We find that matching based on country of origin, identity-by-state distance, and multidimensional PCA do similarly well to control the type I error rate. The genotype and demographic data from this reference sample are freely available through the NCBI database of Genotypes and Phenotypes (dbGaP). PMID:18760391

  12. National Archives and Records Service Resources for the Study of Native Americans.

    ERIC Educational Resources Information Center

    Grim, Ronald E.

    Serving as an introduction to the various resources currently available in the National Archives and Records Service for geographic study of Native Americans, this paper describes the arrangement of National Archives records, identifies the major records pertaining to Native Americans, and presents an annotated bibliography of pertinent published…

  13. Molecular markers: a potential resource for ginger genetic diversity studies.

    PubMed

    Ismail, Nor Asiah; Rafii, M Y; Mahmud, T M M; Hanafi, M M; Miah, Gous

    2016-12-01

    Ginger is an economically important and valuable plant around the world. Ginger is used as a food, spice, condiment, medicine and ornament. There is available information on biochemical aspects of ginger, but few studies have been reported on its molecular aspects. The main objective of this review is to accumulate the available molecular marker information and its application in diverse ginger studies. This review article was prepared by combing material from published articles and our own research. Molecular markers allow the identification and characterization of plant genotypes through direct access to hereditary material. In crop species, molecular markers are applied in different aspects and are useful in breeding programs. In ginger, molecular markers are commonly used to identify genetic variation and classify the relatedness among varieties, accessions, and species. Consequently, it provides important input in determining resourceful management strategies for ginger improvement programs. Alternatively, a molecular marker could function as a harmonizing tool for documenting species. This review highlights the application of molecular markers (isozyme, RAPD, AFLP, SSR, ISSR and others such as RFLP, SCAR, NBS and SNP) in genetic diversity studies of ginger species. Some insights on the advantages of the markers are discussed. The detection of genetic variation among promising cultivars of ginger has significance for ginger improvement programs. This update of recent literature will help researchers and students select the appropriate molecular markers for ginger-related research.

  14. National Estimates of Genetic Testing in Women With a History of Breast or Ovarian Cancer.

    PubMed

    Childers, Christopher P; Childers, Kimberly K; Maggard-Gibbons, Melinda; Macinko, James

    2017-12-01

    Purpose In the United States, 3.8 million women have a history of breast (BC) or ovarian cancer (OC). Up to 15% of cases are attributable to heritable mutations, which, if identified, provide critical knowledge for treatment and preventive care. It is unknown how many patients who are at high risk for these mutations have not been tested and how rates vary by risk criteria. Methods We used pooled cross-sectional data from three Cancer Control Modules (2005, 2010, 2015) of the National Health Interview Survey, a national in-person household interview survey. Eligible patients were adult females with a history of BC and/or OC meeting select 2017 National Comprehensive Cancer Network eligibility criteria on the basis of age of diagnosis and family history. Outcomes included the proportion of individuals reporting a history of discussing genetic testing with a health professional, being advised to undergo genetic testing, or undergoing genetic testing for BC or OC. Results Of 47,218 women, 2.7% had a BC history and 0.4% had an OC history. For BC, 35.6% met one or more select eligibility criteria; of those, 29.0% discussed, 20.2% were advised to undergo, and 15.3% underwent genetic testing. Testing rates for individual eligibility criteria ranged from 6.2% (relative with OC) to 18.2% (diagnosis ≤ 45 years of age). For OC, 15.1% discussed, 13.1% were advised to undergo, and 10.5% underwent testing. Using only four BC eligibility criteria and all patients with OC, an estimated 1.2 to 1.3 million individuals failed to receive testing. Conclusion Fewer than one in five individuals with a history of BC or OC meeting select National Cancer Comprehensive Network criteria have undergone genetic testing. Most have never discussed testing with a health care provider. Large national efforts are warranted to address this unmet need.

  15. Environmental resource document for the Idaho National Engineering Laboratory. Volume 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Irving, J.S.

    This document contains information related to the environmental characterization of the Idaho National Engineering Laboratory (INEL). The INEL is a major US Department of Energy facility in southeastern Idaho dedicated to nuclear research, waste management, environmental restoration, and other activities related to the development of technology. Environmental information covered in this document includes land, air, water, and ecological resources; socioeconomic characteristics and land use; and cultural, aesthetic, and scenic resources.

  16. Improved methods for national water assessment, water resources contract: WR15249270

    USGS Publications Warehouse

    Thomas, Harold A.

    1981-01-01

    The purpose of our research is to develop methods to make National Water Assessment more useful in estimating water availability for economic growth and more helpful in determining the effect of water resource development upon the environmental quality of related land resources. There are serious questions pertaining to the 1975 Water Assessment and these amplify the significance of decisions made as to the planning and scheduling of the next assessment.

  17. Information Avoidance Tendencies, Threat Management Resources, and Interest in Genetic Sequencing Feedback.

    PubMed

    Taber, Jennifer M; Klein, William M P; Ferrer, Rebecca A; Lewis, Katie L; Harris, Peter R; Shepperd, James A; Biesecker, Leslie G

    2015-08-01

    Information avoidance is a defensive strategy that undermines receipt of potentially beneficial but threatening health information and may especially occur when threat management resources are unavailable. We examined whether individual differences in information avoidance predicted intentions to receive genetic sequencing results for preventable and unpreventable (i.e., more threatening) disease and, secondarily, whether threat management resources of self-affirmation or optimism mitigated any effects. Participants (N = 493) in an NIH study (ClinSeq®) piloting the use of genome sequencing reported intentions to receive (optional) sequencing results and completed individual difference measures of information avoidance, self-affirmation, and optimism. Information avoidance tendencies corresponded with lower intentions to learn results, particularly for unpreventable diseases. The association was weaker among individuals higher in self-affirmation or optimism, but only for results regarding preventable diseases. Information avoidance tendencies may influence decisions to receive threatening health information; threat management resources hold promise for mitigating this association.

  18. 76 FR 21404 - National Park Service Alaska Region's Subsistence Resource Commission (SRC) Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ... Resource Commission (SRC) program. SUMMARY: The Gates of the Arctic National Park SRC will meet to develop... to do so. Gates of the Arctic National Park SRC Meeting Date and Location: The Gates of the Arctic... weather or local circumstances. For Further Information on the Gates of the Arctic National Park SRC...

  19. The Forest Genetic Resources Working Group of the North American Forestry Commission (FAO)

    Treesearch

    Ronald C. Schmidtling

    2002-01-01

    The Forest Genetic Resources Working Group (FGRWG) is one of seven working groups established by the North American Forest Commission (NAFC). The NAFC is one of six Forest Commissions established by the Food and Agriculture Organization (F-40). The FGRWG was established by the NAFC in 1961 as the Working Group on Forest Tree Improvement but went through several-changes...

  20. Towards a joint national and state partnership in aquatic resource assessment monitoring survey design

    EPA Science Inventory

    The USEPA is currently conducting national assessments of all aquatic resources in the United States. Prior national assessments were completed for coastal waters and wadeable streams. National assessments are now underway for lakes, rivers and streams, coastal waters, and wetl...

  1. USGS Mineral Resources Program; national maps and datasets for research and land planning

    USGS Publications Warehouse

    Nicholson, S.W.; Stoeser, D.B.; Ludington, S.D.; Wilson, Frederic H.

    2001-01-01

    The U.S. Geological Survey, the Nation’s leader in producing and maintaining earth science data, serves as an advisor to Congress, the Department of the Interior, and many other Federal and State agencies. Nationwide datasets that are easily available and of high quality are critical for addressing a wide range of land-planning, resource, and environmental issues. Four types of digital databases (geological, geophysical, geochemical, and mineral occurrence) are being compiled and upgraded by the Mineral Resources Program on regional and national scales to meet these needs. Where existing data are incomplete, new data are being collected to ensure national coverage. Maps and analyses produced from these databases provide basic information essential for mineral resource assessments and environmental studies, as well as fundamental information for regional and national land-use studies. Maps and analyses produced from the databases are instrumental to ongoing basic research, such as the identification of mineral deposit origins, determination of regional background values of chemical elements with known environmental impact, and study of the relationships between toxic elements or mining practices to human health. As datasets are completed or revised, the information is made available through a variety of media, including the Internet. Much of the available information is the result of cooperative activities with State and other Federal agencies. The upgraded Mineral Resources Program datasets make geologic, geophysical, geochemical, and mineral occurrence information at the state, regional, and national scales available to members of Congress, State and Federal government agencies, researchers in academia, and the general public. The status of the Mineral Resources Program datasets is outlined below.

  2. Genetic selection and conservation of genetic diversity*.

    PubMed

    Blackburn, H D

    2012-08-01

    For 100s of years, livestock producers have employed various types of selection to alter livestock populations. Current selection strategies are little different, except our technologies for selection have become more powerful. Genetic resources at the breed level have been in and out of favour over time. These resources are the raw materials used to manipulate populations, and therefore, they are critical to the past and future success of the livestock sector. With increasing ability to rapidly change genetic composition of livestock populations, the conservation of these genetic resources becomes more critical. Globally, awareness of the need to steward genetic resources has increased. A growing number of countries have embarked on large scale conservation efforts by using in situ, ex situ (gene banking), or both approaches. Gene banking efforts have substantially increased and data suggest that gene banks are successfully capturing genetic diversity for research or industry use. It is also noteworthy that both industry and the research community are utilizing gene bank holdings. As pressures grow to meet consumer demands and potential changes in production systems, the linkage between selection goals and genetic conservation will increase as a mechanism to facilitate continued livestock sector development. © 2012 Blackwell Verlag GmbH.

  3. Strategic and tactiocal planning for managing national park resources

    Treesearch

    Daniel L. Schmoldt; David L. Peterson

    2001-01-01

    Each National Park Service unit in the United States produces a resource management plan (RMP) every four years or less. These plans constitute a strategic agenda for a park. Later, tactical plans commit budgets and personnel to specific projects over the planning horizon. Yet, neither planning stage incorporates much quantitative and analytical rigor and is devoid of...

  4. Database resources of the National Center for Biotechnology Information

    PubMed Central

    Wheeler, David L.; Church, Deanna M.; Lash, Alex E.; Leipe, Detlef D.; Madden, Thomas L.; Pontius, Joan U.; Schuler, Gregory D.; Schriml, Lynn M.; Tatusova, Tatiana A.; Wagner, Lukas; Rapp, Barbara A.

    2001-01-01

    In addition to maintaining the GenBank® nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides data analysis and retrieval resources that operate on the data in GenBank and a variety of other biological data made available through NCBI’s Web site. NCBI data retrieval resources include Entrez, PubMed, LocusLink and the Taxonomy Browser. Data analysis resources include BLAST, Electronic PCR, OrfFinder, RefSeq, UniGene, HomoloGene, Database of Single Nucleotide Polymorphisms (dbSNP), Human Genome Sequencing, Human MapViewer, GeneMap’99, Human–Mouse Homology Map, Cancer Chromosome Aberration Project (CCAP), Entrez Genomes, Clusters of Orthologous Groups (COGs) database, Retroviral Genotyping Tools, Cancer Genome Anatomy Project (CGAP), SAGEmap, Gene Expression Omnibus (GEO), Online Mendelian Inheri­tance in Man (OMIM), the Molecular Modeling Database (MMDB) and the Conserved Domain Database (CDD). Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of the resources can be accessed through the NCBI home page at: http://www.ncbi.nlm.nih.gov. PMID:11125038

  5. Assessing the quality of the nation's water resources

    USGS Publications Warehouse

    Hamilton, Pixie A.

    2002-01-01

    This issue of IMPACT highlights findings from the first decade of studies (1991 to 2001) by the National Water-Quality Assessment (NAWQA) Program of the U.S. Geological Survey (USGS). The articles also discuss the Program’s approaches and models designed to help understand and estimate the fate and transport of contaminants in different geographic areas and environmental settings and over different time frames. NAWQA was established by Congress in 1991 with a goal of developing long-term, consistent, and comparable science-based information on nationwide water-quality conditions. This information is used to support sound management and policy decisions by decision makers at all levels – local, state, and national – who, every day, face complex regulations and management issues related to water resources.

  6. The Gene Therapy Resource Program: A Decade of Dedication to Translational Research by the National Heart, Lung, and Blood Institute.

    PubMed

    Flotte, Terence R; Daniels, Eric; Benson, Janet; Bevett-Rose, Jeneé M; Cornetta, Kenneth; Diggins, Margaret; Johnston, Julie; Sepelak, Susan; van der Loo, Johannes C M; Wilson, James M; McDonald, Cheryl L

    2017-12-01

    Over a 10-year period, the Gene Therapy Resource Program (GTRP) of the National Heart Lung and Blood Institute has provided a set of core services to investigators to facilitate the clinical translation of gene therapy. These services have included a preclinical (research-grade) vector production core; current Good Manufacturing Practice clinical-grade vector cores for recombinant adeno-associated virus and lentivirus vectors; a pharmacology and toxicology core; and a coordinating center to manage program logistics and to provide regulatory and financial support to early-phase clinical trials. In addition, the GTRP has utilized a Steering Committee and a Scientific Review Board to guide overall progress and effectiveness and to evaluate individual proposals. These resources have been deployed to assist 82 investigators with 172 approved service proposals. These efforts have assisted in clinical trial implementation across a wide range of genetic, cardiac, pulmonary, and blood diseases. Program outcomes and potential future directions of the program are discussed.

  7. 76 FR 45505 - Ozark-Ouachita National Forests Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ... DEPARTMENT OF AGRICULTURE Forest Service Ozark-Ouachita National Forests Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Ozark-Ouachita RAC will meet... recommendations to the Forest Service concerning projects and funding consistent with the title II of the Act. The...

  8. National assessment of geologic carbon dioxide storage resources: methodology implementation

    USGS Publications Warehouse

    Blondes, Madalyn S.; Brennan, Sean T.; Merrill, Matthew D.; Buursink, Marc L.; Warwick, Peter D.; Cahan, Steven M.; Corum, Margo D.; Cook, Troy A.; Craddock, William H.; DeVera, Christina A.; Drake II, Ronald M.; Drew, Lawrence J.; Freeman, P.A.; Lohr, Celeste D.; Olea, Ricardo A.; Roberts-Ashby, Tina L.; Slucher, Ernie R.; Varela, Brian A.

    2013-01-01

    In response to the 2007 Energy Independence and Security Act, the U.S. Geological Survey (USGS) conducted a national assessment of potential geologic storage resources for carbon dioxide (CO2). Storage of CO2 in subsurface saline formations is one important method to reduce greenhouse gas emissions and curb global climate change. This report provides updates and implementation details of the assessment methodology of Brennan and others (2010, http://pubs.usgs.gov/of/2010/1127/) and describes the probabilistic model used to calculate potential storage resources in subsurface saline formations.

  9. The National Shipbuilding Research Program. National Workshop (4th) on Human Resource Innovation in Shipbuilding and Ship Repair

    DTIC Science & Technology

    1995-11-01

    SHIP PRODUCTION COMMITTEE FACILITIES AND ENVIRONMENTAL EFFECTS SURFACE PREPARATION AND COATINGS DESIGN/PRODUCTION INTEGRATION HUMAN RESOURCE...we’re all about. 2 Exhibit 1 NATIONAL SHIPBUILDING RESEARCH PROGRAM RESEARCH PANELS SP-1 Facilities and Environmental Effects SP-3 Surface... effectively compete in the international commercial shipbuilding market. On November 30,1993, President Clinton signed into law the National

  10. Genetic resources for maize cell wall biology.

    PubMed

    Penning, Bryan W; Hunter, Charles T; Tayengwa, Reuben; Eveland, Andrea L; Dugard, Christopher K; Olek, Anna T; Vermerris, Wilfred; Koch, Karen E; McCarty, Donald R; Davis, Mark F; Thomas, Steven R; McCann, Maureen C; Carpita, Nicholas C

    2009-12-01

    Grass species represent a major source of food, feed, and fiber crops and potential feedstocks for biofuel production. Most of the biomass is contributed by cell walls that are distinct in composition from all other flowering plants. Identifying cell wall-related genes and their functions underpins a fundamental understanding of growth and development in these species. Toward this goal, we are building a knowledge base of the maize (Zea mays) genes involved in cell wall biology, their expression profiles, and the phenotypic consequences of mutation. Over 750 maize genes were annotated and assembled into gene families predicted to function in cell wall biogenesis. Comparative genomics of maize, rice (Oryza sativa), and Arabidopsis (Arabidopsis thaliana) sequences reveal differences in gene family structure between grass species and a reference eudicot species. Analysis of transcript profile data for cell wall genes in developing maize ovaries revealed that expression within families differed by up to 100-fold. When transcriptional analyses of developing ovaries before pollination from Arabidopsis, rice, and maize were contrasted, distinct sets of cell wall genes were expressed in grasses. These differences in gene family structure and expression between Arabidopsis and the grasses underscore the requirement for a grass-specific genetic model for functional analyses. A UniformMu population proved to be an important resource in both forward- and reverse-genetics approaches to identify hundreds of mutants in cell wall genes. A forward screen of field-grown lines by near-infrared spectroscopic screen of mature leaves yielded several dozen lines with heritable spectroscopic phenotypes. Pyrolysis-molecular beam mass spectrometry confirmed that several nir mutants had altered carbohydrate-lignin compositions.

  11. The Plant Genetic Engineering Laboratory For Desert Adaptation

    NASA Astrophysics Data System (ADS)

    Kemp, John D.; Phillips, Gregory C.

    1985-11-01

    The Plant Genetic Engineering Laboratory for Desert Adaptation (PGEL) is one of five Centers of Technical Excellence established as a part of the state of New Mexico's Rio Grande Research Corridor (RGRC). The scientific mission of PGEL is to bring innovative advances in plant biotechnology to bear on agricultural productivity in arid and semi-arid regions. Research activities focus on molecular and cellular genetics technology development in model systems, but also include stress physiology investigations and development of desert plant resources. PGEL interacts with the Los Alamos National Laboratory (LANL), a national laboratory participating in the RGRC. PGEL also has an economic development mission, which is being pursued through technology transfer activities to private companies and public agencies.

  12. NATURAL RESOURCE MANAGEMENT PLAN FOR BROOKHAVEN NATIONAL LABORATORY.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    GREEN,T.ET AL.

    2003-12-31

    Brookhaven National Laboratory (BNL) is located near the geographic center of Long Island, New York. The Laboratory is situated on 5,265 acres of land composed of Pine Barrens habitat with a central area developed for Laboratory work. In the mid-1990s BNL began developing a wildlife management program. This program was guided by the Wildlife Management Plan (WMP), which was reviewed and approved by various state and federal agencies in September 1999. The WMP primarily addressed concerns with the protection of New York State threatened, endangered, or species of concern, as well as deer populations, invasive species management, and the revegetationmore » of the area surrounding the Relativistic Heavy Ion Collider (RHIC). The WMP provided a strong and sound basis for wildlife management and established a basis for forward motion and the development of this document, the Natural Resource Management Plan (NRMP), which will guide the natural resource management program for BNL. The body of this plan establishes the management goals and actions necessary for managing the natural resources at BNL. The appendices provide specific management requirements for threatened and endangered amphibians and fish (Appendices A and B respectively), lists of actions in tabular format (Appendix C), and regulatory drivers for the Natural Resource Program (Appendix D). The purpose of the Natural Resource Management Plan is to provide management guidance, promote stewardship of the natural resources found at BNL, and to integrate their protection with pursuit of the Laboratory's mission. The philosophy or guiding principles of the NRMP are stewardship, adaptive ecosystem management, compliance, integration with other plans and requirements, and incorporation of community involvement, where applicable.« less

  13. Forest resource statistics for the Monongahela National Forest: 2000

    Treesearch

    Richard H. Widmann; Douglas M. Griffith

    2004-01-01

    During 1999-2000, the fifth inventory of West Virginia?s forest resources was conducted by the Forest Inventory and Analysis unit of the USDA Forest Service?s Northeastern Research Station. The survey included a subsample within the Monongahela National Forest (MNF). The results showed that the MNF contains 899,000 acres of forest land, or 7.5 percent of the State?s...

  14. What Are Probability Surveys used by the National Aquatic Resource Surveys?

    EPA Pesticide Factsheets

    The National Aquatic Resource Surveys (NARS) use probability-survey designs to assess the condition of the nation’s waters. In probability surveys (also known as sample-surveys or statistical surveys), sampling sites are selected randomly.

  15. 75 FR 36346 - Olympic National Forest; Title II Resource Advisory Committee Meeting Advisory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ... DEPARTMENT OF AGRICULTURE Olympic National Forest; Title II Resource Advisory Committee Meeting Advisory AGENCY: Olympic National Forest, USDA Forest Service. ACTION: Notice of meeting. SUMMARY: The... this meeting will be to review project proposals and provide recommendations for Title II projects to...

  16. [Genetic Polymorphisms of 26 Y-STR Loci in Fujian She Nationality and Its Forensic Application].

    PubMed

    Bian, Ying-nan; Siyit, Tele T; Zhu, Ru-xin; Zhao, Qi; Zhang Su-hua

    2015-08-01

    To study the forensic application of Goldeneye DNA ID 26Y Kit in the She nationality. Through capillary electrophoresis, the genotype of 26 Y-STR loci were analyzed in 53 unrelated male individuals from Fujian She nationality. The population genetics parameters such as allele frequency and haplotype diversity were calculated. The comparisons among the She nationality and the other nationalities were analyzed. A total of 126 alleles were observed on the 26 Y-STR loci of 53 unrelated male individuals. The allele frequencies and GD value ranged from 0.010 1 to 0.886 8 and 0.211 2 to 0.846 2, respectively. The GD value was greater than 0.5 in the 19 loci. A total of 47 haplotypes were observed. Based on R(ST), multidimensional scaling plot indicated that the genetic relationship among Fujian She nationality and Minnan Han nationality was closest, followed by Southern China Han nationality and Northern China nationality. Goldeneye™ DNA ID 26Y Kit including 26 Y-STR loci has good polymorphism in the She nationality. As an additional system, it has forensic application value in some special cases.

  17. 75 FR 7487 - National Center for Research Resources; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research Resources; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the...

  18. 76 FR 6627 - National Center for Research Resources; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Research Resources; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the...

  19. National assessment of geologic carbon dioxide storage resources: data

    USGS Publications Warehouse

    ,

    2013-01-01

    In 2012, the U.S. Geological Survey (USGS) completed the national assessment of geologic carbon dioxide storage resources. Its data and results are reported in three publications: the assessment data publication (this report), the assessment results publication (U.S. Geological Survey Geologic Carbon Dioxide Storage Resources Assessment Team, 2013a, USGS Circular 1386), and the assessment summary publication (U.S. Geological Survey Geologic Carbon Dioxide Storage Resources Assessment Team, 2013b, USGS Fact Sheet 2013–3020). This data publication supports the results publication and contains (1) individual storage assessment unit (SAU) input data forms with all input parameters and details on the allocation of the SAU surface land area by State and general land-ownership category; (2) figures representing the distribution of all storage classes for each SAU; (3) a table containing most input data and assessment result values for each SAU; and (4) a pairwise correlation matrix specifying geological and methodological dependencies between SAUs that are needed for aggregation of results.

  20. Regulation of Genetic Tests

    MedlinePlus

    ... Informed Consent for Genomics Research Intellectual Property Online Bioethics Resources Privacy in Genomics Regulation of Genetic Tests ... Research Intellectual Property Issues in Genetics Archive Online Bioethics Resources Privacy in Genomics Regulation of Genetic Tests ...

  1. Cultural factors of visitors' understanding of United States National Park Service natural resource messages

    NASA Astrophysics Data System (ADS)

    Hilton, Sunita Claire

    Current trends in the demographic structure of the US population indicate increasing cultural diversity. Culturally-diverse populations have varying beliefs, views and understandings of natural resource use and management. This study concentrates on understanding how messages pertaining to natural resources concepts and associated management decisions are communicated to and received by culturally-diverse audiences. This is particularly relevant to land managing agencies, such as the US National Park Service (NPS), that rely on a high degree of public contact and support. Failure to consider cultural-diversity has the potential to interfere with this agency's success at communicating its mission and management decisions. The study took place in three US National Parks; Grand Canyon National Park (North Rim), Guadalupe Mountains National Park, and Hawai'i Volcanoes National Park. Visitors were asked to complete an on-site anonymous questionnaire. Data were collected at various locations including trailheads, scenic overlooks, at visitor centers, and after interpretive programs. Total number of participants was 549, Grand Canyon National Park n = 156, Guadalupe Mountains National Park n = 153, and Hawai'i Volcanoes National Park n = 240. Results indicate that visitors were knowledgeable about the resources they were visiting. Visitors to NPS sites have achieved a high level of formal education. Certain aspects of culture, religion/spirituality seem to have a greater role in how visitors identify themselves, as opposed to ethnicity/cultural heritage. However when visitors are in a park they seem display similar cultural characteristics, which may come to the forefront while in the park setting as opposed to home setting. Methodological challenges of studying culture in a national park setting are also discussed.

