Science.gov

Sample records for naturales por las

  1. Las ideologias, las ciencias naturales y sus implicaciones en la educacion cientifica

    NASA Astrophysics Data System (ADS)

    Lozada Roldan, Sandra

    acerca de las ideologias, a la luz de la literatura consultada. Entre estas concepciones se destacan las siguientes: a) la funcion de las ideologias y b) la ausencia de validez ante el conocimiento cientifico. Sin embargo, en cuanto a considerar las ciencias naturales como una ideologia mas conocida como cientificismo, no hubo consistencia en las respuestas de los participantes por lo que no es posible afirmarlo o negarlo. Los hallazgos tambien revelaron que entre los docentes participantes hubo posiciones a favor y en contra para las dos situaciones sobre asuntos publicos relacionados a la ciencia que se presentaron. Estas posiciones fueron justificadas con argumentos cientificos y argumentos ideologicos, entre estos, los morales y los economicos. Con este dato se puede afirmar el uso de las ideologias en asuntos publicos relacionados a la ciencia.

  2. Conceptuaciones de los estudiantes de las facultades de educacion y ciencias naturales de la Universidad de Puerto Rico, recinto de Rio Piedras, acerca de la ciencia y la pseudociencia

    NASA Astrophysics Data System (ADS)

    Reyes Medina, Hector A.

    Esta investigacion describe las conceptuaciones de los estudiantes de tercer ano o mas a nivel de bachillerato de los programas de Educacion en Ciencia y Ciencias Naturales de la Universidad de Puerto Rico, Recinto de Rio Piedras, acerca de lo establecido en la literatura para distinguir el conocimiento cientifico de las creencias pseudocientificas. Este estudio se guio por un diseno tipo encuesta transversal que permitio conocer de manera consistente las conceptuaciones de los estudiantes encuestados acerca de la Ciencia y la Pseudociencia. Ademas, permitio desarrollar inferencias estadisticas relacionadas a la poblacion de estudio, sus conceptuaciones y su inclinacion teorica en torno al Realismo y al Racionalismo cientifico moderados. El instrumento utilizado fue el Cuestionario acerca de las concepciones de la ciencia y la pseudocienca en estudiantes universitarios, Reyes (2015). Este cuestionario fue validado mediante la recopilacion de diversas fuentes de evidencias, entre estas se encuentran las evidencias basadas en el contenido, el proceso de respuesta, la estructura interna y de constructo. Tambien, se calculo el Alfa de Crombach para la escala total y para cada componente y se realizo un analisis de factores que demostro la presencia de seis componentes claramente definidos de acuerdo a lo esperado sobre las caracteristicas originales del instrumento. Las estadisticas utilizadas fueron descriptivas. Participaron 302 alumnos, de las facultades de educacion y ciencias naturales. Se encontro que las conceptuaciones de los estudiantes de ambas facultades se inclinan en un 66.2% a favor con lo establecido en el modelo teorico en torno al Realismo y al Racionalismo cientifico moderados. Sin embargo, aun hay un 33.8% de los estudiantes de ambas facultades que poseen conceptuaciones distintas al modelo teorico propuesto.

  3. Disminuyen en los Estados Unidos las infecciones por VPH.

    Cancer.gov

    La infección por los tipos del virus del papiloma humano (VPH) en el blanco de la vacuna cuadrivalente se redujo en casi dos tercios en las adolescentes desde que se recomendó la vacunación en los Estados Unidos.

  4. Preparación de los adultos mayores en los Estados Unidos para hacer frente a los desastres naturales: encuesta a escala nacional*

    PubMed Central

    Al-rousan, Tala M.; Rubenstein, Linda M.; Wallace, Robert B.

    2015-01-01

    Objetivos. Nos propusimos determinar el grado de preparación frente a los desastres naturales de los adultos mayores en los Estados Unidos y evaluar los factores que pueden afectar negativamente la salud y la seguridad durante este tipo de incidentes. Métodos. Obtuvimos una muestra de adultos de 50 años en adelante (n = 1 304) de la encuesta del 2010 del Estudio de la Salud y la Jubilación (HRS por su sigla en inglés). La encuesta recogió datos sobre las características demográficas generales, el estado de discapacidad o las limitaciones funcionales, y también sobre factores y comportamientos relacionados con la preparación frente a los desastres. Calculamos una puntuación global de preparación mediante indicadores individuales a fin de evaluar el grado de preparación general. Resultados. La media de la edad de los participantes (n = 1 304) fue de 70 años (desviación estándar [DE] = 9,3). Solo 34,3% informaron que habían participado en un programa formativo o que habían leído materiales sobre la preparación para los desastres. Casi 15% indicaron que usaban dispositivos médicos eléctricos que podían correr riesgo de no funcionar si se interrumpiera el suministro eléctrico. La puntuación de preparación indicó que la edad más avanzada, la discapacidad física y el menor nivel de escolaridad y de ingresos se asociaban independiente y significativamente a un grado de preparación general inferior. Conclusiones. A pesar de la mayor vulnerabilidad ante los desastres y del número cada vez mayor de adultos mayores en los Estados Unidos, muchos de los problemas sustanciales que encontramos son remediables y requieren atención en los sectores de la sociedad dedicados a la atención clínica, a la salud pública y al manejo de situaciones de emergencia.

  5. El origen de las galaxias en modelos jerárquicos de formación de la estructura

    NASA Astrophysics Data System (ADS)

    Navarro, J. F.

    En esta charla presentaré una revisión de los modelos corrientes de formación de galaxias. En particular, haré énfasis en el origen de la gran variedad de morfologías galácticas y de las correlaciones entre las propiedades estructurales de discos y esferoides, todo dentro del contexto cosmológico jerárquico provisto por teorías como la de materia oscura fría. En este tipo de teorías las correlaciones observadas entre la luminosidad, velocidad de rotación, momento angular, y tamaño de galaxias son el resultado de la falta de escalas naturales en el proceso de formación de los halos de materia oscura que dichas galaxias habitan. Simulaciones numéricas que incorporan efectos gravitacionales, hidrodinámicos y de formación estelar ilustran estas ideas y demuestran las dificultades que aquejan a modelos donde tanto discos como esferoides son el resultado final de una secuencia de fusiones de sistemas protogalácticos.

  6. Eficacia de la detección sistemática de la gripe en las fronteras en los viajeros que llegan por vía aérea*

    PubMed Central

    Priest, Patricia C.; Jennings, Lance C.; Duncan, Alasdair R.; Brunton, Cheryl R.; Baker, Michael G.

    2015-01-01

    Objetivos. Se midieron los síntomas y la prevalencia de la gripe (también llamada influenza), así como la eficacia del mecanismo de detección sistemática basado en los síntomas y la temperatura para diagnosticar la gripe en viajeros internacionales que llegaban por vía aérea. Métodos. El presente estudio transversal recopiló datos de viajeros que llegaron al aeropuerto internacional de Christchurch (Nueva Zelandia) en el invierno del 2008 mediante un cuestionario de salud, medición de la temperatura y toma de muestras de las vías respiratorias. Resultados. De los viajeros, 15 976 (68%) entregaron los formularios completos. De ellos, 17% notificaron al menos un síntoma de gripe; los síntomas más comunes fueron rinorrea o congestión nasal (10%) y tos (8%). Se tomaron muestras de las vías respiratorias de 3 769 viajeros. La prevalencia estimada de la gripe fue de 1,1% (4% en las personas sintomáticas, 0,2% en las asintomáticas). La sensibilidad de los criterios de detección varió de 84% para “cualquier síntoma” a 3% para la fiebre de 37,8 °C o mayor. El valor predictivo positivo fue bajo para todos los criterios. Conclusiones. El método de detección sistemática en las fronteras mediante la autonotificación de síntomas y la toma de la temperatura presenta limitaciones para impedir que una gripe pandémica entre en un país. Basarse en criterios como “cualquier síntoma” o la tos haría que se investigara a varias personas no infectadas, mientras que algunas personas infectadas pasarían inadvertidas. Si se usaran criterios más específicos como la fiebre, la mayoría de las personas infectadas entrarían en el país a pesar del mecanismo de detección.

  7. Salud mental en desastres naturales: estrategias interventivas con adultos mayores en sectores rurales de Chile.

    PubMed

    Osorio-Parraguez, Paulina; Espinoza, Adriana

    2016-06-01

    En el presente artículo se da a conocer una estrategia de intervención llevada a cabo con adultos mayores en la comuna de Paredones, sexta región de Chile, con posterioridad al terremoto y tsunami del 27 de febrero 2010 en Chile, en el contexto de una investigación sobre fortalezas y vulnerabilidades desplegadas por este grupo etario, con posterioridad a un desastre natural. Se presenta una descripción del desarrollo metodológico de la intervención y de los sustentos teóricos y conceptuales en los que se basa. Como resultado de este proceso, se propone una estrategia que trabaje a través de la identificación de las propias experiencias y fortalezas de los sujetos. De tal forma se minimizan los efectos negativos de los determinantes sociales de la salud (como la edad y el lugar de residencia) en contexto de crisis; permitiendo a los adultos mayores fortalecer sus recursos individuales y colectivos, en pro de su bienestar psicosocial. PMID:25724751

  8. An Example of Health Education in the Early 17th Century: "Naturall and Artificial Directions for Health" by William Vaughan

    ERIC Educational Resources Information Center

    Charlton, Anne

    2005-01-01

    In 1600, William Vaughan, a Doctor of Civil Laws, published the first edition of his health education manual entitled "Naturall and artificial Directions for Health". In all, seven editions appeared over the next 33 years. Changes were made to the title and contents, but the same six general areas were covered in each, i.e. (1) Air, fire and…

  9. Las Vegas

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This image of Las Vegas, NV was acquired on August, 2000 and covers an area 42 km (25 miles) wide and 30 km (18 miles) long. The image displays three bands of the reflected visible and infrared wavelength region, with a spatial resolution of 15 m. McCarran International Airport to the south and Nellis Air Force Base to the NE are the two major airports visible. Golf courses appear as bright red areas of worms. The first settlement in Las Vegas (which is Spanish for The Meadows) was recorded back in the early 1850s when the Mormon church, headed by Brigham Young, sent a mission of 30 men to construct a fort and teach agriculture to the Indians. Las Vegas became a city in 1905 when the railroad announced this city was to be a major division point. Prior to legalized gambling in 1931, Las Vegas was developing as an agricultural area. Las Vegas' fame as a resort area became prominent after World War II. The image is located at 36.1 degrees north latitude and 115.1 degrees west longitude.

    The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

  10. Desigualdades por cáncer

    Cancer.gov

    Información básica de las desigualdades en salud por cáncer en EE. UU., factores que contribuyen a la carga desproporcionada del cáncer en algunos grupos y ejemplos de desigualdades en incidencia y mortalidad entre ciertos grupos de la población.

  11. Proving the Orbits of the Galilean Moons Through Astrophotography. (Spanish Title: Comprobando Las Órbitas de Las Lunas Galileanas a Través de la Astrofotografía.) Evidenciando as Órbitas das Luas Galileanas Atravéd da Astrofotografia

    NASA Astrophysics Data System (ADS)

    Iachel, Gustavo

    2009-12-01

    An activity related to the observation of the Galilean moons and to amateur astrophotography is presented in this work. Through the reading of excerpts of the book Sidereus Nuncius (Sidereal Messenger), by Galileo, it is possible to trace a methodology to observe the planet and its natural satellites and, with the aid of the astrophotography, to analyze the field recordings. Moreover, it is possible to compare the images obtained after plotting the relative positions of these moons to prove their orbits. This activity can be conducted by teachers, students and amateur astronomers, in order to develop their capabilities of observation of astronomical phenomena. Se presenta en este trabajo una actividad relacionada a la observación de las lunas Galileanas y a la astrofotografía amateur. A través de la lectura de tramos de la obra Sidereus Nuncius (El Mensajero Sideral) de Galileo, es posible trazar una metodología para la observación del planeta y de sus satélites naturales y, con el auxilio de la astrofotografía, analizar las anotaciones de campo. Además, es posible comparar las imágenes obtenidas con el gráfico de las posiciones relativas de estas lunas para comprobar sus órbitas. Esa actividad puede ser realizada por maestros, estudiantes y astrónomos amateurs, de forma a desarrollar sus capacidades de observación de los fenómenos astronómicos. Uma atividade relacionada à observação das luas Galileanas e à astrofotografia amadora é apresentada neste trabalho. Através da leitura de trechos da obra Sidereus Nuncius (Mensageiro Sideral), de Galileu, é possível traçar uma metodologia para a observação do planeta e de seus satélites naturais e, com o auxílio da astrofotografia, analisar as anotações de campo. Além disso, é possível comparar as imagens obtidas com o gráfico das posições relativas destas luas para evidenciar suas órbitas. Essa atividade pode ser realizada por professores, estudantes e astrônomos amadores, de forma a

  12. Astronomy in the Classroom: Why? (Spanish Title: Astronomía en la Clase: ¿Por Qué?) Astronomia na Sala de Aula: Por Quê?

    NASA Astrophysics Data System (ADS)

    Daros Gama, Leandro; Bagdonas Henrique, Alexandre

    2010-07-01

    There are many discussions about the relevance of the topics covered in classes. One subject in particular is the focus of this essay: astronomy. In what sense and to what extent it would be worth to teach it in science or other kind of classes? In this paper we discuss some aspects of the advantages of dealing with this area of knowledge in schools, taking into account the epistemological and axiological dimensions of astronomy, in light of the vision of science as an intelligent dialogue with the world (Bachelard), in addition to the "problematization" knowledge of Paulo Freire. We propose that in fact the Astronomy does not need to be seen as just a new set of contents to be taught, but appears as a set of motivational contents for historical-philosophical discussions, and permit the discussion of concepts of other disciplines. Numerosas discusiones se están llevando a cabo acerca de la pertinencia de los temas tradicionalmente tratados en las clases. Uno de los temas, en particular, es el foco de este ensayo: la astronomía. ¿En qué sentido y en qué medida sería conveniente tratarla en clase, ya sea en clases de ciencias naturales, específicamente en las de astronomía o asignaturas afines? Elaboramos en este artículo algunos aspectos de las ventajas de tratar esta área del conocimiento en las escuelas, teniendo en cuenta las dimensiones epistemológica y axiológica de la astronomía, a la luz de la visión de la ciencia como un diálogo inteligente con el mundo (Bachelard), además de la propuesta del conocimiento "problematizador" de Paulo Freire. Proponemos que en realidad la astronomía no tiene por qué ser vista sólo como un nuevo conjunto de contenidos que se enseñan, sino que aparece como un conjunto de temas de motivación para el debate histórico-filosófico y para permitir la discusión de los conceptos típicos de otras disciplinas. Muitas discussões vêm acontecendo sobre a relevância dos temas abordados em sala de aula. Um tema, em

  13. ?Cuales son las amenazas o peligros volcanicos?

    USGS Publications Warehouse

    Myers, Bobbie; Brantley, Steven R.; Stauffer, Peter; Hendley, James W., II

    2000-01-01

    Los volcanes son capaces de producir numerosos peligros geologicos e hidrologicos. Los cientificos del Servicio Geologico de los EE. UU. (USGS, por sus siglas en ingles) y de otras instituciones alrededor del mundo estan estudiando los peligros de muchos de los centenares de volcanes activos y potencialmente activos del mundo. Estos cientificos vigilan muy de cerca la actividad de algunos de los volcanes mas peligrosos, por lo que estan preparados para alertar a las autoridades y/o a la poblacion en caso de que aumente sustancialmente la probabilidad de que ocurra una erupcion u otro evento peligroso.

  14. La edad de las familias Eos, Themis y Koronis

    NASA Astrophysics Data System (ADS)

    Gil-Hutton, R.

    Las familias de asteroides son el producto de la disrupción colisional de objetos destruídos por impactos ocurridos en el cinturón principal. Las colisiones posteriores han modificado los tamaños y las órbitas de los miembros de estas familias, por lo que las distribuciones que vemos hoy en día pueden ser muy diferentes de aquellas producidas inmediatamente después de la fragmentación del objeto original. En esta hipótesis, puede ser difícil reconstruir la evolución colisional de la familia basándose sólo en las actuales distribuciones y puede ser necesario hacer ciertas suposiciones para obtener información sobre las condiciones iniciales. En este trabajo se deriva una estimación de la edad de las familias Eos, Themis y Koronis obtenida de una simulación de la evolución colisional de un cuerpo original teórico para cada familia usando un modelo de distribución para el cinturón propuesto por Gil-Hutton (1996).

  15. Portable exhausters POR-004 SKID B, POR-005 SKID C, POR-006 SKID D storage plan

    SciTech Connect

    Nelson, O.D.

    1997-09-04

    This document provides a storage plan for portable exhausters POR-004 SKID B, POR-005 SKID C, AND POR-006 SKID D. The exhausters will be stored until they are needed by the TWRS (Tank Waste Remediation Systems) Saltwell Pumping Program. The storage plan provides criteria for portable exhauster storage, periodic inspections during storage, and retrieval from storage.

  16. Variación temporal de las constantes fundamentales

    NASA Astrophysics Data System (ADS)

    Landau, S. J.; Vucetich, H.

    La variación temporal de las constantes fundamentales es un problema que ha motivado numerosos trabajos teóricos y experimentales desde la hipótesis de los grandes números de Dirac en 1937. Entre los métodos experimentales y observacionales para establecer restricciones sobre la variación de las constantes fundamentes es importante mencionar: comparación entre relojes atómicos[1], métodos geofísicos[2][3], análisis de sistemas de absorción en quasares[4][5][6] y cotas provenientes de la nucleosíntesis primordial[7]. En un trabajo reciente[5], se reportó una significativa variación en la constante de estructura fina. Intentos de unificar las cuatro interacciones fundamentales dieron como resultado teorías con múltiples dimensiones como las teorías de Kaluza-Klein y teorías de supercuerdas. Estas teorías proporcionan un marco teórico natural para el estudio de la variación temporal de las constantes fundamentales. A su vez, un modelo sencillo para estudiar la variación de la constante de estructura fina, fue propuesto en [8], a partir de premisas muy generales como ser covarianza, invarianza de gauge, causalidad y invarianza ante reversiones temporales en el electromagnetismo. Diferentes versiones de las teorías antes mencionadas coinciden en predecir variaciones temporales de las constantes fundamentales pero difieren en la forma de esta variación[9][10]. De esta manera, las restricciones establecidas experimentalmente sobre la variación de las constantes fundamentales pueden ser una herramienta importante para testear estas diferentes teorías. En este trabajo, utilizamos las cotas provenientes de diversas técnicas experimentales, para testear si las mismas son consistentes con alguna de las teorías antes mencionadas. En particular, establecemos cotas sobre la variación de los parámentros libres de las diferentes teorías como por ejemplo el radio de las dimensiones extras en las teorías tipo Kaluza-Klein.

  17. Land Analysis System (LAS)

    NASA Technical Reports Server (NTRS)

    Pease, P. B.

    1989-01-01

    Version 4.1 of LAS provides flexible framework for algorithm development and processing and analysis of image data. Over 500,000 lines of code enable image repair, clustering, classification, film processing, geometric registration, radiometric correction, and manipulation of image statistics.

  18. Revision curricular a partir de un analisis comparativo de las discrepancias en los curriculos de una escuela de optometria en Puerto Rico con las competencias requeridas para las agencias de revalida y acreditacion 2004

    NASA Astrophysics Data System (ADS)

    Rivera Pacheco, Andres

    El proposito de esta investigacion, un estudio cualitativo de caso, fue comparar y contrastar el curriculo vigente de la Escuela de Optometria de la UIAPR con las competencias y estandares requeridos por las agencias de acreditacion y de revalida. Con este proposito, decidimos realizar una revision y un analisis de documentos: el prontuario de cada uno de los cursos de los curriculos implantados en el 1993 y en el 2001; las competencias y estandares establecidos por las agencias de revalida y de acreditacion; y las estadisticas en las que se analiza el porcentaje de estudiantes que aprueban cada una de las partes de los examenes de revalida entre el 1998 al 2003. Se realizaron entrevistas dirigidas para dar apoyo y complementar la revision y el analisis de estos documentos. Los participantes de las entrevistas fueron tres estudiantes de la clase de optometria del 2004 (ultima clase del curriculo del 1993); tres estudiantes de la clase de optometria del 2005 (primera clase graduanda del curriculo vigente) y tres profesores y/o directores de los Departamentos de Ciencias Basicas, Ciencias Clinicas y Cuidado al Paciente. Esta investigacion se enmarco en el modelo de evaluacion curricular de discrepancia de Malcolm Provus y en el modelo de desarrollo basado en competencias. Uno de los hallazgos mas importantes del estudio es que los cambios que se implantaron al curriculo del 2001 no han logrado que los estudiantes mejoren su ejecucion en los examenes de revalida. Por otro lado, se encontro que el curriculo vigente atiende completamente los estandares de la practica de Optometria, pero no las competencias. Esta informacion fue validada mediante el uso de una tabla de cotejo para el analisis de los cursos y de la informacion obtenida de las entrevistas. El estudio determina y concluye que existen discrepancias entre los prontuarios de los cursos del curriculo y las competencias requeridas por la agencia de revalida. Segundo, que el Departamento de Ciencias Basicas es el

  19. Las dificultades de sentir: el rol de las emociones en la estigmatización del VIH/SIDA

    PubMed Central

    MARZÁN-RODRÍGUEZ, Melissa; VARAS-DÍAZ, Nelson

    2009-01-01

    Resumen El Virus de Inmunodeficiencia Humana (VIH) y el Síndrome de Inmunodeficiencia Adquirida (SIDA) han sido motivo de estigmatización para las personas que viven con ellos. Esta estigmatización se ha estudiado consecuentemente desde la perspectiva de opiniones de agentes estigmatizantes. Estas opiniones han obviado sistemáticamente el rol de las emociones en el proceso de estigmatización. Llevamos a cabo este estudio con el propósito de identificar el rol de las emociones en el proceso de estigmatización de las personas que viven con el virus (PVVS) por parte de profesionales de la salud. Para lograr este objetivo utilizamos un diseño exploratorio y cualitativo en el cual utilizamos la técnica de entrevistas semiestructuradas a profundidad. La muestra estuvo compuesta por 80 profesionales de la salud y estudiantes de las siguientes especialidades: psicología, trabajo social, medicina y enfermería. Los resultados reflejaron la existencia de emociones asociadas al VIH/SIDA tales como pena, lástima, compasión, asco, fobia y miedo entre los/as profesionales y estudiantes que participaron. Las personas participantes evidenciaron la necesidad de controlar sus emociones al interactuar con PVVS. Los resultados apuntan a la necesidad de explorar aquellos factores que mediatizan las emociones, tales como el contexto social en que se manifiestan y ante quiénes se revelan, para lograr entender a cabalidad el estigma que rodea al VIH/SIDA. PMID:20212916

  20. The type-material of Arctiinae (Lepidoptera, Erebidae) described by Burmeister and Berg in the collection of the Museo Argentino de Ciencias Naturales Bernardino Rivadavia (Buenos Aires, Argentina)

    PubMed Central

    Beccacece, Hernán M.; Vincent, Benoit; Navarro, Fernando R.

    2014-01-01

    Abstract Carlos G. Burmeister and Carlos Berg were among the most important and influential naturalists and zoologists in Argentina and South America and described 241 species and 34 genera of Lepidoptera. The Museo Argentino de Ciencias Naturales Bernardino Rivadavia (MACN) housed some of the Lepidoptera type specimens of these authors. In this study we present a catalogue with complete information and photographs of 11 Burmeister type specimens and 10 Berg type specimens of Phaegopterina, Arctiina and Pericopina (Lepidoptera, Erebidae, Arctiinae, Arctiini) housed in the MACN. Lectotypes or holotypes were designated where primary type specimens could be recognized; in some cases we were not able to recognize types. The catalogue also proposes nomenclatural changes and new synonymies: Opharus picturata (Burmeister, 1878), comb. n.; Opharus brunnea Gaede, 1923: 7, syn. n.; Hypocrisias jonesi (Schaus, 1894), syn. n.; Leucanopsis infucata (Berg, 1882), stat. rev.; Paracles argentina (Berg, 1877), sp. rev.; Paracles uruguayensis (Berg, 1886), sp. rev. PMID:25061380

  1. Birds of Antioquia: Georeferenced database of specimens from the Colección de Ciencias Naturales del Museo Universitario de la Universidad de Antioquia (MUA)

    PubMed Central

    Rozo, Andrea Morales; Valencia, Fernando; Acosta, Alexis; Parra, Juan Luis

    2014-01-01

    Abstract The department of Antioquia, Colombia, lies in the northwestern corner of South America and provides a biogeographical link among divergent faunas, including Caribbean, Andean, Pacific and Amazonian. Information about the distribution of biodiversity in this area is of relevance for academic, practical and social purposes. This data paper describes the dataset containing all bird specimens deposited in the Colección de Ciencias Naturales del Museo Universitario de la Universidad de Antioquia (MUA). We curated all the information associated with the bird specimens, including the georeferences and taxonomy, and published the database through the Global Biodiversity Information Facility network. During this process we checked the species identification and existing georeferences and completed the information when possible. The collection holds 663 bird specimens collected between 1940 and 2011. Even though most specimens are from Antioquia (70%), the collection includes material from several other departments and one specimen from the United States. The collection holds specimens from three endemic and endangered species (Coeligena orina, Diglossa gloriossisima, and Hypopirrhus pyrohipogaster), and includes localities poorly represented in other collections. The information contained in the collection has been used for biodiversity modeling, conservation planning and management, and we expect to further facilitate these activities by making it publicly available. PMID:24899851

  2. Las Campanas Stellar Library

    NASA Astrophysics Data System (ADS)

    Chilingarian, Igor; Zolotukhin, Ivan; Beletsky, Yuri; Worthey, Guy

    2015-08-01

    Stellar libraries are fundamental tools required to understand stellar populations in star clusters and galaxies as well as properties of individual stars. Comprehensive libraries exist in the optical domain, but the near-infrared (NIR) domain stays a couple of decades behind. Here we present the Las Campanas Stellar Library project aiming at obtaining high signal-to-noise intermediate-resolution (R=8000) NIR spectra (0.83<λ<2.5μm) for a sample of 1200 stars in the Southern sky using the Folded-port InfraRed Echelette spectrograph at the 6.5-m Magellan Baade telescope. We developed a dedicated observing strategy and customized the telescope control software in order to achieve the highest possible level of data homogeniety. As of 2015, we observed about 600 stars of all spectral types and luminosity classes making our library the largest homogeneous collection of stellar spectra covering the entire NIR domain. We also re-calibrated in flux and wavelength the two existing optical stellar libraries, INDO-US and UVES-POP and followed up about 400 non-variable stars in the NIR in order to get complete optical-NIR coverage. Worth mentioning that our current sample includes about 80 AGB stars and a few dozens of bulge/LMC/SMC stars.

  3. Explicación de las disparidades raciales en la salud neonatal en Brasil*

    PubMed Central

    Nyarko, Kwame A.; López-Camelo, Jorge; Castilla, Eduardo E.; Wehby, George L.

    2015-01-01

    Objetivos. Buscamos cuantificar la manera en que los efectos socioeconómicos, demográficos, geográficos y de atención de salud explican las disparidades raciales en las tasas de bajo peso al nacer y prematuridad en Brasil. Métodos. Utilizamos una muestra de 8 949 niños nacidos entre 1995 y el 2009 en 15 ciudades y 7 provincias de Brasil. Nos centramos en las disparidades en la prevalencia de bajo peso al nacer (< 2 500 g) y prematuridad (< 37 semanas de gestación) en recién nacidos de ascendencia solo africana o mezclada con otras ascendencias y de ascendencia solo europea. Usamos un modelo de descomposición para cuantificar la contribución de los factores conceptualmente pertinentes a esas disparidades. Resultados. El modelo permitió explicar entre 45% y 94% de las disparidades en cuanto al bajo peso al nacer y entre 64% y 94% de las disparidades en cuanto a la prematuridad entre los grupos de ascendencia africana y de ascendencia europea. Las diferencias en el uso de atención prenatal y en la ubicación geográfica fueron los factores más importantes, seguidos por las diferencias socioeconómicas. El modelo permitió explicar la mayoría de las disparidades en los recién nacidos de ascendencia africana mezclada y parte de las disparidades en los de ascendencia solo africana. Conclusiones. En las políticas públicas para mejorar la salud infantil se deben abordar las diferencias en cuanto a la atención prenatal y la ubicación geográfica a fin de reducir las disparidades en materia de salud entre los recién nacidos de ascendencia africana y los de ascendencia europea en Brasil.

  4. Evolution of NADPH-cytochrome P450 oxidoreductases (POR) in Apiales - POR 1 is missing.

    PubMed

    Andersen, Trine Bundgaard; Hansen, Niels Bjørn; Laursen, Tomas; Weitzel, Corinna; Simonsen, Henrik Toft

    2016-05-01

    The NADPH-dependent cytochrome P450 oxidoreductase (POR) is the obligate electron donor to eukaryotic microsomal cytochromes P450 enzymes. The number of PORs within plant species is limited to one to four isoforms, with the most common being two PORs per plant. These enzymes provide electrons to a huge number of different cytochromes P450s (from 50 to several hundred within one plant). Within the eudicotyledons, PORs can be divided into two major clades, POR 1 and POR 2. Based on our own sequencing analysis and publicly available data, we have identified 45 PORs from the angiosperm order Apiales. These were subjected to a phylogenetic analysis along with 237 other publicly available (NCBI and oneKP) POR sequences found within the clade Asterids. Here, we show that the order Apiales only harbor members of the POR 2 clade, which are further divided into two distinct subclades. This is in contrast to most other eudicotyledon orders that have both POR 1 and POR 2. This suggests that through gene duplications and one gene deletion, Apiales only contain members of the POR 2 clade. Three POR 2 isoforms from Thapsia garganica L., Apiaceae, were all full-length in an Illumina root transcriptome dataset (available from the SRA at NCBI). All three genes were shown to be functional upon reconstitution into nanodiscs, confirming that none of the isoforms are pseudogenes. PMID:26854662

  5. Portable exhauster POR-007/Skid E and POR-008/Skid F storage plan

    SciTech Connect

    Nelson, O.D.

    1998-07-25

    This document provides storage requirements for 1,000 CFM portable exhausters POR-O07/Skid E and POR-008/Skid F. These requirements are presented in three parts: preparation for storage, storage maintenance and testing, and retrieval from storage. The exhauster component identification numbers listed in this document contain the prefix POR-007 or POR-008 depending on which exhauster is being used.

  6. The Land Analysis System (LAS)

    NASA Technical Reports Server (NTRS)

    Lu, Yun-Chi; Irani, Fred M.

    1991-01-01

    The Land Analysis System (LAS) is an interactive software system, available in the public domain, for the analysis, display, and management of multispectral and other digital image data. The system was developed to support earth sciences research and development activities. LAS provides over 240 applications functions and utilities, a flexible user interface, complete on-line and hardcopy documentation, extensive image data file management, reformatting, and conversion utilities, and high level device independent access to image display hardware. The capabilities are summarized of the latest release of the system (version 5). Emphasis is given to the system portability and the isolation of hardware and software dependencies in this release.

  7. Las fulguraciones como manifestación de reconexión en el campo magnético solar

    NASA Astrophysics Data System (ADS)

    Bagalá, L. G.; Mandrini, M. C.; Rovira, M. G.; Démoulin, P.

    Las fulguraciones solares son fenómenos transitorios de liberación de energía que se desarrollan en las estructuras magnéticas de las regiones activas del Sol. Las fulguraciones pueden llegar a liberar hasta 1032 erg en 100 seg. en todo el rango electromagnético, y acelerar partículas. En este trabajo mostramos que la ubicación de los abrillantamientos en Hα de diversas fulguraciones está relacionado con las propiedades de las conexiones de las líneas del campo magnético de la región, como se espera por las teorías de reconexión en 3D recientemente desarrolladas (Démoulin et al, 1996a). El campo magnético coronal se extrapola del campo fotosférico observado suponiendo una configuración libre de fuerzas lineal. Por medio de un algoritmo se determinan las regiones donde existe un cambio drástico en la conectividad de las líneas de campo (límites ``cuasi-discontinuos'', o cuasi-separatrices CS). Las CS son bandas abiertas que identifican zonas donde el campo magnético se reconectará con más probabilidad y, siempre que las mismas sean lo suficientemente finas, se producirá allíla liberación de energía proveniente del campo magnético. Hemos encontrado que en todas las regiones fulgurantes estudiadas (Démoulin et al, 1996b) existen CS en los mismos lugares donde se observaron los abrillantamientos en Hα. Allídonde coinciden los abrillantamientos con las CS, éstas tienen un espesor menor que 1 Mm. Las líneas de campo coronales extrapoladas de nuestro modelo tienen sus orígenes fotosféricos a ambos lados de las CS, como se espera dados los recientes estudios de reconexión magnética en 3D. Estos resultados ponen a prueba los modelos presentes sobre fulguraciones solares.

  8. EMPACT: THE LAS VEGAS INTERAGENCY PILOT PROGRAM

    EPA Science Inventory

    ENPACT: The Las Vegas Interagency Pilot Project

    The Las Vegas Interagency Pilot Project of the EMPACT program has involved eleven efforts. These efforts are described in brief on the poster presentation. They include: Las Vegas Environmental Monitoring Inventory, the Qual...

  9. Consequences of POR mutations and polymorphisms.

    PubMed

    Miller, Walter L; Agrawal, Vishal; Sandee, Duanpen; Tee, Meng Kian; Huang, Ningwu; Choi, Ji Ha; Morrissey, Kari; Giacomini, Kathleen M

    2011-04-10

    P450 oxidoreductase (POR) transports electrons from NADPH to all microsomal cytochrome P450 enzymes, including steroidogenic P450c17, P450c21 and P450aro. Severe POR mutations A287P (in Europeans) and R457H (in Japanese) cause the Antley-Bixler skeletal malformation syndrome (ABS) plus impaired steroidogenesis (causing genital anomalies), but the basis of ABS is unclear. We have characterized the activities of ∼40 POR variants, showing that assays based on P450c17 activities, but not cytochrome c assays, correlate with the clinical phenotype. The human POR gene is highly polymorphic: the A503V sequence variant, which decreases P450c17 activities to ∼60%, is found on ∼28% of human alleles. A promoter polymorphism (∼8% of Asians and ∼13% of Caucasians) at -152 reduces transcriptional activity by half. Screening of 35 POR variants showed that most mutants lacking activity with P450c17 or cytochrome c also lacked activity to support CYP1A2 and CYP2C19 metabolism of EOMCC (a fluorogenic non-drug substrate), although there were some remarkable differences: Q153R causes ABS and has ∼30% of wild-type activity with P450c17 but had 144% of WT activity with CYP1A2 and 284% with CYP2C19. The effects of POR variants on CYP3A4, which metabolizes nearly 50% of clinically used drugs, was examined with multiple, clinically relevant drug substrates, showing that A287P and R457H dramatically reduce drug metabolism, and that A503V variably impairs drug metabolism. The degree of activity can vary with the drug substrate assayed, as the drugs can influence the conformation of the P450. POR is probably an important contributor to genetic variation in both steroidogenesis and drug metabolism. PMID:21070833

  10. Consequences of POR mutations and polymorphisms

    PubMed Central

    Miller, Walter L.; Agrawal, Vishal; Sandee, Duanpen; Tee, Meng Kian; Huang, Ningwu; Choi, Ji Ha; Morrissey, Kari; Giacomini, Kathleen M.

    2015-01-01

    P450 oxidoreductase (POR) transports electrons from NADPH to all microsomal cytochrome P450 enzymes, including steroidogenic P450c17, P450c21 and P450aro. Severe POR mutations A287P (in Europeans) and R457H (in Japanese) cause the Antley-Bixler skeletal malformation syndrome (ABS) plus impaired steroidogenesis (causing genital anomalies), but the basis of ABS is unclear. We have characterized the activities of ~40 POR variants, showing that assays based on P450c17 activities, but not cytochrome c assays, correlate with the clinical phenotype. The human POR gene is highly polymorphic: the A503V sequence variant, which decreases P450c17 activities to ~60%, is found on ~28% of human alleles. A promoter polymorphism (~8% of Asians and ~13% of Caucasians) at −152 reduces transcriptional activity by half. Screening of 35 POR variants showed that most mutants lacking activity with P450c17 or cytochrome c also lacked activity to support CYP1A2 and CYP2C19 metabolism of EOMCC (a fluorogenic non-drug substrate), although there were some remarkable differences: Q153R causes ABS and has ~30% of wild-type activity with P450c17 but had 144% of WT activity with CYP1A2 and 284% with CYP2C19. The effects of POR variants on CYP3A4, which metabolizes nearly 50% of clinically used drugs, was examined with multiple, clinically-relevant drug substrates, showing that A287P and R457H dramatically reduce drug metabolism, and that A503V variably impairs drug metabolism. The degree of activity can vary with the drug substrate assayed, as the drugs can influence the conformation of the P450. POR is probably an important contributor to genetic variation in both steroidogenesis and drug metabolism. PMID:21070833

  11. Detección y estudio mediante Fluorescencia Inducida por Láser de radicales libres formados por Disociación Multifotónica Infrarroja

    NASA Astrophysics Data System (ADS)

    Santos, M.; Díaz, L.; Torresano, J. A.; Rubio, L.; Samoudi, B.

    Una de las principales aplicaciones actuales de los procesos de disociación multifotónica inducidos por radiación láser infrarroja (DMI) es la producción de radiales libres, con el fin de estudiar sus propiedades cinéticas y espectroscópicas. La disociación de moléculas poliatómicas en el IR con láseres de CO2 tiene lugar desde la superficie de energía molecular mas baja y conduce generalmente a la formación de fragmentos en el estado electrónico fundamental, con diversos grados de excitación vibracional. En el Grupo de Procesos Multifotónicos del Instituto de Estructura de la Materia del C.S.I.C. hemos puesto a punto la técnica de Fluorescencia Inducida por Láser (LIF) para la detección y análisis en tiempo real de los fragmentos producidos en la DMI inducida mediante uno o dos campos láseres de diferentes longitudes de onda. Objetivos de nuestro trabajo han sido el estudio de los canales de disociación mayoritarios y de las especies transitoria producidas, así como de la distribución de energía interna con que éstas son generadas. En particular hemos detectado mediante LIF las especies: C2, CF, CH, SiH2, CF2, CH2, SiHCl, y CF3 a partir de la disociación de, entre otras, las siguientes moléculas: C2H3Br, C3F6, C4H8Si, C2H5ClSi y CH5ClSi. En este trabajo presentamos algunos de los resultados obtenidos mediante el estudio por LIF de estos radicales: estudio temporal de la señal LIF obtenida con determinación de tiempos de vida, espectros de excitación y fluorescencia, temperaturas vibracionales de formación, variación de la intensidad LIF con el tiempo de retraso entre los láseres de disociación y prueba, etc.

  12. Encefalitis por anticuerpos contra el receptor de NMDA: experiencia con seis pacientes pediátricos. Potencial eficacia del metotrexato

    PubMed Central

    Bravo-Oro, Antonio; Abud-Mendoza, Carlos; Quezada-Corona, Arturo; Dalmau, Josep; Campos-Guevara, Verónica

    2016-01-01

    Introducción La encefalitis por anticuerpos contra el receptor de N-metil-D-aspartato (NMDA) es una entidad cada vez más diagnosticada en edad pediátrica. A diferencia de los adultos, en muchos casos no se asocia a tumores y las manifestaciones iniciales en niños más frecuentes son crisis convulsivas y trastornos del movimiento, mientras que en los adultos predominan las alteraciones psiquiátricas. Casos clínicos Presentamos seis casos pediátricos confirmados con anticuerpos contra la subunidad NR1 del receptor de NMDA en suero y líquido cefalorraquídeo. Cinco de los casos comenzaron con crisis convulsivas como manifestación clínica inicial antes de desarrollar el cuadro clásico de esta entidad. En todos los casos se utilizaron esteroides como primera línea de tratamiento, con los que sólo se observó control de las manifestaciones en uno, por lo que el resto de los pacientes requirió inmunomoduladores de segunda línea. Todos los pacientes recibieron metotrexato como tratamiento inmunomodulador para evitar recaídas y la evolución fue a la mejoría en todos ellos. Conclusiones En nuestra serie de pacientes con encefalitis por anticuerpos contra el receptor de NMDA, ninguno se asoció a tumores. Todos los casos recibieron metotrexato por lo menos durante un año, no observamos eventos adversos clínicos ni por laboratorio, ni hubo secuelas neurológicas ni recaídas durante el tratamiento. Aunque es una serie pequeña y es deseable incrementar el número y tiempo de evolución, consideramos el metotrexato una excelente alternativa como tratamiento inmunomodulador para esta patología. PMID:24150952

  13. Desarrollo de una Interfaz de Control para un Observatorio Astronómico Robotizado con fines educativos en la Facultad de Ciencias Exactas; Físicas y Naturales de la UNSJ

    NASA Astrophysics Data System (ADS)

    Pogrebinsky, L.; Francile, C.

    We report the development and the construction of an Interface to Control a robotized Astronomical Observatory (ICOA), which allows to control the operation of an observatory based on a Meade LX200 telescope. The interface operates together with a computer to control and supervise all the local variables of the observatory, and can take the control of it in risky situations. It serves as a link among the control computer and all the necessary devices for the astronomical observation such as the telescope, the dome, the weather station, the CCD camera, the calibration devices and the security devices. The computer receives orders from an operator who can be or not at the site of observation. The goal of this robotized observatory is the operation in a secure, autonomous and unattended way, with the purpose of to be used remotely by the students of the "Facultad de Ciencias Exactas, Físicas y Naturales" of the UNSJ. FULL TEXT IN SPANISH

  14. Contribución al flujo infrarrojo de las estrellas Be de la recombinación dielectrónica del MgII

    NASA Astrophysics Data System (ADS)

    Cruzado, A.; di Rocco, H.; Ringuelet, A.

    Para evaluar la contribución del proceso de recombinación dielectrónica del átomo de MgII al exceso de flujo infrarrojo observado en las estrellas Be, calculamos la energía emitida en las líneas originadas por este proceso. Se evaluaron los efectos de las condiciones físicas del medio, como la temperatura electrónica y la densidad electrónica, sobre el flujo emitido. Se consideró también la influencia de una posible opacidad.

  15. Diagnóstico diferencial en la encefalitis por anticuerpos contra el receptor NMDA

    PubMed Central

    González-Valcárcel, J.; Rosenfeld, M.R.; Dalmau, J.

    2011-01-01

    Resumen Introducción La encefalitis por anticuerpos contra el receptor de NMDA (NMDAR) suele desarrollarse como un síndrome característico de evolución multifásica y diagnóstico diferencial amplio. Pacientes Presentamos a 2 pacientes diagnosticadas de encefalitis por anticuerpos NMDAR con un cuadro clínico típico, pero que inicialmente señaló otras etiologías. Discusión La afectación frecuente de pacientes jóvenes con manifestaciones psiquiátricas prominentes indica frecuentemente otras consideraciones diagnósticas; las más frecuentes son las encefalitis virales, los procesos psiquiátricos y el síndrome neuroléptico maligno. Varios síndromes previamente definidos de manera parcial o descriptiva en adultos y pacientes pediátricos probablemente eran casos de encefalitis anti-NMDAR. Conclusiones La encefalitis anti-NMDAR debe considerarse en pacientes jóvenes con manifestaciones psiquiátricas subagudas, movimientos anormales y alteraciones autonómicas. La caracterización clínica e inmunológica de esta enfermedad ha llevado a la identificación de nuevos anticuerpos que afectan a procesos de memoria, aprendizaje, conducta y psicosis. PMID:20964986

  16. Structural Insights into the PorK and PorN Components of the Porphyromonas gingivalis Type IX Secretion System

    PubMed Central

    Gorasia, Dhana G.; Veith, Paul D.; Hanssen, Eric G.; Glew, Michelle D.; Sato, Keiko; Yukitake, Hideharu; Nakayama, Koji; Reynolds, Eric C.

    2016-01-01

    The type IX secretion system (T9SS) has been recently discovered and is specific to Bacteroidetes species. Porphyromonas gingivalis, a keystone pathogen for periodontitis, utilizes the T9SS to transport many proteins including the gingipain virulence factors across the outer membrane and attach them to the cell surface via a sortase-like mechanism. At least 11 proteins have been identified as components of the T9SS including PorK, PorL, PorM, PorN and PorP, however the precise roles of most of these proteins have not been elucidated and the structural organization of these components is unknown. In this study, we purified PorK and PorN complexes from P. gingivalis and using electron microscopy we have shown that PorN and the PorK lipoprotein interact to form a 50 nm diameter ring-shaped structure containing approximately 32–36 subunits of each protein. The formation of these rings was dependent on both PorK and PorN, but was independent of PorL, PorM and PorP. PorL and PorM were found to form a separate stable complex. PorK and PorN were protected from proteinase K cleavage when present in undisrupted cells, but were rapidly degraded when the cells were lysed, which together with bioinformatic analyses suggests that these proteins are exposed in the periplasm and anchored to the outer membrane via the PorK lipid. Chemical cross-linking and mass spectrometry analyses confirmed the interaction between PorK and PorN and further revealed that they interact with the PG0189 outer membrane protein. Furthermore, we established that PorN was required for the stable expression of PorK, PorL and PorM. Collectively, these results suggest that the ring-shaped PorK/N complex may form part of the secretion channel of the T9SS. This is the first report showing the structural organization of any T9SS component. PMID:27509186

  17. Structural Insights into the PorK and PorN Components of the Porphyromonas gingivalis Type IX Secretion System.

    PubMed

    Gorasia, Dhana G; Veith, Paul D; Hanssen, Eric G; Glew, Michelle D; Sato, Keiko; Yukitake, Hideharu; Nakayama, Koji; Reynolds, Eric C

    2016-08-01

    The type IX secretion system (T9SS) has been recently discovered and is specific to Bacteroidetes species. Porphyromonas gingivalis, a keystone pathogen for periodontitis, utilizes the T9SS to transport many proteins including the gingipain virulence factors across the outer membrane and attach them to the cell surface via a sortase-like mechanism. At least 11 proteins have been identified as components of the T9SS including PorK, PorL, PorM, PorN and PorP, however the precise roles of most of these proteins have not been elucidated and the structural organization of these components is unknown. In this study, we purified PorK and PorN complexes from P. gingivalis and using electron microscopy we have shown that PorN and the PorK lipoprotein interact to form a 50 nm diameter ring-shaped structure containing approximately 32-36 subunits of each protein. The formation of these rings was dependent on both PorK and PorN, but was independent of PorL, PorM and PorP. PorL and PorM were found to form a separate stable complex. PorK and PorN were protected from proteinase K cleavage when present in undisrupted cells, but were rapidly degraded when the cells were lysed, which together with bioinformatic analyses suggests that these proteins are exposed in the periplasm and anchored to the outer membrane via the PorK lipid. Chemical cross-linking and mass spectrometry analyses confirmed the interaction between PorK and PorN and further revealed that they interact with the PG0189 outer membrane protein. Furthermore, we established that PorN was required for the stable expression of PorK, PorL and PorM. Collectively, these results suggest that the ring-shaped PorK/N complex may form part of the secretion channel of the T9SS. This is the first report showing the structural organization of any T9SS component. PMID:27509186

  18. Las Cumbres Observatory Global Telescope

    NASA Astrophysics Data System (ADS)

    Brown, Timothy M.; Rosing, W.; Pickles, A.; Howell, D. A.

    2009-05-01

    Las Cumbres Observatory Global Telescope (LCOGT) is a privately-funded observatory dedicated to time-domain astronomy. Our main observing tool will be a homogeneous world-wide network of 12 x 1m optical telescopes, each equipped for both imaging and spectroscopy. We will also continue to operate 2m telscopes in Hawaii and Australia, and we plan to deploy a few tens of 0.4m imaging telescopes for education and for bright-object research. LCOGT has membership in the Pan-STARRS1 consortium, in the Palomar Transient Factory (PTF), and in LSST. In accord with these affiliations, our staff's scientific interests are concentrated in (but not restricted to) the areas of extrasolar planets, extragalactic transients (especially SNe), and pulsating stars. In this poster we describe the observatory in general terms, including its research agenda, its telescope deployment plans and schedule, its notable technical challenges, and its anticipated methods of working with the wider astronomical community. For more detailed information about LCOGT's aims and projects, please see the related posters in this session.

  19. Investigaccion-accion en la sala de clases sobre las creencias de la cultura de la ciencia de un grupo de estudiantes universitarios y su relacion reciproca con el aprendizaje de las ciencias biologicas

    NASA Astrophysics Data System (ADS)

    Cordova-Santiago, Lizzette Astrid

    La investigacion---accion que se llevo a cabo en la sala de clases tenia como punto de partida las creencias de la cultura de la ciencia de un grupo de estudiantes universitarios para luego examinar sus implicaciones en el proceso de aprendizaje de las Ciencias Biologicas. ¿Que se supone que hagan las creencias en relacion con el aprendizaje? ¿En que consiste incorporar este aspecto a la practica educativa universitaria? Utilizando el modelo de Kemmis y McTaggart (1987) la investigacion-accion se planteo como un proceso dinamico en cuatro momentos en espiral constituidos por la planificacion, la accion, la observacion y la reflexion. Cada una de las fases tuvo una intencion retrospectiva y prospectiva formando una espiral de autorreflexion del conocimiento y la accion. Se llevaron a cabo audio grabaciones en clases y analisis de documentos. Ademas, la profesora-investigadora hizo un portafolio para reflexionar sobre las creencias de la cultura de la ciencia que tienen los estudiantes y las creencias del aprendizaje que tiene la profesora y sobre como la comprension de estos elementos ayudo a mejorar su practica educativa a traves del tiempo. Los resultados obtenidos apuntan a que las creencias de la cultura de la ciencia que tiene el grupo de estudiantes son diversas. Ellos si creen que la ciencia tiene una cultura la cual describieron como: complicada y desconocida que evoluciona constantemente, que es un conjunto de metodos, que es altamente tecnologica, que resuelve problemas de salud, ayuda a interpretar la realidad del mundo que los rodea y su origen y que existen unas intersecciones entre la ciencia y el poder. Sobre las creencias del proceso de aprendizaje de la profesora-investigadora, estas senalan que el modelaje de actores, la vision de la academia que tiene ella asi como la participacion y negociacion entre todos los involucrados en el proceso educativo, son factores que inciden en el proceso de aprendizaje.

  20. Overview of the land analysis system (LAS)

    USGS Publications Warehouse

    Quirk, Bruce K.; Olseson, Lyndon R.

    1987-01-01

    The Land Analysis System (LAS) is a fully integrated digital analysis system designed to support remote sensing, image processing, and geographic information systems research. LAS is being developed through a cooperative effort between the National Aeronautics and Space Administration Goddard Space Flight Center and the U. S. Geological Survey Earth Resources Observation Systems (EROS) Data Center. LAS has over 275 analysis modules capable to performing input and output, radiometric correction, geometric registration, signal processing, logical operations, data transformation, classification, spatial analysis, nominal filtering, conversion between raster and vector data types, and display manipulation of image and ancillary data. LAS is currently implant using the Transportable Applications Executive (TAE). While TAE was designed primarily to be transportable, it still provides the necessary components for a standard user interface, terminal handling, input and output services, display management, and intersystem communications. With TAE the analyst uses the same interface to the processing modules regardless of the host computer or operating system. LAS was originally implemented at EROS on a Digital Equipment Corporation computer system under the Virtual Memorial System operating system with DeAnza displays and is presently being converted to run on a Gould Power Node and Sun workstation under the Berkeley System Distribution UNIX operating system.

  1. Resonances and Tides in Natural Satellites Systems. (Breton Title: Ressonâncias e Marés em Sistemas de Satélites Naturais.) Resonancias y Mareas en Sistemas de Satélites Naturales

    NASA Astrophysics Data System (ADS)

    Callegari, Nelson, Jr.

    2006-12-01

    sica, e não a descrição detalhada dos conceitos aqui discutidos. Describimos en este trabajo algunos aspectos de la dinámica de resonancias de movimientos promedio. Será dado un énfasis mayor al caso de las resonancias entre satélites regulares de los planetas gigantes, aunque también son discutidos brevemente algunos aspectos de la física de resonancias en sistemas panetarios extrasolares. La importancia del estudio de las resonancias en sistemas de satélites es discutida más detalladamente através de ejemplos, mostrando cómo ciertas resonancias y los efectos de disipación por mareas pueden ser la clave de parte de la explicación de algunos fenómenos aún no comprendidos en el Sistema Solar. Entre varios ejemplos se destacan el problema de la superficie remodelada del satélite Enceladus, la existencia de volcanes activos en Io y la posible existencia de un océano subterráneo en Europa. Este trabajo tiene como objetivo la divulgación de algunos tópicos en Mecánica Celeste y Planetología para un público universitario de ciencias exactas, en particular Astronomía y Física, y no la descripción detallada de los conceptos aquí discutidos.

  2. LAS Language Arts Supplement, English. Revised Edition.

    ERIC Educational Resources Information Center

    DeAvila, Edward A.; Duncan, Sharon E.

    This collection of over 100 games and activities is intended to increase oral proficiency among Spanish-speaking children without requiring reading skills. The collection grew out of the desire to provide remedies for specific linguistic weaknesses in English as identified by the Language Assessment Scales (LAS). Because tongue twisters, riddles…

  3. 'NuMex Las Cruces' Cayenne pepper

    Technology Transfer Automated Retrieval System (TEKTRAN)

    ‘NuMex Las Cruces’ is a high-yielding, high-heat, cayenne pepper with a maturity similar to that of ‘Large Red Thick’, an early maturing cayenne cultivar. In addition, it possesses resistance to curly top virus, having resistance to at least three Curtovirus species: Beet curly top virus (BCTV; for...

  4. Pressure leaching las cruces copper ore

    NASA Astrophysics Data System (ADS)

    Berezowsky, R. M.; Xue, T.; Collins, M. J.; Makwana, M.; Barton-Jones, I.; Southgate, M.; Maclean, J. K.

    1999-12-01

    A hydrometallurgical process was developed for treating the Las Cruces massive sulfide-ore deposit located near Seville, Spain. A two-stage countercurrent leach process, consisting of an atmospheric leach and a pressure leach, was developed to effectively leach copper from the copper-bearing minerals and to generate a solution suitable for the subsequent solvent-extraction and copper-electrowinning operations. The results of batch and continuous miniplant tests are presented.

  5. LANDSCAPE CHANGE OF THE LAS VEGAS VALLEY, 1972 TO 1998

    EPA Science Inventory

    Las Vegas has become one of the fastest growing metropolitan areas in the United States. The cities population has doubled from 1980 to 1994 and in 1995 Las Vegas has surpassed the one million mark. The population of Las Vegas is currently growing at a rate of 7 percent annually....

  6. The PorX Response Regulator of the Porphyromonas gingivalis PorXY Two-Component System Does Not Directly Regulate the Type IX Secretion Genes but Binds the PorL Subunit

    PubMed Central

    Vincent, Maxence S.; Durand, Eric; Cascales, Eric

    2016-01-01

    The Type IX secretion system (T9SS) is a versatile multi-protein complex restricted to bacteria of the Bacteriodetes phylum and responsible for the secretion or cell surface exposition of diverse proteins that participate to S-layer formation, gliding motility or pathogenesis. The T9SS is poorly characterized but a number of proteins involved in the assembly of the secretion apparatus in the oral pathogen Porphyromonas gingivalis have been identified based on genome substractive analyses. Among these proteins, PorY, and PorX encode typical two-component system (TCS) sensor and CheY-like response regulator respectively. Although the porX and porY genes do not localize at the same genetic locus, it has been proposed that PorXY form a bona fide TCS. Deletion of porX in P. gingivalis causes a slight decrease of the expression of a number of other T9SS genes, including sov, porT, porP, porK, porL, porM, porN, and porY. Here, we show that PorX and the soluble cytoplasmic domain of PorY interact. Using electrophoretic mobility shift, DNA-protein co-purification and heterologous host expression assays, we demonstrate that PorX does not bind T9SS gene promoters and does not directly regulate expression of the T9SS genes. Finally, we show that PorX interacts with the cytoplasmic domain of PorL, a component of the T9SS membrane core complex and propose that the CheY-like PorX protein might be involved in the dynamics of the T9SS.

  7. Obtención de la curva de luz en la ocultación de 35 Sgr por Júpiter el 6 de marzo de 1996

    NASA Astrophysics Data System (ADS)

    Paolantonio, S.; Duffard, R.; Carranza, G.

    La ocultación de la estrella de quinta magnitud 35 Sgr por Júpiter, se produjo el 6 de Marzo de 1996 a las 13 hs. TU. El objetivo era medir el cambio del flujo de la estrella en el ingreso y egreso por el limbo del planeta. Con estos datos se pueden determinar parámetros físicos del planeta (radio, eccentricidad) y de su atmósfera (escala de altura, temperatura, densidad, presión) Para lograr ésto se programó la cámara CCD TH 7896 1024 x 1025 instalada en el telescopio de 1.54 m de Bosque Alegre con el objetivo de lograr 2 imágenes por segundo. De esta forma se obtuvieron 2100 imágenes de la inmersión y otras tantas de la emersión. Hubo que tener grandes precauciones para evitar la saturación del CCD ya que la observación se realizó de día. En este momento las imágenes se encuentran en el Department of Planetary Sciences, Lunar and Planetary Laboratory, University of Arizona, para su reducción.

  8. Las líneas de aluminio neutro como diagnóstico cromosférico

    NASA Astrophysics Data System (ADS)

    Fernández Borda, R.; Mauas, P. J. D.

    Se presenta un modelo atómico para el cálculo de las lí neas del Aluminio neutro que se forman en la cromósfera solar. En particular, se estudia la línea λ 3961 Å, que, por estar muy próxima a la lí nea H del Ca II y a Hɛ es muy frecuentemente observada. Observaciones en esta lí nea obtenidas con el espectrógrafo a instalarse en el CASLEO, serán utilizadas para el estudio de fulguraciones solares.

  9. Estimaciones de Prevalencia del VIH por Género y Grupo de Riesgo en Tijuana, México: 2006

    PubMed Central

    Iñiguez-Stevens, Esmeralda; Brouwer, Kimberly C.; Hogg, Robert S.; Patterson, Thomas L.; Lozada, Remedios; Magis-Rodriguez, Carlos; Elder, John P.; Viani, Rolando M.; Strathdee, Steffanie A.

    2010-01-01

    OBJETIVO Estimar la prevalencia del VIH en adultos de 15-49 años de edad en Tijuana, México - en la población general y en subgrupos de riesgo en el 2006. METODOS Se obtuvieron datos demográficos del censo Mexicano del 2005, y la prevalencia del VIH se obtuvo de la literatura. Se construyó un modelo de prevalencia del VIH para la población general y de acuerdo al género. El análisis de sensibilidad consistió en estimar errores estándar del promedio-ponderado de la prevalencia del VIH y tomar derivados parciales con respecto a cada parámetro. RESULTADOS La prevalencia del VIH es 0.54%(N = 4,347) (Rango: 0.22%–0.86%, (N = 1,750–6,944)). Esto sugiere que 0.85%(Rango: 0.39%–1.31%) de los hombres y 0.22%(Rango: 0.04%–0.40%) de las mujeres podrían ser VIH-positivos. Los hombres que tienen sexo con hombres (HSH), las trabajadoras sexuales usuarias de drogas inyectables (MTS-UDI), MTS-noUDI, mujeres UDI, y los hombres UDI contribuyeron las proporciones más elevadas de personas infectadas por el VIH. CONCLUSIONES El número de adultos VIH-positivos entre subgrupos de riesgo en la población de Tijuana es considerable, marcando la necesidad de enforcar las intervenciones de prevención en sus necesidades específicas. El presente modelo estima que hasta 1 en cada 116 adultos podrían ser VIH-positivos. PMID:19685824

  10. Abundancias químicas de las estrellas CP del grupo HgMn μ Leporis y 53 Tauri. II. Boro, Berilio, Carbono, Magnesio, Aluminio y Silicio

    NASA Astrophysics Data System (ADS)

    López García, Z.; Malaroda, S. M.; Faraggiana, R.

    Se determinan las abundancias químicas de los elementos más livianos presentes en dos estrellas CP del grupo HgMn, μ Lep y 53 Tau, utilizando espectros IUE de alta resolución y técnicas de cálculo de espectros sintéticos. Para el cálculo de las líneas se utiliza la lista mas completa de datos atómicos disponible y el programa SYNTHE. Para el cálculo de la abundancia de un elemento se comparan, para cada imagen, los perfiles observados del mayor número de líneas presentes con los perfiles calculados obtenidos por variación de las abundancias iniciales, reteniendo la abundancia para la cual el acuerdo entre las líneas observadas y calculadas es considerado visualmente el mejor. Los resultados obtenidos son comparados con los estimados por la teoría de la difusión.

  11. Prevalencia y tamizaje del Trastorno por Déficit de Atención con Hiperactividad en Costa Rica

    PubMed Central

    Weiss, Nicholas T.; Schuler, Jovita; Monge, Silvia; McGough, James J.; Chavira, Denise; Bagnarello, Monica; Herrera, Luis Diego; Mathews, Carol A.

    2015-01-01

    Resumen La investigación tuvo como propósito estimar la prevalencia del Trastorno por Déficit de Atención con Hiperactividad (TDAH) en Costa Rica y determinar si la versión en español del cuestionario Swanson Nolan and Pelham Scale IV (SNAP-IV) es un instrumento de tamizaje útil en una población de niños y niñas escolares costarricenses. El instrumento fue entregado a padres y maestros de 425 niños entre 5 y 13 años de edad (promedio = 8.8). Todos fueron evaluados con el instrumento Swanson, Kotkin, Agler, M-Flynn and Pelham Scale (SKAMP). Su diagnóstico fue confirmado con una entrevista clínica. La sensibilidad y la especificidad del SNAP-IV fueron evaluadas como predictores de criterios de diagnóstico según el DSM-IV. La prevalencia puntual en la muestra del TDAH fue del 5%. El tamizaje más preciso lo hizo el SNAP-IV completado por el maestro en un corte de 20%, con una sensibilidad de 96% y una especificidad de un 82%. La sensibilidad de los instrumentos completados por los padres fue más baja que aquella de los maestros. El SNAP-IV completado por las maestras con un corte aislando el 20% de los mayores puntajes categorizó correctamente a un 87% de los sujetos. PMID:22432094

  12. Risk, Las Vegas, and "The Deer Hunter".

    PubMed

    Ratzan, R M

    1987-01-01

    Risk is inherent in every medical setting. Emergency medicine is an especially risky specialty for both patient and emergency physician, eg, the risk of death from trauma and the risk of adverse outcome from medical intervention that can't wait for more favorable circumstances. Risk assessment (the numerical quantification of certain risks) and risk acceptability (the qualification of risks as acceptable or not) are helpful concepts in understanding risk. Comparing the risks and attitudes toward these risks of gambling in Las Vegas and the movie "The Deer Hunter" with emergency medicine demonstrates the need for emergency physicians to become involved in measures designed to promote prophylactic risk avoidance. PMID:3584918

  13. Inversor Resonante de Tres Elementos L-LC con Caracteristica Cortocircuitable para Aplicaciones de Calentamiento por Induccion

    NASA Astrophysics Data System (ADS)

    Espi Huerta, Jose Miguel

    Los generadores de calentamiento por induccion son puentes inversores con carga resonante, cuya mision es basicamente crear una corriente sinusoidal de gran amplitud sobre la "bobina de caldeo", que forma parte del tanque resonante. En el interior de esta bobina se introduce la pieza que se desea calentar. EI campo magnetico creado induce corrientes superficiales (corrientes de Foucault) sobre la pieza, que producen su calentamiento. Los tanques resonantes (tambien llamados osciladores) utilizados en la actualidad son el resonante serie y el resonante paralelo. Aunque ya desde hace algun tiempo se vienen construyendo generadores de alta potencia basados en estos dos osciladores, el exito nunca ha. sido completo en ninguno de los dos casos. Tal y como se explica en la introduccion de esta memoria, los puentes inversores utilizados deben operar sobre una carga inductiva (corriente retrasada) para evitar el fenomeno de la recuperacion inversa de sus diodos y la consiguiente ruptura de los transistores. De la restriccion topologica anterior se deduce que el generador paralelo debe conmutar a frecuencias inferiores a la resonancia, y el serie a frecuencias superiores. A esta restriccion topologica hay que unir otra que es exclusiva del calentamiento por induccion: La corriente por la bobina de caldeo debe ser sinusoidal. De no ser asi, resultaria imposible disponer toda la potencia de calentamiento sobre la pieza en el espesor requerido por la aplicacion. Como consecuencia, los inversores no pueden operar por debajo de la frecuencia de resonancia del oscilador, pues en ese caso se amplifican los armonicos de orden superior de la tension/corriente de entrada situados sobre la resonancia, con la consiguiente distorsion de la corriente de salida. La conjuncion de las dos restricciones anteriores obligan al inversor paralelo a funcionar a la frecuencia de resonancia del oscilador. Esto imposibilita un control por variacion de frecuencia, regulandose la potencia desde la

  14. Advanced Airborne CO2 LAS System

    NASA Astrophysics Data System (ADS)

    Dobler, J. T.; Braun, M. G.; McGregor, D. P.; Erxleben, W. H.; Browell, E. V.; Harrison, F. W.

    2009-12-01

    A unique airborne Laser Absorption Spectroscopy (LAS) system has been developed by ITT Space Systems, LLC to address the needs of the National Research Council Decadal Survey Tier 2 mission for Active Sensing of CO2 Emissions over Nights, Days and Seasons (ASCENDS). This instrument has undergone multiple airborne field tests in cooperation with our partners at NASA Langley Research Center (LaRC). The instrument was built largely with off-the-shelf components and uses high reliability telecom components, including lasers, modulators and fiber amplifiers as the transmitter. Multiple wavelengths are transmitted simultaneously from a single collimator and the return signal is collected by a simple 8” telescope that is fiber coupled to a HgCdTe APD. The analog signal is sampled with a high resolution scope card housed in a National Instruments PXI chassis and the digitized signal is then passed through our custom-built software-based lock-in processing system which allows separation of the signals from the individual wavelengths. The separated signals are then used in the standard Differential Absorption Lidar (DIAL) relations to determine the integrated column differential optical depth. This presentation will give a detailed overview of this multi-frequency, single-beam, synchronous lock-in LAS instrument including the basic methodology of the measurement. Recent improvements in the lock-in methodology designed to eliminate the effects of multi- path fading and frequency dependence of the electronic components will also be discussed.

  15. Variaciones seculares de período en las RR Lyrae de ω~Centauri

    NASA Astrophysics Data System (ADS)

    Marraco, H. G.; Milesi, G. E.

    Utilizando 689 observaciones de 35 estrellas RR Lyrae del cúmulo globular ω Centauri hemos obtenido nuevas determinaciones de sus períodos y sus correspondientes variaciones seculares. Las observaciones fueron obtenidas de la literatura con la excepción de un grupo 66 determinaciones que se presentan por vez primera aquí. Utilizando el parámetro testigo σ descripto en Marraco & Muzzio (Publ. Astron. Soc. Pacific 92, 700, 1980), hemos realizado un ajuste bidimensional en P y β (donde β es la variación secular del período). Con este fin la totalidad de las 689 observaciones fueron llevadas a un sistema fotométrico común. Para esto se realizó un cuidadoso análisis de los numerosos errores en la identificación de las estrellas de las series de comparación. Los resultados de los ajustes bidimensionales fueron analizados utilizando técnicas de procesamiento de imágenes. Con este fin el parámetro de ajuste σ fue representado como función de P y β. En las imágenes resultantes se buscaron los mínimos y al menor de ellos se lo aceptó como período instantáneo verdadero y su variación secular β. La determinación precisa de cada parámetro se realizó mediante ajuste de gaussianas y se determinaron sus errores. A modo de ejemplo la variable #8 fue analizada en una matriz de 501 × 501 elementos representando el parámetro σ para valores comprendidos entre 0,521034 < P < 0,521534 dias y -150×10-10 < β < +150×10-10 dias/dia. El mejor período instantáneo (correspondiente a la época DJ=2.426.908) y su variación secular son P = 0,5212859±0,0000001 días y β 14,012±,010×10-10 días/día respectivamente. Con estos valores el parámetro testigo resulta σ= 0,127 . Si no se tiene en cuenta la variación secular del período y se busca aquél de mejor ajuste para β = 0, se obtiene P = 0,5212960 días, pero entonces el parámetro de ajuste resulta tan alto como σ = 0,23 .

  16. "Estudio tribologico de aceros para moldes. Aplicacion al moldeo por inyeccion de polibutilentereftalato reforzado con fibra de vidrio"

    NASA Astrophysics Data System (ADS)

    Martinez Mateo, Isidoro Jose

    fabricacion del molde, tienen una gran influencia sobre su comportamiento en servicio a lo largo de la vida util del molde. En la primera parte del presente estudio, a partir de ensayos punzon sobre disco, se ha determinado la relacion entre la resistencia al desgaste y la dureza de aceros para moldes obtenidos a partir de bloques de gran espesor, estudiando los principales mecanismos de desgaste que tienen lugar. A continuacion, con el fin de determinar el dano superficial que sufren los aceros para moldes en condiciones reales de inyeccion, se han estudiado distintos tipos de aceros utilizados comercialmente en moldes de inyeccion de polimeros y materiales compuestos, seleccionando las condiciones de operacion para determinar la variacion de la rugosidad superficial del acero en funcion del material inyectado, del numero de operaciones sucesivas de inyeccion y de la orientacion del flujo de inyeccion, mediante tecnicas de perfilometria optica y microscopia electronica de barrido. Ademas del dano superficial sufrido por el acero con el numero de piezas inyectadas, tambien se ha determinado la evolucion de la rugosidad superficial de los materiales inyectados, polibutilentereftalato (PBT) puro y materiales compuestos derivados de PBT por adicion de un 20 o un 50% en peso de fibra de vidrio. En el caso de las piezas inyectadas, se ha caracterizado su microestructura en funcion del flujo de inyeccion y de la densidad de fibra, se han determinado sus propiedades termicas y dinamico-mecanicas, asi como la variacion de la rugosidad superficial de las piezas inyectadas con el numero de operaciones de inyeccion y con la geometria de las distintas secciones de las piezas. Finalmente, se ha evaluado la resistencia a la abrasion de PBT reforzado con un 50% de fibra, en funcion del numero de piezas inyectadas y de la direccion de rayado con respecto a la orientacion del flujo de inyeccion.

  17. Las Vegas Basin Seismic Response Project: Preliminary Results From Seismic Refraction Experiments, Las Vegas, NV.

    NASA Astrophysics Data System (ADS)

    Zaragoza, S. A.; Snelson, C. M.; Harder, S. H.; Kaip, G.; Luke, B.; Buck, B. J.; Hanson, A. D.

    2002-12-01

    In May and September 2002, seismic refraction data were acquired in the Las Vegas basin. Located in the southern Basin and Range province, the cities of Las Vegas, North Las Vegas, and Henderson sit atop a fault-bounded basin with a depth of up to 5 km and basin dimensions of roughly 60 km wide (east-west) by 50 km in length (north-south). Previous isostatic gravity, seismic reflection, and aeromagnetic studies indicate that a series of sub-basins exist beneath the unconsolidated basin fill, with the deepest sub-basin occurring 5 km west of the fault block bounding the eastern edge of the basin (Frenchman Mountain). The basin is significantly deeper along its northern extremity, following the path of the fault block bounding the northern edge of the basin (Las Vegas Valley Shear Zone), and along the western edge of Frenchman Mountain. Recent, paleoseismic studies have indicated that faults in the Las Vegas region have the potential for an earthquake of M6.5 to 7.0. It is estimated that a M6.9 earthquake in the basin could produce about 11 billion dollars in damage and a significant number of deaths and/or injuries. In addition, an equivalent or larger event in the Death Valley fault zone, 150 km distance, would also be devastating to the metropolitan area of approximately 1.5 million residents. Therefore, it is essential to understand the seismic hazard posed to the Las Vegas region. This project is part of a larger collaborative effort to characterize the basin and its response to ground shaking. The University of Nevada, Las Vegas with assistance from the University of Texas at El Paso, students from UNLV and UTEP, volunteers from the community and several students from Centennial High school deployed 432 portable seismic recorders ("Texans") throughout the valley. Shot point locations were located at three quarries in the valley, one to the north, one to the east and one to the southwest. The profiles cross the Las Vegas Valley Shear zone as well as a prominent

  18. Identification of Porphyromonas gingivalis proteins secreted by the Por secretion system.

    PubMed

    Sato, Keiko; Yukitake, Hideharu; Narita, Yuka; Shoji, Mikio; Naito, Mariko; Nakayama, Koji

    2013-01-01

    The Gram-negative bacterium Porphyromonas gingivalis possesses a number of potential virulence factors for periodontopathogenicity. In particular, cysteine proteinases named gingipains are of interest given their abilities to degrade host proteins and process other virulence factors such as fimbriae. Gingipains are translocated on the cell surface or into the extracellular milieu by the Por secretion system (PorSS), which consists of a number of membrane or periplasmic proteins including PorK, PorL, PorM, PorN, PorO, PorP, PorQ, PorT, PorU, PorV (PG27, LptO), PorW and Sov. To identify proteins other than gingipains secreted by the PorSS, we compared the proteomes of P. gingivalis strains kgp rgpA rgpB (PorSS-proficient strain) and kgp rgpA rgpB porK (PorSS-deficient strain) using two-dimensional gel electrophoresis and peptide-mass fingerprinting. Sixteen spots representing 10 different proteins were present in the particle-free culture supernatant of the PorSS-proficient strain but were absent or faint in that of the PorSS-deficient strain. These identified proteins possessed the C-terminal domains (CTDs), which had been suggested to form the CTD protein family. These results indicate that the PorSS is used for secretion of a number of proteins other than gingipains and that the CTDs of the proteins are associated with the PorSS-dependent secretion. PMID:23075153

  19. System design description for portable 1,000 CFM exhauster Skids POR-007/Skid E and POR-008/Skid F

    SciTech Connect

    Nelson, O.D.

    1998-07-25

    The primary purpose of the two 1,000 CFM Exhauster Skids, POR-007-SKID E and POR-008-SKID F, is to provide backup to the waste tank primary ventilation systems for tanks 241-C-106 and 241-AY-102, and the AY-102 annulus in the event of a failure during the sluicing of tank 241-C-106 and subsequent transfer of sluiced waste to 241-AY-102. This redundancy is required since both of the tank ventilation systems have been declared as Safety Class systems.

  20. Centros oncológicos designados por el NCI

    Cancer.gov

    El programa de centros oncológicos designados por el Instituto Nacional del Cáncer (NCI) reconoce a los centros de todo el país que cumplen con rigurosos criterios para participar en proyectos avanzados de primer nivel para la investigación multidisciplinaria del cáncer.

  1. [Las Cruces Bilingual Education Project, Evaluation Report: 1969-70.

    ERIC Educational Resources Information Center

    Las Cruces School District, NM.

    The Las Cruces Elementary School Bilingual Program, designed to increase achievement levels of K-6 pupils, is located in 2 elementary schools through support from titles III and VII of the Elementary and Secondary Education Act. The project emphasizes the cultural and linguistic heritage of the Las Cruces, New Mexico, area; the structure of the…

  2. Tabla de Especificaciones e Instructivo sobre Elaboracion de Pruebas Objetivas en la Ensenanza Primaria, para las asignaturas de Estudios Sociales, Idioma Espanol, Matematicas y Ciencias Naturales (Specification Tables and Instructions for the Construction of Objective Tests in the Primary Grades in Social Studies, Spanish, Mathematics, and Natural Sciences).

    ERIC Educational Resources Information Center

    Ministerio de Educacion, Guatemala City (Guatemala). Direccion de Bienestar Estudiantil y Educacion Especial.

    This booklet presents specification tables illustrating the relative importance given to topics on tests within a particular subject area. The general subject areas are social studies, Spanish, mathematics, and natural sciences. Tables are provided for final exams in each of these areas for several primary grades, illustrating the importance of…

  3. Perspectivas para mejorar la salud sexual de las minorías sexuales y de identidad de género en Guatemala

    PubMed Central

    Alonzo, Jorge; Mann, Lilli; Simán, Florence; Sun, Christina J.; Andrade, Mario; Villatoro, Guillermo; Rhodes, Scott D.

    2016-01-01

    Resumen Las minorías sexuales y de identidad de género en Guatemala son afectadas de manera desproporcionada por el VIH y otras infecciones transmitidas sexualmente (ITS). Sin embargo, poco se sabe de los factores que contribuyen al riesgo de infección en estas minorías. Investigadores de Estados Unidos y Guatemala quisimos informarnos sobre las necesidades de salud sexual e identificar características de programas de prevención de VIH/ITS para estas minorías. Llevamos a cabo 8 grupos focales con hombres gay, bisexuales y personas transgénero y entrevistas en profundidad con líderes comunitarios. Utilizamos el Método Comparativo Constante para analizar las transcripciones. Identificamos 24 factores que influyen en la salud sexual y 16 características de programas para reducir el riesgo de VIH/ITS en estas poblaciones. La identificación de factores de conductas sexuales de riesgo y de características de programas potencialmente efectivos ofrece gran potencial para desarrollar intervenciones que contribuyan a reducir el riesgo de infección por VIH/ITS en estas minorías en Guatemala. PMID:27494000

  4. LAS - LAND ANALYSIS SYSTEM, VERSION 5.0

    NASA Technical Reports Server (NTRS)

    Pease, P. B.

