Sample records for nello studio della

  1. Disegno dello studio genomico, ambientale, microbiomico e metabolomico sulla celiachia: un approccio al futuro della prevenzione personalizzata della celiachia

    PubMed Central

    SERENA, GLORIA; LEONARD, MAUREEN M.; CAMHI, STEPHANIE; HUEDO-MEDINA, TANIA B.; FASANO, ALESSIO

    2017-01-01

    Riassunto Negli ultimi anni abbiamo assistito a un fiorire di novità cliniche e scientifiche sulla celiachia (CE), ma forse la novità più importante che influenzerà il futuro della ricerca e della clinica in questo campo riguarda la storia naturale della malattia. Per molti anni si è creduto che la predisposizione genetica e l’esposizione al glutine fossero necessarie e sufficienti allo sviluppo della CE. Studi recenti, però suggeriscono che la perdita di tolleranza al glutine possa apparire in qualsiasi momento della vita a seguito di altri elementi. Inoltre, diversi fattori ambientali conosciuti per il loro ruolo nell’influenzare la composizione della microflora intestinale sono anche stati considerati legati allo sviluppo della CE. Tra questi fattori sono inclusi la modalità di parto, la dieta dell’infante e l’uso di antibiotici. A tutt’oggi, nessuno studio longitudinale di ampia scala ha determinato se e come la composizione del microbioma e il suo profilo metabolomico possano influenzare la perdita di tolleranza al glutine e il successivo sviluppo della CE in soggetti geneticamente predisposti. In questo articolo descriviamo uno studio prospettico, multicentrico e longitudinale su infanti a rischio per la CE che utilizzerà diverse tecniche per approfondire il ruolo che il microbioma intestinale ha durante i primi passaggi dello sviluppo della malattia autoimmune. PMID:27362724

  2. The Art Studio: A Studio-Based Art Therapy Program.

    ERIC Educational Resources Information Center

    McGraw, Mary K.

    1995-01-01

    Describes the history and development of the Art Studio, a studio-based art therapy program in Cleveland, Ohio, and discusses specific patient needs that are uniquely addressed by the Art Studio model. The Art Studio was developed for use by medically ill and physically disabled persons, and is the result of a unique cooperative relationship…

  3. Discovering the Business Studio

    ERIC Educational Resources Information Center

    Barry, Daved; Meisiek, Stefan

    2015-01-01

    Over the past decade, numerous business schools have begun experimenting with studio-based inquiry, often drawing inspiration from professional studios used within art and design schools and from business and governmental studios used for problem-solving and innovation. Business school studios vary considerably in form, ranging from temporary…

  4. Renal vascular lesions as a marker of poor prognosis in patients with lupus nephritis. Gruppo Italiano per lo Studio della Nefrite Lupica (GISNEL).

    PubMed

    Banfi, G; Bertani, T; Boeri, V; Faraggiana, T; Mazzucco, G; Monga, G; Sacchi, G

    1991-08-01

    The frequency of renal vascular lesions (RVL) and their relevance in the progression of renal damage were evaluated by the Pathology Group of the "Gruppo Italiano per lo Studio della Nefrite Lupica" (GISNEL). Of 285 patients with lupus nephritis collected from 20 nephrology centers in Italy and classified according to World Health Organization (WHO) criteria, 79 cases (27.7%) with RVL were identified and classified as follows: (1) lupus vasculopathy (n = 27); (2) hemolytic-uremic syndrome/thrombotic thrombocytopenic purpura (HUS/TTP) malignant hypertension-like lesions (n = 24); (3) vasculitis (n = 8); (4) arterio-arteriosclerosis (n = 20). At the time of renal biopsy, patients with RVL had mean serum creatinine levels significantly higher than patients without RVL (201.8 +/- 195.9 mumol/L [2.2 +/- 2.2 mg/dL] v 108.1 +/- 108.0 mumol/L [1.2 +/- 1.2 mg/dL]; P less than 0.01). Hypertension was more frequent in patients with RVL than in those without (68.4% v 30.5%; P less than 0.01). The probability of kidney survival assessed according to the Kaplan-Meier method at 5 and 10 years was, respectively, 74.3% +/- 5.9% and 58.0% +/- 8.9% in patients with RVL, compared with 89.6% +/- 2.7% and 85.9% +/- 3.7% in patients without RVL. However, the two groups did not differ significantly as regards overall survival, the probability of survival at 5 and 10 years being 86.5% +/- 4.5% and 78.8% +/- 6.6% in patients with RVL and 92.2% +/- 2.2% and 83.3% +/- 4.4% in patients without RVL.(ABSTRACT TRUNCATED AT 250 WORDS)

  5. Evolutionary Analysis of DELLA-Associated Transcriptional Networks.

    PubMed

    Briones-Moreno, Asier; Hernández-García, Jorge; Vargas-Chávez, Carlos; Romero-Campero, Francisco J; Romero, José M; Valverde, Federico; Blázquez, Miguel A

    2017-01-01

    DELLA proteins are transcriptional regulators present in all land plants which have been shown to modulate the activity of over 100 transcription factors in Arabidopsis, involved in multiple physiological and developmental processes. It has been proposed that DELLAs transduce environmental information to pre-wired transcriptional circuits because their stability is regulated by gibberellins (GAs), whose homeostasis largely depends on environmental signals. The ability of GAs to promote DELLA degradation coincides with the origin of vascular plants, but the presence of DELLAs in other land plants poses at least two questions: what regulatory properties have DELLAs provided to the behavior of transcriptional networks in land plants, and how has the recruitment of DELLAs by GA signaling affected this regulation. To address these issues, we have constructed gene co-expression networks of four different organisms within the green lineage with different properties regarding DELLAs: Arabidopsis thaliana and Solanum lycopersicum (both with GA-regulated DELLA proteins), Physcomitrella patens (with GA-independent DELLA proteins) and Chlamydomonas reinhardtii (a green alga without DELLA), and we have examined the relative evolution of the subnetworks containing the potential DELLA-dependent transcriptomes. Network analysis indicates a relative increase in parameters associated with the degree of interconnectivity in the DELLA-associated subnetworks of land plants, with a stronger effect in species with GA-regulated DELLA proteins. These results suggest that DELLAs may have played a role in the coordination of multiple transcriptional programs along evolution, and the function of DELLAs as regulatory 'hubs' became further consolidated after their recruitment by GA signaling in higher plants.

  6. Learning Studios for Introductory Accounting

    ERIC Educational Resources Information Center

    Yourstone, Steven A.; Tepper, Robert J.

    2014-01-01

    Although originally designed for science courses, learning studios have been introduced at over 100 college campuses in a variety of disciplines. Our study focuses on the differences between classrooms designed as lecture spaces versus classrooms designed as learning studios. The impetus is the growing number of learning studios and…

  7. The Macintosh Based Design Studio.

    ERIC Educational Resources Information Center

    Earle, Daniel W., Jr.

    1988-01-01

    Describes the configuration of a workstation for a college design studio based on the Macintosh Plus microcomputer. Highlights include cost estimates, computer hardware peripherals, computer aided design software, networked studios, and potentials for new approaches to design activity in the computer based studio of the future. (Author/LRW)

  8. Collaborative Learning in Architectural Education: Benefits of Combining Conventional Studio, Virtual Design Studio and Live Projects

    ERIC Educational Resources Information Center

    Rodriguez, Carolina; Hudson, Roland; Niblock, Chantelle

    2018-01-01

    Combinations of Conventional Studio and Virtual Design Studio (VDS) have created valuable learning environments that take advantage of different instruments of communication and interaction. However, past experiences have reported limitations in regards to student engagement and motivation, especially when the studio projects encourage abstraction…

  9. The Intern Studio: A Pilot Study.

    ERIC Educational Resources Information Center

    Wix, Linney

    1995-01-01

    Describes and discusses the Intern Studio Project, which consists of the provision of regular open studio time for art therapy interns in a state university graduate program. Psychological and artistic bases for the open studio approach are discussed, and include the relational approach, Hillman's essentialist paradigm, and series and context…

  10. The "Ontopology" of the Artist's Studio as Workplace: Researching the Artist's Studio and the Art/Design Classroom

    ERIC Educational Resources Information Center

    Pigrum, Derek

    2007-01-01

    Studies in creativity most often neglect the aspect of place, of the artist's situated practices in the studio. One reason for this is that the artist's studio is one of the most difficult workplaces in which to gain entry and conduct research. This article is based on grounded research into the studio workplace of the sculptor Oswald Stimm,…

  11. Perceptions of the Students toward Studio Physics

    ERIC Educational Resources Information Center

    Gok, Tolga

    2011-01-01

    The purpose of this study was not only to report the development process of the studio model, but also to determine the students' perceptions about the studio model. This model retains the large lecture component but combines recitation and laboratory instruction into studio model. This research was based on qualitative analysis. The data of the…

  12. Studios Abroad: A Challenge in Innovative Pedagogy

    ERIC Educational Resources Information Center

    Macedo, Joseli

    2017-01-01

    Study abroad programs offer a unique opportunity to evaluate pedagogic models. The role of studios in design and planning pedagogy has been examined. However, how the general framework of a studio supports other pedagogic models has not been widely discussed. This article assesses a series of urban planning and design studios conducted abroad to…

  13. Positive Instruction in Music Studios: Introducing a New Model for Teaching Studio Music in Schools Based upon Positive Psychology.

    PubMed

    Patston, Tim; Waters, Lea

    This practice paper explores the intersection of school studio-music pedagogy and positive psychology in order to enhance students' learning and engagement. The paper has a practitioner focus and puts forward a new model of studio teaching, the Positive Instruction in Music Studios (PIMS) model that guides teachers through four key positive psychology processes that can be used in a music lesson: positive priming, strengths spotting, positive pause, and process praise. The model provides a new, positively oriented approach to studio-music pedagogy that can be integrated into specific methods-based programs to enhance student learning and engagement.

  14. Studios as Locations of Possibility: Remembering a History

    ERIC Educational Resources Information Center

    Wix, Linney

    2010-01-01

    This paper considers the studio in art therapy as a neglected yet key aspect of the field's history. Descriptions of studio art practice among the founders of the American Art Therapy Association and such predecessors as Mary Huntoon were obtained through historical research. Because both art therapy and art studios are hybrid in nature, the…

  15. DELLA genes restrict inflorescence meristem function independently of plant height.

    PubMed

    Serrano-Mislata, Antonio; Bencivenga, Stefano; Bush, Max; Schiessl, Katharina; Boden, Scott; Sablowski, Robert

    2017-09-01

    DELLA proteins associate with transcription factors to control plant growth in response to gibberellin 1 . Semi-dwarf DELLA mutants with improved harvest index and decreased lodging greatly improved global food security during the 'green revolution' in the 1960-1970s 2 . However, DELLA mutants are pleiotropic and the developmental basis for their effects on plant architecture remains poorly understood. Here, we show that DELLA proteins have genetically separable roles in controlling stem growth and the size of the inflorescence meristem, where flowers initiate. Quantitative three-dimensional image analysis, combined with a genome-wide screen for DELLA-bound loci in the inflorescence tip, revealed that DELLAs limit meristem size in Arabidopsis by directly upregulating the cell-cycle inhibitor KRP2 in the underlying rib meristem, without affecting the canonical WUSCHEL-CLAVATA meristem size regulators 3 . Mutation of KRP2 in a DELLA semi-dwarf background restored meristem size, but not stem growth, and accelerated flower production. In barley, secondary mutations in the DELLA gain-of-function mutant Sln1d 4 also uncoupled meristem and inflorescence size from plant height. Our work reveals an unexpected and conserved role for DELLA genes in controlling shoot meristem function and suggests how dissection of pleiotropic DELLA functions could unlock further yield gains in semi-dwarf mutants.

  16. DELLA proteins regulate arbuscule formation in arbuscular mycorrhizal symbiosis

    PubMed Central

    Floss, Daniela S.; Levy, Julien G.; Lévesque-Tremblay, Véronique; Pumplin, Nathan; Harrison, Maria J.

    2013-01-01

    Most flowering plants are able to form endosymbioses with arbuscular mycorrhizal fungi. In this mutualistic association, the fungus colonizes the root cortex and establishes elaborately branched hyphae, called arbuscules, within the cortical cells. Arbuscule development requires the cellular reorganization of both symbionts, and the resulting symbiotic interface functions in nutrient exchange. A plant symbiosis signaling pathway controls the development of the symbiosis. Several components of the pathway have been identified, but transcriptional regulators that control downstream pathways for arbuscule formation are still unknown. Here we show that DELLA proteins, which are repressors of gibberellic acid (GA) signaling and function at the nexus of several signaling pathways, are required for arbuscule formation. Arbuscule formation is severely impaired in a Medicago truncatula Mtdella1/Mtdella2 double mutant; GA treatment of wild-type roots phenocopies the della double mutant, and a dominant DELLA protein (della1-Δ18) enables arbuscule formation in the presence of GA. Ectopic expression of della1-Δ18 suggests that DELLA activity in the vascular tissue and endodermis is sufficient to enable arbuscule formation in the inner cortical cells. In addition, expression of della1-Δ18 restores arbuscule formation in the symbiosis signaling pathway mutant cyclops/ipd3, indicating an intersection between DELLA and symbiosis signaling for arbuscule formation. GA signaling also influences arbuscule formation in monocots, and a Green Revolution wheat variety carrying dominant DELLA alleles shows enhanced colonization but a limited growth response to arbuscular mycorrhizal symbiosis. PMID:24297892

  17. DELLA proteins regulate arbuscule formation in arbuscular mycorrhizal symbiosis.

    PubMed

    Floss, Daniela S; Levy, Julien G; Lévesque-Tremblay, Véronique; Pumplin, Nathan; Harrison, Maria J

    2013-12-17

    Most flowering plants are able to form endosymbioses with arbuscular mycorrhizal fungi. In this mutualistic association, the fungus colonizes the root cortex and establishes elaborately branched hyphae, called arbuscules, within the cortical cells. Arbuscule development requires the cellular reorganization of both symbionts, and the resulting symbiotic interface functions in nutrient exchange. A plant symbiosis signaling pathway controls the development of the symbiosis. Several components of the pathway have been identified, but transcriptional regulators that control downstream pathways for arbuscule formation are still unknown. Here we show that DELLA proteins, which are repressors of gibberellic acid (GA) signaling and function at the nexus of several signaling pathways, are required for arbuscule formation. Arbuscule formation is severely impaired in a Medicago truncatula Mtdella1/Mtdella2 double mutant; GA treatment of wild-type roots phenocopies the della double mutant, and a dominant DELLA protein (della1-Δ18) enables arbuscule formation in the presence of GA. Ectopic expression of della1-Δ18 suggests that DELLA activity in the vascular tissue and endodermis is sufficient to enable arbuscule formation in the inner cortical cells. In addition, expression of della1-Δ18 restores arbuscule formation in the symbiosis signaling pathway mutant cyclops/ipd3, indicating an intersection between DELLA and symbiosis signaling for arbuscule formation. GA signaling also influences arbuscule formation in monocots, and a Green Revolution wheat variety carrying dominant DELLA alleles shows enhanced colonization but a limited growth response to arbuscular mycorrhizal symbiosis.

  18. DELLA genes restrict inflorescence meristem function independently of plant height

    PubMed Central

    Serrano-Mislata, Antonio; Bencivenga, Stefano; Bush, Max; Schiessl, Katharina; Boden, Scott; Sablowski, Robert

    2017-01-01

    Summary DELLA proteins associate with transcription factors to control plant growth in response to gibberellin 1. Semi-dwarf DELLA mutants with improved harvest index and decreased lodging greatly improved global food security during the “green revolution” in the 1960-70s 2. However, DELLA mutants are pleiotropic and the developmental basis for their effects on plant architecture remains poorly understood. Here, we show that DELLA proteins have genetically separable roles in controlling stem growth and the size of the inflorescence meristem, where flowers initiate. Quantitative 3D image analysis, combined with a genome-wide screen for DELLA-bound loci in the inflorescence tip, revealed that DELLAs limit meristem size in Arabidopsis by directly up-regulating the cell cycle inhibitor KRP2 in the underlying rib meristem, without affecting the canonical WUSCHEL-CLAVATA meristem size regulators3. Mutation of KRP2 in a DELLA semi-dwarf background restored meristem size, but not stem growth, and accelerated flower production. In barley, secondary mutations in the DELLA gain of function mutant Sln1d 4 also uncoupled meristem and inflorescence size from plant height. Our work reveals an unexpected and conserved role for DELLA genes in controlling shoot meristem function and suggests how dissection of pleiotropic DELLA functions could unlock further yield gains in semi-dwarf mutants. PMID:28827519

  19. Designing and Maintaining the CATV and Small TV Studio.

    ERIC Educational Resources Information Center

    Knecht, Kenneth B.

    Written especially for those who want expert, indepth guidance on setting up a small-to-medium size television studio, this handbook is a detailed guide on the installation and maintenance of production facilities for cable, closed-circuit, instructional, and small broadcast television studios. Detailed discussions are included of studio pulse…

  20. Gibberellin signaling: a theme and variations on DELLA repression

    USDA-ARS?s Scientific Manuscript database

    DELLA proteolysis through the ubiquitin-proteasome pathway or through the proteolysis-independent mechanisms. GA triggers DELLA proteolysis via a series of protein-protein interactions. GA binding to the GID1 GA receptor increases the affinity of GID1 for DELLA leading to the formation of the GID1-G...

  1. A Studio Tells Its Story: Student-Teachers Learn Differently

    ERIC Educational Resources Information Center

    Leshem, Shosh

    2016-01-01

    The paper presents the story of an experimental learning studio in a teacher education programme at a college in Israel. The study investigates what students found significant in the studio and more specifically, the meanings students attributed to the experiences in the studio and how it constituted a site for learning. Open ended questionnaires…

  2. Chronicling a successful secondary implementation of Studio Physics

    NASA Astrophysics Data System (ADS)

    Kohl, Patrick B.; Vincent Kuo, H.

    2012-09-01

    The Colorado School of Mines (CSM) has taught its first-semester calculus-based introductory physics course (Physics I) using a hybrid lecture/Studio Physics format since the spring of 1997. Starting in the fall of 2007, we have been converting the second semester of our calculus-based introductory physics course (Physics II) to a hybrid lecture/Studio Physics format, beginning from a traditional lecture/lab/recitation course. In this paper, we document the stages of this transformation, highlighting what has worked and what has not, and the challenges and benefits associated with the switch to Studio Physics. A major goal in this study is to develop a method for secondary implementations of Studio physics that keeps the time and resource investments manageable. We describe the history of Studio at CSM and characterize our progress via several metrics, including pre/post Conceptual Survey of Electricity and Magnetism (CSEM) scores, Colorado Learning About Science Survey scores (CLASS), exam scores, failure rates, and a variety of qualitative observations. Results suggest that Studio has increased student performance and satisfaction despite an aggressive expansion of class sizes in the past few years. Gains have been concentrated mostly in problem-solving skills and exam performance (as opposed to conceptual survey gains), in contrast to what has sometimes been seen in other studies.

  3. Analysis of facility needs level in architecture studio for students’ studio grades

    NASA Astrophysics Data System (ADS)

    Lubis, A. S.; Hamid, B.; Pane, I. F.; Marpaung, B. O. Y.

    2018-03-01

    Architects must be able to play an active role and contribute to the realization of a sustainable environment. Architectural education has inherited many education research used qualitative and quantitative methods. The data were gathered by conducting (a) observation,(b) interviews, (c) documentation, (d) literature study, and (e) Questionnaire. The gathered data were analyzed qualitatively to find out what equipment needed in the learning process in the Architecture Studio, USU. Questionnaires and Ms. Excel were used for the quantitative analysis. The tabulation of quantitative data would be correlated with the students’ studio grades. The result of the research showed that equipment with the highest level of needs was (1) drawing table, (2) Special room for each student, (3) Internet Network, (4) Air Conditioning, (5) Sufficient lighting.

  4. Assessment of the Effectiveness of the Studio Format in Introductory Undergraduate Biology

    PubMed Central

    Rintoul, David A.; Williams, Larry G.

    2008-01-01

    Kansas State University converted its introductory biology course, previously taught as an audio-tutorial (A-T), to a studio format in 1997. We share with others information about the process involved and present assessment data for the studio format course that address 1) student exam performance in A-T and studio; 2) student course grades in A-T and studio; 3) student and instructor perceptions and attitudes for A-T and studio; 4) student performance in subsequent biology courses for A-T and studio; and 5) gains in student learning for the studio course and other traditional lecture/lab courses. Collectively, these measures demonstrate that the studio format is as effective as or more effective (for some measures) than the A-T approach and traditional approaches in providing an effective learning environment. We discuss the issues involved in comparing course formats. PMID:18519615

  5. A Framework for Daylighting Optimization in Whole Buildings with OpenStudio

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2016-08-12

    We present a toolkit and workflow for leveraging the OpenStudio (Guglielmetti et al. 2010) platform to perform daylighting analysis and optimization in a whole building energy modeling (BEM) context. We have re-implemented OpenStudio's integrated Radiance and EnergyPlus functionality as an OpenStudio Measure. The OpenStudio Radiance Measure works within the OpenStudio Application and Parametric Analysis Tool, as well as the OpenStudio Server large scale analysis framework, allowing a rigorous daylighting simulation to be performed on a single building model or potentially an entire population of programmatically generated models. The Radiance simulation results can automatically inform the broader building energy model, andmore » provide dynamic daylight metrics as a basis for decision. Through introduction and example, this paper illustrates the utility of the OpenStudio building energy modeling platform to leverage existing simulation tools for integrated building energy performance simulation, daylighting analysis, and reportage.« less

  6. Clinical and Translational Research Studios: A Multidisciplinary Internal Support Program

    PubMed Central

    Byrne, Daniel W.; Biaggioni, Italo; Bernard, Gordon R.; Helmer, Tara T.; Boone, Leslie R.; Pulley, Jill M.; Edwards, Terri; Dittus, Robert S.

    2012-01-01

    The Vanderbilt Institute for Clinical and Translational Research implemented the “Studio” Program in 2007 to bring together experts to provide free, structured, project-specific feedback for medical researchers. Studios are a series of integrated, dynamic, and interactive roundtable discussions that bring relevant research experts from diverse academic disciplines together to focus on a specific research project at a specific stage. Vanderbilt’s Clinical and Translational Science Award supports the program, which is designed to improve the quality and impact of biomedical research. In this article, the authors describe the program’s design, and they provide an evaluation of its first four years. After an investigator completes a brief online studio application, a studio “manager” reviews the request, assembles a panel of 3 to 6 experts (research faculty from multiple disciplines), and circulates the pre-review materials electronically. Investigators can request one of seven studio formats: hypothesis generation, study design, grant review, implementation, analysis and interpretation, manuscript review, or translation. A studio moderator leads each studio session, managing the time (90 minutes) and discussion to optimize the usefulness of the session for the investigator. Feedback from the 157 studio sessions in the first four years has been overwhelmingly positive. Investigators have indicated that their studios have improved the quality of their science (99%; 121/122 responses), and experts have reported that the studios have been a valuable use of their time (98%; 398/406 responses). To achieve the health goals of the 21st century, researchers from multiple disciplines must bridge their differences and together address the challenging problems that face us. -- The Institute of Medicine, 20011 PMID:22722360

  7. The gibberellin GID1-DELLA signalling module exists in evolutionarily ancient conifers.

    PubMed

    Du, Ran; Niu, Shihui; Liu, Yang; Sun, Xinrui; Porth, Ilga; El-Kassaby, Yousry A; Li, Wei

    2017-11-30

    Gibberellins (GAs) participate in controlling various aspects of basic plant growth responses. With the exception of bryophytes, GA signalling in land plants, such as lycophytes, ferns and angiosperms, is mediated via GIBBERELLIN-INSENSITIVE DWARF1 (GID1) and DELLA proteins. To explore whether this GID1-DELLA mechanism is present in pines, we cloned an orthologue (PtGID1) of Arabidopsis AtGID1a and two putative DELLA proteins (PtDPL; PtRGA) from Pinus tabuliformis, a widespread indigenous conifer species in China, and studied their recombinant proteins. PtGID1 shares with AtGID1a the conserved HSL motifs for GA binding and an N-terminal feature that are essential for interaction with DELLA proteins. Indeed, A. thaliana 35S:PtGID1 overexpressors showed a strong GA-hypersensitive phenotype compared to the wild type. Interactions between PtGID1 and PtDELLAs, but also interactions between the conifer-angiosperm counterparts (i.e. between AtGID1 and PtDELLAs and between PtGID1 and AtDELLA), were detected in vivo. This demonstrates that pine has functional GID1-DELLA components. The Δ17-domains within PtDPL and PtRGA were identified as potential interaction sites within PtDELLAs. Our results show that PtGID1 has the ability to interact with DELLA and functions as a GA receptor. Thus, a GA-GID1-DELLA signalling module also operates in evolutionarily ancient conifers.

  8. A Guide for Prospective Piano Studio Teachers

    ERIC Educational Resources Information Center

    Wei, Erh-Chia

    2010-01-01

    Many music majors choose to become studio teachers upon graduation from university. But, few realize the difficulties involved in setting up a private studio. What seems to be an easy job at the beginning actually involves many diverse skills that need to be learned, skills that are all too often not part of a university education. Teaching is…

  9. Course Design Using an Authentic Studio Model

    ERIC Educational Resources Information Center

    Wilson, Jay R.

    2013-01-01

    Educational Technology and Design 879 is a graduate course that introduces students to the basics of video design and production. In an attempt to improve the learning experience for students a redesign of the course was implemented for the summer of 2011 that incorporated an authentic design studio model. The design studio approach is based on…

  10. Studio-based learning in interprofessional education.

    PubMed

    Shraiky, James Rodolfo; Lamb, Gerri

    2013-11-01

    The recent growth of interprofessional education (IPE) in healthcare has been accompanied by exploration of teaching strategies to improve its effectiveness. Experts in IPE advise faculty to explore teaching models from other disciplines outside of healthcare. Studio-based learning (SBL) in design education embodies many of the features that are integral to effective IPE. Students work in teams to design new processes and products to solve complex and real-life problems. The purpose of this paper is to describe features of SBL that enhance IPE and examine student experiences of interprofessional learning from three healthcare design studios. Findings from an exploratory case study of these design studios involving students from a range of professions suggest that the students transition through learning stages in SBL that may enhance IPE. The paper goes on to discuss the unique features of SBL and how they offer new and complementary strategies for building interprofessional curricula.

  11. Home studio acoustic treatments on a budget

    NASA Astrophysics Data System (ADS)

    Haverstick, Gavin A.

    2003-04-01

    Digital technology in the recording industry has evolved and expanded, allowing it to be widely available to the public at a significantly lower cost than in previous years. Due to this fact, numerous home studios are either being built inside or converted from bedrooms, dens, and basements. Hobbyists and part-time musicians that typically do not have the advantage of a large recording budget operate the majority of these home studios. Along with digital equipment, acoustic treatment has become more affordable over the years giving many musicians the ability to write, record, and produce an entire album in the comfort of their own home without having to sacrifice acoustical quality along the way. Three separate case studies were conducted on rooms with various sizes, applications, and budgets. Acoustical treatment such as absorption, diffusion, and bass trapping were implemented to reduce the effects of issues such as flutter echo, excessive reverberation, and bass build-up among others. Reactions and subjective comments from each individual studio owner were gathered and assessed to determine how effective home studios can be on a personal and professional level if accurately treated acoustically.

  12. Lifting DELLA repression of Arabidopsis seed germination by nonproteolytic gibberellin signaling

    USDA-ARS?s Scientific Manuscript database

    DELLA repression of Arabidopsis seed germination can be lifted through the ubiquitin-proteasome pathway and proteolysis-independent GA signaling. GA-binding to the GID1 (GIBBERELLIN-INSENSITIVE DWARF1) GA receptors stimulates GID1-GA-DELLA complex formation which in turn triggers DELLA protein ubiq...

  13. NREL's OpenStudio Helps Design More Efficient Buildings (Fact Sheet)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    2014-07-01

    The National Renewable Energy Laboratory (NREL) has created the OpenStudio software platform that makes it easier for architects and engineers to evaluate building energy efficiency measures throughout the design process. OpenStudio makes energy modeling more accessible and affordable, helping professionals to design structures with lower utility bills and less carbon emissions, resulting in a healthier environment. OpenStudio includes a user-friendly application suite that makes the U.S. Department of Energy's EnergyPlus and Radiance simulation engines easier to use for whole building energy and daylighting performance analysis. OpenStudio is freely available and runs on Windows, Mac, and Linux operating systems.

  14. An unusual spliced variant of DELLA protein, a negative regulator of gibberellin signaling, in lettuce.

    PubMed

    Sawada, Yoshiaki; Umetsu, Asami; Komatsu, Yuki; Kitamura, Jun; Suzuki, Hiroyuki; Asami, Tadao; Fukuda, Machiko; Honda, Ichiro; Mitsuhashi, Wataru; Nakajima, Masatoshi; Toyomasu, Tomonobu

    2012-01-01

    DELLA proteins are negative regulators of the signaling of gibberellin (GA), a phytohormone regulating plant growth. DELLA degradation is triggered by its interaction with GID1, a soluble GA receptor, in the presence of bioactive GA. We isolated cDNA from a spliced variant of LsDELLA1 mRNA in lettuce, and named it LsDELLA1sv. It was deduced that LsDELLA1sv encodes truncated LsDELLA1, which has DELLA and VHYNP motifs at the N terminus but lacks part of the C-terminal GRAS domain. The recombinant LsDELLA1sv protein interacted with both Arabidopsis GID1 and lettuce GID1s in the presence of GA. A yeast two-hybrid assay suggested that LsDELLA1sv interacted with LsDELLA1. The ratio of LsDELLA1sv to LsDELLA1 transcripts was higher in flower samples at the late reproductive stage and seed samples (dry seeds and imbibed seeds) than in the other organ samples examined. This study suggests that LsDELLA1sv is a possible modulator of GA signaling in lettuce.

  15. An Examination of Student Outcomes in Studio Chemistry

    ERIC Educational Resources Information Center

    Kiste, Alan L.; Scott, Gregory E.; Bukenberger, Jesse; Markmann, Miles; Moore, Jennifer

    2017-01-01

    Twenty years ago, a major curriculum revision at a large, comprehensive university in the Western United States led to the implementation of an integrated lecture/laboratory (studio) experience for our engineering students taking general chemistry. Based on these twenty years of experience, construction of four purpose-built studio classrooms to…

  16. Constructions of Roles in Studio Teaching and Learning

    ERIC Educational Resources Information Center

    Belluigi, Dina Zoe

    2016-01-01

    Various constructions of supervisors and students emerge from education literature on art, design and architecture studio pedagogy. Constructions of the supervisor within the studio and during assessment are considered, with a discussion of the threads which underpin them. This is followed by a discussion of some of the current dominant…

  17. 47 CFR 73.1125 - Station main studio location.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Station main studio location. 73.1125 Section... RADIO BROADCAST SERVICES Rules Applicable to All Broadcast Stations § 73.1125 Station main studio location. (a) Except for those stations described in paragraph (b) of this section, each AM, FM, and TV...

  18. 47 CFR 73.1125 - Station main studio location.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Station main studio location. 73.1125 Section... RADIO BROADCAST SERVICES Rules Applicable to All Broadcast Stations § 73.1125 Station main studio location. (a) Except for those stations described in paragraph (b) of this section, each AM, FM, and TV...

  19. 47 CFR 73.1125 - Station main studio location.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false Station main studio location. 73.1125 Section... RADIO BROADCAST SERVICES Rules Applicable to All Broadcast Stations § 73.1125 Station main studio location. (a) Except for those stations described in paragraph (b) of this section, each AM, FM, and TV...

  20. 47 CFR 73.1125 - Station main studio location.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false Station main studio location. 73.1125 Section... RADIO BROADCAST SERVICES Rules Applicable to All Broadcast Stations § 73.1125 Station main studio location. (a) Except for those stations described in paragraph (b) of this section, each AM, FM, and TV...

  1. Design Studios in Instructional Design and Technology: What Are the Possibilities?

    ERIC Educational Resources Information Center

    Knowlton, Dave S.

    2016-01-01

    Design studios are an innovative way to educate Instructional Design and Technology (IDT) students. This article begins by addressing literature about IDT design studios. One conclusion from this literature is that IDT studios have been theoretically conceptualized. However, much of this conceptualization is insular to the field of IDT and only…

  2. Using Reflective Journals in a Sustainable Design Studio

    ERIC Educational Resources Information Center

    Gulwadi, Gowri Betrabet

    2009-01-01

    Purpose: This paper seeks to introduce a pedagogical method used in a design studio as part of a curriculum-greening process to encourage reflection on the complexity of sustainability and sustainable design. Online reflective journals were used in two semesters of a sustainable design studio to develop students' awareness and understanding of…

  3. Using Reflective Journals in a Sustainable Design Studio

    ERIC Educational Resources Information Center

    Gulwadi, Gowri Betrabet

    2009-01-01

    Purpose: The purpose of this paper is to introduce a pedagogical method used in a design studio as part of a curriculum-greening process to encourage reflection on the complexity of sustainability and sustainable design. Online reflective journals were used in two semesters of a sustainable design studio to develop students' awareness and…

  4. Keeping the Studio.

    ERIC Educational Resources Information Center

    McNiff, Shaun

    1995-01-01

    Discusses the studio as a therapeutic community of images where the therapist functions as keeper of the space. It is not the physical suitability that determines the suitability of the space; rather, distractions and imperfections in the space may more accurately mirror the state of psyche and so induce the passionate engagement that calls forth…

  5. (Relatively) Painless Computer-Assisted Instruction with HyperStudio.

    ERIC Educational Resources Information Center

    Pina, Anthony A.

    The College of the Desert (California) has created a multi-station technology training and development facility for faculty. HyperStudio has been adopted as the introductory tool for multimedia/hypermedia authoring for the following reasons: (1) the card/stack metaphor used by HyperStudio is easy for novices to understand and familiar to users of…

  6. A Cross-Cultural and Interdisciplinary Collaboration in a Joint Design Studio

    ERIC Educational Resources Information Center

    Kim, Mi Jeong; Ju, Seo Ryeung; Lee, Lina

    2015-01-01

    A design studio is a critical venue for design students, as they are educated to develop design thinking and other skills through studio courses. This article introduces a design studio project in which Korean and Malaysian students worked jointly for one semester to design affordable urban housing. The Korean students were interior design majors…

  7. The National Standards for Music Education: A Transdisciplinary Approach in the Applied Studio

    ERIC Educational Resources Information Center

    Frederickson, Matthew L.

    2010-01-01

    The opportunity for individualized instruction in the college studio allows the studio teacher to be a strong influence on the development of music students. The private studio can be an arena for standards implementation, bringing all aspects of a comprehensive music education to fruition. The college studio teacher is often the only teacher who…

  8. Redesigning the Urban Design Studio: Two Learning Experiments

    ERIC Educational Resources Information Center

    Pak, Burak; Verbeke, Johan

    2013-01-01

    The main aim of this paper is to discuss how the combination of Web 2.0, social media and geographic technologies can provide opportunities for learning and new forms of participation in an urban design studio. This discussion is mainly based on our recent findings from two experimental urban design studio setups as well as former research and…

  9. DELLA proteins modulate Arabidopsis defences induced in response to caterpillar herbivory

    PubMed Central

    Bede, Jacqueline C.

    2014-01-01

    Upon insect herbivory, many plant species change the direction of metabolic flux from growth into defence. Two key pathways modulating these processes are the gibberellin (GA)/DELLA pathway and the jasmonate pathway. In this study, the effect of caterpillar herbivory on plant-induced responses was compared between wild-type Arabidopsis thaliana (L.) Heynh. and quad-della mutants that have constitutively elevated GA responses. The labial saliva (LS) of caterpillars of the beet armyworm, Spodoptera exigua, is known to influence induced plant defence responses. To determine the role of this herbivore cue in determining metabolic shifts, plants were subject to herbivory by caterpillars with intact or impaired LS secretions. In both wild-type and quad-della plants, a jasmonate burst is an early response to caterpillar herbivory. Negative growth regulator DELLA proteins are required for the LS-mediated suppression of hormone levels. Jasmonate-dependent marker genes are induced in response to herbivory independently of LS, with the exception of AtPDF1.2 that showed LS-dependent expression in the quad-della mutant. Early expression of the salicylic acid (SA)-marker gene, AtPR1, was not affected by herbivory which also reflected SA hormone levels; however, this gene showed LS-dependent expression in the quad-della mutant. DELLA proteins may positively regulate glucosinolate levels and suppress laccase-like multicopper oxidase activity in response to herbivory. The present results show a link between DELLA proteins and early, induced plant defences in response to insect herbivory; in particular, these proteins are necessary for caterpillar LS-associated attenuation of defence hormones. PMID:24399173

  10. Commentary on Community-Based Art Studios: Underlying Principles

    ERIC Educational Resources Information Center

    Allen, Pat B.

    2008-01-01

    In this commentary, the author discusses the Open Studio Project, which he cofounded in 1995. The community studio, as perceived by the founders, is a place where anything can be expressed as a moment on life's continuum. Believing that meaning in art is renewed in the process of art itself, the project is not conceived at art therapy: there are…

  11. Uncovering DELLA-Independent Gibberellin Responses by Characterizing New Tomato procera Mutants

    PubMed Central

    Livne, Sivan; Lor, Vai S.; Nir, Ido; Eliaz, Natanella; Aharoni, Asaph; Olszewski, Neil E.; Eshed, Yuval; Weiss, David

    2015-01-01

    Gibberellin (GA) regulates plant development primarily by triggering the degradation/deactivation of the DELLA proteins. However, it remains unclear whether all GA responses are regulated by DELLAs. Tomato (Solanum lycopersicum) has a single DELLA gene named PROCERA (PRO), and its recessive pro allele exhibits constitutive GA activity but retains responsiveness to external GA. In the loss-of-function mutant proΔGRAS, all examined GA developmental responses were considerably enhanced relative to pro and a defect in seed desiccation tolerance was uncovered. As pro, but not proΔGRAS, elongation was promoted by GA treatment, pro may retain residual DELLA activity. In agreement with homeostatic feedback regulation of the GA biosynthetic pathway, we found that GA20oxidase1 expression was suppressed in proΔGRAS and was not affected by exogenous GA3. In contrast, expression of GA2oxidase4 was not affected by the elevated GA signaling in proΔGRAS but was strongly induced by exogenous GA3. Since a similar response was found in Arabidopsis thaliana plants with impaired activity of all five DELLA genes, we suggest that homeostatic GA responses are regulated by both DELLA-dependent and -independent pathways. Transcriptome analysis of GA-treated proΔGRAS leaves suggests that 5% of all GA-regulated genes in tomato are DELLA independent. PMID:26036254

  12. Daylight strategies for architectural studio facilities: the literature review

    NASA Astrophysics Data System (ADS)

    Othman, Muhammad Anas Bin; Azfahani Ahmad, Nur; Ajis, Azizah Md

    2017-05-01

    The implementation of daylighting strategies in buildings is a common aspect in architecture. However, due to the availability of inexpensive electricity, natural lighting strategies became insignificant, and been overlooked by designers. With the current concern over rapid increment on electricity cost, many designers now try to revitalized daylighting strategies in buildings. This includes educational buildings. In Malaysian cases, it is a norm that universities; especially during lecture and studio sessions, used artificial lighting throughout the day. Definitely, this is not parallel with the “green” aim made by the Government in the Malaysian Plan. Therefore, this paper aims to explore the impact of daylight strategies for educational studios in universities, by maximising the penetration of natural daylight into the space towards creating a more green-conducive studio. The paper review literature about the types, criteria and benefits of daylight strategies. This paper also presented a pilot study that has been performed in one university in Perak, Malaysia, by selecting architectural studios as the main subject.

  13. Leveraging OpenStudio's Application Programming Interfaces: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Long, N.; Ball, B.; Goldwasser, D.

    2013-11-01

    OpenStudio development efforts have been focused on providing Application Programming Interfaces (APIs) where users are able to extend OpenStudio without the need to compile the open source libraries. This paper will discuss the basic purposes and functionalities of the core libraries that have been wrapped with APIs including the Building Model, Results Processing, Advanced Analysis, UncertaintyQuantification, and Data Interoperability through Translators. Several building energy modeling applications have been produced using OpenStudio's API and Software Development Kits (SDK) including the United States Department of Energy's Asset ScoreCalculator, a mobile-based audit tool, an energy design assistance reporting protocol, and a portfolio scalemore » incentive optimization analysismethodology. Each of these software applications will be discussed briefly and will describe how the APIs were leveraged for various uses including high-level modeling, data transformations from detailed building audits, error checking/quality assurance of models, and use of high-performance computing for mass simulations.« less

  14. Not Just Anywhere, Anywhen: Mapping Change through Studio Work

    ERIC Educational Resources Information Center

    Tassoni, John Paul; Lewiecki-Wilson, Cynthia

    2005-01-01

    In this autoethnographic, institutional narrative, we describe the evolution of a Studio program at an open-access, regional campus of a state university. The Studio, first conceptualized by Grego and Thompson, is a one-credit writing workshop taken by students concurrently enrolled in a composition course. Developing this program necessitated…

  15. Leading institutional change: Implementing Studio in physics and beyond

    NASA Astrophysics Data System (ADS)

    Kohl, Patrick; Kuo, H. Vincent

    2013-04-01

    The Colorado School of Mines (CSM) teaches its first-year calculus-based introductory physics courses (Physics I and Physics II) using a hybrid of lecture and Studio physics. This model was first implemented in Physics I in 1997, and was established in Physics II in the fall of 2007. In this talk, we highlight the stages of the transformation from traditional to Studio, highlighting what has worked and what has not, and describing methods for assessment and evaluation. Results suggest that Studio has increased student performance and satisfaction despite an aggressive expansion of class sizes in the past few years. Gains have been concentrated mostly in problem-solving skills and exam performance (as opposed to conceptual survey gains), in contrast to what has sometimes been seen in other studies. Most recently, we as a department have been capitalizing on our successes with Studio physics to take a leadership role in disseminating advanced educational methods throughout CSM, both vertically (into upper division physics courses) and horizontally (into various departments outside of physics). We will briefly describe progress so far.

  16. Lifting DELLA Repression of Arabidopsis Seed Germination by Nonproteolytic Gibberellin Signaling1[C][W][OPEN

    PubMed Central

    Ariizumi, Tohru; Hauvermale, Amber L.; Nelson, Sven K.; Hanada, Atsushi; Yamaguchi, Shinjiro; Steber, Camille M.

    2013-01-01

    DELLA repression of Arabidopsis (Arabidopsis thaliana) seed germination can be lifted either through DELLA proteolysis by the ubiquitin-proteasome pathway or through proteolysis-independent gibberellin (GA) hormone signaling. GA binding to the GIBBERELLIN-INSENSITIVE DWARF1 (GID1) GA receptors stimulates GID1-GA-DELLA complex formation, which in turn triggers DELLA protein ubiquitination and proteolysis via the SCFSLY1 E3 ubiquitin ligase and 26S proteasome. Although DELLA cannot be destroyed in the sleepy1-2 (sly1-2) F-box mutant, long dry after-ripening and GID1 overexpression can relieve the strong sly1-2 seed dormancy phenotype. It appears that sly1-2 seed dormancy results from abscisic acid (ABA) signaling downstream of DELLA, since dormant sly1-2 seeds accumulate high levels of ABA hormone and loss of ABA sensitivity rescues sly1-2 seed germination. DELLA positively regulates the expression of XERICO, an inducer of ABA biosynthesis. GID1b overexpression rescues sly1-2 germination through proteolysis-independent DELLA down-regulation associated with increased expression of GA-inducible genes and decreased ABA accumulation, apparently as a result of decreased XERICO messenger RNA levels. Higher levels of GID1 overexpression are associated with more efficient sly1 germination and increased GID1-GA-DELLA complex formation, suggesting that GID1 down-regulates DELLA through protein binding. After-ripening results in increased GA accumulation and GID1a-dependent GA signaling, suggesting that after-ripening triggers GA-stimulated GID1-GA-DELLA protein complex formation, which in turn blocks DELLA transcriptional activation of the XERICO inhibitor of seed germination. PMID:23818171

  17. Photographic copy of October 20, 1933, black and white studio ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of October 20, 1933, black and white studio panoramic view. Located in folder 3 of 3 in box 15 of 94 at the National Museum of American History, Smithsonian Institution, Archives Center, Work and Industry Division, Washington, D.C., Charles L. Frank, Photographer, The Billings Studio. STUDIO PANORAMIC VIEW PART TWO OF TWO OF ENTIRE BRIDGE PIERS UNDER CONSTRUCTION LOOKING DOWN STREAM FROM EAST BANK ON LEFT TOWARD WEST BANK ON RIGHT. - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA

  18. Photographic copy of October 20, 1933, black and white studio ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of October 20, 1933, black and white studio panoramic view. Located in folder 3 of 3 in box 15 of 94 at the National Museum of American History, Smithsonian Institution, Archives Center, Work and Industry Division, Washington, D.C., Charles L. Frank, Photographer, The Billings Studio. OCTOBER 20, STUDIO PANORAMIC VIEW PART ONE OF TWO OF ENTIRE BRIDGE PIERS UNDER CONSTRUCTION LOOKING DOWN STREAM FROM EAST BANK ON LEFT TOWARD WEST BANK ON RIGHT. - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA

  19. The Pedagogy of the Observed: How Does Surveillance Technology Influence Dance Studio Education?

    ERIC Educational Resources Information Center

    Berg, Tanya

    2015-01-01

    A local trend in commercial dance studio education is the implementation of real-time digital video surveillance. This case study explores how digital video cameras in the dance studio environment affect asymmetrical power relationships already present in the commercial studio setting, as well as how surveillance impacts feminist pedagogical…

  20. Developing a Model for ePortfolio Design: A Studio Approach

    ERIC Educational Resources Information Center

    Carpenter, Russell; Apostel, Shawn; Hyndman, June Overton

    2012-01-01

    After developing and testing a model for integrative collaboration at Eastern Kentucky University's Noel Studio for Academic Creativity, we offer results that highlight the potential for peer review to significantly and positively impact the ePortfolio design process for students. The results of this classroom/studio collaboration suggest that…

  1. Assessment Focus in Studio: What Is Most Prominent in Architecture, Art and Design?

    ERIC Educational Resources Information Center

    de La Harpe, Barbara; Peterson, J. Fiona; Frankham, Noel; Zehner, Robert; Neale, Douglas; Musgrave, Elizabeth; McDermott, Ruth

    2009-01-01

    What can be learned about assessment from what educators in the creative practices focus their studio publications on? What should form the focus of assessment in architecture, art and design studios? In this article we draw on 118 journal articles on studio published over the last decade in three disciplines; architecture, art and design to…

  2. Student Response to an Internet-Mediated Industrial Design Studio Course

    ERIC Educational Resources Information Center

    Chen, Wenzhi; You, Manlai

    2010-01-01

    The purpose of this study is to investigate student attitudes towards and perceptions of using the Internet and information technology to mediate a design studio course and to propose guidelines and suggestions for developing Internet-mediated design studio courses. Two classes of third-year undergraduate industrial design students in two…

  3. Experiences of Teacher Reflection: Reggio Inspired Practices in the Studio

    ERIC Educational Resources Information Center

    Parnell, Will

    2012-01-01

    A teacher educator phenomenologically researches with two studio teachers, creating a dynamic of three reflective practitioners making meaning of their time in the studios. They are reflective practitioners as they claim to practice learning and teaching in reflection, action and reflective action. In their team of three, they explore the…

  4. Strategies to Assess Studio Spaces Designed to Enhance Student Learning

    ERIC Educational Resources Information Center

    Ahmadi, Reza; Saiki, Diana

    2017-01-01

    Teachers are not always aware of how the classroom design influences teaching, particularly in many family and consumer sciences (FCS) classes that require studio space, such as apparel and interior design classes. The purpose of this paper is to introduce strategies to assess studio spaces that are designed for enhancement of student learning.…

  5. Presence of Staphylococcus aureus on university dance studio floors and barres: a preliminary investigation.

    PubMed

    Unsworth, Desiree A; Russell, Jeffrey A; Martiny, Adam C

    2014-01-01

    Staphylococcus aureus (S. aureus) is a bacterium associated with various infectious diseases. Not only has the bacterium been detected in sports environments, the reported incidences of S. aureus infections have steadily increased in athletic teams. However, in spite of similarities between sports and dance facilities, to our knowledge no previous study has examined the presence of this bacterium in the dance environment. We hypothesized that S. aureus would be present in a university's dance studios, and that it would be extant in higher concentrations inside versus outside the studios. Using common microbiological culturing methods, samples were gathered from floors and barres in three studios of a single university, as well as from outside floors and railings near the studios and a conference room used by dancers. Confirming our hypothesis, we detected S. aureus in every dance studio sample (0.03 to 0.38 cfu/cm 2 ). Supporting our second hypothesis, we found that average S. aureus concentrations from the three studios were significantly higher compared to both outside and conference room samples (P ≤ 0.001). The latter two locations did not yield any S. aureus concentrations. Control samples developed as expected. The results of this study suggest that S. aureus bacteria are common on the flooring and barres of university dance studios, with the bacterial concentrations possibly dependent on the hours of usage of these surfaces. Whether the presence of S. aureus in dance studios presents a health risk to dancers should be studied further.

  6. An Investigation into the Efficacy of the Studio Model at the High School Level

    ERIC Educational Resources Information Center

    Faro, Salvatore; Swan, Karen

    2006-01-01

    The Studio Model was developed at Rensselaer Polytechnic Institute (RPI) to improve teaching and learning in introductory science classes. The study reported in this article explored the efficacy of the Studio Model at the high school level. The Studio Model combines collaborative learning with the use of online materials designed to support and…

  7. Assessing the Effectiveness of Studio Physics in Introductory-Level Courses at Georgia State University

    NASA Astrophysics Data System (ADS)

    Upton, Brianna; Evans, John; Morrow, Cherilynn; Thoms, Brian

    2009-11-01

    Previous studies have shown that many students have misconceptions about basic concepts in physics. Moreover, it has been concluded that one of the challenges lies in the teaching methodology. To address this, Georgia State University has begun teaching studio algebra-based physics. Although many institutions have implemented studio physics, most have done so in calculus-based sequences. The effectiveness of the studio approach in an algebra-based introductory physics course needs further investigation. A 3-semester study assessing the effectiveness of studio physics in an algebra-based physics sequence has been performed. This study compares the results of student pre- and post-tests using the Force Concept Inventory. Using the results from this assessment tool, we will discuss the effectiveness of the studio approach to teaching physics at GSU.

  8. Identification and functional analysis of cassava DELLA proteins in plant disease resistance against cassava bacterial blight.

    PubMed

    Li, Xiaolin; Liu, Wen; Li, Bing; Liu, Guoyin; Wei, Yunxie; He, Chaozu; Shi, Haitao

    2018-03-01

    Gibberellin (GA) is an essential plant hormone in plant growth and development as well as various stress responses. DELLA proteins are important repressors of GA signal pathway. GA and DELLA have been extensively investigated in several model plants. However, the in vivo roles of GA and DELLA in cassava, one of the most important crops and energy crops in the tropical area, are unknown. In this study, systematic genome-wide analysis identified 4 MeDELLAs in cassava, as evidenced by the evolutionary tree, gene structures and motifs analyses. Gene expression analysis found that 4 MeDELLAs were commonly regulated by flg22 and Xanthomonas axonopodis pv manihotis (Xam). Through overexpression in Nicotiana benthamiana, we found that 4 MeDELLAs conferred improved disease resistance against cassava bacterial blight. Through virus-induced gene silencing (VIGS) in cassava, we found that MeDELLA-silenced plants exhibited decreased disease resistance, with less callose deposition and lower transcript levels of defense-related genes. This is the first study identifying MeDELLAs as positive regulators of disease resistance against cassava bacterial blight. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  9. Connecting Inspiration with Information: Studio Art Students and Information Literacy Instruction

    ERIC Educational Resources Information Center

    Greer, Katie

    2015-01-01

    This article discusses the partnership between the library and the studio art faculty at Oakland University that led to the integration of information literacy instruction into the studio art curriculum. The author outlines the importance of information literacy to artistic practice and student success, and discusses the program of instruction and…

  10. Bombs Away: Visual Thinking and Students' Engagement in Design Studios Contexts

    ERIC Educational Resources Information Center

    Chamorro-Koc, Marianella; Scott, Andrew; Coombs, Gretchen

    2015-01-01

    In design studio, sketching or visual thinking is part of processes that assist students to achieve final design solutions. At Queensland University of Technology's (QUT's) First and Third Year industrial design studio classes we engage in a variety of teaching pedagogies from which we identify "Concept Bombs" as instrumental in the…

  11. Plum Fruit Development Occurs via Gibberellin–Sensitive and –Insensitive DELLA Repressors

    PubMed Central

    El-Sharkawy, Islam; Sherif, Sherif; Abdulla, Mahboob

    2017-01-01

    Fruit growth depends on highly coordinated hormonal activities. The phytohormone gibberellin (GA) promotes growth by triggering degradation of the growth-repressing DELLA proteins; however, the extent to which such proteins contribute to GA-mediated fruit development remains to be clarified. Three new plum genes encoding DELLA proteins, PslGAI, PslRGL and PslRGA were isolated and functionally characterized. Analysis of expression profile during fruit development suggested that PslDELLA are transcriptionally regulated during flower and fruit ontogeny with potential positive regulation by GA and ethylene, depending on organ and developmental stage. PslGAI and PslRGL deduced proteins contain all domains present in typical DELLA proteins. However, PslRGA exhibited a degenerated DELLA domain and subsequently lacks in GID1–DELLA interaction property. PslDELLA–overexpression in WT Arabidopsis caused dramatic disruption in overall growth including root length, stem elongation, plant architecture, flower structure, fertility, and considerable retardation in development due to dramatic distortion in GA-metabolic pathway. GA treatment enhanced PslGAI/PslRGL interaction with PslGID1 receptors, causing protein destabilization and relief of growth-restraining effect. By contrast, PslRGA protein was not degraded by GA due to its inability to interact with PslGID1. Relative to other PslDELLA–mutants, PslRGA–plants displayed stronger constitutive repressive growth that was irreversible by GA application. The present results describe additional complexities in GA-signalling during plum fruit development, which may be particularly important to optimize successful reproductive growth. PMID:28076366

  12. Red blood cell oleic acid levels reflect olive oil intake while omega-3 levels reflect fish intake and the use of omega-3 acid ethyl esters: The Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico-Heart Failure trial.