  2. Database resources of the National Center for Biotechnology

    PubMed Central

    Wheeler, David L.; Church, Deanna M.; Federhen, Scott; Lash, Alex E.; Madden, Thomas L.; Pontius, Joan U.; Schuler, Gregory D.; Schriml, Lynn M.; Sequeira, Edwin; Tatusova, Tatiana A.; Wagner, Lukas

    2003-01-01

    In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides data analysis and retrieval resources for the data in GenBank and other biological data made available through NCBI's Web site. NCBI resources include Entrez, PubMed, PubMed Central (PMC), LocusLink, the NCBITaxonomy Browser, BLAST, BLAST Link (BLink), Electronic PCR (e-PCR), Open Reading Frame (ORF) Finder, References Sequence (RefSeq), UniGene, HomoloGene, ProtEST, Database of Single Nucleotide Polymorphisms (dbSNP), Human/Mouse Homology Map, Cancer Chromosome Aberration Project (CCAP), Entrez Genomes and related tools, the Map Viewer, Model Maker (MM), Evidence Viewer (EV), Clusters of Orthologous Groups (COGs) database, Retroviral Genotyping Tools, SAGEmap, Gene Expression Omnibus (GEO), Online Mendelian Inheritance in Man (OMIM), the Molecular Modeling Database (MMDB), the Conserved Domain Database (CDD), and the Conserved Domain Architecture Retrieval Tool (CDART). Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of the resources can be accessed through the NCBI home page at: http://www.ncbi.nlm.nih.gov. PMID:12519941

  3. Education resources of the National Center for Biotechnology Information.

    PubMed

    Cooper, Peter S; Lipshultz, Dawn; Matten, Wayne T; McGinnis, Scott D; Pechous, Steven; Romiti, Monica L; Tao, Tao; Valjavec-Gratian, Majda; Sayers, Eric W

    2010-11-01

    The National Center for Biotechnology Information (NCBI) hosts 39 literature and molecular biology databases containing almost half a billion records. As the complexity of these data and associated resources and tools continues to expand, so does the need for educational resources to help investigators, clinicians, information specialists and the general public make use of the wealth of public data available at the NCBI. This review describes the educational resources available at NCBI via the NCBI Education page (www.ncbi.nlm.nih.gov/Education/). These resources include materials designed for new users, such as About NCBI and the NCBI Guide, as well as documentation, Frequently Asked Questions (FAQs) and writings on the NCBI Bookshelf such as the NCBI Help Manual and the NCBI Handbook. NCBI also provides teaching materials such as tutorials, problem sets and educational tools such as the Amino Acid Explorer, PSSM Viewer and Ebot. NCBI also offers training programs including the Discovery Workshops, webinars and tutorials at conferences. To help users keep up-to-date, NCBI produces the online NCBI News and offers RSS feeds and mailing lists, along with a presence on Facebook, Twitter and YouTube.

  4. Education resources of the National Center for Biotechnology Information

    PubMed Central

    Lipshultz, Dawn; Matten, Wayne T.; McGinnis, Scott D.; Pechous, Steven; Romiti, Monica L.; Tao, Tao; Valjavec-Gratian, Majda; Sayers, Eric W.

    2010-01-01

    The National Center for Biotechnology Information (NCBI) hosts 39 literature and molecular biology databases containing almost half a billion records. As the complexity of these data and associated resources and tools continues to expand, so does the need for educational resources to help investigators, clinicians, information specialists and the general public make use of the wealth of public data available at the NCBI. This review describes the educational resources available at NCBI via the NCBI Education page (www.ncbi.nlm.nih.gov/Education/). These resources include materials designed for new users, such as About NCBI and the NCBI Guide, as well as documentation, Frequently Asked Questions (FAQs) and writings on the NCBI Bookshelf such as the NCBI Help Manual and the NCBI Handbook. NCBI also provides teaching materials such as tutorials, problem sets and educational tools such as the Amino Acid Explorer, PSSM Viewer and Ebot. NCBI also offers training programs including the Discovery Workshops, webinars and tutorials at conferences. To help users keep up-to-date, NCBI produces the online NCBI News and offers RSS feeds and mailing lists, along with a presence on Facebook, Twitter and YouTube. PMID:20570844

  5. Database resources of the National Center for Biotechnology Information

    PubMed Central

    Wheeler, David L.; Barrett, Tanya; Benson, Dennis A.; Bryant, Stephen H.; Canese, Kathi; Chetvernin, Vyacheslav; Church, Deanna M.; DiCuccio, Michael; Edgar, Ron; Federhen, Scott; Feolo, Michael; Geer, Lewis Y.; Helmberg, Wolfgang; Kapustin, Yuri; Khovayko, Oleg; Landsman, David; Lipman, David J.; Madden, Thomas L.; Maglott, Donna R.; Miller, Vadim; Ostell, James; Pruitt, Kim D.; Schuler, Gregory D.; Shumway, Martin; Sequeira, Edwin; Sherry, Steven T.; Sirotkin, Karl; Souvorov, Alexandre; Starchenko, Grigory; Tatusov, Roman L.; Tatusova, Tatiana A.; Wagner, Lukas; Yaschenko, Eugene

    2008-01-01

    In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data available through NCBI's web site. NCBI resources include Entrez, the Entrez Programming Utilities, My NCBI, PubMed, PubMed Central, Entrez Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link, Electronic PCR, OrfFinder, Spidey, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, Cancer Chromosomes, Entrez Genome, Genome Project and related tools, the Trace, Assembly, and Short Read Archives, the Map Viewer, Model Maker, Evidence Viewer, Clusters of Orthologous Groups, Influenza Viral Resources, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus, Entrez Probe, GENSAT, Database of Genotype and Phenotype, Online Mendelian Inheritance in Man, Online Mendelian Inheritance in Animals, the Molecular Modeling Database, the Conserved Domain Database, the Conserved Domain Architecture Retrieval Tool and the PubChem suite of small molecule databases. Augmenting the web applications are custom implementations of the BLAST program optimized to search specialized data sets. These resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov. PMID:18045790

  6. National Research Program of the Water Resources Division, U.S. Geological Survey, fiscal year 1987

    USGS Publications Warehouse

    Friedman, Linda C.; Donato, Christine N.

    1988-01-01

    The National Research Program (NRP) of the U.S. Geological Survey's Water Resources Division (WRD) had its beginnings in the late 1950's when "core research" was added as a line item to the Congressional budget. Since that time, the NRP has grown to encompass a broad spectrum of scientific investigations. The sciences of hydrology, mathematics, chemistry, physics, biology, geology, and engineering are used to gain a fundamental understanding of the processes that affect the availability, movement, and quality of the Nation's water resources. The knowledge gained and methods developed have great value to WRD's operational program. Results of the investigations conducted by the NRP are applicable not only to the solution of current water problems, but also to future issues, anticipated or unanticipated, that may affect the Nation's water resources.

  7. National Research Program of the Water Resources Division, U. S. Geological Survey, Fiscal Year 1989

    USGS Publications Warehouse

    Eggers, JoAnn; Friedman, Linda C.

    1989-01-01

    The National Research Program (NRP) of the U.S. Geological Survey's Water Resources Division (WRD) had its beginnings in the late 1950's when "core research" was added as a line item to the Congressional budget. Since that time, the NRP has grown to encompass a broad spectrum of scientific investigations. The sciences of hydrology, mathematics, chemistry, physics, ecology, biology, geology, and engineering are used to gain a fundamental understanding of the processes that affect the availability, movement, and quality of the Nation's water resources. The knowledge gained and methods developed have great value to WRD's operational program. Results of the investigations conducted by the NRP are applicable not only to the solution of current water problems but also to future issues, anticipated or unanticipated, that may affect the Nation's water resources.

  8. Alternative Fuels Data Center: National Park Saves Natural Resources with

    Science.gov Websites

    Alternative FuelsA> National Park Saves Natural Resources with Alternative Fuels to someone by E alternative fuel vehicles. For information about this project, contact East Tennessee Clean Fuels Coalition - Television's Original Automotive Magazine Provided by Maryland Public Television Related Videos Photo of a car

  9. Biosecurity strategies for conserving valuable livestock genetic resources.

    PubMed

    Wrathall, Anthony E; Simmons, Hugh A; Bowles, Dianna J; Jones, Sam

    2004-01-01

    The foot and mouth disease (FMD) epidemic in the UK in 2001 highlighted the threat of infectious diseases to rare and valuable livestock and stimulated a renewed interest in biosecurity and conservation. However, not all diseases resemble FMD: their transmission routes and pathological effects vary greatly, so biosecurity strategies must take this into account. Realism is also needed as to which diseases to exclude and which will have to be tolerated. The aim should be to minimise disease generally and to exclude those diseases that threaten the existence of livestock or preclude their national or international movement. Achieving this requires a team effort, bearing in mind the livestock species involved, the farming system ('open' or 'closed') and the premises. Effective biosecurity demands that practically every aspect of farm life is controlled, including movements of people, vehicles, equipment, food, manure, animal carcasses and wildlife. Above all, biosecurity strategies must cover the disease risks associated with moving the livestock themselves and this will require quarantine if adult or juvenile animals are imported into the herd or flock. The present paper emphasises the important role that reproductive technologies, such as artificial insemination and embryo transfer, can have in biosecurity strategies because they offer much safer ways for getting new genetic materials into herds/flocks than bringing in live animals. Embryo transfer is especially safe when the sanitary protocols promoted by the International Embryo Transfer Society and advocated by the Office International des Epizooties (the 'World Organisation for Animal Health') are used. Embryo transfer can also allow the full genetic complement to be salvaged from infected animals. Cryobanking of genetic materials, especially embryos, is another valuable biosecurity strategy because it enables their storage for conservation in the face of contingencies, such as epidemic disease and other

  10. Valuing goat genetic resources: a pro-poor growth strategy in the Kenyan semi-arid tropics.

    PubMed

    Omondi, I A; Baltenweck, I; Drucker, A G; Obare, G A; Zander, K K

    2008-12-01

    Goats, "the poor man's cow", provide very important genetic resources that can be exploited for continued improvements of the livelihoods of poor livestock keepers in the semi-arid tropics. This study presents the evaluation of the economic values of goat genetic resources (GGRs) in terms of the important non-market traits embedded in goats and how this information can be utilised to improve livelihoods in semi-arid regions. The results obtained from mixed logit models derived from stated choice data collected from 314 respondents in the semi-arid Marsabit district of Kenya reveal that disease resistance is the most highly valued trait whose resultant augmentation results into a welfare improvement of up to KShs.2899. Drought tolerance and milk traits were found to be implicitly valued at KShs.2620 and 1179 respectively. The study further revealed that improvement in milk trait in does, body size and disease resistance traits in bucks, and drought tolerance trait in both does and bucks will collectively improve the producers' welfare hence should be given priority. However, improvement in the reproduction and production ("overall body condition/ meatiness" trait) potential of goats will be worthwhile only if issues concerning access to pasture and water resources are addressed prior and simultaneously.

  11. Applying the concept of Independent Applicability to results from the National Aquatic Resource Surveys

    EPA Science Inventory

    The assessments resulting from the National Aquatic Resource Surveys have taken the tact of basing estimates of resource condition on the biological indicators of quality. The physical habitat, chemical, hydrological, and watershed indicators are used to evaluate the relative ra...

  12. Access and benefits sharing of genetic resources and associated traditional knowledge in northern Canada: understanding the legal environment and creating effective research agreements.

    PubMed

    Geary, Janis; Jardine, Cynthia G; Guebert, Jenilee; Bubela, Tania

    2013-01-01

    Research in northern Canada focused on Aboriginal peoples has historically benefited academia with little consideration for the people being researched or their traditional knowledge (TK). Although this attitude is changing, the complexity of TK makes it difficult to develop mechanisms to preserve and protect it. Protecting TK becomes even more important when outside groups become interested in using TK or materials with associated TK. In the latter category are genetic resources, which may have commercial value and are the focus of this article. This article addresses access to and use of genetic resources and associated TK in the context of the historical power-imbalances in research relationships in Canadian north. Review. Research involving genetic resources and TK is becoming increasingly relevant in northern Canada. The legal framework related to genetic resources and the cultural shift of universities towards commercial goals in research influence the environment for negotiating research agreements. Current guidelines for research agreements do not offer appropriate guidelines to achieve mutual benefit, reflect unequal bargaining power or take the relationship between parties into account. Relational contract theory may be a useful framework to address the social, cultural and legal hurdles inherent in creating research agreements.

  13. Monitoring the condition of natural resources in US national parks.

    PubMed

    Fancy, S G; Gross, J E; Carter, S L

    2009-04-01

    The National Park Service has developed a long-term ecological monitoring program for 32 ecoregional networks containing more than 270 parks with significant natural resources. The monitoring program assists park managers in developing a broad-based understanding of the status and trends of park resources as a basis for making decisions and working with other agencies and the public for the long-term protection of park ecosystems. We found that the basic steps involved in planning and designing a long-term ecological monitoring program were the same for a range of ecological systems including coral reefs, deserts, arctic tundra, prairie grasslands, caves, and tropical rainforests. These steps involve (1) clearly defining goals and objectives, (2) compiling and summarizing existing information, (3) developing conceptual models, (4) prioritizing and selecting indicators, (5) developing an overall sampling design, (6) developing monitoring protocols, and (7) establishing data management, analysis, and reporting procedures. The broad-based, scientifically sound information obtained through this systems-based monitoring program will have multiple applications for management decision-making, research, education, and promoting public understanding of park resources. When combined with an effective education program, monitoring results can contribute not only to park issues, but also to larger quality-of-life issues that affect surrounding communities and can contribute significantly to the environmental health of the nation.

  14. National Pork Producers Council Maternal Line National Genetic Evaluation Program: a comparison of sow longevity and trait associations with sow longevity.

    PubMed

    Serenius, T; Stalder, K J; Baas, T J; Mabry, J W; Goodwin, R N; Johnson, R K; Robison, O W; Tokach, M; Miller, R K

    2006-09-01

    Data from the National Pork Producers Council Maternal Line National Genetic Evaluation Program were used to compare longevity of sows from 6 commercial genetic lines and to estimate the phenotypic associations of sow longevity with gilt backfat thickness, ADG, age at first farrowing, litter size at first farrowing, litter weight at first farrowing, average feed intake during lactation, and average backfat loss during lactation. The lines evaluated were American Diamond Genetics, Danbred North America, Dekalb-Monsanto DK44, Dekalb-Monsanto GPK347, Newsham Hybrids, and National Swine Registry. The data set contained information from 3,251 gilts, of which 17% had censored longevity records (sows lived longer than 6 parities). The line comparison was carried out by analyzing all lines simultaneously. Because the survival distribution functions differed among genetic lines, later analyses were carried out separately for each genetic line. All analyses were based on the non-parametric proportional hazard (Cox model). Dekalb-Monsanto GPK347 sows had a lower risk of being culled than sows from the other lines. Moreover, the shape of the survival distribution function of the Delkab-Monsanto GPK347 line was different from the other 5 lines. The Dekalb-Monsanto 347 line had lower culling rates because they had lower gilt reproductive failure before the first parity than gilts from the other lines. Within line, sows with lower feed intake and greater backfat loss during lactation had a shorter productive lifetime. Thus, producers should implement management practices having positive effects on sow lactation feed intake. Additionally, the swine genetics industry is challenged to simultaneously improve efficiency of gain of their terminal market pigs and to obtain high feed intake during lactation of their maternal lines for future improvement of sow longevity. Recording sow feed intake and backfat loss during lactation in nucleus and multiplication breeding herds should be

  15. Collection and production of indigenous plant material for national park restoration

    Treesearch

    Mark Majerus

    1999-01-01

    The National Park Service is taking the "Restoration" approach to reestablishing native plant communities by salvaging topsoil and by seeding and planting native indigenous plant materials. In this way, they are making every effort to protect the genetic integrity of the often unique native plant resource. Since 1985, Yellowstone and Glacier National Parks...

  16. An Integrated Korean Biodiversity and Genetic Information Retrieval System

    PubMed Central

    Lim, Jeongheui; Bhak, Jong; Oh, Hee-Mock; Kim, Chang-Bae; Park, Yong-Ha; Paek, Woon Kee

    2008-01-01

    Background On-line biodiversity information databases are growing quickly and being integrated into general bioinformatics systems due to the advances of fast gene sequencing technologies and the Internet. These can reduce the cost and effort of performing biodiversity surveys and genetic searches, which allows scientists to spend more time researching and less time collecting and maintaining data. This will cause an increased rate of knowledge build-up and improve conservations. The biodiversity databases in Korea have been scattered among several institutes and local natural history museums with incompatible data types. Therefore, a comprehensive database and a nation wide web portal for biodiversity information is necessary in order to integrate diverse information resources, including molecular and genomic databases. Results The Korean Natural History Research Information System (NARIS) was built and serviced as the central biodiversity information system to collect and integrate the biodiversity data of various institutes and natural history museums in Korea. This database aims to be an integrated resource that contains additional biological information, such as genome sequences and molecular level diversity. Currently, twelve institutes and museums in Korea are integrated by the DiGIR (Distributed Generic Information Retrieval) protocol, with Darwin Core2.0 format as its metadata standard for data exchange. Data quality control and statistical analysis functions have been implemented. In particular, integrating molecular and genetic information from the National Center for Biotechnology Information (NCBI) databases with NARIS was recently accomplished. NARIS can also be extended to accommodate other institutes abroad, and the whole system can be exported to establish local biodiversity management servers. Conclusion A Korean data portal, NARIS, has been developed to efficiently manage and utilize biodiversity data, which includes genetic resources. NARIS aims

  17. Assessing genetic diversity of wild Southeastern American Vaccinium species using microsatellite markers

    USDA-ARS?s Scientific Manuscript database

    The United States Department of Agriculture (USDA)-Agricultural Research Service (ARS), National Clonal Germplasm Repository (NCGR) in Corvallis, Oregon, preserves genetic resources of fruit crops. This genebank contains more than 1700 Vaccinium accessions from 33 countries. Wild species representat...

  18. Increasing global participation in genetics research through DNA barcoding.

    PubMed

    Adamowicz, Sarah J; Steinke, Dirk

    2015-12-01

    DNA barcoding--the sequencing of short, standardized DNA regions for specimen identification and species discovery--has promised to facilitate rapid access to biodiversity knowledge by diverse users. Here, we advance our opinion that increased global participation in genetics research is beneficial, both to scientists and for science, and explore the premise that DNA barcoding can help to democratize participation in genetics research. We examine publication patterns (2003-2014) in the DNA barcoding literature and compare trends with those in the broader, related domain of genomics. While genomics is the older and much larger field, the number of nations contributing to the published literature is similar between disciplines. Meanwhile, DNA barcoding exhibits a higher pace of growth in the number of publications as well as greater evenness among nations in their proportional contribution to total authorships. This exploration revealed DNA barcoding to be a highly international discipline, with growing participation by researchers in especially biodiverse nations. We briefly consider several of the challenges that may hinder further participation in genetics research, including access to training and molecular facilities as well as policy relating to the movement of genetic resources.

  19. Management advisory memorandum on resource requirement planning for operating and maintaining the National Airspace System

    DOT National Transportation Integrated Search

    1997-01-13

    Management Advisory Memorandum on Resource Requirement Planning for Operating and Maintaining the National Airspace System (NAS) in the Federal Aviation Administration (FAA). Evaluates FAA's resource requirement planning system to ensure it accuratel...

  20. Genetic conservation and paddlefish propagation

    USGS Publications Warehouse

    Sloss, Brian L.; Klumb, Robert A.; Heist, Edward J.

    2009-01-01

    The conservation of genetic diversity of our natural resources is overwhelmingly one of the central foci of 21st century management practices. Three recommendations related to the conservation of paddlefish Polyodon spathula genetic diversity are to (1) identify genetic diversity at both nuclear and mitochondrial DNA loci using a suggested list of 20 sampling locations, (2) use genetic diversity estimates to develop genetic management units, and (3) identify broodstock sources to minimize effects of supplemental stocking on the genetic integrity of native paddlefish populations. We review previous genetic work on paddlefish and described key principles and concepts associated with maintaining genetic diversity within and among paddlefish populations and also present a genetic case study of current paddlefish propagation at the U.S. Fish and Wildlife Service Gavins Point National Fish Hatchery. This study confirmed that three potential sources of broodfish were genetically indistinguishable at the loci examined, allowing the management agencies cooperating on this program flexibility in sampling gametes. This study also showed significant bias in the hatchery occurred in terms of male reproductive contribution, which resulted in a shift in the genetic diversity of progeny compared to the broodfish. This shift was shown to result from differential male contributions, partially attributed to the mode of egg fertilization. Genetic insights enable implementation of a paddlefish propagation program within an adaptive management strategy that conserves inherent genetic diversity while achieving demographic goals.

  1. [Location information acquisition and sharing application design in national census of Chinese medicine resources].

    PubMed

    Zhang, Xiao-Bo; Li, Meng; Wang, Hui; Guo, Lan-Ping; Huang, Lu-Qi

    2017-11-01

    In literature, there are many information on the distribution of Chinese herbal medicine. Limited by the technical methods, the origin of Chinese herbal medicine or distribution of information in ancient literature were described roughly. It is one of the main objectives of the national census of Chinese medicine resources, which is the background information of the types and distribution of Chinese medicine resources in the region. According to the national Chinese medicine resource census technical specifications and pilot work experience, census team with "3S" technology, computer network technology, digital camera technology and other modern technology methods, can effectively collect the location information of traditional Chinese medicine resources. Detailed and specific location information, such as regional differences in resource endowment and similarity, biological characteristics and spatial distribution, the Chinese medicine resource census data access to the accuracy and objectivity evaluation work, provide technical support and data support. With the support of spatial information technology, based on location information, statistical summary and sharing of multi-source census data can be realized. The integration of traditional Chinese medicine resources and related basic data can be a spatial integration, aggregation and management of massive data, which can help for the scientific rules data mining of traditional Chinese medicine resources from the overall level and fully reveal its scientific connotation. Copyright© by the Chinese Pharmaceutical Association.

  2. National Aquatic Resource Surveys: Integration of Geospatial Data in Their Survey Design and Analysis

    EPA Science Inventory

    The National Aquatic Resource Surveys (NARS) are a series of four statistical surveys conducted by the U.S. Environmental Protection Agency working in collaboration with states, tribal nations and other federal agencies. The surveys are conducted for lakes and reservoirs, streams...

  3. 76 FR 13976 - Eastern Idaho Resource Advisory Committee; Caribou-Targhee National Forest, Idaho Falls, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ...-Targhee National Forest, Idaho Falls, ID AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY... National Forests' Eastern Idaho Resource Advisory Committee will meet Friday, March 25, 2011 in Idaho Falls...-Targhee National Forest Headquarters Office, 1405 Hollipark Drive, Idaho Falls, Idaho 83401. FOR FURTHER...

  4. 76 FR 13345 - Eastern Idaho Resource Advisory Committee; Caribou-Targhee National Forest, Idaho Falls, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-11

    ...-Targhee National Forest, Idaho Falls, ID AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY... National Forests' Eastern Idaho Resource Advisory Committee will meet Friday, March 25, 2011 in Idaho Falls...-Targhee National Forest Headquarters Office, 1405 Hollipark Drive, Idaho Falls, Idaho 83401. FOR FURTHER...

  5. The Role of Education within National Human Resource Development Policy

    ERIC Educational Resources Information Center

    Schmidt, Kathleen V.

