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Sample records for neutral wind structures

  1. Thermal structure of neutral winds from young stellar objects

    NASA Technical Reports Server (NTRS)

    Ruden, Steven P.; Glassgold, Alfred E.; Shu, Frank H.

    1990-01-01

    The physical processes that control the thermal structure of lightly ionized winds from cool protostars are discussed. Attention is concentrated on the hydrogen gas, and the heating, cooling, and chemical processes that affect the neutral and ionic species of atomic and molecular hydrogen are examined. Warm silicate dust may condense out of the cooling wind and may heat the gas through collisions. Singly ionized sodium atoms, which do not recombine for the mass-loss rates considered, set a lower limit to the ionization fraction in the wind. Magnetic fields, which are presumed to accelerate the wind, couple directly to the ionic component of the gas and transfer momentum and energy to the neutral component through collisions. This process of ambipolar diffusion is found to be the dominant source of heat input to the gas.

  2. Equivalent Neutral Wind

    NASA Technical Reports Server (NTRS)

    Liu, W. Timothy; Tang, Wenqing

    1996-01-01

    The definition of equivalent neutral wind and the rationale for using it as the geophysical product of a spaceborne scatterometer are reviewed. The differences between equivalent neutral wind and actual wind, which are caused by atmospheric density stratification, are demonstrated with measurements at selected locations. A method of computing this parameter from ship and buoy measurements is described and some common fallacies in accounting for the effects of atmospheric stratification on wind shear are discussed. The computer code for the model to derive equivalent neutral wind is provided.

  3. Neutral Wind Observations below 200 km altitudes

    NASA Astrophysics Data System (ADS)

    Watanabe, S.; Abe, T.; Habu, H.; Kakinami, Y.; Larsen, M. F.; Pfaff, R. F., Jr.; Yamamoto, M.

    2015-12-01

    Neutral Wind Observations below 200 km altitudesS. Watanabe1, T. Abe2, H. Habu2, Y. Kakinami3, M. Larsen4, R. Pfaff5, M. Yamamoto6, M-Y. Yamamoto31Hokkaido University/Hokkaido Information University, 2JAXA/ISAS, 3Kochi University of Technology, 4Clemson University, 5NASA/Goddard Space Flight Center, 6Kyoto University, Neutral wind in the thermosphere is one of the key parameters to understand the ionosphere-thermosphere coupling process. JAXA/ISAS successfully launched sounding rockets from Uchinoura Space Center (USC) on September 2, 2007, January 12, 2012, and July 20, 2013, and NASA launched sounding rockets from Kwajalein on May 7, 2013 and from Wallops on July 4, 2013. The rockets installed Lithium and/or TMA canisters as well as instruments for plasma and electric and magnetic fields. The atomic Lithium gases were released at altitudes between 150 km and 300 km in the evening on September 2, 2007, at altitude of ~100 km in the morning on January 12, 2012, at altitude of ~120km in the midnight on July 20, 2013, at altitude between 150 km and 300 km in the evening on May 7, 2013 and at altitude of ~150 km in the noon on July 4, 2013. The Lithium atoms were scattering sunlight by resonance scattering with wavelength of 670nm. However, the Lithium atoms scattered moon light on July 20, 2013. The moon light scattering is the first time to use for thermospheric wind measurement in the midnight. The Lithium clouds/trails and TMA trails showed clearly the neutral wind shears and atmospheric waves at ~150 km altitude in the lower thermosphere for all local time.

  4. Processes of Neutral Winds in the Jovian Thermospehere

    NASA Astrophysics Data System (ADS)

    Majeed, T.; Waite, J. H.; Bougher, S. W.; Gladstone, G. R.; Bell, J.

    2012-09-01

    Recent analysis of high-resolution infrared spectroscopy of the Jovian aurora indicates the presence of highspeed neutral winds in Jupiter's thermosphere. While existing 1-D models are useful for understanding global averages of the Jovian thermosphere, 3-D models can provide significant insight into the regional importance of various dynamical processes. We use our fully coupled 3-D Jupiter Thermosphere General Circulation Model (JTGCM) to quantify wind processes that are responsible for generating neutral winds in the auroral thermosphere from 20 μbar to 10-4 nbar self-consistently with the thermal structure and compositions (ion and neutral). The heat sources in the JTGCM that drive the global neutral flow are high-latitude joule heating, resulting from frictional motion of ions relative to neutrals, and charge particle heating from auroral particle impact. These sources of high-latitude heating in the JTGCM are strongly related to the current system in the outer magnetosphere that allows plasma to flow in and out of the Jovian ionosphere. Due to Jupiter's rapid rotation, the mapping of this flow at ionospheric heights gives rise to an ion drag process in addition to Coriolis torque that appears to dominate the neutral momentum forcing near the altitude of the ionospheric peak. We find that for a rapidly rotating Jupiter, ion drag and joule heating inputs in the JTGCM significantly intensify the underlying global thermospheric dynamics and develop strong pressure gradients in the auroral oval regions, thereby affecting zonal and meridional winds. The zonal flow of neutral winds in the auroral ovals of both hemispheres is primarily driven by competition between the magnitudes of accelerations resulting from Coriolis forcing and ion drag processes near the ionospheric peak. However, above the ionospheric peak (<0.01 μbar), the acceleration of neutral flow due to pressure gradients in the upper thermosphere is found to be the most effective source of zonal winds

  5. Neutral solar wind evolution during solar cycle

    NASA Technical Reports Server (NTRS)

    Bzowski, M.; Rucinski, D.

    1995-01-01

    The time dependent model of the expected fluxes of the neutral H and He components of the solar wind in the inner heliosphere is discussed. The model takes into account typical temporal evolution of the distribution of neutral interstellar gases (hydrogen and helium) in the interplanetary space due to solar cycle effects and the long term variability of the solar wind. The contribution of different charge exchange processes to the production of particular NSW element is presented. The distribution of the NSW flux is analysed with respect to the heliocentric distance and azimuthal angle from the Interstellar Wind apex. It demonstrates significant, time-dependent upwind/downwind H and He flux asymmentries. It is shown that the most pronounced modulation of the NSW flux is expected around the solar maximum epoch, when a strong decrease of the energetic H flux by two three orders of magnitude at 1 AU is predicted. The computations show that in the inner solar system (approx. 1 AU) energetic helium atoms production in the downwind region usually dominates the production of the hydrogen component This leads to the conclusion that the NSW composition at the Earth orbit strongly depends on time and the position of the observation point in reference to the apex direction.

  6. Feedback between neutral winds and auroral arc electrodynamics

    NASA Technical Reports Server (NTRS)

    Lyons, L. R.; Walterscheid, R. L.

    1986-01-01

    The feedback between neutral atmospheric winds and the electrodynamics of a stable, discrete auroral arc is analyzed. The ionospheric current continuity equation and the equation for neutral gas acceleration by ion drag are solved simultaneously, as a function of time. The results show that, in general, the electric field in the ionosphere adjusts to neutral wind acceleration so as to keep auroral field-aligned currents and electron acceleration approximately independent of time. It is thus concluded that the neutral winds that develop as a result of the electrodynamical forcing associated with an arc do not significantly affect the intensity of the arc.

  7. Wind Turbine Structural Dynamics

    NASA Technical Reports Server (NTRS)

    Miller, D. R. (Editor)

    1978-01-01

    A workshop on wind turbine structural dynamics was held to review and document current United States work on the dynamic behavior of large wind turbines, primarily of the horizontal-axis type, and to identify and discuss other wind turbine configurations that may have lower cost and weight. Information was exchanged on the following topics: (1) Methods for calculating dynamic loads; (2) Aeroelasticity stability (3) Wind loads, both steady and transient; (4) Critical design conditions; (5) Drive train dynamics; and (6) Behavior of operating wind turbines.

  8. Neutral winds above 200 km at high latitudes.

    NASA Technical Reports Server (NTRS)

    Meriwether, J. W.; Heppner, J. P.; Stolarik, J. D.; Wescott, E. M.

    1973-01-01

    Electrically neutral, luminous clouds are a by-product of chemical releases conducted to create barium ion clouds for the measurement of electric fields. Wind measurements provided by the motions of these clouds are particularly valuable in that the motions can be directly compared with convective ion drift motions to test the importance of ion drag forces. Motion from multiple releases between 200 and 300 km from 15 rockets launched from four high-latitude locations is analyzed in this paper. The observations in the evening and midnight hours at magnetic latitudes above 65 deg strongly suggest that in these regions ion drag is the dominant force in driving neutral winds between 200 and 300 km. In the morning sector, it is evident that neutral wind observations cannot be directly interpreted in terms of ion drag; other factors must be considered.

  9. Day-To-Night Ionosphere Transport by Neutral Winds

    NASA Astrophysics Data System (ADS)

    Grebowsky, J. M.; Bougher, S. W.; Benna, M.

    2015-12-01

    Nightside low altitude nightside ionosphere production sources for the terrestrial planets are either transport from the dayside and production due to energetic particle impacts. The transport can be driven by ion coupling to the neutral atmosphere motions as part of the general atmospheric global circulation patterns and/or by ionosphere density gradients near the terminators produced as a result of a dayside source of ionization (photoionization) and a nightside sink (chemical losses). The day to night transport of ionization at high altitudes on Venus (during solar max and at Earth maintains the ionosphere throughout the night. This is not the case for Mars, where the dense ionosphere carried from the day does not extend much further than ~120 degrees solar zenith angle. Although predicted neutral wind speeds in the lower thermosphere of Mars are comparable to those on Earth and Venus, the winds at Mars can have larger impacts on horizontal transport since the planet's circumference is much smaller. One prominent effect of the winds is indicated by the observed rapid global dispersal of long-lived metal ions associated following the short, localized impact of the meteor storm associated with Comet Siding Spring . This paper will explore wind control of the low altitude Mars ionosphere ion composition measurements across the terminator from day into night, using the Neutral Gas Ion Mass Spectrometer instrument on MAVEN with the wind patterns predicted by the Mars Global Ionosphere-Thermosphere Model (M-GITM).

  10. Compact Ion and Neutral Mass Spectrometer with Ion Drifts, Temperatures and Neutral Winds

    NASA Astrophysics Data System (ADS)

    Paschalidis, Nikolaos

    2016-07-01

    In situ measurements of atmospheric neutral and ion composition and density, temperatures, ion drifts and neutral winds, are in high demand to study the dynamics of the ionosphere-theremosphere-mesosphere system. This paper presents a compact Ion and Neutral Mass Spectrometer (INMS) with impended ion drifts and temperature, and neutral winds capability for in situ measurements of ions and neutrals H, He, N, O, N2, O2. The mass resolution M/dM is approximately 10 at an incoming energy range of 0-20eV. The goal is to resolve ion drifts in the range 0 to 3000m/sec with a resolution better than 50m/sec, and neutral winds in the range of 0 to 1000m/sec with similar resolution. For temperatures the goal is to cover a dynamic range of 0 to 5000K. The INMS is based on front end optics for ions and neutrals, pre acceleration, gated time of flight, top hat ESA, MCP detectors and compact electronics. The instrument is redundant for ions and neutrals with the ion and neutral sensor heads on opposite sides and with full electronics in the middle. The ion front end includes RPA for temperature scanning and neutral front end includes angular modulation and thermionic ionization and ion blocking grids. The electronics include fast electric gating, TOF electronics, TOF binning and C&DH digital electronics. The data package includes 400 mass bins each for ions and neutrals and key housekeeping data for instrument health and calibration. The data sampling can be commanded from 0.1 to 10 sec with 1sec nominal setting. The instrument has significant onboard storage capability and a data compression scheme. The mass spectrometer version of the instrument has been flown on the Exocube mission. The instrument occupied 1.5U volume, weighed only 560 g and required nominal power of 1.6W The ExoCube mission was designed to acquire global knowledge of in-situ densities of [H], [He], [O] and H+, He+, O+ in the upper ionosphere and lower exosphere in combination with incoherent scatter radar and

  11. Wind tunnel simulations of wind turbine wake interactions in neutral and stratified wind flow.

    NASA Astrophysics Data System (ADS)

    Hancock, P. E.; Pascheke, F.

    2010-09-01

    A second programme of work is about to commence as part of a further four years of funding for the UK-EPSRC SUPERGEN-Wind large-wind-farm consortium. The first part of the initial programme at Surrey was to establish and set up appropriate techniques for both on- and off-shore boundary layers (though with an emphasis on the latter) at a suitable scale, and to build suitable rotating model wind turbines. The EnFlo wind tunnel, a UK-NCAS special facility, is capable of creating scaled neutral, stable and unstable boundary layers in its 20m long working section. The model turbines are 1/300-scale of 5MW-size, speed controlled with phase-lock measurement capability, and the blade design takes into account low Reynolds-number effects. Velocity measurements are primarily made using two-component LDA, combined with a ‘cold-wire' probe in order to measure the local turbulent heat flux. Simulation of off-shore wakes is particularly constrained because i) at wind tunnel scale the inherently low surface roughness can be below that for fully rough conditions, ii) the power required to stratify the flow varies as the square of the flow speed, and could easily be impractically large, iii) low blade Reynolds number. The boundary layer simulations, set up to give near-equilibrium conditions in terms of streamwise development, and the model turbines have been designed against these constraints, but not all constraints can be always met simultaneously in practice. Most measurements so far have been made behind just one or two turbines in neutral off- and on-shore boundary layers, at stations up to 12 disk diameters downstream. These show how, for example, the wake of a turbine affects the development of the wake of a downwind turbine that is laterally off-set by say half or one diameter, and how the unaffected part from the first turbine merges with the affected wake of the second. As expected a lower level of atmospheric turbulence causes the wakes to develop and fill-in more

  12. Quantification of Neutral Wind Variability in the Upper Thermosphere

    NASA Technical Reports Server (NTRS)

    Richards, Philip G.

    2000-01-01

    The overall objective of this grant was to: 1) Quantify thermospheric neutral wind behavior in the ionosphere. This was to be achieved by developing an improved empirical wind model. 2) Validating the procedure for obtaining winds from the height of the peak density. 3) Improving the model capabilities and making updated versions of the model available to other scientists. The approach is to use neutral winds derived from ionosonde measurements of the height of the peak electron density (h(sub m)F(sub 2)). One of the proposed first year tasks was to perform some validation studies on the method. Substantial progress has been made with regard to both the empirical model and the validation study. Funding from this grant has also enabled a number of fruitful collaborations with other researchers; one of the stated aims in the proposal. Graduate student Mayra Martinez has developed the mathematical formulation for the empirical wind model as part of her dissertation. As proposed, authors continued validation studies of the technique for determining winds from h(sub m)F(sub 2). They are submitted a paper to the Journal of Geophysical Research in December 1996 entitled "Therinospheric neutral winds at southern mid-latitudes: comparison of optical and ionosonde h(sub m)F(sub 2) methods. A second paper entitled "Ionospheric behavior at a southern mid-latitude in March 1995" has come out of the March 1995 data set and was published in The Journal of Geophysical Research. A new algorithm was developed. The ionosphere also have been modeled.

  13. Modeling of the Coupled Magnetospheric and Neutral Wind Dynamos

    NASA Technical Reports Server (NTRS)

    Thayer, Jeffrey P.

    1997-01-01

    Over the past four years of funding, SRI, in collaboration with the University of Texas at Dallas, has been involved in assessing the influence of thermospheric neutral winds on the electric field and current systems at high latitudes. The initial direction of the project was to perform a set of numerical experiments concerning the contribution of the magnetospheric and neutral wind dynamo processes, under specific boundary conditions, to the polarization electric field and/or the field-aligned current distribution at high latitudes. To facilitate these numerical experiments we developed a numerical scheme that relied on using output from the NCAR Thermosphere-Ionosphere General Circulation Model (NCAR-TIGCM), expanding them in the form of spherical harmonics and solving the dynamo equations spectrally. Once initial calculations were completed, it was recognized that the neutral wind contribution could be significant but its actual contribution to the electric field or currents depended strongly on the generator properties of the magnetosphere. Solutions to this problem are not unique because of the unknown characteristics of the magnetospheric generator, therefore the focus was on two limiting cases. One limiting case was to consider the magnetosphere as a voltage generator delivering a fixed voltage to the high-latitude ionosphere and allowing for the neutral wind dynamo to contribute only to the current system. The second limiting case was to consider the magnetosphere as a current generator and allowing for the neutral wind dynamo to contribute only to the generation of polarization electric fields. This work was completed and presented at the l994 Fall AGU meeting. The direction of the project then shifted to applying the Poynting flux concept to the high-latitude ionosphere. This concept was more attractive as it evaluated the influence of neutral winds on the high-latitude electrodynamics without actually having to determine the generator characteristics of

  14. First Thermospheric Winds and Neutral Temperatures statistics Over Oukaimeden Observatory

    NASA Astrophysics Data System (ADS)

    Kaab, Mohamed; Benkhaldoun, Zouhair; Fisher, Daniel J.; Harding, Brian; Makela, Jonathan J.; Bounhir, Aziza; Lazrek, Mohamed; Lagheryeb, Amine; Daassou, Ahmed; Khalifa, Malki

    2015-08-01

    In order to study the thermospheric-ionospheric coupling and to gain a better understanding of thermospheric neutral winds and temperatures by providing measurements over the African sector, we have deployed a new suite of instruments in Morocco: a high-resolution Fabry-Perot interferometer (FPI) and a wide-angle ionospheric imaging system. In this work, we present the statistical results from the first year of observation of thermospheric winds and neutral temperatures made at Oukaimeden Observatory, located 75 km south of Marrakesh 7° 51' W / 31° 12' N. The available data is based on the FPI measurements of Doppler shift and Doppler broadening of the 630.0-nm spectral emission caused by the dissociative recombination of O2+. Viewing the profile of trends of the winds and neutral temperatures shows that the zonal winds are eastward in the early night just after sunset with a speed of 50 m.s-1 up to 150 m.s-1, reducing over the course of the night and switching to westward flow before sunrise. The meridional winds tend to move towards the equator in the summer with speeds exceeding 150 m.s-1, while in the winter they tend to move towards the north pole with a relatively low speed that does not exceed 50 m.s-1. The neutral temperatures show a maximum around ˜1100 K at the beginning of the night and decrease as the night continues until reaching minimum values of ˜700 K before sunrise. The 630.0 nm emission intensity was relatively dim during most of the year, with the exception of a few days in late January and early February when there was a significant increase in the emission's brightness. In this paper, we discuss the instrumentation as well as the variability of these parameters day-to-day, monthly, and seasonally.

  15. Satellite Studies of Ionospheric Electric Fields and Neutral Winds

    NASA Technical Reports Server (NTRS)

    Fejer, Bela G.

    2002-01-01

    We have studied mid- and low-latitude electrodynamic and neutral thermospheric dynamic processes using measurements on board the AE-E, DE-2, and UARS (Upper Atmosphere Research Satellite) satellites, and global convection and general circulation models. These studies have determined the morphology of the equatorial zonal electric fields, the response of equatorial plasma irregularities to magnetospheric disturbances, and the time dependent response of the mid- and low latitude electric fields to magnetospheric disturbances. We have also used extensive F region zonal and meridional wind data obtained by Wind Imaging Interferometer (WINDII) instrument on board the UARS to study the latitudinal dependence of daytime disturbance winds during magnetically disturbed periods and the general characteristics of the global thermospheric disturbance wind system during geomagnetically active periods. This project has supported the PhD thesis research of John Emmert.

  16. Wind tunnel simulation of a wind turbine wake in neutral, stable and unstable wind flow

    NASA Astrophysics Data System (ADS)

    Hancock, P. E.; Zhang, S.; Pascheke, F.; Hayden, P.

    2014-12-01

    Measurements of mean velocity, Reynolds stresses, temperature and heat flux have been made in the wake of a model wind turbine in the EnFlo meteorology wind tunnel, for three atmospheric boundary layer states: the base-line neutral case, stable and unstable. The full-to-model scale is approximately 300:1. Primary instrumentation is two-component LDA combine with cold-wire thermometry to measure heat flux. In terms of surface conditions, the stratified cases are weak, but there is a strong 'imposed' condition in the stable case. The measurements were made between 0.5D and 10D, where D is the turbine disk diameter. In the stable case the velocity deficit decreases more slowly; more quickly in the unstable case. Heights at which quantities are maximum or minimum are greater in the unstable case and smaller in the stable case. In the stable case the wake height is suppressed but the width is increased, while in the unstable case the height is increased and the width (at hub height) reaches a maximum and then decreases. The turbulence in the wake behaves in a complex way. Further work needs to be done, to cover stronger levels of surface condition, requiring more extensive measurements to properly capture the wake development.

  17. Neutral hydrogen in the solar wind acceleration region

    NASA Technical Reports Server (NTRS)

    Olsen, Espen Lyngdal; Leer, Egil; Holzer, Thomas E.

    1994-01-01

    Observation of solar Ly alpha radiation scattered by coronal neutral hydrogen atoms can be used to investigate the acceleration region of the solar wind. In this paper we focus on the use of these observations to study Alfven waves, which can accelerate the solar wind plasma to flow speeds observed in high-speed streams if their amplitude at the coronal base is 20 km/s or larger. The wave amplitude is then larger than the proton thermal speed in the outer corona, so that the mean proton speed (averaged over a wave period) is significantly larger than the proton thermal speed. For low-frequency wave the hydrogen atoms follow the proton motion in the waves, while for higher frequencies the protons move relative to the neutrals. Nevertheless, in the higher frequency case, the rates for charge exchange and recombination are high enough to broaden the velocity distribution function of neutral hydrogen. Both the wave motion of the hydrogen atoms in low-frequency Alfven waves and the 'heating' by higher frequency waves lead to a broadening of the scattered solar Ly alpha line. For coronal base amplitues of 20 km/s, the line broadening increases with heliocentric distance beyond 4-5 solar radii.

  18. Propagation of large amplitude Alfven waves in the solar wind neutral sheet

    NASA Technical Reports Server (NTRS)

    Malara, F.; Primavera, L.; Veltri, P.

    1995-01-01

    Analysis of solar wind fluctuation data show that the correlation between velocity and magnetic field fluctuations decreases when going farther away from the Sun. This decorrelation can be attributed either to the time evolution of the fluctuations, carried away by the solar wind, or to the interaction between the solar wind neutral sheet and Alfven waves. To check this second hypothesis we have numerically studied the propagation of Alfven waves in the solar wind neutral sheet. The initial conditions have been set up in order to guarantee B(exp 2) = const, so that the following numerical evolution is only due to the inhomogeneity in the background magnetic field. The analysis of the results shows that compressive structures are formed, mainly in the neutral sheet where they have been identified as pressure balanced structures, i.e., tangential discontinuities. Fast perturbations, which are also produced, have a tendency to leave the simulation domain, propagating also perpendicularly to the mean magnetic field. For this reason the level of fast perturbations is always smaller with respect to the previously cited plasma balanced structures, which are slow mode perturbations. A comparison between the numerical results and some particular observational issues is also presented.

  19. Modeling of the coupled magnetospheric and neutral wind dynamos

    NASA Technical Reports Server (NTRS)

    Thayer, J. P.; Vickrey, J. F.; Heelis, R. A.; Gary, J. B.

    1995-01-01

    Work at SRI involved modeling the exchange of electromagnetic energy between the ionosphere and magnetosphere to help interpret the DE-B Poynting flux observations. To describe the electrical properties of the high-latitude ionosphere, we constructed a numerical model, from the framework provided by the Vector Spherical Harmonic (VSH) model, that determines the ionospheric currents, conductivities, and electric fields including both magnetospheric inputs and neutral wind dynamo effects. This model development grew from the earlier question of whether an electrical energy source in the ionosphere was capable of providing an upward Poynting flux. The model solves the steady-state neutral wind dynamo equations and the Poynting flux equation to provide insight into the electrodynamic role of the neutral winds. The modeling effort to determine the high-latitude energy flux has been able to reproduce many of the large-scale features observed in the Poynting flux measurements made by DE-2. Because the Poynting flux measurement is an integrated result of energy flux into or out of the ionosphere, we investigated the ionospheric properties that may contribute to the observed flux of energy measured by the spacecraft. During steady state the electromagnetic energy flux, or DC Poynting flux, is equal to the Joule heating rate and the mechanical energy transfer rate in the high-latitude ionosphere. Although the Joule heating rate acts as an energy sink, transforming electromagnetic energy into thermal or internal energy of the gas, the mechanical energy transfer rate may be either a sink or source of electromagnetic energy. In the steady state, it is only the mechanical energy transfer rate that can generate electromagnetic energy and result in a DC Poynating flux that is directed out of the ionosphere.

  20. Neutral Solar Wind Generated by Lunar Exospheric Dust at the Terminator

    NASA Technical Reports Server (NTRS)

    Collier, Michael R.; Stubbs, Timothy J.

    2007-01-01

    We calculate the flux of neutral solar wind observed on the lunar surface at the terminator due to solar wind protons penetrating exospheric dust with: (1) grains larger that 0.1 microns and (2) grains larger than 0.01 microns. For grains larger than 0.1 microns, the ratio of the neutral solar wind to solar wind flux is estimated to be approx.10(exp -4)-10(exp -3) at solar wind speeds in excess of 800 km/s, but much lower (less than 10(exp -5) at average to low solar wind speeds. However, when the smaller grain sizes are considered, the ratio of the neutral solar wind flux to solar wind flux is estimated to be greater than or equal to 10(exp -5) at all speeds and at speeds in excess of 700 km/s reaches 10(exp -3)-10(exp -2). These neutral solar wind fluxes are easily measurable with current low energy neutral atom instrumentation. Observations of neutral solar wind from the surface of the Moon could provide a very sensitive determination of the distribution of very small dust grains in the lunar exosphere and would provide data complementary to optical measurements at ultraviolet and visible wavelengths. Furthermore, neutral solar wind, unlike its ionized counterpart, is .not held-off by magnetic anomalies, and may contribute to greater space weathering than expected in certain lunar locations.

  1. Ion-neutral coupling effects on low-latitude thermospheric evening winds

    NASA Astrophysics Data System (ADS)

    Evonosky, W.; Richmond, A. D.; Fang, T.-W.; Maute, A.

    2016-05-01

    We examine the forces that determine zonal wind structure in the low-latitude evening thermosphere and its relation with ion-neutral coupling. These winds drive the evening F region dynamo that affects the equatorial ionization anomaly (EIA) and the generation of plasma irregularities. Forces are calculated using the Thermosphere-Ionosphere-Electrodynamics General Circulation Model coupled with the Global Ionosphere-Plasmasphere model. At 19 LT, the horizontal pressure gradient dominates the net acceleration of neutral winds below ˜220 km, while it tends to be offset by ion drag and viscosity higher up. The eastward pressure-gradient acceleration above 200 km increases approximately linearly with height and tends to be similar for different latitudes and different levels of solar activity. The pressure-gradient and ion-drag forces in the central F region approximately balance for field lines that pass through the EIA. Viscosity is an important additional force at non-EIA latitudes and in the bottomside and topside EIA ionosphere. An increase in E region drag on plasma convection due to increased nighttime ionization causes both the ion and neutral velocities in the F region to decrease, while the velocity difference tends to be maintained. The presence of a low-latitude evening time vertical shear in the zonal wind is associated primarily with a strong eastward pressure-gradient acceleration at high altitude that reverses the daytime westward wind and a weak low-altitude pressure-gradient acceleration of either eastward or westward direction that fails to reverse the low-altitude westward wind present in the afternoon.