    PubMed

    Harris, William S; Masson, Serge; Barlera, Simona; Milani, Valentina; Pileggi, Silvana; Franzosi, Maria Grazia; Marchioli, Roberto; Tognoni, Gianni; Tavazzi, Luigi; Latini, Roberto

    2016-09-01

    The Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico-Heart Failure (GISSI-HF) study reported benefits of n-3 fatty acid (FA) treatment on cardiovascular (CV) events, but the effects of treatment on a putative CV disease risk factor, the red blood cell (RBC) n-3 FA level (the omega-3 index), have not been examined in this context. We hypothesized that treatment with prescription omega-3 acid ethyl esters (O3AEE) would increase the omega-3 index to the proposed cardioprotective value of 8%. RBCs were collected from a subset of patients participating in the GISSI-HF study (n=461 out of 6975 randomized), at baseline and after 3 months of treatment with either an olive oil placebo or O3AEE (1 g/d). RBC FA levels were expressed as a percentage of total FA. Patients also reported their typical olive oil and fish intakes. RBC oleic acid levels were directly correlated with reported frequency of olive oil consumption, and the omega-3 index was correlated with reported fish intake (P for trends <0.001 for both). After treatment, the omega-3 index increased from 4.8±1.7% to 6.7±1.9% but was unchanged in the placebo group (4.7±1.7 to 4.8±1.5%) (P<.0001 for changes between groups). At 3 months, more patients reached the proposed target omega-3 index level of 8%-12% in the treated vs placebo group (22.6% vs. 1.3%, P<.0001), however, what omega-3 index levels were ultimately achieved after four years in this trial are unknown. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Preparedness Portfolios and Portfolio Studios

    ERIC Educational Resources Information Center

    Turns, Jennifer; Sattler, Brook; Eliot, Matt; Kilgore, Deborah; Mobrand, Kathryn

    2012-01-01

    We live in a time of great enthusiasm for the role that e-Portfolios can play in education and a time of exploration in which educators and researchers are investigating different approaches to using ePortfolios to differentially support educational goals. In this paper, we focus on preparedness portfolios and portfolio studios as two key…

  14. The Hybrid Studio--Introducing Google+ as a Blended Learning Platform for Architectural Design Studio Teaching

    ERIC Educational Resources Information Center

    Steinø, Nicolai; Khalid, Md. Saufuddin

    2017-01-01

    Much architecture and design teaching is based on the studio format, where the co-presence in time and space of students, instructors and physical learning artefacts form a triangle from which the learning emerges. Yet with the advent of online communication platforms and learning management systems (LMS), there is reason to study how these…

  15. Class I TCP-DELLA interactions in inflorescence shoot apex determine plant height.

    PubMed

    Davière, Jean-Michel; Wild, Michael; Regnault, Thomas; Baumberger, Nicolas; Eisler, Herfried; Genschik, Pascal; Achard, Patrick

    2014-08-18

    Regulation of plant height, one of the most important agronomic traits, is the focus of intensive research for improving crop performance. Stem elongation takes place as a result of repeated cell divisions and subsequent elongation of cells produced by apical and intercalary meristems. The gibberellin (GA) phytohormones have long been known to control stem and internodal elongation by stimulating the degradation of nuclear growth-repressing DELLA proteins; however, the mechanism allowing GA-responsive growth is only slowly emerging. Here, we show that DELLAs directly regulate the activity of the plant-specific class I TCP transcription factor family, key regulators of cell proliferation. Our results demonstrate that class I TCP factors directly bind the promoters of core cell-cycle genes in Arabidopsis inflorescence shoot apices while DELLAs block TCP function by binding to their DNA-recognition domain. GAs antagonize such repression by promoting DELLA destruction and therefore cause a concomitant accumulation of TCP factors on promoters of cell-cycle genes. Consistent with this model, the quadruple mutant tcp8 tcp14 tcp15 tcp22 exhibits severe dwarfism and reduced responsiveness to GA action. Altogether, we conclude that GA-regulated DELLA-TCP interactions in inflorescence shoot apex provide a novel mechanism to control plant height. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Prognostic impact of elevated serum uric acid levels on long-term outcomes in patients with chronic heart failure: A post-hoc analysis of the GISSI-HF (Gruppo Italiano per lo Studio della Sopravvivenza nella Insufficienza Cardiaca-Heart Failure) trial.

    PubMed

    Mantovani, Alessandro; Targher, Giovanni; Temporelli, Pier Luigi; Lucci, Donata; Gonzini, Lucio; Nicolosi, Gian Luigi; Marchioli, Roberto; Tognoni, Gianni; Latini, Roberto; Cosmi, Franco; Tavazzi, Luigi; Maggioni, Aldo Pietro

    2018-06-01

    The prognostic impact of hyperuricemia on long-term clinical outcomes in patients with chronic heart failure (HF) has been investigated in observational registries and clinical trials, but the results have been often inconclusive. We examined the prognostic impact of elevated serum uric acid levels on long-term clinical outcomes in the GISSI-HF (Gruppo Italiano per lo Studio della Sopravvivenza nella Insufficienza Cardiaca-Heart Failure) trial. CLINICALTRIALS. NCT00336336. We assessed the rates of all-cause death, cardiovascular death, cardiovascular hospitalization and the composite of all-cause death or cardiovascular hospitalization over a median follow-up of 3.9 years among 6683 ambulatory patients with chronic HF. Patients in the 3rd serum uric acid tertile (>7.2 mg/dl) had a nearly 1.8-fold increased risk of both all-cause death and cardiovascular death, and a nearly 1.5-fold increased risk of cardiovascular hospitalization and of the composite endpoint compared to those in the 1st uric acid tertile (<5.7 mg/dl). Beyond serum uric acid ≥ 7 mg/dl the risk of outcomes increased sharply and linearly. The significant association between elevated serum uric acid levels and adverse outcomes persisted after adjustment for multiple established cardiovascular risk factors, HF etiology, left ventricular ejection fraction, medication use and other potential confounders, with an adjusted hazard ratio of 1.37 (95% CI 1.22-1.55) for all-cause death, 1.48 (1.29-1.69) for cardiovascular death, 1.19 (1.09-1.30) for cardiovascular hospitalization and 1.21 (1.11-1.31) for the composite endpoint, respectively. Elevated serum uric acid levels are independently associated with poor long-term survival and increased risk of cardiovascular hospitalization in patients with chronic HF. Copyright © 2018 Elsevier Inc. All rights reserved.

  17. The "Right Kind of Telling": Knowledge Building in the Academic Design Studio

    ERIC Educational Resources Information Center

    Cennamo, Katherine; Brandt, Carol

    2012-01-01

    Studio-based instruction, as traditionally enacted in design disciplines such as architecture, product design, graphic design, and the like, consists of dedicated desk space for each student, extended time blocks allocated to studio classes, and classroom interactions characterized by independent and group work on design problems supplemented by…

  18. The TimeStudio Project: An open source scientific workflow system for the behavioral and brain sciences.

    PubMed

    Nyström, Pär; Falck-Ytter, Terje; Gredebäck, Gustaf

    2016-06-01

    This article describes a new open source scientific workflow system, the TimeStudio Project, dedicated to the behavioral and brain sciences. The program is written in MATLAB and features a graphical user interface for the dynamic pipelining of computer algorithms developed as TimeStudio plugins. TimeStudio includes both a set of general plugins (for reading data files, modifying data structures, visualizing data structures, etc.) and a set of plugins specifically developed for the analysis of event-related eyetracking data as a proof of concept. It is possible to create custom plugins to integrate new or existing MATLAB code anywhere in a workflow, making TimeStudio a flexible workbench for organizing and performing a wide range of analyses. The system also features an integrated sharing and archiving tool for TimeStudio workflows, which can be used to share workflows both during the data analysis phase and after scientific publication. TimeStudio thus facilitates the reproduction and replication of scientific studies, increases the transparency of analyses, and reduces individual researchers' analysis workload. The project website ( http://timestudioproject.com ) contains the latest releases of TimeStudio, together with documentation and user forums.

  19. Traveling-Wave Tube Cold-Test Circuit Optimization Using CST MICROWAVE STUDIO

    NASA Technical Reports Server (NTRS)

    Chevalier, Christine T.; Kory, Carol L.; Wilson, Jeffrey D.; Wintucky, Edwin G.; Dayton, James A., Jr.

    2003-01-01

    The internal optimizer of CST MICROWAVE STUDIO (MWS) was used along with an application-specific Visual Basic for Applications (VBA) script to develop a method to optimize traveling-wave tube (TWT) cold-test circuit performance. The optimization procedure allows simultaneous optimization of circuit specifications including on-axis interaction impedance, bandwidth or geometric limitations. The application of Microwave Studio to TWT cold-test circuit optimization is described.

  20. STEM Studio: Where Innovation Generates Innovation

    ERIC Educational Resources Information Center

    Plonczak, Irene; Brooks, Jacqueline Grennon; Wilson, Gloria Lodato; Elijah, Rosebud; Caliendo, Julia

    2014-01-01

    STEM Studio at Hofstra University is a clinical practice site that brings together public school pupils and preservice teachers in settings with three features that lead to enhanced learning of all participants: classroom structures using multidisciplinary STEM tasks as platforms for learning; design challenge templates for diverse student…

  1. Prognostic Impact of Diabetes and Prediabetes on Survival Outcomes in Patients With Chronic Heart Failure: A Post-Hoc Analysis of the GISSI-HF (Gruppo Italiano per lo Studio della Sopravvivenza nella Insufficienza Cardiaca-Heart Failure) Trial.

    PubMed

    Dauriz, Marco; Targher, Giovanni; Temporelli, Pier Luigi; Lucci, Donata; Gonzini, Lucio; Nicolosi, Gian Luigi; Marchioli, Roberto; Tognoni, Gianni; Latini, Roberto; Cosmi, Franco; Tavazzi, Luigi; Maggioni, Aldo Pietro

    2017-07-05

    The independent prognostic impact of diabetes mellitus (DM) and prediabetes mellitus (pre-DM) on survival outcomes in patients with chronic heart failure has been investigated in observational registries and randomized, clinical trials, but the results have been often inconclusive or conflicting. We examined the independent prognostic impact of DM and pre-DM on survival outcomes in the GISSI-HF (Gruppo Italiano per lo Studio della Sopravvivenza nella Insufficienza Cardiaca-Heart Failure) trial. We assessed the risk of all-cause death and the composite of all-cause death or cardiovascular hospitalization over a median follow-up period of 3.9 years among the 6935 chronic heart failure participants of the GISSI-HF trial, who were stratified by presence of DM (n=2852), pre-DM (n=2013), and non-DM (n=2070) at baseline. Compared with non-DM patients, those with DM had remarkably higher incidence rates of all-cause death (34.5% versus 24.6%) and the composite end point (63.6% versus 54.7%). Conversely, both event rates were similar between non-DM patients and those with pre-DM. Cox regression analysis showed that DM, but not pre-DM, was associated with an increased risk of all-cause death (adjusted hazard ratio, 1.43; 95% CI, 1.28-1.60) and of the composite end point (adjusted hazard ratio, 1.23; 95% CI, 1.13-1.32), independently of established risk factors. In the DM subgroup, higher hemoglobin A1c was also independently associated with increased risk of both study outcomes (all-cause death: adjusted hazard ratio, 1.21; 95% CI, 1.02-1.43; and composite end point: adjusted hazard ratio, 1.14; 95% CI, 1.01-1.29, respectively). Presence of DM was independently associated with poor long-term survival outcomes in patients with chronic heart failure. URL: http://www.clinicaltrials.gov. Unique identifier: NCT00336336. © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

  2. Explorations in Teaching Sustainable Design: A Studio Experience in Interior Design/Architecture

    ERIC Educational Resources Information Center

    Gurel, Meltem O.

    2010-01-01

    This article argues that a design studio can be a dynamic medium to explore the creative potential of the complexity of sustainability from its technological to social ends. The study seeks to determine the impact of an interior design/architecture studio experience that was initiated to teach diverse meanings of sustainability and to engage the…

  3. Research on Chinese characters display of airborne MFD based on GL studio

    NASA Astrophysics Data System (ADS)

    Wang, Zhile; Dong, Junyu; Hu, Wenting; Cui, Yipeng

    2018-04-01

    GL Studio cannot display Chinese characters during developing the airborne MFD, this paper propose a method of establishing a Chinese character font with GB2312 encoding, establish the font table and the display unit of Chinese characters based on GL Studio. Abstract the storage and display data model of Chinese characters, parse the GB encoding of the corresponding Chinese characters that MFD received, find the coordinates of the Chinese characters in the font table, establish the dynamic control model and the dynamic display model of Chinese characters based on the display unit of Chinese characters. In GL Studio and VC ++.NET environment, this model has been successfully applied to develop the airborne MFD in a variety of mission simulators. This method has successfully solved the problem that GL Studio software cannot develop MFD software of Chinese domestic aircraft and can also be used for other professional airborne MFD development tools such as IDATA. It has been proved by experiments that this is a fast effective scalable and reconfigurable method of developing both actual equipment and simulators.

  4. Studio Physics at the Colorado School of Mines: A model for iterative development and assessment

    NASA Astrophysics Data System (ADS)

    Kohl, Patrick; Kuo, Vincent

    2009-05-01

    The Colorado School of Mines (CSM) has taught its first-semester introductory physics course using a hybrid lecture/Studio Physics format for several years. Based on this previous success, over the past 18 months we have converted the second semester of our traditional calculus-based introductory physics course (Physics II) to a Studio Physics format. In this talk, we describe the recent history of the Physics II course and of Studio at Mines, discuss the PER-based improvements that we are implementing, and characterize our progress via several metrics, including pre/post Conceptual Survey of Electricity and Magnetism (CSEM) scores, Colorado Learning About Science Survey scores (CLASS), failure rates, and exam scores. We also report on recent attempts to involve students in the department's Senior Design program with our course. Our ultimate goal is to construct one possible model for a practical and successful transition from a lecture course to a Studio (or Studio-like) course.

  5. Adapted Verbal Feedback, Instructor Interaction and Student Emotions in the Landscape Architecture Studio

    ERIC Educational Resources Information Center

    Smith, Carl A.; Boyer, Mark E.

    2015-01-01

    In light of concerns with architectural students' emotional jeopardy during traditional desk and final-jury critiques, the authors pursue alternative approaches intended to provide more supportive and mentoring verbal assessment in landscape architecture studios. In addition to traditional studio-based critiques throughout a semester, we provide…

  6. Investigating the Experiential Impact of Sensory Affect in Contemporary Communication Design Studio Education

    ERIC Educational Resources Information Center

    Marshalsey, Lorraine

    2015-01-01

    The studio is the primary site for learning in specialist Communication Design education worldwide. Differing higher education institutions, including art schools and university campuses, have developed a varied range of studio environments. These diverse learning spaces inherently create a complex fabric of affects. In addition, Communication…

  7. A consideration on physical tuning for acoustical coloration in recording studio

    NASA Astrophysics Data System (ADS)

    Shimizu, Yasushi

    2003-04-01

    Coloration due to particular architectural shapes and dimension or less surface absorption has been mentioned as an acoustical defect in recording studio. Generally interference among early reflected sounds arriving within 10 ms in delay after the direct sound produces coloration by comb filter effect over mid- and high-frequency sounds. In addition, less absorbed room resonance modes also have been well known as a major component for coloration in low-frequency sounds. Small size in dimension with recording studio, however, creates difficulty in characterization associated with wave acoustics behavior, that make acoustical optimization more difficult than that of concert hall acoustics. There still remains difficulty in evaluating amount of coloration as well as predicting its acoustical characteristics in acoustical modeling and in other words acoustical tuning technique during construction is regarded as important to optimize acoustics appropriately to the function of recording studio. This paper presents a example of coloration by comb filtering effect and less damped room modes in typical post-processing recording studio. And acoustical design and measurement technique will be presented for adjusting timbre due to coloration based on psycho-acoustical performance with binaural hearing and room resonance control with line array resonator adjusted to the particular room modes considered.

  8. Exploring Student Learning Profiles in Algebra-Based Studio Physics: A Person-Centered Approach

    ERIC Educational Resources Information Center

    Pond, Jarrad W. T.; Chini, Jacquelyn J.

    2017-01-01

    In this study, we explore the strategic self-regulatory and motivational characteristics of students in studio-mode physics courses at three universities with varying student populations and varying levels of success in their studio-mode courses. We survey students using questions compiled from several existing questionnaires designed to measure…

  9. Community Engagement Studios: A Structured Approach to Obtaining Meaningful Input From Stakeholders to Inform Research.

    PubMed

    Joosten, Yvonne A; Israel, Tiffany L; Williams, Neely A; Boone, Leslie R; Schlundt, David G; Mouton, Charles P; Dittus, Robert S; Bernard, Gordon R; Wilkins, Consuelo H

    2015-12-01

    Engaging communities in research increases its relevance and may speed the translation of discoveries into improved health outcomes. Many researchers lack training to effectively engage stakeholders, whereas academic institutions lack infrastructure to support community engagement. In 2009, the Meharry-Vanderbilt Community-Engaged Research Core began testing new approaches for community engagement, which led to the development of the Community Engagement Studio (CE Studio). This structured program facilitates project-specific input from community and patient stakeholders to enhance research design, implementation, and dissemination. Developers used a team approach to recruit and train stakeholders, prepare researchers to engage with stakeholders, and facilitate an in-person meeting with both. The research core has implemented 28 CE Studios that engaged 152 community stakeholders. Participating researchers, representing a broad range of faculty ranks and disciplines, reported that input from stakeholders was valuable and that the CE Studio helped determine project feasibility and enhanced research design and implementation. Stakeholders found the CE Studio to be an acceptable method of engagement and reported a better understanding of research in general. A tool kit was developed to replicate this model and to disseminate this approach. The research core will collect data to better understand the impact of CE Studios on research proposal submissions, funding, research outcomes, patient and stakeholder engagement in projects, and dissemination of results. They will also collect data to determine whether CE Studios increase patient-centered approaches in research and whether stakeholders who participate have more trust and willingness to participate in research.

  10. Community Engagement Studios: A Structured Approach to Obtaining Meaningful Input From Stakeholders to Inform Research

    PubMed Central

    Joosten, Yvonne A.; Israel, Tiffany L.; Williams, Neely A.; Boone, Leslie R.; Schlundt, David G.; Mouton, Charles P.; Dittus, Robert S.; Bernard, Gordon R.

    2015-01-01

    Problem Engaging communities in research increases its relevance and may speed the translation of discoveries into improved health outcomes. Many researchers lack training to effectively engage stakeholders, whereas academic institutions lack infrastructure to support community engagement. Approach In 2009, the Meharry-Vanderbilt Community-Engaged Research Core began testing new approaches for community engagement, which led to the development of the Community Engagement Studio (CE Studio). This structured program facilitates project-specific input from community and patient stakeholders to enhance research design, implementation, and dissemination. Developers used a team approach to recruit and train stakeholders, prepare researchers to engage with stakeholders, and facilitate an in-person meeting with both. Outcomes The research core has implemented 28 CE Studios that engaged 152 community stakeholders. Participating researchers, representing a broad range of faculty ranks and disciplines, reported that input from stakeholders was valuable and that the CE Studio helped determine project feasibility and enhanced research design and implementation. Stakeholders found the CE Studio to be an acceptable method of engagement and reported a better understanding of research in general. A tool kit was developed to replicate this model and to disseminate this approach. Next Steps The research core will collect data to better understand the impact of CE Studios on research proposal submissions, funding, research outcomes, patient and stakeholder engagement in projects, and dissemination of results. They will also collect data to determine whether CE Studios increase patient-centered approaches in research and whether stakeholders who participate have more trust and willingness to participate in research. PMID:26107879

  11. Beyond Classroom, Lab, Studio and Field

    NASA Astrophysics Data System (ADS)

    Waller, J. L.; Brey, J. A.; DeMuynck, E.; Weglarz, T. C.

    2017-12-01

    When the arts work in tandem with the sciences, the insights of these disciplines can be easily shared and teaching and learning are enriched. Our shared experiences in classroom/lab/studio instruction and in art and science based exhibitions reward all involved. Our individual disciplines cover a wide range of content- Art, Biology, Geography, Geology- yet we connect on aspects that link to the others'. We easily move from lab to studio and back again as we teach—as do our students as they learn! Art and science education can take place outside labs and studios through study abroad, international workshops, museum or gallery spaces, and in forums like the National Academies' programs. We can reach our neighbors at local public gatherings, nature centers and libraries. Our reach is extended in printed publications and in conferences. We will describe some of our activities listed above, with special focus on exhibitions: "Layers: Places in Peril"; "small problems, BIG TROUBLE" and the in-progress "River Bookends: Headwaters, Delta and the Volume of Stories In Between". Through these, learning and edification take place between the show and gallery visitors and is extended via class visits and related assignments, field trips for child and adult learners, interviews, films and panel presentations. These exhibitions offer the important opportunities for exhibit- participating scientists to find common ground with each other about their varied work. We will highlight a recent collaborative show opening a new university-based environmental research center and the rewarding activities there with art and science students and professors. We will talk about the learning enhancement added through a project that brought together a physical geography and a painting class. We will explore how students shared the form and content of their research projects with each other and then, became the educators through paintings and text of their geoscience topics on gallery walls.

  12. O-GlcNAcylation of master growth repressor DELLA by SECRET AGENT modulates multiple signaling pathways in Arabidopsis

    PubMed Central

    Zentella, Rodolfo; Hu, Jianhong; Hsieh, Wen-Ping; Matsumoto, Peter A.; Dawdy, Andrew; Barnhill, Benjamin; Oldenhof, Harriëtte; Hartweck, Lynn M.; Maitra, Sushmit; Thomas, Stephen G.; Cockrell, Shelley; Boyce, Michael; Shabanowitz, Jeffrey; Hunt, Donald F.; Olszewski, Neil E.; Sun, Tai-ping

    2016-01-01

    The DELLA family of transcription regulators functions as master growth repressors in plants by inhibiting phytohormone gibberellin (GA) signaling in response to developmental and environmental cues. DELLAs also play a central role in mediating cross-talk between GA and other signaling pathways via antagonistic direct interactions with key transcription factors. However, how these crucial protein–protein interactions can be dynamically regulated during plant development remains unclear. Here, we show that DELLAs are modified by the O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) SECRET AGENT (SEC) in Arabidopsis. O-GlcNAcylation of the DELLA protein REPRESSOR OF ga1-3 (RGA) inhibits RGA binding to four of its interactors—PHYTOCHROME-INTERACTING FACTOR3 (PIF3), PIF4, JASMONATE-ZIM DOMAIN1, and BRASSINAZOLE-RESISTANT1 (BZR1)—that are key regulators in light, jasmonate, and brassinosteroid signaling pathways, respectively. Consistent with this, the sec-null mutant displayed reduced responses to GA and brassinosteroid and showed decreased expression of several common target genes of DELLAs, BZR1, and PIFs. Our results reveal a direct role of OGT in repressing DELLA activity and indicate that O-GlcNAcylation of DELLAs provides a fine-tuning mechanism in coordinating multiple signaling activities during plant development. PMID:26773002

  13. O-GlcNAcylation of master growth repressor DELLA by SECRET AGENT modulates multiple signaling pathways in Arabidopsis.

    PubMed

    Zentella, Rodolfo; Hu, Jianhong; Hsieh, Wen-Ping; Matsumoto, Peter A; Dawdy, Andrew; Barnhill, Benjamin; Oldenhof, Harriëtte; Hartweck, Lynn M; Maitra, Sushmit; Thomas, Stephen G; Cockrell, Shelley; Boyce, Michael; Shabanowitz, Jeffrey; Hunt, Donald F; Olszewski, Neil E; Sun, Tai-Ping

    2016-01-15

    The DELLA family of transcription regulators functions as master growth repressors in plants by inhibiting phytohormone gibberellin (GA) signaling in response to developmental and environmental cues. DELLAs also play a central role in mediating cross-talk between GA and other signaling pathways via antagonistic direct interactions with key transcription factors. However, how these crucial protein-protein interactions can be dynamically regulated during plant development remains unclear. Here, we show that DELLAs are modified by the O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) SECRET AGENT (SEC) in Arabidopsis. O-GlcNAcylation of the DELLA protein REPRESSOR OF ga1-3 (RGA) inhibits RGA binding to four of its interactors-PHYTOCHROME-INTERACTING FACTOR3 (PIF3), PIF4, JASMONATE-ZIM DOMAIN1, and BRASSINAZOLE-RESISTANT1 (BZR1)-that are key regulators in light, jasmonate, and brassinosteroid signaling pathways, respectively. Consistent with this, the sec-null mutant displayed reduced responses to GA and brassinosteroid and showed decreased expression of several common target genes of DELLAs, BZR1, and PIFs. Our results reveal a direct role of OGT in repressing DELLA activity and indicate that O-GlcNAcylation of DELLAs provides a fine-tuning mechanism in coordinating multiple signaling activities during plant development. © 2016 Zentella et al.; Published by Cold Spring Harbor Laboratory Press.

  14. Exploring student learning profiles in algebra-based studio physics: A person-centered approach

    NASA Astrophysics Data System (ADS)

    Pond, Jarrad W. T.; Chini, Jacquelyn J.

    2017-06-01

    In this study, we explore the strategic self-regulatory and motivational characteristics of students in studio-mode physics courses at three universities with varying student populations and varying levels of success in their studio-mode courses. We survey students using questions compiled from several existing questionnaires designed to measure students' study strategies, attitudes toward and motivations for learning physics, organization of scientific knowledge, experiences outside the classroom, and demographics. Using a person-centered approach, we utilize cluster analysis methods to group students into learning profiles based on their individual responses to better understand the strategies and motives of algebra-based studio physics students. Previous studies have identified five distinct learning profiles across several student populations using similar methods. We present results from first-semester and second-semester studio-mode introductory physics courses across three universities. We identify these five distinct learning profiles found in previous studies to be present within our population of introductory physics students. In addition, we investigate interactions between these learning profiles and student demographics. We find significant interactions between a student's learning profile and their experience with high school physics, major, gender, grade expectation, and institution. Ultimately, we aim to use this method of analysis to take the characteristics of students into account in the investigation of successful strategies for using studio methods of physics instruction within and across institutions.

  15. 8 CFR 332.2 - Establishment of photographic studios.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... naturalization laws. Such studios must be in a building occupied by the Service and be conducted under the supervision of the district director. Each sponsoring organization shall submit an annual accounting of the...

  16. Opening New Doors: Hands-On Participation Brings a New Audience to the Clay Studio. Wallace Studies in Building Arts Audiences

    ERIC Educational Resources Information Center

    Harlow, Bob; Heywood, Tricia

    2015-01-01

    This case study examines how The Clay Studio, a ceramic-arts studio, gallery and shop in Philadelphia, attracted younger audiences to its workshops and exhibits. In 2007, the studio became concerned that its audience was getting older and few newcomers were signing up for classes or making purchases. The studio had to engage younger professionals…

  17. GA-DELLA pathway is involved in regulation of nitrogen deficiency-induced anthocyanin accumulation.

    PubMed

    Zhang, Yongqiang; Liu, Zhongjuan; Liu, Jianping; Lin, Sheng; Wang, Jianfeng; Lin, Wenxiong; Xu, Weifeng

    2017-04-01

    DELLA proteins positively regulate nitrogen deficiency-induced anthocyanin accumulation through directly interaction with PAP1 to enhance its transcriptional activity on anthocyanin biosynthetic gene expressions. Plants can survive a limiting nitrogen supply by undergoing adaptive responses, including induction of anthocyanin production. However, the detailed mechanism is still unclear. In this study, we found that this process was impaired and enhanced, respectively, by exogenous GA 3 (an active form of GAs) and paclobutrazol (PAC, a specific GA biosynthesis inhibitor) in Arabidopsis seedlings. Consistently, the nitrogen deficiency-induced transcript levels of several key genes involved in anthocyanin biosynthesis, including F3'H, DFR, LDOX, and UF3GT, were decreased and enhanced by exogenous GA 3 and PAC, respectively. Moreover, the nitrogen deficiency-induced anthocyanin accumulation and biosynthesis gene expressions were impaired in the loss-of-function mutant gai-t6/rga-t2/rgl1-1/rgl2-1/rgl3-1 (della) but enhanced in the GA-insensitive mutant gai, suggesting that DELLA proteins, known as repressors of GA signaling, are necessary for fully induction of nitrogen deficiency-driven anthocyanin biosynthesis. Using yeast two-hybrid (Y2H) assay, pull-down assay, and luciferase complementation assay, it was found that RGA, a DELLA of Arabidopsis, could strongly interact with PAP1, a known regulatory transcription factor positively involved in anthocyanin biosynthesis. Furthermore, transient expression assays indicated that RGA and GAI could enhance the transcriptional activities of PAP1 on its downstream genes, including F3'H and DFR. Taken together, this study suggests that DELLAs are necessary regulators for nitrogen deficiency-induced anthocyanin accumulation through interaction with PAP1 and enhancement of PAP1's transcriptional activity on its target genes. GA-DELLA-involved anthocyanin accumulation is important for plant adaptation to nitrogen deficiency.

  18. Formalizing the First Day in an Organic Chemistry Laboratory Using a Studio-Based Approach

    ERIC Educational Resources Information Center

    Collison, Christina G.; Cody, Jeremy; Smith, Darren; Swartzenberg, Jennifer

    2015-01-01

    A novel studio-based lab module that incorporates student-centered activities was designed and implemented to introduce second-year undergraduate students to the first-semester organic chemistry laboratory. The "First Day" studio module incorporates learning objectives for the course, lab safety, and keeping a professional lab notebook.

  19. An interdisciplinary lighting design studio: Opportunities and challenges of collaborative learning

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guzowski, M.; Ginthner, D.

    1997-12-31

    Interdisciplinary study is based on the proposition that collaboration will enrich and expand understanding within a discipline and will also reveal connections to other fields of study, the community, the natural environment, etc. This study, the community, the natural environment, etc. This paper will present the results of a collaborative lighting design studio which was conducted by the Department of Architecture and the Interior Design Program at the University of Minnesota. The objectives of the studio were threefold: (1) To provide an opportunity for collaboration between students in design disciplines, (2) to introduce students to collaboration with design practitioners andmore » clients, and (3) to expose students to interdisciplinary work prior to graduation. Three projects by local firms were used for the design investigation. The following discussion will explore the opportunities and challenges of collaborative education and the interdisciplinary design studio. The objectives, roles of the teachers and the students, coursework, and future directions will be considered.« less

  20. Tissue Paper Economics and Other Hidden Dimensions of the Studio Model of Art Instruction.

    ERIC Educational Resources Information Center

    Hamblen, Karen A.

    1983-01-01

    Despite calls for change and numerous proposed alternatives, art education remains committed to the studio model. The retention of the status quo may be related to the economics of art studio materials and especially to the extensive advertising of art supply companies in art teachers' journals. (Author/IS)

  1. The effects of DELLAs on growth change with developmental stage and brassinosteroid levels.

    PubMed

    Stewart Lilley, Jodi L; Gan, Yinbo; Graham, Ian A; Nemhauser, Jennifer L

    2013-10-01

    There are two stages in photomorphogenesis. First, seedlings detect light and open their cotyledons. Second, seedlings optimize their light environment by controlled elongation of the seedling stem or hypocotyl. In this study, we used time-lapse imaging to investigate the relationship between the brassinosteroid (BR) and gibberellin (GA) hormones across both stages of photomorphogenesis. During the transition between one stage and the other, growth promotion by BRs and GAs switched from an additive to a synergistic relationship. Molecular genetic analysis revealed unexpected roles for known participants in the GA pathway during this period. Members of the DELLA family could either repress or enhance BR growth responses, depending on developmental stage. At the transition point for seedling growth dynamics, the BR and GA pathways had opposite effects on DELLA protein levels. In contrast to GA-induced DELLA degradation, BR treatments increased the levels of REPRESSOR of ga1-3 (RGA) and mimicked the molecular effects of stabilizing DELLAs. In addition, DELLAs showed complex regulation of genes involved in BR biosynthesis, implicating them in BR homeostasis. Growth promotion by GA alone depended on the PHYTOCHROME INTERACTING FACTOR (PIF) family of master growth regulators. The effects of BR, including the synergistic effects with GA, were largely independent of PIFs. These results point to a multi-level, dynamic relationship between the BR and GA pathways. © 2013 The Authors The Plant Journal © 2013 John Wiley & Sons Ltd.

  2. Exploring the Context of Change: Understanding the Kinetics of a Studio Physics Implementation Effort

    ERIC Educational Resources Information Center

    Enderle, Patrick J.; Southerland, Sherry A.; Grooms, Jonathon A.

    2013-01-01

    The SCALE-UP studio physics class involves the physical redesign of a classroom to encourage more collaborative interactions and student-centered teaching, an approach shown to increase student learning on several different measures. However, research into the contextual issues involved in implementing a studio course using the SCALE-UP model…

  3. The Traditional Non-Traditional Landscape Architecture Studio: Education through Service Learning in Miami, OK

    ERIC Educational Resources Information Center

    Loon, Leehu

    2010-01-01

    This research will illustrate the importance of a recent service learning project that was conducted for Miami, Oklahoma, by landscape architecture graduate students and faculty of the University of Oklahoma. Students and faculty partnered with the community to form the studio design team. Education in the landscape architecture studio at the…

  4. The Technique of the Sound Studio: Radio, Record Production, Television, and Film. Revised Edition.

    ERIC Educational Resources Information Center

    Nisbett, Alec

    Detailed explanations of the studio techniques used in radio, record, television, and film sound production are presented in as non-technical language as possible. An introductory chapter discusses the physics and physiology of sound. Subsequent chapters detail standards for sound control in the studio; explain the planning and routine of a sound…

  5. Reducing Anxiety: Studio Strategies for Performing Salvation

    ERIC Educational Resources Information Center

    Riley, Jessica M.

    2012-01-01

    This article offers a brief overview of the causes and manifestations of performance anxiety and suggests methods for professors to combat it in the studio setting. The topics of mentoring, physical and mental relaxation, dietary health, and imaging are explored. Primary source material is referred to throughout the article, so readers can easily…

  6. Plant cytoskeleton: DELLA connects gibberellins to microtubules.

    PubMed

    Dixit, Ram

    2013-06-03

    A new study reveals that DELLA proteins directly interact with the prefoldin complex, thus regulating tubulin subunit availability in a gibberellin-dependent manner. This finding provides a mechanistic link between the growth-promoting plant hormone gibberellin and cortical microtubule organization. Copyright © 2013 Elsevier Ltd. All rights reserved.

  7. A New Paradigm for Design Studio Education

    ERIC Educational Resources Information Center

    Wang, Tsungjuang

    2010-01-01

    There is a feeling among many design educators today that the discipline has reached a crisis in its development, and that change is needed immediately in the way that design educators articulate their epistemology and their methodology. The architectural studio can be seen as the model for design education, and its culture is exemplary. Donald…

  8. Rotational Critique System as a Method of Culture Change in an Architecture Design Studio: Urban Design Studio as Case Study

    ERIC Educational Resources Information Center

    Fasli, Mukaddes; Hassanpour, Badiossadat

    2017-01-01

    In this century, all educational efforts strive to achieve quality assurance standards. Therefore, it will be naive to deny the existence of problems in architectural education. The current design studio critique method has been developed upon generations of students and educators. Architectural education is changing towards educating critical…

  9. The Studio Experience at the University of Georgia: An Example of Constructionist Learning for Adults

    ERIC Educational Resources Information Center

    Clinton, Gregory; Rieber, Lloyd P.

    2010-01-01

    The Studio curriculum in the Learning, Design, and Technology (formerly Instructional Technology) program at a large research-extensive university in the southeastern U.S. represents a deliberate application of contemporary theory of how adults learn complex information in ill-structured domains. The Studio curriculum, part of a graduate program…

  10. Time Frequency Analysis and Spatial Filtering in the Evaluation of Beta ERS After Finger Movement

    DTIC Science & Technology

    2001-10-25

    Italy. 5IRCCS Fondazione Santa Lucia , via Ardeatina 306, Roma, Italy Fig. 1 Scheme of the Wavelet Packet decomposition. The gray boxes represent...surface splines. J. Aircraft, 1972, 9: 189-191. [8]Maceri, B., Magnone, S., Bianchi, A., Cerutti, S. Studio della decomposizione wavelet dei segnali

  11. Integrating Blended and Problem-Based Learning into an Architectural Housing Design Studio: A Case Study

    ERIC Educational Resources Information Center

    Bregger, Yasemin Alkiser

    2017-01-01

    This paper presents how a blended learning pedagogic model is integrated into an architectural design studio by adapting the problem-based learning process and housing issues in Istanbul Technical University (ITU), during fall 2015 and spring 2016 semesters for fourth and sixth level students. These studios collaborated with the "Introduction…

  12. A Survey of Equipment in the Singing Voice Studio and Its Perceived Effectiveness by Vocologists and Student Singers.

    PubMed

    Gerhard, Julia; Rosow, David E

    2016-05-01

    Speech-language pathologists have long used technology for the clinical measurement of the speaking voice, but present research shows that vocal pedagogues and voice students are becoming more accepting of technology in the studio. As a result, the equipment and technology used in singing voice studios by speech-language pathologists and vocal pedagogues are changing. Although guides exist regarding equipment and technology necessary for developing a voice laboratory and private voice studio, there are no data documenting the current implementation of these items and their perceived effectiveness. This study seeks to document current trends in equipment used in voice laboratories and studios. Two separate surveys were distributed to 60 vocologists and approximately 300 student singers representative of the general singing student population. The surveys contained questions about the inventory of items found in voice studios and perceived effectiveness of these items. Data were analyzed using descriptive analyses and statistical analyses when applicable. Twenty-six of 60 potential vocologists responded, and 66 student singers responded. The vocologists reported highly uniform inventories and ratings of studio items. There were wide-ranging differences between the inventories reported by the vocologist and student singer groups. Statistically significant differences between ratings of effectiveness of studio items were found for 11 of the 17 items. In all significant cases, vocologists rated usefulness to be higher than student singers. Although the order of rankings of vocologists and student singers was similar, a much higher percentage of vocologists report the items as being efficient and effective than students. The historically typical studio items, including the keyboard and mirror, were ranked as most effective by both vocologists and student singers. Copyright © 2016 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  13. DELLA proteins regulate expression of a subset of AM symbiosis-induced genes in Medicago truncatula.

    PubMed

    Floss, Daniela S; Lévesque-Tremblay, Véronique; Park, Hee-Jin; Harrison, Maria J

    2016-01-01

    The majority of the vascular flowering plants form symbiotic associations with fungi from the phylum Glomeromycota through which both partners gain access to nutrients, either mineral nutrients in the case of the plant, or carbon, in the case of the fungus. (1) The association develops in the roots and requires substantial remodeling of the root cortical cells where branched fungal hyphae, called arbuscules, are housed in a new membrane-bound apoplastic compartment. (2) Nutrient exchange between the symbionts occurs over this interface and its development and maintenance is critical for symbiosis. Previously, we showed that DELLA proteins, which are well known as repressors of gibberellic acid signaling, also regulate development of AM symbiosis and are necessary to enable arbuscule development. (3) Furthermore, constitutive overexpression of a dominant DELLA protein (della1-Δ18) is sufficient to induce transcripts of several AM symbiosis-induced genes, even in the absence of the fungal symbiont. (4) Here we further extend this approach and identify AM symbiosis genes that respond transcriptionally to constitutive expression of a dominant DELLA protein and also genes that do respond to this treatment. Additionally, we demonstrate that DELLAs interact with REQUIRED FOR ARBUSCULE DEVELOPMENT 1 (RAD1) which further extends our knowledge of GRAS factor complexes that have the potential to regulate gene expression during AM symbiosis.

  14. DELLA proteins regulate expression of a subset of AM symbiosis-induced genes in Medicago truncatula

    PubMed Central

    Floss, Daniela S.; Lévesque-Tremblay, Véronique; Park, Hee-Jin; Harrison, Maria J.

    2016-01-01

    ABSTRACT The majority of the vascular flowering plants form symbiotic associations with fungi from the phylum Glomeromycota through which both partners gain access to nutrients, either mineral nutrients in the case of the plant, or carbon, in the case of the fungus.1 The association develops in the roots and requires substantial remodeling of the root cortical cells where branched fungal hyphae, called arbuscules, are housed in a new membrane-bound apoplastic compartment.2 Nutrient exchange between the symbionts occurs over this interface and its development and maintenance is critical for symbiosis. Previously, we showed that DELLA proteins, which are well known as repressors of gibberellic acid signaling, also regulate development of AM symbiosis and are necessary to enable arbuscule development.3 Furthermore, constitutive overexpression of a dominant DELLA protein (della1-Δ18) is sufficient to induce transcripts of several AM symbiosis-induced genes, even in the absence of the fungal symbiont.4 Here we further extend this approach and identify AM symbiosis genes that respond transcriptionally to constitutive expression of a dominant DELLA protein and also genes that do respond to this treatment. Additionally, we demonstrate that DELLAs interact with REQUIRED FOR ARBUSCULE DEVELOPMENT 1 (RAD1) which further extends our knowledge of GRAS factor complexes that have the potential to regulate gene expression during AM symbiosis. PMID:26984507

  15. Understanding the Signature Pedagogy of the Design Studio and the Opportunities for Its Technological Enhancement

    ERIC Educational Resources Information Center

    Crowther, Phillip

    2013-01-01

    This paper presents an analysis of the studio as the signature pedagogy of design education. A number of theoretical models of learning, pedagogy, and education are used to interrogate the studio for its advantages and shortcomings, and to identify opportunities for the integration of new technologies and to explore the affordances that they…

  16. Envision and Observe: Using the Studio Thinking Framework for Learning and Teaching in Digital Arts

    ERIC Educational Resources Information Center

    Sheridan, Kimberly M.

    2011-01-01

    The Studio Thinking Framework (STF) focuses on habits of mind taught through studio arts rather than disciplinary content or media-specific techniques. It is well suited to integrate studies of arts learning and teaching in a range of contexts, and it provides a framework for understanding how visual arts participation is dramatically changing…

  17. Using Online Education Technologies to Support Studio Instruction

    ERIC Educational Resources Information Center

    Bender, Diane M.; Vredevoogd, Jon D.

    2006-01-01

    Technology is transforming the education and practice of architecture and design. The newest form of education is blended learning, which combines personal interaction from live class sessions with online education for greater learning flexibility (Abrams & Haefner, 2002). Reluctant to join the digital era are educators teaching studio courses…

  18. Re-Using of the Historical Buildings in the Context of Sustainablity: AN Architectural Design Studio Study on Old Girls Teacher Training School

    NASA Astrophysics Data System (ADS)

    Ulusoy, M.; Erdogan, E.; Erdogan, H. A.; Oral, M.

    2013-07-01

    Refunctioning is a widely used method for protecting historical structures. However, throughout architectural education, functioning historical structures and producing new designs in terms of historical pattern do not attract great attention within the framework of design studios. It is a fact that in such schools that abovementioned items are more popular, the connection between protection oriented studio and design studio is pretty weak. In this study refunctioning was discussed as a design studio topic in relation to the old girls' teacher training school and its immediate surroundings. The primary objective of this design studio is to increase architecture students' awareness in terms of visual and perceptual levels of project designs in historical patterns. Within the context of this manuscript, the experiences gained during design studio process were transferred and discussed.

  19. Studio Art Experience: The Heart of Art Education.

    ERIC Educational Resources Information Center

    Michael, John A.

    1980-01-01

    The author suggests that artist-trained teachers fail to understand that the creative studio art experience is the basis of art programs, and that a meaningful human education can come about through such an experience. He describes problems of the artist, and objectives of teaching and evaluating the art process. (KC)

  20. English 540: Teaching Stretch and Studio Composition Practicum

    ERIC Educational Resources Information Center

    Davila, Bethany; Elder, Cristyn L.

    2017-01-01

    In the course overview, the authors state that this course prepares those who enroll to teach Stretch and Studio Composition at the University of New Mexico by introducing relevant theory and pedagogy in the areas of basic writing, multilingual writing, metacognition, and reading instruction. While the English 537: Teaching Composition Practicum…

  1. Begging the Question: Performativity and Studio-Based Research

    ERIC Educational Resources Information Center

    Petelin, George

    2014-01-01

    The requirement that candidates in studio-based or practice-led higher degrees by research should formulate a research question has been found to be problematic by some writers. The present article argues that this stance, particularly as it is articulated by proponents of the influential category of "performative research" (Haseman,…

  2. 75 FR 65512 - Raleigh Film and Television Studios, LLC, Los Angeles, CA; Notice of Affirmative Determination...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-25

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-72,587] Raleigh Film and... (TAA) applicable to workers and former workers of Raleigh Film and Television Studios, LLC, Los Angeles... alleges that the subject firm ``is actively building large film studios in both Budapest, Hungary and...

  3. TMV-Cg Coat Protein stabilizes DELLA proteins and in turn negatively modulates salicylic acid-mediated defense pathway during Arabidopsis thaliana viral infection.

    PubMed

    Rodriguez, Maria Cecilia; Conti, Gabriela; Zavallo, Diego; Manacorda, Carlos Augusto; Asurmendi, Sebastian

    2014-08-03

    Plant viral infections disturb defense regulatory networks during tissue invasion. Emerging evidence demonstrates that a significant proportion of these alterations are mediated by hormone imbalances. Although the DELLA proteins have been reported to be central players in hormone cross-talk, their role in the modulation of hormone signaling during virus infections remains unknown. This work revealed that TMV-Cg coat protein (CgCP) suppresses the salicylic acid (SA) signaling pathway without altering defense hormone SA or jasmonic acid (JA) levels in Arabidopsis thaliana. Furthermore, it was observed that the expression of CgCP reduces plant growth and delays the timing of floral transition. Quantitative RT-qPCR analysis of DELLA target genes showed that CgCP alters relative expression of several target genes, indicating that the DELLA proteins mediate transcriptional changes produced by CgCP expression. Analyses by fluorescence confocal microscopy showed that CgCP stabilizes DELLA proteins accumulation in the presence of gibberellic acid (GA) and that the DELLA proteins are also stabilized during TMV-Cg virus infections. Moreover, DELLA proteins negatively modulated defense transcript profiles during TMV-Cg infection. As a result, TMV-Cg accumulation was significantly reduced in the quadruple-DELLA mutant Arabidopsis plants compared to wild type plants. Taken together, these results demonstrate that CgCP negatively regulates the salicylic acid-mediated defense pathway by stabilizing the DELLA proteins during Arabidopsis thaliana viral infection, suggesting that CgCP alters the stability of DELLAs as a mechanism of negative modulation of antiviral defense responses.

  4. Exploring Science in the Studio: NSF-Funded Initiatives to Increase Scientific Literacy in Undergraduate Art and Design Students

    NASA Astrophysics Data System (ADS)

    Metzger, C. A.

    2015-12-01

    The project Exploring Science in the Studio at California College of the Arts (CCA), one of the oldest and most influential art and design schools in the country, pursues ways to enable undergraduate students to become scientifically literate problem-solvers in a variety of careers and to give content and context to their creative practices. The two main branches of this National Science Foundation-funded project are a series of courses called Science in the Studio (SitS) and the design of the Mobile Units for Science Exploration (MUSE) system, which allow instructors to bring science equipment directly into the studios. Ongoing since 2010, each fall semester a series of interdisciplinary SitS courses are offered in the college's principal areas of study (architecture, design, fine arts, humanities and sciences, and diversity studies) thematically linked by Earth and environmental science topics such as water, waste, and sustainability. Each course receives funding to embed guest scientists from other colleges and universities, industry, or agriculture directly into the studio courses. These scientists worked in tandem with the studio faculty and gave lectures, led field trips, conducted studio visits, and advised the students' creative endeavors, culminating in an annual SitS exhibition of student work. The MUSE system, of fillable carts and a storage and display unit, was designed by undergraduate students in a Furniture studio who explored, experimented, and researched various ways science materials and equipment are stored, collected, and displayed, for use in the current and future science and studio curricula at CCA. Sustainable practices and "smart design" underpinned all of the work completed in the studio. The materials selected for the new Science Collection at CCA include environmental monitoring equipment and test kits, a weather station, a stream table, a rock and fossil collection, and a vertebrate skull collection. The SitS courses and MUSE system

  5. Thirdspace Explorations in Online Writing Studios: Writing Centers, Writing in the Disiplines and First Year Composition in the Corporate University

    ERIC Educational Resources Information Center

    Miley, Michelle L.

    2013-01-01

    This study explores the use of online writing studios housed in the University Writing Center and attached to a Writing in the Disciplines course in the College of Technology and a First Year Composition program. The original goal of the online writing studio, modified from Grego and Thompson's (2009) writing studio approach, was to create an…

  6. The DELLA Protein SLR1 Integrates and Amplifies Salicylic Acid- and Jasmonic Acid-Dependent Innate Immunity in Rice.

    PubMed

    De Vleesschauwer, David; Seifi, Hamed Soren; Filipe, Osvaldo; Haeck, Ashley; Huu, Son Nguyen; Demeestere, Kristof; Höfte, Monica

    2016-03-01

    Gibberellins are a class of tetracyclic plant hormones that are well known to promote plant growth by inducing the degradation of a class of nuclear growth-repressing proteins, called DELLAs. In recent years, GA and DELLAs are also increasingly implicated in plant responses to pathogen attack, although our understanding of the underlying mechanisms is still limited, especially in monocotyledonous crop plants. Aiming to further decipher the molecular underpinnings of GA- and DELLA-modulated plant immunity, we studied the dynamics and impact of GA and DELLA during infection of the model crop rice (Oryza sativa) with four different pathogens exhibiting distinct lifestyles and infection strategies. Opposite to previous findings in Arabidopsis (Arabidopsis thaliana), our findings reveal a prominent role of the DELLA protein Slender Rice1 (SLR1) in the resistance toward (hemi)biotrophic but not necrotrophic rice pathogens. Moreover, contrary to the differential effect of DELLA on the archetypal defense hormones salicylic acid (SA) and jasmonic acid (JA) in Arabidopsis, we demonstrate that the resistance-promoting effect of SLR1 is due at least in part to its ability to boost both SA- and JA-mediated rice defenses. In a reciprocal manner, we found JA and SA treatment to interfere with GA metabolism and stabilize SLR1. Together, these findings favor a model whereby SLR1 acts as a positive regulator of hemibiotroph resistance in rice by integrating and amplifying SA- and JA-dependent defense signaling. Our results highlight the differences in hormone defense networking between rice and Arabidopsis and underscore the importance of GA and DELLA in molding disease outcomes. © 2016 American Society of Plant Biologists. All Rights Reserved.

  7. Introductory Physics Gender Gaps: Pre- and Post-Studio Transition

    NASA Astrophysics Data System (ADS)

    Kohl, Patrick B.; Kuo, H. Vincent

    2009-11-01

    Prior work has characterized the gender gaps present in college-level introductory physics courses. Such work has also shown that research-based interactive engagement techniques can reduce or eliminate these gender gaps. In this paper, we study the gender gaps (and lack thereof) in the introductory calculus-based electricity and magnetism course at the Colorado School of Mines. We present eight semesters' worth of data, totaling 2577 students, with four semesters preceding a transition to Studio physics, and four following. We examine gender gaps in course grades, DFW (D grade, fail, or withdrawal) rates, and normalized gains on the Conceptual Survey of Electricity and Magnetism (CSEM), and consider factors such as student ACT scores and grades in prior math classes. We find little or no gap in male/female course grades and DFW rates, but substantial gaps in CSEM gains that are reduced somewhat by the transition to Studio physics.

  8. Standing Sound Waves in Air with DataStudio

    ERIC Educational Resources Information Center

    Kraftmakher, Yaakov

    2010-01-01

    Two experiments related to standing sound waves in air are adapted for using the ScienceWorkshop data-acquisition system with the DataStudio software from PASCO scientific. First, the standing waves are created by reflection from a plane reflector. The distribution of the sound pressure along the standing wave is measured. Second, the resonance…

  9. Social Work Learning Spaces: The Social Work Studio

    ERIC Educational Resources Information Center

    Zufferey, Carole; King, Sue

    2016-01-01

    This paper explores the contribution of a physical learning space to student engagement in social work education. Drawing on a constructivist methodology, this paper examines the findings of a survey conducted with students and staff in a social work and human service programme about their experiences of a Social Work Studio learning space. The…

  10. 47 CFR 73.1125 - Station main studio location.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... so doing would be consistent with the operation of the station in the public interest. (c) Each Class... respect to a group of commonly controlled stations, Class A stations whose predicted Grade B contours are physically contiguous to each other may locate their main studio within any of these contours. If a Class A...

  11. The Perceptions of Piano Teachers Regarding the Inclusion of Children with Disabilities in the Piano Studio

    ERIC Educational Resources Information Center

    Martiros, Melissa

    2012-01-01

    The purpose of this study was to begin to examine the factors that contribute to the inclusion and exclusion of children with disabilities in piano lessons in private studios. Specifically, using a qualitative approach. the perceptions piano teachers have regarding the inclusion of children with disabilities in the piano studio were studied. The…

  12. Internet virtual studio: low-cost augmented reality system for WebTV

    NASA Astrophysics Data System (ADS)

    Sitnik, Robert; Pasko, Slawomir; Karaszewski, Maciej; Witkowski, Marcin

    2008-02-01

    In this paper a concept of a Internet Virtual Studio as a modern system for production of news, entertainment, educational and training material is proposed. This system is based on virtual studio technology and integrated with multimedia data base. Its was developed for web television content production. In successive subentries the general system architecture, as well as the architecture of modules one by one is discussed. The authors describe each module by presentation of a brief information about work principles and technical limitations. The presentation of modules is strictly connected with a presentation of their capabilities. Results produced by each of them are shown in the form of exemplary images. Finally, exemplary short production is presented and discussed.

  13. The DELLA Protein SLR1 Integrates and Amplifies Salicylic Acid- and Jasmonic Acid-Dependent Innate Immunity in Rice1

    PubMed Central

    De Vleesschauwer, David; Seifi, Hamed Soren; Haeck, Ashley; Huu, Son Nguyen; Demeestere, Kristof

    2016-01-01

    Gibberellins are a class of tetracyclic plant hormones that are well known to promote plant growth by inducing the degradation of a class of nuclear growth-repressing proteins, called DELLAs. In recent years, GA and DELLAs are also increasingly implicated in plant responses to pathogen attack, although our understanding of the underlying mechanisms is still limited, especially in monocotyledonous crop plants. Aiming to further decipher the molecular underpinnings of GA- and DELLA-modulated plant immunity, we studied the dynamics and impact of GA and DELLA during infection of the model crop rice (Oryza sativa) with four different pathogens exhibiting distinct lifestyles and infection strategies. Opposite to previous findings in Arabidopsis (Arabidopsis thaliana), our findings reveal a prominent role of the DELLA protein Slender Rice1 (SLR1) in the resistance toward (hemi)biotrophic but not necrotrophic rice pathogens. Moreover, contrary to the differential effect of DELLA on the archetypal defense hormones salicylic acid (SA) and jasmonic acid (JA) in Arabidopsis, we demonstrate that the resistance-promoting effect of SLR1 is due at least in part to its ability to boost both SA- and JA-mediated rice defenses. In a reciprocal manner, we found JA and SA treatment to interfere with GA metabolism and stabilize SLR1. Together, these findings favor a model whereby SLR1 acts as a positive regulator of hemibiotroph resistance in rice by integrating and amplifying SA- and JA-dependent defense signaling. Our results highlight the differences in hormone defense networking between rice and Arabidopsis and underscore the importance of GA and DELLA in molding disease outcomes. PMID:26829979

  14. Studio with a view

    NASA Astrophysics Data System (ADS)

    Hoover, Anthony K.