    2008-01-01

    Trade and economic viability are becoming increasingly important in all countries around the world. As a result, Human Resource Development (HRD) is becoming an integral part of a country's ability to sustain development and it is evident that many countries outside of the United States are integrating HRD as part of their national policy (NHRD).…

  6. Database resources of the National Center for Biotechnology Information.

    PubMed

    Wheeler, David L; Barrett, Tanya; Benson, Dennis A; Bryant, Stephen H; Canese, Kathi; Chetvernin, Vyacheslav; Church, Deanna M; DiCuccio, Michael; Edgar, Ron; Federhen, Scott; Geer, Lewis Y; Kapustin, Yuri; Khovayko, Oleg; Landsman, David; Lipman, David J; Madden, Thomas L; Maglott, Donna R; Ostell, James; Miller, Vadim; Pruitt, Kim D; Schuler, Gregory D; Sequeira, Edwin; Sherry, Steven T; Sirotkin, Karl; Souvorov, Alexandre; Starchenko, Grigory; Tatusov, Roman L; Tatusova, Tatiana A; Wagner, Lukas; Yaschenko, Eugene

    2007-01-01

    In addition to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through NCBI's Web site. NCBI resources include Entrez, the Entrez Programming Utilities, My NCBI, PubMed, PubMed Central, Entrez Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link(BLink), Electronic PCR, OrfFinder, Spidey, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, Cancer Chromosomes, Entrez Genome, Genome Project and related tools, the Trace and Assembly Archives, the Map Viewer, Model Maker, Evidence Viewer, Clusters of Orthologous Groups (COGs), Viral Genotyping Tools, Influenza Viral Resources, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus (GEO), Entrez Probe, GENSAT, Online Mendelian Inheritance in Man (OMIM), Online Mendelian Inheritance in Animals (OMIA), the Molecular Modeling Database (MMDB), the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART) and the PubChem suite of small molecule databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. These resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov.

  7. Genetic Resources of Watermelon

    USDA-ARS?s Scientific Manuscript database

    As a result of many years of domestication and selection for desirable fruit quality, watermelon cultivars (Citrullus lanatus) share a narrow genetic base. Africa is the center of origin and diversity of watermelon and is considered to be the central continent for collecting and conserving useful ge...

  8. Database resources of the National Center for Biotechnology Information

    PubMed Central

    Wheeler, David L.; Barrett, Tanya; Benson, Dennis A.; Bryant, Stephen H.; Canese, Kathi; Chetvernin, Vyacheslav; Church, Deanna M.; DiCuccio, Michael; Edgar, Ron; Federhen, Scott; Geer, Lewis Y.; Helmberg, Wolfgang; Kapustin, Yuri; Kenton, David L.; Khovayko, Oleg; Lipman, David J.; Madden, Thomas L.; Maglott, Donna R.; Ostell, James; Pruitt, Kim D.; Schuler, Gregory D.; Schriml, Lynn M.; Sequeira, Edwin; Sherry, Stephen T.; Sirotkin, Karl; Souvorov, Alexandre; Starchenko, Grigory; Suzek, Tugba O.; Tatusov, Roman; Tatusova, Tatiana A.; Wagner, Lukas; Yaschenko, Eugene

    2006-01-01

    In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through NCBI's Web site. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central, Entrez Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Electronic PCR, OrfFinder, Spidey, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, Cancer Chromosomes, Entrez Genomes and related tools, the Map Viewer, Model Maker, Evidence Viewer, Clusters of Orthologous Groups, Retroviral Genotyping Tools, HIV-1, Human Protein Interaction Database, SAGEmap, Gene Expression Omnibus, Entrez Probe, GENSAT, Online Mendelian Inheritance in Man, Online Mendelian Inheritance in Animals, the Molecular Modeling Database, the Conserved Domain Database, the Conserved Domain Architecture Retrieval Tool and the PubChem suite of small molecule databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized datasets. All of the resources can be accessed through the NCBI home page at: . PMID:16381840

  9. 15 CFR 291.4 - National industry-specific pollution prevention and environmental compliance resource centers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false National industry-specific pollution... § 291.4 National industry-specific pollution prevention and environmental compliance resource centers... information on pollution prevention opportunities, regulatory compliance and technologies and techniques for...

  10. Genetic improvement of shortleaf pine on the Mark Twain, Ouachita, and Ozark National Forests

    Treesearch

    Charly Studyvin; David Gwaze

    2007-01-01

    A genetic conservation and breeding program for shortleaf pine (Pinus echinata Mill.) was initiated in the 1960s by the Mark Twain National Forest in Missouri. Superior trees were selected from natural stands throughout the Forest. Fifty of the top-ranked superior trees were grafted into a first generation seed orchard at the Ouachita National Forest...

  11. Access and benefits sharing of genetic resources and associated traditional knowledge in northern Canada: understanding the legal environment and creating effective research agreements

    PubMed Central

    Geary, Janis; Jardine, Cynthia G.; Guebert, Jenilee; Bubela, Tania

    2013-01-01

    Background Research in northern Canada focused on Aboriginal peoples has historically benefited academia with little consideration for the people being researched or their traditional knowledge (TK). Although this attitude is changing, the complexity of TK makes it difficult to develop mechanisms to preserve and protect it. Protecting TK becomes even more important when outside groups become interested in using TK or materials with associated TK. In the latter category are genetic resources, which may have commercial value and are the focus of this article. Objective This article addresses access to and use of genetic resources and associated TK in the context of the historical power-imbalances in research relationships in Canadian north. Design Review. Results Research involving genetic resources and TK is becoming increasingly relevant in northern Canada. The legal framework related to genetic resources and the cultural shift of universities towards commercial goals in research influence the environment for negotiating research agreements. Current guidelines for research agreements do not offer appropriate guidelines to achieve mutual benefit, reflect unequal bargaining power or take the relationship between parties into account. Conclusions Relational contract theory may be a useful framework to address the social, cultural and legal hurdles inherent in creating research agreements. PMID:23986896

  12. Genetic status and conservation of Westslope Cutthroat Trout in Glacier National Park

    USGS Publications Warehouse

    Muhlfeld, Clint C.; D'Angelo, Vincent S.; Downs, Christopher C.; Powell, John D.; Amish, Stephen J.; Luikart, Gordon; Kovach, Ryan; Boyer, Matthew; Kalinowski, Steven T.

    2016-01-01

    Invasive hybridization is one of the greatest threats to the persistence of Westslope Cutthroat Trout Oncorhynchus clarkii lewisi. Large protected areas, where nonhybridized populations are interconnected and express historical life history and genetic diversity, provide some of the last ecological and evolutionary strongholds for conserving this species. Here, we describe the genetic status and distribution of Westslope Cutthroat Trout throughout Glacier National Park, Montana. Admixture between Westslope Cutthroat Trout and introduced Rainbow Trout O. mykiss and Yellowstone Cutthroat Trout O. clarkii bouvieri was estimated by genotyping 1,622 fish collected at 115 sites distributed throughout the Columbia, Missouri, and South Saskatchewan River drainages. Currently, Westslope Cutthroat Trout occupy an estimated 1,465 km of stream habitat and 45 lakes (9,218 ha) in Glacier National Park. There was no evidence of introgression in samples from 32 sites along 587 km of stream length (40% of the stream kilometers currently occupied) and 17 lakes (2,555 ha; 46% of the lake area currently occupied). However, nearly all (97%) of the streams and lakes that were occupied by nonhybridized populations occurred in the Columbia River basin. Based on genetic status (nonnative genetic admixture ≤ 10%), 36 Westslope Cutthroat Trout populations occupying 821 km of stream and 5,482 ha of lakes were identified as “conservation populations.” Most of the conservation populations (N = 27; 736 km of stream habitat) occurred in the Columbia River basin, whereas only a few geographically restricted populations were found in the South Saskatchewan River (N = 7; 55 km) and Missouri River (N = 2; 30 km) basins. Westslope Cutthroat Trout appear to be at imminent risk of genomic extinction in the South Saskatchewan and Missouri River basins, whereas populations in the Columbia River basin are widely distributed and conservation efforts are actively addressing threats from

  13. National Resources [and] National Toll Free Numbers.

    ERIC Educational Resources Information Center

    National Information Center for Children and Youth with Disabilities, Washington, DC.

    This resource list provides names, addresses, and telephone numbers of 13 information clearinghouses and 42 organizations providing information on children and youth with disabilities. Telephone numbers are designated as either voice or text telephone. Spanish-language resources are also indicated. A list of organizations that have national…

  14. U.S. 2013 National Climate Assessment of Oceans and Marine Resources

    NASA Astrophysics Data System (ADS)

    Doney, S. C.; Rosenberg, A.

    2012-12-01

    We will discuss the key findings from the Oceans and Marine Resources chapter of the U.S. 2013 National Climate Assessment. As a nation, we depend on the ocean for seafood, recreation and tourism, cultural heritage, transportation of goods, and increasingly, energy and other critical resources. The U.S. ocean Exclusive Economic Zone extends 200 nautical miles seaward from the coast, spanning an area about 1.7 times the land area of the continental United States and encompassing waters along the U.S. east, west and Gulf coasts, around Alaska and Hawaii, and including the U.S. territories in the Pacific and Caribbean. This vast region is host to a rich diversity of marine plants and animals and a wide range of ecosystems from tropical coral reefs to sea-ice covered, polar waters in the Arctic. We will highlight the current state of knowledge on changing ocean climate conditions, such as warming, sea-ice retreat and ocean acidification, and how these may be impacting valuable marine ecosystems and the array of resources and services we derive from the sea now and into the future. We will also touch on the interaction of climate change impacts with other human factors including pollution and over-fishing.

  15. 77 FR 34997 - Notice of June 30, 2012, Meeting for Denali National Park Subsistence Resource Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-12

    ... DEPARTMENT OF THE INTERIOR National Park Service [NPS-AKRO-DENA-10403; 9924-PYS] Notice of June 30, 2012, Meeting for Denali National Park Subsistence Resource Commission AGENCY: National Park Service...) 644-3603. If you are interested in applying for Denali National Park SRC membership, contact the...

  16. Molecular testing for cystic fibrosis carrier status practice guidelines: recommendations of the National Society of Genetic Counselors.

    PubMed

    Langfelder-Schwind, Elinor; Karczeski, Barbara; Strecker, Michelle N; Redman, Joy; Sugarman, Elaine A; Zaleski, Christina; Brown, Trisha; Keiles, Steven; Powers, Amy; Ghate, Sumheda; Darrah, Rebecca

    2014-02-01

    To provide practice recommendations for genetic counselors whose clients are considering cystic fibrosis (CF) carrier testing or seeking information regarding CF molecular test results. The goals of these recommendations are to: 1) Provide updated information about the natural history, diagnosis, and treatment of CF and related conditions. 2) Supplement genetic counselors' knowledge and understanding of the available carrier screening and diagnostic testing options. 3) Describe the current state of genotype/phenotype correlations for CFTR mutations and an approach to interpreting both novel and previously described variants. 4) Provide a framework for genetic counselors to assist clients' decision-making regarding CF carrier testing, prenatal diagnosis, and pregnancy management. Disclaimer The practice guidelines of the National Society of Genetic Counselors (NSGC) are developed by members of the NSGC to assist genetic counselors and other health care providers in making decisions about appropriate management of genetic concerns; including access to and/or delivery of services. Each practice guideline focuses on a clinical or practice-based issue, and is the result of a review and analysis of current professional literature believed to be reliable. As such, information and recommendations within the NSGC practice guidelines reflect the current scientific and clinical knowledge at the time of publication, are only current as of their publication date, and are subject to change without notice as advances emerge.In addition, variations in practice, which take into account the needs of the individual patient and the resources and limitations unique to the institution or type of practice, may warrant approaches, treatments and/or procedures that differ from the recommendations outlined in this guideline. Therefore, these recommendations should not be construed as dictating an exclusive course of management, nor does the use of such recommendations guarantee a particular

  17. Systematic review of the empirical investigation of resources to support decision-making regarding BRCA1 and BRCA2 genetic testing in women with breast cancer.

    PubMed

    Grimmett, Chloe; Pickett, Karen; Shepherd, Jonathan; Welch, Karen; Recio-Saucedo, Alejandra; Streit, Elke; Seers, Helen; Armstrong, Anne; Cutress, Ramsey I; Evans, D Gareth; Copson, Ellen; Meiser, Bettina; Eccles, Diana; Foster, Claire

    2018-05-01

    Identify existing resources developed and/or evaluated empirically in the published literature designed to support women with breast cancer making decisions regarding genetic testing for BRCA1/2 mutations. Systematic review of seven electronic databases. Studies were included if they described or evaluated resources that were designed to support women with breast cancer in making a decision to have genetic counselling or testing for familial breast cancer. Outcome and process evaluations, using any type of study design, as well as articles reporting the development of decision aids, were eligible for inclusion. Total of 9 publications, describing 6 resources were identified. Resources were effective at increasing knowledge or understanding of hereditary breast cancer. Satisfaction with resources was high. There was no evidence that any resource increased distress, worry or decisional conflict. Few resources included active functionalities for example, values-based exercises, to support decision-making. Tailored resources supporting decision-making may be helpful and valued by patients and increase knowledge of hereditary breast cancer, without causing additional distress. Clinicians should provide supportive written information to patients where it is available. However, there is a need for robustly developed decision tools to support decision-making around genetic testing in women with breast cancer. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Soil and Oil, Trees and Seas: Building Nations through Natural Resources

    ERIC Educational Resources Information Center

    Hu, Helen

    2014-01-01

    This article describes the activities of the tribal colleges and universities in building programs aimed at helping students and energy companies acquire the skills needed for employment in the natural resource industries around the Native nations. Students are learning many skills--welding, construction technology, and safety. Students are also…

  19. Natural Resource Management Plan for Brookhaven National Laboratory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    green, T.

    This comprehensive Natural Resource Management Plan (NRMP) for Brookhaven National Laboratory (BNL) was built on the successful foundation of the Wildlife Management Plan for BNL, which it replaces. This update to the 2003 plan continues to build on successes and efforts to better understand the ecosystems and natural resources found on the BNL site. The plan establishes the basis for managing the varied natural resources located on the 5,265 acre BNL site, setting goals and actions to achieve those goals. The planning of this document is based on the knowledge and expertise gained over the past 10 years by themore » Natural Resources management staff at BNL in concert with local natural resource agencies including the New York State Department of Environmental Conservation, Long Island Pine Barrens Joint Planning and Policy Commission, The Nature Conservancy, and others. The development of this plan is an attempt at sound ecological management that not only benefits BNL's ecosystems but also benefits the greater Pine Barrens habitats in which BNL is situated. This plan applies equally to the Upton Ecological and Research Reserve (Upton Reserve). Any difference in management between the larger BNL area and the Upton Reserve are noted in the text. The purpose of the Natural Resource Management Plan (NRMP) is to provide management guidance, promote stewardship of the natural resources found at BNL, and to sustainably integrate their protection with pursuit of the Laboratory's mission. The philosophy or guiding principles of the NRMP are stewardship, sustainability, adaptive ecosystem management, compliance, integration with other plans and requirements, and the incorporation of community involvement, where applicable. The NRMP is periodically reviewed and updated, typically every five years. This review and update was delayed to develop documents associated with a new third party facility, the Long Island Solar Farm. This two hundred acre facility will result in

  20. Strategic Resource Dependence, Conflict, and Implications for U.S. National Security Policy in the Twenty-First Century

    DTIC Science & Technology

    2012-12-14

    technology that comprises the Internet. Among them are aluminum, antimony, barium, cadmium , chromium, copper, gold, iron, lead , mercury, platinum...dependence. This may lead to resource conflict as nations continue their pursuit of prosperity and security. National leaders will inevitably change or adopt... mineral resources associated with computerization and advanced electronics will markedly increase in their strategic relative importance. This

  1. Assembled genomic and tissue-specific transcriptomic data resources for two genetically distinct lines of Cowpea ( Vigna unguiculata (L.) Walp)

    PubMed Central

    Spriggs, Andrew; Henderson, Steven T.; Hand, Melanie L.; Johnson, Susan D.; Taylor, Jennifer M.; Koltunow, Anna

    2018-01-01

    Cowpea ( Vigna unguiculata (L.) Walp) is an important legume crop for food security in areas of low-input and smallholder farming throughout Africa and Asia. Genetic improvements are required to increase yield and resilience to biotic and abiotic stress and to enhance cowpea crop performance. An integrated cowpea genomic and gene expression data resource has the potential to greatly accelerate breeding and the delivery of novel genetic traits for cowpea. Extensive genomic resources for cowpea have been absent from the public domain; however, a recent early release reference genome for IT97K-499-35 ( Vigna unguiculata v1.0, NSF, UCR, USAID, DOE-JGI, http://phytozome.jgi.doe.gov/) has now been established in a collaboration between the Joint Genome Institute (JGI) and University California (UC) Riverside. Here we release supporting genomic and transcriptomic data for IT97K-499-35 and a second transformable cowpea variety, IT86D-1010. The transcriptome resource includes six tissue-specific datasets for each variety, with particular emphasis on reproductive tissues that extend and support the V. unguiculata v1.0 reference. Annotations have been included in our resource to allow direct mapping to the v1.0 cowpea reference. Access to this resource provided here is supported by raw and assembled data downloads. PMID:29528046

  2. Assembled genomic and tissue-specific transcriptomic data resources for two genetically distinct lines of Cowpea ( Vigna unguiculata (L.) Walp).

    PubMed

    Spriggs, Andrew; Henderson, Steven T; Hand, Melanie L; Johnson, Susan D; Taylor, Jennifer M; Koltunow, Anna

    2018-02-09

    Cowpea ( Vigna unguiculata (L.) Walp) is an important legume crop for food security in areas of low-input and smallholder farming throughout Africa and Asia. Genetic improvements are required to increase yield and resilience to biotic and abiotic stress and to enhance cowpea crop performance. An integrated cowpea genomic and gene expression data resource has the potential to greatly accelerate breeding and the delivery of novel genetic traits for cowpea. Extensive genomic resources for cowpea have been absent from the public domain; however, a recent early release reference genome for IT97K-499-35 ( Vigna unguiculata  v1.0, NSF, UCR, USAID, DOE-JGI, http://phytozome.jgi.doe.gov/) has now been established in a collaboration between the Joint Genome Institute (JGI) and University California (UC) Riverside. Here we release supporting genomic and transcriptomic data for IT97K-499-35 and a second transformable cowpea variety, IT86D-1010. The transcriptome resource includes six tissue-specific datasets for each variety, with particular emphasis on reproductive tissues that extend and support the V. unguiculata v1.0 reference. Annotations have been included in our resource to allow direct mapping to the v1.0 cowpea reference. Access to this resource provided here is supported by raw and assembled data downloads.

  3. Perceptions of agriculture and natural resource careers among minority students in a national organization

    Treesearch

    Corliss Wilson Outley

    2008-01-01

    The purpose of the study was to identify factors that influence the career choice behaviors among students who were members of Minorities in Agriculture, Natural Resources and Related Sciences (MANRRS) National Society. A secondary purpose was to identify perceptions and attitudes among students that chose careers in agriculture and natural resources. The MANRRS...

  4. 77 FR 58868 - Teleconference for the National Park Service Alaska Region's Subsistence Resource Commission Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ... Park Subsistence Resource Commission (SRC) and the Wrangell-St. Elias National Park SRC will meet to... and Location for Next Meeting 12. Adjourn Meeting Wrangell-St. Elias National Park SRC Meeting Date and Location: The [[Page 58869

  5. Resources for National Water Savings for Outdoor Water Use

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Melody, Moya; Stratton, Hannah; Williams, Alison

    2014-05-01

    In support of efforts by the U.S. Environmental Agency's (EPA's) WaterSense program to develop a spreadsheet model for calculating the national water and financial savings attributable to WaterSense certification and labeling of weather-based irrigation controllers, Lawrence Berkeley National Laboratory reviewed reports, technical data, and other information related to outdoor water use and irrigation controllers. In this document we categorize and describe the reviewed references, highlighting pertinent data. We relied on these references when developing model parameters and calculating controller savings. We grouped resources into three major categories: landscapes (section 1); irrigation devices (section 2); and analytical and modeling efforts (sectionmore » 3). Each category is subdivided further as described in its section. References are listed in order of date of publication, most recent first.« less

  6. PROBABILISTIC MONITORING FOR TRIBAL AQUATIC RESOURCE: EPA'S NATIONAL COASTAL ASSESSMENT TRIBAL TRAINING

    EPA Science Inventory

    Harvey, James, David Lawes, Vincent Cooke and Tom Heitmuller. In press. Probabilistic Monitoring for Tribal Aquatic Resources: EPA's National Coastal Assessment Tribal Training (Abstract). To be presented at the Monitoring Science and Technology Symposium, 20-24 September 2004, D...

  7. Conservation of the USDA-ARS National Plant Germplasm System Apple Collection using dormant bud cryopreservation

    USDA-ARS?s Scientific Manuscript database

    The USDA-ARS National Plant Germplasm System maintains a grafted collection of apple accessions representing 49 taxa in Geneva, NY. Since 1993, dormant buds of many of these accessions have been routinely cryopreserved at the USDA-ARS National Center for Genetic Resources Preservation (NCGRP) in For...

  8. Lupus - resources

    MedlinePlus

    Resources - lupus ... The following organizations are good resources for information on systemic lupus erythematosus : Genetics Home Reference -- ghr.nlm.nih.gov/condition/systemic-lupus-erythematosus Lupus Foundation of America -- ...

  9. Genetic differentiation and trade among populations of peach palm ( Bactris gasipaes Kunth) in the Peruvian Amazon-implications for genetic resource management.

    PubMed

    Adin, A; Weber, J C; Sotelo Montes, C; Vidaurre, H; Vosman, B; Smulders, M J M

    2004-05-01

    Peach palm ( Bactris gasipaes Kunth) is cultivated for fruit and 'heart of palm', and is an important component of agroforestry systems in the Peruvian Amazon. In this study, AFLP was used to compare genetic diversity among domesticated populations along the Paranapura and Cuiparillo rivers, which are managed by indigenous and colonist farming communities, respectively. Gene diversity was 0.2629 for the populations in indigenous communities and 0.2534 in colonist communities. Genetic differentiation among populations ( G(st)) was 0.0377-0.0416 ( P<0.01) among populations along both rivers. There was no relation between genetic differentiation and the geographical location of populations along the rivers. Since natural seed dispersal by birds and rodents is thought to occur only across relatively short distances (100-200 m), it is likely that exchange of material by farmers and commercial traders is responsible for most of the 'long-distance' (over more than 20 km) gene flow among populations along the two rivers studied. This exchange of material may be important to counteract the effects of selection as well as genetic drift in small groups of trees in farmers' fields, much as in a metapopulation, and may account for the weak genetic differentiation between the two rivers ( G(st)=0.0249, P<0.01). A comparison with samples from other landraces in Peru and Brazil showed the existence of an isolation-by-distance structure up to 3,000 km, consistent with gene flow on a regional scale, likely mediated by trade in the Amazon Basin. Results are discussed with regard to practical implications for the management of genetic resources with farming communities.

  10. Database resources of the National Center for Biotechnology Information

    PubMed Central

    Sayers, Eric W.; Barrett, Tanya; Benson, Dennis A.; Bolton, Evan; Bryant, Stephen H.; Canese, Kathi; Chetvernin, Vyacheslav; Church, Deanna M.; DiCuccio, Michael; Federhen, Scott; Feolo, Michael; Fingerman, Ian M.; Geer, Lewis Y.; Helmberg, Wolfgang; Kapustin, Yuri; Krasnov, Sergey; Landsman, David; Lipman, David J.; Lu, Zhiyong; Madden, Thomas L.; Madej, Tom; Maglott, Donna R.; Marchler-Bauer, Aron; Miller, Vadim; Karsch-Mizrachi, Ilene; Ostell, James; Panchenko, Anna; Phan, Lon; Pruitt, Kim D.; Schuler, Gregory D.; Sequeira, Edwin; Sherry, Stephen T.; Shumway, Martin; Sirotkin, Karl; Slotta, Douglas; Souvorov, Alexandre; Starchenko, Grigory; Tatusova, Tatiana A.; Wagner, Lukas; Wang, Yanli; Wilbur, W. John; Yaschenko, Eugene; Ye, Jian

    2012-01-01

    In addition to maintaining the GenBank® nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the NCBI Website. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central (PMC), Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Primer-BLAST, COBALT, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, dbVar, Epigenomics, Genome and related tools, the Map Viewer, Model Maker, Evidence Viewer, Trace Archive, Sequence Read Archive, BioProject, BioSample, Retroviral Genotyping Tools, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus (GEO), Probe, Online Mendelian Inheritance in Animals (OMIA), the Molecular Modeling Database (MMDB), the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART), Biosystems, Protein Clusters and the PubChem suite of small molecule databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov. PMID:22140104

  11. Database resources of the National Center for Biotechnology Information.

    PubMed

    Sayers, Eric W; Barrett, Tanya; Benson, Dennis A; Bolton, Evan; Bryant, Stephen H; Canese, Kathi; Chetvernin, Vyacheslav; Church, Deanna M; Dicuccio, Michael; Federhen, Scott; Feolo, Michael; Fingerman, Ian M; Geer, Lewis Y; Helmberg, Wolfgang; Kapustin, Yuri; Krasnov, Sergey; Landsman, David; Lipman, David J; Lu, Zhiyong; Madden, Thomas L; Madej, Tom; Maglott, Donna R; Marchler-Bauer, Aron; Miller, Vadim; Karsch-Mizrachi, Ilene; Ostell, James; Panchenko, Anna; Phan, Lon; Pruitt, Kim D; Schuler, Gregory D; Sequeira, Edwin; Sherry, Stephen T; Shumway, Martin; Sirotkin, Karl; Slotta, Douglas; Souvorov, Alexandre; Starchenko, Grigory; Tatusova, Tatiana A; Wagner, Lukas; Wang, Yanli; Wilbur, W John; Yaschenko, Eugene; Ye, Jian

    2012-01-01

    In addition to maintaining the GenBank® nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the NCBI Website. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central (PMC), Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Primer-BLAST, COBALT, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, dbVar, Epigenomics, Genome and related tools, the Map Viewer, Model Maker, Evidence Viewer, Trace Archive, Sequence Read Archive, BioProject, BioSample, Retroviral Genotyping Tools, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus (GEO), Probe, Online Mendelian Inheritance in Animals (OMIA), the Molecular Modeling Database (MMDB), the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART), Biosystems, Protein Clusters and the PubChem suite of small molecule databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov.