  2. Thermospheric neutral wind measurement by three rocket-released Lithium clouds: WIND campaign

    NASA Astrophysics Data System (ADS)

    Yamamoto, Masa-Yuki; Yamamoto, Masa-Yuki; Watanabe, Shigeto; Yokoyama, Yuki; Habu, Hiroto; Abe, Takumi; Yamamoto, Mamoru; Otsuka, Yuichi; Saito, Akinori; Ono, Takayuki; Nakamura, Masato

    During a Japanese sounding rocket experiment called "WIND" campaign, the S-520-23 rocket was launched from Uchinoura, Japan (131.08° E, 31.25° N) at 19:20 LT on Sep. 2, 2007, in order to investigate interaction between neutral and plasma atmosphere in midlatitude thermosphere. Main purpose of the campaign is to establish a new technology of chemical release in wide altitude range of the thermosphere. Scientific target of the WIND campaign is to measure neutral wind in evening condition of generating MSTID (Medium-Scale Travelling Ionospheric Disturbances). Three Lithium releases were successfully carried out at 230 km, 193 km, and 144 km altitudes by newly developed LES (Lithium Ejection System). Thermospheric neutral wind profile from 250 km down to 120 km was successfully measured along its downleg by taking sequential images from 4 independent ground sites. Imaging of the resonance scattering luminescence of Lithium was operated by newly developed tele-centric lens with wide FOV of 110 degrees with a 20 nm width band-pass filter at around 670.8 nm. At the beginning of 1st release, luminescence intensity more than 1 M rayleigh was observed by 125 g Lithium injection. Triangulation dataset of the three Lithium clouds was obtained until 40 minutes after the 1st release. As a preliminary result, SE-ward wind of 80 m/s or more at 250 km, SSW-ward 100 m/s wind at 200 km, SSW-ward 80 m/s wind at 150 km, and NNE-ward 60 m/s wind at 120 km were obtained, respectively. Strong wind shear in an altitude range between 120 km and 150 km was also found. Observed initial rate of Lithium diffusion speed of 3.2 km/s at 250 km was comparable to thermal diffusion speed in a released temperature condition of 1600 K. Before merging the Lithium clouds into surrounding atmosphere, flight velocity of the rocket itself might affect on the motion of Lithium clouds until about 150 s after the release. In this talk, Lithium release experiment in midlatitude thermosphere will be discussed

  3. Structural basis of influenza virus neutralization

    PubMed Central

    Han, Thomas; Marasco, Wayne A.

    2010-01-01

    Although seasonal influenza vaccines play a valuable role in reducing the spread of the virus at the population level, ongoing viral evolution to evade immune responses remains problematic. No current vaccines are likely to elicit enduring protection in the face of emerging and re-emerging influenza viruses that rapidly undergoing antigenic drift. Eliciting broadly cross-neutralizing antibody responses against influenza virus is a crucial goal for seasonal and pandemic influenza vaccine preparation. Recent three-dimensional structure information obtained from crystallization of influenza antigens in complex with neutralizing antibodies (nAbs) have provided a framework for interpreting antibody-based viral neutralization that should aid in the design of vaccine immunogens. Here, we will review current knowledge of the structure-based mechanisms contributing to the neutralization and neutralization escape of influenza viruses. We will also explore the potential for this structure-based approach to overcome the challenge of obtaining the highly desired “universal” influenza vaccine. PMID:21251008

  4. Large Eddy Simulation of Wind Turbine Wakes in Prescribed Neutral and Non-Neutral Atmospheric Boundary Layers

    NASA Astrophysics Data System (ADS)

    Sarlak Chivaee, Hamid; Sørensen, Jens N.

    2014-12-01

    Large eddy simulation (LES) of an infinitely long wind farm in a fully developed flow is carried out based on solution of the incompressible Navier-Stokes equations. The wind turbines are modeled as equivalent rotating actuator disks by applying aerodynamic loads on the flow field using tabulated aerodynamic lift and drag coefficients to save computational time. As a substitute to standard wall modeling LES, a ''prescribed mean shear" profile (hereafter called PMS) approach has been implemented and analysed for generating the desired turbulent shear flow. It is applied on Neutral, Stable and Convective atmospheric boundary layers in presence of the -actuator disc represented- wind turbines and qualitatively meaningful results of mean and fluctuating velocity field is obtained. The effect of four different sub-grid scale (SGS) models on the flow structure is investigated and it is seen that subgrid scale modeling (in particular, the Mix-O and Smagorinsky models) improves the accuracy of the simulations. An optimal grid resolution is also proposed for this kind of simulation.

  5. How uncertainty in the neutral wind limits the accuracy of ionospheric modeling and forecasting

    NASA Astrophysics Data System (ADS)

    David, Michael; Sojka, J. J.; Schunk, R. W.

    2016-01-01

    One of the most important input fields for an ionospheric model is the horizontal neutral wind. The primary mechanism by which the neutral wind affects ionospheric densities is the inducement of an upward or downward ion drift along the magnetic field lines; this affects the rate at which ions are lost through recombination. The magnitude of this effect depends upon the dip angle of the magnetic field; for this reason, the impact of the neutral wind is somewhat less in polar regions than at mid-latitudes. It is unfortunate that observations of the neutral wind are relatively scarce, as compared for example with observations of the Earth's electric field or auroral precipitation, and that the existing climatological models of the neutral wind are thus sharply limited in theirresolution. The observational data base of thermospheric winds is not sufficient to adequately constrain a three-dimensional model across a variety of conditions such as solar cycle, season, geomagnetic activity, and so on. Using the physics-based Time Dependent Ionospheric Model (TDIM) of Utah State University, we look for a quantitative answer to this question: How severe is the limitation imposed on ionospheric models by an uncertain specification of the neutral wind? We find that ionospheric modeling depends upon a detailed specification of the neutral wind to the extent that, if a climatologically averaged wind model is being used as a driver, this will lead to unavoidable uncertainties of 20-30% in the modeled F-region densities or Total Electron Content (TEC).

  6. The heliospheric neutral hydrogen density profile in the presence of a solar wind shock

    NASA Technical Reports Server (NTRS)

    Gangopadhyay, P.; Judge, D. L.

    1989-01-01

    The effect of a postulated nearby solar wind shock on the radial density profile of the cold inflowing neutral hydrogen atoms is studied. It is found that a nearby solar wind shock strongly affects the neutral hydrogen breeze. Model calculation reveals that the strongly perturbed hydrogen atom distribution beyond a solar wind shock can be remotely detected by observation of the radial dependence of the backscattered UV glow from the deep space probes Pioneer 10/11 and Voyager 1/2.

  7. Neutral line chaos and phase space structure

    NASA Technical Reports Server (NTRS)

    Burkhart, Grant R.; Speiser, Theodore W.; Martin, Richard F., Jr.; Dusenbery, Paul B.

    1991-01-01

    Phase space structure and chaos near a neutral line are studied with numerical surface-of-section (SOS) techniques and analytic methods. Results are presented for a linear neutral line model with zero crosstail electric field. It was found that particle motion can be divided into three regimes dependening on the value of the conserved canonical momentum, Py, and the conserved Hamiltonian, h. The phase space structure, using Poincare SOS plots, is highly sensitive to bn = Bn/B0 variations, but not to h variations. It is verified that the slow motion preserves the action, Jz, as evaluated by Sonnerup (1971), when the period of the fast motion is smaller than the time scale of the slow motion. Results show that the phase space structure and particle chaos depend sensitively upon Py and bn, but are independent of h.

  8. Kalman filter based data fusion for neutral axis tracking in wind turbine towers

    NASA Astrophysics Data System (ADS)

    Soman, Rohan; Malinowski, Pawel; Ostachowicz, Wieslaw; Paulsen, Uwe S.

    2015-03-01

    Wind energy is seen as one of the most promising solutions to man's ever increasing demands of a clean source of energy. In particular to reduce the cost of energy (COE) generated, there are efforts to increase the life-time of the wind turbines, to reduce maintenance costs and to ensure high availability. Maintenance costs may be lowered and the high availability and low repair costs ensured through the use of condition monitoring (CM) and structural health monitoring (SHM). SHM allows early detection of damage and allows maintenance planning. Furthermore, it can allow us to avoid unnecessary downtime, hence increasing the availability of the system. The present work is based on the use of neutral axis (NA) for SHM of the structure. The NA is tracked by data fusion of measured yaw angle and strain through the use of Extended Kalman Filter (EKF). The EKF allows accurate tracking even in the presence of changing ambient conditions. NA is defined as the line or plane in the section of the beam which does not experience any tensile or compressive forces when loaded. The NA is the property of the cross section of the tower and is independent of the applied loads and ambient conditions. Any change in the NA position may be used for detecting and locating the damage. The wind turbine tower has been modelled with FE software ABAQUS and validated on data from load measurements carried out on the 34m high tower of the Nordtank, NTK 500/41 wind turbine.

  9. Altitude distribution of neutral wind responses to external forces in the polar upper atmosphere

    NASA Astrophysics Data System (ADS)

    Jee, Geonhwa; Lee, Changsup; Song, In-Sun; Kim, Jeong-Han; Kim, Yong Ha; Wu, Qian

    2016-04-01

    Neutral winds in the polar upper atmosphere are mainly determined, in addtion to solar and auroral heatings, by external forces such as plasma convection driven by magnetospheric electric field and atmospheric waves propagated from the lower atmosphere. In particular, the effects of plasma convection via ion drag also rely on the ion density produced not only by solar production but also by energetic particle precipitation. On the other hand, the atmospheric waves such as gravity wave, planetary wave, and tide, propagating from the lower atmosphere, should deposit energy and momentum into the upper atmosphere and affect the neutral winds in the polar region. Then, which external forces dominate the neutral winds in the polar upper atmosphere? What is the boundary region in which the transition occurs from one to the other forces? In order to address these questions, in this study, the effects of the external forces on the neutral winds are investigated using the observations for the neutral winds by Fabry-Perot Interferometer (FPI) at Jang Bogo Station (JBS), Antarctica. The initial result indicates that the effects of plasma convection dominates the neutral winds even at 97 km altitude but the winds at 87 km altitude seem to be dominated by the lower atmospheric wave effects, regardless of season.

  10. Satellite accelerometer measurements of neutral density and winds during geomagnetic storms

    NASA Technical Reports Server (NTRS)

    Marcos, F. A.; Forbes, J. M.

    1986-01-01

    A new thermospheric wind measurement technique is reported which is based on a Satellite Electrostatic Triaxial Accelerometer (SETA) system capable of accurately measuring accelerations in the satellite's in-track, cross-track and radial directions. Data obtained during two time periods are presented. The first data set describes cross-track winds measured between 170 and 210 km during a 5-day period (25 to 29 March 1979) of mostly high geomagnetic activity. In the second data set, cross-track winds and neutral densities from SETA and exospheric temperatures from the Millstone Hill incoherent scatter radar are examined during an isolated magnetic substorm occurring on 21 March 1979. A polar thermospheric wind circulation consisting of a two cell horizontal convection pattern is reflected in both sets of cross-track acceleration measurements. The density response is highly asymmetric with respect to its day/night behavior. Latitude structures of the density response at successive times following the substorm peak suggest the equatorward propagation of a disturbance with a phase speed between 300 and 600 m/s. A deep depression in the density at high latitudes (less than 70 deg) is evident in conjunction with this phenomenon. The more efficient propagation of the disturbance to lower latitudes during the night is probably due to the midnight surge effect.

  11. Investigation of Neutral Wind Effects on the Global Joule Heating Rate Using MHD and TI Models

    NASA Astrophysics Data System (ADS)

    Kalafatoglu, E.; Kaymaz, Z.

    2013-12-01

    Precise calculation of global Joule heating rate is a long standing question in thermosphere-ionosphere coupling processes. The absence of the complete and direct, in-situ measurements of the parameters involved in the calculation of Joule heating such as the conductivity of the medium, small-scale variations of electric fields, and neutral winds at the ionospheric heights poses a great uncertainty in its determination. In this work, we study the effects of the neutral wind on the global Joule heating rate. Most of the time, owing to above mentioned difficulties the effects of the neutral wind have been neglected in the calculations. We investigate their effects using BATSRUS MHD model, TIEGCM and GITM. Using horizontal current density, Cowling conductivity, and Pedersen conductivities from the MHD model, we calculate the joule heating rate with and without the neutral wind contribution. We apply the procedure for March 2008 magnetospheric substorm events and quantify the differences to show the neutral wind contribution. We compare the results with those obtained using neutral wind velocities from TIEGCM and GITM models. This way while we compare and demonstrate the discrepancies between the models, we also provide an assessment for the integration of thermospheric and magnetospheric models.

  12. Assimilating Storm-time Neutral Winds in Ionospheric-Thermospheric State Estimation

    NASA Astrophysics Data System (ADS)

    Datta-Barua, S.; Miladinovich, D.; Makela, J. J.; Bust, G. S.

    2015-12-01

    During geomagnetic storms at mid-latitudes both electrodynamic disturbances and neutral composition variations contribute to time evolving and localized variations in the plasma content of the ionosphere. While the most plentiful data are typically Global Navigation Satellite System (GNSS) based measurements of total electron content (TEC), assimilation of measurements of the ionospheric-thermospheric state itself, i.e., neutral winds, can improve the fidelity of the result. Fabry-Perot interferometers (FPIs) measure emissions of thermospheric oxygen, giving line-of-sight wind speeds. During storm-times however, these FPI measurements may also detect a non-thermal oxygen source, yielding a measurement that is not strictly of the thermospheric wind [Makela et al., 2014]. The sign of non-thermal oxygen is in the apparent large 50 to 100 m/s vertical winds. This raises the question: what happens when we try to assimilate direct measurements of the wind but some of those measurements are "contaminated" by a non-thermal source? We present results of a Kalman Filtered data assimilative experiment ingesting neutral wind measurements made by a 630.0 nm FPI sited in the mid-latitude U.S. during the geomagnetic storm of October 25, 2011. Ionospheric Data Assimilation 4-Dimensional (IDA4D) estimates time-varying plasma densities from GNSS TEC. These densities are ingested without, and with, respectively, FPI neutral wind data into Estimating Model Parameters with Ionospheric Reverse Engineering (EMPIRE). EMPIRE uses background electric potential and neutral wind models, to produce an optimized estimate of both ExB drift and neutral wind based on the data ingested. We compare the estimated horizontal neutral wind at the FPI measurement locations at about 250 km altitude, first using electron densities without ingesting FPI data. Then plasma densities plus half the FPI data are ingested to estimate neutral winds. These wind estimates are then compared to the FPI data that were

  13. Equatorial F region neutral winds and shears near sunset measured with chemical release techniques

    NASA Astrophysics Data System (ADS)

    Kiene, A.; Larsen, M. F.; Kudeki, E.

    2015-10-01

    The period near sunset is a dynamic and critical time for the daily development of the equatorial nighttime ionosphere and the instabilities that occur there. It is during these hours that the preconditions necessary for the later development of Equatorial Spread F (ESF) plasma instabilities occur. The neutral dynamics of the sunset ionosphere are also of critical importance to the generation of currents and electric fields; however, the behavior of the neutrals is experimentally understood primarily through very limited single-altitude measurements or measurements that provide weighted altitude means of the winds as a function of time. To date, there have been very few vertically resolved neutral wind measurements in the F region at sunset. We present two sets of sounding rocket chemical release measurements, one from a launch in the Marshall Islands on Kwajalein atoll and one from Alcantara, Brazil. Analysis of the release motions has yielded vertically resolved neutral wind profiles that show both the mean horizontal winds and the vertical shears in the winds. In both experiments, we observe significant vertical gradients in the zonal wind that are unexpected by classical assumptions about the behavior of the neutral wind at these altitudes at sunset near the geomagnetic equator.

  14. Detailed Atomic Structure of Neutral and Near-Neutral Systems

    SciTech Connect

    Oliver, Paul; Hibbert, Alan

    2011-05-11

    This paper highlights the issues which need to be addressed in undertaking accurate calculations of multi-electron atoms and ions, particularly at or near the neutral end of an isoelectronic sequence. We illustrate the processes through two calculations--of transitions in Cl I and Sn II--and discuss the convergence of our results as well as updating previous work. In particular, in the case of Cl I, we propose new identifications of the levels involved in certain transitions which are important in determining the abundance of chlorine in the inter-stellar medium (ISM), while in singly ionised tin, our calculations suggest a re-evaluation of the the abundance of tin in the ISM. We also confirm recent identification of Sn II lines seen in tokamak plasmas.

  15. A new satellite-borne neutral wind instrument for thermospheric diagnostics

    NASA Astrophysics Data System (ADS)

    Earle, G. D.; Klenzing, J. H.; Roddy, P. A.; Macaulay, W. A.; Perdue, M. D.; Patrick, E. L.

    2007-11-01

    The bulk motion of the neutral gas at altitudes between about 200 and 600km is an important factor in predicting the onset of plasma instabilities that are known to distort and/or disrupt high frequency radio communications. These neutral winds have historically been quite difficult to measure, especially from a moving spacecraft. A new space science instrument called the ram wind sensor has been developed to measure the component of the neutral gas velocity that lies along the orbit track of a satellite in low Earth orbit. Laboratory tests of an engineering model of the instrument have been carried out using a supersonic neutral argon beam, in order to validate the measurement concept. The results show that the technique is viable for measurements of neutral flow velocities in future satellite missions.

  16. Neutral winds derived from IRI parameters and from the HWM87 wind model for the sundial campaign of September, 1986

    NASA Technical Reports Server (NTRS)

    Miller, K. L.; Hedin, A. E.; Wilkinson, P. J.; Torr, D. G.; Richards, P. G.

    1990-01-01

    Meridional neutral winds derived from the height of the maximum ionization of the F2 layer are compared with values from results of the HWM87 empirical neutral wind model. The time period considered is the SUNDIAL-2 campaign, 21 Sept. through 5 Oct. 1986. Winds were derived from measurements by a global network of ionosondes, as well as from similar quantities generated by the International Reference Ionosphere. Global wind patterns from the three sources are similar. Differences tend to be the result of local or transient phenomena that are either too rapid to be described by the order of harmonics of the empirical models, or are the result of temporal changes not reproduced by models based on average conditions.

  17. Solar wind and coronal structure

    NASA Technical Reports Server (NTRS)

    Withbroe, G. L.

    1983-01-01

    Spectroscopic diagnostic techniques used to determine the coronal source region of the solar wind, and results of preliminary applications are examined. The topics reviewed are magnetic fields, coronal mass ejections, coronal holes, flow velocities, coronal temperatures, fine spatial structure, and future observational programs. The physical mechanisms responsible for plasma heating, solar-wind acceleration, the transport of mass momentum and energy, and the spatial differentiation of chemical abundances are also discussed. Among the data presented are Skylab's white-light coronagraph photograph of a coronal transient, X-ray photographs of the corona, and spectroheliograms showing bright points overlying polar plumes, and macrospicules.

  18. Comparison of zonal neutral winds with equatorial plasma bubble and plasma drift velocities

    NASA Astrophysics Data System (ADS)

    Chapagain, Narayan P.; Fisher, Daniel J.; Meriwether, John W.; Chau, Jorge L.; Makela, Jonathan J.

    2013-04-01

    A one-year dataset spanning March 2011 to March 2012 of coincident observations of nighttime thermospheric zonal neutral winds, equatorial plasma bubble (EPB) velocities, and zonal plasma drifts is used to examine the relationship between the thermosphere and the ionosphere near the geomagnetic equator over Peru. Thermospheric neutral winds are determined by using a bistatic Fabry-Perot interferometer (FPI) experiment located at Merihill and Nazca in Peru. The ambient plasma drift velocities were obtained using the incoherent scatter radar at the Jicamarca Radio Observatory in Peru. The EPB zonal velocities were estimated utilizing images of the OI 630.0 nm emission recorded by a narrow-field optical imaging system at the Cerro Tololo Inter-American Observatory in Chile. The joint analysis of these datasets illustrates that the nighttime and night-to-night variations in the zonal neutral winds, EPB velocities, and plasma drifts are well correlated. This consistent result of the local time variations of the neutral winds with that of EPB and plasma drifts illustrates that the F-region dynamo is, in general, fully activated. However, at times, the magnitude of the EPB velocities and the plasma drifts are different from the neutral winds. It is plausible that such a difference is due either to the effect of polarization electric fields developed inside the EPB or due to the latitudinal gradient of the neutral winds and EPB velocity measurements since the EPB velocities are estimated at a higher latitude, corresponding to an apex altitude of ~400 km, than the wind estimates, which derive from an apex altitude of ~250 km.

  19. Behavior of neutral wind gradients at meteor heights over midlatitude stations

    NASA Technical Reports Server (NTRS)

    Devara, P. C. S.; Chandrasekhar, G.; Ahmed, M. I.

    1985-01-01

    The variation of wind gradients in the altitude range of 80 to 100 km, which contributes information on propagational characteristics of wave phenomena prevailing at those altitudes, was studied. Diurnal and semidiurnal components of the zonal (EW) and meridional (NS) neutral wind data collected over Atlanta using the Georgia Tech Meteor Wind Radar Facility during the period of August 1974 through March of 1978 over the height range of 80 to 100 km are analyzed in detail to obtain information on height gradients in amplitude and phase of neutral wind components over height intervals of 80 to 90 and 90 to 100 km. The details of the data analysis, major results, and conclusions are presented.

  20. Thermal coupling of protons and neutral hydrogen with anisotropic temperatures in the fast solar wind

    NASA Astrophysics Data System (ADS)

    Allen, Lorraine A.; Habbal, Shadia R.; Li, Xing

    2000-10-01

    The thermal coupling between the neutral hydrogen and protons in the inner corona is explored by extending the study of Allenet al. [1998] to include anisotropic proton temperature to determine what the neutral hydrogen Ly α spectral line measurements reveal about the proton temperature, temperature anisotropy, and outflow velocity in the fast solar wind. The anisotropic proton temperature is produced by ion cyclotron resonant interaction of protons with high-frequency waves, produced by a nonlinear cascade at the Kolmogorov dissipation rate from dominant lower-frequency Alfvén waves. As a result of the coupling between the respective parallel and perpendicular components of the neutral hydrogen and proton temperatures, a greater temperature anisotropy in the neutral hydrogen develops as compared to the case when the proton temperature is isotropic. The neutral hydrogen and proton effective temperatures (Teff), incorporating both random and wave motions of the particles, and outflow velocities, are comparable below ~3Rs. Neutral hydrogen anisotropy ratios, TH(eff)/T∥, ~4 below 3Rs are readily attained, in agreement with observations. Below ~3Rs, these reflect the proton anisotropy ratio. For plasma conditions typical of the fast solar wind, these results imply that the measured Ly α spectral line profiles, from which the neutral hydrogen temperature, anisotropy ratio, and outflow velocity are inferred, are equivalent to measurements of protons below ~3Rs. Beyond this distance the width of the measured Ly α spectral lines provides a lower limit to the proton effective temperature and temperature anisotropy in the inner corona.

  1. WINCS v.2 for the Neutral Wind and Ion-drift in the Thermosphere/Ionosphere

    NASA Astrophysics Data System (ADS)

    Herrero, F. A.; Nicholas, A. C.

    2013-12-01

    The Wind Ion-drift Neutral Composition Suite (WINCS) has been updated to increase sensitivity to wind/ion-drift change and to further reduce risk and cost. Description of the new neutral wind/ion-drift spectrometer component of WINCS will be given with data results from simulations and laboratory tests of WINCS version 2. A 20-fold increase in wind/ion-drift sensitivity brings their uncertainties to about × 0.5 m/s; corresponding to a pointing uncertainty of × 0.005°. This precision improves accuracy in the wind/ion-drift when used with new star cameras that provide ×0.005° or better pointing accuracy; thus allowing vertical wind and vertical ion-drift measurements over broad regions of the upper atmosphere. The new design uses a larger aperture (0.1cm diameter instead of the 0.02cm diameter of WINCS v.1), and replaces the energy-scanning energy analyzer with a 30° PPA (parallel plate analyzer) energy spectrograph that simultaneously measures all energies of interest. These two features increase the signal to enable the new wind/ion-drift precisions stated above. Risk and cost reduction follow from the new electro-mechanical format that combines spectrometer mechanical mounting with the actual electrical connection. The presentation will close with discussion of cross-track and in-track wind and ion-drift components to emphasize the requirement of the energy analyzer in obtaining the magnitude of the total velocity in both cross-track and in-track winds and ion-drifts - that is, the total velocity of the neutrals or ions incident upon WINCS.

  2. Synthetic thermosphere winds based on CHAMP neutral and plasma density measurements

    NASA Astrophysics Data System (ADS)

    Gasperini, F.; Forbes, J. M.; Doornbos, E. N.; Bruinsma, S. L.

    2016-04-01

    Meridional winds in the thermosphere are key to understanding latitudinal coupling and thermosphere-ionosphere coupling, and yet global measurements of this wind component are scarce. In this work, neutral and electron densities measured by the Challenging Minisatellite Payload (CHAMP) satellite at solar low and geomagnetically quiet conditions are converted to pressure gradient and ion drag forces, which are then used to solve the horizontal momentum equation to estimate low latitude to midlatitude zonal and meridional "synthetic" winds. We validate the method by showing that neutral and electron densities output from National Center for Atmospheric Research (NCAR) Thermosphere Ionosphere Mesosphere Electrodynamics-General Circulation Model (TIME-GCM) can be used to derive solutions to the momentum equations that replicate reasonably well (over 85% of the variance) the winds self-consistently calculated within the TIME-GCM. CHAMP cross-track winds are found to share over 65% of the variance with the synthetic zonal winds, providing further reassurance that this wind product should provide credible results. Comparisons with the Horizontal Wind Model 14 (HWM14) show that the empirical model largely underestimates wind speeds and does not reproduce much of the observed variability. Additionally, in this work we reveal the longitude, latitude, local time, and seasonal variability in the winds; show evidence of ionosphere-thermosphere (IT) coupling, with enhanced postsunset eastward winds due to depleted ion drag; demonstrate superrotation speeds of ˜27 m/s at the equator; discuss vertical wave coupling due the diurnal eastward propagating tide with zonal wave number 3 and the semidiurnal eastward propagating tide with zonal wave number 2.