    1994-01-01

    The Land Analysis System (LAS) is an image analysis system designed to manipulate and analyze digital data in raster format and provide the user with a wide spectrum of functions and statistical tools for analysis. LAS offers these features under VMS with optional image display capabilities for IVAS and other display devices as well as the X-Windows environment. LAS provides a flexible framework for algorithm development as well as for the processing and analysis of image data. Users may choose between mouse-driven commands or the traditional command line input mode. LAS functions include supervised and unsupervised image classification, film product generation, geometric registration, image repair, radiometric correction and image statistical analysis. Data files accepted by LAS include formats such as Multi-Spectral Scanner (MSS), Thematic Mapper (TM) and Advanced Very High Resolution Radiometer (AVHRR). The enhanced geometric registration package now includes both image to image and map to map transformations. The over 200 LAS functions fall into image processing scenario categories which include: arithmetic and logical functions, data transformations, fourier transforms, geometric registration, hard copy output, image restoration, intensity transformation, multispectral and statistical analysis, file transfer, tape profiling and file management among others. Internal improvements to the LAS code have eliminated the VAX VMS dependencies and improved overall system performance. The maximum LAS image size has been increased to 20,000 lines by 20,000 samples with a maximum of 256 bands per image. The catalog management system used in earlier versions of LAS has been replaced by a more streamlined and maintenance-free method of file management. This system is not dependent on VAX/VMS and relies on file naming conventions alone to allow the use of identical LAS file names on different operating systems. While the LAS code has been improved, the original capabilities

  5. Radioxenon Atmospheric Measurements in North Las Vegas

    SciTech Connect

    Milbrath, Brian D.; Cooper, Matthew W.; Lidey, Lance S.; Bowyer, Ted W.; Hayes, James C.; McIntyre, Justin I.; Karr, L.; Shafer, David S.; Tappen, J.

    2007-09-25

    Pacific Northwest National Laboratory (PNNL) deployed the Automated Radioxenon Sampler/Analyzer (ARSA) in North Las Vegas for two weeks in February and March 2006 for the purpose of measuring the radioxenon background at a level of sensitivity much higher than previously done in the vicinity of the Nevada Test Site (NTS). The measurements establish what might be expected if future measurements are taken at NTS itself and investigate improved methods of environmental monitoring of NTS for test site readiness. Also, such radioxenon measurements have not previously been performed in a United States location considered to be as remote from nuclear reactors. A second detector, the Portable Environmental Monitoring Station (PEMS), built and operated by the Desert Research Institute (DRI), was deployed in conjunction with the ARSA and contained a pressure ion chamber, aerosol collection filters, and meteorological sensors. Some of the radioxenon measurements detected 133Xe at levels up to 3 mBq/m3. This concentration of radioxenon is consistent with the observation of low levels of radioxenon emanating from distance nuclear reactors. Previous measurements in areas of high nuclear reactor concentration have shown similar results, but the western US, in general, does not have many nuclear reactors. Measurements of the wind direction indicate that the air carrying the radioxenon came from south of the detector and not from the NTS.

  6. Se evitaron casi 800 000 muertes por descenso del tabaquismo

    Cancer.gov

    Programas y estrategias de control del tabaco del siglo XX fueron responsables de la prevención de más de 795 000 muertes por cáncer de pulmón en Estados Unidos de 1975 al 2000. Si todo el tabaquismo en este país hubiera cesado después de la publicación d

  7. Estudio comparativo de las moléculas isovalentes de interés atmosférico CF3Cl y CF3Br y sus correspondientes halógenos aislados Cl y Br.

    NASA Astrophysics Data System (ADS)

    Mayor, E.; Velasco, A. M.; Martín, I.; Lavín, C.

    Los estados Rydberg moleculares han suscitado en los últimos años un creciente interés entre los espectroscopistas experimentales, motivado en parte por el desarrollo de nuevas técnicas espectroscópicas capaces de investigar estos estados altamente excitados electrónicamente. Los procesos de fotoabsorción que implican estados Rydberg en los derivados halogenados del metano son de gran importancia, debido a su abundancia en la atmósfera y a sus implicaciones medioambientales. Por ello, la obtención de datos relativos a sus fuerzas de oscilador es de gran interés. En este trabajo se aborda el estudio de dichas propiedades para las moléculas isovalentes CF3Cl y CF3Br. Ambas moléculas presentan idéntica estructura electrónica para el estado fundamental por lo que se espera que sus espectros Rydberg presenten grandes similitudes, en ausencia de perturbaciones. Por ello y dada la escasez de datos relativos a fuerzas de oscilador, hemos establecido la corrección de nuestros resultados en base a las analogías esperadas en las intensidades espectrales correspondientes a transiciones análogas. Por otro lado, Novak y col. [1] han encontrado experimentalmente un marcado carácter atómico en el espectro correspondiente a estas moléculas, siendo muy similar a los de los átomos de Cl y Br. Por ello en el presente trabajo, además de establecer la comparación entre ambas moléculas hemos buscado las similitudes con sus respectivos halógenos. Los cálculos relativos a las especies moleculares se han realizado utilizando la Metodología Molécular de Orbítales de Defecto Cuántico (MQDO) [2], mientras que para el estudio de los átomos de Cl y Br se empleó la versión relativista del método (RQDO) [3].

  8. DISYUNTIVAS EN LAS CONCEPCIONES SOBRE AUTONOMÍA Y BENEFICENCIA QUE AFECTAN LA TERAPÉUTICA DEL INTENTO SUICIDA1

    PubMed Central

    Mondragón, Liliana; Monroy, Zuraya; Ito, Ma. Emily; Medina-Mora, Dra. Ma. Elena

    2010-01-01

    El objetivo del trabajo es conocer las disyuntivas entre los principios de beneficencia y autonomía, que se presentan en la relación médico-paciente, durante la terapéutica del intento de suicidio. La investigación se realizó en dos hospitales psiquiátricos de la Ciudad de México. La muestra incluyó a tres sujetos con intento de suicidio, mayores de 18 años, que eran atendidos en consulta externa a causa de una lesión autoinfligida en el último año, y a tres psiquiatras que trataban a estos pacientes. La información se obtuvo previo consentimiento informado en entrevistas individuales. Se llevó a cabo un análisis de discurso argumentado para encontrar los significados que los participantes otorgaron a los principios bioéticos y las posibles disyuntivas entre éstos. Las discordancias entre la beneficencia y la autonomía estuvieron relacionadas con el beneficio del tratamiento, el respeto por los valores y las creencias de los pacientes, entre otros. Este trabajo presenta consideraciones éticas relevantes en el escenario clínico, al ofrecer al psiquiatra un análisis bioético que le permita actuar de acuerdo con la beneficencia y respetando la autonomía del paciente frente a casos de intento de suicidio y, de esta forma procurar una mejor atención para ellos. PMID:20830214

  9. The Land Analysis System (LAS) for multispectral image processing

    USGS Publications Warehouse

    Wharton, S. W.; Lu, Y. C.; Quirk, Bruce K.; Oleson, Lyndon R.; Newcomer, J. A.; Irani, Frederick M.

    1988-01-01

    The Land Analysis System (LAS) is an interactive software system available in the public domain for the analysis, display, and management of multispectral and other digital image data. LAS provides over 240 applications functions and utilities, a flexible user interface, complete online and hard-copy documentation, extensive image-data file management, reformatting, conversion utilities, and high-level device independent access to image display hardware. The authors summarize the capabilities of the current release of LAS (version 4.0) and discuss plans for future development. Particular emphasis is given to the issue of system portability and the importance of removing and/or isolating hardware and software dependencies.

  10. Pincharse sin infectarse: estrategias para prevenir la infección por el VIH y el VHC entre usuarios de drogas inyectables

    PubMed Central

    MATEU-GELABERT, P.; FRIEDMAN, S.; SANDOVAL, M.

    2011-01-01

    Resumen Objetivo Desde principios de los noventa, en la ciudad de Nueva York se han implementado con éxito programas para reducir la incidencia del virus de la inmunodeficiencia humana (VIH) y, en menor medida, del virus de la hepatitis C (VHC). A pesar de ello, aproximadamente el 70% de los usuario de drogas inyectables (UDI) están infectados por el VHC. Queremos investigar cómo el 30% restante se las ha arreglado para no infectarse. El Staying safe (nombre original del estudio) explora los comportamientos y mecanismos que ayudan a evitar la infección por el VHC y el VIH a largo plazo. Material y métodos Hemos utilizado el concepto de «desviación positiva» aplicado en otros campos de salud pública. Estudiamos las estrategias, prácticas y tácticas de prevención de aquellos UDI que, viviendo en contextos de alta prevalencia, se mantienen sin infectar por VIH y el VHC, a pesar de haberse inyectado heroína durante años. Los resultados preliminares presentados en este artículo incluyen el análisis de las entrevistas realizadas a 25 UDI (17 doble negativos, 3 doble positivos y 5 con infección por el VHC y sin infección por el VIH). Se usaron entrevistas semiestructuradas que exploraban con detalle la historia de vida de los sujetos, incluyendo su consumo de drogas, redes sociales, contacto con instituciones, relaciones sexuales y estrategias de protección y vigilancia. Resultados La intencionalidad es importante para no infectarse, especialmente durante períodos de involución (períodos donde hay un deterioro económico y/o social que llevan al que se inyecta a situaciones de mayor riesgo). Presentamos tres dimensiones independientes de intencionalidad que conllevan comportamientos que pueden ayudar a prevenir la infección: a) evitar «el mono» (síntomas de abstención) asegurando el acceso a la droga; b) «llevarlo bien» para no convertirse en un junkie y así evitar la «muerte social» y la falta de acceso a los recursos, y c) seguir sin

  11. Actitudes de los candidatos y maestros de ciencias en servicio acerca del uso de las herramientas computadorizadas en las clases de ciencias

    NASA Astrophysics Data System (ADS)

    Bayuelo, Ezequiel

    Este estudio examino y comparo las actitudes de los candidatos a maestros de ciencias y los maestros de ciencias en servicio acerca de la utilizacion de las herramientas computadorizadas en las clases de ciencias. Tambien identifico y diferencio el uso que ellos dan a estas herramientas en las clases de ciencias. Este estudio presenta un diseno descriptivo exploratorio. Constituyeron la muestra trescientos diez sujetos que fueron candidatos a maestros de ciencias o maestros de ciencias en servicio. Para recoger los datos se construyo y valido un cuestionario de treinta y un itemes. Se utilizaron las pruebas estadisticas no parametricas Kruskal Wallis y Chi-cuadrado (test de homogeneidad) para establecer las diferencias entre las actitudes de los sujetos con relacion al uso de las herramientas computadorizadas en las clases de ciencias. Los hallazgos evidenciaron que son positivas y muy parecidas las actitudes de los candidatos a maestros y maestros en servicio hacia el uso de las herramientas computadorizadas. No hubo diferencias entre los candidatos y maestros en servicio en terminos de las actitudes de confianza y empatia hacia el uso de las herramientas computadorizadas en las clases de ciencias. En aspectos como el uso del banco de datos bibliografico Eric y el uso de las herramientas computadorizadas en actividades educativas como explorar conceptos, conceptuar, aplicar lo aprendido y hacer asignaciones hubo diferencias estadisticamente significativas entre los candidatos y los maestros en servicio. Al comparar las frecuencias observadas con las esperadas hubo mas maestros en servicio y menos candidatos que indicaron usar el anterior banco de datos y las herramientas computadorizadas en las mencionadas actividades educativas.

  12. Que hay de nuevo acerca de la inmersion? Un Breve Recorrido por sus Fundamentos y por las Investigaciones Actuales (What's New in Immersion? A Brief Overview of Its Bases and Present-Day Research).

    ERIC Educational Resources Information Center

    Sierra, Josu

    This discussion briefly surveys the development of the immersion method of second language teaching, outlining the central program strategies and characteristics using Curtain's and Pesola's descriptions. An overview of recent research focuses on error correction and feedback studies as an example of pedagogical-methodological evolution in this…

  13. Neisseria meningitidis Lacking the Major Porins PorA and PorB Is Viable and Modulates Apoptosis and the Oxidative Burst of Neutrophils.

    PubMed

    Peak, Ian R; Chen, Adrienne; Jen, Freda E-C; Jennings, Courtney; Schulz, Benjamin L; Saunders, Nigel J; Khan, Arshad; Seifert, H Steven; Jennings, Michael P

    2016-08-01

    The bacterial pathogen Neisseria meningitidis expresses two major outer-membrane porins. PorA expression is subject to phase-variation (high frequency, random, on-off switching), and both PorA and PorB are antigenically variable between strains. PorA expression is variable and not correlated with meningococcal colonisation or invasive disease, whereas all naturally-occurring strains express PorB suggesting strong selection for expression. We have generated N. meningitidis strains lacking expression of both major porins, demonstrating that they are dispensable for bacterial growth in vitro. The porAB mutant strain has an exponential growth rate similar to the parental strain, as do the single porA or porB mutants, but the porAB mutant strain does not reach the same cell density in stationary phase. Proteomic analysis suggests that the double mutant strain exhibits compensatory expression changes in proteins associated with cellular redox state, energy/nutrient metabolism, and membrane stability. On solid media, there is obvious growth impairment that is rescued by addition of blood or serum from mammalian species, particularly heme. These porin mutants are not impaired in their capacity to inhibit both staurosporine-induced apoptosis and a phorbol 12-myristate 13-acetate-induced oxidative burst in human neutrophils suggesting that the porins are not the only bacterial factors that can modulate these processes in host cells. PMID:26562068

  14. Regiones de formación de estrellas masivas en las Nubes de Magallanes

    NASA Astrophysics Data System (ADS)

    Barbá, R.; Maíz Apellániz, J.; Rubio, M.; Walborn, N.

    Las Nubes de Magallanes son un laboratorio formidable para el estudio de regiones de formación estelar. A diferencia de lo que sucede en el plano galáctico, ambas galaxias contienen poco polvo que nos afecte la visión directa de dichas regiones. Por otra parte, la menor metalicidad de las Nubes, nos permiten hacer un estudio comparativo de la formación estelar en ambientes de baja metalicidad. El presente trabajo da una revisión de los progresos notables que hemos alcanzado en el conocimiento del contenido estelar de algunas regiones de formación de estrellas masivas en ambas Nubes, en base a la utilización de imágenes del Telescopio Espacial Hubble, Gemini Sur, y Very Large Telescope, entre otros. En especial, nos concentramos en 30 Doradus y N11 en la Nube Mayor, y en NGC 346 en la Nube Menor. Nuevas imágenes de N11 obtenidas en los últimos meses con la Advanced Camera for Surveys del Hubble (óptico), y con Flamingos en Gemini Sur (infrarrojo), nos han permitido descubrir un nuevo `jet' con origen en una fuente infrarroja sumergida en un pilar polvoriento similar al objeto Herbig-Haro de M20 en nuestra galaxia. Este `jet' (junto a otros tres que hemos descubierto en 30 Doradus), es el cuarto ejemplo confirmado de `jet' asociado a una protoestrella fuera de nuestra galaxia. Además, presentamos el descubrimiento del primer objeto estelar joven masivo de la Nube Menor confirmado espectroscópicamente.

  15. Precisión de las velocidades radiales obtenidas con el REOSC

    NASA Astrophysics Data System (ADS)

    González, J. F.; Lapasset, E.

    Complementando una línea de trabajo iniciada con anterioridad discutimos la estabilidad del espectrógrafo REOSC de CASLEO en DC para la medición de velocidades radiales en base al análisis de observaciones realizadas en enero y abril de 1997. En esas oportunidades obtuvimos 26 espectros de estrellas patrones y 27 espectros de 3 estrellas usadas como estrellas de referencia en nuestro programa de cúmulos abiertos. Además tomamos 26 espectros de crepúsculo con el telescopio en posiciones cubriendo el rango H=-4,+4 y δ =-90,+30. Mediante correlaciones cruzadas derivamos la velocidad de 19 órdenes en cada uno de estos espectros. En base a un análisis estadístico de los datos obtenidos discutimos la contribución de los distintos factores que afectan a la dispersión de lectura observada. En particular, la flexión del instrumento no introduciría errores significativos cuando se observa con masas de aire menores que 2.0. La dispersión de los valores de velocidad medidos para espectros de alta relación S/N de una misma estrella resultó del orden de 0.5 km/s. La comparación con los valores de velocidad publicados por distintos autores para las estrellas patrones no permite distinguir ninguna diferencia sistemática apreciable de las velocidades de CASLEO, siendo la media cuadrática de los residuos del orden de 1.0 km/s.

  16. La inserción en el mercado laboral de los inmigrantes latinos en España y en los Estados Unidos: Diferencias por país de origen y estatus legal

    PubMed Central

    Connor, Phillip; Massey, Douglas

    2013-01-01

    Resumen Este artículo compara los resultados económicos entre los inmigrantes latinoamericanos en España y Estados Unidos. Detectamos un efecto de selección por el que la mayoría de los inmigrantes latinoamericanos en España proceden de Sudamérica de un entorno de clases medias, mientras la mayoría de los inmigrantes que van a los Estados Unidos son centroamericanos de clase baja. Este efecto de selección explica las diferencias transnacionales en la probabilidad de empleo, logro ocupacional y salarios obtenidos. A pesar de las diferencias en los orígenes y las características de los latinoamericanos en ambos países, los factores demográficos, humanos y de capital social parecen operar de forma similar en ambos países; y cuando los modelos se estiman separadamente por estatus legal, descubrimos que los efectos se acentúan más entre los inmigrantes irregulares cuando se los compara con los regulares, especialmente en Estados Unidos. PMID:24532857

  17. Wintertime aerosol in Las Vegas, Nevada

    NASA Astrophysics Data System (ADS)

    Brown, Steven G.

    Numerous studies have found adverse health effects in subjects who live next to major roadways due to air pollution; in particular, there can be severe impacts on lung function and development in children living and/or attending school next to major roadways due to their exposure to air pollutants, including particulate matter (PM) or aerosol. The composition of aerosol at an elementary school next to a major freeway in Las Vegas, Nevada during winter 2008 was measured using a suite of measurements. An Aerodyne High Resolution Aerosol Mass Spectrometer (HR-AMS) was used to quantify the composition of non-refractory PM1 aerosol, including organic matter (OM); an Aethalometer was used to quantify black carbon (BC); a Sunset OCEC analyzer was used to measure organic and elemental carbon (OC, EC); and a particle-into-liquid system (PILS) coupled to two ion chromatographs (IC) was used to measure fine particle ions. Hi-volume PM2.5 samplers were used to collect aerosol on quartz fiber filters at between 2 and 24 hour intervals during the study, a subset of which were analyzed for PAHs and the biomass burning tracer levoglucosan. Data were analyzed by positive matrix factorization (PMF) to determine the amount of fresh, hydrocarbon-like organic aerosol (HOA), more oxidized OA (low-volatility and semi-volatile OA [LV-OOA, SV-OOA]) and biomass burning OA (BBOA). PM1 aerosol was predominantly carbonaceous, with OM plus BC accounting for 74% of the overall average 6.9 mug/m3 of PM measured. BC had a diurnal pattern similar to traffic volume, while OM was higher in the evening compared to the morning. OM was a mixture of fresh HOA, urban- and regional-scale OOA, and BBOA; in the evening, SV-OOA and BBOA peaked, while HOA concentrations were on average the same in the morning and evening, similar to BC. OM/OC ratios were low (1.52 +/-0.14 on average) during the morning rush hour (average OM = 2.4 mug/m3) when vehicular emissions dominate this near-road measurement site, and

  18. Efectos de Campos Magnéticos en las Tasas de Consumo de Madera por Coptotermes formosanus, la Termita Subterránea de Formosa.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sixty groups of 500 workers and 50 soldiers of Coptotermes formosanus were maintained in costume designed containers and fed with a piece of red oak wood (Quercus rubra). Twenty of these groups were exposed to permanent magnets with a flux of 800 G. Another 20 groups were exposed to a permanent mag...

  19. Compton imaging with the PorGamRays spectrometer

    NASA Astrophysics Data System (ADS)

    Judson, D. S.; Boston, A. J.; Coleman-Smith, P. J.; Cullen, D. M.; Hardie, A.; Harkness, L. J.; Jones, L. L.; Jones, M.; Lazarus, I.; Nolan, P. J.; Pucknell, V.; Rigby, S. V.; Seller, P.; Scraggs, D. P.; Simpson, J.; Slee, M.; Sweeney, A.; PorGamRays Collaboration

    2011-10-01

    The PorGamRays project aims to develop a portable gamma-ray detection system with both spectroscopic and imaging capabilities. The system is designed around a stack of thin Cadmium Zinc Telluride (CZT) detectors. The imaging capability utilises the Compton camera principle. Each detector is segmented into 100 pixels which are read out through custom designed Application Specific Integrated Circuits (ASICs). This device has potential applications in the security, decommissioning and medical fields. This work focuses on the near-field imaging performance of a lab-based demonstrator consisting of two pixelated CZT detectors, each of which is bonded to a NUCAM II ASIC. Measurements have been made with point 133Ba and 57Co sources located ˜35 mm from the surface of the scattering detector. Position resolution of ˜20 mm FWHM in the x and y planes is demonstrated.

  20. Acceptance test report for portable exhauster POR-007/Skid E

    SciTech Connect

    Kriskovich, J.R.

    1998-07-24

    This document describes Acceptance Testing performed on Portable Exhauster POR-007/Skid E. It includes measurements of bearing vibration levels, pressure decay testing, programmable logic controller interlocks, high vacuum, flow and pressure control functional testing. The purpose of Acceptance testing documented by this report was to demonstrate compliance of the exhausters with the performance criteria established within HNF-0490, Rev. 1 following a repair and upgrade effort at Hanford. In addition, data obtained during this testing is required for the resolution of outstanding Non-conformance Reports (NCR), and finally, to demonstrate the functionality of the associated software for the pressure control and high vacuum exhauster operating modes provided for by W-320. Additional testing not required by the ATP was also performed to assist in the disposition and close out of receiving inspection report and for application design information (system curve). Results of this testing are also captured within this document.

  1. Nuevos escenarios de la migración México-Estados Unidos. Las consecuencias de la guerra antiinmigrante

    PubMed Central

    MASSEY, Douglas S.; PREN, Karen A.; DURAND, Jorge

    2010-01-01

    La historia de la migración México-Estados Unidos se caracteriza por una serie de periodos durante los cuales los patrones migratorios se transforman y evolucionan como respuesta a los cambios en la política migratoria de Estados Unidos. En la década de 1990 se dio uno de estos cambios, lo que provocó el paso de la ‘era de la contradicción’ a la ‘era de la marginalización’. Actualmente, un gran número de migrantes indocumentados permanecen al margen de la ley, precisamente en un periodo en el que las penas se han incrementado y la persecución ha alcanzado niveles récord. De manera cada vez más notoria, los migrantes indocumentados, por la represión interna y fronteriza, quedan obligados a romper los lazos que los vinculaban con sus lugares de destino, pero al mismo tiempo se sienten cada vez más extraños en una tierra donde la aplicación de políticas antiinmigrantes es cosa de todos los días, lo que los sitúa en una posición de marginalización y gran vulnerabilidad. PMID:21209790

  2. Analysis of the Pseudomonas aeruginosa elastase (lasB) regulatory region.

    PubMed Central

    Rust, L; Pesci, E C; Iglewski, B H

    1996-01-01

    The enzyme elastase is an important virulence factor of the opportunistic human pathogen Pseudomonas aeruginosa. Previous studies have shown that expression of the P. aeruginosa elastase gene (lasB) requires both an activator protein, LasR, and an N-acylhomoserine lactone compound termed Pseudomonas autoinducer (PAI). In this study, we analyzed the lasB promoter region to learn more about lasB activation by LasR and PAI. We report that the lasB transcriptional start is located 141 nucleotides upstream from the lasB translational start. It was also discovered that the lasB promoter region contains two putative operator sequences (OP1 and OP2) that are similar to each other and the Vibrio fischeri lux operator. OP1 is located directly upstream from, and may overlap with, the lasB promoter region, and OP2 is centered 102 nucleotides upstream from the lasB transcriptional start site. To study the effects of these putative operators and other sequences upstream from the lasB transcriptional start site on lasB activation, a series of transcriptional lasBp-lacZ gene fusions was constructed. Data from these fusions indicate that both putative operators are involved in LasR- and PAI-mediated lasB activation, with OP1 being more important than OP2. PMID:8576049

  3. Typing and surface charges of the variable loop regions of PorB from Neisseria meningitidis.

    PubMed

    Stefanelli, Paola; Neri, Arianna; Tanabe, Mikio; Fazio, Cecilia; Massari, Paola

    2016-06-01

    PorB is a pan-Neisserial major outer membrane protein with a trimeric β-barrel structure. Each monomer presents eight periplasmic turns and eight surface exposed loop regions with sequence variability. PorB induces activation of host cell responses via a TLR2-dependent mechanism likely mediated by electrostatic interactions between TLR2 and PorB surface exposed loops. Variability in the loop amino acid sequence is known to influence cell responses to PorB in vitro, particularly for the residues in L5 and L7. In this work, the sequence of the porB gene and the electrostatic surface charges of PorB from 35 invasive meningococcal isolates belonging to the main clonal complexes identified in Italy and from five carriage genomes available on the website http://pubmlst.org/neisseria/ were examined. Analysis of the porB encoding regions from the invasive meningococci has identified four new alleles and a potential association between porB alleles, serogroup, and clonal complexes. Through computer-based modeling and analysis of the electrostatic surface charges of PorB from these strains, loop charge segregation between PorB from invasive serogroups B and C was observed. Specifically, loops 1, 4, and 7 were negatively charged and L2 and L8 were mostly neutral in serogroup B isolates, while an overall homogeneous positive surface charge was present in PorB from invasive serogroup C strains. A higher PorB sequence variability was observed among carriage genomes, and a general prevalence of negative loop surface charges. The surface charge differences in PorB from serogroups B and C invasive and carriage strains may, in part, influence the outcomes of Neisseriae interactions with host cells. © 2016 IUBMB Life, 68(6):488-495, 2016. PMID:27156582

  4. Male courtship behavior in Ceratitis Capitata (Diptera: Tephritidae) that have received Aromatherapy with ginger root oil

    SciTech Connect

    Briceno, D.; Eberhard, W.; Shelly, T.

    2007-03-15

    The results of previous studies that showed that exposing mass-reared male Mediterranean fruit flies Ceratitis capitata (Wiedemann) to ginger root oil ('aromatherapy') increases the likelihood of mating with wild females were confirmed. The increased male success could be due to female responses to changes in male behavior or male pheromones. There were no significant differences in the types of courtship movements executed by males with and without aromatherapy. The durations of movements also did not differ when mass-reared males were paired with mass-reared females; however, when they were paired with wild females, there were a few, small differences. Previous studies indicated that the effectiveness of the male long-distance attractant pheromone is not affected by aromatherapy, but these studies did not consider pheromones released at close range during courtship, which behavioral analyses suggest may be different. We propose the following possible explanation for the different effects of aromatherapy with different females. Selection on males under mass rearing may have altered their close-range pheromones in ways that can be remedied by aromatherapy; and only wild females respond because the pheromonal responsiveness of mass-reared females has also changed. We propose observations that could test these ideas. (author) [Spanish] Los resultados de estudios previos que muestran que al exponer machos criados en masa de la mosca mediterranea de la fruta Ceratitis capitata (Wiedemann) al aceite de la raiz del jengibre ('aromaterapia') aumento la probabilidad del apareamiento con hembras naturales fueron confirmados. El aumento en el exito de los machos puede ser debido a las respuestas de las hembras a los cambios en el comportamiento o feromonas de los machos. No hubo una diferencia significativa en la clase de los movimientos del cortejo ejecutados por los machos con y sin la aromaterapia. La duracion de los movimientos tampoco fue diferente cuando los machos

  5. Different Cultures in Astronomy Education and Their Meanings in the Classroom. (Spanish Title: Las Diferentes Culturas en la Educación en Astronomía y Sus Significados EN EL Aula. ) As Diferentes Culturas na Educação em Astronomia E Seus Significados em Sala de Aula

    NASA Astrophysics Data System (ADS)

    Pereira de Barros, Vicente; Bovolenta Ovigli, Daniel Fernando

    2014-12-01

    This paper is a reflection about the use of History of Science in the curriculum of formal education, through the discussion concerning cultural elements of several ethnic groups in Brazil, in actions related to astronomy education. The work was developed in the framework of an extension course and the analysis undertaken here refers to a meeting that discussed didactic sequences relating to that theme, based on the Brazilian law 11.645/2008, which states the obligation to present the subject "African-brazilian and indigenous History and Culture" in the official curriculum. The extension action was developed with teachers who teach Natural Sciences, in São Paulo state, discussing issues related to the use of History of Science and the relationship with cosmogonies from Iorubá and Tupi peoples, highlighting how they can enhance the work with Astronomy(ies) in the classroom. It was observed that the participants had not yet presented these themes in their classes and also did not participate in training courses that discussed these subjects. Este artículo presenta una reflexión sobre el uso de la historia de la ciencia en el currículo de la educación formal, a través de la discusión sobre el uso de los elementos culturales de los grupos étnicos en Brasil, en acciones relacionadas con la educación en astronomía. El trabajo se desarrolló en el marco de un curso de extensión y el análisis realizado aquí se refiere a un encuentro en el cual se abordaron secuencias didácticas relacionadas con ese tema, sobre la base de la ley brasilera 11.645/2008 que dispone la obligatoriedad del tema "Historia y Cultura africana e indígena en el Brasil" en el currículo oficial. La acción de extensión se desarrolló con los profesores de ciencias naturales en el interior del estado de São Paulo, discutiendo temas relacionados con el uso de la historia de la ciencia y la relación con las cosmogonías de los pueblos Iorubá y Tupi, que muestra cómo se puede mejorar

  6. The Las Vegas Sustainability Atlas: Modeling Place-based Interactions and Implications in the Las Vegas Valley Bioregion

    NASA Astrophysics Data System (ADS)

    Ego, H.; McCown, K.; Saghafi, N.; Gross, E.; Hunter, W.; Zawarus, P.; Gann, A.; Piechota, T. C.

    2014-12-01

    Las Vegas, Nevada, with 2 million residents and 40 million annual visitors, is one of the driest metropolitan environments of its size in the world. The metro imports nearly all of its resources, including energy, water and food. Rapid population increases, drought, and temperature increases due to climate change create challenges for planning resilient systems in the Las Vegas Valley. Because of its growth rate, aridity, Las Vegas, Nevada is a significant and relevant region for the study of the water, energy, food and climate nexus. Cities in the United States and the world are seeing increasing trends in urbanization and water scarcity. How does the water-energy-climate-food nexus affect each metropolitan area? How can this complex information be used for resiliency planning? How can it be related to the public, so they can understand the issues in a way that makes them meaningful participants in the planning process? The topic of our presentation is a 'resiliency atlas.' The atlas is a place-based model tested in Las Vegas to explore bioregional distinctiveness of the water-energy-climate-food nexus, including regional transportation systems. The atlas integrates the systems within a utilitarian organization of information. Systems in this place-based model demonstrate how infrastructure services are efficiently provided for the Las Vegas Valley population. This resiliency atlas can clarify how the nexus applies to place; and how it can be used to spur geographically germane adaption strategies. In the Las Vegas Valley, climate change (drought and high sustained temperatures) and population affect water, energy, and food systems. This clarity of a place based model can help educate the public about the resilience of their place, and facilitate and organize the planning process in the face of uncertainty.

  7. Las Rocas Nos Cuentan (Rocks Tell Their Stories)

    ERIC Educational Resources Information Center

    Llerandi-Roman, Pablo A.

    2012-01-01

    Many Earth science lessons today still focus on memorizing the names of rocks and minerals. This led the author to develop a lesson that reveals the fascinating stories told by rocks through the study of their physical properties. He first designed the lesson for Puerto Rican teachers, hence its Spanish title: "Las Rocas Nos Cuentan Su Historia."…

  8. Child and Family Resource Program (Las Vegas, Nevada). Program Description.

    ERIC Educational Resources Information Center

    Development Associates, Inc., Washington, DC.

    An infant-toddler program of parent training in child growth and development, based primarily in the home, has become the major focus of the Child and Family Resource Program (EFRP) in Las Vegas, Nevada, one of 11 sites in this Head Start affiliated program. This report describes and evaluates: (1) the goals and operational objectives of the…

  9. Acceptance test report for portable exhauster POR-008/Skid F

    SciTech Connect

    Kriskovich, J.R.

    1998-07-24

    Portable Exhauster POR-008 was procured via HNF-0490, Specification for a Portable Exhausted System for Waste Tank Ventilation. Prior to taking ownership, acceptance testing was performed at the vendors. However at the conclusion of testing a number of issues remained that required resolution before the exhausters could be used by Project W-320. The purpose of acceptance testing documented by this report was to demonstrate compliance of the exhausters with the performance criteria established within HNF-O49O, Rev. 1 following a repair and upgrade effort at Hanford. In addition, data obtained during this testing is required for the resolution of outstanding Non-conformance Reports (NCR), and finally, to demonstrate the functionality of the associated software for the pressure control and high vacuum exhauster operating modes provided for by W-320. Additional testing not required by the ATP was also performed to assist in the disposition and close out of receiving inspection report and for application design information (system curve). Results of this testing are also captured within this document.

  10. Neuropatía periférica inducida por quimioterapia

    Cancer.gov

    Artículo sobre un efecto secundario de la quimioterapia que causa dolor y malestar en las manos y los pies. También incluye información sobre los esfuerzos para mejorar las opciones de detección, tratamiento y prevención.

  11. VDAC and the bacterial porin PorB of Neisseria gonorrhoeae share mitochondrial import pathways.

    PubMed

    Müller, Anne; Rassow, Joachim; Grimm, Jan; Machuy, Nikolaus; Meyer, Thomas F; Rudel, Thomas

    2002-04-15

    The human pathogen Neisseria gonorrhoeae induces host cell apoptosis during infection by delivering the outer membrane protein PorB to the host cell's mitochondria. PorB is a pore-forming beta-barrel protein sharing several features with the mitochondrial voltage-dependent anion channel (VDAC), which is involved in the regulation of apoptosis. Here we show that PorB of pathogenic Neisseria species produced by host cells is efficiently targeted to mitochondria. Imported PorB resides in the mitochondrial outer membrane and forms multimers with similar sizes as in the outer bacterial membrane. The mitochondria completely lose their membrane potential, a characteristic previously observed in cells infected with gonococci or treated with purified PorB. Closely related bacterial porins of non-pathogenic Neisseria mucosa or Escherichia coli remain in the cytosol. Import of PorB into mitochondria in vivo is independent of a linear signal sequence. Insertion of PorB into the mitochondrial outer membrane in vitro depends on the activity of Tom5, Tom20 and Tom40, but is independent of Tom70. Our data show that human VDAC and bacterial PorB are imported into mitochondria by a similar mechanism. PMID:11953311

  12. Solar hot water system installed at Las Vegas, Nevada

    NASA Technical Reports Server (NTRS)

    1981-01-01

    A solar energy hot water system installed in a motor inn at Las Vegas, Nevada is described. The inn is a three story building with a flat roof for installation of the solar panels. The system consists of 1,200 square feet of liquid flat plate collectors, a 2,500 gallon insulated vertical steel storage tank, two heat exchangers, and pumps and controls. The system was designed to supply approximately 74 percent of the total hot water load.

  13. Language Assessment Scales, LAS I, for Grades K-5, English/Spanish. Second Edition.

    ERIC Educational Resources Information Center

    De Avila, Edward A.; Duncan, Sharon E.

    Language Assessment Scales, LAS I, are designed for children in grades K-5. LAS I accommodates ethnic and linguistic differences and provides direct language activities taken from the popular culture of both English- and Spanish-speaking peoples. LAS I consists of two independent tests, one in English and the other in Spanish, presented largely on…

  14. 40 CFR 81.80 - Las Vegas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Las Vegas Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.80 Las Vegas Intrastate Air Quality Control Region. The Las Vegas...

  15. 40 CFR 81.80 - Las Vegas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Quality Control Regions § 81.80 Las Vegas Intrastate Air Quality Control Region. The Las Vegas Intrastate Air Quality Control Region (Nevada) has been revised to consist of the territorial area encompassed by... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Las Vegas Intrastate Air...

  16. 40 CFR 81.80 - Las Vegas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Quality Control Regions § 81.80 Las Vegas Intrastate Air Quality Control Region. The Las Vegas Intrastate Air Quality Control Region (Nevada) has been revised to consist of the territorial area encompassed by... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Las Vegas Intrastate Air...

  17. GIS methodology for quantifying channel change in Las Vegas, Nevada

    USGS Publications Warehouse

    Buckingham, S.E.; Whitney, J.W.

    2007-01-01

    This study applies spatial analyses to examine the consequences of accelerated urban expansion on a hydrologic system over a period of 24 years. Three sets of historical aerial photos are used in a GIS analysis to document the geomorphic history of Las Vegas Wash, which drains the rapidly growing Las Vegas urban area in southern Nevada. New spatial techniques are introduced to make quantitative measurements of the erosion at three specific time intervals in the hydrologic evolution of the channel and floodplain. Unlike other erosion studies that use two different elevation surfaces to assess erosion, this study used a single elevation surface to remove systematic and nonsystemic elevation errors. The spatial analysis quantifies channel changes for discrete time periods, calculates erosion volumes, and provides a foundation to examine how the specific mechanisms related to urban expansion have affected Las Vegas Wash. The erosion calculated over 24 years is the largest documented sediment loss attributed to the effect of rapid urban growth. ?? 2007 American Water Resources Association.

  18. Geology of Las Vegas, Nevada, United States of America

    SciTech Connect

    Wyman, R.V.; Karakouzian, M. ); Bax-Valentine, V. ); Peterson, L.; Palmer, S. ); Slemmons, D.B.

    1993-03-01

    Las Vegas is one of the fastest growing cities in the US. Its regional geologic setting is in the Basin and Range geomorphic province and in the Sevier orogenic belt. The city itself lies in a broad north-south valley formed by coalescing alluvial fans and lake beds which give rise to several soil and foundation problems. Although destructive earthquakes have not occurred in the Las Vegas area in modern times, the record is very short. Major earthquakes could have taken place in the past when the area was unoccupied except for a few nomadic tribes. Studies are underway to better define the seismicity. Although the climate is hot and dry, flash flooding occurs frequently from late summer thunderstorms and torrential rains. The Regional Flood Control District is actively constructing retention basins and drainage improvements for diversion and protection from such floods. Water supply is a problem for the increasing population. The groundwater supply has long been overdrawn, and the allotment to Nevada under the Colorado River Compact will be completely utilized in the near future. Las Vegas has faced the problems of solid waste disposal, water treatment, rational water use, flooding and earthquakes - all of which are related to the unique geologic and geomorphic setting.

  19. Percepcion de los profesores universitarios acerca del concepto cultura cientifica y de sus implicaciones en el nuevo bachillerato del Recinto de Rio Piedras de la Universidad de Puerto Rico

    NASA Astrophysics Data System (ADS)

    Ramos Pastrana, Nilsa

    El Senado Academico del Recinto de Rio Piedras de la Universidad de Puerto Rico aprobo en el ano academico 2005-2006 la Certificacion 46, que contiene los lineamientos de un nuevo bachillerato. Este nuevo bachillerato introdujo cambios significativos en el curriculo tradicional. Entre ellos se encuentra la reduccion del componente de educacion general y el de Ciencias Biologicas en particular. La reduccion de creditos en el componente de Ciencias Biologicas ha obligado a reevaluar el concepto de cultura cientifica que desarrollan esos cursos. El proposito del estudio consistio en auscultar las percepciones de los profesores de las Facultades de Administracion de Empresas, Humanidades, Ciencias Sociales, Ciencias Naturales, Educacion y Estudios Generales del Recinto de Rio Piedras de la Universidad de Puerto Rico en torno al concepto de cultura cientifica, los contenidos disciplinares del curso de Ciencias Biologicas y la reduccion de creditos en el nuevo bachillerato. Las preguntas que guiaron la investigacion fueron: ¿cuales son las percepciones que tienen los profesores de las Facultades de Administracion de Empresas, Ciencias Sociales, Estudios Generales, Ciencias Naturales, Humanidades y Educacion, en torno al concepto de cultura cientifica y los contenidos disciplinares del curso de Ciencias Biologicas? ¿cuales son las percepciones que tienen los profesores de Ciencias Biologicas en torno al concepto cultura cientifica y los contenidos disciplinares del curso de Ciencias Biologicas? ¿existen diferencias significativas por facultad, genero, experiencia, rango y nombramiento en las percepciones que tienen los profesores del Recinto de Rio Piedras de la Universidad de Puerto Rico sobre los elementos que caracterizan la cultura cientifica y los contenidos biologicos que deben tener los egresados del Recinto? ¿que implicaciones curriculares tienen estos testimonios en el desarrollo del concepto de cultura cientifica en el nuevo bachillerato? Para realizar la

  20. Las1 Is an Essential Nuclear Protein Involved in Cell Morphogenesis and Cell Surface Growth

    PubMed Central

    Doseff, A. I.; Arndt, K. T.

    1995-01-01

    Saccharomyces cerevisiae mutations that cause a requirement for SSD1-v for viability were isolated, yielding one new gene, LAS1, and three previously identified genes, SIT4, BCK1/SLK1, and SMP3. Three of these genes, LAS1, SIT4, and BCK1/SLK1, encode proteins that have roles in bud formation or morphogenesis. LAS1 is essential and loss of LAS1 function causes the cells to arrest as 80% unbudded cells and 20% large budded cells that accumulate many vesicles at the mother-daughter neck. Overexpression of LAS1 results in extra cell surface projections in the mother cell, alterations in actin and SPA2 localization, and the accumulation of electron-dense structures along the periphery of both the mother cell and the bud. The nuclear localization of LAS1 suggests a role of LAS1 for regulating bud formation and morphogenesis via the expression of components that function directly in these processes. PMID:8582632

  1. Geological Mapping Using Legacy Geophysical Data in Las Vegas Valley

    NASA Astrophysics Data System (ADS)

    Donovan, D.; O'Donnell, J.; McLin, K.

    2014-12-01

    In 2008-2011, Clark County, Building Department contracted with Optim to collect 10,700 Reflection Microtremor (ReMi) 600 ft seismic lines that cover most of the metropolitan area of Las Vegas and other outlying communities such as Moapa, Laughlin, Primm, and Coyote Spring. The County completed their goal of characterizing seismic susceptibility of the top 100 ft and the results are posted at http://gisgate.co.clark.nv.us/openweb/. The research question of the authors is: What additional geologic information can be inferred from the data, either through reprocessing, cross correlation of drill hole data or additional data collection? An advantage of geophysical data is that it can be reprocessed to provide additional insight into the local geologic setting. The interpretation is also improved if combined with drill hole data and / or hydrologic information. It should be noted that there is also legacy geophysical data in limited areas collected by the USGS, primarily in conjunction with water well drilling, where some of the ReMi seismic data was collected. An unexpected result of the ReMi survey was a clear delineation of current and paleo channels in Laughlin, Moapa, and Las Vegas. The geometry of the paleochanel, of the Colorado River, is well away from the current position. however the signal is very similar to modern streams such as the Muddy River. Although the surficial geologic mapping in Las Vegas Valley was very detailed, and importantly, was performed prior to development; the new geophysical data provides better details of the lithologic properties of the units. That is it may be an excellent basis for remapping for specific properties related to engineering and hydrologic modeling.

  2. Successful Mnemonics for "por"/"para" and Affirmative Commands with Pronouns.

    ERIC Educational Resources Information Center

    Mason, Keith

    1992-01-01

    Two mnemonic devices, "4A Rule" and "PERFECT," are described to simplify the learning of two grammar points: the placement of object pronouns with respect to commands and the distinction between "por" and "para." (five references) (LB)

  3. Discusión de las aproximaciones utilizadas en el estudio de la recombinación dielectrónica de los metales en envolturas estelares

    NASA Astrophysics Data System (ADS)

    Cruzado, A.; di Rocco, H. O.; Ringuelet, A.

    Se calcularon nuevos parámetros atómicos del MgI reemplazando los niveles de energía teóricos por los observados. Con ellos se calculó nuevamente el flujo originado en la Recombinación Dielectrónica (RD) del MgII y se comparó con resultados anteriores. Se evaluó también la posible influencia de diferentes fuentes de opacidad, en el flujo originado en la RD de los metales en atmósferas extendidas de estrellas tempranas. En particular, se calculó la profundidad óptica de las líneas de MgI para diferentes condiciones físicas del medio.

  4. Genome Sequences of Pseudomonas oryzihabitans Phage POR1 and Pseudomonas aeruginosa Phage PAE1.

    PubMed

    Dyson, Zoe A; Seviour, Robert J; Tucci, Joseph; Petrovski, Steve

    2016-01-01

    We report the genome sequences of two double-stranded DNA siphoviruses, POR1 infective for Pseudomonas oryzihabitans and PAE1 infective for Pseudomonas aeruginosa The phage POR1 genome showed no nucleotide sequence homology to any other DNA phage sequence in the GenBank database, while phage PAE1 displayed synteny to P. aeruginosa phages M6, MP1412, and YuA. PMID:27313312

  5. Genome Sequences of Pseudomonas oryzihabitans Phage POR1 and Pseudomonas aeruginosa Phage PAE1

    PubMed Central

    Dyson, Zoe A.; Seviour, Robert J.; Tucci, Joseph

    2016-01-01

    We report the genome sequences of two double-stranded DNA siphoviruses, POR1 infective for Pseudomonas oryzihabitans and PAE1 infective for Pseudomonas aeruginosa. The phage POR1 genome showed no nucleotide sequence homology to any other DNA phage sequence in the GenBank database, while phage PAE1 displayed synteny to P. aeruginosa phages M6, MP1412, and YuA. PMID:27313312

  6. Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB

    PubMed Central

    Tanabe, Mikio; Nimigean, Crina M.; Iverson, T. M.

    2010-01-01

    PorB is the second most prevalent outer membrane protein in Neisseria meningitidis. PorB is required for neisserial pathogenesis and can elicit a Toll-like receptor mediated host immune response. Here, the x-ray crystal structure of PorB has been determined to 2.3 Å resolution. Structural analysis and cocrystallization studies identify three putative solute translocation pathways through the channel pore: One pathway transports anions nonselectively, one transports cations nonselectively, and one facilitates the specific uptake of sugars. During infection, PorB likely binds host mitochondrial ATP, and cocrystallization with the ATP analog AMP–PNP suggests that binding of nucleotides regulates these translocation pathways both by partial occlusion of the pore and by restricting the motion of a putative voltage gating loop. PorB is located on the surface of N. meningitidis and can be recognized by receptors of the host innate immune system. Features of PorB suggest that Toll-like receptor mediated recognition outer membrane proteins may be initiated with a nonspecific electrostatic attraction. PMID:20351243

  7. An investigation of exploitation versus exploration in GBEA optimization of PORS 15 and 16 Problems

    SciTech Connect

    Koch, Kaelynn

    2012-01-01

    It was hypothesized that the variations in time to solution are driven by the competing mechanisms of exploration and exploitation.This thesis explores this hypothesis by examining two contrasting problems that embody the hypothesized tradeoff between exploration and exploitation. Plus one recall store (PORS) is an optimization problem based on the idea of a simple calculator with four buttons: plus, one, store, and recall. Integer addition and store are classified as operations, and one and memory recall are classified as terminals. The goal is to arrange a fixed number of keystrokes in a way that maximizes the numerical result. PORS 15 (15 keystrokes) represents the subset of difficult PORS problems and PORS 16 (16 keystrokes) represents the subset of PORS problems that are easiest to optimize. The goal of this work is to examine the tradeoff between exploitation and exploration in graph based evolutionary algorithm (GBEA) optimization. To do this, computational experiments are used to examine how solutions evolve in PORS 15 and 16 problems when solved using GBEAs. The experiment is comprised of three components; the graphs and the population, the evolutionary algorithm rule set, and the example problems. The complete, hypercube, and cycle graphs were used for this experiment. A fixed population size was used.

  8. Crystallographic analysis of Neisseria meningitidis PorB extracellular loops potentially implicated in TLR2 recognition.

    PubMed

    Kattner, Christof; Toussi, Deana N; Zaucha, Jan; Wetzler, Lee M; Rüppel, Nadine; Zachariae, Ulrich; Massari, Paola; Tanabe, Mikio

    2014-03-01

    Among all Neisseriae species, Neisseria meningitidis and Neisseria gonorrhoeae are the only human pathogens, causative agents of bacterial meningitis and gonorrhoea, respectively. PorB, a pan-Neisseriae trimeric porin that mediates diffusive transport of essential molecules across the bacterial outer membrane, is also known to activate host innate immunity via Toll-like receptor 2 (TLR2)-mediated signaling. The molecular mechanism of PorB binding to TLR2 is not known, but it has been hypothesized that electrostatic interactions contribute to ligand/receptor binding. Strain-specific sequence variability in the surface-exposed loops of PorB which are potentially implicated in TLR2 binding, may explain the difference in TLR2-mediated cell activation in vitro by PorB homologs from the commensal Neisseriae lactamica and the pathogen N. meningitidis. Here, we report a comparative structural analysis of PorB from N. meningitidis serogroup B strain 8765 (63% sequence homology with PorB from N. meningitidis serogroup W135) and a mutant in which amino acid substitutions in the extracellular loop 7 lead to significantly reduced TLR2-dependent activity in vitro. We observe that this mutation both alters the loop conformation and causes dramatic changes of electrostatic surface charge, both of which may affect TLR2 recognition and signaling. PMID:24361688

  9. Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB

    SciTech Connect

    Tanabe, Mikio; Nimigean, Crina M.; Iverson, T.M.

    2010-06-25

    PorB is the second most prevalent outer membrane protein in Neisseria meningitidis. PorB is required for neisserial pathogenesis and can elicit a Toll-like receptor mediated host immune response. Here, the x-ray crystal structure of PorB has been determined to 2.3 {angstrom} resolution. Structural analysis and cocrystallization studies identify three putative solute translocation pathways through the channel pore: One pathway transports anions nonselectively, one transports cations nonselectively, and one facilitates the specific uptake of sugars. During infection, PorB likely binds host mitochondrial ATP, and cocrystallization with the ATP analog AMP-PNP suggests that binding of nucleotides regulates these translocation pathways both by partial occlusion of the pore and by restricting the motion of a putative voltage gating loop. PorB is located on the surface of N. meningitidis and can be recognized by receptors of the host innate immune system. Features of PorB suggest that Toll-like receptor mediated recognition outer membrane proteins may be initiated with a nonspecific electrostatic attraction.

  10. The Moon Phases in a Paper Box. (Spanish Title: Las Fases de la Luna en Una Caja de Cartón.) As Fases da Lua Numa Caixa de Papelão

    NASA Astrophysics Data System (ADS)

    de Fátima O. Saraiva, Maria; Amador, Cláudio B.; Kemper, Érico; Goulart, Paulo; Muller, Angela

    2007-12-01

    We present a very simple concrete model to demonstrate the concept of phases of an illuminated body. The main objective of our model is to help the understanding of the Moon phases as viewed from the perspective of an observer on Earth. The material allows the visualization of two important effects: (1st) even though all the time half Moon is illuminated by the Sun, we see different fractions of the illuminated Moon surface, depending on our angle of sight; (2nd) the orientation of the convex part of the Moon in the crescent and waning phases on the sky also depends on our perspective from Earth. The use of a closed box allows one to see the contrast among the different phases with no need of a dark room. We also present a text on the Moon phases, emphasizing the dependence of the aspect of the bright part on the angle of sight. En este trabajo proponemos la construcción de material didáctico de bajo costo para demostración del concepto de fases de un cuerpo iluminado. El principal objetivo de nuestro material es facilitar la comprensión de las fases de la Luna desde la perspectiva de un observador en la Tierra. El material ayuda la visualización de dos efectos importantes: (1º) a pesar de tener siempre la mitad de la Luna (representada por una bolita de espuma plástica o de ping-pong), iluminada por el Sol ( representado por una fuente de luz natural o artificial), vemos diferentes fracciones de su superficie iluminada, dependiendo del ángulo por el cual la vemos; (2º) la orientación del borde convexo de la Luna en las fases Creciente y Menguante también depende de la perspectiva por la cual la miramos desde la Tierra. El uso de una caja cerrada permite observar el contraste entre las diferentes fases sin necesidad de estar en un recinto oscuro. Presentamos también un texto explicativo sobre las fases de la Luna, enfatizando la dependencia de la apariencia de la parte iluminada con el ángulo de visión. Neste trabalho propomos a construção de

  11. Fuentes de variabilidad en el diagnóstico de gastritis atrófica multifocal asociada con la infección por Helicobacter pylori1

    PubMed Central

    Bravo, Luis Eduardo; Bravo, Juan Carlos; Realpe, José Luis; Zarama, Guillermo; Piazuelo, MarÍa Blanca; Correa, Pelayo

    2014-01-01

    RESUMEN Introducción El mapeo de las diferentes regiones del estómago y el número de fragmentos de mucosa gástrica disponibles para evaluación histopatológica son fuentes importantes de variación en el momento de clasificar y hacer la gradación de la gastritis crónica. Objetivos Estimar la sensibilidad del número de fragmentos de mucosa gástrica necesarios para establecer los diagnósticos de gastritis atrófica con metaplasia intestinal (MI), displasia y estado de infección por Helicobacter pylori. Además evaluar la variabilidad intra-observador en la clasificación de estas lesiones precursoras del cáncer gástrico. Materiales y métodos En una cohorte de 6 años de seguimiento se evaluaron 1,958 procedimientos de endoscopia realizados por dos gastroenterólogos. En cada procedimiento y de cada participante se obtuvieron 5 biopsias de mucosa gástrica que representaban antro, incisura angularis y cuerpo. Un único patólogo hizo la interpretación histológica de las 5 biopsias y proporcionó un diagnóstico definitivo global que se utilizó como patrón de referencia. Cada fragmento de mucosa gástrica examinado condujo a un diagnóstico individual para cada biopsia que se comparó con el patrón de referencia. La variabilidad intra-observador se evaluó en 127 personas que corresponden a una muestra aleatoria de 20% del total de endoscopias hechas a los 72 meses de seguimiento. Resultados La sensibilidad del diagnóstico de MI y displasia gástrica aumentó de manera significativa con el número de fragmentos de mucosa gástrica evaluados El sitio anatómico de mayor sensibilidad para el diagnóstico de MI y displasia fue la incisura angularis. Para descubrir H. pylori se logró alta sensibilidad con el estudio de un solo fragmento de mucosa gástrica (95.9%) y fue independiente del sitio de obtención de la biopsia. El acuerdo intra-observador para el diagnóstico de gastritis crónica fue 86.1% con valor kappa de 0.79 IC 95% (0.76-0.85). Las

  12. Sexual performance of mass reared and wild Mediterranean fruit flies (Diptera: Tephritidae) from various origins of the Madeira Islands

    SciTech Connect

    Pereira, R.; Silva, N.; Quintal, C.; Abreu, R.; Andrade, J.; Dantas, L.

    2007-03-15

    The success of Mediterranean fruit fly (medfly) Ceratitis capitata (Wiedemann) control programs integrating the sterile insect technique (SIT) is based on the capacity of released the sterile males to compete in the field for mates. The Islands of Madeira are composed of 2 populated islands (Madeira and Porto Santo) where the medfly is present. To evaluate the compatibility and sexual performance of sterile flies we conducted a series of field cage tests. At same time, the process of laboratory domestication was evaluated. 3 wild populations, one semi-wild strain, and 1 mass reared strain were evaluated: the wild populations of (1) Madeira Island (north coast), (2) Madeira Island (south coast), and (3) Porto Santo Island; (4) the semi-wild population after 7 to 10 generations of domestication in the laboratory (respectively, for first and second experiment); and (5) the genetic sexing strain in use at Madeira medfly facility (VIENNA 7mix2000). Field cage experiments showed that populations of all origins are mostly compatible. There were no significant differences among wild populations in sexual competitiveness. Semi-wild and mass-reared males performed significantly poorer in both experiments than wild males in achieving matings with wild females. The study indicates that there is no significant isolation among strains tested, although mating performance is reduced in mass-reared and semi-wild flies after 7 to 10 generations in the laboratory. (author) [Spanish] El exito de los programas de control de la mosca mediterranea de la fruta (Ceratitis capitata (Wiedemann) que integran la tecnica del insecto esteril (TIE) esta basado en la capacidad de machos esteriles para competir en el campo por sus parejas. Las Islas de Madeira consisten de 2 islas pobladas (Madeira y Porto Santo) donde la mosca mediterranea de la fruta esta presente. Para evaluar la compatibilidad y el funcionamiento sexual de moscas esteriles nosotros realizamos una serie de pruebas de jaula en el

  13. Molecular characterisation of Porcine rubulavirus (PorPV) isolates from different outbreaks in Mexico.

    PubMed

    Cuevas-Romero, S; Rivera-Benítez, J F; Blomström, A-L; Ramliden, M; Hernández-Baumgarten, E; Hernández-Jáuregui, P; Ramírez-Mendoza, H; Berg, M

    2016-02-01

    Since the report of the initial outbreak of Porcine rubulavirus (PorPV) infection in pigs, only one full-length genome from 1984 (PorPV-LPMV/1984) has been characterised. To investigate the overall genetic variation, full-length gene nucleotide sequences of current PorPV isolates were obtained from different clinical cases of infected swine. Genome organisation and sequence analysis of the encoded proteins (NP, P, F, M, HN and L) revealed high sequence conservation of the NP protein and the expression of the P and V proteins in all PorPV isolates. The V protein of one isolate displayed a mutation that has been implicated to antagonise the antiviral immune responses of the host. The M protein indicated a variation in a short region that could affect the electrostatic charge and the interaction with the membrane. One PorPV isolate recovered from the lungs showed a mutation at the cleavage site (HRKKR) of the F protein that could represent an important factor to determine the tissue tropism and pathogenicity of this virus. The HN protein showed high sequence identity through the years (up to 2013). Additionally, a number of sequence motifs of very high amino acid conservation among the PorPV isolates important for polymerase activity of the L protein have been identified. In summary, genetic comparisons and phylogenetic analyses indicated that three different genetic variants of PorPV are currently spreading within the swine population, and a new generation of circulating virus with different characteristics has begun to emerge. PMID:26728078

  14. Por Secretion System-Dependent Secretion and Glycosylation of Porphyromonas gingivalis Hemin-Binding Protein 35

    PubMed Central

    Shoji, Mikio; Sato, Keiko; Yukitake, Hideharu; Kondo, Yoshio; Narita, Yuka; Kadowaki, Tomoko; Naito, Mariko; Nakayama, Koji

    2011-01-01

    The anaerobic Gram-negative bacterium Porphyromonas gingivalis is a major pathogen in severe forms of periodontal disease and refractory periapical perodontitis. We have recently found that P. gingivalis has a novel secretion system named the Por secretion system (PorSS), which is responsible for secretion of major extracellular proteinases, Arg-gingipains (Rgps) and Lys-gingipain. These proteinases contain conserved C-terminal domains (CTDs) in their C-termini. Hemin-binding protein 35 (HBP35), which is one of the outer membrane proteins of P. gingivalis and contributes to its haem utilization, also contains a CTD, suggesting that HBP35 is translocated to the cell surface via the PorSS. In this study, immunoblot analysis of P. gingivalis mutants deficient in the PorSS or in the biosynthesis of anionic polysaccharide-lipopolysaccharide (A-LPS) revealed that HBP35 is translocated to the cell surface via the PorSS and is glycosylated with A-LPS. From deletion analysis with a GFP-CTD[HBP35] green fluorescent protein fusion, the C-terminal 22 amino acid residues of CTD[HBP35] were found to be required for cell surface translocation and glycosylation. The GFP-CTD fusion study also revealed that the CTDs of CPG70, peptidylarginine deiminase, P27 and RgpB play roles in PorSS-dependent translocation and glycosylation. However, CTD-region peptides were not found in samples of glycosylated HBP35 protein by peptide map fingerprinting analysis, and antibodies against CTD-regions peptides did not react with glycosylated HBP35 protein. These results suggest both that the CTD region functions as a recognition signal for the PorSS and that glycosylation of CTD proteins occurs after removal of the CTD region. Rabbits were used for making antisera against bacterial proteins in this study. PMID:21731719

  15. Gliding Motility and Por Secretion System Genes Are Widespread among Members of the Phylum Bacteroidetes

    PubMed Central

    Zhu, Yongtao

    2013-01-01

    The phylum Bacteroidetes is large and diverse, with rapid gliding motility and the ability to digest macromolecules associated with many genera and species. Recently, a novel protein secretion system, the Por secretion system (PorSS), was identified in two members of the phylum, the gliding bacterium Flavobacterium johnsoniae and the nonmotile oral pathogen Porphyromonas gingivalis. The components of the PorSS are not similar in sequence to those of other well-studied bacterial secretion systems. The F. johnsoniae PorSS genes are a subset of the gliding motility genes, suggesting a role for the secretion system in motility. The F. johnsoniae PorSS is needed for assembly of the gliding motility apparatus and for secretion of a chitinase, and the P. gingivalis PorSS is involved in secretion of gingipain protease virulence factors. Comparative analysis of 37 genomes of members of the phylum Bacteroidetes revealed the widespread occurrence of gliding motility genes and PorSS genes. Genes associated with other bacterial protein secretion systems were less common. The results suggest that gliding motility is more common than previously reported. Microscopic observations confirmed that organisms previously described as nonmotile, including Croceibacter atlanticus, “Gramella forsetii,” Paludibacter propionicigenes, Riemerella anatipestifer, and Robiginitalea biformata, exhibit gliding motility. Three genes (gldA, gldF, and gldG) that encode an apparent ATP-binding cassette transporter required for F. johnsoniae gliding were absent from two related gliding bacteria, suggesting that the transporter may not be central to gliding motility. PMID:23123910

  16. PREJUICIO Y DISTANCIA SOCIAL HACIA PERSONAS HOMOSEXUALES POR PARTE DE JÓVENES UNIVERSITARIOS

    PubMed Central

    Fernández Rodríguez, María del C.; Squiabro, José Calderón

    2014-01-01

    Se realizó un estudio descriptivo transversal con el propósito de explorar actitudes de rechazo y distancia social hacia las personas gays y lesbianas (GL) en 565 universitarios. Se utilizó una escala para medir Prejuicio y otra escala para medir Distancia Social. Los participantes reflejaron niveles moderados de prejuicio y distancia social (DS) hacia las personas gays y lesbianas. Los varones (M=104.5, DT= 27.47) mostraron significativamente más prejuicio que las mujeres (M=98.8, DT= 23.41). Los hombres (M=22.7, DT= 7.00) mostraron significativamente mayor DS que las mujeres (M=21.1, DT= 5.41). Las personas que asisten con regularidad a la iglesia mostraron más prejuicio y DS que los que no asisten. Se analiza importancia de incluir el tema de la diversidad sexual a través del currículo para desmontar prejuicios hacia la comunidad homosexual. PMID:25606066

  17. City of Las Vegas Plug-in Hybrid Electric Vehicle Demonstration Program

    SciTech Connect

    2013-12-31

    The City of Las Vegas was awarded Department of Energy (DOE) project funding in 2009, for the City of Las Vegas Plug-in Hybrid Electric Vehicle Demonstration Program. This project allowed the City of Las Vegas to purchase electric and plug-in hybrid electric vehicles and associated electric vehicle charging infrastructure. The City anticipated the electric vehicles having lower overall operating costs and emissions similar to traditional and hybrid vehicles.

  18. Fuelwood supply for Managua, Nicaragua sustainable alternatives for the Las Maderas fuelwood supply region

    SciTech Connect

    Park, W.; Newman, L.C.; Ford, K.

    1982-05-01

    This is a preliminary investigation of the fuelwood supply for Managua, Nicaragua, with particular emphasis on the supplies emanating from the area to the Northeast of Managua around the town of Las Maderas. The study assesses the effect of fuelwood harvesting in this area, characterizes the commercial fuelwood industry active between Las Maderas and Managua, and makes a preliminary estimate of the fuelwood supply and demand relationship between the Las Maderas region and Managua.

  19. Environmental levels of Linear alkylbenzene Sulfonates (LAS) in sediments from the Tagus estuary (Portugal): environmental implications.

    PubMed

    Hampel, M; Canário, J; Branco, V; Vale, C; Blasco, J

    2009-02-01

    Sediments from the Tagus estuary (Portugal) were collected at 40 stations in July and December 2004. Total LAS concentrations ranged between 0.03 and 17.76 mg LAS.kg(-1) dry weight in July, and between 0.09 and 9.57 mg LAS.kg(-1) in December. Highest LAS concentrations were found at the upper northern part of the estuary, coincident with the localisation of an important waste water treatment station. According to the Predicted No Effect Concentration (PNEC) of 8.1 mg.kg(-1) derived for this compound, Environmental Risk Assessment (ERA) identified a hazard for the ecosystem at the station with the highest LAS concentration, and similar results are obtained by Equilibrium Partitioning Method (EPM). Nevertheless, LAS concentrations decreased significantly between samplings in the stations with the highest LAS concentrations in July, whereas increased LAS concentrations at adjacent stations were found in December. In the remaining stations, LAS concentrations were up to three orders of magnitude lower, representing no hazard for the sediment community. PMID:18228153

  20. Proteus in flight over mountains near Las Cruces, New Mexico.

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The unique Proteus aircraft served as a test bed for NASA-sponsored flight tests designed to validate collision-avoidance technologies proposed for uninhabited aircraft. The tests, flown over southern New Mexico in March, 2002, used the Proteus as a surrogate uninhabited aerial vehicle (UAV) while three other aircraft flew toward the Proteus from various angles on simulated collision courses. Radio-based 'detect, see and avoid' equipment on the Proteus successfully detected the other aircraft and relayed that information to a remote pilot on the ground at Las Cruces Airport. The pilot then transmitted commands to the Proteus to maneuver it away from the potential collisions. The flight demonstration, sponsored by NASA Dryden Flight Research Center, New Mexico State University, Scaled Composites, the U.S. Navy and Modern Technology Solutions, Inc., were intended to demonstrate that UAVs can be flown safely and compatibly in the same skies as piloted aircraft.

  1. Proteus aircraft over Las Cruces International Airport in New Mexico.

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The unique Proteus aircraft served as a test bed for NASA-sponsored flight tests designed to validate collision-avoidance technologies proposed for uninhabited aircraft. The tests, flown over southern New Mexico in March, 2002, used the Proteus as a surrogate uninhabited aerial vehicle (UAV) while three other aircraft flew toward the Proteus from various angles on simulated collision courses. Radio-based 'detect, see and avoid' equipment on the Proteus successfully detected the other aircraft and relayed that information to a remote pilot on the ground at Las Cruces Airport. The pilot then transmitted commands to the Proteus to maneuver it away from the potential collisions. The flight demonstration, sponsored by NASA Dryden Flight Research Center, New Mexico State University, Scaled Composites, the U.S. Navy and Modern Technology Solutions, Inc., were intended to demonstrate that UAVs can be flown safely and compatibly in the same skies as piloted aircraft.

  2. Proteus aircraft low-level flyby at Las Cruces Airport.

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The unique Proteus aircraft served as a test bed for NASA-sponsored flight tests designed to validate collision-avoidance technologies proposed for uninhabited aircraft. The tests, flown over southern New Mexico in March, 2002, used the Proteus as a surrogate uninhabited aerial vehicle (UAV) while three other aircraft flew toward the Proteus from various angles on simulated collision courses. Radio-based 'detect, see and avoid' equipment on the Proteus successfully detected the other aircraft and relayed that information to a remote pilot on the ground at Las Cruces Airport. The pilot then transmitted commands to the Proteus to maneuver it away from the potential collisions. The flight demonstration, sponsored by NASA Dryden Flight Research Center, New Mexico State University, Scaled Composites, the U.S. Navy and Modern Technology Solutions, Inc., were intended to demonstrate that UAVs can be flown safely and compatibly in the same skies as piloted aircraft.

  3. Dispersion of fruit flies (Diptera: Tephritidae) at high and low densities and consequences of mismatching dispersions of wild and sterile flies

    SciTech Connect

    Meats, A.

    2007-03-15

    dos formas de trampas no fue acompanado por una reduccion en su coeficiente de variacion y cuando las tasas de moscas recapturadas fue alto, el porcentaje de las trampas que capturaron ninguna mosca bajo solo un poco con un aumento en la tasa de las moscas recapturadas, esto indico que no es practicable bajar la heterogenicidad de dispersion de las moscas esteriles por medio de un aumento el numero de moscas liberadas. Muy a menudo se encontro un desajusto entre los patrones de dispersion de las moscas naturales y esteriles, y las implicaciones de esto para la eficiencia de la tecnica del insecto esteril (TIE) fueron investigadas en un estudio de simulacion con los grados de desajustes observados obtenidos de los datos del monitoreo y se considero que la razon general del numero de moscas esteriles a moscas naturales fueron 100:1. La simulacion indico que los desajustes en los patrones de dispersion pueden resultar en una tasa impuesta sobre el aumento de las moscas naturales de hasta 3.5 veces mas alta que la tasa intentada (i.e., 0.35 en vez de 0.1). El efecto de un desajuste siempre reduce la eficiencia de TIS. Se discute la razon para esta asimetria y una comparicion hecha con el sistema de hospedero-parasitoid y otros sistemas. Se sugiere una estrategia de liberacion para contrarrestar este efecto. (author)

  4. Optimization of linear alkylbenzene sulfonate (LAS) degradation in UASB reactors by varying bioavailability of LAS, hydraulic retention time and specific organic load rate.

    PubMed

    Okada, Dagoberto Y; Delforno, Tiago P; Esteves, Andressa S; Sakamoto, Isabel K; Duarte, Iolanda C S; Varesche, Maria B A

    2013-01-01

    Degradation of linear alkylbenzene sulfonate (LAS) in UASB reactors was optimized by varying the bioavailability of LAS based on the concentration of biomass in the system (1.3-16 g TS/L), the hydraulic retention time (HRT), which was operated at 6, 35 or 80 h, and the concentration of co-substrates as specific organic loading rates (SOLR) ranging from 0.03-0.18 g COD/g TVS.d. The highest degradation rate of LAS (76%) was related to the lowest SOLR (0.03 g COD/g TVS.d). Variation of the HRT between 6 and 80 h resulted in degradation rates of LAS ranging from 18% to 55%. Variation in the bioavailability of LAS resulted in discrete changes in the degradation rates (ranging from 37-53%). According to the DGGE profiles, the archaeal communities exhibited greater changes than the bacterial communities, especially in biomass samples that were obtained from the phase separator. The parameters that exhibited more influence on LAS degradation were the SOLR followed by the HRT. PMID:23196232

  5. FLS2 from Solanum tuberosum have interaction with FlaLas from Candidatus Liberibacter asiaticus

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Candidatus Liberibacter asiaticus’ (Las) is a Gram-negative and phloem-limited alphaproteobacterium. Las attacks all citrus species and citrus hybrids in the genus of Citrus and other relatives, and causes a systemic disease. Currently, control of this devastating disease is extremely difficult sinc...

  6. Problem-Solving in Las Vegas: Students Are Building Skills and a Global Network.

    ERIC Educational Resources Information Center

    Budd, Gregory; Curry, Don

    1995-01-01

    Describes a project initiated at Silverado High School in Las Vegas, where students from Las Vegas and schools across the United States monitor the levels of radon in the atmosphere. Enables students to learn first hand about the collection, analysis, and interpretation of scientific data and to network with other students from the United States…

  7. Inhibition of biogas production by alkyl benzene sulfonates (LAS) in a screening test for anaerobic biodegradability.

    PubMed

    Garcia, M Teresa; Campos, Encarna; Dalmau, Manel; Illán, Patricia; Sánchez-Leal, Joaquin

    2006-02-01

    The effect of the inoculum source on the digestion of linear alkylbenzene sulfonates (LAS) under anaerobic conditions has been investigated. The potential for primary and ultimate LAS biodegradation of anaerobic sludge samples obtained from wastewater treatment plants (WWTPs) of different geographical locations was studied applying a batch test system. It was found that only 4-22% of the LAS added to the batch anaerobic digesters was primarily transformed suggesting a poor primary degradation of the LAS molecule in anaerobic discontinuous systems. Regarding ultimate biodegradation, the addition of LAS to the batch anaerobic digesters caused a reduction on the extent of biogas production. Significant differences in the inhibition extent of the biogas production were observed (4-26%) depending on the sludge used as inoculum. Effect of the surfactant on the anaerobic microorganisms was correlated with its concentration in the aqueous phase. Sorption of LAS on anaerobic sludge affects its toxicity by depletion of the available fraction of the surfactant. LAS content on sludge was related to the total amount of calcium and magnesium extractable ions. The presence of divalent cations promote the association of LAS with anaerobic sludge reducing its bioavailability and the extent of its inhibitory effect on the biogas production. PMID:16453170

  8. EFFECT OF SECONDARY EFFLUENTS ON EUTROPHICATION IN LAS VEGAS BAY, LAKE MEAD, NEVADA

    EPA Science Inventory

    The eutrophication potential of Lake Mead, with primary emphasis on Las Vegas Bay, was determined with Selenastrum capricornutum. Nutrient limitation profiles were determined for three sampling stations in Las Vegas Bay and one in Boulder Basin. After heavy metals were chelated w...

  9. REMOTE SENSING OF PERCHLORATE EFFECTS ON SALT CEDAR PRELIMINARY RESULTS FROM THE LAS VEGAS WASH

    EPA Science Inventory



    Sodium Perchlorate and ammonium Perchlorate, major components of solid rocket fuel, have been manufactured in the Las Vegas Valley immediately up gradient from the Las Vegas Wash, since 1945 and 1956, respectively. Measurements of emerging ground water quality in the vici...

  10. A Total Water Management Analysis of the Las Vegas Wash Watershed, Nevada

    EPA Science Inventory

    Climate change, land use change, and population growth are fundamental factors affecting future hydrologic conditions in streams, especially in arid regions with scarce water resources. Located in the arid southwest, Las Vegas Valley located within the Las Vegas Wash watershed is...

  11. 78 FR 65356 - Notice of Public Meeting, Las Cruces District Resource Advisory Council Meeting, New Mexico

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-31

    ... Bureau of Land Management Notice of Public Meeting, Las Cruces District Resource Advisory Council Meeting, New Mexico AGENCY: Bureau of Land Management, Interior. ACTION: Notice of public meeting. SUMMARY: In... of Land Management's (BLM) Las Cruces District Resource Advisory Council (RAC) will meet as...

  12. Oral administration of recombinant Neisseria meningitidis PorA genetically fused to H. pylori HpaA antigen increases antibody levels in mouse serum, suggesting that PorA behaves as a putative adjuvant.

    PubMed

    Vasquez, Abel E; Manzo, Ricardo A; Soto, Daniel A; Barrientos, Magaly J; Maldonado, Aurora E; Mosqueira, Macarena; Avila, Anastasia; Touma, Jorge; Bruce, Elsa; Harris, Paul R; Venegas, Alejandro

    2015-01-01

    The Neisseria meningitidis outer membrane protein PorA from a Chilean strain was purified as a recombinant protein. PorA mixed with AbISCO induced bactericidal antibodies against N. meningitidis in mice. When PorA was fused to the Helicobacter pylori HpaA antigen gene, the specific response against H. pylori protein increased. Splenocytes from PorA-immunized mice were stimulated with PorA, and an increase in the secretion of IL-4 was observed compared with that of IFN-γ. Moreover, in an immunoglobulin sub-typing analysis, a substantially higher IgG1 level was found compared with IgG2a levels, suggesting a Th2-type immune response. This study revealed a peculiar behavior of the purified recombinant PorA protein per se in the absence of AbISCO as an adjuvant. Therefore, the resistance of PorA to proteolytic enzymes, such as those in the gastrointestinal tract, was analyzed, because this is an important feature for an oral protein adjuvant. Finally, we found that PorA fused to the H. pylori HpaA antigen, when expressed in Lactococcus lactis and administered orally, could enhance the antibody response against the HpaA antigen approximately 3 fold. These observations strongly suggest that PorA behaves as an effective oral adjuvant. PMID:25750999

  13. Oral administration of recombinant Neisseria meningitidis PorA genetically fused to H. pylori HpaA antigen increases antibody levels in mouse serum, suggesting that PorA behaves as a putative adjuvant

    PubMed Central

    Vasquez, Abel E; Manzo, Ricardo A; Soto, Daniel A; Barrientos, Magaly J; Maldonado, Aurora E; Mosqueira, Macarena; Avila, Anastasia; Touma, Jorge; Bruce, Elsa; Harris, Paul R; Venegas, Alejandro

    2015-01-01

    The Neisseria meningitidis outer membrane protein PorA from a Chilean strain was purified as a recombinant protein. PorA mixed with AbISCO induced bactericidal antibodies against N. meningitidis in mice. When PorA was fused to the Helicobacter pylori HpaA antigen gene, the specific response against H. pylori protein increased. Splenocytes from PorA-immunized mice were stimulated with PorA, and an increase in the secretion of IL-4 was observed compared with that of IFN-γ. Moreover, in an immunoglobulin sub-typing analysis, a substantially higher IgG1 level was found compared with IgG2a levels, suggesting a Th2-type immune response. This study revealed a peculiar behavior of the purified recombinant PorA protein per se in the absence of AbISCO as an adjuvant. Therefore, the resistance of PorA to proteolytic enzymes, such as those in the gastrointestinal tract, was analyzed, because this is an important feature for an oral protein adjuvant. Finally, we found that PorA fused to the H. pylori HpaA antigen, when expressed in Lactococcus lactis and administered orally, could enhance the antibody response against the HpaA antigen approximately 3 fold. These observations strongly suggest that PorA behaves as an effective oral adjuvant. PMID:25750999

  14. LAS in urban rivers and factors contributing to reduction of their concentrations.

    PubMed

    Kobuke, Y

    2004-01-01

    LC/MS analysis with improved SPE preparation was applied to determine trace amounts of LAS in river waters. By using this procedure, the distribution of LAS was investigated and compared with the previous concentration level measured by HPLC in the Akashi River flowing through urbanized coastal areas in Hyogo Prefecture, western Japan. Detected LAS were in the range of 0.6-11 microg/L and considerably lower than those in 1985. This indicated that LAS concentration levels reduced to 1/10 and below during the past 18 years. From the model analysis, major factors contributing to the reduction of their concentrations were estimated to be the sewerage development and the decrease of consumption of anionic surfactants. Statistical analysis of MBAS monitoring data suggested that over 90% of sewerage diffusion rate was needed in order to reduce LAS to the concentration level of the order of 10 microg/L in river waters. PMID:15497869

  15. Las Vegas Basin Seismic Response Project: Measured Shallow Soil Velocities

    NASA Astrophysics Data System (ADS)

    Luke, B. A.; Louie, J.; Beeston, H. E.; Skidmore, V.; Concha, A.