  12. Database resources of the National Center for Biotechnology Information.

    PubMed

    Sayers, Eric W; Barrett, Tanya; Benson, Dennis A; Bryant, Stephen H; Canese, Kathi; Chetvernin, Vyacheslav; Church, Deanna M; DiCuccio, Michael; Edgar, Ron; Federhen, Scott; Feolo, Michael; Geer, Lewis Y; Helmberg, Wolfgang; Kapustin, Yuri; Landsman, David; Lipman, David J; Madden, Thomas L; Maglott, Donna R; Miller, Vadim; Mizrachi, Ilene; Ostell, James; Pruitt, Kim D; Schuler, Gregory D; Sequeira, Edwin; Sherry, Stephen T; Shumway, Martin; Sirotkin, Karl; Souvorov, Alexandre; Starchenko, Grigory; Tatusova, Tatiana A; Wagner, Lukas; Yaschenko, Eugene; Ye, Jian

    2009-01-01

    In addition to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the NCBI web site. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central, Entrez Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Electronic PCR, OrfFinder, Spidey, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, Cancer Chromosomes, Entrez Genomes and related tools, the Map Viewer, Model Maker, Evidence Viewer, Clusters of Orthologous Groups (COGs), Retroviral Genotyping Tools, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus (GEO), Entrez Probe, GENSAT, Online Mendelian Inheritance in Man (OMIM), Online Mendelian Inheritance in Animals (OMIA), the Molecular Modeling Database (MMDB), the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART) and the PubChem suite of small molecule databases. Augmenting many of the web applications is custom implementation of the BLAST program optimized to search specialized data sets. All of the resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov.

  13. An Ounce of Prevention Beats a Pound of Cure: Resourcing the State Department to Defend the Nation

    DTIC Science & Technology

    2010-04-01

    17 The DOS lacks the resources to lead USG efforts .....................................................25 Summary...failing states 5) The DOS lacks the resources to lead USG efforts After compelling the reader to accept these five arguments, a disparity in US foreign...world‟s most powerful nation. The nation-states in which these terrorists operate lack the ability to monitor or disrupt the operations of these

  14. The Factors and Conditions for National Human Resource Development in Brazil

    ERIC Educational Resources Information Center

    Sparkman, Torrence E.

    2015-01-01

    Purpose: The purpose of this paper is to understand the factors and conditions that influence national human resource development (NHRD) in Brazil. In this paper, the transitioning nature of the political, economic, social and educational conditions; the current challenges and trends that may impact NHRD; and the current status of NHRD research in…

  15. The current state of the creation and modernization of national geodetic and cartographic resources in Poland

    NASA Astrophysics Data System (ADS)

    Doskocz, Adam

    2016-01-01

    All official data are currently integrated and harmonized in a spatial reference system. This paper outlines a national geodetic and cartographic resources in Poland. The national geodetic and cartographic resources are an important part of the spatial information infrastructure in the European Community. They also provide reference data for other resources of Spatial Data Infrastructure (SDI), including: main and detailed geodetic control networks, base maps, land and buildings registries, geodetic registries of utilities and topographic maps. This paper presents methods of producing digital map data and technical standards for field surveys, and in addition paper also presents some aspects of building Global and Regional SDI.

  16. Singapore National Medical Image Resource Centre (SN.MIRC): a world wide web resource for radiology education.

    PubMed

    Yang, Guo-Liang; Lim, C C Tchoyoson

    2006-08-01

    Radiology education is heavily dependent on visual images, and case-based teaching files comprising medical images can be an important tool for teaching diagnostic radiology. Currently, hardcopy film is being rapidly replaced by digital radiological images in teaching hospitals, and an electronic teaching file (ETF) library would be desirable. Furthermore, a repository of ETFs deployed on the World Wide Web has the potential for e-learning applications to benefit a larger community of learners. In this paper, we describe a Singapore National Medical Image Resource Centre (SN.MIRC) that can serve as a World Wide Web resource for teaching diagnostic radiology. On SN.MIRC, ETFs can be created using a variety of mechanisms including file upload and online form-filling, and users can search for cases using the Medical Image Resource Center (MIRC) query schema developed by the Radiological Society of North America (RSNA). The system can be improved with future enhancements, including multimedia interactive teaching files and distance learning for continuing professional development. However, significant challenges exist when exploring the potential of using the World Wide Web for radiology education.

  17. Assessing Genetic Literacy Awareness and Knowledge Gaps in the US Population: Results from the Health Information National Trends Survey.

    PubMed

    Krakow, Melinda; Ratcliff, Chelsea L; Hesse, Bradford W; Greenberg-Worisek, Alexandra J

    2018-05-31

    Public understanding of the role of genetics in disease risk is key to appropriate disease prevention and detection. This study assessed the current extent of awareness and use of genetic testing in the US population. Additionally, the study identified characteristics of subgroups more likely to be at risk for low genetic literacy. The study used data from the National Cancer Institute's 2017 Health Information National Trends Survey, including measures of genetic testing awareness, genetic testing applications and genetic testing usage. Multivariable logistic regression models estimated associations between sociodemographics, genetic testing awareness, and genetic testing use. Fifty-seven percent of respondents were aware of genetic tests. Testing awareness differed by age, household income, and race/ethnicity. Most participants had heard of using tests to determine personal disease risk (82.58%) or inherited disease risk in children (81.41%), but less were familiar with determining treatment (38.29%) or drug efficacy (40.76%). Among those with genetic testing awareness, actual testing uptake was low. A large portion of the general public lacks genetic testing awareness and may benefit from educational campaigns. As precision medicine expands, increasing public awareness about genetic testing applications for disease prevention and treatment will be important to support population health. This is a work of the US Government and is not subject to copyright protection in the United States. Foreign copyrights may apply. Published by S. Karger AG, Basel.

  18. 75 FR 18470 - Olympic National Forest; Federal Register-Title II Resource Advisory Committee Meeting Advisory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ... DEPARTMENT OF AGRICULTURE Forest Service Olympic National Forest; Federal Register--Title II Resource Advisory Committee Meeting Advisory AGENCY: Olympic National Forest, USDA Forest Service. ACTION... recommendations for Title II projects to be funded by the Secure Rural Schools and Community Self- Determination...

  19. Uranium resource assessment by the Geological Survey; methodology and plan to update the national resource base

    USGS Publications Warehouse

    Finch, Warren Irvin; McCammon, Richard B.

    1987-01-01

    Based on the Memorandum of Understanding {MOU) of September 20, 1984, between the U.S. Geological Survey of the U.S. Department of Interior and the Energy Information Administration {EIA) of the U.S. Department of Energy {DOE), the U.S. Geological Survey began to make estimates of the undiscovered uranium endowment of selected areas of the United States in 1985. A modified NURE {National Uranium Resource Evaluation) method will be used in place of the standard NURE method of the DOE that was used for the national assessment reported in October 1980. The modified method, here named the 'deposit-size-frequency' {DSF) method, is presented for the first time, and calculations by the two methods are compared using an illustrative example based on preliminary estimates for the first area to be evaluated under the MOU. The results demonstrate that the estimate of the endowment using the DSF method is significantly larger and more uncertain than the estimate obtained by the NURE method. We believe that the DSF method produces a more realistic estimate because the principal factor estimated in the endowment equation is disaggregated into more parts and is more closely tied to specific geologic knowledge than by the NURE method. The DSF method consists of modifying the standard NURE estimation equation, U=AxFxTxG, by replacing the factors FxT by a single factor that represents the tonnage for the total number of deposits in all size classes. Use of the DSF method requires that the size frequency of deposits in a known or control area has been established and that the relation of the size-frequency distribution of deposits to probable controlling geologic factors has been determined. Using these relations, the principal scientist {PS) first estimates the number and range of size classes and then, for each size class, estimates the lower limit, most likely value, and upper limit of the numbers of deposits in the favorable area. Once these probable estimates have been refined

  20. High-fidelity national carbon mapping for resource management and REDD+

    PubMed Central

    2013-01-01

    Background High fidelity carbon mapping has the potential to greatly advance national resource management and to encourage international action toward climate change mitigation. However, carbon inventories based on field plots alone cannot capture the heterogeneity of carbon stocks, and thus remote sensing-assisted approaches are critically important to carbon mapping at regional to global scales. We advanced a high-resolution, national-scale carbon mapping approach applied to the Republic of Panama – one of the first UN REDD + partner countries. Results Integrating measurements of vegetation structure collected by airborne Light Detection and Ranging (LiDAR) with field inventory plots, we report LiDAR-estimated aboveground carbon stock errors of ~10% on any 1-ha land parcel across a wide range of ecological conditions. Critically, this shows that LiDAR provides a highly reliable replacement for inventory plots in areas lacking field data, both in humid tropical forests and among drier tropical vegetation types. We then scale up a systematically aligned LiDAR sampling of Panama using satellite data on topography, rainfall, and vegetation cover to model carbon stocks at 1-ha resolution with estimated average pixel-level uncertainty of 20.5 Mg C ha-1 nationwide. Conclusions The national carbon map revealed strong abiotic and human controls over Panamanian carbon stocks, and the new level of detail with estimated uncertainties for every individual hectare in the country sets Panama at the forefront in high-resolution ecosystem management. With this repeatable approach, carbon resource decision-making can be made on a geospatially explicit basis, enhancing human welfare and environmental protection. PMID:23866822

  1. Metagenomics for mining new genetic resources of microbial communities.

    PubMed

    Ferrer, Manuel; Beloqui, Ana; Timmis, Kenneth N; Golyshin, Peter N

    2009-01-01

    Recent progress has revealed that the capture of genetic resources of complex microbial communities in metagenome libraries allows the discovery of a richness of new enzymatic diversity that had not previously been imagined. Activity-based screening of such libraries has demonstrated that this new diversity is not simply variations on known sequence themes, but rather the existence of entirely new sequence classes and novel functionalities. This new diversity, the surface of which has thus far only been scratched, constitutes potential for a wealth of new and improved applications in industry, medicine, agriculture, etc., and promises to facilitate in a significant manner our transition to a sustainable society, by contributing to the transition to renewable sources of energy, chemicals and materials, the lowering of pollutant burdens, lower processes energies, etc. Current bottlenecks in metagenomics include insufficient functional characterization and amplifying non-validated annotations of proteins in databases. Copyright (c) 2008 S. Karger AG, Basel.

  2. Genetic resources offer efficient tools for rice functional genomics research.

    PubMed

    Lo, Shuen-Fang; Fan, Ming-Jen; Hsing, Yue-Ie; Chen, Liang-Jwu; Chen, Shu; Wen, Ien-Chie; Liu, Yi-Lun; Chen, Ku-Ting; Jiang, Mirng-Jier; Lin, Ming-Kuang; Rao, Meng-Yen; Yu, Lin-Chih; Ho, Tuan-Hua David; Yu, Su-May

    2016-05-01

    Rice is an important crop and major model plant for monocot functional genomics studies. With the establishment of various genetic resources for rice genomics, the next challenge is to systematically assign functions to predicted genes in the rice genome. Compared with the robustness of genome sequencing and bioinformatics techniques, progress in understanding the function of rice genes has lagged, hampering the utilization of rice genes for cereal crop improvement. The use of transfer DNA (T-DNA) insertional mutagenesis offers the advantage of uniform distribution throughout the rice genome, but preferentially in gene-rich regions, resulting in direct gene knockout or activation of genes within 20-30 kb up- and downstream of the T-DNA insertion site and high gene tagging efficiency. Here, we summarize the recent progress in functional genomics using the T-DNA-tagged rice mutant population. We also discuss important features of T-DNA activation- and knockout-tagging and promoter-trapping of the rice genome in relation to mutant and candidate gene characterizations and how to more efficiently utilize rice mutant populations and datasets for high-throughput functional genomics and phenomics studies by forward and reverse genetics approaches. These studies may facilitate the translation of rice functional genomics research to improvements of rice and other cereal crops. © 2015 John Wiley & Sons Ltd.

  3. Genetic variability in krill.

    PubMed

    Valentine, J W; Ayala, F J

    1976-02-01

    We have estimated genetic variability by gel electrophoresis in three species of krill, genus Euphausia (Arthropoda: Crustacea). Genetic variability is low where trophic resources are most seasonal, and high where trophic resources are most stable. Simlar trends have been found in benthic marine invertebrates. The observed trends of genetic variability do not correlate with trends in the stability of physical environment parameters.

  4. Database resources of the National Center for Biotechnology Information: 2002 update

    PubMed Central

    Wheeler, David L.; Church, Deanna M.; Lash, Alex E.; Leipe, Detlef D.; Madden, Thomas L.; Pontius, Joan U.; Schuler, Gregory D.; Schriml, Lynn M.; Tatusova, Tatiana A.; Wagner, Lukas; Rapp, Barbara A.

    2002-01-01

    In addition to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides data analysis and retrieval resources that operate on the data in GenBank and a variety of other biological data made available through NCBI’s web site. NCBI data retrieval resources include Entrez, PubMed, LocusLink and the Taxonomy Browser. Data analysis resources include BLAST, Electronic PCR, OrfFinder, RefSeq, UniGene, HomoloGene, Database of Single Nucleotide Polymorphisms (dbSNP), Human Genome Sequencing, Human MapViewer, Human¡VMouse Homology Map, Cancer Chromosome Aberration Project (CCAP), Entrez Genomes, Clusters of Orthologous Groups (COGs) database, Retroviral Genotyping Tools, SAGEmap, Gene Expression Omnibus (GEO), Online Mendelian Inheritance in Man (OMIM), the Molecular Modeling Database (MMDB) and the Conserved Domain Database (CDD). Augmenting many of the web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of the resources can be accessed through the NCBI home page at http://www.ncbi.nlm.nih.gov. PMID:11752242

  5. Recommended minimal emergency equipment and resources for schools: national consensus group report.

    PubMed

    Bobo, Nichole; Hallenbeck, Paula; Robinson, Judith

    2003-06-01

    Providing an environment that is responsive to emergency health needs of students is essential to creating a safe setting for children in schools. The question of what minimal essential emergency equipment and resources should be available in schools brings with it many and varied opinions, issues, and concerns. Through funding from the Emergency Medical Services for Children (EMSC), the National Association of School Nurses (NASN) was charged with the task of convening a consensus group to formulate a recommended list of minimal essential emergency equipment and resources that should be present in all schools. This article provides an overview of the issues surrounding minimal emergency equipment needs for schools, presents recommended minimal emergency equipment and resources, and recommendations for further actions.

  6. National assessment of geologic carbon dioxide storage resources: summary

    USGS Publications Warehouse

    ,

    2013-01-01

    The U.S. Geological Survey (USGS) recently completed an evaluation of the technically accessible storage resource (TASR) for carbon dioxide (CO2) for 36 sedimentary basins in the onshore areas and State waters of the United States. The TASR is an estimate of the geologic storage resource that may be available for CO2 injection and storage and is based on current geologic and hydrologic knowledge of the subsurface and current engineering practices. By using a geology-based probabilistic assessment methodology, the USGS assessment team members obtained a mean estimate of approximately 3,000 metric gigatons (Gt) of subsurface CO2 storage capacity that is technically accessible below onshore areas and State waters; this amount is more than 500 times the 2011 annual U.S. energy-related CO2 emissions of 5.5 Gt (U.S. Energy Information Administration, 2012, http://www.eia.gov/environment/emissions/carbon/). In 2007, the Energy Independence and Security Act (Public Law 110–140) directed the U.S. Geological Survey to conduct a national assessment of geologic storage resources for CO2 in consultation with the U.S. Environmental Protection Agency, the U.S. Department of Energy, and State geological surveys. The USGS developed a methodology to estimate storage resource potential in geologic formations in the United States (Burruss and others, 2009, USGS Open-File Report (OFR) 2009–1035; Brennan and others, 2010, USGS OFR 2010–1127; Blondes, Brennan, and others, 2013, USGS OFR 2013–1055). In 2012, the USGS completed the assessment, and the results are summarized in this Fact Sheet and are provided in more detail in companion reports (U.S. Geological Survey Geologic Carbon Dioxide Storage Resources Assessment Team, 2013a,b; see related reports at right). The goal of this project was to conduct an initial assessment of storage capacity on a regional basis, and results are not intended for use in the evaluation of specific sites for potential CO2 storage. The national

  7. [Book review] Fish Gene Pools: preservation of genetic resources in relation to wild fish stocks, edited by N. Ryman

    USGS Publications Warehouse

    Simon, R.C.

    1984-01-01

    Review of: Fish Gene Pools: Preservation of Genetic Resources in Relation to Wild Fish Stocks. Edited by N. Ryman. The Editorial Service/FRN, Box 6710, S-11385, Stockholm, Sweden. 1981. 111 pages. $16.00 (paper).

  8. Water-resources investigations in Dinosaur National Monument, Utah-Colorado, fiscal year 1970

    USGS Publications Warehouse

    Sumsion, C.T.

    1971-01-01

    Water-resources data were acquired during fiscal year 1970 by the U.S. Geological Survey at Dinosaur National Monument, Utah-Colorado, for the U.S. National Park Service as part of a continuing project. The data provide a basis for planning the development, management, and use of the available water resources to provide adequate water supplies. Thirty-one springs, 19 in relatively inaccessible areas, were evaluated as sources of water supplies. Seven potential well sites were evaluated for drilling depths in specific aquifers. A well drilled in Echo Park near the confluence of the Green and Yampa Rivers was tested. The pumping test showed the well to yield 130 gallons per minute with a drawdown of 1.96 feet; specific capacity of the well at 130 gallons per minute is 66 gallons per minute per foot. Water samples for chemical analysis were - collected from nine springs and one well; all except that from Disappointment Spring, were of good chemical quality.

  9. New drug information resources for pharmacists at the National Library of Medicine.

    PubMed

    Knoben, James E; Phillips, Steven J

    2014-01-01

    To provide an overview of selected drug information-related databases of the National Library of Medicine (NLM), with a focus on newer resources that support the professional information needs of pharmacists and other health care providers. NLM, which is the world's largest medical library, provides an array of bibliographic, factual, and evidence-based drug, herbal remedy, and dietary supplement information resources. Five of the more recently introduced online resources include areas of particular importance to pharmacists, including a repository of current product labeling/package inserts, with automated search links to associated information resources; a portal to drug information that allows pharmacists to search multiple databases simultaneously and link to related medication and health care information resources; authoritative information on the effects of medications, herbal remedies, and dietary supplements in nursing infants and their mothers; comprehensive information, including a case registry, on the potential for liver toxicity due to drugs, herbal remedies, and dietary supplements; and a pill identification system with two intuitive search methodologies. NLM provides several clinical-scientific drug information resources that are particularly useful in meeting the professional information needs of pharmacists.

  10. Economics and the 1995 National Assessment of U.S. oil and gas resources

    USGS Publications Warehouse

    Attanasi, E.D.

    1995-01-01

    This report summarizes the economic component of the U.S. Geological Survey's 1995 National Assessment of oil and gas resources for the US onshore areas and State waters. This area accounts for 80 percent of US hydrocarbon production and 85 percent of US proved reserves. The Minerals Management Service has released a parallel study for Federal offshore areas (1996). Estimates are as of January 1994. The economic evaluation uses mean values of the technically recoverable resources assessed by geologists.

  11. Database resources of the National Center for Biotechnology Information.

    PubMed

    Sayers, Eric W; Barrett, Tanya; Benson, Dennis A; Bolton, Evan; Bryant, Stephen H; Canese, Kathi; Chetvernin, Vyacheslav; Church, Deanna M; DiCuccio, Michael; Federhen, Scott; Feolo, Michael; Fingerman, Ian M; Geer, Lewis Y; Helmberg, Wolfgang; Kapustin, Yuri; Landsman, David; Lipman, David J; Lu, Zhiyong; Madden, Thomas L; Madej, Tom; Maglott, Donna R; Marchler-Bauer, Aron; Miller, Vadim; Mizrachi, Ilene; Ostell, James; Panchenko, Anna; Phan, Lon; Pruitt, Kim D; Schuler, Gregory D; Sequeira, Edwin; Sherry, Stephen T; Shumway, Martin; Sirotkin, Karl; Slotta, Douglas; Souvorov, Alexandre; Starchenko, Grigory; Tatusova, Tatiana A; Wagner, Lukas; Wang, Yanli; Wilbur, W John; Yaschenko, Eugene; Ye, Jian

    2011-01-01

    In addition to maintaining the GenBank® nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the NCBI Web site. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central (PMC), Entrez Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Primer-BLAST, COBALT, Electronic PCR, OrfFinder, Splign, ProSplign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, dbVar, Epigenomics, Cancer Chromosomes, Entrez Genomes and related tools, the Map Viewer, Model Maker, Evidence Viewer, Trace Archive, Sequence Read Archive, Retroviral Genotyping Tools, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus (GEO), Entrez Probe, GENSAT, Online Mendelian Inheritance in Man (OMIM), Online Mendelian Inheritance in Animals (OMIA), the Molecular Modeling Database (MMDB), the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART), IBIS, Biosystems, Peptidome, OMSSA, Protein Clusters and the PubChem suite of small molecule databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov.

  12. An overview of the Valles Caldera National Preserve: the natural and cultural resources

    USGS Publications Warehouse

    Parmenter, Robert R.; Steffen, Anastasia; Allen, Craig D.; Kues, Barry S.; Kelley, Shari A.; Lueth, Virgil W.

    2007-01-01

    The Valles Caldera National Preserve is one of New Mexico’s natural wonders and a popular area for public recreation, sustainable natural resource production, and scientific research and education. Here, we provide a concise overview of the natural and cultural history of the Preserve, including descriptions of the ecosystems, flora and fauna. We note that, at the landscape scale, the Valles caldera appears to be spectacularly pristine; however, humans have extracted resources from the Preserve area for many centuries, resulting in localized impacts to forests, grasslands and watersheds. The Valles Caldera Trust is now charged with managing the Preserve and providing public access, while preserving and restoring these valuable public resources.

  13. National Aquatic Resource Surveys (NARS) N/P Values for Streams - Wadeable Streams Assessment

    EPA Pesticide Factsheets

    The National Aquatic Resource Survey (NARS) findings for nutrients in streams and lakes highlight that nutrient pollution is widespread across the United States and impacts biological communities. The NARS analysis examined the range of values for nutrients in least-disturbed sites in a WSA region [WSA regions are modified Level III ecoregions from Omernik (1987)] and used this distribution for nitrogen (N) and phosphorus (P) to separate sites into those having high, medium, or low concentrations of nutrients. Sites identified as high were worse (i.e., had higher nutrient concentrations) than 95% of the sites used to define least-disturbed condition. Similarly, the 75th percentile of the least-disturbed distribution was used to distinguish between sites in medium and low condition. This means that sites reported as being as low were as good as or better than 75% of the sites used to define least-disturbed condition. A relative risk analysis of the data from this survey found that nationally streams and lakes have more than two times greater risk of having degraded biological communities when nutrient concentrations are high than when they are low. For more information, please consult the National Wadeable Streams Assessment (WSA) Report available online at: https://www.epa.gov/national-aquatic-resource-surveys/nrsa:

  14. Conservation of indigenous cattle genetic resources in Southern Africa's smallholder areas: turning threats into opportunities - A review.