  3. A case study of the thermospheric neutral wind response to geomagnetic storm

    NASA Astrophysics Data System (ADS)

    Jiang, Guoying; Zhang, Shunrong; Wang, Wenbin; Yuan, Wei; Wu, Qian; Xu, Jiyao

    A minor geomagnetic storm (Kp=5) occurred on March 27-28, 2012. The response of the thermospheric neutral wind at ~ 250 km to this storm was investigated by the 630.0 nm nightglow measurements of Fabry-Perot interferometers (FPIs) over Xinglong (geographic location: 40.2N, 117.4E; geomagnetic location: 29.8N, 193.2E) and Millstone Hill (geographic location: 42.6N, 71.5W; geomagnetic location: 53.1N, 65.1W). Our results show that the minor storm on March 27-28, 2012 obviously effected on the thermospheric neutral winds over Xinglong and Millstone Hill, especially Millstone Hill had larger response because of its higher geomagnetic latitude. Another interesting result is that a small variation in geomagnetic activity (Kp=2.7) could enough introduce a clear disturbance in the nighttime thermospheric neutral wind over Millstone hill. NCAR-TIME-GCM (National Center for Atmospheric Research-Thermosphere Ionosphere Mesosphere Electrodynamics-General Circulation Model) was employed to study the evolution and mechanism of the thermospheric neutral wind response.

  4. Optical observations of thermospheric neutral winds at Arecibo between 1980 and 1987

    SciTech Connect

    Burnside, R.G.; Tepley, C.A. )

    1989-03-01

    Since 1980, optical observations of nighttime thermospheric winds have been made using a Fabry-Perot interferometer at the Arecibo Observatory, Puerto Rico. High-resolution spectra of the O({sup 1}D) airglow emission at 630.0 nm are obtained by observing at eight equally spaced azimuth positions and a fixed zenith angle of 60{degree}. The neutral wind field is inferred by assuming that each component of the wind velocity vector may be expanded in a linear Taylor expansion about a point directly above the observatory. Both the zonal and meridional components of the thermospheric wind field are observed to have well-defined seasonal and nocturnal variations. For each year between 1980 and 1987, eastward flow was observed in the evening hours, with an average peak velocity of about 100 m s{sup {minus}1} near 2,200 AST. In the winter months, the zonal wind generally remains eastward throughout the night. However, in summer, a reversal to westward flow is usually observed after local midnight. In the meridional direction, the largest equatorward velocities are observed in summer. A reduction (or reversal) in the meridional wind velocity is most often observed after midnight in the summer and equinoctial months. The authors find that the nocturnal and seasonal variations in the neutral wind field at Arecibo are remarkably unaffected by changes in the solar cycle.

  5. Wind farm performance in conventionally neutral atmospheric boundary layers with varying inversion strengths

    NASA Astrophysics Data System (ADS)

    Allaerts, Dries; Meyers, Johan

    2014-06-01

    In this study we consider large wind farms in a conventionally neutral atmospheric boundary layer. In large wind farms the energy extracted by the turbines is dominated by downward vertical turbulent transport of kinetic energy from the airflow above the farm. However, atmospheric boundary layers are almost always capped by an inversion layer which slows down the entrainment rate and counteracts boundary layer growth. In a suite of large eddy simulations the effect of the strength of the capping inversion on the boundary layer and on the performance of a large wind farm is investigated. For simulations with and without wind turbines the results indicate that the boundary layer growth is effectively limited by the capping inversion and that the entrainment rate depends strongly on the inversion strength. The power output of wind farms is shown to decrease for increasing inversions.

  6. Interaction of the solar wind with interstellar neutral hydrogen - Three-fluid model

    NASA Technical Reports Server (NTRS)

    Isenberg, P. A.

    1986-01-01

    It is commonly assumed in models of the solar wind-interstellar neutral hydrogen interaction that the ionized interstellar particles are quickly assimilated into the solar wind proton population and 'become indistinguishable' from the original solar wind. This assumption leads to the prediction that the solar wind proton temperature should increase with radius in the outer heliosphere. This temperature increase has not been observed. It is pointed out that assimilation of the interstellar particles to the point of indistinguishability takes place on the very long Coulomb collision time scale, and is not expected to occur within the heliosphere. Results are presented of a three-fluid model of the solar wind which consists of comoving thermal populations of protons of solar origin, protons produced by ionization of interstellar hydrogen, and electrons. The steady-state results yield a solar wind with a 'core' proton distribution which cools adiabatically, and a 'halo' of interstellar pickup protons which is maintained near 10 to the 7th K by the energy input of continued ionization and pickup. Such a distribution will not be observed to manifest the temperature increase at large heliocentric distances which is predicted from a one-fluid analysis. Further time-dependent calculations show a strong correlation between the densities of the solar wind and the interstellar pickup protons. It is suggested that the interstellar pickup population may be observable by the Voyager plasma instruments in low resolution mode during periods of high solar wind density and low solar wind temperature.

  7. ANALYTIC MODEL OF THE IBEX RIBBON WITH NEUTRAL SOLAR WIND BASED ION PICKUP BEYOND THE HELIOPAUSE

    SciTech Connect

    Moebius, E.; Liu, K.; Funsten, H.; Gary, S. P.; Winske, D.

    2013-04-01

    Energetic neutral atom (ENA) full sky maps obtained with the Interstellar Boundary Explorer revealed a surprising narrow band of increased intensity, the Ribbon, which has been attributed to the ordering effect of the interstellar magnetic field immediately outside the heliosphere. Among models to explain the enhanced ENA Ribbon intensity, Heerikhuisen et al. base theirs on neutral solar wind origin. It reflects the Ribbon angular and energy distribution correctly, but experiences inherent challenges from the long-term stability of the pickup ion (PUI) ring in velocity space, required for the observed ENA fluxes, and from time variations observed after less than one year due to the long integration length. We provide a simplified analytic model of the neutral solar wind, PUI production beyond the heliopause, and subsequent ENA production. We include convection of the PUIs with the interstellar flow toward the heliopause perpendicular to the interstellar magnetic field, thus far not in any model, extinction of the outward propagating neutral solar wind, and of the PUIs and ENAs on their way inward. Based on hybrid simulations of PUI driven instabilities, with injection rates from this model, scattering and isotropization of the PUIs is noticeably weaker than previously thought, yet too fast for ENA production. Assuming a narrow PUI velocity ring, we find a strong concentration of the ENA origin just outside the heliopause and Ribbon intensities comparable with the observations. Conversely, an isotropic PUI distribution produces ENA fluxes factor of ten too low, thus reemphasizing the need of very slow scattering.

  8. Neutral wind and electric field calculation from monostatic IS radar measurements by means of stochastic inversion

    NASA Astrophysics Data System (ADS)

    Aikio, A.; Nygren, T.; Kuula, R.; Voiculescu, M.

    2012-04-01

    We present the principles of a new method that utilises stochastic inversion in determining the electric field and neutral wind from monostatic beam swing incoherent scatter (IS) radar measurements (Nygren et al., J. Geophys. Res., 2011). The method consists of two stages. In the first inversion of beam-aligned ion velocities from the F region, we get the two perpendicular electric field components and the field-aligned ion velocity profile together with their error estimates. The number of beam directions can be freely selected, as long as there are at least three non-coplanar directions. Typically, we use the best possible time resolution for electric field, which is about 6 min for the Tromso CP2 experiment. In the second stage, the input to the inversion problem consists of beam-aligned ion velocities from the E region as well as the calculated electric field components. The number of applied beam cycles for E-region winds is typically greater than in the first inversion problem, since the neutral wind usually changes more slowly than the electric field. The solution of the second inversion problem gives the most probable values of the three neutral wind components and their errors. In the method described above, a stationary and horizontally homogeneous ionosphere has been assumed. These assumptions are not necessarily valid during a single beam cycle or within the whole measurement region. Disturbances in the receiver may also cause errors. Thus the results may contain errors, which are not of statistical nature. A method has been developed that finds and rejects such measurements from the analysis described above (Nygrén et al., submitted). In consequence, more reliable results for electric fields and neutral winds are expected.

  9. The Wind and Temperature Spectrometer (WTS) in the Atmospheric Neutral Density Experiment (ANDE) Satellite

    NASA Technical Reports Server (NTRS)

    Herrero, F. A.; Vancil, B.; Nicholas, A.; Zaruba, C.; Beasley, L.

    2004-01-01

    Miniaturization efforts in new spectrometers for ionosphere/thermosphere investigations of the ion-drifts and neutral winds and corresponding temperatures make possible very light (about 250 g) packages consuming less than 0.4 W. Previously described, our approach measures the angular and energy distributions of neutral atoms and molecules (or ions) in two perpendicular planes; using those distributions to determine the full wind vector, the temperature and the relative densities of O and N2, as required for the ANDE mission. The measurements require two separate electron impact ion sources each with its own electron beam cathode. We have developed a low-temperature thermionic emission cathode that delivers 1 mA electron current at 80 mW power, making it possible to operate neutral wind-temperature experiments for the first time with powers less than 0.5 W. Advances in the ion optics of the energy-angle spectrometer enhance the energy resolution-aperture product more than a factor of 3 to enable energy resolutions of a few percent with large apertures. With these technology improvements it is now possible to obtain the full neutral wind vector, temperature and O/N2, density ratio once per second in a 250g/0.4W package with sensitivity up to about 500 km altitude in the thermosphere. We will describe the WTS as deployed in ANDE and show simulated data with the non-linear least squares analysis to illustrate expected performance of the WTS in the estimated errors in the three components of the wind, the temperature, and the relative densities.

  10. Emergence of structural patterns in neutral trophic networks.

    PubMed

    Canard, Elsa; Mouquet, Nicolas; Marescot, Lucile; Gaston, Kevin J; Gravel, Dominique; Mouillot, David

    2012-01-01

    Interaction networks are central elements of ecological systems and have very complex structures. Historically, much effort has focused on niche-mediated processes to explain these structures, while an emerging consensus posits that both niche and neutral mechanisms simultaneously shape many features of ecological communities. However, the study of interaction networks still lacks a comprehensive neutral theory. Here we present a neutral model of predator-prey interactions and analyze the structural characteristics of the simulated networks. We find that connectance values (complexity) and complexity-diversity relationships of neutral networks are close to those observed in empirical bipartite networks. High nestedness and low modularity values observed in neutral networks fall in the range of those from empirical antagonist bipartite networks. Our results suggest that, as an alternative to niche-mediated processes that induce incompatibility between species ("niche forbidden links"), neutral processes create "neutral forbidden links" due to uneven species abundance distributions and the low probability of interaction between rare species. Neutral trophic networks must be seen as the missing endpoint of a continuum from niche to purely stochastic approaches of community organization. PMID:22899987

  11. Characteristics of satellite accelerometer measurements of thermospheric neutral winds at high latitudes

    NASA Astrophysics Data System (ADS)

    Doornbos, E.; Ridley, A. J.; Cnossen, I.; Aruliah, A. L.; Foerster, M.

    2015-12-01

    Thermospheric neutral winds play an important part in the coupled thermosphere-ionosphere system at high latitudes. Neutral wind speeds have been derived from the CHAMP and GOCE satellites, which carried precise accelerometers in low Earth orbits. Due to the need to simultaneously determine thermosphere neutral density from the accelerometer in-track measurements, only information on the wind component in the cross-track direction, perpendicular to the flight direction can be derived. However, contrary to ground-based Fabry-Perot interferometer and scanning Doppler imager observations of the thermosphere wind, these satellite-based measurements provide equally distributed coverage over both hemispheres. The sampling of seasonal and local time variations depend on the precession rate of the satellite's orbital plane, with CHAMP covering about 28 cycles of 24-hour local solar time coverage, during its 10 year mission (2000-2010), while the near sun-synchronous orbit of GOCE resulted in a much more limited local time coverage ranging from 6:20 to 8:00 (am and pm), during a science mission duration of 4 years (2009-2013). For this study, the wind data from both CHAMP and GOCE have been analysed in terms of seasonal variations and geographic and geomagnetic local solar time and latitude coordinates, in order to make statistical comparisons for both the Northern and Southern polar areas. The wind data from both satellites were studied independently and in combination, in order to investigate how the strengths and weaknesses of the instruments and orbit parameters of these missions affect investigations of interhemispheric differences. Finally, the data have been compared with results from coupled ionosphere-thermosphere models and from ground-based FPI and SDI measurements.

  12. Neutral winds of the middle atmosphere observed at Arecibo using a Doppler Rayleigh lidar

    NASA Astrophysics Data System (ADS)

    Tepley, Craig A.

    1994-12-01

    We present our observations of the neutral winds of the tropical middle atmosphere that we made over a 2-year period at the Arecibo Observatory in Puerto Rico. The technique involves the use of a Doppler Rayleigh lidar that measures the spectral shift of the backscattered laser light up to 60 km altitude. We generally find the winds to have discernible patterns although we also observe a high degree of daily variability. We discuss these seasonal patterns and the daily variability and compare our measurements with balloon radiosonde measurements and with models of the tropical middle atmosphere.

  13. Neutral winds and electric fields in the dusk auroral oval. I - Measurements

    NASA Technical Reports Server (NTRS)

    Mikkelsen, I. S.; Jorgensen, T. S.; Kelley, M. C.; Larsen, M. F.; Pereira, E.; Vickrey, J.

    1981-01-01

    Two rockets carrying an upleg and downleg trimethyl aluminum chemical trail release and three barium cannisters were launched from Poker Flat, Alaska on Feb. 28, 1978 and Mar. 2, 1978 in order to study neutral winds and electric fields in the dusk auroral oval. Electric field measurements were also made with a radar system to supplement the barium cloud data. The barium cloud drifts on both days showed intense poleward electric fields in the subauroral region. The drifts were nearly latitude-independent and were equivalent to electric fields of 60 mV/m of February 2 and 40 mV/m on March 2. The data indicate that the Lorentz force and Joule heating had a strong influence on the observed neutral winds.

  14. Electric fields and neutral winds from monostatic incoherent scatter measurements by means of stochastic inversion

    NASA Astrophysics Data System (ADS)

    Nygrén, T.; Aikio, A. T.; Kuula, R.; Voiculescu, M.

    2011-05-01

    A new method utilizing stochastic inversion in determining the electric field and neutral wind from monostatic beam swing incoherent scatter measurements is described. The method consists of two stages. In the first stage, beam-aligned ion velocities from a chosen F region height interval and a set of subsequent beam directions are taken as measurements. The unknowns are the two electric field components and the field-aligned ion velocity profile. The solution gives the most probable values of the unknowns with error estimates. In the second stage, the measurements consist of beam-aligned ion velocities from the E region, and the electric fields given by the first inversion problem are also used as measurements. The number of applied beam directions may be greater than in the first inversion problem. This is a feasible approach since the neutral wind usually changes more slowly than the electric field. The solution of the second inversion problem gives the most probable values of the three neutral wind components. Results of the method are shown for 11 September 2005, when the European Incoherent Scatter (EISCAT) UHF radar was running in the CP2 experiment mode, which is a four-position 6 min monostatic cycle. In addition, from each beam direction a tristatic measurement at one F region range gate was made using two additional receivers. That allowed comparison between the monostatic and tristatic electric field results, which were in excellent agreement. The calculated neutral wind components were in good accordance with previous measurements during disturbed conditions from the same site.

  15. Neutral winds implied by electron content observations during the 7 March 1970 solar eclipse.

    NASA Technical Reports Server (NTRS)

    Almeida, O. G.; Waldman, H.; Da Rosa, A. V.

    1972-01-01

    Measurements of columnar electron content using geostationary satellite signals were made at several of our observatories throughout the U.S., during the 7 March 1970 solar eclipse. The ionospheric response to the solar eclipse was simulated in a computer. Discrepancies between observed and simulated electron content behaviors can be greatly reduced by assuming the existence of plausible neutral winds originated by the eclipse in the F-region heights.

  16. Modeling large wind farms in conventionally neutral atmospheric boundary layers under varying initial conditions

    NASA Astrophysics Data System (ADS)

    Allaerts, Dries; Meyers, Johan

    2014-05-01

    Atmospheric boundary layers (ABL) are frequently capped by an inversion layer limiting the entrainment rate and boundary layer growth. Commonly used analytical models state that the entrainment rate is inversely proportional to the inversion strength. The height of the inversion turns out to be a second important parameter. Conventionally neutral atmospheric boundary layers (CNBL) are ABLs with zero surface heat flux developing against a stratified free atmosphere. In this regime the inversion-filling process is merely driven by the downward heat flux at the inversion base. As a result, CNBLs are strongly dependent on the heating history of the boundary layer and strong inversions will fail to erode during the course of the day. In case of large wind farms, the power output of the farm inside a CNBL will depend on the height and strength of the inversion above the boundary layer. On the other hand, increased turbulence levels induced by wind farms may partially undermine the rigid lid effect of the capping inversion, enhance vertical entrainment of air into the farm, and increase boundary layer growth. A suite of large eddy simulations (LES) is performed to investigate the effect of the capping inversion on the conventionally neutral atmospheric boundary layer and on the wind farm performance under varying initial conditions. For these simulations our in-house pseudo-spectral LES code SP-Wind is used. The wind turbines are modelled using a non-rotating actuator disk method. In the absence of wind farms, we find that a decrease in inversion strength corresponds to a decrease in the geostrophic angle and an increase in entrainment rate and geostrophic drag. Placing the initial inversion base at higher altitudes further reduces the effect of the capping inversion on the boundary layer. The inversion can be fully neglected once it is situated above the equilibrium height that a truly neutral boundary layer would attain under the same external conditions such as

  17. An Innovative Low-Cost Program for Neutral Density and Wind Research With Small Satellites

    NASA Astrophysics Data System (ADS)

    Pilinski, M.; Forbes, J.; Grusin, M.; Koehler, C.; Palo, S.

    2007-12-01

    The Drag and Atmospheric Neutral Density Explorer (DANDE) is a 50 kg, spherical spacecraft being developed at the University of Colorado, Boulder. The goal of the DANDE mission is to provide an improved understanding of the satellite drag environment in the lower-thermosphere. To achieve this goal DANDE will measure in-situ neutral density, composition, and horizontal winds between 200 and 350 km. The relationship between composition, density and winds during disturbed atmospheric conditions and the relative effect on satellite drag will be addressed using DANDE measurements. DANDE is an extremely low-cost mission supported in part through the AFRL University Nanosatellite program. A low-cost design is achieved by using commercial technology and accelerometers as well as innovative miniaturized wind and atmospheric temperature spectrometer (WATS) developed at the Goddard Space Flight Center. As a secondary payload, this low-cost mission-model will provide a reproducible and reliable method for obtaining global space weather data on launches of opportunity. The result of commissioning such spacecraft into various orbits is continuity of space weather information related to the neutral thermosphere for both scientific analysis and now-casting purposes. Finally, DANDE will provide a way for empirical atmospheric models to be calibrated in near real-time while validating first-principles models through in-situ data. University of Colorado graduate and undergraduate students are designing and integrating the spacecraft to be delivered for environmental testing by summer of 2009.

  18. Geomagnetically conjugate observation of plasma bubbles and thermospheric neutral winds at low latitudes

    NASA Astrophysics Data System (ADS)

    Fukushima, D.; Shiokawa, K.; Otsuka, Y.; Nishioka, M.; Kubota, M.; Tsugawa, T.; Nagatsuma, T.; Komonjinda, S.; Yatini, C. Y.

    2015-03-01

    This is the first paper that reports simultaneous observations of zonal drift of plasma bubbles and the thermospheric neutral winds at geomagnetically conjugate points in both hemispheres. The plasma bubbles were observed in the 630 nm nighttime airglow images taken by using highly sensitive all-sky airglow imagers at Kototabang, Indonesia (geomagnetic latitude (MLAT): 10.0°S), and Chiang Mai, Thailand (MLAT: 8.9°N), which are nearly geomagnetically conjugate stations, for 7 h from 13 to 20 UT (from 20 to 03 LT) on 5 April 2011. The bubbles continuously propagated eastward with velocities of 100-125 m/s. The 630 nm images at Chiang Mai and those mapped to the conjugate point of Kototabang fit very well, which indicates that the observed plasma bubbles were geomagnetically connected. The eastward thermospheric neutral winds measured by two Fabry-Perot interferometers were 70-130 m/s at Kototabang and 50-90 m/s at Chiang Mai. We compared the observed plasma bubble drift velocity with the velocity calculated from the observed neutral winds and the model conductivity, to investigate the F region dynamo contribution to the bubble drift velocity. The estimated drift velocities were 60-90% of the observed velocities of the plasma bubbles, suggesting that most of the plasma bubble velocity can be explained by the F region dynamo effect.

  19. Large-scale wind turbine structures

    NASA Technical Reports Server (NTRS)

    Spera, David A.

    1988-01-01

    The purpose of this presentation is to show how structural technology was applied in the design of modern wind turbines, which were recently brought to an advanced stage of development as sources of renewable power. Wind turbine structures present many difficult problems because they are relatively slender and flexible; subject to vibration and aeroelastic instabilities; acted upon by loads which are often nondeterministic; operated continuously with little maintenance in all weather; and dominated by life-cycle cost considerations. Progress in horizontal-axis wind turbines (HAWT) development was paced by progress in the understanding of structural loads, modeling of structural dynamic response, and designing of innovative structural response. During the past 15 years a series of large HAWTs was developed. This has culminated in the recent completion of the world's largest operating wind turbine, the 3.2 MW Mod-5B power plane installed on the island of Oahu, Hawaii. Some of the applications of structures technology to wind turbine will be illustrated by referring to the Mod-5B design. First, a video overview will be presented to provide familiarization with the Mod-5B project and the important components of the wind turbine system. Next, the structural requirements for large-scale wind turbines will be discussed, emphasizing the difficult fatigue-life requirements. Finally, the procedures used to design the structure will be presented, including the use of the fracture mechanics approach for determining allowable fatigue stresses.

  20. Large-scale wind turbine structures

    NASA Astrophysics Data System (ADS)

    Spera, David A.

    1988-05-01

    The purpose of this presentation is to show how structural technology was applied in the design of modern wind turbines, which were recently brought to an advanced stage of development as sources of renewable power. Wind turbine structures present many difficult problems because they are relatively slender and flexible; subject to vibration and aeroelastic instabilities; acted upon by loads which are often nondeterministic; operated continuously with little maintenance in all weather; and dominated by life-cycle cost considerations. Progress in horizontal-axis wind turbines (HAWT) development was paced by progress in the understanding of structural loads, modeling of structural dynamic response, and designing of innovative structural response. During the past 15 years a series of large HAWTs was developed. This has culminated in the recent completion of the world's largest operating wind turbine, the 3.2 MW Mod-5B power plane installed on the island of Oahu, Hawaii. Some of the applications of structures technology to wind turbine will be illustrated by referring to the Mod-5B design. First, a video overview will be presented to provide familiarization with the Mod-5B project and the important components of the wind turbine system. Next, the structural requirements for large-scale wind turbines will be discussed, emphasizing the difficult fatigue-life requirements. Finally, the procedures used to design the structure will be presented, including the use of the fracture mechanics approach for determining allowable fatigue stresses.

  1. Jupiter's winds and Arnol'd's second stability theorem: Slowly moving waves and neutral stability

    NASA Technical Reports Server (NTRS)

    Stamp, Andrew P.; Dowling, Timothy E.

    1993-01-01

    Since the Voyager encounters in 1979, it has been known that Jupiter's cloud-top zonal winds violate the barotropic stability criterion. A vortex-tube stretching analysis of the Voyager wind data indicates that the more general Charney-Stern stability criterion is also violated. On the other hand, the zonal winds determined by tracking cloud features in Hubble Space Telescope images taken in 1991 precisely match the zonal winds determined by tracking cloud features in Voyager images, and it is hard to understand how a complicated zonal wind profile like Jupiter's could be unstable and yet not change at all in 12 years. In fact, there are at least two unknown ways to violate the Charney-Stern stability criterion and still have a stable flow. The better known of these is called Fjortoft's theorem, or Arnol'd's 1st theorem for the case of large-amplitude perturbations. Although the Fjortoft-Arnol'd theorem has been extended from the quasi-geostrophic equations to the primitive equations, the basic requirement that the potential vorticity be an increasing function of streamfunction is opposite to the case found in Jupiter, where the Voyager data indicate that the potential vorticity is a decreasing function of streamfunction. But this second case is precisely that which is covered by Arnol'd's 2nd stability theorem. In fact, the Voyager data suggest that Jupiter's zonal winds are neutrally stable with respect to Arnol'd's 2nd stability theorem. Here, we analyze the linear stability problem of a one-parameter family of sinusoidal zonal wind profiles that are close to neutral stability with respect to Arnol'd's 2nd stability theorem. We find numerically that the most unstable mode is always stationary, which may help to explain the slowly moving mode 10 waves observed on Jupiter. We find that violation of Arnol'd's 2nd stability theorem is both necessary and sufficient for instability of sinusoidal profiles. However, there appears to be no simple extension of Arnol'd's 2

  2. Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1

    SciTech Connect

    Kong, Leopold; Giang, Erick; Robbins, Justin B.; Stanfield, Robyn L.; Burton, Dennis R.; Wilson, Ian A.; Law, Mansun

    2012-10-29

    Hepatitis C virus (HCV) infects more than 2% of the global population and is a leading cause of liver cirrhosis, hepatocellular carcinoma, and end-stage liver diseases. Circulating HCV is genetically diverse, and therefore a broadly effective vaccine must target conserved T- and B-cell epitopes of the virus. Human mAb HCV1 has broad neutralizing activity against HCV isolates from at least four major genotypes and protects in the chimpanzee model from primary HCV challenge. The antibody targets a conserved antigenic site (residues 412-423) on the virus E2 envelope glycoprotein. Two crystal structures of HCV1 Fab in complex with an epitope peptide at 1.8-{angstrom} resolution reveal that the epitope is a {beta}-hairpin displaying a hydrophilic face and a hydrophobic face on opposing sides of the hairpin. The antibody predominantly interacts with E2 residues Leu{sup 413} and Trp{sup 420} on the hydrophobic face of the epitope, thus providing an explanation for how HCV isolates bearing mutations at Asn{sup 415} on the same binding face escape neutralization by this antibody. The results provide structural information for a neutralizing epitope on the HCV E2 glycoprotein and should help guide rational design of HCV immunogens to elicit similar broadly neutralizing antibodies through vaccination.

  3. Structural analysis considerations for wind turbine blades

    NASA Technical Reports Server (NTRS)

    Spera, D. A.

    1979-01-01

    Approaches to the structural analysis of wind turbine blade designs are reviewed. Specifications and materials data are discussed along with the analysis of vibrations, loads, stresses, and failure modes.

  4. Structural features of neutral and cationic cyclams

    NASA Astrophysics Data System (ADS)

    Alves, Luis G.; Duarte, M. Teresa; Martins, Ana M.

    2015-10-01

    Dicationic compounds of general formula [1,8-R2-1,4,8,11-tetraazatricyclo[9.3.1.14,8]hexadecane]X2, where R = H, Me or Bn' and X is a halogen counterion were obtained by reactions of 1,4,8,11-tetraazatricyclo[9.3.1.14,8]hexadecane with different electrophiles. The solid-state molecular structures of the compounds reveal that the hydrogen, methyl or benzyl groups are located on the nitrogen atoms that are not only the less sterically hindered but also have the electron lone pair pointing out of the macrocycle backbone. In all compounds it is observed a bond shortening between the N-Caminal and the two other C-N bonds that may be attributed to an inductive effect. These compounds afford the corresponding trans-N,N'-disubstituted cyclams upon hydrolysis in basic medium.