    2002-12-01

    The Las Vegas valley in Nevada is a deep (up to 5 km) alluvial basin filled with interlayered gravels, sands, and clays. The climate is arid. The water table ranges from a few meters to many tens of meters deep. Laterally extensive thin carbonate-cemented lenses are commonly found across parts of the valley. Lenses range beyond 2 m in thickness, and occur at depths exceeding 200 m. Shallow seismic datasets have been collected at approximately ten sites around the Las Vegas valley, to characterize shear and compression wave velocities in the near surface. Purposes for the surveys include modeling of ground response to dynamic loads, both natural and manmade, quantification of soil stiffness to aid structural foundation design, and non-intrusive materials identification. Borehole-based measurement techniques used include downhole and crosshole, to depths exceeding 100 m. Surface-based techniques used include refraction and three different methods involving inversion of surface-wave dispersion datasets. This latter group includes two active-source techniques, the Spectral Analysis of Surface Waves (SASW) method and the Multi-Channel Analysis of Surface Waves (MASW) method; and a new passive-source technique, the Refraction Mictrotremor (ReMi) method. Depths to halfspace for the active-source measurements ranged beyond 50 m. The passive-source method constrains shear wave velocities to 100 m depths. As expected, the stiff cemented layers profoundly affect local velocity gradients. Scale effects are evident in comparisons of (1) very local measurements typified by borehole methods, to (2) the broader coverage of the SASW and MASW measurements, to (3) the still broader and deeper resolution made possible by the ReMi measurements. The cemented layers appear as sharp spikes in the downhole datasets and are problematic in crosshole measurements due to refraction. The refraction method is useful only to locate the depth to the uppermost cemented layer. The surface

  16. The Understanding of Astronomy Concepts by Students from Basic Education of a Public School. (Spanish Title: El Entendimiento de Conceptos de Aastronmía Por Los Alumnos de Educación Básica en Una Escuela Pública.) O Entendimento de Conceitos de Astronomia Por Alunos da Educação Básica: O Caso de Uma Escola Pública Brasileira

    NASA Astrophysics Data System (ADS)

    Iria Machado, Daniel; dos Santos, Carlos

    2011-07-01

    We present the results obtained in a research on the comprehension of basic astronomical concepts, in which 561 students from fifth grade middle school to third grade high school of a public school of the city of Foz do Iguaçu (Brazil) took part. A test with 20 multiple-choice questions was applied to indentify the most common conceptions expressed by the students. This test was elaborated based on the literature about misconceptions and covered the following topics: the day-night cycle; the time zones; the seasons of the year; the phases of the Moon; the movement of the Moon; the apparent movement of the Sun in the celestial sphere; the eclipses; the dimensions and distances in the Universe; the brightness of the stars and its observation from Earth. Though a small progress was verified in the proportion of scientifically acceptable answers when comparing the eighth grade of middle school to the fifth, and the third grade of high school to the first, there was an overall predominance of alternative conceptions regarding most of the explored subjects, which persisted up to the last year of secondary school. The comparison to data found in this research made in other socio-cultural contexts revealed, in many aspects, similar notions and difficulties revealed by the students. Se presentan los resultados de una investigación sobre la comprensión de conceptos astronómicos básicos, en la cual participaron 561 estudiantes que cursaban entre el quinto grado de la enseñanza primaria y el tercer año de la enseñanza secundaria de una escuela pública de la ciudad de Foz do Iguaçu (Brasil). Se utilizó un test de 20 preguntas de opción múltiple para identificar las concepciones más comunes expresadas por los estudiantes. Este instrumento de recolección de datos se desarrolló en base a la literatura sobre las concepciones alternativas y trató los siguientes temas: el ciclo día-noche, los husos horarios, las estaciones del año, las fases de la Luna, el

  17. The Understanding of Astronomy Concepts by Students from Basic Education of a Public School. (Spanish Title: El Entendimiento de Conceptos de Aastronmía Por Los Alumnos de Educación Básica en Una Escuela Pública.) O Entendimento de Conceitos de Astronomia Por Alunos da Educação Básica: O Caso de Uma Escola Pública Brasileira

    NASA Astrophysics Data System (ADS)

    Iria Machado, Daniel; dos Santos, Carlos

    2011-07-01

    We present the results obtained in a research on the comprehension of basic astronomical concepts, in which 561 students from fifth grade middle school to third grade high school of a public school of the city of Foz do Iguaçu (Brazil) took part. A test with 20 multiple-choice questions was applied to indentify the most common conceptions expressed by the students. This test was elaborated based on the literature about misconceptions and covered the following topics: the day-night cycle; the time zones; the seasons of the year; the phases of the Moon; the movement of the Moon; the apparent movement of the Sun in the celestial sphere; the eclipses; the dimensions and distances in the Universe; the brightness of the stars and its observation from Earth. Though a small progress was verified in the proportion of scientifically acceptable answers when comparing the eighth grade of middle school to the fifth, and the third grade of high school to the first, there was an overall predominance of alternative conceptions regarding most of the explored subjects, which persisted up to the last year of secondary school. The comparison to data found in this research made in other socio-cultural contexts revealed, in many aspects, similar notions and difficulties revealed by the students. Se presentan los resultados de una investigación sobre la comprensión de conceptos astronómicos básicos, en la cual participaron 561 estudiantes que cursaban entre el quinto grado de la enseñanza primaria y el tercer año de la enseñanza secundaria de una escuela pública de la ciudad de Foz do Iguaçu (Brasil). Se utilizó un test de 20 preguntas de opción múltiple para identificar las concepciones más comunes expresadas por los estudiantes. Este instrumento de recolección de datos se desarrolló en base a la literatura sobre las concepciones alternativas y trató los siguientes temas: el ciclo día-noche, los husos horarios, las estaciones del año, las fases de la Luna, el

  18. Enfermedad diarreica aguda por Escherichia coli patógenas en Colombia

    PubMed Central

    Gómez-Duarte, Oscar G.

    2014-01-01

    Resumen Las cepas de E. coli patógenas intestinales son causas importantes de la enfermedad diarreica aguda (EDA) en niños menores de 5 años en América Latina, África y Asia y están asociadas a alta mortalidad en niños en las comunidades más pobres de África y el Sudeste Asiático. Estudios sobre el papel de las E. coli patógenas intestinales en la EDA infantil en Colombia y otros países de América Latina son limitados debido a la carencia de ensayos para detección de estos patógenos en los laboratorios clínicos de centros de salud. Estudios recientes han reportado la detección de E. coli patógenas intestinales en Colombia, siendo la E. coli enterotoxigénica la cepa más frecuentemente asociada a diarrea en niños menores de 5 años. Otros patógenos detectados en estos pacientes incluyen las E. coli enteroagregativa, enteropatógena, productora de toxina Shiga, y de adherencia difusa. Con base en estudios que reportan la presencia de E. coli productora de toxina Shiga y E. coli enteroagregativa en carnes y vegetales en supermercados, se cree que productos alimentarios contaminados contribuyen a la transmisión de estos patógenos y a la infección del huésped susceptible. Más estudios son necesarios para evaluar los mecanismos de transmisión, el impacto en la epidemiologia de la EDA, y las pautas de manejo y prevención de estos patógenos que afectan la población pediátrica en Colombia. PMID:25491457

  19. An Analysis of Interlanguage Development Over Time: Part 1, "por" and "para".

    ERIC Educational Resources Information Center

    Guntermann, Gail

    1992-01-01

    The first part of a larger planned investigation, this study examines the use of "por" and "para" by nine Peace Corps volunteers in oral interviews at the end of training and roughly one year later, to trace their acquisition over time, in two learning contexts. (24 references) (LB)

  20. The Acquisition of Lexical Meaning in a Study Abroad Context: The Spanish Prepositions "por" and "para."

    ERIC Educational Resources Information Center

    Lafford, Barbara A.; Ryan, John M.

    1995-01-01

    Examination of the development of form/function relations of the prepositions "por" and "para" at different levels of proficiency in the interlanguage of study-abroad students in Granada, Spain, revealed "noncanonical" as well as "canonical" uses of these prepositions. The most common noncanonical uses were as substitutions for other prepositions…

  1. The porA gene in serogroup A meningococci: evolutionary stability and mechanism of genetic variation.

    PubMed

    Suker, J; Feavers, I M; Achtman, M; Morelli, G; Wang, J F; Maiden, M C

    1994-04-01

    Molecular analyses were applied to the genes encoding variants of the serosubtyping antigen, the class 1 outer membrane protein (PorA), from 55 serogroup A Neisseria meningitidis strains. These genes were evolutionarily stable and exhibited a limited range of genetic variation, primarily generated by recombination. Translation of the gene sequences revealed a total of 19 distinct amino acid sequences in the variable regions of the protein, 6 of which were not recognized by currently available serosubtyping monoclonal antibodies. Knowledge of these amino acid sequences permitted a rational re-assignment of serosubtype names. Comparison of the complete genes with porA gene sequences from serogroup B and C meningococci showed that serogroup A possessed a limited number of the possible porA genes from a globally distributed gene pool. Each serogroup A subgroup was characterized by one of four porA gene types, probably acquired upon subgroup divergence, which was stable over periods of decades and during epidemiological spread. Comparison with other variable genes (pil and iga) indicated that the three alleles were independently assorted within the subgroup, suggesting that their gene types were older than the subgroups in which they occurred. PMID:8057850

  2. Informe a la Nación de mortalidad por cáncer sigue bajando

    Cancer.gov

    El Informe Anual a la Nación sobre el Estado del Cáncer, de 1975 a 2009, indica que los índices generales de mortalidad por cáncer siguen bajando en los Estados Unidos en hombres y mujeres, entre todos los grupos raciales y étnicos principales y para todo

  3. La problematica de la demarcacion entre ciencia y pseudociencia y sus implicaciones en la educacion cientifica

    NASA Astrophysics Data System (ADS)

    Jimenez Tolentino, Dinorah

    2011-12-01

    En la sociedad prevalece una tendencia generalizada hacia la inclusion de creencias y practicas pseudocientificas. Esta investigacion responde a la necesidad de analizar como la proliferacion de las pseudociencias afecta la vision que tienen los estudiantes universitarios sobre las ciencias naturales. A tales efectos, la investigadora describe las concepciones epistemologicas que tienen los estudiantes sobre las ciencias y las pseudociencias e identifica los criterios de demarcacion, entre un area y otra, que se derivan de estas concepciones. De igual modo, esta identifica las creencias y practicas pseudocientificas de mayor arraigo entre los estudiantes, destacando, a su vez, la razon de ser de las mismas. Por ultimo, la investigadora analiza las implicaciones educativas de la problematica de la demarcacion entre ciencia y pseudociencia. La investigacion es de naturaleza mixta, enmarcada en los paradigmas empirico- analitico y cualitativo. El proceso investigativo se llevo a cabo mediante la administracion del cuestionario Criterios para la demarcacion entre ciencia y pseudociencia. La parte cualitativa estuvo enmarcada en el diseno de estudio de caso, recopilando informacion mediante entrevistas semiestructuradas en dos grupos focales. La poblacion de estudio estuvo constituida por estudiantes universitarios del nivel subgraduado de la Universidad Central de Bayamon. Los resultados del estudio reflejaron las concepciones erroneas de los estudiantes sobre la naturaleza de las ciencias y las pseudociencias. Con respecto a la demarcacion entre ciencia y pseudociencia, el criterio imperante entre los universitarios es el de la verificabilidad, considerando la aplicacion del metodo cientifico como el metodo para demostrar la veracidad de las teorias cientificas. Las creencias y practicas pseudocientificas no son muy frecuentes entre los universitarios. Estos atribuyen las mismas a la prevalencia de elementos supersticiosos y al engano a que es sometida la poblacion

  4. Atmospheric Radioxenon Measurements in North Las Vegas, NV

    SciTech Connect

    Milbrath, Brian D.; Cooper, Matthew W.; Lidey, Lance S.; Bowyer, Ted W.; Hayes, James C.; McIntyre, Justin I.; Karr, L.; Shafer, D.; Tappen, J.

    2006-07-31

    PNNL deployed the ARSA radioxenon measurement system in North Las Vegas for two weeks in February and March 2006 for the purpose of measuring the radioxenon background at a level of sensitivity much higher than previously done in the vicinity of the NTS. The measurements establish what might be expected if future measurements are taken at NTS itself. The measurements are also relevant to test site readiness. A second detector, the PEMS, built and operated by DRI, was deployed in conjunction with the ARSA and contained a PIC, aerosol collection filters, and meteorological sensors. Originally, measurements were also to be performed at Mercury, NV on the NTS, but these were canceled due to initial equipment problems with the ARSA detector. Some of the radioxenon measurements detected 133Xe at levels up to 3 mBq/m3. This concentration of radioxenon is consistent with the observation of low levels of radioxenon emanating from distance nuclear reactors. Previous measurements in areas of high nuclear reactor concentration have shown similar results, but the western US, in general, does not have many nuclear reactors. Measurements of the wind direction indicate that the air carrying the radioxenon came from south of the detector and not from the NTS.

  5. Quorum-sensing-negative (lasR) mutants of Pseudomonas aeruginosa avoid cell lysis and death.

    PubMed

    Heurlier, Karin; Dénervaud, Valérie; Haenni, Marisa; Guy, Lionel; Krishnapillai, Viji; Haas, Dieter

    2005-07-01

    In Pseudomonas aeruginosa, N-acylhomoserine lactone signals regulate the expression of several hundreds of genes, via the transcriptional regulator LasR and, in part, also via the subordinate regulator RhlR. This regulatory network termed quorum sensing contributes to the virulence of P. aeruginosa as a pathogen. The fact that two supposed PAO1 wild-type strains from strain collections were found to be defective for LasR function because of independent point mutations in the lasR gene led to the hypothesis that loss of quorum sensing might confer a selective advantage on P. aeruginosa under certain environmental conditions. A convenient plate assay for LasR function was devised, based on the observation that lasR mutants did not grow on adenosine as the sole carbon source because a key degradative enzyme, nucleoside hydrolase (Nuh), is positively controlled by LasR. The wild-type PAO1 and lasR mutants showed similar growth rates when incubated in nutrient yeast broth at pH 6.8 and 37 degrees C with good aeration. However, after termination of growth during 30 to 54 h of incubation, when the pH rose to > or = 9, the lasR mutants were significantly more resistant to cell lysis and death than was the wild type. As a consequence, the lasR mutant-to-wild-type ratio increased about 10-fold in mixed cultures incubated for 54 h. In a PAO1 culture, five consecutive cycles of 48 h of incubation sufficed to enrich for about 10% of spontaneous mutants with a Nuh(-) phenotype, and five of these mutants, which were functionally complemented by lasR(+), had mutations in lasR. The observation that, in buffered nutrient yeast broth, the wild type and lasR mutants exhibited similar low tendencies to undergo cell lysis and death suggests that alkaline stress may be a critical factor providing a selective survival advantage to lasR mutants. PMID:15995202

  6. Efectos combinados de la ampliación de la atención primaria de salud y de las transferencias condicionadas de dinero en efectivo sobre la mortalidad infantil en Brasil, 1998–2010*

    PubMed Central

    Guanais, Frederico C.

    2015-01-01

    Objetivos. Examiné los efectos combinados del acceso a la atención primaria mediante el Programa de Salud Familiar (PSF) y las transferencias condicionadas de dinero en efectivo del Programa Bolsa Familia (PBF) sobre la mortalidad infantil posneonatal (MIPN) en Brasil. Métodos. Empleé un análisis ecológico longitudinal usando datos en panel de 4 583 municipios brasileños de 1998 al 2010, con 54 253 observaciones en total. Estimé modelos de regresión de efectos fijos por mínimos cuadrados ordinarios, con la tasa de MIPN como la variable dependiente y el PSF, el PBF y sus interacciones como las principales variables independientes de interés. Resultados. La asociación de una mayor cobertura del PSF con una menor tasa de MIPN se volvió más fuerte conforme aumentaba la cobertura del PBF. En los promedios de todas las demás variables, cuando la cobertura de PBF era 25%, la MIPN predicha fue 5,24 (intervalo de confianza [IC] de 95% = 4,95, 5,53) para una cobertura del PSF de 0%, y de 3,54 (IC de 95% = 2,77, 4,31) para una cobertura del PSF de 100%. Cuando la cobertura del PBF era de 60%, la MIPN predicha fue 4,65 (IC de 95% = 4,36, 4,94) para una cobertura del PSF de 0%, y de 1,38 (IC de 95% = 0,88, 1,89) para una cobertura del PSF de 100%. Conclusiones. El efecto del PSF depende de la ampliación del PBF. Para las poblaciones empobrecidas y subatendidas, la combinación de intervenciones tanto del lado de la oferta como del lado de la demanda podría ser necesaria para mejorar los resultados en salud.

  7. Language Assessment Scales, Level 2, LAS II, for Grades 6 and Up, English/Spanish. Examiner's Manual.

    ERIC Educational Resources Information Center

    Duncan, Sharon E.; De Avila, Edward A.

    Language Assessment Scales, Level 2 (LAS II) are used to assess the linguistic proficiency of limited-English-speaking or non-English-speaking adolescents. LAS II, like its predecessor, LAS I, provides a picture of oral linguistic proficiency based on a student's performance across four linguistic subsystems: phonemic, lexical, syntactic and…

  8. 78 FR 32644 - Las Vegas Wash Hydro LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-31

    ... Energy Regulatory Commission Las Vegas Wash Hydro LLC; Notice of Preliminary Permit Application Accepted..., 2012, Las Vegas Wash Hydro LLC, filed an application for a preliminary permit, pursuant to section 4(f) of the Federal Power Act (FPA), proposing to study the feasibility of the Las Vegas...

  9. 40 CFR 81.82 - El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 18 2014-07-01 2014-07-01 false El Paso-Las Cruces-Alamogordo... Designation of Air Quality Control Regions § 81.82 El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region. The El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region (New...

  10. 40 CFR 81.82 - El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 17 2011-07-01 2011-07-01 false El Paso-Las Cruces-Alamogordo... Designation of Air Quality Control Regions § 81.82 El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region. The El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region (New...

  11. 40 CFR 81.82 - El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 18 2013-07-01 2013-07-01 false El Paso-Las Cruces-Alamogordo... Designation of Air Quality Control Regions § 81.82 El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region. The El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region (New...

  12. 40 CFR 81.82 - El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 18 2012-07-01 2012-07-01 false El Paso-Las Cruces-Alamogordo... Designation of Air Quality Control Regions § 81.82 El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region. The El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region (New...

  13. 40 CFR 81.82 - El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false El Paso-Las Cruces-Alamogordo... Designation of Air Quality Control Regions § 81.82 El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region. The El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region (New...

  14. Effects of linear alkylbenzene sulfonate (LAS) on the interspecific competition between Microcystis and Scenedesmus.

    PubMed

    Zhu, Wei; Chen, Huaimin; Guo, Lili; Li, Ming

    2016-08-01

    The widespread use of detergents increases the concentration of surfactant in lakes and reservoirs. High surfactant loads produces toxicity to algae; however, the influence of the increasing surfactant on the competition between algae is not clear. In this paper, different amounts of linear alkylbenzene sulfonate (LAS) were added to test the effects of LAS on the competition between Microcystis aeruginosa and Scenedesmus obliquus under eutrophic condition. In single culture, the growth of S. obliquus was promoted under lower LAS concentrations (1 and 20 mg L(-1)), but cell density of S. obliquus reduced when treated with higher LAS concentration (100 mg L(-1)). The growth of M. aeruginosa was inhibited markedly with 20 and 100 mg L(-1) LAS. Compared with single culture, the result was opposite in co-cultures and the cell density of S. obliquus increased significantly when treated with LAS of 1, 20, and 100 mg L(-1). The specific growth rates of S. obliquus and M. aeruginosa in both cultures were 0.4-0.5 day(-1) and 0.6-0.7 day(-1), respectively, except that the specific growth rate of M. aeruginosa in both cultures treated with 100 mg L(-1) LAS was about 0.2 day(-1). M. aeruginosa dominated over S. obliquus in the co-culture without LAS, while the competition was completely opposite with the addition of 20 mg L(-1) LAS. The growth of S. obliquus treated with 20 mg L(-1) LAS was not affected significantly in single culture but was promoted by 75 % in co-culture. Moreover, the growth of S. obliquus in co-culture treated with 100 mg L(-1) LAS was promoted by more than 97 %. These results suggested that the increasing LAS would overturn the competition of algae in freshwater ecosystems. PMID:27154838

  15. Managing Floods and Resources at the Arroyo Las Positas

    SciTech Connect

    Sanchez, L; Van Hattem, M; Mathews, S

    2002-03-05

    Engineers and water resource professionals are challenged with protecting facilities from flood events within environmental resource protection, regulatory, and economic constraints. One case in point is the Arroyo Las Positas (ALP), an intermittent stream that traverses the Lawrence Livermore National Laboratory (LLNL) in Livermore, California. Increased runoff from post-drought rainfall, upstream development, and new perennial discharges from LLNL activities have resulted in increased dry weather flows and wetland vegetation. These new conditions have recently begun to provide improved habitat for the federally threatened California red-legged frog (Rana aurora draytonii; CRLF), but the additional vegetation diminishes the channel's drainage capacity and increases flood risk. When LLNL proposed to re-grade the channel to reestablish the 100-year flood capacity, traditional dredging practices were no longer being advocated by environmental regulatory agencies. LLNL therefore designed a desilting maintenance plan to protect LLNL facility areas from flooding, while minimizing impacts to wetland resources and habitat. The result was a combination of structural upland improvements and the ALP Five Year Maintenance Plan (Maintenance Plan), which includes phased desilting in segments so that the entire ALP is desilted after five years. A unique feature of the Maintenance Plan is the variable length of the segments designed to minimize LLNL's impact on CRLF movement. State and federal permits also added monitoring requirements and additional constraints on desilting activities. Two years into the Maintenance Plan, LLNL is examining the lessons learned on the cost-effectiveness of these maintenance measures and restrictions and reevaluating the direction of future maintenance activities.

  16. The influence of faults in basin-fill deposits on land subsidence, Las Vegas Valley, Nevada, USA

    NASA Astrophysics Data System (ADS)

    Burbey, Thomas

    2002-07-01

    -dimensional consolidation. Jour. Applied Physics 12:155-164), a été utilisé pour évaluer la nature du déplacement au voisinage de deux failles verticales. La faille a été simulée comme 1) une barrière de faible perméabilité pour l'écoulement horizontal, 2) une rupture structurale dans le milieu, mais sans obstruction de l'écoulement, et 3) une combinaison des deux précédentes conditions. Les résultats indiquent que la barrière de faible perméabilité favorise fortement le déplacement horizontal. Le plan de faille constitue aussi un lieu de subsidence différentielle verticale significative. Les fortes contraintes calculées au voisinage de la faille laissent penser qu'il existe un fort potentiel de rupture et le développement de fissures du sol quand on suppose que la faille possède une faible perméabilité. Les résultats utilisant une combinaison des deux conditions suggèrent que le développement potentiel de fissures peut être grand sur ou à proximité du plan de faille et que la déformation horizontale joue vraisemblablement un rôle clé dans ce développement. Resumen. Se conoce la contribución que la deformación horizontal causada por el bombeo de sistemas acuíferos confinados tienen en el desarrollo de fisuras en regiones semiáridas, como es el caso del Valle de Las Vegas (Nevada, Estados Unidos de América). A pesar de la estabilización de los niveles, se continúa desarrollando nuevas fisuras, mientras las ya existentes se alargan y ensanchan cerca de las fallas de relleno de cuenca. Se ha utilizado un modelo tridimensional de desplazamiento granular basado en la teoría de consolidación de Biot (Biot, M.A., 1941. General theory of three-dimensional consolidation. J. Applied Physics, 12: 155-164) para evaluar la naturaleza del desplazamiento junto a dos fallas verticales. Se ha simulado cada falla como (1) una barrera de baja permeabilidad al flujo horizontal, (2) un hueco o ruptura estructural en el medio pero sin obstrucción al flujo de aguas

  17. The influence of faults in basin-fill deposits on land subsidence, Las Vegas Valley, Nevada, USA

    NASA Astrophysics Data System (ADS)

    Burbey, Thomas

    2002-07-01

    -dimensional consolidation. Jour. Applied Physics 12:155-164), a été utilisé pour évaluer la nature du déplacement au voisinage de deux failles verticales. La faille a été simulée comme 1) une barrière de faible perméabilité pour l'écoulement horizontal, 2) une rupture structurale dans le milieu, mais sans obstruction de l'écoulement, et 3) une combinaison des deux précédentes conditions. Les résultats indiquent que la barrière de faible perméabilité favorise fortement le déplacement horizontal. Le plan de faille constitue aussi un lieu de subsidence différentielle verticale significative. Les fortes contraintes calculées au voisinage de la faille laissent penser qu'il existe un fort potentiel de rupture et le développement de fissures du sol quand on suppose que la faille possède une faible perméabilité. Les résultats utilisant une combinaison des deux conditions suggèrent que le développement potentiel de fissures peut être grand sur ou à proximité du plan de faille et que la déformation horizontale joue vraisemblablement un rôle clé dans ce développement. Resumen. Se conoce la contribución que la deformación horizontal causada por el bombeo de sistemas acuíferos confinados tienen en el desarrollo de fisuras en regiones semiáridas, como es el caso del Valle de Las Vegas (Nevada, Estados Unidos de América). A pesar de la estabilización de los niveles, se continúa desarrollando nuevas fisuras, mientras las ya existentes se alargan y ensanchan cerca de las fallas de relleno de cuenca. Se ha utilizado un modelo tridimensional de desplazamiento granular basado en la teoría de consolidación de Biot (Biot, M.A., 1941. General theory of three-dimensional consolidation. J. Applied Physics, 12: 155-164) para evaluar la naturaleza del desplazamiento junto a dos fallas verticales. Se ha simulado cada falla como (1) una barrera de baja permeabilidad al flujo horizontal, (2) un hueco o ruptura estructural en el medio pero sin obstrucción al flujo de aguas

  18. Double star images taken by HST WFPC and Las Campanas Observatory

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Comparison of the same area of sky (a double star) taken by the Hubble Space Telescope (HST) wide field planetary camera (WFPC) and ground-based image taken from the Las Campanas Observatory, Carnegie Institute of Washington.

  19. 77 FR 77090 - Notice of Public Meeting, Las Cruces District Resource Advisory Council Meeting, New Mexico

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-31

    ...In accordance with the Federal Land Policy and Management Act and the Federal Advisory Committee Act, the Bureau of Land Management's (BLM) Las Cruces District Resource Advisory Council (RAC) will meet as indicated...

  20. ATP for the portable 500 CFM exhauster POR-005 skid C

    SciTech Connect

    Keller, C.M.

    1997-06-27

    This Acceptance Test Plan is for a 500 CFM Portable Exhauster POR-005 to be used for saltwell pumping. The Portable Exhauster System will be utilized to eliminate potential flammable gases that may exist within the dome space of the tank. This Acceptance Plan will test and verify that the exhauster meets the specified design criteria, safety requirements, operations requirements, and will provide a record of the functional test results.

  1. ATP for the portable 500 CFM exhauster POR-006 skid D

    SciTech Connect

    Keller, C.M.

    1997-07-29

    This Acceptance Test Plan is for a 500 CFM Portable Exhauster POR-006 to be used for saltwell pumping. The Portable Exhauster System will be utilized to eliminate potential flammable gases that may exist within the dome space of the tank. This Acceptance Plan will test and verify that the exhauster meets the specified design criteria, safety requirements, operations requirements, and will provide a record of the functional test results.

  2. ATP for the portable 500 CFM exhauster POR-004 skid B

    SciTech Connect

    Keller, C.M.

    1997-05-06

    This Acceptance Test Plan is for a 500 CFM Portable Exhauster POR-004 to be used for saltwell pumping. The Portable Exhauster System will be utilized to eliminate potential flammable gases that may exist within the dome space of the tank. This Acceptance Plan will test and verify that the exhauster meets the specified design criteria, safety requirements, operations requirements, and will provide a record of the functional test results.

  3. Best Practices Case Study: Pulte Homes and Communities of Del Webb, Las Vegas Division

    SciTech Connect

    2009-10-01

    Case study of Pulte Homes Las Vegas Division, who certified nearly 1,200 homes to the DOE Builders Challenge between 2008 and 2012. All of the homes by Las Vegas’ biggest builder achieved HERS scores of lower than 70, and many floor plans got down to the mid 50s, with ducts located in sealed attics insulated along the roof line, advanced framing, and extra attention to air sealing.

  4. LANDSAT-D assessment system library computer compatible tape (LASLIB-CCT/LAS-CCT)

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The format for computer compatible tapes containing thematic mapper archival data and product data generated by the LANDSAT-D Assessment System (LAS). These data tapes are engineering products developed primarily for LAS internal use to assist in the early evaluation of thematic mapper data quality and ground data processing algorithms during the limited period of one year following the launch of LANDSAT-D.

  5. Las características más fascinantes del nuevo Robot

    NASA Video Gallery

    impresionante es la palabra que describe perfectamente al nuevo robot Curiosity por su tamaño, sus instrumentos científicos y la manera en que la NASA planifica hacerlo aterrizar en Marte de forma ...

  6. Correlation between Serological and Sequencing Analyses of the PorB Outer Membrane Protein in the Neisseria meningitidis Serotyping System

    PubMed Central

    Sacchi, Claudio T.; Lemos, Ana P. S.; Whitney, Anne M.; Solari, Claude A.; Brandt, Mary E.; Melles, Carmo E. A.; Frasch, Carl E.; Mayer, Leonard W.

    1998-01-01

    The current serological typing scheme for Neisseria meningitidis is not comprehensive; a proportion of isolates are not serotypeable. DNA sequence analysis and predicted amino acid sequences were used to characterize the structures of variable-region (VR) epitopes on N. meningitidis PorB proteins (PorB VR typing). Twenty-six porB gene sequences were obtained from GenBank and aligned with 41 new sequences. Primary amino acid structures predicted from those genes were grouped into 30 VR families of related variants that displayed at least 60% similarity. We correlated VR families with monoclonal antibody (MAb) reactivities, establishing a relationship between VR families and epitope locations for 15 serotype-defining MAbs. The current panel of serotype-defining MAbs underestimates by at least 50% the PorB VR variability because reagents for several major VR families are lacking or because a number of VR variants within some families are not recognized by serotype-defining MAbs. These difficulties, also reported for serosubtyping based on the PorA protein, are shown as inconsistent results between serological and sequence analyses, leading to inaccurate strain identification and incomplete epidemiological data. The information from this study enabled the expansion of the panel of MAbs currently available for serotyping, by including MAbs of previously undetermined specificities. Use of the expanded serotype panel enabled us to improve the sensitivity of serotyping by resolving a number of formerly nonserotypeable strains. In most cases, this information can be used to predict the VR family placement of unknown PorB proteins without sequencing the entire porB gene. PorB VR typing complements serotyping, and a combination of both techniques may be used for full characterization of meningococcal strains. The present work represents the most complete and integrated data set of PorB VR sequences and MAb reactivities of serogroup B and C meningococci produced to date. PMID

  7. Monitoring Changes in Channel Morphology in Las Vegas Wash with Global Fiducials Program Imagery

    NASA Astrophysics Data System (ADS)

    Wheeler, D. J.

    2012-12-01

    To borrow from a popular adage, "What happens in Las Vegas [Wash], stays in Las Vegas [Wash]"—but only with a lot of help. This past decade has seen a concerted effort to curb erosion and sediment transport along the 12 mile long channel between East Las Vegas and Lake Mead. Las Vegas Wash is prototypical of an urban river in an arid environment that is being impacted by increasing urban development and impervious surface runoff within its drainage area. Rapid urbanization since the 1970s has increased the flow of water into Las Vegas Wash, causing severe channel destabilization. Within two decades millions of cubic yards of rocks and sediment were scoured out of the wash and transported downstream to Lake Mead. The wetlands that once covered over 2,000 acres within Las Vegas Wash dwindled to 200 acres in the 1990s as the channel became as much as 40 feet deeper and 300 feet wider at some points. In 1999 the Las Vegas Wash Coordination Committee (LVWCC) initiated a 20-year plan to construct erosion control structures (weirs) for channel stabilization and rock riprap for stream bank protection. The hope is to design structures that will slow down the water flow, trap sediments, and to eventually restore much of the wetland environment. Using high-resolution satellite imagery from the Global Fiducials Program Library housed at the U. S. Geological Survey, this transition is being tracked from 1999 to the present. From November 1999 to July 2008 new residential and commercial development has claimed an additional 12 square kilometers (3000 acres) of land in Henderson, NV, along the south side of Las Vegas Wash. Even with the increased volume of surface and groundwater runoff entering the wash, current sediment yields are much lower than the 1999 totals. The imagery documents the construction of 14 of the 22 LVWCC planned weirs by the year 2011. It also shows many miles of stream bank stabilization by riprap, planting of riparian vegetation and placing of

  8. Environmentally Endemic Pseudomonas aeruginosa Strains with Mutations in lasR Are Associated with Increased Disease Severity in Corneal Ulcers

    PubMed Central

    Hammond, John H.; Hebert, Wesley P.; Naimie, Amanda; Ray, Kathryn; Van Gelder, Rachel D.; DiGiandomenico, Antonio; Lalitha, Prajna; Srinivasan, Muthiah; Acharya, Nisha R.; Lietman, Thomas; Hogan, Deborah A.

    2016-01-01

    ABSTRACT The Steroids for Corneal Ulcers Trial (SCUT) was a multicenter, international study of bacterial keratitis in which 101 Pseudomonas aeruginosa infections were treated. Twenty-two of 101 P. aeruginosa isolates collected had a colony morphology characteristic of a loss-of-function mutation in lasR, the gene encoding a quorum-sensing master regulator. Ulcers caused by these 22 strains were associated with larger areas of corneal opacification, worse vision, and a lower rate of vision recovery in response to treatment than ulcers caused by the other isolates. The lasR sequences from these isolates each contained one of three nonsynonymous substitutions, and these strains were deficient in production of LasR-regulated protease and rhamnolipids. Replacement of lasR with either of the two most common lasR alleles from the SCUT isolates was sufficient to decrease protease and rhamnolipid production in PA14. Loss of LasR function is associated with increased production of CupA fimbriae, and the LasR-defective isolates exhibited higher production of CupA fimbriae than LasR-intact isolates. Strains with the same lasR mutation were of the same multilocus sequence type, suggesting that LasR-deficient, environmental P. aeruginosa strains were endemic to the area, and infections caused by these strains were associated with worse patient outcomes in the SCUT study. (This study has been registered at ClinicalTrials.gov under registration no. NCT00324168.) IMPORTANCE The LasR transcription factor is an important regulator of quorum sensing in P. aeruginosa and positively controls multiple virulence-associated pathways. The emergence of strains with lasR loss-of-function alleles in chronic disease is well described and is thought to represent a specific adaptation to the host environment. However, the prevalence and virulence of these strains in acute infections remain unclear. This report describes observations revealing that lasR mutants were common among isolates from

  9. Zinc Finger Nuclease Knock-out of NADPH:Cytochrome P450 Oxidoreductase (POR) in Human Tumor Cell Lines Demonstrates That Hypoxia-activated Prodrugs Differ in POR Dependence*

    PubMed Central

    Su, Jiechuang; Gu, Yongchuan; Pruijn, Frederik B.; Smaill, Jeff B.; Patterson, Adam V.; Guise, Christopher P.; Wilson, William R.

    2013-01-01

    Hypoxia, a ubiquitous feature of tumors, can be exploited by hypoxia-activated prodrugs (HAP) that are substrates for one-electron reduction in the absence of oxygen. NADPH:cytochrome P450 oxidoreductase (POR) is considered one of the major enzymes responsible, based on studies using purified enzyme or forced overexpression in cell lines. To examine the role of POR in HAP activation at endogenous levels of expression, POR knock-outs were generated in HCT116 and SiHa cells by targeted mutation of exon 8 using zinc finger nucleases. Absolute quantitation by proteotypic peptide mass spectrometry of DNA sequence-confirmed multiallelic mutants demonstrated expression of proteins with residual one-electron reductase activity in some clones and identified two (Hko2 from HCT116 and S2ko1 from SiHa) that were functionally null by multiple criteria. Sensitivities of the clones to 11 HAP (six nitroaromatics, three benzotriazine N-oxides, and two quinones) were compared with wild-type and POR-overexpressing cells. All except the quinones were potentiated by POR overexpression. Knocking out POR had a marked effect on antiproliferative activity of the 5-nitroquinoline SN24349 in both genetic backgrounds after anoxic exposure but little or no effect on activity of most other HAP, including the clinical stage 2-nitroimidazole mustard TH-302, dinitrobenzamide mustard PR-104A, and benzotriazine N-oxide SN30000. Clonogenic cell killing and reductive metabolism of PR-104A and SN30000 under anoxia also showed little change in the POR knock-outs. Thus, although POR expression is a potential biomarker of sensitivity to some HAP, identification of other one-electron reductases responsible for HAP activation is needed for their rational clinical development. PMID:24196959

  10. University Students' Conceptions about the Moon Phases. (Spanish Title: Concepciones de Estudiantes Universitários sobre Las Fases de la Luna.) Concepções de Estudantes Universitários sobre as Fases da Lua

    NASA Astrophysics Data System (ADS)

    de Fátima Oliveira Saraiva, Maria; da Silveira, Fernando Lang; Steffani, Maria Helena

    2011-07-01

    In this article we describe the development of a multiple choice test about lunar phases and analyze the results of its application to ten groups of Physics students at the UFRGS. During the improvement of the test, we noticed that the percentage of right answers about some concepts increased significantly when associated with the reformulation of the question, emphasizing the importance of being careful to avoid incorrect answers generated by unclear questions, and not by ignorance on the matter. We confirm the results of other studies that show that students have great difficulty to relate the Moon's phase with its position in the sky at given time. On the other hand, our results suggest that, in general, students of Physics understand the phenomenon of lunar phases better than the average of university students. En estese artículo se describe la elaboración de una prueba de opción múltiple sobre las fases de la Luna y se analizan los resultados de su aplicación en diez grupos de estudiantes de Física de UFRGS. Durante el mejoramiento de la prueba observamos que el porcentaje de aciertos creció considerablemente cuando considerada una nueva redacción de la pregunta, destacando el cuidado que se debe tomar a fin de evitar respuestas incorrectas generadas por preguntas poco claras y no a causa de la ignorancia de los estudiantes sobre el tema. Confirmamos los resultados de otros estudios que las mayores dificultades de los alumnos sobre el tema fases de la Luna están en relacionar la fase de la Luna con su posición en el cielo en determinado momento. Por otra parte, nuestros resultados sugieren que, en general, los estudiantes de la Física comprenden mejor el fenómeno de las fases lunares que el promedio de los estudiantes universitarios. Neste artigo descrevemos a elaboração de um teste de múltipla escolha sobre as fases da Lua e analisamos os resultados de sua aplicação em dez grupos de estudantes de Física da UFRGS. Durante o aprimoramento do

  11. Molecular Insights into the Impact of Oxidative Stress on the Quorum-Sensing Regulator Protein LasR.

    PubMed

    Kafle, Prapti; Amoh, Amanda N; Reaves, Jocelyn M; Suneby, Emma G; Tutunjian, Kathryn A; Tyson, Reed L; Schneider, Tanya L

    2016-05-27

    The LasR regulator protein functions at the top of the Pseudomonas aeruginosa quorum-sensing hierarchy and is implicated in promoting bacterial virulence. Of note is recent evidence that this transcription factor may also respond to oxidative stress. Here, all cysteines in LasR were inspected to deduce their redox sensitivity and to probe the connection between stress response and LasR activity using purified LasR and individual LasR domains. Cys(79) in the ligand binding domain of LasR appears to be important for ligand recognition and folding of this domain to potentiate DNA binding but does not seem to be sensitive to oxidative stress when bound to its native ligand. Two cysteines in the DNA binding domain of LasR do form a disulfide bond when treated with hydrogen peroxide, and formation of this Cys(201)-Cys(203) disulfide bond appears to disrupt the DNA binding activity of the transcription factor. Mutagenesis of either of these cysteines leads to expression of a protein that no longer binds DNA. A cell-based reporter assay linking LasR function with β-galactosidase activity gave results consistent with those obtained with purified LasR. This work provides a possible mechanism for oxidative stress response by LasR and indicates that multiple cysteines within the protein may prove to be useful targets for disabling its activity. PMID:27053110

  12. Characterization of Plasmid pOR1 from Ornithobacterium rhinotracheale and Construction of a Shuttle Plasmid

    PubMed Central

    Jansen, Ruud; Chansiripornchai, Niwat; Gaastra, Wim; van Putten, Jos P. M.

    2004-01-01

    The bacterium Ornithobacterium rhinotracheale has been recognized as an emerging pathogen in poultry since about 10 years ago. Knowledge of this bacterium and its mechanisms of virulence is still very limited. Here we report the development of a transformation system that enables genetic modification of O. rhinotracheale. The system is based on a cryptic plasmid, pOR1, that was derived from an O. rhinotracheale strain of serotype K. Sequencing indicated that the plasmid consisted of 14,787 nucleotides. Sequence analysis revealed one replication origin and several rep genes that control plasmid replication and copy number, respectively. In addition, pOR1 contains genes with similarity to a heavy-metal-transporting ATPase, a TonB-linked siderophore receptor, and a laccase. Reverse transcription-PCR demonstrated that these genes were transcribed. Other putative open reading frames exhibited similarities with a virulence-associated protein in Actinobacillus actinomycetemcomitans and a number of genes coding for proteins with unknown function. An Escherichia coli-O. rhinotracheale shuttle plasmid (pOREC1) was constructed by cloning the replication origin and rep genes from pOR1 and the cfxA gene from Bacteroides vulgatus, which codes for resistance to the antibiotic cefoxitin, into plasmid pGEM7 by using E. coli as a host. pOREC1 was electroporated into O. rhinotracheale and yielded cefoxitin-resistant transformants. The pOREC1 isolated from these transformants was reintroduced into E. coli, demonstrating that pOREC1 acts as an independent replicon in both E. coli and O. rhinotracheale, fulfilling the criteria for a shuttle plasmid that can be used for transformation, targeted mutagenesis, and the construction of defined attenuated vaccine strains. PMID:15466524

  13. Expression, purification and preliminary X-ray analysis of the Neisseria meningitidis outer membrane protein PorB

    SciTech Connect

    Tanabe, Mikio; Iverson, Tina M.

    2010-01-28

    The Neisseria meningitidis outer membrane protein PorB was expressed in Escherichia coli and purified from inclusion bodies by denaturation in urea followed by refolding in buffered LDAO on a size-exclusion column. PorB has been crystallized in three different crystal forms: C222, R32 and P6{sub 3}. The C222 crystal form may contain either one or two PorB monomers in the asymmetric unit, while both the R32 and P6{sub 3} crystal forms contained one PorB monomer in the asymmetric unit. Of the three, the P6{sub 3} crystal form had the best diffraction quality, yielding data extending to 2.3 {angstrom} resolution.

  14. Application of POR-Tveks to the radiochemical recovery of yttrium-90

    SciTech Connect

    Maksimova, A.M.; Kvasnitskii, I.B.

    1988-01-01

    The authors describe a method for the radiochemical analysis of fish bones for the accumulation of strontium 90 and yttrium 90 from power plant contamination of surface waters which involves labelling the sample with isotopes and subsequent adsorption of the yttrium component with the use of POR-Tveks, an adsorbent based on a copolymer of styrene and divinylbenzene with heteroradical phosphine oxide. The yield of yttrium is determined from the mass of the oxide and from the half-life of the yttrium isotope.

  15. El fenotipo de las mucinas en el esófago de Barrett

    PubMed Central

    Torrado, Julio; Piazuelo, María Blanca; Ruiz, Irune; Izarzugaza, María Isabel; Camargo, María Constanza; Delgado, Alberto; Abdirad, Afshin; Correa, Pelayo

    2011-01-01

    Antecedentes El esófago de Barrett es una reconocida lesión precursora de adenocarcinoma esofágico. Aunque generalmente asociada al reflujo gastroesofágico, los mecanismos patogénicos de la enfermedad no son bien conocidos. El objetivo del presente estudio es explorar la historia natural e identificar marcadores de progreso del proceso precanceroso. Material y métodos Se utilizaron cortes histológicos de 67 especímenes de esófago correspondientes a 14 pacientes con esófago de Barrett, a los que se siguió entre 1 – 9 años. Se clasificaron las lesiones en: esófago de Barrett sin displasia, indefinido para displasia o con displasia. Se evaluó la expresión de diferentes mucinas en las células caliciformes y en las columnares usando técnicas de histoquímica e inmunohistoquímica. Resultados En todos los casos se comprobó la presencia de metaplasia intestinal incompleta. Las células columnares dentro del epitelio metaplásico contenían mucinas neutras. A mayor severidad de la lesión se encontró significativamente menor expresión de sialomucinas en las células columnares (p de tendencia igual a 0,03). En sujetos con lesiones indefinidas para displasia se observó un mayor contenido de sulfomucinas en las células caliciformes (p=0,034) y de MUC2 en las células columnares (p=0,029) que en sujetos con esófago de Barrett sin displasia. Se observó expresión de la mucina intestinal MUC2 y de la mucina gástrica MUC5AC en todas las muestras. MUC6, una mucina de las glándulas profundas gástricas, se presentó ocasionalmente. Conclusión La evaluación de los perfiles de mucinas en el esófago de Barrett sugiere una transición gradual del fenotipo del epitelio metaplásico a medida que la lesión avanza en el tiempo. PMID:21804831

  16. Antigenic topology of chlamydial PorB protein and identification of targets for immune neutralization of infectivity.

    PubMed

    Kawa, Diane E; Stephens, Richard S

    2002-05-15

    The outer membrane protein PorB is a conserved chlamydial protein that functions as a porin and is capable of eliciting neutralizing Abs. A topological antigenic map was developed using overlapping synthetic peptides representing the Chlamydia trachomatis PorB sequence and polyclonal immune sera. To identify which antigenic determinants were surface accessible, monospecific antisera were raised to the PorB peptides and were used in dot-blot and ELISA-based absorption studies with viable chlamydial elementary bodies (EBs). The ability of the surface-accessible antigenic determinants to direct neutralizing Ab responses was investigated using standardized in vitro neutralization assays. Four major antigenic clusters corresponding to Phe(34)-Leu(59) (B1-2 and B1-3), Asp(112) -Glu(145) (B2-3 and B2-4), Gly(179)-Ala(225) (B3-2 to B3-4), and Val(261)-Asn(305) (B4-4 to B5-2) were identified. Collectively, the EB absorption and dot-blot assays established that the immunoreactive PorB Ags were exposed on the surface of chlamydial EBs. Peptide-specific antisera raised to the surface-accessible Ags neutralized chlamydial infectivity and demonstrated cross-reactivity to synthetic peptides representing analogous C. pneumoniae PorB sequences. Furthermore, neutralization of chlamydial infectivity by C. trachomatis PorB antisera was inhibited by synthetic peptides representing the surface-exposed PorB antigenic determinants. These findings demonstrate that PorB Ags may be useful for development of chlamydial vaccines. PMID:11994474

  17. Cystic fibrosis–adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses

    PubMed Central

    LaFayette, Shantelle L.; Houle, Daniel; Beaudoin, Trevor; Wojewodka, Gabriella; Radzioch, Danuta; Hoffman, Lucas R.; Burns, Jane L.; Dandekar, Ajai A.; Smalley, Nicole E.; Chandler, Josephine R.; Zlosnik, James E.; Speert, David P.; Bernier, Joanie; Matouk, Elias; Brochiero, Emmanuelle; Rousseau, Simon; Nguyen, Dao

    2015-01-01

    Cystic fibrosis lung disease is characterized by chronic airway infections with the opportunistic pathogen Pseudomonas aeruginosa and severe neutrophilic pulmonary inflammation. P. aeruginosa undergoes extensive genetic adaptation to the cystic fibrosis (CF) lung environment, and adaptive mutations in the quorum sensing regulator gene lasR commonly arise. We sought to define how mutations in lasR alter host-pathogen relationships. We demonstrate that lasR mutants induce exaggerated host inflammatory responses in respiratory epithelial cells, with increased accumulation of proinflammatory cytokines and neutrophil recruitment due to the loss of bacterial protease–dependent cytokine degradation. In subacute pulmonary infections, lasR mutant–infected mice show greater neutrophilic inflammation and immunopathology compared with wild-type infections. Finally, we observed that CF patients infected with lasR mutants have increased plasma interleukin-8 (IL-8), a marker of inflammation. These findings suggest that bacterial adaptive changes may worsen pulmonary inflammation and directly contribute to the pathogenesis and progression of chronic lung disease in CF patients. PMID:26457326

  18. Evaluation of Linear Alkylbenzene Sulfonate (LAS) behaviour in agricultural soil through laboratory continuous studies.

    PubMed

    Oliver-Rodríguez, B; Zafra-Gómez, A; Reis, M S; Duarte, B P M; Verge, C; de Ferrer, J A; Pérez-Pascual, M; Vílchez, J L

    2015-07-01

    The behaviour of Linear Alkylbenzene Sulfonate (LAS) in agricultural soil is investigated in the laboratory using continuous-flow soil column studies in order to simultaneously analyze the three main underlying phenomena (adsorption/desorption, degradation and transport). The continuous-flow soil column experiments generated the breakthrough curves for each LAS homologue, C10, C11, C12 and C13, and by adding them up, for total LAS, from which the relevant retention, degradation and transport parameters could be estimated, after proposing adequate models. Several transport equations were considered, including the degradation of the sorbate in solution and its retention by soil, under equilibrium and non-equilibrium conditions between the sorbent and the sorbate. In general, the results obtained for the estimates of those parameters that were common to the various models studied (such as the isotherm slope, first order degradation rate coefficient and the hydrodynamic dispersion coefficient) were rather consistent, meaning that mass transfer limitations are not playing a major role in the experiments. These three parameters increase with the length of the LAS homologue chain. The study will provide the underlying conceptual framework and fundamental parameters to understand, simulate and predict the environmental behaviour of LAS compounds in agricultural soils. PMID:25765258

  19. Multiple active site residues are important for photochemical efficiency in the light-activated enzyme protochlorophyllide oxidoreductase (POR).

    PubMed

    Menon, Binuraj R K; Hardman, Samantha J O; Scrutton, Nigel S; Heyes, Derren J

    2016-08-01

    Protochlorophyllide oxidoreductase (POR) catalyzes the light-driven reduction of protochlorophyllide (Pchlide), an essential, regulatory step in chlorophyll biosynthesis. The unique requirement of the enzyme for light has provided the opportunity to investigate how light energy can be harnessed to power biological catalysis and enzyme dynamics. Excited state interactions between the Pchlide molecule and the protein are known to drive the subsequent reaction chemistry. However, the structural features of POR and active site residues that are important for photochemistry and catalysis are currently unknown, because there is no crystal structure for POR. Here, we have used static and time-resolved spectroscopic measurements of a number of active site variants to study the role of a number of residues, which are located in the proposed NADPH/Pchlide binding site based on previous homology models, in the reaction mechanism of POR. Our findings, which are interpreted in the context of a new improved structural model, have identified several residues that are predicted to interact with the coenzyme or substrate. Several of the POR variants have a profound effect on the photochemistry, suggesting that multiple residues are important in stabilizing the excited state required for catalysis. Our work offers insight into how the POR active site geometry is finely tuned by multiple active site residues to support enzyme-mediated photochemistry and reduction of Pchlide, both of which are crucial to the existence of life on Earth. PMID:27285815

  20. Effect of SPM-based cleaning POR on EUV mask performance

    NASA Astrophysics Data System (ADS)

    Choi, Jaehyuck; Lee, Han-shin; Yoon, Jinsang; Shimomura, Takeya; Friz, Alex; Montgomery, Cecilia; Ma, Andy; Goodwin, Frank; Kang, Daehyuk; Chung, Paul; Shin, Inkyun; Cho, H.

    2011-11-01

    EUV masks include many different layers of various materials rarely used in optical masks, and each layer of material has a particular role in enhancing the performance of EUV lithography. Therefore, it is crucial to understand how the mask quality and patterning performance can change during mask fabrication, EUV exposure, maintenance cleaning, shipping, or storage. The fact that a pellicle is not used to protect the mask surface in EUV lithography suggests that EUV masks may have to undergo more cleaning cycles during their lifetime. More frequent cleaning, combined with the adoption of new materials for EUV masks, necessitates that mask manufacturers closely examine the performance change of EUV masks during cleaning process. We have investigated EUV mask quality and patterning performance during 30 cycles of Samsung's EUV mask SPM-based cleaning and 20 cycles of SEMATECH ADT exposure. We have observed that the quality and patterning performance of EUV masks does not significantly change during these processes except mask pattern CD change. To resolve this issue, we have developed an acid-free cleaning POR and substantially improved EUV mask film loss compared to the SPM-based cleaning POR.

  1. Methodology for obtaining stakeholder assessments of obesity policy options in the PorGrow project.

    PubMed

    Stirling, A; Lobstein, T; Millstone, E

    2007-05-01

    The Policy Options for Responding to the Growing Challenge of Obesity Research Project (PorGrow) study provided a unique opportunity to develop a large-scale application of a semi-quantitative technique for exploring interviewees' views on options to tackle obesity, using multi-criteria mapping. This 'heuristic' approach utilizes the advantages of a structured interviews framework by predefining a set of options for appraisal, while leaving interviewees free to select their own criteria for making their judgements. Additional information can be gleaned from the interview transcripts and related materials to set the appraisals in their policy context, and allowing interviewees to express their views on the options presented and their own appraisals. The PorGrow study team agreed a predefined set of 20 options for appraisal, and interviewed sets of stakeholders representing more than 20 aspects of policy development in each of the nine participating countries. The details of the methodology adopted are set out in this paper. PMID:17371304

  2. Carbon Dioxide Laser Absorption Spectrometer (CO2LAS) Aircraft Measurements of CO2

    NASA Technical Reports Server (NTRS)

    Christensen, Lance E.; Spiers, Gary D.; Menzies, Robert T.; Jacob, Joseph C.; Hyon, Jason

    2011-01-01

    The Jet Propulsion Laboratory Carbon Dioxide Laser Absorption Spectrometer (CO2LAS) utilizes Integrated Path Differential Absorption (IPDA) at 2.05 microns to obtain CO2 column mixing ratios weighted heavily in the boundary layer. CO2LAS employs a coherent detection receiver and continuous-wave Th:Ho:YLF laser transmitters with output powers around 100 milliwatts. An offset frequency-locking scheme coupled to an absolute frequency reference enables the frequencies of the online and offline lasers to be held to within 200 kHz of desired values. We describe results from 2009 field campaigns when CO2LAS flew on the Twin Otter. We also describe spectroscopic studies aimed at uncovering potential biases in lidar CO2 retrievals at 2.05 microns.

  3. Identification of methyl triclosan and halogenated analogues in male common carp (Cyprinus carpio) from Las Vegas Bay and semipermeable membrane devices from Las Vegas Wash, Nevada

    USGS Publications Warehouse

    Leiker, T.J.; Abney, S.R.; Goodbred, S.L.; Rosen, Michael R.

    2009-01-01

    Methyl triclosan and four halogenated analogues have been identified in extracts of individual whole-body male carp (Cyprinus carpio) tissue that were collected from Las Vegas Bay, Nevada, and Semipermeable Membrane Devices (SPMD) that were deployed in Las Vegas Wash, Nevada. Methyl triclosan is believed to be the microbially methylated product of the antibacterial agent triclosan (2, 4, 4'-trichloro-4-hydroxydiphenyl ether, Chemical Abstract Service Registry Number 3380-34-5, Irgasan DP300). The presence of methyl triclosan and four halogenated analogues was confirmed in SPMD extracts by comparing low- and high-resolution mass spectral data and Kovats retention indices of methyl triclosan with commercially obtained triclosan that was derivatized to the methyl ether with ethereal diazomethane. The four halogenated analogues of methyl triclosan detected in both whole-body tissue and SPMD extracts were tentatively identified by high resolution mass spectrometry. Methyl triclosan was detected in all 29 male common carp from Las Vegas Bay with a mean concentration of 596????g kg- 1 wet weight (ww) which is more than an order of magnitude higher than previously reported concentrations in the literature. The halogenated analogs were detected less frequently (21%-76%) and at much lower concentrations (< 51????g kg- 1 ww). None of these compounds were detected in common carp from a Lake Mead reference site in Overton Arm, Nevada.

  4. Las17p-Vrp1p but not Las17p-Arp2/3 interaction is important for actin patch polarization in yeast.

    PubMed

    Rajmohan, Rajamuthiah; Wong, Ming Hwa; Meng, Lei; Munn, Alan L; Thanabalu, Thirumaran

    2009-05-01

    The actin cytoskeleton plays a central role in many important cellular processes such as cell polarization, cell division and endocytosis. The dynamic changes to the actin cytoskeleton that accompany these processes are regulated by actin-associated proteins Wiskott-Aldrich Syndrome Protein (WASP) (known as Las17p in yeast) and WASP-Interacting Protein (WIP) (known as Vrp1p in yeast). Both yeast and human WASP bind to and stimulate the Arp2/3 complex which in turn nucleates assembly of actin monomers into filaments at polarized sites at the cortex. WASP-WIP interaction in yeast and humans are important for Arp2/3 complex stimulation in vitro. It has been proposed that these interactions are also important for polarized actin assembly in vivo. However, the redundancy of actin-associated proteins has made it difficult to test this hypothesis. We have identified two point mutations (L80T and H94L) in yeast WASP that in combination abolish WASP-WIP interaction in yeast. We also identify an N-terminal fragment of Las17p (N-Las17p1-368) able to interact with Vrp1p but not Arp2/3. Using these mutant and truncated forms of yeast WASP we provide novel evidence that WASP interaction with WIP is more important than interaction with Arp2/3 for polarized actin assembly and endocytosis in yeast. PMID:19272406

  5. Effects of heme precursors on CYP1A2 and POR expression in the baculovirus/Spodoptera frugiperda system☆

    PubMed Central

    Lu, Huiyuan; Ma, Jun; Liu, Nian; Wang, Shoulin

    2010-01-01

    Objective CYP1A2 and NADPH-CYP450 oxidoreductase (POR) were expressed in the baculovirus/Spodoptera frugiperda (sf9) system. The aim of this study was to investigate the effects of heme precursors on the expression of CYP1A2 and POR. Methods The heme precursors [δ-Aminolaevulinic Acid (5-ALA), Fe3+ and hemin] were introduced into the system to evaluate their effects on the expression of CYP1A2, POR and their co-expression. All the proteins were identified using immunoblotting, CO-difference spectroscopy, or cytochrome c assay. Results In the present study, functional CYP1A2 and POR were successfully expressed in the baculovirus/sf9 system, and both of them showed high activities. Co-addition of 5-ALA and Fe3+ significantly improved expression of CYP1A2 by about 50% compared with the addition of 5-ALA, Fe3+ or hemin alone. Either co-addition of 5-ALA and Fe3+ or addition of 5-ALA or Fe3+ alone improved the POR expression level 2 fold and its activity 7-10 fold compared with control (no addition). However, unlike CYP1A2, there was no difference between the co-addition and addition of these heme precursors alone. Different ratios of BvCYP1A2 to BvPOR also affected the co-expression of CYP1A2 and POR, with a 3:1 ratio of BvCYP1A2 / BvPOR significantly increasing their co-expression. Surprisingly, the addition of 0.1 mM 5-ALA or Fe3+ alone, but not their co-addition, could significantly improve the CYP1A2 and POR co-expression (P < 0.05). Conclusion 5-ALA and Fe3+ increased the expression of CYP1A2 and POR in a baculovirus/sf9 system, but the pattern of their expression was different between their expression alone and co-expression. PMID:23554636

  6. Methanogenic activity inhibition by increasing the linear alkylbenzene sulfonate (LAS) concentration.

    PubMed

    Souza, Luiza F C; Florencio, Lourdinha; Gavazza, Savia; Kato, Mario T

    2016-07-01

    The effect of the initial concentration of linear alkylbenzene sulfonate (LAS) on specific methanogenic activity (SMA) was investigated in this work. Six anaerobic flasks reactors with 1 L of total volume were inoculated with anaerobic sludge (2 g VSS L(-1)). The reactors were assayed for 42 days, and fed with volatile fatty acids, nutrients, and LAS. The initial LAS concentrations were 0, 10, 30, 50, 75, and 100 mg L(-1) for the treatment flasks T1 (control), T2, T3, T4, T5, and T6, respectively. When compared with T1, T2 exhibited a 30% reduction in maximum SMA and total methane production (TMP). In treatment T3 through T6, the reductions were 44-97% (T3-T6) for SMA, and 30-90% (T3-T6) for TMP. Total LAS removal increased following the increase in the initial LAS concentration (from 36% at T1 to 76% at T6), primarily due to the high degree of sludge adsorption. LAS biodegradation also occurred (32% in all treatments), although this was most likely associated with the formation of non-methane intermediates. Greater removal by adsorption was observed in long-chain homologues, when compared to short-chain homologues (C13 > C10), whereas the opposite occurred for biodegradation (C10 > C13). The C13 homologue was adsorbed to a great extent (in mass) in T4, T5 and T6, and may also have inhibited methane formation in these treatments. PMID:27088975

  7. A reinterpretation of the Pleistocene human and faunal association at Las Buitreras Cave, Santa Cruz, Argentina

    NASA Astrophysics Data System (ADS)

    Borrero, Luis A.; Martin, Fabiana M.

    2008-12-01

    The faunal assemblage recovered from Layers VIII-VII at Las Buitreras Cave has been considered as associated with human artifacts. On that basis, the previous analysis had concluded that human hunters had exploited ground sloths at the end of the Pleistocene. A reanalysis of the bones as well as the rest of the evidence suggests that there is no basis for that conclusion. On the contrary, it is suggested here that the lower layers at Las Buitreras are the result of the use of the cave as a den by ground sloths.

  8. Geometry sensing through POR1 regulates Rac1 activity controlling early osteoblast differentiation in response to nanofiber diameter.

    PubMed

    Higgins, A M; Banik, B L; Brown, J L

    2015-02-01

    Bone grafting procedures in the United States rely heavily upon autografts and allografts, which are donor-dependent, cause donor site pain, and can transmit disease. Synthetic bone grafts can reduce these risks; however, synthetics lack the bone differentiating (osteoinductive) abilities of auto- and allografts. Achieving innate osteoinductive properties of synthetics through surface modifications is currently under investigation. This study focuses on nanofibers, with emphasis on how fiber diameter and the potential curvature sensor POR1 affect the activation of the signaling molecules Rac1 and Arf1, and leading to expression of alkaline phosphatase (ALP), an osteoinductive marker. Diameters of 0.1, 0.3, and 1.0 μm were compared against a flat control. The highest level of Rac1 activation was achieved on the smallest fibers (0.1 μm), a trend that was lost in POR1 knockdowns. This supports the hypothesis that on small nanofibers, POR1 favorably binds to highly curved cell membranes, which allows Rac1 to subsequently dissociate and activate. When the curvature is insufficient to bind POR1, POR1 binds to inactive Rac1 and competitively inhibits its activation. Arf1 activation followed an opposite trend, with the largest nanofibers exhibiting the highest activity. This trend reinforces the known interaction between Rac1 and Arf1 through the GIT-PIX complex, an Arf1 GAP and Rac1 GEF, respectively. Large, (1.0 μm), nanofibers demonstrated the highest ALP activity, indicating that ALP expression is inversely dependent on Rac1 activation. Knockdown of POR1 resulted in increased ALP activity across the substrates but without regard to the curvature sensing trend seen previously. Thus, POR1 senses curvature and increases Rac1 activity, which negatively regulates bone differentiation. PMID:25539497

  9. Substrate-specific modulation of CYP3A4 activity by genetic variants of cytochrome P450 oxidoreductase (POR)

    PubMed Central

    Agrawal, Vishal; Choi, Ji Ha; Giacomini, Kathleen M.; Miller, Walter L.

    2010-01-01

    Objectives CYP3A4 receives electrons from P450 oxidoreductase (POR) to metabolize about 50% of clinically used drugs. There is substantial inter-individual variation in CYP3A4 catalytic activity that is not explained by CYP3A4 genetic variants. CYP3A4 is flexible and distensible, permitting it to accommodate substrates varying in shape and size. To elucidate mechanisms of variability in CYP3A4 catalysis, we examined the effects of genetic variants of POR, and explored the possibility that substrate-induced conformational changes in CYP3A4 differentially affect the ability of POR variants to support catalysis. Methods We expressed human CYP3A4 and four POR variants (Q153R, A287P, R457H, A503V) in bacteria, reconstituted them in vitro and measured the Michaelis constant and maximum velocity with testosterone, midazolam, quinidine and erythromycin as substrates. Results POR A287P and R457H had low activity with all substrates; Q153R had 76–94% of wild type (WT) activity with midazolam and erythromycin, but 129–150% activity with testosterone and quinidine. The A503V polymorphism reduced CYP3A4 activity to 61–77% of wild type with testosterone and midazolam, but had nearly wild type activity with quinidine and erythromycin. Conclusion POR variants affect CYP3A4 activities. The impact of a POR variant on catalysis by CYP3A4 is substrate-specific, probably due to substrate-induced conformational changes in CYP3A4. PMID:20697309

  10. Intermitência alfvênica gerada por caos na atmosfera solar e no vento solar

    NASA Astrophysics Data System (ADS)

    Rempel, E. L.; Chian, A. C.-L.; Macau, E. E. N.; Rosa, R. R.

    2003-08-01

    Dados medidos no vento solar rápido proveniente dos buracos coronais revelam que os plasmas no meio interplanetário são dominados por flutuações Alfvênicas, caracterizadas por uma alta correlação entre as variações do campo magnético e da velocidade do plasma. As flutuações exibem muitas características esperadas em turbulência magneto-hidrodinâmica totalmente desenvolvida, tais como intermitência e espectros contínuos. Contudo, os mecanismos responsáveis pela evolução de turbulência Alfvênica intermitente não são completamente compreendidos. Neste trabalho a teoria de caos é usada para explicar como sistemas Alfvênicos, modelados pela equação Schrödinger não-linear derivativa e pela equação Kuramoto-Sivashinsky, podem se tornar fortemente caóticos à medida em que parâmetros do plasma são variados. Pequenas perturbações no parâmetro de dissipação podem fazer com que o sistema mude bruscamente de um regime periódico, ou fracamente caótico, para um regime fortemente caótico. As séries temporais das flutuações do campo magnético nos regimes fortemente caóticos exibem comportamento intermitente, em que fases laminares ou fracamente caóticas são interrompidas por fortes estouros caóticos. É mostrado que o regime fortemente caótico é atingido quando as soluções periódicas ou fracamente caóticas globalmente estáveis interagem com soluções do sistema que são fortemente caóticas, mas globalmente instáveis. Estas soluções globalmente instáveis são conjuntos caóticos não-atrativos conhecidos como selas caóticas, e são responsáveis pelos fortes estouros nos regimes intermitentes. Selas caóticas têm sido detectadas experimentalmente em uma grande variedade de sistemas, sendo provável que elas desempenhem um papel importante na turbulência intermitente observada em plasmas espaciais.

  11. Fabrication of por-Si/SnO{sub x} nanocomposite layers for gas microsensors and nanosensors

    SciTech Connect

    Bolotov, V. V. Korusenko, P. M.; Nesov, S. N.; Povoroznyuk, S. N.; Roslikov, V. E.; Kurdyukova, E. A.; Sten'kin, Yu. A.; Shelyagin, R. V.; Knyazev, E. V.; Kan, V. E.; Ponomareva, I. V.

    2011-05-15

    Two-phase nanocomposite layers based on porous silicon and nonstoichiometric tin oxide were fabricated by various methods. The structure, as well as elemental and phase composition, of the obtained nanocomposites were studied using transmission and scanning electron microscopy, Raman spectroscopy, Auger electron spectroscopy, and X-ray photoelectron spectroscopy. The results obtained confirm the formation of nanocomposite layers with a thickness as large as 2 {mu}m thick and SnO{sub x} stoichiometry coefficients x = 1.0-2.0. Significant tin diffusion into the porous silicon matrix with D{sub eff} Almost-Equal-To 10{sup -14} cm{sup 2} s{sup -1} was observed upon annealing at 770 K. Test sensor structures based on por-Si/SnO{sub x} nanocomposite layers grown by magnetron deposition showed fairly high stability of properties and sensitivity to NO{sub 2}.

  12. Recovery of naphthalene during evaporative concentration. [Tenax; XAD-2; POR-Q, XE-340

    SciTech Connect

    Higgins, C.E.; Guerin, M.R.

    1980-10-01

    The analysis of trace organics usually requires concentrating organic extracts to small volumes prior to instrumental analysis. The use of a concentration apparatus employing a nitrogen blanket and reduced pressure is desirable because the inert atmosphere and low temperature help to ensure stable composition. Unfortunately, diaromatic compounds such as the naphthalenes and biphenyls are frequently almost completely lost during the concentration step. Even under carefully controlled conditions only 26 +- 11% of the naphthalene is recovered. By placing a sorbent either in or downstream of the evaporation concentration flask, recovery of diaromatic compounds can be improved significantly. In this investigation, the following sorbents, Tenax, XAD-2, POR-Q, and XE-340 were tested. Recoveries with and without the use of sorbents, effects of solute concentration, purge time after solvent removal, and type of solvent used are reported here.

  13. Using the PORS Problems to Examine Evolutionary Optimization of Multiscale Systems

    SciTech Connect

    Reinhart, Zachary; Molian, Vaelan; Bryden, Kenneth

    2013-01-01

    Nearly all systems of practical interest are composed of parts assembled across multiple scales. For example, an agrodynamic system is composed of flora and fauna on one scale; soil types, slope, and water runoff on another scale; and management practice and yield on another scale. Or consider an advanced coal-fired power plant: combustion and pollutant formation occurs on one scale, the plant components on another scale, and the overall performance of the power system is measured on another. In spite of this, there are few practical tools for the optimization of multiscale systems. This paper examines multiscale optimization of systems composed of discrete elements using the plus-one-recall-store (PORS) problem as a test case or study problem for multiscale systems. From this study, it is found that by recognizing the constraints and patterns present in discrete multiscale systems, the solution time can be significantly reduced and much more complex problems can be optimized.

  14. Temperature trends and Urban Heat Island intensity mapping of the Las Vegas valley area

    NASA Astrophysics Data System (ADS)

    Black, Adam Leland

    Modified urban climate regions that are warmer than rural areas at night are referred to as Urban Heat Islands or UHI. Islands of warmer air over a city can be 12 degrees Celsius greater than the surrounding cooler air. The exponential growth in Las Vegas for the last two decades provides an opportunity to detect gradual temperature changes influenced by an increasing presence of urban materials. This thesis compares ground based thermometric observations and satellite based remote sensing temperature observations to identify temperature trends and UHI areas caused by urban development. Analysis of temperature trends between 2000 and 2010 at ground weather stations has revealed a general cooling trend in the Las Vegas region. Results show that urban development accompanied by increased vegetation has a cooling effect in arid climates. Analysis of long term temperature trends at McCarran and Nellis weather stations show 2.4 K and 1.2 K rise in temperature over the last 60 years. The ground weather station temperature data is related to the land surface temperature images from the Landsat Thematic Mapper to estimate and evaluate urban heat island intensity for Las Vegas. Results show that spatial and temporal trends of temperature are related to the gradual change in urban landcover. UHI are mainly observed at the airport and in the industrial areas. This research provides useful insight into the temporal behavior of the Las Vegas area.

  15. PERCHLORATE UPTAKE BY SALT CEDAR (TAMARIX RAMOSISSIMA) IN THE LAS VEGAS WASH RIPARIAN ECOSYSTEM

    EPA Science Inventory

    Perchlorate ion (CIO4-) has been identified in samples of dormant salt cedar (Tamarix ramosissima) growing in the Las vegas Wash. Perchlorate is an oxidenat, but its reduction is kineticaly hindered. CXoncern over thyrpoid effects caused the Environmental Protection Agency (EPA...

  16. 76 FR 61379 - Notice of Public Meeting, Las Cruces District Resource Advisory Council Meeting, New Mexico

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-04

    ... (FIRS) at 1-800-877-8229 to contact the above individual during normal business hours. The FIRS is available 24 hours a day, 7 days a week, to leave a message or question with the above individual. You will... concerns in the BLM Las Cruces District and future project work for the RAC. A half-hour public...

  17. The Development of Child Subjectivity in "La lengua de las mariposas"

    ERIC Educational Resources Information Center

    Ryan, Lorraine

    2012-01-01

    Jose Luis Cuerda's film "La lengua de las mariposas" is set in rural Galicia in the immediate lead-up to the outbreak of the Spanish Civil War. It portrays the tender relationship between a Republican schoolteacher, Don Gregorio, and a boy named Moncho. Upon the Nationalist capture of the town, the young Moncho hurls stones at his friend, but…

  18. Builders Challenge High Performance Builder Spotlight - NextGen Home, Las Vegas, Nevada

    SciTech Connect

    2009-01-01

    Building America Builders Challenge fact sheet on the NextGen demo home built in Las Vegas. The home has a Home Energy Rating System (HERS) index score of 44 with R-40 spray foam attic insulation, R-40 insulated concrete walls, and a 4kW DC solar laminate

  19. Twelve Years of Sociocultural Action in the Las Villas Area. Chapter 2.

    ERIC Educational Resources Information Center

    Gonzalez, Quintin Garcia

    This chapter reports on the activities of the Rural Continuing Education Centre (CREPA), a nongovernmental organization run by volunteers from small agricultural villages in the Las Villas area of Salamanca, Spain. The organization was founded in 1983 with the goal of improving living conditions and community life for villagers through social…

  20. Episodic Impacts from California Wildfires Identified in Las Vegas Near-Road Air Quality Monitoring

    EPA Science Inventory

    Air pollutant concentrations near major highways are usually attributed to a combination of nearby traffic emissions and regional background, and generally presumed to be additive in nature. During a recent year-long near-road monitoring study conducted in Las Vegas, NV, a substa...

  1. Perceptions toward the Value of Higher Education for Hotel Professionals in Las Vegas: A Case Study

    ERIC Educational Resources Information Center

    Deel, Gary Lee

    2015-01-01

    This study concerns a qualitative investigation of the views toward higher education and its importance to hospitality career success among hotel professionals in the Las Vegas, Nevada area. Existing literature supported the premise that education may be important to professional career success in several different ways, and that values concerning…

  2. Crustal structure in the vicinity of Las Vegas, Nevada, from seismic and gravity observations

    USGS Publications Warehouse

    Roller, John C.

    1963-01-01

    A seismic-refraction profile indicates that the crust of the Earth increases in thickness by as much as 5 km over a horizontal distance of less than 25 km northeast of Las Vegas, Nevada. This feature correlates with a decrease in the Bouguer anomaly and an increase in the average surface altitude.

  3. 77 FR 65332 - Proposed Modification of Class B Airspace; Las Vegas, NV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-26

    ... establishing the Las Vegas, NV, Terminal Control Area (TCA) with an effective date of November 11, 1974 (39 FR... to ensure that turbine-powered aircraft operations were fully contained within the TCA (47 FR 30052). In 1993, as part of the Airspace Reclassification Final Rule (56 FR 65638), the term...

  4. Changes in the morphometry of Las Vegas Wash and the impact on water quality

    USGS Publications Warehouse

    Roline, Richard A.; Sartoris, James J.