    PubMed

    Nyamushamba, G B; Mapiye, C; Tada, O; Halimani, T E; Muchenje, V

    2017-05-01

    The current review focuses on characterization and conservation efforts vital for the development of breeding programmes for indigenous beef cattle genetic resources in Southern Africa. Indigenous African cattle breeds were identified and characterized using information from refereed journals, conference papers and research reports. Results of this current review reviewed that smallholder beef cattle production in Southern Africa is extensive and dominated by indigenous beef cattle strains adaptable to the local environment. The breeds include Nguni, Mashona, Tuli, Malawi Zebu, Bovino de Tete, Angoni, Landim, Barotse, Twsana and Ankole. These breeds have important functions ranging from provision of food and income to socio-economic, cultural and ecological roles. They also have adaptive traits ranging from drought tolerant, resistance to ticks and tick borne diseases, heat tolerance and resistance to trypanosomosis. Stakeholders in the conservation of beef cattle were also identified and they included farmers, national government, research institutes and universities as well as breeding companies and societies in Southern Africa. Research efforts made to evaluate threats and opportunities of indigenous beef cattle production systems, assess the contribution of indigenous cattle to household food security and income, genetically and phenotypically characterize and conserve indigenous breeds, and develop breeding programs for smallholder beef production are highlighted. Although smallholder beef cattle production in the smallholder farming systems contributes substantially to household food security and income, their productivity is hindered by several constraints that include high prevalence of diseases and parasites, limited feed availability and poor marketing. The majority of the African cattle populations remain largely uncharacterized although most of the indigenous cattle breeds have been identified.

  15. Genetic variability in krill.

    PubMed Central

    Valentine, J W; Ayala, F J

    1976-01-01

    We have estimated genetic variability by gel electrophoresis in three species of krill, genus Euphausia (Arthropoda: Crustacea). Genetic variability is low where trophic resources are most seasonal, and high where trophic resources are most stable. Simlar trends have been found in benthic marine invertebrates. The observed trends of genetic variability do not correlate with trends in the stability of physical environment parameters. Images PMID:1061166

  16. Identification and Analysis of National Airspace System Resource Constraints

    NASA Technical Reports Server (NTRS)

    Smith, Jeremy C.; Marien, Ty V.; Viken, Jeffery K.; Neitzke, Kurt W.; Kwa, Tech-Seng; Dollyhigh, Samuel M.; Fenbert, James W.; Hinze, Nicolas K.

    2015-01-01

    This analysis is the deliverable for the Airspace Systems Program, Systems Analysis Integration and Evaluation Project Milestone for the Systems and Portfolio Analysis (SPA) focus area SPA.4.06 Identification and Analysis of National Airspace System (NAS) Resource Constraints and Mitigation Strategies. "Identify choke points in the current and future NAS. Choke points refer to any areas in the en route, terminal, oceanic, airport, and surface operations that constrain actual demand in current and projected future operations. Use the Common Scenarios based on Transportation Systems Analysis Model (TSAM) projections of future demand developed under SPA.4.04 Tools, Methods and Scenarios Development. Analyze causes, including operational and physical constraints." The NASA analysis is complementary to a NASA Research Announcement (NRA) "Development of Tools and Analysis to Evaluate Choke Points in the National Airspace System" Contract # NNA3AB95C awarded to Logistics Management Institute, Sept 2013.

  17. Genetic variation and seed zones of Douglas-fir in the Siskiyou National Forest.

    Treesearch

    Robert K. Campbell; Albert I. Sugano

    1993-01-01

    Provisional seed zones and breeding zones were developed for Douglas-fir (Pseudotsuga menziesii (Mirb.) Franco) in the Siskiyou National Forest in southwestern Oregon. Zones were based on maps of genetic variation patterns obtained by evaluating genotypes of trees from 260 locations in the region. Genotypes controlling growth vigor and growth...

  18. The national coal-resources data system of the U.S. geological survey

    USGS Publications Warehouse

    Carter, M.D.

    1976-01-01

    The National Coal Resources Data System (NCRDS) was designed by the U.S. Geological Survey (USGS) to meet the increasing demands for rapid retrieval of information on coal location, quantity, quality, and accessibility. An interactive conversational query system devised by the USGS retrieves information from the data bank through a standard computer terminal. The system is being developed in two phases. Phase I, which currently is available on a limited basis, contains published areal resource and chemical data. The primary objective of this phase is to retrieve, calculate, and tabulate coal-resource data by area on a local, regional, or national scale. Factors available for retrieval include: state, county, quadrangle, township, coal field, coal bed, formation, geologic age, source and reliability of data, and coal-bed rank, thickness, overburden, and tonnage, or any combinations of variables. In addition, the chemical data items include individual values for proximate and ultimate analyses, BTU value, and several other physical and chemical tests. Information will be validated and deleted or updated as needed. Phase II is being developed to store, retrieve, and manipulate basic point source coal data (e.g., field observations, drill-hole logs), including geodetic location; bed thickness; depth of burial; moisture; ash; sulfur; major-, minor-, and trace-element content; heat value; and characteristics of overburden, roof rocks, and floor rocks. The computer system may be used to generate interactively structure-contour or isoline maps of the physical and chemical characteristics of a coal bed or to calculate coal resources. ?? 1976.

  19. Geologic Resource Evaluation of Kaloko-Honokohau National Historical Park, Hawai'i: Geology and Coastal Landforms

    USGS Publications Warehouse

    Richmond, Bruce M.; Gibbs, Ann E.; Cochran, Susan A.

    2008-01-01

    Geologic resource inventories of lands managed by the National Park Service (NPS) are important products for the parks and are designed to provide scientific information to better manage park resources. Park-specific geologic reports are used to identify geologic features and processes that are relevant to park ecosystems, evaluate the impact of human activities on geologic features and processes, identify geologic research and monitoring needs, and enhance opportunities for education and interpretation. These geologic reports are planned to provide a brief geologic history of the park and address specific geologic issues that link the park geology and the resource manager. The Kona coast National Parks of the Island of Hawai'i are intended to preserve the natural beauty of the Kona coast and protect significant ancient structures and artifacts of the native Hawaiians. Pu'ukohola Heiau National Historic Site (PUHE), Kaloko-Honokohau National Historical Park (KAHO), and Pu'uhonua O Honaunau National Historical Park (PUHO) are three Kona parks studied by the U.S. Geological Survey (USGS) Coastal and Marine Geology Team in cooperation with the National Park Service. This report is one of six related reports designed to provide geologic and benthic-habitat information for the three Kona parks. Each geology and coastal-landform report describes the regional geologic setting of the Hawaiian Islands, gives a general description of the geology of the Kona coast, and presents the geologic setting and issues for one of the parks. The related benthic-habitat mapping reports discuss the marine data and habitat classification scheme, and present results of the mapping program. Kaloko-Honokohau National Historical Park (KAHO) was established in 1978 in order to preserve and protect traditional native Hawaiian culture and cultural sites. The park is the site of an ancient Hawaiian settlement, occupies 469 ha and is considered a locale of considerable cultural and historical

  20. Economics and the 1995 National Assessment of United States Oil and Gas Resources

    USGS Publications Warehouse

    Attanasi, E.D.

    1998-01-01

    This report summarizes the economic component of the 1995 National Assessment of Oil and Gas Resources prepared by the U.S. Geological Survey for onshore and State offshore areas of the United States. Province and regional incremental cost functions for conventional undiscovered oil and gas fields, and selected unconventional oil and gas accumulations, allowing the ranking of areas by the incremental costs finding, developing, and producing these resources. Regional projections of additions to reserves from previously discovered fields to 2015 are also presented.

  1. Genetic connectivity for two bear species at wildlife crossing structures in Banff National Park.

    PubMed

    Sawaya, Michael A; Kalinowski, Steven T; Clevenger, Anthony P

    2014-04-07

    Roads can fragment and isolate wildlife populations, which will eventually decrease genetic diversity within populations. Wildlife crossing structures may counteract these impacts, but most crossings are relatively new, and there is little evidence that they facilitate gene flow. We conducted a three-year research project in Banff National Park, Alberta, to evaluate the effectiveness of wildlife crossings to provide genetic connectivity. Our main objective was to determine how the Trans-Canada Highway and crossing structures along it affect gene flow in grizzly (Ursus arctos) and black bears (Ursus americanus). We compared genetic data generated from wildlife crossings with data collected from greater bear populations. We detected a genetic discontinuity at the highway in grizzly bears but not in black bears. We assigned grizzly bears that used crossings to populations north and south of the highway, providing evidence of bidirectional gene flow and genetic admixture. Parentage tests showed that 47% of black bears and 27% of grizzly bears that used crossings successfully bred, including multiple males and females of both species. Differentiating between dispersal and gene flow is difficult, but we documented gene flow by showing migration, reproduction and genetic admixture. We conclude that wildlife crossings allow sufficient gene flow to prevent genetic isolation.

  2. Genetic connectivity for two bear species at wildlife crossing structures in Banff National Park

    PubMed Central

    Sawaya, Michael A.; Kalinowski, Steven T.; Clevenger, Anthony P.

    2014-01-01

    Roads can fragment and isolate wildlife populations, which will eventually decrease genetic diversity within populations. Wildlife crossing structures may counteract these impacts, but most crossings are relatively new, and there is little evidence that they facilitate gene flow. We conducted a three-year research project in Banff National Park, Alberta, to evaluate the effectiveness of wildlife crossings to provide genetic connectivity. Our main objective was to determine how the Trans-Canada Highway and crossing structures along it affect gene flow in grizzly (Ursus arctos) and black bears (Ursus americanus). We compared genetic data generated from wildlife crossings with data collected from greater bear populations. We detected a genetic discontinuity at the highway in grizzly bears but not in black bears. We assigned grizzly bears that used crossings to populations north and south of the highway, providing evidence of bidirectional gene flow and genetic admixture. Parentage tests showed that 47% of black bears and 27% of grizzly bears that used crossings successfully bred, including multiple males and females of both species. Differentiating between dispersal and gene flow is difficult, but we documented gene flow by showing migration, reproduction and genetic admixture. We conclude that wildlife crossings allow sufficient gene flow to prevent genetic isolation. PMID:24552834

  3. An Online Resource of Digital Stories About Cancer Genetics: Qualitative Study of Patient Preferences and Information Needs

    PubMed Central

    Mundy, Lisa; Hilgart, Jennifer

    2011-01-01

    Background The Cancer Genetics Service for Wales (CGSW) was established in 1998 as an all-Wales service for individuals with concerns about their family history of cancer. CGSW offers a range of services such as risk assessment, genetic counseling, and genetic testing. Individuals referred to cancer genetics services often have unmet information and support needs, and they value access to practical and experiential information from other patients and health professionals. As a result of the lifelong nature of genetic conditions, a fundamental challenge is to meet the ongoing needs of these patients by providing easily accessible and reliable information. Objectives Our aims were to explore how the long-term information and support needs of CGSW patients could be met and to assess whether an online bank of digital stories about cancer genetics would be acceptable to patients. Methods In 2009, CGSW organized patient panels across Wales. During these events, 169 patients were asked for their feedback about a potential online resource of digital stories from CGSW patients and staff. A total of 75 patients registered to take part in the project and 23 people from across Wales agreed to share their story. All participants took part in a follow-up interview. Results Patient preferences for an online collection of cancer genetics stories were collected at the patient panels. Key topics to be covered by the stories were identified, and this feedback informed the development of the website to ensure that patients’ needs would be met. The 23 patient storytellers were aged between 28 and 75 years, and 19 were female. The digital stories reflect patients’ experiences within CGSW and the implications of living with or at risk of cancer. Follow-up interviews with patient storytellers showed that they shared their experiences as a means of helping other patients and to increase understanding of the cancer genetics service. Digital stories were also collected from 12 members of

  4. Population genetics of the California National Primate Research Center’s (CNPRC) captive Callicebuscupreus colony

    PubMed Central

    Mendoza, Adrian; Ng, Jillian; Bales, Karen; Mendoza, Sally P.; George, Debra A.; Smith, David Glenn; Kanthaswamy, Sree

    2014-01-01

    The California National Primate Research Center (CNPRC) maintains a small colony of titi monkeys (Callicebuscupreus) for behavioral studies. While short tandem repeat (STR) markers are critical for the genetic management of the center’s rhesus macaque (Macacamulatta) breeding colony, STRs are not used for this purpose in the maintenance of the center’s titi monkey colony. Consequently, the genetic structure of this titi monkey population has not been characterized. A lack of highly informative genetic markers in titi monkeys has also resulted in scant knowledge of the species’ genetic variation in the wild. The purpose of this study was to develop a panel of highly polymorphic titi monkey STRs using a cross-species PCR amplification protocol that could be used for the genetic management of the titi monkey colony. We screened 16 STR primer pairs and selected those that generated robust and reproducible polymorphic amplicons. Loci that were found to be highly polymorphic, very likely to be useful for parentage verification, pedigree assessment, and for studying titi monkey population genetics, were validated using Hardy-Weinberg equilibrium and linkage disequilibrium analyses. The genetic data generated in this study were also used to directly assess the impact of a recent adenovirus outbreak on the colony’s genetic diversity. While the adenovirus epizootic disease caused significant mortality (19 deaths among the 65 colony animals), our results suggest that the disease exhibited little or no influence on the overall genetic diversity of the colony. PMID:25179309

  5. Allele Mining in Barley Genetic Resources Reveals Genes of Race-Non-Specific Powdery Mildew Resistance

    PubMed Central

    Spies, Annika; Korzun, Viktor; Bayles, Rosemary; Rajaraman, Jeyaraman; Himmelbach, Axel; Hedley, Pete E.; Schweizer, Patrick

    2012-01-01

    Race-non-specific, or quantitative, pathogen resistance is of high importance to plant breeders due to its expected durability. However, it is usually controlled by multiple quantitative trait loci (QTL) and therefore difficult to handle in practice. Knowing the genes that underlie race-non-specific resistance (NR) would allow its exploitation in a more targeted manner. Here, we performed an association-genetic study in a customized worldwide collection of spring barley accessions for candidate genes of race-NR to the powdery mildew fungus Blumeria graminis f. sp. hordei (Bgh) and combined data with results from QTL mapping as well as functional-genomics approaches. This led to the identification of 11 associated genes with converging evidence for an important role in race-NR in the presence of the Mlo gene for basal susceptibility. Outstanding in this respect was the gene encoding the transcription factor WRKY2. The results suggest that unlocking plant genetic resources and integrating functional-genomic with genetic approaches can accelerate the discovery of genes underlying race-NR in barley and other crop plants. PMID:22629270

  6. Genetic Counseling

    MedlinePlus

    ... Testing Evaluating Genomic Tests Epidemiology Pathogen Genomics Resources Genetic Counseling Recommend on Facebook Tweet Share Compartir In ... informed decisions about testing and treatment. Reasons for Genetic Counseling There are many reasons that people go ...

  7. How do you know things are getting better (or not?) Assessing resource conditions in National Parks and Protected Areas

    Treesearch

    James D. Nations

    2011-01-01

    The National Parks Conservation Association’s Center for State of the Parks uses an easily explained, fact-based methodology to determine the condition of natural and cultural resources in the United States National Park System. Researchers assess and numerically score natural resources that include water quality and quantity, climate change impacts, forest...

  8. Lawrence Livermore National Laboratories Perspective on Code Development and High Performance Computing Resources in Support of the National HED/ICF Effort

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Clouse, C. J.; Edwards, M. J.; McCoy, M. G.

    2015-07-07

    Through its Advanced Scientific Computing (ASC) and Inertial Confinement Fusion (ICF) code development efforts, Lawrence Livermore National Laboratory (LLNL) provides a world leading numerical simulation capability for the National HED/ICF program in support of the Stockpile Stewardship Program (SSP). In addition the ASC effort provides high performance computing platform capabilities upon which these codes are run. LLNL remains committed to, and will work with, the national HED/ICF program community to help insure numerical simulation needs are met and to make those capabilities available, consistent with programmatic priorities and available resources.

  9. Coronado National Forest Draft Land and Resource Management Plan: Cochise, Graham, Pima, Pinal, and Santa Cruz Counties, Arizona, and Hidalgo County, New Mexico

    Treesearch

    Terry Austin; Yolynda Begay; Sharon Biedenbender; Rachael Biggs; Erin Boyle; Eli Curiel; Sarah Davis; Sara Dechter; Tami Emmett; Mary Farrell; Richard Gerhart; William Gillespie; Polly Haessig; Ed Holloway; Melissa Jenkins; Larry Jones; Debby Kriegel; Robert Lefevre; Mark Stamer; Mindi Lehew; Ann Lynch; George McKay; Linda Peery; Albert Peralta; Jennifer Ruyle; Jeremy Sautter; Kenna Schoenle; Salek Shafiqullah; Christopher Stetson; Mindi Sue Vogel; Laura White; Craig Wilcox; Judy York

    2013-01-01

    The Coronado National Forest is an administrative component of the National Forest System. It administers 1,783,639 acres of National Forest System lands. National forests across the United States were established to provide natural resource-based goods and services to American citizens, and to protect timber and watershed resources. Management of national forests is...

  10. How Are Genetic Conditions Diagnosed?

    MedlinePlus

    ... Consultation How are genetic conditions diagnosed? How are genetic conditions diagnosed? A doctor may suspect a diagnosis ... and advocacy resources. For more information about diagnosing genetic conditions: Genetics Home Reference provides information about genetic ...

  11. Canadian Open Genetics Repository (COGR): a unified clinical genomics database as a community resource for standardising and sharing genetic interpretations.

    PubMed

    Lerner-Ellis, Jordan; Wang, Marina; White, Shana; Lebo, Matthew S

    2015-07-01

    The Canadian Open Genetics Repository is a collaborative effort for the collection, storage, sharing and robust analysis of variants reported by medical diagnostics laboratories across Canada. As clinical laboratories adopt modern genomics technologies, the need for this type of collaborative framework is increasingly important. A survey to assess existing protocols for variant classification and reporting was delivered to clinical genetics laboratories across Canada. Based on feedback from this survey, a variant assessment tool was made available to all laboratories. Each participating laboratory was provided with an instance of GeneInsight, a software featuring versioning and approval processes for variant assessments and interpretations and allowing for variant data to be shared between instances. Guidelines were established for sharing data among clinical laboratories and in the final outreach phase, data will be made readily available to patient advocacy groups for general use. The survey demonstrated the need for improved standardisation and data sharing across the country. A variant assessment template was made available to the community to aid with standardisation. Instances of the GeneInsight tool were provided to clinical diagnostic laboratories across Canada for the purpose of uploading, transferring, accessing and sharing variant data. As an ongoing endeavour and a permanent resource, the Canadian Open Genetics Repository aims to serve as a focal point for the collaboration of Canadian laboratories with other countries in the development of tools that take full advantage of laboratory data in diagnosing, managing and treating genetic diseases. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  12. Genetic Simulation Tools for Post-Genome Wide Association Studies of Complex Diseases

    PubMed Central

    Amos, Christopher I.; Bafna, Vineet; Hauser, Elizabeth R.; Hernandez, Ryan D.; Li, Chun; Liberles, David A.; McAllister, Kimberly; Moore, Jason H.; Paltoo, Dina N.; Papanicolaou, George J.; Peng, Bo; Ritchie, Marylyn D.; Rosenfeld, Gabriel; Witte, John S.

    2014-01-01

    Genetic simulation programs are used to model data under specified assumptions to facilitate the understanding and study of complex genetic systems. Standardized data sets generated using genetic simulation are essential for the development and application of novel analytical tools in genetic epidemiology studies. With continuing advances in high-throughput genomic technologies and generation and analysis of larger, more complex data sets, there is a need for updating current approaches in genetic simulation modeling. To provide a forum to address current and emerging challenges in this area, the National Cancer Institute (NCI) sponsored a workshop, entitled “Genetic Simulation Tools for Post-Genome Wide Association Studies of Complex Diseases” at the National Institutes of Health (NIH) in Bethesda, Maryland on March 11-12, 2014. The goals of the workshop were to: (i) identify opportunities, challenges and resource needs for the development and application of genetic simulation models; (ii) improve the integration of tools for modeling and analysis of simulated data; and (iii) foster collaborations to facilitate development and applications of genetic simulation. During the course of the meeting the group identified challenges and opportunities for the science of simulation, software and methods development, and collaboration. This paper summarizes key discussions at the meeting, and highlights important challenges and opportunities to advance the field of genetic simulation. PMID:25371374

  13. Proceedings of the National Silviculture Workshop: Silviculture for All Resources; Sacramento, CA; May 11-14, 1987

    Treesearch

    Melanie Malespin Woolever; Mike Smith; Elizabeth McGraw; Mike Lanasa; Arthur C. Zack; Chris Reichert; Robert MacWhorter; Michael R. Lennartz; Richard A. Lancia; Marc G. Rounsaville; James R. Sedell; Fred H. Everest; David R. Gibbons; Stephen R. Shifley; Melinda Moeur; David A. Marquis; Richard O. Fitzgerald; Nelson Loftus; Thomas C. Turpin; William R. Terrill; Glenn L. Crouch; Wayne D. Shepperd; Edith W. Petrick; John J. Petrick; Roger W. Dennington; Allan W. Ashton; Hubertus J. Mittmann; Gary Thompson; Ken Sonksen; David A. Stark; Michael A. Ware; Allan J. West; Patrick D. Jackson; Richard L. Bassett; Jimmie D. Chew; William B. White; Bruce W. Morse; Mike Znerold; Russell T. Graham; Peyton W. Owston; Richard G. Miller; John R. Nesbitt; Gaston Porterie; Ernest Del Rio

    1987-01-01

    The 1987 National Silviculture Workshop was held in Sacramento, California, and the Eldorado National Forest. The purpose of the workshop was to discuss, review, and share information and experiences regarding how silviculture can serve as the tool to help accomplish the objectives of many resources.

  14. Migraine - resources

    MedlinePlus

    Resources - migraine ... The following organizations are good resources for information on migraines : American Migraine Foundation -- americanmigrainefoundation.org National Headache Foundation -- headaches.org National Institute of Neurological Disorders and Stroke -- ...

  15. ERIC First Analysis: Water Resources; 1985-86 National High School Debate Resolutions.

    ERIC Educational Resources Information Center

    Wagner, David L.; Fraleigh, Douglas

    Designed to serve as a framework from which high school debate students, coaches, and judges can evaluate the issues, arguments and evidence present in the availability and quality of water resources in the United States, this booklet provides guidelines for research on the 1985-86 debate resolutions selected by the National Federation of State…

  16. Association of Genetic Loci with Sleep Apnea in European Americans and African-Americans: The Candidate Gene Association Resource (CARe)

    PubMed Central

    Patel, Sanjay R.; Goodloe, Robert; De, Gourab; Kowgier, Matthew; Weng, Jia; Buxbaum, Sarah G.; Cade, Brian; Fulop, Tibor; Gharib, Sina A.; Gottlieb, Daniel J.; Hillman, David; Larkin, Emma K.; Lauderdale, Diane S.; Li, Li; Mukherjee, Sutapa; Palmer, Lyle; Zee, Phyllis; Zhu, Xiaofeng; Redline, Susan

    2012-01-01

    Although obstructive sleep apnea (OSA) is known to have a strong familial basis, no genetic polymorphisms influencing apnea risk have been identified in cross-cohort analyses. We utilized the National Heart, Lung, and Blood Institute (NHLBI) Candidate Gene Association Resource (CARe) to identify sleep apnea susceptibility loci. Using a panel of 46,449 polymorphisms from roughly 2,100 candidate genes on a customized Illumina iSelect chip, we tested for association with the apnea hypopnea index (AHI) as well as moderate to severe OSA (AHI≥15) in 3,551 participants of the Cleveland Family Study and two cohorts participating in the Sleep Heart Health Study. Among 647 African-Americans, rs11126184 in the pleckstrin (PLEK) gene was associated with OSA while rs7030789 in the lysophosphatidic acid receptor 1 (LPAR1) gene was associated with AHI using a chip-wide significance threshold of p-value<2×10−6. Among 2,904 individuals of European ancestry, rs1409986 in the prostaglandin E2 receptor (PTGER3) gene was significantly associated with OSA. Consistency of effects between rs7030789 and rs1409986 in LPAR1 and PTGER3 and apnea phenotypes were observed in independent clinic-based cohorts. Novel genetic loci for apnea phenotypes were identified through the use of customized gene chips and meta-analyses of cohort data with replication in clinic-based samples. The identified SNPs all lie in genes associated with inflammation suggesting inflammation may play a role in OSA pathogenesis. PMID:23155414

  17. Chronic pain - resources

    MedlinePlus

    Pain - resources; Resources - chronic pain ... The following organizations are good resources for information on chronic pain: American Chronic Pain Association -- theacpa.org National Fibromyalgia and Chronic Pain Association -- www.fmcpaware.org National ...

  18. A Natural Resource Condition Assessment for Rocky Mountain National Park

    USGS Publications Warehouse

    Theobald, D.M.; Baron, Jill S.; Newman, P.; Noon, B.; Norman, J. B.; Leinwand, I.; Linn, S.E.; Sherer, R.; Williams, K.E.; Hartman, M.