    2003-04-01

    Berklee College of Music (in Boston) needed a new studio in which to teach stereo mixing and critical listening. A small synthesis lab (adjacent to the main lobby, directly over the cafeteria kitchen, penetrated by exhaust ducts, and next to a bathroom) was chosen for renovation. The primary requirements were for maximum visibility to assure hopeful future engineers a full view of all the cool gear, and comfortable seating for fifteen students. The challenges, to be discussed, included isolation with a view, quiet HVAC, and great sound, in a space that was acoustically too small and in the wrong place. The best verification of success is its popularity, which has prevented the author from booking time for listening or testing.

  15. 76 FR 14698 - Raleigh Film and Television Studios, LLC, Los Angeles, CA; Notice of Negative Determination on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-17

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-72,587] Raleigh Film and... Reconsideration for the workers and former workers of Raleigh Film and Television Studios, LLC, Los Angeles... for reconsideration alleges that the subject firm is building large film studios in foreign countries...

  16. DELLAs Regulate Chlorophyll and Carotenoid Biosynthesis to Prevent Photooxidative Damage during Seedling Deetiolation in Arabidopsis[C][W

    PubMed Central

    Cheminant, Soizic; Wild, Michael; Bouvier, Florence; Pelletier, Sandra; Renou, Jean-Pierre; Erhardt, Mathieu; Hayes, Scott; Terry, Matthew J.; Genschik, Pascal; Achard, Patrick

    2011-01-01

    In plants, light represents an important environmental signal that triggers the production of photosynthetically active chloroplasts. This developmental switch is critical for plant survival because chlorophyll precursors that accumulate in darkness can be extremely destructive when illuminated. Thus, plants have evolved mechanisms to adaptively control plastid development during the transition into light. Here, we report that the gibberellin (GA)-regulated DELLA proteins play a crucial role in the formation of functional chloroplasts during deetiolation. We show that Arabidopsis thaliana DELLAs accumulating in etiolated cotyledons derepress chlorophyll and carotenoid biosynthetic pathways in the dark by repressing the transcriptional activity of the phytochrome-interacting factor proteins. Accordingly, dark-grown GA-deficient ga1-3 mutants (that accumulate DELLAs) display a similar gene expression pattern to wild-type seedlings grown in the light. Consistent with this, ga1-3 seedlings accumulate higher amounts of protochlorophyllide (a phototoxic chlorophyll precursor) in darkness but, surprisingly, are substantially more resistant to photooxidative damage following transfer into light. This is due to the DELLA-dependent upregulation of the photoprotective enzyme protochlorophyllide oxidoreductase (POR) in the dark. Our results emphasize the role of DELLAs in regulating the levels of POR, protochlorophyllide, and carotenoids in the dark and in protecting etiolated seedlings against photooxidative damage during initial light exposure. PMID:21571951

  17. Wisdom for Music Education from the Recording Studio

    ERIC Educational Resources Information Center

    Thibeault, Matthew D.

    2012-01-01

    Instead of focusing on the "stuff" of recording technology, this column explores ideas about the music that comes from the recording studio. Based on the author's experience working with Mark Rubel, four ideas about music are explored--one, the rise of alternatives to performance; two, the "get it done early" school of thought; three, recording as…

  18. The Iterative Design of a Virtual Design Studio

    ERIC Educational Resources Information Center

    Blevis, Eli; Lim, Youn-kyung; Stolterman, Erik; Makice, Kevin

    2008-01-01

    In this article, the authors explain how they implemented Design eXchange as a shared collaborative online and physical space for design for their students. Their notion for Design eXchange favors a complex mix of key elements namely: (1) a virtual online studio; (2) a forum for review of all things related to design, especially design with the…

  19. 32. STUDIO VIEW OF PLAQUE PLACED ON MILL HOUSE AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. STUDIO VIEW OF PLAQUE PLACED ON MILL HOUSE AT TIME OF COMPLETION, COMMEMORATING EDWARD J. LUKE (SEE TEXT) - Sperry Corn Elevator Complex, Weber Avenue (North side), West of Edison Street, Stockton, San Joaquin County, CA

  20. Group Dynamics in the Interior Design Studio: Student Perceptions

    ERIC Educational Resources Information Center

    Hill, Caroline

    2008-01-01

    This article presents the findings of a study measuring the classroom climates in collegiate interior design studios and considers these findings within the group dynamics theory framework. Three groups of students completed the College Classroom Environment Scales (CCES) questionnaire. Five of the six CCES subscale F ratios were statistically…

  1. Revealing the Experience of Children and Teachers Even in Their Absence: Documenting in the Early Childhood Studio

    ERIC Educational Resources Information Center

    Parnell, Will

    2011-01-01

    Inspired by the educational approach in the municipal pre-primary schools and infant-toddler centers of Reggio Emilia, Italy, two studio teachers and a researcher participant in Portland, Oregon capture classroom work, make investigations and interpretations in the studio as a laboratory space of learning, help children represent thinking, and…

  2. An Enhanced Studio Physics Model: Which Technologies are Productive?

    ERIC Educational Resources Information Center

    MacKinnon, Gregory R.; Williams, Peter

    2006-01-01

    The notion of problem-based physics laboratories enhanced by computer technology has been coined "studio physics" (Wilson, 1994) and has been practised at various institutions for some time (Cummings, Marx, Thornton, & Kuhl, 1999; Williams, MacLatchy, Backman, & Retson, 1997). In recent years, new technology tools have been available to supplement…

  3. The Electronic Studio and the Intranet: Network-Based Learning.

    ERIC Educational Resources Information Center

    Solis, Carlos R.

    The Electronic Studio, developed by the Rice University (Texas) Center for Technology in Teaching and Learning (CTTL), serves a number of purposes related to the construction and development of learning projects. It is a workplace, a display area, and a repository for tools, data, multimedia, design projects, and personal papers. This paper…

  4. Preparedness Portfolios and Portfolio Studios: Supporting Self-Authoring Engineers

    ERIC Educational Resources Information Center

    Sattler, Brook; Turns, Jennifer

    2015-01-01

    In this work, we engaged engineering undergraduate students in constructing an ePortfolio. The purpose of the research presented here was to explore the question, "If and in what ways do students report experiencing the construction of a preparedness portfolio in a portfolio studio as an opportunity to develop into self-authoring…

  5. Using CRISPR/Cas9 genome editing in tomato to create a gibberellin-responsive dominant dwarf DELLA allele.

    PubMed

    Tomlinson, Laurence; Yang, Ying; Emenecker, Ryan; Smoker, Matthew; Taylor, Jodie; Perkins, Sara; Smith, Justine; MacLean, Dan; Olszewski, Neil E; Jones, Jonathan D G

    2018-05-24

    The tomato PROCERA gene encodes a DELLA protein, and loss-of-function mutations derepress growth. We used CRISPR/Cas9 and a single guide RNAs (sgRNA) to target mutations to the PROCERA DELLA domain, and recovered several loss-of-function mutations and a dominant dwarf mutation that carries a deletion of one amino acid in the DELLA domain. This is the first report of a dominant dwarf PROCERA allele. This allele retains partial responsiveness to exogenously applied gibberellin (GA). Heterozygotes show an intermediate phenotype at the seedling stage, but adult heterozygotes are as dwarfed as homozygotes. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  6. The research-design interaction: lessons learned from an evidence-based design studio.

    PubMed

    Haq, Saif; Pati, Debajyoti

    2010-01-01

    As evidence-based design (EBD) emerges as a model of design practice, considerable attention has been given to its research component. However, this overshadows another essential component of EBD-the change agent, namely the designer. EBD introduced a new skill set to the practitioner: the ability to interact with scientific evidence. Industry sources suggest adoption of the EBD approach across a large number of design firms. How comfortable are these designers in integrating research with design decision making? Optimizing the interaction between the primary change agent (the designer) and the evidence is crucial to producing the desired outcomes. Preliminary to examining this question, an architectural design studio was used as a surrogate environment to examine how designers interact with evidence. Twelve students enrolled in a healthcare EBD studio during the spring of 2009. A three-phase didactic structure was adopted: knowing a hospital, knowing the evidence, and designing with knowledge and evidence. Products of the studio and questionnaire responses from the students were used as the data for analysis. The data suggest that optimization of the research-design relationship warrants consideration in four domains: (1) a knowledge structure that is easy to comprehend; (2) phase-complemented representation of evidence; (3) access to context and precedence information; and (4) a designer-friendly vocabulary.

  7. 3. Historic American Buildings Survey Photo by 'The Campbell Studios', ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey Photo by 'The Campbell Studios', 1122 North 3rd Avenue, Tucson, Arizona. c. 1881 Copied for Survey through courtesy of Harry Drachman. VIEW FROM SOUTHEAST, SHOWING PRINCIPAL STRUCTURE - Mission San Cosme del Tucson, Menlo Park, Tucson, Pima County, AZ

  8. Evaluation of an Interdisciplinary Studio Experience To Teach Architecture and Construction Science Students the Design-build Project Delivery Method.

    ERIC Educational Resources Information Center

    Graham, Charles W.; Geva, Anat

    2001-01-01

    An interdisciplinary studio project involved architecture and construction students. Evaluation of the integrated studio experience found that it gave students an accurate picture of professional practice. Architecture students were made more aware of building materials, construction technology, and cost; construction science students better…

  9. Feeling and Thinking about Studio Practices: Exploring Dissonance in Semi-Structured Interviews with Students in Higher Education Music

    ERIC Educational Resources Information Center

    Burwell, Kim

    2017-01-01

    While studio-based instrumental and vocal learning is widely regarded as both important and effective in higher education music, research to date has offered little concrete information about studio practices that students have regarded as ineffective. Two recent case studies investigated what appear to be exceptional instances in which students…

  10. Ganglioneuroblastoma: Case report and review of the literature.

    PubMed

    Alessi, S; Grignani, M; Carone, L

    2011-06-01

    Neuroblastoma are among the most important tumors of extracranial origin in pediatric patients. They arise from embryonal cells involved in the development of the sympathetic nervous system, whose differentiation has been arrested [1,2]. They are the tumors most frequently diagnosed during the first decade of life. Their evolution is unpredictable, ranging from progression to spontaneous regression or maturation, and their location and metastatic potential vary. Little is known about the cause of these tumors and the risk factors associated with their development. This article describes a typical case of ganglioneuroblastoma and provides a review of the literature on this type of tumor.Sommario Il neuroblastoma è uno dei più importanti tumori pediatrici di derivazione extracranica; esso origina dalle cellule embrionali coinvolte nello sviluppo del sistema nervoso simpatico a causa di un blocco nel loro processo di differenziamento [1,2]. È la più frequente neoplasia della prima decade di vita; la sua progressione biologica è imprevedibile, regressione spontanea, maturazione a ganglioneuroma, localizzazione e metastatizzazione variabili. Poco è noto a riguardo dei fattori di rischio e della sua eziopatogenesi. Viene presentato un caso tipico di ganglioneuroblastoma e riesaminata la letteratura su questa neoplasia.

  11. Flauto: An Ethnographic Study of a Highly Successful Private Studio

    ERIC Educational Resources Information Center

    Montemayor, Mark

    2008-01-01

    This study examined the instructional settings, pedagogical techniques, interpersonal dynamics and personal characteristics of a teacher and her adolescent students in a renowned private flute studio. Using ethnographic techniques including observations and interviews, four main themes emerged that seem to contribute to the satisfaction of the…

  12. Restructuring Introductory Physics by Adapting an Active Learning Studio Model

    ERIC Educational Resources Information Center

    Gatch, Delena

    2010-01-01

    Despite efforts to engage students in the traditional lecture environment, faculty in Georgia Southern University's Physics Department became dissatisfied with lecture as the primary means of instruction. During the fall semester of 2006, our department began adapting the studio model to suit the needs of introductory calculus-based physics…

  13. Cardboard Houses with Wings: The Architecture of Alabama's Rural Studio

    ERIC Educational Resources Information Center

    Botz-Bornstein, Thorsten

    2010-01-01

    The Rural Studio, an outreach program of Auburn University, designs innovative houses for poor people living in Alabama's Hale County by using "junk" such as car windshields, carpet tiles, baled cardboard, and old license plates. The article theorizes this particular architecture in terms of Critical Regionalism, developed by…

  14. The "Accademia della Crusca" in Italy: Past and Present

    ERIC Educational Resources Information Center

    Tosi, Arturo

    2011-01-01

    An informal organisation that is becoming quite influential in the spread of Italian in Italy, as well as abroad, is the "Accademia della Crusca" which began its activities during the Renaissance, under quite different auspices. Founded in Florence in 1582-1583, this Academy was inspired by the theories of Pietro Bembo (1470-1547), a…

  15. Documenting the conversion from traditional to Studio Physics formats at the Colorado School of Mines: Process and early results

    NASA Astrophysics Data System (ADS)

    Kohl, Patrick B.; Kuo, H. Vincent; Ruskell, Todd G.

    2008-10-01

    The Colorado School of Mines (CSM) has taught its first-semester introductory physics course using a hybrid lecture/Studio Physics format for several years. Over the past year we have converted the second semester of our calculus-based introductory physics course (Physics II) to a Studio Physics format, starting from a traditional lecture-based format. In this paper, we document the early stages of this conversion in order to better understand which features succeed and which do not, and in order to develop a model for switching to Studio that keeps the time and resource investment manageable. We describe the recent history of the Physics II course and of Studio at Mines, discuss the PER-based improvements that we are implementing, and characterize our progress via several metrics, including pre/post Conceptual Survey of Electricity and Magnetism (CSEM) scores, Colorado Learning About Science Survey scores (CLASS), solicited student comments, failure rates, and exam scores.

  16. A Theoretical Framework for the Studio as a Learning Environment

    ERIC Educational Resources Information Center

    Brandt, Carol B.; Cennamo, Katherine; Douglas, Sarah; Vernon, Mitzi; McGrath, Margarita; Reimer, Yolanda

    2013-01-01

    In this article we describe a holistic, ecological framework that takes into account the surface structures and pedagogical approaches in the studio and how these elements are connected to the construction of design knowledge: epistemology. In our development of this framework, we came to understand how disciplinary underpinnings and academic…

  17. Inside the Sex Ed Studio: An Interview with Peggy Brick

    ERIC Educational Resources Information Center

    Taverner, William J.

    2008-01-01

    "Inside the Sex Ed Studio" profiles leaders in the field of sexuality education. Peggy Brick, former director of Planned Parenthood of Greater Northern New Jersey's Center for Family Life Education (CFLE) and author of numerous sexuality education resources used worldwide, is the subject of this interview. Ms. Brick was interviewed by…

  18. Ludic Toons: The Dynamics of Creative Play in Studio Animation

    ERIC Educational Resources Information Center

    Power, Pat

    2012-01-01

    Though generally accepted as the most playfully entertaining form of popular media or art, animation as play has received little scholarly analysis. The author examines the nature of playfulness in animation and describes play as a critical tool in animation studies. Examining studio character animation from such perspectives as creative…

  19. The Problem Solving Studio: An Apprenticeship Environment for Aspiring Engineers

    ERIC Educational Resources Information Center

    Le Doux, Joseph M.; Waller, Alisha A.

    2016-01-01

    This paper describes the problem-solving studio (PSS) learning environment. PSS was designed to teach students how to solve difficult analytical engineering problems without resorting to rote memorization of algorithms, while at the same time developing their deep conceptual understanding of the course topics. There are several key features of…

  20. Curiositas and Studiositas: Investigating Student Curiosity and the Design Studio

    ERIC Educational Resources Information Center

    Smith, Korydon

    2011-01-01

    Curiosity is often considered the foundation of learning. There is, however, little understanding of how (or if) pedagogy in higher education affects student curiosity, especially in the studio setting of architecture, interior design and landscape architecture. This article provides a brief cultural history of curiosity and its role in the design…

  1. Group Projects in Interior Design Studio Classes: Peer Feedback Benefits

    ERIC Educational Resources Information Center

    Jurado, Juan A.

    2011-01-01

    Group projects have been shown to be effective for providing peer feedback in classrooms. While students in regular enrollment classes benefit from peer feedback, low-enrollment classes face many challenges. This study compares peer feedback effectiveness between two interior design studio classes with different design projects. In one class,…

  2. Integrating the Engineering Curriculum through the Synthesis and Design Studio

    ERIC Educational Resources Information Center

    Kellam, Nadia; Walther, Joachim; Costantino, Tracie; Cramond, Bonnie

    2013-01-01

    Traditional curricular approaches within engineering education tend to be fragmented, with opportunities for content- and meta-level synthesis being mostly limited to freshman and senior year design courses. In this paper, we are proposing a curricular model, the Synthesis and Design Studio, to combat the tendency towards fragmented curricula. The…

  3. Design and Implementation of a Studio-Based General Chemistry Course

    ERIC Educational Resources Information Center

    Gottfried, Amy C.; Sweeder, Ryan D.; Bartolin, Jeffrey M.; Hessler, Jessica A.; Reynolds, Benjamin P.; Stewart, Ian C.; Coppola, Brian P.; Holl, Mark Banaszak M.

    2007-01-01

    The design and implementation of a new value-added general chemistry course, which could use the studio instructional method to incorporate the existing educational research is reviewed. These teaching methods and activities were woven into the course to provide the students with ways of learning chemical concepts and practicing scientific…

  4. A Pivotal Role of DELLAs in Regulating Multiple Hormone Signals.

    PubMed

    Davière, Jean-Michel; Achard, Patrick

    2016-01-04

    Plant phenotypic plasticity is controlled by diverse hormone pathways, which integrate and convey information from multiple developmental and environmental signals. Moreover, in plants many processes such as growth, development, and defense are regulated in similar ways by multiple hormones. Among them, gibberellins (GAs) are phytohormones with pleiotropic actions, regulating various growth processes throughout the plant life cycle. Previous work has revealed extensive interplay between GAs and other hormones, but the molecular mechanism became apparent only recently. Molecular and physiological studies have demonstrated that DELLA proteins, considered as master negative regulators of GA signaling, integrate multiple hormone signaling pathways through physical interactions with transcription factors or regulatory proteins from different families. In this review, we summarize the latest progress in GA signaling and its direct crosstalk with the main phytohormone signaling, emphasizing the multifaceted role of DELLA proteins with key components of major hormone signaling pathways. Copyright © 2016 The Author. Published by Elsevier Inc. All rights reserved.

  5. Engagement studios: students and communities working to address the determinants of health.

    PubMed

    Bainbridge, Lesley; Grossman, Susan; Dharamsi, Shafik; Porter, Jill; Wood, Victoria

    2014-01-01

    This article presents an innovative model for interprofessional community-oriented learning. The Engagement Studios model involves a partnership between community organizations and students as equal partners in conversations and activities aimed at addressing issues of common concern as they relate to the social determinants of health. Interprofessional teams of students from health and non-health disciplines work with community partners to identify priority community issues and explore potential solutions. The student teams work with a particular community organization, combining their unique disciplinary perspectives to develop a project proposal, which addresses the community issues that have been jointly identified. Approved proposals receive a small budget to implement the project. In this paper we present the Engagement Studios model and share lessons learned from a pilot of this educational initiative.

  6. Lost in Translation: Reconsidering Reflective Practice and Design Studio Pedagogy

    ERIC Educational Resources Information Center

    Mewburn, Inger

    2012-01-01

    Drawing on empirical research done in the early 1980s, Donald Schon developed the theory of "reflective practice", putting forward the idea that the design studio teacher is a "coach" who helps students align with disciplinary norms and start to "think like an architect". Drawing on actor-network theory as a tool of…

  7. The "Tutorless" Design Studio: A Radical Experiment in Blended Learning

    ERIC Educational Resources Information Center

    Hill, Glen Andrew

    2017-01-01

    This paper describes a pedagogical experiment in which a suite of novel blended learning strategies was used to replace the traditional role of design tutors in a first year architectural design studio. The pedagogical objectives, blended learning strategies and outcomes of the course are detailed. While the quality of the student design work…

  8. Studio in Advertising Design, Fashion Design and Illustration, Product Design, Stage Design. Volume 3: Advanced Elective Courses in Art for Grades 10, 11, or 12.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Bureau of Secondary Curriculum Development.

    The document provides teaching guidelines and information on advance elective courses in a studio art program for grades 10, 11, and 12. The courses are presented in four sections: (1) studio in advertising design--advertising and production, lettering, illustrating, and color reproduction; (2) studio in fashion design and illustration--elements…

  9. Critical Perspectives of Technology-Enhanced Learning in Relation to Specialist Communication Design Studio Education within the UK and Australia

    ERIC Educational Resources Information Center

    Marshalsey, Lorraine; Sclater, Madeleine

    2018-01-01

    This paper investigates the widespread integration of technology-enhanced learning (TEL) within specialist Communication Design studio education in the UK and Australia. The impetus for this paper has grown from the challenges facing day-to-day design studio education and the recognition that the use of technology in higher education today has…

  10. Attitudes toward drinking conveyed in studio greeting cards.

    PubMed Central

    Finn, P

    1980-01-01

    Analysis of 129 studio cards containing alcohol-related subject matter revealed themes which suggest that getting drunk is a natural and desirable concomitant of celebrations and that drunkenness is humorous, enjoyable, and harmless. It is proposed that the depiction of intoxication in these cards as pleasurable and risk-free may legitimate and reinforce tolerant attitudes toward alcohol abuse and thereby contribute to their entrenchment and pervasiveness in the face of recent public education prevention campaigns. PMID:7416343

  11. Managing the Complexity of Design Problems through Studio-Based Learning

    ERIC Educational Resources Information Center

    Cennamo, Katherine; Brandt, Carol; Scott, Brigitte; Douglas, Sarah; McGrath, Margarita; Reimer, Yolanda; Vernon, Mitzi

    2011-01-01

    The ill-structured nature of design problems makes them particularly challenging for problem-based learning. Studio-based learning (SBL), however, has much in common with problem-based learning and indeed has a long history of use in teaching students to solve design problems. The purpose of this ethnographic study of an industrial design class,…

  12. Music Instrument Teachers in Higher Education: An Investigation of the Key Influences on How They Teach in the Studio

    ERIC Educational Resources Information Center

    Daniel, Ryan; Parkes, Kelly A.

    2017-01-01

    In higher education music instrument teaching, there is a strong tradition of high-level performers being recruited to teach advanced students within the private studio despite the fact these educators often have no training in pedagogy. The studio environment also continues to be dominated by the one-to-one lesson format and the master-apprentice…

  13. Reflections on the Evolving Triad Tutorial in a Postgraduate Art Studio

    ERIC Educational Resources Information Center

    Tripp, Sarah

    2016-01-01

    This article traces the evolution of the "triad tutorial". The triad model, predominantly used in the training of counsellors and psychotherapists, was originally combined with the art school tutorial model in the context of the Edinburgh Sculpture Workshop to enhance critical discourse between studio holders. The resulting hybrid, the…

  14. The Lure of Non-Credit Studio Art Classes for Adult Learners

    ERIC Educational Resources Information Center

    Murray, Gina C.

    2012-01-01

    The purpose of this study was to examine the motivation and satisfaction of adult learners who participated in non-credit studio art classes. Leisure motivation has been researched by educators, philosophers, psychologists, and social scientists (Candy, 1991; Brookfield, 2005: Dewey, 1980; Knowles, 1998; Maslow, 1970; Rogers, 1961, Stebbins,…

  15. Jungle Quest: Adventures in Creating a HyperStudio Word Study Program.

    ERIC Educational Resources Information Center

    Ludwig, Jessica; Green, Lauren

    This paper describes the development, design, and implementation of an educational multimedia program. The program, "Jungle Quest," combined HyperStudio and word study in a game for classroom use. Methods for word study provide a carefully sequenced teaching of phonics, vocabulary, and spelling following children's natural stages of…

  16. Boat Building Design and Construction Techniques in the Architectural Design Studio.

    ERIC Educational Resources Information Center

    Smith, Richard A.

    1982-01-01

    Describes a model boat building project for architectural design studios. Working from traditional sailboat designs, students study the "lines" drawings of boats, make full-size drawings from scale drawings, and then construct model wooden boats. Available from Carfax Publishing Company, P.O. Box 25, Abindgon, Oxfordshire OX14 1RW…

  17. Fostering Teacher Learning of Conjecturing, Generalising and Justifying through Mathematics Studio

    ERIC Educational Resources Information Center

    Lesseig, Kristin

    2016-01-01

    Calls to advance students' ability to engage in mathematical reasoning practices including conjecturing, generalising and justifying (CGJ) place significant new demands on teachers. This case study examines how Mathematics Studio provided opportunities for a team of U.S. middle school teachers to learn about these practices and ways to promote…

  18. International Conference on Organometallic Chemistry (13th) Held in Torino, Europe on 4-9 September 1988. Abstracts

    DTIC Science & Technology

    1988-09-09

    On Synthesis Of Dialkyl d-Trimethylsilyloxyalkylphosphonates Zhao Yong-Zhen and Li Zhong- Rua Dpartment o chemistry, Hua Zhong Normal University, Wuhan...Jose Vicente. Jose-AntelC hAd. Na-Yeij~xa Qhicote. Ju~an-Francisco Gutliez-Jugo. Carmen Ramirez do Arel lano. Departamento do Oulmica InordanIca...Peruzzini, Jos& Antonio Ramirez , Alberto Vacca, Francesco Vizza and Fabrizio Zanobini, Istituto per lo Studio della Stereochimica ed Energetica dei

  19. Stretch and Studio Composition Practicum: Creating a Culture of Support and Success for Developing Writers at a Hispanic-Serving Institution

    ERIC Educational Resources Information Center

    Elder, Cristyn L.; Davila, Bethany

    2017-01-01

    This course design describes a 3-credit, two-week intensive Stretch and Studio Practicum course at the University of New Mexico (UNM). Because the Stretch and Studio composition curriculum is designed to help students who may be at greater risk of not succeeding, instructors are required to complete the practicum before teaching in the program.…

  20. Inside the Actors' Studio: Exploring Dietetics Education Practices through Dialogical Inquiry

    ERIC Educational Resources Information Center

    Fox, Ann L.; Gingras, Jacqui

    2012-01-01

    Two colleagues, Ann and Jacqui, came together, within the safety of an imagined actors' studio, to explore the challenges that Ann faced in planning a new graduate program in public health nutrition. They met before, during, and after program implementation to discuss Ann's experiences, and audio-taped and transcribed the discussions. When all…

  1. Using Active Learning in a Studio Classroom to Teach Molecular Biology

    ERIC Educational Resources Information Center

    Nogaj, Luiza A.

    2013-01-01

    This article describes the conversion of a lecture-based molecular biology course into an active learning environment in a studio classroom. Specific assignments and activities are provided as examples. The goal of these activities is to involve students in collaborative learning, teach them how to participate in the learning process, and give…

  2. Carnegie Mellon's STUDIO for Creative Inquiry [and] The Interdisciplinary Teaching Network (ITeN) [and] Interactive Fiction [and] The Networked Virtual Art Museum.

    ERIC Educational Resources Information Center

    Holden, Lynn; And Others

    1992-01-01

    Explains the STUDIO for Creative Inquiry, an interdisciplinary center at Carnegie Mellon University that supports experimental activities in the arts, and its Interdisciplinary Teaching Network. Three STUDIO projects are described: the Ancient Egypt Prototype application of the network; an interactive fiction system based on artificial…

  3. Designing Teaching--Teaching Designing: Teacher's Guidance in a Virtual Design Studio

    ERIC Educational Resources Information Center

    Lahti, Henna; Seitamaa-Hakkarainen, Pirita

    2014-01-01

    This study examined pedagogical aspects of virtual designing. It focused on how an industrial design teacher organised a university course in plastic product design and how the teacher guided student teams' design processes in a virtual design studio. The model of Learning by Collaborative Design was used as a pedagogical and analytical framework.…

  4. Scrutinizing Studio Art and Its Study: Historical Relations and Contemporary Conditions

    ERIC Educational Resources Information Center

    Grierson, Elizabeth M.

    2010-01-01

    This article addresses shifts in the pedagogical positioning of art theory and art practice through the decades of the 1980s, 1990s, and 2000s and considers how shifts to postdisciplinarity might inform practices in the art academy today. It considers legacies of modernity to disclose methodological and ideological scaffolds upon which studio art…

  5. 'Overgrowth' mutants in barley and wheat: new alleles and phenotypes of the 'Green Revolution' DELLA gene.

    PubMed

    Chandler, Peter Michael; Harding, Carol Anne

    2013-04-01

    A suppressor screen using dwarf mutants of barley (Hordeum vulgare L.) led to the isolation of 'overgrowth' derivatives, which retained the original dwarfing gene but grew at a faster rate because of a new mutation. The new mutations were in the Slender1 (Sln1) gene (11/13 cases), which encodes the DELLA protein central to gibberellin (GA) signalling, showed 100% genetic linkage to Sln1 (1/13), or were in the Spindly1 (Spy1) gene (1/13), which encodes another protein involved in GA signalling. The overgrowth mutants were characterized by increased GA signalling, although the extent still depended on the background GA biosynthesis capacity, GA receptor function, and DELLA activity. A comparison between two GA responses, α-amylase production and leaf growth rate, revealed degrees of specificity for both the overgrowth allele and the GA response under consideration. Many overgrowth mutants were also isolated in a dwarf line of bread wheat (Triticum aestivum L.) and 19 new alleles were identified in the Rht-B1 gene, one of the 'Green Revolution' semi-dwarfing genes and the orthologue of Sln1. The sites of amino acid substitutions in the DELLA proteins of both species provide insight into DELLA function, and included examples where identical but independent substitutions were observed. In both species, the starting lines were too dwarfed to be directly useful in breeding programmes, but new overgrowth derivatives with semidwarf heights have now been characterized. The variation they exhibit in GA-influenced traits identifies novel alleles with perfect markers that are of potential use in breeding.

  6. College Teachers' Thinking and Planning: A Qualitative Study in the Design Studio.

    ERIC Educational Resources Information Center

    Dinham, Sarah M.

    This study is concerned with teaching in an apprenticeship setting--the architectural design studio. The research examined teachers' planning, particularly as it focuses upon project assignments. The study yielded information about teachers' conceptual frames for their teaching, the personal aspects of teaching, the teachers' conceptions of…

  7. Speakeasy Studio and Cafe: Information Literacy, Web-based Library Instruction, and Technology.

    ERIC Educational Resources Information Center

    Jacobs, Mark

    2001-01-01

    Discussion of academic library instruction and information literacy focuses on a Web-based program developed at Washington State University called Speakeasy Studio and Cafe that is used for bibliographic instruction. Highlights include the research process; asking the right question; and adapting to students' differing learning styles. (LRW)

  8. Maximum performance synergy: A new approach to recording studio control room design

    NASA Astrophysics Data System (ADS)

    Szymanski, Jeff D.

    2003-10-01

    Popular recording studio control room designs include LEDE(tm), RFZ(tm), and nonenvironment rooms. The common goal of all of these is to create an accurate acoustical environment that does not distort or otherwise color audio reproduction. Also common to these designs is the frequent need to have multiple ancillary recording rooms, often adjacent to the main control room, where group members perform. This approach, where group members are physically separated from one another, can lead to lack of ensemble in the finished recordings. New twists on old acoustical treatment techniques have been implemented at a studio in Nashville, Tennessee, which minimize the need for multiple ancillary recording rooms, thus creating an environment where talent, producer and recording professionals can all occupy the same space for maximum performance synergy. Semi-separated performance areas are designed around a central, critical listening area. The techniques and equipment required to achieve this separation are reviewed, as are advantages and disadvantages to this new control room design approach.

  9. Crossing Boundaries: Sharing Concepts of Music Teaching from Classroom to Studio

    ERIC Educational Resources Information Center

    McPhail, Graham J.

    2010-01-01

    This study demonstrates how action research can provide a means for teachers to undertake research for themselves to inform and enhance their work. The focus of the research was the self-critique of pedagogical practice in one-to-one classical instrumental music teaching within the context of the author's private studio. A series of lessons were…

  10. mzStudio: A Dynamic Digital Canvas for User-Driven Interrogation of Mass Spectrometry Data.

    PubMed

    Ficarro, Scott B; Alexander, William M; Marto, Jarrod A

    2017-08-01

    Although not yet truly 'comprehensive', modern mass spectrometry-based experiments can generate quantitative data for a meaningful fraction of the human proteome. Importantly for large-scale protein expression analysis, robust data pipelines are in place for identification of un-modified peptide sequences and aggregation of these data to protein-level quantification. However, interoperable software tools that enable scientists to computationally explore and document novel hypotheses for peptide sequence, modification status, or fragmentation behavior are not well-developed. Here, we introduce mzStudio, an open-source Python module built on our multiplierz project. This desktop application provides a highly-interactive graphical user interface (GUI) through which scientists can examine and annotate spectral features, re-search existing PSMs to test different modifications or new spectral matching algorithms, share results with colleagues, integrate other domain-specific software tools, and finally create publication-quality graphics. mzStudio leverages our common application programming interface (mzAPI) for access to native data files from multiple instrument platforms, including ion trap, quadrupole time-of-flight, Orbitrap, matrix-assisted laser desorption ionization, and triple quadrupole mass spectrometers and is compatible with several popular search engines including Mascot, Proteome Discoverer, X!Tandem, and Comet. The mzStudio toolkit enables researchers to create a digital provenance of data analytics and other evidence that support specific peptide sequence assignments.

  11. Further Adventures of Dr. Sony's Mad Monster Machine, or Cutting the Studio Umbilical Cord

    ERIC Educational Resources Information Center

    Steffin, Sherwin

    1977-01-01

    We must reexamine our often total reliance on the studio as the only source for instructional television production. The porta-pak provides an alternative. Tips are provided for successful field production. (Author/STS)

  12. DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6.

    PubMed

    Zhang, Yongqiang; Liu, Zhongjuan; Wang, Xiaoyun; Wang, Jianfeng; Fan, Kai; Li, Zhaowei; Lin, Wenxiong

    2018-03-24

    DELLA proteins' negative regulation of dark-induced senescence and chlorophyll degradation in Arabidopsis is through interaction with WRKY6 and thus repression of its transcriptional activities on senescence-related genes. Senescence is an intricate and highly orchestrated process regulated by numerous endogenous and environmental signals. Gibberellins (GAs) and their signaling components DELLA proteins have been known to participate in the regulation of senescence. However, the mechanism of the GA-DELLA system involved in the senescence process remains largely unclear. Darkness is a known environmental factor that induces plant senescence. In this study, exogenous GA 3 (an active form of GA) accelerated but paclobutrazol (a specific GA biosynthesis inhibitor) retarded dark-induced leaf yellowing in Arabidopsis. Moreover, the dark-triggered decrease in chlorophyll content, increase in cell membrane leakage, and upregulation of senescence-associated genes were notably impaired in both endogenous GA-decreased mutants ga3ox1/ga3ox2 and ga20ox1/ga20ox2 compared with those in wild-type Col-0. These effects of darkness were enhanced in the quintuple mutant of DELLA genes gai-t6/rga-t2/rgl1-1/rgl2-1/rgl3-1 and conversely attenuated in the gain-of-function mutant gai and transgenic plant 35S::TAP-RGAd17 compared with wild-type Ler. Subsequently, RGA interacted with the transcription factor WRKY6 in a yeast two-hybrid assay, as confirmed by bimolecular fluorescence complementation and pull-down analyses. In addition, mutation and overexpression of WRKY6 retarded and accelerated dark-induced senescence, respectively. Furthermore, transient expression assays in Arabidopsis protoplasts indicated that RGA and GAI weakened the transcriptional activities of WRKY6 on its downstream senescence-related genes, including SAG13 and SGR. Taken together, these results suggest that GAs positively and DELLAs negatively regulate dark-induced senescence and chlorophyll degradation in

  13. Research on inosculation between master of ceremonies or players and virtual scene in virtual studio

    NASA Astrophysics Data System (ADS)

    Li, Zili; Zhu, Guangxi; Zhu, Yaoting

    2003-04-01

    A technical principle about construction of virtual studio has been proposed where orientation tracker and telemeter has been used for improving conventional BETACAM pickup camera and connecting with the software module of the host. A model of virtual camera named Camera & Post-camera Coupling Pair has been put forward, which is different from the common model in computer graphics and has been bound to real BETACAM pickup camera for shooting. The formula has been educed to compute the foreground frame buffer image and the background frame buffer image of the virtual scene whose boundary is based on the depth information of target point of the real BETACAM pickup camera's projective ray. The effect of real-time consistency has been achieved between the video image sequences of the master of ceremonies or players and the CG video image sequences for the virtual scene in spatial position, perspective relationship and image object masking. The experimental result has shown that the technological scheme of construction of virtual studio submitted in this paper is feasible and more applicative and more effective than the existing technology to establish a virtual studio based on color-key and image synthesis with background using non-linear video editing technique.

  14. AP Studio Art as an Enabling Constraint for Secondary Art Education

    ERIC Educational Resources Information Center

    Graham, Mark A.

    2009-01-01

    Advanced Placement (AP) Studio Art is an influential force in secondary art education as is evident in the 31,800 portfolios submitted for review in 2008. From the perspectives of a high school educator and AP Reader, this author has observed how the constraints of the AP program can be used to generate support for high school art programs and…

  15. The National Film Board's Studio D: Feminists Making Films for Peace.

    ERIC Educational Resources Information Center

    Taylor, Anita

    Studio D of the National Film Board of Canada, a women's film making unit established to make films by, for, and about women, has created a group of five films that effectively develop the argument that women can and must join the effort to bring peace to a nuclear world. The first of these peace films, "If You Love This Planet,"…

  16. Mechatronics Learning Studio: From "Play and Learn" to Industry-Inspired Green Energy Applications

    ERIC Educational Resources Information Center

    Habash, R. W. Y.; Suurtamm, C.; Necsulescu, D.

    2011-01-01

    This paper describes the evolution of the teaching of electrical engineering to mechanical engineering students based on motivation and a pedagogical strategy incorporating interdisciplinary mechatronics projects in a learning studio environment. Implementation of student projects within the curriculum has been demonstrated to be highly…

  17. Interest-Driven Learning Among Middle School Youth in an Out-of-School STEM Studio

    NASA Astrophysics Data System (ADS)

    Evans, Michael A.; Lopez, Megan; Maddox, Donna; Drape, Tiffany; Duke, Rebekah

    2014-10-01

    The concept of connected learning proposes that youth leverage individual interest and social media to drive learning with an academic focus. To illustrate, we present in-depth case studies of Ryan and Sam, two middle-school-age youth, to document an out-of-school intervention intended to direct toward intentional learning in STEM that taps interest and motivation. The investigation focused on how Ryan and Sam interacted with the designed elements of Studio STEM and whether they became more engaged to gain deeper learning about science concepts related to energy sustainability. The investigation focused on the roles of the engineering design process, peer interaction, and social media to influence youth interest and motivation. Research questions were based on principles of connected learning (e.g., self-expression, lower barriers to expertise, socio-technical supports) with data analyzed within a framework suggested by discursive psychology. Analyzing videotaped excerpts of interactions in the studio, field notes, interview responses, and artifacts created during the program resulted in the following findings: problem solving, new media, and peer interaction as designed features of Studio STEM elicited evidence of stimulating interest in STEM for deeper learning. Further research could investigate individual interest-driven niches that are formed inside the larger educational setting, identifying areas of informal learning practice that could be adopted in formal settings. Moreover, aspects of youth's STEM literacy that could promote environmental sustainability through ideation, invention, and creativity should be pursued.

  18. The City at Play: "Second Life" and the Virtual Urban Planning Studio

    ERIC Educational Resources Information Center

    Thomas, David; Hollander, Justin B.

    2010-01-01

    This study interrogates the idea of using videogames and game-like virtual worlds as a means to advance studio education pedagogy. Looking at a series of case studies of urban planning courses taught using "Second Life," the results describe the potentials, and limits, of this emerging digital media. Key findings are that the virtual worlds…

  19. The Intentional Use of Learning Management Systems (LMS) to Improve Outcomes in Studio

    ERIC Educational Resources Information Center

    MacKenzie, Andrew; Muminovic, Milica; Oerlemans, Karin

    2017-01-01

    At the University of Canberra, Australia, the design and architecture faculty are trialling a range of approaches to incorporating learning technologies in the first year foundation studio to improve student learning outcomes. For this study researchers collected information on students' access to their assignment information and feedback from the…

  20. A Socio-Cognitive Approach to Knowledge Construction in Design Studio through Blended Learning

    ERIC Educational Resources Information Center

    Kocaturk, Tuba

    2017-01-01

    This paper results from an educational research project that was undertaken by the School of Architecture, at the University of Liverpool funded by the Higher Education Academy in UK. The research explored technology driven shifts in architectural design studio education, identified their cognitive effects on design learning and developed an…

  1. A "Knowledge Trading Game" for Collaborative Design Learning in an Architectural Design Studio

    ERIC Educational Resources Information Center

    Wang, Wan-Ling; Shih, Shen-Guan; Chien, Sheng-Fen

    2010-01-01

    Knowledge-sharing and resource exchange are the key to the success of collaborative design learning. In an architectural design studio, design knowledge entails learning efforts that need to accumulate and recombine dispersed and complementary pieces of knowledge. In this research, firstly, "Knowledge Trading Game" is proposed to be a way for…

  2. [Assessment of a project for integrated management of care given to patients with type-2 diabetes in the Local Health Authority 21 of Legnago (Veneto Region, Northern Italy) in the period 2010-2012].

    PubMed

    Marcon, Alessandro; Vaona, Alberto; Rigon, Giulio; Carazzolo, Marco; Del Zotti, Franco; Girotto, Sandro; Marafetti, Claudio

    2016-01-01

    OBIETTIVI: descrivere, nella ASL 21 di Legnago (VR), l'andamento di alcuni indicatori sanitari tra il 2009, anno precedente all'avvio di un progetto triennale per la gestione integrata dell'assistenza al paziente con diabete mellito di tipo 2, e il 2012, ultimo anno del progetto. DISEGNO: studio longitudinale trasversale ripetuto. SETTING E PARTECIPANTI: tutti i pazienti diabetici di tipo 2 della ASL 21, identificati nei database aziendali (in base a esenzioni per patologia, accessi al servizio diabetologico, consumo di farmaci antidiabetici e strisce per la determinazione della glicemia) e nelle cartelle cliniche dei medici di famiglia. PRINCIPALI MISURE DI OUTCOME: numero di test diagnostici e di follow-up erogati, consumo di farmaci, prestazioni specialistiche, accessi al pronto soccorso, ricoveri e mortalità. RISULTATI: nonostante un calo generalizzato (-3,1%) nei test erogati dalla ASL 21 ai suoi assistititi nel periodo 2009-2012, l'analisi ha documentato un marcato aumento per gli esami previsti nella gestione del diabete, quali curve da carico glicemico (+104,3%), emoglobina glicata (+19,0%) e microalbuminuria (+296,1%). I soggetti identificati come diabetici sono aumentati da 8.084 nel 2009 (5,2%) a 9.221 nel 2012 (5,9%). Sono stati osservati aumenti nella prevalenza di pazienti visitati presso un servizio diabetologico (dal 22,6% al 39,0%), nonché negli utilizzatori di metformina (dal 28,0% al 37,5%), insuline (dal 13,5% al 18,3%) e incretine (dall'1,4% al 9,0%). Il consumo di sulfaniluree è, invece, calato (dal 49,9% al 40,8%), come anche l'erogazione di alcune prestazioni specialistiche, gli accessi al pronto soccorso e i ricoveri, mentre il tasso di mortalità è rimasto stabile (29,6 decessi x1.000/anno). CONCLUSIONE: durante il periodo di implementazione del progetto sembra essersi verificato un aumento della sensibilità diagnostica e una maggiore presa in carico del paziente diabetico. Anche se la natura osservazionale dello studio non consente

  3. Improving Student Commitment to Healthcare-Related Design Practice by Improving the Studio Learning Experience.

    PubMed

    Tan, Lindsay; Hong, Miyoung; Albert, Taneshia West

    2017-10-01

    This case study explores the influence of the healthcare design studio experience on students' short-term professional goals as measured through rates of healthcare-related certification and internship/employment. The value and relevance of interior design is evident in the healthcare design sector. However, interior design students may not perceive this value if it is not communicated through their design education. Students' experience in the design studio plays a crucial role in determining career choices, and students may be more committed to career goals when there is clear connection between major coursework and professional practice. The authors compared healthcare-related certification and internship/employment levels between two student cohorts in a capstone undergraduate interior design healthcare design studio course. The first cohort was led by the existing curriculum. The second cohort was led by the revised curriculum that specifically aimed at encouraging students to commit to healthcare-related design practice. When measured at 3 months from graduation, the second cohort, led by the revised curriculum, saw a 30% increase in Evidence-based Design Accreditation and Certification exam pass rates and a 40% increase in healthcare-related internship/employment. The challenge of interior design education is to instill in emerging professionals not only professional competence but also those professional attitudes that will make them better prepared to design spaces that improve quality of life, particularly in healthcare environments. The results exceeded the project goals, and so this could be considered a promising practice for courses focused on healthcare design education.

  4. [The Istituto di Storia della Medicina archive and video collection].

    PubMed

    Aruta, Alessandro; De Angelis, Elio

    2006-01-01

    The Istituto di Storia della Medicina at Rome University was to a certain extent a one-man achievement. Founded by Adalberto Pazzini in 1937, its collections comprehended books, objects, as well as photographs, movies, and other didactic video. The Istituto was also a center for publications, conferences and meetings. The archival sources that document its activity have been re-evaluated and restored in recent years, together with the collections housed in the Library and in the Museum.

  5. The integration of studio cycling into a worksite stress management programme.

    PubMed

    Clark, Matthew M; Soyring, Jason E; Jenkins, Sarah M; Daniels, Denise C; Berkland, Bridget E; Werneburg, Brooke L; Hagen, Philip T; Lopez-Jimenez, Francisco; Warren, Beth A; Olsen, Kerry D

    2014-04-01

    High stress is a prevalent problem in the worksite. To reduce stress, improve productivity, reduce absenteeism, and lower healthcare costs, many companies offer exercise classes or stress management programmes. Although physical activity is an important component of stress management, few worksites have integrated physical activity into their comprehensive stress reduction programmes. The purpose of this single-arm pilot project was to examine the potential effectiveness of an integrated exercise (studio cycling) and cognitive-behavioural stress management programme. Eighty-four adults, 75% female, mostly aged 40+ years, participated in an integrated 12-week cycling studio and cognitive-behavioural stress management programme. Participants experienced a significant and clinically meaningful reduction on the Perceived Stress Scale (p < 0.01), rating of current stress level and confidence to manage stress at the programme's end and at a 1-month follow-up. Participants also reported having significantly improved overall health, improved nutritional habits, higher physical activity level, greater confidence in their ability to follow a healthy diet, higher spiritual well-being, improved sleep, receiving more support for maintaining healthy living and improved quality of life at the completion of the 12-week programme and 1-month follow-up. These findings provide further support for an integrated exercise and stress management programme. © 2013 John Wiley & Sons, Ltd.

  6. OpenStudio: A Platform for Ex Ante Incentive Programs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roth, Amir; Brackney, Larry; Parker, Andrew

    Many utilities operate programs that provide ex ante (up front) incentives for building energy conservation measures (ECMs). A typical incentive program covers two kinds of ECMs. ECMs that deliver similar savings in different contexts are associated with pre-calculated 'deemed' savings values. ECMs that deliver different savings in different contexts are evaluated on a 'custom' per-project basis. Incentive programs often operate at less than peak efficiency because both deemed ECMs and custom projects have lengthy and effort-intensive review processes--deemed ECMs to gain confidence that they are sufficiently context insensitive, custom projects to ensure that savings are claimed appropriately. DOE's OpenStudio platformmore » can be used to automate ex ante processes and help utilities operate programs more efficiently, consistently, and transparently, resulting in greater project throughput and energy savings. A key concept of the platform is the OpenStudio Measure, a script that queries and transforms building energy models. Measures can be simple or surgical, e.g., applying different transformations based on space-type, orientation, etc. Measures represent ECMs explicitly and are easier to review than ECMs that are represented implicitly as the difference between a with-ECM and without-ECM models. Measures can be automatically applied to large numbers of prototype models--and instantiated from uncertainty distributions--facilitating the large scale analysis required to develop deemed savings values. For custom projects, Measures can also be used to calibrate existing building models, to automatically create code baseline models, and to perform quality assurance screening.« less

  7. Acoustic scaling: A re-evaluation of the acoustic model of Manchester Studio 7

    NASA Astrophysics Data System (ADS)

    Walker, R.

    1984-12-01

    The reasons for the reconstruction and re-evaluation of the acoustic scale mode of a large music studio are discussed. The design and construction of the model using mechanical and structural considerations rather than purely acoustic absorption criteria is described and the results obtained are given. The results confirm that structural elements within the studio gave rise to unexpected and unwanted low-frequency acoustic absorption. The results also show that at least for the relatively well understood mechanisms of sound energy absorption physical modelling of the structural and internal components gives an acoustically accurate scale model, within the usual tolerances of acoustic design. The poor reliability of measurements of acoustic absorption coefficients, is well illustrated. The conclusion is reached that such acoustic scale modelling is a valid and, for large scale projects, financially justifiable technique for predicting fundamental acoustic effects. It is not appropriate for the prediction of fine details because such small details are unlikely to be reproduced exactly at a different size without extensive measurements of the material's performance at both scales.

  8. Development of Automated Procedures to Generate Reference Building Models for ASHRAE Standard 90.1 and India’s Building Energy Code and Implementation in OpenStudio

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Parker, Andrew; Haves, Philip; Jegi, Subhash

    This paper describes a software system for automatically generating a reference (baseline) building energy model from the proposed (as-designed) building energy model. This system is built using the OpenStudio Software Development Kit (SDK) and is designed to operate on building energy models in the OpenStudio file format.

  9. Inferring Caravaggio's studio lighting and praxis in The calling of St. Matthew by computer graphics modeling

    NASA Astrophysics Data System (ADS)

    Stork, David G.; Nagy, Gabor

    2010-02-01

    We explored the working methods of the Italian Baroque master Caravaggio through computer graphics reconstruction of his studio, with special focus on his use of lighting and illumination in The calling of St. Matthew. Although he surely took artistic liberties while constructing this and other works and did not strive to provide a "photographic" rendering of the tableau before him, there are nevertheless numerous visual clues to the likely studio conditions and working methods within the painting: the falloff of brightness along the rear wall, the relative brightness of the faces of figures, and the variation in sharpness of cast shadows (i.e., umbrae and penumbrae). We explored two studio lighting hypotheses: that the primary illumination was local (and hence artificial) and that it was distant solar. We find that the visual evidence can be consistent with local (artificial) illumination if Caravaggio painted his figures separately, adjusting the brightness on each to compensate for the falloff in illumination. Alternatively, the evidence is consistent with solar illumination only if the rear wall had particular reflectance properties, as described by a bi-directional reflectance distribution function, BRDF. (Ours is the first research applying computer graphics to the understanding of artists' praxis that models subtle reflectance properties of surfaces through BRDFs, a technique that may find use in studies of other artists.) A somewhat puzzling visual feature-unnoted in the scholarly literature-is the upward-slanting cast shadow in the upper-right corner of the painting. We found this shadow is naturally consistent with a local illuminant passing through a small window perpendicular to the viewer's line of sight, but could also be consistent with solar illumination if the shadow was due to a slanted, overhanging section of a roof outside the artist's studio. Our results place likely conditions upon any hypotheses concerning Caravaggio's working methods and

  10. An Exploratory Study: Assessment of Modeled Dioxin Exposure in Ceramic Art Studios (External Review Draft)

    EPA Science Inventory

    EPA has released an external review draft entitled, An Exploratory Study: Assessment of Modeled Dioxin Exposure in Ceramic Art Studios(External Review Draft). The public comment period and the external peer-review workshop are separate processes that provide opportunities ...

  11. Curiosity and Pedagogy: A Mixed-Methods Study of Student Experiences in the Design Studio

    ERIC Educational Resources Information Center

    Smith, Korydon H.

    2010-01-01

    Curiosity is often considered the foundation of learning. There is, however, little understanding of how (or if) pedagogy in higher education affects student curiosity, especially in the studio setting of architecture, interior design, and landscape architecture. This study used mixed-methods to investigate curiosity among design students in the…

  12. An Exploratory Study: Assessment of Modeled Dioxin Exposure in Ceramic Art Studios (Final Report, 2008)

    EPA Science Inventory

    EPA announced the availability of the final report, An Exploratory Study: Assessment of Modeled Dioxin Exposure in Ceramic Art Studios. This report investigates the potential dioxin exposure to artists/hobbyists who use ball clay to make pottery and related products. Derm...

  13. Architecture Studio Archive: A Case Study in the Comprehensive Digital Capture and Repository of Student Design Work as an Aid to Teaching, Research, and Accreditation

    ERIC Educational Resources Information Center

    Anderson, Ross; Arndell, Michael; Christensen, Sten

    2009-01-01

    The "Architecture Studio Archive" pilot sought to form a comprehensive digital archive of the diverse student work conducted in the first year of the Bachelor of Design in Architecture Degree at the University of Sydney. The design studio is the primary vehicle for teaching architectural design. It is a locus for creative activity, with…

  14. Instruments of Change: An Action Research Study of Studio Art Instruction in Teacher Education

    ERIC Educational Resources Information Center

    Soganci, Ismail O.

    2016-01-01

    This article narrates a nine-month action research project conducted in order to improve studio art instruction in a preservice art education programme in Turkey. Setting out to determine the relevant problems through interpretation of conversations, anecdotes, essays and observations of 16 third-year BA students, the instructional atmosphere was…

  15. Formal Learning Sequences and Progression in the Studio: A Framework for Digital Design Education

    ERIC Educational Resources Information Center

    Wärnestål, Pontus

    2016-01-01

    This paper examines how to leverage the design studio learning environment throughout long-term Digital Design education in order to support students to progress from tactical, well-defined, device-centric routine design, to confidently design sustainable solutions for strategic, complex, problems for a wide range of devices and platforms in the…

  16. ABA-insensitive3, ABA-insensitive5, and DELLAs Interact to activate the expression of SOMNUS and other high-temperature-inducible genes in imbibed seeds in Arabidopsis.