    1988-01-01

    Las Vegas Wash, a natural wash east of Las Vegas, Nevada, carries stormwater, groundwater drainage, and sewage effluent from two sewage treatment plants to Lake Mean. Over 80 percent of the normal discharge of approximately 3.4 m3/s (120 ft3/s) consists of effluent from the City of Las Vegas and Clark County sewage treatment plants. Beginning in the 1950s, a large wetland area developed along the wash that supported waterfowl populations and contributed to some water quality transformations. Heavy rains and subsequent flooding in the area in 1983 and 1984 resulted in erosion and channelization that greatly reduced the wetland area within Las Vegas Wash. The reduction in wetland area shortened water travel time in the wash and affected water quality. The primary impacts on the water entering Lake Mead have been an increase in temperature, a decrease in dissolved oxygen concentration, and an increase in ammonia levels. Other physical-chemical parameters and changes in nutrient transformations are also discussed.

  5. Control del dolor: Apoyo para las personas con cáncer

    Cancer.gov

    Contiene información sobre las medicinas contra el dolor para pacientes con cáncer, los planes para controlarlo, cómo hablar con su equipo de atención médica sobre el dolor que usted siente y qué hacer para controlar los efectos físicos y emocionales del

  6. 76 FR 35371 - Proposed Modification of the Las Vegas, NV, Class B Airspace Area; Public Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-17

    ...: (1) The meeting on Thursday, August 18, 2011, will be held at Centennial High School, 10200... Coronado High School, 10 1 Coronado Center Drive, Henderson, NV 89052; (3) The meeting on Thursday, August 25, 2011, will be held at Shadow Ridge High School, 5050 Brent Lane, Las Vegas, NV 89131....

  7. LAS VEGAS VALLEY WATER BUDGET: RELATIONSHIP OF DISTRIBUTION, CONSUMPTIVE USE, AND RECHARGE TO SHALLOW GROUND WATER

    EPA Science Inventory

    Estimates of quantity and geographic distribution of recharge to the shallow ground-water zone from water use return flows in Las Vegas Valley were made for the years 1973, 1965, 1958, 1950, and 1943 as part of a broader study on the impact of water and land use on ground-water q...

  8. LAND AND WATER USE EFFECTS ON GROUND-WATER QUALITY IN LAS VEGAS VALLEY

    EPA Science Inventory

    The hydrogeologic study of the shallow ground-water zone in Las Vegas Valley, Nevada determined the sources and extent of ground-water contamination to develop management alternatives and minimize adverse effects. An extensive, computerized data base utilizing water analyses, wel...

  9. METHODOLOGY FOR DESIGNING AIR QUALITY MONITORING NETWORKS: 2. APPLICATION TO LAS VEGAS, NEVADA, FOR CARBON MONOXIDE

    EPA Science Inventory

    An objective methodology presented in a companion paper (Liu et al., 1986) for determining the optimum number and disposition of ambient air quality stations in a monitoring network for carbon monoxide is applied to the Las Vegas, Nevada, area. The methodology utilizes an air qua...

  10. Builders Challenge High Performance Builder Spotlight - Masco Environments for Living, Las Vegas, Nevada

    SciTech Connect

    2009-01-01

    Building America Builders Challenge fact sheet on Masco’s Environments for Living Certified Green demo home at the 2009 International Builders Show in Las Vegas. The home has a Home Energy Rating System (HERS) index score of 44, a right-sized air conditi

  11. Las Cruces Public Schools: A View of Our Schools, 1986-87 School Year.

    ERIC Educational Resources Information Center

    Cavatta, Jerry C.

    Las Cruces Public Schools (Dona Ana County, New Mexico) is the second largest school district in New Mexico serving 6% of the state's public school students. Enrollment, declining in the late 1970s to a 1980-81 low of 15,349 students, has increased steadily through the 1986-87 school year, when 17,207 students were enrolled, primarily in grades…

  12. 78 FR 2646 - Proposed Modification of Class B Airspace; Las Vegas, NV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-14

    ... that was published on October 26, 2012. In that document, the FAA proposed to modify the Las Vegas, NV... FR 65332) closed on December 26, 2012, is reopened until February 13, 2013. ADDRESSES: Send comments... particularly helpful in developing reasoned regulatory decisions on the proposal. Comments are...

  13. 75 FR 38778 - Expansion of Foreign-Trade Zone 89 Las Vegas, NV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ... the Federal Register (74 FR 59131-59132, 11/17/09) and the application has been processed pursuant to... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Expansion of Foreign-Trade Zone 89 Las Vegas, NV Pursuant to its authority...

  14. Magnetostratigraphy of the Miocene Las Arcas Formation, Santa María Valley, northwestern Argentina

    NASA Astrophysics Data System (ADS)

    Spagnuolo, Cecilia M.; Georgieff, Sergio M.; Rapalini, Augusto E.

    2015-11-01

    The first magnetostratigraphic study of the Las Arcas Formation (Late Miocene) was carried out in Las Totoritas creek (26º12‧S; 65º47‧W, NW Argentina), a key place in between of two geological provinces: Northwestern Pampean Ranges and Eastern Cordillera, in northwestern Argentina. This was accompanied by isotopic dating (9.01 ± 0.12 Ma, 40Ar-39Ar in amphibole) of the unit, obtained from a 3.4 m thick tuff intercalated at ˜45 m above the base. The Las Arcas Formation is 810 m thick at the sampling locality and it is mainly composed of tabular reddish conglomerates, sandstones and siltstones in both coarsening- and thickening-upward arrangements. The exposed section was sampled at 48 sites, 26 of which are interpreted as carrying primary magnetization. The new magnetostratigraphic column was correlated with the Geomagnetic Polarity Time Scale (GPTS), and suggests that deposition of the Las Arcas Formation strata started at around 9.1 Ma and ended around 6.8 Ma. The paleomagnetic pole obtained for this unit (Dec = 8.7° Inc = -43.9° dp = 14.9 dm 9.3) indicates that this area underwent non-significant rotation (11.0° ± 13.6°) since the Late Miocene.

  15. Effect of linear alkylbenzene sulfonate (LAS) on human intestinal Caco-2 cells at non cytotoxic concentrations.

    PubMed

    Bradai, Mohamed; Han, Junkyu; Omri, Abdelfatteh El; Funamizu, Naoyuki; Sayadi, Sami; Isoda, Hiroko

    2016-08-01

    Linear alkylbenzene sulfonate (LAS) is a cytotoxic synthetic anionic surfactant widely present in the environment due to its large-scale production and intensive use in the detergency field. In this study, we investigated the effect of LAS (CAS No. 25155-30-0) at non cytotoxic concentrations on human intestinal Caco-2 cells using different in vitro bioassays. As results, LAS increased Caco-2 cell proliferation at concentrations ranging from 1 to 15 ppm, more significantly for shorter exposure time (24 h), confirmed using flow cytometry and trypan blue exclusion methods. Moreover, proteomics analysis revealed that this effect was associated with an over-expression of elongation factor 2 and dipeptidyl peptidase 3, and a down-regulation of 14-3-3 protein theta, confirmed at mRNA level using real-time PCR. These findings suggest that LAS at non cytotoxic concentrations, similar to those observed at wastewater treatment plants outlets, increases the growth rate of colon cancer cells, raising thereby its tumor promotion effect potential. PMID:25999174

  16. Orion Launch Abort System (LAS) Propulsion on Pad Abort 1 (PA-1)

    NASA Technical Reports Server (NTRS)

    Jones, Daniel S.

    2015-01-01

    This presentation provides a concise overview of the highly successful Orion Pad Abort 1 (PA-1) flight test, and the three rocket motors that contributed to this success. The primary purpose of the Orion PA-1 flight was to help certify the Orion Launch Abort System (LAS), which can be utilized in the unlikely event of an emergency on the launchpad or during mission vehicle ascent. The PA-1 test was the first fully integrated flight test of the Orion LAS, one of the primary systems within the Orion Multi-Purpose Crew Vehicle (MPCV). The Orion MPCV is part of the architecture within the Space Launch System (SLS), which is being designed to transport astronauts beyond low-Earth orbit for future exploration missions. Had the Orion PA-1 flight abort occurred during launch preparations for a real human spaceflight mission, the PA-1 LAS would have saved the lives of the crew. The PA-1 flight test was largely successful due to the three solid rocket motors of the LAS: the Attitude Control Motor (ACM); the Jettison Motor (JM); and the Abort Motor (AM). All three rocket motors successfully performed their required functions during the Orion PA-1 flight test, flown on May 6, 2010 at the White Sands Missile Range in New Mexico, culminating in a successful demonstration of an abort capability from the launchpad.

  17. PROCEEDINGS: SYMPOSIUM ON FLUE GAS DESULFURIZATION HELD AT LAS VEGAS, NEVADA, MARCH 1979; VOLUME II

    EPA Science Inventory

    The publication, in two volumes, contains the text of all papers presented at EPA's fifth flue gas desulfurization (FGD) symposium, March 5-8, 1979, at Las Vegas, Nevada. A partial listing of papers in Volume 2 includes the following: Basin Electric's involvement with dry flue ga...

  18. 76 FR 37034 - Proposed Modification of the Las Vegas, NV, Class B Airspace Area; Public Meetings; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ... of June 17, 2011, in FR Doc. 2011-15107, on page 35371, column 3, correct meeting number (2) in the... Federal Aviation Administration 14 CFR Part 71 Proposed Modification of the Las Vegas, NV, Class B... of June 17, 2011, concerning a proposal to modify Class B airspace at Las Vegas, NV. The...

  19. 76 FR 3678 - Board Meeting: February 16, 2011-Las Vegas, NV, the U.S. Nuclear Waste Technical Review Board...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-20

    ... REVIEW BOARD Board Meeting: February 16, 2011--Las Vegas, NV, the U.S. Nuclear Waste Technical Review... Amendments Act of 1987, the U.S. Nuclear Waste Technical Review Board will meet in Las Vegas, Nevada, on... review current DOE activities related to implementation of the Nuclear Waste Policy Act. The...

  20. Las1 interacts with Grc3 polynucleotide kinase and is required for ribosome synthesis in Saccharomyces cerevisiae

    PubMed Central

    Castle, Christopher D.; Sardana, Richa; Dandekar, Varada; Borgianini, Victoria; Johnson, Arlen W.; Denicourt, Catherine

    2013-01-01

    Ribosome biogenesis is a multi-step process that couples cell growth with cell proliferation. Although several large-scale analysis of pre-ribosomal particles have identified numerous trans-acting factors involved in this process, many proteins involved in pre-rRNA processing and ribosomal subunit maturation have yet to be identified. Las1 was originally identified in Saccharomyces cerevisiae as a protein involved in cell morphogenesis. We previously demonstrated that the human homolog, Las1L, is required for efficient ITS2 rRNA processing and synthesis of the 60S ribosomal subunit. Here, we report that the functions of Las1 in ribosome biogenesis are also conserved in S. cerevisiae. Depletion of Las1 led to the accumulation of both the 27S and 7S rRNA intermediates and impaired the synthesis of the 60S subunit. We show that Las1 co-precipitates mainly with the 27S rRNA and associates with an Nsa1 and Rix1-containing pre-60S particle. We further identify Grc3 as a major Las1-interacting protein. We demonstrate that the kinase activity of Grc3 is required for efficient pre-rRNA processing and that depletion of Grc3 leads to rRNA processing defects similar to the ones observed in Las1-depleted cells. We propose that Las1 and Grc3 function together in a conserved mechanism to modulate rRNA processing and eukaryotic ribosome biogenesis. PMID:23175604

  1. Display of a PorA peptide from Neisseria meningitidis on the bacteriophage T4 capsid surface.

    PubMed Central

    Jiang, J; Abu-Shilbayeh, L; Rao, V B

    1997-01-01

    The exterior of bacteriophage T4 capsid is coated with two outer capsid proteins, Hoc (highly antigenic outer capsid protein; molecular mass, 40 kDa) and Soc (small outer capsid protein; molecular mass, 9 kDa), at symmetrical positions on the icosahedron (160 copies of Hoc and 960 copies of Soc per capsid particle). Both these proteins are nonessential for phage infectivity and viability and assemble onto the capsid surface after completion of capsid assembly. We developed a phage display system which allowed in-frame fusions of foreign DNA at a unique cloning site in the 5' end of hoc or soc. A DNA fragment corresponding to the 36-amino-acid PorA peptide from Neisseria meningitidis was cloned into the display vectors to generate fusions at the N terminus of Hoc or Soc. The PorA-Hoc and PorA-Soc fusion proteins retained the ability to bind to the capsid surface, and the bound peptide was displayed in an accessible form as shown by its reactivity with specific monoclonal antibodies in an enzyme-linked immunosorbent assay. By employing T4 genetic strategies, we show that more than one subtype-specific PorA peptide can be displayed on the capsid surface and that the peptide can also be displayed on a DNA-free empty capsid. Both the PorA-Hoc and PorA-Soc recombinant phages are highly immunogenic in mice and elicit strong antipeptide antibody titers even with a weak adjuvant such as Alhydrogel or no adjuvant at all. The data suggest that the phage T4 hoc-soc system is an attractive system for display of peptides on an icosahedral capsid surface and may emerge as a powerful system for construction of the next generation multicomponent vaccines. PMID:9353063

  2. Bioconcentration and toxicity of dodecylbenzene sulfonate (C12LAS) to aquatic organisms exposed in experimental streams.

    PubMed

    Versteeg, D J; Rawlings, J M

    2003-02-01

    Fish, mollusks, and crustaceans were caged in the tail pool of streams during a C(12)LAS (dodecyl benzene sulfonate) model ecosystem experimental program. Bioconcentration of total C(12)LAS and individual isomers and acute and chronic toxicity were investigated during this study. Toxicity endpoints were based on water and tissue (i.e., body burden) concentrations at which adverse effects were observed. At 32 days, total C(12)LAS bioconcentration factors (BCFs) for the fathead minnow and three invertebrate species ranged from 9 to 116. In general, bioconcentration was affected by isomer position, exposure concentration, and species. BCF values tended to decrease as isomer position moved from external (e.g., 2-phenyl) to internal (e.g., 5,6-phenyl). BCFs also decreased as exposure concentration increased. Mean acute 4-d LC(50) values ranged from 1.5 to >3.0 mg/L for the six species tested. Lethal body burdens associated with 50% mortality (LBB(50)) varied from 0.21 to 0.60 mmole/kg (wet weight). During the 32-day chronic exposures, the EC(20) values were 0.27 (0.204-0.352), 0.95 (0.597-1.29), and approximately 1.0 mg/L for Corbicula (length), Hyalella (survival), and fathead minnow (survival), respectively. At these EC(20) values, C(12)LAS body burdens were 0.035, 0.23, and 0.19 mmoles/kg wet weight in Corbicula, Hyalella, and fathead minnow, respectively. Fish exposed to wastewater treatment plant effluent had total C(12)LAS tissue concentrations ranging from 0.0005 to 0.0039 mmoles/kg wet weight. These concentrations are approximately 45-360 times below the tissue concentration associated with subtle effects in the model ecosystem stream exposures. Total C(12)LAS body burdens in feral and caged Corbicula exposed to WWTP effluents were approximately 0.0013 mmoles/kg; approximately 25-fold below concentrations associated with effects in stream exposures. PMID:12520396

  3. High School Students' Previous Knowledge about the Stars. (Spanish Title: Conocimientos Previos de Estudiantes de Secundaria Acerca de Las Estrellas.) O Conhecimento Prévio de Alunos do Ensino Médio sobre as Estrelas

    NASA Astrophysics Data System (ADS)

    Iachel, Gustavo

    2011-12-01

    Based on the readings of articles related to Astronomy Education published in Brazil, it was noticed a lack of research on previous knowledge of students about the physical characteristics of stars, a fact that motivated us to develop this study. Previous knowledge of 125 students (approximated 15 years old) constituted the study sample; data was collected through written questionnaires (Appendix A) for analysis. From the content analysis of these responses it was possible to achieve some inferences as, for example, many students have some difficult to develop an explanatory model on the functioning of a star; there are few who say that the stars have a certain length of existence; some students have said that stars have tips; few recognize that a star is formed by a mass of gas; some previous knowledge come from purely visual aspects; furthermore, some students do not have the habit of observing nature in detail. We see this research as a reference in which science teachers can recognize the importance of previous knowledge for practice teaching and acquire resources for planning their lessons. De la lectura de artículos relacionados con la Educación en Astronomía publicados en el Brasil, se encuentra una falta de investigaciones acerca del conocimiento previo de los estudiantes sobre las características físicas de las estrellas, hecho que nos motivó a desarrollar este estudio. Los datos analizados se obtuvieron al aplicar un cuestionario a 125 estudiantes de secundaria, para posteriormente realizar un análisis de contenido, tal cuestionario se presenta en el Anexo A. Al realizar el análisis de contenido de las respuestas obtenidas, fue posible hacer algunas inferencias, como por ejemplo; muchos estudiantes tienen dificultades para desarrollar un modelo explicativo acerca del funcionamiento de una estrella; pocos estudiantes dicen que las estrellas tienen un cierto tiempo de vida; algunos estudiantes imaginan que las estrellas tienen puntas; pocos

  4. Rescue of cytochrome P450 oxidoreductase (Por) mouse mutants reveals functions in vasculogenesis, brain and limb patterning linked to retinoic acid homeostasis.

    PubMed

    Ribes, Vanessa; Otto, Diana M E; Dickmann, Leslie; Schmidt, Katy; Schuhbaur, Brigitte; Henderson, Colin; Blomhoff, Rune; Wolf, C Roland; Tickle, Cheryll; Dollé, Pascal

    2007-03-01

    Cytochrome P450 oxidoreductase (POR) acts as an electron donor for all cytochrome P450 enzymes. Knockout mouse Por(-/-) mutants, which are early embryonic (E9.5) lethal, have been found to have overall elevated retinoic acid (RA) levels, leading to the idea that POR early developmental function is mainly linked to the activity of the CYP26 RA-metabolizing enzymes (Otto et al., Mol. Cell. Biol. 23, 6103-6116). By crossing Por mutants with a RA-reporter lacZ transgene, we show that Por(-/-) embryos exhibit both elevated and ectopic RA signaling activity e.g. in cephalic and caudal tissues. Two strategies were used to functionally demonstrate that decreasing retinoid levels can reverse Por(-/-) phenotypic defects, (i) by culturing Por(-/-) embryos in defined serum-free medium, and (ii) by generating compound mutants defective in RA synthesis due to haploinsufficiency of the retinaldehyde dehydrogenase 2 (Raldh2) gene. Both approaches clearly improved the Por(-/-) early phenotype, the latter allowing mutants to be recovered up until E13.5. Abnormal brain patterning, with posteriorization of hindbrain cell fates and defective mid- and forebrain development and vascular defects were rescued in E9.5 Por(-/-) embryos. E13.5 Por(-/-); Raldh2(+/-) embryos exhibited abdominal/caudal and limb defects that strikingly phenocopy those of Cyp26a1(-/-) and Cyp26b1(-/-) mutants, respectively. Por(-/-); Raldh2(+/-) limb buds were truncated and proximalized and the anterior-posterior patterning system was not established. Thus, POR function is indispensable for the proper regulation of RA levels and tissue distribution not only during early embryonic development but also in later morphogenesis and molecular patterning of the brain, abdominal/caudal region and limbs. PMID:17126317

  5. The Impact of Regional Differences on Elementary School Teachers' Attitudes towards Their Students' Use of Code Switching in a South Texas School District (El impacto de las diferencias regionales en las actitudes de docentes de primaria respecto a la alternancia de códigos por parte de los estudiantes en un distrito escolar del sur de Texas)

    ERIC Educational Resources Information Center

    Nava Gómez, Guadalupe Nancy; García, Hilda

    2012-01-01

    This study focused on investigating whether the teachers' geographical distribution influences their attitudes towards their students' use of code switching. The study was guided by the following research question: Are there differences between teachers' opinions of the north elementary schools and teachers' opinions of the…

  6. Los Hispanos: Problemas y Oportunidades. Resumen de la Actual Situacion Demografica, Economica, Social y Politica de los Hispanos en los Estados Unidos y de las Iniciativas Tomadas por la Fundacion Ford Para Hacer Frente a las Necesidades de esta Poblacion en Aumento y Determinar sus Efectos Sobre la Sociedad Estadounidense. Documento de Trabajo de la Fundacion Ford, No. 436.

    ERIC Educational Resources Information Center

    Ford Foundation, New York, NY.

    The Hispanic population's growing impact on American society has caused the Ford Foundation to explore new Foundation initiatives. The 1980 census revealed 14.6 million Hispanics: 60% Mexican American; 14% Puerto Rican; 6% Cuban, and 20% Other. The Hispanic population in the United States is growing and is characterized by diversity; rapid growth…

  7. Functional POR A503V is associated with the risk of bladder cancer in a Chinese population

    PubMed Central

    Xiao, Xue; Ma, Gaoxiang; Li, Shushu; Wang, Meilin; Liu, Nian; Ma, Lan; Zhang, Zhan; Chu, Haiyan; Zhang, Zhengdong; Wang, Shou-Lin

    2015-01-01

    Human cytochrome P450 oxidoreductase (POR) plays important roles in the metabolism of exogenous carcinogens and endogenous sterol hormones. However, few studies have explored the association between POR variants and the risk of bladder cancer. In this study, we first sequenced all 16 POR exons among 50 randomly selected controls, and found three variants, rs1135612, rs1057868 (A503V) and rs2228104, which were then assessed the relation to risk of bladder cancer in a case-control study of 1,050 bladder cancer cases and 1,404 cancer-free controls in a Chinese population. People with A503V TT genotype have a decreased risk of bladder cancer in a recessive model (TT vs. CC/CT, OR = 0.73, 95% CI = 0.57–0.93), which was more pronounced among elderly male, non-smoking, subjects. Especially, A503V TT genotype showed a protective effect in the invasive tumor stage. Functional analysis revealed that A503V activity decreased in cytochrome c reduction (50.5 units/mg vs. 135.4 units/mg), mitomycin C clearance (38.3% vs. 96.8%), and mitomycin C-induced colony formation (78.0 vs 34.3 colonies per dish). The results suggested that POR A503V might decrease the risk of bladder cancer by reducing its metabolic activity, and should be a potential biomarker for predicting the susceptibility to human bladder cancer. PMID:26123203

  8. Global Microlending in Education Reform: Enseñá Por Argentina and the Neoliberalization of the Grassroots

    ERIC Educational Resources Information Center

    Friedrich, Daniel S.

    2010-01-01

    This article examines the workings and underlying assumptions behind Enseñá por Argentina (Teach for Argentina), one specific program that takes part in the larger and expanding network of Teach for All, by thinking about the ways in which a global push for redefining teaching and teacher education encounters local characteristics and histories,…

  9. [Professor Frantisek Por MD and Professor Robert Klopstock MD, students at Budapest and Prague Faculties of Medicine].

    PubMed

    Mydlík, M; Derzsiová, K

    2010-11-01

    Professor Frantisek Por MD and Professor Robert Klopstock MD were contemporaries, both born in 1899, one in Zvolen, the other in Dombovar, at the time of Austro-Hungarian Monarchy. Prof. Por attended the Faculty of Medicine in Budapest from 1918 to 1920, and Prof. Klopstock studied at the same place between 1917 and 1919. From 1920 until graduation on 6th February 1926, Prof. Por continued his studies at the German Faculty of Medicine, Charles University in Prague. Prof. Klopstock had to interrupt his studies in Budapest due to pulmonary tuberculosis; he received treatment at Tatranske Matliare where he befriended Franz Kafka. Later, upon Kafka's encouragement, he changed institutions and continued his studies at the German Faculty of Medicine, Charles University in Prague, where he graduated the first great go. It is very likely that, during their studies in Budapest and Prague, both professors met repeatedly, even though their life paths later separated. Following his graduation, Prof. Por practiced as an internist in Prague, later in Slovakia, and from 1945 in Kosice. In 1961, he was awarded the title of university professor of internal medicine at the Faculty of Medicine, Pavol Jozef Safarik University in Kosice, where he practiced until his death in 1980. Prof. Klopstock continued his studies in Kiel and Berlin. After his graduation in 1933, he practiced in Berlin as a surgeon and in 1938 left for USA. In 1962, he was awarded the title of university professor of pulmonary surgery in NewYork, where he died in 1972. PMID:21250499

  10. Geologic Interpretation of the Las Vegas Valley Based on Industry Seismic Reflection Data

    NASA Astrophysics Data System (ADS)

    Hirsch, A.; Snelson, C. M.

    2003-12-01

    Las Vegas Valley, NV is located in the southern Basin and Range Province where the basin was formed by the Las Vegas Valley Shear Zone as well as by several thrust and normal faulting events that occurred by Cenozoic time. The geology and tectonic setting in the Las Vegas region is poorly understood given the fact that many structures have been covered by the constant growth of the City. National studies of ground motion and amplification of seismic energy placed Nevada third in the list of states having the potential for loss of life and property due to earthquakes. The Las Vegas area has a high potential for strong ground shaking due its thick basin fill and associated amplification. Due to the amplification effects within the Valley, moderate nearby quakes or large distant quakes will produce a large amount of damage in the Valley. Las Vegas, though not known for its earthquakes, has numerous micro quakes and an active seismic history. In a study using HAZUS to predict damage associated with a M6.9 earthquake, the loss would be billions of dollars with thousands of lives lost. Long-term economic loss would be in the several billions of dollars. Recently, several normal faults, which have the potential to produce a M6.5 to 7.0 earthquake, were reclassified as active tectonic fault with Quaternary movement. As a result, there has been increased effort to understand the Las Vegas Valley and to assess its potential for seismic hazards. One such effort included acquiring industry reflection profiles that cross the Valley. In the 1980's, north/south and east/west trending reflection lines with intersecting tie points were placed between Frenchman Mountain to the East and Spring Mountains to produce seismic profiles using Vibroseis. The profiles, which are over 200 kilometers in length and extend down to 5 s in time or approximately 15 km depth, will provide a tie between the surface work that is currently being conducted and the crustal velocity models that are being

  11. [History of the discovery of the Lasègue phenomenon and its variants].

    PubMed

    Karbowski, K

    1984-07-10

    Ernest Charles Lasègue (1816-1883) discovered, but did not describe himself, the straight-leg-raising sign. This sign was described by one of this disciples, J.-J. Forst, in a doctoral thesis in Paris in 1881. Almost at the same time, L.K. Lazarević in Belgrade dealt with the same subject. The crossed-sciatic phenomenon was described for the first time by a Polish neurologist, J. Fajersztajn. In the same publication he mentioned the possibility of the activation of sciatica as a result of dorsiflexion of the foot. Independently of Fajersztajn, the Genevan specialist for internal medicine, Maurice Roch, observed the same phenomenon and called it "Lasègue du pied". The eponym "Bragard sign" for this manoeuvre is not correct. PMID:6382594

  12. Reinterpretation of the stratigraphy and structure of the Rancho Las Norias area, central Sonora, Mexico

    USGS Publications Warehouse

    Page, W.R.; Harris, A.G.; Poole, F.G.; Repetski, J.E.

    2003-01-01

    New geologic mapping and fossil data in the vicinity of Rancho Las Norias, 30 km east of Hermosillo, Sonora, Mexico, show that rocks previously mapped as Precambrian instead are Paleozoic. Previous geologic maps of the Rancho Las Norias area show northeast-directed, southwest-dipping reverse or thrust faults deforming both Precambrian and Paleozoic rocks. The revised stratigraphy requires reinterpretation of some of these faults as high-angle normal or oblique-slip faults and the elimination of other faults. We agree with earlier geologic map interpretations that compressional structures have affected the Paleozoic rocks in the area, but our mapping suggests that the direction of compression is from southeast to northwest. Published by Elsevier Ltd.

  13. Structure and tensile strength of LaS(1.4)

    NASA Technical Reports Server (NTRS)

    Whittenberger, J. Daniel; Smoak, Richard H.

    1987-01-01

    The tensile strength of LaS(1.4) has been estimated by diametral stress testing at room temperature, 800 and 1300 K. Brittle, tensile-type failures were obtained at all temperatures when the crosshead speed was 0.0021 mm/s; however, a 1300 K test at 0.00085 mm/s produced plastic flow. The microstructure of LaS(1.4) consisted of two phases with beta-La2S3 comprising about 15 vol percent of the structure and gamma-La2S3 the remainder. Because of the limited amount of material available for testing, no correlation between microstructure and mechanical strength could be drawn.

  14. Reinterpretation of the stratigraphy and structure of the Rancho Las Norias area, central Sonora, Mexico

    NASA Astrophysics Data System (ADS)

    Page, William R.; Harris, Anita G.; Poole, Forrest G.; Repetski, John E.

    2003-12-01

    New geologic mapping and fossil data in the vicinity of Rancho Las Norias, 30 km east of Hermosillo, Sonora, Mexico, show that rocks previously mapped as Precambrian instead are Paleozoic. Previous geologic maps of the Rancho Las Norias area show northeast-directed, southwest-dipping reverse or thrust faults deforming both Precambrian and Paleozoic rocks. The revised stratigraphy requires reinterpretation of some of these faults as high-angle normal or oblique-slip faults and the elimination of other faults. We agree with earlier geologic map interpretations that compressional structures have affected the Paleozoic rocks in the area, but our mapping suggests that the direction of compression is from southeast to northwest.

  15. Solar hot water system installed at Las Vegas, Nevada. Final report

    SciTech Connect

    1981-01-01

    The solar hot water system installed at LaQuinta Motor Inn Inc., at Las Vegas, Nevada is described. The Inn is a three-story building with a flat roof for installation of the solar panels. The system consists of 1200 square feet of liquid flat plate collectors, a 2500 gallon insulated vertical steel storage tank, two heat exchangers and pumps and controls. The system was designed to supply approximately 74 percent of the total hot water load.

  16. Comenditic and pantelleritic ash-flow tuffs from Volcan Las Navajas, Nayarit, Mexico

    SciTech Connect

    Nelson, S.A.; Hebre, J.A.

    1985-01-01

    Two distinctive ash-flow tuffs occur around the base of Volcan Las Navajas, a Pleistocene trachyte - peralkaline rhyolite center located in the northwestern segment of the Mexican Volcanic belt. The lower ash-flow unit is locally up to 65 m thick, is lithic rich and contains pumice blocks of comenditic rhyolite. The unit is not extensively exposed, and thus its areal extent and volume cannot be determined. Its chemical characteristics and stratigraphic relationship to other products erupted from Las Navajas suggest that it is related to the formation of the older of the two calderas which occur on Las Navajas. Unconformably overlying this unwelded ash-flow is a pantelleritic airfall pumice unit which is locally welded. This airfall unit is conformably overlain by a welded as-flow tuff that contains fiamme of pantelleritic composition (72 %SiO/sub 2/, 8% FeO*, 900 ppm Zr, agpaitic index of 1.7) as well as pumice blocks that show evidence of various degrees of mixing between pantellerite and trachyte. This suggests eruption from a chemically zoned magma chamber. This unit is locally up to 20 m thick, although its top has been removed by erosion. It is found on all sides of Las Navajas except on the south where it may be covered by Volcan Sanganguey, a Pleistocene to Recent calc-alkaline volcano. The welded ash-flow has been dated by K - Ar at 0.2+/-0.1 m.y. Stratigraphically and chemically this ash-flow appears to be related to the formation of younger of the two calderas.

  17. LANDSAT-D project ADDS/LAS. Scrounge interface control document

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The content and format of all data to be exchanged between the Applications Developmental data System (ADDS) and the LANDSAT-D Assessment System (LAS) for satisfaction of early access thematic mapper product generation requirements is specified. The ADDS provides partially processed TM data tapes on CCT's. The LANDSAT-D Assessment System processes the TM data to fully processed data tapes on 6250 bpi computer compatible tapes and provides required film data products.

  18. 40 CFR 51.917 - What is the effective date of designation for the Las Vegas, NV, 8-hour ozone nonattainment area?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... designation for the Las Vegas, NV, 8-hour ozone nonattainment area? 51.917 Section 51.917 Protection of... Air Quality Standard § 51.917 What is the effective date of designation for the Las Vegas, NV, 8-hour ozone nonattainment area? The Las Vegas, NV, 8-hour ozone nonattainment area (designated on September...

  19. 40 CFR 51.917 - What is the effective date of designation for the Las Vegas, NV, 8-hour ozone nonattainment area?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... designation for the Las Vegas, NV, 8-hour ozone nonattainment area? 51.917 Section 51.917 Protection of... Air Quality Standard § 51.917 What is the effective date of designation for the Las Vegas, NV, 8-hour ozone nonattainment area? The Las Vegas, NV, 8-hour ozone nonattainment area (designated on September...

  20. 40 CFR 51.917 - What is the effective date of designation for the Las Vegas, NV, 8-hour ozone nonattainment area?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... designation for the Las Vegas, NV, 8-hour ozone nonattainment area? 51.917 Section 51.917 Protection of... Air Quality Standard § 51.917 What is the effective date of designation for the Las Vegas, NV, 8-hour ozone nonattainment area? The Las Vegas, NV, 8-hour ozone nonattainment area (designated on September...

  1. 40 CFR 51.917 - What is the effective date of designation for the Las Vegas, NV, 8-hour ozone nonattainment area?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... designation for the Las Vegas, NV, 8-hour ozone nonattainment area? 51.917 Section 51.917 Protection of... Air Quality Standard § 51.917 What is the effective date of designation for the Las Vegas, NV, 8-hour ozone nonattainment area? The Las Vegas, NV, 8-hour ozone nonattainment area (designated on September...

  2. Effect of acclimation to outdoor condition on the sexual performance of mass-produced Medflies (Diptera: Tephritidae)

    SciTech Connect

    Pereira, R.; Silva, N.; Quintal, C.; Abreu, R.; Andrade, J.; Dantas, L.

    2007-03-15

    Application of the sterile insect technique (SIT) as part of integrated area-wide programs to control the Mediterranean fruit fly (medfly) Ceratitis capitata (Wiedemann) require that the released males attract wild females and transfer sterile sperm. However, knowledge about male sexual performance after they are released is scarce. We conducted a study to evaluate male sexual performance in field cage tests, according to standard quality control procedures. Mass-reared 5-d-old sterile males from the genetic sexing strain VIENNA 7mix2000 were acclimated for 0, 1, and 3 d to outdoor conditions before competing with wild males for wild females. Although the proportion of mating (PM) in the test was satisfactory, the resulting relative sterility index (RSI) data showed no significant differences among the treatments. The data indicate that pre-conditioning males to outdoor conditions in Madeira did not confer an advantage in field cage sexual performance. (author) [Spanish] La aplicacion de la tecnica del insecto esteril (TIE) como parte de un programa integrado de amplio efecto para el control de la mosca mediterranea de la fruta Ceratitis capitata (Wiedemann) requiere que los machos liberados atraigan las hembras naturales y transfieran su esperma. Sin embargo, el conocimiento del desempeno sexual de los machos despues de ser liberados es muy escaso. Nosotros realizamos un estudio para evaluar el desempeno sexual de los machos en pruebas usando jaulas del campo, segun los procedimientos estandardizados de calidad. Machos esteriles de 5 dias de edad de la raza que separa los sexos geneticamente VIENNA 7mix2000 criados en masa fueron aclimatados por 0, 1 y 3 dias en condiciones de campo antes de competir con machos naturales para las hembras naturales. Aunque la proporcion del apareamiento en la prueba fue satisfactorio, el indice relativo de esterilidad (IRS) resultante no mostro ninguna diferencia significativa entre los tratamientos. Los datos indicaron que al

  3. Surficial geology and distribution of post-impoundment sediment in Las Vegas Bay, Lake Mead

    USGS Publications Warehouse

    Twichell, David C.; Cross, VeeAnn A.; Rudin, Mark J.; Parolski, Kenneth F.; Rendigs, Richard R.

    2001-01-01

    Sidescan sonar imagery and seismic-reflection profiles were collected in the northwestern part of Las Vegas Bay to map the distribution and volume of sediment that has accumulated in this part of Lake Mead since impoundment. The mapping suggests that three ephemeral streams are the primary source of this sediment, and of these, Las Vegas Wash is the largest. Two deltas off the mouth of Las Vegas Wash formed at different lake elevations and account for 41% of the total volume of post-impoundment sediment within the study area. Deltas off the other two washes (Gypsum and Government) account for only 6% of the total volume. The sediment beyond the front of the deltas is primarily mud, and it only occurs in valley floors, where it forms a flat-lying blanket that is mostly less than 1.5 m thick. Although a thin layer, the fine-grained sediment accounts for approximately 53% of the total post-impoundment sediment volume of 5.7 x 106 m3 that has accumulated in the study area. This sediment appears to have been transported several kilometers from the river sources by density flows.

  4. Quantifying multi-temporal urban development characteristics in Las Vegas from Landsat and ASTER data

    USGS Publications Warehouse

    Xian, G.; Crane, M.; McMahon, C.

    2008-01-01

    Urban development has expanded rapidly in Las Vegas, Nevada of the United States, over the last fifty years. A major environmental change associated with this urbanization trend is the transformation of the landscape from natural cover types to increasingly anthropogenic impervious surface. This research utilizes remote sensing data from both the Landsat and Terra-Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) instruments in conjunction with digital orthophotography to estimate urban extent and its temporal changes by determining sub-pixel impervious surfaces. Percent impervious surface area has shown encouraging agreement with urban land extent and development density. Results indicate that total urban land-use increases approximately 110 percent from 1984 to 2002. Most of the increases are associated with medium-to high-density urban development. Places having significant increases in impervious surfaces are in the northwestern and southeastern parts of Las Vegas. Most high-density urban development, however, appears in central Las Vegas. Impervious surface conditions for 2002 measured from Landsat and ASTER satellite data are compared in terms of their accuracy. ?? 2008 American Society for Photogrammetry and Remote Sensing.

  5. GRACE and ICESat Data for Estimation of Ice Sheet Surface Changes in LAS, East Antarctica

    NASA Astrophysics Data System (ADS)

    Xie, H.; Ju, X.; Liu, J.; Gu, Z.; Liu, S.; Tian, Y.; Chen, L.; Shen, Y.; Tong, X.; Sun, B.; Li, R.

    2014-12-01

    Knowledge of mass changes of the Antarctic ice sheet is essential for understanding global climate change, specifically, for sea-level change. This presentation reports the the results of a comparative study on changes of regional ice sheet mass and surface elevation based on observations of GRACE and ICESat satellites over the period of 2004 - 2008 in the Lambert Glacier-Amery Ice Shelf System (LAS), East Antarctica. LAS is an important drainage system in East Antarctica and one of the significant contributors to the mass budget of the Antarctic. We fitted the GRACE monthly solutions to a model that contains a linear trend, an acceleration, annual and semiannual terms, and a 161 days tide aliasing term (S2). We employed the IJ05 R2 GIA model. For ICESat observations, we employed a modified spatial-temporal polynomial model to describe the ice surface topography and an annual elevation change rate (trend), which is solved by using repeat-track points within a moving box along the repeating tracks. Uncertainties of the source data and the estimated trends from both GRACE and ICESat data are given. The mass changes from GRACE and ICESat are compared and the differences are analyzed. A number of key issues in the comparison and mass - volume conversion are discussed. Afterwards, spatial and temporal correlations between the results at the annual change level derived from the two data sets are analyzed. Impact of firn models, GIA models, and comparison with other research results in LAS demonstrated.

  6. The Las Vegas Valley Seismic Response Project: Ground Motions in Las Vegas Valley from Nuclear Explosions at the Nevada Test Site

    SciTech Connect

    Rodgers, A; Tkalcic, H; McCallen, D

    2005-03-18

    Between 2001-2004 the Las Vegas Seismic Response Project has sought to understand the response of Las Vegas Valley (LVV) to seismic excitation. In this study, the author report the findings of this project with an emphasis on ground motions in LVV from nuclear explosions at the Nevada Test Site (NTS). These ground motions are used to understand building structural response and damage as well as human perception. Historical nuclear explosion observations are augmented with earthquake recordings from a temporary deployment of seismometers to improve spatial coverage of LVV. The nuclear explosions were conducted between 1968 and 1989 and were recorded at various sites within Las Vegas. The data from past nuclear tests were used to constrain ground motions in LVV and to gain a predictive capability of ground motions for possible future nuclear tests at NTS. Analysis of ground motion data includes peak ground motions (accelerations and velocities) and amplification of basin sites relative to hard rock sites (site response). Site response was measured with the Standard Spectral Ratios (SSR) technique relative to hard rock reference sites on the periphery of LVV. The site response curves indicate a strong basin amplification of up to a factor of ten at frequencies between 0.5-2 Hz. Amplifications are strongest in the central and northern portions of LVV, where the basin is deeper than 1 km based on the reported basin depths of Langenheim et al (2001a). They found a strong correlation between amplification and basin depth and shallow shear wave velocities. Amplification below 1 Hz is strongly controlled by slowness-averaged shear velocities to depths of 30 and 100 meters. Depth averaged shear velocities to 10 meters has modest control of amplifications between 1-3 Hz. Modeling reveals that low velocity material in the shallow layers (< 200 m) effectively controls amplification. They developed a method to scale nuclear explosion ground motion time series to sites around LVV

  7. Final Report for the Arroyo Las Positas Maintenance Impact Study, Lawrence Livermore National Laboratory

    SciTech Connect

    van Hattem, M; Paterson, L

    2006-01-12

    In 2000, the Lawrence Livermore National Laboratory's (LLNL) Environmental Protection Department, in coordination with Plant Engineering (PE), began dredging sections of the Arroyo Las Positas (ALP) to alleviate concerns about flooding of sensitive facilities within the mainsite of Lawrence Livermore National Laboratory. In order to reduce potential impacts on the federally threatened California red-legged frog (Rana aurora draytonii), LLNL proposed to dredge sections of the ALP in a ''checkerboard pattern'', resulting in a mosaic of open water habitat and vegetated sections (Figure 1). The Arroyo Las Positas Management Plan (Plan) was coordinated with both state and federal agencies including the U.S. Fish and Wildlife Service (USFWS), California Department of Fish and Game (CDF&G), San Francisco Regional Water Quality Control Board (SFRWQCB), and the Army Corp of Engineers (ACOE). Water Discharge Requirements (WDRs) were issued for this project on December 30, 1999 (Order No. 99-086) by the SFRWQCB. Provision 19 of the WDRs outlined a five-year (2000 through 2004) Maintenance Impact Study (MIS) that LLNL began in coordination with dredging work that was conducted as part of the Arroyo Las Positas Management Plan. Provision 20 of these WDRs requires LLNL to submit a final report of the results of the Maintenance Impact Study for this project to the SFRWQCB. The purpose of this report is to present the results of the Maintenance Impact Study for Arroyo Las Positas and meet the requirements of Provision 20. A description of the annual monitoring included in this Maintenance Impact Study is included in the methods section of this report. Initially the Plan called for dredging the entire length of the Arroyo Las Positas (approximately 6,981 linear feet) over a 5-year period to minimize temporal impacts on the California red-legged frog. Dredging occurred in 2000 ({approx}1,300 ft.), 2001 ({approx}800 ft.), and 2002 ({approx}1,200 ft.), which constituted approximately

  8. An Aerial Radiological Survey of Selected Areas of the City of North Las Vegas

    SciTech Connect

    Piotr Wasiolek

    2008-06-01

    As part of the proficiency training for the Radiological Mapping mission of the Aerial Measuring System (AMS), a survey team from the Remote Sensing Laboratory-Nellis (RSL-Nellis) conducted an aerial radiological survey of selected areas of the city of North Las Vegas for the purpose of mapping natural radiation background and locating any man-made radioactive sources. Survey areas were selected in collaboration with the City Manager's office and included four separate areas: (1) Las Vegas Motor Speedway (10.6 square miles); (2) North Las Vegas Downtown Area (9.2 square miles); (3) I-15 Industrial Corridor (7.4 square miles); and (4) Future site of University of Nevada Las Vegas campus (17.4 square miles). The survey was conducted in three phases: Phase 1 on December 11-12, 2007 (Areas 1 and 2), Phase 2 on February 28, 2008 (Area 3), and Phase 3 on March 19, 2008 (Area 4). The total completed survey covered a total of 44.6 square miles. The flight lines (without the turns) over the surveyed areas are presented in Figures 1, 2, 3, and 4. A total of eight 2.5-hour-long flights were performed at an altitude of 150 ft above ground level (AGL) with 300 feet of flight-line spacing. Water line and test line flights were conducted over the Lake Mead and Government Wash areas to ensure quality control of the data. The data were collected by the AMS data acquisition system (REDAR V) using an array of twelve 2-inch x 4-inch x 16-inch sodium iodide (NaI) detectors flown on-board a twin-engine Bell 412 helicopter. Data, in the form of gamma energy spectra, were collected continually (every second) over the course of the survey and were geo-referenced using a differential Global Positioning System. Collection of spectral data allows the system to distinguish between ordinary fluctuations in natural background radiation levels and the signature produced by man-made radioisotopes. Spectral data can also be used to identify specific radioactive isotopes. As a courtesy service, with

  9. Earthquakes in the Classroom, Las Vegas, NV: The Nevada Educational Seismic Network (NESN)

    NASA Astrophysics Data System (ADS)

    Hopkins, J.; Snelson, C. M.; Zaragoza, S. A.; Smith, K.; Depolo, D.

    2002-12-01

    Geophysics is a term guaranteed to strike fear into the heart of the bravest high school science student. Using math to describe the earth can involve complex equations that can only be deciphered by enigmatic computer programs. But high school science students in the Las Vegas Valley have been given a unique opportunity to gather important research information while learning about geophysics, real-time data collection, and Internet communications in a less threatening environment. Three seismograph stations funded by the Department of Energy and the University of Nevada, Las Vegas have been installed in three different high schools in the Clark County School District. These three stations form a triangle in the Las Vegas Valley basin covering areas where the basin depths change significantly. The geophones are buried outside and a cable connects the sensors and GPS receiver to a digitizer on a local PC. The data is transmitted continuously in real-time via Internet communications protocols to the Seismic Explorer Monitoring Network. There it is available to all schools and to researchers who will analyze the data. These short-period geophones will record small local earthquakes and larger more distant events contributing to real-time seismic network operations in southern Nevada. Students at a school site are able to see live real-time data from other school stations as well as from seismograph stations in southern Nevada, the western US, and the world. Mentored by researchers at the University of Nevada, Reno and University of Nevada, Las Vegas, the teachers and students conduct simple waveform analysis to determine earthquake locations and magnitudes and operate the stations in this cooperative research effort. The goal of this partnership between secondary and university educational systems is to create a successful alliance that will benefit the research community as well as the classroom teacher and his/her students. Researchers will use the data collected

  10. Long-term assessment of ultrafine particles on major roadways in Las Vegas, Nevada and Detroit, Michigan

    EPA Science Inventory

    This is a presentation at the National Air Monitoring conference, given at the request of OAQPS partners. The presentation will cover ultrafine particle data collected at three locations - Las Vegas, Detroit, and Research Triangle Park.

  11. 75 FR 60496 - Kern Valley Railroad Company-Termination of Trackage Rights-in Las Animas County, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-30

    ... rights held by BNSF Railway Company (BNSF) to operate over KVR's 2-mile Jansen Yard Segment between milepost 0.0 and milepost 2.0 in Jansen, Las Animas County, Colo. (the line). The line traverses...

  12. A substitution at His-120 in the LasA protease of Pseudomonas aeruginosa blocks enzymatic activity without affecting propeptide processing or extracellular secretion.

    PubMed Central

    Gustin, J K; Kessler, E; Ohman, D E

    1996-01-01

    The LasA protease of Pseudomonas aeruginosa can degrade elastin and is an important contributor to the pathogenesis of this organism. LasA (20 kDa) is a member of the beta-lytic endopeptidase family of extracellular bacterial proteases, and it shows high-level staphylolytic activity. We sequenced the lasA gene from strain FRD1 and overexpressed it in Escherichia coli. The lasA gene encodes a precursor, known as pre-proLasA, of 45,582 Da. Amino-terminal sequence analysis allowed the identification of the signal peptidase cleavage site and revealed that the 31-amino-acid signal peptide was removed in E. coli. The remaining proLasA (42 kDa) did not undergo autoproteolytic processing and showed little staphylolytic activity. However, it was readily processed to a 20-kDa active staphylolytic protease by incubation with trypsin or with the culture filtrate of a P. aeruginosa lasAdelta mutant. Thus, removal of the propeptide (22 kDa) was required to convert proLasA into an active protease. Although LasA protease was critical for staphylolytic activity, other proteases like elastase were found to enhance staphylolysis. Under the control of an inducible trc promoter, lasA was overexpressed in P. aeruginosa and the processing intermediates were examined. Compared with wild-type cells, the overproducing cells accumulated more 42-kDa proLasA species, and the culture supernatants of the overproducing cells showed increased levels of active 20-kDa LasA protease. Small amounts of a 25-kDa extracellular LasA-related protein, which could represent a potential processing intermediate, were also observed. To better understand the structure-function relationships in LasA protease, we tested whether His-120-X-His-122 in the mature portion of LasA plays a role in activity. This motif and surrounding sequences are conserved in the related beta-lytic protease of Achromobacter lyticus. Oligonucleotide-directed mutagenesis was used to change His-120 to Ala-120, thus forming the lasA5 allele

  13. Seismic Data for Evaluation of Ground Motion Hazards in Las Vegas in Support of Test Site Readiness Ground Motion

    SciTech Connect

    Rodgers, A

    2008-01-16

    In this report we describe the data sets used to evaluate ground motion hazards in Las Vegas from nuclear tests at the Nevada Test Site. This analysis is presented in Rodgers et al. (2005, 2006) and includes 13 nuclear explosions recorded at the John Blume and Associates network, the Little Skull Mountain earthquake and a temporary deployment of broadband station in Las Vegas. The data are available in SAC format on CD-ROM as an appendix to this report.

  14. A continuous spectrophotometric assay for Pseudomonas aeruginosa LasA protease (staphylolysin) using a two-stage enzymatic reaction.

    PubMed

    Kessler, Efrat; Safrin, Mary; Blumberg, Shmaryahu; Ohman, Dennis E

    2004-05-15

    Pseudomonas aeruginosa LasA protease is a secreted metalloendopeptidase that can lyse Staphylococcus aureus cells by cleaving the pentaglycine bridges of their peptidoglycan. It can also degrade elastin and stimulate shedding of cell-surface proteoglycans, activities implicated in pathogenesis of P. aeruginosa infections. The activity of LasA protease can be assayed spectrophotometrically by following the reduction in turbidity of S. aureus cell suspensions. This assay, however, does not permit kinetic studies and its reproducibility is poor. Here we describe a two-stage enzymatic reaction for the continuous measurement of LasA protease activity using a defined substrate, succinyl-Gly-Gly-Phe-4-nitroanilide, supplemented with Streptomyces griseus aminopeptidase. Cleavage of the Gly-Phe bond by LasA protease is followed by hydrolysis of the product Phe-4-nitroanilide by the aminopeptidase and the rate of release of the chromophore (4-nitroaniline) is measured spectrophotometrically using a 96-well microplate reader. Activity of nanogram amounts of LasA protease could be determined within a few minutes. Furthermore, this assay permitted the determination of Km and kcat values for LasA protease, which were 0.46 mM and 11.8s(-1), respectively. Pseudomonas elastase was also active in the assay. However, it was less effective than LasA protease and its activity was inhibited by phosphoramidon. The assay is highly sensitive and reproducible, providing a convenient tool for further studies of LasA protease function(s) and mechanism of action. PMID:15113701

  15. A brief hydrologic appraisal of the July 3-4, 1975, flash flood in Las Vegas Valley, Nevada

    USGS Publications Warehouse

    Katzer, T.L.; Glancy, Patrick A.; Harmsen, Lynn

    1976-01-01

    Heavy thunderstorm precipitation on the afternoon of July 3, 1975, between metropolitan Las Vegas and the mountains to the south, west, and north, caused flash flooding in the city area. Total storm precipitation equaled or exceeded 3 inches (76 mm) in some areas. The total storm yield on the area of significant runoff was probably between 20,000 and 25,000 acre-feet (2.5 x 107 m3 and 3.1 x 107 m3) of water. Of this amount, probably less than 3,000 acre-feet (37 x 106 m3) flowed directly to Lake Mead. Peak flows of Tropicana Wash, Flamingo Wash, Las Vegas Creek, and Las Vegas Wash were the highest ever determined. Flooding caused the loss of two lives and inflicted extensive property damage. Total damage was reportedly estimated by the Clark County Flood Control District at $4-5 million. Problems associated with sediment erosion, transportation, and deposition occurred throughout the flooded area. An unknown amount of the material transported during the flood was deposited in Lake Mead near the mouth of Las Vegas Wash. Lateral erosion appeared more prominent than vertical erosion along most major channels, except on Las Vegas Wash at Northshore Road where downcutting threatened the loss of the highway. Sediment deposits were particularly noticeable and troublesome in Flamingo Wash at Caesars Palace parking lot and on the Winterwood Golf Course near the junction of Flamingo Wash and Las Vegas Wash.

  16. An Aerial Radiological Survey of the City of North Las Vegas (Downtown) and the Motor Speedway

    SciTech Connect

    Piotr Wasiolek

    2007-12-01

    As part of the proficiency training for the Radiological Mapping mission of the Aerial Measuring System (AMS), a survey team from the Remote Sensing Laboratory-Nellis (RSL-Nellis) conducted an aerial radiological survey on December 11-12, 2007, with the purpose of mapping natural radiation background and locating any man-made radioactive sources. The survey covered 19.4 square miles (9.2 square miles over the downtown area of the City of North Las Vegas and 10.2 square miles over the Las Vegas Motor Speedway [LVMS]). The flight lines over the surveyed areas are presented in Figures 1 and 2. A total of four 2.5-hour-long flights were performed at an altitude of 150 ft above ground level (AGL) with 300 ft of flight line spacing. Water line and test line flights were conducted over the Lake Mead and Government Wash areas to ensure quality control of the data. The data were collected by the AMS data acquisition system-REDAR V using an array of twelve 2-inch x 4-inch x 16-inch sodium iodide (NaI) detectors flown on-board a twin-engine Bell 412 helicopter. Data in the form of gamma energy spectra were collected continually (every second) over the course of the survey and were geo-referenced using a differential Global Positioning System. Collection of spectral data allows the system to distinguish between ordinary fluctuations in natural background radiation levels and the signature produced by man-made radioisotopes sources. Spectral data can also be used to identify specific radioactive isotopes. As a courtesy service with the approval of the U.S. Department of Energy, National Nuclear Security Administration, Nevada Site Office, RSL-Nellis is providing this summary to the office of the Mayor of City of North Las Vegas and LVMS security along with the gross counts-based exposure rate and man-made counts maps.

  17. Seismic Wave Amplification in Las Vegas: Site Response and Empirical Estimates of Ground Motion

    NASA Astrophysics Data System (ADS)

    Rodgers, A.; McCallen, D.; Tkalcic, H.; Wagoner, J.; Louie, J.; Anderson, J.; Luke, B.; Snelson, C.; Taylor, W.

    2004-12-01

    This presentation will summarize a multidisciplinary effort to understand seismic wave amplification in Las Vegas Valley. The project involves weak motion recording and analysis, geotechnical and seismic refraction field studies, geologic and lithologic interpretation and model building. We will provide a brief overview of the project, then focus on specifics of seismic wave amplification including observations and interpretations. We analyzed recordings of nuclear explosions from the Nevada Test Site (NTS) and regional earthquakes to estimate site response in Las Vegas. An empirical transfer function method was used to transform ground motion time-series at one (reference) station to other stations, using frequency dependent site response curves in the band 0.2-5.0 Hz. The method transforms the time-series to the frequency domain by Fast Fourier transform, multiplies the amplitude spectrum by the site response curve and inverse FFT's back to the time domain. The approach is validated by the ability to predict horizontal component S-wave ground motion measures, such as peak and rms ground velocities and accelerations. We then can provide empirical estimates of ground motion for a wider distribution of sites in Las Vegas. Frequency dependent amplifications (site response) and peak ground motions are strongly correlated with measures of shallow shear-wave (geotechnical) velocities. Details of the geotechnical measurements and models will be presented in a companion presentation. This work was performed under the auspices of the U.S. Department of Energy by University of California Lawrence Livermore National Laboratory under contract No. W-7405-Eng-48.

  18. Roles of Pseudomonas aeruginosa las and rhl Quorum-Sensing Systems in Control of Twitching Motility

    PubMed Central

    Glessner, Alex; Smith, Roger S.; Iglewski, Barbara H.; Robinson, Jayne B.

    1999-01-01

    Pseudomonas aeruginosa is a ubiquitous environmental bacterium and an important human pathogen. The production of several virulence factors by P. aeruginosa is controlled through two quorum-sensing systems, las and rhl. We have obtained evidence that both the las and rhl quorum-sensing systems are also required for type 4 pilus-dependent twitching motility and infection by the pilus-specific phage D3112cts. Mutants which lack the ability to synthesize PAI-1, PAI-2, or both autoinducers were significantly or greatly impaired in twitching motility and in susceptibility to D3112cts. Twitching motility and phage susceptibility in the autoinducer-deficient mutants were partially restored by exposure to exogenous PAI-1 and PAI-2. Both twitching motility and infection by pilus-specific phage are believed to be dependent on the extension and retraction of polar type 4 pili. Western blot analysis of whole-cell lysates and enzyme-linked immunosorbent assays of intact cells were used to measure the amounts of pilin on the cell surfaces of las and rhl mutants relative to that of the wild type. It appears that PAI-2 plays a crucial role in twitching motility and phage infection by affecting the export and assembly of surface type 4 pili. The ability of P. aeruginosa cells to adhere to human bronchial epithelial cells was also found to be dependent on the rhl quorum-sensing system. Microscopic analysis of twitching motility indicated that mutants which were unable to synthesize PAI-1 were defective in the maintenance of cellular monolayers and migrating packs of cells. Thus, PAI-1 appears to have an essential role in maintaining cell-cell spacing and associations required for effective twitching motility. PMID:10049396

  19. An Aerial Radiological Survey of the Las Vegas Strip and Adjacent Areas

    SciTech Connect

    Wasiolek, Piotr

    2009-02-01

    As proficiency training for the Radiological Mapping mission of the Aerial Measuring System (AMS), a survey team from the Remote Sensing Laboratory–Nellis (RSL-Nellis) conducted an aerial radiological survey of the Las Vegas Strip and adjacent areas on December 29, 2008. This survey was one of the bi-annual surveys carried in support of the city of Las Vegas Police Department (LVPD) before significant events on the Las Vegas Strip: e.g., the annual New Year’s Eve and July Fourth celebrations. The AMS operation and appropriate law enforcement agencies selected this area as an appropriate urban location to exercise AMS capability for mapping environmental radiation and searching for man-made radioactive sources. The surveys covered approximately 11 square miles. Each survey required a 2.5-hour-long flight, performed at an altitude of 300 ft above ground level (AGL) at a line spacing of 600 ft. Water line and test line flights are conducted over the Lake Mead and Government Wash areas to determine the non-terrestrial background contributed by aircraft, radon, and cosmic activity, and to determine the altitude-dependent air mass correction. The data were collected by the AMS data acquisition system (REDAR V) using an array of twelve 2" x 4" x 16" sodium iodide (NaI) detectors flown on-board a twin-engine Bell 412 helicopter. Gamma energy spectral data were collected second-by-second over the survey area. This spectral data allows the system to distinguish between natural terrestrial background contributions and man-made radioisotope contributions. Spectral data can also be used to identify specific man-made radioactive isotopes. Data geo-locations were determined with a Real-Time Differential Global Positioning System (RDGPS).

  20. Interferograms showing land subsidence and uplift in Las Vegas Valley, Nevada, 1992-99

    USGS Publications Warehouse

    Pavelko, Michael T.; Hoffmann, Jorn; Damar, Nancy A.

    2006-01-01

    The U.S. Geological Survey, in cooperation with the Nevada Department of Conservation and Natural Resources-Division of Water Resources and the Las Vegas Valley Water District, compiled 44 individual interferograms and 1 stacked interferogram comprising 29 satellite synthetic aperture radar acquisitions of Las Vegas Valley, Nevada, from 1992 to 1999. The interferograms, which depict short-term, seasonal, and long-term trends in land subsidence and uplift, are viewable with an interactive map. The interferograms show that land subsidence and uplift generally occur in localized areas, are responsive to ground-water pumpage and artificial recharge, and, in part, are fault controlled. Information from these interferograms can be used by water and land managers to mitigate land subsidence and associated damage. Land subsidence attributed to ground-water pumpage has been documented in Las Vegas Valley since the 1940s. Damage to roads, buildings, and other engineered structures has been associated with this land subsidence. Land uplift attributed to artificial recharge and reduced pumping has been documented since the 1990s. Measuring these land-surface changes with traditional benchmark and Global Positioning System surveys can be costly and time consuming, and results typically are spatially and temporally sparse. Interferograms are relatively inexpensive and provide temporal and spatial resolutions previously not achievable. The interferograms are viewable with an interactive map. Landsat images from 1993 and 2000 are viewable for frames of reference to locate areas of interest and help determine land use. A stacked interferogram for 1992-99 is viewable to visualize the cumulative vertical displacement for the period represented by the individual interferograms. The interactive map enables users to identify and estimate the magnitude of vertical displacement, visually analyze deformation trends, and view interferograms and Landsat images side by side. The

  1. Perchlorate in water, soil, vegetation, and rodents collected from the Las Vegas Wash, Nevada, USA.

    PubMed

    Smith, Philip N; Yu, Lu; McMurry, Scott T; Anderson, Todd A

    2004-11-01

    Water, soil, vegetation, and rodents were collected from three areas along the Las Vegas Wash, a watershed heavily contaminated with perchlorate. Perchlorate was detected at elevated concentrations in water, soil, and vegetation, but was not frequently detected in rodent liver or kidney tissues. Broadleaf weeds contained the highest concentrations of perchlorate among all plant types examined. Perchlorate in rodent tissues and vegetation was correlated with perchlorate concentrations in soil as expected, however rodent residues were not highly correlated with plant perchlorate concentrations. This indicates that soil may be a greater source, or a more constant source of perchlorate exposure in rodents than vegetation. PMID:15276280

  2. Crystal Structure of the LasA Virulence Factor from Pseudomonas aeruginosa: Substrate Specificity and Mechanism of M23 Metallopeptidases

    SciTech Connect

    Spencer, James; Murphy, Loretta M.; Conners, Rebecca; Sessions, Richard B.; Gamblin, Steven J.

    2010-09-21

    Pseudomonas aeruginosa is an opportunist Gram-negative bacterial pathogen responsible for a wide range of infections in immunocompromized individuals and is a leading cause of mortality in cystic fibrosis patients. A number of secreted virulence factors, including various proteolytic enzymes, contribute to the establishment and maintenance of Pseudomonas infection. One such is LasA, an M23 metallopeptidase related to autolytic glycylglycine endopeptidases such as Staphylococcus aureus lysostaphin and LytM, and to DD-endopeptidases involved in entry of bacteriophage to host bacteria. LasA is implicated in a range of processes related to Pseudomonas virulence, including stimulating ectodomain shedding of the cell surface heparan sulphate proteoglycan syndecan-1 and elastin degradation in connective tissue. Here we present crystal structures of active LasA as a complex with tartrate and in the uncomplexed form. While the overall fold resembles that of the other M23 family members, the LasA active site is less constricted and utilizes a different set of metal ligands. The active site of uncomplexed LasA contains a five-coordinate zinc ion with trigonal bipyramidal geometry and two metal-bound water molecules. Using these structures as a starting point, we propose a model for substrate binding by LasA that explains its activity against a wider range of substrates than those used by related lytic enzymes, and offer a catalytic mechanism for M23 metallopeptidases consistent with available structural and mutagenesis data. Our results highlight how LasA is a structurally distinct member of this endopeptidase family, consistent with its activity against a wider range of substrates and with its multiple roles in Pseudomonas virulence.

  3. Phlebotominae spatial distribution asssociated with a focus of tegumentary leishmaniasis in Las Lomitas, Formosa, Argentina, 2002.

    PubMed

    Salomón, Oscar Daniel; Orellano, Pablo Wenceslao; Lamfri, Mario; Scavuzzo, Marcelo; Dri, Lucía; Farace, María Isabel; Quintana, Darío Ozuna

    2006-05-01

    Las Lomitas, Formosa, Argentina, reported 96 cases of tegumentary leishmaniasis during 2002. The urban transmission was suggested although previous outbreaks were related with floods of the Bermejo river (BR) 50 km from the village. Phlebotomine collections were performed during March 2002 to define the spatial distribution of risk, together with satellite imaginery. The phlebotomine/trap obtained was 1679.5 in the southern BR shore, 1.1 in the periruban-rural environment and 2.3 in the northern Pilcomayo river marshes. Lutzomyia neivai was the prevalent species (91.1%) among the 2393 phlebotomine captured, and it was only found in the BR traps. The other species were L. migonei (7.9%), L. cortelezzii (0.9%), and Brumptomyia guimaraesi (0.1%). The satellite images analysis indicates that the fishing spots at the BR were significantly overflowed during the transmission peak, consistent with fishermen recollections. This spatial restricted flood might concentrate vectors, reservoirs, and humans in high places. Therefore, both the spatial distribution of vectors and the sensor remoting data suggests that in Las Lomitas area the higher transmission risk it is still related with the gallery forest of the BR, despite of the urban residence of the cases. The surveillance and control implications of these results are discussed. PMID:16862326

  4. Influence of composition and temperature on hydrocarbon migration through Morrow fluvial reservoirs, Las Animas Arch, Colorado

    SciTech Connect

    Bolyard, D.W.

    1995-06-01

    Precipitation of wax in pores may impair permeability and prohibit the flow of oil. Crude oil composition and temperature are the most important controlling factors. Oils are chemically complex, may contain up to 45 wax compounds and may vary significantly even in the same pool. High-wax oils are common in the Morrow of eastern Colorado. Narrow fluvial sandstones provide migration paths toward the Las Animas Arch from adjacent basins. Temperatures range from less than 110{degrees}F. on the top of the arch to 180{degrees}F at a structural position only 1,400 feet lower. A range of 30{degrees}F has been observed in individual pools. Wax has precipitated in the 120-140{degrees}F range, creating relative permeability barriers which cut across the sandstones. Wax barriers are impermeable to oil, but may be permeable to gas and water. They account for certain dry holes with high porosity, permeability and oil saturation (and low water saturation) in both core and electrical log analysis. They explain why some oil wells with impaired permeability are adjacent to structurally lower gas wells with good permeability. A network of wax barriers around the Las Animas Arch accounts for approximately 300 feet of variation in the structural position of a line separating oil from gas fields. Since the low temperature bands may be short and discontinuous, wax barriers are more effective in narrow fluvial reservoirs than in blanket reservoirs.

  5. INTRAVAL Phase 2: Modeling testing at the Las Cruces Trench Site

    SciTech Connect

    Hills, R.G.; Wierenga, P.J.; Luis, S.; McLaughlin, D.; Rockhold, M.; Xiang, J.; Scanlon, B.; Wittmeyer, G.

    1994-01-01

    Several field experiments have been performed by scientists from the University of Arizona and New Mexico State University at the Las Cruces Trench Site to provide data tc test deterministic and stochastic models for water flow and solute transport. These experiments were performed in collaboration with INTRAVAL, an international effort toward validation of geosphere models for the transport of radionuclides. During Phase I of INTRAVAL, qualitative comparisons between experimental data and model predictions were made using contour plots of water contents and solute concentrations. Detailed quantitative comparisons were not made. To provide data for more rigorous model testing, a third Las Cruces Trench experiment was designed by scientists from the University of Arizona and New Mexico State University. Modelers from the Center for Nuclear Waste Regulatory Analysis, Massachusetts Institute of Technology, New Mexico State University, Pacific Northwest Laboratory, and the University of Texas provided predictions of water flow and tritium transport to New Mexico State University for analysis. The corresponding models assumed soil characterizations ranging from uniform to deterministically heterogeneous to stochastic. This report presents detailed quantitative comparisons to field data.

  6. Seasonal subsidence and rebound in Las Vegas Valley, Nevada, observed by synthetic aperture radar interferometry

    USGS Publications Warehouse

    Hoffmann, J.; Zebker, H.A.; Galloway, D.L.; Amelung, F.

    2001-01-01

    Analyses of areal variations in the subsidence and rebound occurring over stressed aquifer systems, in conjunction with measurements of the hydraulic head fluctuations causing these displacements, can yield valuable information about the compressibility and storage properties of the aquifer system. Historically, stress-strain relationships have been derived from paired extensometer/piezometer installations, which provide only point source data. Because of the general unavailability of spatially detailed deformation data, areal stress-strain relations and their variability are not commonly considered in constraining conceptual and numerical models of aquifer systems. Interferometric synthetic aperture radar (InSAR) techniques can map ground displacements at a spatial scale of tens of meters over 100 km wide swaths. InSAR has been used previously to characterize larger magnitude, generally permanent aquifer system compaction and land subsidence at yearly and longer timescales, caused by sustained drawdown of ground-water levels that produces intergranular stresses consistently greater than the maximum historical stress. We present InSAR measurements of the typically small-magnitude, generally recoverable deformations of the Las Vegas Valley aquifer system occurring at seasonal timescales. From these we derive estimates of the elastic storage coefficient for the aquifer system at several locations in Las Vegas Valley. These high-resolution measurements offer great potential for future investigations into the mechanics of aquifer systems and the spatial heterogeneity of aquifer system structure and material properties as well as for monitoring ongoing aquifer system compaction and land subsidence.

  7. Ground-water conditions in Las Veags Valley, Clark County, Nevada; part 1 Hydrogeologic Framework

    USGS Publications Warehouse

    Plume, Russell W.

    1989-01-01

    This report describes the lithology, thickness, and extent of valley-fill deposits in Las Vegas Valley, Nev. This information will be used to develop a hydraulic model of the valley's ground-water system. Las Vegas Valley is a structural basin formed by bedrock that ranges in age from Precambrian through Miocene. Gravity data indicate that the deeper parts of the basin are filled with 3,000-5,000 feet of clastic sedimentary deposits that range in age from Miocene through Holocene. These deposits constitute the valley-fill aquifer and yield most of the water pumped in the valley. The upper 1,000 feet of this valley fill consist of coarse-grained deposits (sand and gravel), fine-grained deposits (silt and clay), and heterogeneous deposits that comprise either thinly interbedded coarse- and fine-grained deposits or mixtures of the two. Coarse-grained deposits, in places more than 1,000 feet thick, underlie the south and west sides of the valley and interfinger with fine-grained and heterogeneous deposits toward the center of the valley. Intervals of fairly thin heterogeneous deposits underlie parts of the valley, but they are not laterally persistent. The distribution of coarse-grained and fine-grained deposits in three depth zones of the valley fill (0-200 feet, 200-700 feet, and 700-1,000 feet) suggests that: (1) the Spring Mountains and McCullough Range were the major sources of clastic material for the valley fill; (2) Frenchman Mountain and the Las Vegas Range were emplaced later than the Spring Mountains; (3) the east side of the Spring Mountains, which was originally closer to the center of the valley, has receded westward because of erosion; and (4) shallow, fine-grained deposits (0-200 feet deep) are more susceptible to subsidence than deeper ones. The bedrock basin that underlies Las Vegas Valley consists of a deeply buried part that underlies most of the valley and a shallow bedrock surface on the west side of the valley. The deep part of the basin is

  8. Quaternary Faults and Basin-fill Sediments of the Las Vegas Basin, Southern Nevada

    NASA Astrophysics Data System (ADS)

    Taylor, W. J.; Fossett, E.; Luke, B.; Snelson, C.; Rasmussen, T.; McCallen, D.; Rodgers, A.; Louie, J.

    2003-12-01

    The N-S elongated extensional Las Vegas basin, southern Nevada, contains 100's of meters of Cenozoic basin-fill sediments that are cut by several Quaternary (Q) faults. These faults define or influence the basin geometry. The basin is generally an asymmetrical half graben defined by the W-dipping, Q Frenchman Mountain fault (FMF) along its E side and a series of smaller offset E-dipping faults to the W. The N terminus of the basin is controlled by the Las Vegas Valley shear zone, along which the majority of the offset occurred prior to the Q. Here, we asses the influence of the Q faults on the distribution of the sedimentary units. Well, exposure, seismic reflection and seismic refraction data show that sedimentary units of different grain sizes or seismic velocity dominate different parts of the basin. Sections dominated by coarse clastic deposits occupy a narrow area along the E side of the basin. Coarse clastic sediments are mixed with finer grained sediments in a broader area along the W side of the basin. Based on provenance and alluvial fan distribution, the coarse deposits along the E side of the basin appear to be trapped in close proximity to the W-dipping FMF. The coarse-grained deposits along the opposite, W side of the basin, are sourced from the nearby Spring Mountains. Because of the structural asymmetry of the basin, these sediments traveled farther from their source area than those on the E side. Some of these E-dipping faults influence the depth to Paleozoic bedrock and some faults form small sub-basins filled with finer grained sediments. Along a WNW trend near the center of the basin and near the present-day Las Vegas Wash, a change in the grain size distribution occurs up stratgraphic section: continuous clay layers are less common and coarse-grained deposits are more common. This difference may reflect a change from internal drainage early in the basin history to external drainage through the Las Vegas Wash in the latter history of the basin

  9. MBAS (Methylene Blue Active Substances) and LAS (Linear Alkylbenzene Sulphonates) in Mediterranean coastal aerosols: Sources and transport processes

    NASA Astrophysics Data System (ADS)

    Becagli, S.; Ghedini, C.; Peeters, S.; Rottiers, A.; Traversi, R.; Udisti, R.; Chiari, M.; Jalba, A.; Despiau, S.; Dayan, U.; Temara, A.

    2011-12-01

    Methylene Blue Active Substances (MBAS) and Linear Alkylbenzene Sulphonates (LAS) concentrations, together with organic carbon and ions were measured in atmospheric coastal aerosols in the NW Mediterranean Basin. Previous studies have suggested that the presence of surfactants in coastal aerosols may result in vegetation damage without specifically detecting or quantifying these surfactants. Coastal aerosols were collected at a remote site (Porquerolles Island-Var, France) and at a more anthropised site (San Rossore National Park-Tuscany, Italy). The chemical data were interpreted according to a comprehensive local meteorological analysis aiming to decipher the airborne source and transport processes of these classes of compounds. The LAS concentration (anthropogenic surfactants) was measured in the samples using LC-MS/MS, a specific analytical method. The values were compared with the MBAS concentration, determined by a non-specific analytical method. At Porquerolles, the MBAS concentration (103 ± 93 ng m -3) in the summer samples was significantly higher than in the winter samples. In contrast, LAS concentrations were rarely greater than in the blank filters. At San Rossore, the mean annual MBAS concentration (887 ± 473 ng m -3 in PM10) contributed about 10% to the total atmospheric particulate organic matter. LAS mean concentration in these same aerosol samples was 11.5 ± 10.5 ng m -3. A similar MBAS (529 ± 454 ng m -3) - LAS (7.1 ± 4.1 ng m -3 LAS) ratio of ˜75 was measured in the fine (PM2.5) aerosol fraction. No linear correlation was found between MBAS and LAS concentrations. At San Rossore site the variation of LAS concentrations was studied on a daily basis over a year. The LAS concentrations in the coarse fraction (PM10-2.5) were higher during strong sea storm conditions, characterized by strong air flow coming from the sea sector. These events, occurring with more intensity in winter, promoted the formation of primary marine aerosols containing LAS

  10. The study of ozone variations in the Las Vegas metropolitan area using remote sensing information and ground observations

    USGS Publications Warehouse

    Xian, G.; Crane, M.

    2006-01-01

    Urban development in the Las Vegas Valley, Nevada, has grown rapidly in the past fifty years. Associated with this growth has been a change in landscape from natural cover types to developed urban land mixed with planned vegetation canopy throughout in the metropolitan area. Air quality in the Las Vegas Valley has been affected by increases in anthropogenic emissions and concentrations of carbon monoxide, ozone, and criteria pollutants of particular matter. Ozone concentration in the region is generally influenced by synoptic and mesoscale meteorological conditions, as well as regional transport of pollutants from the western side of Las Vegas. Local influences from ground-level nitrogen oxide emissions and vegetation canopy coverage also affect ozone concentration. Multi-year observational data collected by a network of local air monitoring stations in Clark County, Nevada, indicate that ozone maximums develop in May and June, while minimums exist primarily from November to February. Ozone concentrations are high on the west and northwest sides of the valley. A nighttime ozone reduction in the urban area characterizes the heterogeneous features of spatial distribution for average ozone levels in the Las Vegas urban area. The urban vegetation canopy has a locally positive effect by reducing ozone in urban areas. Decreased ozone levels associated with increased urban development density suggests that the highest ozone concentrations are associated with medium- to low-density urban development in Las Vegas.

  11. The Las Cañadas caldera (Tenerife, Canary Islands): an overlapping collapse caldera generated by magma-chamber migration

    NASA Astrophysics Data System (ADS)

    Marti, J.; Gudmundsson, A.