    2010-01-01

    We conducted a natural resource assessment of Rocky Mountain National Park (ROMO) to provide a synthesis of existing scientific data and knowledge to address the current conditions for a subset of important park natural resources. The intent is for this report to help provide park resource managers with data and information, particularly in the form of spatially-explicit maps and GIS databases, about those natural resources and to place emerging issues within a local, regional, national, or global context. With an advisory team, we identified the following condition indicators that would be useful to assess the condition of the park: Air and Climate: Condition of alpine lakes and atmospheric deposition Water: Extent and connectivity of wetland and riparian areas Biotic Integrity: Extent of exotic terrestrial plant species, extent of fish distributions, and extent of suitable beaver habitat Landscapes: Extent and pattern of major ecological systems and natural landscapes connectivity These indicators are summarized in the following pages. We also developed two maps of important issues for use by park managers: visitor use (thru accessibility modeling) and proportion of watersheds affected by beetle kill. Based on our analysis, we believe that there is a high degree of concern for the following indicators: condition of alpine lakes; extent and connectivity of riparian/wetland areas; extent of exotic terrestrial plants (especially below 9,500’); extent of fish distributions; extent of suitable beaver habitat; and natural landscapes and connectivity. We found a low degree of concern for: the extent and pattern of major ecological systems. The indicators and issues were also summarized by the 34 watershed units (HUC12) within the park. Generally, we found six watersheds to be in “pristine” condition: Black Canyon Creek, Comanche Creek, Middle Saint Vrain Creek, South Fork of the Cache la Poudre, Buchanan Creek, and East Inlet. Four watersheds were found to have

  19. Analyzing legacy U.S. Geological Survey geochemical databases using GIS: applications for a national mineral resource assessment

    USGS Publications Warehouse

    Yager, Douglas B.; Hofstra, Albert H.; Granitto, Matthew

    2012-01-01

    This report emphasizes geographic information system analysis and the display of data stored in the legacy U.S. Geological Survey National Geochemical Database for use in mineral resource investigations. Geochemical analyses of soils, stream sediments, and rocks that are archived in the National Geochemical Database provide an extensive data source for investigating geochemical anomalies. A study area in the Egan Range of east-central Nevada was used to develop a geographic information system analysis methodology for two different geochemical datasets involving detailed (Bureau of Land Management Wilderness) and reconnaissance-scale (National Uranium Resource Evaluation) investigations. ArcGIS was used to analyze and thematically map geochemical information at point locations. Watershed-boundary datasets served as a geographic reference to relate potentially anomalous sample sites with hydrologic unit codes at varying scales. The National Hydrography Dataset was analyzed with Hydrography Event Management and ArcGIS Utility Network Analyst tools to delineate potential sediment-sample provenance along a stream network. These tools can be used to track potential upstream-sediment-contributing areas to a sample site. This methodology identifies geochemically anomalous sample sites, watersheds, and streams that could help focus mineral resource investigations in the field.

  20. Analytical Study of E-Learning Resources in National Open University of Nigeria

    ERIC Educational Resources Information Center

    Ajegbomogun, Fredrick Olatunji; Okunlaya, Rifqah Olufunmilayo Afolake; Alawiye, Mariam Kehinde

    2017-01-01

    This paper analyses e-learning resources in the National Open University of Nigeria (NOUN) using Abeokuta study center. Survey research method was adopted for this study. A questionnaire was designed and used to collect data for this study. A sample of 150 respondents was randomly selected from the final year students in the six schools of the…

  1. 75 FR 65377 - Notice of Public Meeting for the National Park Service (NPS) Alaska Region's Subsistence Resource...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... Resource Commission (SRC) program. SUMMARY: The Gates of the Arctic National Park SRC will meet to develop.... Gates of the Arctic National Park SRC Meeting Date and Location: The Gates of the Arctic National Park... meeting may end early if all business is completed. For Further Information On the Gates of the Arctic...

  2. Genetic diversity analysis of fruit characteristics of hawthorn germplasm.

    PubMed

    Su, K; Guo, Y S; Wang, G; Zhao, Y H; Dong, W X

    2015-12-07

    One hundred and six accessions of hawthorn intraspecific resources, from the National Germplasm Repository at Shenyang, were subjected to genetic diversity and principal component analysis based on evaluation data of 15 fruit traits. Results showed that the genetic diversity of hawthorn fruit traits varied. Among the 15 traits, the fruit shape variable coefficient had the most obvious evaluation, followed by fruit surface state, dot color, taste, weight of single fruit, sepal posture, peduncle form, and metula traits. These are the primary traits by which hawthorn could be classified in the future. The principal component demonstrated that these traits are the most influential factors of hawthorn fruit characteristics.

  3. Remote sensing inputs to National Model Implementation Program for water resources quality improvement

    NASA Technical Reports Server (NTRS)

    Eidenshink, J. C.; Schmer, F. A.

    1979-01-01

    The Lake Herman watershed in southeastern South Dakota has been selected as one of seven water resources systems in the United States for involvement in the National Model Implementation Program (MIP). MIP is a pilot program initiated to illustrate the effectiveness of existing water resources quality improvement programs. The Remote Sensing Institute (RSI) at South Dakota State University has produced a computerized geographic information system for the Lake Herman watershed. All components necessary for the monitoring and evaluation process were included in the data base. The computerized data were used to produce thematic maps and tabular data for the land cover and soil classes within the watershed. These data are being utilized operationally by SCS resource personnel for planning and management purposes.

  4. The Relationship between Conservation Policy and Aquatic Genetic Resources. In: T.R. Tiersch and C.C. Green (eds.) Cryopreservation in Aquatic Species, 2nd Edition. World Aquaculture Society, Baton Rouge, LA.

    USDA-ARS?s Scientific Manuscript database

    Globally there is an increased awareness of how important genetic resources are for all forms of agriculture. This awareness has resulted in questions concerning the policies countries and the international community should pursue to ensure the sustainable use of diverse genetic resources. For aquac...

  5. An Integrated Library Platform: Wales' Approach to Delivering Digital Information and Resources Nationally

    ERIC Educational Resources Information Center

    Bevan, Paul; Tyler, Alyson

    2009-01-01

    Purpose: This paper aims to outline the developments and strategies employed to supply online library services in Wales through a national platform: library.wales.org These services include: the "Cat Cymru" cross-catalogue search, centrally procured subscription resources and local library microsites. Design/methodology/approach: The…

  6. New generation pharmacogenomic tools: a SNP linkage disequilibrium Map, validated SNP assay resource, and high-throughput instrumentation system for large-scale genetic studies.

    PubMed

    De La Vega, Francisco M; Dailey, David; Ziegle, Janet; Williams, Julie; Madden, Dawn; Gilbert, Dennis A

    2002-06-01

    Since public and private efforts announced the first draft of the human genome last year, researchers have reported great numbers of single nucleotide polymorphisms (SNPs). We believe that the availability of well-mapped, quality SNP markers constitutes the gateway to a revolution in genetics and personalized medicine that will lead to better diagnosis and treatment of common complex disorders. A new generation of tools and public SNP resources for pharmacogenomic and genetic studies--specifically for candidate-gene, candidate-region, and whole-genome association studies--will form part of the new scientific landscape. This will only be possible through the greater accessibility of SNP resources and superior high-throughput instrumentation-assay systems that enable affordable, highly productive large-scale genetic studies. We are contributing to this effort by developing a high-quality linkage disequilibrium SNP marker map and an accompanying set of ready-to-use, validated SNP assays across every gene in the human genome. This effort incorporates both the public sequence and SNP data sources, and Celera Genomics' human genome assembly and enormous resource ofphysically mapped SNPs (approximately 4,000,000 unique records). This article discusses our approach and methodology for designing the map, choosing quality SNPs, designing and validating these assays, and obtaining population frequency ofthe polymorphisms. We also discuss an advanced, high-performance SNP assay chemisty--a new generation of the TaqMan probe-based, 5' nuclease assay-and high-throughput instrumentation-software system for large-scale genotyping. We provide the new SNP map and validation information, validated SNP assays and reagents, and instrumentation systems as a novel resource for genetic discoveries.

  7. Genetic Influences on Language, Reading, and Mathematics Skills in a National Sample: An Analysis Using the National Longitudinal Survey of Youth

    ERIC Educational Resources Information Center

    Hart, Sara A.; Petrill, Stephen A.; Kamp Dush, Claire M.

    2010-01-01

    Purpose: The present study had two purposes: provide an illustration of use of the National Longitudinal Survey of Youth 1979 Children's (CNLSY; U.S. Department of Labor, 2009) database and use the database to seek convergent evidence regarding the magnitude and significance of genetic effects influencing low and typical performers on measures of…

  8. Applied reproductive technologies and genetic resource banking for amphibian conservation.

    PubMed

    Kouba, Andrew J; Vance, Carrie K

    2009-01-01

    As amphibian populations continue to decline, both government and non-government organisations are establishing captive assurance colonies to secure populations deemed at risk of extinction if left in the wild. For the most part, little is known about the nutritional ecology, reproductive biology or husbandry needs of the animals placed into captive breeding programs. Because of this lack of knowledge, conservation biologists are currently facing the difficult task of maintaining and reproducing these species. Academic and zoo scientists are beginning to examine different technologies for maintaining the genetic diversity of founder populations brought out of the wild before the animals become extinct from rapidly spreading epizootic diseases. One such technology is genetic resource banking and applied reproductive technologies for species that are difficult to reproduce reliably in captivity. Significant advances have been made in the last decade for amphibian assisted reproduction including the use of exogenous hormones for induction of spermiation and ovulation, in vitro fertilisation, short-term cold storage of gametes and long-term cryopreservation of spermatozoa. These scientific breakthroughs for a select few species will no doubt serve as models for future assisted breeding protocols and the increasing number of amphibians requiring conservation intervention. However, the development of specialised assisted breeding protocols that can be applied to many different families of amphibians will likely require species-specific modifications considering their wide range of reproductive modes. The purpose of this review is to summarise the current state of knowledge in the area of assisted reproduction technologies and gene banking for the conservation of amphibians.

  9. [Formulation of technical specification for national survey of Chinese materia medica resources].

    PubMed

    Guo, Lan-Ping; Lu, Jian-Wei; Zhang, Xiao-Bo; Zhao, Run-Huai; Zhang, Ben-Gang; Sun, Li-Ying; Huang, Lu-Qi

    2013-04-01

    According to the process of the technical specification (TS) design for the fourth national survey of the Chinese materia medica resources (CMMR), we analyzed the assignment and objectives of the national survey and pointed out that the differences about CMMR management around China, the distribution of CMMR and their habitat, the economic and technological level, and even enthusiasm and initiative of the staff, etc. are the most difficult points for TS design. And we adopt the principle of combination of the mandatory and flexibility in TS design. We fixed the key points which would affect the quality of national survey first, then proposed the framework of TS which including 3 parts of organization and 11 parts of technique itself. The framework will serve and lead the TS preparation, which will not only provide an action standard to the national survey but will also have a profound influence to the popularization and application of the survey technology of CMMR. [Key words

  10. A National Research Council Evaluation of the Department of Energy's Marine and Hydrokinetic Resource Assessments

    NASA Astrophysics Data System (ADS)

    Glickson, D.; Holmes, K. J.; Cooke, D.

    2012-12-01

    Marine and hydrokinetic (MHK) resources are increasingly becoming part of energy regulatory, planning, and marketing activities in the U.S. and elsewhere. In particular, state-based renewable portfolio standards and federal production and investment tax credits have led to an increased interest in the possible deployment of MHK technologies. The Energy Policy Act of 2005 (Public Law 109-58) directed the Department of Energy (DOE) to estimate the size of the MHK resource base. In order to help DOE prioritize its overall portfolio of future research, increase the understanding of the potential for MHK resource development, and direct MHK device and/or project developers to locations of greatest promise, the DOE Wind and Water Power Program requested that the National Research Council (NRC) provide an evaluation of the detailed assessments being conducted by five individual resource assessment groups. These resource assessment groups were contracted to estimate the amount of extractable energy from wave, tidal, ocean current, ocean thermal energy conversion, and riverine resources. Performing these assessments requires that each resource assessment group estimate the average power density of the resource base, as well as the basic technology characteristics and spatial and temporal constituents that convert power into electricity for that resource. The NRC committee evaluated the methodologies, technologies, and assumptions associated with each of these resource assessments. The committee developed a conceptual framework for delineating the processes used to develop the assessment results requested by the DOE, with definitions of the theoretical, technical, and practical resource to clarify elements of the overall resource assessment process. This allowed the NRC committee to make a comparison of different methods, terminology, and processes among the five resource assessment groups. The committee concluded that the overall approach taken by the wave resource and

  11. 77 FR 47592 - Umatilla National Forest, Columbia County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ...The Umatilla National Forest, Columbia County Resource Advisory Committee will meet in Dayton, Washington as authorized under the Secure Rural Schools and Community Self-Determination Act. Purpose of the meeting will be to monitor projects being implemented under Public Law 110-343 and if authorized by the Secretary of Agriculture by the meeting date, to review and recommend projects to be funded under Public Law 112-141. This meeting is open to the public.

  12. Potential mineral resources, Payette National Forest, Idaho: description and probabilistic estimation

    USGS Publications Warehouse

    Bookstrom, Arthur A.; Johnson, Bruce R.; Cookro, Theresa M.; Lund, Karen; Watts, Kenneth C.; King, Harley D.; Kleinkopf, Merlin D.; Pitkin, James A.; Sanchez, J. David; Causey, J. Douglas

    1998-01-01

    The Payette National Forest (PNF), in west-central Idaho, is geologically diverse and contains a wide variety of mineral resources. Mineral deposit types are grouped into locatable, leasable, and salable categories. The PNF has substantial past production and identified resources of locatable commodities, including gold, silver, copper, zinc, tungsten, antimony, mercury, and opal. Minor lignitic coal is the only leasable mineral resource known to be present in the PNF. Resources of salable commodities in the PNF include sand-and-gravel, basalt for crushed-rock aggregate, and minor gypsum. Locatable mineral resources are geographically divided between eastern and western parts of the PNF. The western PNF lies west of the Riggins-to-Cascade highway (US 95 - Idaho 55), and the eastern PNF is east of that highway. The western and eastern parts of the PNF are geologically distinctive and have different types of locatable mineral deposits, so their locatable mineral resources are described separately. Within the western and eastern parts of the PNF, locatable deposit types generally are described in order of decreasing geologic age. An expert panel delineated tracts considered geologically permissive and (or) favorable for the occurrence of undiscovered mineral deposits of types that are known to be present within or near the PNF. The panel also estimated probabilities for undiscovered deposits, and used numerical simulation, based on tonnage-grade distribution models, to derive estimates of in-situ metals contained. These estimates are summarized in terms of mean and median measures of central tendency. Most grade and tonnage distributions appear to be log-normal, with the median lower than the mean. Inasmuch as the mean is influenced by the largest deposits in the model tonnage-grade distribution, the median provides a lower measure of central tendency and a more conservative estimation of undiscovered resources.

  13. Educational Equity and Adequacy for Disadvantaged Minority Students: School and Teacher Resource Gaps toward National Mathematics Proficiency Standard

    ERIC Educational Resources Information Center

    Lee, Jaekyung

    2012-01-01

    This study addresses the issue of educational inadequacy and inequity for disadvantaged minority students. It estimates desired national standards and examines interrelated gaps in key school-teacher resources and mathematics achievement by linking national education data sets (National Assessment of Educational Progress [NAEP], Common Core of…

  14. Citizen Scientists Contribute National-Scale Phenology Data for Science, Conservation and Resource Management

    NASA Astrophysics Data System (ADS)

    Weltzin, J. F.; Rosemartin, A.; Crimmins, T. M.; Posthumus, E.

    2015-12-01

    The USA National Phenology Network (USA-NPN; www.usanpn.org) serves science and society by promoting a broad understanding of plant and animal phenology and the relationships among phenological patterns and all aspects of environmental change. Data maintained by USA-NPN is being used for applications related to science, conservation and resource management. The majority of the data have been provided by "citizen scientists" participating in a national-scale, multi-taxa phenology observation program, Nature's Notebook. Since 2008, more than 5,500 active participants registered with Nature's Notebook have contributed over 5.5 million observation records for plants and animals. This presentation will demonstrate several types of questions that can be addressed by engaging citizen scientists in a standardized national monitoring system focused on field observations of biodiversity. Because the proof is often in the pudding, we will feature a diversity of recently published studies, but will also highlight several new and ongoing local- to continental-scale projects. Projects include continental bioclimatic indices, regional assessments of historical and potential future trends in phenology, sub-regional assessments of temperate deciduous forest response to recent variability in spring-time heat accumulation, state- and management unit- level foci on spatio-temporal variation in organismal activity at both the population and community level, and local monitoring for invasive species detection across platforms from ground to satellite. Additional data-mining and exploration by interested researchers and/or resource managers will likely further demonstrate the value of these data. The bottom line is that "citizen science" represents a viable approach to collect data across spatiotemporal scales often unattainable to research scientists under typical resource constraints.

  15. Genetics Home Reference: Pompe disease

    MedlinePlus

    ... Genetic Testing (2 links) Genetic Testing Registry: Glycogen storage disease type II, infantile Genetic Testing Registry: Glycogen storage disease, type II Other Diagnosis and Management Resources ( ...

  16. Amarillo National Resource Center for Plutonium quarterly technical progress report, August 1, 1997--October 31, 1997

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    This report summarizes activities of the Amarillo National Resource Center for Plutonium during the quarter. The report describes the Electronic Resource Library; DOE support activities; current and future environmental health and safety programs; pollution prevention and pollution avoidance; communication, education, training, and community involvement programs; and nuclear and other material studies, including plutonium storage and disposition studies.

  17. Looking back to move forward: collaborative planning to revise the Green Mountain and Finger Lakes National Forests land and resource management plans

    Treesearch

    Michael J. Dockry

    2015-01-01

    The United States Department of Agriculture Forest Service (Forest Service) manages 154 national forests and 20 grasslands in 44 states and Puerto Rico. National Forest Land and Resource Management Plans (forest plans) form the basis for land and resource management of national forests in the United States. For more than a decade the Forest Service has been attempting...

  18. Timber resource statistics for all forest land, except national forests, in eastern Oregon.

    Treesearch

    Donald R. Gedney; Patricia M. Bassett; Mary A. Mei

    1989-01-01

    This report summarizes a 1987 timber resource inventory of all forest land, except National Forests, in the 17 counties (Baker, Crook, Deschutes, Gilliam, Grant, Harney, Jefferson, Klamath, Lake, Malheur, Morrow, Sherman, Umatilla, Union, Wallowa, Wasco, and Wheeler Counties) in eastern Oregon. Detailed tables of forest area, timber volume, growth, mortality, and...

  19. Assessment and Evaluation of National Human Resource Development System Competitiveness in Emerging Countries

    ERIC Educational Resources Information Center

    Oh, HunSeok; Seo, DongIn; Kim, JuSeuk; Yoo, SangOk; Seong, HeeChang

    2015-01-01

    This study assessed and evaluated the competitiveness of national human resource development (NHRD) systems in emerging countries with potential for growth. The literature on emerging countries and NHRD systems was reviewed. The study developed a model mechanism with forty-one indices and nine sub-components for the NHRD system assessment in…

  20. Integrating geo-referenced multiscale and multidisciplinary data for the management of biodiversity in livestock genetic resources.

    PubMed

    Joost, S; Colli, L; Baret, P V; Garcia, J F; Boettcher, P J; Tixier-Boichard, M; Ajmone-Marsan, P

    2010-05-01

    In livestock genetic resource conservation, decision making about conservation priorities is based on the simultaneous analysis of several different criteria that may contribute to long-term sustainable breeding conditions, such as genetic and demographic characteristics, environmental conditions, and role of the breed in the local or regional economy. Here we address methods to integrate different data sets and highlight problems related to interdisciplinary comparisons. Data integration is based on the use of geographic coordinates and Geographic Information Systems (GIS). In addition to technical problems related to projection systems, GIS have to face the challenging issue of the non homogeneous scale of their data sets. We give examples of the successful use of GIS for data integration and examine the risk of obtaining biased results when integrating datasets that have been captured at different scales.

  1. 76 FR 72424 - Submission for OMB Review; Comment Request Information Program on the Genetic Testing Registry

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Submission for OMB Review... Office of Management and Budget (OMB) a request to review and approve the information collection listed... more than 2,000 genetic conditions are available; however, there is no centralized public resource that...

  2. China's human resources for maternal and child health: a national sampling survey.

    PubMed

    Ren, Zhenghong; Song, Peige; Theodoratou, Evropi; Guo, Sufang; An, Lin

    2015-12-16

    In order to achieve the Millennium Development Goals (MDG) 4 and 5, the Chinese Government has invested greatly in improving maternal and child health (MCH) with impressive results. However, one of the most important barriers for further improvement is the uneven distribution of MCH human resources. There is little information about the distribution, quantity and capacity of the Chinese MCH human resources and we sought to investigate this. Cities at prefectural level were selected by random cluster sampling. All medical and health institutions providing MCH-related services in the sampled areas were investigated using a structured questionnaire. The data were weighted based on the proportion of the sampled districts/cities. Amount, proportions and numbers per 10,000 population of MCH human resources were estimated in order to reveal the quantity of the Chinese MCH human resources. The capacity of MCH human resources was evaluated by analyzing data on the education level and professional skills of the staff. There were 77,248 MCH workers in China in 2010. In general, 67.6% and 71.9% of the women's and children's health care professionals had an associate degree or higher, whereas around 30% had only high-school or lower degrees. More than 40% of the women's health workers were capable of providing skilled birth attendance, but these proportions varied between different institutions and locations. Evidence from this study highlights that Chinese MCH human resources are not in shortage in the national level. However, the quantity and capacity of MCH human resources are not evenly distributed among different institutions and locations. Finally there is a need in the improvement of the MCH services by improving the quality of MCH human resources.

  3. Caribbean Equal Access Program: HIV/AIDS Information Resources from the National Library of Medicine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nancy Dancy, NLM, and Wilma Templin-Branner, ORISE

    2009-01-01

    As the treatment and management of HIV/AIDS continues to evolve with new scientific breakthroughs, treatment discoveries, and management challenges, it is difficult for people living with HIV/AIDS and those who care for them to keep up with the latest information on HIV/AIDS prevention, treatment, and research. The National Library of Medicine, of the National Institutes of Health, has a wealth of health information resources freely available on the Internet to address these needs.

  4. Geologic framework for the national assessment of carbon dioxide storage resources: Permian and Palo Duro Basins and Bend Arch-Fort Worth Basin: Chapter K in Geologic framework for the national assessment of carbon dioxide storage resources

    USGS Publications Warehouse

    Merrill, Matthew D.; Slucher, Ernie R.; Roberts-Ashby, Tina L.; Warwick, Peter D.; Blondes, Madalyn S.; Freeman, P.A.; Cahan, Steven M.; DeVera, Christina A.; Lohr, Celeste D.; Warwick, Peter D.; Corum, Margo D.

    2015-01-01

    The U.S. Geological Survey has completed an assessment of the potential geologic carbon dioxide storage resource in the onshore areas of the United States. To provide geological context and input data sources for the resources numbers, framework documents are being prepared for all areas that were investigated as part of the national assessment. This report is the geologic framework document for the Permian and Palo Duro Basins, the combined Bend arch-Fort Worth Basin area, and subbasins therein of Texas, New Mexico, and Oklahoma. In addition to a summarization of the geology and petroleum resources of studied basins, the individual storage assessment units (SAUs) within the basins are described and explanations for their selection are presented. Though appendixes in the national assessment publications include the input values used to calculate the available storage resource, this framework document provides only the context and source of inputs selected by the assessment geologists. Spatial files of boundaries for the SAUs herein, as well as maps of the density of known well bores that penetrate the SAU seal, are available for download with the release of this report.

  5. 2008 High-Flow Experiment at Glen Canyon Dam Benefits Colorado River Resources in Grand Canyon National Park

    USGS Publications Warehouse

    Melis, Theodore S.; Topping, David J.; Grams, Paul E.; Rubin, David M.; Wright, Scott A.; Draut, Amy E.; Hazel, Joseph E.; Ralston, Barbara E.; Kennedy, Theodore A.; Rosi-Marshall, Emma; Korman, Josh; Hilwig, Kara D.; Schmit, Lara M.