  5. Wind velocity measurements in the neutral boundary layer above hilly prairie

    NASA Technical Reports Server (NTRS)

    Sugita, Michiaki; Brutsaert, Wilfried

    1990-01-01

    The Flint Hills region in eastern Kansas is characterized by a strongly dissected rolling to hilly terrain with an average about 25 m of relief between steep ridges and valleys, and with ridges typically separated by distances of the order of 600 m. Intensive radiosonde observations during summer and fall of 1987 allowed the determination of some aspects of the wind regime in the region. For an assumed ground-surface reference of 330 m above sea level (asl), analysis of neutral profiles yielded a value z(0) of about 1.05 m, approximately. Good agreement was obtained between the values of friction velocity derived from wind profiles and values determined independently from the corresponding humidity profiles.

  6. Optimising estimates of mesospheric neutral wind using the TIGER SuperDARN radar

    NASA Astrophysics Data System (ADS)

    Matthews, D. M.; Parkinson, M. L.; Dyson, P. L.; Devlin, J. C.

    2006-01-01

    Super Dual Auroral Radar Network (SuperDARN) HF backscatter radars scan 16 beam directions over a field of view of ˜52°. In the common mode of operation, data is collected using 45-km range gates and 7-s integrations on each beam. Application of a beam-swinging algorithm permits mesospheric neutral winds to be estimated from the line-of-sight (LOS) Doppler velocity of meteor echoes detected at near ranges (<600 km). Larger meteor echo detection rates better constrain the solutions and thereby increase the accuracy of wind estimates. Greater rates also lead to wind estimates with better time and height resolution. In this study, meteor echo detection rates were increased by running dedicated radar control programs on the Tasman Geospace Environment Radar (TIGER) Tasmania radar (147.2°E, 43.4°S). This involved the use of shorter 15-km range gates and 2-s integration times. The Doppler characteristics of different echo types at meteor echo ranges were identified. The echoes were then filtered according to these characteristics, and their suitability for estimating neutral winds investigated. One echo type was clearly of ionospheric origin, forming thin, continuous traces decreasing in group range from ˜1200 to ˜300 km before midnight. These "descending plasma streams" (DPS) merged into and contaminated the meteor scatter observed by TIGER. However, they will be less of a problem for the planned network of "storm time" SuperDARN radars to be deployed at mid-latitudes for the study of major substorms and storms which occur less frequently.

  7. Watershed Scale Shear Stress From Tethersonde Wind Profile Measurements Under Near Neutral and Unstable Atmospheric Stability

    NASA Astrophysics Data System (ADS)

    Parlange, M. B.; Katul, G. G.

    1995-04-01

    Mean wind speed profiles were measured in the atmospheric surface layer, using a tethersonde system, above the Ojai Valley Watershed in southern California. The valley is mainly planted with mature avocado and orange trees. The surface shear stress and latent and sensible heat fluxes were measured above the trees which are up to 9 m in height. Near-neutral wind speed profile measurements allowed the determination of the watershed surface roughness (z0 = 1.4 m) and the momentum displacement height (d0 = 7.0 m). The wind speed measurements obtained under unstable atmospheric stability were analyzed using Monin-Obukhov similarity theory. New stability correction functions proposed based on theory and experiments of Kader-Yaglom as well as the now classic Businger-Dyer type functions were tested. The watershed shear stress values calculated using the surface layer wind speed profiles with the new Monin-Obukhov stability functions were found to be improved in comparison with the values obtained with the Businger-Dyer functions under strongly unstable stability conditions. The Monin-Obukhov model with the Businger-Dyer stability correction function underpredicted the momentum flux by 25% under strongly unstable stability conditions, while the new Kader-Yaglom formulation compared well on average (R2 = 0.77) with the surface eddy correlation measurements for all atmospheric stability conditions. The unstable 100-m drag coefficient was found to be u*2/V1002 = 0.0182.

  8. Flare response to the thermospheric diurnal neutral wind measured by the OMTIs' Fabry-Perot Interferometers

    NASA Astrophysics Data System (ADS)

    Yatagai, A. I.; Shiokawa, K.

    2014-12-01

    This research aims at investigating the influence of flare events to the thermospheric tidal wind in order to grasp the EUV effect of the solar activity to upper atmospheric circulation. The neutral wind at about 250km level observed with the 630nm airglow by Fabry-Perot interferometers of the Optical Mesosphere Thermosphere Imagers (OMTIs) is analyzed. We used the 15-minutes interval data at Shigaraki for the year 2000 to 2013. 10953 of 59881 samples became usable after a quality control. We used the flare list issued by NOAA extracted from the X-rays from GOES satellites. There are 131 of X-class flares and 1510 of M-class flares during the 14 years. However, the number of samples to which effective observation of FPI is carried out at the flare peak time was 51. Before composite of the wind at the time of solar flare (so-called superimposed epoc analysis), monthly climatological wind is made. First, the valid data of every month were averaged in every 15 minutes for 9-21 UTC, then, three months data were averaged. Further, the 15-minutes temporal variation data was smoothed with a Gaussian filter. From the 51 sample data containing the flare peak time, the zonal wind (Ve) and the meridional wind (Vn) were composed after deducted the above mentioned climatology with a flare peak time as the starting point (t=0). Supposing the atmosphere on the daytime side expands under the influence of the flare temporarily and the advection current to the night side is strengthened, the eastward (westward) wind should be strengthened before (after) midnight. Since the influence of the increment of the air expansion in mid-night may have been offset, the samples which flare occurs before midnight (39 samples) were composited. As a result, as for Ve, significant change of eastward wind to westward wind compared to the standard deviation is observed after 3hrs and a half after solar flare occurred, while as for Vn, significant enhancement of southward component is observed after 4

  9. Energetic Turbulence Structures in the Wake of Model Wind Turbines

    NASA Astrophysics Data System (ADS)

    Sheng, Jian; Mehdi, Faraz; Chamorro, Leonardo P.

    2013-11-01

    Wind turbine wakes contain complex and energetic flow structures. Characterizing the near-wake field is critical to assess flow-structure interactions and evaluate asymmetric loadings that trigger premature structural failure. Although the turbulence flow structure in the far-wake region is important in the wind farm design, an integrated characterization of the entire wake flow would provide clearer mechanistic view on other phenomena such wake meandering and unsteady interactions with the blades of downwind turbines. High-speed Particle Image Velocimetry (PIV) is carried out over a model wind turbine in a neutrally stratified boundary layer flow. The measurements are made at consecutive locations ranging from three rotor diameters upstream to twelve rotor diameters downstream of the unit. Vortical structures within the wake including tip, root and hub vortices are identified and followed as they advect downstream. The evolution of these dominant near-wake flow structures are quantified and provide us a better understanding of interactions between turbine wake and boundary layer. The spatial distribution of the mean and fluctuating velocity, as well as energy spectrum and turbulent kinetic budget are also discussed.

  10. Low-latitude thermospheric neutral winds determined from AE-E measurements of the 6300-A nightglow at solar maximum

    NASA Technical Reports Server (NTRS)

    Burrage, M. D.; Abreu, V. J.; Fesen, C. G.

    1990-01-01

    Atmosphere Explorer E (AE-E) measurements of the O(1D) 6300-A emission in the nighttime equatorial thermosphere are used to infer the height of the F2 layer peak as a function of latitude and local time. The investigation is conducted both for northern hemisphere winter solstice and for spring equinox, under solar maximum conditions. The layer heights are used to derive magnetic meridional components of the transequatorial neutral wind, in conjunction with the MSIS-86 model and previous Jicamarca incoherent scatter measurements of the zonal electric field. The AE-E wind estimates indicate a predominant summer to winter flow for the winter solstice case. Comparisons are made with the empirical horizontal wind model HWM87 and with winds generated by the thermospheric general circulation model. The model predictions and experimental results are generally in good agreement, confirming the applicability of visible airglow data to studies of the global neutral wind pattern.

  11. The interaction between the solar wind and the heterogeneous neutral gas coma of comet 67P/Churyumov-Gerasimenko

    NASA Astrophysics Data System (ADS)

    Rubin, Martin; Toth, Gabor; Tenishev, Valeriy; Fougere, Nicolas; Huang, Zhenguang

    2016-07-01

    Comets are surrounded by an extended gas and dust coma. Neutral particles are continuously ionized by solar irradiation and then picked-up by the solar wind. This leads to a complex interaction between the neutral gas coma and the solar wind, which changes over the course of the comet's orbit around the Sun. The European Space Agency's Rosetta spacecraft has been in orbit around comet 67P/Churyumov-Gerasimenko since August 2014. Rosetta carries several instruments to investigate the comet's nucleus and surrounding neutral gas coma and plasma. Part of the payload is the Rosetta Orbiter Spectrometer for Ion and Neutral Analysis (ROSINA) that consists of two mass spectrometers and a pressure sensor. ROSINA was designed to measure the neutral gas abundance and composition and low energy ions in the coma in situ. ROSINA observations have shown that the coma is very heterogeneous both in total density and composition of the neutral gas. This heterogeneity is driven in large part by the complex shape of the nucleus and the varying illumination conditions associated with the comet's rotation. In this presentation we will show the time-dependent distribution of the major volatiles around the comet constrained by ROSINA observations. Furthermore we will investigate the impact of the highly non-symmetric neutral gas coma on the interaction of the solar wind with the comet.

  12. Structure and Design of Broadly-Neutralizing Antibodies Against HIV

    PubMed Central

    Ryu, Seong Eon; Hendrickson, Wayne A.

    2012-01-01

    Since the discovery more than 30 years ago of human immunodeficiency virus (HIV) as the causative agent of the deadly disease, acquired immune deficiency disease (AIDS), there have been no efficient vaccines against the virus. For the infection of the virus, the HIV surface glycoprotein gp120 first recognizes the CD4 receptor on the target helper T-cell, which initiates HIV fusion with the target cell and, if unchecked, leads to destruction of the patient’s immune system. Despite the difficulty of developing appropriate immune responses in HIV-infected individuals, patient sera often contain antibodies that have broad neutralization activity, indicating the possibility of immunological treatment and prevention. Recently, through extensive structural studies of neutralizing antibodies of HIV in complex with gp120, the critical mechanisms of broad neutralization against HIV have been elucidated. Based on these discoveries, the structure-aided designs of antibodies and novel scaffolds were performed to create extremely potent neutralizing antibodies against HIV. These new discoveries and advances shed light on the road to development of efficient immunological therapies against AIDS. PMID:22736269

  13. Analysis of Solar Wind Samples Returned by Genesis Using Laser Post Ionization Secondary Neutral Mass Spectrometry

    NASA Astrophysics Data System (ADS)

    Veryovkin, I. V.; Calaway, W. F.; Tripa, C. E.; Pellin, M. J.; Burnett, D. S.

    2005-12-01

    A new secondary neutral mass spectrometry (SNMS) instrument implementing laser post ionization (LPI) of ion sputtered and laser desorbed neutral species has been developed and constructed for the specific purpose of quantitative analysis of metallic elements at ultra trace levels in solar wind collector samples returned to Earth by the Genesis Discovery mission. The first LPI SNMS measurements are focusing on determining Al, Ca, Cr, and Mg in these samples. These measurements provide the first concentration and isotopic abundances determinations for several key metallic elements and also elucidate possible fractionation effects between the photosphere and the solar wind compositions. It is now documented that Genesis samples suffered surface contamination both during flight and during the breach of the Sample Return Capsule when it crashed. Since accurate quantitative analysis is compromised by sample contamination, several features have been built into the new LPI SNMS instrument to mitigate this difficulty. A normally-incident, low-energy (<500 eV) ion beam combined with a keV energy ion beam and a desorbing laser beam (both microfocused) enables dual beam analyses. The low-energy ion beam can be used to remove surface contaminant by sputtering with minimum ion beam mixing. This low-energy beam also will be used to perform ion beam milling, while either the microfocused ion or laser beam probes the solar wind elemental compositions as a function of sample depth. Because of the high depth resolution of dual beam analyses, such depth profiles clearly distinguish between surface contaminants and solar wind implanted atoms. In addition, in-situ optical and electron beam imaging for observing and avoiding particulates and scratches on solar wind sample surfaces is incorporated in the new LPI SNMS instrument to further reduce quantification problems. The current status of instrument tests and analyses will be presented. This work is supported by the U. S. Department of

  14. On the characterization of coherent structures within a neutrally-stratified atmospheric boundary layer

    NASA Astrophysics Data System (ADS)

    Rosi, Giuseppe; Le Bastide, Benen; Gaebler, Julia; Kinzel, Matias; Rival, David

    2012-11-01

    Up to this point, a clear characterization of wind turbulence and extreme gust events through experimentation has frustrated countless researchers. The statistical analysis of fluctuating components has been exhausted while the conditional analysis of extreme events, though insightful, often results in constricted conclusions that cannot be bridged from study to study. Thus the current study shifts towards an understanding of the fundamental turbulent flow structures within a neutrally-stratified atmospheric boundary layer. Two approaches to characterize coherent wind structures are presented. The first approach identifies hairpin-vortex heads by correlating three-dimensional, fluctuating data from two high-speed anemometers situated at 40m and 50m heights on a wind mast. The model assumes that a hairpin-vortex head can be approximated as a transverse vortex with a Vatistas viscous core of assumed radius when the hairpin-vortex head impinges onto the two anemometers. The second approach employs large-scale particle tracking velocimetry to follow seeded bubbles next to the wind mast. The results obtained with both approaches are then compared, and the advantages and shortcomings of each method are discussed.

  15. Coronal structure and the solar wind

    NASA Technical Reports Server (NTRS)

    Roelof, E. C.

    1974-01-01

    Aspects concerning the open coronal structure and geomagnetic disturbances are considered along with the general coronal emission characteristics and relations between the open coronal structure and the interplanetary field. The nonstatistical indicators of coronal structure are examined and questions are investigated regarding the accuracy obtained in the determination of the emission latitude and longitude in the high corona for plasma, fields, and particles. Attention is given to the problem of particle population organization by low-coronal neutral line structures in the absence of a high coronal polarity structure.

  16. Thermospheric neutral wind profile in moonlit midnight by Lithium release experiments in Japan

    NASA Astrophysics Data System (ADS)

    Yamamoto, M. Y.; Watanabe, S.; Abe, T.; Kakinami, Y.; Habu, H.; Yamamoto, M.

    2015-12-01

    Neutral wind profiles were observed in lower thermosphere at about between 90 km and 130 km altitude by using resonance scattering light of moonlit Lithium (Li) vapor released from sounding rockets in midnight (with almost full-moon condition) in 2013 in Japan. As a target of the Daytime Dynamo campaign, Li release experiment was operated at Wallops Flight Facility (WFF) of NASA, U.S.A. in July, 2013 (Pfaff et al., 2015, this meeting), while the same kind of rocket-ground observation campaign in midnight was carried out by using S-520-27/S-310-42 sounding rockets in Uchinoura Space Center (USC) of JAXA, Kagoshima, Japan, also in July 2013.Since imaging signal-to-noise (S/N) condition of the experiment was so severe, we conducted to apply airborne observation for imaging the faint moonlit Li tracers so as to reduce the illuminating intensity of the background skies as an order of magnitude. Two independent methods for calculating the wind profile were applied to the Lithium emission image sequences successfully obtained by the airborne imaging by special Li imagers aboard the airplanes in order to derive precise information of Li tracers motion under the condition of single observation site on a moving aircraft along its flight path at about 12 km altitude in lower stratosphere. Slight attitude-feedback motion of the aircraft's 3-axes attitude changes (rolling, yawing and pitching) was considered for obtaining precise coordinates on each snapshot. Another approach is giving a simple mathematic function for wind profile to resolve the shape displacement of the imaged Li tracers. As a result, a wind profile in moonlit thermosphere was calculated in a range up to about 150 m/s with some fluctuated parts possibly disturbed by wind shears. In the same experiment, another sounding rocket S-310-42 with a TMA canister was also launched from USC/JAXA at about 1 hour before the rocket with carrying the Lithium canisters, thus, we can derive the other 2 profiles determined by

  17. Atmospheric response in aurora experiment: Observations of E and F region neutral winds in a region of postmidnight diffuse aurora

    NASA Technical Reports Server (NTRS)

    Larsen, M. F.; Marshall, T. R.; Mikkelsen, I. S.; Emery, B. A.; Christensen, A.; Kayser, D.; Hecht, J.; Lyons, L.; Walterscheid, R.

    1995-01-01

    The goal of the Atmospheric Response in Aurora (ARIA) experiment carried out at Poker Flat, Alaska, on March 3, 1992, was to determine the response of the neutral atmosphere to the long-lived, large-scale forcing that is characteristic of the diffuse aurora in the post midnight sector. A combination of chemical release rocket wind measurements, instrumented rocket composition measurements, and ground-based optical measurements were used to characterize the response of the neutral atmosphere. The rocket measurements were made at the end of a 90-min period of strong Joule heating. We focus on the neutral wind measurements made with the rocket. The forcing was determined by running the assimilated mapping of ionospheric electrodynamics (AMIE) analysis procedure developed at the National Center for Atmospheric Research. The winds expected at the latitude and longitude of the experiment were calculated using the spectral thermospheric general circulation model developed at the Danish Meteorological Institute. Comparisons of the observations and the model suggest that the neutral winds responded strongly in two height ranges. An eastward wind perturbation of approximately 100 m/s developed between 140 and 200 km altitude with a peak near 160 km. A southwestward wind with peak magnitude of approximately 150 m/s developed near 115 km altitude. The large amplitude winds at the lower altitude are particularly surprising. They appear to be associated with the upward propagating semidiurnal tide. However, the amplitude is much larger than predicted by any of the tidal models, and the shear found just below the peak in the winds was nominally unstable with a Richardson number of approximately 0.08.

  18. Midnight ionosphere collapse at Arecibo and its relationship to the neutral wind, electric field, and ambipolar diffusion

    NASA Astrophysics Data System (ADS)

    Gong, Yun; Zhou, Qihou; Zhang, Shaodong; Aponte, Nestor; Sulzer, Michael; Gonzalez, Sixto

    2012-08-01

    We report the analysis of "midnight collapse," a large drop in the F-layer peak height (HmF2) around midnight, observed at Arecibo during Jan. 14-22, 2010. During the nine nights of observations, the first four nights (Jan. 14-17) exhibited modest drops in HmF2 while the last five nights (Jan. 18-22) showed more severe drops. We examine the roles played by the meridional wind, electric field, and ambipolar diffusion in driving the vertical ion motion. The collapse process can be classified into three stages: preconditioning, initial descent, and sustained descent. Severe collapses occur when HmF2 is preconditioned high prior to the collapse. Ambipolar diffusion is most important during the initial descent. Neutral wind and electric field are responsible for sustaining the collapse. During Jan. 18-22, HmF2 was pushed high by the neutral wind before the collapse started. Neutral wind and electric field were in phase during the sustained severe collapses. The diurnal tide of the meridional wind provided the general condition for the collapses. The terdiurnal tide was most important to cause the difference between the two periods in our observation. Previous studies largely emphasized meridional wind being the dominant mechanism causing midnight collapse. Our study suggests that electric field and ambipolar diffusion also play an important role and the former can be the most dominant factor in some cases.

  19. EFFECT OF SOLAR CHROMOSPHERIC NEUTRALS ON EQUILIBRIUM FIELD STRUCTURES

    SciTech Connect

    Arber, T. D.; Botha, G. J. J.; Brady, C. S. E-mail: G.J.J.Botha@warwick.ac.u

    2009-11-10

    Solar coronal equilibrium fields are often constructed by nonlinear force-free field (NLFFF) extrapolation from photospheric magnetograms. It is well known that the photospheric field is not force-free and the correct lower boundary for NLFFF construction ought to be the top of the chromosphere. To compensate for this, pre-filtering algorithms are often applied to the photospheric data to remove the non-force-free components. Such pre-filtering models, while physically constrained, do not address the mechanisms that may be responsible for the field becoming force-free. The chromospheric field can change through, for example, field expansion due to gravitational stratification, reconnection, or flux emergence. In this paper, we study and quantify the effect of the chromospheric neutrals on equilibrium field structures. It is shown that, depending on the degree to which the photospheric field is not force-free, the chromosphere will change the structure of the equilibrium field. This is quantified to give an estimate of the change in alpha profiles one might expect due to neutrals in the chromosphere. Simple scaling of the decay time of non-force-free components of the magnetic field due to chromospheric neutrals is also derived. This is used to quantify the rate at which, or equivalent at which height, the chromosphere is expected to become force-free.

  20. Highly Structured Wind in Vela X-1

    NASA Technical Reports Server (NTRS)

    Kreykenbohm, Ingo; Wilms, Joern; Kretschmar, Peter; Torrejon, Jose Miguel; Pottschmidt, Katja; Hanke, Manfred; Santangelo, Andrea; Ferrigno, Carlo; Staubert, Ruediger

    2008-01-01

    We present an in-depth analysis of the spectral and temporal behavior of a long almost uninterrupted INTEGRAL observation of Vela X-1 in Nov/Dec 2003. In addition to an already high activity level, Vela X-1 exhibited several very intense flares with a maximum intensity of more than 5 Crab in the 20 40 keV band. Furthermore Vela X-1 exhibited several off states where the source became undetectable with ISGRI. We interpret flares and off states as being due to the strongly structured wind of the optical companion: when Vela X-1 encounters a cavity in the wind with strongly reduced density, the flux will drop, thus potentially triggering the onset of the propeller effect which inhibits further accretion, thus giving rise to the off states. The required drop in density to trigger the propeller effect in Vela X-1 is of the same order as predicted by theoretical papers for the densities in the OB star winds. The same structured wind can give rise to the giant flares when Vela X-1 encounters a dense blob in the wind. Further temporal analysis revealed that a short lived QPO with a period of 6800 sec is present. The part of the light curve during which the QPO is present is very close to the off states and just following a high intensity state, thus showing that all these phenomena are related.

  1. Structure and dynamics of supercooled water in neutral confinements

    NASA Astrophysics Data System (ADS)

    Klameth, F.; Vogel, M.

    2013-04-01

    We perform molecular dynamics simulations to study the structure and dynamics of liquid water in neutral nanopores, which are generated by pinning a suitable subset of water molecules in an equilibrium configuration of a bulk system. It is found that such neutral confinement does not disturb the structure of water, in particular, the local tetrahedral order, while it imposes a pronounced spatial inhomogeneity on the dynamics of water. Specifically, when the pore wall is approached, hopping motion sets in and water dynamics slows down. We show that the logarithm of the correlation time is an exponential function of the distance to the wall, indicating a tremendous gradient of water mobility across the confinement. Upon cooling, the length scale associated with this exponential distance dependence and, thus, the range of the wall effect increases, at least down to the critical temperature of mode coupling theory, Tc. Also, the temperature dependence of water dynamics varies across the pore, i.e., fragility is high in the pore center, while it is low near the pore wall. Due to all these effects, time-temperature superposition is violated. Our observations for a neutral confinement reveal that specific interactions at hydrophilic or hydrophobic walls are not the main cause of spatially inhomogeneous dynamics of confined water. In view of similarities with the behavior of Lennard-Jones liquids in neutral confinements, one may rather speculate that the effects observed for confined water are general and result from the existence of a static contribution to the energy landscape, which is imprinted by an immobile environment.

  2. Imaging the Heliosphere Using Neutral Atoms from Solar Wind Energy Down to 15 eV

    NASA Astrophysics Data System (ADS)

    Galli, A.; Wurz, P.; Fuselier, S. A.; McComas, D. J.; Bzowski, M.; Sokół, J. M.; Kubiak, M. A.; Möbius, E.

    2014-11-01

    We study the spatial and temporal distribution of hydrogen energetic neutral atoms (ENAs) from the heliosheath observed with the IBEX-Lo sensor of the Interstellar Boundary EXplorer (IBEX) from solar wind energies down to the lowest available energy (15 eV). All available IBEX-Lo data from 2009 January until 2013 June were included. The sky regions imaged when the spacecraft was outside of Earth's magnetosphere and when the Earth was moving toward the direction of observation offer a sufficient signal-to-noise ratio even at very low energies. We find that the ENA ribbon—a 20° wide region of high ENA intensities—is most prominent at solar wind energies whereas it fades at lower energies. The maximum emission in the ribbon is located near the poles for 2 keV and closer to the ecliptic plane for energies below 1 keV. This shift is an evidence that the ENA ribbon originates from the solar wind. Below 0.1 keV, the ribbon can no longer be identified against the globally distributed ENA signal. The ENA measurements in the downwind direction are affected by magnetospheric contamination below 0.5 keV, but a region of very low ENA intensities can be identified from 0.1 keV to 2 keV. The energy spectra of heliospheric ENAs follow a uniform power law down to 0.1 keV. Below this energy, they seem to become flatter, which is consistent with predictions. Due to the subtraction of local background, the ENA intensities measured with IBEX agree with the upper limit derived from Lyα observations.

  3. Imaging the heliosphere using neutral atoms from solar wind energy down to 15 eV

    SciTech Connect

    Galli, A.; Wurz, P.; Fuselier, S. A.; McComas, D. J.; Bzowski, M.; Sokół, J. M.; Kubiak, M. A.; Möbius, E.

    2014-11-20

    We study the spatial and temporal distribution of hydrogen energetic neutral atoms (ENAs) from the heliosheath observed with the IBEX-Lo sensor of the Interstellar Boundary EXplorer (IBEX) from solar wind energies down to the lowest available energy (15 eV). All available IBEX-Lo data from 2009 January until 2013 June were included. The sky regions imaged when the spacecraft was outside of Earth's magnetosphere and when the Earth was moving toward the direction of observation offer a sufficient signal-to-noise ratio even at very low energies. We find that the ENA ribbon—a 20° wide region of high ENA intensities—is most prominent at solar wind energies whereas it fades at lower energies. The maximum emission in the ribbon is located near the poles for 2 keV and closer to the ecliptic plane for energies below 1 keV. This shift is an evidence that the ENA ribbon originates from the solar wind. Below 0.1 keV, the ribbon can no longer be identified against the globally distributed ENA signal. The ENA measurements in the downwind direction are affected by magnetospheric contamination below 0.5 keV, but a region of very low ENA intensities can be identified from 0.1 keV to 2 keV. The energy spectra of heliospheric ENAs follow a uniform power law down to 0.1 keV. Below this energy, they seem to become flatter, which is consistent with predictions. Due to the subtraction of local background, the ENA intensities measured with IBEX agree with the upper limit derived from Lyα observations.

  4. Structural basis for the antibody neutralization of Herpes simplex virus

    SciTech Connect

    Lee, Cheng-Chung; Lin, Li-Ling; Chan, Woan-Eng; Ko, Tzu-Ping; Lai, Jiann-Shiun; Wang, Andrew H.-J.