    2000-12-01

    The Las Cañadas caldera is one of the most important geological structures of Tenerife. Stratigraphic, structural, volcanological, petrological, geochronological, and geophysical data suggest that the Las Cañadas caldera resulted from multiple vertical collapse episodes that occurred during the construction of the Las Cañadas edifice Upper Group. Three long-term (≥200 ka) cycles of phonolitic explosive activity, each culminating with a caldera collapse, have been identified in the Upper Group. During the construction of the Upper Group, the focus of felsic volcanism migrated from west to east. Using the results of field observations, experimental analogue models and numerical studies, we propose that the formation of the overlapping Las Cañadas collapse caldera is related to the migration of the associated magma chamber. Our model implies that each collapse of this overlapping caldera partly, or completely, destroyed the feeding magma chamber. This destruction led to changes in the local stress field that favoured the formation of a new chamber at one side of the previous one, resulting in magma-chamber migration. The proposed model accounts for the formation of the Las Cañadas caldera. In particular, it explains the geometrical relationships, stratigraphy and chronology of the caldera wall deposits. Comparison with other overlapping collapse calderas suggests that our model may apply to other overlapping calderas.

  12. WASP suppresses the growth defect of Saccharomyces cerevisiae las17Delta strain in the presence of WIP.

    PubMed

    Rajmohan, Rajamuthiah; Meng, Lei; Yu, Shangjuan; Thanabalu, Thirumaran

    2006-04-01

    Wiskott-Aldrich syndrome is caused by alterations in the Wiskott-Aldrich syndrome protein (WASP) and several of these mutations affect WASP's interaction with WIP (WASP-interacting protein), suggesting that loss of interaction between WASP and WIP is causal to the disease. Las17p is the yeast homologue of WASP and las17Delta strain is unable to grow at 37 degrees C. We show that Human WASP suppresses the growth defect of Saccharomyces cerevisiae las17Delta strain, only in the presence of WIP. WIP mediates cortical localisation of WASP as well as stabilise WASP in yeast cells. Mutations which affected WASP-WIP interaction abolished WASP's ability to suppress the growth defect of las17Delta strain. We have demonstrated that WASP-WIP is an active complex and WASP's ability to suppress the growth defect of las17Delta strain is dependent on the presence of a functional Arp2/3 activating domain of WASP and also the Verprolin domain (V) of WIP. PMID:16488394

  13. A design for a new catalog manager and associated file management for the Land Analysis System (LAS)

    NASA Technical Reports Server (NTRS)

    Greenhagen, Cheryl

    1986-01-01

    Due to the larger number of different types of files used in an image processing system, a mechanism for file management beyond the bounds of typical operating systems is necessary. The Transportable Applications Executive (TAE) Catalog Manager was written to meet this need. Land Analysis System (LAS) users at the EROS Data Center (EDC) encountered some problems in using the TAE catalog manager, including catalog corruption, networking difficulties, and lack of a reliable tape storage and retrieval capability. These problems, coupled with the complexity of the TAE catalog manager, led to the decision to design a new file management system for LAS, tailored to the needs of the EDC user community. This design effort, which addressed catalog management, label services, associated data management, and enhancements to LAS applications, is described. The new file management design will provide many benefits including improved system integration, increased flexibility, enhanced reliability, enhanced portability, improved performance, and improved maintainability.

  14. Vertical collapse origin of Las Cañadas caldera (Tenerife, Canary Islands) revealed by 3-D magnetotelluric inversion

    NASA Astrophysics Data System (ADS)

    Piña-Varas, P.; Ledo, J.; Queralt, P.; Marcuello, A.; Bellmunt, F.; Ogaya, X.; Pérez, N.; Rodriguez-Losada, J. A.

    2015-03-01

    Tenerife island geology is one of the most complexes of the Canaries archipelago. This complexity is evidenced by the existing controversy regarding the lateral or vertical collapse origin of the Las Cañadas caldera. The resistivity structure of the Las Cañadas caldera has been determined by the 3-D inversion of 188 broadband magnetotelluric data. The resistivity distribution obtained in the final model shows clear evidences of the presence of a vertical structure under the Teide, associated to the buried northern wall of the caldera. Additionally, the characteristics of the main resistivity structure, a ring-shaped low-resistivity body (<10 Ω m) interpreted as a hydrothermal clay alteration cap, would point out the presence of a handwall for the Icod Valley lateral landslide located under the Teide, but not in the southern caldera wall (current wall). All these support the vertical collapse hypothesis to explain the origin of the Las Cañadas caldera.

  15. Sociohydrology of an Arid City: Development of a Coupled Model of Water Management in Las Vegas

    NASA Astrophysics Data System (ADS)

    Garcia, M. E.; Islam, S.; Portney, K. E.

    2014-12-01

    Rapidly growing cities in arid regions present a significant water management challenge. Key to tackling this challenge is understanding how and why some cities transition to more sustainable water management; acknowledging that urban water resources decisions are both responding to and precipitating hydrologic change, this question is best tackled through a sociohydrology approach. While coupling of natural and societal systems is in it's infancy in the field of hydrology, there is a strong tradition of studying coupled systems in the field of Socio-Ecological Systems. We build on Ostrom's Socio-Ecological Systems framework to develop a system dynamics model of water management for the Las Vegas metropolitan area using Vensim. A key objective our proposed modeling framework is to illuminate the dynamic interactions of the sociohydrologic system components and enable testing of various assumptions and strategies. The model of Las Vegas water management consists of five sub-modules: water supply, water demand, finances, public perception and policy making process. The development of the first three modules were based on clearly defined system structure. The public perception sub-module tracks the level public risk perception of a water supply shortage and represents the hypothesis that public risk perception is updated periodically when shortage events are experienced. The policy making process module uses an algorithm capturing the hypothesized decision making process to select policy actions (or in-action) from a set of feasible actions in response to the system states tracked by the model and observable to decision makers. The model was tested and parameterized using mix of quantitative data on water demands, supplies and costs and qualitative data from document analysis and interview data covering 1990 to 2010 period. Given that not only the parameters but also the structure of the public perception and the policy making process sub-systems is contested, a

  16. Aerosol Optical Properties of Smoke from the Las Conchas Wildfire, Los Alamos, NM

    NASA Astrophysics Data System (ADS)

    Gorkowski, K.; Dubey, M. K.; Flowers, B. A.; Aiken, A. C.; Klein, B. Z.; Mazzoleni, C.; Sharma, N.; China`, S.

    2011-12-01

    The Las Conchas wildfire in Northern New Mexico started on June, 26 2011 and spread rapidly, eventually burning an area of 634 km2 (245 mi2). Due to the close proximity to the fire, the Los Alamos National Laboratory (LANL) was shut down and the town evacuated for several days. Immediately after LANL reopened (7/6/2011) the Earth and Environmental Sciences Division (EES-14) attained unique measurements of the smoke by sampling the ambient air. Three Integrated Photoacoustic/Nephelometer Spectrometers (DMT Inc.) were set up to measure aerosol light absorption and scattering coefficients. A University of Northwest Switzerland thermodenuder was used to remove compounds that are volatile at temperatures up to 200C. The aerosol's optical properties were measured before and after denuding the sample at 405nm (blue), 532nm (green), 781nm (red), and for non-denuded particles also at 375nm (ultraviolet). The aerosol size distributions were measured after the denuder with a Laser Aerosol Spectrometer (LAS, TSI Inc.) and black carbon was measured with a Single Particle Soot Photometer (SP2, DMT Inc.). Additionally, ambient measurements of Total Particulate Matter (PM2.5 and PM10) were collected continuously at the LANL air monitoring stations. These measurements are used in conjunction with numerical simulations to determine the bulk optical properties of the aerosol. Aerosols in wildfire smoke are composed of organic and black carbon (soot) particles that are formed during wood combustion and pyrolysis. The optical properties of the smoke particles are complex and lead to large uncertainties in assessing the global climate. During the measurement period, the Las Conchas fire provided very high particle concentrations (up to 200 μg/m3) that were exploited to investigate their optical properties. By heating the particles to temperatures ranging from 75 to 200C in the denuder, volatile organics were removed and the optical properties of the remaining particles were measured

  17. Structural controls on diffuse degassing in the Las Cañadas caldera, Tenerife, Canary Islands

    NASA Astrophysics Data System (ADS)

    Galindo, I.; Soriano, C.; Martí, J.; Pérez, N.

    2003-04-01

    The Las Cañadas caldera is an elliptical depression located in the central part of the Tenerife Island. The active Teide stratovolcano stands in the centre of the depression, which is limited to the south by the caldera wall, up to 500 m high above the caldera floor. Mapping most of the caldera wall at 1:5000 has provided new insights on its stratigraphy, structure, and geological evolution. Three major ENE-WSW normal faults have been mapped on the caldera wall in the area comprised between El Llano de Ucanca and Los Azulejos, where an intense hydrothermal alteration affects the lower stratigraphic levels of the caldera wall. Hydrothermal alteration is rather distinctive in this area, showing bluish to greenish colours. Most of the phonolitic cone sheets and radial dykes of the caldera wall do not show distinctive hydrothermal features, as do show the phonolitic pyroclastic rocks and lavas of the lower parts of the caldera wall. This suggests the main episodes of dyke intrusion in the Las Cañadas caldera postdate hydrothermal alteration. ENE-WSW normal faults involve dyke swarms and rocks of the upper stratigraphic levels of the caldera wall, and show displacements of up to 100 m. Unfortunately the upper possible age of these faults is poorly constrained since no contact relationship has been observed between fault planes and the rocks of the uppermost stratigraphic levels of the caldera wall. The rocks of the caldera wall adjacent to the faults are intensely fractured at the macro and mesoscale. In addition to field mapping, a soil gas survey was carried out at the caldera depression. Soil CO2 efflux and H2 concentration were measured reaching values of 12 gm-2d-1 and 4 ppmV, respectively. Spatial distribution of these species showed that positive anomalies coincide with the surface expression of the three major faults and their adjacent intensely fractured zone. The high CO2 and H2 values and their coincidence with major normal faults suggests that degassing in

  18. Geodetic Constraints on Fault Slip Rates and Seismic Hazard in the Greater Las Vegas Area

    NASA Astrophysics Data System (ADS)

    Hammond, W. C.; Kreemer, C.; Blewitt, G.; Broermann, J.; Bennett, R. A.

    2014-12-01

    We address fundamental questions about how contemporary tectonic deformation of the crust in the southern Great Basin occurs in the region around Las Vegas (LV) Nevada, western Arizona and eastern California. This area lies in the intersection of the eastern Walker Lane Belt, southern Great Basin and western Colorado Plateau (CP), sharing features of transtensional and extensional deformation associated with Pacific/North America relative motion. We use GPS data collected from 48 stations of the MAGNET semi-continuous network and 77 stations from continuous networks including BARGEN and EarthScope Plate Boundary Observatory. MAGNET stations have been observed for a minimum of 7 years, while most continuous stations have longer records. From these data we estimate the velocity of crustal motion for all stations with respect to the stable North America reference frame NA12. To correct for transients from recent large earthquakes including the 1999 Hector Mine and 2010 El Mayor-Cucapah events we use models of co- and post-seismic deformation, subtracting the predicted motions from the time series before estimating interseismic stain rates. We find approximately 2 mm/yr of relative motion distributed over 200 km centered on Las Vegas, with a mean strain accumulation rate of 10 × 10-9 yr-1, with lower rates of predominantly extensional strain to the east and higher rates of predominantly shear deformation to the west. The mean strain rate is lower than that of the western Walker Lane but about twice that of eastern Nevada where e.g., the Wells, NV MW 6.0 earthquake occurred in 2008. From this new velocity field we generated a horizontal tensor strain rate map and a crustal block motion model to portray the transition of active strain from the CP into the Walker Lane. For faults in the Las Vegas Valley, including the Eglington Fault and Frenchman Mountain Fault, the observed velocity gradients and model results are consistent with normal slip rates of 0.2 mm/yr, which

  19. Epitope specificity of murine and human bactericidal antibodies against PorA P1.7,16 induced with experimental meningococcal group B vaccines.

    PubMed

    Rouppe van der Voort, E M; Kuipers, B; Brugghe, H F; van Unen, L M; Timmermans, H A; Hoogerhout, P; Poolman, J T

    1997-03-01

    Synthetic peptides derived from the predicted loops 1 and 4 of meningococcal PorA, sero-subtype P1.7,16, were used to study the epitope specificity of murine and human PorA P1.7,16 bactericidal antibodies. The predicted loops 1 and 4 are surface exposed and carry in their apices the sero-subtype epitopes P1.7 (loop 1) or P1.16 (loop 4), respectively. Peptides were synthesized as mono- and multimeric peptides. Murine monoclonal and polyclonal antibodies were induced with meningococcal whole cell preparations. Polyclonal antibodies were evoked in volunteers after one immunization with 50 micrograms or 100 micrograms protein of a hexavalent meningococcal PorA vesicle vaccine. The induction of PorA antibodies was determined in ELISA using purified PorA P1.7,16. The epitope specificity of anti-PorA antibodies for both murine and human antibodies could be demonstrated by direct peptide ELISA using overlapping multimeric peptides almost spanning the entire loops 1 or 4 of the protein. The capacity of peptides to inhibit the bactericidal activity of murine and human antibodies was investigated using meningococcal strain H44/76 (B:15:P1.7,16) as a target strain. Bactericidal activities could be inhibited with both monomeric and multimeric peptides derived from epitopes P1.7 and P1.16. PMID:9093834

  20. Targeting of Neisserial PorB to the mitochondrial outer membrane: an insight on the evolution of β-barrel protein assembly machines.

    PubMed

    Jiang, Jhih-Hang; Davies, John K; Lithgow, Trevor; Strugnell, Richard A; Gabriel, Kipros

    2011-11-01

    Mitochondria originated from Gram-negative bacteria through endosymbiosis. In modern day mitochondria, the Sorting and Assembly Machinery (SAM) is responsible for eukaryotic β-barrel protein assembly in the mitochondrial outer membrane. The SAM is the functional equivalent of the β-barrel assembly machinery found in the outer membrane of Gram-negative bacteria. In this study we examined the import pathway of a pathogenic bacterial protein, PorB, which is targeted from pathogenic Neisseria to the host mitochondria. We have developed a new method for measurement of PorB assembly into mitochondria that relies on the mobility shift exhibited by bacterial β-barrel proteins once folded and separated under semi-native electrophoretic conditions. We show that PorB is targeted to the outer mitochondrial membrane with a dependence on the intermembrane space shuttling chaperones and the core component of the SAM, Sam50, which is a functional homologue of BamA that is required for PorB assembly in bacteria. The peripheral subunits of the SAM, Sam35 and Sam37, which are essential for eukaryotic β-barrel protein assembly but do not have distinguishable functional homologues in bacteria, are not required for PorB assembly in eukaryotes. This shows that PorB uses an evolutionary conserved 'bacterial like' mechanism to infiltrate the host mitochondrial outer membrane. PMID:22032638

  1. Paleoslope, sea-level and climate controls on Upper Miocene platform evolution, Las Negras area, southeastern Spain

    USGS Publications Warehouse

    Franseen, E.K.; Goldstein, R.H.

    1996-01-01

    Carbonate platforms in the Las Negras area evolved from onlapping ramps to fringing reef complexes later draped by cyclic shallow marine strata. Although sea-level history and paleoclimate had an effect on platform evolution, substrate topography played a dominant role. The strata are divided into five depositional sequences of Tortonian and Messinian age. The model of platform evolution provided by the Las Negras area exposures likely has applications for other Miocene carbonate complexes in the Mediterranean and could apply to other carbonate complexes in the rock record.

  2. Prevalence of ectoparasitic arthropods on wild animals and cattle in the Las Merindades area (Burgos, Spain)

    PubMed Central

    Domínguez-Peñafiel, G.; Giménez-Pardo, C.; Gegúndez, M.I.; Lledó, L.

    2011-01-01

    This paper reports the prevalence of ectoparasitic arthropods in sampled groups of wild (n = 128; 16 species) and domestic (n = 69; 3 species) animals in the Las Merindades area of the Province of Burgos, Spain. The study revealed that wild animals were more infested and with a wider variety of ectoparasites than domestic animals. The parasitic prevalence was 67% for wild animals and 48% for livestock. In this way, 39% of animals were infected by ticks. Ixodes ricinus and Ixodes hexagonus were the most prevalent species whereas Dermacentor reticulatus showed affinity for the fox and wolf. The overall prevalence of parasitisation by fleas was 27%. Ctenophthalmus spp. showed the wider range host in wild animals, while Pulex irritans was the most frequent specie found. The parasitic prevalences by lice (Trichodectes melis, Trichodectes canis and Trichodectes mustelae) and by mite (Neotrombicula spp., Laelaps agilis and Sarcoptes scabiei) were 4% and 12%, respectively. In both cases only wild animals were found parasited. PMID:21894267

  3. Late Neandertals in Southeastern Iberia: Sima de las Palomas del Cabezo Gordo, Murcia, Spain

    PubMed Central

    Walker, Michael J.; Gibert, Josep; López, Mariano V.; Lombardi, A. Vincent; Pérez-Pérez, Alejandro; Zapata, Josefina; Ortega, Jon; Higham, Thomas; Pike, Alistair; Schwenninger, Jean-Luc; Zilhão, João; Trinkaus, Erik

    2008-01-01

    Middle Paleolithic fossil human remains from the Sima de las Palomas in southeastern Iberia (dated to ≤43,000–40,000 calendar years before present) present a suite of derived Neandertal and/or retained ancestral morphological features in the mandibular symphysis, mandibular ramus, dental occlusal morphology, and distal hand phalanx. These traits are combined with variation in the mandibular corpus, discrete dental morphology, tooth root lengths, and anterior dental size that indicate a frequency difference with earlier Iberian and more northern European Neandertals. The Palomas Neandertals therefore confirm the late presence of Neandertals associated with the Iberian persistence of the Middle Paleolithic, but suggest microevolutionary processes and/or population contact with contemporaneous modern humans to the north. PMID:19074275

  4. Neighborhood Reputation and Resident Sentiment in the Wake of the Las Vegas Foreclosure Crisis

    PubMed Central

    Pais, Jeremy; Batson, Christie D.; Monnat, Shannon M.

    2014-01-01

    This study examines how two major components of a neighborhood’s reputation—perceived disorder and collective efficacy—shape individuals’ sentiments toward their neighborhoods during the foreclosure crisis triggered by the Great Recession. Of central interest are whether neighborhood reputations are durable in the face of a crisis (neighborhood resiliency hypothesis) or whether neighborhood reputations wane during times of duress (foreclosure crisis hypothesis). Geo-coded individual-level data from the Las Vegas Metropolitan Area Social Survey merged with data on census tract foreclosure rates are used to address this question. The results provide qualified support for both perspectives. In support of the neighborhood resiliency hypothesis, collective efficacy is positively associated with how residents feel about the quality of their neighborhoods, and this relationship is unaltered by foreclosure rates. In support of the foreclosure crisis hypothesis, foreclosure rates mediate the effects of neighborhood disorder on resident sentiment. The implications of these findings for community resiliency are discussed. PMID:25678735

  5. Polycyclic aromatic hydrocarbons in ambient air particles in the city of Las Palmas de Gran Canaria.

    PubMed

    Vera Castellano, A; López Cancio, J; Santana Alemán, P; Santana Rodríguez, J

    2003-07-01

    Concentration levels, seasonal variation and winter/summer ratios of 11 polycyclic aromatic hydrocarbons (PAHs) in the TSP of Las Palmas de Gran Canaria city were determined. The study area is under the influence of heavy traffic (80000 vehicles/day). Pyr/BaA, Pyr/Flt, B(ghi)P/I(cd)P and B(b+k)F/B(ghi)P ratios were calculated; the values of these two last suggest a strong influence of diesel fuel burning. Levels of TSP and TSP-bound PAHs were also established. The hazard potential of PAHs in terms of carcinogenicity of BaP is acceptable. Potential risk on the basis of TEFs is also studied. PMID:12705945

  6. Las Cumbres Observatory Global Telescope Network: Keeping education in the dark

    NASA Astrophysics Data System (ADS)

    Ross, R.; Roche, P.; Roberts, S.

    2008-06-01

    Las Cumbres Observatory Global Telescope Network (LCOGTN) is a privately-funded, non-profit organisation that is creating a cutting edge science programme paired with an innovative education programme. We are building two networks of telescopes in rings in both the Northern and Southern hemispheres for complete sky coverage, all of which will be equipped with high-quality, science-grade instrumentation. The telescopes will be completely robotic with the ability to be controlled by anyone, from anywhere with a broadband internet connection. Accompanying the observations will be a library of resources and activities including how to plan and carry out an observing session as well as several activities and project ideas to carry out in both formal and informal education settings. The goal is not to produce more astronomers, but to encourage a new understanding of science and technology that people will be able to apply to any field that is studied.

  7. Neandertal postcranial remains from the Sima de las Palomas del Cabezo Gordo, Murcia, southeastern Spain.

    PubMed

    Walker, Michael J; Ortega, Jon; López, Mariano V; Parmová, Klára; Trinkaus, Erik

    2011-04-01

    The Sima de las Palomas, southeastern Spain, has yielded a series of Neandertal postcranial remains, including immature and mature isolated elements and the fragmentary partial skeleton of a young adult (Palomas 92). The remains largely conform to the general late archaic/Neandertal morphological pattern in terms of humeral diaphyseal shape, pectoralis major tuberosity size and pillar thickness, ulnar coronoid process height, manual middle phalangeal epiphyseal breadth, manual distal phalangeal tuberosity shape and breadth, femoral diaphyseal shape, and probably body proportions. Palomas 92 contrasts with the Neandertals in having variably gracile hand remains, a more sellar trapezial metacarpal 1 facet, more anteroposteriorly expanded mid-proximal femoral diaphysis, and less robust pedal proximal phalanges. The Palomas Neandertals contrast with more northern European Neandertals particularly in various reflections of overall body size. PMID:21404228

  8. The Proteus aircraft and NASA Dryden's T-34 in flight over Las Cruces, New Mexico.

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The unique Proteus aircraft served as a test bed for NASA-sponsored flight tests designed to validate collision-avoidance technologies proposed for uninhabited aircraft. The tests, flown over southern New Mexico in March, 2002, used the Proteus as a surrogate uninhabited aerial vehicle (UAV) while three other aircraft flew toward the Proteus from various angles on simulated collision courses. Radio-based 'detect, see and avoid' equipment on the Proteus successfully detected the other aircraft and relayed that information to a remote pilot on the ground at Las Cruces Airport. The pilot then transmitted commands to the Proteus to maneuver it away from the potential collisions. The flight demonstration, sponsored by NASA Dryden Flight Research Center, New Mexico State University, Scaled Composites, the U.S. Navy and Modern Technology Solutions, Inc., were intended to demonstrate that UAVs can be flown safely and compatibly in the same skies as piloted aircraft.

  9. Observed and Simulated Urban Heat Island and Urban Cool Island in Las Vegas

    NASA Astrophysics Data System (ADS)

    Sauceda, Daniel O.

    This research investigates the urban climate of Las Vegas and establishes long-term trends relative to the regional climate in an attempt to identify climate disturbances strictly related to urban growth. An experimental surface station network (DRI-UHI) of low-cost surface temperature (T2m) and relative humidity (RH) sensors were designed to cover under-sampled low-intensity residential urban areas, as well as complement the in-city and surrounding rural areas. In addition to the analysis of the surface station data, high-resolution gridded data products (GDPs) from Daymet (1km) and PRISM (800 m) and results from numerical simulations were used to further characterize the Las Vegas climate trends. The Weather Research and Forecasting (WRF) model was coupled with three different models: the Noah Land Surface Model (LSM) and a single- and multi-layer urban canopy model (UCM) to assess the urban related climate disturbances; as well as the model sensitivity and ability to characterize diurnal variability and rural/urban thermal contrasts. The simulations consisted of 1 km grid size for five, one month-long hindcast simulations during November of 2012: (i) using the Noah LSM without UCM treatment, (ii) same as (i) with a single-layer UCM (UCM1), (iii) same as (i) with a multi-layer UCM (UCM2), (iv) removing the City of Las Vegas (NC) and replacing it with predominant land cover (shrub), and (v) same as (ii) with increasing the albedo of rooftops from 0.20 to 0.65 as a potential adaptation scenario known as "white roofing". T2m long-term trends showed a regional warming of minimum temperatures (Tmin) and negligible trends in maximum temperatures (Tmax ). By isolating the regional temperature trends, an observed urban heat island (UHI) of ~1.63°C was identified as well as a daytime urban cool island (UCI) of ~0.15°C. GDPs agree with temperature trends but tend to underpredict UHI intensity by ~1.05°C. The WRF-UCM showed strong correlations with observed T2m (0

  10. Characterization of stormwater discharges from Las Flores Industrial Park, Rio Grande, Puerto Rico, 1998-99

    USGS Publications Warehouse

    Rodriguez, Jose M.

    2000-01-01

    Stormwater discharges from Las Flores Industrial Park, Rio Grande, Puerto Rico, were characterized from June 1998 to July 1999 by measuring the flow rate at two outfalls, delineating the drainage areas for each outfall, and calculating the volume of the stormwater discharges. Stormwater-discharge samples were collected and analyzed to determine the quality of the discharges. Constituent loads and loads per area were estimated for each drainage area. The studied drainage subareas covered approximately 46 percent of the total area of the Las Flores Industrial Park. Industrial groups represented in the study areas include manufacturers of textile, electronics, paper, fabricated metal, plastic, and chemical products. The concentrations of oil and grease (1 to 6 milligrams per liter), biochemical oxygen demand (4.7 to 16 milligrams per liter), total organic carbon (5.8 to 36 milligrams per liter), total suspended solids (28 to 100 milligrams per liter), and total phosphorous (0.11 to 0.78 milligrams per liter) from all the samples collected were less than the U.S. Environmental Protection Agency stormwater benchmark concentrations. Concentrations of chemical oxygen demand (15.8 to 157 milligrams per liter) and nitrate and nitrite (0.06 to 1.75 milligrams per liter) exceeded benchmark concentrations at one of the studied drainage areas. Total Kjeldahl nitrogen concentrations (1.00 to 3.20 milligrams per liter) exceeded the benchmark concentrations at the two studied drainage areas. Maximum concentrations for oil and grease, biochemical oxygen demand, chemical oxygen demand, total organic carbon, total Kjeldahl nitrogen, nitrate plus nitrite, and total phosphorous were detected in an area where electronics, plastics, and chemical products are currently manufactured. The maximum concentration of total suspended solids was detected at an area where textile, paper, plastic, chemical, and fabricated metal products are manufactured.

  11. Fishery of the Green Jack Caranx caballus (Osteichytes: Carangidae) in Las Perlas Archipelago, Pacific Panama.

    PubMed

    Mair, James M; Cipriani, Roberto; Guzman, Hector M; Usan, David

    2012-09-01

    Green Jacks, Caranx caballus, are distributed along the Eastern Pacific coast. In Panama, C. caballus was heavily fished around Las Perlas Archipelago to sustain local markets until 2007, when the archipelago was declared a marine protected area. This first study in Panama, analyzed a sample of 4 990 individuals from Las Perlas, obtained monthly from June 2005 to June 2006, from landings at the central fish market. Average total length was 36.1 +/- 6.4cm and optimum length 38.9cm. Approximately 68% of fish lengths were within +/-10% of the optimal length but only six (15%) were considered mega-spawners. The von Bertalanffy parameters describe a long-lived and fast growing species, while mortality rates revealed that C. caballus is under high fishing pressure. Standard length at which half of the population is mature was 38.8cm, and the size at which individuals matured massively, 33cm. Only 10-13% of the fish were immature. C. caballus reproduces two to three times per year, with peaks in December, April, and probably September, and recruits to the population at least twice per year. Catch per unit effort (CPUE) was best predicted by minimum annual values of the Multivariate ENSO/LNSO Index (MEI) (R2=0.54). Results show that C. caballus in Pacific Panama is overfished. We recommend the raising of the minimum capture/landing size of this species in order to increase the proportion of mega-spawners in the population and guarantee the sustainability of this resource. PMID:23025097

  12. Stratospheric contribution to surface ozone in the desert Southwest during the 2013 Las Vegas Ozone Study

    NASA Astrophysics Data System (ADS)

    Langford, A. O.; Senff, C. J.; Alvarez, R. J. _II, II; Brioude, J. F.; Cooper, O. R.; Holloway, J. S.; Lin, M.; Marchbanks, R.; Pierce, R. B.; Reddy, P. J.; Sandberg, S.; Weickmann, A. M.; Williams, E. J.; Gustin, M. S.; Iraci, L. T.; Leblanc, T.; Yates, E. L.

    2014-12-01

    The 2013 Las Vegas Ozone Study (LVOS) was designed to investigate the potential impact of stratosphere-troposphere transport (STT) and long-range transport of pollution from Asia on surface O3 concentrations in Clark County, NV. This measurement campaign, which took place in May and June of 2013, was conducted at Angel Peak, NV, a high elevation site about 2.8 km above mean sea level and 45 km west of Las Vegas. The study was organized around the NOAA ESRL truck-based TOPAZ scanning ozone lidar with collocated in situ sampling of O3, CO, and meteorological parameters. These measurements were supported by the NOAA/NESDIS real time modelling system (RAQMS), FLEXPART particle dispersion model, and the NOAA GFDL AM3 model. In this talk, I will describe one of several STT events that occurred during the LVOS campaign. This intrusion, which was profiled by TOPAZ on the night of May 24-25, was also sampled by the NASA Alpha Jet, the Table Mountain ozone lidar, and by an ozonesonde flying above southern California. This event also led to significant ozone increases at surface monitors operated by Clark County, the California Air Resources Board, the U.S. National Park Service, and the Nevada Rural Ozone Initiative (NRVOI), and resulted in exceedances of the 2008 75 ppbv O3 NAAQS both in Clark County and in surrounding areas of Nevada and southern California. The potential implications of this and similar events for air quality compliance in the western U.S. will be discussed.

  13. Unraveling the contributions of hydrogen-bonding interactions to the activity of native and non-native ligands in the quorum-sensing receptor LasR

    PubMed Central

    Gerdt, Joseph P.; McInnis, Christine E.; Schell, Trevor L.; Blackwell, Helen E.

    2014-01-01

    Quorum sensing (QS) via the synthesis and detection of N-acyl L-homoserine lactone (AHL) signals regulates important pathogenic and mutualistic phenotypes in many bacteria. Over the past two decades, the development of non-native molecules that modulate this cell-cell signaling process has become an active area of research. The majority of these compounds were designed for block binding of the native AHL signal to its cognate LuxR-type receptor, and much effort has focused on LasR in the opportunistic pathogen Pseudomonas aeruginosa. Despite a small set of reported LasR structural data, it remains unclear which polar interactions are most important for either (i) activation of the LasR receptor by its native AHL signal, N-(3-oxo)-dodecanoyl L-homoserine lactone (OdDHL), or (ii) activation or inhibition of LasR by related AHL analogs. Herein, we report our investigations into the activity of OdDHL and five synthetic analogs in wild-type LasR and in nine LasR mutants with modifications to key polar residues in their ligand binding sites. Our results allowed us to rank, for the first time, the relative importance of each LasR:OdDHL hydrogen bond for LasR activation and provide strong evidence for the five synthetic ligands binding LasR in a very similar orientation as OdDHL. By delineating the specific molecular interactions that are important for LasR modulation by AHLs, these findings should aid in the design of new synthetic modulators of LasR (and homologous LuxR-type receptors) with improved potencies and selectivities. PMID:25474181

  14. A Catalog of Photometry for Las Campanas Redshift Survey Galaxies on the Sloan Digital Sky Survey System

    SciTech Connect

    Sowards-Emmerd, David; Smith, J. Allyn; McKay, Timothy A.; Sheldon, Erin; Tucker, Douglas L.; Castander, Francisco J.

    2000-06-01

    We present high-quality photometry in the five Sloan Digital Sky Survey filters, u', g', r', i', and z', for 2195 galaxies with spectroscopic redshifts measured by the Las Campanas Redshift Survey. In addition, a polynomial photometric redshift estimator is derived, with an uncertainty of 0.035 out to z = 0.25. (c) 2000 The American Astronomical Society.

  15. A Catalog of Photometry for Las Campanas Redshift Survey Galaxies on the Sloan Digital Sky Survey System

    NASA Astrophysics Data System (ADS)

    Sowards-Emmerd, David; Smith, J. Allyn; McKay, Timothy A.; Sheldon, Erin; Tucker, Douglas L.; Castander, Francisco J.

    2000-06-01

    We present high-quality photometry in the five Sloan Digital Sky Survey filters, u', g', r', i', and z', for 2195 galaxies with spectroscopic redshifts measured by the Las Campanas Redshift Survey. In addition, a polynomial photometric redshift estimator is derived, with an uncertainty of 0.035 out to z=0.25.

  16. Un programa innovador busca ayudar a las personas que cuidan a pacientes con cáncer

    Cancer.gov

    Artículo sobre un programa educativo del City of Hope Cancer Center que ofrece a los profesionales de salud la información y las herramientas necesarias para ayudar a los familiares a saber cómo cuidarse a si mismos y a sus seres queridos con cáncer.

  17. Preliminary information on ambient concentrations measured at the Las Vegas National Near-Road MSAT study site

    EPA Science Inventory

    This paper provides preliminary information on the trends in ambient concentrations observed near a heavily traveled highway in Las Vegas, Nevada. As part of a joint effort by the U.S. Environmental Protection Agency (EPA) and Federal Highway Administration, an air monitoring pro...

  18. Mechanistic analysis of a synthetic inhibitor of the Pseudomonas aeruginosa LasI quorum-sensing signal synthase

    PubMed Central

    Lidor, O.; Al-Quntar, A.; Pesci, E. C.; Steinberg, D.

    2015-01-01

    Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen responsible for many human infections. LasI is an acyl-homoserine lactone synthase that produces a quorum-sensing (QS) signal that positively regulates numerous P. aeruginosa virulence determinants. The inhibition of the LasI protein is therefore an attractive drug target. In this study, a novel in silico to in vitro complementation was applied to screen thiazolidinedione-type compounds for their ability to inhibit biofilm formation at concentrations not affecting bacterial growth. The compound (z)-5-octylidenethiazolidine-2, 4-dione (TZD-C8) was a strong inhibitor of biofilm formation and chosen for further study. Structural exploration of in silico docking predicted that the compound had high affinity for the LasI activity pocket. The TZD-C8 compound was also predicted to create hydrogen bonds with residues Arg30 and Ile107. Site-directed mutagenesis (SDM) of these two sites demonstrated that TZD-C8 inhibition was abolished in the lasI double mutant PAO-R30D, I107S. In addition, in vitro swarming motility and quorum sensing signal production were affected by TZD-C 8, confirming this compound alters the cell to cell signalling circuitry. Overall, this novel inhibitor of P. aeruginosa quorum sensing shows great promise and validates our mechanistic approach to discovering inhibitors of LuxI-type acyl-homoserine lactone synthases. PMID:26593271

  19. Can a Spanish Science Education Journal Become International? The Case of "Enseñanza De Las Ciencias"

    ERIC Educational Resources Information Center

    Espinet, Mariona; Izquierdo, Mercè; Garcia-Pujol, Clara

    2015-01-01

    In this paper we discuss the case of the science education research journal "Enseñanza de las Ciencias" ("EC") around the issue of its internationalization and the consequences this process has had and is still having on the use and preservation of different languages and more specifically the Castilian (Spanish) language. We…

  20. What Happens in Vegas Does "Not" Stay in Vegas: Youth Leadership in the Immigrant Rights Movement in Las Vegas, 2006

    ERIC Educational Resources Information Center

    Revilla, Anita Tijerina

    2012-01-01

    Students calling themselves the Las Vegas Activist Crew shut down the city's famed Strip on May 1, 2006, with an immigrant rights protest that was one of the largest demonstrations in Nevada's history. This research analyzes the ways that students engage in activism to improve their own social conditions and those of their communities. The…

  1. Female Adolescent Subjectivities in Las Vegas: Poststructural Thoughts on the Intersections of Gender, Sexuality, Consumer Logic and Curriculum

    ERIC Educational Resources Information Center

    Dentith, Audrey M.

    2004-01-01

    In this article, data collected from an ethnographic study of adolescent girls growing up in the city of Las Vegas in the US is used to further our understanding of the role of mediated sex and consumer culture and in relationship to emerging adolescent female identities. Girls in this study articulated a clear sense of their abilities to make…

  2. Seasonal and diurnal analysis of NO2 concentrations from a long-duration study conducted in Las Vegas, Nevada

    EPA Science Inventory

    A study, conducted in Las Vegas, NV from mid-December 2008 to mid-December 2009 along an interstate highway, collected continuous and integrated ambient air quality samples for a wide variety of species including NO2 and NOX. Previous near-road studies have been short duration, ...

  3. Ambient air monitoring during the 2011 Las Conchas wildland fire near Los Alamos, U.S.A.

    SciTech Connect

    Green, Andrew A.; Schlemann, Shea A.; Young, Daniel L.

    2012-08-31

    Air monitoring data collected during the Las Conchas fire near the Los Alamos National Laboratory during 2011 are presented. Data included are for selected radionuclides and selected metals found in particulate matter. None of these analytes were seen at levels which exceeded any state or federal standards.

  4. 40 CFR 51.917 - What is the effective date of designation for the Las Vegas, NV, 8-hour ozone nonattainment area?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., AND SUBMITTAL OF IMPLEMENTATION PLANS Provisions for Implementation of 8-hour Ozone National Ambient Air Quality Standard § 51.917 What is the effective date of designation for the Las Vegas, NV, 8-hour... designation for the Las Vegas, NV, 8-hour ozone nonattainment area? 51.917 Section 51.917 Protection...

  5. Análise dos Conceitos Astronômicos Apresentados por Professores de Algumas Escolas Estaduais Brasileiras

    NASA Astrophysics Data System (ADS)

    Voelzke, Marcos Rincon; Gonzaga, Edson Pereira

    2011-12-01

    A razão para o desenvolvimento deste trabalho baseia-se no fato de que muitos professores da Educação Básica (EB) não lidam com conceitos relacionados à astronomia, e quando o fazem eles simplesmente seguem livros didáticos que podem conter erros conceituais. Como é de conhecimento geral a astronomia é um dos conteúdos a serem ensinados na EB fazendo parte dos Parâmetros Curriculares Nacionais e das Propostas Curriculares do Estado de São Paulo, mas é um fato, que vários pesquisadores apontam, a existência de muitos problemas no ensino da astronomia. Com o propósito de minimizar algumas dessas deficiências foi realizado um trabalho de pesquisa com a utilização de questionários pré e pós pesquisa, para tanto foi desenvolvido um Curso de Extensão Universitária para professores da Diretoria de Ensino Regional (DE) que abrange Mauá, Ribeirão Pires e Rio Grande da Serra (no Estado de São Paulo) com os seguintes objetivos: levantar concepções alternativas; subsidiar os professores por meio de palestras, debates e workshops, e verificar o sucesso da aprendizagem após o curso, adotando-se como referência, para a análise dos resultados, os dicionários de Língua Portuguesa (FERREIRA, 2004) e Enciclopédico de Astronomia e Astronáutica (MOURĀO, 1995). Portanto, dezesseis questões foram aplicadas antes e após o curso, assim pode-se verificar após a pesquisa que 100,0% dos professores sabiam os nomes das fases da Lua, 97,0% entenderam que o Sistema Solar é composto por oito planetas, 78,1% foram capazes de explicar como ocorre um eclipse lunar, um eclipse solar e um solstício, 72,7% sabiam como explicar a ocorrência das estações do ano; 64,5% explicaram corretamente a ocorrência do equinócio, 89,7% foram capazes de definir adequadamente o termo cometa; 63,6% definiram asteróide, 54,5% meteoro, 58,1% galáxia, e 42,4% planeta. Os resultados obtidos indicam uma aprendizagem significativa por parte dos participantes.

  6. Human-health pharmaceutical compounds in Lake Mead, Nevada and Arizona, and Las Vegas Wash, Nevada, October 2000-August 2001

    USGS Publications Warehouse

    Boyd, Robert A.; Furlong, Edward T.

    2002-01-01

    The U.S. Geological Survey and the National Park Service conducted a reconnaissance study to investigate the occurrence of selected human-health pharmaceutical compounds in water samples collected from Lake Mead on the Colorado River and Las Vegas Wash, a waterway used to transport treated wastewater from the Las Vegas metropolitan area to Lake Mead. Current research indicates many of these compounds can bioaccumulate and may adversely affect aquatic organisms by disrupting physiological processes, impairing reproductive functions, increasing cancer rates, contributing to the development of antibiotic-resistant strains of bacteria, and acting in undesirable ways when mixed with other substances. These compounds may be present in effluent because a high percentage of prescription and non-prescription drugs used for human-health purposes are excreted from the body as a mixture of parent compounds and degraded metabolite compounds; also, they can be released to the environment when unused products are discarded by way of toilets, sinks, and trash in landfills. Thirteen of 33 targeted compounds were detected in at least one water sample collected between October 2000 and August 2001. All concentrations were less than or equal to 0.20 micrograms per liter. The most frequently detected compounds in samples from Las Vegas Wash were caffeine, carbamazepine (used to treat epilepsy), cotinine (a metabolite of nicotine), and dehydronifedipine (a metabolite of the antianginal Procardia). Less frequently detected compounds in samples collected from Las Vegas Wash were antibiotics (clarithromycin, erythromycin, sulfamethoxazole, and trimethoprim), acetaminophen (an analgesic and anti-inflammatory), cimetidine (used to treat ulcers), codeine (a narcotic and analgesic), diltiazem (an antihypertensive), and 1,7-dimethylxanthine (a metabolite of caffeine). Fewer compounds were detected in samples collected from Lake Mead than from Las Vegas Wash. Caffeine was detected in all samples

  7. Especies del género Tamarix (Tamaricaceae) invadiendo ambientes naturales y seminaturales en Argentina

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Tamarix species (Tamaricaceae) invading natural and seminatural habitats in Argentina. The genus Tamarix includes species behaving as aggressive invaders in the USA, México and Australia. Previous studies report a variable number of species of this genus cultivated in Argentina as ornamentals,wind-b...

  8. Estudio del comportamiento tribologico y de las interacciones de superficie de nuevos nanofluidos ionicos

    NASA Astrophysics Data System (ADS)

    Espinosa Rodriguez, Tulia

    tribocorrosion processes. The formation of a coating layer on magnesium alloys from phosphonate imidazolium ionic liquids by immersion and by chronoamperometry has been described. The new coatings reduce the abrasive wear in the magnesium-aluminium alloy but they are not effective in the magnesium-zinc alloy, which prevent the formation of continuous coatings. Los liquidos ionicos son sales liquidas a temperatura ambiente o bajas temperaturas que presentan excelentes propiedades fisico-quimicas. En el presente trabajo se estudian como lubricantes en problemas tribologicos complejos como la lubricacion de metales contra si mismos, el desarrollo de lubricantes base agua y de nuevas superficies autolubricadas. Cuando no es posible reducir la friccion y desgaste mediante lubricacion, como en las aleaciones de magnesio, los liquidos ionicos se han estudiado como precursores de recubrimientos protectores. Se han determinado las interacciones superficiales y los procesos de corrosion sobre cobre y sobre acero con diferentes liquidos ionicos proticos y aproticos para desarrollar nuevos lubricantes y aditivos. En el contacto cobre/cobre, excepto el liquido ionico protico derivado del oleato, todos los liquidos ionicos estudiados presentan mejor comportamiento tribologico que el lubricante comercial Polialfaolefina 6. En el contacto acero/zafiro, los nuevos liquidos ionicos proticos son buenos lubricantes cuando se utilizan en estado puro, y, como aditivos en agua, generan peliculas adsorbidas sobre la superficie del metal reduciendo la friccion y el desgaste tras la evaporacion del agua. Para evitar el periodo de alta friccion inicial en presencia de agua, se han generado peliculas superficiales de liquido ionico sobre el acero en condiciones estaticas. El mejor comportamiento lubricante tanto en el contacto cobre/cobre como en el contacto acero/zafiro se obtiene para el liquido ionico protico derivado del anion adipato, con dos grupos carboxilicos. Las interacciones de los grupos

  9. Geohydrologic reconnaissance of Lake Mead National Recreation Area; Las Vegas Wash to Virgin River, Nevada

    USGS Publications Warehouse

    Laney, R.L.; Bales, J.T.

    1996-01-01

    This study is the last of a series of eight geohydrologic reconnaissance studies that were done in the Lake Mead National Recreation Area. The studies were done to evaluate the water resources in the recreation area and to identify areas having potential for the development of water supplies that would be adequate for marinas and campgrounds. The study area includes about 250 square miles north of Lake Mead from Las Vegas Wash to the Virgin River (Overton Arm), Nevada. Volcanic rocks, consolidated sedimentary rocks, and unconsolidated to semiconsolidated sedimentary rocks underlie the area. Surface-water sources include the Colorado River, Virgin River, Muddy River, and Las Vegas Wash. Elsewhere in the area, streamflow is meager and extremely variable. Ground water originates from four sources: (1) subsurface flow in local basins, (2) infiltration of water from Lake Mead into permeable rocks near the lake, (3) subsurface flow in valleys of perennial streams, and (4) subsurface flow in consolidated rocks of the Muddy Mountains. The quantity of water from Lake Mead that has saturated rocks adjacent to the lake probably is greater than the quantity of ground water from all the Other sources. Rocks saturated by water from the lake probably extend less than 0.5 mileinland from the lake shore. The quality of virtually all the ground water in the area is not acceptable for drinking purposes. The most favorable areas for obtaining ground water are those underlain by the coarse-grained deposits of the older alluvium and the younger alluvium adjacent to Lake Mead. The least favorable areas are those underlain by the mudstone facies of the Muddy Creek Formation and fine-grained rocks of the Horse Spring Formation. Four areas identified as having potential for ground-water development are (1) near Overton Beach, (2) west of Callville Bay, (3) near Middle Point, and (4) in the lower Moapa Valley. Usable quantities of water probably can be obtained at these sites, but the

  10. Growth and production of Donax striatus (Bivalvia: Donacidae) from Las Balsas beach, Gibara, Cuba.

    PubMed

    Ocaña, Frank A

    2015-09-01

    Clams of the genus Donax are worldwide the dominating group of the invertebrate community on sandy beaches. They are primary consumers that provide a significant abundance and biomass to the ecosystem. In the Caribbean, Donax striatus has an important role for nature and human, nonetheless studies on the population dynamics of this beach clam are scarce and no information exists on secondary production of this species. Growth parameters and secondary production of D. striatus were estimated from February 2008 to November 2009 at Las Balsas beach, Northeastern Cuba, in order to provide basic information for management purposes. In each month 45 samples were taken by means of a PVC corer of 0.025 m2 area and sieved with a 1 mm mesh. Animals were measured and weighted with and without shell. A total of 5 471 specimens were collected during the sampling period. Shell length ranged from 2.7-33.3 mm. Growth parameters estimated from length frequency data were L∞ = 36.1 mm, K= 0.8/yr and t0= 0.2/yr. The growth performance resulted in values of Φ'= 3.02. Life span was 2.4 yrs and mortality rate was 3.07 /yr. In 2008, mean abundance of D. striatus ranged between 17.1 - 770.7 ind./m2. In 2009 the lowest mean abundance was 34.4 and the highest was 892.5 ind./m2. During 2009 biomass and production was more than twice higher in comparison with 2008. Individual production showed highest values in the 24 mm shell size (3.74 g/m2.yr) and 25 mm (0.71 g/m2.yr), considering mass with shell and without shell, respectively. During 2009 abundance of individuals with 15 mm shell length or more increased resulting in higher biomass and production, compared to 2008. Using the conversion factor of wet mass to ash free dry mass (AFDM), annual production ranged between 2.87-6.11 g AFDM/m2.yr, resulting in a turnover rate (P/B) between 5.11 and 3.47 in 2008 and 2009, respectively. The rapid growth and high turnover rate of D. striatus suggest a rapid recovery of the population. These

  11. Las Cumbres Observatory Global Telescope Network: Keeping Education in the Dark

    NASA Astrophysics Data System (ADS)

    Ross, Rachel J.; Geibink, W.; Rosing, W. E.; Brown, T. M.

    2006-12-01

    The Las Cumbres Observatory Global Telescope Network is a privately funded, non-profit organization that is constructing two overlapping networks of robotic telescopes for scientific and educational uses. The educational network will consist of at least thirty 0.4 1.0 meter telescopes that will be longitudinally spaced around the world so that there will always be at least one (more likely several) in the dark at any given time. All will be equipped with high quality CCD imagers, with the 1.0 meters having spectrographs and possible infrared capabilities. All networked telescopes will have identical, completely online interfaces that allow you to control the telescope and use different imaging instruments in either real-time or queued modes. Any registered school or group will have the capability to remotely observe using a telescope that is currently in the dark from the comfort of their classroom or science center, half a world away. Accompanying the robotic observations will be a library of resources and activities that will be usable in the formal classroom setting, informal groups and clubs, and for public outreach in the community for all age-groups and levels of science. Using the LCOGT network as a tool to enjoy real astronomical research will not only create a new awareness for science and technology, but also create connections between science and humanities. We aim to always keep astronomy education in the dark.

  12. Las Cumbres Observatory Global Telescope Network: Keeping Education in the Dark

    NASA Astrophysics Data System (ADS)

    Ross, R. J.; Barton, J. A.; Rosing, W. E.

    2008-06-01

    The Las Cumbres Observatory Global Telescope Network is a privately- funded, non-profit organization that is creating a global network of telescopes ranging in size from 0.4 meter to 2 meters for educational and scientific uses. All will be equipped with high quality CCD imagers with the larger ones with spectrographs. An online interface will be used for observing both in real time and in a queue. Any registered school or group will have the capability to remotely observe using a telescope that is currently in the dark from the comfort of their classroom or science center, half a world away. Accompanying the online telescope-control interface will be a library of resources and activities that will be available in the formal classroom setting, informal groups and clubs, and for public outreach in the community for all age groups and levels of science. Using the LCOGT network as a tool to enjoy real astronomical research will not only create a new awareness and excitement towards science and technology, it will also make visible connections between science and humanities.

  13. Integrated geophysical methods for studying the karst system of Gruta de las Maravillas (Aracena, Southwest Spain)

    NASA Astrophysics Data System (ADS)

    Martínez-Moreno, F. J.; Galindo-Zaldívar, J.; Pedrera, A.; Teixido, T.; Ruano, P.; Peña, J. A.; González-Castillo, L.; Ruiz-Constán, A.; López-Chicano, M.; Martín-Rosales, W.

    2014-08-01

    In this study we contrast the results of different geophysical methods in order to describe the karst system surrounding of the Gruta de las Maravillas cave (Aracena, Spain). A comprehensive study of the geophysical responses of the known cavity was carried out, after which several sections were studied to detect the karst architecture and cave continuity. To ensure precision, the inner 3D-topography of the cave was determined by classical geodetic techniques and a digital terrain model was performed with differential GPS. The microgravity method was used to obtain the residual gravity map of the entire study zone, whose minima could be related to caves. Then, the negative gravity anomalies were analyzed to plan several lines for implementing further geophysical methods: magnetic profiles (MP), electrical resistivity tomography (ERT), induced polarization (IP), 2D seismic prospection (refraction tomography and reflection sections) and ground penetrating radar (GPR). The resulting models for each line explored were integrated with detailed geological maps to establish the unknown continuity of the caves. Finally, we discuss the suitability of each geophysical technique for cave detection in marble with sulfur host rock and propose the best procedures to constrain their geometries.

  14. Generalized Slope Detection and Ranging turbulence profiling at Las Campanas Observatory

    NASA Astrophysics Data System (ADS)

    Goodwin, Michael; Jenkins, Charles; Lambert, Andrew

    2016-09-01

    We present two models of the optical turbulence profile (model-OTP) for Las Campanas Observatory (LCO) based on measurements conducted during 2007 and 2008 using the Generalized Slope Detection and Ranging (SLODAR) method. The model-OTPs can be used as input into simulations to assess the performance of adaptive optics for the Giant Magellan Telescope. Of particular interest is the strength of the ground-layer turbulence for ground-layer adaptive optics. A total of two 1-week observing data was collected using a purpose-built instrument where observations of a bright double star are imaged by 24 × 24 Shack-Hartmann taken with the LCO 100-inch du Pont telescope. The analysis of the data yielded model-OTP consisting of a handful of statistically prominent thin layers that are statistically separated into the ground layer (below 0.5 km) and the free atmosphere for good (25 per cent), typical (50 per cent) and bad (25 per cent) observing conditions. We demonstrate that using the novel technique of Generalized SLODAR we were able to achieve three times the nominal height resolution of SLODAR and uncover important structural details in the ground layer.

  15. Morphological and physical characteristics of the Virgo Cluster - First results from the Las Campanas photographic survey

    NASA Technical Reports Server (NTRS)

    Sandage, A.; Binggeli, B.; Tammann, G. A.

    1985-01-01

    Preliminary results are presented of a photographic survey of the Virgo cluster to the faintest convenient limit of the Las Campanas du Pont 2.5 m reflector, performed in order to study the complexity of both the surface and velocity distributions within the central 6 degree radius region. The survey is described and the resulting Catalog is discussed, and the frequency of galaxy types found and listed in the Catalog is described. The physical properties of the dwarfs are summarized, and luminosity functions are given separately for each morphological type. The progressive change of (MBT) faintward along the morphological sequence from Sc I through Sm and Im types is shown, leading to a calibration of the de Vaucouleurs Lambda luminosity index and a determination of its intrinsic dispersion. The preliminary results on the distribution of galaxies of all types in the two principal subclustering regions found are summarized, and the velocity distributions over the face of the 6 degree core are discussed for the various galaxy types.

  16. Reference materials and intercomparison samples available from the Environmental Monitoring Systems Laboratory - Las Vegas

    SciTech Connect

    Kantor, E.J.; Laska, P.R.

    1985-06-01

    Reference materials and intercomparison samples may be obtained by laboratories involved in the analysis of environmental samples containing radioactivity, pesticides, toxic inorganic species, or toxic organic species. These reference materials and intercomparison samples are available from the US Environmental Protection Agency's Quality Assurance Division located at the Environmental Monitoring Systems Laboratory in Las Vegas (EMSL-LV). These materials are useful for incorporation into a laboratory's quality control program for the evaluation of the precision and accuracy of analytical work. Media used for radiation reference materials are pitchblende, Monazite ore, uranium mill tailings, Mancos shale, fly ash, and water spiked with radionuclides. Radioactivity intercomparison samples consist of water, milk, air, urine, and a simulated diet slurry spiked with radionuclides. Media available for toxic organic reference materials are sludge, shale oil, and rag oil, and for intercomparison samples are soil and water. Characterized fly ash, foundry sludge, and river sediment serve as reference materials for toxic inorganics, while spiked soil and water serve as intercomparison samples. Finally, spiked adipose tissue, blood plasma, urine, and water comprise the pesticide intercomparison samples, and, after the disclosure of the true pesticide compositions and concentrations of these samples, the laboratory can use the samples as reference materials. The reference materials are generally available continuously, but the intercomparison samples are distributed on a scheduled basis and in some cases only to certain laboratories. 9 tables.

  17. Mapping benthic faunal communities in the shallow and deep sediments of Las Perlas Archipelago, Pacific Panama.

    PubMed

    Mair, James M; Cunningham, Sarah L; Sibaja-Cordero, Jeffrey A; Guzman, Hector M; Arroyo, Maria Fernanda; Merino, Daisi; Vargas, Rita

    2009-08-01

    Las Perlas Archipelago (LPA) is located off the Pacific Coast of Panama and was designated as a marine protected area (MPA) in 2007. This baseline study of the shallow and deeper sedimentary habitats of the islands partly informed the MPA designation. Ninety-two grab stations and twenty trawl stations were sampled. Sediment grab sample results were interpolated to produce a map that showed the area to be dominated by mud (1246 km2, 40%) and sand/shell sediments (780 km2, 25%). A total of 201 taxa were recorded and over 5800 individual specimens were processed, revealing that the sediments hold varying community compositions, with annelids being the dominant group (73%) followed by crustaceans (14%). Relationships were evident between community, feeding guilds, and sediment types, which give an indication of communities that can be expected in similar sediments in other areas of the Tropical Eastern Pacific. A study of this scale and level of detail is rare for this biogeographic region and provides a valuable, comprehensive appreciation of the LPA's benthos. PMID:19081116

  18. Las Cumbres Observatory Global Telescope Network: Keeping Education in the Dark

    NASA Astrophysics Data System (ADS)

    Ross, R.

    2010-08-01

    Las Cumbres Observatory Global Telescope Network is building a network of telescopes ranging in size from 0.4-m to 2.0-m for scientific and educational uses. Most of the educational time will be on the 0.4-m network, of which there will be about twenty. Observations will be able to take place in either real-time or queued modes. The educational arm of LCOGT will be primarily through our new website (http://www.lcogt.net) where there will be how-to guides, research projects with our astronomers, activities, and more including an online community through forums and groups. Registered users will also be able to add additional resources, comment on and rate existing pages, collaborate in world-wide research projects, and much more. LCOGT education will be a user-driven community, with everyone working together to create a rich website of resources and information. Although the telescopes are not yet available, there is a vast archive of data that is available to the public and combined with all the projects that can be imagined (and many more that can't), there are countless learning opportunities for in and out of the classroom.

  19. Metallic species in atmospheric particulate matter in Las Palmas de Gran Canaria.

    PubMed

    Cancio, J López; Castellano, A Vera; Hernández, M Chaar; Bethencourt, R García; Ortega, E Macías

    2008-12-30

    In this work, we quantified the total, water-soluble and insoluble fractions of 12 metallic species (Na, Ca, K, Mg, Fe, Zn, Cr, Ni, Cu, Cd, Pb and Mn) present in total suspended particulates (TSP) in an urban area with heavy traffic (about 80 000 vehicles/day) of Las Palmas de Gran Canaria (Canary Islands). Experimental measurements were made from July to December 2003 on a total of 42 samples (7 per month). Particulate matter (TSP) was collected in fiber filters and high volume samplers. PM10 levels were estimated assuming the PM10 fraction is about 70% of all TSP. Total fractions was determined gravimetrically. Water-soluble fraction was extracted by sonication. Concentrations of metallic elements were analyzed by flame atomic absorption spectrophotometer. Temporal changes in the concentrations of the target elements were examined and a multivariate approach used to identify the primary sources for each species. Mean value for TSP is 71.92microg/m3. The water-soluble fraction consisted mainly of Na, Ca, Mg, and K. The insoluble fraction contained higher concentrations of all elements than the soluble except Na. In the water-soluble fraction, Na, K, Ca and Mg were found to come mainly from natural sources; Cr, Pb, Cd, Ni, Zn and Cu from anthropogenic sources. PMID:18440133

  20. Episodic Impacts from California Wildfires Identified in Las Vegas Near-Road Air Quality Monitoring.

    PubMed

    Kimbrough, Sue; Hays, Michael; Preston, Bill; Vallero, Daniel A; Hagler, Gayle S W

    2016-01-01

    Air pollutant concentrations near major highways are usually attributed to a combination of nearby traffic emissions and regional background, and generally presumed to be additive in nature. During a near-road measurement study conducted in Las Vegas, NV, the effects of distant wildfires on regional air quality were indicated over a several day period in the summer of 2009. Area-wide elevated particulate levoglucosan (maximum of 0.83 μg/m(3)) and roadside measurements of ultraviolet light-absorbing particulate matter (UVPM) in comparison to black carbon (Delta-C) were apparent over the three-day period. Back-trajectory modeling and satellite images supported the measurement results and indicated the transport of air pollutants from wildfires burning in southern California. Separating roadside measurements under apparent biomass burning event (Delta-C > 1000 ng m(-3)) and nonevent (Delta-C < 1000 ng m(-3)) periods, and constraining to specific days of week, wind speed range, wind direction from the road and traffic volume range, roadside carbon monoxide, black carbon, total particle number count (20-200 nm), and accumulation mode particle number count (100-200 nm) increased by 65%, 146%, 58%, and 366%, respectively, when biomass smoke was indicated. Meanwhile, ultrafine particles (20-100 nm) decreased by 35%. This episode indicates that the presence of aged wildfire smoke may interact with freshly emitted ultrafine particles, resulting in a decrease of particles in the ultrafine mode. PMID:26618236

  1. Data requirements of GREAT-ER: modelling and validation using LAS in four UK catchments.

    PubMed

    Price, Oliver R; Munday, Dawn K; Whelan, Mick J; Holt, Martin S; Fox, Katharine K; Morris, Gerard; Young, Andrew R

    2009-10-01

    Higher-tier environmental risk assessments on "down-the-drain" chemicals in river networks can be conducted using models such as GREAT-ER (Geography-referenced Regional Exposure Assessment Tool for European Rivers). It is important these models are evaluated and their sensitivities to input variables understood. This study had two primary objectives: evaluate GREAT-ER model performance, comparing simulated modelled predictions for LAS (linear alkylbenzene sulphonate) with measured concentrations, for four rivers in the UK, and investigate model sensitivity to input variables. We demonstrate that the GREAT-ER model is very sensitive to variability in river discharges. However it is insensitive to the form of distributions used to describe chemical usage and removal rate in sewage treatment plants (STPs). It is concluded that more effort should be directed towards improving empirical estimates of effluent load and reducing uncertainty associated with usage and removal rates in STPs. Simulations could be improved by incorporating the effect of river depth on dissipation rates. PMID:19524340

  2. Indicator pathogens, organic matter and LAS detergent removal from wastewater by constructed subsurface wetlands

    PubMed Central

    2014-01-01

    Background Constructed wetland is one of the natural methods of municipal and industrial wastewater treatments with low initial costs for construction and operation as well as easy maintenance. The main objective of this study is to determine the values of indicator bacteria removal, organic matter, TSS, ammonia and nitrate affecting the wetland removal efficiency. Results The average concentration of E. coli and total coliform in the input is 1.127 × 1014 and 4.41 × 1014 MPN/100 mL that reached 5.03 × 1012 and 1.13 × 1014 MPN/100 mL by reducing 95.5% and 74.4% in wetland 2. Fecal streptococcus reached from the average 5.88 × 1014 in raw wastewater to 9.69 × 1012 in the output of wetland 2. Wetland 2 could reduce 1.5 logarithmic units of E. coli. The removal efficiency of TSS for the wetlands is 68.87%, 71.4%, 57.3%, and 66% respectively. Conclusions The overall results show that wetlands in which herbs were planted had a high removal efficiency about the indicator pathogens, organic matter, LAS detergent in comparison to a control wetland (without canes) and could improve physicochemical parameters (DO, ammonia, nitrate, electrical conductivity, and pH) of wastewater. PMID:24581277

  3. Killing of preimplantation mouse embryos by main ingredients of cleansers AS and LAS.

    PubMed

    Nomura, T; Hata, S; Shibata, K; Kusafuka, T

    1987-01-01

    When main ingredients of cleansers, alcohol sulfate (AS) and linear alkylbenzene sulfonate (LAS), were applied to the dorsal skin of pregnant JCL:ICR mice during preimplantation period (days 0-2), significant numbers of embryos collected from the oviducts and uteri on day 3 showed severe deformity or remained at the morula stage. Most of abnormal embryos were fragmented or remained at the 1-8 cell stages, and they were either dead or dying. Even when these abnormal embryos were cultivated in the detergent-free medium, they were not recovered, while most growth-retarded embryos (morula) could grow and hatch with one or two days lag by the further in vitro cultivation. Similar results were observed with commercially obtained kitchen detergent and hair shampoo, although such embryocidal effects were not detected with natural soap and distilled water. Fertilized eggs may be specifically sensitive to synthetic detergents. Very low doses of X-rays also induced significant yields of abnormal embryos. Major difference between X-rays and detergents was that X-ray-induced abnormality appeared at the morula or blastocyst stage, while detergent-induced one did at the earlier stages. PMID:3796668

  4. Posible culto al sol en los grabados rupestres de Las Hurdes (Cáceres).

    NASA Astrophysics Data System (ADS)

    Sevillano, C.

    The author presents a set of rock engravings located in the region of Las Hurdes (Cäceres) a mountainous region to the west of the Central System of the Iberian Peninsula, which present some characteristics different from the other rock engravings known in the Península. In first place the total lack of a narrative character must be underlined, implying that the idea is transmitted through symbols. Essentially the set is formed by geometric scenes, mainly cycles associated with pictures of steps and standing stones. There do exist several schematic motives of weapons and feet as well. On one of the rocks there exists a Roman inscription. The study centers on the circular motives and their associations with other geometric motives, which suggest a possible solar cult, especially in view of the steps which can define the image of a cart, which could be identified with the image of the solar cart. Similarly, on other rock there appear a series of five-spiked stars associated in one case to weapons and in another with foot prints, which provide evidence for a solar cult. In any case, the symbolic character of the figures represented seems to imply the abstraction of a cult, with a magic religious character, in which the idea of the star cult presides the rock symbolism. From the study of the arms represented and because of the Roman inscription one could assign to the set of engravings a chronology which could go from the megalithic to the time of romanization.

  5. Understanding Ground Motion in Las Vegas: Insights from Data Analysis and Two-Dimensional Modeling

    SciTech Connect

    Rodgers, A; Tkalcic, H; McCallen, D

    2004-02-05

    Seismic ground motions are amplified in low velocity sedimentary basins relative to adjacent sites on high velocity hard rock. We used historical recordings of NTS nuclear explosions and earthquake recordings in Las Vegas Valley to quantify frequency-dependent basin amplification using Standard Spectral Ratios. We show that amplifications, referred to as site response, can reach a factor of 10 in the frequency band 0.4-2.0 Hz. Band-averaged site response between 0.4-2.0 Hz is strongly correlated with basin depth. However, it is also well known that site response is related to shallow shear-wave velocity structure. We simulated low frequency (f<1Hz) ground motion and site response with two-dimensional elastic finite difference simulations. We demonstrate that physically plausible models of the shallow subsurface, including low velocity sedimentary structure, can predict relative amplification as well as some of the complexity in the observed waveforms. This study demonstrates that site response can be modeled without invoking complex and computationally expensive three-dimensional structural models.

  6. Immunogenicity and reactogenicity in UK infants of a novel meningococcal vesicle vaccine containing multiple class 1 (PorA) outer membrane proteins.

    PubMed

    Cartwright, K; Morris, R; Rümke, H; Fox, A; Borrow, R; Begg, N; Richmond, P; Poolman, J

    1999-06-01

    The development of effective vaccines against serogroup B meningococci is of great public health importance. We assessed a novel genetically engineered vaccine containing six meningococcal class 1 (PorA) outer membrane proteins representing 80% of prevalent strains in the UK. 103 infants were given the meningococcal vaccine at ages 2, 3 and 4 months with routine infant immunisations, with a fourth dose at 12-18 months. The vaccine was well tolerated. Three doses evoked good immune responses to two of six meningococcal strains expressing PorA proteins contained in the vaccine. Following a fourth dose, larger bactericidal responses to all six strains were observed, suggesting that the initial course had primed memory lymphocytes and revaccination stimulated a booster response. This hexavalent PorA meningococcal vaccine was safe and evoked encouraging immune responses in infants. Vaccines of this type warrant further development and evaluation. PMID:10418910

  7. Crystallization and preliminary X-ray analysis of the C-terminal fragment of PorM, a subunit of the Porphyromonas gingivalis type IX secretion system.

    PubMed

    Stathopulos, Julien; Cambillau, Christian; Cascales, Eric; Roussel, Alain; Leone, Philippe

    2015-01-01

    PorM is a membrane protein involved in the assembly of the type IX secretion system (T9SS) from Porphyromonas gingivalis, a major bacterial pathogen responsible for periodontal disease in humans. The periplasmic domain of PorM was overexpressed in Escherichia coli and purified. A fragment of the purified protein was obtained by limited proteolysis. Crystals of this fragment belonged to the tetragonal space group P4(3)2(1)2. Native and MAD data sets were recorded to 2.85 and 3.1 Å resolution, respectively, using synchrotron radiation. PMID:25615973

  8. Enzymatic depilation of animal hide: identification of elastase (LasB) from Pseudomonas aeruginosa MCM B-327 as a depilating protease.

    PubMed

    Pandeeti, Emmanuel Vijay Paul; Pitchika, Gopi Krishna; Jotshi, Jyotsna; Nilegaonkar, Smita S; Kanekar, Pradnya P; Siddavattam, Dayananda

    2011-01-01

    Conventional leather processing involving depilation of animal hide by lime and sulphide treatment generates considerable amounts of chemical waste causing severe environmental pollution. Enzymatic depilation is an environmentally friendly process and has been considered to be a viable alternative to the chemical depilation process. We isolated an extracellular protease from Pseudomonas aeruginosa strain MCM B-327 with high depilation activity using buffalo hide as a substrate. This 33 kDa protease generated a peptide mass fingerprint and de novo sequence that matched perfectly with LasB (elastase), of Pseudomonas aeruginosa. In support of this data a lasB mutant of MCM B-327 strain lacked depilatory activity and failed to produce LasB. LasB heterologously over-produced and purified from Escherichia coli also exhibited high depilating activity. Moreover, reintroduction of the lasB gene to the P. aeruginosa lasB mutant via a knock-in strategy also successfully restored depilation activity thus confirming the role of LasB as the depilating enzyme. PMID:21347249

  9. Enzymatic Depilation of Animal Hide: Identification of Elastase (LasB) from Pseudomonas aeruginosa MCM B-327 as a Depilating Protease

    PubMed Central

    Pandeeti, Emmanuel Vijay Paul; Pitchika, Gopi Krishna; Jotshi, Jyotsna; Nilegaonkar, Smita S.; Kanekar, Pradnya P.; Siddavattam, Dayananda

    2011-01-01

    Conventional leather processing involving depilation of animal hide by lime and sulphide treatment generates considerable amounts of chemical waste causing severe environmental pollution. Enzymatic depilation is an environmentally friendly process and has been considered to be a viable alternative to the chemical depilation process. We isolated an extracellular protease from Pseudomonas aeruginosa strain MCM B-327 with high depilation activity using buffalo hide as a substrate. This 33 kDa protease generated a peptide mass fingerprint and de novo sequence that matched perfectly with LasB (elastase), of Pseudomonas aeruginosa. In support of this data a lasB mutant of MCM B-327 strain lacked depilatory activity and failed to produce LasB. LasB heterologously over-produced and purified from Escherichia coli also exhibited high depilating activity. Moreover, reintroduction of the lasB gene to the P. aeruginosa lasB mutant via a knock-in strategy also successfully restored depilation activity thus confirming the role of LasB as the depilating enzyme. PMID:21347249

  10. Variations in alluvial style of Tertiary units in response to tectonism, Las Monas area, middle Magdalena valley, Colombia

    SciTech Connect

    Jordan, D.W.; Siemers, C.T.

    1989-03-01

    Detailed sedimentologic and petrographic analyses of Tertiary alluvial sandstone outcrops within and east of producing oil fields in the Las Monas area in Colombia, South America, indicate that depositional style changed from fluvial-deltaic to braided streams atop alluvial fans to high-sinuosity meandering streams in response to uplifts in the surrounding areas. Diverse paleocurrent trends in the Tertiary formations in the perimeter area demonstrate that streams flowed northeast and northwest. Streams in the oil field had easterly and southerly components. Source areas contributing sediment were different and reflected uplifts to the west and south of the Las Monas area. Petrographic composition of sandstones that have easterly and southerly paleocurrent trends in the field area contain more feldspar and less polycrystalline strained quartz than sandstones having a northerly trend in the perimeter area. Sandstones in the field area represent an unroofing of a western granitic terrain, possibly in the ancestral Central Cordillera.

  11. Documentation of potential for surface faulting related to ground-water withdrawal in Las Vegas Valley, Nevada

    USGS Publications Warehouse

    Holzer, Thomas L.

    1978-01-01

    Leveling data collected in Las Vegas Valley are compatible with the interpretation that ongoing land-surface displacements related to ground-water withdrawal may be precursory to fault offset of the land surface. Zones of potential faulting intersect regions of intense urban development. The degree of risk and the potential economic consequences from possible surface faulting cannot be assessed adequately without additional data and analysis of the relation between surface faulting and ground-water withdrawal.

  12. SOURCE AND PATHWAY DETERMINATION FOR BERYLLIUM FOUND IN BECHTEL NEVADA NORTH LAS VEGAS FACILITIES

    SciTech Connect

    BECHTEL NEVADA

    2004-07-01

    In response to the report ''Investigation of Beryllium Exposure Cases Discovered at the North Las Vegas Facility of the National Nuclear Security Administration'', published by the U.S. Department of Energy (DOE), National Nuclear Security Administration (NNSA) in August 2003, Bechtel Nevada (BN) President and General Manager Dr. F. A. Tarantino appointed the Beryllium Investigation & Assessment Team (BIAT) to identify both the source and pathway for the beryllium found in the North Las Vegas (NLV) B-Complex. From September 8 to December 18, 2003, the BIAT investigated the pathway for beryllium and determined that a number of locations existed at the Nevada Test Site (NTS) which could have contained sufficient quantities of beryllium to result in contamination if transported. Operations performed in the B-1 Building as a result of characterization activities at the Engine Maintenance, Assembly, and Disassembly (EMAD); Reactor Maintenance, Assembly, and Disassembly (RMAD); Test Cells A and C; and the Central Support Facility in Area 25 had the greatest opportunity for transport of beryllium. Investigative monitoring and sampling was performed at these sites with subsequent transport of sample materials, equipment, and personnel from the NTS to the B-1 Building. The timeline established by the BIAT for potential transport of the beryllium contamination into the B-1 Building was from September 1997 through November 2002. Based on results of recently completed swipe sampling, no evidence of transport of beryllium from test areas has been confirmed. Results less than the DOE beryllium action level of 0.2 ???g/100 cm2 were noted for work support facilities located in Area 25. All of the identified sites in Area 25 worked within the B-1 tenant's residency timeline have been remediated. Legacy contaminants have either been disposed of or capped with clean borrow material. As such, no current opportunity exists for release or spread of beryllium contamination. Historical

  13. Tritium contamination at EG&G/EM in North Las Vegas, Nevada

    SciTech Connect

    Sowell, C.V.; Arent, L.J.

    1996-06-01

    The tritium contamination discovered at the EG&G Energy Measurements (EG&G/EM) facility in North Las Vegas, Nevada, on 20 April 1995, could have been averted by good health physics practices and/or adequate management oversight. Scandium tritide (ScT{sub 3}) targets were installed for use in sealed tube neutron generators at EG&G/EM. In addition, EG&G/EM was also storing zirconium tritide (ZrT{sub 3}) and titanium tritide (TiT{sub 3}) foils. Since the targets were classified as sealed sources, the appropriate administrative and engineering control measures such as relocating targets/sources, air monitoring, bioassay, waste stream management, labeling/posting and training were not implemented. In all there were six unreported incidents of tritium contamination from March 1994 to July 1995. Swipe surveys revealed areas exceeding the action level of 10,000 dpm/100 cm{sup 2} by up to three orders of magnitude. After reclassifying the targets as unsealed sources, a bioassay program was instituted, and the results were higher than expected for three employees. The doses assigned to the three individuals working in the contaminated area were 35, 58, and 61 mrem committed effective dose equivalent. Though the doses were low, the decontamination costs were in excess of $350,000.00. An investigation, was initiated by the U.S. Department of Energy Nevada Operations Office to analyze the events that led to the tritium contamination and recommend actions to prevent recurrence. Event and causal factor charting, Project Evaluation Tree (PET) analysis techniques, and root cause analysis, were used to evaluate management systems, causal sequences, and systems factors contributing to the tritium release.

  14. Las Cumbres Observatory Global Telescope Network: Keeping Education in the Dark

    NASA Astrophysics Data System (ADS)

    Ross, Rachel J.

    2007-12-01

    Las Cumbres Observatory Global Telescope Network is a non-profit organization that is building a completely robotic network of telescopes for education (24 x 0.4m, clusters of 4) and science (18 x 1.0m, clusters of 3 and 2 x 2.0 meters) which will be longitudinally spaced so there will always be at least one cluster in the dark. The network will be completely accessible online with observations being completed in either real-time or queued-based modes. The network will also have the ability to complete very long observations of all kinds of variable objects and include a rapid response system will allow the telescopes to quickly slew to unexpected phenomena and provide around-the-clock monitoring. Students will be able to do research projects using and collecting data from both the long observations (e.g. extrasolar planet follow-up, variable star light curves, etc.) and the quick response (e.g. supernovae, GRBs, etc.), as well as use their own ideas to create personalized projects. Also available online will be a huge archive of data and the ability to use online software to process it. A large library of activities and resources will be available for all age groups and levels of science. LCOGTN will work cooperatively with international organizations to bring a vast amount of knowledge and experience together to create a world class program. Through these collaborations, pilots have already been started in a few European countries, as well as trial programs involving schools partnered between the USA and UK. LCOGTN's education network will provide an avenue for educators and learners to use cutting edge technology to do real science. All you need is a broadband internet connection, computer, and lots of enthusiasm and imagination.

  15. Geology of Volcan Las Navajas, a pleistocene trachyte/peralkaline rhyolite volcanic center in Nayarit, Mexico

    SciTech Connect

    Hegre, J.A.; Nelson, S.A.