    2010-01-01

    On March 5, 2008, the Department of the Interior began a 60-hour high-flow experiment at Glen Canyon Dam, Arizona, to determine if water releases designed to mimic natural seasonal flooding could be used to improve downstream resources in Glen Canyon National Recreation Area and Grand Canyon National Park. U.S. Geological Survey (USGS) scientists and their cooperators undertook a wide range of physical and biological resource monitoring and research activities before, during, and after the release. Scientists sought to determine whether or not high flows could be used to rebuild Grand Canyon sandbars, create nearshore habitat for the endangered humpback chub, and benefit other resources such as archaeological sites, rainbow trout, aquatic food availability, and riverside vegetation. This fact sheet summarizes research completed by January 2010.

  6. The Community College and the Human Resources Development Council: Toward a National Training Strategy for the United States.

    ERIC Educational Resources Information Center

    Eskow, Seymour

    The key to economic renewal in the United States is a national human resources development strategy in which community colleges assume the national training role. This national strategy must recognize changes in the American economy and workforce, such as a more educated labor force, the demographics of developing countries, the increased…

  7. [The role of S.N. Davidenkov School in becoming of national neuro-genetics].

    PubMed

    Fando, R A

    2013-01-01

    The article considers the biography of prominent Russian scientist, full member of the Academy of medical sciences of the USSR Sergei Nikolayevitch Davidenkov studying genetics of nervous diseases. The main directions of activities of the scientific school created by him are analyzed. The significance of this school in development of biology and medicine is established. The staff organizational structure, specificity of considered scientific school are established. The role of leader in organization of non-formal research community and development of scientific program is demonstrated. It is marked that in solution of many fundamental and practical tasks of medical genetics an immense merit belonged to scientific schools as a "strong side" of national science of the first half of XX century.

  8. Public Awareness of Direct-to-Consumer Genetic Tests: Findings from the 2013 U.S. Health Information National Trends Survey.

    PubMed

    Agurs-Collins, Tanya; Ferrer, Rebecca; Ottenbacher, Allison; Waters, Erika A; O'Connell, Mary E; Hamilton, Jada G

    2015-12-01

    Although the availability of direct-to-consumer (DTC) genetic testing has increased in recent years, the general public's awareness of this testing is not well understood. This study examined levels of public awareness of DTC genetic testing, sources of information about testing, and psychosocial factors associated with awareness of testing in the USA. Data were obtained from the nationally representative 2013 U.S. Health Information National Trends Survey. Guided by a social-cognitive conceptual framework, univariable and multivariable logistic regressions were conducted to identify factors associated with awareness of DTC genetic tests. Of 3185 participants, 35.6% were aware of DTC genetic tests, with the majority learning about these tests through radio, television, and the Internet. In the final adjusted model, participants with annual incomes of $99,999 or less had lower odds of being aware of DTC genetic testing (ORs ranging from 0.46-0.61) than did those participants with incomes of $100,000 or more. The odds of awareness of DTC genetic tests were significantly higher for those who actively seek cancer information (OR=1.91, 95% CI=1.36-2.69), use the Internet (OR=1.81, 95% CI=1.05-3.13), and have high numeracy skills (OR=1.67, 95% CI=1.17-2.38). It will be critical for healthcare researchers and practitioners to understand predictors and consequences of the public's awareness of DTC genetic tests, as well as how such awareness may translate into DTC genetic testing uptake, health behavior change, and ultimately disease prevention.

  9. 48 CFR 1352.237-73 - Foreign national visitor and guest access to departmental resources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Regulations System DEPARTMENT OF COMMERCE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text... resources. As prescribed in 48 CFR 1337.110-70 (e), insert the following clause: Foreign National Visitor...; Bureau of Industry and Security Export Administrative Regulations Part 734, and [insert operating unit...

  10. An economic evaluation of a genetic screening program for Tay-Sachs disease.

    PubMed Central

    Nelson, W B; Swint, J M; Caskey, C T

    1978-01-01

    The resolution of policy questions relating to medical genetic screening programs will not be without considerable difficulty. Examples include such issues as the optimal degree of screening program expansion, the relative values of screening for different genetic diseases, the appropriate sources of program funding (public vs. private), and the relative value of funding expanded genetic screening programs vs. research directed toward elimination of genetic traits themselves. Information on the net impact of the relevant alternatives is greatly needed, and this need will increase if the National Genetics Act receives funding approval. We have provided what is hopefully a contribution toward this end. While our analysis pertains to a specific disease and a specific screening program for that disease, the methodology is readily generalizable to other genetic diseases, as well as programs of any size or structure. Hopefully, this will serve to stimulate further research efforts that we believe are needed for the objective consideration of resource allocation alternatives. PMID:418675

  11. An economic evaluation of a genetic screening program for Tay-Sachs disease.

    PubMed

    Nelson, W B; Swint, J M; Caskey, C T

    1978-03-01

    The resolution of policy questions relating to medical genetic screening programs will not be without considerable difficulty. Examples include such issues as the optimal degree of screening program expansion, the relative values of screening for different genetic diseases, the appropriate sources of program funding (public vs. private), and the relative value of funding expanded genetic screening programs vs. research directed toward elimination of genetic traits themselves. Information on the net impact of the relevant alternatives is greatly needed, and this need will increase if the National Genetics Act receives funding approval. We have provided what is hopefully a contribution toward this end. While our analysis pertains to a specific disease and a specific screening program for that disease, the methodology is readily generalizable to other genetic diseases, as well as programs of any size or structure. Hopefully, this will serve to stimulate further research efforts that we believe are needed for the objective consideration of resource allocation alternatives.

  12. Reye syndrome - resources

    MedlinePlus

    Resources - Reye syndrome ... The following organizations are good resources for information on Reye Syndrome : National Reye's Syndrome Foundation, Inc. -- www.reyessyndrome.org National Institute of Neurologic Disorders and Stroke -- www. ...

  13. Establishing a Twin Register: An Invaluable Resource for (Behavior) Genetic, Epidemiological, Biomarker, and 'Omics' Studies.

    PubMed

    Odintsova, Veronika V; Willemsen, Gonneke; Dolan, Conor V; Hottenga, Jouke-Jan; Martin, Nicholas G; Slagboom, P Eline; Ordoñana, Juan R; Boomsma, Dorret I

    2018-06-01

    Twin registers are wonderful research resources for research applications in medical and behavioral genetics, epidemiology, psychology, molecular genetics, and other areas of research. New registers continue to be launched all over the world as researchers from different disciplines recognize the potential to boost and widen their research agenda. In this article, we discuss multiple aspects that need to be taken into account when initiating a register, from its preliminary sketch to its actual development. This encompasses aspects related to the strategic planning and key elements of research designs, promotion and management of a twin register, including recruitment and retaining of twins and family members of twins, phenotyping, database organization, and collaborations between registers. We also present information on questions unique to twin registers and twin-biobanks, such as the assessment of zygosity by SNP arrays, the design of (biomarker) studies involving related participants, and the analyses of clustered data. Altogether, we provide a number of basic guidelines and recommendations for reflection when planning a twin register.

  14. Environmental Health and Toxicology Resources of the United States National Library of Medicine

    PubMed Central

    Hochstein, Colette; Arnesen, Stacey; Goshorn, Jeanne

    2009-01-01

    For over 40 years, the National Library of Medicine’s (NLM) Toxicology and Environmental Health Information Program (TEHIP) has worked to organize and to provide access to an extensive array of environmental health and toxicology resources. During these years, the TEHIP program has evolved from a handful of databases developed primarily for researchers to a broad range of products and services that also serve industry, students, and the general public. TEHIP’s resources include TOXNET® , a collection of databases, including online handbooks, bibliographic references, information on the release of chemicals in the environment, and a chemical dictionary. TEHIP also produces several resources aimed towards the general public, such as the Household Products Database , which helps users explore chemicals often found in common household products, and Tox Town® , an interactive guide to commonly encountered toxic substances, health, and the environment. This paper introduces some of NLM’s environmental health and toxicology resources. PMID:17915629

  15. National Aquatic Resource Surveys: Use of Geospatial data in their design and spatial prediction at non-monitored locations

    EPA Science Inventory

    The National Aquatic Resource Surveys (NARS) are four surveys conducted by the U.S. Environmental Protection Agency working in collaboration with states, tribal nations and other federal agencies. The surveys are conducted for lakes and reservoirs, streams, estuaries and intracoa...

  16. Genetic overlap between impulsivity and alcohol dependence: a large-scale national twin study.

    PubMed

    Khemiri, L; Kuja-Halkola, R; Larsson, H; Jayaram-Lindström, N

    2016-04-01

    Alcohol dependence is associated with increased levels of impulsivity, but the genetic and environmental underpinnings of this overlap remain unclear. The purpose of the current study was to investigate the degree to which genetic and environmental factors contribute to the overlap between alcohol dependence and impulsivity. Univariate and bivariate twin model fitting was conducted for alcohol dependence and impulsivity in a national sample of 16 819 twins born in Sweden from 1959 to 1985. The heritability estimate for alcohol dependence was 44% [95% confidence interval (CI) 31-57%] for males and 62% (95% CI 52-72%) for females. For impulsivity, the heritability was 33% (95% CI 30-36%) in males and females. The bivariate twin analysis indicated a statistically significant genetic correlation between alcohol dependence and impulsivity of 0.40 (95% CI 0.23-0.58) in males and 0.20 (95% CI 0.07-0.33) in females. The phenotypic correlation between alcohol dependence and impulsivity was 0.20 and 0.17 for males and females, respectively, and the bivariate heritability was 80% (95% CI 47-117%) for males and 53% (95% CI 19-86%) for females. The remaining variance in all models was accounted for by non-shared environmental factors. The association between alcohol dependence and impulsivity can be partially accounted for by shared genetic factors. The genetic correlation was greater in men compared with women, which may indicate different pathways to the development of alcohol dependence between sexes. The observed genetic overlap has clinical implications regarding treatment and prevention, and partially explains the substantial co-morbidity between alcohol dependence and psychiatric disorders characterized by impulsive behaviour.

  17. Our living resources: A report to the nation on the distribution, abundance, and health of U.S. plants, animals, and ecosystems

    USGS Publications Warehouse

    LaRoe, Edward T.; Farris, Gaye S.; Puckett, Catherine E.; Doran, Peter D.; Mac, Michael J.

    1995-01-01

    This report on the distribution, abundance, and health of our nation's biological resources is the first product of the National Biological Service’s Status and Trends Program. This information has many potential uses: it can document successful management efforts so resource managers will know what has worked well; it can identify problems so managers can take early action to restore the resource in the most cost-efficient manner; and it can be used to highlight areas where additional research is needed, such as to determine why certain ecological changes are occurring. This report will also be useful to teachers, students, journalists, and citizens in general who are interested in national resource issues.Another purpose of this report is to help identify gaps in existing resource inventory and monitoring programs. It contains information collected by a variety of existing research and monitoring efforts by scientists in the National Biological Service, other federal and state agencies, academia, and the private sector. The programs that produced the information in this document were not developed in a coordinated fashion to produce an integrated, comprehensive picture of the status and trends of our nation’s resources; rather, each was developed for its own particular purpose, usually to help manage a specific resource. Thus, even though articles vary greatly in scope, design, and purpose, this report has identified and attempted to combine many of the existing information sources into a broad picture of the condition of our resources. In the future, these sources will be complemented by additional information from other sources - such as state agencies and other inventory and monitoring studies - to fill in the gaps of knowledge and to provide a more complete understanding of the status of our living resources.

  18. Genetics Home Reference: myasthenia gravis

    MedlinePlus

    ... ventilation assistance. This respiratory failure, called a myasthenic crisis, may be triggered by stresses such as infections ... be inherited? More about Inheriting Genetic Conditions Diagnosis & Management Resources Genetic Testing (2 links) Genetic Testing Registry: ...

  19. Genetics Home Reference: hereditary angioedema

    MedlinePlus

    ... 000 people. Type I is the most common, accounting for 85 percent of cases. Type II occurs ... be inherited? More about Inheriting Genetic Conditions Diagnosis & Management Resources Genetic Testing (3 links) Genetic Testing Registry: ...

  20. Genetics Home Reference: multiminicore disease

    MedlinePlus

    ... are less common than the classic form, together accounting for about 25 percent of all cases. The ... be inherited? More about Inheriting Genetic Conditions Diagnosis & Management Resources Genetic Testing (5 links) Genetic Testing Registry: ...

  1. Sunflower genetic, genomic, and ecological resources

    USDA-ARS?s Scientific Manuscript database

    Long a major focus of genetic research and breeding, sunflowers (Helianthus) are emerging as an increasingly important experimental system for ecological and evolutionary studies. Here we review the various attributes of wild and domesticated sunflowers that make them valuable for ecological experim...

  2. National Uranium Resource Evaluation: Durango Quadrangle, Colorado

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Theis, N.J.; Madson, M.E.; Rosenlund, G.C.

    1981-06-01

    The Durango Quadrangle (2/sup 0/), Colorado, was evaluated using National Uranium Resource Evaluation criteria to determine environments favorable for uranium deposits. General reconnaissance, geologic and radiometric investigations, was augmented by detailed surface examination and radiometric and geochemical studies in selected areas. Eight areas favorable for uranium deposits were delineated. Favorable geologic environments include roscoelite-type vanadium-uranium deposits in the Placerville and Barlow Creek-Hermosa Creek districts, sandstone uranium deposits along Hermosa Creek, and vein uranium deposits in the Precambrian rocks of the Needle Mountains area and in the Paleozoic rocks of the Tuckerville and Piedra River Canyon areas. The major portions ofmore » the San Juan volcanic field, the San Juan Basin, and the San Luis Basin within the quadrangle were judged unfavorable. Due to lack of information, the roscoelite belt below 1000 ft (300 m), the Eolus Granite below 0.5 mi (0.8 km), and the Lake City caldera are unevaluated. The Precambrian Y melasyenite of Ute Creek and the Animas Formation within the Southern Ute Indian Reservation are unevaluated due to lack of access.« less

  3. Visitor experience and resource protection framework in the National Park System: rationale, current status, and future direction

    Treesearch

    Marilyn Hof; David W. Lime

    1997-01-01

    The Visitor Experience and Resource Protection (VERP) framework was developed by the National Park Service to address carrying capacity questions associated with visitation-related resource impacts and impacts to the quality of visitor experiences. The framework can be applied as part of a park’s general management planning process (general management plans, GMPs), to...

  4. 77 FR 47593 - Umatilla National Forest, Southeast Washington Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ...The Umatilla National Forest, Southeast Washington Resource Advisory Committee will meet in Pomeroy, Washington as authorized under the Secure Rural Schools and Community Self-Determination Act, as amended, in compliance with the Federal Advisory Committee Act. Purpose of the meeting will be to monitor projects being implemented under Public Law 110-343 and if authorized by the Secretary of Agriculture by the meeting date, to review and recommend projects to be funded under Public Law 112-141. This meeting is open to the public.

  5. Genetics Home Reference: Gillespie syndrome

    MedlinePlus

    ... the prognosis of a genetic condition? Genetic and Rare Diseases Information Center Frequency The prevalence of Gillespie syndrome ... Developmental Disabilities Health Topic: Eye Diseases Genetic and Rare Diseases Information Center (1 link) Gillespie syndrome Educational Resources ( ...

  6. Assessment of mineral resource tracts in the Chugach National Forest, Alaska

    USGS Publications Warehouse

    Nelson, Steven W.; Miller, Marti L.

    2000-01-01

    Locatable minerals have been produced from the Chugach National Forest (CNF) for nearly 100 years. Past gold production has come from the Kenai Peninsula and the Girdwood, Port Wells, and Valdez areas. Copper and by-product gold and silver have been produced from mines at Ellamar, on Latouche Island, and near Valdez. Many of the past-producing properties were not mined out and contain significant inferred reserves of gold, copper, lead, zinc, and silver. This report outlines mineral resource areas (tracts) that contain both identified and undiscovered mineral resources. These tracts were drawn on the basis of one or more of the following criteria: (1) geochemical anomalies, (2) favorable geologic units, (3) presence of mines, prospects or mineral occurrences, and (4) geophysical anomalies. Bliss (1989) used six mineral deposit models to describe the types of deposits known from the CNF. Of these deposit types, only four are sufficiently known and defined in the CNF to be suitable for consideration in outlining and ranking of mineral resource tracts; these deposit types are: (1) Cyprus-type massive sulfide, (2) Chugach-type low-sulfide goldquartz veins, (3) placer gold, and (4) polymetallic vein. The U.S. Bureau of Mines indicated that most of the inferred mineral reserves in the CNF would not be economic to produce under current prices. Small-scale placer gold operations are a possible exception. Other known resources that have recorded past production (oil, coal, rock, sand, and gravel) are not addressed in this report.

  7. Amarillo National Resource Center for Plutonium. Quarterly technical progress report, May 1, 1997--July 31, 1997

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    Progress summaries are provided from the Amarillo National Center for Plutonium. Programs include the plutonium information resource center, environment, public health, and safety, education and training, nuclear and other material studies.

  8. A formalized approach to making effective natural resource management decisions for Alaska National Parks

    USGS Publications Warehouse

    MacCluskie, Margaret C.; Romito, Angela; Peterson, James T.; Lawler, James P.

    2015-01-01

    A fundamental goal of the National Park Service (NPS) is the long-term protection and management of resources in the National Park System. Reaching this goal requires multiple approaches, including the conservation of essential habitats and the identification and elimination of potential threats to biota and habitats. To accomplish these goals, the NPS has implemented the Alaska Region Vital Signs Inventory and Monitoring (I&M) Program to monitor key biological, chemical, and physical components of ecosystems at more than 270 national parks. The Alaska Region has four networks—Arctic, Central, Southeast, and Southwest. By monitoring vital signs over large spatial and temporal scales, park managers are provided with information on the status and trajectory of park resources as well as a greater understanding and insight into the ecosystem dynamics. While detecting and quantifying change is important to conservation efforts, to be useful for formulating remedial actions, monitoring data must explicitly relate to management objectives and be collected in such a manner as to resolve key uncertainties about the dynamics of the system (Nichols and Williams 2006). Formal decision making frameworks (versus more traditional processes described below) allow for the explicit integration of monitoring data into decision making processes to improve the understanding of system dynamics, thereby improving future decisions (Williams 2011).

  9. An ultra-high-density map as a community resource for discerning the genetic basis of quantitative traits in maize

    USDA-ARS?s Scientific Manuscript database

    In this study, we generated a linkage map containing 1,151,856 high quality SNPs between Mo17 and B73, which were verified in the maize intermated B73'×'Mo17 (IBM) Syn10 population. This resource is an excellent complement to existing maize genetic maps available in an online database (iPlant, http:...

  10. [The biobank of the German National Cohort as a resource for epidemiologic research].

    PubMed

    Wichmann, H-Erich; Hörlein, Andreas; Ahrens, Wolfgang; Nauck, Matthias

    2016-03-01

    The linkage of high-quality biosamples with detailed data from medical examinations, questionnaires and interviews offers great opportunities for research. This is particularly true for large-scale prospective epidemiological studies with long observation periods, like the German National Cohort (GNC). The modalities of collecting, processing and storing biosamples of high quality and with a high throughput, as well as ethical aspects are described using the GNC as an example. For the GNC, 200,000 randomly selected adults will be recruited by 18 study centres and will be followed up for 20-30 years. In addition to the extensive basic examination protocol, followed by reassessment examinations and follow-up questionnaires, the biorepository is a cornerstone of the GNC. The GNC biorepository will comprise more than 20 million aliquots of plasma, serum, erythrocytes, lymphocytes, urine, saliva, nasal swabs and stool. Preanalytics and aliquoting are performed locally in the study centres and are highly standardised and extensively automated. All samples are stored at - 80 and - 180 °C, respectively. A laboratory information system documents all processing steps and storage locations. Access to data and biosamples will be granted to researchers within and outside Germany after completion of the baseline recruitment (i.e. from 2018 onwards). Experience with already existing epidemiological biobanks shows impressive results, especially with regard to genetic research, as well as post-genomics (e.g. transcriptomics, metabolomics, epigenomics). Previous success stories explain the strongly increased demand for data and biosamples from the population. Thus the GNC will provide an important resource for biomedical research in the future.

  11. Prenatal Testing for Adult-Onset Conditions: the Position of the National Society of Genetic Counselors.

    PubMed

    Hercher, Laura; Uhlmann, Wendy R; Hoffman, Erin P; Gustafson, Shanna; Chen, Kelly M

    2016-12-01

    Advances in genetic testing and the availability of such testing in pregnancy allows prospective parents to test their future child for adult-onset conditions. This ability raises several complex ethical issues. Prospective parents have reproductive rights to obtain information about their fetus. This information may or may not alter pregnancy management. These rights can be in conflict with the rights of the future individual, who will be denied the right to elect or decline testing. This paper highlights the complexity of these issues, details discussions that went into the National Society of Genetic Counselors (NSGC) Public Policy Task Force's development of the Prenatal testing for Adult-Onset Conditions position statement adopted in November 2014, and cites relevant literature on this topic through December 2015. Issues addressed include parental rights and autonomy, rights of the future child, the right not to know, possible adverse effects on childhood and the need for genetic counseling. This paper will serve as a reference to genetic counselors and healthcare professionals when faced with this situation in clinical practice.

  12. Complex Households and the Distribution of Multiple Resources in Later Life: Findings From a National Survey.

    PubMed

    Kim, Juyeon; Waite, Linda J

    2016-02-01

    The availability of social and financial resources has profound implications for health and well-being in later life. Older adults often share resources with others who live with them, sometimes in households including relatives or friends. We examine differences in social support, social connections, money, and the household environment across types of living arrangements, develop hypotheses from two theoretical perspectives, one focusing on obligations toward kin, and one focused on social exchange within households, and test them using data from the National Social Life, Health, and Aging Project. We find that availability of resources is not consistently associated with the presence of grandchildren and other young relatives, but often differs with presence of other adults. These findings suggest that a single type of resource tells us little about the distribution of the resources of older adults, and call on us to examine multiple resources simultaneously. © The Author(s) 2015.

  13. Complex Households and the Distribution of Multiple Resources in Later Life: Findings from A National Survey

    PubMed Central

    Kim, Juyeon; Link, Arts; Waite, Linda

    2016-01-01

    The availability of social and financial resources has profound implications for health and well-being in later life. Older adults often share resources with others who live with them, sometimes in households including relatives or friends. We examine differences in social support, social connections, money, and the household environment across types of living arrangements, develop hypotheses from two theoretical perspectives, one focusing on obligations toward kin, and one focused on social exchange within households, and test them using data from the National Social Life, Health, and Aging Project. We find that availability of resources is not consistently associated with the presence of grandchildren and other young relatives, but often differs with presence of other adults. These findings suggest that a single type of resource tells us little about the distribution of the resources of older adults, and call on us to examine multiple resources simultaneously. PMID:25904682

  14. Assess, Map and Predict the Integrity, Resilience, and Recovery Potential of the Nation's Water Resources

    EPA Science Inventory

    This project will provide knowledge and adaptive management techniques to both maintain healthy waters and to improve degraded systems. It will provide scientific support for the National Aquatic Resource Surveys. Results will provide a basis for informed decision making and tool...