    PubMed

    Lim, Soohwan; Park, Jeongmoo; Lee, Nayoung; Jeong, Jinkil; Toh, Shigeo; Watanabe, Asuka; Kim, Junghyun; Kang, Hyojin; Kim, Dong Hwan; Kawakami, Naoto; Choi, Giltsu

    2013-12-01

    Seeds monitor the environment to germinate at the proper time, but different species respond differently to environmental conditions, particularly light and temperature. In Arabidopsis thaliana, light promotes germination but high temperature suppresses germination. We previously reported that light promotes germination by repressing SOMNUS (SOM). Here, we examined whether high temperature also regulates germination through SOM and found that high temperature activates SOM expression. Consistent with this, som mutants germinated more frequently than the wild type at high temperature. The induction of SOM mRNA at high temperature required abscisic acid (ABA) and gibberellic acid biosynthesis, and ABA-insensitive3 (ABI3), ABI5, and DELLAs positively regulated SOM expression. Chromatin immunoprecipitation assays indicated that ABI3, ABI5, and DELLAs all target the SOM promoter. At the protein level, ABI3, ABI5, and DELLAs all interact with each other, suggesting that they form a complex on the SOM promoter to activate SOM expression at high temperature. We found that high-temperature-inducible genes frequently have RY motifs and ABA-responsive elements in their promoters, some of which are targeted by ABI3, ABI5, and DELLAs in vivo. Taken together, our data indicate that ABI3, ABI5, and DELLAs mediate high-temperature signaling to activate the expression of SOM and other high-temperature-inducible genes, thereby inhibiting seed germination.

  17. Advanced Placement in Studio Art and Secondary Art Education Policy: Countering the Null Curriculum

    ERIC Educational Resources Information Center

    Graham, Mark A.; Sims-Gunzenhauser, Alice

    2009-01-01

    Because of education reform policy and misconceptions about artistry and artistic assessment, visual art education remains in the margins of high school education. One response to the lack of supportive arts education policy is the Advanced Placement (AP) Studio Art Program, a visual arts assessment at the high school level that engages large…

  18. The Book of the Sick of Santa Maria della Morte in Bologna and the Medical Organization of a Hospital in the Sixteenth-Century.

    PubMed

    Savoia, Paolo

    2016-01-01

    In 2012 a manuscript was rediscovered in the Biblioteca dell'Archiginnasio of Bologna, titled Libro degli infermi dell'Arciconfraternita di S. Maria della Morte. It is the record of incoming patients of one for the main hospitals of the city, devoted exclusively to the sick poor and not just to the poor, called Santa Maria della Morte, compiled by a young student assistant (astante) for the period 1558-1564. I publish here a transcription of a portion of this Libro pertaining to the year 1560. My introduction situates the manuscript within the context of the history of early modern Italian hospitals, describes the organization of the hospital of Santa Maria della Morte based on archival sources of the period, and finally highlights the connections between surgical and anatomical education and the internal organization of the hospital.

  19. The altarpieces of Della Robbia atelier in Marche region: investigations on technology and provenance

    NASA Astrophysics Data System (ADS)

    Amadori, M. L.; Barcelli, S.; Barcaioni, S.; Bouquillon, A.; Padeletti, G.; Pallante, P.

    2013-12-01

    Dissemination of Della Robbia glazed terracotta in the Marche (Italy) region started from the third decade of the 16th century. Numerous altarpieces, some of which no longer exist, document this artistic production. The protagonists of this diffusion phase were two of Andrea Della Robbia's sons, Marco (Fra Mattia) and Francesco (Fra Ambrogio). This paper shows the results of the scientific investigations carried out on constitutive materials of different altarpieces located in South Marche belonging to the Fra Mattia's production: the Coronation of Virgin between Saints Rocco, Sebastian, Peter martyr and Antonio abbot, dated back to 1527-1530, located in the collegiate church of S. Maria Assunta in Montecassiano; the Annunciation, dated back to 1520, placed in the church of S. Maria del Soccorso in Arcevia; the fragmentary Crowned Madonna and saints altarpiece, probably realized after 1531, today preserved in Civic Museum of Ripatransone. The first altarpiece was made in Montecassiano using two different assembling or production techniques: the external part of the lunette and the pillar strips are made of glazed polychrome terracotta, while the altar step and the internal part are an interesting and uncommon example of polychrome painted terracotta. The provenance of the glazed Arcevia altarpiece is not clear yet: some historians hypothesize a local manufacture of Fra Mattia and some others a Roman or Florentine production. The remaining parts of Ripatransone altarpiece are partially glazed and partially not coated perhaps because they were unfinished and not yet painted. Clay body samples collected from the above mentioned altarpieces were investigated using different analytical techniques (OM, XRD, XRF, PIXE) to point out differences in chemical and mineralogical composition and to determine if the altarpieces were made by using local raw clay materials or other clays from Tuscany or Campania as in the Della Robbia previous production. A comparison has also been

  20. [Population health surveillance of the general population living near Turin (Northern Italy) incinerator (SPoTT): methodology of the study].

    PubMed

    Bena, Antonella; Chiusolo, Monica; Orengia, Manuela; Cadum, Ennio; Farina, Elena; Musmeci, Loredana; Procopio, Enrico; Salamina, Giuseppe

    2016-01-01

    Si intende qui descrivere il sistema di sorveglianza sugli effetti sulla salute (SpoTT) dell'inquinamento ambientale nelle aree circostanti l'inceneritore di Torino. SPoTT ha 3 linee di attività: 1. monitoraggio epidemiologico degli effetti a breve termine attraverso analisi temporali e misura della correlazione tra livelli giornalieri di emissioni dell'impianto e andamento degli eventi individuati dagli archivi dei dimessi (SDO), di pronto soccorso e di mortalità; sono coinvolti coloro che nel 2013-2018 risiedevano nell'area di ricaduta delle emissioni; 2. sorveglianza epidemiologica degli effetti a lungo termine, stimando tassi standardizzati di mortalità e morbosità; a ogni soggetto è attribuito il valore stimato di esposizione cumulato nel tempo caratteristico della residenza anagrafica; le informazioni sulla salute sono reperite dagli archivi SDO, di mortalità e dai certificati di assistenza al parto; sono studiati due decenni pre-post l'avvio dell'impianto: 2003-2012 e 2013-2022; 3. monitoraggio biologico con misurazione pre-post di metalli, PCDD/F, PCB, OH-IPA; sono coinvolti 196 residenti esposti e 196 di controllo di 35-69 anni, campionati a caso dalle anagrafi comunali; sono effettuate misure di funzionalità endocrina e respiratoria, pressione arteriosa, rischio cardiovascolare; l'esposizione cumulativa sarà stimata per ciascuna persona campionata integrando l'indirizzo di residenza, il tempo di permanenza in ciascun indirizzo e i dati ricavati dai modelli di ricaduta; sarà costituita una biobanca per future indagini di laboratorio; sono coinvolti anche 20 allevatori e i lavoratori dell'impianto. Una quarta linea di attività, non descritta in questo articolo, riguarda il monitoraggio della salute dei lavoratori addetti all'impianto. SPoTT è il primo studio in Italia su inceneritori e salute che adotta un disegno di studio longitudinale di adeguata potenza sia per i residenti sia per i lavoratori. I primi risultati sono attesi nel corso del 2016.

  1. Robotic Design Studio: Exploring the Big Ideas of Engineering in a Liberal Arts Environment.

    ERIC Educational Resources Information Center

    Turbak, Franklyn; Berg, Robbie

    2002-01-01

    Suggests that it is important to introduce liberal arts students to the essence of engineering. Describes Robotic Design Studio, a course in which students learn how to design, assemble, and program robots made out of LEGO parts, sensors, motors, and small embedded computers. Represents an alternative vision of how robot design can be used to…

  2. Using Cascading Style Sheets to Design a Fly-Out Menu with Microsoft Visual Studio

    ERIC Educational Resources Information Center

    Liu, Chang; Downing, Charles

    2010-01-01

    The menu has become an integrated component within nearly all professionally designed websites. This teaching tip presents a no-code way to design either a vertical or a horizontal fly-out menu by using Cascading Style Sheets (CSS) within Microsoft Visual Studio 2008. The approach described in this tip helps students fully understand how to…

  3. Calorimetria nucleare in collisioni tra ioni pesanti ad energie intermedie

    NASA Astrophysics Data System (ADS)

    Spezzi, L.

    2002-07-01

    Nel presente lavoro di tesi ci si e' occupati di uno studio sistematico di misure di temperatura ed energia di eccitazione in sistemi nucleari formati in reazioni tra ioni pesanti ad energie intermedie. La temperatura a stata misurata tramite due diversi metodi: rapporto tra le rese di isotopi che differiscono di uno stesso numero di nucleoni ( d/t-3He/4He , 3He/4He -6Li/7Li) - temperatura isotopica -, e rapporto tra le popolazioni degli stati eccitati in frammenti instabili (5Li e 6Li) che decadono in particelle leggere in coincidenza - temperatura di emissione. Le misure in esame sono state effettuate presso i Laboratori Nazionali del Sud per i sistemi 93Nb+93Nb, 93Nb+116,124Sn, 116,120Sn+116,124Sn e 116Sn+93Nb ad energie comprese tra 17 e 40 A MeV. L'apparato di rivelazione era costituito da un odoscopio ad alta granularite (96 telescopi Si (50micron)-Si(300micron)-CsI(Tl) ) e basse soglie di rivelazione, utilizzato sia per identificare risonanze in frammenti eccitati che per misure di rese di isotopi di frammenti con 2<=Z<=6, e dal multirivelatore FIASCO che, grazie alla misura contemporanea di posizione e tempo di volo dei frammenti provenienti dal proiettile (PLF - Projectile Like Fragments) e dal bersaglio (TLF - Target Like Fragment), e' stato utilizzato per misurare direttamente l'energia di eccitazione del sistema in studio. Analisi precedenti, condotte nell'ambito di varie collaborazioni, hanno messo in evidenza la possible esistenza di una transizione di fase liquido-gas del primo ordine nella materia nucleare. In tale contesto, ci siamo occupati di una verifica della curva calorica nucleare, ovvero della correlazione esistente fra temperatura ed energia di eccitazione del sistema, indagando, nel contempo, sulla sua dipendenza dalla massa del sistema che si frammenta. Si e' effettuato, inoltre, un confronto fra i due diversi metodi di misura della temperatura (temperatura isotopica e di emissione): l'andamento plateau-like della curva calorica e' stato

  4. ABA-INSENSITIVE3, ABA-INSENSITIVE5, and DELLAs Interact to Activate the Expression of SOMNUS and Other High-Temperature-Inducible Genes in Imbibed Seeds in Arabidopsis[W

    PubMed Central

    Lim, Soohwan; Park, Jeongmoo; Lee, Nayoung; Jeong, Jinkil; Toh, Shigeo; Watanabe, Asuka; Kim, Junghyun; Kang, Hyojin; Kim, Dong Hwan; Kawakami, Naoto; Choi, Giltsu

    2013-01-01

    Seeds monitor the environment to germinate at the proper time, but different species respond differently to environmental conditions, particularly light and temperature. In Arabidopsis thaliana, light promotes germination but high temperature suppresses germination. We previously reported that light promotes germination by repressing SOMNUS (SOM). Here, we examined whether high temperature also regulates germination through SOM and found that high temperature activates SOM expression. Consistent with this, som mutants germinated more frequently than the wild type at high temperature. The induction of SOM mRNA at high temperature required abscisic acid (ABA) and gibberellic acid biosynthesis, and ABA-INSENSITIVE3 (ABI3), ABI5, and DELLAs positively regulated SOM expression. Chromatin immunoprecipitation assays indicated that ABI3, ABI5, and DELLAs all target the SOM promoter. At the protein level, ABI3, ABI5, and DELLAs all interact with each other, suggesting that they form a complex on the SOM promoter to activate SOM expression at high temperature. We found that high-temperature-inducible genes frequently have RY motifs and ABA-responsive elements in their promoters, some of which are targeted by ABI3, ABI5, and DELLAs in vivo. Taken together, our data indicate that ABI3, ABI5, and DELLAs mediate high-temperature signaling to activate the expression of SOM and other high-temperature-inducible genes, thereby inhibiting seed germination. PMID:24326588

  5. Igniting GameZombie TV: A Longitudinal Autoethnography of a Student-Fueled Game Media Studio

    ERIC Educational Resources Information Center

    Striker, Spencer

    2012-01-01

    "Igniting GameZombie TV" utilizes an accessible, energetic, postmodern style to recall how Spencer Striker founded GameZombie TV at Indiana University in the fall of 2006, built the project into an award-winning game media studio, and then expanded the initiative to the University of Wisconsin in the fall of 2009. Through grit and a…

  6. Exploring the Physics of Music with Temperament Studio

    NASA Astrophysics Data System (ADS)

    Durfee, Dallin; Colton, John

    2016-03-01

    The physics of waves, resonance, harmonics, and beats has determined how musical instruments are tuned, and has even affected the kinds of music written in different time periods. The laws of physics make it impossible for any fixed scale to have perfect consonance for all chords in all keys, and as a result, various musical scales, or temperaments, have been developed and used throughout history. The study of musical temperament is a rich application of wave physics. It ties several principles together in a context which can be very motivating for students. Furthermore, the topic is accessible to students in introductory classes. We have developed an open source application called Temperament Studio which allows students to explore musical temperament and to hear and measure the effects predicted by wave physics.

  7. The Role of Healthy Social Interaction and Communications in Provoking Creativity in the Design Studio

    ERIC Educational Resources Information Center

    Sidawi, Bhzad

    2016-01-01

    Design is a social phenomenon and researchers suggest that negotiations and communications between designers are essential to initiate creativity. Within the design studio environment, a number of factors affect the healthy social interaction and design negotiations, such as the teaching style of tutors and the culture that governs a design studio…

  8. The Prefabricated Interior Design Studio: An Exploration into the History and Sustainability of Interior Prefabrication

    ERIC Educational Resources Information Center

    Schneiderman, Deborah; Freihoefer, Kara

    2013-01-01

    This article examines the integration of prefabrication into an interior design studio. A review of the literature revealed that while there is a paucity of categorical research focused on this subject, the subject is historically significant with an abundance of evidence regarding the prefabrication of the interior environment dating back…

  9. Using a Studio-Based Pedagogy to Engage Students in the Design of Mobile-Based Media

    ERIC Educational Resources Information Center

    Mathews, James M.

    2010-01-01

    The article presents a brief overview of the Neighbourhood Game Design Project, a studio-based curriculum intervention aimed at engaging students in the design of place-based mobile games and interactive stories using geo-locative technologies (for example, GPS enabled cell phones). It describes the three curricular components that defined the…

  10. La meridiana di Egnazio Danti nella Torre dei Venti in Vaticano: un'icona della riforma Gregoriana del calendario

    NASA Astrophysics Data System (ADS)

    Sigismondi, Costantino

    2014-05-01

    La Torre dei Venti domina l’angolo Sud Ovest del cortile della Pigna (nell'area dei Musei Vaticani), ed è inclusa negli ambienti dell'Archivio Segreto Vaticano. Non è aperta al pubblico, ma è universalmente nota per la fama che da oltre quattrocento anni la circonda, legata alle vicende della riforma Gregoriana del calendario. La meridiana tracciata da padre Egnazio Danti (1536-1586) nella torre dei Venti, fu visitata anche da Gregorio XIII, probabilmente il 21 marzo 1581 come suppone il padre Stein, per convincersi dell'anticipo ormai arrivato a dieci giorni dell'equinozio di primavera sulla data che il concilio di Nicea aveva fissato al 21 marzo per il computo pasquale. La ricognizione astrometrica del febbraio-marzo 2009 fatta dall'autore viene qui presentata.

  11. [Adalberto Pazzini and the origins of the Istituto di Storia della Medicina].

    PubMed

    Conforti, Maria

    2006-01-01

    The first part of the paper deals with the Italian tradition of medical history in the 1930s, when Adalberto Pazzini became the most successful medical historian in Italy. Its second part deals with the founding and renovation (1938 and 1954 respectively) of the Istituto di Storia della Medicina at Rome University, with a description of the innovative--and largely utopian--planning of the Library and of the Museum and didactic collections by Pazzini.

  12. Gibberellin DELLA signaling targets the retromer complex to redirect protein trafficking to the plasma membrane

    PubMed Central

    Salanenka, Yuliya; Verstraeten, Inge; Löfke, Christian; Tabata, Kaori; Naramoto, Satoshi; Glanc, Matouš; Friml, Jiří

    2018-01-01

    The plant hormone gibberellic acid (GA) is a crucial regulator of growth and development. The main paradigm of GA signaling puts forward transcriptional regulation via the degradation of DELLA transcriptional repressors. GA has also been shown to regulate tropic responses by modulation of the plasma membrane incidence of PIN auxin transporters by an unclear mechanism. Here we uncovered the cellular and molecular mechanisms by which GA redirects protein trafficking and thus regulates cell surface functionality. Photoconvertible reporters revealed that GA balances the protein traffic between the vacuole degradation route and recycling back to the cell surface. Low GA levels promote vacuolar delivery and degradation of multiple cargos, including PIN proteins, whereas high GA levels promote their recycling to the plasma membrane. This GA effect requires components of the retromer complex, such as Sorting Nexin 1 (SNX1) and its interacting, microtubule (MT)-associated protein, the Cytoplasmic Linker-Associated Protein (CLASP1). Accordingly, GA regulates the subcellular distribution of SNX1 and CLASP1, and the intact MT cytoskeleton is essential for the GA effect on trafficking. This GA cellular action occurs through DELLA proteins that regulate the MT and retromer presumably via their interaction partners Prefoldins (PFDs). Our study identified a branching of the GA signaling pathway at the level of DELLA proteins, which, in parallel to regulating transcription, also target by a nontranscriptional mechanism the retromer complex acting at the intersection of the degradation and recycling trafficking routes. By this mechanism, GA can redirect receptors and transporters to the cell surface, thus coregulating multiple processes, including PIN-dependent auxin fluxes during tropic responses. PMID:29463731

  13. 76 FR 5832 - International Business Machines (IBM), Software Group Business Unit, Optim Data Studio Tools QA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-02

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,554] International Business Machines (IBM), Software Group Business Unit, Optim Data Studio Tools QA, San Jose, CA; Notice of... determination of the TAA petition filed on behalf of workers at International Business Machines (IBM), Software...

  14. Mass Spec Studio for Integrative Structural Biology

    PubMed Central

    Rey, Martial; Sarpe, Vladimir; Burns, Kyle; Buse, Joshua; Baker, Charles A.H.; van Dijk, Marc; Wordeman, Linda; Bonvin, Alexandre M.J.J.; Schriemer, David C.

    2015-01-01

    SUMMARY The integration of biophysical data from multiple sources is critical for developing accurate structural models of large multiprotein systems and their regulators. Mass spectrometry (MS) can be used to measure the insertion location for a wide range of topographically sensitive chemical probes, and such insertion data provide a rich, but disparate set of modeling restraints. We have developed a software platform that integrates the analysis of label-based MS data with protein modeling activities (Mass Spec Studio). Analysis packages can mine any labeling data from any mass spectrometer in a proteomics-grade manner, and link labeling methods with data-directed protein interaction modeling using HADDOCK. Support is provided for hydrogen/ deuterium exchange (HX) and covalent labeling chemistries, including novel acquisition strategies such as targeted HX-tandem MS (MS2) and data-independent HX-MS2. The latter permits the modeling of highly complex systems, which we demonstrate by the analysis of microtubule interactions. PMID:25242457

  15. Does the Medium Matter in Collaboration? Using Visually Supported Collaboration Technology in an Interior Design Studio

    ERIC Educational Resources Information Center

    Cho, Ji Young; Cho, Moon-Heum; Kozinets, Nadya

    2016-01-01

    With the recognition of the importance of collaboration in a design studio and the advancement of technology, increasing numbers of design students collaborate with others in a technology-mediated learning environment (TMLE); however, not all students have positive experiences in TMLEs. One possible reason for unsatisfactory collaboration…

  16. Development of the updated system of city underground pipelines based on Visual Studio

    NASA Astrophysics Data System (ADS)

    Zhang, Jianxiong; Zhu, Yun; Li, Xiangdong

    2009-10-01

    Our city has owned the integrated pipeline network management system with ArcGIS Engine 9.1 as the bottom development platform and with Oracle9i as basic database for storaging data. In this system, ArcGIS SDE9.1 is applied as the spatial data engine, and the system was a synthetic management software developed with Visual Studio visualization procedures development tools. As the pipeline update function of the system has the phenomenon of slower update and even sometimes the data lost, to ensure the underground pipeline data can real-time be updated conveniently and frequently, and the actuality and integrity of the underground pipeline data, we have increased a new update module in the system developed and researched by ourselves. The module has the powerful data update function, and can realize the function of inputting and outputting and rapid update volume of data. The new developed module adopts Visual Studio visualization procedures development tools, and uses access as the basic database to storage data. We can edit the graphics in AutoCAD software, and realize the database update using link between the graphics and the system. Practice shows that the update module has good compatibility with the original system, reliable and high update efficient of the database.

  17. Aspetti deontologici e giuridici della Responsabilità professionale del chirurgo in Italia. Evoluzione storica a partire dal '900.

    PubMed

    Picardi, Nicola

    2018-01-01

    È pleonastico ricordare che ogni individuo raziocinante delle essere responsabile delle sue azioni: deve agire con la coscienza degli scopi che si propone evitando possibili conseguenze negative dei suoi atti. In ambito medico questo tipo di responsabilità è codificata con le norme della "deontologia". Per secoli l'arte terapeutica è stata praticata da individui dotati di una particolare vocazione ed una particolare cultura acquisita da Maestri dell'arte ancor prima che dalla propria esperienza, con nozioni di erboristeria e di elementari conoscenze anatomiche e di fisiologia, circondati da un'aura sacerdotale e da un rispetto derivante dal timore e dall'ammirazione per il coraggio e auspicabilmente dai successi, e facendo riferimento nell'occidente mediterraneo alle regole operative fissate nel Giuramento di Ippocrate, di significato tra il sacro ed il deontologico. Lo sviluppo delle tecniche anestesiologiche a partire dalla seconda metà dell'800 ha determinato l'ampliamento delle iniziative chirurgiche di tipo elettivo, a fianco con gli storici interventi in emergenza per la cura di lesioni traumatiche, ancor prima delle acquisizioni riguardanti le infezioni. Con l'espansione del campo di azione della chirurgia, le possibili complicanze ed i possibili insuccessi hanno fatto da contrappeso ai sentimenti di rispetto e di fiducia nei confronti dei chirurghi, giungendo a far assimilare in tali casi la loro opera quale causa all'origine di danni, provocati rientrando quindi nella categoria dei reati sottoposti alla Legge penale. Così, al termine deontologico di "responsabilità" valido per ogni iniziativa ed ogni professione, per i medici è venuto ad associarsi la qualifica di "professionale", con un significato di presunta colpevolezza. Da una parte le regole deontologiche si sono ampliate, ed hanno coinvolto direttamente il paziente nella fase decisionale delle terapie chirurgiche, formalizzate programmaticamente in moderni codici deontologici ed

  18. Studio Design Work in First Year Architectural Education. Advisory Centre Occasional Papers in University Education.

    ERIC Educational Resources Information Center

    Claridge, Philip George Brian

    A course for first-year architectural students is described. The approach concentrated on developing an understanding of the nature of design activity through exploration of the kind of thinking that may be applied in order to improve the first-year studio work. The course is based on the following premises: (1) it is possible and educationally…

  19. The In-Depth Studio Approach: Incorporating an Art Museum Program into a Pre-Primary Classroom

    ERIC Educational Resources Information Center

    Trimis, Eli; Savva, Andri

    2004-01-01

    Trimis and Savva detail the in-depth studio approach, which enables students to explore materials and techniques in-depth and to progress in developmental stages, as part of a larger study of museum education in Cyprus. Their aim was to introduce preservice teachers to ways of implementing programs that link museum education with art activities in…

  20. Balancing Expression and Structure in Game Design: Developing Computational Participation Using Studio-Based Design Pedagogy

    ERIC Educational Resources Information Center

    DeVane, Ben; Steward, Cody; Tran, Kelly M.

    2016-01-01

    This article reports on a project that used a game-creation tool to introduce middle-school students ages 10 to 13 to problem-solving strategies similar to those in computer science through the lens of studio-based design arts. Drawing on historic paradigms in design pedagogy and contemporary educational approaches in the digital arts to teach…

  1. Drawing with Light and Clay: Teaching and Learning in the Art Studio as Pathways to Engagement

    ERIC Educational Resources Information Center

    Albertson, Constant; Davidson, Miriam

    2007-01-01

    In this essay, Albertson and Davidson explore the attributes of photography and ceramic arts education to identify eight key elements integral to engagement in these art studios for under-served and disenchanted learners. They suggest that these key elements can provide numerous clues as to how teachers and school communities might reimagine both…

  2. Reconstruction of full glacial environments and summer temperatures from Lago della Costa, a refugial site in Northern Italy

    NASA Astrophysics Data System (ADS)

    Samartin, Stéphanie; Heiri, Oliver; Kaltenrieder, Petra; Kühl, Norbert; Tinner, Willy

    2016-07-01

    Vegetation and climate during the last ice age and the Last Glacial Maximum (LGM, ∼23,000-19,000 cal BP) were considerably different than during the current interglacial (Holocene). Cold climatic conditions and growing ice-sheets during the last glaciation radically reduced forest extent in Europe to a restricted number of so-called ;refugia;, mostly located in the southern part of the continent. On the basis of paleobotanical analyses the Euganian Hills (Colli Euganei) in northeastern Italy have previously been proposed as one of the northernmost refugia of temperate trees (e.g. deciduous Quercus, Tilia, Ulmus, Fraxinus excelsior, Acer, Abies alba, Fagus sylvatica, Carpinus and Castanea) in Europe. In this study we provide the first quantitative, vegetation independent summer air temperature reconstruction for Northern Italy spanning the time ∼31,000-17,000 cal yr BP, which covers the coldest periods of the last glacial, including the LGM and Heinrich stadials 1 to 3. Chironomids preserved in a lake sediment core from Lago della Costa (7m a.s.l.), a small lake at the south-eastern edge of the Euganean Hills, allowed quantitative reconstruction of Full and Late Glacial summer air temperatures using a combined Swiss-Norwegian temperature inference model based on chironomid assemblages from 274 lakes. Chironomid and pollen evidence from Lago della Costa derives from finely stratified autochthonous organic gyttja sediments, which excludes major sediment mixing or reworking. After reconstructing paleo-temperatures, we address the question whether climate conditions were warm enough to permit the local survival of temperate tree species during the LGM and whether local expansions and pollen-inferred contractions of temperate tree taxa coincided with chironomid-inferred climatic changes. Our results suggest that chironomids at Lago della Costa have responded to major climatic fluctuations such as temperature decreases during the LGM and Heinrich stadials. The

  3. Exploring the Learning Problems and Resource Usage of Undergraduate Industrial Design Students in Design Studio Courses

    ERIC Educational Resources Information Center

    Chen, Wenzhi

    2016-01-01

    Design is a powerful weapon for modern companies so it is important to have excellent designers in the industry. The purpose of this study is to explore the learning problems and the resources that students use to overcome problems in undergraduate industrial design studio courses. A survey with open-type questions was conducted to collect data.…

  4. Digital Technology in the Tertiary Dance Technique Studio: Expanding Student Engagement through Collaborative and Co-Creative Experiences

    ERIC Educational Resources Information Center

    Huddy, Avril

    2017-01-01

    Digital technology has long been integrated into the mainstream learning environment in a variety of ways from basic teaching delivery tools to specific courseware; however, it has struggled to make an impact in the dance technique studio. Despite the enthusiastic and alacritous integration of digital technologies within the repertoire and…

  5. Using Online Studio Groups to Improve Writing Competency: A Pilot Study in a Quality Improvement Methods Course

    ERIC Educational Resources Information Center

    Kovach, Jamison V.; Miley, Michelle; Ramos, Miguel A.

    2012-01-01

    Communication skills are a significant contributor to an individual's success in the workplace. Unfortunately, students often have trouble expressing their ideas in written form and the poor quality of students' written work often impedes the learning process. This pilot study investigates the use of online writing studios within a quality…

  6. Welcoming Linguistic Diversity and Saying Adios to Remediation: Stretch and Studio Composition at a Hispanic-Serving Institution

    ERIC Educational Resources Information Center

    Davila, Bethany A.; Elder, Cristyn L.

    2017-01-01

    In this program profile, we describe the stretch/studio program recently implemented at the University of New Mexico. This program responds both to an institutional move away from remediation and to the large number of linguistically and racially diverse students at our institution. In this profile, we describe the new program's curriculum, which…

  7. High Sensitivity Crosslink Detection Coupled With Integrative Structure Modeling in the Mass Spec Studio *

    PubMed Central

    Sarpe, Vladimir; Rafiei, Atefeh; Hepburn, Morgan; Ostan, Nicholas; Schryvers, Anthony B.; Schriemer, David C.

    2016-01-01

    The Mass Spec Studio package was designed to support the extraction of hydrogen-deuterium exchange and covalent labeling data for a range of mass spectrometry (MS)-based workflows, to integrate with restraint-driven protein modeling activities. In this report, we present an extension of the underlying Studio framework and provide a plug-in for crosslink (XL) detection. To accommodate flexibility in XL methods and applications, while maintaining efficient data processing, the plug-in employs a peptide library reduction strategy via a presearch of the tandem-MS data. We demonstrate that prescoring linear unmodified peptide tags using a probabilistic approach substantially reduces search space by requiring both crosslinked peptides to generate sparse data attributable to their linear forms. The method demonstrates highly sensitive crosslink peptide identification with a low false positive rate. Integration with a Haddock plug-in provides a resource that can combine multiple sources of data for protein modeling activities. We generated a structural model of porcine transferrin bound to TbpB, a membrane-bound receptor essential for iron acquisition in Actinobacillus pleuropneumoniae. Using mutational data and crosslinking restraints, we confirm the mechanism by which TbpB recognizes the iron-loaded form of transferrin, and note the requirement for disparate sources of restraint data for accurate model construction. The software plugin is freely available at www.msstudio.ca. PMID:27412762

  8. High Sensitivity Crosslink Detection Coupled With Integrative Structure Modeling in the Mass Spec Studio.

    PubMed

    Sarpe, Vladimir; Rafiei, Atefeh; Hepburn, Morgan; Ostan, Nicholas; Schryvers, Anthony B; Schriemer, David C

    2016-09-01

    The Mass Spec Studio package was designed to support the extraction of hydrogen-deuterium exchange and covalent labeling data for a range of mass spectrometry (MS)-based workflows, to integrate with restraint-driven protein modeling activities. In this report, we present an extension of the underlying Studio framework and provide a plug-in for crosslink (XL) detection. To accommodate flexibility in XL methods and applications, while maintaining efficient data processing, the plug-in employs a peptide library reduction strategy via a presearch of the tandem-MS data. We demonstrate that prescoring linear unmodified peptide tags using a probabilistic approach substantially reduces search space by requiring both crosslinked peptides to generate sparse data attributable to their linear forms. The method demonstrates highly sensitive crosslink peptide identification with a low false positive rate. Integration with a Haddock plug-in provides a resource that can combine multiple sources of data for protein modeling activities. We generated a structural model of porcine transferrin bound to TbpB, a membrane-bound receptor essential for iron acquisition in Actinobacillus pleuropneumoniae Using mutational data and crosslinking restraints, we confirm the mechanism by which TbpB recognizes the iron-loaded form of transferrin, and note the requirement for disparate sources of restraint data for accurate model construction. The software plugin is freely available at www.msstudio.ca. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  9. Modeling lift operations with SASmacr Simulation Studio

    NASA Astrophysics Data System (ADS)

    Kar, Leow Soo

    2016-10-01

    Lifts or elevators are an essential part of multistorey buildings which provide vertical transportation for its occupants. In large and high-rise apartment buildings, its occupants are permanent, while in buildings, like hospitals or office blocks, the occupants are temporary or users of the buildings. They come in to work or to visit, and thus, the population of such buildings are much higher than those in residential apartments. It is common these days that large office blocks or hospitals have at least 8 to 10 lifts serving its population. In order to optimize the level of service performance, different transportation schemes are devised to control the lift operations. For example, one lift may be assigned to solely service the even floors and another solely for the odd floors, etc. In this paper, a basic lift system is modelled using SAS Simulation Studio to study the effect of factors such as the number of floors, capacity of the lift car, arrival rate and exit rate of passengers at each floor, peak and off peak periods on the system performance. The simulation is applied to a real lift operation in Sunway College's North Building to validate the model.

  10. Studio optics: Adapting interactive engagement pedagogy to upper-division physics

    NASA Astrophysics Data System (ADS)

    Sorensen, Christopher M.; McBride, Dyan L.; Rebello, N. Sanjay

    2011-03-01

    The use of interactive engagement strategies to improve learning in introductory physics is not new, but have not been used as often for upper-division physics courses. We describe the development and implementation of a Studio Optics course for upper-division physics majors at Kansas State University. The course adapts a three-stage Karplus learning cycle and other elements to foster an environment that promotes learning through an integration of lecture, laboratories, and problem solving. Some of the instructional materials are described. We discuss the evaluation of the course using data collected from student interviews, a conceptual survey, an attitudinal survey, and the instructor's reflections. Overall, students responded positively to the new format and showed modest gains in learning. The instructor's experiences compared favorably with the traditional course that he had taught in the past.

  11. Writing-Intensive Approaches in a Typographic Design Studio Class: Using Writing as a Tool toward More Intentional Design

    ERIC Educational Resources Information Center

    Fowler, Michael

    2015-01-01

    Taking advantage of a university-wide initiative that requires all students during their course of study to take at least one of their writing intensive classes in their major, the author relates how he was spurred to formulate one of his graphic design studio classes to accommodate the writing-intensive requirement. He had been intuitively…

  12. The sound insulations of studio doors. Part 1: Door blanks

    NASA Astrophysics Data System (ADS)

    Plumb, G. D.; Clark, R.

    The sound insulations of a range of different door blanks were measured. The results were compared with the sound insulations of existing BBC door blanks. The new doors were made from medium density fiberboard (MDF) which is more stable than the blockboard used in existing studio doors. Consequently, they should require less maintenance and adjustment and should have a longer lifespan. The doors had higher sound insulations for their weight than existing designs, which might permit savings in the costs of the surrounding building structures. Overall construction costs of the door blanks themselves are likely to be similar to those of existing designs. A companion Report (BBC RD 1994/15) describes sound insulation measurements made on plant-on door seals. The intention of this work was to simplify the construction of the door frame and the fitting of the seals to reduce costs.

  13. Collaboration through Flickr & Skype: Can Web 2.0 Technology Substitute the Traditional Design Studio in Higher Design Education?

    ERIC Educational Resources Information Center

    Fleischmann, Katja

    2014-01-01

    Technology has not only changed the work practice of designers but also how design is taught and learned. The emergence of digital technology has made computer labs a central learning space for design students. Since this change, studio-based learning in its traditional sense appears to be in decline in higher education institutions. This is in…

  14. A Rediscovered Alliance: Can New Music Performance Teaching Policy Save Music Education? A New Framework for the Music Studio

    ERIC Educational Resources Information Center

    Wexler, Mathias

    2012-01-01

    Music education in K-12 school programs may continue to lose ground to other subjects unless music education and performance studies are viewed as interdependent. The author argues that the reinvigoration of both music education and performance requires that the studio experience integrate a research-based pedagogy, multi-stylistic range of…

  15. THREaD Mapper Studio: a novel, visual web server for the estimation of genetic linkage maps

    PubMed Central

    Cheema, Jitender; Ellis, T. H. Noel; Dicks, Jo

    2010-01-01

    The estimation of genetic linkage maps is a key component in plant and animal research, providing both an indication of the genetic structure of an organism and a mechanism for identifying candidate genes associated with traits of interest. Because of this importance, several computational solutions to genetic map estimation exist, mostly implemented as stand-alone software packages. However, the estimation process is often largely hidden from the user. Consequently, problems such as a program crashing may occur that leave a user baffled. THREaD Mapper Studio (http://cbr.jic.ac.uk/threadmapper) is a new web site that implements a novel, visual and interactive method for the estimation of genetic linkage maps from DNA markers. The rationale behind the web site is to make the estimation process as transparent and robust as possible, while also allowing users to use their expert knowledge during analysis. Indeed, the 3D visual nature of the tool allows users to spot features in a data set, such as outlying markers and potential structural rearrangements that could cause problems with the estimation procedure and to account for them in their analysis. Furthermore, THREaD Mapper Studio facilitates the visual comparison of genetic map solutions from third party software, aiding users in developing robust solutions for their data sets. PMID:20494977

  16. Design and Simulation of a Birdcage Coil using CST Studio Suite for Application at 7T

    NASA Astrophysics Data System (ADS)

    Palau Tomas, Bernat; Li, Houmin; Anjum, M. R.

    2013-12-01

    This work describes the study of coils for Magnetic Resonance Imaging (MRI) applications. The principal objective is the design of a birdcage Radio Frequency (RF) coil to use in a 7 Tesla (7T) scanner. Higher strength field generates a better SNR and increased chemical shift effect, improving spectral fat suppression and spectroscopy. Moreover, a better SNR increases the spatial resolution or reduces the imaging time. This research work presented recent developments based on high field 7T design using CST studio. The birdcage coil achieves circular polarization and generates a high homogeneous radio frequency magnetic field under many conditions. Design of a Birdcage coil for a 7T to obtain the images from s mall animals (i.e. mouse). It opens the door to design and construct a Birdcage coil for a 7T to obtain human brain images. Firstly we design a birdcage coil then the results are obtained with simulator CST Wave Studio, creating a 3D model and generating a simulation. Finally the parameters are re adjusted to obtain our desired Larmor frequency 298.2 MHz for a correct operation in 7T. This research work demonstrates the theoretical results from our design and shows the designed antenna behavior.

  17. Three-Dimensional Simulation of Traveling-Wave Tube Cold-Test Characteristics Using CST MICROWAVE STUDIO

    NASA Technical Reports Server (NTRS)

    Chevalier, Christine T.; Herrmann, Kimberly A.; Kory, Carol L.; Wilson, Jeffrey D.; Cross, Andrew W.; Santana , Samuel

    2003-01-01

    The electromagnetic field simulation software package CST MICROWAVE STUDIO (MWS) was used to compute the cold-test parameters - frequency-phase dispersion, on-axis impedance, and attenuation - for a traveling-wave tube (TWT) slow-wave circuit. The results were compared to experimental data, as well as to results from MAFIA, another three-dimensional simulation code from CST currently used at the NASA Glenn Research Center (GRC). The strong agreement between cold-test parameters simulated with MWS and those measured experimentally demonstrates the potential of this code to reduce the time and cost of TWT development.

  18. HPLC studio: a novel software utility to perform HPLC chromatogram comparison for screening purposes.

    PubMed

    García, J B; Tormo, José R

    2003-06-01

    A new tool, HPLC Studio, was developed for the comparison of high-performance liquid chromatography (HPLC) chromatograms from microbial extracts. The new utility makes it possible to create a virtual chromatogram by mixing up to 20 individual chromatograms. The virtual chromatogram is the first step in establishing a ranking of the microbial fermentation conditions based on either the area or diversity of HPLC peaks. The utility was used to maximize the diversity of secondary metabolites tested from a microorganism and therefore increase the chances of finding new lead compounds in a drug discovery program.

  19. Dominant and Pleiotropic Effects of a GAI Gene in Wheat Results from a Lack of Interaction between DELLA and GID11[C][W][OA

    PubMed Central

    Wu, Jing; Kong, Xiuying; Wan, Jianmin; Liu, Xueying; Zhang, Xin; Guo, Xiuping; Zhou, Ronghua; Zhao, Guangyao; Jing, Ruilian; Fu, Xiangdong; Jia, Jizeng

    2011-01-01

    Dominance, semidominance, and recessiveness are important modes of Mendelian inheritance. The phytohormone gibberellin (GA) regulates many plant growth and developmental processes. The previously cloned semidominant GA-insensitive (GAI) genes Reduced height1 (Rht1) and Rht2 in wheat (Triticum aestivum) were the basis of the Green Revolution. However, no completely dominant GAI gene has been cloned. Here, we report the molecular characterization of Rht-B1c, a dominant GAI allele in wheat that confers more extreme characteristics than its incompletely dominant alleles. Rht-B1c is caused by a terminal repeat retrotransposons in miniature insertion in the DELLA domain. Yeast two-hybrid assays showed that Rht-B1c protein fails to interact with GA-INSENSITIVE DWARF1 (GID1), thereby blocking GA responses and resulting in extreme dwarfism and pleiotropic effects. By contrast, Rht-B1b protein only reduces interaction with GID1. Furthermore, we analyzed its functions using near-isogenic lines and examined its molecular mechanisms in transgenic rice. These results indicated that the affinity between GID1 and DELLA proteins is key to regulation of the stability of DELLA proteins, and differential interactions determine dominant and semidominant gene responses to GA. PMID:22010107

  20. SBL-Online: Implementing Studio-Based Learning Techniques in an Online Introductory Programming Course to Address Common Programming Errors and Misconceptions

    ERIC Educational Resources Information Center

    Polo, Blanca J.

    2013-01-01

    Much research has been done in regards to student programming errors, online education and studio-based learning (SBL) in computer science education. This study furthers this area by bringing together this knowledge and applying it to proactively help students overcome impasses caused by common student programming errors. This project proposes a…

  1. Lights, Camera, Action ... and Cooling - The case for centralized low carbon energy at Fox Studios

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Robinson, Alastair; Regnier, Cindy

    Fox Studios partnered with the U.S. Department of Energy (DOE) to develop and implement solutions to retrofit two production stages and one of its central cooling plants, to reduce energy consumption by at least 30% as part of DOE’s Commercial Building Partnerships (CBP) Program. Although this case study reports expected savings arising from proposed design recommendations for a unique building type and the unusual load characteristics associated with its use, the EEMs implemented for the central plant are applicable to any large campus, office and higher education facility. The intent is that by making the energy-efficiency measures (EEMs) set thatmore » were assessed as cost-effective from this project applicable to a larger number of buildings on the campus Fox Studios will be able to implement an integrated campus-wide energy strategy for the long term. The significant challenges for this project in the design phase included identifying how to assess and analyze multiple system types, develop a coherent strategy for assessment and analysis, implement the measurement and verification activities to collect the appropriate data (in terms of capturing ‘normal’ operating characteristics and granularity) and determine the best approach to providing cooling to the site buildings based on the nature of existing systems and the expected improvement in energy performance of the central cooling plant. The analytical framework adopted provides a blueprint for similar projects at other large commercial building campuses.« less

  2. Reducing Medical Students' Stigmatization of People with Chronic Mental Illness: A Field Intervention at the "Living Museum" State Hospital Art Studio

    ERIC Educational Resources Information Center

    Cutler, Janis L.; Harding, Kelli J.; Hutner, Lucy A.; Cortland, Clarissa; Graham, Mark J.

    2012-01-01

    Objective: The authors designed an intervention to reduce beginning medical students' stigmatization of people with chronic mental illness (CMI). Methods: Pre-clinical medical students visited a state psychiatric facility's "Living Museum," a combination patient art studio/display space, as the intervention. During the visit, students interacted…

  3. Studio Mathematics: The Epistemology and Practice of Design Pedagogy as a Model for Mathematics Learning. WCER Working Paper No. 2005-3

    ERIC Educational Resources Information Center

    Shaffer, David Williamson

    2005-01-01

    This paper examines how middle school students developed understanding of transformational geometry through design activities in Escher's World, a computationally rich design experiment explicitly modeled on an architectural design studio. Escher's World was based on the theory of pedagogical praxis (Shaffer, 2004a), which suggests that preserving…

  4. Central radio galaxies in groups: cavities, bubbles and the history of AGN heating

    NASA Astrophysics Data System (ADS)

    Giacintucci, S.; Venturi, T.; Raychaudhury, S.; Vrtilek, J.

    2008-10-01

    E' noto che le regioni centrali degli ammassi e gruppi di galassie costituiscono un ambiente in cui gas caldo e plasma radioemittente proveniente dalle galassie dominanti interagiscono tra loro. In particolare, si pensa che la radioemissione dell'AGN centrale ed i suoi possibili cicli di attivita', siano strettamente legati alla presenza di cavita' e "bubbles" nel gas intergalattico. Si presentera' lo status di un progetto osservativo effettuato con il Giant Metrewave Radio Telescope (GMRT, India) su di un campione di 18 gruppi di galassie, osservati a tre frequenze radio (235 MHz, 325 MHz e 610 MHz). Lo studio della morfologia radio degli AGN centrali e la relativa analisi spettrale permettono di ottenere stime sull'eta' di questi oggetti, e sulla loro energia totale, che a loro volta sono in relazione con le proprieta' X dei gruppi stessi. Per tutti gli oggetti del campione sono disponibili osservazioni Chandra di proprieta'. Per due oggetti del campione, 4C+24.36 (al centro di AWM04) e NGC741 (al centro di RSOG17) verra' presentato uno studio dettagliato.

  5. Why a Paradigm Shift of "More than Human Ontologies" Is Needed: Putting to Work Poststructural and Posthuman Theories in Writers' Studio

    ERIC Educational Resources Information Center

    Kuby, Candace R.

    2017-01-01

    This manuscript puts to work "more than human ontologies" drawing on poststructural (rhizomatic) and posthumanist (intra-active) theories by plugging-in concepts with data produced in a second grade Writers' Studio to illustrate why a paradigm shift of "more than human ontologies" is needed. Specifically, how ways of…

  6. Mysteries of attraction: Giovanni Pico della Mirandola, astrology and desire.

    PubMed

    Rutkin, H Darrel

    2010-06-01

    Although in his later years Giovanni Pico della Mirandola (1463-1494) vehemently rejected astrology, he earlier used it in a variety of ways, but primarily to provide further evidence for positions to which he had arrived by other means. One such early use appears in his commentary on his friend Girolamo Benivieni's love poetry, the Canzone d'amore, of 1486-1487. In the passages discussed here, Pico presents an intensive Platonic natural philosophical analysis based on a deep astrologically informed understanding of human nature as he attempts to explain a perennial question, namely, why one person is attracted to a certain person (or people), and another to others. I will place this discussion of the mysteries of attraction and desire in historical perspective by tracing Pico's changing relationship to astrology during the course of his short but passionate life, and in historiographic perspective by revising Frances Yates's still influential views concerning Pico's contribution to Renaissance thought and his relationship with Marsilio Ficino.

  7. Teaching, Doing, and Sharing Project Management in a Studio Environment: The Development of an Instructional Design Open-Source Project Management Textbook

    ERIC Educational Resources Information Center

    Randall, Daniel L.; Johnson, Jacquelyn C.; West, Richard E.; Wiley, David A.

    2013-01-01

    In this article, the authors present an example of a project-based course within a studio environment that taught collaborative innovation skills and produced an open-source project management textbook for the field of instructional design and technology. While innovation plays an important role in our economy, and many have studied how to teach…

  8. Community-Partnered Project-Based Studio Pedagogy: Developing a Framework and Exploring the Impact on Faculty in Art and Design Higher Education

    ERIC Educational Resources Information Center

    Corn, Melanie E.

    2013-01-01

    Young would-be artists flock to art schools to learn from masters and immerse themselves in a study of the aesthetic histories, techniques, and theories that will inform their practices. However, the emergence of community-partnered project-based (CP) studio courses at many independent art colleges signals a fundamental shift in art and design…

  9. The Renaissance and the universal surgeon: Giovanni Andrea Della Croce, a master of traumatology.

    PubMed

    Di Matteo, Berardo; Tarabella, Vittorio; Filardo, Giuseppe; Viganò, Anna; Tomba, Patrizia; Marcacci, Maurilio

    2013-12-01

    All the medical knowledge of all time in one book, the universal and perfect manual for the Renaissance surgeon, and the man who wrote it. This paper depicts the life and works of Giovanni Andrea della Croce, a 16th Century physician and surgeon, who, endowed with true spirit of Renaissance humanism, wanted to teach and share all his medical knowledge through his opus magnum, titled "Universal Surgery Complete with All the Relevant Parts for the Optimum Surgeon". An extraordinary book which truly represents a defining moment and a founding stone for traumatology, written by a lesser known historical personality, but nonetheless the Renaissance Master of Traumatology.

  10. An investigation of components of the studio model and supplemental online materials, on student achievement and attitudes in science at the high school level

    NASA Astrophysics Data System (ADS)

    Faro, Salvatore T.

    With the increase of the student population, and meeting the demands driven by society public schools are scrambling to find ways to enhance learning and improve student achievement (Lee, 1993). Schools are examining and investing more time in the development of new approaches needed to strengthen, reach, and spark the interest of students both in and outside of classroom. One direction public schools are taking is to incorporate technology and more peer-directed group activities into instruction. Technological advancements today have enhanced the learning process by providing alternatives that stimulate the interest of the learner. Having these technology options available, allows the student to move at his or her own pace giving them time to reflect and make connections between what they already know and what they have learned in class. Using the conceptual framework of the Studio Model, which was developed in the 1980s at Rensselaer Polytechnic Institute for undergraduate and graduate level science courses, this study investigated the nature and extent to which the components in the Studio Model (cooperative collaboration and online materials) can be extended to the high school science level. A quasi-experimental, pretest-posttest design was selected for this study. Classes were randomly assigned to one of the four treatment groups, an experimental "Studio Model" condition in which students worked cooperatively and had access to online materials, an "Augmented Only" condition in which students had access to online materials only, a "Cooperative Only" condition in which students worked in cooperative groups only, and a "Control" condition in which students neither had access to online materials nor worked cooperatively. The data was collected for this study using 77 ninth-grade students studying Earth Science. Students were trained for a period of 20 weeks in the procedures of their particular treatment. To determine the effects of each treatment on student

  11. Learning in third spaces: community art studio as storefront university classroom.

    PubMed

    Timm-Bottos, Janis; Reilly, Rosemary C

    2015-03-01

    Third spaces are in-between places where teacher-student scripts intersect, creating the potential for authentic interaction and a shift in what counts as knowledge. This paper describes a unique community-university initiative: a third space storefront classroom for postsecondary students in professional education programs, which also functions as a community art studio for the surrounding neighborhood. This approach to professional education requires an innovative combination of theory, methods, and materials as enacted by the professionals involved and performed by the students. This storefront classroom utilizes collaborative and inclusive instructional practices that promote human and community development. It facilitates the use of innovative instructional strategies including art making and participatory dialogue to create a liminal learning space that reconfigures professional education. In researching the effectiveness of this storefront classroom, we share the voices of students who have participated in this third space as part of their coursework to underscore these principles and practices.

  12. Evaluation of the Impact of an Active-Learning Introductory Gemology Studio Course on Community College Students

    NASA Astrophysics Data System (ADS)

    Shekoyan, V.; Scal, R.

    2014-12-01

    A new active learning introductory gemology studio course with a lab component has been created at Queensborough Community College with the support of NSF TUES grant. Various pedagogical techniques that have shown efficacy at 4-year colleges have been implemented and adopted to improve student learning and course retention as well as to stimulate their interest in science and in STEM careers. The course covered broad range of STEM topics central to the gemology curriculum, including concepts from geology, mineralogy, physics and chemistry. Lectures and labs were linked. Students' misconceptions were addressed via guided laboratory activities in a studio-learning environment. The course used peer-based learning and problem solving by creating student groups that discussed observations and measurements. Discussion groups were required to observe, synthesize, and evaluate data for presentations. The goal was to empower student learning and peer-based teaching and to recruit early career, often non-STEM students, to earth science. Students were often prompted to engage in self-reflections on their learning. In this presentation we will present the analysis of the evaluation of the course and its impact on community college students. Some of the evaluation tools we have used are pre- and post- knowledge surveys, science attitude and belief surveys as well as a Geological Interest instrument. Parallel sections of traditionally taught lecture-only courses (taught by the same instructor) were utilized as a control group in the analysis. The pedagogical implications of the analysis on instruction and course design will be discussed as well.

  13. Sequence variations of the partially dominant DELLA gene Rht-B1c in wheat and their functional impacts

    PubMed Central

    Ma, Zhengqiang

    2013-01-01

    Rht-B1c, allelic to the DELLA protein-encoding gene Rht-B1a, is a natural mutation documented in common wheat (Triticum aestivum). It confers variation to a number of traits related to cell and plant morphology, seed dormancy, and photosynthesis. The present study was conducted to examine the sequence variations of Rht-B1c and their functional impacts. The results showed that Rht-B1c was partially dominant or co-dominant for plant height, and exhibited an increased dwarfing effect. At the sequence level, Rht-B1c differed from Rht-B1a by one 2kb Veju retrotransposon insertion, three coding region single nucleotide polymorphisms (SNPs), one 197bp insertion, and four SNPs in the 1kb upstream sequence. Haplotype investigations, association analyses, transient expression assays, and expression profiling showed that the Veju insertion was primarily responsible for the extreme dwarfing effect. It was found that the Veju insertion changed processing of the Rht-B1c transcripts and resulted in DELLA motif primary structure disruption. Expression assays showed that Rht-B1c caused reduction of total Rht-1 transcript levels, and up-regulation of GATA-like transcription factors and genes positively regulated by these factors, suggesting that one way in which Rht-1 proteins affect plant growth and development is through GATA-like transcription factor regulation. PMID:23918966

  14. Reducing medical students' stigmatization of people with chronic mental illness: a field intervention at the "living museum" state hospital art studio.

    PubMed

    Cutler, Janis L; Harding, Kelli J; Hutner, Lucy A; Cortland, Clarissa; Graham, Mark J

    2012-05-01

    The authors designed an intervention to reduce beginning medical students' stigmatization of people with chronic mental illness (CMI). Pre-clinical medical students visited a state psychiatric facility's "Living Museum," a combination patient art studio/display space, as the intervention. During the visit, students interacted with artist-guides who showed their work and discussed their experiences creating art. Students completed a self-assessment survey developed to measure attitudes and feelings toward people with CMI after half of the class visited the Living Museum, constituting a Visit/No-Visit cross-sectional comparison. Students who visited the Living Museum (N=64), as compared with those who did not visit (N=110), endorsed more positive attitudes toward people with CMI. Among the students who visited, however, those who reported having spoken individually with a patient-artist (N=44), paradoxically, indicated less-positive feelings toward people with CMI. An intervention in which pre-clinical medical students visited patient-artist guides in an art-studio setting generally improved students' attitudes toward people with CMI. Thus, nontraditional psychiatric settings offer a valuable adjunct to more traditional clinical settings to reduce stigma when introducing medical students to the field of psychiatry.