    1985-01-01

    Volcan Las Navajas, located in the northwestern portion of the Mexican Volcanic Belt has produced a sequence of volcanic rocks with compositions in marked contrast to the predominantly calc-alkaline volcanoes which predominate in this part of Mexico. The oldest exposed lavas consist of trachytes with 63% SiO/sub 2/, 6% FeO*, and 500 ppm Zr along with comenditic rhyolites with 68% SiO/sub 2/, 5% FeO*, 800 ppm Zr, and an agpaitic index of 1.0. These lavas were followed by the eruption of a comenditic ash-flow tuff and the formation of a caldera 2.7 km in diameter. This caldera was subsequently filled by eruptions of pantelleritic rhyolite obsidian lava flows with 72% SiO/sub 2/, 8% FeO*, 1100 ppm Zr, and an agpaitic index of 1.5 to 1.9. A second caldera was then formed which is offset to the south of the main eruptive vents for previous eruptions. This younger caldera has a diameter of about 4.8 km and its southern walls have been covered by calc-alkaline andesitic lavas erupted from nearby Sanganguey volcano. Volcanoclastic sediments in the floor of the younger caldera have been tilted and faulted in a manner suggestive of late stage resurgence. Subsequent eruptions within the caldera, however, have been restricted to calc-alkaline andesites. Tectonically, the area in which this volcano occurs appears to have been undergoing a crustal rifting event since the Pliocene. The occurrence of these peralkaline rocks lends further support to such a hypothesis.

  16. More confirmed damped Lyman-Alpha systems from the Las Campanas/Palomar survey

    NASA Technical Reports Server (NTRS)

    Lu, Limin; Wolfe, Arthur M.

    1994-01-01

    We present moderate-resolution spectra of six high-redshift quasars which contain nine candidate damped Lyman alpha absorption systems identified in the Las Campanas/Palomar survey of Lanzetta et al. (ApJS, 77, 1 (1991)). Eight of the nine candidate damped Lyman alpha absorption systems are confirmed (one tentative), including seven with N(H I) greater than or equal to 2 x 10(exp 20) /sq cm. The remaining one turns out to be due to blending of many narrow absorption lines. Accurate absorption redshifts, H I column densities, and metal-line equivalent widths are provided for these systems in order to facilitate future studies of detailed physical condition and chemical abundances. We briefly discuss the 18 other metal-line systems identified along these sight lines. The z(sub abs) = 2.6527 system toward Q 2231-00 is interesting in that it shows strong O VI (lambda) (lambda) 1031, 1037 absorption. The O VI ion is one of the best diagnostics of hot gas, and high resolution studies of the O VI absorption is likely to yield important clues regarding the ionization mechanism of the metal-line systems. Another system, at z(sub abs) = 2.3771 toward Q 2239-38, shows relatively strong Zn II and Cr II absorption, clearly indicating that it belongs to the same class absorbers as the damped Lyman systems. We have not obtained metal abundances for this system because the H(sub I) column density is not available. We also find a Lyman limit absorption system at z(sub abs)= 3.5090 toward Q 2239-38 which does not show obvious metal absorption lines. More sensitive observations are required to check on this interesting possibility.

  17. More confirmed damped Lyman-Alpha systems from the Las Campanas/Palomar survey

    NASA Astrophysics Data System (ADS)

    Lu, Limin; Wolfe, Arthur M.

    1994-07-01

    We present moderate-resolution spectra of six high-redshift quasars which contain nine candidate damped Lyman alpha absorption systems identified in the Las Campanas/Palomar survey of Lanzetta et al. (ApJS, 77, 1 (1991)). Eight of the nine candidate damped Lyman alpha absorption systems are confirmed (one tentative), including seven with N(H I) greater than or equal to 2 x 1020 /sq cm. The remaining one turns out to be due to blending of many narrow absorption lines. Accurate absorption redshifts, H I column densities, and metal-line equivalent widths are provided for these systems in order to facilitate future studies of detailed physical condition and chemical abundances. We briefly discuss the 18 other metal-line systems identified along these sight lines. The zabs = 2.6527 system toward Q 2231-00 is interesting in that it shows strong O VI (lambda) (lambda) 1031, 1037 absorption. The O VI ion is one of the best diagnostics of hot gas, and high resolution studies of the O VI absorption is likely to yield important clues regarding the ionization mechanism of the metal-line systems. Another system, at zabs = 2.3771 toward Q 2239-38, shows relatively strong Zn II and Cr II absorption, clearly indicating that it belongs to the same class absorbers as the damped Lyman systems. We have not obtained metal abundances for this system because the HI column density is not available. We also find a Lyman limit absorption system at zabs= 3.5090 toward Q 2239-38 which does not show obvious metal absorption lines. More sensitive observations are required to check on this interesting possibility.

  18. Flow and transport at the Las Cruces trench site: Experiment IIb

    SciTech Connect

    Vinson, J.; Hills, R.G.; Wierenga, P.J.; Young, M.H.

    1997-07-01

    The US Nuclear Regulatory Commission (NRC) has been directed by Congress in the Low Level Waste Policy Act of 1980 to develop regulatory guidance and assist the individual states and compacts in siting and assessing future low level radioactive waste (LLW) disposal facilities. Three water flow and solute transport experiments were performed as part of a comprehensive field trench study near Las Cruces, New Mexico to test deterministic and stochastic models of vadose zone flow and transport. This report presents partial results from the third experiment (experiment IIb). Experiments IIa and b were conducted on the North side of the trench, on a plot 1.22 m wide by 12 m long, perpendicular to the trench. The area was drip irrigated during two time periods with water containing a variety of tracers. The advance of the water front during the two irrigation episodes was measured with tensiometers and neutron probes. Solute front positions were determined from soil solution sampling through suction samplers and from disturbed sampling. The results from experiment IIb show predominantly downward water movement through the layered unsaturated soil, as evidenced from neutron probe data and gravimetric sampling. Tritium plumes were only half as deep and half as wide as the water plumes at 310 days after the beginning of experiment IIb. Chromium, applied as Cr(VI), moved a readily as, and similar to tritium, but there was a loss of mass due to reduction of Cr(VI) to Cr(III). Chloride and nitrate, initially present at high concentrations in the soil solution, were displaced by the low concentration irrigation water, resulting in chloride and nitrate concentration distributions that looked like negative images of the tritium distributions. The extensive data presented should serve well as a data base for model testing.

  19. Surface and Airborne Arsenic Concentrations in a Recreational Site near Las Vegas, Nevada, USA

    PubMed Central

    Goossens, Dirk

    2015-01-01

    Elevated concentrations of arsenic, up to 7058 μg g-1 in topsoil and bedrock, and more than 0.03 μg m-3 in air on a 2-week basis, were measured in the Nellis Dunes Recreation Area (NDRA), a very popular off-road area near Las Vegas, Nevada, USA. The elevated arsenic concentrations in the topsoil and bedrock are correlated to outcrops of yellow sandstone belonging to the Muddy Creek Formation (≈ 10 to 4 Ma) and to faults crossing the area. Mineralized fluids moved to the surface through the faults and deposited the arsenic. A technique was developed to calculate airborne arsenic concentrations from the arsenic content in the topsoil. The technique was tested by comparing calculated with measured concentrations at 34 locations in the NDRA, for 3 periods of 2 weeks each. We then applied it to calculate airborne arsenic concentrations for more than 500 locations all over the NDRA. The highest airborne arsenic concentrations occur over sand dunes and other zones with a surficial layer of aeolian sand. Ironically these areas show the lowest levels of arsenic in the topsoil. However, they are highly susceptible to wind erosion and emit very large amounts of sand and dust during episodes of strong winds, thereby also emitting much arsenic. Elsewhere in the NDRA, in areas not or only very slightly affected by wind erosion, airborne arsenic levels equal the background level for airborne arsenic in the USA, approximately 0.0004 μg m-3. The results of this study are important because the NDRA is visited by more than 300,000 people annually. PMID:25897667

  20. Site Response in Las Vegas Valley, Nevada from NTS Explosions and Earthquake Data

    NASA Astrophysics Data System (ADS)

    Rodgers, Arthur; Tkalcic, Hrvoje; McCallen, David; Larsen, Shawn; Snelson, Catherine

    2006-01-01

    We report site response in Las Vegas Valley (LVV) from historical recordings of Nevada Test Site (NTS) nuclear explosions and earthquake recordings from permanent and temporary seismic stations. Our data set significantly improves the spatial coverage of LVV over previous studies, especially in the northern, deeper parts of the basin. Site response at stations in LVV was measured for frequencies in the range 0.2 5.0 Hz using Standard Spectral Ratios (SSR) and Horizontal-Vertical Spectral Ratios (HVR). For the SSR measurements we used a reference site (approximately NEHRP B ``rock'' classification) located on Frenchman Mountain outside the basin. Site response at sedimentary sites is variable in LVV with average amplifications approaching a factor of 10 at some frequencies. We observed peaks in the site response curves at frequencies clustered near 0.6, 1.2 and 2.0 Hz, with some sites showing additional lower amplitude peaks at higher frequencies. The spatial pattern of site response is strongly correlated with the reported depth to basement for frequencies between 0.2 and 3.0 Hz, although the frequency of peak amplification does not show a similar correlation. For a few sites where we have geotechnical shear velocities, the amplification shows a correlation with the average upper 30-meter shear velocities, V 30. We performed two-dimensional finite difference simulations and reproduced the observed peak site amplifications at 0.6 and 1.2 Hz with a low velocity near-surface layer with shear velocities 600 750 m/s and a thickness of 100 200 m. These modeling results indicate that the amplitude and frequencies of site response peaks in LVV are strongly controlled by shallow velocity structure.

  1. The Las Cumbres Observatory (LCOGT) Network for NEO and Solar System Science

    NASA Astrophysics Data System (ADS)

    Lister, Tim; Greenstreet, Sarah; Gomez, Edward; Christensen, Eric J.; Larson, Stephen M.

    2016-01-01

    Las Cumbres Observatory Global Telescope Network (LCOGT) has deployed a homogeneous telescope network of nine 1-meter telescopes to four locations in the northern and southern hemispheres, with a planned network size of twelve 1-meter telescopes at 6 locations. This 1-meter network is in addition to the two 2-meter Faulkes Telescopes that have been operating since 2005. This network is very versatile and is designed to respond rapidly to target of opportunity events and also to perform long term monitoring of slowly changing astronomical phenomena. The global coverage of the network and the apertures of telescope available make LCOGT ideal for follow-up and characterization of Solar System objects e.g. Near-Earth Objects (NEOs), comets, asteroids and Kuiper Belt Objects and also for the discovery of new objects.LCOGT has completed the first phase of the deployment with the installation and commissioning of the nine 1-meter telescopes at McDonald Observatory (Texas), Cerro Tololo (Chile), SAAO (South Africa) and Siding Spring Observatory (Australia). The telescope network has been fully operational since 2014 May, and observations are being executed remotely and robotically. Future expansion to sites in the Canary Islands and Tibet are planned for 2016-2017.I will describe the Solar System science research that is being carried out using the LCOGT Network with highlights from the LCOGT NEO Follow-up Network, long-term monitoring of the Rosetta spacecraft target comet 67P and comet C/2013 A1 (Siding Spring) and work on Kuiper Belt Object occultation targets, including Pluto.

  2. Agricultural PM 10 emissions from cotton field disking in Las Cruces, NM

    NASA Astrophysics Data System (ADS)

    Kasumba, John; Holmén, Britt A.; Hiscox, April; Wang, Junming; Miller, David

    2011-03-01

    Various studies have shown a relationship between elevated levels of inhalable particulate matter (PM) and agricultural practices, especially in the vicinity of agricultural fields. Airborne particle concentrations and meteorological variables were measured during nine agricultural field events on a cotton field in Las Cruces, NM in March 2008. A variety of real-time and integrated PM 10 and total suspended particles (TSP) samplers were used during sampling. The field events were designed to measure particle concentrations at different heights, near (4 m) and far (20-100 m) from a disking tractor. Particle concentrations decreased with increasing distance from the ground for near-source disking events, whereas particle concentrations were almost independent of height for background events. Near-source disking event particle concentrations were 4-7 times higher than those for far-source disking and background events. Near-source disking events had PM 10 emission factors ranging from 78 to 239 mg m -2, while those for far-source disking events ranged from 8 to 89 mg m -2. PM 10 plume heights for near-source disking events were between 4 and 5.7 m, whereas those for far-source disking events were between 12 and 15 m. Meteorological variables were found to influence emission factors, with wind speed showing a nonlinear relationship with emission factors. No clear relationship was found between soil moisture content and emission factors probably because the range of soil moisture was small. Impactor data indicated 10-40% of the total mass of agricultural PM collected was less than 1 μm in diameter for the clay loam soil type. Vertical PM 10 concentration profiles showed maxima at sampling heights between 1 and 2 m above the ground.

  3. The Las Cumbres Observatory (LCOGT) Network for NEO and Solar System Science

    NASA Astrophysics Data System (ADS)

    Lister, Tim; Greenstreet, Sarah; Gomez, Edward; Christensen, Eric; Larson, Stephen

    2015-11-01

    Las Cumbres Observatory Global Telescope Network (LCOGT) has deployed a homogeneous telescope network of nine 1-meter telescopes to four locations in the northern and southern hemispheres, with a planned network size of twelve 1-meter telescopes at 6 locations. This 1-meter network is in addition to the two 2-meter Faulkes Telescopes that have been operating since 2005. This network is very versatile and is designed to respond rapidly to target of opportunity events and also to perform long term monitoring of slowly changing astronomical phenomena. The global coverage of the network and the apertures of telescope available make LCOGT ideal for follow-up and characterization of Solar System objects e.g. Near-Earth Objects (NEOs), comets, asteroids and Kuiper Belt Objects and also for the discovery of new objects.LCOGT has completed the first phase of the deployment with the installation and commissioning of the nine 1-meter telescopes at McDonald Observatory (Texas), Cerro Tololo (Chile), SAAO (South Africa) and Siding Spring Observatory (Australia). The telescope network has been fully operational since 2014 May, and observations are being executed remotely and robotically. Future expansion to sites in the Canary Islands and Tibet are planned for 2016-2017.I will describe the Solar System science research that is being carried out using the LCOGT Network with highlights from the LCOGT NEO Follow-up Network, long-term monitoring of the Rosetta spacecraft target comet 67P and comet C/2013 A1 (Siding Spring) and work on Kuiper Belt Object occultation targets, including Pluto.

  4. Petrology, geochemistry and mineralization of the Las Águilas and Virorco mafic-ultramafic bodies, San Luis Province, Argentina

    NASA Astrophysics Data System (ADS)

    Ferracutti, Gabriela; Bjerg, Ernesto; Mogessie, Aberra

    2013-04-01

    The layered mafic-ultramafic rocks in the Sierras de San Luis, Argentina (Las Águilas, Las Higueras and Virorco), constitute a 3-5-km-wide belt that extends over 100 km from NE to SW. They carry a sulphide mineralization consisting of pyrrhotite, pentlandite and chalcopyrite, in veins and as disseminated to massive ore. Disseminated spinels are frequently associated with the sulphide minerals as well as platinum group minerals. A strong correlation between S, Ni, Co, Cu, Cr, Pt and Pd indicates the presence of one to three levels of mineralization within the ultramafic units. The maximum concentration of these elements coincides with the units containing platinum group minerals (PGM) and spinel group minerals. This clear relationship constitutes a good prospecting guide in the search for layers with high-grade ore, probably associated with deeper stratigraphic levels where ultramafic rocks are dominant. The bulk rock chemistry and concentrations of metals and platinum group elements as well as textural evidence suggest that the parental magma was mafic with tholeiitic affinities and MgO rich. The Las Águilas layered mafic-ultramafic body and the remaining bodies in the area bear similar characteristics to well-known stratified complexes developed in extensional tectonic regimes, as it is the case of Jinchuan (China), Kabanga (Tanzania) and Fiambala (Argentina).

  5. LasI/R and RhlI/R Quorum Sensing in a Strain of Pseudomonas aeruginosa Beneficial to Plants▿

    PubMed Central

    Steindler, Laura; Bertani, Iris; De Sordi, Luisa; Schwager, Stephan; Eberl, Leo; Venturi, Vittorio

    2009-01-01

    Pseudomonas aeruginosa possesses three quorum-sensing (QS) systems which are key in the expression of a large number of genes, including many virulence factors. Most studies of QS in P. aeruginosa have been performed in clinical isolates and have therefore focused on its role in pathogenicity. P. aeruginosa, however, is regarded as a ubiquitous organism capable of colonizing many different environments and also of establishing beneficial associations with plants. In this study we examined the role of the two N-acyl homoserine lactone systems known as RhlI/R and LasI/R in the environmental rice rhizosphere isolate P. aeruginosa PUPa3. Both the Rhl and Las systems are involved in the regulation of plant growth-promoting traits. The environmental P. aeruginosa PUPa3 is pathogenic in two nonmammalian infection models, and only the double las rhl mutants are attenuated for virulence. In fact it was established that the two QS systems are not hierarchically organized and that they are both important for the colonization of the rice rhizosphere. This is an in-depth genetic and molecular study of QS in an environmental P. aeruginosa strain and highlights several differences with QS regulation in the clinical isolate PAO1. PMID:19525275

  6. Aerosol Light Absorption and Scattering in Mexico City: Comparison With Las Vegas, NV, and Los Angeles, CA.

    NASA Astrophysics Data System (ADS)

    Paredes-Miranda, G.; Arnott, W. P.; Gaffney, J. S.; Marley, N. A.; Campbell, D.; Fujita, E.

    2007-12-01

    Aerosol light scattering and absorption measurements were deployed in and near Mexico City in March 2006 as part of the Megacity Impacts on Regional and Global Environments (MIRAGE). The primary site in Mexico City was an urban site at Instituto Mexicano del Petroleo (Mexican Oil Institute, denoted by IMP). Similar campaigns were held in Las Vegas, NV in January-February, 2003; and Los Angeles, CA at numerous sites during all seasons from 2003 through 2007. The IMP site gave in-situ characterization of the Mexico City plume under favorable wind conditions. The photoacoustic instrument (PAS) used at IMP operates at 532 nm, and conveniently allowed for characterization of gaseous absorption at this wavelength as well. Light scattering measurements are accomplished within the PAS by the reciprocal nephelometery method. In Mexico City the aerosol absorption coefficient typically varies between 20 and 180 Mm-1 during the course of the day and significant diurnal variation of the aerosol single scattering albedo was observed probably as a consequence of secondary aerosol formation. We will present the diurnal variation of the scattering and absorption as well as the single scattering albedo and fraction of absorption due to gases at the IMP site and compare with Las Vegas diurnal variation. Mexico City 'breaths' more during the course of the day than Las Vegas, Nevada in part because the latitude of Mexico City resulted in more direct solar radiation. Further insight on the meteorological connections and population dynamics will be discussed.

  7. Analysis of the real estate market in Las Vegas: Bubble, seasonal patterns, and prediction of the CSW indices

    NASA Astrophysics Data System (ADS)

    Zhou, Wei-Xing; Sornette, Didier

    2008-01-01

    We analyze 27 house price indices of Las Vegas from June 1983 to March 2005, corresponding to 27 different zip codes. These analyses confirm the existence of a real estate bubble, defined as a price acceleration faster than exponential, which is found, however, to be confined to a rather limited time interval in the recent past from approximately 2003 to mid-2004 and has progressively transformed into a more normal growth rate comparable to pre-bubble levels in 2005. There has been no bubble till 2002 except for a medium-sized surge in 1990. In addition, we have identified a strong yearly periodicity which provides a good potential for fine-tuned prediction from month to month. A monthly monitoring using a model that we have developed could confirm, by testing the intra-year structure, if indeed the market has returned to “normal” or if more turbulence is expected ahead. We predict the evolution of the indices one year ahead, which is validated with new data up to September 2006. The present analysis demonstrates the existence of very significant variations at the local scale, in the sense that the bubble in Las Vegas seems to have preceded the more global USA bubble and has ended approximately two years earlier (mid-2004 for Las Vegas compared with mid-2006 for the whole of the USA).

  8. The U.S. Department of Energy Office of Indian Energy Policy and Programs Las Vegas, Nevada, Roundtable Summary

    SciTech Connect

    2011-03-16

    LAS VEGAS EXECUTIVE SUMMARY The Las Vegas, Nevada DOE Tribal Roundtable convened on March 16th, at the Las Vegas Hilton. The meeting was hosted by the Department of Energy (DOE) Office of Indian Policy and Programs (DOE Office of Indian Energy) and facilitated by JR Bluehouse, Program Manager, Udall Foundation’s U.S. Institute for Environmental Conflict Resolution (U.S. Institute). Mr. Bluehouse was assisted by Tamara, Underwood, Program Assistant, U.S. Institute.  Tribal leaders and representatives from multiple tribal governments and communities attended the roundtable. Tracey LeBeau, newly appointed Director of the Office of Indian Energy attended.    LaMont Jackson from DOE’s Office of Electricity attended. Also attending from the administration and federal agencies were Kim Teehee, Senior Policy Advisor for Native American Affairs, The White House; Charlie Galbraith, Associate Director of the Office of Public Engagement and Deputy Associate Director of the Office of Intergovernmental Affairs, The White House; Jodi Gillette, Deputy Assistant Secretary for Policy and Economic Development, the Bureau of Indian Affairs.

  9. Mapa de Vulnerabilidad en Honduras

    NASA Astrophysics Data System (ADS)

    Sánchez, A. A.

    2013-05-01

    Dado que Honduras geográficamente se encuentra en una zona que esta expuesta a diferentes fenómenos sísmicos y climatológicos. Investigamos cuales son las zonas mas propensas a desastres naturales, la vulnerabilidad y el factor de resiliencia de la población de acuerdo a diferentes parámetros de estudio.

  10. Adult Student Retention and Achievement with Language-Based Modular Materials. POR FIN: Program Organizing Related Family Instruction in the Neighborhood.

    ERIC Educational Resources Information Center

    Bexar County School Board, San Antonio, TX.

    The goal of the POR FIN research design was to develop a language-based curriculum emphasizing the audiolingual approach and integrating academic and social-functioning subject matter. The modular curriculum is designed so that each lesson is independent and complete in itself, and provides a high degree of motivation, retention, and achievement…

  11. P(O)R2-directed Pd-catalyzed C–H functionalization of biaryl derivatives to synthesize chiral phosphorous ligands

    PubMed Central

    Hu, Rong-Bin; Wang, Hong-Li; Zhang, Hong-Yu; Zhang, Heng; Ma, Yan-Na

    2014-01-01

    Summary Chiral phosphorus ligands have been widely used in transition metal-catalyzed asymmetric reactions. Herein, we report a new synthesis approach of chiral biaryls containing a phosphorus moiety using P(O)R2-directed Pd-catalyzed C–H activation; the functionalized products are produced with good enantioselectivity. PMID:25246966

  12. El proceso hacia la integracion de la equidad por genero al curriculo.(The Process of the Integration of Gender Equity in the Curriculum.)

    ERIC Educational Resources Information Center

    Rivera-Bermudez, Carmen D.

    "El Proyecto Colaborativo de Equidad por Genero en la Educacion," or the Collaborative Project for Gender Equity in Education, was undertaken in Puerto Rico between 1990 and 1992 to study how to facilitate the integration of gender equity themes in the curriculum through the direct action of participating teachers. A study examined the attitudes…

  13. Informe a la nación indica que los índices de muertes por cáncer siguen bajando

    Cancer.gov

    Los índices de mortalidad por todos los cánceres combinados para hombres, mujeres y niños siguieron bajando en Estados Unidos entre 2004 y 2008, según el Informe Anual a la Nación sobre el Estado del Cáncer de 1975 a 2008. El índice general de diagnóstico

  14. Reconciling Scale Mismatch in Water Governance, Hydro-climatic Processes and Infrastructure Systems of Water Supply in Las Vegas

    NASA Astrophysics Data System (ADS)

    Garcia, M. E.; Alarcon, T.; Portney, K.; Islam, S.

    2013-12-01

    Water resource systems are a classic example of a common pool resource due to the high cost of exclusion and the subtractability of the resource; for common pool resources, the performance of governance systems primarily depends on how well matched the institutional arrangements and rules are to the biophysical conditions and social norms. Changes in water governance, hydro-climatic processes and infrastructure systems occur on disparate temporal and spatial scales. A key challenge is the gap between current climate change model resolution, and the spatial and temporal scale of urban water supply decisions. This gap will lead to inappropriate management policies if not mediated through a carefully crafted decision making process. Traditional decision support and planning methods (DSPM) such as classical decision analysis are not equipped to deal with a non-static climate. While emerging methods such as decision scaling, robust decision making and real options are designed to deal with a changing climate, governance systems have evolved under the assumption of a static climate and it is not clear if these methods are well suited to the existing governance regime. In our study, these questions are contextualized by examining an urban water utility that has made significant changes in policy to adapt to changing conditions: the Southern Nevada Water Authority (SNWA) which serves metropolitan Las Vegas. Like most desert cities, Las Vegas exists because of water; the artesian springs of the Las Vegas Valley once provided an ample water supply for Native Americans, ranchers and later a small railroad city. However, population growth has increased demands far beyond local supplies. The area now depends on the Colorado River for the majority of its water supply. Natural climate variability with periodic droughts has further challenged water providers; projected climate changes and further population growth will exacerbate these challenges. Las Vegas is selected as a case

  15. Community-based education in nutrition and cancer: the Por La Vida Cuidándome curriculum.

    PubMed

    Navarro, A M; Rock, C L; McNicholas, L J; Senn, K L; Moreno, C

    2000-01-01

    The Por La Vida (PLV) intervention model relies on community lay health advisors trained to conduct education sessions among members of their existing social networks. PLV Cuidándome was funded by the NCI to develop, implement, and evaluate the PLV model with respect to nutrition and cancer prevention, as well as early detection of breast and cervical cancers. The target population is the Latino community, for which substantial barriers to health care access exist. This article presents the curriculum that guides the sessions and describes its development, which was based on semi-structured interviews with Latina lay-health community workers to explore relevant attitudes and behaviors. Also key to the process was the work of the educational materials committee, whose members offered community representation as well as expertise in nutritional sciences, educational technologies, and community-based health promotion interventions and research. The 12-session curriculum's goal was to increase both the variety and the quality of fruits and/or vegetables consumed. It included information about consumption of fiber and fat in the importance of balance between energy intake and physical activity. The program has been well received. An ongoing study examines how it enhances nutrition and cancer prevention. PMID:11019766

  16. A Proposed Activity for a Meaningful Learning about the Moon Phases. (Breton Title: Uma Proposta de Atividade Para a Aprendizagem Significativa sobre as Fases da Lua.) Una Actividad Propuesta Para EL Aprendizaje Significativo Acerca de Las Fases de la Luna

    NASA Astrophysics Data System (ADS)

    Martins, Bruno Andrade; Langhi, Rodolfo

    2012-12-01

    ínua avaliação durante o processo, culmina com a elaboração de uma história em quadrinhos envolvendo as fases da Lua. Portanto, o objetivo deste trabalho é apresentar uma proposta de atividade didática diferenciada sustentada pelos princípios teóricos da aprendizagem significativa aplicada ao ensino das fases da Lua durante as aulas de Física no ensino médio. En este trabajo se presenta uno de los contenidos de la Astronomía y el evidente fracaso en la enseñanza del tema en la escuela secundaria, a pesar del hecho que los documentos oficiales apuntan para la necesidad de trabajar contenidos de Astronomía en este nivel. Entre los conceptos alternativos en Astronomía que los alumnos secundarios llevan consigo, aún después de terminados los estudios, destacamos aquí el fenómeno de las fases de la Luna. El desarrollo de diferentes estrategias en relación con los métodos tradicionales, dirigidas al proceso de enseñanza-aprendizaje en este tema fue considerado en este trabajo como uno de los resultados obtenidos a la luz de los referenciales del aprendizaje significativo, tal como fueron fundamentados por Ausubel. Según la propuesta que aquí se presenta, la participación activa de los estudiantes en la ejecución de una actividad experimental y otras actividades educativas destinadas a la evaluación continua durante el proceso culminó en la elaboración de una historieta respecto de las fases de la Luna. Por lo tanto, el objetivo de este trabajo es presentar una propuesta de actividad de enseñanza diferenciada con el apoyo de los principios teóricos del aprendizaje significativo aplicado a la enseñanza de las fases de la luna durante las clases de física del ciclo secundario.

  17. Ciencia, Sociedad, Soluciones: Una Introduccion al USGS

    USGS Publications Warehouse

    U.S. Geological Survey

    2001-01-01

    El USGS sirve a la nacion de los Estados Unidos proveyendo informacion fidedigna para ? Describir y comprender la Tierra; ? Minimizar la perdida de vidas y propiedades por desastres naturales; ? Manejar los recursos hidrologicos, biologicos, energeticos y minerales; y ? Mejorar y proteger nuestra calidad de vida.

  18. Seepage carbonate mounds in Cenozoic sedimentary sequences from the Las Minas Basin, SE Spain

    NASA Astrophysics Data System (ADS)

    Pozo, M.; Calvo, J. P.; Scopelliti, G.; González-Acebrón, L.

    2016-04-01

    A number of carbonate mounds composed of indurate, strongly folded and/or brecciated calcite and dolomite beds occur interstratified in Cenozoic sedimentary sequences from the Las Minas Basin. Part of the fabric of the rock forming the carbonate mounds is composed of laminated to banded dolostone similar to the host rock but showing contrasted lithification. Moreover, the carbonate deposits of the mounds display aggrading neomorphism of dolomite, partial replacement of dolomite by calcite, calcite cementation, and extensive silicification, locally resulting in box-work fabric. Eight main lithofacies were distinguished in the carbonate mound deposits. In some lithofacies, chert is present as both microcrystalline to fibro-radial quartz and opal, the latter occurring mainly as cement whereas the former replace the carbonate and infill voids. Yet one of the carbonate mounds shows distinctive petrography and geochemical features thus suggesting a distinctive growth pattern. The carbon isotope compositions of calcite from the mound samples range from - 11.56 to - 5.15 δ‰ whilst dolomite is depleted in 13C, with values of - 12.38 to 3.02 δ‰. Oxygen isotopic compositions vary from - 9.42 to - 4.64 δ‰ for calcite and between - 6.68 and 8.19 δ‰ for dolomite. Carbonate in the mounds shows significant enrichment in Co, Cr, Ni and Pb content, especially in the strongly deformed (F-2-2 lithofacies) and brecciated carbonate (F-4). The carbonate deposits show depletion in REE and Y in contrast to that determined in lutite. The formation of the carbonate mounds was related to local artesian seepage thermal water flows of moderate to relative high temperatures. Pressure differences between the low permeability host rock and the circulating fluids accounted for dilational fracturing and brecciation of the host sediment packages, which combined with precipitation of new carbonate and silica mineral phases. Locally, some carbonate mounds developed where groundwater

  19. Geohydrologic reconnaissance of Lake Mead National Recreation Area; Las Vegas Wash to Opal Mountain, Nevada

    USGS Publications Warehouse

    Laney, R.L.

    1981-01-01

    The study is a geohydrologic reconnaissance of about 170 square miles in the Lake Mead National Recreation Area from Las Vegas Wash to Opal Mountain, Nevada. The study is one of a series that describes the geohydrology of the recreation area and that indentifies areas where water supplies can be developed. Precipitation in this arid area is about 5 inches per year. Streamflow is seasonal and extremely variable except for that in the Colorado River, which adjoins the area. Pan evaporation is more than 20 times greater than precipitation; therefore, regional ground-water supplies are meager except near the Colorado River, Lake Mead, and Lake Mohave. Large ground-water supplies can be developed near the river and lakes, and much smaller supplies may be obtained in a few favorable locations farther from the river and lakes. Ground water in most of the areas probably contains more than 1,000 milligrams per liter of dissolved solids, but water that contains less than 1,000 milligrams per liter of dissolved solids can be obtained within about 1 mile of the lakes. Crystalline rocks of metamorphic, intrusive and volcanic origin crop out in the area. These rocks are overlain by conglomerate and mudstone of the Muddy Creek Formation, gravel and conglomerate of the older alluvium, and sand and gravel of the Chemehuevi Formation and younger alluvium. The crystalline rocks, where sufficiently fractured, yield water to springs and would yield small amounts of water to favorably located wells. The poorly cemented and more permeable beds of the older alluvium, Chemehuevi Formation, and younger alluvium are the better potential aquifers, particularly along the Colorado River and Lakes Mead and Mohave. Thermal springs in the gorge of the Colorado River south of Hoover Dam discharge at least 2,580 acre-feet per year of water from the volcanic rocks and metamorphic and plutonic rocks. The discharge is much greater than could be infiltrated in the drainage basin above the springs

  20. Las Cumbres Observatory Global Telescope Network: Keeping Education in the Dark

    NASA Astrophysics Data System (ADS)

    Ross, R. J.

    2011-09-01

    Las Cumbres Observatory Global Telescope Network (LCOGT) is creating a network of telescopes to be placed around the world providing 24/7 sky coverage of both the Northern and Southern hemispheres. These telescopes will range in size from 0.4 m to 2.0 m and will be available for scientific and educational uses in both real-time and in a queue-scheduler. The educational uses of LCOGT will be primarily online through our website (http://www.lcogt.net) where there will be how-to guides, ideas for activities, opportunities for participating in research projects with our astronomers, full access to the public archive, as well as an online community built through forums and groups. Content will be visible to all, although registered users will have the ability to add resources, post on blogs and forums, comment and rate existing pages and resources, collaborate in world-wide projects, and much more. The current network includes the two 2.0 m Faulkes Telescopes on Haleakala, Maui and at Siding Spring, Australia. A 0.8 m telescope located at Sedgwick Reserve in the Santa Ynez Valley is nearly commissioned and will be used both for local outreach events as well as on the LCOGT network. The first pair of 0.4 m telescopes has been deployed to Maui and are enclosed inside the clamshell dome with Faulkes Telescope North (FTN), but still have some time to go before they are fully commissioned. The site in Chile is currently being prepped for three 1.0 m and two pairs of 0.4 m telescopes with the site in South Africa to follow shortly. Other sites include the Canary Islands, a site in North America, one in Asia, and another site in Australia. The 0.4 m telescopes will be deployed by pair and the 1.0 m telescopes will be deployed in groups of two or three, all with research-grade instrumentation.

  1. Las Cumbres Observatory Global Telescope Network: Keeping Citizen Scientists in the Dark

    NASA Astrophysics Data System (ADS)

    Ross, R. J.

    2012-08-01

    Las Cumbres Observatory Global Telescope Network (LCOGT) is creating a network of telescopes at excellent sites around the world providing 24/7 all sky coverage for astronomical observations. The network of telescopes, ranging in size from 0.4 m to 2.0 m, will be available for both scientific and education users. The LCOGT telescopes are being built quickly and will be deployed soon. The two 2.0 m Faulkes Telescopes, one on Haleakala, Maui (FTN), the other at Siding Spring Observatory, Australia (FTS), are currently in operation. There is also a 0.8 m telescope in the Santa Ynez Valley, California (BOS), which is being used for commissioning and for many local outreach programs. The first 1.0 m telescopes will be heading to Chile and South Africa in 2011 and will each be accompanied by a 0.4 m telescope. Other sites, including Tenerife (Canary Islands, Spain), McDonald Observatory (Texas), Siding Spring (Australia), and Haleakala (Hawaii) will follow, with the possibility of up to two additional sites yet to be selected. The LCOGT education and public outreach effort is transforming into a "Citizen Science" program. Several projects will encompass taking observations through the network, analyzing the data, and sharing the results with other citizen scientists from around the world. The first of these projects, "Agent Exoplanet," will be launched in mid-2011, and will involve analyzing brand-new data to create a light curve of an exoplanet. As the network is not yet complete, this test project will not include actual observing as future ones will. More information about LCOGT and its Citizen Science program can be found online (http://www.lcogt.net). In addition to material to get started in the Citizen Science program, the website also includes resources and content for more hands-on activities using archived data, general astronomy pages, network information, complete access to the public data archive, current news, and recent publications. And don't forget to

  2. Laser Remote Measurements of atmospheric pollutants (Las-R-Map): UV-Visible Laser system description and data processing

    NASA Astrophysics Data System (ADS)

    Sivakumar, V.; Wyk, H. V.

    Laser radar more popularly known as LIDAR LIght Detection And Ranging is becoming one of the most powerful techniques for active remote sensing of the earth s atmosphere Around the globe several new lidar systems have been developed based on the scientific interest Particularly the DIfferential Absorption Lidar DIAL technique is only one which can provide the better accuracy of measuring atmospheric pollutants Using modern advanced techniques and instrumentation a mobile DIAL system called laser remote measurements of atmospheric pollutants hear after referred as Las-R-Map is designed at National Laser Centre NLC --Pretoria 25 r 45 prime S 28 r 17 prime E Las-R-Map is basically used for measuring atmospheric pollutants applying the principle of absorption by constituents The system designed primarily to focus on the following pollutant measurements such as SO 2 CH 4 CO 2 NO 2 and O 3 In future the system could be used to measure few particulate matter between 2 5 mu m and 10 mu m Benzene Hg 1 3-butadiene H 2 S HF and Volatile Organic Compounds VOC Las-R-map comprises of two different laser sources Alexandrite and CO 2 optical receiver data acquisition and signal processor It uses alexandrite laser in the UV-Visible region from 200 nm to 800 nm and CO 2 laser in the Far-IR region from 9 2 mu m to 10 8 mu m Such two different laser sources make feasibility for studying the wide range of atmospheric pollutants The present paper is focused on technical details

  3. Hydrostratigraphic Framework of the Raton, Vermejo, and Trinidad Aquifers in the Raton Basin, Las Animas County, Colorado

    USGS Publications Warehouse

    Watts, Kenneth R.

    2006-01-01

    Exploration for and production of coalbed methane has increased substantially in the Rocky Mountain region of the United States since the 1990s. During 1999-2004, annual production of natural gas (coalbed methane) from the Raton Basin in Las Animas County, Colorado, increased from 28,129,515 to 80,224,130 thousand cubic feet, and the annual volume of ground water coproduced by coalbed methane wells increased from about 949 million gallons to about 2,879 million gallons. Better definition of the hydrostratigraphic framework of the Raton, Vermejo, and Trinidad aquifers in the Raton Basin of southern Colorado is needed to evaluate the long-term effects of coalbed methane development on the availability and sustainability of ground-water resources. In 2001, the U.S. Geological Survey, in cooperation with the Colorado Water Conservation Board, began a study to evaluate the hydrogeology of the Raton Basin in Huerfano and Las Animas Counties, Colorado. Geostatistical methods were used to map the altitude of and depths to the bottoms and tops (structure) and the apparent thicknesses of the Trinidad Sandstone, the Vermejo Formation, and the Raton Formation in Las Animas County, based on completion reports and drillers' logs from about 1,400 coalbed methane wells in the Raton Basin. There was not enough subsurface control to map the structural surfaces and apparent thicknesses of the aquifers in Huerfano County. Geostatistical methods also were used to map the regional water table in the northern part of Las Animas County, based on reported depth to water from completion reports of water-supply wells. Although these maps were developed to better define the hydrostratigraphic framework, they also can be used to determine the contributing aquifer(s) of existing water wells and to estimate drilling depths of proposed water wells. These maps of the hydrostratigraphic framework could be improved with the addition of measured sections and mapping of geologic contacts at outcrops

  4. Distress in the Desert: Neighborhood Disorder, Resident Satisfaction, and Quality of Life during the Las Vegas Foreclosure Crisis

    PubMed Central

    Batson, Christie D.; Monnat, Shannon M.

    2014-01-01

    Using surveys collected from a sample of households nested within ‘naturally occurring’ neighborhoods in Las Vegas, NV during the 2007-2009 economic recession, this study examines the associations between real and perceived measures of neighborhood distress (foreclosure rate, physical decay, crime) and residents' reports of neighborhood quality of life and neighborhood satisfaction. Consistent with social disorganization theory, both real and perceived measures of neighborhood disorder were negatively associated with quality of life and neighborhood satisfaction. Residents' perceptions of neighborliness partially acted as a buffer against the effects of neighborhood distress, including housing foreclosures, on quality of life and neighborhood satisfaction. PMID:25750507

  5. Assessment of Residential Biomass Burning During Winter in Las Vegas, Nevada

    NASA Astrophysics Data System (ADS)

    Brown, S. G.; Lee, T.; Olson, D.; Norris, G.; Roberts, P. T.; Collett, J. L.

    2011-12-01

    Concentrations of organic matter (OM) and black carbon (BC) were measured at a site in a residential area of Las Vegas, Nevada, and multiple analytical methods were used to determine the amounts attributable to biomass burning. In January 2008, measurements of a wood burning tracer, levoglucosan, were made via gas chromatography-mass spectroscopy (n=17). In addition, an Aerodyne High Resolution Aerosol Mass Spectrometer (HR-AMS) measured OM and C2H4O2+, a levoglucosan-derived fragment. During 2007 and 2008, two-channel Aethalometer data were also collected; the difference between the 370 nm and 880 nm channels (UV-BC difference) was used to indicate the presence of wood smoke. Concentrations of OM, BC, C2H4O2+, and levoglucosan, as well as the UV-BC difference, were all highest during the evening hours (generally between 1800 and 0000 LST). Average OM concentrations were 3.3 μg/m3 during January but were 6.9 μg/m3 during the overnight hours (between 1700 and 0000 LST). Median levoglucosan concentrations were 0.14 μg/m3. The correlation of levoglucosan with C2H4O2+ was very high (r2=0.92). During the evening hours, correlation between BC and C2H4O2+ was good (r2=0.79); however, correlation was poor during other hours (r2<0.40), suggesting that other emissions such as mobile-source emissions were likely the dominant source of BC during those hours. C2H4O2+ showed modest correlation with UV-BC (e.g., r2=0.45). Using EPA's positive matrix factorization tool, EPA PMF, on the January HR-AMS data, we determined that biomass burning organic aerosol (BBOA) constituted 12% of the OM on average, but about 25% of the OM during evening hours. BBOA correlated well with levoglucosan (r2=0.82) and C2H4O2+ (r2=0.93). Levoglucosan measurements suggested that wood burning could constitute 38% of the OM during the overnight periods on average, although this number greatly depends on the assumed ratio of levoglucosan to OM in a source profile for residential biomass burning. The

  6. Las Palmeras Molecular Dynamics: A flexible and modular molecular dynamics code

    NASA Astrophysics Data System (ADS)

    Davis, Sergio; Loyola, Claudia; González, Felipe; Peralta, Joaquín

    2010-12-01

    Las Palmeras Molecular Dynamics (LPMD) is a highly modular and extensible molecular dynamics (MD) code using interatomic potential functions. LPMD is able to perform equilibrium MD simulations of bulk crystalline solids, amorphous solids and liquids, as well as non-equilibrium MD (NEMD) simulations such as shock wave propagation, projectile impacts, cluster collisions, shearing, deformation under load, heat conduction, heterogeneous melting, among others, which involve unusual MD features like non-moving atoms and walls, unstoppable atoms with constant-velocity, and external forces like electric fields. LPMD is written in C++ as a compromise between efficiency and clarity of design, and its architecture is based on separate components or plug-ins, implemented as modules which are loaded on demand at runtime. The advantage of this architecture is the ability to completely link together the desired components involved in the simulation in different ways at runtime, using a user-friendly control file language which describes the simulation work-flow. As an added bonus, the plug-in API (Application Programming Interface) makes it possible to use the LPMD components to analyze data coming from other simulation packages, convert between input file formats, apply different transformations to saved MD atomic trajectories, and visualize dynamical processes either in real-time or as a post-processing step. Individual components, such as a new potential function, a new integrator, a new file format, new properties to calculate, new real-time visualizers, and even a new algorithm for handling neighbor lists can be easily coded, compiled and tested within LPMD by virtue of its object-oriented API, without the need to modify the rest of the code. LPMD includes already several pair potential functions such as Lennard-Jones, Morse, Buckingham, MCY and the harmonic potential, as well as embedded-atom model (EAM) functions such as the Sutton-Chen and Gupta potentials. Integrators to

  7. Morphology and mechanics of large collapses: Sotano de las Golondrinas, Mexico

    NASA Astrophysics Data System (ADS)

    Lauritzen, S.-E.; Hammer, Ø.; Wheeler, W.; Redfield, T.; Blanco, M.; Rosales Lagarde, L.; Jamtveit, B.

    2012-04-01

    The dynamics and mode of formation of large karst pipes are not yet fully understood. We present precise Lidar and structural field data of the 340+ m deep open karst shaft el Sotano de las Golondrinas, and test the geometry on a a simplified 2D evolution model. The Golondrinas shaft is located in the San Luis county, northeastern México and is developed in massive, early cretaceous (Barremian-Coniacian) reef- limestones (El Abra/ El Doctor fm.). It is a bell-shaped breakout dome that has reached the land surface, i.e. a classical Einstrurtzdoline. The dimensions and shape makes it to an interesting case study, as it has similar dimensions as breccia-pipes encountered in many paleokarsts, but is incompletely filled, so that internal structure can be easily inspected. Second, with regard to stress mechanisms controlling roof collapse, the large dimensions (270 - 130 m diameter at the base) reduce the influence (anisotropy) of geological structures in comparison to smaller pipes (e.g. <70 m diameter). We may thus test morphology against the shape of various tectonic and gravitational stress distributions. During our field campaign in 2009, it was decided to re-map the cavity using laser (Lidar and rangefinders) in order to obtain exact dimensions and high-resolution images of morphology and geologic structure. The maximum explored depth is a fissure at -512 m with the main floor between 325 and 400 meters below the skylight entrance of 80 m diameter. Overall, the shaft is cigar-shaped and oval in outline. Its horizontal length/width ratio at floor level is about 2.31, with an azimuth of elongation of about 125 degrees true. The shaft is developed along a major, steep fracture zone (115°, true) which makes up the north wall. The fracture has no detectable off-set, in all very few faults were observed. The strike of the guiding fracture, the azimuth of elongation and the direction of the least horizontal stress direction (111°, true) coincide. Where it occurs

  8. Study of the interaction mechanisms between absorbed NO{sub 2} and por-Si/SnO{sub x} nanocomposite layers

    SciTech Connect

    Bolotov, V. V.; Kan, V. E. Makushenko, R. K.; Biryukov, M. Yu.; Ivlev, K. E.; Roslikov, V. E.

    2013-10-15

    The interaction mechanisms between NO{sub 2} molecules and the surface of por-Si/SnO{sub x} nanocomposites obtained by magnetron deposition and chemical vapor deposition (CVD) are studied by infrared absorption spectroscopy and electron paramagnetic resonance methods. The observed increase in the free carrier concentration in the por-Si/SnO{sub x} nanocomposite layers is explained by a change in the charge state of P{sub b} centers due to the formation of neutral 'surface defect-adsorbed NO{sub 2} molecule' complexes with free carrier generation in the crystallite bulk. In the nanocomposite layers grown by the CVD method, the increase in the free hole concentration during NO{sub 2} adsorption is much less pronounced in comparison with the composite grown by magnetron deposition, which is caused by the competing interaction channel of NO{sub 2} molecules with electrically neutral P{sub b} centers.

  9. Novel Inhibitors of the Pseudomonas aeruginosa Virulence Factor LasB: a Potential Therapeutic Approach for the Attenuation of Virulence Mechanisms in Pseudomonal Infection▿†§

    PubMed Central

    Cathcart, George R. A.; Quinn, Derek; Greer, Brett; Harriott, Pat; Lynas, John F.; Gilmore, Brendan F.; Walker, Brian

    2011-01-01

    Pseudomonas elastase (LasB), a metalloprotease virulence factor, is known to play a pivotal role in pseudomonal infection. LasB is secreted at the site of infection, where it exerts a proteolytic action that spans from broad tissue destruction to subtle action on components of the host immune system. The former enhances invasiveness by liberating nutrients for continued growth, while the latter exerts an immunomodulatory effect, manipulating the normal immune response. In addition to the extracellular effects of secreted LasB, it also acts within the bacterial cell to trigger the intracellular pathway that initiates growth as a bacterial biofilm. The key role of LasB in pseudomonal virulence makes it a potential target for the development of an inhibitor as an antimicrobial agent. The concept of inhibition of virulence is a recently established antimicrobial strategy, and such agents have been termed “second-generation” antibiotics. This approach holds promise in that it seeks to attenuate virulence processes without bactericidal action and, hence, without selection pressure for the emergence of resistant strains. A potent inhibitor of LasB, N-mercaptoacetyl-Phe-Tyr-amide (Ki = 41 nM) has been developed, and its ability to block these virulence processes has been assessed. It has been demonstrated that thes compound can completely block the action of LasB on protein targets that are instrumental in biofilm formation and immunomodulation. The novel LasB inhibitor has also been employed in bacterial-cell-based assays, to reduce the growth of pseudomonal biofilms, and to eradicate biofilm completely when used in combination with conventional antibiotics. PMID:21444693

  10. Novel inhibitors of the Pseudomonas aeruginosa virulence factor LasB: a potential therapeutic approach for the attenuation of virulence mechanisms in pseudomonal infection.

    PubMed

    Cathcart, George R A; Quinn, Derek; Greer, Brett; Harriott, Pat; Lynas, John F; Gilmore, Brendan F; Walker, Brian

    2011-06-01

    Pseudomonas elastase (LasB), a metalloprotease virulence factor, is known to play a pivotal role in pseudomonal infection. LasB is secreted at the site of infection, where it exerts a proteolytic action that spans from broad tissue destruction to subtle action on components of the host immune system. The former enhances invasiveness by liberating nutrients for continued growth, while the latter exerts an immunomodulatory effect, manipulating the normal immune response. In addition to the extracellular effects of secreted LasB, it also acts within the bacterial cell to trigger the intracellular pathway that initiates growth as a bacterial biofilm. The key role of LasB in pseudomonal virulence makes it a potential target for the development of an inhibitor as an antimicrobial agent. The concept of inhibition of virulence is a recently established antimicrobial strategy, and such agents have been termed "second-generation" antibiotics. This approach holds promise in that it seeks to attenuate virulence processes without bactericidal action and, hence, without selection pressure for the emergence of resistant strains. A potent inhibitor of LasB, N-mercaptoacetyl-Phe-Tyr-amide (K(i) = 41 nM) has been developed, and its ability to block these virulence processes has been assessed. It has been demonstrated that thes compound can completely block the action of LasB on protein targets that are instrumental in biofilm formation and immunomodulation. The novel LasB inhibitor has also been employed in bacterial-cell-based assays, to reduce the growth of pseudomonal biofilms, and to eradicate biofilm completely when used in combination with conventional antibiotics. PMID:21444693

  11. Subsurface Connections and Magma Mixing as revealed by Olivine- and Pyroxene-Hosted Melt Inclusions from Cerro Negro Volcano and the Las Pilas-El Hoyo Complex, Nicaragua.

    NASA Astrophysics Data System (ADS)

    Venugopal, S.; Moune, S.; Williams-Jones, G.

    2015-12-01

    Cerro Negro, the youngest volcano in the Central American Volcanic Belt, is a polygenetic cinder cone with relatively frequent explosive basaltic eruptions. Las Pilas, on the other hand, is a much larger and older complex with milder and less frequent eruptions. Based on historical data, these two closely spaced volcanoes have shown concurrent eruptive behavior, suggesting a subsurface connection. To further investigate this link, melt inclusions, which are blebs of melt trapped in growing crystals, were the obvious choice for optimal comparison of sources and determination of pre-eruptive volatile contents and magmatic conditions. Olivine-hosted inclusions were chosen for both volcanoes and pyroxene-hosted inclusions were also sampled from Las Pilas to represent the evolved melt. Major, volatile and trace elements reveal a distinct geochemical continuum with Cerro Negro defining the primitive end member and Las Pilas representing the evolved end member. Volatile contents are high for Cerro Negro (up to 1260 ppm CO2, 4.27 wt% H2O and 1700 ppm S) suggesting that volatile exsolution is likely the trigger for Cerro Negro's explosive eruptions. Las Pilas volatile contents are lower but consistent with degassing and evolutionary trends shown by major oxides. Trace element contents are rather unique and suggest Cerro Negro magmas fractionally crystallize while Las Pilas magmas are the products of mixing. Magmatic conditions were estimated with major and volatile contents: at least 2.4 kbar and 1170 °C for Cerro Negro melts and 1.3 kbar and 1130 °C for Las Pilas melts with an overall oxygen fugacity at the NNO buffer. In combination with available literature data, this study suggests an interconnected subsurface plumbing system and thus Cerro Negro should be considered as the newest vent within the Las Pilas-El Hoyo Complex.

  12. Hacia el consumo informado de tabaco en México: efecto de las advertencias con pictogramas en población fumadora

    PubMed Central

    Thrasher, James F; Pérez-Hernández, Rosaura; Arillo-Santillán, Edna; Barrientos-Gutiérrez, Inti

    2015-01-01

    Resumen Objetivo Evaluar el efecto de las advertencias sanitarias (AS) con pictogramas en las cajetillas de tabaco en adultos fumadores. Material y métodos Cohorte de fumadores con representatividad poblacional de siete ciudades mexi canas, antes (2010) y después (2011) de la implementación de AS con pictogramas (ASP). Para determinar el cambio en las variables sobre el impacto cognitivo y conductual de las advertencias, se estimaron modelos bivariados y ajustados de ecuaciones de estimación generalizada. En el Segundo levantamiento (2011), se estimaron modelos para determiner los factores que se asocian con el reporte de recordar cada advertencia que había entrado al mercado, además de los factores asociados con el autorreporte del impacto de cada advertencia vigente. Resultados Se observaron incrementos importantes de 2010 a 2011 en los conocimientos sobre los riesgos de fumar, los componentes tóxicos del tabaco y el número telefónico para recibir consejos sobre dejar de fumar. La recordación e impacto de las primeras advertencias con pictogramas parecen ser amplios y equitativos a través de la población fumadora. En comparación con 2010, un mayor nivel de ex fumadores entrevistados en 2011 reportaron que las advertencias habían influido mucho en dejar de fumar (RM=2.44, 95% IC 1.27–4.72). Conclusiones Las AS con pictogramas han logrado un impacto importante en el conocimiento y conducta, información relevante para la población y en tomadores de decisiones. PMID:22689162

  13. Vrp1p-Las17p interaction is critical for actin patch polarization but is not essential for growth or fluid phase endocytosis in S. cerevisiae.

    PubMed

    Wong, Ming Hwa; Meng, Lei; Rajmohan, Rajamuthiah; Yu, Shangjuan; Thanabalu, Thirumaran

    2010-12-01

    Vrp1p (yeast WIP) forms a protein complex with Las17p (yeast WASP), however the physiological significance of the interaction has not been fully characterized. Vrp1p residues, (788)MPKPR(792) are essential for Vrp1p-Las17p interaction. While C-Vrp1p(364-817) complements all the defects of the vrp1Δ strain, C-Vrp1p(364-817)(5A) ((788)AAAAA(792)) does not complement any of the defects, due to its inability to localize to cortical patches. Targeting C-Vrp1p(364-817)(5A) to membranes using CAAX motif (C-Vrp1p(364-817)(5A)-CAAX) rescued the growth and endocytosis defect but not the actin patch polarization defect of vrp1Δ. Vrp1p can localize to cortical patches, either by binding to Las17p through LBD (Las17 Binding Domain, Vrp1p(760-817)) or independent of Las17p through residues in N-Vrp1p(1-364). Unlike Vrp1p, Vrp1p(5A) localizes poorly to cortical patches and complements all the defects of vrp1Δ strain except actin patch polarization at elevated temperature. N-Vrp1p(1-364) complements all the defects of vrp1Δ strain except the actin patch polarization defect while N-Vrp1p(1-364)-LBD fusion protein complements all the defects. Thus our results show that while both Vrp1p and Las17p are essential for many cellular processes, the two proteins do not necessarily have to bind to each other to carry out these cellular functions. However, Las17p-Vrp1p interaction is essential for actin patch polarization at elevated temperature. PMID:20816901

  14. Binding of Complement Factor H to PorB3 and NspA Enhances Resistance of Neisseria meningitidis to Anti-Factor H Binding Protein Bactericidal Activity

    PubMed Central

    Giuntini, Serena; Pajon, Rolando; Ram, Sanjay

    2015-01-01

    Among 25 serogroup B Neisseria meningitidis clinical isolates, we identified four (16%) with high factor H binding protein (FHbp) expression that were resistant to complement-mediated bactericidal activity of sera from mice immunized with recombinant FHbp vaccines. Two of the four isolates had evidence of human FH-dependent complement downregulation independent of FHbp. Since alternative complement pathway recruitment is critical for anti-FHbp bactericidal activity, we hypothesized that in these two isolates binding of FH to ligands other than FHbp contributes to anti-FHbp bactericidal resistance. Knocking out NspA, a known meningococcal FH ligand, converted both resistant isolates to anti-FHbp susceptible isolates. The addition of a nonbactericidal anti-NspA monoclonal antibody to the bactericidal reaction also increased anti-FHbp bactericidal activity. To identify a role for FH ligands other than NspA or FHbp in resistance, we created double NspA/FHbp knockout mutants. Mutants from both resistant isolates bound 10-fold more recombinant human FH domains 6 and 7 fused to Fc than double knockout mutants prepared from two sensitive meningococcal isolates. In light of recent studies showing functional FH-PorB2 interactions, we hypothesized that PorB3 from the resistant isolates recruited FH. Allelic exchange of porB3 from a resistant isolate to a sensitive isolate increased resistance of the sensitive isolate to anti-FHbp bactericidal activity (and vice versa). Thus, some PorB3 variants functionally bind human FH, which in the presence of NspA enhances anti-FHbp resistance. Combining anti-NspA antibodies with anti-FHbp antibodies can overcome resistance. Meningococcal vaccines that target both NspA and FHbp are likely to confer greater protection than either antigen alone. PMID:25644002

  15. Los índices de mortalidad por cáncer de pulmón siguen en descenso y contribuyen a la continua reducc

    Cancer.gov

    El Informe Anual a la Nación sobre el Estado del Cáncer (1975 a 2010), mostró un descenso más acelerado que en años anteriores de los índices de mortalidad por cáncer de pulmón. También contiene una sección especial que destaca los efectos significativos

  16. La doctora Amelie Ramírez y la investigación de desigualdades de salud por cáncer en la comunidad la

    Cancer.gov

    La doctora Ramírez es la investigadora principal de Redes en Acción, un centro del programa de redes comunitarias subvencionado por el NCI que se propone reducir la incidencia del cáncer en la comunidad latina a través de una red nacional de grupos comunitarios, investigadores, agencias de salud gubernamentales y la población en general.

  17. Adjuvant Effects Elicited by Novel Oligosaccharide Variants of Detoxified Meningococcal Lipopolysaccharides on Neisseria meningitidis Recombinant PorA Protein: A Comparison in Mice

    PubMed Central

    Mehta, Ojas H.; Norheim, Gunnstein; Hoe, J . Claire; Rollier, Christine S.; Nagaputra, Jerry C.; Makepeace, Katherine; Saleem, Muhammad; Chan, Hannah; Ferguson, David J. P.; Jones, Claire; Sadarangani, Manish; Hood, Derek W.; Feavers, Ian; Derrick, Jeremy P.; Pollard, Andrew J.; Moxon, E . Richard

    2014-01-01

    Neisseria meningitidis lipopolysaccharide (LPS) has adjuvant properties that can be exploited to assist vaccine immunogenicity. The modified penta-acylated LPS retains the adjuvant properties of hexa-acylated LPS but has a reduced toxicity profile. In this study we investigated whether two modified glycoform structures (LgtE and IcsB) of detoxified penta-acylated LPS exhibited differential adjuvant properties when formulated as native outer membrane vesicles (nOMVs) as compared to the previously described LgtB variant. Detoxified penta-acylated LPS was obtained by disruption of the lpxL1 gene (LpxL1 LPS), and three different glycoforms were obtained by disruption of the lgtB, lgtE or icsB genes respectively. Mice (mus musculus) were immunized with a recombinant PorA P1.7-2,4 (rPorA) protein co-administered with different nOMVs (containing a different PorA serosubtype P1.7,16), each of which expressed one of the three penta-acylated LPS glycoforms. All nOMVs induced IgG responses against the rPorA, but the nOMVs containing the penta-acylated LgtB-LpxL1 LPS glycoform induced significantly greater bactericidal activity compared to the other nOMVs or when the adjuvant was Alhydrogel. Compared to LgtE or IcsB LPS glycoforms, these data support the use of nOMVs containing detoxified, modified LgtB-LpxL1 LPS as a potential adjuvant for future meningococcal protein vaccines. PMID:25545241

  18. Binding of complement factor H to PorB3 and NspA enhances resistance of Neisseria meningitidis to anti-factor H binding protein bactericidal activity.

    PubMed

    Giuntini, Serena; Pajon, Rolando; Ram, Sanjay; Granoff, Dan M

    2015-04-01

    Among 25 serogroup B Neisseria meningitidis clinical isolates, we identified four (16%) with high factor H binding protein (FHbp) expression that were resistant to complement-mediated bactericidal activity of sera from mice immunized with recombinant FHbp vaccines. Two of the four isolates had evidence of human FH-dependent complement downregulation independent of FHbp. Since alternative complement pathway recruitment is critical for anti-FHbp bactericidal activity, we hypothesized that in these two isolates binding of FH to ligands other than FHbp contributes to anti-FHbp bactericidal resistance. Knocking out NspA, a known meningococcal FH ligand, converted both resistant isolates to anti-FHbp susceptible isolates. The addition of a nonbactericidal anti-NspA monoclonal antibody to the bactericidal reaction also increased anti-FHbp bactericidal activity. To identify a role for FH ligands other than NspA or FHbp in resistance, we created double NspA/FHbp knockout mutants. Mutants from both resistant isolates bound 10-fold more recombinant human FH domains 6 and 7 fused to Fc than double knockout mutants prepared from two sensitive meningococcal isolates. In light of recent studies showing functional FH-PorB2 interactions, we hypothesized that PorB3 from the resistant isolates recruited FH. Allelic exchange of porB3 from a resistant isolate to a sensitive isolate increased resistance of the sensitive isolate to anti-FHbp bactericidal activity (and vice versa). Thus, some PorB3 variants functionally bind human FH, which in the presence of NspA enhances anti-FHbp resistance. Combining anti-NspA antibodies with anti-FHbp antibodies can overcome resistance. Meningococcal vaccines that target both NspA and FHbp are likely to confer greater protection than either antigen alone. PMID:25644002

  19. Corynebacterium jeikeium jk0268 Constitutes for the 40 Amino Acid Long PorACj, Which Forms a Homooligomeric and Anion-Selective Cell Wall Channel

    PubMed Central

    Norouzy, Amir; Schulz, Robert; Nau, Werner M.; Kleinekathöfer, Ulrich; Tauch, Andreas; Benz, Roland

    2013-01-01

    Corynebacterium jeikeium, a resident of human skin, is often associated with multidrug resistant nosocomial infections in immunodepressed patients. C. jeikeium K411 belongs to mycolic acid-containing actinomycetes, the mycolata and contains a channel-forming protein as judged from reconstitution experiments with artificial lipid bilayer experiments. The channel-forming protein was present in detergent treated cell walls and in extracts of whole cells using organic solvents. A gene coding for a 40 amino acid long polypeptide possibly responsible for the pore-forming activity was identified in the known genome of C. jeikeium by its similar chromosomal localization to known porH and porA genes of other Corynebacterium strains. The gene jk0268 was expressed in a porin deficient Corynebacterium glutamicum strain. For purification temporarily histidine-tailed or with a GST-tag at the N-terminus, the homogeneous protein caused channel-forming activity with an average conductance of 1.25 nS in 1M KCl identical to the channels formed by the detergent extracts. Zero-current membrane potential measurements of the voltage dependent channel implied selectivity for anions. This preference is according to single-channel analysis caused by some excess of cationic charges located in the channel lumen formed by oligomeric alpha-helical wheels. The channel has a suggested diameter of 1.4 nm as judged from the permeability of different sized hydrated anions using the Renkin correction factor. Surprisingly, the genome of C. jeikeium contained only one gene coding for a cell wall channel of the PorA/PorH type found in other Corynebacterium species. The possible evolutionary relationship between the heterooligomeric channels formed by certain Corynebacterium strains and the homooligomeric pore of C. jeikeium is discussed. PMID:24116064

  20. Immunogenicity studies with a genetically engineered hexavalent PorA and a wild-type meningococcal group B outer membrane vesicle vaccine in infant cynomolgus monkeys.

    PubMed

    Rouppe van der Voort, E; Schuller, M; Holst, J; de Vries, P; van der Ley, P; van den Dobbelsteen, G; Poolman, J

    2000-01-31

    The immunogenicity of two meningococcal outer membrane vesicle (OMV) vaccines, namely the Norwegian wild-type OMV vaccine and the Dutch hexavalent PorA OMV vaccine, were examined in infant cynomolgus monkeys. For the first time, a wild-type- and a recombinant OMV vaccine were compared. Furthermore, the induction of memory and the persistence of circulating antibodies were measured. The Norwegian vaccine contained all four classes of major outer membrane proteins (OMP) and wild-type L3/L8 lipopolysaccharide (LPS). The Dutch vaccine consisted for 90% of class 1 OMPs, had low expression of class 4 and 5 OMP, and GalE LPS. Three infant monkeys were immunised with a human dose at the age of 1.5, 2.5 and 4.5 months. Two monkeys of each group received a fourth dose at the age of 11 months. In ELISA, both OMV vaccines were immunogenic and induced booster responses, particularly after the fourth immunisation. The Norwegian vaccine mostly induced sero-subtype P1.7,16 specific serum bactericidal antibodies (SBA), although some other SBA were induced as well. The antibody responses against P1.7,16, induced by the Norwegian vaccine, were generally higher than for the Dutch vaccine. However, the Dutch vaccine induced PorA specific SBA against all six sero-subtypes included in the vaccine showing differences in the magnitude of SBA responses to the various PorAs. PMID:10618530

  1. Morphology, body proportions, and postcranial hypertrophy of a female Neandertal from the Sima de las Palomas, southeastern Spain

    PubMed Central

    Walker, Michael J.; Ortega, Jon; Parmová, Klara; López, Mariano V.; Trinkaus, Erik

    2011-01-01

    Considerations of Neandertal geographical variation have been hampered by the dearth of remains from Mediterranean Europe and the absence there of sufficiently complete associated postcrania. The 2006 and 2007 excavation of an articulated partial skeleton of a small adult female Neandertal at the Sima de las Palomas, Murcia, southeastern Spain (Sima de las Palomas 96) provides substantial and secure information on body proportions among southern European Neandertals, as well as further documenting the nature of Neandertal biology in southern Iberia. The remains exhibit a suite of cranial, mandibular, dental, and postcranial features, of both Neandertals and archaic Homo generally, that distinguish them from contemporary and subsequent early modern humans. Its lower limbs exhibit the robustness of later Pleistocene Homo generally, and its upper limbs conform to the pattern of elevated robustness of the Neandertals. Its body proportions, including relative clavicular length, distal limb segment lengths, and body mass to stature indicators, conform to the “cold-adapted” pattern of more northern Neandertals. Palomas 96 therefore documents the presence of a suite of “Neandertal” characteristics in southern Iberia and, along with its small body size, the more “Arctic” body proportions of other European Neandertals despite the warmer climate of southern Iberia during marine isotope stage 3. PMID:21646528

  2. Long-term assessment of the oil spill at Bahia Las Minas, Panama. Interim report. Volume 1: Executive summary

    SciTech Connect

    Keller, B.D.; Jackson, J.B.C.

    1991-10-01

    On April 27, 1986, at least 8 million liters of medium-weight crude oil spilled from a ruptured storage tank into the Bahia Las Minas on the Caribbean Coast of Panama. Coral reefs, seagrass communities, and mangroves were affected. The area of the spill was also the location of the Smithsonian Tropical Research Institute's Galeta Laboratory where resident and visiting scientists have been studying the ecology of the Bahia Las Minas and the adjacent areas for over 15 years. Because this was a unique opportunity to assess the immediate biological effects following a major spill in the Caribbean region and to monitor the subsequent recovery, the U.S. Department of the Interior Minerals Management Service supported a 5-year environmental study. The objectives of the study are to identify any long-term changes in the marine environment that may have resulted from the spill and to understand the ecological processes causing such changes. This is the first report from the study and addresses the effects observed during the first two years of the effort.

  3. Long-term assessment of the oil spill at Bahia Las Minas, Panama. Interim report. Volume 2: Technical report

    SciTech Connect

    Keller, B.D.; Jackson, J.B.C.

    1991-10-01

    On April 27, 1986, at least 8 million liters of medium-weight crude oil spilled from a ruptured storage tank into the Bahia Las Minas on the Caribbean Coast of Panama. Coral reefs, seagrass communities, and mangroves were affected. The area of the spill was also the location of the Smithsonian Tropical Research Institute's Galeta Laboratory where resident and visiting scientists have been studying the ecology of the Bahia Las Minas and the adjacent areas for over 15 years. Because this was a unique opportunity to assess the immediate biological effects following a major spill in the Caribbean region and to monitor the subsequent recovery, the U.S. Department of the Interior Minerals Management Service supported a 5-year environmental study. The objectives of the study are to identify any long-term changes in the marine environment that may have resulted from the spill and to understand the ecological processes causing such changes. This is the first report from the study and addresses the effects observed during the first two years of the effort.

  4. An analysis of urban thermal characteristics and associated land cover in Tampa Bay and Las Vegas using Landsat satellite data

    USGS Publications Warehouse

    Xian, G.; Crane, M.

    2006-01-01

    Remote sensing data from both Landsat 5 and Landsat 7 systems were utilized to assess urban area thermal characteristics in Tampa Bay watershed of west-central Florida, and the Las Vegas valley of southern Nevada. To quantitatively determine urban land use extents and development densities, sub-pixel impervious surface areas were mapped for both areas. The urban-rural boundaries and urban development densities were defined by selecting certain imperviousness threshold values and Landsat thermal bands were used to investigate urban surface thermal patterns. Analysis results suggest that urban surface thermal characteristics and patterns can be identified through qualitatively based urban land use and development density data. Results show the urban area of the Tampa Bay watershed has a daytime heating effect (heat-source), whereas the urban surface in Las Vegas has a daytime cooling effect (heat-sink). These thermal effects strongly correlated with urban development densities where higher percent imperviousness is usually associated with higher surface temperature. Using vegetation canopy coverage information, the spatial and temporal distributions of urban impervious surface and associated thermal characteristics are demonstrated to be very useful sources in quantifying urban land use, development intensity, and urban thermal patterns. ?? 2006 Elsevier Inc. All rights reserved.

  5. On-road vehicle particulate matter and gaseous emission distributions in Las Vegas, Nevada, compared with other areas.

    PubMed

    Mazzoleni, Claudio; Kuhns, Hampden D; Moosmüller, Hans; Keislar, Robert E; Barber, Peter W; Robinson, Norman F; Watson, John G; Nikolic, Djordje

    2004-06-01

    During the spring and summer of 2000, 2001, and 2002, gaseous and particulate matter (PM) fuel-based emission factors for approximately 150,000 low-tailpipe, individual vehicles in the Las Vegas, NV, area were measured via on-road remote sensing. For the gaseous pollutants (carbon monoxide, hydrocarbons, and nitrogen oxide), a commercial vehicle emissions remote sensing system (VERSS) was used. The PM emissions were determined using a Lidar-based VERSS. Emission distributions and their shapes were analyzed and compared with previous studies. The large skewness of the distributions is evident for both gaseous pollutants and PM and has important implications for emission reduction policies, because the majority of emissions are attributed to a small fraction of vehicles. Results of this Las Vegas study and studies at other geographical locations were compared. The gaseous pollutants were found to be close to those measured by VERSS in other U.S. cities. The PM emission factors for spark ignition and diesel vehicles are in the range of previous tunnel and dynamometer studies. PMID:15242151

  6. Síndrome del Outlet Torácico: ¿Una Patología Siempre Quirúrgica? Análisis de una Serie de 31 Cirugías Realizadas por Vía Supraclavicular Serie clínica

    PubMed Central

    Socolovsky, Mariano; Di Masi, Gilda; Binaghi, Daniela; Campero, Álvaro; Páez, Miguel Domínguez; Dubrovsky, Alberto

    2014-01-01

    Introducción: El síndrome de outlet torácico es una compresión del plexo braquial que suscita polémica. Se clasifica en Outlet Torácico Verdadero o neurogénico (OTV) y Outlet Torácico Disputado o no neurogénico (OTD). El primero presenta síntomas motores en la mano, mientras que el segundo sólo síntomas sensitivos en el miembro superior. El objetivo de este trabajo es analizar los resultados obtenidos en una serie de 31 cirugías. Métodos: Se analizaron las cirugías de nervios efectuadas entre 2003-2012, tomando los diagnósticos de outlet torácico cuyo período de seguimiento post-operatorio mínimo fuera de 6 meses. Se buscaron los siguientes datos: edad, sexo, presencia de síntomas sensitivos y/o motores, clasificación, resultado de los estudios neurofisiológicos y de imágenes, resultado de la cirugía, complicaciones post-operatorias y recidivas. Resultados: Se incluyeron 31 cirugías realizadas en 30 pacientes, 9 OTV (8 mujeres) de 24.3 años, y 21 con OTD (18 mujeres) de 37.4 años de edad en promedio. Un 90% presentaron alteraciones neurofisiológicas preoperatorias, y 66,6% imagenológicas. En el intraoperatorio, el 100% de los OTV presentó una alteración anatómica relacionada con la sintomatología, hecho observado sólo en el 36.7% de los OTD operados. El 87,5% de los OTV mejoraron sensitivamente, mientras que 77,7% mejoraron la atrofia. Por el contrario, 45.4% de los OTD mejoraron permanentemente, 36.3% no tuvieron cambios, 13.6% mejoraron transitoriamente y 4.5% (un caso) empeoró. Las complicaciones post-operatorias fueron más frecuentes aunque transitorias en el grupo de OTV (3 casos sobre 9 operados, 33.3%) que en los OTD (3 casos sobre 22, un 13.6%). Conclusión: El OTV suele mayormente mejorar luego de la cirugía, igual que el OTD aunque en una proporción mucho menor. Estos hallazgos coinciden con otros reportes recientes de esta patología. PMID:25165614

  7. [Effects and mechanisms of inorganic anions in water on degradation of LAS by UV/H2 O2 combination process].

    PubMed

    Pan, Jing; Sun, Tie-Heng; Li, Hai-Bo

    2007-11-01

    Experiments are carried out to study the effects and mechanisms of inorganic anions in water on the degradation of linear alkyl benzene sulfonate (LAS) in UV/H2 O2 process. The results show that UV/H2 O2 process could remove LAS effectively, and the rate of photodegradation follows first-order reaction kinetics model. Under the condition that H2 O2 concentration was 8 mg x L(-1) and a 14 W low pressure mercury vapor discharge lamp irradiated samples, the first-order photodegradation rate constant of LAS in distilled water and tap water were 0.018 0 min(-1) and 0.012 2 min(-1) respectively. NO3-, Cl-, SO4(2-) and HCO3- have inhibitory action on LAS photodegradation. The higher inorganic anions concentration was, the stronger inhibitory action. When their concentrations were 5, 10 and 15 mmol x L(-1) respectively, their inhibitory action order was HCO3- > NO3- > Cl- > SO4(2-) all the time. It was anions synthetical effect that caused photodegradation rate constant of LAS in tap water lower than distilled water. PMID:18290479

  8. Water-quality data for the Rio Grande between Picacho Bridge near Las Cruces and Calle del Norte Bridge near Mesilla, New Mexico, 1996-97

    USGS Publications Warehouse

    Huff, G.F.

    1998-01-01

    The City of Las Cruces is concerned about water quality in a reach of the Rio Grande that receives outfall from the City of Las Cruces wastewater-treatment plant. Water-quality samples were collected from the Rio Grande at Picacho Bridge near Las Cruces, New Mexico; from the sampling site at the City of Las Cruces wastewater-treatment plant; and from the Rio Grande at Calle del Norte Bridge near Mesilla, New Mexico. The samples were collected on 12 days from August 6, 1996, to February 28, 1997, and were analyzed for a suite of dissolved and total constituents including trace metals. Instantaneous stream discharge was measured concurrently with collection of the Rio Grande samples. At the wastewater- treatment plant, the City of Las Cruces provided instantaneous discharge rates concurrent with sampling. Quality-control measures used in this study to ensure analytical accuracy included replicate sampling, replicate analysis of split samples, ambient blanks, equipment blanks, and analysis of standard reference water samples.

  9. Log ASCII Standard (LAS) Files for Geophysical Wireline Well Logs and Their Application to Geologic Cross Sections Through the Central Appalachian Basin

    USGS Publications Warehouse

    Crangle, Robert D., Jr.

    2007-01-01

    Introduction The U.S. Geological Survey (USGS) uses geophysical wireline well logs for a variety of purposes, including stratigraphic correlation (Hettinger, 2001, Ryder, 2002), petroleum reservoir analyses (Nelson and Bird, 2005), aquifer studies (Balch, 1988), and synthetic seismic profiles (Kulander and Ryder, 2005). Commonly, well logs are easier to visualize, manipulate, and interpret when available in a digital format. In recent geologic cross sections E-E' and D-D', constructed through the central Appalachian basin (Ryder, Swezey, and others, in press; Ryder, Crangle, and others, in press), gamma ray well log traces and lithologic logs were used to correlate key stratigraphic intervals (Fig. 1). The stratigraphy and structure of the cross sections are illustrated through the use of graphical software applications (e.g., Adobe Illustrator). The gamma ray traces were digitized in Neuralog (proprietary software) from paper well logs and converted to a Log ASCII Standard (LAS) format. Once converted, the LAS files were transformed to images through an LAS-reader application (e.g., GeoGraphix Prizm) and then overlain in positions adjacent to well locations, used for stratigraphic control, on each cross section. This report summarizes the procedures used to convert paper logs to a digital LAS format using a third-party software application, Neuralog. Included in this report are LAS files for sixteen wells used in geologic cross section E-E' (Table 1) and thirteen wells used in geologic cross section D-D' (Table 2).