  15. Genetic Diversity Strategy for the Management and Use of Rubber Genetic Resources: More than 1,000 Wild and Cultivated Accessions in a 100-Genotype Core Collection

    PubMed Central

    Cerqueira-Silva, Carlos Bernardo Moreno; Silva, Carla Cristina; Mantello, Camila Campos; Conson, Andre Ricardo Oliveira; Vianna, João Paulo Gomes; Zucchi, Maria Imaculada; Scaloppi Junior, Erivaldo José; Fialho, Josefino de Freitas; de Moraes, Mario Luis Teixeira; Gonçalves, Paulo de Souza; de Souza, Anete Pereira

    2015-01-01

    The rubber tree [Hevea brasiliensis (Willd. ex Adr. de Juss.) Muell. Arg.] is the only plant species worldwide that is cultivated for the commercial production of natural rubber. This study describes the genetic diversity of the Hevea spp. complex that is available in the main ex situ collections of South America, including Amazonian populations that have never been previously described. Genetic data were analyzed to determine the genetic structure of the wild populations, quantify the allelic diversity and suggest the composition of a core collection to capture the maximum genetic diversity within a minimal sample size. A total of 1,117 accessions were genotyped with 13 microsatellite markers. We identified a total of 408 alleles, 319 of which were shared between groups and 89 that were private in different groups of accessions. In a population structure and principal component analysis, the level of clustering reflected a primary division into the following two subgroups: cluster 1, which consisted of varieties from the advanced breeding germplasm that originated from the Wickham and Mato Grosso accessions; and cluster 2, which consisted of the wild germplasm from the Acre, Amazonas, Pará and Rondônia populations and Hevea spp. The analyses revealed a high frequency of gene flow between the groups, with the genetic differentiation coefficient (GST) estimated to be 0.018. Additionally, no distinct separation among the H. brasiliensis accessions and the other species from Amazonas was observed. A core collection of 99 accessions was identified that captured the maximum genetic diversity. Rubber tree breeders can effectively utilize this core collection for cultivar improvement. Furthermore, such a core collection could provide resources for forming an association panel to evaluate traits with agronomic and commercial importance. Our study generated a molecular database that should facilitate the management of the Hevea germplasm and its use for subsequent genetic

  16. Molecular Genetic Testing in Reward Deficiency Syndrome (RDS): Facts and Fiction.

    PubMed

    Blum, Kenneth; Badgaiyan, Rajendra D; Agan, Gozde; Fratantonio, James; Simpatico, Thomas; Febo, Marcelo; Haberstick, Brett C; Smolen, Andrew; Gold, Mark S

    The Brain Reward Cascade (BRC) is an interaction of neurotransmitters and their respective genes to control the amount of dopamine released within the brain. Any variations within this pathway, whether genetic or environmental (epigenetic), may result in addictive behaviors or RDS, which was coined to define addictive behaviors and their genetic components. To carry out this review we searched a number of important databases including: Filtered: Cochrane Systematic reviews; DARE; Pubmed Central Clinical Quaries; National Guideline Clearinghouse and unfiltered resources: PsychINFO; ACP PIER; PsychSage; Pubmed/Medline. The major search terms included: dopamine agonist therapy for Addiction; dopamine agonist therapy for Reward dependence; dopamine antagonistic therapy for addiction; dopamine antagonistic therapy for reward dependence and neurogenetics of RDS. While there are many studies claiming a genetic association with RDS behavior, not all are scientifically accurate. Albeit our bias, this Clinical Pearl discusses the facts and fictions behind molecular genetic testing in RDS and the significance behind the development of the Genetic Addiction Risk Score (GARS PREDX ™), the first test to accurately predict one's genetic risk for RDS.

  17. Updates to the Cool Season Food Legume Genome Database: Resources for pea, lentil, faba bean and chickpea genetics, genomics and breeding

    USDA-ARS?s Scientific Manuscript database

    The Cool Season Food Legume Genome database (CSFL, www.coolseasonfoodlegume.org) is an online resource for genomics, genetics, and breeding research for chickpea, lentil,pea, and faba bean. The user-friendly and curated website allows for all publicly available map,marker,trait, gene,transcript, ger...

  18. Biobanking genetic material for agricultural animal species

    USDA-ARS?s Scientific Manuscript database

    Biobanking animal germplasm and tissues is a major component of conserving genetic resources. Effectively constructing such gene banks requires an understanding and evaluation of genetic resources, the ability to conserve various tissues through cryopreservation, and a robust information technology ...

  19. Investigations of Sample Stability in Water Chemistry Samples: Implications for the National Aquatic Resource Surveys

    EPA Science Inventory

    Water samples collected for the EPA's National Aquatic Resource Surveys (NARS) typically arrive at an analytical laboratory 2 or 3 days after collection (longer if collected from a remote location), at which point they are stabilized (filtration and/or acid preservation) until an...

  20. Conservation of indigenous cattle genetic resources in Southern Africa’s smallholder areas: turning threats into opportunities — A review

    PubMed Central

    Nyamushamba, G. B.; Mapiye, C.; Tada, O.; Halimani, T. E.; Muchenje, V.

    2017-01-01

    The current review focuses on characterization and conservation efforts vital for the development of breeding programmes for indigenous beef cattle genetic resources in Southern Africa. Indigenous African cattle breeds were identified and characterized using information from refereed journals, conference papers and research reports. Results of this current review reviewed that smallholder beef cattle production in Southern Africa is extensive and dominated by indigenous beef cattle strains adaptable to the local environment. The breeds include Nguni, Mashona, Tuli, Malawi Zebu, Bovino de Tete, Angoni, Landim, Barotse, Twsana and Ankole. These breeds have important functions ranging from provision of food and income to socio-economic, cultural and ecological roles. They also have adaptive traits ranging from drought tolerant, resistance to ticks and tick borne diseases, heat tolerance and resistance to trypanosomosis. Stakeholders in the conservation of beef cattle were also identified and they included farmers, national government, research institutes and universities as well as breeding companies and societies in Southern Africa. Research efforts made to evaluate threats and opportunities of indigenous beef cattle production systems, assess the contribution of indigenous cattle to household food security and income, genetically and phenotypically characterize and conserve indigenous breeds, and develop breeding programs for smallholder beef production are highlighted. Although smallholder beef cattle production in the smallholder farming systems contributes substantially to household food security and income, their productivity is hindered by several constraints that include high prevalence of diseases and parasites, limited feed availability and poor marketing. The majority of the African cattle populations remain largely uncharacterized although most of the indigenous cattle breeds have been identified. PMID:27004814

  1. Fossils and fire: a study on the effects of fire on paleontological resources at Badlands National Park

    Treesearch

    Rachel Benton; James Reardon

    2006-01-01

    National Park Service policies stipulate that each park with vegetation capable of burning will prepare a fire management plan. Badlands National Park completed its fire management plan in 2004. Fossils are a principle resource of the park and the fire sensitivity of fossils is the focus of this study. The surface temperatures of fossil specimens and fire behavior...

  2. 77 FR 59662 - National Park Service Alaska Region's Subsistence Resource Commission Program; Open Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ... Subsistence Resource Commission (SRC) will meet to develop and continue work on National Park Service (NPS... upon request from the park superintendent for public inspection approximately six weeks after each.../teleconference will be held on Monday, October 1, 2012, from 1:30 p.m. to 4 p.m. or until business is completed...

  3. National water resource management as a global problem: The example of Egypt

    NASA Astrophysics Data System (ADS)

    Elshorbagy, A. A.; Abdelkader, A. A.; Tuninetti, M.; Laio, F.; Ridolfi, L.; Fahmy, H.

    2017-12-01

    The engineering redistribution of water remains limited in its spatial scope, when compared with the socioeconomic redistribution of water in its virtual form. Virtual water (VW) embedded in products has its own human-induced cycle by moving across the globe. There is a significant body of literature on global VW trade networks (VWTN), with most studies focused on the network structure and the variables controlling its behavior. It was shown that the importing nations will play an important role in the evolution of the network dynamics. The increased connectivity of the global network highlights the risk of systemic disruptions and the vulnerability of the global food, especially when exporting countries change to non-exporting ones. The existing models of VWTN characterize the properties of the network, along with its nodes and links. Acknowledging its contribution to understand the global redistribution of virtual water, hardly can this approach attract potential users to adopt it. The VW trade (VWT) modeling needs to be repositioned to allow resource managers and policy makers at various scales to benefit from it and link global VW dynamics to their local decisions. The aim of this research is to introduce a new modeling approach for the VWT where detailed national scale water management is nested within the coarser global VWTN. The case study of Egypt, the world biggest importer of wheat, is considered here because its population growth and limitations of water and arable land position it as a significant node in the global network. A set of potential scenarios of Egypt's future, driven by population growth, development plans, consumption patterns, technology change, and water availability are developed. The annual national food and water balance in every scenario is calculated to estimate the potential for VW export and import of Egypt. The results indicate that Egypt's demand for food might cause unexpectedly higher demands on other countries' water resources

  4. National aerial photography program as a geographic information system resource

    USGS Publications Warehouse

    Light, Donald L.

    1991-01-01

    The National Aerial Photography Program (NAPP) is jointly funded by Federal agencies and States that choose to participate in a 50-50 cost sharing cooperative arrangement. The NAPP is designed to acquire black-and-white (B&W) or color infrared (CIR) photography at a scale of 1:40,000. The status of NAPP flying, now going into the first year of its second 5-year cycle, is reviewed to inform the user community of NAPP's coverage. The resolution, geometric quality and flight parameters are used to estimate the system's cartographic potential to produce orthophotoquads, digital elevation models, topographic maps and digital information to meet national map accuracy standards at 1:12,000 and 1:24,000-scale and serve as a geographic information system resource. Also, a technique is presented to compute the optimum scanning spot size (15 ??m) and storage required for converting the B&W or CIR photography to digital, machine-readable pixel form. The resulting digital NAPP data are suitable for a wide variety of new applications, including use in geographic information systems.

  5. The United Nations framework classification for fossil energy and mineral reserves and resources 2009

    USGS Publications Warehouse

    MacDonald, D.; Lynch-Bell, M.; Ross, J.; Heiberg, S.; Griffiths, C.; Klett, T.

    2011-01-01

    Effective resource management in a globalizing economy requires accurate assessments of fossil energy and minerals resources. The recoverable quantities must be described and categorized in a manner that is consistent with scientific and social/economic information describing the economy as well as with the information describing the projects to recover them. A number of different standards have evolved over time in response to various professional needs Under a mandate given by the United Nations Economic and Social Council, the United Nations Economic Commission for Europe (UNECE) has cooperated with Governments, regulatory agencies, industry, international organizations, and professional organizations (including Committee for Mineral Reserves International Reporting Standards (CRIRSCO), the Society of Petroleum Engineers (SPE), the American Association of Petroleum Geologists (AAPG), and the Society of Petroleum Evaluation Engineers (SPEE)), as well as with outstanding experts, to define a global classification for extractive activities (including oil, gas, heavy oil and bitumen extraction) that reflects the principal concerns of existing petroleum and mineral classifications. The United Nations Framework Classification for Fossil Energy and Mineral Reserves and Resources-2009 (UNFC-2009) aims to serve the following four principal needs: 1. The needs in international energy and mineral studies to formulate robust and long-sighted policies. 2. The needs of governments in managing their resources accordingly, allowing market prices to be transferred to the wellhead with as little loss as possible. 3. The industries' needs for information while deploying technology, management and finance to secure energy supplies and capture value efficiently within the established frameworks to serve its host countries, shareholders and stakeholders. 4. The financial community's need for information to allocate capital appropriately, providing reduced costs and improved long

  6. Geospatial resources for the geologic community: The USGS National Map

    USGS Publications Warehouse

    Witt, Emitt C.

    2015-01-01

    Geospatial data are a key component of investigating, interpreting, and communicating the geological sciences. Locating geospatial data can be time-consuming, which detracts from time spent on a study because these data are not obviously placed in central locations or are served from many disparate databases. The National Map of the US Geological Survey is a publicly available resource for accessing the geospatial base map data needs of the geological community from a central location. The National Map data are available through a viewer and download platform providing access to eight primary data themes, plus the US Topo and scanned historical topographic maps. The eight themes are elevation, orthoimagery, hydrography, geographic names, boundaries, transportation, structures, and land cover, and they are being offered for download as predefined tiles in formats supported by leading geographic information system software. Data tiles are periodically refreshed to capture the most current content and are an efficient method for disseminating and receiving geospatial information. Elevation data, for example, are offered as a download from the National Map as 1° × 1° tiles for the 10- and 30- m products and as 15′ × 15′ tiles for the higher-resolution 3-m product. Vector data sets with smaller file sizes are offered at several tile sizes and formats. Partial tiles are not a download option—any prestaged data that intersect the requesting bounding box will be, in their entirety, part of the download order. While there are many options for accessing geospatial data via the Web, the National Map represents authoritative sources of data that are documented and can be referenced for citation and inclusion in scientific publications. Therefore, National Map products and services should be part of a geologist’s first stop for geospatial information and data.

  7. A cross-sectional ecological analysis of international and sub-national health inequalities in commercial geospatial resource availability.

    PubMed

    Dotse-Gborgbortsi, Winfred; Wardrop, Nicola; Adewole, Ademola; Thomas, Mair L H; Wright, Jim

    2018-05-23

    Commercial geospatial data resources are frequently used to understand healthcare utilisation. Although there is widespread evidence of a digital divide for other digital resources and infra-structure, it is unclear how commercial geospatial data resources are distributed relative to health need. To examine the distribution of commercial geospatial data resources relative to health needs, we assembled coverage and quality metrics for commercial geocoding, neighbourhood characterisation, and travel time calculation resources for 183 countries. We developed a country-level, composite index of commercial geospatial data quality/availability and examined its distribution relative to age-standardised all-cause and cause specific (for three main causes of death) mortality using two inequality metrics, the slope index of inequality and relative concentration index. In two sub-national case studies, we also examined geocoding success rates versus area deprivation by district in Eastern Region, Ghana and Lagos State, Nigeria. Internationally, commercial geospatial data resources were inversely related to all-cause mortality. This relationship was more pronounced when examining mortality due to communicable diseases. Commercial geospatial data resources for calculating patient travel times were more equitably distributed relative to health need than resources for characterising neighbourhoods or geocoding patient addresses. Countries such as South Africa have comparatively high commercial geospatial data availability despite high mortality, whilst countries such as South Korea have comparatively low data availability and low mortality. Sub-nationally, evidence was mixed as to whether geocoding success was lowest in more deprived districts. To our knowledge, this is the first global analysis of commercial geospatial data resources in relation to health outcomes. In countries such as South Africa where there is high mortality but also comparatively rich commercial geospatial

  8. Engaging First Nation and Inuit communities in asthma management and control: assessing cultural appropriateness of educational resources.

    PubMed

    Latycheva, O; Chera, R; Hampson, C; Masuda, J R; Stewart, M; Elliott, S J; Fenton, N E

    2013-01-01

    Asthma is a growing concern in First Nations and Inuit communities. As with many health indicators and outcomes, Aboriginal peoples living in remote areas experience greater disparities in respiratory health compared with non-Aboriginal Canadians. Therefore, it is critically important to take into account their unique needs when developing asthma educational materials and resources. The purpose of this study is to assess the cultural relevance of existing asthma education materials for First Nations and Inuit peoples. Five First Nations and Inuit communities from across Canada participated in the project. A combination of quantitative evaluations (eg surveys) and qualitative approaches (eg open discussion, live chats) were used to assess printed and web-based asthma education materials. Participants represented First Nations and Inuit communities from across Canada and were selected on the basis of age and role: 6 to 12 years old (children), 12 and over (youth), parents and grandparents, community leaders and teachers, and community advisory group members. In general, the results showed that although participants of all age categories liked the selection of asthma educational materials and resources, they identified pictures and images related to First Nations and Inuit people living and coping with asthma as ways of improving cultural relevance. This reinforces findings that tailoring materials to include Aboriginal languages, ceremonies and traditions would enhance their uptake. Our findings also demonstrate that visually based content in both printed and virtual form were the preferred style of learning of all participants, except young children who preferred to learn through play and interactive activities. Asthma is a growing concern in First Nations and Inuit communities. Given this concern, it is essential to understand cultural needs and preferences when developing asthma education materials and resources. The findings from this research emphasize the need

  9. Multinational corporations, nation-states and ocean resource management: the impact of the world's 200-mile economic zone on multinational and national development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gopalakrishnan, C.

    1979-07-01

    The extension of coastal state jurisdiction to 200-nautical miles - a fact of international law about to receive juridical status - would lead to a unique situation in the ownership of ocean resources, viz. 15 coastal states would receive among them approximately 42% of the world's 200-mile economic zone area. At least 8 of these countries are less-developed coastal states (LDCS) which lack the key factors, capital, technology, and managerial skill, necessary to tap these resources. As a result, the reliance of the LDCS on marine multinational corporations will markedly increase since a significant part of marine technology exists inmore » the private sector. Concurrently, a dramatic rise in the control of coastal states over MNCs engaged in ocean resource development will occur. Thus, under the new regime of ocean resource management, the relationship between MNCs and nation-states is likely to be one of constructive partnership in development, rather than one of conflict and discord.« less

  10. 77 FR 42758 - Notice of Availability of the Prehistoric Trackways National Monument Draft Resource Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-20

    ... Environmental Impact Statement, New Mexico AGENCY: Bureau of Land Management, Interior. ACTION: Notice of availability. SUMMARY: In accordance with the National Environmental Policy Act of 1969, as amended, and the... prepared a Draft Resource Management Plan (RMP) and Draft Environmental Impact Statement (EIS) for the...

  11. Genetic moderation of multiple pathways linking early cumulative socioeconomic adversity and young adults' cardiometabolic disease risk.

    PubMed

    Wickrama, Kandauda A S; Lee, Tae Kyoung; O'Neal, Catherine Walker

    2018-02-01

    Recent research suggests that psychosocial resources and life stressors are mediating pathways explaining socioeconomic variation in young adults' health risks. However, less research has examined both these pathways simultaneously and their genetic moderation. A nationally representative sample of 11,030 respondents with prospective data collected over 13 years from the National Study of Adolescent to Adult Health was examined. First, the association between early cumulative socioeconomic adversity and young adults' (ages 25-34) cardiometabolic disease risk, as measured by 10 biomarkers, through psychosocial resources (educational attainment) and life stressors (accelerated transition to adulthood) was examined. Second, moderation of these pathways by the serotonin transporter linked polymorphic region gene (5-HTTLPR) was examined. There was evidence for the association between early socioeconomic adversity and young adults' cardiometabolic disease risk directly and indirectly through educational attainment and accelerated transitions. These direct and mediating pathways were amplified by the 5-HTTLPR polymorphism. These findings elucidate how early adversity can have an enduring influence on young adults' cardiometabolic disease risk directly and indirectly through psychosocial resources and life stressors and their genetic moderation. This information suggests that effective intervention and prevention programs should focus on early adversity, youth educational attainment, and their transition to young adulthood.

  12. Human Ageing Genomic Resources: Integrated databases and tools for the biology and genetics of ageing

    PubMed Central

    Tacutu, Robi; Craig, Thomas; Budovsky, Arie; Wuttke, Daniel; Lehmann, Gilad; Taranukha, Dmitri; Costa, Joana; Fraifeld, Vadim E.; de Magalhães, João Pedro

    2013-01-01

    The Human Ageing Genomic Resources (HAGR, http://genomics.senescence.info) is a freely available online collection of research databases and tools for the biology and genetics of ageing. HAGR features now several databases with high-quality manually curated data: (i) GenAge, a database of genes associated with ageing in humans and model organisms; (ii) AnAge, an extensive collection of longevity records and complementary traits for >4000 vertebrate species; and (iii) GenDR, a newly incorporated database, containing both gene mutations that interfere with dietary restriction-mediated lifespan extension and consistent gene expression changes induced by dietary restriction. Since its creation about 10 years ago, major efforts have been undertaken to maintain the quality of data in HAGR, while further continuing to develop, improve and extend it. This article briefly describes the content of HAGR and details the major updates since its previous publications, in terms of both structure and content. The completely redesigned interface, more intuitive and more integrative of HAGR resources, is also presented. Altogether, we hope that through its improvements, the current version of HAGR will continue to provide users with the most comprehensive and accessible resources available today in the field of biogerontology. PMID:23193293

  13. The National Resource Library for Science and Technology in Sweden: A Nordic model of cooperating technology libraries

    NASA Technical Reports Server (NTRS)

    Lagar, Gunnar

    1994-01-01

    The scope of this presentation is to give a state-of-the-art report on the present situation of Nordic technology libraries, to elaborate on a plan for national resource libraries in Sweden, and to share how the Royal Institute of Technology Library in Stockholm (KTHB) has fostered a network of cooperating libraries in order to optimize government funding for the system of resource libraries.

  14. Good genes – using germplasm and breeding to create new plants at the U.S. National Arboretum

    USDA-ARS?s Scientific Manuscript database

    The U.S. National Arboretum was established in 1927 and occupies 446 acres in Northeast Washington, D.C. Its mission is to enhance the economic, environmental, and aesthetic value of ornamental and landscape plants through long-term, multi-disciplinary research, conservation of genetic resources, an...

  15. The Pakistan Risk of Myocardial Infarction Study: a resource for the study of genetic, lifestyle and other determinants of myocardial infarction in South Asia

    PubMed Central

    2009-01-01

    The burden of coronary heart disease (CHD) is increasing at a greater rate in South Asia than in any other region globally, but there is little direct evidence about its determinants. The Pakistan Risk of Myocardial Infarction Study (PROMIS) is an epidemiological resource to enable reliable study of genetic, lifestyle and other determinants of CHD in South Asia. By March 2009, PROMIS had recruited over 5,000 cases of first-ever confirmed acute myocardial infarction (MI) and over 5,000 matched controls aged 30–80 years. For each participant, information has been recorded on demographic factors, lifestyle, medical and family history, anthropometry, and a 12-lead electrocardiogram. A range of biological samples has been collected and stored, including DNA, plasma, serum and whole blood. During its next stage, the study aims to expand recruitment to achieve a total of about 20,000 cases and about 20,000 controls, and, in subsets of participants, to enrich the resource by collection of monocytes, establishment of lymphoblastoid cell lines, and by resurveying participants. Measurements in progress include profiling of candidate biochemical factors, assay of 45,000 variants in 2,100 candidate genes, and a genomewide association scan of over 650,000 genetic markers. We have established a large epidemiological resource for CHD in South Asia. In parallel with its further expansion and enrichment, the PROMIS resource will be systematically harvested to help identify and evaluate genetic and other determinants of MI in South Asia. Findings from this study should advance scientific understanding and inform regionally appropriate disease prevention and control strategies. PMID:19404752

  16. The North American Forest Database: going beyond national-level forest resource assessment statistics.

    PubMed

    Smith, W Brad; Cuenca Lara, Rubí Angélica; Delgado Caballero, Carina Edith; Godínez Valdivia, Carlos Isaías; Kapron, Joseph S; Leyva Reyes, Juan Carlos; Meneses Tovar, Carmen Lourdes; Miles, Patrick D; Oswalt, Sonja N; Ramírez Salgado, Mayra; Song, Xilong Alex; Stinson, Graham; Villela Gaytán, Sergio Armando

    2018-05-21

    Forests cannot be managed sustainably without reliable data to inform decisions. National Forest Inventories (NFI) tend to report national statistics, with sub-national stratification based on domestic ecological classification systems. It is becoming increasingly important to be able to report statistics on ecosystems that span international borders, as global change and globalization expand stakeholders' spheres of concern. The state of a transnational ecosystem can only be properly assessed by examining the entire ecosystem. In global forest resource assessments, it may be useful to break national statistics down by ecosystem, especially for large countries. The Inventory and Monitoring Working Group (IMWG) of the North American Forest Commission (NAFC) has begun developing a harmonized North American Forest Database (NAFD) for managing forest inventory data, enabling consistent, continental-scale forest assessment supporting ecosystem-level reporting and relational queries. The first iteration of the database contains data describing 1.9 billion ha, including 677.5 million ha of forest. Data harmonization is made challenging by the existence of definitions and methodologies tailored to suit national circumstances, emerging from each country's professional forestry development. This paper reports the methods used to synchronize three national forest inventories, starting with a small suite of variables and attributes.

  17. International Conference of Directors of National Libraries on Resource Sharing in Asia and Oceanic [Proceedings] (Canberra, Australia, May 14-18, 1979). Development of Resource Sharing Networks. Networks Study No. 11.

    ERIC Educational Resources Information Center

    National Library of Australia, Canberra.

    The proceedings of this 1979 conference on library cooperation begin with proposals for the promotion of resource sharing among the national libraries of Asia and Oceania, the text of a policy statement on the role of national and international systems as approved at a 1976 meeting of directors of national libraries held in Lausanne, and a summary…

  18. Identification of Strategies to Leverage Public and Private Resources for National Security Workforce Development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2009-02-01

    This report documents the identification of strategies to leverage public and private resources for the development of an adequate national security workforce as part of the National Security Preparedness Project (NSPP).There are numerous efforts across the United States to develop a properly skilled and trained national security workforce. Some of these efforts are the result of the leveraging of public and private dollars. As budget dollars decrease and the demand for a properly skilled and trained national security workforce increases, it will become even more important to leverage every education and training dollar. The leveraging of dollars serves many purposes.more » These include increasing the amount of training that can be delivered and therefore increasing the number of people reached, increasing the number and quality of public/private partnerships, and increasing the number of businesses that are involved in the training of their future workforce.« less

  19. Standards in Action. Using National Standards for Human Resource Management and Development in Further Education. 1. Laying the Foundations.

    ERIC Educational Resources Information Center

    Further Education Unit, London (England).

    This booklet is designed to assist British further education college managers responsible for quality assurance, human resources management (HRM), human resources development (HRD), corporate development, strategic planning, staffing/personnel, and curriculum in using national standards for HRM and HRD in further education. A synopsis, users'…

  20. Genetics Home Reference: Paget disease of bone

    MedlinePlus

    ... genetic cause of classic Paget disease of bone , accounting for 10 to 50 percent of cases that ... be inherited? More about Inheriting Genetic Conditions Diagnosis & Management Resources Genetic Testing (6 links) Genetic Testing Registry: ...