    2013-10-01

    The gD–E317-Fab complex crystal revealed the conformational epitope of human mAb E317 on HSV gD, providing a molecular basis for understanding the viral neutralization mechanism. Glycoprotein D (gD) of Herpes simplex virus (HSV) binds to a host cell surface receptor, which is required to trigger membrane fusion for virion entry into the host cell. gD has become a validated anti-HSV target for therapeutic antibody development. The highly inhibitory human monoclonal antibody E317 (mAb E317) was previously raised against HSV gD for viral neutralization. To understand the structural basis of antibody neutralization, crystals of the gD ectodomain bound to the E317 Fab domain were obtained. The structure of the complex reveals that E317 interacts with gD mainly through the heavy chain, which covers a large area for epitope recognition on gD, with a flexible N-terminal and C-terminal conformation. The epitope core structure maps to the external surface of gD, corresponding to the binding sites of two receptors, herpesvirus entry mediator (HVEM) and nectin-1, which mediate HSV infection. E317 directly recognizes the gD–nectin-1 interface and occludes the HVEM contact site of gD to block its binding to either receptor. The binding of E317 to gD also prohibits the formation of the N-terminal hairpin of gD for HVEM recognition. The major E317-binding site on gD overlaps with either the nectin-1-binding residues or the neutralizing antigenic sites identified thus far (Tyr38, Asp215, Arg222 and Phe223). The epitopes of gD for E317 binding are highly conserved between two types of human herpesvirus (HSV-1 and HSV-2). This study enables the virus-neutralizing epitopes to be correlated with the receptor-binding regions. The results further strengthen the previously demonstrated therapeutic and diagnostic potential of the E317 antibody.

  5. The collapse of the midnight ionosphere and behavior of meridional neutral winds at Townsville over a full solar cycle

    NASA Astrophysics Data System (ADS)

    Dandenault, P. B.; Richards, P. G.

    2015-11-01

    This paper investigates the causes of the sudden descent (midnight collapse) of the ionosphere at Townsville, Australia, during the equinox periods of years between 1970 and 1980. The collapse of hmF2 at midnight is found to occur on 89% of the 330 equinox nights that are investigated, and the mean magnitude of the midnight collapse is 84 km in the March equinox periods and 99 km in the September equinox periods. Observations of hmF2 are used to determine equivalent meridional neutral winds using a first principles physics model. Harmonic analysis of these derived winds reveals the existence of significant diurnal (24 h), semidiurnal (12 h), and terdiurnal (8 h) tidal components. The contribution of wind harmonics to the midnight collapse is determined by band-pass filtering the winds to only allow certain tides and then modeling their effect on hmF2 near midnight. The results indicate that the diurnal, semidiurnal, and terdiurnal components of the meridional neutral wind all play a significant role at various times, but the effect of the 6 h wind component is minimal. The spectral analysis also reveals that the terdiurnal wind component becomes dominant during solar maximum. Electric fields do not appear to be responsible for the midnight hmF2 collapse because it is seldom seen at the near-conjugate station of Akita, Japan.

  6. Structure of gentlyase, the neutral metalloprotease of Paenibacillus polymyxa.

    PubMed

    Ruf, Armin; Stihle, Martine; Benz, Jörg; Schmidt, Manfred; Sobek, Harald

    2013-01-01

    Gentlyase is a bacterial extracellular metalloprotease that is widely applied in cell culture and for tissue dissociation and that belongs to the family of thermolysin-like proteases. The structure of thermolysin has been known since 1972 and that of Bacillus cereus neutral protease since 1992. However, the structure determination of other Bacillus neutral proteases has been hindered by their tendency to cannibalistic autolysis. High calcium conditions that allow the concentration and crystallization of the active Gentlyase metalloprotease without autoproteolysis were identified using thermal fluorescent shift assays. X-ray structures of the protease were solved in the absence and in the presence of the inhibitor phosphoramidon at 1.59 and 1.76 Å resolution, respectively. No domain movement was observed upon inhibitor binding, although such movement is thought to be a general feature of the thermolysin-like protease family. Further analysis of the structure shows that the observed calcium dependency of Gentlyase stability may arise from a partly degenerated calcium site Ca1-2 and a deletion near site Ca3. PMID:23275160

  7. Frequency domain modelling of wind turbine structures

    SciTech Connect

    Soerensen, P.; Larsen, G.C.; Christensen, C.J.

    1995-09-01

    The present paper describes a frequency domain model of the structure of an operating horizontal axis wind turbine. The frequency domain model is implemented along with an analogous time domain modeling the Risoe PC code Design Basis 2, and a more detailed description of the model is offered in a Risoe report by Soerensen (1994). The structure of an operating wind turbine is affected by essential non-linearities between structural variables on blades and tower respectively. These non-linearities are caused by the rotation of the blades. The transformations between the blade coordinate systems and the tower coordinate system will depend on the instantaneous azimuth positions of the blades as they rotate. Frequency domain analysis are much faster than time simulations and in some respects they give more insight into the dynamics of the structure. However, the non-linear terms in the dynamic equations for a complex wind turbine structure are usually thought to preclude the use of frequency domain methods. Design Basis 2 is used to verify the frequency domain model comparing loads on the structure calculated with the frequency domain model both to loads calculated with the time domain model and to measured loads. Examples show that frequency and time domain calculations of typical PSD`s of loads are in very good agreement. Also the agreement between the calculated and measured PSD`s is good. Moreover, Design Basis 2 has shown that the frequency domain model results in an extremely fast calculation method.

  8. Heliolatitude structure of the solar wind proton speed and density at 1 AU for heliospheric modeling

    NASA Astrophysics Data System (ADS)

    Sokol, Justyna Maria; Swaczyna, Pawel; Bzowski, Maciej; Tokumaru, Munetoshi

    2014-05-01

    The heliolatitudinal structure of solar wind proton speed and density varies with solar activity. A model of its variation with time is needed for heliospheric studies and modeling. It is important for the global heliospheric structure, allows for an assessment of ionization rates of neutral species in the heliosphere and interpretation of observations of the energetic neutral atoms and neutral interstellar atoms. Sokół et al. 2013 presented a model of the heliolatitudinal and time variations of solar wind structure based on results of the computer assisted tomography analysis of the solar wind speed enabled by remote-sensing observations of interplanetary scintillations, in-situ measurements from Ulysses, and in-ecliptic measurements from various missions gathered in the OMNI2 database. They determined the 3D structure of solar wind on a yearly time grid from 1990 to 2011. Now we increase the time resolution of the grid used in the model. Because of the weather conditions in Japan, where the interplanetary scintillation observations are carried out, the solar wind data sets contain systematic gaps. For the purposes of the increase of the time resolution of the model for heliospheric studies the method of filling of these gap is needed. We present a comparison of various methods of gap filling. We present results of the investigation of the procedures of reconstruction of the solar wind density with the use of the solar wind invariants published in the literature. Additionally we study various algorithms of extrapolation of the heliolatitudinal time series of the solar wind proton speed and number density in time.

  9. PULSAR WIND NEBULAE WITH THICK TOROIDAL STRUCTURE

    SciTech Connect

    Chevalier, Roger A.; Reynolds, Stephen P. E-mail: reynolds@ncsu.edu

    2011-10-10

    We investigate a class of pulsar wind nebulae that show synchrotron emission from a thick toroidal structure. The best studied such object is the small radio and X-ray nebula around the Vela pulsar, which can be interpreted as the result of interaction of a mildly supersonic inward flow with the recent pulsar wind. Such a flow near the center of a supernova remnant can be produced in a transient phase when the reverse shock reaches the center of the remnant. Other nebulae with a thick toroidal structure are G106.6+2.9 and G76.9+1.0. Their structure contrasts with young pulsar nebulae like the Crab Nebula and 3C 38, which show a more chaotic, filamentary structure in the synchrotron emission. In both situations, a torus-jet structure is present where the pulsar wind passes through a termination shock, indicating the flow is initially toroidal. We suggest that the difference is due to the Rayleigh-Taylor instability that operates when the outer boundary of the nebula is accelerating into freely expanding supernova ejecta. The instability gives rise to mixing in the Crab and related objects, but is not present in the nebulae with thick toroidal regions.

  10. Structural health monitoring of wind turbines

    SciTech Connect

    Simmermacher, T.; James, G.H. III.; Hurtado, J.E.

    1997-09-01

    To properly determine what is needed in a structural health monitoring system, actual operational structures need to be studied. We have found that to effectively monitor the structural condition of an operational structure four areas must be addressed: determination of damage-sensitive parameters, test planning, information condensation, and damage identification techniques. In this work, each of the four areas has been exercised on an operational structure. The structures studied were all be wind turbines of various designs. The experiments are described and lessons learned will be presented. The results of these studies include a broadening of experience in the problems of monitoring actual structures as well as developing a process for implementing such monitoring systems.

  11. Structural Dynamic Behavior of Wind Turbines

    NASA Technical Reports Server (NTRS)

    Thresher, Robert W.; Mirandy, Louis P.; Carne, Thomas G.; Lobitz, Donald W.; James, George H. III

    2009-01-01

    The structural dynamicist s areas of responsibility require interaction with most other members of the wind turbine project team. These responsibilities are to predict structural loads and deflections that will occur over the lifetime of the machine, ensure favorable dynamic responses through appropriate design and operational procedures, evaluate potential design improvements for their impact on dynamic loads and stability, and correlate load and control test data with design predictions. Load prediction has been a major concern in wind turbine designs to date, and it is perhaps the single most important task faced by the structural dynamics engineer. However, even if we were able to predict all loads perfectly, this in itself would not lead to an economic system. Reduction of dynamic loads, not merely a "design to loads" policy, is required to achieve a cost-effective design. The two processes of load prediction and structural design are highly interactive: loads and deflections must be known before designers and stress analysts can perform structural sizing, which in turn influences the loads through changes in stiffness and mass. Structural design identifies "hot spots" (local areas of high stress) that would benefit most from dynamic load alleviation. Convergence of this cycle leads to a turbine structure that is neither under-designed (which may result in structural failure), nor over-designed (which will lead to excessive weight and cost).

  12. The neutral wind in ionospheric modeling: the month-long ISR campaign at Millstone Hill, October 2002

    NASA Astrophysics Data System (ADS)

    David, M.; Sojka, J. J.; Schunk, R. W.; Holt, J. M.

    2013-12-01

    The thermospheric wind is one of the most important inputs in modeling the mid-latitude ionosphere; unfortunately the currently available models do not seem to provide a very accurate representation of it. When running an ionospheric model, such as Utah State University's TDIM, the neutral wind input has a large effect on both the peak density of the F-layer (NmF2) as well as the height of the layer (hmF2). The month-long campaign of the Incoherent Scatter Radar at Millstone Hill provides an excellent base for the comparison of model runs to observations, to determine what sort of neutral wind is needed to provide a match with the height and peak density of the F layer. The data base shows a marked degree of day-to-day variability in two regards: the value of NmF2 (or TEC) at the time of sunrise (approximately 1100 hrs UT), and the rate at which the value of TEC increases during the morning sunlit hours. In a previous study we showed that this day-to-day variability could be accounted for by variations in either a neutral wind, or a penetrating electric field. Recent work has indicated that in this case the electric field will not account for the variation, therefore we look to the neutral wind. Total Electron Content (TEC) at Millstone Hill during the month-long ISR campaign of October 2002. Notice the day-to-day variability in the TEC value at the time of sunrise (about 1100 UT) as well as the rate at which TEC increases during the morning hours.

  13. Spectrum Analysis of the Wind Farm Power based on the Spatial Structures of Wind

    NASA Astrophysics Data System (ADS)

    Kawamoto, Teru; Yamashita, Masaru

    Spectrum analysis has been carried out based on the spatial structure model of wind. Power fluctuation from nine wind turbines arranged in 3 × 3 manner is less than that from a single turbine, regardless of wind direction. The increased distance between two turbines slightly reduces power fluctuation. In case of an inline arrangement, power fluctuation caused by the wind perpendicular to the turbine line is lower than that by the wind parallel to the turbine line, because the coherence of wind perpendicular to the wind direction decays sharply. For double line arrangement, fluctuation will be almost the same for the 3 × 3 arrangement.

  14. 26Al Production in the Early Solar Nebula by Neutral High-Energy Plasma Winds

    NASA Astrophysics Data System (ADS)

    Spergel, M. S.

    1995-09-01

    In the light of recent observations, I believe that the sources for the presence of ^26Al within the solar nebula must be reconsidered [2,3]. Recent low observational estimates of the probability of encounters between mass-losing evolved stars and molecular clouds [4] for the production of ^26Al and the observed low production [5] of 26 Al from AGB (Asymptotic Giant Branch stars) along with the predicted low abundance of cosmic ray induced local production [6] in the early solar nebula all support continued investigation for additional sources of the solar nebula ^26Al presence. It is suggested based on the presences of new cross section data [7], that an important source of this ^26Al presence might be from enhanced interactions from the collisions of the local "T. Tauri" like plasma winds with the atomic and molecular Early Solar Nebula (ESN). Interactions like ^26Mg (p,n) ^26Al in this "neutral" electrical setting may provide the needed selective production. The ESN provides an environment where plasma winds can lead to such nucleosynthesis. Stellar winds of 300-700 km/s (about 3x10^7 K) are seen to T. Tauri like stars, presumed precursor to solar like stars, and also within the Solar heliosphere [8.9]. These winds provide the source of Solar High Energy Particles which can interact with such in situ targets such as ^26Mg to produce the ^26Al. The presence of the atomic and molecular environments, will enhance [10] nucleosynthesis over that seen in scattering of protons off bare nuclei. Such enhancement has been recently observed in low energy scattering on electrically shield targets [7]. There it was also suggested that in stellar convective zones, electron clouds of the plasma shield may also shield bare target nuclei. Measured values of low energy proton scattered on atomic and molecular targets indicated [7] that fusion cross sections are enlarged and elastic cross sections are reduced, therefore simple extrapolation of accelerator data can lead to an

  15. Using IBEX data to constrain the heliosphere's large-scale structure: interstellar neutral gas and the Warm Breeze

    NASA Astrophysics Data System (ADS)

    Bzowski, Maciej; McComas, David; Galli, Andre; Kucharek, Harald; Wurz, Peter; Sokol, Justyna M.; Schwadron, Nathan; Heirtzler, David M.; Kubiak, M. Marzena A.; Möbius, Eberhard; Fuselier, Stephen; Swaczyna, Paweł; Leonard, Trevor; Park, Jeewoo

    2016-07-01

    The large-scale structure of the heliosphere is governed by the interaction of the partly ionized, magnetized interstellar gas and the magnetized, fully ionized solar wind, structured in heliolatitude. Determining factors of this interaction are the density and flow velocity of interstellar gas relative to the Sun, the Mach number of this flow and the strength and inclination of the interstellar magnetic field to the flow vector at the interstellar side, and the magnitude of dynamic pressure of solar wind and the strength of its embedded magnetic field at the solar side. As a result of charge exchange interactions operating in the boundary region between the heliosphere and interstellar matter, a new population of neutral atoms is created, in addition to the population of unperturbed interstellar neutral gas. Both of these populations penetrate deep inside the heliosphere, where they can be sampled by the first space probe dedicated to observations of the heliosphere and its immediate surroundings by means of neutral atoms: the Interstellar Boundary Explorer (IBEX). Due to distortion of the heliosphere from axial symmetry, the secondary population of interstellar neutrals, created via charge exchange between the plasma flowing past the heliopause and the unperturbed pristine neutral interstellar gas, appears to be coming from a different direction than the unperturbed interstellar neutral flow. These two directions should be coplanar with the plane defined by the local interstellar magnetic field and the flow direction of the unperturbed gas. IBEX provides an unprecedented opportunity to study and interpret these relations. The IBEX science team have recently accomplished important milestones in researching the primary and secondary populations of interstellar gas and their relation to the local interstellar magnetic fields. First, the temperature and velocity vector of the inflowing interstellar neutral gas has been determined with unprecedented robustness based

  16. Comparison of a simple logarithmic and equivalent neutral wind approaches for converting buoy-measured wind speed to the standard height: special emphasis to North Indian Ocean

    NASA Astrophysics Data System (ADS)

    Singh, Prem; Parekh, Anant; Attada, Raju

    2013-02-01

    The difference between the transferred wind speed to 10-m height based on the equivalent neutral wind approach ( U n) and the logarithmic approach ( U log) is studied using in situ observations from the Indian, Pacific, and Atlantic Oceans, with special emphasis given to the North Indian Ocean. The study included U n - U log variations with pressure, relative humidity, wind speed, air temperature, and sea surface temperature (SST). U n - U log variation with respect to air temperature ( T a) reveals that U n - U log is out of phase with air temperature. Further analysis found that U n - U log is in phase with SST ( T s) - T a and varies between -1.0 and 1.0 m/s over the North Indian Ocean, while for the rest of the Oceans, it is between -0.3 and 0.8 m/s. This higher magnitude of U n - U log over the North Indian Ocean is due to the higher range of T s - T a (-4 to 6 °C) in the North Indian Ocean. Associated physical processes suggested that the roughness length and friction velocity dependence on the air-sea temperature difference contributes to the U n - U log difference. The study is further extended to evaluate the behavior of U n - U log under cyclonic conditions (winds between 15 and 30 m/s), and it was found that the magnitude of Un - U log varies 0.5-1.5 m/s under the cyclonic wind conditions. The increasing difference with the wind speed is due to the increase in the momentum transfer coefficient with wind speed, which modifies the friction velocity significantly, resulting in U n higher than U log. Thus, under higher wind conditions, U n - U log can contribute up to half the retrieval error (5 % of the wind speed magnitude) to the satellite validation exercise.

  17. Simulation and Analysis of Wind Turbine Loads for Neutrally Stable Inflow Turbulence

    NASA Astrophysics Data System (ADS)

    Sim, C.; Manuel, L.; Basu, S.

    2009-12-01

    Efficient temporal resolution and spatial grids are important in simulation of the inflow turbulence for wind turbine loads analyses. There have not been many published studies that address optimal space-time resolution of generated inflow velocity fields in order to estimate accurate load statistics. This study investigates turbine extreme and fatigue load statistics for a utility-scale 5MW wind turbine with a hub-height of 90 m and a rotor diameter of 126 m. Load statistics, spectra, and time-frequency analysis representations are compared for various alternative space and time resolutions employed in inflow turbulence field simulation. Conclusions are drawn regarding adequate resolution in space of the inflow turbulence simulated on the rotor plane prior to extracting turbine load statistics. Similarly, conclusions are drawn with regard to what constitutes adequate temporal filtering to preserve turbine load statistics. This first study employs conventional Fourier-based spectral methods for stochastic simulation of velocity fields for a neutral atmospheric boundary layer. In the second part of this study, large-eddy simulation (LES) is employed with similar spatial and temporal resolution as in the earlier Fourier-based simulations to again establish turbine load statistics. A comparison of extreme and fatigue load statistics is presented for the two approaches used for inflow field generation. The use of LES-generated flows (enhanced in deficient high-frequency energy by the use of fractal interpolation) to establish turbine load statistics in this manner is computationally very expensive but the study is justified in order to evaluate the ability of LES to be used as an alternative to more common approaches. LES with fractal interpolation is shown to lead to accurate load statistics when compared with stochastic simulation. A more compelling reason for using LES in turbine load studies is the following: for stable boundary layers, it is not possible to

  18. Large eddy simulation of a large wind-turbine array in a conventionally neutral atmospheric boundary layer

    NASA Astrophysics Data System (ADS)

    Allaerts, Dries; Meyers, Johan

    2015-06-01

    Under conventionally neutral conditions, the boundary layer is frequently capped by an inversion layer, which counteracts vertical entrainment of kinetic energy. Very large wind farms are known to depend on vertical entrainment to transport energy from above the farm towards the turbines. In this study, large eddy simulations of an infinite wind-turbine array in a conventionally neutral atmospheric boundary layer are performed. By carefully selecting the initial potential-temperature profile, the influence of the height and the strength of a capping inversion on the power output of a wind farm is investigated. Results indicate that both the height and the strength have a significant effect on the boundary layer flow, and that the height of the neutral boundary layer is effectively controlled by the capping inversion. In addition, it is shown that the vertical entrainment rate decreases for increasing inversion strength or height. In our infinite wind-farm simulations, varying the inversion characteristics leads to differences in power extraction on the order of 13% ± 0.2% (for increasing the strength from 2.5 to 10 K), and 31% ± 0.4% (for increasing the height from 500 to 1500 m). A detailed analysis of the mean kinetic-energy equation is included, showing that the variation in power extraction originates from the work done by the driving pressure gradient related to the boundary layer height and the geostrophic angle, while entrainment of kinetic energy from the free atmosphere does not play a significant role. Also, the effect of inversion strength on power extraction is energetically not related to different amounts of energy entrained, but explained by a difference in boundary layer growth, leading to higher boundary layers for lower inversion strengths. We further present a simple analytical model that allows to obtain wind-farm power output and driving power for the fully developed regime as function of Rossby number and boundary layer height.

  19. Structural health monitoring of wind turbine blades

    NASA Astrophysics Data System (ADS)

    Rumsey, Mark A.; Paquette, Joshua A.

    2008-03-01

    As electric utility wind turbines increase in size, and correspondingly, increase in initial capital investment cost, there is an increasing need to monitor the health of the structure. Acquiring an early indication of structural or mechanical problems allows operators to better plan for maintenance, possibly operate the machine in a de-rated condition rather than taking the unit off-line, or in the case of an emergency, shut the machine down to avoid further damage. This paper describes several promising structural health monitoring (SHM) techniques that were recently exercised during a fatigue test of a 9 meter glass-epoxy and carbon-epoxy wind turbine blade. The SHM systems were implemented by teams from NASA Kennedy Space Center, Purdue University and Virginia Tech. A commercial off-the-shelf acoustic emission (AE) NDT system gathered blade AE data throughout the test. At a fatigue load cycle rate around 1.2 Hertz, and after more than 4,000,000 fatigue cycles, the blade was diagnostically and visibly failing at the out-board blade spar-cap termination point at 4.5 meters. For safety reasons, the test was stopped just before the blade completely failed. This paper provides an overview of the SHM and NDT system setups and some current test results.

  20. Coherent structures in the Es layer and neutral middle atmosphere

    NASA Astrophysics Data System (ADS)

    Mošna, Zbyšek; Knížová, Petra Koucká; Potužníková, Kateřina

    2015-12-01

    The present paper shows results from the summer campaign performed during geomagnetically quiet period from June 1 to August 31, 2009. Within time-series of stratospheric and mesospheric temperatures at pressure levels 10-0.1 hPa, mesospheric winds measured in Collm, Germany, and the sporadic E-layer parameters foEs and hEs measured at the Pruhonice station we detected specific coherent wave-bursts in planetary wave domain. Permanent wave-like activity is observed in all analyzed data sets. However, the number of wave-like structures persistent in large range of height from the stratosphere to lower ionosphere is limited. The only coherent modes that are detected on consequent levels of the atmosphere are those corresponding to eigenmodes of planetary waves.

  1. The interaction between an impact-produced neutral gas cloud and the solar wind at the lunar surface

    NASA Technical Reports Server (NTRS)

    Lindeman, R. A.; Vondrak, R. R.; Freeman, J. W.; Snyder, C. W.

    1974-01-01

    On Apr. 15, 1970, the Apollo 13 S-IVB stage impacted the nighttime lunar surface. Beginning 20 sec after impact, the Suprathermal Ion Detector Experiment and the Solar Wind Spectrometer observed a large flux of positive ions (maximum flux of about 3 x 10 to the 8th ions/sq cm/sec/ster) and electrons. Two separate streams of ions were observed: a horizontal flux that appeared to be deflected solar wind ions and a smaller vertical flux of predominantly heavy ions (greater than 10 amu), which probably were material vaporized from the S-IVB stage. An examination of the data shows that collisions between neutral molecules and hot electrons (50 eV) were probably an important ionization mechanism in the impact-produced neutral gas cloud. These electrons, which were detected by the Solar Wind Spectrometer, are thought to have been energized in a shock front or some form of intense interaction region between the cloud and the solar wind. Thus strong ionization and acceleration are seen under conditions approaching a collisionless state.

  2. Determining the power-law wind-profile exponent under near-neutral stability conditions at sea

    NASA Technical Reports Server (NTRS)

    Hsu, S. A.; Meindl, Eric A.; Gilhousen, David B.

    1994-01-01

    On the basis of 30 samples from near-simultaneous overwater measurements by pairs of anemometers located at different heights in the Gulf of Mexico and off the Chesapeake Bay, Virginia, the mean and standard deviation for the exponent of the power-law wind profile over the ocean under near-neutral atmospheric stability conditions were determined to be 0.11 +/- 0.03. Because this mean value is obtained from both deep and shallow water environments, it is recommended for use at sea to adjust the wind speed measurements at different heights to the standard height of 10 m above the mean sea surface. An example to apply this P value to estimate the momentum flux or wind stress is provided.

  3. Neutral Buoyancy Simulator-NB32-Large Space Structure Assembly

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Once the United States' space program had progressed from Earth's orbit into outerspace, the prospect of building and maintaining a permanent presence in space was realized. To accomplish this feat, NASA launched a temporary workstation, Skylab, to discover the effects of low gravity and weightlessness on the human body, and also to develop tools and equipment that would be needed in the future to build and maintain a more permanent space station. The structures, techniques, and work schedules had to be carefully designed to fit this unique construction site. The components had to be lightweight for transport into orbit, yet durable. The station also had to be made with removable parts for easy servicing and repairs by astronauts. All of the tools necessary for service and repairs had to be designed for easy manipulation by a suited astronaut. Construction methods had to be efficient due to the limited time the astronauts could remain outside their controlled environment. In lieu of all the specific needs for this project, an environment on Earth had to be developed that could simulate a low gravity atmosphere. A Neutral Buoyancy Simulator (NBS) was constructed by NASA Marshall Space Flight Center (MSFC) in 1968. Since then, NASA scientists have used this facility to understand how humans work best in low gravity and also provide information about the different kinds of structures that can be built. As part of this experimentation, the Experimental Assembly of Structures in Extravehicular Activity (EASE) project was developed as a joint effort between MFSC and the Massachusetts Institute of Technology (MIT). The EASE experiment required that crew members assemble small components to form larger components, working from the payload bay of the space shuttle. Pictured is an entire unit that has been constructed and is sitting in the bottom of a mock-up shuttle cargo bay pallet.

  4. Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.

    PubMed

    Rudolph, Michael J; Vance, David J; Cassidy, Michael S; Rong, Yinghui; Shoemaker, Charles B; Mantis, Nicholas J

    2016-08-01

    In this report, we describe the X-ray crystal structures of two single domain camelid antibodies (VH H), F5 and F8, each in complex with ricin toxin's enzymatic subunit (RTA). F5 has potent toxin-neutralizing activity, while F8 has weak neutralizing activity. F5 buried a total of 1760 Å(2) in complex with RTA and made contact with three prominent secondary structural elements: α-helix B (Residues 98-106), β-strand h (Residues 113-117), and the C-terminus of α-helix D (Residues 154-156). F8 buried 1103 Å(2) in complex with RTA that was centered primarily on β-strand h. As such, the structural epitope of F8 is essentially nested within that of F5. All three of the F5 complementarity determining regions CDRs were involved in RTA contact, whereas F8 interactions were almost entirely mediated by CDR3, which essentially formed a seventh β-strand within RTA's centrally located β-sheet. A comparison of the two structures reported here to several previously reported (RTA-VH H) structures identifies putative contact sites on RTA, particularly α-helix B, associated with potent toxin-neutralizing activity. This information has implications for rational design of RTA-based subunit vaccines for biodefense. Proteins 2016; 84:1162-1172. © 2016 Wiley Periodicals, Inc. PMID:27159829

  5. Structure of wind-shear turbulence

    NASA Technical Reports Server (NTRS)

    Trevino, G.; Laituri, T. R.