  15. Pathway results from the chicken data set using GOTM, Pathway Studio and Ingenuity softwares

    PubMed Central

    Bonnet, Agnès; Lagarrigue, Sandrine; Liaubet, Laurence; Robert-Granié, Christèle; SanCristobal, Magali; Tosser-Klopp, Gwenola

    2009-01-01

    Background As presented in the introduction paper, three sets of differentially regulated genes were found after the analysis of the chicken infection data set from EADGENE. Different methods were used to interpret these results. Results GOTM, Pathway Studio and Ingenuity softwares were used to investigate the three lists of genes. The three softwares allowed the analysis of the data and highlighted different networks. However, only one set of genes, showing a differential expression between primary and secondary response gave significant biological interpretation. Conclusion Combining these databases that were developed independently on different annotation sources supplies a useful tool for a global biological interpretation of microarray data, even if they may contain some imperfections (e.g. gene not or not well annotated). PMID:19615111

  16. Building America Case Study: Ground Source Heat Pump Research, TaC Studios Residence, Atlanta, Georigia (Fact Sheet)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    2014-09-01

    As part of the NAHB Research Center Industry Partnership, Southface partnered with TaC Studios, an Atlanta based architecture firm specializing in residential and light commercial design, on the construction of a new test home in Atlanta, GA in the mixed-humid climate. This home serves as a residence and home office for the firm's owners, as well as a demonstration of their design approach to potential and current clients. Southface believes the home demonstrates current best practices for the mixed-humid climate, including a building envelope featuring advanced air sealing details and low density spray foam insulation, glazing that exceeds ENERGY STARmore » requirements, and a high performance heating and cooling system. Construction quality and execution was a high priority for TaC Studios and was ensured by a third party review process. Post construction testing showed that the project met stated goals for envelope performance, an air infiltration rate of 2.15 ACH50. The homeowner's wished to further validate whole house energy savings through the project's involvement with Building America and this long-term monitoring effort. As a Building America test home, this home was evaluated to detail whole house energy use, end use loads, and the efficiency and operation of the ground source heat pump and associated systems. Given that the home includes many non-typical end use loads including a home office, pool, landscape water feature, and other luxury features not accounted for in Building America modeling tools, these end uses were separately monitored to determine their impact on overall energy consumption.« less

  17. Unusual morphological features in a presumably Neolithic individual from Riparo della Rossa, Serra San Quirico (Ancona, Italy).

    PubMed

    D'Amore, G; Pacciani, E; Frederic, P; Caramella Crespi, V

    2007-01-01

    The present study describes human skeletal remains from Riparo della Rossa, a rock shelter in the Marche region (Central Italy). The remains consist of a cranial vault and a few non-articulated postcranial bones, possibly belonging to the same adult individual. As the cranial vault showed some morphological features that are unusual for a modern human (marked prominence of the supraorbital region, very prominent nasal bones and rather high thickness of the vault), an accurate anthropological analysis and quantification of the antiquity of the bones were required. The remains were dated with two different absolute dating methods, AMS (14)C and (235)U-(231)Pa non-destructive gamma-ray spectrometry (NDGRS), which produced discordant results: the uncalibrated (14)C dating produced 5690 +/- 80 BP for the cranial vault and 6110 +/- 80 BP for the clavicle; the NDGRS dating produced 10,000 +/- 3000 BP for the cranial vault. The sex discriminant morphological characters on the skull are not unequivocal, though the masculine ones appear more evident. The aims of the present paper are: to provide a morphological and metric description of the remains; to interpret their unusual morphological features; to attempt to attribute them to male or female sex and to one of the possible prehistoric cultural groups, according to dating results (Upper Palaeolithic, Mesolithic or Neolithic). The attribution was obtained by a Bayesian procedure taking into account the reliability of the combined information of morphological/metric features and absolute dating results. The results suggest that the Riparo della Rossa remains are best attributed to a male individual of the Neolithic age.

  18. Lo Gnomone Clementino Astronomia Meridiana in Basilica

    NASA Astrophysics Data System (ADS)

    Sigismondi, Costantino

    2014-05-01

    Costruito per chiara volontà del papa 70 anni dopo il caso Galileo, lo Gnomone Clementino è un grande telescopio solare che non fa uso di lenti a 92 anni dall’invenzione del cannocchiale. Queste due caratteristiche basterebbero da sole a giustificare l’interesse verso questo strumento. L’astronomia meridiana è alla base dell’astrometria e dell’astrofisica moderna. Lo Gnomone Clementino sta oggi all’astronomia, come il veliero “Amerigo Vespucci” sta alla Marina Italiana. E’ possibile svolgere ogni genere di osservazione e studio su questo strumento, e dal 2002 vi tengo lezioni teorico-pratiche del corso di Storia dell’Astronomia e La Terra nel Sistema Solare della Sapienza, Università di Roma, Facoltà di Lettere e Filosofia. Questo testo aggiunge alcuni tasselli alla ricerca storica sulla meridiana, appoggiandosi, com’è naturale, sulle spalle di giganti che mi hanno preceduto in questi studi. In particolare la misura dell’azimut della meridiana, ed il suo inquadramento tra gli strumenti simili ed alcuni studi di astrometria sui dati del 1701-1703 di Bianchini, che sono apparsi fin’ora soltanto su riviste specializzate ed in Inglese vengono qui proposti in Italiano e semplificati, per valorizzare sempre più questa straordinaria opera d’arte e di scienza.

  19. Numerical analysis of natural ventilation system in a studio apartment in Bangladesh

    NASA Astrophysics Data System (ADS)

    Kabir, K. M. Ariful; Hasan, Md. Rakibul; Khan, Md. Abdul Hakim

    2017-07-01

    The study of temperature and air flow for natural ventilation system has been investigated numerically. A finite element model for studio apartment was developed with the aim of achieving detail energy allocation in the real buildings during the transient process in the walls and internal air. A tool of computational fluid dynamics (CFD) is employed to assist the process. In the tropical regions most of the energy is consumed by the heating, cooling and ventilation appliances. Therefore, the optimize ventilation system will be a suitable and valid option for the saving of energy from the household sector to increase cooling performance and ensuring thermal comfort as well. A mathematical exploration is carried out on full scale dwelling and small scale model and indication is given on the relevance of such a comparison. Calculations are carried out with household heat sources for calm and windy period, but without any human. As expected, for windy periods, the wind is the main driving force behind the internal air flow. However, in calm periods for unsteady flow the internal airflow looks like more complexes through observation.

  20. Computer graphics synthesis for inferring artist studio practice: an application to Diego Velázquez's Las Meninas[

    NASA Astrophysics Data System (ADS)

    Stork, David G.; Furuichi, Yasuo

    2009-02-01

    Diego Velázquez's Las meninas (1656) has been called by some art experts "the most important painting of the 17th century," "a theology of painting," and even "the world's greatest painting"; it has been the subject of intensive study. The work depicts a complex scene in the Alcázar palace of King Philip IV of Spain, and includes mirror reflections of the king and queen, apparently standing in place of the viewer, as well as the artist himself standing before an enormous canvas on an easel. Nevertheless, questions remain about the studio and the proper viewing configuration: Is the artist looking toward the perspectivally correct position of the viewer in the museum space (center of projection), outside the picture space? Does the perspectivally correct position correspond to the locations of the king and queen seen reflected in the mirror? Is the bright illumination on the king and queen (as revealed in the mirror) consistent with the lighting in the tableau itself? We addressed these questions in a new way: by building a full computer graphics model of the figures and tableau as well as the viewer's space outside the painting. In our full model, the painting itself is represented as a translucent window onto which the picture space is projected toward the center of projection, that is, the viewer. Our geometric and (new) lighting evidence confirm Janson's and Snyder's contention that the plane mirror on the back wall reflects the other side of the large painting depicted within the tableau, not the king and queen themselves in the studio. We believe our computer graphics synthesis of both the tableau within the painting and the viewer's space in the real world is the first of its kind to address such problems in the history of art.

  1. The growth history of the Lago Della Vacca (Southern Adamello Massive, Italy) intrusion from field observations, thermal and rheological modelling

    NASA Astrophysics Data System (ADS)

    Rust, A.; Annen, C.; Blundy, J. D.; Caricchi, L.

    2010-12-01

    The Lago Della Vacca granitoid is an intrusive body emplaced at about 4-6 km in up to 1 My. The core of the body is characterised by the presence of dyke-like structures, enclave-swarms and randomly distributed enclaves, which appear undeformed. Enclaves become oblate with the short axis perpendicular to the foliation, which, in turn follows the margin of the plutonic body (John and Blundy, 1993). Geothermometry and experimental data have been used to constrain the temperature of injection of the mafic component (1273-1323 K), the temperature of the host granitic magma (1173-1223), and to characterise the evolution of crystallinity with temperature for both magmas (Blundy and Sparks, 1992). Based on these data thermal and rheological modelling have been combined to interpret the growth and deformation history of the Lago della Vacca intrusive body. The pluton was modeled as a series of incrementally emplaced nested cylinders with 1D-cylindrical conductive heat transfer. The evolution of temperature and melt fraction distribution in the pluton and country rock were determined and used as input parameters for the rheological modelling. The rheology of each magma depends on the viscosity of the melt and, more importantly, on crystallinity. Field observations suggest that the mafic magma was injected as dykes. Their partial or total disaggregation produced mafic enclaves. The presence of randomly distributed enclaves in the core of Lago Della Vacca body indicates that convection was active in this portion of the intrusion. The undeformed nature of the enclaves in this region also implies that the contrast in temperature between host magma and mafic material produced a sudden (hours) rheological inversion with the mafic magma becoming more viscous than the felsic end-member. In these conditions, the enclaves would be transported passively by the felsic-host without suffering any substantial deformation. Thermal modelling indicates that to maintain the core of the pluton

  2. Implement trigger for a NI data acquisition card PCI 5105 in the measurement studio development environment for a high speed demodulator based on fiber Fabry-Pérot tunable filter (FFP-TF)

    NASA Astrophysics Data System (ADS)

    Zhang, Hongtao; Yang, Shangming; Fan, Lingling; Wang, Pengfei; Zhao, Xilin; Wang, Zhenhua; Cui, Hong-Liang

    2010-04-01

    In this paper we report a scheme of low-cost, small-size differential electrical converter to change analog trigger signals into digital trigger signals. This converter successfully resolves the incompatibility between the digital trigger mode of NI (National Instruments) data acquisition card PCI 5105 in Measurement Studio development environment for a demodulator and the requirement from instability of spectra of fiber Bragg grating (FBG) sensors. The instability is caused by intrinsic drifts of FFP-TF inside this high speed demodulator. The obtained results of frequency response about the converter have clearly demonstrated that this method is effective when the frequency of trigger signal is less than 3,000 Hz. This converter can satisfy the current requirements of demodulator based on FFP-TF, since mostly actual working scanning frequency of FFP-TF is less than 1,000 Hz. This method may be recommended to resolve similar problems for other NI customers who have developed their data acquisition system based on Measurement Studio.

  3. Lungo le vie di pellegrinaggio: la lezione astronomica di Gerberto a San Michele della Chiusa

    NASA Astrophysics Data System (ADS)

    Paladino, Laura C.

    A pilgrim on the trails of the Earth: that's how Gerbertus appears to us in the years preceding his pontificate as well in those, brief and intense, in which he was Pope. An ardent pilgrim of faith moved at the same time by vast intellectual interests that allowed him to come into contact with the most important schools of the time, of any cultural tradition; a pilgrim full of love, willing to transmit the enormous heritage of faith and knowledge of which he was custodian. The presence of the illustrious Benedictine is not explicitly documented in the Abbey of San Michele della Chiusa, but the signs of its cultural and ideological influence are evident both in historical memory as in the artistical vestiges of the Sacra: we investigate here, this presence, authoritative, original and versatile, to outline another aspect, still little investigated, of the lesson of Gerbert, monk, scientist, teacher and pastor.

  4. Poisoning histories in the Italian renaissance: The case of Pico Della Mirandola and Angelo Poliziano.

    PubMed

    Gallello, Gianni; Cilli, Elisabetta; Bartoli, Fulvio; Andretta, Massimo; Calcagnile, Lucio; Pastor, Agustin; de la Guardia, Miguel; Serventi, Patrizia; Marino, Alberto; Benazzi, Stefano; Gruppioni, Giorgio

    2018-05-01

    Giovanni Pico della Mirandola and Angelo Poliziano were two of the most important humanists of the Italian Renaissance. They died suddenly in 1494 and their deaths have been for centuries a subject of debate. The exhumation of their remains offered the opportunity to study the cause of their death through a multidisciplinary research project. Anthropological analyses, together with documentary evidences, radiocarbon dating and ancient DNA analysis supported the identification of the remains attributed to Pico. Macroscopic examination did not reveal paleopathological lesions or signs related to syphilis. Heavy metals analysis, carried out on bones and mummified tissues, showed that in Pico's remains there were potentially lethal levels of arsenic, supporting the philosopher's poisoning theory reported by documentary sources. The arsenic concentrations obtained from analysis of Poliziano's remains, are probably more related to an As chronic exposure or diagenetic processes rather than poisoning. Copyright © 2018 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  5. A scientific approach to the characterization of the painting materials of Fra Mattia della Robbia polychrome terracotta altarpiece

    NASA Astrophysics Data System (ADS)

    Amadori, M. L.; Barcelli, S.; Casoli, A.; Mazzeo, R.; Prati, S.

    2013-12-01

    During the last restoration (2008-2011) of the polychrome terracotta altarpiece called Coronation of Virgin between Saints Rocco, Sebastian, Peter martyr and Antonio abbot, located in the collegiate church of S. Maria Assunta in Montecassiano (Macerata, Italy), scientific investigations were carried out to acquire detailed information about the painting technique. The identification of materials allowed a correct restoration. The altarpiece is almost entirely realized by Marco della Robbia (Fra Mattia), dates back to the first half of the XVI century and represents an interesting example of painted terracotta produced by using two different techniques: glazed polychrome terracotta and the "cold painting" technique. The characterization of the samples' material constituents was obtained by analysing the cross-sections and the fragments by different techniques (optical, SEM-EDS and ATR-FTIR microscopy as well as GC-MS), as the real nature of a component is often difficult to assess with one single technique. The optical microscope examination of paint cross-sections shows the presence of many layers, indicating the complexity of the paint stratigraphic morphologies. The original polychromy of della Robbia's masterpiece is constituted of cinnabar, red lake, red lead, orpiment, red ochre, lead white, lead tin yellow, green earth and raw umber. Two different types of gilding technique have been distinguished. The first one presents a glue mordant, and the second one shows an oil mordant composed by a mixture of red lead, red ochre, cinnabar and orpiment. The GC-MS analysis allowed the characterisation of linseed oil and a mixture of animal glue and egg as binding media stratigraphically located by the use of ATR-FTIR mapping microscopy. The analytical results of the painted terracotta integrated investigations show that original technique adopted is characterised by the application of pigments in an oil-binding medium directly applied on the substrates, probably treated

  6. Release of the repressive activity of rice DELLA protein SLR1 by gibberellin does not require SLR1 degradation in the gid2 mutant.

    PubMed

    Ueguchi-Tanaka, Miyako; Hirano, Ko; Hasegawa, Yasuko; Kitano, Hidemi; Matsuoka, Makoto

    2008-09-01

    The rice (Oryza sativa) DELLA protein SLR1 acts as a repressor of gibberellin (GA) signaling. GA perception by GID1 causes SLR1 protein degradation involving the F-box protein GID2; this triggers GA-associated responses such as shoot elongation and seed germination. In GA-insensitive and GA biosynthesis mutants, SLENDER RICE1 (SLR1) accumulates to high levels, and the severity of dwarfism is usually correlated with the level of SLR1 accumulation. An exception is the GA-insensitive F-box mutant gid2, which shows milder dwarfism than mutants such as gid1 and cps even though it accumulates higher levels of SLR1. The level of SLR1 protein in gid2 was decreased by loss of GID1 function or treatment with a GA biosynthesis inhibitor, and dwarfism was enhanced. Conversely, overproduction of GID1 or treatment with GA(3) increased the SLR1 level in gid2 and reduced dwarfism. These results indicate that derepression of SLR1 repressive activity can be accomplished by GA and GID1 alone and does not require F-box (GID2) function. Evidence for GA signaling without GID2 was also provided by the expression behavior of GA-regulated genes such as GA-20oxidase1, GID1, and SLR1 in the gid2 mutant. Based on these observations, we propose a model for the release of GA suppression that does not require DELLA protein degradation.

  7. Occupational exposure to polybrominated diphenyl ethers (PBDEs) and other flame retardant foam additives at gymnastics studios: Before, during and after the replacement of pit foam with PBDE-free foams.

    PubMed

    Ceballos, Diana M; Broadwater, Kendra; Page, Elena; Croteau, Gerry; La Guardia, Mark J

    2018-07-01

    Coaches spend long hours training gymnasts of all ages aided by polyurethane foam used in loose blocks, mats, and other padded equipment. Polyurethane foam can contain flame retardant additives such as polybrominated diphenyl ethers (PBDEs), to delay the spread of fires. However, flame retardants have been associated with endocrine disruption and carcinogenicity. The National Institute for Occupational Safety and Health (NIOSH) evaluated employee exposure to flame retardants in four gymnastics studios utilized by recreational and competitive gymnasts. We evaluated flame retardant exposure at the gymnastics studios before, during, and after the replacement of foam blocks used in safety pits with foam blocks certified not to contain several flame retardants, including PBDEs. We collected hand wipes on coaches to measure levels of flame retardants on skin before and after their work shift. We measured flame retardant levels in the dust on window glass in the gymnastics areas and office areas, and in the old and new foam blocks used throughout the gymnastics studios. We found statistically higher levels of 9 out of 13 flame retardants on employees' hands after work than before, and this difference was reduced after the foam replacement. Windows in the gymnastics areas had higher levels of 3 of the 13 flame retardants than windows outside the gymnastics areas, suggesting that dust and vapor containing flame retardants became airborne. Mats and other padded equipment contained levels of bromine consistent with the amount of brominated flame retardants in foam samples analyzed in the laboratory. New blocks did not contain PBDEs, but did contain the flame retardants 2-ethylhexyl 2,3,4,5-tetrabromobenzoate and 2-ethylhexyl 2,3,4,5-tetrabromophthalate. We conclude that replacing the pit foam blocks eliminated a source of PBDEs, but not 2-ethylhexyl 2,3,4,5-tetrabromobenzoate and 2-ethylhexyl 2,3,4,5-tetrabromophthalate. We recommend ways to further minimize employee exposure

  8. Using Optical Coherence Tomography to Reveal the Hidden History of The Landsdowne Virgin of the Yarnwinder by Leonardo da Vinci and Studio.

    PubMed

    Targowski, Piotr; Iwanicka, Magdalena; Sylwestrzak, Marcin; Frosinini, Cecilia; Striova, Jana; Fontana, Raffaella

    2018-06-18

    Optical coherence tomography (OCT) was used for non-invasive examination of a well-known, yet complex, painting from the studio of Leonardo da Vinci in combination with routine imaging in various bands of electromagnetic radiation. In contrast with these techniques, OCT provides depth-resolved information. Three post-processing modalities were explored: cross-sectional views, maps of scattering from given depths, and their 3D models. Some hidden alterations of the painting owing to past restorations were traced: retouching and overpainting with their positioning within varnish layers as well as indications of a former transfer to canvas. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Physically-based quantitative analysis of soil erosion induced by heavy rainfall on steep slopes

    NASA Astrophysics Data System (ADS)

    Della Sala, Maria; Cuomo, Sabatino; Novità, Antonio

    2014-05-01

    -southern Italy. Proc. of the first Italian Workshop on Landslides, 8-10 June 2009 Naples, Italy, vol 1. Studio Editoriale Doppiavoce, Naples, pp 43-51. Cascini, L., Sorbino, G., Cuomo, S., Ferlisi, S. (2013). Seasonal effects of rainfall on the shallow pyroclastic deposits of the Campania region (southern Italy). Landslides, 1-14, DOI: 10.1007/s10346-013-0395-3. Cuomo S., Della Sala M. (2013a). Spatially distributed analysis of shallow landslides and soil erosion induced by rainfall. (submitted to Natural Hazards). Cuomo, S., Della Sala, M. (2013b). Rainfall-induced infiltration, runoff and failure in steep unsaturated shallow soil deposits. Engineering Geology. 162, 118-127. Cuomo, S., Della Sala, M., Novità A. (2013). Physically-based modeling of soil erosion induced by rainfall on steep slopes. (submitted to Geomorphology).

  10. [Cyberstalking among Italian nurses: a large multicentric study].

    PubMed

    Comparcini, Dania; Simonetti, Valentina; Lupo, Roberto; Galli, Francesco; Bocij, Paul; Cicolini, Giancarlo

    2016-01-01

    Determinare la prevalenza di cyberstalking tra gli infermieri italiani e valutare il livello di ansia e depressione nelle vittime. Da aprile a settembre 2014 è stato condotto uno studio multicentrico trasversale in un campione di infermieri italiani (n=997) utilizzando il questionario "Cyberstalking" per analizzare il fenomeno del cyberstalking. Ai partecipanti, che si sono autodefinite vittime di cyberstalking, è stato chiesto anche di compilare gli strumenti "Beck Depression Inventory" e "State-Trait Anxiety Inventory" per valutare, rispettivamente, i livelli di depressione ed ansia. La prevalenza di cyberstalking tra gli infermieri italiani è risultata pari al 23.3%. Il 42.7% ha dovuto cambiare il proprio stile di vita e lavorativo. Il cyberstalker era prevalentemente di sesso maschile (52%) e, nel 49% dei casi, era un paziente. Le vittime hanno riferito moderati livelli di ansia (media=28.4, SD=23.2) e depressione (media=92.7, SD=18.3); i risultati hanno mostrato un aumento dei livelli di depressione negli infermieri esperti nell'utilizzo del computer, gestori di siti web o blog, e una correlazione negativa tra il livello di ansia e gli infermieri esperti (r = -0.264). Il cyberstalking è un fenomeno che si riscontra frequentemente tra gli infermieri. Il rapporto infermiere - paziente gioca un ruolo centrale nello sviluppo del fenomeno e le vittime hanno riferito disordini correlati allo stress che influenzano la vita lavorativa. Questi risultati preliminari potrebbero sensibilizzare, i dirigenti ospedalieri, la politica e i centri antiviolenza al fine di sviluppare strategie risolutiv.

  11. Characterization of the procera Tomato Mutant Shows Novel Functions of the SlDELLA Protein in the Control of Flower Morphology, Cell Division and Expansion, and the Auxin-Signaling Pathway during Fruit-Set and Development1[C][W

    PubMed Central

    Carrera, Esther; Ruiz-Rivero, Omar; Peres, Lazaro Eustaquio Pereira; Atares, Alejandro; Garcia-Martinez, Jose Luis

    2012-01-01

    procera (pro) is a tall tomato (Solanum lycopersicum) mutant carrying a point mutation in the GRAS region of the gene encoding SlDELLA, a repressor in the gibberellin (GA) signaling pathway. Consistent with the SlDELLA loss of function, pro plants display a GA-constitutive response phenotype, mimicking wild-type plants treated with GA3. The ovaries from both nonemasculated and emasculated pro flowers had very strong parthenocarpic capacity, associated with enhanced growth of preanthesis ovaries due to more and larger cells. pro parthenocarpy is facultative because seeded fruits were obtained by manual pollination. Most pro pistils had exserted stigmas, thus preventing self-pollination, similar to wild-type pistils treated with GA3 or auxins. However, Style2.1, a gene responsible for long styles in noncultivated tomato, may not control the enhanced style elongation of pro pistils, because its expression was not higher in pro styles and did not increase upon GA3 application. Interestingly, a high percentage of pro flowers had meristic alterations, with one additional petal, sepal, stamen, and carpel at each of the four whorls, respectively, thus unveiling a role of SlDELLA in flower organ development. Microarray analysis showed significant changes in the transcriptome of preanthesis pro ovaries compared with the wild type, indicating that the molecular mechanism underlying the parthenocarpic capacity of pro is complex and that it is mainly associated with changes in the expression of genes involved in GA and auxin pathways. Interestingly, it was found that GA activity modulates the expression of cell division and expansion genes and an auxin signaling gene (tomato AUXIN RESPONSE FACTOR7) during fruit-set. PMID:22942390

  12. The Palazzo della Ragione in Padua: Representation and Communication of Art, Architecture, and Astrology of a Civic Monument

    NASA Astrophysics Data System (ADS)

    Borgherini, M.; Garbin, E.

    2011-06-01

    Eight centuries of the history of art and of Padua's scientific and technological culture deposited on the stones and frescoes of its Palace of Law ("Palazzo della Ragione") make this great work of urban architecture a part of the city's collective identity. This "palimpsest", legible only to a restricted circle of specialists, should be accessible to a vaster public interested in understanding this object symbol of local culture. The project planned for interactive exploration on the web is a series of digital models, employing tomographic-endoscopic visualizations and, in future, multi-resolution images. The various models devised allow the visitor to superimpose the Palace's current conditions on the various transformations undergone over the centuries. Similarly, comparisons can be made between the astrological fresco cycle with maps of the heavens, cosmological hypotheses, ancient and contemporary astrological treatises, and the related exchange of knowledge between the Orient and the Occident.

  13. A Gibberellin-Mediated DELLA-NAC Signaling Cascade Regulates Cellulose Synthesis in Rice.

    PubMed

    Huang, Debao; Wang, Shaogan; Zhang, Baocai; Shang-Guan, Keke; Shi, Yanyun; Zhang, Dongmei; Liu, Xiangling; Wu, Kun; Xu, Zuopeng; Fu, Xiangdong; Zhou, Yihua

    2015-06-01

    Cellulose, which can be converted into numerous industrial products, has important impacts on the global economy. It has long been known that cellulose synthesis in plants is tightly regulated by various phytohormones. However, the underlying mechanism of cellulose synthesis regulation remains elusive. Here, we show that in rice (Oryza sativa), gibberellin (GA) signals promote cellulose synthesis by relieving the interaction between SLENDER RICE1 (SLR1), a DELLA repressor of GA signaling, and NACs, the top-layer transcription factors for secondary wall formation. Mutations in GA-related genes and physiological treatments altered the transcription of CELLULOSE SYNTHASE genes (CESAs) and the cellulose level. Multiple experiments demonstrated that transcription factors NAC29/31 and MYB61 are CESA regulators in rice; NAC29/31 directly regulates MYB61, which in turn activates CESA expression. This hierarchical regulation pathway is blocked by SLR1-NAC29/31 interactions. Based on the results of anatomical analysis and GA content examination in developing rice internodes, this signaling cascade was found to be modulated by varied endogenous GA levels and to be required for internode development. Genetic and gene expression analyses were further performed in Arabidopsis thaliana GA-related mutants. Altogether, our findings reveal a conserved mechanism by which GA regulates secondary wall cellulose synthesis in land plants and provide a strategy for manipulating cellulose production and plant growth. © 2015 American Society of Plant Biologists. All rights reserved.

  14. Piero della Francesca's Sky in The Dream of Constantine

    NASA Astrophysics Data System (ADS)

    Valerio, V.

    2011-06-01

    The recent restoration of the frescoes by Piero della Francesca in the Church of San Francesco in Arezzo has made to appear on the background of the scene of Constantine's dream a number of stars. They are clearly painted with the intention to illustrate a sort of "natural" sky. In 2001 Anna Maria Maetzke recognized in a group of stars the constellation of the Ursa Minor, but so far no further study has been carried on to find any relation between the painted and the true sky. In this paper I show the existence of more constellations in the fresco, which are hardly detectable due to the mirror representation of the starry sky. Such a mirror image, as the Universe was seen from the outside, has a Greek origin and this kind of representation was introduced in Western Europe not only in celestial globes but also in star maps. This discovery leads to consider that Piero had at his disposal either a globe or a map which he reproduced on the fresco. My hypothesis is that a star map might be supplied to Piero by the astronomer Regiomontanus who was in Italy since 1461 following the Cardinal Bessarion in his journey from Wien to Rome. In 1463, Cardinal Bessarion was named papal legate to Venice and in July of the same year he leaved Rome together with Regiomontanus to reach Ferrara and Venice. The road to Venice crossed Umbria nearby Sansepolcro, Piero's birthplace not far from Arezzo. The trip took more than two weeks due to a stop before crossing the Apennines because the plague in Ferrara. Bessarion and Regiomontanus might have met Piero who was painting the cycle of frescoes in Arezzo and supplied him with a star map. Unfortunately, due to the lack of the horizon and any right line in the scene it is not possible to detect the latitude of the place corresponding to the painted sky.

  15. Chromosomenindividualität or Entmischung? The debate between Paolo Della Valle and Edmund B. Wilson.

    PubMed

    Volpone, Alessandro

    2015-01-01

    At the beginning of the twentieth century, the Italian cytologist Paolo Della Valle developed a theory of instable chromosomes (teoria dei cromosomi labili). He radically criticized the so-called Sutton-Boveri hypothesis (Martins and Martins, Genetics and Molecular Biology, 22:261-271, 1999), focusing on numerical constancy in the species and individuality. On the basis of bibliographical review and personal observations, he maintained that the chromosomes were neither stable bodies, nor permanent structures, but transitory cellular materials, resulting from the periodical rearrangement of the chromatin during the cell division. German and English-speaking biologists reacted. The paper shows some content of the argumentations used by Thomas H. Montgomery and especially Edmund B. Wilson. The discussion was characterized by the same data which is interpretedby different scholars in different ways. And the point is that no one of them had the decisive test to demonstrate his own point of view. Wilson simply invoked on his behalf a certain 'common sense', defending at least a 'high degree of constancy'. The debate waned along with the reception of Morgan's chromosome theory of heredity, but only the advent of molecular biology definitively stated the nature of chromosomes as permanent structures of the cell.

  16. A Gibberellin-Mediated DELLA-NAC Signaling Cascade Regulates Cellulose Synthesis in Rice[OPEN

    PubMed Central

    Huang, Debao; Wang, Shaogan; Zhang, Baocai; Shang-Guan, Keke; Shi, Yanyun; Zhang, Dongmei; Liu, Xiangling; Wu, Kun; Xu, Zuopeng; Fu, Xiangdong; Zhou, Yihua

    2015-01-01

    Cellulose, which can be converted into numerous industrial products, has important impacts on the global economy. It has long been known that cellulose synthesis in plants is tightly regulated by various phytohormones. However, the underlying mechanism of cellulose synthesis regulation remains elusive. Here, we show that in rice (Oryza sativa), gibberellin (GA) signals promote cellulose synthesis by relieving the interaction between SLENDER RICE1 (SLR1), a DELLA repressor of GA signaling, and NACs, the top-layer transcription factors for secondary wall formation. Mutations in GA-related genes and physiological treatments altered the transcription of CELLULOSE SYNTHASE genes (CESAs) and the cellulose level. Multiple experiments demonstrated that transcription factors NAC29/31 and MYB61 are CESA regulators in rice; NAC29/31 directly regulates MYB61, which in turn activates CESA expression. This hierarchical regulation pathway is blocked by SLR1-NAC29/31 interactions. Based on the results of anatomical analysis and GA content examination in developing rice internodes, this signaling cascade was found to be modulated by varied endogenous GA levels and to be required for internode development. Genetic and gene expression analyses were further performed in Arabidopsis thaliana GA-related mutants. Altogether, our findings reveal a conserved mechanism by which GA regulates secondary wall cellulose synthesis in land plants and provide a strategy for manipulating cellulose production and plant growth. PMID:26002868

  17. A rice gid1 suppressor mutant reveals that gibberellin is not always required for interaction between its receptor, GID1, and DELLA proteins.

    PubMed

    Yamamoto, Yuko; Hirai, Takaaki; Yamamoto, Eiji; Kawamura, Mayuko; Sato, Tomomi; Kitano, Hidemi; Matsuoka, Makoto; Ueguchi-Tanaka, Miyako

    2010-11-01

    To investigate gibberellin (GA) signaling using the rice (Oryza sativa) GA receptor GIBBERELLIN-INSENSITIVE DWARF1 (GID1) mutant gid1-8, we isolated a suppressor mutant, Suppressor of gid1-1 (Sgd-1). Sgd-1 is an intragenic mutant containing the original gid1-8 mutation (L45F) and an additional amino acid substitution (P99S) in the loop region. GID1(P99S) interacts with the rice DELLA protein SLENDER RICE1 (SLR1), even in the absence of GA. Substitution of the 99th Pro with other amino acids revealed that substitution with Ala (P99A) caused the highest level of GA-independent interaction. Physicochemical analysis using surface plasmon resonance revealed that GID1(P99A) has smaller K(a) (association) and K(d) (dissociation) values for GA(4) than does wild-type GID1. This suggests that the GID1(P99A) lid is at least partially closed, resulting in both GA-independent and GA-hypersensitive interactions with SLR1. One of the three Arabidopsis thaliana GID1s, At GID1b, can also interact with DELLA proteins in the absence of GA, so we investigated whether GA-independent interaction of At GID1b depends on a mechanism similar to that of rice GID1(P99A). Substitution of the loop region or a few amino acids of At GID1b with those of At GID1a diminished its GA-independent interaction with GAI while maintaining the GA-dependent interaction. Soybean (Glycine max) and Brassica napus also have GID1s similar to At GID1b, indicating that these unique GID1s occur in various dicots and may have important functions in these plants.

  18. Hazard-evaluation and technical-assistance report No. ta-77-68, McDaniel Art Studio, Cincinnati, Ohio

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kronoveter, K.J.

    1978-06-01

    In response to a request from the McDaniel Art Studio, located in Cincinnati, Ohio, an investigation was made of possible hazardous working conditions at the site, specifically the exposure to dust during sculpturing. Air sampling revealed potential dust exposures as high as 50 mg/m3 of total dust while using a powered disc grinder to sculpt. The sculpting process involved grinding with a 6-inch electric disc grinder or using such hand tools as files and chisels. The sculptor used primarily limestone, marble, talc, and onyx, working about 6 hours per day. The talc sculpting stone showed the presence of asbestos onmore » bulk analysis. The sculptor wore safety glasses with side shields and an appropriate, approved respirator. An industrial vacuum cleaner was used for dust cleanup. The author recommends that the sculptor continue to use the NIOSH approved respirator and that, if possible, the disc grinder not be used on potential asbestos sources such as serpentine and talc. Wet working of the stone would reduce the dust levels significantly. Several precautionary measures are listed from a publication dealing with the health risks associated with common art and hobby materials.« less

  19. Simulation of cold magnetized plasmas with the 3D electromagnetic software CST Microwave Studio®

    NASA Astrophysics Data System (ADS)

    Louche, Fabrice; Křivská, Alena; Messiaen, André; Wauters, Tom

    2017-10-01

    Detailed designs of ICRF antennas were made possible by the development of sophisticated commercial 3D codes like CST Microwave Studio® (MWS). This program allows for very detailed geometries of the radiating structures, but was only considering simple materials like equivalent isotropic dielectrics to simulate the reflection and the refraction of RF waves at the vacuum/plasma interface. The code was nevertheless used intensively, notably for computing the coupling properties of the ITER ICRF antenna. Until recently it was not possible to simulate gyrotropic medias like magnetized plasmas, but recent improvements have allowed programming any material described by a general dielectric or/and diamagnetic tensor. A Visual Basic macro was developed to exploit this feature and was tested for the specific case of a monochromatic plane wave propagating longitudinally with respect to the magnetic field direction. For specific cases the exact solution can be expressed in 1D as the sum of two circularly polarized waves connected by a reflection coefficient that can be analytically computed. Solutions for stratified media can also be derived. This allows for a direct comparison with MWS results. The agreement is excellent but accurate simulations for realistic geometries require large memory resources that could significantly restrict the possibility of simulating cold plasmas to small-scale machines.

  20. Novel method to detect microRNAs using chip-based QuantStudio 3D digital PCR.

    PubMed

    Conte, Davide; Verri, Carla; Borzi, Cristina; Suatoni, Paola; Pastorino, Ugo; Sozzi, Gabriella; Fortunato, Orazio

    2015-10-23

    Research efforts for the management of cancer, in particular for lung cancer, are directed to identify new strategies for its early detection. MicroRNAs (miRNAs) are a new promising class of circulating biomarkers for cancer detection, but lack of consensus on data normalization methods has affected the diagnostic potential of circulating miRNAs. There is a growing interest in techniques that allow an absolute quantification of miRNAs which could be useful for early diagnosis. Recently, digital PCR, mainly based on droplets generation, emerged as an affordable technology for precise and absolute quantification of nucleic acids. In this work, we described a new interesting approach for profiling circulating miRNAs in plasma samples using a chip-based platform, the QuantStudio 3D digital PCR. The proposed method was validated using synthethic oligonucleotide at serial dilutions in plasma samples of lung cancer patients and in lung tissues and cell lines. Given its reproducibility and reliability, our approach could be potentially applied for the identification and quantification of miRNAs in other biological samples such as circulating exosomes or protein complexes. As chip-digital PCR becomes more established, it would be a robust tool for quantitative assessment of miRNA copy number for diagnosis of lung cancer and other diseases.

  1. Multielemental analysis of tissues from Cangrande della Scala, Prince of Verona, in the 14th century.

    PubMed

    Apostoli, Pietro; De Palma, Giuseppe; Catalani, Simona; Bortolotti, Federica; Tagliaro, Franco

    2009-01-01

    Cangrande della Scala, Prince of Verona (Italy), died suddenly shortly after his triumph in the battle of Treviso (July 18, 1329). Thus, in the frame of a multidisciplinary paleo-pathological study, we carried out a multielemental analysis on the Prince's tissue specimens, including hair, liver, muscle, and bone, in order to characterize a multitissue profile of metallic elements in a nobleman of the 14th century. Biological specimens were analyzed by inductively coupled plasma-mass spectrometry. We were able to rule out arsenic poisoning as the primary cause of death. High levels of gold and silver in both hair and liver samples were probably due to prolonged contact of the mummy with precious metals in the funeral garments. High lead concentrations in both liver and bone tissue can be traced back to the ingestion of contaminated food and alcoholic beverages. Most of the essential elements were in the normal range of values for contemporary living people. The low arsenic and chromium levels in the Prince's tissues as compared to modern people would be suggestive of raised concentrations of both the elements in the present era, which are likely due to industrial pollution.

  2. Rice early flowering1, a CKI, phosphorylates DELLA protein SLR1 to negatively regulate gibberellin signalling.

    PubMed

    Dai, Cheng; Xue, Hong-Wei

    2010-06-02

    The plant hormone gibberellin (GA) is crucial for multiple aspects of plant growth and development. To study the relevant regulatory mechanisms, we isolated a rice mutant earlier flowering1, el1, which is deficient in a casein kinase I that has critical roles in both plants and animals. el1 had an enhanced GA response, consistent with the suppression of EL1 expression by exogenous GA(3). Biochemical characterization showed that EL1 specifically phosphorylates the rice DELLA protein SLR1, proving a direct evidence for SLR1 phosphorylation. Overexpression of SLR1 in wild-type plants caused a severe dwarf phenotype, which was significantly suppressed by EL1 deficiency, indicating the negative effect of SLR1 on GA signalling requires the EL1 function. Further studies showed that the phosphorylation of SLR1 is important for maintaining its activity and stability, and mutation of the candidate phosphorylation site of SLR1 results in the altered GA signalling. This study shows EL1 a novel and key regulator of the GA response and provided important clues on casein kinase I activities in GA signalling and plant development.

  3. [Trattamento della dipendenza da alcol. Alcol e persone senza fissa dimora: punto di vista sociale].

    PubMed

    Alessandrini, Giovanni; Ciccarelli, Rosaria; Battagliese, Gemma; Cereatti, Federica; Gencarelli, Simona; Messina, Marisa Patrizia; Vitali, Mario; De Rosa, Francesca; Ledda, Roberta; Mancini, Serena; Attilia, Maria Luisa

    2018-01-01

    RIASSUNTO. Il fenomeno delle persone senza fissa dimora sta assumendo in questi anni una rilevanza sociale devastante, con una prevalenza stimata in USA e in Europa compresa tra il 5,6% e il 13,9%. Queste persone hanno una scarsa qualità di vita, una limitata o assente vita sociale, sono spesso disoccupate o lavorano solo saltuariamente. Sono a rischio di problemi con la legge, sono spesso affette da dipendenza da droghe, da patologie psichiatriche e internistiche. L'alcol spesso non rappresenta la causa della loro condizione sociale, ma solo la conseguenza, contribuendo in questo modo al loro degrado bio-psico-sociale. Nel 2009 lo US Department of Housing and Urban Development's Homelessness Assistance Programs e nel 2010 la European Consensus Conference on Homelessness hanno segnato un grande passo avanti nella riabilitazione sociale di queste persone, utilizzando il concetto del "case management". In particolare lo Standard Case Management si è dimostrato in grado di migliorare la stabilità abitativa, di ridurre l'uso di droghe e di rimuovere le barriere lavorative. L'Assertive Community Treatment si è dimostrato, invece, in grado di migliorare la stabilità abitativa e ha un rapporto costo/beneficio migliore per i pazienti affetti da doppia diagnosi.

  4. A case study of lean drug discovery: from project driven research to innovation studios and process factories.

    PubMed

    Ullman, Fredrik; Boutellier, Roman

    2008-06-01

    At the operational level, the number of investigational new drugs or candidates for development per dollar spent in research, and the number of patents per year are highly integrated measures of productivity and, thus, difficult to influence at the individual or lab level. Hence, different metrics are needed to assess and thereby improve productivity in research at the individual and group level. This review centers on a case study, including over 70 interviews, in a research department of a global pharmaceutical company as well as over 40 interviews in contract research organizations (CROs) and 5 in small biotechnology firms. For each lab, its value adding process was plotted according to lean six sigma methods and appropriate metrics were defined. We suggest a strong focus on short feedback loops in research as an indicator for efficiency. Our results reveal two categories of activities: creativity-driven ones and process-driven ones, both discussed with respect to the methodology used. The fundamental differences in nature of these activities require different sets of metrics to assess them. On the basis of these metrics, different organizational forms can be derived to achieve a lean research structure: innovation studios and process factories, respectively.

  5. Variable high-resolution color CCD camera system with online capability for professional photo studio application

    NASA Astrophysics Data System (ADS)

    Breitfelder, Stefan; Reichel, Frank R.; Gaertner, Ernst; Hacker, Erich J.; Cappellaro, Markus; Rudolf, Peter; Voelk, Ute

    1998-04-01

    Digital cameras are of increasing significance for professional applications in photo studios where fashion, portrait, product and catalog photographs or advertising photos of high quality have to be taken. The eyelike is a digital camera system which has been developed for such applications. It is capable of working online with high frame rates and images of full sensor size and it provides a resolution that can be varied between 2048 by 2048 and 6144 by 6144 pixel at a RGB color depth of 12 Bit per channel with an also variable exposure time of 1/60s to 1s. With an exposure time of 100 ms digitization takes approx. 2 seconds for an image of 2048 by 2048 pixels (12 Mbyte), 8 seconds for the image of 4096 by 4096 pixels (48 Mbyte) and 40 seconds for the image of 6144 by 6144 pixels (108 MByte). The eyelike can be used in various configurations. Used as a camera body most commercial lenses can be connected to the camera via existing lens adaptors. On the other hand the eyelike can be used as a back to most commercial 4' by 5' view cameras. This paper describes the eyelike camera concept with the essential system components. The article finishes with a description of the software, which is needed to bring the high quality of the camera to the user.

  6. A Rice gid1 Suppressor Mutant Reveals That Gibberellin Is Not Always Required for Interaction between Its Receptor, GID1, and DELLA Proteins[W][OA

    PubMed Central

    Yamamoto, Yuko; Hirai, Takaaki; Yamamoto, Eiji; Kawamura, Mayuko; Sato, Tomomi; Kitano, Hidemi; Matsuoka, Makoto; Ueguchi-Tanaka, Miyako

    2010-01-01

    To investigate gibberellin (GA) signaling using the rice (Oryza sativa) GA receptor GIBBERELLIN-INSENSITIVE DWARF1 (GID1) mutant gid1-8, we isolated a suppressor mutant, Suppressor of gid1-1 (Sgd-1). Sgd-1 is an intragenic mutant containing the original gid1-8 mutation (L45F) and an additional amino acid substitution (P99S) in the loop region. GID1P99S interacts with the rice DELLA protein SLENDER RICE1 (SLR1), even in the absence of GA. Substitution of the 99th Pro with other amino acids revealed that substitution with Ala (P99A) caused the highest level of GA-independent interaction. Physicochemical analysis using surface plasmon resonance revealed that GID1P99A has smaller Ka (association) and Kd (dissociation) values for GA4 than does wild-type GID1. This suggests that the GID1P99A lid is at least partially closed, resulting in both GA-independent and GA-hypersensitive interactions with SLR1. One of the three Arabidopsis thaliana GID1s, At GID1b, can also interact with DELLA proteins in the absence of GA, so we investigated whether GA-independent interaction of At GID1b depends on a mechanism similar to that of rice GID1P99A. Substitution of the loop region or a few amino acids of At GID1b with those of At GID1a diminished its GA-independent interaction with GAI while maintaining the GA-dependent interaction. Soybean (Glycine max) and Brassica napus also have GID1s similar to At GID1b, indicating that these unique GID1s occur in various dicots and may have important functions in these plants. PMID:21098733

  7. Comparative reproductive biology of the social parasite Acromyrmex ameliae de Souza, Soares & Della Lucia and of its host Acromyrmex subterraneus subterraneus Forel (Hymenoptera: Formicidae).

    PubMed

    Soares, Ilka M F; Della Lucia, Terezinha M C; Pereira, Alice S; Serrão, José E; Ribeiro, Myriam M R; De Souza, Danival J

    2010-01-01

    Social parasites exhibit several characteristics that allow them to exploit their host species efficiently. The smaller size of parasite species is a trait commonly found in ants. In this work, we investigated several aspects of the reproductive biology of Acromyrmex ameliae De Souza, Soares & Della Lucia, a recently discovered parasite of Acromyrmex subterraneus subterraneus Forel. Sexuals of A. ameliae are substantially smaller than those from host species. Parasite queens laid significantly less worker eggs than host queens and inhibit sexual production of the host. The sex ratio of parasite species is highly female biased. Interestingly, we have observed parasite coupling on the laboratory, inside the nests and in the ground, opening the possibility to use controlled mating to study genetic approaches of parasitism in the ants.

  8. Determination of Highly Sensitive Biological Cell Model Systems to Screen BPA-Related Health Hazards Using Pathway Studio.

    PubMed

    Ryu, Do-Yeal; Rahman, Md Saidur; Pang, Myung-Geol

    2017-09-06

    Bisphenol-A (BPA) is a ubiquitous endocrine-disrupting chemical. Recently, many issues have arisen surrounding the disease pathogenesis of BPA. Therefore, several studies have been conducted to investigate the proteomic biomarkers of BPA that are associated with disease processes. However, studies on identifying highly sensitive biological cell model systems in determining BPA health risk are lacking. Here, we determined suitable cell model systems and potential biomarkers for predicting BPA-mediated disease using the bioinformatics tool Pathway Studio. We compiled known BPA-mediated diseases in humans, which were categorized into five major types. Subsequently, we investigated the differentially expressed proteins following BPA exposure in several cell types, and analyzed the efficacy of altered proteins to investigate their associations with BPA-mediated diseases. Our results demonstrated that colon cancer cells (SW480), mammary gland, and Sertoli cells were highly sensitive biological model systems, because of the efficacy of predicting the majority of BPA-mediated diseases. We selected glucose-6-phosphate dehydrogenase (G6PD), cytochrome b-c1 complex subunit 1 (UQCRC1), and voltage-dependent anion-selective channel protein 2 (VDAC2) as highly sensitive biomarkers to predict BPA-mediated diseases. Furthermore, we summarized proteomic studies in spermatozoa following BPA exposure, which have recently been considered as another suitable cell type for predicting BPA-mediated diseases.

  9. Environmental and climatic conditions at a potential Glacial refugial site of tree species near the Southern Alpine glaciers. New insights from multiproxy sedimentary studies at Lago della Costa (Euganean Hills, Northeastern Italy)

    NASA Astrophysics Data System (ADS)

    Kaltenrieder, Petra; Belis, Claudio A.; Hofstetter, Simone; Ammann, Brigitta; Ravazzi, Cesare; Tinner, Willy

    2009-12-01

    It has been hypothesized that refugia of thermophilous tree species were located in Northern Italy very close to the Alps, though, this hypothesis has yet to be tested thoroughly. In contrast to Central and Southern Italy with its relative wealth of data, only a few fragmentary records are currently available from Northern Italy for the last Glacial (Würm, Weichselian). Our new study site Lago della Costa lies adjacent to the catchment of the megafans of the Alpine forelands and the braided rivers of the Northeastern Po Plain that have so far inhibited the recovery of continuous Glacial and Late-Glacial records. We analyze pollen, plant macrofossils, charcoal and ostracods to reconstruct the vegetation, fire and lake history for the period 33,000-16,000 cal. BP. We compare our data with Glacial records from Southern Europe to discuss similarities and dissimilarities between these potential refugial areas. A comparison with independent paleoclimatic proxies allows to assess potential linkages between environmental and climatic variability. New macrofossil and pollen data at Lago della Costa unambiguously document the local persistence of boreal tree taxa such as Larix decidua and Betula tree species around the study site during the last Glacial. The regular occurrence of pollen of temperate trees in the organic lake sediments (fine-detritus calcareous gyttja) suggests that temperate taxa such as Corylus avellana, Quercus deciduous, Tilia, Ulmus, Fraxinus excelsior, Carpinus, Abies alba and Fagus sylvatica, most likely survived the Last Glacial Maximum (LGM) at favorable sites in the Euganean Hills. The percentage values of temperate trees are comparable with those from Southern Europe (e.g. Monticchio in Southern Italy). We conclude that the Euganean Hills were one of the northernmost refugial areas of temperate taxa in Europe. However, the relative and absolute abundances of pollen of temperate trees are highly variable. Pollen-inferred declines of temperate tree

  10. Laser doppler and radar interferometer for contactless measurements on unaccessible tie-rods on monumental buildings: Santa Maria della Consolazione Temple in Todi

    NASA Astrophysics Data System (ADS)

    Gioffré, M.; Cavalagli, N.; Pepi, C.; Trequattrini, M.

    2017-01-01

    Non-contact measurements can be effectively used in civil engineering to assess the variation of structural performance with time. In the last decades this approach has received considerable interests from researchers working in the field of structural health monitoring (SHM). Indeed, non-contact measurements are very attractive because it is possible to perform non intrusive and non destructive investigations even being at a significant distance from the targets. Within this context, contactless measurements of the tie-rod vibrations in the Santa Maria della Consolazione Temple in Todi (Italy) are presented in this paper. In particular, laser vibrometer and radar interferometer measurements are used to estimate natural frequencies and mode shapes. This information is crucial to obtain the tensile axial force in the tie-rods, which can be used as an indicator of structural integrity or possible failure. Furthermore, a novel approach is proposed where drones (Unmanned Aerial Vehicles) can be successfully used to improve the effectiveness and the accuracy of the experimental activities.

  11. Determination of Highly Sensitive Biological Cell Model Systems to Screen BPA-Related Health Hazards Using Pathway Studio

    PubMed Central

    Ryu, Do-Yeal

    2017-01-01

    Bisphenol-A (BPA) is a ubiquitous endocrine-disrupting chemical. Recently, many issues have arisen surrounding the disease pathogenesis of BPA. Therefore, several studies have been conducted to investigate the proteomic biomarkers of BPA that are associated with disease processes. However, studies on identifying highly sensitive biological cell model systems in determining BPA health risk are lacking. Here, we determined suitable cell model systems and potential biomarkers for predicting BPA-mediated disease using the bioinformatics tool Pathway Studio. We compiled known BPA-mediated diseases in humans, which were categorized into five major types. Subsequently, we investigated the differentially expressed proteins following BPA exposure in several cell types, and analyzed the efficacy of altered proteins to investigate their associations with BPA-mediated diseases. Our results demonstrated that colon cancer cells (SW480), mammary gland, and Sertoli cells were highly sensitive biological model systems, because of the efficacy of predicting the majority of BPA-mediated diseases. We selected glucose-6-phosphate dehydrogenase (G6PD), cytochrome b-c1 complex subunit 1 (UQCRC1), and voltage-dependent anion-selective channel protein 2 (VDAC2) as highly sensitive biomarkers to predict BPA-mediated diseases. Furthermore, we summarized proteomic studies in spermatozoa following BPA exposure, which have recently been considered as another suitable cell type for predicting BPA-mediated diseases. PMID:28878155

  12. Artists Bob and Louise McCall in their studio in Paradise Valley, Arizona.

    NASA Image and Video Library

    2003-06-05

    Artists Bob and Louise McCall in their Paradise Valley, Arizona studio, in front of "Celebrating One Hundred Years of Powered Flight 1903-2003." The mural was created to celebrate the achievements of Wilbur and Orville Wright and to commemorate a century of powered flight. Many of the epic flights represented in the painting took place in the skies over NASA Dryden Flight Research Center. An equally important goal of this celebration is to encourage the values that have characterized 100 years of aviation history: ingenuity, inventiveness, persistence, creativity and courage. These values hold true not just for pioneers of flight, but also for all pioneers of invention and innovation, and they will remain an important part of America's future. "Celebrating One Hundred Years of Powered Flight, 1903-2003", documents many significant achievements in aeronautics and space flight from the dawn of powered flight to the present. Historic aircraft and spacecraft serve as the backdrop, highlighting six figures representing the human element that made these milestones possible. These figures stand, symbolically supported by the words of Wilbur Wright, "It is my belief that flight is possible…" The quote was taken from a letter written to his father on September 3rd, 1900, announcing Wilbur's intention to make "some experiments with a flying machine" at Kitty Hawk, North Carolina. "This year, Bob is helping us commemorate the Centennial of Flight with a beautiful mural slated for placement in our Dryden Flight Research Center that documents the history of flight from the Wright Flyer to the International Space Station. We should all take note, I think, that in the grand scheme of things, one hundred years is a very short period of time. In that blink of an eye we've gone from Kitty Hawk to Tranquility Base and now look forward to our rovers traversing the surface of Mars. Despite the challenges we face, the future we envision, like the future depicted in the artwork of Bo

  13. 76 FR 59890 - IFR Altitudes; Miscellaneous Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ... in Part *AWSON, GA FIX NELLO, GA FIX **7000 *5000--MRA **5500--MOCA Sec. 95.6006 VOR Federal Airway..., IN FIX *3500 *2400--MOCA BRYTO, IN FIX *PIONS, OH FIX **4000 *4000--MRA **2500--MOCA *PIONS, OH FIX WATERVILLE, OH VOR/DME.. **3300 *4000--MRA **2300--MOCA Sec. 95.6016 VOR Federal Airway V16 Is Amended to...

  14. Multi-Model Super-Ensemble Ocean Prediction: An Operational Example Using a Kalman Filter in the Adriatic Sea

    DTIC Science & Technology

    2007-04-01

    0602435N 6. AUTHOR(S) 5d. PROJECT NUMBER Michel Rixen, Jeffery W. Book, Paul J. Martin, Nadia Pinardi, Paolo Oddo, Jacopo Chiggiato , Nello Russo 5e. TASK...PREDICTION: AN OPERATIONAL EXAMPLE USING A KALMAN FILTER IN THE ADRIATIC SEA M. Rixen J, . Book 2, P. Martin 2, N. Pinardi 3, p. Oddo 3, j. Chiggiato ’, N

  15. Validation of the Simbionix PROcedure Rehearsal Studio sizing module: A comparison of software for endovascular aneurysm repair sizing and planning.