  10. Reproductive responses of common carp (Cyprinus carpio) exposed in cages to influent of the Las Vegas Wash in Lake Mead, Nevada, from late winter to early spring.

    PubMed

    Snyder, Erin M; Snyder, Shane A; Kelly, Kevin L; Gross, Timothy S; Villeneuve, Daniel L; Fitzgerald, Scott D; Villalobos, Sergio A; Giesy, John P

    2004-12-01

    The Las Vegas Wash (LW) delivers tertiary-treated municipal wastewater effluent, nonpotable shallow groundwater seepage, and runoff from the urbanized Las Vegas Valley to Las Vegas Bay (LX) of Lake Mead. To investigate the potential for contaminants in LW influent to produce effects indicative of endocrine disruption in vivo, adult male and female common carp (Cyprinus carpio) were exposed in cages for 42-48 d at four sites in Lake Mead: LW, LX, and two reference locations in the lake. End points examined included gonadosomatic index; gonad histology; concentrations of plasma vitellogenin (VTG) and plasma sex steroids (17beta-estradiol (E2), testosterone (T), 11-ketotestosterone (11-KT)); plasma estrogen:androgen ratios (E2:T, E2:11-KT), in vitro production of T by gonad tissue, and hepatopancreas ethoxyresorufin O-deethylase activity. Few differences among fish caged at different sites were potentially attributable to exposure to contaminants PMID:15597896

  11. Log ASCII Standard (LAS) Files for Geophysical (Gamma Ray) Wireline Well Logs and Their Application to Geologic Cross Section C-C' Through the Central Appalachian Basin

    USGS Publications Warehouse

    Trippi, Michael H.; Crangle, Robert D., Jr.

    2009-01-01

    U.S. Geological Survey (USGS) regional geologic cross section C-C' (Ryder and others, 2008) displays key stratigraphic intervals in the central Appalachian basin. For this cross section, strata were correlated by using descriptions of well cuttings and gamma ray well log traces. This report summarizes the procedures used to convert gamma ray curves on paper well logs to the digital Log ASCII (American Standard Code for Information Interchange) Standard (LAS) format using the third-party software application Neuralog. The procedures could be used with other geophysical wireline logs also. The creation of digital LAS files from paper well logs by using Neuralog is very helpful, especially when dealing with older logs with limited or nonexistent digital data. The LAS files from the gamma ray logs of 11 wells used to construct cross section C-C' are included in this report. They may be downloaded from the index page as a single ZIP file.

  12. Changes in air quality at near-roadway schools after a major freeway expansion in Las Vegas, Nevada.

    PubMed

    Brown, Steven G; McCarthy, Michael C; DeWinter, Jennifer L; Vaughn, David L; Roberts, Paul T

    2014-09-01

    Near-roadway ambient black carbon (BC) and carbon monoxide (CO) concentrations were measured at two schools adjacent to a freeway and at an urban background school 2 km from the freeway to determine the change in concentrations attributable to vehicle emissions after the three-lane expansion of U.S. Highway 95 (US 95) in Las Vegas, Nevada. Between summer 2007 and summer 2008, average weekday small-vehicle volume increased by 40% +/- 2% (standard error). Average weekday large-vehicle volume decreased by 17% +/- 5%, due to a downturn in the economy and an associated decline in goods movement. Average vehicle speed increased from 58 to 69 mph, a 16% +/- 1% increase. The authors compared BC and CO concentrations in summer 2007 with those in summer 2008 to understand what effect the expansion of the freeway may have had on ambient concentrations: BC and CO were measured 17 m north of the freeway sound wall, CO was measured 20 m south of the sound wall, and BC was measured at an urban background site 2 km south of the freeway. Between summer 2007 and summer 2008, median BC decreased at the near-road site by 40% +/- 2% and also decreased at the urban background site by 24% +/- 4%, suggesting that much of the change was due to decreases in emissions throughout Las Vegas, rather than only on US 95. CO concentrations decreased by 14% +/- 2% and 10% +/- 3% at the two near-road sites. The decrease in BC concentrations after the expansion is likely due to the decrease in medium- and heavy-duty-vehicle traffic resulting from the economic recession. The decrease in CO concentrations may be a result of improved traffic flow, despite the increase in light-duty-vehicle traffic. Implications: Monitoring of BC and CO at near-road locations in Las Vegas demonstrated the impacts of changes in traffic volume and vehicle speed on near-road concentrations. However, urban-scale declines in concentrations were larger than near-road changes due to the impacts of the economic recession that

  13. Aerosol Light Absorption and Scattering at Four Sites in and Near Mexico City: Comparison with Las Vegas, Nevada, USA

    NASA Astrophysics Data System (ADS)

    Arnott, W. P.; Miranda, G. P.; Gaffney, J. S.; Marley, N. A.

    2007-05-01

    Four photoacoustic spectrometers (PAS) for aerosol light scattering and absorption measurements were deployed in and near Mexico City in March 2006 as part of the Megacity Impacts on Regional and Global Environments (MIRAGE). The four sites included: an urban site at Instituto Mexicano del Petroleo (Mexican Oil Institute, denoted by IMP); a suburban site at the Technological University of Tecamac; a rural site at "La Biznaga" ranch; and a site at the Paseo de Cortes (altitude 3,810 meters ASL) in the rural area above Amecameca in the State of Mexico, on the saddle between the volcanoes Popocatepetl and Iztaccihuatl. A similar campaign was held in Las Vegas, Nevada, USA in January-February, 2003. The IMP site gave in-situ characterization of the Mexico City plume under favorable wind conditions while the other sites provided characterization of the plume, mixed in with any local sources. The second and third sites are north of Mexico City, and the fourth site is south. The PAS used at IMP operates at 532 nm, and conveniently allowed for characterization of gaseous absorption at this wavelength as well. Instruments at the second and third sites operate at 870 nm, and the one at the fourth site at 780 nm. Light scattering measurements are accomplished within the PAS by the reciprocal nephelometery method. In the urban site the aerosol absorption coefficient typically varies between 20 and 180 Mm-1 during the course of the day and significant diurnal variation of the aerosol single scattering albedo was observed probably as a consequence of secondary aerosol formation. Comparisons with TSI nephelometer scattering at the T0 site will be presented. We will present the diurnal variation of the scattering and absorption as well as the single scattering albedo and fraction of absorption due to gases at the IMP site and compare with Las Vegas diurnal variation. Mexico City 'breaths' more during the course of the day than Las Vegas, Nevada in part because the latitude of

  14. Evolución en el tiempo de las relaciones Masa-Luminosidad y Corrección Bolométrica y Temperatura Efectiva contra Índice de Color

    NASA Astrophysics Data System (ADS)

    Miloni, L. A.; Camperi, J. A.

    Analizamos la evolución que en los últimos 70 años han tenido las relaciones M-L, BC vs CI y Teff vs CI. Se discuten las causas de esa evolución, se trata de incorporar los valores más modernos disponibles discutiendo su calidad y se deducen las relaciones que actualmente deberían ser las más confiables. Destacamos los puntos en los que estas relaciones continúan estando pobremente definidas y sería deseable mejorar en el futuro próximo.

  15. 2LAs, 3LAs, and the enterprise

    SciTech Connect

    Hoffmann, T.

    1998-01-01

    This article is about new things that engineers, facility managers and automation system operators need to learn about and understand when it comes to integrating information throughout an enterprise. The goal is to help one better understand the connection between building systems and building intelligence. The authors set the foundation with an overview of the latest concept in network communications, enterprise computing. Because any new technology spawns a number of acronyms, they`ll also investigate new two-, three-, four- and five-letter acronyms that directly affect the changing role of the building automation system (BAS) as it becomes an integral, contributing part of the business. In each case, one or more Internet URLs will be provided for more information.

  16. Cómo aumentar la actividad física de los niños durante el período del recreo en las escuelas

    PubMed Central

    Ludwig, David

    2014-01-01

    Objetivos. Analizamos si la participación de las escuelas en el Programa de Mejoramiento del Recreo (PMR) en la primavera del año 2011 estuvo asociada a tasas más altas de actividad física intensa en los niños. Métodos. En el PMR, un coordinador dirige a los niños para que practiquen juegos adecuados para la edad a fin de aumentar su nivel de actividad física. Durante el recreo en 25 escuelas primarias públicas de la ciudad de Nueva York (15 participantes en el PMR, 10 no participantes en el PMR) los investigadores observaron algunas áreas predeterminadas (n = 1 339 observaciones) y registraron el número de niños que estaban sedentarios, caminando o muy activos. Resultados. Tras el análisis estadístico con múltiples variables se encontró que la participación en el PMR era una variable predictiva significativa (P = 0,027) de la tasa de actividad física intensa (porcentaje de niños muy activos en las áreas de observación) cuyas medias de los mínimos cuadrados fueron de 41% en las escuelas participantes en el PMR y de 27% en escuelas no participantes en el PMR. En las escuelas participantes en el PMR se siguió registrando una tasa significativamente superior incluso cuando el coordinador de juegos no estaba en el área de observación, lo que sugiere un cambio en la cultura del recreo en las escuelas que participan en este programa. Conclusiones. La tasa de actividad física intensa en las escuelas participantes en el PMR fue 14 puntos porcentuales (o 52%) superior a la tasa registrada en las escuelas no participantes en el PMR. Esta intervención de bajo costo podría ser un agregado valioso a las herramientas para combatir la obesidad infantil y podría valer la pena reproducirla en otros sitios. PMID:24899455

  17. Mitigation of Disagreement in Peer Review among L2 Learners and Native Speakers in a College Writing Class (Mitigación del Impacto de las Opiniones de Desacuerdo en el Proceso de Revisión por Pares entre Estudiantes de una Segunda Lengua y Hablantes Nativos en una Clase de Escritura a Nivel Universitario)

    ERIC Educational Resources Information Center

    Christoffersen, Katherine O'Donnell

    2015-01-01

    Peer review is now a commonplace practice in process-oriented writing instruction. A crucial aspect of peer review is assessing another classmate's work, which encompasses the act of disagreement. Given its prevalence in the classroom, it is necessary to analyze how L2 learners mitigate disagreement in the context of peer review with other L2…

  18. For a Child, Life is a Creative Adventure: Supporting Development and Learning through Art, Music, Movement, and Dialogue. A Guide for Parents and Professionals. = Para los ninos, la vida es una aventura creativa: Como estimular el desarrollo y el aprendizaje por medio de las artes visuales, la musica, el movimiento y el dialogo. Guia para padres de familia y profesionales.

    ERIC Educational Resources Information Center

    Cohen, Elena

    Recognizing that creativity facilitates children's learning and development, the Head Start Program Performance Standards require Head Start programs to include opportunities for creative self-expression. This guide with accompanying videotape, both in English- and Spanish- language versions, encourages and assists adults to support children's…

  19. Repeated debris avalanches on Tenerife and genesis of Las Cañadas caldera wall (Canary Islands)

    NASA Astrophysics Data System (ADS)

    Cantagrel, Jean M.; Arnaud, Nicolas O.; Ancochea, Eumenio; Fúster, José M.; Huertas, María J.

    1999-08-01

    Geologic evidence on Tenerife, Canary Islands, indicates six successive north-directed debris avalanche events, including: the Anaga and Teno (ca. 6 Ma) events that affected the old basaltic series, and the Tigaiga (>2.3 Ma), Roques de García (possibly 0.6 0.7 Ma), Orotava (ca. 0.6 Ma), and Icod (<0.15 Ma) avalanche events that affected the Cañadas and Dorsal volcanic edifices. The approximate total volume (>1000 km3) inferred for these events can account for the volume of previous estimates of offshore volcanic debris. These repeated flank failures can also account for the present morphology of Las Cañadas caldera wall, which partly bounds a multiepisodic lateral-collapse structure 25 km wide.

  20. Heavy Metal Contamination and Salt Efflorescence Associated With Decorative Landscaping Rocks, Las Vegas, Nevada: The Need for Regulations

    NASA Astrophysics Data System (ADS)

    Mrozek, S. A.; Buck, B. J.; Brock, A. L.

    2004-12-01

    Las Vegas, Nevada is one of the fastest growing cities in the United States. Faced with water restrictions, decorative rock xeroscaping has become a very popular form of landscaping. Currently, there are no regulations controlling the geochemistry of the decorative rocks that can be used for these purposes. In this study, we examined three sites containing two different decorative rock products. The landscaping rocks, underlying soil, and surface salt crusts were analyzed to determine their mineralogy and chemistry. Methods of analysis include scanning electron microscopy (SEM), energy dispersive X-ray spectrometry (EDS), X-ray diffraction (XRD), inductively coupled plasma atomic emission spectroscopy (ICP), thin section analysis, and laser particle size analysis (LPSA). Preliminary results indicate the presence of halite (NaCl), bloedite (Na2Mg(SO4)2 4H2O), a hydrated magnesium sulfate, and possibly copper sulfate and copper chloride mineral phases in the surface salt crusts. Both copper minerals are regarded as hazardous substances by the Occupational Safety and Health Administration (OSHA) and the Environmental Protection Agency (EPA); these agencies have established minimum exposure limits for human contact with these substances. Copper sulfate and copper chloride are not naturally occurring minerals in the soils of the Las Vegas Valley, and analyses indicate that their formation may be attributed to the mineralogy of the decorative landscaping rocks. Further testing is needed to characterize this potential health hazard; however the preliminary results of this study demonstrate the need for regulations controlling the geochemistry of decorative rocks used for urban landscaping.

  1. An Intensity-Modulated CW LAS System for Application to ASCENDS: Overview of Development, Testing, and Evaluation

    NASA Astrophysics Data System (ADS)

    Ismail, S.; Harrison, F. W.; Dobler, J. T.; Browell, E. V.; Nehrir, A. R.; Lin, B.; Meadows, B.; Vanek, M. D.; Kooi, S. A.; Collins, J. E.; Refaat, T. F.; Yang, M. M.; Choi, Y.; DiJoseph, M.

    2012-12-01

    As part of the development of a capability for the NASA Active Sensing of CO2 Emissions over Nights, Days, and Seasons (ASCENDS) mission NASA Langley Langley Research Center (LaRC) and ITT EXELIS are collaborating to develop and demonstrate an approach for measuring column CO2 from space. A Multi-Functional Fiber Laser Lidar (MFLL), a laser absorption spectrometer (LAS) system has been used to demonstrate high precision column CO2 measurements from aircraft platforms. MFLL operates near the 1.57 micron region using an intensity modulated CW LAS system. High precision column CO2 measurements have been demonstrated over several land and ocean surfaces under a variety of atmospheric conditions, and also demonstrated insensitivity to variations in surface reflectivity and altitude. Encoded modulation schemes have been used to minimize the influence of thin clouds on column CO2 measurements. We present examples of these measurements from past flight campaigns, and developments are presented on models to predict the precision and accuracy of these measurements as determined from ground-based range testing at LaRC during July-August 2012. We present a summary of results from testing of the MFLL from the ground using various targets at a distance of 860 m. During these tests measurements are made using well characterized ground targets, controlled background conditions, and a variety of intermediate range, partially reflecting and light attenuating targets that are used as simulants for thin clouds. A variety of modulation schemes are being tested to discriminate against cloud interferences and for evaluating precise ranging capability. Profiles of CO2, relative humidity (RH), pressure, and temperature along the range are being made to validate the CO2 column measurements. These ground-based measurements are valuable to validate models for predicting the precision and accuracy of these measurements, interpretation of measurements from aircraft by the MFLL, and projecting

  2. A preliminary assessment of earthquake ground shaking hazard at Yucca Mountain, Nevada and implications to the Las Vegas region

    SciTech Connect

    Wong, I.G.; Green, R.K.; Sun, J.I.; Pezzopane, S.K.; Abrahamson, N.A.; Quittmeyer, R.C.

    1996-12-31

    As part of early design studies for the potential Yucca Mountain nuclear waste repository, the authors have performed a preliminary probabilistic seismic hazard analysis of ground shaking. A total of 88 Quaternary faults within 100 km of the site were considered in the hazard analysis. They were characterized in terms of their probability o being seismogenic, and their geometry, maximum earthquake magnitude, recurrence model, and slip rate. Individual faults were characterized by maximum earthquakes that ranged from moment magnitude (M{sub w}) 5.1 to 7.6. Fault slip rates ranged from a very low 0.00001 mm/yr to as much as 4 mm/yr. An areal source zone representing background earthquakes up to M{sub w} 6 1/4 = 1/4 was also included in the analysis. Recurrence for these background events was based on the 1904--1994 historical record, which contains events up to M{sub w} 5.6. Based on this analysis, the peak horizontal rock accelerations are 0.16, 0.21, 0.28, and 0.50 g for return periods of 500, 1,000, 2,000, and 10,000 years, respectively. In general, the dominant contributor to the ground shaking hazard at Yucca Mountain are background earthquakes because of the low slip rates of the Basin and Range faults. A significant effect on the probabilistic ground motions is due to the inclusion of a new attenuation relation developed specifically for earthquakes in extensional tectonic regimes. This relation gives significantly lower peak accelerations than five other predominantly California-based relations used in the analysis, possibly due to the lower stress drops of extensional earthquakes compared to California events. Because Las Vegas is located within the same tectonic regime as Yucca Mountain, the seismic sources and path and site factors affecting the seismic hazard at Yucca Mountain also have implications to Las Vegas. These implications are discussed in this paper.

  3. Identification of Pseudolysin (lasB) as an Aciduric Gluten-Degrading Enzyme with High Therapeutic Potential for Celiac Disease

    PubMed Central

    Wei, Guoxian; Tian, Na; Valery, Adriana C.; Zhong, Yi; Schuppan, Detlef; Helmerhorst, Eva J.

    2015-01-01

    OBJECTIVES Immunogenic gluten proteins implicated in celiac disease (CD) largely resist degradation by human digestive enzymes. Here we pursued the isolation of gluten-degrading organisms from human feces, aiming at bacteria that would digest gluten under acidic conditions, as prevails in the stomach. METHODS Bacteria with gluten-degrading activities were isolated using selective gluten agar plates at pH 4.0 and 7.0. Proteins in concentrated bacterial cell sonicates were separated by diethylaminoethanol chromatography. Enzyme activity was monitored with chromogenic substrates and gliadin zymography. Elimination of major immunogenic gluten epitopes was studied with R5 and G12 enzyme-linked immunosorbent assays. RESULTS Gliadin-degrading enzyme activities were observed for 43 fecal isolates, displaying activities in the ~150–200 and <50 kDa regions. The active strains were identified as Pseudomonas aeruginosa. Gliadin degradation in gel was observed from pH 2.0 to 7.0. Liquid chromatography–electrospray ionization–tandem mass spectrometry analysis identified the enzyme as pseudolysin (lasB), a metalloprotease belonging to the thermolysin (M4) family proteases. Its electrophoretic mobility in SDS–polyacrylamide gel electrophoresis and gliadin zymogram gels was similar to that of a commercial lasB preparation, with tendency of oligomerization. Pseudolysin eliminated epitopes recognized by the R5 antibody, while those detected by the G12 antibody remained intact, despite destruction of the nearby major T-cell epitope QPQLPY. CONCLUSIONS Pseudolysin was identified as an enzyme cleaving gluten effectively at extremely low as well as near-neutral pH values. The potential to degrade gluten during gastric transport opens possibilities for its application as a novel therapeutic agent for the treatment of CD. PMID:25895519

  4. Espectroscopía de Microondas en Jets Supersónicos

    NASA Astrophysics Data System (ADS)

    Alonso, J. L.; López, J. C.; Lesarri, A.; Blanco, S.; Sanz, M. E.; Mata, S.; Cocinero, J. E.; Sánchez, R.

    Complejos con Enlace de Hidrógeno. El entorno de bajas temperaturas de una expansión supersónica es un excelente laboratorio para estudiar el comportamiento conformacional de los complejos con enlace de hidrógeno. Nuestro grupo ha observado por vez primera enlaces de hidrógeno axial y ecuatorial en los complejos de tetrahidropirano, sulfuro de pentametileno y sulfuro de trimetileno con HCl y HF [1-6] generados en las expansiones adiabáticas en He, Ne o Ar y caracterizados por espectroscopía de microondas con transformadas de Fouier. Existe controversia a la hora de considerar a las interacciones C-H\\cdotsO como enlaces de hidrógeno o como simples interacciones de van der Waals. Las interacciones C-H\\cdotsO han sido estudiadas en el dímero del dimetil eter generado en la expansión supersónica y caracterizado por espectroscopía de microondas [7]. Estas interacciones se han analizado en los complejos formados entre los alcanos sustituidos del trifluorometano y difluorometano con oxirano [8] caracterizándose la existencia de interacciones C-F\\cdotsH-C que contribuyen a la estabilización de estos complejos. Ablación Láser: Estructura de Aminoácidos. Los aminoácidos poseen puntos de fusión elevados (>200oC) y se presentan en fases condensadas como formas dipolares (+H3N-CH(R)-COO-) distintas de las neutras de las cadenas polipéptidas. Con el fin de obtener la estructura de estas formas neutras es necesario experimentar en fase gas, en un entorno libre de interacciones como el de una expansión supersónica. Para solventar el problema de su baja presión de vapor, se ha diseñado un nuevo instrumento que combina la espectroscopía de microondas en jet supersónicos con técnicas de ablación láser [9] que evita los métodos de vaporización por calentamiento que conducen a la descomposición de los aminoácidos. Diversos confórmeros de los aminoácidos naturales de la prolina [10], valina [11], cis- y trans- hidroxiprolina, serina, cisteina, ldots

  5. Long-term continuous measurement of near-road air pollution in Las Vegas: Seasonal variability in traffic emissions impact on local air quality

    EPA Science Inventory

    Excess air pollution along roadways is an issue of public health concern and motivated a long-term measurement effort established by the U.S. Environmental Protection Agency in Las Vegas, Nevada. Measurements of air pollutants – including black carbon (BC), carbon monoxide (CO),...

  6. School Resegregation in the Mississippi of the West: Community Counternarratives on the Return to Neighborhood Schools in Las Vegas, 1968-1994

    ERIC Educational Resources Information Center

    Horsford, Sonya Douglass; Sampson, Carrie; Forletta, Felicia

    2013-01-01

    Background: School desegregation and resegregation in the Mountain West remain understudied despite the substantial impact the region's growth and demographic change have had on racial balance and diversity in schools. Home to the largest school district in the Mountain West and fifth largest school district in the country, Las Vegas's…

  7. Six month progress report on the Waste Package Project at the University of Nevada, Las Vegas, July 1991--January 1992: Management, quality assurance and overview

    SciTech Connect

    Ladkany, S.G.

    1991-12-31

    The progress of the waste package project at the University of Nevada, Las Vegas was the subject of this report. It covered aspects of management and quality assurance, container design, application of ASME Pressure Vessel Codes, structural analysis of containers, design of rock tunnels for storage, and heat transfer phenomena. (MB)

  8. Six month progress report on the Waste Package Project at the University of Nevada, Las Vegas, July 1991--January 1992: Management, quality assurance and overview

    SciTech Connect

    Ladkany, S.G.

    1991-01-01

    The progress of the waste package project at the University of Nevada, Las Vegas was the subject of this report. It covered aspects of management and quality assurance, container design, application of ASME Pressure Vessel Codes, structural analysis of containers, design of rock tunnels for storage, and heat transfer phenomena. (MB)

  9. NCI adopta el sendero científico para lograr las metas de la Misión contra el Cáncer

    Cancer.gov

    El director interino del NCI, doctor Douglas Lowy, aceptó hoy las recomendaciones de un Panel Listón Azul para 10 planteamientos científicos que en cinco años lograrán un progreso contra el cáncer equivalente a una década de trabajo.

  10. Summary of chemical data from onsite and laboratory analyses of groundwater samples from the surficial aquifer, Las Vegas, Nevada, April and August 1993 and September 1994

    USGS Publications Warehouse

    Reddy, Michael M.; Gunther, Charmaine D.

    2012-01-01

    Samples were collected from groundwater wells in and about the city of Las Vegas, Nevada, and were analyzed for selected major, minor and trace constituents. Analyses of blank and reference samples are summarized as mean and standard deviation values for all positive results.

  11. PROCEEDINGS OF THE NATIONAL GROUND WATER QUALITY SYMPOSIUM (3RD) HELD IN LAS VEGAS, NEVADA ON SEPTEMBER 15-17, 1976

    EPA Science Inventory

    The Third National Ground Water Quality Symposium was held in Las Vegas, September 15-17, 1976, in conjunction with the annual convention of the National Water Well Association. There were eight main sessions encompassing twenty-four technical papers. These were concerned with th...

  12. Reproductive Responses of Common Carp Cyprinus carpio in Cages to Influent of the Las Vegas Wash in Lake Mead, Nevada, from late Winter to early Spring

    EPA Science Inventory

    To investigate the potential for contaminants in Las Vegas Wash (LW) influent to produce effects indicative of endocrine disruption in vivo, adult male and female common carp were exposed in cages for 42-48 d at four sites and two reference locations in Lake Mead.

  13. Explorations of Colleges, Universities, and Career Training Centers in Las Vegas, Nevada: Creating Educational and Training Programs for Displaced Workers to Learn Marketable Employment Skills

    ERIC Educational Resources Information Center

    Gonyea, Jacob Patrick

    2012-01-01

    The city of Las Vegas, Nevada has experienced a slowdown in tourism, a drop in property taxes and consolidated tax revenue used to support the city's operating budget, and a lack of economic diversification. Because of these changes, the ability of displaced workers to learn marketable employment skills continues to be an important issue for…

  14. Institutional trust, information, and risk perceptions; Report of findings of the Las Vegas metropolitan area survey, June 29--July 1, 1992

    SciTech Connect

    Mushkatel, A.H.; Pijawka, K.D.

    1992-09-01

    This study reports on the preliminary results of a survey of attitudes and perceptions of Las Vegas area residents regarding the proposed high-level nuclear waste repository. The survey`s focus was to examine the various dimensions of trust and confidence in government`s efforts to develop the country`s nuclear waste repository in Yucca Mountain, Nevada.

  15. Exploring the effects of population growth on future land use change in the Las Vegas Wash watershed: an integrated approach of geospatial modeling and analytics

    EPA Science Inventory

    The Las Vegas Valley metropolitan area is one of the fastest growing areas in the southwestern United States. The rapid urbanization has led to many environmental problems. For instance, as population growth and urbanization continue, there will be a problem with water shortage. ...

  16. Full House: The Las Vegas building boom has stretched the creativity and resources of the fastest-growing school district in the nation. Edutopia, September/October 2004

    ERIC Educational Resources Information Center

    Furger, Roberta

    2004-01-01

    This once sleepy community, founded by Mormon missionaries in 1855 and jumpstarted by gambling 85 years later, now gobbles up real estate faster than a conventioneer chowing down at a midnight buffet. Every day of the week, two acres of Las Vegas area land are developed for commercial or residential use in a frenetic drive to accommodate the…

  17. A McOndo Writer's Take on Literature in the Era of Audiovisual and Digital Communication: The Case of Alberto Fuguet's "Las Peliculas de mi vida"

    ERIC Educational Resources Information Center

    Maier, Linda S.

    2011-01-01

    Alberto Fuguet, one of the leaders of the McOndo writers who seek cultural direction from the United States and exploit mass-media formulas, is a polarizing figure in contemporary Latin American culture. His most recent full-length novel, the semi-autobiographical "Las peliculas de mi vida" (2003), has led many to conclude that Fuguet is simply a…

  18. The Birth of a New Vocational-Technical Center. National Vocational-Technical Facility Planning Conference (Las Vegas, Nevada, May, 1967).

    ERIC Educational Resources Information Center

    Farnsworth, Clayton

    The principal of the Southern Nevada Vocational-Technical Center at Las Vegas, Nevada, briefly outlines its development and function. The facility cost approximately 3 million dollars and was built on 390 acres of land purchased from the Federal government. The PERT method was used in planning. Instructional facilities, including those for auto…

  19. Integrating NASA's Land Analysis System (LAS) image processing software with an appropriate Geographic Information System (GIS): A review of candidates in the public domain

    NASA Technical Reports Server (NTRS)

    Rochon, Gilbert L.

    1989-01-01

    A user requirements analysis (URA) was undertaken to determine and appropriate public domain Geographic Information System (GIS) software package for potential integration with NASA's LAS (Land Analysis System) 5.0 image processing system. The necessity for a public domain system was underscored due to the perceived need for source code access and flexibility in tailoring the GIS system to the needs of a heterogenous group of end-users, and to specific constraints imposed by LAS and its user interface, Transportable Applications Executive (TAE). Subsequently, a review was conducted of a variety of public domain GIS candidates, including GRASS 3.0, MOSS, IEMIS, and two university-based packages, IDRISI and KBGIS. The review method was a modified version of the GIS evaluation process, development by the Federal Interagency Coordinating Committee on Digital Cartography. One IEMIS-derivative product, the ALBE (AirLand Battlefield Environment) GIS, emerged as the most promising candidate for integration with LAS. IEMIS (Integrated Emergency Management Information System) was developed by the Federal Emergency Management Agency (FEMA). ALBE GIS is currently under development at the Pacific Northwest Laboratory under contract with the U.S. Army Corps of Engineers' Engineering Topographic Laboratory (ETL). Accordingly, recommendations are offered with respect to a potential LAS/ALBE GIS linkage and with respect to further system enhancements, including coordination with the development of the Spatial Analysis and Modeling System (SAMS) GIS in Goddard's IDM (Intelligent Data Management) developments in Goddard's National Space Science Data Center.

  20. NCI adopta el sendero científico para lograr las metas de la Misión Nacional contra el Cáncer

    Cancer.gov

    El director interino del NCI, doctor Douglas Lowy, aceptó hoy las recomendaciones de un Panel Listón Azul para 10 planteamientos científicos que en cinco años lograrán un progreso contra el cáncer equivalente a una década de trabajo.

  1. Astronomy in High School: Using a Mini-Planetarium to Understand Details of the Apparent Movement of Stars. (Spanish Title: Astronomía en la Escuela Secundaria: Comprendiendo los Detalles del Movimiento Aparente de Las Estrellas con un Miniplanetario.) Astronomia no Ensino Médio: Compreendendo Detalhes do Movimento Aparente das Estrelas com um Miniplanetário

    NASA Astrophysics Data System (ADS)

    dos Santos Leão, Demetrius

    2013-07-01

    The aim of this article is to present part of the results obtained by the intervention made from the author's Master degree project, which consisted in the development of a set of Astronomy classes for first year of High School students from a private school in the "Distrito Federal", Brasilia, Brazil, making use of a didactical material called mini-planetarium (MP) as the main resource. Using Paulo Freire's contextualization and dialogicity ideas as a theoretical framework guided by these lessons, it was proposed to the students the assembly and application of that resource in a planetarium session. During the project, some subjects such as the apparent trajectory of stars through Brasilia's sky, the location of the cardinal points beginning from the Southern Cross constellation, the color of stars and the stars being seen from a particular place were emphasized. It was found that the students showed an improvement of their understanding about these subjects, as well as a significant excitement with the developed methodology. El objetivo de este trabajo es presentar algunos de los resultados obtenidos en el proyecto de la tesis de maestría del autor, que incluyó el desarrollo de algunas clases de Astronomía, con estudiantes del primer año del bachillerato de una escuela privada del Distrito Federal (Brasilia, Brasil), utilizando como materia prima didáctica el recurso llamado miniplanetario (MP). Utilizando como base teórica orientadora de esas clases las ideas de contextualización y dialógica de Paulo Freire, fue propuesto a los estudiantes el montaje y la utilización de este recurso en una función de planetario. Durante el proyecto, se enfatizaron asuntos tales como la trayectoria aparente de las estrellas del cielo de Brasilia, la ubicación de los puntos cardinales a partir de la constelación de la Cruz del Sur, los colores de las estrellas y las estrellas vistas desde una localidad determinada. Se constató que los estudiantes mostraron una mejora

  2. [Ag20 {S2 P(OR)2 }12 ]: A Superatom Complex with a Chiral Metallic Core and High Potential for Isomerism.

    PubMed

    Dhayal, Rajendra S; Lin, Yan-Ru; Liao, Jian-Hong; Chen, Yuan-Jang; Liu, Yu-Chiao; Chiang, Ming-Hsi; Kahlal, Samia; Saillard, Jean-Yves; Liu, C W

    2016-07-11

    The synthesis and structural determination of a silver nanocluster [Ag20 {S2 P(OiPr)2 }12 ] (2), which contains an intrinsic chiral metallic core, is produced by reduction of one silver ion from the eight-electron superatom complex [Ag21 {S2 P(OiPr)2 }12 ](PF6 ) (1) by borohydrides. Single-crystal X-ray analysis displays an Ag20 core of pseudo C3 symmetry comprising a silver-centered Ag13 icosahedron capped by seven silver atoms. Its n-propyl derivative, [Ag20 {S2 P(OnPr)2 }12 ] (3), can also be prepared by the treatment of silver(I) salts and dithiophosphates in a stoichiometric ratio in the presence of excess amount of [BH4 ](-) . Crystal structure analyses reveal that the capping silver-atom positions relative to their icosahedral core are distinctly different in 2 and 3 and generate isomeric, chiral Ag20 cores. Both Ag20 clusters display an emission maximum in the near IR region. DFT calculations are consistent with a description within the superatom model of an 8-electron [Ag13 ](5+) core protected by a [Ag7 {S2 P(OR)2 }12 ](5-) external shell. Two additional structural variations are predicted by DFT, showing the potential for isomerism in such [Ag20 {S2 P(OR)2 }12 ] species. PMID:27189869

  3. A survey of homopteran species (Auchenorrhyncha) from coffee shrubs and poró and laurel trees in shaded coffee plantations, in Turrialba, Costa Rica.

    PubMed

    Rojas, L; Godoy, C; Hanson, P; Hilje, L

    2001-01-01

    A survey of homopteran species (Auchenorryncha) was conducted in coffee plantations with no shade (C), and in those with shade of either poró (Erythrina poeppigiana) (CP) or poró plus laurel (Cordia alliodora) (CPL), in Turrialba, Costa Rica. A total of 130 species in ten families were collected, dominated by Cicadellidae (82 species). Species richness was highest in the CP system (88), followed by CPL (74) and C systems (60). Five most common species for all systems were Fusigonalia lativittata, Hebralebra nicaraguensis, Neocoelidia sp., Oliarus sp. and Clastoptera sp. Diversification of the coffee agroecosystem favors some species while limiting others, and have no effect on the majority of species. Thus, only F. lativittata, Neocoelidia sp. and Scaphytopius ca. latidens were well represented in all systems, but were more abundant in coffee shrubs. Additionally, the following were the dominant species in each system: Graphocephala sp. 1 (C), F. lativittata (CP) and H. nicaraguensis (CPL). Four species abundant on laurel trees, including H. nicaraguensis, appeared almost exclusively on these tree species. Species similarity was highest on the CP and CPL systems (51% of the species in common), followed by the C and CP (39%) and the C and CPL systems (38%). These findings show that even disturbed systems can harbor many insect species, so that they deserve attention from conservation advocates and biologists. PMID:12189787

  4. Volcán Las Navajas, a Pliocene-Pleistocene trachyte/peralkaline rhyolite volcano in the northwestern Mexican volcanic belt

    NASA Astrophysics Data System (ADS)

    Nelson, Stephen A.; Hegre, Joann

    1990-01-01

    Volcán Las Navajas, a Pliocene-Pleistocene volcano located in the northwestern portion of the Mexican volcanic belt, erupted lavas ranging in composition from alkali basalt through peralkaline rhyolite, and is the only volcano in mainland Mexico known to have erupted pantellerites. Las Navajas is located near the northwestern end of the Tepic-Zacoalco rift and covers a 200-m-thick pile of alkaline basaltic lavas, one of which has been dated at 4.3 Ma. The eruptive history of the volcano can be divided into three stages separated by episodes of caldera formation. During the first stage a broad shield volcano made up of alkali basalts, mugearites, benmoreites, trachytes, and peralkaline rhyolites was constructed. Eruption of a chemically zoned ash flow then caused collapse of the structure to form the first caldera. The second stage consisted of eruptions of glassy pantellerite lavas that partially filled the caldera and overflowed its walls. This stage ended about 200 000 years ago with the eruption of pumice falls and ash flows, which led to the collapse of the southern portion of the volcano to form the second caldera. During the third stage, two benmoreite cinder cones and a benmoreite lava flow were emplaced on the northwestern flank of the volcano. Finally, the calc-alkaline volcano Sanganguey was built on the southern flank of Las Lavajas. Alkaline volcanism continued in the area with eruptions of alkali basalt from cinder cones located along NW-trending fractures through the area. Although other mildly peralkaline rhyolites are found in the rift zones of western Mexico, only Las Navajas produced pantellerites. Greater volumes of basic alkaline magma have erupted in the Las Navajas region than in the other areas of peralkaline volcanism in Mexico, a factor which may be necessary to provide the initial volume of material and heat to drive the differentiation process to such extreme peralkaline compositions.

  5. Enhancement of archaeological heritage. El Risco de las Cuevas at Perales de Tajuña, Madrid (Spain)

    NASA Astrophysics Data System (ADS)

    Freire-Lista, David Martin; Alvarez de Buergo, Mónica; Fort, Rafael

    2016-04-01

    Heritage conservation has a great impact on the economy of a country. The enhancement of archaeological sites is an investment that promotes tourism and culture. The interdisciplinary knowledge of heritage should be the basis of its management. Preventive actions, non-destructive analytical techniques and monitoring for the conservation of these assets should be promoted. "El Risco de las Cuevas" is a highly decayed and nearly vertical gypsum escarpment which contains a series of dwellings excavated during the Chalcolithic and much more recent times. It is located at Perales de Tajuña, 40 km southeast of Madrid, Spain. This monument is approximately 70 metres high and 500 metres wide. It was listed as a cultural and monumental heritage site by the regional government of Madrid in 1998. The gypsum escarpment housing the dwellings forms part of a lower Miocene unit (Madrid Basin). Debris cones with a mixture of debris from the lower, medium and upper units are found at the bottom of the rockwall. The vulnerability of this monument to atmospheric agents has been studied using "in situ" monitoring techniques of humidity, temperature and rate of rockfalls. Drones have been used for aerial photography in the highest areas of the escarpment and have provided an information network of fractures likely to cause rockfall. Gypsum artificial accelerated ageing has been carried out in the laboratory, including freeze/thaw, wet/dry, thermal shock and dissolution tests. To determine the response of these accelerated ageing processes, density, micro-roughness, ultrasound velocities (Vp and Vs), air permeability and microscopy measurements were made before, during and after ageing tests. Geomorphological studies, rates of decay, material characteristics and durability tests indicate that the decay is controlled by the mineralogy, clay content and porosity of the gypsum rock, as well as microclimate, temperature changes and rock fractures. Rockfalls are particularly relevant in the

  6. The Las Chacras-Potrerillos batholith (Pampean Ranges, Argentina): structural evidences, emplacement and timing of the intrusion

    NASA Astrophysics Data System (ADS)

    Siegesmund, S.; Steenken, A.; López de Luchi, M. G.; Wemmer, K.; Hoffmann, A.; Mosch, S.

    Within the southern part of the Sierra Pampeanas (the Sierra de San Luis, Argentina), a series of extensive intrusive bodies are regarded to post-date the Famatinian cycle but were emplaced during the Achalian, a period of heterogeneous deformation along crustal scale fault zones. The largest of those is the Las Chacras-Potrerillos batholith that is situated at the northern end of the transpressive, sinistral Guzmán shear zone. This composite pluton exhibits three sub-domains that comprise two granitoid sub-units each: The southern Potrerillos stock (muscovite-bearing red granite and biotite-bearing red granite) and the central (biotite porphyritic granite and giant porphyritic granite) and northern domain (equigranular granite and porphyritic granite) of the Las Chacras stock. The crystallisation ages of the biotite porphyritic granite is around 381 Ma (U/Pb on zircons and Pb/Pb on sphene), while the host rock was already cooled below 350 °C at 420 Ma. Thermal modelling approaches favour a pulsed intrusion with a duration of 1.5 Ma. The emplacement was followed by rapid cooling below the muscovite cooling temperature. Biotite cooling ages in different sub-units reflect either a long-lasting cooling history of approximately 30 Ma (which is supported by the modelling) or a reheating effect at around 350 Ma. Devonian-age determinations on the fault rocks and granitoids point to a syn-tectonic emplacement of the batholith. The pluton is interpreted to be positioned at the crossover of sinistral shear zones. The origin of this NNE directed extensional setting in a transpressive regime seems to be related to the transfer of displacement along a secondary set of NNW-trending sinistral faults. The final emplacement is due to a subsequent ballooning of the batholith following the direction of space creation. This model is based on the relative timing of the emplacement sequence and macroscopically visible planar fabrics in the field as well as magnetic fabric data. Our

  7. Sedimentology and paleoenvironments of the Las Chacritas carbonate paleolake, Cañadón Asfalto Formation (Jurassic), Patagonia, Argentina

    NASA Astrophysics Data System (ADS)

    Cabaleri, Nora G.; Benavente, Cecilia A.

    2013-02-01

    The Las Chacritas Member is the lower part of the Cañadón Asfalto Formation (Jurassic). The unit is a completely continental limestone succession with volcanic contributions that were deposited during the development of the Cañadón Asfalto Rift Basin (Chubut province, Patagonia, Argentina). A detailed sedimentological analysis was performed in the Fossati depocenter to determine the paleoenvironments that developed in the context of this rift. The Las Chacritas Member represents a carbonate paleolake system with ramp-shaped margins associated with wetlands that were eventually affected by subaerial exposure and pedogenesis. This process is represented by three main subenvironments: a) a lacustrine setting sensu stricto (lacustrine limestone facies association), represented by Mudstones/Wackestones containing porifera spicules (F1), Intraclastic packstones (F6) and Tabular stromatolites (F10) in which deposition and diagenesis were entirely subaqueous; b) a palustrine setting (palustrine limestone facies association) containing Microbial Mudstones (F2), Intraclastic sandy packstone with ostracode remains (F3), Oncolitic packstone (F5), Brecciated limestone (F7) and Nodular-Mottled limestone (F8) representing shallow marginal areas affected by groundwater fluctuations and minor subaerial exposure; and c) a pedogenic paleoenvironment (pedogenic limestone facies association) including Intraclastic limestone (F4) and Packstones containing Microcodium (F9) facies displaying the major features of subaerial exposure, pedogenic diagenesis and the development of paleosols. The fluvial-palustrine-lacustrine succession shows a general shallow upward trend in which contraction-expansion cycles are represented (delimited by exposure and surface erosion). The variations in the successive formations reflect the responses to fluctuations in a combination of two major controls, the tectonic and local climatic variables. The predominance of the palustrine facies associations was

  8. Integrating Collaboration, Adaptive Management, and Scenario-Planning to Address Rapid Change: Experiences at Las Cienegas National Conservation Area

    NASA Astrophysics Data System (ADS)

    Caves, J. K.; Bodner, G.; Simms, K.; Fisher, L.; Robertson, T.

    2012-12-01

    There is growing recognition that public lands cannot be managed as islands; rather, land management must address the ecological, social, and temporal complexity that often spans jurisdictions and traditional planning horizons. Collaborative decision-making and adaptive management (CAM) have been promoted as methods to reconcile competing societal demands and respond to complex ecosystem dynamics. We present the experiences of land managers and stakeholders in using CAM at Las Cienegas National Conservation Area (LCNCA), a highly valued site under the jurisdiction of the Bureau of Land Management (BLM). The CAM process at Las Cienegas is marked by strong stakeholder engagement, with four core elements: 1) shared watershed goals with measurable resource objectives; 2) mechanisms to incorporate new information into decision-making; 3) efforts to make information increasingly relevant and reliable; and 4) shared learning to improve both the process and management actions. The combination of stakeholder engagement and adaptive management has led to agreement on contentious issues, more innovative solutions, and more effective land management. Yet the region is now experiencing rapid changes outside managers' control—including climate change, human population growth, and reduced federal budgets—with large but unpredictable impacts on natural resources. While CAM experience provides a strong foundation for making the difficult and contentious management decisions that such changes are likely to require, neither collaboration nor adaptive management provides a sufficient structure for addressing uncontrollable and unpredictable change. As a result, LCNCA is exploring two specific modifications to CAM that may better address emerging challenges, including: 1) Creating nested resource objectives to distinguish between those objectives which may be crucial from those which may hinder a flexible response to climate change, and 2) Incorporating scenario planning into CAM

  9. late Pleistocene and Holocene pollen record from Laguna de las Trancas, northern coastal Santa Cruz County, California

    USGS Publications Warehouse

    Adam, David P.; Byrne, Roger; Luther, Edgar

    1981-01-01

    A 2.1-m core from Laguna de las Trancas, a marsh atop a landslide in northern Santa Cruz County, California, has yielded a pollen record for the period between about 30,000 B. P. and roughly 5000 B. P. Three pollen zones are recognized. The earliest is characterized by high frequencies of pine pollen and is correlated with a mid-Wisconsinan interstade of the mid-continent. The middle zone contains high frequencies of both pine and fir (Abies, probably A. grandis) pollen and is correlated with the last full glacial interval (upper Wisconsinan). The upper zone is dominated by redwood (Sequoia) pollen and represents latest Pleistocene to middle Holocene. The past few thousand years are not represented in the core. The pollen evidence indicates that during the full glacial period the mean annual temperature at the site was about 2°C to 3°C lower than it is today. We attribute this small difference to the stabilizing effect of marine upwelling on the temperature regime in the immediate vicinity of the coast. Precipitation may have been about 20 percent higher as a result of longer winter wet seasons.

  10. Abundance Results from the Las Campanas Observatory and McDonald Observatory High-Resolution Metal-Poor Star Survey

    NASA Astrophysics Data System (ADS)

    Roederer, Ian U.; Preston, G.; Shectman, S.; Thompson, I.; Sneden, C.

    2011-01-01

    We have undertaken a survey to collect high-resolution and high S/N spectra for more than 300 metal-poor stars. The majority of our sample was selected from the HK Survey of Beers, Preston, and Shectman, and nearly all stars with estimated [Fe/H] < -2.5 have been observed with the MIKE spectrograph on the Magellan-Clay Telescope at Las Campanas Observatory. Additional metal-poor targets were selected based on their kinematic properties and observed with the Tull spectrograph on the Smith Telescope at McDonald Observatory. Previous abundance analyses based on high-resolution and high S/N spectra have been performed for only about 20% of the sample. While this sample naturally allows us to reconfirm and expand upon previously-detected low metallicity abundance trends and identify new stars with unique abundance signatures, its real power is the ability to probe chemical dispersion in abundance ratios. We exploit this attribute by performing line-by-line differential abundance analyses for many elements in large numbers of stars at a single metallicity and evolutionary state. This allows us to assess the evolution of the cosmic scatter of the chemistry of the ISM at very early times in the halo of the Galaxy. Generous funding has been provided by the U.S. National Science Foundation (grant AST 09-08978 to C.S.).

  11. Characterization and prediction of spatial variability of unsaturated hydraulic properties in a field soil: Las Cruces, New Mexico

    SciTech Connect

    Yeh, T.C.J.; Greenholtz, D.E.; Nash, M.S.; Wierenga, P.J.

    1991-12-31

    A 91-m transect was set up in an irrigated field near Las Cruces, New Mexico to investigate the spatial variability of unsaturated soil properties. A total of 455 sampling points were monitored along a grid consisting of 91 stations placed 1 m apart by 5 depths per station. Post-irrigation soil water tension and water content measurements were recorded over 45 days at 11 time periods. The instantaneous profile was used to estimate the unsaturated hydraulic conductivity at the 455 sampling points. Fifty soil samples were also taken for analyzing sand, silt, and clay content distributions. The spatial and temporal variability of soil water tension and water content were investigated along with the spatial variability of parameters of an unsaturated hydraulic conductivity model. Results of the analysis show that spatial variation in soil water tension and water content is consistent with the soil texture spatial variability. In addition, the spatial distribution of the estimated parameter value of unsaturated hydraulic conductivity reflects the soil texture distribution. Using the statistics of the estimated hydraulic parameter values, a stochastic soil water tension model was employed to reproduce the variability of observed soil water tension. Although many assumptions were made, the results of the simulation appear promising.

  12. Characterization and prediction of spatial variability of unsaturated hydraulic properties in a field soil: Las Cruces, New Mexico

    SciTech Connect

    Yeh, T.C.J.; Greenholtz, D.E. . Dept. of Hydrology and Water Resources); Nash, M.S. . Dept. of Crop and Soil Sciences); Wierenga, P.J. . Dept. of Soil and Water Science)

    1991-01-01

    A 91-m transect was set up in an irrigated field near Las Cruces, New Mexico to investigate the spatial variability of unsaturated soil properties. A total of 455 sampling points were monitored along a grid consisting of 91 stations placed 1 m apart by 5 depths per station. Post-irrigation soil water tension and water content measurements were recorded over 45 days at 11 time periods. The instantaneous profile was used to estimate the unsaturated hydraulic conductivity at the 455 sampling points. Fifty soil samples were also taken for analyzing sand, silt, and clay content distributions. The spatial and temporal variability of soil water tension and water content were investigated along with the spatial variability of parameters of an unsaturated hydraulic conductivity model. Results of the analysis show that spatial variation in soil water tension and water content is consistent with the soil texture spatial variability. In addition, the spatial distribution of the estimated parameter value of unsaturated hydraulic conductivity reflects the soil texture distribution. Using the statistics of the estimated hydraulic parameter values, a stochastic soil water tension model was employed to reproduce the variability of observed soil water tension. Although many assumptions were made, the results of the simulation appear promising.

  13. Selenium concentrations in water and plant tissues of a newly formed arid wetland in Las Vegas, Nevada.

    PubMed

    Pollard, James; Cizdziel, James; Stave, Krystyna; Reid, Michelle

    2007-12-01

    There is concern that elevated levels of selenium found in the source water of a newly formed wetland park in Las Vegas, Nevada, may have detrimental effects on local wildlife. In this study, we collected and analyzed water samples monthly for a three year period from the inflow and outflow of the system. We also gathered dominant aquatic plants and selected terrestrial plants and analyzed the water and plant tissues (root, shoot, leaf and flower) for selenium by high resolution Inductively Coupled Plasma Mass Spectrometer. Except for storm events and the introduction of an alternative low selenium content source water during summer low-flow conditions, selenium in the water was relatively stable. The concentration in the outflow tended to be slightly lower than the inflow. Concentrations of selenium in the dominant plant taxa in this wetlands were typical of ecosystems in the western United States and varied by taxa, tissue type, localized conditions (e.g., contact with selenium-laden water), and to a lesser extent, seasons. Selenium in the aquatic plant spiny naiad (Najas marina) was relatively high and may pose an ecological risk to wildlife during the late spring and summer. Additional work is underway investigating aquatic food chain accumulations of selenium as well as mass balance of selenium in the system. PMID:17394092

  14. Seismic activity and stress tensor inversion at Las Tres Vírgenes Volcanic and Geothermal Field (México)

    NASA Astrophysics Data System (ADS)

    Antayhua-Vera, Yanet; Lermo-Samaniego, Javier; Quintanar-Robles, Luis; Campos-Enríquez, Oscar

    2015-10-01

    We analyze local earthquakes occurring between 2003 and 2012 at the Las Tres Vírgenes Volcanic and Geothermal Field (TVVGF) to establish their temporal and spatial distribution, and relationships with local and regional fault systems, water injection, acid stimulation and steam production tests. We obtained focal mechanisms and inverted data for the stress tensor to understand the local and regional stress fields. We analyzed 423 local earthquakes with magnitudes between 0.1 and 2.9 Mc and hypocentral depths from 0.2 to 7.4 km b.s.l. The cutoff depth at ~ 7.4 km possibly delineates the brittle-ductile transition zone. We identified seven swarms (from 1 to 7). Swarms 1 (December 2009), 2 (May 2010), 3 (June-July 2010) and 7 (December 2012) are strongly correlated with injection processes; whereas swarms 5 (April 2012) and 6 (September 2012) are correlated with local tectonic faults. Stress inversion showed NW-SE, E-W and NE-SW extensional orientations (Shmin), in agreement with the local tectonic stress field; while NE-SW compressional orientations (SHmax) are correlated with the regional tectonic stress field.

  15. Can a Spanish science education journal become international? the case of Enseñanza de las Ciencias

    NASA Astrophysics Data System (ADS)

    Espinet, Mariona; Izquierdo, Mercè; Garcia-Pujol, Clara

    2015-12-01

    In this paper we discuss the case of the science education research journal Enseñanza de las Ciencias (EC) around the issue of its internationalization and the consequences this process has had and is still having on the use and preservation of different languages and more specifically the Castilian (Spanish) language. We first frame the concept of globalization and internationalization, and identify three important dimensions involved in the process of internationalization of EC such as language use, actors involved and resources available. Secondly, we address the historical evolution of EC along three phases of internationalization. In each phase we discuss the tensions experienced in relevant internationalization dimensions focusing particularly on the use of languages. We conclude by advocating a plurilingual and multicultural model for a science education research journal as an alternative to the hegemony of international English written journals. In doing so we want to continue the conversation on the role that local and national science education research journals have in promoting science education around the world.

  16. The Shadow of a Gnomon Along a Year: Routine Observations and Teaching of Apparent Motion of the Sun and the Four Seasons. (Spanish Title: La Sombra de un Gnomon lo Largo de un Año: Observaciones de Rutina y la Enseñanza del Movimiento Aparente del Sol y Las Cuatro Estaciones.) A Sombra de um Gnômon ao Longo de um Ano: Observações Rotineiras e o Ensino do Movimento Aparente do Sol E das Quatro Estações

    NASA Astrophysics Data System (ADS)

    Trogello, Anderson Giovani; Danhoni Neves, Marcos Cesar; de Carvalho Rutz da Silva, Sani

    2013-12-01

    Many misconceptions are recognized among the various groups of students, especially in the elementary school. Among them, the apparent motion of the Sun, in spite of its daily occurrence, is subject to varied interpretations. Thus, the observation and recording of the motion of the stars in the celestial vault is a necessary task for astronomy education. The work presented here proposes the presentation of the results of observations of the apparent movement of the sun by marking the shadow of a vertical gnomon by the students in a class of sixth graders of elementary rural school of Paraná. The project itself was conducted in four stages, on dates near the March equinox, the June solstice, the September equinox and the December solstice. In addition, lectures were developed in the classroom. Such methods sought to build concepts around the apparent movement of the Sun and the alternation of the seasons. Given the results of the activities, an evaluation was applied and the data demonstrated a desired student learning such as: the recognition of the cardinal points, the description of the apparent solar motion and the occurrence of the seasons and their alternation from astronomical observations at naked eye. Muchos conceptos aternativos son conocidos entre los distintos grupos de alumnos, sobre todo en la educación básica. Entre ellos, el movimiento aparente del Sol, por más cotidiano que sea, se presta a interpretaciones variadas. Por lo tanto, observar y registrar el movimiento de las estrellas en la bóveda celeste se torna una tarea necesaria para la educación en astronomía. El trabajo que aquí se presenta propone la presentación de los resultados de la observación del movimiento aparente del sol a través de la marcación de la sombra del gnomon vertical a cargo de los estudiantes en una división de sexto grado de de la escuela primaria rural de Paraná. El proyecto en sí se llevó a cabo en cuatro etapas, en fechas cercanas al equinoccio de marzo

  17. Geologic and geophysical maps of the Las Vegas 30' x 60' quadrangle, Clark and Nye counties, Nevada, and Inyo County, California

    USGS Publications Warehouse

    Page, William R.; Lundstrom, Scott C.; Harris, Anita G.; Langenheim, V.E.; Workman, Jeremiah B.; Mahan, Shannon; Paces, James B.; Dixon, Gary L.; Rowley, Peter D.; Burchfiel, B.C.; Bell, John W.; Smith, Eugene I.

    2005-01-01

    Las Vegas and Pahrump are two of the fastest growing cities in the US, and the shortage of water looms as among the greatest future problems for these cities. These new maps of the Las Vegas 30 x 60-minute quadrangle provide a geologic and geophysical framework and fundamental earth science database needed to address societal issues such as ground water supply and contamination, surface flood, landslide, and seismic hazards, and soil properties and their changing impact by and on urbanization. The mountain ranges surrounding Las Vegas and Pahrump consist of Mesozoic, Paleozoic and Proterozoic rocks. A majority of these rocks are Paleozoic carbonate rocks that are part of Nevada's carbonate rock aquifer province. The Spring Mountains represent a major recharge site in the province, where maximum altitude is 3,632 m (Charleston Peak) above sea level. Rocks in the Sheep and Las Vegas Ranges and Spring Mountains contain correlative, northeast-striking, southeast-verging thrust faults that are part of the Cretaceous, Sevier orogenic belt. These thrusts were offset during the Miocene by the Las Vegas Valley shear system (LVVSZ). We conducted new mapping in the Blue Diamond area, highlighting refined work on the Bird Spring thrust, newly studied ancient landslides, and gravity-slide blocks. We conducted new mapping in the Las Vegas Range and mapped previously unrecognized structures such as the Valley thrust and fold belt; recognition of these structures has led to a refined correlation of Mesozoic thrust faults across the LVVSZ. New contributions in the quadrangle also include a greatly refined stratigraphy of Paleozoic bedrock units based on conodont biostragraphy. We collected over 200 conodont samples in the quadrangle and established stratigraphic reference sections used to correlate units across the major Mesozoic thrust faults. Quaternary deposits cover about half of the map area and underlie most of the present urbanized area. Deposits consist of large coalescing

  18. American Recovery and Reinvestment Act (ARRA) FEMP Technical Assistance Federal Aviation Administration Project 209 - Control Tower and Support Building, Las Vegas, NV

    SciTech Connect

    Arends, J.; Sandusky, William F.

    2010-03-31

    This report represents findings of a design review team that evaluated construction documents (at the 70% level) and operating specifications for a new control tower and support building that will be built in Las Vegas, Nevada by the Federal Aviation Administration (FAA). The focus of the review was to identify measures that could be incorporated into the final design and operating specification that would result in additional energy savings for the FAA that would not have otherwise occurred.

  19. Synaptic membrane responses to acute and chronic alcohol intoxication in high alcohol sensitive (HAS) and low alcohol sensitive (LAS) selectively bred rats.

    PubMed

    Beaugé, F; Kerfriden, G; Ménez, J F; Aufrère, G; Le Bourhis, B

    1994-11-01

    HAS (high alcohol sensitive) and LAS (low alcohol sensitive) lines of rats have been selectively bred based on their differences in ethanol-induced sleep time. In the present study, the two lines were compared to examine another central effect of acute alcohol intoxication: namely, hypothermia. As the disturbances in membrane microorganization have been associated with the nervous system's sensitivity and tolerance to ethanol, the synaptic plasma membrane fluidity and acute sensitivity to ethanol were also evaluated by fluorescence polarization of DPH probes in the HAS and LAS rats. The two lines did not differ in the magnitude of their hypothermic response after acute injection of ethanol (3 g/kg body wt, i.p.). Although membranes in the HAS line were slightly more rigid than in the LAS line, the level of membrane disordering after acute ethanol addition was identical for the two lines in the region examined with the DPH probe. Following the chronic intoxication of the rats, the two lines developed tolerance to the hypnotic and hypothermic effects of ethanol. In the same way, a membrane resistance (i.e. tolerance) to the disordering effect of acute ethanol addition developed in the region probed with DPH. In general, the LAS line showed a more pronounced level of tolerance than the HAS line at both the functional and membrane level. These results suggest that different measures used to assess the depressant action of ethanol, such as sleep time, hypothermia or membrane disordering, may not be related and could indicate different genetic origins.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:7695793

  20. Ground-water conditions in Las Vegas Valley, Clark County, Nevada; Part 2, Hydrogeology and simulation of ground-water flow

    USGS Publications Warehouse

    Morgan, David S.; Dettinger, Michael D.

    1996-01-01

    In sedimentary deposits beneath arid Las Vegas Valley, ground-water levels have declined as much as 280 feet since 1912 in deeper aquifers due to pumping associated with urban development. Accompanying land subsidence has been as great as 5 feet. Predictive simulations show that by maintaining pumpage and recharge at 1980 levels and using municipal wells only during periods of peak water demand, rates of water-level decline and land subsidence will be reduced.

  1. Degradación de Marismas Costera: el Impacto de la Eutrofización en la Supervivencia del las Marismas Costeras en New England y Central California, USA. (Salt Marsh Deterioration in New England and Central California: Impacts of Eutrophication on Salt Marsh Survival.)

    EPA Science Inventory

    Las marismas costeras proporcionan numerosos beneficios a los ecosistemas, incluyendo la proporción del hábitat de la flora y fauna, la protección de las zonas costeras contra inundaciones durante eventos extremos, mejoran la calidad del agua para las almejas y ostras a través de...

  2. Hydrologic, water-quality, and biological assessment of Laguna de las Salinas, Ponce, Puerto Rico, January 2003-September 2004

    USGS Publications Warehouse

    Soler-López, Luis R.; Gómez-Gómez, Fernando; Rodríguez-Martínez, Jesús

    2005-01-01

    The Laguna de Las Salinas is a shallow, 35-hectare, hypersaline lagoon (depth less than 1 meter) in the municipio of Ponce, located on the southern coastal plain of Puerto Rico. Hydrologic, water-quality, and biological data in the lagoon were collected between January 2003 and September 2004 to establish baseline conditions. During the study period, rainfall was about 1,130 millimeters, with much of the rain recorded during three distinct intense events. The lagoon is connected to the sea by a shallow, narrow channel. Subtle tidal changes, combined with low rainfall and high evaporation rates, kept the lagoon at salinities above that of the sea throughout most of the study. Water-quality properties measured on-site (temperature, pH, dissolved oxygen, specific conductance, and Secchi disk transparency) exhibited temporal rather than spatial variations and distribution. Although all physical parameters were in compliance with current regulatory standards for Puerto Rico, hyperthermic and hypoxic conditions were recorded during isolated occasions. Nutrient concentrations were relatively low and in compliance with current regulatory standards (less than 5.0 and 1.0 milligrams per liter for total nitrogen and total phosphorus, respectively). The average total nitrogen concentration was 1.9 milligrams per liter and the average total phosphorus concentration was 0.4 milligram per liter. Total organic carbon concentrations ranged from 12.0 to 19.0 milligrams per liter. Chlorophyll a was the predominant form of photosynthetic pigment in the water. The average chlorophyll a concentration was 13.4 micrograms per liter. Chlorophyll b was detected (detection limits 0.10 microgram per liter) only twice during the study. About 90 percent of the primary productivity in the Laguna de Las Salinas was generated by periphyton such as algal mats and macrophytes such as seagrasses. Of the average net productivity of 13.6 grams of oxygen per cubic meter per day derived from the diel

  3. The high-grade Las Cruces copper deposit, Spain: a product of secondary enrichment in an evolving basin

    NASA Astrophysics Data System (ADS)

    Tornos, Fernando; Velasco, Francisco; Slack, John F.; Delgado, Antonio; Gomez-Miguelez, Nieves; Escobar, Juan Manuel; Gomez, Carmelo

    2016-04-01

    The Las Cruces deposit (Iberian Pyrite Belt) includes a large, high-grade cementation zone capped by unusual rocks that contain carbonates, galena, iron sulphides, and quartz. Between the Late Cretaceous(?) and Tortonian, the volcanogenic massive sulphides were exhumed and affected by subaerial oxidation that formed paired cementation and gossan zones. Onset of Alpine extension produced accelerated growth of the cementation zone along extensional faults, leading to formation of the high-grade copper ore at ca. 11 Ma. Later, replacement of the overlying gossan by sulphide- and carbonate-rich rocks beneath sealing marl sediments is thought to have involved microbial processes, occurring between the Messinian (ca. 7.2 Ma) and today. Isotope data show that the cementation zone formed by the mixing of descending acidic waters derived from oxidation of the massive sulphides, with upwelling geothermal waters flowing at temperatures above 100 °C. The C, O, and Sr isotope values of the mineralization (87Sr/86Sr 0.7101-0.7104) and of the local groundwater (0.7102-0.7104) reflect equilibration with basement rocks, and indicate that influence on the ore-forming process by marl-equilibrated water (0.7091-0.7093) or Miocene seawater (0.7086-0.7092) was negligible. The high sulphur isotope values of the sulphides in the biogenic zone (most +19 to +24 ‰) are well above those of the primary sulphides (δ34S ca. -6.8 to +10.3 ‰) and likely reflect formation of the biogenic sulphides by reduction of aqueous sulphate in the groundwaters. Sulphur isotope values of the cementation zone (δ34S ca. -2.4 to +21.7 ‰) are also consistent with some contribution of sulphur from the biogenic reduction of aqueous sulphate.

  4. Structural controls on karstic conduits in a collisional orogen (Sierra de las Nieves, Betic Cordillera, S Spain)

    NASA Astrophysics Data System (ADS)

    Pedrera, A.; Luque-Espinar, J. A.; Martos-Rosillo, S.; Pardo-Igúzquiza, E.; Durán-Valsero, J. J.; Martínez-Moreno, F.; Guardiola-Albert, C.

    2015-06-01

    We characterize the fracture pattern, including both meso-scale joints and macro-scale faults, within the central sector of Sierra de las Nieves (Betic Cordillera, S Spain), which contains one of the largest karstification systems in Europe. Structural data were compared with the direction pattern of the karstic conduit network of the largest caves. Carbonate rocks were deformed in a collisional setting and exposed at the surface since the early Miocene. Normal and normal-oblique faults trending NW-SE to WNW-ESE are the most prominent brittle structures, having formed coevally with shorter NE-SW normal to normal-dextral after the main thrusting phase. In addition, two main open joint sets striking NW-SE and NE-SW developed on a broad scale. Orthogonal normal faults and open joints suggest an extensional setting characterized by horizontal minimum (S3) and intermediate (S2) stress axes of similar magnitudes that intermittently shifted their positions during the middle-to-late Miocene. Vertical water flow coming from direct recharge sectors tends to infiltrate across these high-dipping faults, mainly concentrating at fault intersections, thus favoring sub-vertical conduit formation within the vadose zone. Horizontal paleo-phreatic levels are perched linked to the recent uplift undergone by the sector, giving us the opportunity to analyze the incidence of fractures at the phreatic zone. Joint sets determine the hydraulic anisotropy within the former phreatic levels. Because our study illustrates the primary role of diverse tectonic structures during massive multiphase cave development above and below the water table, it could contribute to better constraining of the models of karstic conduit formation.

  5. Computer graphics synthesis for inferring artist studio practice: an application to Diego Velázquez's Las Meninas[

    NASA Astrophysics Data System (ADS)

    Stork, David G.; Furuichi, Yasuo

    2009-02-01

    Diego Velázquez's Las meninas (1656) has been called by some art experts "the most important painting of the 17th century," "a theology of painting," and even "the world's greatest painting"; it has been the subject of intensive study. The work depicts a complex scene in the Alcázar palace of King Philip IV of Spain, and includes mirror reflections of the king and queen, apparently standing in place of the viewer, as well as the artist himself standing before an enormous canvas on an easel. Nevertheless, questions remain about the studio and the proper viewing configuration: Is the artist looking toward the perspectivally correct position of the viewer in the museum space (center of projection), outside the picture space? Does the perspectivally correct position correspond to the locations of the king and queen seen reflected in the mirror? Is the bright illumination on the king and queen (as revealed in the mirror) consistent with the lighting in the tableau itself? We addressed these questions in a new way: by building a full computer graphics model of the figures and tableau as well as the viewer's space outside the painting. In our full model, the painting itself is represented as a translucent window onto which the picture space is projected toward the center of projection, that is, the viewer. Our geometric and (new) lighting evidence confirm Janson's and Snyder's contention that the plane mirror on the back wall reflects the other side of the large painting depicted within the tableau, not the king and queen themselves in the studio. We believe our computer graphics synthesis of both the tableau within the painting and the viewer's space in the real world is the first of its kind to address such problems in the history of art.

  6. Palinspastic reconstruction of Lower Mesozoic stratigraphic sequences near the latitude of Las Vegas: Implications for the entire Great Basin

    SciTech Connect

    Marzolf, J.E. . Dept. of Geology)

    1993-04-01

    On the Colorado Plateau, lower Mesozoic stratigraphy is subdivided by regional unconformities into the Lower Triassic Moenkopi, Upper Triassic Chinle, Lower and Middle( ) Jurassic Glen Canyon, and Middle Jurassic lower San Rafael tectonosequences. Palinspastic reconstruction for Cenozoic extensional and mesozoic compressional deformations near the latitude of Las Vegas indicates the Moenkopi tectono-sequence constructed a passive-margin-like architecture of modest width overlapping folded. Thrust-faulted, and intruded Permian strata, with state boundaries fixed relative to the Colorado Plateau, comparison of the location of the Early Triassic shelf-slope break near latitude 36[degree] with the palinspastically restored location of the shelf-slope break in southeastern Idaho implies strata of the Moenkopi tectonosequence in the Mesozoic marine province of northwest NV lay in western utah in the Early Triassic. This reconstruction: suggests that the Galconda and Last Chance faults are part of the same thrust system; aligns late Carnian paleovalleys of the chinle tectonosequence on the Colorado Plateau with a coeval northwest-trending paleovalley cut across the Star Pea, and the Norian Cottonwood paleovalley with the coeval Grass Valley delta; defines a narrow, northward deepening back-arc basin in which the Glen Canyon tectonosequence was deposited; aligns east-facing half grabens along the back side of the arc from the Cowhole Mountains to the Clan Alpine Range; projects the volcan-arc/back-arc transition from northwest Arizona to the east side of the Idaho batholith; and predicts the abrupt facies change from silicic volcanics to marine strata of the lower San Rafael sequence lay in western Utah. The paleogeographic was altered in the late Bathonian to Callovian by back-arc extension north of a line extending from Cedar City, UT to Mina, NV. The palinspastic reconstruction implies the Paleozoic was tectonically stacked at the close of the Paleozoic.

  7. Proximal record of the 273 ka Poris caldera-forming eruption, Las Cañadas, Tenerife

    NASA Astrophysics Data System (ADS)

    Smith, Natasha J.; Kokelaar, B. Peter

    2013-11-01

    Lithofacies architecture analysis is applied to the most proximal exposures of the 273 ka Poris Formation, in the Diego Hernandez caldera wall of Las Cañadas. Here, the succession records an opening Plinian phase followed by generation of a pyroclastic density current (PDC) that was partly blocked by near-vent topography. The upper part of the current surmounted the barrier and deposited an ignimbrite veneer. During a hiatus in energetic flow, ash and various ash aggregates were deposited from a hybrid cloud comprising parts of both the Plinian and the co-ignimbrite plumes. Phreatomagmatic explosions then generated currents rich in fine-grained lithics; current waxing with local erosion was followed by pulsing-unsteady waning, recorded in repeated sets of graded tuff. Reversion to magmatic activity was marked by hybrid deposition, as coarse pumice fallout and juvenile ballistics entered pyroclastic currents to form stratified pumice-block tuff. Increasingly energetic flow is recorded in 9 m of mainly massive lapilli tuff that includes evidence of widespread scour and bypass; lithic-rich layers record incremental onset of edifice disruption due to magma withdrawal. Laterally variable stratification and load structures show that the PDC was unsteady and highly non-uniform at times, with locally rapid aggradation of gas-rich ignimbrite. Climactic edifice disruption is marked by a lithic-block layer in erosional contact with the underlying ignimbrite, recording intense pyroclastic current activity and widespread bypass of material to distal volcano slopes. Pumice-block breccia, 10 m thick and with blocks up to 1.2 m in diameter, forms the top of the succession and registers modification of the magmatic plumbing. The timing of collapse to form a major summit depression is uncertain. However, the abrupt termination of the proximal aggradation of coarse breccia, with no record there of any waning-stage pyroclastic currents, suggests subsidence at that time, conceivably

  8. Sr Isotopes and Migration of Prairie Mammoths (Mammuthus columbi) from Laguna de las Cruces, San Luis Potosi, Mexico

    NASA Astrophysics Data System (ADS)

    Solis-Pichardo, G.; Perez-Crespo, V.; Schaaf, P. E.; Arroyo-Cabrales, J.

    2011-12-01

    Asserting mobility of ancient humans is a major issue for anthropologists. For more than 25 years, Sr isotopes have been used as a resourceful tracer tool in this context. A comparison of the 87Sr/86Sr ratios found in tooth enamel and in bone is performed to determine if the human skeletal remains belonged to a local or a migrant. Sr in bone approximately reflects the isotopic composition of the geological region where the person lived before death; whereas the Sr isotopic system in tooth enamel is thought to remain as a closed system and thus conserves the isotope ratio acquired during childhood. Sr isotope ratios are obtained through the geologic substrate and its overlying soil, from where an individual got hold of food and water; these ratios are in turn incorporated into the dentition and skeleton during tissue formation. In previous studies from Teotihuacan, Mexico we have shown that a three-step leaching procedure on tooth enamel samples is important to assure that only the biogenic Sr isotope contribution is analyzed. The same Sr isotopic tools can function concerning ancient animal migration patterns. To determine or to discard the mobility of prairie mammoths (Mammuthus columbi) found at Laguna de las Cruces, San Luis Potosi, México the leaching procedure was applied on six molar samples from several fossil remains. The initial hypothesis was to use 87Sr/86Sr values to verify if the mammoth population was a mixture of individuals from various herds and further by comparing their Sr isotopic composition with that of plants and soils, to confirm their geographic origin. The dissimilar Sr results point to two distinct mammoth groups. The mammoth population from Laguna de Cruces was then not a family unit because it was composed by individuals originated from different localities. Only one individual was identified as local. Others could have walked as much as 100 km to find food and water sources.

  9. Tests of the Las Campanas Distant Cluster Survey from Confirmation Observations for the ESO Distant Cluster Survey

    NASA Astrophysics Data System (ADS)

    Gonzalez, Anthony H.; Zaritsky, Dennis; Simard, Luc; Clowe, Doug; White, Simon D. M.

    2002-11-01

    The ESO Distant Cluster Survey (EDisCS) is a photometric and spectroscopic study of the galaxy cluster population at two epochs, z~=0.5 and z~=0.8, drawn from the Las Campanas Distant Cluster Survey (LCDCS). We report results from the initial candidate-confirmation stage of the program and use these results to probe the properties of the LCDCS. Of the 30 candidates targeted, we find statistically significant overdensities of red galaxies near 28. Of the 10 additional candidates serendipitously observed within the fields of the targeted 30, we detect red galaxy overdensities near six. We test the robustness of the published LCDCS estimated redshifts to misidentification of the brightest cluster galaxy (BCG) in the survey data and measure the spatial alignment of the published cluster coordinates, the peak red galaxy overdensity, and the BCG. We conclude that for LCDCS clusters out to z~0.8, (1) the LCDCS coordinates agree with the centroid of the red galaxy overdensity to within 25" (~150 h-1 kpc) for 34 out of 37 candidates with 3 σ galaxy overdensities, (2) BCGs are typically coincident with the centroid of the red galaxy population to within a projected separation of 200 h-1 kpc (32 out of 34 confirmed candidates), (3) the red galaxy population is strongly concentrated, and (4) the misidentification of the BCG in the LCDCS causes a redshift error greater than 0.1 in 15%-20% of the LCDCS candidates. These findings together help explain the success of the surface brightness fluctuations detection method. Based on observations obtained in visitor and service modes at the ESO Very Large Telescope (VLT) as part of the Large Program 166.A-0162 (the ESO Distant Cluster Survey).

  10. Analysis of impacts of urban land use and land cover on air quality in the Las Vegas region using remote sensing information and ground observations

    USGS Publications Warehouse

    Xian, G.

    2007-01-01

    Urban development in the Las Vegas Valley of Nevada (USA) has expanded rapidly over the past 50 years. The air quality in the valley has suffered owing to increases from anthropogenic emissions of carbon monoxide, ozone and criteria pollutants of particular matter. Air quality observations show that pollutant concentrations have apparent heterogeneous characteristics in the urban area. Quantified urban land use and land cover information derived from satellite remote sensing data indicate an apparent local influence of urban development density on air pollutant distributions. Multi-year observational data collected by a network of local air monitoring stations specify that ozone maximums develop in the May and June timeframe, whereas minimum concentrations generally occur from November to February. The fine particulate matter maximum occurs in July. Ozone concentrations are highest on the west and northwest sides of the valley. Night-time ozone reduction contributes to the heterogeneous features of the spatial distribution for average ozone levels in the Las Vegas metropolitan area. Decreased ozone levels associated with increased urban development density suggest that the highest ozone and lowest nitrogen oxides concentrations are associated with medium to low density urban development in Las Vegas.

  11. New 40Ar/39Ar isotopic dates from Miocene volcanic rocks in the Lake Mead area and southern Las Vegas Range, Nevada

    USGS Publications Warehouse

    Harlan, S.S.; Duebendorfer, E.M.; Deibert, J.E.