    1988-01-01

    The statistical characteristics of wind-shear turbulence are modelled. Isotropic turbulence serves as the basis of comparison for the anisotropic turbulence which exists in wind shear. The question of how turbulence scales in a wind shear is addressed from the perspective of power spectral density.

  6. Structure of wind-shear turbulence

    NASA Technical Reports Server (NTRS)

    Trevino, G.; Laituri, T. R.

    1989-01-01

    The statistical characteristics of wind shear turbulence are modelled. Isotropic turbulence serves as the basis of comparison for the anisotropic turbulence which exists in wind shear. The question of turbulence scales in wind shear is addressed from the perspective of power spectral density.

  7. Asymptotic structure of hydromagnetically driven relativistic winds

    NASA Technical Reports Server (NTRS)

    Chiueh, Tzihong; Li, Zhi-Yun; Begelman, Mitchell C.

    1991-01-01

    A fully relativistic analysis has been performed of the asymptotic structure of stationary axisymmetric hydromagnetic winds. If a flow fills the region containing the rotation axis, then the flux surfaces in the flow must collimate to a set of current-carrying cylindrical surface extending to infinite transverse radius, collimate to a set of cylindrical surfaces extending to a finite radius, or collimate to a current-free paraboloidal field configuration which fills up the entire space. If an asymptotically cylindrical flow carries a finite current at radii well beyond the light cylinder, then the Lorentz factor of the terminal flow speed on a given flux surface is proportional to the total current enclosed within this flux surface. If a flow is of type II paraboloidal, then its asymptotic energy flux is carried entirely by the gas motion rather than the electromagnetic fields.

  8. Turbulent kinetics of a large wind farm and their impact in the neutral boundary layer

    DOE PAGESBeta

    Na, Ji Sung; Koo, Eunmo; Munoz-Esparza, Domingo; Jin, Emilia Kyung; Linn, Rodman; Lee, Joon Sang

    2015-12-28

    High-resolution large-eddy simulation of the flow over a large wind farm (64 wind turbines) is performed using the HIGRAD/FIRETEC-WindBlade model, which is a high-performance computing wind turbine–atmosphere interaction model that uses the Lagrangian actuator line method to represent rotating turbine blades. These high-resolution large-eddy simulation results are used to parameterize the thrust and power coefficients that contain information about turbine interference effects within the wind farm. Those coefficients are then incorporated into the WRF (Weather Research and Forecasting) model in order to evaluate interference effects in larger-scale models. In the high-resolution WindBlade wind farm simulation, insufficient distance between turbines createsmore » the interference between turbines, including significant vertical variations in momentum and turbulent intensity. The characteristics of the wake are further investigated by analyzing the distribution of the vorticity and turbulent intensity. Quadrant analysis in the turbine and post-turbine areas reveals that the ejection motion induced by the presence of the wind turbines is dominant compared to that in the other quadrants, indicating that the sweep motion is increased at the location where strong wake recovery occurs. Regional-scale WRF simulations reveal that although the turbulent mixing induced by the wind farm is partly diffused to the upper region, there is no significant change in the boundary layer depth. The velocity deficit does not appear to be very sensitive to the local distribution of turbine coefficients. However, differences of about 5% on parameterized turbulent kinetic energy were found depending on the turbine coefficient distribution. Furthermore, turbine coefficients that consider interference in the wind farm should be used in wind farm parameterization for larger-scale models to better describe sub-grid scale turbulent processes.« less

  9. Turbulent kinetics of a large wind farm and their impact in the neutral boundary layer

    SciTech Connect

    Na, Ji Sung; Koo, Eunmo; Munoz-Esparza, Domingo; Jin, Emilia Kyung; Linn, Rodman; Lee, Joon Sang

    2015-12-28

    High-resolution large-eddy simulation of the flow over a large wind farm (64 wind turbines) is performed using the HIGRAD/FIRETEC-WindBlade model, which is a high-performance computing wind turbine–atmosphere interaction model that uses the Lagrangian actuator line method to represent rotating turbine blades. These high-resolution large-eddy simulation results are used to parameterize the thrust and power coefficients that contain information about turbine interference effects within the wind farm. Those coefficients are then incorporated into the WRF (Weather Research and Forecasting) model in order to evaluate interference effects in larger-scale models. In the high-resolution WindBlade wind farm simulation, insufficient distance between turbines creates the interference between turbines, including significant vertical variations in momentum and turbulent intensity. The characteristics of the wake are further investigated by analyzing the distribution of the vorticity and turbulent intensity. Quadrant analysis in the turbine and post-turbine areas reveals that the ejection motion induced by the presence of the wind turbines is dominant compared to that in the other quadrants, indicating that the sweep motion is increased at the location where strong wake recovery occurs. Regional-scale WRF simulations reveal that although the turbulent mixing induced by the wind farm is partly diffused to the upper region, there is no significant change in the boundary layer depth. The velocity deficit does not appear to be very sensitive to the local distribution of turbine coefficients. However, differences of about 5% on parameterized turbulent kinetic energy were found depending on the turbine coefficient distribution. Furthermore, turbine coefficients that consider interference in the wind farm should be used in wind farm parameterization for larger-scale models to better describe sub-grid scale turbulent processes.

  10. IUE's View of Callisto: Detection of an SO2 Absorption Correlated to Possible Torus Neutral Wind Alterations

    NASA Technical Reports Server (NTRS)

    Lane, Arthur L.; Domingue, Deborah L.

    1997-01-01

    Observations taken with the International Ultraviolet Explorer (IUE) detected a 0.28 micron absorption feature on Callisto's leading and Jupiter-facing hemispheres. This feature is similar to Europa's 0.28 micron feature, however it shows no correlation with magnetospheric ion bombardment. The strongest 0.28 micron signature is seen in the region containing the Valhalla impact. This absorption feature also shows some spatial correlation to possible neutral wind interactions, suggestive of S implantation (rather than S(sub x)) into Callisto's water ice surface, Indications of possible temporal variations (on the 10% level) are seen at other wavelengths between the 1984-1986 and the 1996 observations.

  11. Measurement of Neutral Winds and Gradients in the Lower Thermosphere with Multi-Point, Chemical-Release Sounding Rocket Payloads.

    NASA Astrophysics Data System (ADS)

    Andersen, C.

    2014-12-01

    Sounding rocket payloads capable of deploying multi-point chemical releases provide a unique tool for investigating the properties of the lower thermosphere. This type of payload consists of a collection of sub-payloads that are propelled laterally out of the rocket during flight. Each contains a canister of liquid tracer (such as tri-methyl aluminum) which, after separating from the main rocket, is dispersed by explosive detonation. The result is a luminous "puff" that can be tracked by triangulation using images taken from several ground stations, producing wind vector velocities with typical uncertainties of just 1-2 m/s. A deployment of puffs throughout a 3-dimensional volume spanning approximately 100x100 km horizontally and from 100 to 180 km altitude, vertically, makes it possible to measure the height profiles of all nine first-order spatial gradients of the neutral wind vector in the lower thermosphere.

  12. Observations of Density and Electron neutral collision frequency in the nighttime E-region during the E-winds Campaign

    NASA Astrophysics Data System (ADS)

    Swenson, C.; Ward, J.; Carlson, C.; Earle, G.

    2004-12-01

    Four Utah State University Plasma Impedance Probes (PIP) were part of NASA's Sequential Rocket Study of Descending Layers in the E-Region (E-Winds). The payloads were launched at 11:19 pm, 1:41 am, 2:50 am and 3:07 am on June 30 and July 1, 2003 from Wallops Island, Virginia into the nighttime D and E-regions. These instruments provided observations of electron density and electron collision frequencies along the trajectory of the rockets. The neutral winds were measured with simultaneous TMA releases. The rockets flew into nighttime intermediate layers located between 100 to 225 km in altitude. The analysis of flight data shows a considerable amount of variability in these layers over a relativity small temporal and spatial scales. This paper presents a overview of these multi-point measurements of the mid latitude ionosphere in the context of the geomagnetic activity during the flights.

  13. Effects of the geomagnetic asymmetry of flux-tube integrated neutral winds to the Rayleigh-Taylor instability in equatorial ionosphere

    NASA Astrophysics Data System (ADS)

    Luo, Weihua; Xu, Jisheng; Tian, Mao

    Neutral winds play an important role in the develop-ment of Rayleigh-Taylor instability which is very associated with the occurrence of irregularities in the equatorial and low-latitude regions. For example, eastward winds would make for the development of R-T instability and meridional winds suppress the development of R-T insta-bility. In this work, we investigate effects of the geomagnetic asymmetry of neutral winds to the flux-tube integrated R-T instability in equatorial ionosphere. The flux-tube integrated lin-ear growth rate of R-T instability were estimated and considering the ambient electric fields and asymmetry of neutral winds between North-South hemispheres, and the integrated growth rates were compared which were get with and without the neutral wind, including the zonal and meridional wind. Effects of the longitudinal distribution of the meridional winds on the inte-grated growth rate are investigated also. It is shown that the zonal and meridional wind could significantly affect the growth rates and the meridional winds could decrease the integrated growth rate, respectively. The longitudinal variation of occurrence of irregularities would be related with the global distribution of meridional wind. Reference: Sultan, P.J., Linear theory and modeling of the Rayleigh-Taylor instability leading to the occurrence of equatorial spread F, J. Geophys. Res., 1996, 101(A12), 26875-26891 Basu, B., On the linear theory of equato-rial plasma instability: Comparison of different descriptions, J. Geophys. Res., 2002, 107(A8), 1199, doi: 10.1029/2001JA000317

  14. Dynamic Wind Loads and Vortex Structures in the Wake of a Wind Turbine

    NASA Astrophysics Data System (ADS)

    Hu, Hui; Yang, Zifeng; Sarkar, Partha

    2010-11-01

    We report an experimental study to characterize the dynamic wind loads and evolution of wake vortex flow structures downstream of a horizontal axis wind turbine (HAWT). The experiments were conducted in a wind tunnel with a wind turbine model placed in a boundary layer flow developed over rough and smooth surfaces in order to study the effects of roughness and the resulting velocity and turbulence fields on the wake characteristics and fatigue loads acting on the wind turbine. In addition to measuring dynamic wind loads (both aerodynamic forces and moments) acting on the wind turbine model using a six-component load cell, a high-resolution Particle Image Velocimetry (PIV) system was used to make phase-locked flow field measurements to quantify the time-evolution of the wake vortex and turbulence flow structures shedding from wind turbine blades. The detailed flow field measurements were correlated with the wind load measurements to elucidate the underlying physics associated with turbine power generation and fatigue loads acting on wind turbines.

  15. Correcting the Record on the Analysis of IBEX and STEREO Data Regarding Variations in the Neutral Interstellar Wind

    NASA Astrophysics Data System (ADS)

    Frisch, P. C.; Bzowski, M.; Drews, C.; Leonard, T.; Livadiotis, G.; McComas, D. J.; Möbius, E.; Schwadron, N.; Sokół, J. M.

    2015-03-01

    The journey of the Sun through space carries the solar system through a dynamic interstellar environment that is presently characterized by a Mach ~1 motion between the heliosphere and the surrounding warm partially ionized interstellar cloud. The interaction between the heliosphere and interstellar medium is an evolving process due to variable solar wind properties and the turbulent nature of the interstellar cloud that surrounds the heliosphere. Frisch et al. presented a meta-analysis of the historical data on the interstellar wind flowing through the heliosphere and concluded that temporal changes in the ecliptic longitude of the flow direction with time were statistically indicated by the data available in the refereed literature at the time of that writing. Lallement & Bertaux disagree with this result, and suggested, for instance, that a key instrumental response function of IBEX-Lo was incorrect and that the STEREO pickup ion data are unsuitable for diagnosing the flow of interstellar neutrals through the heliosphere. In this paper we first show that temporal variations in the interstellar wind through the heliosphere are consistent with our knowledge of the very local interstellar medium. The statistical analysis of the helium wind data is revisited, and a recent correction of a typographical error in the literature is incorporated into the new fits. With this correction, and including no newer IBEX results, these combined data still indicate that a change in the longitude of the interstellar neutral wind of λ = 5.°6 ± 2.°4 over the past forty years remains statistically likely, but an constant flow longitude is now statistically possible. Other scenarios for the selection of subsets of these data used in the fitting process produce similar conclusions. We show that the speculations made by Lallement & Bertin about the IBEX instrumental response function are incorrect, and that their other objections to the data used in the meta-analysis are either

  16. The High-latitude Electric Potential Disparity and Hemispheric Differences in the Upper Thermospheric Neutral Wind Circulation

    NASA Astrophysics Data System (ADS)

    Foerster, M.; Haaland, S.; Cnossen, I.

    2014-12-01

    We present statistical studies of both the high-latitude ionospheric potential pattern deduced from long-term observations of the Cluster Electron Drift Instrument (EDI) and upper thermospheric neutral wind circulation patterns in the Northern (NH) and Southern Hemisphere (SH) obtained from accelerometers on board of low-Earth orbiting satellites like CHAMP during about the same time interval. The cross-polar cap potential difference during southward IMF conditions appears to be on average slightly (~7%) larger in the SH compared with the NH, while the neutral wind magnitude and vorticity amplitude are mostly larger in the NH than in the SH, especially during high solar activity conditions. We attribute such behaviour to peculiarities of the hemispheres due to the non-dipolar portions of Earth's main magnetic field that constitute substantial differences between the geomagnetic field configurations of both hemispheres. They cause in particular different magnetic field flux densities in the opposite polar regions and different offsets of the invariant poles with respect to the rotation axis of the Earth. The pole is presently displaced almost twice the distance in the SH compared to the NH, which has substantial implications for the coupled magnetosphere-ionosphere-thermosphere system under the influence of external drivers. To analyse this behaviour, we have run several numerical simulations using the first-principle Coupled Magnetosphere-Ionosphere-Thermosphere (CMIT) model under various seasonal conditions. The survey of both the numerical simulation results and the observations confirm prominent asymmetries between the two hemispheres for these parameters.

  17. Foil chaff ejection systems for rocket-borne measurement of neutral winds in the mesosphere and lower thermosphere

    NASA Astrophysics Data System (ADS)

    Koizumi, Yoshiko; Shimoyama, Manabu; Oyama, Koh-Ichiro; Murayama, Yasuhiro; Tsuda, Toshitaka; Nakamura, Takuji

    2004-07-01

    The foil chaff technique has been used on microrockets such as "Viper" for a long time to measure neutral winds with high altitude resolution in the mesosphere and lower thermosphere. We have developed two new foil chaff storage and ejection systems for muti-instrumented sounding rockets. The first system uses a spring loaded split cylinder which holds the foil chaff, housed in an outer cylinder. The shaft of the split cylinder is kept in place by a lock plate and a stainless steel wire. The split cylinder is ejected by cutting the wire. The second system is of differential pressure type. The cap of an airtight cylinder has a shaft and a sponge piece for sweeping out the foil chaff. The cylinder is sealed at ground level and at the desired height of release, the cap comes out due to differential pressure and brings out the foil chaff. Both these systems were successfully tested on a Japanese sounding rocket in January 2000, releasing about 20 000 pieces of foil chaff during the rocket's descent. Neutral winds were measured in the height range of 85.5-95.0 km with a height resolution of 300 m.

  18. Structural Basis of Human Parechovirus Neutralization by Human Monoclonal Antibodies

    PubMed Central

    Shakeel, Shabih; Westerhuis, Brenda M.; Ora, Ari; Koen, Gerrit; Bakker, Arjen Q.; Claassen, Yvonne; Wagner, Koen; Beaumont, Tim; Wolthers, Katja C.

    2015-01-01

    ABSTRACT Since it was first recognized in 2004 that human parechoviruses (HPeV) are a significant cause of central nervous system and neonatal sepsis, their clinical importance, primarily in children, has started to emerge. Intravenous immunoglobulin treatment is the only treatment available in such life-threatening cases and has given moderate success. Direct inhibition of parechovirus infection using monoclonal antibodies is a potential treatment. We have developed two neutralizing monoclonal antibodies against HPeV1 and HPeV2, namely, AM18 and AM28, which also cross-neutralize other viruses. Here, we present the mapping of their epitopes using peptide scanning, surface plasmon resonance, fluorescence-based thermal shift assays, electron cryomicroscopy, and image reconstruction. We determined by peptide scanning and surface plasmon resonance that AM18 recognizes a linear epitope motif including the arginine-glycine-aspartic acid on the C terminus of capsid protein VP1. This epitope is normally used by the virus to attach to host cell surface integrins during entry and is found in 3 other viruses that AM18 neutralizes. Therefore, AM18 is likely to cause virus neutralization by aggregation and by blocking integrin binding to the capsid. Further, we show by electron cryomicroscopy, three-dimensional reconstruction, and pseudoatomic model fitting that ordered RNA interacts with HPeV1 VP1 and VP3. AM28 recognizes quaternary epitopes on the capsid composed of VP0 and VP3 loops from neighboring pentamers, thereby increasing the RNA accessibility temperature for the virus-AM28 complex compared to the virus alone. Thus, inhibition of RNA uncoating probably contributes to neutralization by AM28. IMPORTANCE Human parechoviruses can cause mild infections to severe diseases in young children, such as neonatal sepsis, encephalitis, and cardiomyopathy. Intravenous immunoglobulin treatment is the only treatment available in such life-threatening cases. In order to develop more

  19. Near-wake flow structure downwind of a wind turbine in a turbulent boundary layer

    NASA Astrophysics Data System (ADS)

    Zhang, Wei; Markfort, Corey D.; Porté-Agel, Fernando

    2012-05-01

    Wind turbines operate in the surface layer of the atmospheric boundary layer, where they are subjected to strong wind shear and relatively high turbulence levels. These incoming boundary layer flow characteristics are expected to affect the structure of wind turbine wakes. The near-wake region is characterized by a complex coupled vortex system (including helicoidal tip vortices), unsteadiness and strong turbulence heterogeneity. Limited information about the spatial distribution of turbulence in the near wake, the vortex behavior and their influence on the downwind development of the far wake hinders our capability to predict wind turbine power production and fatigue loads in wind farms. This calls for a better understanding of the spatial distribution of the 3D flow and coherent turbulence structures in the near wake. Systematic wind-tunnel experiments were designed and carried out to characterize the structure of the near-wake flow downwind of a model wind turbine placed in a neutral boundary layer flow. A horizontal-axis, three-blade wind turbine model, with a rotor diameter of 13 cm and the hub height at 10.5 cm, occupied the lowest one-third of the boundary layer. High-resolution particle image velocimetry (PIV) was used to measure velocities in multiple vertical stream-wise planes ( x- z) and vertical span-wise planes ( y- z). In particular, we identified localized regions of strong vorticity and swirling strength, which are the signature of helicoidal tip vortices. These vortices are most pronounced at the top-tip level and persist up to a distance of two to three rotor diameters downwind. The measurements also reveal strong flow rotation and a highly non-axisymmetric distribution of the mean flow and turbulence structure in the near wake. The results provide new insight into the physical mechanisms that govern the development of the near wake of a wind turbine immersed in a neutral boundary layer. They also serve as important data for the development and

  20. Generic properties of combinatory maps: Neutral networks of RNA secondary structures

    SciTech Connect

    Reidys, C. |; Stadler, P.F. |; Schuster, P. ||

    1997-03-01

    Random graph theory is used to model and analyze the relationships between sequences and secondary structures of RNA molecules, which are understood as mappings from sequence space into shape space. These maps are non-invertible since there are always many orders of magnitude more sequences than structures. Sequences folding into identical structures form neutral networks. A neutral network is embedded in the set of sequences that are compatible with the given structure. Networks are modeled as graphs and constructed by random choice of vertices from the space of compatible sequences. The theory characterizes neutral networks by the mean fraction of neutral neighbors ({lambda}). The networks are connected and percolate sequence space if the fraction of neutral nearest neighbors exceeds a threshold value ({lambda} > {lambda}*). Below threshold ({lambda} < {lambda}*), the networks are partitioned into a largest giant component and several smaller components. Structures are classified as common or rare according to the sizes of their pre-images, i.e. according to the fractions of sequences folding into them. The neutral networks of any pair of two different common structures almost touch each other, and, as expressed by the conjecture of shape space covering sequences folding into almost all common structures, can be found in a small ball of an arbitrary location in sequence space. The results from random graph theory are compared to data obtained by folding large samples of RNA sequences. Differences are explained in terms of specific features of RNA molecular structures.

  1. Damage tolerance and structural monitoring for wind turbine blades.

    PubMed

    McGugan, M; Pereira, G; Sørensen, B F; Toftegaard, H; Branner, K

    2015-02-28

    The paper proposes a methodology for reliable design and maintenance of wind turbine rotor blades using a condition monitoring approach and a damage tolerance index coupling the material and structure. By improving the understanding of material properties that control damage propagation it will be possible to combine damage tolerant structural design, monitoring systems, inspection techniques and modelling to manage the life cycle of the structures. This will allow an efficient operation of the wind turbine in terms of load alleviation, limited maintenance and repair leading to a more effective exploitation of offshore wind. PMID:25583858

  2. Damage tolerance and structural monitoring for wind turbine blades

    PubMed Central

    McGugan, M.; Pereira, G.; Sørensen, B. F.; Toftegaard, H.; Branner, K.

    2015-01-01

    The paper proposes a methodology for reliable design and maintenance of wind turbine rotor blades using a condition monitoring approach and a damage tolerance index coupling the material and structure. By improving the understanding of material properties that control damage propagation it will be possible to combine damage tolerant structural design, monitoring systems, inspection techniques and modelling to manage the life cycle of the structures. This will allow an efficient operation of the wind turbine in terms of load alleviation, limited maintenance and repair leading to a more effective exploitation of offshore wind. PMID:25583858

  3. Nonlinear regression method for estimating neutral wind and temperature from Fabry-Perot interferometer data.

    PubMed

    Harding, Brian J; Gehrels, Thomas W; Makela, Jonathan J

    2014-02-01

    The Earth's thermosphere plays a critical role in driving electrodynamic processes in the ionosphere and in transferring solar energy to the atmosphere, yet measurements of thermospheric state parameters, such as wind and temperature, are sparse. One of the most popular techniques for measuring these parameters is to use a Fabry-Perot interferometer to monitor the Doppler width and breadth of naturally occurring airglow emissions in the thermosphere. In this work, we present a technique for estimating upper-atmospheric winds and temperatures from images of Fabry-Perot fringes captured by a CCD detector. We estimate instrument parameters from fringe patterns of a frequency-stabilized laser, and we use these parameters to estimate winds and temperatures from airglow fringe patterns. A unique feature of this technique is the model used for the laser and airglow fringe patterns, which fits all fringes simultaneously and attempts to model the effects of optical defects. This technique yields accurate estimates for winds, temperatures, and the associated uncertainties in these parameters, as we show with a Monte Carlo simulation. PMID:24514183

  4. Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization

    SciTech Connect

    Guan, Jian; Bywaters, Stephanie M.; Brendle, Sarah A.; Lee, Hyunwook; Ashley, Robert E.; Makhov, Alexander M.; Conway, James F.; Christensen, Neil D.; Hafenstein, Susan

    2015-09-15

    Cryo-electron microscopy (cryo-EM) was used to solve the structures of human papillomavirus type 16 (HPV16) complexed with fragments of antibody (Fab) from three different neutralizing monoclonals (mAbs): H16.1A, H16.14J, and H263.A2. The structure-function analysis revealed predominantly monovalent binding of each Fab with capsid interactions that involved multiple loops from symmetry related copies of the major capsid protein. The residues identified in each Fab-virus interface map to a conformational groove on the surface of the capsomer. In addition to the known involvement of the FG and HI loops, the DE loop was also found to constitute the core of each epitope. Surprisingly, the epitope mapping also identified minor contributions by EF and BC loops. Complementary immunological assays included mAb and Fab neutralization. The specific binding characteristics of mAbs correlated with different neutralizing behaviors in pre- and post-attachment neutralization assays. - Highlights: • We present HPV16-Fab complexes from neutralizing mAbs: H16.1A, H16.14J, and H263.A2. • The structure-function analysis revealed predominantly monovalent binding of each mAb. • Capsid–Fab interactions involved multiple loops from symmetry related L1 proteins. • Besides the known FG and HI loops, epitope mapping also identified DE, EF, and BC loops. • Neutralizing assays complement the structures to show multiple neutralization mechanisms.

  5. Structure of Rotavirus Outer-Layer Protein VP7 Bound with a Neutralizing Fab

    SciTech Connect

    Aoki, Scott T.; Settembre, Ethan C.; Trask, Shane D.; Greenberg, Harry B.; Harrison, Stephen C.; Dormitzer, Philip R.

    2009-06-17

    Rotavirus outer-layer protein VP7 is a principal target of protective antibodies. Removal of free calcium ions (Ca{sup 2+}) dissociates VP7 trimers into monomers, releasing VP7 from the virion, and initiates penetration-inducing conformational changes in the other outer-layer protein, VP4. We report the crystal structure at 3.4 angstrom resolution of VP7 bound with the Fab fragment of a neutralizing monoclonal antibody. The Fab binds across the outer surface of the intersubunit contact, which contains two Ca{sup 2+} sites. Mutations that escape neutralization by other antibodies suggest that the same region bears the epitopes of most neutralizing antibodies. The monovalent Fab is sufficient to neutralize infectivity. We propose that neutralizing antibodies against VP7 act by stabilizing the trimer, thereby inhibiting the uncoating trigger for VP4 rearrangement. A disulfide-linked trimer is a potential subunit immunogen.

  6. Dynamics of Low-latitude Thermosphere-Ionosphere from Coincident Observations of Zonal Neutral Winds and EPB Velocity from Brazil and Peru

    NASA Astrophysics Data System (ADS)

    Chapagain, N. P.; Makela, J. J.; Meriwether, J. W.; Fisher, D. J.; Chau, J. L.; Buriti, R.