    PubMed

    Velu, Juliëtte F; Groot Jebbink, Erik; de Vries, Jean-Paul P M; Slump, Cornelis H; Geelkerken, Robert H

    2017-02-01

    An important determinant of successful endovascular aortic aneurysm repair is proper sizing of the dimensions of the aortic-iliac vessels. The goal of the present study was to determine the concurrent validity, a method for comparison of test scores, for EVAR sizing and planning of the recently introduced Simbionix PROcedure Rehearsal Studio (PRORS). Seven vascular specialists analyzed anonymized computed tomography angiography scans of 70 patients with an infrarenal aneurysm of the abdominal aorta, using three different sizing software packages Simbionix PRORS (Simbionix USA Corp., Cleveland, OH, USA), 3mensio (Pie Medical Imaging BV, Maastricht, The Netherlands), and TeraRecon (Aquarius, Foster City, CA, USA). The following measurements were included in the protocol: diameter 1 mm below the most distal main renal artery, diameter 15 mm below the lowest renal artery, maximum aneurysm diameter, and length from the most distal renal artery to the left iliac artery bifurcation. Averaged over the locations, the intraclass correlation coefficient is 0.83 for Simbionix versus 3mensio, 0.81 for Simbionix versus TeraRecon, and 0.86 for 3mensio versus TeraRecon. It can be concluded that the Simbionix sizing software is as precise as two other validated and commercially available software packages.

  16. The combination of digital surface scanners and cone beam computed tomography technology for guided implant surgery using 3Shape implant studio software: a case history report.

    PubMed

    Lanis, Alejandro; Álvarez Del Canto, Orlando

    2015-01-01

    The incorporation of virtual engineering into dentistry and the digitization of information are providing new perspectives and innovative alternatives for dental treatment modalities. The use of digital surface scanners with surgical planning software allows for the combination of the radiographic, prosthetic, surgical, and laboratory fields under a common virtual scenario, permitting complete digital treatment planning. In this article, the authors present a clinical case in which a guided implant surgery was performed based on a complete digital surgical plan combining the information from a cone beam computed tomography scan and the virtual simulation obtained from the 3Shape TRIOS intraoral surface scanner. The information was imported to and combined in the 3Shape Implant Studio software for guided implant surgery planning. A surgical guide was obtained by a 3D printer, and the surgical procedure was done using the Biohorizons Guided Surgery Kit and its protocol.

  17. A Comparison of Three-Dimensional Simulations of Traveling-Wave Tube Cold-Test Characteristics Using CST MICROWAVE STUDIO and MAFIA

    NASA Technical Reports Server (NTRS)

    Chevalier, C. T.; Herrmann, K. A.; Kory, C. L.; Wilson, J. D.; Cross, A. W.; Williams, W. D. (Technical Monitor)

    2001-01-01

    Previously, it was shown that MAFIA (solutions of Maxwell's equations by the Finite Integration Algorithm), a three-dimensional simulation code, can be used to produce accurate cold-test characteristics including frequency-phase dispersion, interaction impedance, and attenuation for traveling-wave tube (TWT) slow-wave structures. In an effort to improve user-friendliness and simulation time, a model was developed to compute the cold-test parameters using the electromagnetic field simulation software package CST MICROWAVE STUDIO (MWS). Cold-test parameters were calculated for several slow-wave circuits including a ferruled coupled-cavity, a folded waveguide, and a novel finned-ladder circuit using both MWS and MAFIA. Comparisons indicate that MWS provides more accurate cold-test data with significantly reduced simulation times. Both MAFIA and MWS are based on the finite integration (FI) method; however, MWS has several advantages over MAFIA. First, it has a Windows based interface for PC operation, making it very user-friendly, whereas MAFIA is UNIX based. MWS uses a new Perfect Boundary Approximation (PBA), which increases the accuracy of the simulations by avoiding stair step approximations associated with MAFIA's representation of structures. Finally, MWS includes a Visual Basic for Applications (VBA) compatible macro language that enables the simulation process to be automated and allows for the optimization of user-defined goal functions, such as interaction impedance.

  18. A New Approach to Teaching Petrology: Active Learning in a Studio Classroom

    NASA Astrophysics Data System (ADS)

    Perkins, D.

    2003-12-01

    During the past 15 years it has become clear that the traditional lecture and lab approach to college science teaching leaves much to be desired. The traditional approach is instructor oriented and based on passive learning. In contrast, current studies show that most students learn best when actively engaged in the learning process. Inquiry based learning and open ended projects have been shown to especially enhance learning by promoting higher order thinking. Recognizing the need for change, however, does not mean the changes are simple. The task of overhauling a course, replacing traditional approaches with more student oriented activities, requires a great deal of time and effort. It also involves much uncertainty and risk. At UND we have been experimenting with alternative pedagogies for a number of years. Change has been incremental, but this year we made wholesale changes in our petrology class. We converted it from the standard three lecture and one lab format to two 3-hour studio sessions per week. The distinction between lab and lecture is gone. In fact, there really are no lectures. The instructor talks for no more than 15 or 20 minutes at a time. Students spend most of their time doing, not listening. We emphasize collaborative active learning projects, some quite short and others lengthy and involved, and use a wide variety of activities. To assess the class, we have an outside consultant and we carry out weekly assessments to measure (1) how students are reacting to the various pedagogical approaches, and (2) how much student learning is actually occurring. This allows us to make adjustments and fine tune as necessary. We could not have made such changes a few years ago, simply because of the amount of work involved to create and test the necessary classroom materials. Today, however, there are many resources available to the reform minded teacher, and the resource base continues to grow. We borrowed heavily from other instructors at other

  19. Spectroscopic study of the degradation products in the holy water fonts in Santa Maria della Steccata Church in Parma (Italy).

    PubMed

    Bersani, D; Campani, E; Casoli, A; Lottici, P P; Marino, I-G

    2008-03-03

    Two holy water fonts (dated at the beginning of the XVII century) in the Santa Maria della Steccata Church in Parma (Italy) have recently been restored. Before the intervention, a detailed investigation on their degradation products was carried out to understand the mechanisms of alteration of the materials and to suggest appropriate restoration procedures. The analyses were performed by means of powder X-ray diffraction (XRD), micro-Fourier transform infrared (FTIR) and micro-Raman spectroscopies. Calcite, iron oxides, silicates and sodium chloride (from salted holy water) were found in the red coloured calcarenite. On and under the lead coverings, different lead oxides (mainly massicot), other lead salts (lead basic carbonate, cerussite, plumbonacrite Pb10O(OH)6(CO3)6 and lead-chlorine compounds as laurionite PbOHCl and phosgenite Pb2CO3Cl2) were identified by Raman spectroscopy and XRD. Haematite alpha-Fe2O3, goethite alpha-FeO(OH) and lepidocrocite gamma-FeO(OH) were found on and around the iron hinges. Lead compounds and sodium chloride, through crystallization and solubilization cycles, were responsible for the stone's degradation, whereas the iron corrosion materials on the hinges produced mechanical stress and cracks in the stone. Various suggestions have been given on how to restore these fonts and to remove the causes of damage.

  20. Geochemical and mineralogical fingerprints to distinguish the exploited ferruginous mineralisations of Grotta della Monaca (Calabria, Italy)

    NASA Astrophysics Data System (ADS)

    Dimuccio, Luca Antonio; Rodrigues, Nelson; Larocca, Felice; Pratas, João; Amado, Ana Margarida; de Carvalho, Luís A. E. Batista

    2017-02-01

    This study examines the geochemical and mineralogical variations in the ferruginous mineralisations that crop out within Grotta della Monaca, which is considered to be the most striking and best known example of a prehistoric iron mine-cave from the southern Apennines (Calabria, Italy). Previous archaeological research identified three local and distinct ancient exploitation phases of these ferruginous mineralisations: (1) an Upper Palaeolithic phase; (2) a Late Neolithic phase; and (3) a post-Medieval phase. These materials, which have various forms of complex mineralogical admixtures and range in colour from yellow-orange to red and darker brown shades, mainly consist of iron oxides/hydroxides (essentially goethite and lepidocrocite), which are often mixed with subordinate and variable amounts of other matrix components (carbonates, sulphates, arsenates, silicates and organic matter). Such ferruginous mineralisations generally correspond to geochemically heterogeneous massive dyke/vein/mammillary/stratiform facies that are exposed within the local caves along open fractures and inclined bedding planes and that partially cover cave wall niches/notches/pockets and ceiling cupolas/holes. Selected samples/sub-samples are analysed through a multi-technique approach with a handheld portable X-ray Fluorescence, X-ray Diffraction, micro-Raman and Fourier Transform Infrared spectroscope (both conventional and attenuated total reflection), which is combined with subsequent multivariate statistical analysis of the elemental concentration data. The geochemical and mineralogical results are used to individualise similar compositional clusters. As expected, the identified groups, each of which has very specific geochemical-mineralogical ;fingerprints; and spatial distributions, enable us to identify the sampled ferruginous mineralisations. These specific mineral resources can be compared to similar raw materials that are found in other neighbouring archaeological sites, with

  1. [Health expenditure for prevention in Italy (2006-2013): descriptive analysis, regional trends and international comparisons].

    PubMed

    Signorelli, Carlo; Odone, Anna; Bianco, Daniela; Di Vivo, Natalia; Bevere, Francesco

    2016-01-01

    Il dato dell'Organizzazione per la cooperazione e lo sviluppo economico (OCSE) del 2012, che indicava l'Italia come il Paese con la più bassa spesa in prevenzione sanitaria, ha dato lo spunto per una raccolta sistematica e un'analisi critica dei flussi disponibili sulla spesa per le attività di prevenzione in Italia. Le statistiche correnti di spesa sanitaria sono raccolte centralmente dall'Agenzia nazionale per i servizi sanitari regionali (Agenas) attraverso i modelli di rilevazione dei costi dei livelli essenziali di assistenza (LEA) delle aziende USL. Le tre macroaree dei LEA sono: assistenza distrettuale, assistenza ospedaliera e assistenza sanitaria collettiva in ambiente di vita e di lavoro. Le spese per la prevenzione rientrano in quest'ultima e sono ripartite nelle seguenti voci: attività di prevenzione rivolte alle persone, igiene degli alimenti e della nutrizione, igiene e sanità pubblica, prevenzione e sicurezza negli ambienti di lavoro, sanità pubblica veterinaria, attività medico-legale per finalità pubblica. Tra il 2006 e il 2013, ultimo dato disponibile, la spesa per le attività di prevenzione del Servizio sanitario nazionale (SSN) è rimasta costante in rapporto alla spesa sanitaria totale (4,2%), pari a 4,9 miliardi nel 2013. Nel periodo di studio considerato (2006-2013) appaiono in aumento le spese per le attività rivolte alle persone (+8,7%), attribuibili soprattutto a vaccinazioni e screening, e in diminuzione le attività di igiene pubblica (-5,7%) e quelle della sanità pubblica veterinaria (-3,8%). I confronti internazionali indicano una spesa per la prevenzione del 2,9% rispetto alla spesa sanitaria totale, costante negli anni e nella media dei Paesi OCSE. Per la prevenzione, l'Italia spende tanto quanto i Paesi che non possiedono un servizio sanitario pubblico; il dato risulta inferiore del 5% rispetto alla programmazione nazionale, con poche eccezioni e molta variabilità regionale all'interno delle componenti delle voci di spesa

  2. Geophysic data interperetation of Passo della Morte landslide: Eastern Italian Alps

    NASA Astrophysics Data System (ADS)

    Zoppe', G.; Costa, G.; Marcato, G.; Forte, E.

    2012-04-01

    The Passo della Morte block-slide covers a relative large area in the Carnic Alps, along the left side of the Tagliamento River, between Forni di Sotto and Ampezzo (N-E of Italy). The high seismicity and the presence of the landslide increase the risk associated to the interest area. Moreover the large volume of material involved in the landslide (a few million of cubic meters), the presence of important infrastructure such as the road and two tunnels which cross the landslide, as well as the presence of the Tagliamento River that flow at the foot of the landslide, make the area very vulnerable. This study concerns with the western part of the Deep Seated Gravitational Slope Deformation (DSGSD). It focuses on the potential instability of a rock slope (crossed by road tunnels) and its connection with the DSGSD activity. The main objectives of this study are: monitoring the rock mass movement, studying the seismic site effect and defining the stratigraphic and geological characteristics of involved materials. Two vibration sensors have been installed inside the potential landslide: a short-period seismometer and a piezoelectric transducer. The microseismic activity recorded by the sensors has been analyzed, with particular regard to periods characterized by rapid changes in recorded seismic signals, and then correlated with the precipitation trend to evaluate the existence of a possible correlation between these phenomena. The microseismic activity study has highlighted the existence of a close link between microseisms and acoustic emissions recorded respectively by the seismometer and by the piezoelectric transducer. In addition, the comparison with the rainfall pattern has shown a direct relationship between different rainfall events and the sharp increase of microseismic activity detected by the two instruments. The correlation is good, even if acoustic emissions appear to be more sensitive than microseisms to short duration and low intensity rainfall events. The

  3. Verification of operation of the actuator control system using the integration the B&R Automation Studio software with a virtual model of the actuator system

    NASA Astrophysics Data System (ADS)

    Herbuś, K.; Ociepka, P.

    2017-08-01

    In the work is analysed a sequential control system of a machine for separating and grouping work pieces for processing. Whereas, the area of the considered problem is related with verification of operation of an actuator system of an electro-pneumatic control system equipped with a PLC controller. Wherein to verification is subjected the way of operation of actuators in view of logic relationships assumed in the control system. The actuators of the considered control system were three drives of linear motion (pneumatic cylinders). And the logical structure of the system of operation of the control system is based on the signals flow graph. The tested logical structure of operation of the electro-pneumatic control system was implemented in the Automation Studio software of B&R company. This software is used to create programs for the PLC controllers. Next, in the FluidSIM software was created the model of the actuator system of the control system of a machine. To verify the created program for the PLC controller, simulating the operation of the created model, it was utilized the approach of integration these two programs using the tool for data exchange in the form of the OPC server.

  4. An analysis of the number of parking bays and checkout counters for a supermarket using SAS simulation studio

    NASA Astrophysics Data System (ADS)

    Kar, Leow Soo

    2014-07-01

    Two important factors that influence customer satisfaction in large supermarkets or hypermarkets are adequate parking facilities and short waiting times at the checkout counters. This paper describes the simulation analysis of a large supermarket to determine the optimal levels of these two factors. SAS Simulation Studio is used to model a large supermarket in a shopping mall with car park facility. In order to make the simulation model more realistic, a number of complexities are introduced into the model. For example, arrival patterns of customers vary with the time of the day (morning, afternoon and evening) and with the day of the week (weekdays or weekends), the transport mode of arriving customers (by car or other means), the mode of payment (cash or credit card), customer shopping pattern (leisurely, normal, exact) or choice of checkout counters (normal or express). In this study, we focus on 2 important components of the simulation model, namely the parking area, the normal and express checkout counters. The parking area is modeled using a Resource Pool block where one resource unit represents one parking bay. A customer arriving by car seizes a unit of the resource from the Pool block (parks car) and only releases it when he exits the system. Cars arriving when the Resource Pool is empty (no more parking bays) leave without entering the system. The normal and express checkouts are represented by Server blocks with appropriate service time distributions. As a case study, a supermarket in a shopping mall with a limited number of parking bays in Bangsar was chosen for this research. Empirical data on arrival patterns, arrival modes, payment modes, shopping patterns, service times of the checkout counters were collected and analyzed to validate the model. Sensitivity analysis was also performed with different simulation scenarios to identify the parameters for the optimal number the parking spaces and checkout counters.

  5. ScreenRecorder: A Utility for Creating Screenshot Video Using Only Original Equipment Manufacturer (OEM) Software on Microsoft Windows Systems

    DTIC Science & Technology

    2015-01-01

    class within Microsoft Visual Studio . 2 It has been tested on and is compatible with Microsoft Vista, 7, and 8 and Visual Studio Express 2008...the ScreenRecorder utility assumes a basic understanding of compiling and running C++ code within Microsoft Visual Studio . This report does not...of Microsoft Visual Studio , the ScreenRecorder utility was developed as a C++ class that can be compiled as a library (static or dynamic) to be

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    An OpenStudio Measure is a script that can manipulate an OpenStudio model and associated data to apply energy conservation measures (ECMs), run supplemental simulations, or visualize simulation results. The OpenStudio software development kit (SDK) and accessibility of the Ruby scripting language makes measure authorship accessible to both software developers and energy modelers. This paper discusses the life cycle of an OpenStudio Measure from development, testing, and distribution, to application.

  7. Bob Mccall and NASA Dryden Center Director Kevin Petersen in the artist's studio in Paradise Valley, Arizona.

    NASA Image and Video Library

    2003-06-05

    Bob Mccall and NASA Dryden Director Kevin Petersen stand by "Celebrating One Hundred Years of Powered Flight, 1903-2003", in the artist's studio in Paradise Valley, Arizona. The mural was created to celebrate the achievements of Wilbur and Orville Wright and to commemorate a century of powered flight. Many of the epic flights represented in the painting took place in the skies over NASA Dryden Flight Research Center. An equally important goal of this celebration will be to encourage the values that have characterized 100 years of aviation history: ingenuity, inventiveness, persistence, creativity and courage. These values hold true not just for pioneers of flight, but also for all pioneers of invention and innovation, and they will remain an important part of America's future. "Celebrating One Hundred Years of Powered Flight, 1903-2003", documents many significant achievements in aeronautics and space flight from the dawn of powered flight to the present. Historic aircraft and spacecraft serve as the backdrop, highlighting six figures representing the human element that made these milestones possible. These figures stand, symbolically supported by the words of Wilbur Wright, "It is my belief that flight is possible…" The quote was taken from a letter written to his father on September 3rd, 1900, announcing Wilbur's intention to make "some experiments with a flying machine" at Kitty Hawk, North Carolina. "This year, Bob is helping us commemorate the Centennial of Flight with a beautiful mural slated for placement in our Dryden Flight Research Center that documents the history of flight from the Wright Flyer to the International Space Station. We should all take note, I think, that in the grand scheme of things, one hundred years is a very short period of time. In that blink of an eye we've gone from Kitty Hawk to Tranquility Base and now look forward to our rovers traversing the surface of Mars. Despite the challenges we face, the future we envision, like the fu

  8. Bob McCall signs the Centennial of Flight mural in the artist's studio in Paradise Valley, Arizona.

    NASA Image and Video Library

    2003-06-05

    Artist Bob McCall signs the Centennial of Flight Mural in his Paradise Valley, Arizona Studio. The mural was created to celebrate the achievements of Wilbur and Orville Wright and to commemorate a century of powered flight. Many of the epic flights represented in the painting took place in the skies over NASA Dryden Flight Research Center. An equally important goal of this celebration is to encourage the values that have characterized 100 years of aviation history: ingenuity, inventiveness, persistence, creativity and courage. These values hold true not just for pioneers of flight, but also for all pioneers of invention and innovation, and they will remain an important part of America's future. "Celebrating One Hundred Years of Powered Flight, 1903-2003", documents many significant achievements in aeronautics and space flight from the dawn of powered flight to the present. Historic aircraft and spacecraft serve as the backdrop, highlighting six figures representing the human element that made these milestones possible. These figures stand, symbolically supported by the words of Wilbur Wright, "It is my belief that flight is possible…" The quote was taken from a letter written to his father on September 3rd, 1900, announcing Wilbur's intention to make "some experiments with a flying machine" at Kitty Hawk, North Carolina. "This year, Bob is helping us commemorate the Centennial of Flight with a beautiful mural slated for placement in our Dryden Flight Research Center that documents the history of flight from the Wright Flyer to the International Space Station. We should all take note, I think, that in the grand scheme of things, one hundred years is a very short period of time. In that blink of an eye we've gone from Kitty Hawk to Tranquility Base and now look forward to our rovers traversing the surface of Mars. Despite the challenges we face, the future we envision, like the future depicted in the artwork of Bob McCall, is a future of boundless possibility. "

  9. Symbiotic Fungi Control Plant Root Cortex Development through the Novel GRAS Transcription Factor MIG1.

    PubMed

    Heck, Carolin; Kuhn, Hannah; Heidt, Sven; Walter, Stefanie; Rieger, Nina; Requena, Natalia

    2016-10-24

    In an approaching scenario of soil nutrient depletion, root association with soil microorganisms can be key for plant health and sustainability [1-3]. Symbiotic arbuscular mycorrhizal (AM) fungi are major players in helping plants growing under nutrient starvation conditions. They provide plants with minerals like phosphate and, furthermore, act as modulators of plant growth altering the root developmental program [4, 5]. However, the precise mechanisms involved in this latter process are not well understood. Here, we show that AM fungi are able to modulate root cortex development in Medicago truncatula by activating a novel GRAS-domain transcription factor, MIG1, that determines the size of cortical root cells. MIG1 expression peaks in arbuscule-containing cells, suggesting a role in cell remodeling during fungal accommodation. Roots ectopically expressing MIG1 become thicker due to an increase in the number and width of cortical cells. This phenotype is fully counteracted by gibberellin (GA) and phenocopied with a GA biosynthesis inhibitor or by expression of a dominant DELLA (Δ18DELLA1) protein. MIG1 downregulation leads to malformed arbuscules, a phenotype rescued by Δ18DELLA1, suggesting that MIG1 intersects with the GA signaling to control cell morphogenesis through DELLA1. DELLA1 was shown to be a central node controlling arbuscule branching [6-8]. Now we provide evidence that, together with MIG1, DELLA1 is responsible for radial cortical cell expansion during arbuscule development. Our data point toward DELLA proteins being not only longitudinal root growth repressors [9] but also positive regulators of cortical radial cell expansion, extending the knowledge of how DELLAs control root growth. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. 47 CFR 73.3580 - Local public notice of filing of broadcast applications.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... construction of authorized facilities. (5) An authorization of facilities for remote pickup or studio links for... Communications Act (“* * * studios of foreign stations”) where the programs to be transmitted are special events... applicants for a permit pursuant to section 325(b) of the Communications Act (“* * * Studios of Foreign...

  11. 47 CFR 73.3580 - Local public notice of filing of broadcast applications.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... construction of authorized facilities. (5) An authorization of facilities for remote pickup or studio links for... Communications Act (“* * * studios of foreign stations”) where the programs to be transmitted are special events... applicants for a permit pursuant to section 325(b) of the Communications Act (“* * * Studios of Foreign...

  12. 47 CFR 73.3580 - Local public notice of filing of broadcast applications.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... construction of authorized facilities. (5) An authorization of facilities for remote pickup or studio links for... Communications Act (“* * * studios of foreign stations”) where the programs to be transmitted are special events... applicants for a permit pursuant to section 325(b) of the Communications Act (“* * * Studios of Foreign...

  13. Gibberellins Regulate Ovule Integument Development by Interfering with the Transcription Factor ATS1[OPEN

    PubMed Central

    Sacristan, Raquel

    2016-01-01

    Gibberellins (GAs) are plant hormones that regulate most plant life cycle aspects, including flowering and fruit development. Here, we demonstrate the implication of GAs in ovule development. DELLA proteins, negative GA response regulators, act as positive factors for ovule integument development in a mechanism that involves transcription factor ABERRANT TESTA SHAPE (ATS). The seeds of the della global mutant, a complete loss-of-function of DELLA, and the ats-1 mutant are remarkably similar, with a round shape, a disorganized testa, and viviparism. These defects are the result of an alteration in integuments that fail to fully develop and are shorter than in wild-type plants. ats-1 also shows some GA-related phenotypes, for example, higher germination rates and early flowering. In fact, ats-1 has elevated GA levels due to the activation of GA biosynthesis genes, which indicates that ATS inhibits GA biosynthesis. Moreover, DELLAs and ATS proteins interact, which suggests the formation of a transcriptional complex that regulates the expression of genes involved in integument growth. Therefore, the repression of GA biosynthesis by ATS would result in the stabilization of DELLAs to ensure correct ATS-DELLA complex formation. The requirement of both activities to coordinate proper ovule development strongly argues that the ATS-DELLA complex acts as a key molecular factor. This work provides the first evidence for a role of GAs in ovule and seed development. PMID:27794102

  14. [Analysis of factors predicting early unplanned readmissions].

    PubMed

    Di Domenico, Gabriella; Tersigni, Ivan; Federico, Bruno; Leuter, Cinzia

    2016-01-01

    OBIETTIVI: determinare i fattori associati ai ricoveri ripetuti per identificare i pazienti a rischio di riospedalizzazione entro i 30 giorni dalla dimissione. DISEGNO: analisi retrospettiva delle dimissioni nell'anno 2013 attraverso le schede di dimissione ospedaliera (SDO). 3.900 pazienti ricoverati presso il presidio ospedaliero "Fabrizio Spaziani" di Frosinone. PRINCIPALI MISURE DI OUTCOME: analisi bivariata per l'analisi dell'associazione tra variabili. La regressione logistica è stata utilizzata per identificare i fattori di rischio associati al ricovero ripetuto. RISULTATI: tra i 3.900 pazienti considerati, il 12,8% ha avuto una riammissione non programmata entro un mese dalla dimissione precedente per le stesse categorie diagnostiche principali (MCD). Sono state rilevate differenze statisticamente significative tra i pazienti con e senza ricovero ripetuto per età, durata della degenza, titolo di studio, condizione occupazionale e diagnosi. I fattori che aumentano la probabilità di una riospedalizzazione sono il vivere da solo, la condizione di pensionato o casalinga, una degenza più lunga e alcune diagnosi, fra cui malattie dell'apparato respiratorio, del sistema nervoso e dell'apparato urinario. CONCLUSIONE: alcune caratteristiche sociodemografiche e la diagnosi dei pazienti ospedalizzati sono associate al rischio di riospedalizzazione entro 30 giorni dalla dimissione. I dati disponibili nell'archivio delle SDO possono essere utilizzati per un'identificazione dei pazienti a rischio sui quali definire specifici piani di dimissione.

  15. Design Studio.

    ERIC Educational Resources Information Center

    Draze, Dianne; Palouda, Annelise

    This book presents information about 10 areas of design, with the main emphasis on graphic design. One section presents the creative problem solving process and provides practice in using this process to solve design problems. Students are given a glimpse of other areas of design, including fashion, industrial, architectural, decorative,…

  16. What We Talk About When We Talk About Art Therapy: An Outsider's Guide to Identity Crisis

    ERIC Educational Resources Information Center

    Lentz, Rob

    2008-01-01

    The author discusses Randy Vick's analysis of studio-based programs in the United States and Europe for artists with disabilities. The disability studio, advocates the writer, is generally a grassroots, ad-hoc creation, staffed by self-taught practitioners who operate seemingly unaware that the operation of studio programs for artists with…

  17. Gibberellin Perception by the Gibberellin Receptor and its Effector Recognition

    NASA Astrophysics Data System (ADS)

    Hakoshima, Toshio; Murase, Kohji; Hirano, Yoshinori; Sun, Tai-Ping

    Gibberellins control a diverse range of growth and developmental processes in higher plants and have been widely utilized in the agricultural industry. By binding to a nuclear receptor GIBBERELLIN INSENSITIVE DWARF1 (GID1), gibberellins regulate gene expression by promoting degradation of the transcriptional regulator DELLA proteins. The precise manner in which GID1 discriminates and becomes activated by bioactive gibberellins for specific binding to DELLA proteins remains unclear. We present the crystal structure of a ternary complex of Arabidopsis thaliana GID1A, a bioactive gibberellin and the N-terminal DELLA domain of GAI. In this complex, GID1a occludes gibberellin in a deep binding pocket covered by its N-terminal helical switch region, which in turn interacts with the DELLA domain containing DELLA, VHYNP and LExLE motifs. Our results establish a structural model of a plant hormone receptor which is distinct from the hormone-perception mechanism and effector recognition of the known auxin receptors.

  18. U.S. Leading from Behind in Libya? Thoughts for NATO before the Chicago Summit

    DTIC Science & Technology

    2012-04-25

    degli anni 1990, la linea di base della tecnologia e business divenne inglese. Paesi come la Francia abbandonarono la loro resistenza e ha ceduto...bene." 20 I social media su internet e il progresso della tecnologia smart phone ha dato vita a un linguaggio comune delle informazioni 24/7. Un...appello rivolto su NATO Review del Vice Segretario generale aggiunto per gli armamenti, e coordinatore della tecnologia per l‘antiterrorismo

  19. The Tempio della Consolazione in Todi: Integrated Geomatic Techniques for a Monument Description Including Structural Damage Evolution in Time

    NASA Astrophysics Data System (ADS)

    Radicioni, F.; Matracchi, P.; Brigante, R.; Brozzi, A.; Cecconi, M.; Stoppini, A.; Tosi, G.

    2017-05-01

    The Tempio della Consolazione in Todi (16th cent.) has always been one of the most significant symbols of the Umbrian landscape. Since the first times after its completion (1606) the structure has exhibited evidences of instability, due to foundation subsiding and/or seismic activity. Structural and geotechnical countermeasures have been undertaken on the Tempio and its surroundings from the 17th century until recent times. Until now a truly satisfactory analysis of the overall deformation and attitude of the building has not been performed, since the existing surveys record the overhangs of the pillars, the crack pattern or the subsidence over limited time spans. Describing the attitude of the whole church is in fact a complex operation due to the architectural character of the building, consisting of four apses (three polygonal and one semicircular) covered with half domes, which surround the central area with the large dome. The present research aims to fill the gap of knowledge with a global study based on geomatic techniques for an accurate 3D reconstruction of geometry and attitude, integrated with a historical research on damage and interventions and a geotechnical analysis. The geomatic survey results from the integration of different techniques: GPS-GNSS for global georeferencing, laser scanning and digital photogrammetry for an accurate 3D reconstruction, high precision total station and geometric leveling for a direct survey of deformations and cracks, and for the alignment of the laser scans. The above analysis allowed to assess the dynamics of the cracks occurred in the last 25 years by a comparison with a previous survey. From the photographic colour associated to the point cloud was also possible to map the damp patches showing on the domes intrados, mapping their evolution over the last years.

  20. Making Room for Group Work I: Teaching Engineering in a Modern Classroom Setting

    ERIC Educational Resources Information Center

    Wilkens, Robert J.; Ciric, Amy R.

    2005-01-01

    This paper describes the results of several teaching experiments in the teaching Studio of The University of Dayton's Learning-Teaching Center. The Studio is a state-of-the-art classroom with a flexible seating arrangements and movable whiteboards and corkboards for small group discussions. The Studio has a communications system with a TV/VCR…

  1. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Malczynski, Leonard A.

    This guide addresses software quality in the construction of Powersim{reg_sign} Studio 8 system dynamics simulation models. It is the result of almost ten years of experience with the Powersim suite of system dynamics modeling tools (Constructor and earlier Studio versions). It is a guide that proposes a common look and feel for the construction of Powersim Studio system dynamics models.

  2. Challenges and Opportunities for the Implementation of H-Bim with Regards to Historical Infrastructures: a Case Study of the Ponte Giorgini in Castiglione della Pescaia (grosseto - Italy)

    NASA Astrophysics Data System (ADS)

    Donato, V.; Biagini, C.; Bertini, G.; Marsugli, F.

    2017-05-01

    Historical Building Information Modeling (H-BIM) has been widely documented in literature and is becoming more popular with government bodies, who are increasingly choosing to make its use mandatory in public procurements and contracts. Although the system seems to be one of the best approaches for managing data and driving the decision-making process, several difficulties arise due to the amount of effort required in the initial phases, when the data derived from a geometrical survey must be converted into parametric elements. Moreover, users must decide on a "level of geometrical simplification" a long time in advance, and this inevitably leads to a loss of geometrical data. From this perspective, our research describes a procedure to optimize the workflow of information for existing artefacts, in order to achieve a "lean" H-BIM. In this article, we will analyse two aspects: the first relates to the level of accuracy in a digital model created from the two different point clouds achieved from laser scanner and form images, while the second concerns the conversion of this information into parametric elements (Building Object Models- BOMs) that need to have specific characteristics. The case study we are presenting is the "Ponte Giorgini" ("Giorgini Bridge") in Castiglione della Pescaia (Grosseto - Italy).

  3. Something Happens in Room 13: Bringing Truths into the World

    ERIC Educational Resources Information Center

    Grube, Vicky

    2015-01-01

    This qualitative study looks at how an art studio run by children in crisis impacts what we can learn about art and relationships. Room 13, an art studio on school grounds managed by children ages 7-11 years old, began in Scotland in the 1980's and is now worldwide. Room 13 young artists manage the studio, raise funds, and even hire an adult…

  4. High Frequency Magnetic Field Direction Finding Using MGL-S9A B-dot Sensors

    DTIC Science & Technology

    2013-03-21

    relationship for incident plane wave on a linear array . . . . . . . . . . . 26 3.1 B-dot sensor design in CST Microwave Studio...CST Microwave Studio with an infinite PEC ground plane. . . . . . . . . . . . . . . 50 4.2 Radiation pattern of a single B-dot sensor at 32 MHz...simulated in CST Microwave Studio with an infinite PEC ground plane. . . . . . . . . . . . . . . 50 4.3 Radiation efficiency of single loop versus B-dot

  5. "I CAMMINI DELLA REGINA" - Open Source based tools for preserving and culturally exploring historical traffic routes.

    NASA Astrophysics Data System (ADS)

    Cannata, Massimiliano; Colombo, Massimo; Antonovic, Milan; Cardoso, Mirko; Delucchi, Andrea; Gianocca, Giancarlo; Brovelli, Maria Antonia

    2015-04-01

    "I CAMMINI DELLA REGINA" (The Via Regina Paths) is an Interreg project funded within the transnational cooperation program between Italy and Switzerland 2007-2013. The aim of this project is the preservation and valorization of the cultural heritage linked to the walking historically paths crossing, connecting and serving the local territories. With the approach of leveraging the already existing tools, which generally consist of technical descriptions of the paths, the project uses the open source geospatial technologies to deploy innovative solutions which can fill some of the gaps in historical-cultural tourism offers. The Swiss part, and particularly the IST-SUPSI team, has been focusing its activities in the realization of two innovative solutions: a mobile application for the survey of historical paths and a storytelling system for immersive cultural exploration of the historical paths. The former, based on Android, allows to apply in a revised manner a consolidated and already successfully used methodology of survey focused on the conservation of the historical paths (Inventory of historical traffic routes in Switzerland). Up to now operators could rely only on hand work based on a combination of notes, pictures and GPS devices synthesized in manually drawn maps; this procedure is error prone and shows many problems both in data updating and extracting for elaborations. Thus it has been created an easy to use interface which allows to map, according to a newly developed spatially enabled data model, paths, morphological elements, and multimedia notes. When connected to the internet the application can send the data to a web service which, after applying linear referencing and further elaborating the data, makes them available using open standards. The storytelling system has been designed to provide users with cultural insights embedded in a multimedial and immersive geospatial portal. Whether the tourist is exploring physically or virtually the desired

  6. The Dynamics o f Institutional Reform in Contemporary Italian Politics.

    DTIC Science & Technology

    1992-12-01

    equilibrium," the Christian Democrats promised a "renewal" with top officials who could translate fresh ideas into effective 2 "L’Italia al voto della verita...34 Corriere della Sera, 5 April 1992, 1. ŗ "Forlani contro il Pri e le Leghe," Ii f, 30 March 1992, 3. 13 action, They even left open the possibility...drawn were mixed. They foreshadowed 9 Ibid. 10 Ibid. 11 "Sfiduciati, pero alle urne," Corriere della 5a, 25 March 1992, 4. 16 disaster for two members

  7. Translations on USSR Military Affairs, Number 1374

    DTIC Science & Technology

    1978-09-05

    film sequence, the viewer is supposed to note these mistakes and inform the studio how one should proceed correctly in the specific situation. ’This...enthusiastically to the quiz program. The studio received more than 5,000 letters. The panel of judges, headed by the chief of Lithuanian SSR Civil Defense...scripts or broadcast texts which are literally copied from instructions and textbooks. Rayon, city and enterprise radio studios do much to promote

  8. 11 CFR 104.20 - Reporting electioneering communications (2 U.S.C. 434(f)).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... broadcast, cable or satellite radio and television stations, studio time, material costs, and the charges... electioneering communications means the following: (i) Costs charged by a vendor, such as studio rental time...

  9. 11 CFR 104.20 - Reporting electioneering communications (2 U.S.C. 434(f)).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... broadcast, cable or satellite radio and television stations, studio time, material costs, and the charges... electioneering communications means the following: (i) Costs charged by a vendor, such as studio rental time...

  10. 11 CFR 104.20 - Reporting electioneering communications (2 U.S.C. 434(f)).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... broadcast, cable or satellite radio and television stations, studio time, material costs, and the charges... electioneering communications means the following: (i) Costs charged by a vendor, such as studio rental time...

  11. 11 CFR 104.20 - Reporting electioneering communications (2 U.S.C. 434(f)).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... broadcast, cable or satellite radio and television stations, studio time, material costs, and the charges... electioneering communications means the following: (i) Costs charged by a vendor, such as studio rental time...

  12. Transforming an Introductory Programming Course: From Lectures to Active Learning via Wireless Laptops

    NASA Astrophysics Data System (ADS)

    Barak, Miri; Harward, Judson; Kocur, George; Lerman, Steven

    2007-08-01

    Within the framework of MIT's course 1.00: Introduction to Computers and Engineering Problem Solving, this paper describes an innovative project entitled: Studio 1.00 that integrates lectures with in-class demonstrations, active learning sessions, and on-task feedback, through the use of wireless laptop computers. This paper also describes a related evaluation study that investigated the effectiveness of different instructional strategies, comparing traditional teaching with two models of the studio format. Students' learning outcomes, specifically, their final grades and conceptual understanding of computational methods and programming, were examined. Findings indicated that Studio-1.00, in both its extensive- and partial-active learning modes, enhanced students' learning outcomes in Java programming. Comparing to the traditional courses, more students in the studio courses received "A" as their final grade and less failed. Moreover, students who regularly attended the active learning sessions were able to conceptualize programming principles better than their peers. We have also found two weaknesses in the teaching format of Studio-1.00 that can guide future versions of the course.

  13. The 'Green Revolution' dwarfing genes play a role in disease resistance in Triticum aestivum and Hordeum vulgare.

    PubMed

    Saville, R J; Gosman, N; Burt, C J; Makepeace, J; Steed, A; Corbitt, M; Chandler, E; Brown, J K M; Boulton, M I; Nicholson, P

    2012-02-01

    The Green Revolution dwarfing genes, Rht-B1b and Rht-D1b, encode mutant forms of DELLA proteins and are present in most modern wheat varieties. DELLA proteins have been implicated in the response to biotic stress in the model plant, Arabidopsis thaliana. Using defined wheat Rht near-isogenic lines and barley Sln1 gain of function (GoF) and loss of function (LoF) lines, the role of DELLA in response to biotic stress was investigated in pathosystems representing contrasting trophic styles (biotrophic, hemibiotrophic, and necrotrophic). GoF mutant alleles in wheat and barley confer a resistance trade-off with increased susceptibility to biotrophic pathogens and increased resistance to necrotrophic pathogens whilst the converse was conferred by a LoF mutant allele. The polyploid nature of the wheat genome buffered the effect of single Rht GoF mutations relative to barley (diploid), particularly in respect of increased susceptibility to biotrophic pathogens. A role for DELLA in controlling cell death responses is proposed. Similar to Arabidopsis, a resistance trade-off to pathogens with contrasting pathogenic lifestyles has been identified in monocotyledonous cereal species. Appreciation of the pleiotropic role of DELLA in biotic stress responses in cereals has implications for plant breeding.

  14. The ‘Green Revolution’ dwarfing genes play a role in disease resistance in Triticum aestivum and Hordeum vulgare

    PubMed Central

    Saville, R. J.; Gosman, N.; Burt, C. J.; Makepeace, J.; Steed, A.; Corbitt, M.; Chandler, E.; Brown, J. K. M.; Boulton, M. I.; Nicholson, P.

    2012-01-01

    The Green Revolution dwarfing genes, Rht-B1b and Rht-D1b, encode mutant forms of DELLA proteins and are present in most modern wheat varieties. DELLA proteins have been implicated in the response to biotic stress in the model plant, Arabidopsis thaliana. Using defined wheat Rht near-isogenic lines and barley Sln1 gain of function (GoF) and loss of function (LoF) lines, the role of DELLA in response to biotic stress was investigated in pathosystems representing contrasting trophic styles (biotrophic, hemibiotrophic, and necrotrophic). GoF mutant alleles in wheat and barley confer a resistance trade-off with increased susceptibility to biotrophic pathogens and increased resistance to necrotrophic pathogens whilst the converse was conferred by a LoF mutant allele. The polyploid nature of the wheat genome buffered the effect of single Rht GoF mutations relative to barley (diploid), particularly in respect of increased susceptibility to biotrophic pathogens. A role for DELLA in controlling cell death responses is proposed. Similar to Arabidopsis, a resistance trade-off to pathogens with contrasting pathogenic lifestyles has been identified in monocotyledonous cereal species. Appreciation of the pleiotropic role of DELLA in biotic stress responses in cereals has implications for plant breeding. PMID:22090435

  15. Proceedings of the Ship Control Systems Symposium (9th) Held in Bethesda, Maryland on 10-14 September 1990. Theme: Automation in Surface Ship Control Systems, Today’s Applications and Future Trends. Volume 4

    DTIC Science & Technology

    1990-09-14

    and can be fused separately. The RTU’s low-power consumption makes them ideally suited for battery and solar powered applications. 3.5 Redundant...dei movimenti e delle sollecitazioni di una nave in mare tempestoso per mezzo del metodo dello spettro di energia e della teoria della

  16. Art therapy and mindfulness with survivors of political violence: A qualitative study.

    PubMed

    Kalmanowitz, Debra L; Ho, Rainbow T H

    2017-08-01

    This study's objective was to understand how art therapy and mindfulness meditation could be integrated together in the context of different cultures and political violence and in work with asylum seekers suffering from trauma. We conducted a qualitative phenomenological study based on the social construction paradigm. Twelve participants took part in 4 intensive full-day art therapy and mindfulness workshops. The study's setting was an art therapy and mindfulness studio ( Inhabited Studio ) in Hong Kong where participants engaged in art making and in mindfulness-meditation practice. Different aspects of the Inhabited Studio appealed to participants based on each individual's worldview, culture, religion, and coping style. Responses to the Inhabited Studio were organized into 7 thematic clusters. Five themes were categorized into 2 broad categories composed of personal elements (memory, identity) and mediating aspects (emotional/self-regulation, communication, and imagination). The final 2, resilience and worldview, spanned both areas. Participants found the Inhabited Studio culturally compatible and some of the skills they learned helpful in times of stress. This points to how this combination can contribute to building resilience. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  17. Offering the Moon to the Public

    NASA Astrophysics Data System (ADS)

    Papaioannou, K.; Chatzichristou, E.

    2017-09-01

    Il Mondo della Luna is a project that puts forward a series of activities with the aim to communicate and inspire young people and the public in general to explore space and planetary science through artistic actions. The focus of the action is F. J. Haydn's Opera "Il Mondo della Luna".

  18. Evaluation of HACCP Plans of Food Industries: Case Study Conducted by the Servizio di Igiene degli Alimenti e della Nutrizione (Food and Nutrition Health Service) of the Local Health Authority of Foggia, Italy

    PubMed Central

    Panunzio, Michele F.; Antoniciello, Antonietta; Pisano, Alessandra; Rosa, Giovanna

    2007-01-01

    With respect to food safety, many works have studied the effectiveness of self-monitoring plans of food companies, designed using the Hazard Analysis and Critical Control Point (HACCP) method. On the other hand, in-depth research has not been made concerning the adherence of the plans to HACCP standards. During our research, we evaluated 116 self-monitoring plans adopted by food companies located in the territory of the Local Health Authority (LHA) of Foggia, Italy. The general errors (terminology, philosophy and redundancy) and the specific errors (transversal plan, critical limits, hazard specificity, and lack of procedures) were standardized. Concerning the general errors, terminological errors pertain to half the plans examined, 47% include superfluous elements and 60% have repetitive subjects. With regards to the specific errors, 77% of the plans examined contained specific errors. The evaluation has pointed out the lack of comprehension of the HACCP system by the food companies and has allowed the Servizio di Igiene degli Alimenti e della Nutrizione (Food and Nutrition Health Service), in its capacity as a control body, to intervene with the companies in order to improve designing HACCP plans. PMID:17911662

  19. Integrated approach based on non-invasive investigations for the structural diagnosis of monuments: the case of the San Francesco della Scarpa Church in Lecce

    NASA Astrophysics Data System (ADS)

    Gizzi, Fabrizio; Leucci, Giovanni; Masini, Nicola; Persico, Raffaele; Quarta, Giovanni

    2015-04-01

    The paper shows the results of a diagnostics survey, based on the ground penetrating radar (GPR), seismic tomography and microtremor horizontal-to-vertical ratio (HVSR) method, to understand the causes of some static instability problems affecting the Church of San Francesco della Scarpa in Lecce (Apulia region, Southern Italy). The prospecting falls within the more general framework of a diagnostic investigation campaign for the restoration of the monument. This study case points out the great effectiveness of the employed diagnostic methods, when used in an integrated way, for detecting cracks and inhomogeneities in the inner structure of masonry building elements [1-2]. With regard to GPR prospecting, in order to better evidence the micro-fracture, a new algorithm, based on a clutter removal technique, has been used. In particular, it removes various unwanted signals such as cross talk, initial ground reflection and antenna ringing. Moreover, seismic tomographies provided complementary information on the mediocre state of conservation of some load bearing structures of the church. Finally, HVSR method allowed to study the relationship between decay patterns, instability problems and seismic response of the monument. Reference [1] Leucci G., Masini N., Persico R., Soldovieri F. 2011. GPR and sonic tomography for structural restoration: the case of the cathedral of Tricarico, Journal of Geophysics and Engineering, 8 (3), 76-92, doi:10.1088/1742-2132/8/3/S08. [2] Calia A., Leucci G., Masini N., Matera L., Persico R., Sileo M., 2012. Integrated prospecting in the Crypt of the Basilica of Saint Nicholas in Bari, Italy. Journal of Geophysics and Engineering, 9(3), 271-281, doi:10.1088/1742-2132/9/3/271.

  20. Calibrazioni a terra e prestazioni in volo di spettrometri ad immagine nel visibile e nel vicino infrarosso per l'esplorazione planetaria

    NASA Astrophysics Data System (ADS)

    Filacchione, Gianrico

    2006-10-01

    Nel corso dell’ultimo decennio l’esplorazione planetaria ha potuto beneficiare dei dati prodotti dagli spettrometri ad immagine: grazie a questa nuova classe di strumenti, realizzati per l’osservazione in remoto di superfici ed atmosfere planetarie, è possibile acquisire dati iperspettrali con elevati poteri risolutivi spaziali e spettrali. Il principale vantaggio offerto dagli spettrometri ad immagine, rispetto alle camere ed agli spettrometri puntuali, è rappresentato dalla capacità di misurare, identificare e mappare le unità composizionali delle superfici planetarie; queste informazioni permettono di investigare sia l’evoluzione geochimica delle superfici sia la dinamica e la composizione delle atmosfere. Sebbene i primi spettrometri ad immagine siano stati francesi (Phobos/ISM, Imaging Spectrometer for Mars) e statunitensi (Galileo/NIMS, Near Infrared Mapping Spectrometer), il nostro paese nel corso degli ultimi anni è stato in grado di proporre alla com unità spaziale internazionale degli strumenti dalle elevate prestazioni che sono stati infatti accettati come payload scientifici su diverse missioni interplanetarie: dai canali visibili di VIMS (Visual and Infrared Mapping Spectrometer) su Cassini (Nasa, JPL, ESA, ASI) e di OMEGA (Observatoire pour la Minéralogie, l’Eau, les Glacies et l’Activitè de Mars) su MarsExpress (ESA) ai due VIRTIS (Visible and Infrared Thermal Imaging Spectrometer) su Rosetta (ESA) e VenusExpress (ESA) fino a VIR-MS (Visible and Infrared Mapping Spectrometer) su Dawn (Nasa). In questo momento inoltre altri due spettrometri sono in avanzata fase di studio: JIRAM (Jovian InfraRed Auroral Mapper) su Juno (missione New Discovery Nasa) e VIHI (Visible and Infrared Hyperspectral Imager) integrato nel payload italiano di remote sensing SIMBIO-SYS di BepiColombo (missione cornerstone ESA). La realizzazione di uno spettrometro ad immagini da utilizzare su una missione interplanetaria richiede un’accurata analisi in fase

  1. 75 FR 57825 - Culturally Significant Objects Imported for Exhibition Determinations: “Ancient Chinese Bronzes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... DEPARTMENT OF STATE [Public Notice 7181] Culturally Significant Objects Imported for Exhibition Determinations: ``Ancient Chinese Bronzes From the Shouyang Studio: The Katherine and George Fan Collection... ``Ancient Chinese Bronzes from the Shouyang Studio: The Katherine and George Fan Collection,'' imported from...

  2. Hypogenic contribution to speleogenesis in a predominant epigenic karst system: A case study from the Venetian Alps, Italy

    NASA Astrophysics Data System (ADS)

    Tisato, Nicola; Sauro, Francesco; Bernasconi, Stefano M.; Bruijn, Rolf H. C.; De Waele, Jo

    2012-05-01

    Buso della Rana and Buso della Pisatela are two karstic caves located in north-east Italy. They are part of the same karst system and are developed in the Castelgomberto calcarenitic marine sediments, which were deposited in a shallow Caribbean-type sea during the Eocene. The Buso della Rana-Pisatela system developed mostly at the contact between the Castelgomberto calcarenite and underlying volcanic rocks. The system of caves is ~ 37 km long and has only three entrances, two of which are semi-artificial. The overlying karst plateau is not directly connected to the Buso della Rana-Pisatela system and, with the exception of one deep abyss, exhibits a rather poorly developed karst. This is unexpected considering the presence at depth of such a large and long cave. Gypsum (CaSO4·2H2O) has locally been observed on the walls of the Buso della Pisatela cave. Energy dispersive X-ray spectroscopy (EDS), performed with a scanning electron microscope (SEM), reveals the presence of sulfur-bearing minerals within the host rock. Gypsum was formed by oxidation of these minerals as indicated by negative δ34S values. The oxidation of sulfide minerals forms a sulfuric-acid solution that dissolves the Castelgomberto calcarenite and, once it is oversaturated in calcium, precipitates as gypsum. The lack of well-developed karst on top of the plateau and the analyses suggest that the formation mechanisms for the Buso della Rana-Pisatela system differ from classical epigenic speleogenesis. The "pyrite-effect" has been recognized in other caves and described in literature. In our case pyrite is responsible of two hypo-speleogenetic processes: i) the dissolution of a portion of the host rock and ii) the enlargement of the karst voids as a consequence of the haloclastic effect.

  3. Evaluation of the 'Ladder to the Moon, Culture Change Studio Engagement Programme' staff training: Two quasi-experimental case studies.

    PubMed

    Guzmán, Azucena; Wenborn, Jennifer; Swinson, Tom; Orrell, Martin

    2017-09-01

    To evaluate the impact of the CCSEP on care home staff in two care settings for older people in one nursing home and one residential home. Care homes provide personal care and accommodation for older people. The English Dementia Strategy aims to improve the quality of service provision for people with dementia. This includes specific mention of improving the quality of life in care homes and as such includes objectives related to developing the workforce knowledge and skills. The Ladder to the Moon Culture Change Studio Engagement Programme (CCSEP) is a staff training approach based on the Positive Psychology framework that uses theatre- and film-based activities. This study used a wait-list controlled design. However, the data analysis plan was amended to reflect difficulties in data collection, and a quasi-experimental case study approach was consequently utilised. Outcome measures for staff attitudes and beliefs were as follows: Sense of Competence in Dementia Care Staff; Approaches to Dementia Questionnaire; Job Satisfaction Index; Brief Learning Transfer System Inventory; and Scale of Positive and Negative Experience. The Quality of Interaction Schedule (QUIS) was used to observe changes in staff-resident interaction. Fifty staff in two care homes completed the questionnaires and forty-one undertook formal CCSEP training. In Home A (nursing home), there was no significant change in any of the measures. In Home B (residential home), the QUIS showed an increase in positive interactions post intervention; a significant increase in the Building Relationship subscale of Sense of Competence; and a significant increase in staff sense of hopefulness towards people with dementia. The Brief Learning Transfer System Inventory showed a significant decrease post-intervention. The intervention did not significantly affect the happiness or job satisfaction of care home staff. The results of this study provide tentative evidence about the efficacy of this staff training

  4. Growth and Yield of Thinned Yellow-Poplar

    Treesearch

    Donald E. Beck; Lino Della-Bianca

    1972-01-01

    Diameter distributions and yields for various combinations of site index, age, and density for unthinned and largely undisturbed stands of yellow-poplar (Liriodendron tulipifera L. ) have been presented by McGee and Della-Bianca (1967) and Beck and Della-Bianca (1970). Their results were based on the initial measurements of a network of permanent sample plots...

  5. Plant hormone jasmonate prioritizes defense over growth by interfering with gibberellin signaling cascade.

    PubMed

    Yang, Dong-Lei; Yao, Jian; Mei, Chuan-Sheng; Tong, Xiao-Hong; Zeng, Long-Jun; Li, Qun; Xiao, Lang-Tao; Sun, Tai-ping; Li, Jigang; Deng, Xing-Wang; Lee, Chin Mei; Thomashow, Michael F; Yang, Yinong; He, Zuhua; He, Sheng Yang

    2012-05-08

    Plants must effectively defend against biotic and abiotic stresses to survive in nature. However, this defense is costly and is often accompanied by significant growth inhibition. How plants coordinate the fluctuating growth-defense dynamics is not well understood and remains a fundamental question. Jasmonate (JA) and gibberellic acid (GA) are important plant hormones that mediate defense and growth, respectively. Binding of bioactive JA or GA ligands to cognate receptors leads to proteasome-dependent degradation of specific transcriptional repressors (the JAZ or DELLA family of proteins), which, at the resting state, represses cognate transcription factors involved in defense (e.g., MYCs) or growth [e.g. phytochrome interacting factors (PIFs)]. In this study, we found that the coi1 JA receptor mutants of rice (a domesticated monocot crop) and Arabidopsis (a model dicot plant) both exhibit hallmark phenotypes of GA-hypersensitive mutants. JA delays GA-mediated DELLA protein degradation, and the della mutant is less sensitive to JA for growth inhibition. Overexpression of a selected group of JAZ repressors in Arabidopsis plants partially phenocopies GA-associated phenotypes of the coi1 mutant, and JAZ9 inhibits RGA (a DELLA protein) interaction with transcription factor PIF3. Importantly, the pif quadruple (pifq) mutant no longer responds to JA-induced growth inhibition, and overexpression of PIF3 could partially overcome JA-induced growth inhibition. Thus, a molecular cascade involving the COI1-JAZ-DELLA-PIF signaling module, by which angiosperm plants prioritize JA-mediated defense over growth, has been elucidated.