    1998-01-01

    New 40Ar/39Ar dates on volcanic rocks interlayered with synextensional Miocene sedimentary rocks in the western Lake Mead area and southern end of the Las Vegas Range provide tight constraints on magmatism, basin formation, and extensional deformation in the Basin and Range province of southern Nevada. Vertical axis rotations associated with movement along the Las Vegas Valley shear zone occurred after 15.67??0.10 Ma (2??), based on a 40Ar/39Ar date from a tuff in the Gass Peak formation in the southern Las Vegas Range. Basaltic magmatism in the western Lake Mead area began as early as 13.28??0.09 Ma, based on a date from a basalt flow in the Lovell Wash Member of the Horse Spring Formation. Isotopic dating of a basalt from the volcanic rocks of Callville Mesa indicates that these rocks are as old as 11.41??0.14 Ma, suggesting that volcanic activity began shortly after formation of the Boulder basin, the extensional basin in which the informally named red sandstone unit was deposited. The red sandstone unit is at least as old as 11.70??0.08 Ma and contains megabreccia deposits younger than 12.93??0.10 Ma. This results shows that formation of the Boulder basin was associated with development of topographic relief that was probably generated by movement along the Saddle Island low-angle normal fault. Stratal tilting associated with extension occurred both prior to and after 11.5 Ma.

  12. Pseudomonas aeruginosa lasI/rhlI quorum sensing genes promote phagocytosis and aquaporin 9 redistribution to the leading and trailing regions in macrophages

    PubMed Central

    Holm, Angelika; Karlsson, Thommie; Vikström, Elena

    2015-01-01

    Pseudomonas aeruginosa controls production of its multiple virulence factors and biofilm development via the quorum sensing (QS) system. QS signals also interact with and affect the behavior of eukaryotic cells. Host water homeostasis and aquaporins (AQP) are essential during pathological conditions since they interfere with the cell cytoskeleton and signaling, and hereby affect cell morphology and functions. We investigated the contribution of P. aeruginosa QS genes lasI/rhlI to phagocytosis, cell morphology, AQP9 expression, and distribution in human macrophages, using immunoblotting, confocal, and nanoscale imaging. Wild type P. aeruginosa with a functional QS system was a more attractive prey for macrophages than the lasI/rhlI mutant lacking the production of QS molecules, 3O-C12-HSL, and C4-HSL, and associated virulence factors. The P. aeruginosa infections resulted in elevated AQP9 expression and relocalization to the leading and trailing regions in macrophages, increased cell area and length; bacteria with a functional QS system lasI/rhlI achieved stronger responses. We present evidence for a new role of water fluxes via AQP9 during bacteria–macrophage interaction and for the QS system as an important stimulus in this process. These novel events in the interplay between P. aeruginosa and macrophages may influence on the outcome of infection, inflammation, and development of disease. PMID:26388857

  13. A Tale of two Cities: Photoacoustic and Aethalometer Measurements Comparisons of Light Absorption in Mexico City and Las Vegas, NV, USA

    NASA Astrophysics Data System (ADS)

    Paredes-Miranda, G.; Arnott, W. P.; Marley, N. A.; Gaffney, J. S.

    2007-05-01

    As part of the Megacity Impacts on Regional and Global Environments, MIRAGE-Mex deployment to Mexico City in the period of 30 days, March 2006, a suite of photoacoustic spectrometers (PAS; W. Arnott & G. Paredes), nephelometer scattering, and aetholemeter absorption instruments (N. Marley & J.Gaffney) were installed to measure at ground level the light absorption and scattering by aerosols at the urban site at Instituto Mexicano del Petroleo (Mexican Oil Institute, denoted by IMP). This IMP site gave in-situ characterization of the Mexico City plume under favorable wind conditions. The PAS used at IMP operates at 532 nm, and conveniently allowed for characterization of gaseous absorption at this wavelength as well. Light scattering measurements are accomplished within the PAS by the reciprocal nephelometery method. In the urban site the aerosol absorption coefficient typically varies between 20 and 180 Mm-1 during the course of the day and significant diurnal variation of the aerosol single scattering albedo was observed. The Las Vegas, NV site was located at East Charleston Street on January-February, 2003. In east Las Vegas typical westerly winds carry the city plume across the site. Comparisons of PAS aerosol light absorption and aetholemeter absorption measurements at 521 nm at both Las Vegas NV and Mexico City sites will be presented. We will also present a broad overview of the diurnal variation of the scattering and absorption as well as the single scattering albedo and fraction of absorption due to gases at the sites in relation to secondary aerosol formation.

  14. The Las Vegas Thesis

    ERIC Educational Resources Information Center

    Sughrua, William

    2010-01-01

    Following "reflexive ethnography" and utilizing an approach of "performative narrative" and "layered text", this article explores how Bachelor of Arts students in the Teaching of English as a Foreign Language program at a public university in Mexico successfully manage the writing of an inductive-oriented thesis in English by resisting…

  15. Real-Time Access to Altimetry and Operational Oceanography Products via OPeNDAP/LAS Technologies : the Example of Aviso, Mercator and Mersea Projects

    NASA Astrophysics Data System (ADS)

    Baudel, S.; Blanc, F.; Jolibois, T.; Rosmorduc, V.

    2004-12-01

    The Products and Services (P&S) department in the Space Oceanography Division at CLS is in charge of diffusing and promoting altimetry and operational oceanography data. P&S is so involved in Aviso satellite altimetry project, in Mercator ocean operational forecasting system, and in the European Godae /Mersea ocean portal. Aiming to a standardisation and a common vision and management of all these ocean data, these projects led to the implementation of several OPeNDAP/LAS Internet servers. OPeNDAP allows the user to extract via a client software (like IDL, Matlab or Ferret) the data he is interested in and only this data, avoiding him to download full information files. OPeNDAP allows to extract a geographic area, a period time, an oceanic variable, and an output format. LAS is an OPeNDAP data access web server whose special feature consists in the facility for unify in a single vision the access to multiple types of data from distributed data sources. The LAS can make requests to different remote OPeNDAP servers. This enables to make comparisons or statistics upon several different data types. Aviso is the CNES/CLS service which distributes altimetry products since 1993. The Aviso LAS distributes several Ssalto/Duacs altimetry products such as delayed and near-real time mean sea level anomaly, absolute dynamic topography, absolute geostrophic velocities, gridded significant wave height and gridded wind speed modulus. Mercator-Ocean is a French operational oceanography centre which distributes its products by several means among them LAS/OPeNDAP servers as part of Mercator Mersea-strand1 contribution. 3D ocean description (temperature, salinity, current and other oceanic variables) of the North Atlantic and Mediterranean are real-time available and weekly updated. LAS special feature consisting in the possibility of making requests to several remote data centres with same OPeNDAP configurations particularly fitted to Mersea strand-1 problematics. This European

  16. Site formation and chronology of the new Paleolithic site Sima de Las Palomas de Teba, southern Spain

    NASA Astrophysics Data System (ADS)

    Kehl, Martin; Burow, Christoph; Cantalejo, Pedro; Domínguez-Bella, Salvador; Durán, Juan José; Henselowsky, Felix; Klasen, Nicole; Linstädter, Jörg; Medianero, Javier; Pastoors, Andreas; Ramos, José; Reicherter, Klaus; Schmidt, Christoph; Weniger, Gerd-Christian

    2016-03-01

    The newly identified Paleolithic site Sima de Las Palomas de Teba hosts an almost seven-m-thick sediment profile investigated here to elucidate the rock shelter's chronostratigraphy and formation processes. At its base, the sediment sequence contains rich archeological deposits recording intensive occupation by Neanderthals. Luminescence provides a terminus ante quem of 39.4 ± 2.6 ka or 44.9 ± 4.1 ka (OSL) and 51.4 ± 8.4 ka (TL). This occupation ended with a rockfall event followed by accumulation of archeologically sterile sediments. These were covered by sediments containing few Middle Paleolithic artifacts, which either indicate ephemeral occupation by Neanderthals or reworking as suggested by micromorphological features. Above this unit, scattered lithic artifacts of undiagnostic character may represent undefined Paleolithic occupations. Sediment burial ages between about 23.0 ± 1.5 ka (OSL) and 40.5 ± 3.4 ka (pIRIR) provide an Upper Paleolithic chronology for sediments deposited above the rockfall. Finally, a dung-bearing Holocene layer in the uppermost part of the sequence contains a fragment of a human mandible dated to 4032 ± 39 14C yr BP. Overall, the sequence represents an important new site for studying the end of Neanderthal occupation in southern Spain. Supplementary Figure S2: Preheat-plateau and dose-recovery test results for OSL on fine-grained quartz of samples CP7. Aliquots for the dose-recovery test were administered a dose of 40 Gy after removing the natural signal by blue stimulation for 150 s at 125°C and 80% optical power. Supplementary Figure S3: Dependence of equivalent dose on prior IR stimulation temperature for samples CP1, CP3 and CP7. For each sample and pIRIR protocol six aliquots were used while increasing the first IR stimulation temperature in steps of 30°C from 50°C to 140°C and to 180°C. Data are normalized to the pIRIR De obtained with a first IR stimulation at 50°C. Supplementary Figure S4: Regenerative TL glow

  17. Analysis of Individual Carbonaceous Particles Emitted from the Las Conchas Wildfire, Los Alamos, NM, in June-July 2011

    NASA Astrophysics Data System (ADS)

    Mazzoleni, C.; China, S.; Gorkowski, K.; Flowers, B. A.; Aiken, A. C.; Dubey, M. K.

    2012-12-01

    Carbonaceous aerosol emitted from biomass burning contributes significantly to atmospheric aerosol loadings regionally and globally. The net direct radiative forcing of biomass burning aerosol can be positive and/or negative and this depends on its composition, morphology and mixing state. Biomass burning aerosols can also change the cloud properties as they can act as cloud condensation nuclei. In this study we investigated biomass burning particles emitted from the Las Conchas wildfire in northern New Mexico that started on June 26, 2011 and burned an area of 245 square miles. Aerosol samples were collected on nucleopore filters at the Los Alamos National Laboratory during the third week of the wildfire event. Individual particles (~4000) were investigated using field-emission scanning electron microscopy and energy dispersive X-ray spectroscopy (EDS) to distinguish different carbonaceous particles and their shape, size, elemental composition and mixing state. A thermo-denuder was used to remove compounds that are volatile at temperatures up to 200 C, leaving behind the black carbon and any compounds that did not volatize completely. Smoke particles consisted of a) tar balls, which are amorphous spherical carbonaceous organic aerosols; b) organic particles with inorganic inclusions, c) soot particles and (d) soot with various inclusions. Two distinct kinds of tar balls, "electronically" dark and bright, were found using the field-emission scanning electron microscopy and were characterized for ambient and denuded conditions to understand coating effects and aging. It was found that dark tar balls are generally larger in size than the bright ones. Additionally, the difference between the size of ambient-bright and the size of denuded-bright tar balls was larger than the difference between the size of ambient-dark and the size of denuded-dark tar balls. EDS analysis showed that 70% of the dark tar balls had higher (~60%) relative oxygen content than in the bright

  18. Providing Meaningful Learning for Students of the Sixth Grade of Middle School: a Study on the Moon Phases. (Breton Title: Propiciando Aprendizagem Significativa Para Alunos do Sexto Ano do Ensino Fundamental: um Estudo sobre as Fases da Lua.) Propiciando el Aprendizaje Significativo Para Alumnos del Sexto Nivel de la Educación General Básica: un Estudio sobre Las Fases de la Luna

    NASA Astrophysics Data System (ADS)

    Darroz, Luiz Marcelo; Samudio Pérez, Carlos Ariel; da Rosa, Cleci Werner; Heineck, Renato

    2012-07-01

    ía del Aprendizaje Significativo de David Ausubel, se buscó desenvolver la propuesta a partir de un modelo didáctico que simula las Fases de la Luna, usando como base las concepciones previas de los estudiantes. Los indicios del aprendizaje fueron verificados a través de registros de memorias de la actividad. Por los resultados obtenidos creemos que la propuesta alcanzó sus objetivos, una vez que los estudiantes consiguieron identificar y transferir el fenómeno de las fases de la Luna para nuevos contextos. Así, se concluye que una metodología con enfoque en un contenido significativo para el estudiante es fundamental para la construcción y comprensión genuina de lo que está siendo aprendido.

  19. Breakfast of champions or kiss of death? Survival and sexual performance of protein-fed, sterile Mediterranean fruit flies (Diptera: Tephritidae)

    SciTech Connect

    Yuval, B.; Maor, M.; Levy, K.; Kaspi, R.; Taylor, P.; Shelly, T.

    2007-03-15

    The sterile insect technique (SIT) is increasingly being used around the world to control Ceratitis capitata (Wiedemann) (Diptera: Tephritidae), the Mediterranean fruit fly as part of an area-wide integrated approach. One option that may improve the effectiveness of the SIT, by increasing the sexual competitiveness of released sterile males, consists of feeding males protein during the post-teneral stage, a diet that increases sexual performance of wild males. We examine the effects of diet on the successive hurdles males must overcome in order to inseminate females, i.e., joining leks, copulating females, having their sperm stored and inhibition of female remating. In addition, we address the effects of diet on post-release foraging success, longevity, and the ability to withstand starvation. While protein feeding universally increases the sexual success of wild males, its effect on sterile males varies with strain, experimental settings, and environmental conditions. In some cases, treatments that resulted in the best sexual performance were significantly associated with increased vulnerability to starvation. However, no particular diet affected the ability of sterile males to find nutrients in the field when these where available. We suggest it may be better to release relatively short-lived flies that are highly competitive, rather than long-lived, sexually ineffective ones. (author) [Spanish] El uso de la tecnica de insecto esteril (TIE) esta aumentando alrededor del mundo para el control de Ceratitis capitata (Wiedemann) (Diptera: Tephritidae), la mosca mediterranea de la fruta como parte de un enfoque integrado por toda el area. Una opcion que puede mejorar la eficiencia de TIE, por medio del aumento de la capacidad de los machos esteriles liberados para competir, consiste en la alimentacion de los machos con proteina durante la etapa de pos-teneral, una dieta que aumenta el desempeno sexual de los machos naturales. Nosotros examinamos los efectos de la

  20. The Managua Graben and Las Sierras-Masaya volcanic complex (Nicaragua); pull-apart localization by an intrusive complex: results from analogue modeling

    NASA Astrophysics Data System (ADS)

    Girard, Guillaume; van Wyk de Vries, Benjamin

    2005-06-01

    There is a well-documented association between pull-apart basins in strike-slip zones and large volcanic caldera complexes. Las Sierras-Masaya volcanic complex, Nicaragua, is a large basaltic lava and ignimbrite shield with nested calderas. The widest caldera is partly underlain by a large and dense intrusive complex, evidenced by a positive gravity anomaly. The Las Sierras Caldera, relating to this cumulate complex, is less than 30,000 years old and is probably still hot and ductile. The inner Masaya Caldera hosts an active magmatic system. The volcanic complex is in a dextral transtensional tectonic context of the Nicaraguan Depression. The highly active Managua Graben is on the northern part of the volcano. We speculate that the graben and volcano are linked tectonically, with the graben initiating in response of a regional stress field modified around the dense, ductile intrusive complex. Previous field work and reappraisal of structures with digital elevation model morphological analysis show that the volcano is surrounded by a rhombic fault pattern that may form a nascent pull-apart basin. We have done scaled analogue models to test the effect of intrusion density and rheology anomalies on strike-slip fault geometries. The models show that intrusion density variations alone do not significantly change fault patterns. In contrast, ductile rocks (silicone in the models as analogue for hot mafic intrusive rocks) markedly alter strike-slip fault patterns. In transtension the presence of a ductile intrusion causes the formation of a pull-apart, while in pure strike-slip or transpression, uplift and thrusting is generated. Pull-apart and uplift structures are rhomb-shaped even when the ductile inclusion is circular. We conclude that a pull-apart is developing at Las Sierras-Masaya volcanic complex in response to the transtensive regional deformation regime and the dense, ductile intrusive complex. We suggest that the volcano and graben are one dynamic system and

  1. First records of Canis dirus and Smilodon fatalis from the late Pleistocene Tule Springs local fauna, upper Las Vegas Wash, Nevada

    PubMed Central

    Springer, Kathleen B.

    2016-01-01

    Late Pleistocene groundwater discharge deposits (paleowetlands) in the upper Las Vegas Wash north of Las Vegas, Nevada, have yielded an abundant and diverse vertebrate fossil assemblage, the Tule Springs local fauna (TSLF). The TSLF is the largest open-site vertebrate fossil assemblage dating to the Rancholabrean North American Land Mammal Age in the southern Great Basin and Mojave Desert. Over 600 discrete body fossil localities have been recorded from the wash, including an area that now encompasses Tule Springs Fossil Beds National Monument (TUSK). Paleowetland sediments exposed in TUSK named the Las Vegas Formation span the last 250 ka, with fossiliferous sediments spanning ∼100–13 ka. The recovered fauna is dominated by remains of Camelopsand Mammuthus, and also includes relatively common remains of extinct Equusand Bisonas well as abundant vertebrate microfaunal fossils. Large carnivorans are rare, with only Puma concolor and Panthera atrox documented previously. Postcranial remains assigned to the species Canis dirus (dire wolf) and Smilodon fatalis (sabre-toothed cat) represent the first confirmed records of these species from the TSLF, as well as the first documentation of Canis dirus in Nevada and the only known occurrence of Smilodonin southern Nevada. The size of the recovered canid fossil precludes assignment to other Pleistocene species of Canis. The morphology of the felid elements differentiates them from other large predators such as Panthera, Homotherium, and Xenosmilus, and the size of the fossils prevents assignment to other species of Smilodon. The confirmed presence of S. fatalis in the TSLF is of particular interest, indicating that this species inhabited open habitats. In turn, this suggests that the presumed preference of S. fatalis for closed-habitat environments hunting requires further elucidation. PMID:27366649

  2. Temperature-Dependent Expression of phzM and Its Regulatory Genes lasI and ptsP in Rhizosphere Isolate Pseudomonas sp. Strain M18▿

    PubMed Central

    Huang, Jiaofang; Xu, Yuquan; Zhang, Hongyan; Li, Yaqian; Huang, Xianqing; Ren, Bin; Zhang, Xuehong

    2009-01-01

    Pseudomonas sp. strain M18, an effective biological control agent isolated from the melon rhizosphere, has a genetic background similar to that of the opportunistic human pathogen Pseudomonas aeruginosa PAO1. However, the predominant phenazine produced by strain M18 is phenazine-1-carboxylic acid (PCA) rather than pyocyanin (PYO); the quantitative ratio of PCA to PYO is 105 to 1 at 28°C in strain M18, while the ratio is 1 to 2 at 37°C in strain PAO1. We first provided evidence that the differential production of the two phenazines in strains M18 and PAO1 is related to the temperature-dependent and strain-specific expression patterns of phzM, a gene involved in the conversion of PCA to PYO. Transcriptional levels of phzM were measured by quantitative real-time PCR, and the activities of both transcriptional and translational phzM′-′lacZ fusions were determined in strains M18 and PAO1, respectively. Using lasI::Gm and ptsP::Gm inactivation M18 mutants, we further show that expression of the phzM gene is positively regulated by the quorum-sensing protein LasI and negatively regulated by the phosphoenolpyruvate phosphotransferase protein PtsP. Surprisingly, the lasI and ptsP regulatory genes were also expressed in a temperature-dependent and strain-specific manner. The differential production of the phenazines PCA and PYO by strains M18 and PAO1 may be a consequence of selective pressure imposed on P. aeruginosa PAO1 and its relative M18 in the two different niches over a long evolutionary process. PMID:19717631

  3. Detection of Pseudomonas aeruginosa by a triplex polymerase chain reaction assay based on lasI/R and gyrB genes.

    PubMed

    Aghamollaei, Hosseine; Moghaddam, Mehrdad M; Kooshki, Hamid; Heiat, Mohammad; Mirnejad, Reza; Barzi, Nastaran S

    2015-01-01

    Pseudomonas aeruginosa is a nosocomial pathogen, which, due to its inherent and acquired resistance to a wide range of antibiotics, causes high mortality rates. Therefore, rapid detection of the bacterium with high specificity and sensitivity plays a critical role in the control of the pathogenic bacterium. The aim of this study was to evaluate the accuracy and specificity of a prompt detection of the bacterium based on a triplex polymerase chain reaction that amplifies the lasI, lasR and gyrB genes. For this purpose, 30 clinical isolates of P. aeruginosa and 30 wound biopsy samples were retrieved from clinical diagnostic laboratories. After the extraction of the chromosomal DNA, the desired genes were amplified using uniplex and triplex PCR with appropriate primers. The specificity of the primers was evaluated by a comparison of the PCR results for P. aeruginosa clinical samples and non-Pseudomonas species control samples. The sensitivity of the primers was determined using a serial dilution of the genomic DNA template (100 ng to 100 fg) and by a comparison of the PCR and bacterial culture results. The results showed that the triplex PCR assay was positive for all of the samples (100%), while the PCR identifications were negative for non-Pseudomonas species. Additionally, at 10(-4) and 10(-5) diluted genomic DNA from P. aeruginosa (10 pg and 1 pg), the triplex PCR test was positive for the Las and gyrB genes in all of the samples, respectively. Based on these results, the designed primers can be used for the rapid, specific and sensitive diagnosis of P. aeruginosa in a triplex PCR assay. PMID:25863575

  4. First records of Canis dirus and Smilodon fatalis from the late Pleistocene Tule Springs local fauna, upper Las Vegas Wash, Nevada.

    PubMed

    Scott, Eric; Springer, Kathleen B

    2016-01-01

    Late Pleistocene groundwater discharge deposits (paleowetlands) in the upper Las Vegas Wash north of Las Vegas, Nevada, have yielded an abundant and diverse vertebrate fossil assemblage, the Tule Springs local fauna (TSLF). The TSLF is the largest open-site vertebrate fossil assemblage dating to the Rancholabrean North American Land Mammal Age in the southern Great Basin and Mojave Desert. Over 600 discrete body fossil localities have been recorded from the wash, including an area that now encompasses Tule Springs Fossil Beds National Monument (TUSK). Paleowetland sediments exposed in TUSK named the Las Vegas Formation span the last 250 ka, with fossiliferous sediments spanning ∼100-13 ka. The recovered fauna is dominated by remains of Camelopsand Mammuthus, and also includes relatively common remains of extinct Equusand Bisonas well as abundant vertebrate microfaunal fossils. Large carnivorans are rare, with only Puma concolor and Panthera atrox documented previously. Postcranial remains assigned to the species Canis dirus (dire wolf) and Smilodon fatalis (sabre-toothed cat) represent the first confirmed records of these species from the TSLF, as well as the first documentation of Canis dirus in Nevada and the only known occurrence of Smilodonin southern Nevada. The size of the recovered canid fossil precludes assignment to other Pleistocene species of Canis. The morphology of the felid elements differentiates them from other large predators such as Panthera, Homotherium, and Xenosmilus, and the size of the fossils prevents assignment to other species of Smilodon. The confirmed presence of S. fatalis in the TSLF is of particular interest, indicating that this species inhabited open habitats. In turn, this suggests that the presumed preference of S. fatalis for closed-habitat environments hunting requires further elucidation. PMID:27366649

  5. 210Pb-derived history of PAH and PCB accumulation in sediments of a tropical inner lagoon (Las Matas, Gulf of Mexico) near a major oil refinery

    NASA Astrophysics Data System (ADS)

    Ruiz-Fernández, Ana Carolina; Sprovieri, Mario; Piazza, Rossano; Frignani, Mauro; Sanchez-Cabeza, Joan-Albert; Feo, Maria Luisa; Bellucci, Luca Giorgio; Vecchiato, Marco; Pérez-Bernal, Libia Hascibe; Páez-Osuna, Federico

    2012-04-01

    Concentrations of polycyclic aromatic hydrocarbons (PAHs) and polychlorinated biphenyls (PCBs) were measured in a sediment core from the tropical freshwater inner lagoon of Las Matas, near the petroleum industrial area of Minatitlán-Coatzacoalcos, in the Gulf of Mexico. A 210Pb-derived chronology was used to reconstruct the historical PAH and PCB accumulation in the site during one century (1906-2005). Both geochemical and sedimentological data indicated that a major change occurred in 1947 ± 4, including a shift to coarser sediments and a significant decrease of Al, Li, Fe, organic C and total N contents. This was likely due to the changes in hydrology caused by the confinement of Las Matas Lagoon due to the construction of the Trans-Isthmus road in 1946. PAHs in these samples show relatively low concentrations (259-1176 ng g-1), and the congener relative abundances indicate the influence of pyrogenic (petroleum combustion) sources. Total PCB concentrations in the sediments ranged from 24 to 77 ng g-1, and are composed by low chlorinated PCBs, with 3- and 4-CB as the prevalent species (51-65% and 29-40%, respectively). PAHs and PCBs were detected at depths corresponding to the early 1900s, when Minatitlán refinery started operations, although their time evolution appears to be influenced by different accumulation processes. The PCB background is most likely produced by the combustion of natural organic matter, and an industrial contribution can be recognized when normalizing with OC contents. We concluded that atmospheric deposition is the most significant source of PAHs and PCBs for this water body. This study also provided evidence of the alteration of the wetlands surrounding this industrial area due to urbanization; the fragmentation and alteration of Las Matas Lagoon hydrology contributes to the gradual loss of the wetlands in the zone.

  6. Effects of illegal harvest of eggs on the population decline of leatherback turtles in Las Baulas Marine National Park, Costa Rica.

    PubMed

    Tomillo, Pilar Santidrián; Saba, Vincent S; Piedra, Rotney; Paladino, Frank V; Spotila, James R

    2008-10-01

    Within 19 years the nesting population of leatherback turtles (Dermochelys coriacea) at Parque Nacional Marino Las Baulas declined from 1500 turtles nesting per year to about 100. We analyzed the effects of fishery bycatch and illegal harvesting (poaching) of eggs on this population. We modeled the population response to different levels of egg harvest (90, 75, 50, and 25%) and the effect of eradicating poaching at different times during the population decline. We compared effects of 90% poaching with those of 20% adult mortality because both of these processes were present in the population at Las Baulas. There was a stepwise decline in number of nesting turtles at all levels of egg harvest. Extirpation times for different levels of poaching ranged from 45 to 282 years. The nesting population declined more slowly and survived longer with 20% adult mortality (146 years) than it did with 90% poaching (45 years). Time that elapsed until poaching stopped determined the average population size at which the population stabilized, ranging from 90 to 420 nesting turtles. Our model predicted that saving clutches lost naturally would restore the population when adult mortality rates were low and would contribute more to population recovery when there were short remigration intervals between nesting seasons and a large proportion of natural loss of clutches. Because the model indicated that poaching was the most important cause of the leatherback decline at Las Baulas, protecting nests on the beach and protecting the beach from development are critical for survival of this population. Nevertheless, the model predicted that current high mortality rates of adults will prevent population recovery. Therefore, protection of the beach habitat and nests must be continued and fishery bycatch must be reduced to save this population. PMID:18637915

  7. Inverse modeling using PS-InSAR for improved calibration of hydraulic parameters and prediction of future subsidence for Las Vegas Valley, USA

    NASA Astrophysics Data System (ADS)

    Burbey, T. J.; Zhang, M.

    2015-11-01

    Las Vegas Valley has had a long history of surface deformation due to groundwater pumping that began in the early 20th century. After nearly 80 years of pumping, PS-InSAR interferograms have revealed detailed and complex spatial patterns of subsidence in the Las Vegas Valley area that do not coincide with major pumping regions. High spatial and temporal resolution subsidence observations from InSAR and hydraulic head data were used to inversely calibrate transmissivities (T), elastic and inelastic skeletal storage coefficients (Ske and Skv) of the developed-zone aquifer and conductance (CR) of the basin-fill faults for the entire Las Vegas basin. The results indicate that the subsidence observations from PS-InSAR are extremely beneficial for accurately quantifying hydraulic parameters, and the model calibration results are far more accurate than when using only water-levels as observations, and just a few random subsidence observations. Future predictions of land subsidence to year 2030 were made on the basis of existing pumping patterns and rates. Simulation results suggests that subsidence will continue in northwest subsidence bowl area, which is expected to undergo an additional 11.3 cm of subsidence. Even mitigation measures that include artificial recharge and reduced pumping do not significantly reduce the compaction in the northwest subsidence bowl. This is due to the slow draining of thick confining units in the region. However, a small amount of uplift of 0.4 cm is expected in the North and Central bowl areas over the next 20 years.

  8. Verprolin function in endocytosis and actin organization. Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain.

    PubMed

    Thanabalu, Thirumaran; Rajmohan, Rajamuthiah; Meng, Lei; Ren, Gang; Vajjhala, Parimala R; Munn, Alan L

    2007-08-01

    Vrp1p (verprolin, End5p) is the yeast ortholog of human Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP). Vrp1p localizes to the cortical actin cytoskeleton, is necessary for its polarization to sites of growth and is also essential for endocytosis. At elevated temperature, Vrp1p becomes essential for growth. A C-terminal Vrp1p fragment (C-Vrp1p) retains the ability to localize to the cortical actin cytoskeleton and function in actin-cytoskeleton polarization, endocytosis and growth. Here, we demonstrate that two submodules in C-Vrp1p are required for actin-cytoskeleton polarization: a novel C-terminal actin-binding submodule (CABS) that contains a novel G-actin-binding domain, which we call a verprolin homology 2 C-terminal (VH2-C) domain; and a second submodule comprising the Las17p-binding domain (LBD) that binds Las17p (yeast WASP). The LBD localizes C-Vrp1p to membranes and the cortical actin cytoskeleton. Intriguingly, the LBD is sufficient to restore endocytosis and growth at elevated temperature to Vrp1p-deficient cells. The CABS also restores these functions, but only if modified by a lipid anchor to provide membrane association. Our findings highlight the role of Las17p binding for Vrp1p membrane association, suggest general membrane association may be more important than specific targeting to the cortical actin cytoskeleton for Vrp1p function in endocytosis and cell growth, and suggest that Vrp1p binding to individual effectors may alter their physiological activity. PMID:17635585

  9. Evaluation of S-101 course Supervisors' Orientation to Occupational Safety in DOE'' taught in Las Vegas, Nevada, October 26--29, 1992

    SciTech Connect

    Wright, T.S.

    1993-03-01

    This report summarizes trainee evaluations for the Safety Training Section course, Supervisors' Orientation to Occupational Safety in DOE'', (S-101) which was conducted October 26--29, 1992 at EG G Measurement, in Las Vegas, Nevada. Sections 1.1 and 1.2 of this report summarize the quantitative course evaluations that trainees provided upon completion of the course. Sections 2.0 and 3.0 provide examination results, and recommendations for improvement. Appendix A provides a transcript of the trainees' written comments and Appendix B presents a copy of the course evaluation form that students were asked to complete.

  10. Array analyses of volcanic earthquakes and tremor recorded at Las Cañadas caldera (Tenerife Island, Spain) during the 2004 seismic activation of Teide volcano

    NASA Astrophysics Data System (ADS)

    Almendros, Javier; Ibáñez, Jesús M.; Carmona, Enrique; Zandomeneghi, Daria

    2007-02-01

    We analyze data from three seismic antennas deployed in Las Cañadas caldera (Tenerife) during May-July 2004. The period selected for the analysis (May 12-31, 2004) constitutes one of the most active seismic episodes reported in the area, except for the precursory seismicity accompanying historical eruptions. Most seismic signals recorded by the antennas were volcano-tectonic (VT) earthquakes. They usually exhibited low magnitudes, although some of them were large enough to be felt at nearby villages. A few long-period (LP) events, generally associated with the presence of volcanic fluids in the medium, were also detected. Furthermore, we detected the appearance of a continuous tremor that started on May 18 and lasted for several weeks, at least until the end of the recording period. It is the first time that volcanic tremor has been reported at Teide volcano. This tremor was a small-amplitude, narrow-band signal with central frequency in the range 1-6 Hz. It was detected at the three antennas located in Las Cañadas caldera. We applied the zero-lag cross-correlation (ZLCC) method to estimate the propagation parameters (back-azimuth and apparent slowness) of the recorded signals. For VT earthquakes, we also determined the S-P times and source locations. Our results indicate that at the beginning of the analyzed period most earthquakes clustered in a deep volume below the northwest flank of Teide volcano. The similarity of the propagation parameters obtained for LP events and these early VT earthquakes suggests that LP events might also originate within the source volume of the VT cluster. During the last two weeks of May, VT earthquakes were generally shallower, and spread all over Las Cañadas caldera. Finally, the analysis of the tremor wavefield points to the presence of multiple, low-energy sources acting simultaneously. We propose a model to explain the pattern of seismicity observed at Teide volcano. The process started in early April with a deep magma

  11. Phenotypical and genetic characterization of Trichosporon sp. HP-2023. A yeast isolate from Las Yungas rainforest (Tucumán, Argentina) with dye-decolorizing ability.

    PubMed

    Pajot, Hipólito F; Figueroa, Lucía I C; Spencer, John F T; Fariña, Julia I

    2008-08-01

    A basidiomycetous yeast isolated from Las Yungas rainforest (Tucumán, Argentina) and arbitrarily named HP-2023 was selected based on its outstanding textile dye decolorizing ability. Complete decolorization of Vilmafix Red 7B-HE and Vilmafix Blue RR-BB (200 mg/l) was achieved after 16 h of cultivation. Yeast characterization was accomplished by means of both traditional and molecular methods. Results concerning molecular fingerprinting and phenotypic characterization led to identify it as Trichosporon sp., closely related to the T. multisporum-T. laibachii complex. The present work represents the first description of a Trichosporon yeast involved in reactive textile dye decolorization processes. PMID:18437525

  12. Gaseous Mercury Monitoring at a Complex Source: The Las Cuevas Decommissioned Mining Complex and Current Hg Storage Facility (Almadén District, Spain)

    NASA Astrophysics Data System (ADS)

    Higueras, P. L.; Esbri, J. M.; Llanos, W. R.; Oyarzun, R.; Martinez-Coronado, A.; Grupo de Estudios En Minería Y Medioambiente-Gemm

    2010-12-01

    The Las Cuevas decommissioned mining complex was the third in importance in the world’s largest mercury mining district: Almadén (south-central Spain). Mining took place during two well differentiated periods: 1. Roman time; and 2. From 1982 to 2000. In 2004 the mine was transformed into a mercury storage and handling facility, away from urban areas. Furthermore, the area served as a test site for the design and implementation of a mercury safe storage vessel, a study funded by European LIFE-Env programme (Project MERSADE, LIFE06 ENV/ES/PREP/03) (Llanos et al., 2010). On this basis, Las Cuevas site can be regarded as a complex source of atmospheric mercury for the local environmental compartments, including emissions from the plant activity, partly reclamated old mineral dumps, contaminated soils, and other minor sources, such as cavities produced by mine collapse. We studied the emissions with two LUMEX RA-915+ Hg analyzers, one LUMEX RA-915Light device and a complete TEKRAN equipment, including Mercury Speciation Unit (model 1130) and Particulate Mercury Unit (Model 1135). Data has been treated with ISC-AERMOD program, in order to obtain models for contamination plumes derived from Las Cuevas whole area. The results confirm the mercury storage facility as the main local source for mercury, releasing some 3,15 kg Hg y-1, whereas contaminated soils and reclamated dumps represent local minor sources. Over 99,9% of local atmospheric mercury is Gaseous Elemental Mercury, with Reactive Gaseous Mercury representing 0,25 per mil, and particulate bound mercury, 1,8 per mil. Citation: Llanos, W.; Higueras, P.; Oyarzun, R.; Esbrí, J.M.; López-Berdonces, M.A.; García-Noguero, E.M.; Martínez-Coronado, A. (2010) A preliminary environmental assessment at the site of the European prototype installation of a safe deposit for surplus mercury from industry: The Las Cuevas mining complex, Almadén District, Spain. Science of the Total Environment, 408: 4901-4905.

  13. Estimating Climate Resilience for Conservation across Geophysical Settings

    PubMed Central

    ANDERSON, MARK G; CLARK, MELISSA; SHELDON, ARLENE OLIVERO

    2014-01-01

    poder conservar la diversidad biológica mientras permiten que las especies y las comunidades se reorganicen con respecto al clima cambiante. Desarrollamos y probamos tal método, el cual basamos en características físicas asociadas con la diversidad ecológica y la capacidad de recuperación del sitio con respecto al cambio climático, en el noreste de Norteamérica. Mapeamos comprensivamente 30 escenarios geofísicos distintos basados en la geología y la elevación. Dentro de cada escenario geofísico identificamos sitios que estaban conectados por una cubierta natural y que tenían relativamente más microclimas indicados por la topografía diversa y los gradientes de elevación. Hicimos esto al puntuar cada hexágono de 450 ha en la región con estas dos características y al seleccionar aquellos que tuvieron una puntuación >SD 0.5 por encima del puntaje combinado promedio para cada escenario. Nuestra hipótesis fue que estos sitios con altas puntuaciones tuvieron la mayor capacidad de recuperación. Los comparamos con los sitios seleccionados por The Nature Conservancy por sus poblaciones de alta calidad de especies raras y sus ocurrencias de comunidades naturales. Los sitios con altos puntajes capturaron significativamente más de los sitios de biodiversidad de lo que se esperaba por casualidad (p < 0.0001): 75% de las 414 especies objetivo, 49% de las 4592 localidades de especies objetivo y 53% de las 2710 localidades de comunidades objetivo. Los escenarios de lecho rocoso calcáreo, arena gruesa y limo fino tuvieron puntos marcadamente más bajos para la capacidad de recuperación estimada y tuvieron niveles bajos de protección permanente de suelo (en promedio 7%). Ya que nuestro método identifica – para cada escenario geofísico – sitios que tienen mayor probabilidad de retener especies y funciones más tiempo bajo un clima cambiante, revela baluartes naturales para la conservación futura que también capturaría biodiversidad existente sustancial y

  14. A UV-vis study of the effects of alcohols on formation and stability of Mn(por)(O)(OAc) complexes

    NASA Astrophysics Data System (ADS)

    Mohajer, Daryoush; Jahanbani, Maryam

    2012-06-01

    Interactions of three different (acetato) (tetraarylporphyrinato) manganese (III) MnIII(por) with tetra-n-butylammonium hydrogen monopersulfate (n-Bu4NHSO5), in the presence of excess tetra-n-butylammonium acetate (n-Bu4NOAc) and in the absence or presence of various alcohols (alcohols = CH3OH, C2H5OH, i-C3H7OH, t-C4H9OH) in CH2Cl2, were monitored by their UV-vis spectral changes, under identical conditions, at room temperature. (Acetato) (tetrakispentafluorophenylporphyrinato) manganese (III) MnIII(tpfpp)(OAc) and (acetato) (tetramesitylporphyrinato) manganese (III) MnIII(tmp)(OAc) produced their corresponding high valent Mn(tpfpp)(O)(OAc) and Mn(tmp)(O)(OAc) both in the absence or presence of alcohols. Whereas, (acetato) (tetraphenylporphyrinato) manganese (III) MnIII(tpp)(OAc) only generated Mn(tpp)(O)(OAc) in the presence of less bulky alcohols. In the absence of alcohols or in the presence of t-C4H9OH, the UV-vis spectra displayed a very weak sign of formation of Mn(tpp)(O)(OAc) complex. It was observed that alcohols generally increased the rate of formation of Mn-oxo species in accordance with their acidity or hydrogen bonding strength, and enhanced the stability of Mn-oxo complexes, as their size increases. Attempts are made to explain these effects. A mechanistic scheme is also suggested for the decomposition of HSO5- to O2 and HSO4-, through the formation and dimerization of Mn-oxo species.

  15. Evapotranspiration of Mixed Shrub Communities in Phreatophytic Zones of the Great Basin D.A. Devitt1, L.K. Fenstermaker2, M. Young2, B. Conrad1 and B. Bird1 1 School of Life Sciences, University of Nevada Las Vegas, Las Vegas, NV 2 Desert Research Institute, Las Vegas, NV

    NASA Astrophysics Data System (ADS)

    Devitt, D. A.; Fenstermaker, L. K.; Young, M.; Conrad, B.; Bird, B.

    2009-12-01

    Water limitations in the arid and semiarid regions of the southwestern United States have led many water managers of municipalities to begin the process of diversifying their water resource portfolios. Las Vegas in particular, is pursuing groundwater exportation from east central basins in Nevada. Estimating evapotranspiration (ET) is a critical component to closing hydrologic balances in these basins. As such, ET was estimated for three valleys in the Great Basin Region of Nevada (USA) during a three year period. ET estimates were made based on an energy balance approach using the eddy covariance method. ET estimates at the basin scale were made by developing empirical relationships between ET and remotely sensed spectral data (Landsat). Groundwater, soil moisture, rainfall and leaf level measurements were used to validate the differences in ET estimates based on site, year and basin. When the ET correlations were based on average NDVI values during the growing period and incorporated previously published values attained for the same valleys during the same time period, we could account for 97% of the variation in the ET estimate for the May 10 to September 5 growing period and 93% of the variation in the ET estimates based on measured or projected yearly ET totals. Variations in yearly ET estimates at the different shrub and grassland sites ranged from 20 to 50 cm during the two dry years (2006, 2007, not including the irrigated site). The amount of winter precipitation was shown to be a significant driving force in the physiological response of the plants and the yearly ET totals. In the case of White River Valley the ratio of winter precipitation to reference evapotranspiration declined from 79% to 11% over the 3 year monitoring period. Such changes led to a direct impact on leaf xylem water potential values of greasewood (Sarcobatus vermiculatus). During the two drier years (2006 and 2007) greasewood plants entered into the growing period with lower mid day

  16. Molecular Basis for the Recognition of Structurally Distinct Autoinducer Mimics by the Pseudomonas aeruginosa LasR Quorum-Sensing Signaling Receptor

    SciTech Connect

    Zou, Yaozhong; Nair, Satish K.

    2010-01-12

    The human pathogen Pseudomonas aeruginosa coordinates the expression of virulence factors using quorum sensing, a signaling cascade triggered by the activation of signal receptors by small-molecule autoinducers. These homoserine lactone autoinducers stabilize their cognate receptors and activate their functions as transcription factors. Because quorum sensing regulates the progression of infection and host immune resistance, significant efforts have been devoted toward the identification of small molecules that disrupt this process. Screening efforts have identified a class of triphenyl compounds that are structurally distinct from the homoserine lactone autoinducer, yet interact specifically and potently with LasR receptor to modulate quorum sensing (Muh et al., 2006a). Here we present the high-resolution crystal structures of the ligand binding domain of LasR in complex with the autoinducer N-3-oxo-dodecanoyl homoserine lactone (1.4 {angstrom} resolution), and with the triphenyl mimics TP-1, TP-3, and TP-4 (to between 1.8 {angstrom} and 2.3 {angstrom} resolution). These crystal structures provide a molecular rationale for understanding how chemically distinct compounds can be accommodated by a highly selective receptor, and provide the framework for the development of novel quorum-sensing regulators, utilizing the triphenyl scaffold.

  17. High-level nuclear waste transport and storage assessment of potential impacts on tourism in the Las Vegas area. Nevada Nuclear Waste Storage Investigations Project

    SciTech Connect

    1985-12-01

    The literature review and empirical analyses presented in this report were undertaken, for the most part, between August and October 1983. They are not comprehensive. No primary data were gathered, nor were any formal surveys conducted. Additionally, because construction of a repository at Yucca Mountain, if that site is selected for a repository, is not scheduled to begin until 1993, engineering design and planned physical appearance of the repository are very preliminary. Therefore, specific design features or visual appearance were not addressed in the analyses. Finally, because actual transportation routes have not been designated, impacts on tourism generated specifically by transportation activities are not considered separately. Chapter 2 briefly discusses possible means by which a repository could impact tourism in the Las Vegas area. Chapter 3 presents a review of previous research on alternative methods for predicting the response of people to potential hazards. A review of several published studies where these methods have been applied to facilities and activities associated with radioactive materials is included in Chapter 3. Chapter 4 contains five case studies of tourism impacts associated with past events that were perceived by the public to represent safety hazards. These perceptions of safety hazards were evidenced by news media coverage. These case studies were conducted specifically for this report. Conclusions of this preliminary analysis regarding the potential impact on tourism in the Las Vegas area of a repository at Yucca Mountain are in Chapter 5. Recommendations for further research are contained in Chapter 6.

  18. Ethnobotany and antibacterial activity of some plants used in traditional medicine of Zapotitlán de las Salinas, Puebla (México).

    PubMed

    Hernández, T; Canales, M; Avila, J G; Duran, A; Caballero, J; Romo de Vivar, A; Lira, R

    2003-10-01

    The village of Zapotitlán de las Salinas is situated in the Valley of Tehuacán-Cuicatlán, Puebla, Mexico. Plant species used by the local inhabitants to treat gastrointestinal diseases were identified using ethnobotanical, ethnographic and taxonomic methods. Out of 119 interviews, 44 plant species were registered, of which the following are the most frequently used (listed in descending order): Lippia graveolens H.B. et K. (Verbenaceae), Lantana achyranthifolia Desf. (Verbenaceae), Turnera diffusa (Willd.) ex Schult. (Turneraceae), Lippia oaxacana Rob. et Greenm. (Verbenaceae), Gymnolaena oaxacana (Greenm.) Rydb. (Asteraceae), Cordia curassavica (Jacq.) Roem. et Schult. (Boraginaceae), Lantana camara L. (Verbenaceae) and Acalypha hederacea Torrey (Euphorbiaceae). From these plants, hexane, chloroform and ethanol extracts were prepared in order to assess their antibacterial activity against 14 bacterial strains causing the most common gastrointestinal diseases in Mexican population. All hexane extracts showed antibacterial activity against Gram-positive and Gram-negative bacteria. There is a correlation between the frequency of mention (of plant use) and the antibacterial activity. In conclusion, the knowledge of plants most frequently used for gastrointestinal infections in Zapotitlán de las Salinas is supported by scientific rationale. PMID:12963140

  19. Inverse steptoes in Las Bombas volcano, as an evidence of explosive volcanism in a solidified lava flow field. Southern Mendoza-Argentina

    NASA Astrophysics Data System (ADS)

    Risso, Corina; Prezzi, Claudia; Orgeira, María Julia; Nullo, Francisco; Margonari, Liliana; Németh, Karoly

    2015-11-01

    Here we describe the unusual genesis of steptoes in Las Bombas volcano- Llancanelo Volcanic Field (LVF) (Pliocene - Quaternary), Mendoza, Argentina. Typically, a steptoe forms when a lava flow envelops a hill, creating a well-defined stratigraphic relationship between the older hill and the younger lava flow. In the Llancanelo Volcanic Field, we find steptoes formed with an apparent normal stratigraphic relationship but an inverse age-relationship. Eroded remnants of scoria cones occur in "circular depressions" in the lava field. To express the inverse age-relationship between flow fields and depression-filled cones here we define this landforms as inverse steptoes. Magnetometric analysis supports this inverse age relationship, indicating reverse dipolar magnetic anomalies in the lava field and normal dipolar magnetization in the scoria cones (e.g. La Bombas). Negative Bouguer anomalies calculated for Las Bombas further support the interpretation that the scoria cones formed by secondary fracturing on already solidified basaltic lava flows. Advanced erosion and mass movements in the inner edge of the depressions created a perfectly excavated circular depression enhancing the "crater-like" architecture of the preserved landforms. Given the unusual genesis of the steptoes in LVF, we prefer the term inverse steptoe for these landforms. The term steptoe is a geomorphological name that has genetic implications, indicating an older hill and a younger lava flow. Here the relationship is reversed.

  20. Compatibility and competitiveness of a laboratory strain of Anastrepha Fraterculus (Diptera: Tephritidae) after irradiation treatment

    SciTech Connect

    Allinghi, A.; Calcagno, G.; Gomez Cendra, P.; Vilardi, J.C.; Petit-Marty, N.; Segura, D.; Cladera, J.; Vera, T.; Gramajo, C.; Willink, E.

    2007-03-15

    salvaje (TUC) de Anastrepha fraterculus (Wiedemann). La linea de laboratorio se produce en condiciones de cria semi-masiva en las instalaciones de la Estacion Experimental Agroindustrial Obispo Colombres (Tucuman, Argentina). Las moscas salvajes se obtuvieron de frutas infestadas de guayabos en Horco Molle (Tucuman, Argentina). Las pupas de laboratorio fueron irradiadas ({sup 60}Co) 48 horas antes de la emergencia del adulto. Las dosis utilizadas fueron 0 (control), 40, 70, y 100 Gy. Se liberaron 25 machos y 25 hembras de TUC y LAB dentro de las jaulas y se recolectaron las parejas formadas. Solo se considero 1 dosis de irradiacion por vez. Las hembras apareadas fueron separadas y se les permitio poner huevos en frutas artificiales para estimar la esterilidad inducida a traves del porcentaje de eclosion. La hora de inicio de la copula no difirio significativamente entre poblaciones ni entre los tratamientos de irradiacion. La duracion de la copula mostro grandes diferencias entre dosis de irradiacion pero no entre cepas. Los indices ISI (aislamiento) y el RSI (esterilidad relativa) indican que LAB y TUC son totalmente compatibles, los machos de TUC y LAB no difieren en su competitividad y la irradiacion dentro del rango de dosis utilizadas tampoco afecto este indice. Las hembras LAB no irradiadas muestran una mayor propension para el apareamiento que las hembras de TUC. Sin embargo se observo una reduccion significativa del indice FRPI (actuacion relativa de hembras) a medida que se aumenta la dosis de irradiacion. El analisis de la esterilidad inducida indica que con dosis de 40 Gy la fertilidad disminuye del 80% al 0.75%, y con dosis mayores la esterilidad fue total. Las hembras irradiadas con dosis de 40 Gy tienen una fertilidad de aproximadamente 2% y con dosis mayores no ponen huevos. (author)

  1. Estudio teórico de la desorción de Na y K de SiO2 estimulada por la acción de fotones o electrones

    NASA Astrophysics Data System (ADS)

    Domínguez Ariza, D.; López, N.; Illas, F.; Pacchioni, G.; Madey, T. E.

    Se ha estudiado el mecanismo de generación de sodio y potasio atómico a partir de muestras de SiO2 utilizando cálculos basados tanto en la teoría del funcional de la densidad como en métodos post-Hartree Fock, así como en el método de cluster para modelar el sólido. Como consecuencia del estudio se han propuesto distintos caminos posibles para la desorción, estimulada por la acción de fotones o electrones, de sodio y potasio desde el óxido de silicio, proporcionando por lo tanto una explicación a la atmósfera tenue de sodio y potasio de La Luna.

  2. Comparing the suitability of geophysical methods in the study of a cave in marbles: A case study of Gruta de las Maravillas (Aracena, Southwest Spain)

    NASA Astrophysics Data System (ADS)

    José Martínez Moreno, Francisco; Galindo Zaldívar, Jesús; Pedrera Parias, Antonio; Ullod, Teresa Teixidó i.; Ruano Roca, Patricia; Peña Ruano, Jose Antonio; González Castillo, Lourdes; Ruiz Constan, Ana; López Chicano, Manuel; Martín Rosales, Wenceslao

    2014-05-01

    Different geophysical methods have been applied to determine the geometry of caves, considering the host rock, depth, dimension, presence of water and other parameters. The Gruta de las Maravillas cave is located in marbles interlayered with gneiss, quartzite and granodiorite along the suture between South Portuguese and Ossa Morena zone. This cave is probably formed as a consequence of the presence of pyrite and iron oxides mineralization that interacted with the surrounding marble host rocks. In order to analyze the continuity of the Gruta de las Maravillas cave (Aracena, southwest Spain) geophysical methods has been used on the known cave in order to check their suitability. These results allow investigating the prolongation of the cave in surrounding areas, performing a comprehensive study of the Cerro del Castillo hill containing the cavity. Microtopography with differential GPS and cave topography with an accuracy of 0.01 m were measured. The first geophysical method employed were a regional microgravity, with and SCINTREX CG-5 gravimeter that reaches an accuracy up to 0.001 mGal. In the obtained residual anomaly map, negative values are associated with negative density contrast, which are related to the known cave position. In addition, residual gravity minima suggest the presence of other unknown cavities. The anomalies attributed to possible new shallow and deep caves have been studied in a second step with the application of other eight detailed geophysical methods along profiles to test the response of each of them to the presence of cavities: microgravity, magnetic, electrical resistivity tomography, induced polarization, seismic P-waves velocity tomography, ray tracing coverage, common offset and ground-penetrating radar. Moreover, the known cave has walls covered with iron oxides that determine magnetic anomaly minima and intermediate resistivity values (~2000 ohm.m) on the ERT profiles versus the host marble rocks (~45000 ohm.m). After a detailed

  3. Sensing the ups and downs of Las Vegas: InSAR reveals structural control of land subsidence and aquifer-system deformation

    USGS Publications Warehouse

    Amelung, F.; Galloway, D.L.; Bell, J.W.; Zebker, H.A.; Laczniak, R.J.

    1999-01-01

    Land subsidence in Las Vegas, Nevada, United States, between April 1992 and December 1997 was measured using spaceborne interferometric synthetic aperture radar. The detailed deformation maps clearly show that the spatial extent of subsidence is controlled by geologic structures (faults) and sediment composition (clay thickness). The maximum detected subsidence during the 5.75 yr period is 19 cm. Comparison with leveling data indicates that the subsidence rates declined during the past decade as a result of rising ground-water levels brought about by a net reduction in ground-water extraction. Temporal analysis also detects seasonal subsidence and uplift patterns, which provide information about the elastic and inelastic properties of the aquifer system and their spatial variability.

  4. Environmental and geochemical record of human-induced changes in C storage during the last millennium in a temperate wetland (Las Tablas de Daimiel National Park, central Spain)

    USGS Publications Warehouse

    Dominguez-Castro, F.; Santisteban, J.I.; Mediavilla, R.; Dean, W.E.; Lopez-Pamo, E.; Gil-Garcia, M. J.; Ruiz-Zapata, M. B.

    2006-01-01

    Las Tablas de Daimiel National Park has experienced many hydrological and ecological modifications through out its history, both of natural as well as anthropogenic origin, which have affected its carbon storage capacity and carbon fluxes. The study of those variations has been carried out by the analysis of its sedimentary record (geochemistry and pollen) and historical data. The natural changes have a wider variation range than the anthropogenic ones, show repetitive patterns and the system reacts readjusting the equilibrium among its components. Anthropogenic effects depend on the direct or indirect impact on the wetlands of change and its intensity. In addition, the anthropogenic impacts have the capacity of breaking the natural balance of the ecosystem and the internal interactions. ?? 2006 The Authors Journal compilation ?? 2006 Blackwell Munksgaard.

  5. The LasB Elastase of Pseudomonas aeruginosa Acts in Concert with Alkaline Protease AprA To Prevent Flagellin-Mediated Immune Recognition

    PubMed Central

    Casilag, Fiordiligie; Lorenz, Anne; Krueger, Jonas; Klawonn, Frank; Weiss, Siegfried

    2015-01-01

    The opportunistic pathogen Pseudomonas aeruginosa is capable of establishing severe and persistent infections in various eukaryotic hosts. It encodes a wide array of virulence factors and employs several strategies to evade immune detection. In the present study, we screened the Harvard Medical School transposon mutant library of P. aeruginosa PA14 for bacterial factors that modulate interleukin-8 responses in A549 human airway epithelial cells. We found that in addition to the previously identified alkaline protease AprA, the elastase LasB is capable of degrading exogenous flagellin under calcium-replete conditions and prevents flagellin-mediated immune recognition. Our results indicate that the production of two proteases with anti-flagellin activity provides a failsafe mechanism for P. aeruginosa to ensure the maintenance of protease-dependent immune-modulating functions. PMID:26502908

  6. The Tangled Branches (Las Ramas Enredadas): Sexual Risk, Substance Abuse, and Intimate Partner Violence Among Hispanic Men who Have Sex with Men

    PubMed Central

    De Santis, Joseph P.; Gonzalez-Guarda, Rosa; Provencio-Vasquez, Elias; Deleon, Diego A.

    2012-01-01

    Hispanic men who have sex with men (MSM) experience a number of health disparities including high rates of HIV infection from high risk sex, substance abuse, and intimate partner violence. Although some research is available to document the relationships of these health disparities in the literature, few studies have explored the intersection of these disparities and the factors that influence them. The purpose of this study was to explore the experiences that Hispanic MSM residing in South Florida have with high risk sex, substance abuse, and intimate partner violence. Focus groups were conducted and analyzed using grounded theory methodology until data saturation was reached (n = 20). Two core categories with subcategories emerged from the data: The Roots of Risk (Los raices del riesgo) and The Tangled Branches (Las Ramas Enredadas). The results of the study provided some important clinical implications as well as directions for future research with Hispanic MSM. PMID:24084703

  7. Postwildfire preliminary debris flow hazard assessment for the area burned by the 2011 Las Conchas Fire in north-central New Mexico

    USGS Publications Warehouse

    Tillery, Anne C.; Darr, Michael J.; Cannon, Susan H.; Michael, John A.

    2011-01-01

    The Las Conchas Fire during the summer of 2011 was the largest in recorded history for the state of New Mexico, burning 634 square kilometers in the Jemez Mountains of north-central New Mexico. The burned landscape is now at risk of damage from postwildfire erosion, such as that caused by debris flows and flash floods. This report presents a preliminary hazard assessment of the debris-flow potential from 321 basins burned by the Las Conchas Fire. A pair of empirical hazard-assessment models developed using data from recently burned basins throughout the intermountain western United States was used to estimate the probability of debris-flow occurrence and volume of debris flows at the outlets of selected drainage basins within the burned area. The models incorporate measures of burn severity, topography, soils, and storm rainfall to estimate the probability and volume of debris flows following the fire. In response to a design storm of 28.0 millimeters of rain in 30 minutes (10-year recurrence interval), the probabilities of debris flows estimated for basins burned by the Las Conchas Fire were greater than 80 percent for two-thirds (67 percent) of the modeled basins. Basins with a high (greater than 80 percent) probability of debris-flow occurrence were concentrated in tributaries to Santa Clara and Rio del Oso Canyons in the northeastern part of the burned area; some steep areas in the Valles Caldera National Preserve, Los Alamos, and Guaje Canyons in the east-central part of the burned area; tributaries to Peralta, Colle, Bland, and Cochiti canyons in the southwestern part of the burned area; and tributaries to Frijoles, Alamo, and Capulin Canyons in the southeastern part of the burned area (within Bandelier National Monument). Estimated debris-flow volumes ranged from 400 cubic meters to greater than 72,000 cubic meters. The largest volumes (greater than 40,000 cubic meters) were estimated for basins in Santa Clara, Los Alamos, and Water Canyons, and for two

  8. Sensing the ups and downs of Las Vegas: InSAR reveals structural control of land subsidence and aquifer-system deformation

    NASA Astrophysics Data System (ADS)

    Amelung, Falk; Galloway, Devin L.; Bell, John W.; Zebker, Howard A.; Laczniak, Randell J.

    1999-06-01

    Land subsidence in Las Vegas, Nevada, United States, between April 1992 and December 1997 was measured using spaceborne interferometric synthetic aperture radar. The detailed deformation maps clearly show that the spatial extent of subsidence is controlled by geologic structures (faults) and sediment composition (clay thickness). The maximum detected subsidence during the 5.75 yr period is 19 cm. Comparison with leveling data indicates that the subsidence rates declined during the past decade as a result of rising ground-water levels brought about by a net reduction in ground-water extraction. Temporal analysis also detects seasonal subsidence and uplift patterns, which provide information about the elastic and inelastic properties of the aquifer system and their spatial variability.

  9. The LasB Elastase of Pseudomonas aeruginosa Acts in Concert with Alkaline Protease AprA To Prevent Flagellin-Mediated Immune Recognition.

    PubMed

    Casilag, Fiordiligie; Lorenz, Anne; Krueger, Jonas; Klawonn, Frank; Weiss, Siegfried; Häussler, Susanne

    2016-01-01

    The opportunistic pathogen Pseudomonas aeruginosa is capable of establishing severe and persistent infections in various eukaryotic hosts. It encodes a wide array of virulence factors and employs several strategies to evade immune detection. In the present study, we screened the Harvard Medical School transposon mutant library of P. aeruginosa PA14 for bacterial factors that modulate interleukin-8 responses in A549 human airway epithelial cells. We found that in addition to the previously identified alkaline protease AprA, the elastase LasB is capable of degrading exogenous flagellin under calcium-replete conditions and prevents flagellin-mediated immune recognition. Our results indicate that the production of two proteases with anti-flagellin activity provides a failsafe mechanism for P. aeruginosa to ensure the maintenance of protease-dependent immune-modulating functions. PMID:26502908

  10. The Gruta de las Maravillas (Aracena, South-West Iberia): Setting and origin of a cave in marbles from dissolution of pyrite

    NASA Astrophysics Data System (ADS)

    Martínez-Moreno, F. J.; Pedrera, A.; Galindo-Zaldívar, J.; López-Chicano, M.; Azor, A.; Martín-Rosales, W.; Ruano, P.; Calaforra, J. M.; Hódar-Pérez, A.

    2016-01-01

    The Gruta de las Maravillas cave is located at the WNW side of the Cerro del Castillo hill in Aracena (Huelva, SW Spain). The cavity is hosted within marbles included in a strip of high-grade metamorphic rocks belonging to the so-called Aracena Massif in the southernmost Ossa-Morena Zone. The hill is made up of granodiorites, marbles, quartzites, and gneisses, with the foliation trending N110°E and dipping roughly 60-80° towards NE. The marbles appear highly deformed in ductile conditions, with isoclinal folds of different sizes, boudins, porphyroblasts with sigmoidal morphology, and left-lateral S-C shear fabrics. Close to the granodiorite contact, the marbles include a thin band of disseminated and massive pyrite, partially transformed to Fe-oxides. Analysis of the brittle deformation and the associated paleostresses indicates a NE-SW oriented maximum compression, probably related to the latest Variscan collisional tectonics (300 Ma; Late Carboniferous). The Gruta de las Maravillas is divided into three main levels (located at ~ 650, ~ 665 and ~ 685 m a.s.l.), the dissolution having progressed from top to bottom in different stages of stability of the water table. The initial dissolution phases were probably favoured by the presence of pyrite in the host rock, which, in turn, would have caused acidification of the circulating water. Favouring this hypothesis, a thin layer of Fe-oxides, locally including gypsum, covers some parts of the cave walls. The morphology and structure of the cavity result from interaction between the general NNE dipping foliation with sub-perpendicular joints, the pyrite-bearing band in the host marbles, and the descending water table.

  11. Estimates of hydraulic properties from a one-dimensional numerical model of vertical aquifer-system deformation, Lorenzi site, Las Vegas, Nevada

    USGS Publications Warehouse

    Pavelko, Michael T.

    2004-01-01

    Land subsidence related to aquifer-system compaction and ground-water withdrawals has been occurring in Las Vegas Valley, Nevada, since the 1930's, and by the late 1980's some areas in the valley had subsided more than 5 feet. Since the late 1980's, seasonal artificial-recharge programs have lessened the effects of summertime pumping on aquifer-system compaction, but the long-term trend of compaction continues in places. Since 1994, the U.S. Geological Survey has continuously monitored water-level changes in three piezometers and vertical aquifer-system deformation with a borehole extensometer at the Lorenzi site in Las Vegas, Nevada. A one-dimensional, numerical, ground-water flow model of the aquifer system below the Lorenzi site was developed for the period 1901-2000, to estimate aquitard vertical hydraulic conductivity, aquitard inelastic skeletal specific storage, and aquitard and aquifer elastic skeletal specific storage. Aquifer water-level data were used in the model as the aquifer-system stresses that controlled simulated vertical aquifer-system deformation. Nonlinear-regression methods were used to calibrate the model, utilizing estimated and measured aquifer-system deformation data to minimize a weighted least-squares objective function, and estimate optimal property values. Model results indicate that at the Lorenzi site, aquitard vertical hydraulic conductivity is 3 x 10-6 feet per day, aquitard inelastic skeletal specific storage is 4 x 10-5 per foot, aquitard elastic skeletal specific storage is 5 x 10-6 per foot, and aquifer elastic skeletal specific storage is 3 x 10-7 per foot. Regression statistics indicate that the model and data provided sufficient information to estimate the target properties, the model adequately simulated observed data, and the estimated property values are accurate and unique.

  12. Water Resources Estimation of the Biosphere Reserve "Sierra de las Minas" in Guatemala, by Using a Distributed Hydrological Model and Considering Lack of Data

    NASA Astrophysics Data System (ADS)

    Morales-de La Cruz, M.; Frances Garcia, F.

    2007-12-01

    The UNESCO Biosphere Reserve "Sierra de las Minas" is part of the Guatemalan System of Protected Areas and contains the largest cloud forests of Guatemala. Its southern slopes flow into the Motagua Valley, one of the more active zones in the country and paradoxically, the most arid and driest zone of Central America. The main objective of this work was to obtain a better estimation of the water resources coming from the southern slopes of the "Sierra de las Minas", and to have an analysis tool to better understand key hydrological processes involved on water sustainable management practices, as the environmental services initiatives on the zone. Unfortunately, the lack of data was the general framework. The selected model was the so called TETIS, which is a conceptual distributed model developed by our research group. A simple and efficient method was used for parameter maps estimation with a 100 m cell size. The model was calibrated at daily time step in the Teculután basin with 187 km2, by applying a new split-parameter structure coupled with the SCE-UA automatic optimization algorithm, in order to obtain the set of optimal correction factors of the model. For a period of medium daily precipitation within the validation period, we obtained a simulated discharge very close to the observed data (the monthly Nash and Sutcliffe model efficiency coefficient was 0.83). We present here a precipitation spatial and sensitivity analysis, and a simple approach for estimate the contribution of cloud forests to the hydrological balance. Finally, the calibration results were extrapolated to the Uyús ungaged basin to simulate its flow regime and to evaluate its water resources.

  13. U.S. Geological Survey Subsidence Interest Group Conference; proceedings of the Technical Meeting, Las Vegas, Nevada, February 14-16, 1995

    USGS Publications Warehouse

    Prince, Keith R.; Leake, Stanley A.

    1997-01-01

    Introducation to Papers: This report is a compilation of short papers that are based on oral presentations summarizing the results of recent research that were given at the third meeting of the Subsidence Interest Group held in Las Vegas, Nevada, February 14?16, 1995. The report includes case studies of land subsidence and aquifer-system deformation resulting from fluid withdrawal, geothermal development, and mine collapse. Methods for monitoring land subsidence using Global Positioning System technology for the rapid and accurate measurement of changes in land-surface altitude also are described. The current status of numerical simulation of land subsidence in the USGS is summarized, and several of the short papers deal with the development and application of new numerical techniques for simulation and quantification of aquifersystem deformation. Not all oral presentations made at the meeting are documented in this report. Several of the presentations were of ongoing research and as such, the findings were provisional in nature and were offered at the meeting to stimulate scientific discussion and debate among colleagues. The information presented in this report, although only a subset of the proceedings of the meeting in Las Vegas, should help expand the scientific basis for management decisions to mitigate or control the effects of land subsidence. The short papers describing the results of these studies provide a cross section of ongoing research in aquifer mechanics and land subsidence and also form an assessment of the current technology and 'state of the science.' The analytical and interpretive methods described in this report will be useful to scientists involved in studies of ground-water hydraulics and aquifer-system deformation.

  14. INNOVATIVE MEANS OF DEALING WITH POTENTIAL SOURCES OF GROUND WATER CONTAMINATION: PROCEEDINGS OF THE NATIONAL GROUND WATER QUALITY SYMPOSIUM (7TH) HELD AT LAS VEGAS, NEVADA ON SEPTEMBER 26-28, 1984

    EPA Science Inventory

    The Seventh National Ground Water Quality Symposium was held in Las Vegas, Nevada, on September 26-28, 1984. The symposium was dedicated to the memory of Mahdi S. Hantush (1921-1984), a pioneering scientist who specialized in the application of mathematics to solve transient grou...

  15. Proceedings of the International Association for Development of the Information Society (IADIS) International Conference on e-Learning (Las Palmas de Gran Canaria, Spain, July 21-24, 2015)

    ERIC Educational Resources Information Center

    Nunes, Miguel Baptista, Ed.; McPherson, Maggie, Ed.

    2015-01-01

    These proceedings contain the papers of the International Conference e-Learning 2015, which was organised by the International Association for Development of the Information and Society and is part of the Multi Conference on Computer Science and Information Systems (Las Palmas de Gran Canaria, Spain, July 21-24, 2015). The e-Learning 2015…

  16. PROGRAMA PARA LA VERIFICACION DE LA TECNOLOGIA AMBIENTAL - CULTIVANDO ASOCIACIONES PARA EL INCREMENTO DE LAS SELECCIONES DE TECNOLOGIAS AMBIENTALES A LOS SECTORES PUBLICO Y PRIVADO EN LOS ESTADOS UNIDOS Y EN EL EXTERIOR (EPA/600/F-97/005A)

    EPA Science Inventory

    La meta del ETV es verificar, a travs de una
    evaluacin de informacin objectiva y de calidad, las caracteristicas del desempeo de tecnologas
    comerciales ambientales. As el ETV proporciona a
    los compradores y los licenciadores potenciales una valoracin imparcial y creble d...

  17. Sky Observation with the Use of the Software Stellarium for Teaching Astronomy in Classes of Youth and Adult Education. (Spanish Title: Observación del Cielo con la Utilización del Software Stellarium en Las Clases de Educación de Jóvenes y Adultos.) Observação do Céu Aliada À Utilização do Software Stellarium no Ensino de Astronomia em Turmas de Educação de Jovens e Adultos (EJA)

    NASA Astrophysics Data System (ADS)

    Oliveira Bernardes, Adriana

    2010-12-01

    The aim of this paper is to present a project developed through a partnership between the Astronomy Club of Itaocara Marcos Pontes (CAIMP) and Jaime de Souza Queiroz College, both located in the town of Itaocara, in the Northwest Fluminense, to disseminate Astronomy in adult education (Education for Youth and Adult). Given the interdisciplinary nature of Astronomy, we have developed this work to motivate the learning of this science by students in adult education, who attend the subjects Chemistry, Physics and Biology. Initially, we conducted a research in the school to assess the prior knowledge of Astronomy class of adult education, noting that there is little knowledge of basic concepts of the discipline. With these data, we were able to elaborate several activities that would enable a greater involvement of students with this science, performing in the school a work of improvement of scientific literacy, whose activities will be presented in this article. El objetivo de este artículo es presentar los resultados de un proyecto realizado por el Club de Astronomía de Itaocara "Marcos Pontes" (CAIMP), conjuntamente con el Colegio Estatal" Jaime de Souza Queiroz", ambos de la ciudad de Itaocara (Noroeste Fluminense - RJ, Brasil), para la difusión de la Astronomía entre los estudiantes, tanto adultos como adolescentes. Teniendo en cuenta la naturaleza interdisciplinaria de la Astronomía, se determinó motivar el estudio de esta ciencia en los estudiantes adultos de nivel secundario matriculados en las asignaturas de Química, Física y Biología. Como primer paso, se investigó el grado de conocimiento sobre astronomía del estudiante. Este estudio inicial mostró niveles de conocimiento muy bajos de los conceptos básicos de esta ciencia, muchos de los cuales deberían haber sido asimilados dentro del plan curricular del curso de Física. Este estudio previo permitió determinar las actividades adecuadas para promover un mayor envolvimiento de los estudiantes

  18. Slope-apron deposition in an ordovician arc-related setting: The Vuelta de Las Tolas Member (Suri Formation), Famatina Basin, northwest Argentina

    USGS Publications Warehouse

    Mangano, M.G.; Buatois, L.A.

    1997-01-01

    The Ordovician Suri Formation is part of the infill of the Famatina Basin of northwest Argentina, which formed in an active setting along the western margin of early Paleozoic Gondwana. The lower part of this formation, the Vuelta de Las Tolas Member, records sedimentation on a slope apron formed in an intra-arc basin situated on a flooded continental arc platform. The coincidence of a thick Arenig-Llanvirn sedimentary succession and volcanic-plutonic arc rocks suggests an extensional or transtensional arc setting, and is consistent with evidence of an extensional regime within the volcanic arc in the northern Puna region. The studied stratigraphic sections consist of volcanic rocks and six sedimentary facies. The facies can be clustered into four facies associations. Association 1, composed of facies A (laminated siltstones and mudstones) and B (massive mudstones and siltstones), is interpreted to have accumulated from silty-muddy high-and low-density turbidity currents and highly fluid, silty debris flows, with subsequent reworking by bottom currents, and to a lesser extent, hemipelagic suspension in an open-slope setting. Facies association 2 is dominated by facies C (current-rippled siltstones) strata. These deposits are interpreted to record overbank sedimentation from fine-grained turbidity currents. Facies E (matrix-supported volcanic breccias) interbedded with andesitic lava units comprises facies association 3. Deposition was contemporaneous with subaqueous volcanic activity, and accumulated from cohesive debris flows in a coarse-grained wedge at the base of slope. Facies association 4 is typified by facies D (vitric fine-grained sandstones and siltstones) and F (channelized and graded volcanic conglomerates and breccias) deposits. These strata commonly display thinning-and fining-upward trends, indicating sedimentation from highly-concentrated volcaniclastic turbidity currents in a channelized system. The general characteristics of these deposits of fresh

  19. An overview of the 2013 Las Vegas Ozone Study (LVOS): Impact of stratospheric intrusions and long-range transport on surface air quality

    NASA Astrophysics Data System (ADS)

    Langford, A. O.; Senff, C. J.; Alvarez, R. J.; Brioude, J.; Cooper, O. R.; Holloway, J. S.; Lin, M. Y.; Marchbanks, R. D.; Pierce, R. B.; Sandberg, S. P.; Weickmann, A. M.; Williams, E. J.

    2015-05-01

    The 2013 Las Vegas Ozone Study (LVOS) was conducted in the late spring and early summer of 2013 to assess the seasonal contribution of stratosphere-to-troposphere transport (STT) and long-range transport to surface ozone in Clark County, Nevada and determine if these processes directly contribute to exceedances of the National Ambient Air Quality Standard (NAAQS) in this area. Secondary goals included the characterization of local ozone production, regional transport from the Los Angeles Basin, and impacts from wildfires. The LVOS measurement campaign took place at a former U.S. Air Force radar station ∼45 km northwest of Las Vegas on Angel Peak (∼2.7 km above mean sea level, asl) in the Spring Mountains. The study consisted of two extended periods (May 19-June 4 and June 22-28, 2013) with near daily 5-min averaged lidar measurements of ozone and backscatter profiles from the surface to ∼2.5 km above ground level (∼5.2 km asl), and continuous in situ measurements (May 20-June 28) of O3, CO, (1-min) and meteorological parameters (5-min) at the surface. These activities were guided by forecasts and analyses from the FLEXPART (FLEXible PARTticle) dispersion model and the Real Time Air Quality Modeling System (RAQMS), and the NOAA Geophysical Research Laboratory (NOAA GFDL) AM3 chemistry-climate model. In this paper, we describe the LVOS measurements and present an overview of the results. The combined measurements and model analyses show that STT directly contributed to each of the three O3 exceedances that occurred in Clark County during LVOS, with contributions to 8-h surface concentrations in excess of 30 ppbv on each of these days. The analyses show that long-range transport from Asia made smaller contributions (<10 ppbv) to surface O3 during two of those exceedances. The contribution of regional wildfires to surface O3 during the three LVOS exceedance events was found to be negligible, but wildfires were found to be a major factor during exceedance events

  20. Ground-water conditions in Las Vegas Valley, Clark County, Nevada; Part II, Hydrogeology and simulation of ground-water flow

    USGS Publications Warehouse

    Morgan, D.S.; Dettinger, M.D.

    1994-01-01

    Groundwater withdrawals in Las Vegas Valley, Nevada, primarily for municipal supplies, totaled more than 2.5 million acre-ft between 1912 and 1981, with a peak annual withdrawal rate of 88,000 acre-ft in 1968. Effects of heavy pumping are evident over large areas of the valley but are more pronounced near the major well fields. Secondary recharge from lawn irrigation and other sources is estimated to have totaled more than 340,000 acre-ft during 1972-81. Resulting rises in water-level in shallow, unconfined aquifers in the central and southeastern parts of the valley have caused: widespread water-logging of soils; increased groundwater discharge to Las Vegas Wash and its tributaries; and potential for degradation of water quality in deeper aquifers by accentuating downward vertical hydraulic potential in areas where shallow groundwater has high concentrations of dissolved solids and nitrate. A 3-dimensional groundwater flow model of the valley-fill aquifer system was constructed for use in evaluating possible groundwater management alternatives aimed at alleviating problems related to overdraft and water-logging while maximizing use of the groundwater resources. Natural recharge to the valley-fill aquifers is about 33,000 acre-ft/yr; in 1979, an estimated 44,000 acre-ft of secondary recharge infiltrated to the near-surface and developed-zone aquifers. Peak water use for lawn irrigation during summer results in rates of secondary recharge that may increase threefold from winter rates. Simulated rates of seepage to washes in the valley increased correspondingly from an average of 850 acre-ft/mo in winter to about 1,300 acre-ft/mo in the summer. Groundwater withdrawals by pumping totaled 620,000 acre-ft during 1972-81, and model results indicate that about 190,000 acre-ft of that total was derived from storage. Use of the model as a predictive tool was demonstrated by simulating the effects of using most municipal wells only during the peak-demand season of June 1