    2013-05-01

    The Remote Equatorial Nighttime Observatory of Ionospheric Regions (RENOIR) experiment comprises a suite of instruments operating in northeastern Brazil at Cajazeiras (6.86°S, 38.56°W) and Cariri (7.38°S, 36.53°W) since 2009. This experiment consists of a wide-angle imaging system at Cajazeiras and Fabry-Perot interferometers (FPI) at each site. As part of a separate experiment, two FPIs were deployed in western Peru at Merihill (11.96°S, 76.86°W) and Nazca (14.97°S, 74.89°W) in 2010. In this presentation, we discuss the results obtained from these experiments. When operating individually, each FPI provides measurements of the zonal or meridional neutral winds in the cardinal look directions. A second mode is available, the common volume mode, in which two FPIs (in either Brazil or Peru) make coordinated and collocated measurements of both the zonal and meridional winds. Using the resultant data, we present the climatology of thermospheric neutral winds during the transition from the deep solar minimum to the impending solar maximum conditions from both the east and west coasts of South America. Furthermore, we discuss the coupling between the thermosphere and ionosphere through an analysis of coincident observations of the zonal neutral winds and the drift velocities of Equatorial Plasma Bubbles (EPBs). The results show the neutral winds and EPB drift velocities agree well, illustrating that the F-region dynamo is, in general, fully developed. However, in the early evening hours, the EPB drift velocity is slower than that of the neutral winds on several occasions suggesting the F-region dynamo is not fully activated during the development phase of the EPBs.

  7. Simulation of period doubling of recurrent solar wind structures

    NASA Technical Reports Server (NTRS)

    Whang, Y. C.; Burlaga, L. F.

    1990-01-01

    Based on satellite observations of a recurrent solar wind structure conducted in 1974, an MHD simulation model, and input functions generated from plasma and magnetic field data, the continuing evolution of the solar wind structure outside 5 AU is studied. The model uses the Rankine-Hugoniot relations to describe the jumps in flow properties across the shocks, and it treats shocks as surfaces of discontinuity with zero thickness. Two interaction processes (the collision and the merging of shocks) play important roles in restructuring the solar wind in the outer heliosphere. The simulation result shows that period doubling occurs between 5 and 10 AU. The recurrent solar wind appears to be a persistent new structure between 10 and 20 AU, and it consists of one merged interaction region per solar rotation.

  8. The economic benefits of wind turbine structural testing

    SciTech Connect

    Jackson, K.L.

    1995-09-01

    Wind turbine systems are subjected to highly variable loading conditions as a result of the diverse meteorological conditions found in the field. While the wind energy resource available for extraction and the initial cost of the equipment are major factors in the cost of wind generated electricity, the economic value of any wind power station is ultimately related to the structural lifetime of the machinery located at the plant and to the costs associated with operations and maintenance of the facility. Field experience gained during the past decade has shown large variations in structural lifetime and maintenance costs for identical turbine designs located at dissimilar sites, with resulting dramatic differences in the overall cost of energy produced. Structural testing offers a method for reducing the incidence of wind turbine component failures at any given site by providing an accurate loading envelope for use in detailed equipment lifetime calculations. This paper will broadly discuss the technical issues which are important for turbine field testing and will identify the potential impacts on overall wind plant economics. Wind turbine testing plays a key role in reducing the risk of premature component failure, improving overall mechanical reliability, and enhancing turbine availability.

  9. Electrospray neutralization process and apparatus for generation of nano-aerosol and nano-structured materials

    DOEpatents

    Bailey, Charles L.; Morozov, Victor; Vsevolodov, Nikolai N.

    2010-08-17

    The claimed invention describes methods and apparatuses for manufacturing nano-aerosols and nano-structured materials based on the neutralization of charged electrosprayed products with oppositely charged electrosprayed products. Electrosprayed products include molecular ions, nano-clusters and nano-fibers. Nano-aerosols can be generated when neutralization occurs in the gas phase. Neutralization of electrospan nano-fibers with molecular ions and charged nano-clusters may result in the formation of fibrous aerosols or free nano-mats. Nano-mats can also be produced on a suitable substrate, forming efficient nano-filters.

  10. Spiropyran salts and their neutral precursors: synthesis, crystal structure, photochromic transformations in solutions and solid state

    NASA Astrophysics Data System (ADS)

    Yurieva, E. A.; Aldoshin, S. M.

    2015-06-01

    This review covers investigations of spiropyran iodides with N-substituted indoline fragment, and with the pyran cycle being annelated to N-methylated pyridine ring. The schemes of synthesis of iodides and their neutral precursors, as well as results of X-ray analysis and photochemical study of the crystals of the obtained compounds are presented. Based on our and literature data, the relationship between the structure and photochromic properties has been discussed for a series of salts and neutral pyridospiropyrans.

  11. Neutral Buoyancy Simulator - NB32 - Large Space Structure

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The Hubble Space Telescope (HST) is a cooperative program of the European Space Agency (ESA) and the National Aeronautical and Space Administration (NASA) to operate a long-lived space-based observatory; it was the flagship mission of NASA's Great Observatories program. The HST program began as an astronomical dream in the 1940s. During the 1970s and 1980s, HST was finally designed and built; and it finally became operational in the 1990s. HST was deployed into a low-Earth orbit on April 25, 1990 from the cargo bay of the Space Shuttle Discovery (STS-31). The design of the HST took into consideration its length of service and the necessity of repairs and equipment replacement by making the body modular. In doing so, subsequent shuttle missions could recover the HST, replace faulty or obsolete parts and be re-released. MSFC's Neutral Buoyancy Simulator served as the training facility for shuttle astronauts for Hubble related missions. Shown is astronaut Sharnon Lucid having her life support system being checked prior to entering the NBS to begin training on the space telescope axial scientific instrument changeout.

  12. Electronic structure of neutral and singly ionized curium

    SciTech Connect

    Worden, E.F.; Conway, J.G.; Blaise, J.

    1985-02-01

    Extensive observations and analyses of the emission spectra of neutral and singly ionized curium, Cm I and Cm II, have resulted in the determination of 785 Cm I and 598 Cm II energy levels. These levels then combine to classify 9145 of the more than 14,250 lines of /sup 244/Cm observed between 240 and 2650 nm. Most of the levels have Lande g-values from Zeeman effect data and isotope shifts trom measurements of spectra from sources with various enrichments of /sup 244/Cm, /sup 245/Cm, /sup 246/Cm, and /sup 248/Cm. These data allowed many levels to be assigned to specific electronic configurations. The ground configurations of Cm I and Cm II are (Rn) 5f/sup 7/6d7s/sup 2/ and (Rn) 5f/sup 7/7s/sup 2/, respectively. The realtive energies of other electronic configurations of Cm are given and compared with analogous configurations in other actinides and in Gd its lanthanide analogue. 2 refs., 5 figs., 7 tabs.

  13. Structural basis of respiratory syncytial virus neutralization by motavizumab

    SciTech Connect

    McLellan, Jason S.; Chen, Man; Kim, Albert; Yang, Yongping; Graham, Barney S.; Kwong, Peter D.

    2010-04-13

    Motavizumab is {approx}tenfold more potent than its predecessor, palivizumab (Synagis), the FDA-approved monoclonal antibody used to prevent respiratory syncytial virus (RSV) infection. The structure of motavizumab in complex with a 24-residue peptide corresponding to its epitope on the RSV fusion (F) glycoprotein reveals the structural basis for this greater potency. Modeling suggests that motavizumab recognizes a different quaternary configuration of the F glycoprotein than that observed in a homologous structure.

  14. Wind Turbine Blade Design System - Aerodynamic and Structural Analysis

    NASA Astrophysics Data System (ADS)

    Dey, Soumitr

    2011-12-01

    The ever increasing need for energy and the depletion of non-renewable energy resources has led to more advancement in the "Green Energy" field, including wind energy. An improvement in performance of a Wind Turbine will enhance its economic viability, which can be achieved by better aerodynamic designs. In the present study, a design system that has been under development for gas turbine turbomachinery has been modified for designing wind turbine blades. This is a very different approach for wind turbine blade design, but will allow it to benefit from the features inherent in the geometry flexibility and broad design space of the presented system. It starts with key overall design parameters and a low-fidelity model that is used to create the initial geometry parameters. The low-fidelity system includes the axisymmetric solver with loss models, T-Axi (Turbomachinery-AXIsymmetric), MISES blade-to-blade solver and 2D wing analysis code XFLR5. The geometry parameters are used to define sections along the span of the blade and connected to the CAD model of the wind turbine blade through CAPRI (Computational Analysis PRogramming Interface), a CAD neutral API that facilitates the use of parametric geometry definition with CAD. Either the sections or the CAD geometry is then available for CFD and Finite Element Analysis. The GE 1.5sle MW wind turbine and NERL NASA Phase VI wind turbine have been used as test cases. Details of the design system application are described, and the resulting wind turbine geometry and conditions are compared to the published results of the GE and NREL wind turbines. A 2D wing analysis code XFLR5, is used for to compare results from 2D analysis to blade-to-blade analysis and the 3D CFD analysis. This kind of comparison concludes that, from hub to 25% of the span blade to blade effects or the cascade effect has to be considered, from 25% to 75%, the blade acts as a 2d wing and from 75% to the tip 3D and tip effects have to be taken into account

  15. An Empirical Reference Model of the Quiet-Time Thermospheric Neutral Wind

    NASA Astrophysics Data System (ADS)

    Drob, D. P.

    2014-12-01

    The Horizontal Wind Model (HWM) provides a framework for summarizing five decades of satellite, rocket, and ground-based observations. The development of a statistical consensus of these data provided the means to accurately specify the climatological spatiotemporal variability of upper atmospheric winds as function of day-of-year, time-of-day, latitude, longitude, and altitude. HWM includes representations of annual and semi-annual variations of the general circulation patterns and migrating tides via Fourier modulated vector spherical harmonics, B-splines, and 17,4000 optimally estimated coefficients. The approach works well for the thermosphere which is dominated by forced periodic oscillations driven by in-situ solar heating under the influence of the earths rotation, tilt, and orbit around the sun. Where average climatological specification are adequate for basic research and engineering applications HWM provides a readily accessible observationally based alternative to the need to compute them from first principles. Results from the newly updated version of the model (HWM14) are presented. In this update new satellite- and ground-based observations fill data gaps in the prior observational database of the 250 km altitude region. Additional changes where made to the model formulation to rectify problems near the poles. The model parameter estimation procedure was also improved. In the new approach all 17,400 unknown model parameters are simultaneously estimated using error-weighted sequential optimal estimation theory. This mitigates difficulties from local-time aliasing of synoptically sampled single satellite datasets; however the utilization of multiple satellite- and ground-based datasets is essential. Construction of the reference model also provides the opportunity to inter-compare the new measurements. Results are presented highlighting important aspects of; 1) the thermosphere zonal mean general circulation, 2) equatorial local time variations, 3) the

  16. The dynamic and structure wind waves during strong offshore wind from remote sensing data

    NASA Astrophysics Data System (ADS)

    Titov, Victor; Repina, Irina; Artamonov, Arseniy; Luchinin, Alexsander

    2014-05-01

    For the analysis, field measurements of turbulence characteristics in the layer 1 - 21 m above the sea surface and wind waves at the fetch of about 1 km were used under the wind from the shore having mountain terrain. In the case of the offshore breeze air flow is similar to a jet stream of stably stratified cold air over a warm sea with a maximum speed at a height of about 6 m. The resulting estimates of the height of internal boundary layer are of more than an order of magnitude smaller than traditional ones based only on the change in surface roughness between land and sea. The investigations of near surface wind fields features in internal reservoirs and various regions of seas during last years were conducted by optical complex. The structure of near surface wind fields, eddies, wind fronts, katabatic wind flows for ranges from hundreds meters to some tens kilometers were recorded and analyzed. Derived data of optical monitoring of water surface may serve for future investigations of near surface wind features.

  17. Hemispheric asymmetries in high-latitude ionospheric convection and upper atmosphere neutral wind circulation

    NASA Astrophysics Data System (ADS)

    Foerster, M.; Cnossen, I.; Haaland, S.

    2015-12-01

    Recent observations have shown that the ionospheric/thermospheric response to solar wind and IMF dependent processes in the magnetosphere can be very dissimilar in the Northern and Southern polar regions. We present statistical studies of both the high-latitude ionospheric convection and the upper thermospheric circulation patterns obtained over almost a full solar cycle during the first decade of this century by measurements of the electron drift instrument (EDI) on board the Cluster satellites and by the accelerometer on board the CHAMP spacecraft, respectively. The asymmetries are attributed to the non-dipolar portions of the Earth's magnetic field that constitute hemispheric differences in magnetic flux densities, different offsets of the invariant geomagnetic poles, and generally in different field configurations of both hemispheres. Seasonal and solar cycle effects of the asymmetries are considered and first trials to explain the effects by numerical modeling are presented.

  18. Turbulence structures in wind turbine wake: Effects of atmospheric stratification

    NASA Astrophysics Data System (ADS)

    Bhaganagar, Kiran

    2014-11-01

    Turbulence structure in the wake behind full-scale horizontal-axis WT under the influence of realistic atmospheric turbulent flow conditions has been investigated using actuator-line-model based large-eddy-simulations. Wind turbine simulations have revealed that, in addition to wind shear and ABL turbulence, height-varying wind angle and low-level jets are ABL metrics that influence the structure of turbine wake. Turbulent mixing layer forms downstream of the WT, the strength and size of which decreases with increasing stability. Height dependent wind angle and turbulence are the ABL metrics influencing the lateral wake expansion. Further, ABL metrics strongly impact the evolution of tip and root vortices formed behind the rotor. Two factors play an important role in wake meandering: tip vortex merging due to the mutual inductance form of instability and the corresponding instability of the turbulent mixing layer. NSF CBET Energy for Sustainability.

  19. Coherent structure and Intermittent Turbulence in the Solar Wind Plasma

    NASA Astrophysics Data System (ADS)

    Sondhiya, Deepak Kumar; Gwal, Ashok Kumar; Kasde, Satish Kumar

    2016-07-01

    We analyze the coherent structures and intermittent turbulence in the solar wind plasma using measurements from the Wind spacecraft. Previously established novel wavelet and higher order statistics are used in this work. We analyze the wavelet power spectrum of various solar wind plasma parameters. We construct a statistical significance level in the wavelet power spectrum to quantify the interference effects arising from filling missing data in the time series, allowing extraction of significant power from the measured data. We analyze each wavelet power spectra for transient coherency, and global periodicities resulting from the superposition of repeating coherent structures. Furthermore, these coherent structures are preferentially found in plasma unstable to the mirror and firehose instabilities. These results offer a new understanding of various processes in a turbulent regime. Finally, we discuss the implications of our results for current theories of solar wind generation and describe future work for determining the relationship between the coherent structures in our ionic composition data and the structure of the coronal magnetic field. Keywords: Wavelet Power Spectrum, Coherent structure and Solar wind plasma

  20. The structure of the solar wind in the inner heliosphere

    NASA Astrophysics Data System (ADS)

    Lee, Christina On-Yee

    2010-12-01

    This dissertation is devoted to expanding our understanding of the solar wind structure in the inner heliosphere and variations therein with solar activity. Using spacecraft observations and numerical models, the origins of the large-scale structures and long-term trends of the solar wind are explored in order to gain insights on how our Sun determines the space environments of the terrestrial planets. I use long term measurements of the solar wind density, velocity, interplanetary magnetic field, and particles, together with models based on solar magnetic field data, to generate time series of these properties that span one solar rotation (˜27 days). From these time series, I assemble and obtain the synoptic overviews of the solar wind properties. The resulting synoptic overviews show that the solar wind around Mercury, Venus, Earth, and Mars is a complex co-rotating structure with recurring features and occasional transients. During quiet solar conditions, the heliospheric current sheet, which separates the positive interplanetary magnetic field from the negative, usually has a remarkably steady two- or four-sector structure that persists for many solar rotations. Within the sector boundaries are the slow and fast speed solar wind streams that originate from the open coronal magnetic field sources that map to the ecliptic. At the sector boundaries, compressed high-density and the related high-dynamic pressure ridges form where streams from different coronal source regions interact. High fluxes of energetic particles also occur at the boundaries, and are seen most prominently during the quiet solar period. The existence of these recurring features depends on how long-lived are their source regions. In the last decade, 3D numerical solar wind models have become more widely available. They provide important scientific tools for obtaining a more global view of the inner heliosphere and of the relationships between conditions at Mercury, Venus, Earth, and Mars. When

  1. Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

    SciTech Connect

    McLellan, Jason S.; Yang, Yongping; Graham, Barney S.; Kwong, Peter D.

    2011-09-16

    Respiratory syncytial virus (RSV) invades host cells via a type I fusion (F) glycoprotein that undergoes dramatic structural rearrangements during the fusion process. Neutralizing monoclonal antibodies, such as 101F, palivizumab, and motavizumab, target two major antigenic sites on the RSV F glycoprotein. The structures of these sites as peptide complexes with motavizumab and 101F have been previously determined, but a structure for the trimeric RSV F glycoprotein ectodomain has remained elusive. To address this issue, we undertook structural and biophysical studies on stable ectodomain constructs. Here, we present the 2.8-{angstrom} crystal structure of the trimeric RSV F ectodomain in its postfusion conformation. The structure revealed that the 101F and motavizumab epitopes are present in the postfusion state and that their conformations are similar to those observed in the antibody-bound peptide structures. Both antibodies bound the postfusion F glycoprotein with high affinity in surface plasmon resonance experiments. Modeling of the antibodies bound to the F glycoprotein predicts that the 101F epitope is larger than the linear peptide and restricted to a single protomer in the trimer, whereas motavizumab likely contacts residues on two protomers, indicating a quaternary epitope. Mechanistically, these results suggest that 101F and motavizumab can bind to multiple conformations of the fusion glycoprotein and can neutralize late in the entry process. The structural preservation of neutralizing epitopes in the postfusion state suggests that this conformation can elicit neutralizing antibodies and serve as a useful vaccine antigen.

  2. Mirror Mode Structures in the Solar Wind: STEREO Observations

    NASA Astrophysics Data System (ADS)

    Enríquez-Rivera, O.; Blanco-Cano, X.; Russell, C. T.; Jian, L. K.; Luhmann, J. G.

    2010-03-01

    Mirror mode structures occur in the solar wind either as an isolated magnetic field depression or as trains of magnetic holes (or peaks). Some trains have long durations and have been named mirror mode storms [1]. In this work we investigate mirror mode structures at 1 AU using STEREO A and B high resolution data. Magnetic field data were scanned to search for magnetic holes and peaks in a relatively steady ambient solar wind. We found several examples of mirror mode structures present in the ambient solar wind and also associated with SIRs. In order to study mirror mode origin, we present a case study with mirror mode structures present in the leading edge of a SIR during almost 8 hours corresponding to mirror mode storms. We analyze mirror mode shape and duration as well as plasma and magnetic field conditions that occur in the region surrounding mirror mode storms.

  3. Structure and composition of the neutral upper atmosphere of Mars from the MAVEN NGIMS investigation

    NASA Astrophysics Data System (ADS)

    Mahaffy, P. R.; Benna, M.; Elrod, M.; Yelle, R. V.; Bougher, S. W.; Stone, S. W.; Jakosky, B. M.

    2015-11-01

    The Mars Atmosphere and Volatile EvolutioN (MAVEN) Neutral Gas and Ion Mass Spectrometer (NGIMS) provides sensitive detections of neutral gas and ambient ion composition. NGIMS measurements of nine atomic and molecular neutral species, and their variation with altitude, latitude, and solar zenith angle are reported over several months of operation of the MAVEN mission. Sampling NGIMS signals from multiple neutral species every several seconds reveals persistent and unexpectedly large amplitude density structures. The scale height temperatures are mapped over the course of the first few months of the mission from high down to midlatitudes. NGIMS measurements near the homopause of 40Ar/N2 ratios agree with those reported by the Sample Analysis at Mars investigation and allow the altitude of the homopause for the most abundant gases to be established.

  4. Field-aligned neutral wind bias correction scheme for global ionospheric modeling at midlatitudes by assimilating FORMOSAT-3/COSMIC hmF2 data under geomagnetically quiet conditions

    NASA Astrophysics Data System (ADS)

    Sun, Yang-Yi; Matsuo, Tomoko; Maruyama, Naomi; Liu, Jann-Yenq

    2015-04-01

    This study demonstrates the usage of a data assimilation procedure, which ingests the FORMOSAT-3/COSMIC (F3/C) hmF2 observations to correct the model wind biases to enhance the capability of the new global Ionosphere Plasmasphere Electrodynamics (IPE) model under geomagnetically quiet conditions. The IPE model is built upon the field line interhemispheric plasma model with a realistic geomagnetic field model and empirical model drivers. The hmF2 observed by the F3/C radio occultation technique is utilized to adjust global thermospheric field-aligned neutral winds (i.e., a component of the thermospheric neutral wind parallel to the magnetic field) at midlatitudes according to a linear relationship between time differentials of the field-aligned wind and hmF2. The adjusted winds are further applied to drive the IPE model. The comparison of the modeled electron density with the observations of F3/C and ground-based GPS receivers at the 2012 March equinox suggests that the modeled electron density can be significantly improved in the midlatitude regions of the Southern Hemisphere, if the wind correction scheme is applied. Moreover, the F3/C observation, the IPE model, and the wind bias correction scheme are applied to study the 2012 Southern Hemisphere Midlatitude Summer Nighttime Anomaly (southern MSNA)/Weddell Sea Anomaly (WSA) event at December solstice for examining the role of the neutral winds in controlling the longitudinal variation of the southern MSNA/WSA behavior. With the help of the wind bias correction scheme, the IPE model better tracks the F3/C-observed eastward movement of the southern MSNA/WSA feature. The apparent eastward movement of the southern MSNA/WSA features in the local time coordinate is primarily caused by the longitudinal variation in the declination angle of the geomagnetic field that controls the field-aligned projection of both geographic meridional and zonal components of the neutral wind. Both the IPE simulations and the F3/C

  5. Structural health monitoring of wind towers: residual fatigue life estimation

    NASA Astrophysics Data System (ADS)

    Benedetti, M.; Fontanari, V.; Battisti, L.

    2013-04-01

    In a recent paper (Benedetti et al 2011 Smart Mater. Struct. 20 055009), the authors investigated the possibility of detecting cracks in critical sites of onshore wind towers using a radial arrangement of strain sensors around the tower periphery in the vicinity of the base welded joint. Specifically, the strain difference between adjacent strain sensors is used as a damage indicator. The number of sensors to be installed is determined by the minimum crack size to be detected, which in turn depends on the expected extreme wind conditions and programmed inspection/repair schedule. In this companion paper, we address these issues by investigating possible strategies for residual fatigue life assessment and management of onshore wind towers once the crack has been detected. For this purpose, fracture mechanics tests are carried out using welded samples to quantify the resistance to fatigue crack growth as well as the elastic-plastic fracture toughness of the welded joint at the tower base. These material strength characteristics are used to estimate (i) the critical crack size for structural integrity on the basis of fracture toughness tests, elastoplastic finite element analyses and loading spectra under extreme wind conditions, (ii) the residual life before structural collapse, applying a frequency-domain method to typical in-service wind actions and wind directionality.

  6. Solar wind stream structure at large heliocentric distances Pioneer observations

    NASA Technical Reports Server (NTRS)

    Gazis, P. R.

    1987-01-01

    Time profiles and histograms of plasma data from Pioneers 10 and 11 are examined for the period between 1975 and 1983. During this time, Pioneer 10 traveled between a heliocentric distance of 8.7 and 30.4 AU. The velocity structure of the solar wind at these heliocentric distances is found to have one of two distinct forms: approximately 70 percent of the time the solar wind has a nearly flat velocity profile. Occasionally, this flat velocity profile is accompanied by quasi-periodic variations in density and in thermal speed consistent with the concept that the 'corotating interaction regions' which are produced by the interaction of high- and low-speed streams at intermediate heliocentric distances are replaced by 'pressure regions' in the outer heliosphere. The remaining 30 percent of the time the solar wind is marked by large (50-200 km/s) long-term (30-120 days) shifts in the average solar wind velocity.

  7. Role of neutral wind in the performance of artificial neural-network based TEC models at diverse longitudes in the low latitudes

    NASA Astrophysics Data System (ADS)

    Sur, D.; Ray, S.; Paul, A.

    2015-03-01

    The equatorial ionosphere is characterized by (i) large values of total electron content (TEC) and sharp latitudinal gradients of TEC, (ii) steep temporal variation of TEC, (iii) large diurnal variation of TEC, and (iv) postsunset secondary enhancement of TEC. These features cause major limitations in the accuracy of standard ionospheric TEC models in this region. Three artificial neural-network (ANN) based models have been developed based on real-time low-latitude TEC data along 77°E, 88°E, and 121°E longitudes in the region between the magnetic equator and locations beyond the northern crest of equatorial ionization anomaly to predict the vertical TEC values. ANN models have shown more accurate predictions than other standard ionospheric TEC models like International Reference Ionosphere, Parameterized Ionospheric Model, and NeQuick. The effects of the neutral wind in the variation of TEC are significant and have been incorporated as inputs to these ANN models. The outputs with neutral wind incorporated shows better correspondence with measured TEC than the models without neutral wind inputs. The longitudinally separated models have been used to find any longitudinal differences in TEC along equatorial regions. The causes behind the longitudinal differences in TEC and its diurnal variations in these regions have been explained in terms of the geomagnetic declination and inclination angles along with the role of zonal wind.

  8. Automated wind load characterization of wind turbine structures by embedded model updating

    NASA Astrophysics Data System (ADS)

    Swartz, R. Andrew; Zimmerman, Andrew T.; Lynch, Jerome P.

    2010-04-01

    The continued development of renewable energy resources is for the nation to limit its carbon footprint and to enjoy independence in energy production. Key to that effort are reliable generators of renewable energy sources that are economically competitive with legacy sources. In the area of wind energy, a major contributor to the cost of implementation is large uncertainty regarding the condition of wind turbines in the field due to lack of information about loading, dynamic response, and fatigue life of the structure expended. Under favorable circumstances, this uncertainty leads to overly conservative designs and maintenance schedules. Under unfavorable circumstances, it leads to inadequate maintenance schedules, damage to electrical systems, or even structural failure. Low-cost wireless sensors can provide more certainty for stakeholders by measuring the dynamic response of the structure to loading, estimating the fatigue state of the structure, and extracting loading information from the structural response without the need of an upwind instrumentation tower. This study presents a method for using wireless sensor networks to estimate the spectral properties of a wind turbine tower loading based on its measured response and some rudimentary knowledge of its structure. Structural parameters are estimated via model-updating in the frequency domain to produce an identification of the system. The updated structural model and the measured output spectra are then used to estimate the input spectra. Laboratory results are presented indicating accurate load characterization.