  6. JPRS Report, Soviet Union, EKO: Economics & Organization of Industrial Production, No. 11, November 1987.

    DTIC Science & Technology

    1988-03-22

    Orlov, doctor of economic sciences, Institute of Economics and Organization of Industrial Production of the Siberian Branch of the USSR Acad- emy...mined not by his talent, but by the studio in which he works: the larger the studio the greater the possibilities. Justice demands that everyone

  7. Career Field Experience: A Look at On-site Usage by High School Communication Class.

    ERIC Educational Resources Information Center

    Kaye, Thomas

    The career field experience program at a midwestern high school places broadcasting students on location for observation of the profession and optional job training or work. In addition to radio and television stations, field locations include advertising agencies with production studios, corporate production facilities, recording studios, cable…

  8. Sortings, Cutaways, and Bindings: Quilt-Making as Arts-Based Practice for Social Justice Teaching

    ERIC Educational Resources Information Center

    Kuthy, Diane; Broadwater, Kay

    2014-01-01

    This article describes a studio assignment grounded in social learning theory and intersectionality completed by preservice teachers during their first art education class, enabling students to begin to develop nuanced understandings about categories of difference. A studio assignment combines experiences in museum, community, and school settings…

  9. EarthShapes: Potential for Place-Based Teacher Learning between the Virtual and the Actual

    ERIC Educational Resources Information Center

    Triggs, Valerie

    2009-01-01

    This contribution investigates a recent research project involving in-service teacher learning as experienced through an online/offline art studio in which common experiences of relationships to particular local landforms generate imaginative and collaborative processes and practices of teaching and learning. EarthShapes Studio is both a…

  10. Strategies for Successfully Teaching Students with ADD or ADHD in Instrumental Lessons

    ERIC Educational Resources Information Center

    Melago, Kathleen A.

    2014-01-01

    Teachers can easily encounter students with Attention Deficit Disorder (ADD) or Attention Deficit Hyperactivity Disorder (ADHD) in the instrumental lesson setting. Applicable to instrumental lesson settings in the public or private schools, private studios, or college studios, this article focuses on specific strategies ranging from the…

  11. TA Beliefs in a SCALE-UP Style Classroom

    NASA Astrophysics Data System (ADS)

    DeBeck, George; Settelmeyer, Sam; Li, Sissi; Demaree, Dedra

    2010-10-01

    In Spring 2010, the Oregon State University physics department instituted a SCALE-UP (Student-Centered Active Learning Environment for Undergraduate Programs) style studio classroom in the introductory, calculus-based physics series. In our initial implementation, comprised of two hours lecture, two hours of studio, and two hours lab work, the studio session was lead by a faculty member and either 2 GTAs or 1 GTA and 1 LA. We plan to move to a model where senior GTAs can lead studio sections after co-teaching with the faculty member. It is critical that we know how to prepare and support the instructional team in facilitating student learning in this setting. We examine GTA and LA pedagogical beliefs through reflective journaling, interviews, and personal experience of the authors. In particular, we examine how these beliefs changed over their first quarter of instruction, as well as the resources used to adapt to the new classroom environment.

  12. Breaking Down Walls to Creativity through Interdisciplinary Design

    ERIC Educational Resources Information Center

    West, Richard E.

    2016-01-01

    This article describes initial success in developing an interdisciplinary studio for teaching collaborative creativity and design, with faculty from multiple departments co-teaching and co-mentoring interdisciplinary student groups engaged in social innovation. The rationale for developing this studio has been to prepare students for the kind of…

  13. Study of the Dynamics of a Pressurized Reactor as Integral Unit for Naval Propulsion; STUDIO DELLA DINAMICA DI UN REATTORE PRESSURIZZATO AD UNITA INTEGRALE PER PROPULSIONE NAVALE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gilardi, E.; Cimorelli, L.

    1963-07-01

    The dynamic behavior of an integrated, pressurizedwater reactor with natural circulation was investigated both by analog computer techniques and a simplified analytical approach. Hydraulic instabilities due to the core or riser were considered, as well as overall stability and problems arising from heavy sea conditions. (auth)

  14. NREL's Impact Grows Through the Clean Energy Solutions Center and the New

    Science.gov Websites

    Clean Energy Design Studio - Continuum Magazine | NREL NREL's Impact Grows Through the Clean Energy Solutions Center and the New Clean Energy Design Studio The Clean Energy Solutions Center (Solutions Center) helps governments design and adopt policies and programs that support the deployment of

  15. Dramatic Arts Facilities.

    ERIC Educational Resources Information Center

    Ontario Dept. of Education, Toronto. School Planning and Building Research Section.

    This booklet begins by explaining the function, the common planning errors, some location specifications, and the general requirements for any dramatic arts area. Facilities for (1) a single classroom, (2) a double classroom, (3) a specifically designed studio, and (4) a specifically designed studio complex are then described and illustrated.…

  16. Preventing or Inventing? Understanding the Effects of Non-Prescriptive Design Briefs

    ERIC Educational Resources Information Center

    Oliveira, Sonja; Marco, Elena

    2017-01-01

    This paper discusses observations of an architecture and environmental engineering undergraduate design studio project assigned to 4th year students at a UK university. In the UK, most architecture courses are characterised by a high proportion of design studio teaching supported by varying amount of technical modules that include environmental…

  17. Benefits of a STEAM Collaboration in Newark, New Jersey: Volcano Simulation through a Glass-Making Experience

    ERIC Educational Resources Information Center

    Gates, Alexander E.

    2017-01-01

    A simulated physical model of volcanic processes using a glass art studio greatly enhanced enthusiasm and learning among urban, middle- to high-school aged, largely underrepresented minority students in Newark, New Jersey. The collaboration of a geoscience department with a glass art studio to create a science, technology, engineering, arts, and…

  18. Fragmentation and Interrogation as an Approach to Integration

    ERIC Educational Resources Information Center

    Wallick, Karl; Zaretsky, Michael

    2010-01-01

    This article tracks the generative role of research and fragmentation as a means for integrating technology and form within an architecture technology lecture class and a co-requisite design studio. The complexity of teaching building systems integration within a design studio context is achieved by removing any expectation of building design…

  19. The non-gibberellic acid-responsive semi-dwarfing gene uzu affects Fusarium crown rot resistance in barley.

    PubMed

    Chen, Guangdeng; Yan, Wei; Liu, Yaxi; Wei, Yuming; Zhou, Meixue; Zheng, You-Liang; Manners, John M; Liu, Chunji

    2014-01-13

    Studies in Arabidopsis show that DELLA genes may differentially affect responses to biotrophic and necrophic pathogens. A recent report based on the study of DELLA-producing reduced height (Rht) genes in wheat and barley also hypothesized that DELLA genes likely increased susceptibility to necrotrophs but increased resistance to biotrophs. Effects of uzu, a non-GA (gibberellic acid)-responsive semi-dwarfing gene, on Fusarium crown rot (FCR) resistance in barley were investigated. Fifteen pairs of near isogenic lines for this gene were generated and assessed under two different temperature regimes. Similar to its impacts on plant height, the semi-dwarfing gene uzu also showed larger effects on FCR severity in the high temperature regime when compared with that in the low temperature regime. Results from this study add to the growing evidence showing that the effects of plant height on Fusarium resistances are unlikely related to DELLA genes but due to direct or indirect effects of height difference per se. The interaction between these two characteristics highlights the importance of understanding relationships between resistance and other traits of agronomic importance as the value of a resistance gene could be compromised if it dramatically affects plant development and morphology.

  20. Seeking and Collecting at Home: Sharing Personal Histories in the Art Room

    ERIC Educational Resources Information Center

    Bey, Sharif

    2012-01-01

    Collecting and placing images/objects of inspiration and personal significance is not an uncommon practice for studio artists. Washington based mixed-media/installation artist Renee Stout draws from the collections she displays in her studio and in her home. She is an avid collector of various objects, including vintage perfumes, West African…

  1. Room 13: The Movement and International Network

    ERIC Educational Resources Information Center

    Gibb, Claire

    2012-01-01

    Room 13 is a global uprising of creative and entrepreneurial children who are responsible for a growing international network of student-organised art studios. Each Room 13 studio facilitates the work of young artists alongside a professional adult artist in residence, providing an exchange of ideas, skills and experience across the ages. The…

  2. Mozart to Michelangelo: Software to Hone Your Students' Fine Arts Skills.

    ERIC Educational Resources Information Center

    Smith, Russell

    2000-01-01

    Describes 15 art and music computer software products for classroom use. "Best bets" (mostly secondary level) include Clearvue Inc.'s Art of Seeing, Sunburst Technology's Curious George Paint & Print Studio, Inspiration Software's Inspiration 6.0, Harmonic Vision's Music Ace 2, and Coda Music Technology's PrintMusic! 2000 and SmartMusic Studio.…

  3. Teaching and Learning How to Create in Schools of Art and Design

    ERIC Educational Resources Information Center

    Sawyer, R. Keith

    2018-01-01

    This article describes the "studio model"--a cultural model of teaching and learning found in U.S. professional schools of art and design. The studio model includes the pedagogical beliefs held by professors and the pedagogical practices they use to guide students in learning how to create. This cultural model emerged from an…

  4. Perfect Lighting for Facial Photography in Aesthetic Surgery: Ring Light.

    PubMed

    Dölen, Utku Can; Çınar, Selçuk

    2016-04-01

    Photography is indispensable for plastic surgery. On-camera flashes can result in bleached out detail and colour. This is why most of the plastic surgery clinics prefer studio lighting similar to professional photographers'. In this article, we want to share a simple alternative to studio lighting that does not need extra space: Ring light. We took five different photographs of the same person with five different camera and lighting settings: Smartphone and ring light; point and shoot camera and on-camera flash; point and shoot camera and studio lighting; digital single-lens reflex (DLSR) camera and studio lighting; DSLR and ring light. Then, those photographs were assessed objectively with an online survey of five questions answered by three distinct populations: plastic surgeons (n: 28), professional portrait photographers (n: 24) and patients (n: 22) who had facial aesthetic procedures. Compared to the on-camera flash, studio lighting better showed the wrinkles of the subject. The ring light facilitated the perception of the wrinkles by providing homogenous soft light in a circular shape rather than bursting flashes. The combination of a DSLR camera and ring light gave the oldest looking subject according to 64 % of responders. The DSLR camera and the studio lighting demonstrated the youngest looking subject according to 70 % of the responders. The majority of the responders (78 %) chose the combination of DSLR camera and ring light that exhibited the wrinkles the most. We suggest using a ring light to obtain well-lit photographs without loss of detail, with any type of cameras. However, smartphones must be avoided if standard pictures are desired. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

  5. A Model for Managing 3D Printing Services in Academic Libraries

    ERIC Educational Resources Information Center

    Scalfani, Vincent F.; Sahib, Josh

    2013-01-01

    The appearance of 3D printers in university libraries opens many opportunities for advancing outreach, teaching, and research programs. The University of Alabama (UA) Libraries recently adopted 3D printing technology and maintains an open access 3D Printing Studio. The Studio consists of a 3D printer, multiple 3D design workstations, and other…

  6. Some Psychoanalytic Observations on Quiet, Ordinary and Painful Resistance

    ERIC Educational Resources Information Center

    Britzman, Deborah P.

    2010-01-01

    The psychoanalyst is a student in the overabundant studio of resistance. This article inquires into such an affected learning position in educational contexts to ask what resistance to learning holds in store. What can it mean for the educator to assume the position of student in the overabundant studio of resistance and involve learning with…

  7. The Practice of an Artist Who Is Also an Arts Worker

    ERIC Educational Resources Information Center

    Ambrose-Smith, Neal; Smith, Janue Quick-to-See

    2014-01-01

    This Instructional Resource relates the experiences of Native American artist Neal Ambrose-Smith, who views himself not only as an artist with a studio practice, but also as an "Arts Worker" who pursues learning new knowledge with his arts-related jobs. Painting, sculpting, and printmaking are only three areas of his studio practice. He…

  8. Building 21: B21 Philadelphia

    ERIC Educational Resources Information Center

    EDUCAUSE, 2015

    2015-01-01

    As a non-selective neighborhood high school in the School District of Philadelphia, B21's mission is to empower networks of learners to connect with their passions and build agency to impact their world. Building 21 is organized into studios, workshops, and advisories. Core studios engage students in project-based learning. Blended learning…

  9. Fictions of the Studio

    ERIC Educational Resources Information Center

    Belshaw, Michael

    2011-01-01

    Not so long ago the occasional story would be told in the news that someone with a fascination for all things medical had spent months or even years masquerading as a doctor in a large and anonymous hospital. No doubt the absence of such stories today is due to heightened security and vigilance, partly as a result of the realization among hospital…

  10. Reviews Book: Enjoyable Physics Equipment: SEP Colorimeter Box Book: Pursuing Power and Light Equipment: SEP Bottle Rocket Launcher Equipment: Sciencescope GLE Datalogger Equipment: EDU Logger Book: Physics of Sailing Book: The Lightness of Being Software: Logotron Insight iLog Studio iPhone Apps Lecture: 2010 IOP Schools and Colleges Lecture Web Watch

    NASA Astrophysics Data System (ADS)

    2010-09-01

    WE RECOMMEND Enjoyable Physics Mechanics book makes learning more fun SEP Colorimeter Box A useful and inexpensive colorimeter for the classroom Pursuing Power and Light Account of the development of science in the 19th centuary SEP Bottle Rocket Launcher An excellent resource for teaching about projectiles GLE Datalogger GPS software is combined with a datalogger EDU Logger Remote datalogger has greater sensing abilities Logotron Insight iLog Studio Software enables datlogging, data analysis and modelling iPhone Apps Mobile phone games aid study of gravity WORTH A LOOK Physics of Sailing Book journeys through the importance of physics in sailing The Lightness of Being Study of what the world is made from LECTURE The 2010 IOP Schools and Colleges Lecture presents the physics of fusion WEB WATCH Planet Scicast pushes boundaries of pupil creativity

  11. The Tatmadaw and Human Rights: Changing a Military Mindset

    DTIC Science & Technology

    2014-10-30

    2012): 1 , accessed September 3 , 2014, EBSCOhost. 4Ibid., 1 . 5 Ibid. 6 Jim Della-Giacoma and Richard Horsey, “House Divided: Finding Peace in...Multiethnic Myanmar," World Politics Review : 1 . accessed September 3 , 2014, EBSCOhost. 7 Christopher O’Hara and Neil Selling, “Myanmar’s Ethnic...Counter Terrorism Reference Center (June 2012): 1 -12. accessed September 3 , 2014, EBSCOhost. Della-Giacoma, Jim and Horsey, Richard, “House Divided

  12. Hope as a Political Category

    ERIC Educational Resources Information Center

    Kentridge, William

    2016-01-01

    This is a lightly edited text of an address given to the graduating class of the University of Cape Town in December 2014. The author points out that the studio has made him. It is, however, "a place where the world is taken apart and re-arranged" and "where peripheral thinking is demanded". Like the studio, contemporary South…

  13. The Tomato (Solanum Lycopersicum cv. Micro-Tom) Natural Genetic Variation Rg1 and the DELLA Mutant Procera Control the Competence Necessary to Form Adventitious Roots and Shoots

    PubMed Central

    Peres, Lázaro Eustáquio Pereira

    2012-01-01

    Despite the wide use of plant regeneration for biotechnological purposes, the signals that allow cells to become competent to assume different fates remain largely unknown. Here, it is demonstrated that the Regeneration1 (Rg1) allele, a natural genetic variation from the tomato wild relative Solanum peruvianum, increases the capacity to form both roots and shoots in vitro; and that the gibberellin constitutive mutant procera (pro) presented the opposite phenotype, reducing organogenesis on either root-inducing medium (RIM) or shoot-inducing medium (SIM). Mutants showing alterations in the formation of specific organs in vitro were the auxin low-sensitivity diageotropica (dgt), the lateral suppresser (ls), and the KNOX-overexpressing Mouse ears (Me). dgt failed to form roots on RIM, Me increased shoot formation on SIM, and the high capacity for in vitro shoot formation of ls contrasted with its recalcitrance to form axillary meristems. Interestingly, Rg1 rescued the in vitro organ formation capacity in proRg1 and dgtRg1 double mutants and the ex vitro low lateral shoot formation in pro and ls. Such epistatic interactions were also confirmed in gene expression and histological analyses conducted in the single and double mutants. Although Me phenocopied the high shoot formation of Rg1 on SIM, it failed to increase rooting on RIM and to rescue the non-branching phenotype of ls. Taken together, these results suggest REGENERATION1 and the DELLA mutant PROCERA as controlling a common competence to assume distinct cell fates, rather than the specific induction of adventitious roots or shoots, which is controlled by DIAGEOTROPICA and MOUSE EARS, respectively. PMID:22915742

  14. The tomato (Solanum lycopersicum cv. Micro-Tom) natural genetic variation Rg1 and the DELLA mutant procera control the competence necessary to form adventitious roots and shoots.

    PubMed

    Lombardi-Crestana, Simone; da Silva Azevedo, Mariana; e Silva, Geraldo Felipe Ferreira; Pino, Lílian Ellen; Appezzato-da-Glória, Beatriz; Figueira, Antonio; Nogueira, Fabio Tebaldi Silveira; Peres, Lázaro Eustáquio Pereira

    2012-09-01

    Despite the wide use of plant regeneration for biotechnological purposes, the signals that allow cells to become competent to assume different fates remain largely unknown. Here, it is demonstrated that the Regeneration1 (Rg1) allele, a natural genetic variation from the tomato wild relative Solanum peruvianum, increases the capacity to form both roots and shoots in vitro; and that the gibberellin constitutive mutant procera (pro) presented the opposite phenotype, reducing organogenesis on either root-inducing medium (RIM) or shoot-inducing medium (SIM). Mutants showing alterations in the formation of specific organs in vitro were the auxin low-sensitivity diageotropica (dgt), the lateral suppresser (ls), and the KNOX-overexpressing Mouse ears (Me). dgt failed to form roots on RIM, Me increased shoot formation on SIM, and the high capacity for in vitro shoot formation of ls contrasted with its recalcitrance to form axillary meristems. Interestingly, Rg1 rescued the in vitro organ formation capacity in proRg1 and dgtRg1 double mutants and the ex vitro low lateral shoot formation in pro and ls. Such epistatic interactions were also confirmed in gene expression and histological analyses conducted in the single and double mutants. Although Me phenocopied the high shoot formation of Rg1 on SIM, it failed to increase rooting on RIM and to rescue the non-branching phenotype of ls. Taken together, these results suggest REGENERATION1 and the DELLA mutant PROCERA as controlling a common competence to assume distinct cell fates, rather than the specific induction of adventitious roots or shoots, which is controlled by DIAGEOTROPICA and MOUSE EARS, respectively.

  15. Phenotypic characterization, genetic mapping and candidate gene analysis of a source conferring reduced plant height in sunflower.

    PubMed

    Ramos, María Laura; Altieri, Emiliano; Bulos, Mariano; Sala, Carlos A

    2013-01-01

    Reduced height germplasm has the potential to increase stem strength, standability, and also yields potential of the sunflower crop (Helianthus annuus L. var. macrocarpus Ckll.). In this study, we report on the inheritance, mapping, phenotypic and molecular characterization of a reduced plant height trait in inbred lines derived from the source DDR. This trait is controlled by a semidominant allele, Rht1, which maps on linkage group 12 of the sunflower public consensus map. Phenotypic effects of this allele include shorter height and internode length, insensibility to exogenous gibberellin application, normal skotomorphogenetic response, and reduced seed set under self-pollination conditions. This later effect presumably is related to the reduced pollen viability observed in all DDR-derived lines studied. Rht1 completely cosegregated with a haplotype of the HaDella1 gene sequence. This haplotype consists of a point mutation converting a leucine residue in a proline within the conserved DELLA domain. Taken together, the phenotypic, genetic, and molecular results reported here indicate that Rht1 in sunflower likely encodes an altered DELLA protein. If the DELPA motif of the HaDELLA1 sequence in the Rht1-encoded protein determines by itself the observed reduction in height is a matter that remains to be investigated.

  16. The non-gibberellic acid-responsive semi-dwarfing gene uzu affects Fusarium crown rot resistance in barley

    PubMed Central

    2014-01-01

    Background Studies in Arabidopsis show that DELLA genes may differentially affect responses to biotrophic and necrophic pathogens. A recent report based on the study of DELLA-producing reduced height (Rht) genes in wheat and barley also hypothesized that DELLA genes likely increased susceptibility to necrotrophs but increased resistance to biotrophs. Results Effects of uzu, a non-GA (gibberellic acid)-responsive semi-dwarfing gene, on Fusarium crown rot (FCR) resistance in barley were investigated. Fifteen pairs of near isogenic lines for this gene were generated and assessed under two different temperature regimes. Similar to its impacts on plant height, the semi-dwarfing gene uzu also showed larger effects on FCR severity in the high temperature regime when compared with that in the low temperature regime. Conclusions Results from this study add to the growing evidence showing that the effects of plant height on Fusarium resistances are unlikely related to DELLA genes but due to direct or indirect effects of height difference per se. The interaction between these two characteristics highlights the importance of understanding relationships between resistance and other traits of agronomic importance as the value of a resistance gene could be compromised if it dramatically affects plant development and morphology. PMID:24418007

  17. Redescription of two European species of Acerentomidae (Protura) belonging to the Italian fauna.

    PubMed

    Galli, Loris; Capurro, Matteo; Costa, Fabio; Stadio, Gabriele Di; Sarà, Antonio; Zinni, Matteo

    2016-08-22

    Acerentulus apuliacus Rusek & Stumpp, 1988 is redescribed based on new specimens collected in Apulia and Basilicata (S-Italy) and deposited in the collection of Geneva Natural History Museum. Podolinella ruseki (Nosek, 1967) new combination is redescribed, based on the holotype from Austria and additional specimens collected in Liguria, NW Italy. The new material is deposited in the collection of the Dipartimento di Scienze della Terra, dell'Ambiente e della Vita, University of Genoa.

  18. The Art of Necessity: Pictures of Lives Reclaimed from Trauma

    ERIC Educational Resources Information Center

    Wexler, Alice

    2004-01-01

    Since opening in 1999, the art studio at the Northeast Center for Special Care (NCSC) serves as a reprieve from the tragedy of loss that pervades every corner of the facility. Working for over two decades with people who have a wide range of disabilities, artist Bill Richards creates a charmed space in the NCSC studio. The neighbors, as they are…

  19. Modeling and 3D Visualization for Evaluation of Anti-Terrorism/Force Protection Alternatives: Phase II Final Report

    DTIC Science & Technology

    2006-11-21

    SCHOOL Monterey, California 93943-5000 COL David A. Smarsh, USAF Dr. Leonard A. Ferrari Acting President...1.3.6 Planet 9 Studios David Colleen, CEO Chris Greuel, 3D Model Engineer Dan Ancona, Documentation and Training Carlos Newcomb, 3D Imagery...informational forum of M&S professionals working in the service of naval installation security. David Colleen, CEO, Planet 9 Studios, gave a

  20. Tight versus standard blood pressure control in patients with hypertension with and without cardiovascular disease.

    PubMed

    Reboldi, Gianpaolo; Angeli, Fabio; de Simone, Giovanni; Staessen, Jan A; Verdecchia, Paolo

    2014-03-01

    An excessive blood pressure (BP) reduction might be dangerous in high-risk patients with cardiovascular disease. In the Studio Italiano Sugli Effetti CARDIOvascolari del Controllo della Pressione Arteriosa SIStolica (Cardio-Sis), 1111 nondiabetic patients with systolic BP ≥150 mm Hg were randomly assigned to a systolic BP target <140 mm Hg (standard control) or <130 mm Hg (tight control). We stratified patients by absence (n=895) or presence (n=216) of established cardiovascular disease at entry. Antihypertensive treatment was open-label and tailored to each patient's needs. After 2-year follow-up, the primary end point of the study, electrocardiographic left ventricular hypertrophy, occurred less frequently in the tight than in the standard control group in the patients without (10.8% versus 15.2%) and with (14.1% versus 23.5%) established cardiovascular disease (P for interaction=0.82). The main secondary end point, a composite of cardiovascular events and all-cause death, occurred less frequently in the tight than in the standard control group both in patients without (1.47 versus 3.68 patient-years; P=0.016) and with (7.87 versus 11.22 patient-years; P=0.049) previous cardiovascular disease. In a multivariable Cox model, allocation to tight BP control reduced the risk of cardiovascular events to a similar extent in patients with or without overt cardiovascular disease at randomization (P for interaction=0.43). In conclusion, an intensive treatment aimed to lower systolic BP<130 mm Hg reduced left ventricular hypertrophy and improved clinical outcomes to a similar extent in patients with hypertension and without established cardiovascular disease.

  1. Mountain Infantry - Is There a Need?

    DTIC Science & Technology

    1988-06-03

    Valley and was used extensively by the Germans. The 9objective of the mountaineers was the Monte Belvedere- Monte Della Torraccia Ridge network which...hopes of attaining surprise. The 85th conducted a frontal attack against Monte Belvedere and Monte Gorgolesco, while the 87th attacked up the western...fought a bloody battle the last 300 yards from the summit of both mountains. Monte Della Torraccia proved to be a tough fight. On the afternoon of the

  2. [Linee guida italiane per il trattamento dell'alcolismo].

    PubMed

    Ceccanti, Mauro; Iannitelli, Angela; Fiore, Marco

    2018-01-01

    RIASSUNTO. L'Europa è la regione con il più forte consumo di alcol al mondo, con la più elevata percentuale di malattie totali e morti premature alcol-correlate. In Italia, questo fenomeno coinvolge circa il 13% della popolazione oltre i 18 anni e oltre il 25% dei pazienti ospedalizzati. Sfortunatamente, solo il 5% di questi pazienti vengono riconosciuti come persone affette da disturbo da uso di alcol (DUA). Una scarsa conoscenza della malattia, la mancanza di accesso alle cure e le poche risorse messe a disposizione nella gestione del problema sono tra le principali cause di ritardo nella diagnosi, alla fine con conseguenze cliniche molto più importanti e costose da gestire. Alla luce di ciò, abbiamo deciso di dedicare questo numero speciale della Rivista di psichiatria a una serie di articoli riguardanti le linee guida italiane per il trattamento della dipendenza da alcol. Realizzate in collaborazione con numerosi esperti e importanti società scientifiche italiane come il Centro di Riferimento Alcologico della Regione Lazio (CRARL), la Società Italiana Tossicodipendenze (SITD), la Società italiana per il Trattamento dell'Alcolismo e le sue Complicanze (SITAC), la Società Italiana Psichiatria delle Dipendenze (SIPDip), la Società Italiana Patologie da Dipendenza (SIPaD) e l'Istituto di Biologia Cellulare e Neurobiologia (IBCN-CNR), queste linee guida forniscono agli operatori una serie di raccomandazioni basate su prove di efficacia volte ad aumentare la conoscenza e un uso appropriato dei farmaci per le persone affette da DUA. Con la possibilità di un continuo aggiornamento, l'obiettivo principale di queste linee guida sarà quello di garantire l'omogeneità dei trattamenti e un incremento qualitativo nell'assistenza dei pazienti affetti da DUA, così da ridurre le conseguenze psicosociali e sulla salute pubblica di questa importante malattia psichiatrica.

  3. Comprehensive gene expression analysis of rice aleurone cells: probing the existence of an alternative gibberellin receptor.

    PubMed

    Yano, Kenji; Aya, Koichiro; Hirano, Ko; Ordonio, Reynante Lacsamana; Ueguchi-Tanaka, Miyako; Matsuoka, Makoto

    2015-02-01

    Current gibberellin (GA) research indicates that GA must be perceived in plant nuclei by its cognate receptor, GIBBERELLIN INSENSITIVE DWARF1 (GID1). Recognition of GA by GID1 relieves the repression mediated by the DELLA protein, a model known as the GID1-DELLA GA perception system. There have been reports of potential GA-binding proteins in the plasma membrane that perceive GA and induce α-amylase expression in cereal aleurone cells, which is mechanistically different from the GID1-DELLA system. Therefore, we examined the expression of the rice (Oryza sativa) α-amylase genes in rice mutants impaired in the GA receptor (gid1) and the DELLA repressor (slender rice1; slr1) and confirmed their lack of response to GA in gid1 mutants and constitutive expression in slr1 mutants. We also examined the expression of GA-regulated genes by genome-wide microarray and quantitative reverse transcription-polymerase chain reaction analyses and confirmed that all GA-regulated genes are modulated by the GID1-DELLA system. Furthermore, we studied the regulatory network involved in GA signaling by using a set of mutants defective in genes involved in GA perception and gene expression, namely gid1, slr1, gid2 (a GA-related F-box protein mutant), and gamyb (a GA-related trans-acting factor mutant). Almost all GA up-regulated genes were regulated by the four named GA-signaling components. On the other hand, GA down-regulated genes showed different expression patterns with respect to GID2 and GAMYB (e.g. a considerable number of genes are not controlled by GAMYB or GID2 and GAMYB). Based on these observations, we present a comprehensive discussion of the intricate network of GA-regulated genes in rice aleurone cells. © 2015 American Society of Plant Biologists. All Rights Reserved.

  4. Comprehensive Gene Expression Analysis of Rice Aleurone Cells: Probing the Existence of an Alternative Gibberellin Receptor1

    PubMed Central

    Yano, Kenji; Aya, Koichiro; Hirano, Ko; Ordonio, Reynante Lacsamana; Ueguchi-Tanaka, Miyako; Matsuoka, Makoto

    2015-01-01

    Current gibberellin (GA) research indicates that GA must be perceived in plant nuclei by its cognate receptor, GIBBERELLIN INSENSITIVE DWARF1 (GID1). Recognition of GA by GID1 relieves the repression mediated by the DELLA protein, a model known as the GID1-DELLA GA perception system. There have been reports of potential GA-binding proteins in the plasma membrane that perceive GA and induce α-amylase expression in cereal aleurone cells, which is mechanistically different from the GID1-DELLA system. Therefore, we examined the expression of the rice (Oryza sativa) α-amylase genes in rice mutants impaired in the GA receptor (gid1) and the DELLA repressor (slender rice1; slr1) and confirmed their lack of response to GA in gid1 mutants and constitutive expression in slr1 mutants. We also examined the expression of GA-regulated genes by genome-wide microarray and quantitative reverse transcription-polymerase chain reaction analyses and confirmed that all GA-regulated genes are modulated by the GID1-DELLA system. Furthermore, we studied the regulatory network involved in GA signaling by using a set of mutants defective in genes involved in GA perception and gene expression, namely gid1, slr1, gid2 (a GA-related F-box protein mutant), and gamyb (a GA-related trans-acting factor mutant). Almost all GA up-regulated genes were regulated by the four named GA-signaling components. On the other hand, GA down-regulated genes showed different expression patterns with respect to GID2 and GAMYB (e.g. a considerable number of genes are not controlled by GAMYB or GID2 and GAMYB). Based on these observations, we present a comprehensive discussion of the intricate network of GA-regulated genes in rice aleurone cells. PMID:25511432

  5. Orientamento della prima fase della moschea al-Aqşā di Gerusalemme

    NASA Astrophysics Data System (ADS)

    Di Cesare, Michelina

    2017-07-01

    A new interpretation of the archaeological data regarding the first of the three pre-Crusader structural phases of al-Aqşā mosque in Jerusalem (Aqşā I) is proposed. It suggests that the building had an astronomical orientation like other 7th-century and early 8th-century mosques. Thus, Aqşā I would have been oriented towards the East rather than the South, as believed so far. This hypothesis would allow to solve the anomalies of the plan of Aqşā I. Indeed, by identifying the eastern wall rather than the southern as the qiblī wall, the aisles would not result perpendicular but parallel to it and running along the long side, as usual in Umayyad mosques. Consequently, the precocious appearance of the transept in Aqşā II would be due to the re-orientation of the previous structure.

  6. EventSlider User Manual

    DTIC Science & Technology

    2016-09-01

    is a Windows Presentation Foundation (WPF) control developed using the .NET framework in Microsoft Visual Studio. As a WPF control, it can be used in...any WPF application as a graphical visual element. The purpose of the control is to visually display time-related events as vertical lines on a...available on the control. 15. SUBJECT TERMS Windows Presentation Foundation, WPF, control, C#, .NET framework, Microsoft Visual Studio 16. SECURITY

  7. Studio Approaches to Art Therapy.

    ERIC Educational Resources Information Center

    Malchiodi, Cathy A.

    A need exists within the profession of art therapy to address issues of managed care, licensure, and provider reimbursement. While the profession struggles on both the state and national level with issues of livelihood and recognition, there are still philosophical questions within the field which remain unexplored. This article addresses a theme…

  8. Student Experiences with Studio Instruction

    ERIC Educational Resources Information Center

    Upitis, Rena; Abrami, Philip C.; Varela, Wynnpaul; King, Matthew; Brook, Julia

    2017-01-01

    The purpose of the study was to examine students' experiences of independent music lessons, and to ascertain what factors predicted enjoyment and success, especially those predictors arising from self-regulation learning theory. A self-report survey was used to gather data on student demographics, practising habits, musical skills, achievements,…

  9. Aspirin in polycythemia vera and essential thrombocythemia: current facts and perspectives.

    PubMed

    Landolfi, R; Patrono, C

    1996-09-01

    The role of aspirin in the antithrombotic strategy of patients with polycythemia vera (PV) and essential thrombocythemia (ET) is highly controversial. Long considered unsafe on the basis of a single clinical trial testing very high doses in PV patients, aspirin is being increasingly used at lower dosage. The rationale for the use of aspirin in patients with PV and ET is provided by the efficacy of this agent in the treatment of microcirculatory disturbances of thrombocythemic states associated with myeloproliferative disorders and by recent evidence that asymptomatic PV and ET patients have persistently increased thromboxane (TX) A2-biosynthesis. This increase, which most likely reflects enhanced platelet activation in vivo, is independent of the platelet mass and blood viscosity and largely supressed by a short term low-dose aspirin regimen (50 mg/day for 7 days). Since enhanced TXA2 biosynthesis may play a role in transducing the increased thrombotic risk associated with PV and ET, long-term low-dose aspirin administration has been proposed as a possible antithombotic strategy in these subjects. The safety of this treatment in PV patients has been recently reassessed by the Gruppo Italiano per lo Studio della Policitemia Vera (GISP) which has followed for over one year 112 patients randomized to receive 40 mg/day aspirin or placebo. In the same study, serum TXB2 measurements provided evidence that the low-dose aspirin regimen tested was fully effective in inhibiting platelet cyclooxygenase activity. On this basis, a large scale trial aimed at assessing the antithrombotic efficacy of this approach is currently being organized. In patients with ET both the minimal aspirin dose required for complete inhibition of platelet cyclooxygenase and the safety of long-term aspirin administration need to be established prior to extensive clinical evaluation of this strategy.

  10. Regular wine consumption in chronic heart failure: impact on outcomes, quality of life, and circulating biomarkers.

    PubMed

    Cosmi, Franco; Di Giulio, Paola; Masson, Serge; Finzi, Andrea; Marfisi, Rosa Maria; Cosmi, Deborah; Scarano, Marco; Tognoni, Gianni; Maggioni, Aldo P; Porcu, Maurizio; Boni, Silvana; Cutrupi, Giovanni; Tavazzi, Luigi; Latini, Roberto

    2015-05-01

    Moderate, regular alcohol consumption is generally associated with a lower risk of cardiovascular events but data in patients with chronic heart failure are scarce. We evaluated the relations between wine consumption, health status, circulating biomarkers, and clinical outcomes in a large Italian population of patients with chronic heart failure enrolled in a multicenter clinical trial. A brief questionnaire on dietary habits was administered at baseline to 6973 patients enrolled in the Gruppo Italiano per lo Studio della Sopravvivenza nell'Insufficienza Cardiaca-Heart Failure (GISSI-HF) trial. The relations between wine consumption, fatal and nonfatal clinical end points, quality of life, symptoms of depression, and circulating biomarkers of cardiac function and inflammation (in subsets of patients) were evaluated with simple and multivariable-adjusted statistical models. Almost 56% of the patients reported drinking at least 1 glass of wine per day. After adjustment, clinical outcomes were not significantly different in the predefined 4 groups of wine consumption. However, patients with more frequent wine consumption had a significantly better perception of health status (Kansas City Cardiomyopathy Questionnaire score, adjusted P<0.0001), less frequent symptoms of depression (Geriatric Depression Scale, adjusted P=0.01), and lower plasma levels of biomarkers of vascular inflammation (osteoprotegerin and C-terminal proendothelin-1, adjusted P<0.0001, and pentraxin-3, P=0.01) after adjusting for possible confounders. We show for the first time in a large cohort of patients with chronic heart failure that moderate wine consumption is associated with a better perceived and objective health status, lower prevalence of depression, and less vascular inflammation, but does not translate into more favorable clinical 4-year outcomes. URL: http://www.clinicaltrials.gov. Unique identifier: NCT0033633. © 2015 American Heart Association, Inc.

  11. Reducing the failure rate in introductory physics classes

    NASA Astrophysics Data System (ADS)

    Saul, Jeff; Coulombe, Patrick; Lindell, Rebecca

    2017-01-01

    Calculus-based introductory physics courses are often among the most difficult at many colleges and universities. With the national movement to increase STEM majors, the introductory calculus-based courses need to be less of a weed-out course and more of a course that propels students forward into successful majors. This talk discusses two approaches to reduce DFW rates and improve student retention: studio courses and parachute courses. Studio courses integrate lecture/laboratory into one course where the primary mode of instruction is small group activities. Typically, any students enrolled in the college or university can enroll in a studio version of the course. Parachute courses on the other hand, focus on the poor performing students. Designed so that students not doing well in an introductory physics course can switch into the parachute class mid-semester without harm to their GPA. In addition, the parachute course focuses on helping students build the knowledge and skills necessary for success when retaking the calculus-based Physics course. The studio course format has been found to reduce DFW rates at several universities by 40-60% compared with separate lecture and laboratory format versions of the same courses, while parachutes courses were less successful. At one university, the parachute course succeeded in helping 80% of students maintain their GPA, but only helped 20% successfully pass the calculus-based physics course.

  12. Elettrodinamica classica

    NASA Astrophysics Data System (ADS)

    Lechner, Kurt

    Nella scoperta della Relatività Ristretta l'Elettrodinamica, rappresentando una teoria relativistica per eccellenza, ha giocato un ruolo fondamentale. Il principio di relativit` a einsteiniana, che afferma che tutte le leggi della fisica devono avere la stessa forma in tutti i sistemi di riferimento inerziali, è emerso con forza da questa teoria ed è andato consolidandosi sempre di più, man mano che le nostre conoscenze del mondo microscopico sono diventate più complete: tutte le interazioni fondamentali rispettano infatti tale principio. Il modo più semplice ed elegante per implementarlo — difatti l'unico di un'utilità concreta — è rappresentato dal paradigma della covarianza a vista nell'ambito del calcolo tensoriale. Questo paradigma è stato applicato con successo a tutte le teorie di carattere fondamentale, come le teorie che descrivono le quattro interazioni fondamentali e le più speculative teorie di superstringa, e mantiene la sua piena efficacia anche in teoria quantistica. La nostra esposizione dell'Elettrodinamica classica si baserà dunque a ragione su questo paradigma.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roth, Amir; Goldwasser, David; Parker, Andrew

    The OpenStudio software development kit has played a significant role in the adoption of the EnergyPlus whole building energy modeling engine and in the development and launch of new applications that use EnergyPlus for a variety of purposes, from design to auditing to code compliance and management of large portfolios. One of the most powerful features of the OpenStudio platform is Measure, a scripting facility similar to Excel's Visual Basic macros. Measures can be used to apply energy conservation measures to models--hence the name--to create reports and visualizations, and even to sew together custom workflows. Measures automate tedious tasks increasingmore » modeler productivity and reducing error. Measures have also become a currency in the OpenStudio tools ecosystem, a way to codify knowledge and protocol and transfer it from one modeler to another, either within an organization or within the global modeling community. This paper describes some of the many applications of Measures.« less

  14. A computer graphics reconstruction and optical analysis of scale anomalies in Caravaggio's Supper at Emmaus

    NASA Astrophysics Data System (ADS)

    Stork, David G.; Furuichi, Yasuo

    2011-03-01

    David Hockney has argued that the right hand of the disciple, thrust to the rear in Caravaggio's Supper at Emmaus (1606), is anomalously large as a result of the artist refocusing a putative secret lens-based optical projector and tracing the image it projected onto his canvas. We show through rigorous optical analysis that to achieve such an anomalously large hand image, Caravaggio would have needed to make extremely large, conspicuous and implausible alterations to his studio setup, moving both his purported lens and his canvas nearly two meters between "exposing" the disciple's left hand and then his right hand. Such major disruptions to his studio would have impeded -not aided- Caravaggio in his work. Our optical analysis quantifies these problems and our computer graphics reconstruction of Caravaggio's studio illustrates these problems. In this way we conclude that Caravaggio did not use optical projections in the way claimed by Hockney, but instead most likely set the sizes of these hands "by eye" for artistic reasons.

  15. DaVinci's Mona Lisa entering the next dimension.

    PubMed

    Carbon, Claus-Christian; Hesslinger, Vera M

    2013-01-01

    For several of Leonardo da Vinci's paintings, such as The Virgin and Child with St Anne or the Mona Lisa, there exist copies produced by his own studio. In case of the Mona Lisa, a quite exceptional, rediscovered studio copy was presented to the public in 2012 by the Prado Museum in Madrid. Not only does it mirror its famous counterpart superficially; it also features the very same corrections to the lower layers, which indicates that da Vinci and the 'copyist' must have elaborated their panels simultaneously. On the basis of subjective (thirty-two participants estimated painter-model constellations) as well as objective data (analysis of trajectories between landmarks of both paintings), we revealed that both versions differ slightly in perspective. We reconstructed the original studio setting and found evidence that the disparity between both paintings mimics human binocular disparity. This points to the possibility that the two Giocondas together might represent the first stereoscopic image in world history.

  16. Mirrors in early clinical photography (1862-1882): a descriptive study.

    PubMed

    Horgmo, Øystein H

    2015-01-01

    In the mid-nineteenth century, photographers used mirrors to document different views of a patient in the same image. The first clinical photographs were taken by portrait photographers. As conventions for clinical photography were not yet established, early clinical photographs resemble contemporary portraits. The use of mirrors in clinical photography probably originated from the portrait studios, as several renowned photographers employed mirrors in their studio portraits. Clinical photographs taken for the US Army Medical Museum between 1862 and 1882 show different ways of employing this mirror technique.

  17. Use of 3D techniques for virtual production

    NASA Astrophysics Data System (ADS)

    Grau, Oliver; Price, Marc C.; Thomas, Graham A.

    2000-12-01

    Virtual production for broadcast is currently mainly used in the form of virtual studios, where the resulting media is a sequence of 2D images. With the steady increase of 3D computing power in home PCs and the technical progress in 3D display technology, the content industry is looking for new kinds of program material, which makes use of 3D technology. The applications range form analysis of sport scenes, 3DTV, up to the creation of fully immersive content. In a virtual studio a camera films one or more actors in a controlled environment. The pictures of the actors can be segmented very accurately in real time using chroma keying techniques. The isolated silhouette can be integrated into a new synthetic virtual environment using a studio mixer. The resulting shape description of the actors is 2D so far. For the realization of more sophisticated optical interactions of the actors with the virtual environment, such as occlusions and shadows, an object-based 3D description of scenes is needed. However, the requirements of shape accuracy, and the kind of representation, differ in accordance with the application. This contribution gives an overview of requirements and approaches for the generation of an object-based 3D description in various applications studied by the BBC R and D department. An enhanced Virtual Studio for 3D programs is proposed that covers a range of applications for virtual production.

  18. A Simple Probabilistic Approach to Classification and Routing

    DTIC Science & Technology

    1996-05-01

    music passage has many music related words such as ’studio’, ’ album ’, ’disc’, and ’record’, and the sports passage has many sports...about music , even though the word ’ music ’ is not in the passage. Similarly, most people can tell that the second passage is from a sports article, even...though the word ’sport’ is never mentioned. "Before the release of his last studio album , 1993’s ’Ten Summoner’s Tales’, Sting commented that

  19. Impact of thistle rennet from Carlina acanthifolia All. subsp. acanthifolia on bacterial diversity and dynamics of a specialty Italian raw ewes' milk cheese.

    PubMed

    Cardinali, Federica; Osimani, Andrea; Taccari, Manuela; Milanović, Vesna; Garofalo, Cristiana; Clementi, Francesca; Polverigiani, Serena; Zitti, Silvia; Raffaelli, Nadia; Mozzon, Massimo; Foligni, Roberta; Franciosi, Elena; Tuohy, Kieran; Aquilanti, Lucia

    2017-08-16

    Caciofiore della Sibilla is an Italian specialty soft cheese manufactured with Sopravissana raw ewes' milk and thistle rennet prepared with young fresh leaves and stems of Carlina acanthifolia All. subsp. acanthifolia, according to an ancient tradition deeply rooted in the territory of origin (mountainous hinterland of the Marche region, Central Italy). In this study, the impact of thistle rennet on the bacterial dynamics and diversity of Caciofiore della Sibilla cheese was investigated by applying a polyphasic approach based on culture and DNA-based techniques (Illumina sequencing and PCR-DGGE). A control cheese manufactured with the same batch of ewes' raw milk and commercial animal rennet was analyzed in parallel. Overall, a large number of bacterial taxa were identified, including spoilage, environmental and pro-technological bacteria, primarily ascribed to Lactobacillales. Thistle rennet was observed clearly to affect the early bacterial dynamics of Caciofiore della Sibilla cheese with Lactobacillus alimentarius/paralimentarius and Lactobacillus plantarum/paraplantarum/pentosus being detected in the phyllosphere of C. acanthifolia All., thistle rennet and curd obtained with thistle rennet. Other bacterial taxa, hypothetically originating from the vegetable coagulant (Enterococcus faecium, Lactobacillus brevis, Lactobacillus delbrueckii, Leuconostoc mesenteroides/pseudomesenteroides), were exclusively found in Caciofiore della Sibilla cheese by PCR-DGGE. At the end of the maturation period, Illumina sequencing demonstrated that both cheeses were dominated by Lactobacillales; however curd and cheese produced with thistle rennet were co-dominated by Lactobacillus and Leuconostoc, whereas Lactoccous prevailed in curd and cheese produced with commercial animal rennet followed by Lactobacillus. Differences in the bacterial composition between the two cheeses at the end of their maturation period were confirmed by PCR-DGGE analysis. Copyright © 2017 Elsevier B

  20. Smoking in contemporary American cinema.

    PubMed

    Omidvari, Karan; Lessnau, Klaus; Kim, Jeannie; Mercante, Donald; Weinacker, Ann; Mason, Carol

    2005-08-01

    The true prevalence of smoking among characters portrayed in the movies is unknown. This study examines this prevalence objectively. The top 10 movies on the weekly box office charts were reviewed. Whether or not the top five characters in these movies smoked, was documented. It was determined prior to the start of the study that 300 male characters and 300 female characters were needed to detect any significant difference. A total of 447 movies, composed of 193 movies rated restricted (R) [children < 17 years of age must be accompanied by an adult], 131 movies rated PG13 for parental guidance suggested for children < 13 years of age (PG) and 123 movies rated PG for parental guidance suggested, were examined until the sample size was reached. Smoking prevalence is the same in contemporary American movies and in the general US population (23.3% vs 24.8%, respectively). However, there was more smoking in these movies among men than among women (25.5% vs 20.5%, respectively; p < 0.006), among antagonists than among protagonists (35.7% vs 20.6%, respectively; p < 0.001), lower vs middle vs upper socioeconomic class (SEC) [48.2%, 22.9%, and 10.5%, respectively; p < 0.001], among independent vs studio movies (46.2% vs 18.2%, respectively; p < 0.001); and among R-rated vs PG13-rated vs PG-rated movies (37.3%, 16.2%, and 8.1%, respectively; p < 0.001). In R-rated movies, and in both subcategories of R-rated studio movies and R-rated independent movies, smoking prevalence is higher than in the US population (37.3%, 30.5%, and 50.6% vs 24.8%, respectively; p < 0.001 for all). Additionally, compared to the US population, men, women and lower SEC members smoke more in R-rated movies, R-rated studio movies, and R-rated independent movies. In R-rated movies, antagonists smoke more than protagonists (43.9% vs 35.8%, respectively; p < 0.001), and whites smoke more than nonwhites (38.3% vs 26.4%, respectively; p < 0.001). In R-rated studio movies, antagonists smoke more than

  1. Plant hormones in arbuscular mycorrhizal symbioses: an emerging role for gibberellins.

    PubMed

    Foo, Eloise; Ross, John J; Jones, William T; Reid, James B

    2013-05-01

    Arbuscular mycorrhizal symbioses are important for nutrient acquisition in >80 % of terrestrial plants. Recently there have been major breakthroughs in understanding the signals that regulate colonization by the fungus, but the roles of the known plant hormones are still emerging. Here our understanding of the roles of abscisic acid, ethylene, auxin, strigolactones, salicylic acid and jasmonic acid is discussed, and the roles of gibberellins and brassinosteroids examined. Pea mutants deficient in gibberellins, DELLA proteins and brassinosteroids are used to determine whether fungal colonization is altered by the level of these hormones or signalling compounds. Expression of genes activated during mycorrhizal colonization is also monitored. Arbuscular mycorrhizal colonization of pea roots is substantially increased in gibberellin-deficient na-1 mutants compared with wild-type plants. This is reversed by application of GA3. Mutant la cry-s, which lacks gibberellin signalling DELLA proteins, shows reduced colonization. These changes were parallelled by changes in the expression of genes associated with mycorrhizal colonization. The brassinosteroid-deficient lkb mutant showed no change in colonization. Biologically active gibberellins suppress arbuscule formation in pea roots, and DELLA proteins are essential for this response, indicating that this role occurs within the root cells.

  2. Efficacy and tolerability of a new synergized pyrethrins thermofobic foam in comparison with benzyl benzoate in the treatment of scabies in convicts: the ISAC study (Studio Della scabbia in ambiente carcerario).

    PubMed

    Biele, M; Campori, G; Colombo, R; De Giorgio, G; Frascione, P; Sali, R; Starnini, G; Milani, M

    2006-07-01

    Scabies is a very common skin infection in convicts. The SIMSPE Society (Società Italiana di Medicina e Sanità Penitenziaria) has organized and conducted a multicentre, randomized, comparative, parallel group, investigator-blinded trial to evaluate the efficacy and tolerability of synergized pyrethrins foam (PF) in comparison with benzyl benzoate (BB) lotion. A total of 240 convicted patients, enrolled in eight National Jail Institutions, with a clinical diagnosis of scabies, were treated with PF (n = 120) for three consecutive days or BB (n = 120) for five consecutive days. Primary study endpoints were the clinical cure rate and the local tolerability. Secondary endpoints were clinical evolution of scabietic lesions and itching intensity. Study outcomes were assessed using appropriate semiquantitative scores at baseline and after 2 and 4 weeks. A second treatment cycle was applied if after 2 weeks the patient was not judged clinically cured. At week 2, a total of 75% (95% CI: 66-82%) and 71% (95% CI: 62-78%) of patients showed a complete clinical cure rate in the PF and BB groups, respectively. At week 4, the percentage of totally cured patients increased up to 95% (95% CI: 89-97%) and 91% (95% CI: 83-94%) in the PF and BB groups, respectively (P = NS between groups). At week 4, 5% in the PF group and 9% in the BB group complained of itching. Burning and irritation after treatment applications were more common in the BB group in comparison with the PF group. The tolerability score was better in the PF group in comparison with to BB group (2.9 vs. 2.2; P = 0.0001). A total of 95% of patients in the PV group had a good tolerability score (i.e. = 3) in comparison with 41% in the BB group. Our results show that a 3-day treatment with pyrethrins thermofobic foam is at least as effective as a 5-day treatment with benzyl benzoate lotion in convicted subjects with scabies. The foam formulation is better tolerated than the benzyl benzoate lotion.

  3. Urban Renewable Building And Neighborhood Optimization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    URBANopt is a user interface for creating and running district and city scale building energy simulations. The framework is built around the OpenStudio Urban Measures which are part of the OpenStudio project. Building footprints, building height, building type, and other data can be imported from public records or other sources. Footprints and locations for new buildings and district systems can also be specified. OpenStudio Measures are used to create starting point energy models and to model energy design features and efficiency measures for each building. URBANopt allows a user to pose several scenarios such as “what if 30% of themore » commercial retail buildings added roof top solar” or “what if all elementary schools converted to ground source heat pumps” and then visualize the impacts at a district or city scale. URBANopt is capable of modeling existing buildings, new construction, and district energy systems. URBANopt can be used to explore options for achieving Zero Energy across a collection of buildings (e.g., Zero Energy Districts).« less

  4. [Teledermatology--experiences from Northern Norway].

    PubMed

    Moseng, D

    2000-06-20

    Distant diagnosing by two-way interactive motion video (videoconference) appeared in the 1980s, the last four years with weekly teleconsultations to Hammerfest and Kirkenes. Patients are mostly referred from general practitioners. A physician with a 20% position is responsible for organising the videoconferences and participates in the consultation. A close-up camera is used for detailed examination of skin lesions. Photographs of skin areas may be transmitted directly to the specialist screen (still images). The studio physician writes prescriptions and sick leave notes. The specialist writes a reply to the referring physician. Referrals using still images are as yet at a pilot stage. Patients view early diagnosis, time saved, reduced costs, and less need for leave from work as important advantages with videoconferences. Patient satisfaction is high, although 10% are dissatisfied. Having a physician in the studio makes patients feel safer, and they understand the specialist better. This is a new role for the specialist; the doctor/patient relationship is often taken care of by the studio physician. Comparisons between videoconference and face-to-face consultations have shown up to 90% diagnostic agreement. A pilot study using still image referrals showed similar results. Videoconferences are well suited in everyday dermatology, when follow-up by specialist is necessary, and for patients in regular treatment at local clinics for skin disease. Still image referral seems promising. The studio physician's diagnostic abilities are enhanced. Many patients are not suited for teleconsultation, but telemedical solutions will have a role in the years to come.

  5. Integrated Vehicle Health Management Project-Modeling and Simulation for Wireless Sensor Applications

    NASA Technical Reports Server (NTRS)

    Wallett, Thomas M.; Mueller, Carl H.; Griner, James H., Jr.

    2009-01-01

    This paper describes the efforts in modeling and simulating electromagnetic transmission and reception as in a wireless sensor network through a realistic wing model for the Integrated Vehicle Health Management project at the Glenn Research Center. A computer model in a standard format for an S-3 Viking aircraft was obtained, converted to a Microwave Studio software format, and scaled to proper dimensions in Microwave Studio. The left wing portion of the model was used with two antenna models, one transmitting and one receiving, to simulate radio frequency transmission through the wing. Transmission and reception results were inconclusive.

  6. The Halo B2B Studio

    NASA Astrophysics Data System (ADS)

    Gorzynski, Mark; Derocher, Mike; Mitchell, April Slayden

    Research underway at Hewlett-Packard on remote communication resulted in the identification of three important components typically missing in existing systems. These missing components are: group nonverbal communication capabilities, high-resolution interactive data capabilities, and global services. Here we discuss some of the design elements in these three areas as part of the Halo program at HP, a remote communication system shown to be effective to end-users.

  7. A wideband absorber for television studios

    NASA Astrophysics Data System (ADS)

    Baird, M. D. M.

    The acoustic treatment in BBC television has taken various forms to date, all of which have been relatively expensive, some of which provide inadequate absorption. An investigation has been conducted into the possibilities of producing a new type of wideband absorber which would be more economic, also taking installation time into account, than earlier designs. This Report describes the absorption coefficient measurements made on various combinations of materials, from which a wideband sound absorber has been developed. The absorber works efficiently between 50 Hz and 10 kHz, is simple and easy to construct using readily available materials, and is fire resistant. The design lends itself, if necessary, to on-site fine tuning, and savings in the region of 50 percent can be achieved in terms of cost and space with respect to previous designs.

  8. Putting a Studio in the Mix

    ERIC Educational Resources Information Center

    Criswell, Chad

    2013-01-01

    Being able to record the work of young musicians is beneficial on a number of levels. From an educational standpoint, listening to recordings of rehearsals and performances can provide students with many different opportunities for critical evaluation and enhanced learning. The growth of digital music distribution in the past decade has sparked a…

  9. Idea Bank: A Classroom Recording Studio

    ERIC Educational Resources Information Center

    Schwartz, Emily

    2010-01-01

    Music education scholars and veteran teachers often assert that composition is an essential part of a child's participation in music, but like many music educators, the author was reluctant to include it as part of her daily beginning band curriculum. Time and money were limited, and she wanted to be sure to cover all the material that beginners…

  10. Long-distance transport of Gibberellic Acid Insensitive mRNA in Nicotiana benthamiana

    PubMed Central

    2013-01-01

    Background The Gibberellic Acid (GA) signal is governed by the GAI (Gibberellic Acid Insensitive) repressor, which is characterized by a highly conserved N-terminal DELLA domain. Deletion of the DELLA domain results in constitutive suppression of GA signaling. As the GAI transcript is transportable in phloem elements, a Δ-DELLA GAI (gai) transgenic stock plant can reduce the stature of a scion through transport of gai mRNA from the stock. However, little is known about the characteristics of a scion on a gai stock. Results Arabidopsis Δ-DELLA GAI (gai) was fused with a T7 epitope tag and expressed under the control of a companion cell-specific expression promoter, Commelina yellow mottle virus promoter (CoYMVp), to enhance transport in the phloem. The CoYMVp:Atgai-T7 (CgT) transgenic Nicotiana benthamiana exhibited a dwarf phenotype and lower sensitivity to GA enhancement of shoot stature. A wild-type (WT) scion on a CgT stock contained both Atgai-T7 mRNA and the translated product. Microarray analysis to clarify the effect of the CgT stock on the gene expression pattern in the scion clearly revealed that the WT scions on CgT stocks had fewer genes whose expression was altered in response to GA treatment. An apple rootstock variety, Malus prunifolia, integrating CoYMVp:Atgai moderately reduced the tree height of the apple cultivar scion. Conclusions Our results demonstrate that Atgai mRNA can move from companion cells to sieve tubes and that the translated product remains at the sites to which it is transported, resulting in attenuation of GA responses by reducing the expression of many genes. The induction of semi-dwarfism in an apple cultivar on root stock harbouring Atgai suggests that long-distance transport of mRNA from grafts would be applicable to horticulture crops. PMID:24144190

  11. Plant hormones in arbuscular mycorrhizal symbioses: an emerging role for gibberellins

    PubMed Central

    Foo, Eloise; Ross, John J.; Jones, William T.; Reid, James B.

    2013-01-01

    Background and Aims Arbuscular mycorrhizal symbioses are important for nutrient acquisition in >80 % of terrestrial plants. Recently there have been major breakthroughs in understanding the signals that regulate colonization by the fungus, but the roles of the known plant hormones are still emerging. Here our understanding of the roles of abscisic acid, ethylene, auxin, strigolactones, salicylic acid and jasmonic acid is discussed, and the roles of gibberellins and brassinosteroids examined. Methods Pea mutants deficient in gibberellins, DELLA proteins and brassinosteroids are used to determine whether fungal colonization is altered by the level of these hormones or signalling compounds. Expression of genes activated during mycorrhizal colonization is also monitored. Key Results Arbuscular mycorrhizal colonization of pea roots is substantially increased in gibberellin-deficient na-1 mutants compared with wild-type plants. This is reversed by application of GA3. Mutant la cry-s, which lacks gibberellin signalling DELLA proteins, shows reduced colonization. These changes were parallelled by changes in the expression of genes associated with mycorrhizal colonization. The brassinosteroid-deficient lkb mutant showed no change in colonization. Conclusions Biologically active gibberellins suppress arbuscule formation in pea roots, and DELLA proteins are essential for this response, indicating that this role occurs within the root cells. PMID:23508650

  12. Signed, sealed and delivered: "big tobacco" in Hollywood, 1927-1951.

    PubMed

    Lum, K L; Polansky, J R; Jackler, R K; Glantz, S A

    2008-10-01

    Smoking in movies is associated with adolescent and young adult smoking initiation. Public health efforts to eliminate smoking from films accessible to youth have been countered by defenders of the status quo, who associate tobacco imagery in "classic" movies with artistry and nostalgia. The present work explores the mutually beneficial commercial collaborations between the tobacco companies and major motion picture studios from the late 1920s through the 1940s. Cigarette endorsement contracts with Hollywood stars and movie studios were obtained from internal tobacco industry documents at the University of California, San Francisco (UCSF) Legacy Tobacco Documents Library and the Jackler advertising collection at Stanford. Cigarette advertising campaigns that included Hollywood endorsements appeared from 1927 to 1951, with major activity in 1931-2 and 1937-8 for American Tobacco Company's Lucky Strike, and in the late 1940s for Liggett & Myers' Chesterfield. Endorsement contracts and communication between American Tobacco and movie stars and studios explicitly reveal the cross-promotional value of the campaigns. American Tobacco paid movie stars who endorsed Lucky Strike cigarettes US$218,750 in 1937-8 (equivalent to US$3.2 million in 2008) for their testimonials. Hollywood endorsements in cigarette advertising afforded motion picture studios nationwide publicity supported by the tobacco industry's multimillion US dollar advertising budgets. Cross-promotion was the incentive that led to a synergistic relationship between the US tobacco and motion picture industries, whose artefacts, including "classic" films with smoking and glamorous publicity images with cigarettes, continue to perpetuate public tolerance of onscreen smoking. Market-based disincentives within the film industry may be a solution to decouple the historical association between Hollywood films and cigarettes.

  13. simuwatt - A Tablet Based Electronic Auditing Tool

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Macumber, Daniel; Parker, Andrew; Lisell, Lars

    2014-05-08

    'simuwatt Energy Auditor' (TM) is a new tablet-based electronic auditing tool that is designed to dramatically reduce the time and cost to perform investment-grade audits and improve quality and consistency. The tool uses the U.S. Department of Energy's OpenStudio modeling platform and integrated Building Component Library to automate modeling and analysis. simuwatt's software-guided workflow helps users gather required data, and provides the data in a standard electronic format that is automatically converted to a baseline OpenStudio model for energy analysis. The baseline energy model is calibrated against actual monthly energy use to ASHRAE Standard 14 guidelines. Energy conservation measures frommore » the Building Component Library are then evaluated using OpenStudio's parametric analysis capability. Automated reporting creates audit documents that describe recommended packages of energy conservation measures. The development of this tool was partially funded by the U.S. Department of Defense's Environmental Security Technology Certification Program. As part of this program, the tool is being tested at 13 buildings on 5 Department of Defense sites across the United States. Results of the first simuwatt audit tool demonstration are presented in this paper.« less

  14. If you can't take the room out of your mix, you can't take your mix out of the room!

    NASA Astrophysics Data System (ADS)

    D'Antonio, Peter

    2003-04-01

    The key issue in any recording studio is transferability-the ability of a mix to transfer to other listening environments outside the studio. For a mix to faithfully transfer to a wide range of acoustical environments, it must be created in a room with minimal acoustic distortion. The music industry is very aware of electronic distortion; however, the audible effects of acoustic distortion are only now being fully appreciated. The four forms of acoustic distortion are modal coupling, speaker boundary interference response, comb filtering and poor diffusion or a sparse spatial and temporal reflection density. These phenomena will be explained and methods to minimize them will be suggested.

  15. KSC-02pd0119

    NASA Image and Video Library

    2002-02-11

    KENNEDY SPACE CENTER, FLA. -- Center Director Roy Bridges Jr. (center) cuts the ribbon for the opening of KSC Direct, the new Web-Broadcast Studio at KSC. Joining him are (left to right) Dennis Armstrong, Web Multimedia manager; JoAnn H. Morgan, director of External Relations and Business Development; Bridges; Vanessa Stromer, Information Technology Division, Spaceport Services; and Brian Chase, district director for Congressman Dave Weldon, who was unable to attend the ceremony. Located in the News Center on the Press Mound at KSC, the Web Broadcast Studio provides video clips of launches, landings and other KSC events in a real-time environment, called KSC Direct, through KSC's Web pages

  16. Parallel processing implementation for the coupled transport of photons and electrons using OpenMP

    NASA Astrophysics Data System (ADS)

    Doerner, Edgardo

    2016-05-01

    In this work the use of OpenMP to implement the parallel processing of the Monte Carlo (MC) simulation of the coupled transport for photons and electrons is presented. This implementation was carried out using a modified EGSnrc platform which enables the use of the Microsoft Visual Studio 2013 (VS2013) environment, together with the developing tools available in the Intel Parallel Studio XE 2015 (XE2015). The performance study of this new implementation was carried out in a desktop PC with a multi-core CPU, taking as a reference the performance of the original platform. The results were satisfactory, both in terms of scalability as parallelization efficiency.

  17. Video distribution system cost model

    NASA Technical Reports Server (NTRS)

    Gershkoff, I.; Haspert, J. K.; Morgenstern, B.

    1980-01-01

    A cost model that can be used to systematically identify the costs of procuring and operating satellite linked communications systems is described. The user defines a network configuration by specifying the location of each participating site, the interconnection requirements, and the transmission paths available for the uplink (studio to satellite), downlink (satellite to audience), and voice talkback (between audience and studio) segments of the network. The model uses this information to calculate the least expensive signal distribution path for each participating site. Cost estimates are broken downy by capital, installation, lease, operations and maintenance. The design of the model permits flexibility in specifying network and cost structure.

  18. [Trattamento farmacologico del disturbo da uso di alcol. Evidenze scientifiche].

    PubMed

    Attilia, Fabio; Perciballi, Roberta; Rotondo, Claudia; Capriglione, Ida; Iannuzzi, Silvia; Attilia, Maria Luisa; Vitali, Mario; Alessandrini, Giovanni; Scamporrino, Maria Concetta Marcella; Fiore, Marco; Ceccanti, Mauro

    2018-01-01

    RIASSUNTO. La terapia farmacologica nei pazienti con disturbo da uso di alcol riveste un ruolo centrale nel progetto terapeutico, altamente contestualizzato in un approccio multidisciplinare. Sebbene i trattamenti non farmacologici per la dipendenza da alcol risultino ben strutturati e in continua evoluzione, dal punto di vista medico le possibilità di intervento sono realmente ristrette, con poche molecole a disposizione approvate per il disturbo da uso di alcol: nello specifico, l'acamprostato, il naltrexone e, più recentemente, il nalmefene tra gli anticraving; il disulfiram tra gli avversivanti. Nuovi approcci sperimentali stanno cercando di ampliare tale gamma attraverso l'utilizzo di farmaci off-label. Evidenze scientifiche devono supportare l'indicazione terapeutica, quest'ultima deve dimostrarsi "cucita" sulle esigenze del paziente e sulle comorbilità presenti tenendo conto del profilo bio-psico-sociale individuale. Fondamentale risulta il follow-up per valutare la ritenzione in trattamento e il monitoraggio degli outcome alcologici.

  19. System of indexes and indicators for the quality evaluation of HACCP plans based on the results of the official controls conducted by the Servizio di Igiene degli Alimenti della Nutrizione (Food and Nutrition Health Service) of the Local Health Authority of Foggia, Italy.

    PubMed

    Panunzio, Michele F; Antoniciello, Antonietta; Pisano, Alessandra

    2007-03-01

    Within the realm of evaluating self-monitoring plans, developed based on the Hazard Analysis and Critical Control Points (HACCP) method and adopted by food companies, little research has been done concerning the quality of the plans. The Servizio di Igiene degli Alimenti e della Nutrizione (Food and Nutrition Health Service) of the Local Health Authority of Foggia, Italy, has conducted research with the aim to adopt a system of indexes and indicators for the qualitative evaluation of HACCP plans. The critical areas considered were the following: simplicity, specificity, feasibility and adherence. During the period from January 2004 to June 2005, the evaluation grid was used in examining 250 HACCP self-monitoring plans of food companies. For the analysis of the determining factor four groups were considered, with reference to HACCP self-monitoring plans designed: group 1 - with the aid of a qualified team; group 2 - with the aid of an unqualified team; group 3 - with the aid of an unqualified expert; group 4 - without the aid of an expert. The mean values of the measures elaborated decrease towards insufficiency moving from group 1 to group 4. In particular, collaboration by teams of unqualified experts brought about drafting unacceptable HACCP plans on the levels of specificity and adherence, with respect to the HACCP method. The method proposed of the analysis of the indexes and indicators beginning with an evaluation sheet can also help the individual company to better adjust contribution by internal or external professionals to the company.

  20. The Italian Army and Effects-Based Operations: A New Concept for an Army of Use

    DTIC Science & Technology

    2005-05-25

    efficiently42. 41 Ministero della Difesa, Libro Bianco 2002 (Roma: Stabilimento Grafico Militare...GUARDIAN/. Internet; accessed 22 March 2006. __________. Libro Bianco 2002. Roma: Stabilimento grafico Militare, 2001. __________. Nuove Forze per un

  1. [Evaluation of mercury exposure in populations living near the industrial Augusta Bay (Sicily Region, Southern Italy)].

    PubMed

    Bonsignore, Maria; Andolfi, Nunzia; Quinci, Enza Maria; Madeddu, Anselmo; Tisano, Francesco; Ingallinella, Vincenzo; Castorina, Maria; Sprovieri, Mario

    2016-01-01

    OBIETTIVI: valutare e quantificare l'esposizione umana al mercurio (Hg) ed esplorare i fattori chiave che influenzano la contaminazione nelle popolazioni residenti in prossimità della Rada di Augusta, un'area a elevato rischio ambientale a causa degli effetti degli sversamenti incontrollati di Hg da parte di uno dei più grandi impianti cloro-soda d'Europa. DISEGNO: un campione di residenti nei comuni di Augusta, Priolo e Melilli (Sicilia orientale) è stato selezionato per lo studio di biomonitoraggio umano. Un questionario dettagliato è stato somministrato a ogni partecipante per raccogliere informazioni anagrafiche sulle abitudini di vita e alimentari. I livelli di Hg in sangue e capelli, usati come traccianti di esposizione a metilmercurio, sono stati messi in relazione al consumo di pesce locale. Il contenuto di Hg nelle urine è stato utilizzato per esplorare eventuali esposizioni atmosferiche a Hg inorganico. Una regressione lineare multivariata è stata applicata con l'obiettivo di esplorare i fattori che influenzano l'esposizione umana al Hg. L'approccio tossicocinetico è stato impiegato al fine di calcolare la dose settimanale provvisoria tollerabile ( provisional tolerable weekly intake, PTWI) e di predire le concentrazioni di Hg attese nel sangue degli individui con una dieta alimentare basata esclusivamente su pesce locale. 224 individui residenti nei comuni di Augusta, Melilli e Priolo. RISULTATI: eccessi di Hg sono stati misurati nel sangue e nei capelli del campione considerato. I più alti livelli sono stati rilevati ad Augusta, dove anche il consumo di pesce locale risulta maggiore. I valori di dose settimanale tollerabile provvisoria (PTWI) calcolati eccedono, nella maggior parte dei casi, le raccomandazioni internazionali, specialmente nei residenti ad Augusta. CONCLUSIONI: gli elevati livelli di Hg registrati nei campioni di sangue e capelli derivano, con ogni probabilità, dal consumo di pesce locale. Rispetto ad Augusta, gli individui di

  2. Il volto della Luna da Plutarco a Newton. Storia di una teoria ellenistica della gravità

    NASA Astrophysics Data System (ADS)

    Cappi, Alberto

    2013-03-01

    In his dialogue "De Facie quae in Orbe Lunae apparet", Plutarch includes a discussion on a non-Aristotelian theory of gravity. I describe how this theory could be developed during the Hellenistic period and its influence on the cosmological debate along the centuries until the beginning of modern science. (Text in Italian)

  3. Signed, sealed and delivered: “big tobacco” in Hollywood, 1927–1951

    PubMed Central

    Lum, K L; Polansky, J R; Jackler, R K; Glantz, S A

    2008-01-01

    Objective: Smoking in movies is associated with adolescent and young adult smoking initiation. Public health efforts to eliminate smoking from films accessible to youth have been countered by defenders of the status quo, who associate tobacco imagery in “classic” movies with artistry and nostalgia. The present work explores the mutually beneficial commercial collaborations between the tobacco companies and major motion picture studios from the late 1920s through the 1940s. Methods: Cigarette endorsement contracts with Hollywood stars and movie studios were obtained from internal tobacco industry documents at the University of California, San Francisco (UCSF) Legacy Tobacco Documents Library and the Jackler advertising collection at Stanford. Results: Cigarette advertising campaigns that included Hollywood endorsements appeared from 1927 to 1951, with major activity in 1931–2 and 1937–8 for American Tobacco Company’s Lucky Strike, and in the late 1940s for Liggett & Myers’ Chesterfield. Endorsement contracts and communication between American Tobacco and movie stars and studios explicitly reveal the cross-promotional value of the campaigns. American Tobacco paid movie stars who endorsed Lucky Strike cigarettes US$218 750 in 1937–8 (equivalent to US$3.2 million in 2008) for their testimonials. Conclusions: Hollywood endorsements in cigarette advertising afforded motion picture studios nationwide publicity supported by the tobacco industry’s multimillion US dollar advertising budgets. Cross-promotion was the incentive that led to a synergistic relationship between the US tobacco and motion picture industries, whose artefacts, including “classic” films with smoking and glamorous publicity images with cigarettes, continue to perpetuate public tolerance of onscreen smoking. Market-based disincentives within the film industry may be a solution to decouple the historical association between Hollywood films and cigarettes. PMID:18818225

  4. Flower opening and closure: an update.

    PubMed

    van Doorn, Wouter G; Kamdee, Chanattika

    2014-11-01

    This review is an update of a 2003 review (Journal of Experimental Botany 54,1801-1812) by the same corresponding author. Many examples of flower opening have been recorded using time-lapse photography, showing its velocity and the required elongation growth. Ethylene regulates flower opening, together with at least gibberellins and auxin. Ethylene and gibberellic acid often promote and inhibit, respectively, the expression of DELLA genes and the stability of DELLA proteins. DELLA results in growth inhibition. Both hormones also inhibited and promoted, respectively, the expression of aquaporin genes required for cell elongation. Arabidopsis miRNA319a mutants exhibited narrow and short petals, whereby miRNA319a indirectly regulates auxin effects. Flower opening in roses was controlled by a NAC transcription factor, acting through miRNA164. The regulatory role of light and temperature, in interaction with the circadian clock, has been further elucidated. The end of the life span in many flowers is determined by floral closure. In some species pollination resulted in earlier closure of turgid flowers, compared with unpollinated flowers. It is hypothesized that this pollination-induced effect is only found in flowers in which closure is regulated by ethylene. © The Author 2014. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  5. Investigation and Evaluation of the open source ETL tools GeoKettle and Talend Open Studio in terms of their ability to process spatial data

    NASA Astrophysics Data System (ADS)

    Kuhnert, Kristin; Quedenau, Jörn

    2016-04-01

    Integration and harmonization of large spatial data sets is not only since the introduction of the spatial data infrastructure INSPIRE a big issue. The process of extracting and combining spatial data from heterogeneous source formats, transforming that data to obtain the required quality for particular purposes and loading it into a data store, are common tasks. The procedure of Extraction, Transformation and Loading of data is called ETL process. Geographic Information Systems (GIS) can take over many of these tasks but often they are not suitable for processing large datasets. ETL tools can make the implementation and execution of ETL processes convenient and efficient. One reason for choosing ETL tools for data integration is that they ease maintenance because of a clear (graphical) presentation of the transformation steps. Developers and administrators are provided with tools for identification of errors, analyzing processing performance and managing the execution of ETL processes. Another benefit of ETL tools is that for most tasks no or only little scripting skills are required so that also researchers without programming background can easily work with it. Investigations on ETL tools for business approaches are available for a long time. However, little work has been published on the capabilities of those tools to handle spatial data. In this work, we review and compare the open source ETL tools GeoKettle and Talend Open Studio in terms of processing spatial data sets of different formats. For evaluation, ETL processes are performed with both software packages based on air quality data measured during the BÄRLIN2014 Campaign initiated by the Institute for Advanced Sustainability Studies (IASS). The aim of the BÄRLIN2014 Campaign is to better understand the sources and distribution of particulate matter in Berlin. The air quality data are available in heterogeneous formats because they were measured with different instruments. For further data analysis

  6. An Exploratory Study: Assessment of Modeled Dioxin ...

    EPA Pesticide Factsheets

    EPA announced the availability of the final report, An Exploratory Study: Assessment of Modeled Dioxin Exposure in Ceramic Art Studios. This report investigates the potential dioxin exposure to artists/hobbyists who use ball clay to make pottery and related products. Dermal, inhalation, and ingestion exposures to clay were measured at the ceramics art department of Ohio State University in Columbus, OH. The exposure estimates were based on measured levels of clay in the studio air, deposited on surrogate food samples and on the skin of the artists. The purpose of this report is to describe an exploratory investigation of potential dioxin exposures to artists/hobbyists who use ball clay to make pottery and related products.

  7. BeadArray Expression Analysis Using Bioconductor

    PubMed Central

    Ritchie, Matthew E.; Dunning, Mark J.; Smith, Mike L.; Shi, Wei; Lynch, Andy G.

    2011-01-01

    Illumina whole-genome expression BeadArrays are a popular choice in gene profiling studies. Aside from the vendor-provided software tools for analyzing BeadArray expression data (GenomeStudio/BeadStudio), there exists a comprehensive set of open-source analysis tools in the Bioconductor project, many of which have been tailored to exploit the unique properties of this platform. In this article, we explore a number of these software packages and demonstrate how to perform a complete analysis of BeadArray data in various formats. The key steps of importing data, performing quality assessments, preprocessing, and annotation in the common setting of assessing differential expression in designed experiments will be covered. PMID:22144879

  8. [Occupational exposure to airborne chemical substances in paintings conservators].

    PubMed

    Jezewska, Anna; Szewczyńska, Małgorzata; Woźnica, Agnieszka

    2014-01-01

    This paper presents the results of the quantitative study of the airborne chemical substances detected in the conservator's work environment. The quantitative tests were carried out in 6 museum easel paintings conservation studios. The air test samples were taken at various stages of restoration works, such as cleaning, doubling, impregnation, varnishing, retouching, just to name a few. The chemical substances in the sampled air were measured by the GC-FID (gas chromatography with flame ionization detector) test method. The study results demonstrated that concentrations of airborne substances, e.g., toluene, 1,4-dioxane, turpentine and white spirit in the work environment of paintings conservators exceeded the values allowed by hygiene standards. It was found that exposure levels to the same chemical agents, released during similar activities, varied for different paintings conservation studios. It is likely that this discrepancy resulted from the indoor air exchange system for a given studio (e.g. type of ventilation and its efficiency), the size of the object under maintenance, and also from the methodology and protection used by individual employees. The levels of organic solvent vapors, present in the workplace air in the course of painting conservation, were found to be well above the occupational exposure limits, thus posing a threat to the worker's health.

  9. The museum of unnatural form: a visual and tactile experience of fractals.

    PubMed

    Della-Bosca, D; Taylor, R P

    2009-01-01

    A remarkable computer technology is revolutionizing the world of design, allowing intricate patterns to be created with mathematical precision and then 'printed' as physical objects. Contour crafting is a fabrication process capable of assembling physical structures the sizes of houses, firing the imagination of a new generation of architects and artists (Khoshnevisat, 2008). Daniel Della-Bosca has jumped at this opportunity to create the 'Museum of Unnatural Form' at Griffith University. Della-Bosca's museum is populated with fractals sculptures - his own versions of nature's complex objects - that have been printed with the new technology. His sculptures bridge the historical divide in fractal studies between the abstract images of mathematics and the physical objects of Nature (Mandelbrot, 1982). Four of his fractal images will be featured on the cover of NDPLS in 2009.

  10. Higher Order Thinking in the Dance Studio

    ERIC Educational Resources Information Center

    Moffett, Ann-Thomas

    2012-01-01

    The author identifies higher order thinking as an essential component of dance training for students of all ages and abilities. Weaving together insights from interviews with experts in the field of dance education with practical pedagogical applications within an Improvisation and Composition class for talented and gifted youth, this article…

  11. Art and Technology: Computers in the Studio?

    ERIC Educational Resources Information Center

    Ruby-Baird, Janet

    1997-01-01

    Because the graphic industry demands graduates with computer skills, art students want college programs that include complex computer technologies. However, students can produce good computer art only if they have mastered traditional drawing and design skills. Discusses designing an art curriculum including both technology and traditional course…

  12. On-Line Critiques in Collaborative Design Studio

    ERIC Educational Resources Information Center

    Sagun, Aysu; Demirkan, Halime

    2009-01-01

    In this study, the Design Collaboration Model (DCM) was developed to provide a medium for the on-line collaboration of the design courses. The model was based on the situated and reflective practice characteristics of the design process. The segmentation method was used to analyse the design process observed both in the design diaries and the…

  13. 40 CFR Appendix L to Part 51 - Example Regulations for Prevention of Air Pollution Emergency Episodes

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... selling merchandise to such persons or companies, except those engaged in the distribution of drugs... studios; beauty shops, barber shops, shoe repair shops. i. Advertising offices; consumer credit reporting...

  14. 40 CFR Appendix L to Part 51 - Example Regulations for Prevention of Air Pollution Emergency Episodes

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... selling merchandise to such persons or companies, except those engaged in the distribution of drugs... studios; beauty shops, barber shops, shoe repair shops. i. Advertising offices; consumer credit reporting...

  15. 40 CFR Appendix L to Part 51 - Example Regulations for Prevention of Air Pollution Emergency Episodes

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... selling merchandise to such persons or companies, except those engaged in the distribution of drugs... studios; beauty shops, barber shops, shoe repair shops. i. Advertising offices; consumer credit reporting...

  16. 40 CFR Appendix L to Part 51 - Example Regulations for Prevention of Air Pollution Emergency Episodes

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... selling merchandise to such persons or companies, except those engaged in the distribution of drugs... studios; beauty shops, barber shops, shoe repair shops. i. Advertising offices; consumer credit reporting...

  17. 40 CFR Appendix L to Part 51 - Example Regulations for Prevention of Air Pollution Emergency Episodes

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... selling merchandise to such persons or companies, except those engaged in the distribution of drugs... studios; beauty shops, barber shops, shoe repair shops. i. Advertising offices; consumer credit reporting...

  18. Madonna della Pietá by Michelangelo.

    PubMed

    Wentz, Margaret R

    2018-05-01

    Recognizing the contribution art has had in the Mayo Clinic environment since the original Mayo Clinic Building was finished in 1914, Mayo Clinic Proceedings features some of the numerous works of art displayed throughout the buildings and grounds on Mayo Clinic campuses as interpreted by the author. Copyright © 2018 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Romanov, Gennady

    Typically the RFQs are designed using the Parmteq, DesRFQ and other similar specialized codes, which produces the files containing the field and geometrical parameters for every cell. The beam dynamic simulations with these analytical fields a re, of course, ideal realizations of the designed RFQs. The new advanced computing capabilities made it possible to simulate beam and even dark current in the realistic 3D electromagnetic fields in the RFQs that may reflect cavity tuning, presence of tune rs and couplers, RFQ segmentation etc. The paper describes the utilization of full 3D field distribution obtained with CST Studio Suite for beammore » dynamic simulations using both PIC solver of CST Particle Studio and the beam dynamic code TRACK.« less

  20. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kasemir, Kay; Pearson, Matthew R

    For several years, the Control System Studio (CS-Studio) Scan System has successfully automated the operation of beam lines at the Oak Ridge National Laboratory (ORNL) High Flux Isotope Reactor (HFIR) and Spallation Neutron Source (SNS). As it is applied to additional beam lines, we need to support simultaneous adjustments of temperatures or motor positions. While this can be implemented via virtual motors or similar logic inside the Experimental Physics and Industrial Control System (EPICS) Input/Output Controllers (IOCs), doing so requires a priori knowledge of experimenters requirements. By adding support for the parallel control of multiple process variables (PVs) to themore » Scan System, we can better support ad hoc automation of experiments that benefit from such simultaneous PV adjustments.« less

  1. FROMS3D: New Software for 3-D Visualization of Fracture Network System in Fractured Rock Masses

    NASA Astrophysics Data System (ADS)

    Noh, Y. H.; Um, J. G.; Choi, Y.

    2014-12-01

    A new software (FROMS3D) is presented to visualize fracture network system in 3-D. The software consists of several modules that play roles in management of borehole and field fracture data, fracture network modelling, visualization of fracture geometry in 3-D and calculation and visualization of intersections and equivalent pipes between fractures. Intel Parallel Studio XE 2013, Visual Studio.NET 2010 and the open source VTK library were utilized as development tools to efficiently implement the modules and the graphical user interface of the software. The results have suggested that the developed software is effective in visualizing 3-D fracture network system, and can provide useful information to tackle the engineering geological problems related to strength, deformability and hydraulic behaviors of the fractured rock masses.

  2. 77 FR 54604 - Endangered Species; Receipt of Applications for Permit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... your request for copies of applications or comments and materials concerning any of the applications to.... Permit Applications A. Endangered Species Applicant: Big Game Studio, Bronte, TX; PRT-82880A The...

  3. 26. Photocopy of photograph (original print in files of Milton ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. Photocopy of photograph (original print in files of Milton T. Pflueger, AIA) Gabriel Moulin Studios, Photographer 1932 WOMEN'S SMOKING ROOM IN BASEMENT - Paramount Theatre, 2025 Broadway, Oakland, Alameda County, CA

  4. 29. Photocopy of photograph (original print in files of Milton ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    29. Photocopy of photograph (original print in files of Milton T. Pflueger, AIA) Gabriel Moulin Studios, Photographer 1932 COSMETIC ROOM, WOMEN'S MEZZANINE LOUNGE - Paramount Theatre, 2025 Broadway, Oakland, Alameda County, CA

  5. [Pietro d'Abano and the astrological and scientific image in Padova during the XIV century: from Giotto to Carraresi].

    PubMed

    Mariani Canova, Giordana

    2008-01-01

    The paper intends to prove the incidence that scientific doctrines, mostly Pietro d'Abano's astrological and medical studies, had on Giotto's painting at the Cappella degli Scrovegni in Padova and his lost astrological cycle in the Sala della Ragione. It is emphasized how in no other painting of his, Giotto displayed as much intellectualism as in the Cappella degli Scrovegni. There we can note the importance of the physical representation of the sky and stars and figures' particular physiognomic characterization referable to Pietro d'Abano's theories presented in his astrological treatises and in his Compilation Phisionomiae. Even the ecceptional botanical realism displayed in the representation of plants can be probably referred to Pietro d'Abano's scientific teaching. An hypotetical reconstruction, according to Ptolomeus' theories and Pietro d'Abano's physiognomic, of Giotto's astrological cycle in the Sala della Ragione is also proposed.

  6. 22 CFR Appendix C to Part 513 - Certification Regarding Drug-Free Workplace Requirements

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... is providing the certification set out below. 2. The certification set out below is a material... employees in each local unemployment office, performers in concert halls or radio studios). 7. If the...

  7. 29 CFR 793.3 - Statutory provision.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... employed as an announcer, news editor, or chief engineer by a radio or television station the major studio... INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS EXEMPTION OF CERTAIN RADIO AND TELEVISION STATION EMPLOYEES...

  8. Age 60 study, part III : consolidated database experiments final report.

    DOT National Transportation Integrated Search

    1994-10-01

    This document is one of four products completed as a part of the Age 60 Rule research contract monitored by Pam Della Rocco, Civil Aerospace Medical Institute, Contracting Officer's Technical Representative. This work was performed. This report was a...

  9. 29 CFR 793.7 - “Announcer.”

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... time signals, and present other similar routine on-the-air material. In small stations, an announcer may, in addition to these duties, operate the studio control board, give cues to the control room for...

  10. What Is Hot Yoga (Bikram)?

    MedlinePlus

    ... a vigorous form of yoga performed in a studio that is heated to 105 F (40 C) ... opportunities Reprint Permissions A single copy of these materials may be reprinted for noncommercial personal use only. " ...

  11. 29 CFR 793.7 - “Announcer.”

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... time signals, and present other similar routine on-the-air material. In small stations, an announcer may, in addition to these duties, operate the studio control board, give cues to the control room for...

  12. 29 CFR 793.7 - “Announcer.”

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... time signals, and present other similar routine on-the-air material. In small stations, an announcer may, in addition to these duties, operate the studio control board, give cues to the control room for...

  13. KENNEDY SPACE CENTER, FLA. -- KSC management and other employees gather in the Center’s television studio to watch the address by President George W. Bush at NASA Headquarters in Washington, D.C., stating his goals for NASA’s new mission: Completing the International Space Station, retiring the Space Shuttle orbiters, developing a new crew exploration vehicle, and returning to the moon and beyond within the next two decades. Pres. Bush was welcomed by NASA Administrator Sean O’Keefe and Expedition 8 Commander Michael Foale, who greeted him from the International Space Station. Members of the Washington, D.C., audience included astronauts Eileen Collins, Ed Lu and Michael Lopez-Alegria, and former astronaut Gene Cernan.

    NASA Image and Video Library

    2004-01-14

    KENNEDY SPACE CENTER, FLA. -- KSC management and other employees gather in the Center’s television studio to watch the address by President George W. Bush at NASA Headquarters in Washington, D.C., stating his goals for NASA’s new mission: Completing the International Space Station, retiring the Space Shuttle orbiters, developing a new crew exploration vehicle, and returning to the moon and beyond within the next two decades. Pres. Bush was welcomed by NASA Administrator Sean O’Keefe and Expedition 8 Commander Michael Foale, who greeted him from the International Space Station. Members of the Washington, D.C., audience included astronauts Eileen Collins, Ed Lu and Michael Lopez-Alegria, and former astronaut Gene Cernan.

  14. KENNEDY SPACE CENTER, FLA. - Standing inside Discovery’s payload bay, Carol Scott (right), lead orbiter engineer, talks about her job as part of a special feature for the KSC Web. With his back to the camera is Bill Kallus, Media manager in the KSC Web Studio. Behind Scott can be seen the open hatch of the airlock, which provides support functions such as airlock depressurization and repressurization, extravehicular activity equipment recharge, liquid-cooled garment water cooling, EVA equipment checkout, donning and communications. The outer hatch isolates the airlock from the unpressurized payload bay when closed and permits the EVA crew members to exit from the airlock to the payload bay when open.

    NASA Image and Video Library

    2004-01-22

    KENNEDY SPACE CENTER, FLA. - Standing inside Discovery’s payload bay, Carol Scott (right), lead orbiter engineer, talks about her job as part of a special feature for the KSC Web. With his back to the camera is Bill Kallus, Media manager in the KSC Web Studio. Behind Scott can be seen the open hatch of the airlock, which provides support functions such as airlock depressurization and repressurization, extravehicular activity equipment recharge, liquid-cooled garment water cooling, EVA equipment checkout, donning and communications. The outer hatch isolates the airlock from the unpressurized payload bay when closed and permits the EVA crew members to exit from the airlock to the payload bay when open.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    K. Gering

    An important feature of the DUALFOIL model for simulation of lithium-ion cells [1,2] is rigorous accounting for non-ideal electrolyte properties. Unfortunately, data are available on only a few electrolytes [3,4]. However, K. Gering has developed a model for estimation of electrolyte properties [5] and recently generated complete property sets (density, conductivity, activity coefficient, diffusivity, transport number) as a function of temperature and salt concentration. Here we use these properties in an enhanced version of the DUALFOIL model called DISTNP, available in Battery Design Studio [6], to examine the effect of different electrolytes on cell performance. Specifically, the behavior of amore » high energy LiCoO2/graphite 18650-size cell is simulated. The ability of Battery Design Studio to si« less

  16. Highlight summarization in golf videos using audio signals

    NASA Astrophysics Data System (ADS)

    Kim, Hyoung-Gook; Kim, Jin Young

    2008-01-01

    In this paper, we present an automatic summarization of highlights in golf videos based on audio information alone without video information. The proposed highlight summarization system is carried out based on semantic audio segmentation and detection on action units from audio signals. Studio speech, field speech, music, and applause are segmented by means of sound classification. Swing is detected by the methods of impulse onset detection. Sounds like swing and applause form a complete action unit, while studio speech and music parts are used to anchor the program structure. With the advantage of highly precise detection of applause, highlights are extracted effectively. Our experimental results obtain high classification precision on 18 golf games. It proves that the proposed system is very effective and computationally efficient to apply the technology to embedded consumer electronic devices.

  17. Deep and Broad are the Laws of Emergence?

    NASA Astrophysics Data System (ADS)

    Sgorbati, Susan; Weber, Bruce

    Bruce Weber, evolutionary biologist and Susan Sgorbati, choreographer have been in a dialogue for the last several years asking the question of whether there are deep structuring principles that cross disciplines. While both professors at Bennington College, they developed a series of courses that explored these structuring principles in complex systems. Ideas such as self-organization, emergence, improvisation, and complexity were investigated through the lens of different disciplines and modes of perception. The inquiry was both intellectually driven and experientially driven. Students were asked to research and write papers, as well as move in the dance studio. Experiments in the studio led Susan Sgorbati to develop research that subsequently resulted in a national tour with professional dancers and musicians who are participating in a performance as part of this conference.

  18. Il problema della scelta e della continuita della lingua straniera nella scuola dell'obbligo (Problems of Choice and Continuity of a Foreign Language in Elementary and Junior High School).

    ERIC Educational Resources Information Center

    Gotti, Maurizio

    1987-01-01

    Discusses two current problems with foreign language study in Italy: (1) Students are frequently unable to study English, the most popular language, because of a lack of qualified English teachers; and (2) Students sometimes cannot continue studying in junior high school the language they began in elementary school. (CFM)

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Walker, La Tonya; Malczynski, Leonard

    A Powersim Studio implementation of the system dynamics’ ‘Molecules of Structure’. The original implementation was in Ventana’s Vensim language by James Hines. The molecules are fundamental constructs of the system dynamics simulation methodology.

  20. 78 FR 66783 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ... appropriate, to the determination of the date on which total or partial separations began or threatened to... Pigments USA Inc. Fall River, MA........ 09/23/13 09/20/13 (Company). 83104 Rhythm & Hues Studios El...

  1. Kyle Benne | NREL

    Science.gov Websites

    developer. He is a member of the OpenStudio development team, where he focuses on creating new simulation expertise in fluid mechanics and numerical simulation. Education M.S. Mechanical Engineering, Missouri

  2. Age 60 study, part IV : experimental evaluation of pilot performance.

    DOT National Transportation Integrated Search

    1994-10-01

    This document is one of four products completed as a part of the Age 60 Rule Research Contract monitored by Pam Della Rocco, Civil Aerospace Medical Institute. This report was a deliverable from the research contract with Hilton Systems, Inc. on the ...

  3. Galileo's Lens

    NASA Astrophysics Data System (ADS)

    Manos, Harry

    2003-05-01

    Most visitors to Florence, Italy, know about the Galleria dell'Accademia, housing Michelangelo's famous statue of David, or the Galleria degli Uffizi with the famous Medici collection. Few visitors know that only two blocks from the Uffizi on the Arno River is one of the world's finest museums featuring historic scientific instruments, the Museo di Storia della Scienza. In the February issue of TPT, Nickell states that the Museo di Storia della Scienza ``is perhaps the best museum on the history of science in the world.''1 This fact is likely true, and the museum is a must for physics teachers visiting Florence. It features a vast collection of authentic ``cutting-edge'' scientific instruments, including one of Galileo's lenses in a magnificent ebony and ivory frame. One of the tragedies is that this museum goes unmarked on many tourist maps and unmentioned in many guidebooks.

  4. Helminthosporic acid functions as an agonist for gibberellin receptor.

    PubMed

    Miyazaki, Sho; Jiang, Kai; Kobayashi, Masatomo; Asami, Tadao; Nakajima, Masatoshi

    2017-11-01

    Helminthosporol was isolated from a fungus, Helminthosporium sativum, as a natural plant growth regulator in 1963. It showed gibberellin-like bioactivity that stimulated the growth of the second leaf sheath of rice. After studying the structure-activity relationship between the compound and some synthesized analogs, it was found that helminthosporic acid (H-acid) has higher gibberellin-like activity and chemical stability than helminthosporol. In this study, we showed that (1) H-acid displays gibberellin-like activities not only in rice but also in Arabidopsis, (2) it regulates the expression of gibberellin-related genes, (3) it induces DELLA degradation through binding with a gibberellin receptor (GID1), and (4) it forms the GID1-(H-acid)-DELLA complex to transduce the gibberellin signal in the same manner as gibberellin. This work shows that the H-acid mode of action acts as an agonist for gibberellin receptor.

  5. Aortopexy for the treatment of tracheomalacia in children: review of the literature

    PubMed Central

    2012-01-01

    delicate is represented by those with associated gastro-esophageal reflux, in whom a fundoplication should be performed. Other treatments of tracheomalacia, particularly tracheal stenting, were associated with a higher rate of failure, severe morbidity and mortality. Non english abstract La tracheomalacia severa rappresenta una sfida per Pediatri, Intensivisti, Pneumologi, Otorinolaringoiatri, Chirurghi Pediatri. Il trattamento della tracheomalacia è tuttora controverso. L’aortopessi è considerata da molti la migliore opzione terapeutica. Abbiamo condotto una revisione della letteratura di lingua inglese su tale argomento. Di 125 lavori, 40 sono stati inclusi nella revisione. Tra 758 pazienti (62% maschi) affetti da tracheomalacia, 581 sono stati sottoposti ad aortopessi tra il 1968 e il 2008. In 659 pazienti alcune comorbidità erano presenti. L’associazione più frequente era con l’atresia esofagea (44%), l’anello vascolare o un’anomalia dei grossi vasi (18%), la compressione da parte dell’arteria innominata (16%); nel 9% la tracheomalacia era idiopatica. I sintomi riportati sono stati variabili, ma l’indicazione più importante all’aortopessi sono stati eventi di ALTE, osservati nel 43% dei pazienti. Lo studio diagnostico preoperatorio principale è stato la broncoscopia. L’approccio chirurgico è avvenuto attraverso una toracotomia anteriore sinistra nel 72% dei pazienti, mentre un approccio mediano è stato scelto nel 14% e nell’1.3% dei casi è stato eseguito un approccio toracoscopico. Al follow-up (mediana di 47 mesi) la maggioranza dei pazienti sono migliorati significativamente, ma l’8% di essi non è migliorato, il 4% è peggiorato e il 6% è morto. Complicazioni sono state riportate nel 15% dei pazienti, nell’1% un nuovo intervento di aortopessi è stato necessario. In questa revisione abbiamo trovato che non c’è un consenso generale sulla valutazione e sulla descrizione dei sintomi, sulle indicazioni chirurgiche ed esami

  6. 46 CFR 129.410 - Lighting fixtures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... fixture must have a high-strength guard or be made of high-strength material, except in accommodations... Studio Lighting Units,” or UL 1574, “Track Lighting Systems,” as long as the general marine requirements...

  7. 46 CFR 129.410 - Lighting fixtures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... fixture must have a high-strength guard or be made of high-strength material, except in accommodations... Studio Lighting Units,” or UL 1574, “Track Lighting Systems,” as long as the general marine requirements...

  8. 46 CFR 129.410 - Lighting fixtures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... fixture must have a high-strength guard or be made of high-strength material, except in accommodations... Studio Lighting Units,” or UL 1574, “Track Lighting Systems,” as long as the general marine requirements...

  9. 46 CFR 129.410 - Lighting fixtures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... fixture must have a high-strength guard or be made of high-strength material, except in accommodations... Studio Lighting Units,” or UL 1574, “Track Lighting Systems,” as long as the general marine requirements...

  10. Ad Layout Students Become "Artists" with Viewer Device

    ERIC Educational Resources Information Center

    Engel, Jack

    1977-01-01

    Suggests that the use of a projection viewer employed by professional art studios to make revised enlargements or reductions of existing art can improve the appearance of layouts done by creative, but artistically unskilled, students. (KS)

  11. Arabidopsis NAC Transcription Factor JUNGBRUNNEN1 Exerts Conserved Control Over Gibberellin and Brassinosteroid Metabolism and Signaling Genes in Tomato

    PubMed Central

    Shahnejat-Bushehri, Sara; Allu, Annapurna D.; Mehterov, Nikolay; Thirumalaikumar, Venkatesh P.; Alseekh, Saleh; Fernie, Alisdair R.; Mueller-Roeber, Bernd; Balazadeh, Salma

    2017-01-01

    The Arabidopsis thaliana NAC transcription factor JUNGBRUNNEN1 (AtJUB1) regulates growth by directly repressing GA3ox1 and DWF4, two key genes involved in gibberellin (GA) and brassinosteroid (BR) biosynthesis, respectively, leading to GA and BR deficiency phenotypes. AtJUB1 also reduces the expression of PIF4, a bHLH transcription factor that positively controls cell elongation, while it stimulates the expression of DELLA genes, which are important repressors of growth. Here, we extend our previous findings by demonstrating that AtJUB1 induces similar GA and BR deficiency phenotypes and changes in gene expression when overexpressed in tomato (Solanum lycopersicum). Importantly, and in accordance with the growth phenotypes observed, AtJUB1 inhibits the expression of growth-supporting genes, namely the tomato orthologs of GA3ox1, DWF4 and PIF4, but activates the expression of DELLA orthologs, by directly binding to their promoters. Overexpression of AtJUB1 in tomato delays fruit ripening, which is accompanied by reduced expression of several ripening-related genes, and leads to an increase in the levels of various amino acids (mostly proline, β-alanine, and phenylalanine), γ-aminobutyric acid (GABA), and major organic acids including glutamic acid and aspartic acid. The fact that AtJUB1 exerts an inhibitory effect on the GA/BR biosynthesis and PIF4 genes but acts as a direct activator of DELLA genes in both, Arabidopsis and tomato, strongly supports the model that the molecular constituents of the JUNGBRUNNEN1 growth control module are considerably conserved across species. PMID:28326087

  12. Characterization of the molecular mechanism underlying gibberellin perception complex formation in rice.

    PubMed

    Hirano, Ko; Asano, Kenji; Tsuji, Hiroyuki; Kawamura, Mayuko; Mori, Hitoshi; Kitano, Hidemi; Ueguchi-Tanaka, Miyako; Matsuoka, Makoto

    2010-08-01

    The DELLA protein SLENDER RICE1 (SLR1) is a repressor of gibberellin (GA) signaling in rice (Oryza sativa), and most of the GA-associated responses are induced upon SLR1 degradation. It is assumed that interaction between GIBBERELLIN INSENSITIVE DWARF1 (GID1) and the N-terminal DELLA/TVHYNP motif of SLR1 triggers F-box protein GID2-mediated SLR1 degradation. We identified a semidominant dwarf mutant, Slr1-d4, which contains a mutation in the region encoding the C-terminal GRAS domain of SLR1 (SLR1(G576V)). The GA-dependent degradation of SLR1(G576V) was reduced in Slr1-d4, and compared with SLR1, SLR1(G576V) showed reduced interaction with GID1 and almost none with GID2 when tested in yeast cells. Surface plasmon resonance of GID1-SLR1 and GID1-SLR1(G576V) interactions revealed that the GRAS domain of SLR1 functions to stabilize the GID1-SLR1 interaction by reducing its dissociation rate and that the G576V substitution in SLR1 diminishes this stability. These results suggest that the stable interaction of GID1-SLR1 through the GRAS domain is essential for the recognition of SLR1 by GID2. We propose that when the DELLA/TVHYNP motif of SLR1 binds with GID1, it enables the GRAS domain of SLR1 to interact with GID1 and that the stable GID1-SLR1 complex is efficiently recognized by GID2.

  13. Characterization of the Molecular Mechanism Underlying Gibberellin Perception Complex Formation in Rice[C][W

    PubMed Central

    Hirano, Ko; Asano, Kenji; Tsuji, Hiroyuki; Kawamura, Mayuko; Mori, Hitoshi; Kitano, Hidemi; Ueguchi-Tanaka, Miyako; Matsuoka, Makoto

    2010-01-01

    The DELLA protein SLENDER RICE1 (SLR1) is a repressor of gibberellin (GA) signaling in rice (Oryza sativa), and most of the GA-associated responses are induced upon SLR1 degradation. It is assumed that interaction between GIBBERELLIN INSENSITIVE DWARF1 (GID1) and the N-terminal DELLA/TVHYNP motif of SLR1 triggers F-box protein GID2-mediated SLR1 degradation. We identified a semidominant dwarf mutant, Slr1-d4, which contains a mutation in the region encoding the C-terminal GRAS domain of SLR1 (SLR1G576V). The GA-dependent degradation of SLR1G576V was reduced in Slr1-d4, and compared with SLR1, SLR1G576V showed reduced interaction with GID1 and almost none with GID2 when tested in yeast cells. Surface plasmon resonance of GID1-SLR1 and GID1-SLR1G576V interactions revealed that the GRAS domain of SLR1 functions to stabilize the GID1-SLR1 interaction by reducing its dissociation rate and that the G576V substitution in SLR1 diminishes this stability. These results suggest that the stable interaction of GID1-SLR1 through the GRAS domain is essential for the recognition of SLR1 by GID2. We propose that when the DELLA/TVHYNP motif of SLR1 binds with GID1, it enables the GRAS domain of SLR1 to interact with GID1 and that the stable GID1-SLR1 complex is efficiently recognized by GID2. PMID:20716699

  14. Anthony D. Fontanini | NREL

    Science.gov Websites

    simulation component models within EnergyPlus and OpenStudio. Prior to working at NREL, Anthony was a member building envelope and developed attic and roof simulation tools. His background is in modeling heat

  15. Age 60 rule research, part I : bibliographic database.

    DOT National Transportation Integrated Search

    1994-10-01

    This document is one of four products completed as a part of the Age 60 Rule research contract monitored by Pam Della Rocco, Civil Aerospace Medical Institute. As part of their research contract with the FAA to study issues related to the "Age 60 Rul...

  16. Interdisciplinary Co-operation (Part II of "Language Learning: Individual Needs, Interdisciplinary Co-operation, Bi- and Multilingualism").

    ERIC Educational Resources Information Center

    1978

    The following papers on interdisciplinary cooperation in second language instruction are included: (1) "Language Teaching: Possibilities for Interdisciplinary Co-operation," by James E. Alatis; (2) "L'insegnamento della letteratura italiana (The Teaching of Italian Literature)," by Ezio Raimondi; (3) "Objective Evaluation and Transparency," by…

  17. Slanting Design: A Pilot Program

    DTIC Science & Technology

    1985-10-01

    adequate financing and proper planning and forethought. itG’ven the significant number of variables over which FEMA has no control , however, it would...Eskilstuna SWEDEN Ministero dell Interno Direzione Generale della Protezione Civile 00100 Rome ITALY Directeur de la Protection: Civile Ministere de

  18. The Amsterdam model for control of tattoo parlours and businesses.

    PubMed

    Veenstra, Thijs

    2015-01-01

    In the early 1980s, an outbreak of hepatitis B in Amsterdam stood at the start of the development of the first hygiene guidelines for tattooists in The Netherlands. Ever since, infection control in tattoo practice has continued to prove its importance as tattoo-related outbreaks of infectious diseases have continued to be reported in Europe. Furthermore, the act of tattooing includes breaking the skin barrier but is performed by professionals who are not medically trained. The Ministry of Health has now implemented uniform regulations that apply to professionals who perform tattooing and apply permanent make-up. These regulations include hygiene guidelines that were developed by the National Institute for Public Health and the Environment in cooperation with representatives of the tattooing associations. The guidelines contain a list of requirements, including for the studio interior, the cleanness of the studio, the safe use of permitted equipment and products, sterilization methods, and the information provided to the customer. A permit may be granted after an inspection by the local health service, during which the act of tattooing has to be performed. It is now estimated that over 95% of all tattoos in The Netherlands were obtained at one of the almost 900 licensed studios. Reports of complications are generally low in number. We suggest that uniform European hygiene guidelines would further contribute to the safety of tattooing. © 2015 S. Karger AG, Basel.

  19. Design Process-System and Methodology of Design Research

    NASA Astrophysics Data System (ADS)

    Bashier, Fathi

    2017-10-01

    Studies have recognized the failure of the traditional design approach both in practice and in the studio. They showed that design problems today are too complex for the traditional approach to cope with and reflected a new interest in a better quality design services in order to meet the challenges of our time. In the mid-1970s and early 1980s, there has been a significant shift in focus within the field of design research towards the aim of creating a ‘design discipline’. The problem, as will be discussed, is the lack of an integrated theory of design knowledge that can explicitly describe the design process in a coherent way. As a consequence, the traditional approach fails to operate systematically, in a disciplinary manner. Addressing this problem is the primary goal of the research study in the design process currently being conducted in the research-based master studio at Wollega University, Ethiopia. The research study seeks to make a contribution towards a disciplinary approach, through proper understanding the mechanism of knowledge development within design process systems. This is the task of the ‘theory of design knowledge’. In this article the research project is introduced, and a model of the design process-system is developed in the studio as a research plan and a tool of design research at the same time. Based on data drawn from students’ research projects, the theory of design knowledge is developed and empirically verified through the research project.

  20. Controlling Asthma New Guidelines. New Medications. New Action Plans.

    MedlinePlus

    ... version of this page please turn Javascript on. New Guidelines. New Medications. New Action Plans. People everywhere and in every age ... I am putting the finishing touches on my new studio album that we hope to have out ...