  9. Structures and properties of neutral gallium clusters: A theoretical investigation

    NASA Astrophysics Data System (ADS)

    Drebov, Nedko; Weigend, Florian; Ahlrichs, Reinhart

    2011-07-01

    A systematic and unbiased structure search based on a genetic algorithm in combination with density functional theory (DFT) procedures has been carried out to locate low-energy isomers of Ga_n up to n = 25. For the smaller clusters up to n = 8 results are checked by coupled cluster singles and doubles with perturbative triples corrections (CCSD(T)) employing a quadruple zeta type basis set. The CCSD(T) calculations confirm a ^3 Π _u ground state for the dimer. Ga_3 has a doublet ground state 0.2 eV below two quartet states, whereas two isoenergetic triplet states are predicted for Ga_4 with D_{4h} and a rhombus structure (D_{2h}). Three low-lying isomers with doublet electronic states are found for Ga_5: a W-structure (C_{2v}), a planar envelope (C_s) at 0.015 eV, and a non-planar envelope (C_1) 0.086 eV above the ground state. A triplet state for a trigonal prism (D_{3h}) and a singlet for an open prism (C_{2v}) are computed with virtually identical energy for Ga_6. The global minimum for Ga_7 is a capped trigonal prism (C_s) and that for Ga_8 a distorted cube in D_{2h}. DFT provides a fair agreement with CCSD(T), deviations in dissociation energies are up to 0.2 eV for n ⩽ 8. The structures for Ga_n are mostly irregular for n ⩾ 9, those for Ga_{12} to Ga_{17} can be derived from the truncated decahedron with D_{5h} symmetry though highly distorted by Jahn-Teller effects, for example. For Ga_{18} to Ga_{23} we find stacks of five- and six-membered rings as global minima, e.g., 5-1-5-1-6 for Ga_{18}. Ga_{24} and Ga_{25} consist of layers with packing sequence ABCBA similar to those found for clusters of aluminum. The most important feature of computed cohesive energies is a rapid increase with n: for Ga_{25} it reaches 2.46 eV, the experimental bulk value is 2.84 eV. Particularly stable clusters for Ga_n are seen for n = 7, 14, and 20.

  10. Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

    SciTech Connect

    Wu, Xueling; Zhou, Tongqing; Zhu, Jiang; Zhang, Baoshan; Georgiev, Ivelin; Wang, Charlene; Chen, Xuejun; Longo, Nancy S.; Louder, Mark; McKee, Krisha; O’Dell, Sijy; Perfetto, Stephen; Schmidt, Stephen D.; Shi, Wei; Wu, Lan; Yang, Yongping; Yang, Zhi-Yong; Yang, Zhongjia; Zhang, Zhenhai; Bonsignori, Mattia; Crump, John A.; Kapiga, Saidi H.; Sam, Noel E.; Haynes, Barton F.; Simek, Melissa; Burton, Dennis R.; Koff, Wayne C.; Doria-Rose, Nicole A.; Connors, Mark; Mullikin, James C.; Nabel, Gary J.; Roederer, Mario; Shapiro, Lawrence; Kwong, Peter D.; Mascola, John R.

    2013-03-04

    Antibody VRC01 is a human immunoglobulin that neutralizes about 90% of HIV-1 isolates. To understand how such broadly neutralizing antibodies develop, we used x-ray crystallography and 454 pyrosequencing to characterize additional VRC01-like antibodies from HIV-1-infected individuals. Crystal structures revealed a convergent mode of binding for diverse antibodies to the same CD4-binding-site epitope. A functional genomics analysis of expressed heavy and light chains revealed common pathways of antibody-heavy chain maturation, confined to the IGHV1-2*02 lineage, involving dozens of somatic changes, and capable of pairing with different light chains. Broadly neutralizing HIV-1 immunity associated with VRC01-like antibodies thus involves the evolution of antibodies to a highly affinity-matured state required to recognize an invariant viral structure, with lineages defined from thousands of sequences providing a genetic roadmap of their development.

  11. Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site.

    PubMed

    Bradley, Todd; Fera, Daniela; Bhiman, Jinal; Eslamizar, Leila; Lu, Xiaozhi; Anasti, Kara; Zhang, Ruijung; Sutherland, Laura L; Scearce, Richard M; Bowman, Cindy M; Stolarchuk, Christina; Lloyd, Krissey E; Parks, Robert; Eaton, Amanda; Foulger, Andrew; Nie, Xiaoyan; Karim, Salim S Abdool; Barnett, Susan; Kelsoe, Garnett; Kepler, Thomas B; Alam, S Munir; Montefiori, David C; Moody, M Anthony; Liao, Hua-Xin; Morris, Lynn; Santra, Sampa; Harrison, Stephen C; Haynes, Barton F

    2016-01-01

    Antibodies that neutralize autologous transmitted/founder (TF) HIV occur in most HIV-infected individuals and can evolve to neutralization breadth. Autologous neutralizing antibodies (nAbs) against neutralization-resistant (Tier-2) viruses are rarely induced by vaccination. Whereas broadly neutralizing antibody (bnAb)-HIV-Envelope structures have been defined, the structures of autologous nAbs have not. Here, we show that immunization with TF mutant Envs gp140 oligomers induced high-titer, V5-dependent plasma neutralization for a Tier-2 autologous TF evolved mutant virus. Structural analysis of autologous nAb DH427 revealed binding to V5, demonstrating the source of narrow nAb specificity and explaining the failure to acquire breadth. Thus, oligomeric TF Envs can elicit autologous nAbs to Tier-2 HIVs, but induction of bnAbs will require targeting of precursors of B cell lineages that can mature to heterologous neutralization. PMID:26725118

  12. Density, Velocity and Ionization Structure in Accretion-Disc Winds

    NASA Technical Reports Server (NTRS)

    Sonneborn, George (Technical Monitor); Long, Knox

    2004-01-01

    This was a project to exploit the unique capabilities of FUSE to monitor variations in the wind- formed spectral lines of the luminous, low-inclination, cataclysmic variables(CV) -- RW Sex. (The original proposal contained two additional objects but these were not approved.) These observations were intended to allow us to determine the relative roles of density and ionization state changes in the outflow and to search for spectroscopic signatures of stochastic small-scale structure and shocked gas. By monitoring the temporal behavior of blue-ward extended absorption lines with a wide range of ionization potentials and excitation energies, we proposed to track the changing physical conditions in the outflow. We planned to use a new Monte Carlo code to calculate the ionization structure of and radiative transfer through the CV wind. The analysis therefore was intended to establish the wind geometry, kinematics and ionization state, both in a time-averaged sense and as a function of time.

  13. A Review of Wind Project Financing Structures in the USA

    SciTech Connect

    Bolinger, Mark A; Harper, John; Karcher, Matthew

    2008-09-24

    The rapid pace of wind power development in the U.S. over the last decade has outstripped the ability of most project developers to provide adequate equity capital and make efficient use of project-related tax benefits. In response, the sector has created novel project financing structures that feature varying combinations of equity capital from project developers and third-party tax-oriented investors, and in some cases commercial debt. While their origins stem from variations in the financial capacity and business objectives of wind project developers, as well as the risk tolerances and objectives of equity and debt providers, each structure is, at its core, designed to manage project risk and allocate federal tax incentives to those entities that can use them most efficiently. This article surveys the six principal financing structures through which most new utility-scale wind projects (excluding utility-owned projects) in the U.S. have been financed from 1999 to the present. These structures include simple balance-sheet finance, several varieties of all-equity special allocation partnership 'flip' structures, and two leveraged structures. In addition to describing each structure's mechanics, the article also discusses its rationale for use, the types of investors that find it appealing and why, and its relative frequency of use in the market. The article concludes with a generalized summary of how a developer might choose one structure over another.

  14. Some Notes on the Determination of the Stick-Free Neutral Point from Wind-Tunnel Data

    NASA Technical Reports Server (NTRS)

    Schuldenfrei, Marvin

    1944-01-01

    Two graphical methods are presented for determining the stick-free neutral point, and they are extensions of the methods commonly used to determine the stick-free neutral point. A mathematical formula for computing the stick-free neutral point is also given. These methods may be applied to determine approximately the increase in tail size necessary to shift the neutral point (stick fixed or free) to any desired location on an airplane having inadequate longitudinal stability.

  15. The bow shock structure of IRS 7 - Wind-wind collision near the Galactic center

    NASA Technical Reports Server (NTRS)

    Yusef-Zadeh, Farhad; Melia, Fulvio

    1992-01-01

    New structural details of ionized gas associated with IRS 7, a mass-losing supergiant near the Galactic center, are reported, and radio continuum and theoretical maps are compared. High-resolution multiconfiguration VLA observations of IRS 7 reveal ionized gas with a bow shock structure at a wavelength of 2 cm. The apex of the bow shock is facing more toward the cluster of blue stellar objects, known as IRS 16, than Sgr A*, the compact nonthermal source near the Galaxy's dynamical center. It is inferred that the shape of the mass-losing envelope of IRS 7 is influenced by Galactic winds from IRS 16. It is concluded from a comparison of the morphology of the ionized envelope of IRS 7 with simple theoretical modeling of the bow shock structure that the shape of the shock results from the collision between the Galactic center and stellar winds rather than from the motion of IRS 7 through the interstellar medium.

  16. Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody

    PubMed Central

    Ku, Zhiqiang; Zuo, Teng; Kong, Liangliang; Zhang, Chao; Shi, Jinping; Liu, Qingwei; Chen, Tan; Zhang, Yingyi; Jiang, Wen; Zhang, Linqi; Huang, Zhong; Cong, Yao

    2016-01-01

    Enterovirus 71 (EV71) is the main pathogen responsible for hand, foot and mouth disease with severe neurological complications and even death in young children. We have recently identified a highly potent anti-EV71 neutralizing monoclonal antibody, termed D5. Here we investigated the structural basis for recognition of EV71 by the antibody D5. Four three-dimensional structures of EV71 particles in complex with IgG or Fab of D5 were reconstructed by cryo-electron microscopy (cryo-EM) single particle analysis all at subnanometer resolutions. The most critical EV71 mature virion-Fab structure was resolved to a resolution of 4.8 Å, which is rare in cryo-EM studies of virus-antibody complex so far. The structures reveal a bivalent binding pattern of D5 antibody across the icosahedral 2-fold axis on mature virion, suggesting that D5 binding may rigidify virions to prevent their conformational changes required for subsequent RNA release. Moreover, we also identified that the complementary determining region 3 (CDR3) of D5 heavy chain directly interacts with the extremely conserved VP1 GH-loop of EV71, which was validated by biochemical and virological assays. We further showed that D5 is indeed able to neutralize a variety of EV71 genotypes and strains. Moreover, D5 could potently confer protection in a mouse model of EV71 infection. Since the conserved VP1 GH-loop is involved in EV71 binding with its uncoating receptor, the scavenger receptor class B, member 2 (SCARB2), the broadly neutralizing ability of D5 might attribute to its inhibition of EV71 from binding SCARB2. Altogether, our results elucidate the structural basis for the binding and neutralization of EV71 by the broadly neutralizing antibody D5, thereby enhancing our understanding of antibody-based protection against EV71 infection. PMID:26938634

  17. Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody.

    PubMed

    Ye, Xiaohua; Fan, Chen; Ku, Zhiqiang; Zuo, Teng; Kong, Liangliang; Zhang, Chao; Shi, Jinping; Liu, Qingwei; Chen, Tan; Zhang, Yingyi; Jiang, Wen; Zhang, Linqi; Huang, Zhong; Cong, Yao

    2016-03-01

    Enterovirus 71 (EV71) is the main pathogen responsible for hand, foot and mouth disease with severe neurological complications and even death in young children. We have recently identified a highly potent anti-EV71 neutralizing monoclonal antibody, termed D5. Here we investigated the structural basis for recognition of EV71 by the antibody D5. Four three-dimensional structures of EV71 particles in complex with IgG or Fab of D5 were reconstructed by cryo-electron microscopy (cryo-EM) single particle analysis all at subnanometer resolutions. The most critical EV71 mature virion-Fab structure was resolved to a resolution of 4.8 Å, which is rare in cryo-EM studies of virus-antibody complex so far. The structures reveal a bivalent binding pattern of D5 antibody across the icosahedral 2-fold axis on mature virion, suggesting that D5 binding may rigidify virions to prevent their conformational changes required for subsequent RNA release. Moreover, we also identified that the complementary determining region 3 (CDR3) of D5 heavy chain directly interacts with the extremely conserved VP1 GH-loop of EV71, which was validated by biochemical and virological assays. We further showed that D5 is indeed able to neutralize a variety of EV71 genotypes and strains. Moreover, D5 could potently confer protection in a mouse model of EV71 infection. Since the conserved VP1 GH-loop is involved in EV71 binding with its uncoating receptor, the scavenger receptor class B, member 2 (SCARB2), the broadly neutralizing ability of D5 might attribute to its inhibition of EV71 from binding SCARB2. Altogether, our results elucidate the structural basis for the binding and neutralization of EV71 by the broadly neutralizing antibody D5, thereby enhancing our understanding of antibody-based protection against EV71 infection. PMID:26938634

  18. Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

    SciTech Connect

    Zhou, Tongqing; Georgiev, Ivelin; Wu, Xueling; Yang, Zhi-Yong; Dai, Kaifan; Finzi, Andrés; Kwon, Young Do; Scheid, Johannes F.; Shi, Wei; Xu, Ling; Yang, Yongping; Zhu, Jiang; Nussenzweig, Michel C.; Sodroski, Joseph; Shapiro, Lawrence; Nabel, Gary J.; Mascola, John R.; Kwong, Peter D.

    2010-08-26

    During HIV-1 infection, antibodies are generated against the region of the viral gp120 envelope glycoprotein that binds CD4, the primary receptor for HIV-1. Among these antibodies, VRC01 achieves broad neutralization of diverse viral strains. We determined the crystal structure of VRC01 in complex with a human immunodeficiency virus HIV-1 gp120 core. VRC01 partially mimics CD4 interaction with gp120. A shift from the CD4-defined orientation, however, focuses VRC01 onto the vulnerable site of initial CD4 attachment, allowing it to overcome the glycan and conformational masking that diminishes the neutralization potency of most CD4-binding-site antibodies. To achieve this recognition, VRC01 contacts gp120 mainly through immunoglobulin V-gene regions substantially altered from their genomic precursors. Partial receptor mimicry and extensive affinity maturation thus facilitate neutralization of HIV-1 by natural human antibodies.

  19. The Molecular Clock of Neutral Evolution Can Be Accelerated or Slowed by Asymmetric Spatial Structure

    PubMed Central

    Allen, Benjamin; Sample, Christine; Dementieva, Yulia; Medeiros, Ruben C.; Paoletti, Christopher; Nowak, Martin A.

    2015-01-01

    Over time, a population acquires neutral genetic substitutions as a consequence of random drift. A famous result in population genetics asserts that the rate, K, at which these substitutions accumulate in the population coincides with the mutation rate, u, at which they arise in individuals: K = u. This identity enables genetic sequence data to be used as a “molecular clock” to estimate the timing of evolutionary events. While the molecular clock is known to be perturbed by selection, it is thought that K = u holds very generally for neutral evolution. Here we show that asymmetric spatial population structure can alter the molecular clock rate for neutral mutations, leading to either Ku. Our results apply to a general class of haploid, asexually reproducing, spatially structured populations. Deviations from K = u occur because mutations arise unequally at different sites and have different probabilities of fixation depending on where they arise. If birth rates are uniform across sites, then K ≤ u. In general, K can take any value between 0 and Nu. Our model can be applied to a variety of population structures. In one example, we investigate the accumulation of genetic mutations in the small intestine. In another application, we analyze over 900 Twitter networks to study the effect of network topology on the fixation of neutral innovations in social evolution. PMID:25719560

  20. Understanding the structural transformation, stability of medium-sized neutral and charged silicon clusters

    PubMed Central

    Ding, Li Ping; Zhang, Fang Hui; Zhu, Yong Sheng; Lu, Cheng; Kuang, Xiao Yu; Lv, Jian; Shao, Peng

    2015-01-01

    The structural and electronic properties for the global minimum structures of medium-sized neutral, anionic and cationic Sinμ (n = 20–30, μ = 0, −1 and +1) clusters have been studied using an unbiased CALYPSO structure searching method in conjunction with first-principles calculations. A large number of low-lying isomers are optimized at the B3PW91/6-311 + G* level of theory. Harmonic vibrational analysis has been performed to assure that the optimized geometries are stable. The growth behaviors clearly indicate that a structural transition from the prolate to spherical-like geometries occurs at n = 26 for neutral silicon clusters, n = 27 for anions and n = 25 for cations. These results are in good agreement with the available experimental and theoretical predicted findings. In addition, no significant structural differences are observed between the neutral and cation charged silicon clusters with n = 20–24, both of them favor prolate structures. The HOMO-LUMO gaps and vertical ionization potential patterns indicate that Si22 is the most chemical stable cluster, and its dynamical stability is deeply discussed by the vibrational spectra calculations. PMID:26526519

  1. Structural testing of the North Wind 250 composite rotor joint

    SciTech Connect

    Musial, W; Link, H; Coleman, C

    1994-05-01

    The North Wind 250 wind turbine is under development at Northern Power Systems (NPS) in Moretown, VT. The turbine uses a unique, flow-through, teetered-rotor design. This design eliminates structural discontinuities at the blade/hub interface by fabricating the rotor as one continuous structural element. To accomplish this, the two blade spars are joined at the center of the rotor using a proprietary bonding technique. Fatigue tests were conducted on the full-scale rotor joint at the National Renewable Energy Laboratory (NREL). Subsequent tests are now underway to test the full-scale rotor and hub assembly to verify the design assumptions. The test articles were mounted in dedicated test fixtures. For the joint test, a constant moment was generated across the joint and parent material. Hydraulic actuators applied sinusoidal loading to the test article at levels equivalent to 90% of the extreme wind load for over one million cycles. When the loading was increased to 112% of the extreme wind load, the joint failed by buckling. Strain levels were monitored at 14 locations inside and outside of the blade joint during the test. The tests were used to qualify this critical element of the rotor for field testing and to provide information needed to improve the structural design of the joint.

  2. Effects of solar wind speed on the secondary energetic neutral source of the Interstellar Boundary Explorer ribbon

    NASA Astrophysics Data System (ADS)

    Zirnstein, E. J.; Funsten, H. O.; Heerikhuisen, J.; McComas, D. J.

    2016-02-01

    The Interstellar Boundary EXplorer (IBEX) ribbon is an intense energetic neutral atom (ENA) emission feature encircling the sky, spanning energies ≤0.5-6 keV. The ribbon may be produced by the "secondary ENA" mechanism, where ENAs emitted from a source plasma population inside the heliosphere propagate outside the heliopause, undergo two charge-exchange events, and become secondary ENAs that may be directed back toward Earth and detected by IBEX. In this scenario, the source plasma population is governed by the interaction of the solar wind (SW) with the interstellar medium and is thus sensitive to the global SW properties. Moreover, this scenario predicts that the distance to the source of secondary ENAs depends on the ENA energy and SW speed, which in turn may affect the shape of the ribbon. In this paper, we use a computational model of the heliosphere with simplified SW boundary conditions to analyze the influence of ENA energy and SW speed, independent of time and latitude, on the global spatial and geometric properties of the ribbon. We find a strong dependence of the simulated ribbon energy spectrum and spatial symmetry on SW speed and ENA energy, and only a slight dependence on ribbon geometry. Our results suggest a significant number of primary ENAs from the inner heliosheath may contribute to the pickup ion source population outside the heliopause, depending on the ENA energy and SW speed. The lack of variation in the simulated ribbon center as a function of ENA energy and SW speed, in contrast to the observations, implies that the asymmetry of the SW plays an important role in determining the position of the ribbon. Comparisons to the IBEX data also signify the ribbon's dependence on the properties of the local interstellar medium, particularly the interstellar magnetic field.

  3. Structural integrity of wind tunnel wooden fan blades

    NASA Technical Reports Server (NTRS)

    Young, Clarence P., Jr.; Wingate, Robert T.; Rooker, James R.; Mort, Kenneth W.; Zager, Harold E.

    1991-01-01

    Information is presented which was compiled by the NASA Inter-Center Committee on Structural Integrity of Wooden Fan Blades and is intended for use as a guide in design, fabrication, evaluation, and assurance of fan systems using wooden blades. A risk assessment approach for existing NASA wind tunnels with wooden fan blades is provided. Also, state of the art information is provided for wooden fan blade design, drive system considerations, inspection and monitoring methods, and fan blade repair. Proposed research and development activities are discussed, and recommendations are provided which are aimed at future wooden fan blade design activities and safely maintaining existing NASA wind tunnel fan blades. Information is presented that will be of value to wooden fan blade designers, fabricators, inspectors, and wind tunnel operations personnel.

  4. Effects of structure flexibility on horizontal axis wind turbine performances

    NASA Astrophysics Data System (ADS)

    Coiro, D. P.; Daniele, E.; Scherillo, F.

    2013-10-01

    This work illustrates the effects of flexibility of rotor blades and turbine tower on the performances of an horizontal axis wind turbine (HAWT) designed by our ADAG research group, by means of several example applied on a recent project for a active pitch controlled upwind 60 kW HAWT. The influence of structural flexibility for blade only, tower only and blade coupled with tower configuration is investigated using an aero-elastic computer-aided engineering (CAE) tool for horizontal axis wind turbines named FAST developed at National Renewable Energy Laboratory (NREL) of USA. For unsteady inflow conditions in front of the isolated HAWT the performances in rigid and flexible operation mode are computed and compared in order to illustrate the limitation included within a classical rigid body approach to wind turbine simulation.

  5. Searching for large scale structures over Lake Geneva using Wind-Lidars

    NASA Astrophysics Data System (ADS)

    Calaf, M.; Hultmark, M.; Oldroyd, H. J.; Parlange, M. B.

    2012-12-01

    Large-scale coherent structures in turbulent boundary layers have received much attention in laboratory studies during the last decade. Kim & Adrian (1999) found that the structures can extend up to 15 times the boundary layer thickness and that they are responsible for about 50% of the total turbulent kinetic energy. Thus, understanding the details of these large-scale structures is of great importance, both for fluid-structure interaction and energy harvesting techniques. Hutchins & Marusic (2007) conducted a very complete study of the large-scale structures where they also measured in the atmospheric surface layer (ASL). By using rakes of hot-wires in a near-ideal neutral boundary layer they were able to find evidence that these large structures exist also in the ASL, and the scaling of them is very similar to that shown in wind tunnel tests. However, Taylor's hypothesis is needed to convert time to space, when using hot-wire data to investigate the spatial structures. For unraveling the true spatial distribution of these structures one need to use distributed sensors or remote sensing technologies. Here, data taken over lake Geneva during the super-cold winter from 2012 will be presented. Unique photographs clearly illustrating the organization and coherency of these structures, together with data obtained from wind LIDARs will be shown. The field observations provide clear evidence of the existence of these large-scale structures in the atmospheric boundary layer (ABL) above the lake and their size to be correlated with the height of the ABL itself. The LIDAR data provide a unique possibility to compare space and time data to each other, allowing us to explore these structures from a spatial and temporal perspective.

  6. Simultaneous Observations of Electric Fields, Current Density, Plasma Density, and Neutral Winds During Two Sounding Rocket Experiments Launched from Wallops Island into Strong Daytime Dynamo Currents

    NASA Astrophysics Data System (ADS)

    Pfaff, R. F., Jr.; Rowland, D. E.; Klenzing, J.; Freudenreich, H. T.; Martin, S. C.; Abe, T.; Habu, H.; Yamamoto, M. Y.; Watanabe, S.; Yamamoto, M.; Yokoyama, T.; Kakinami, Y.; Yamazaki, Y.; Larsen, M. F.; Hurd, L.; Clemmons, J. H.; Bishop, R. L.; Walterscheid, R. L.; Fish, C. S.; Bullett, T. W.; Mabie, J. J.; Murphy, N.; Angelopoulos, V.; Leinweber, H. K.; Bernal, I.; Chi, P. J.

    2015-12-01

    To investigate the ion-neutral coupling that creates the global electrical daytime "dynamo" currents in the mid-latitude, lower ionosphere, NASA carried out two multiple sounding rocket experiments from Wallops Island, VA on July 10, 2011 (14:00 UT, 10:00 LT) and July 4, 2013 (14:31 UT, 10:31 LT). The rockets were launched in the presence of well-defined, westward Hall currents observed on the ground with ΔH values of ­-25 nT and -30 nT, respectively, as well as a well-defined, daytime ionospheric density observed by the VIPIR ionosonde at Wallops. During the 2011 experiment, a narrow, intense sporadic-E layer was observed near 102 km. Each experiment consisted of a pair of rockets launched 15 sec apart. The first rocket of each pair carried instruments to measure DC electric and magnetic fields, as well as the ambient plasma and neutral gases and attained apogees of 158 km and 135 km in the 2011 and 2013 experiments, respectively. The second rocket of each pair carried canisters which released a lithium vapor trail along the upleg to illuminate neutral winds in the upper atmosphere. This daytime vapor trail technology was developed jointly by researchers at JAXA and Clemson University. In the second experiment, the lithium release was clearly visible in cameras with infrared filters operated by US and Japanese researchers in a NASA airplane at 9.6 km altitude. The observed wind profiles reached speeds of 100 m/s with strong shears with respect to altitude and were consistent with an independent derivation of the wind from the ionization gauge sensor suite on the instrumented rocket. The "vapor trail" rockets, which also included a falling sphere, attained apogees of 150 km and 143 km in the 2011 and 2013 experiments, respectively. By measuring the current density, conductivity, DC electric fields, and neutral winds, we solve the dynamo equation as a function of altitude, revealing the different contributions to the lower E-region currents. We find that the DC

  7. Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization.

    PubMed

    Guan, Jian; Bywaters, Stephanie M; Brendle, Sarah A; Lee, Hyunwook; Ashley, Robert E; Makhov, Alexander M; Conway, James F; Christensen, Neil D; Hafenstein, Susan

    2015-09-01

    Cryo-electron microscopy (cryo-EM) was used to solve the structures of human papillomavirus type 16 (HPV16) complexed with fragments of antibody (Fab) from three different neutralizing monoclonals (mAbs): H16.1A, H16.14J, and H263.A2. The structure-function analysis revealed predominantly monovalent binding of each Fab with capsid interactions that involved multiple loops from symmetry related copies of the major capsid protein. The residues identified in each Fab-virus interface map to a conformational groove on the surface of the capsomer. In addition to the known involvement of the FG and HI loops, the DE loop was also found to constitute the core of each epitope. Surprisingly, the epitope mapping also identified minor contributions by EF and BC loops. Complementary immunological assays included mAb and Fab neutralization. The specific binding characteristics of mAbs correlated with different neutralizing behaviors in pre- and post-attachment neutralization assays. PMID:25996608

  8. FORMATION OF COLD FILAMENTARY STRUCTURE FROM WIND-BLOWN SUPERBUBBLES

    SciTech Connect

    Ntormousi, Evangelia; Burkert, Andreas; Fierlinger, Katharina; Heitsch, Fabian

    2011-04-10

    The expansion and collision of two wind-blown superbubbles is investigated numerically. Our models go beyond previous simulations of molecular cloud formation from converging gas flows by exploring this process with realistic flow parameters, sizes, and timescales. The superbubbles are blown by time-dependent winds and supernova explosions, calculated from population synthesis models. They expand into a uniform or turbulent diffuse medium. We find that dense, cold gas clumps and filaments form naturally in the compressed collision zone of the two superbubbles. Their shapes resemble the elongated, irregular structure of observed cold, molecular gas filaments, and clumps. At the end of the simulations, between 65% and 80% of the total gas mass in our simulation box is contained in these structures. The clumps are found in a variety of physical states, ranging from pressure equilibrium with the surrounding medium to highly underpressured clumps with large irregular internal motions and structures which are rotationally supported.

  9. THE MULTIPHASE STRUCTURE AND POWER SOURCES OF GALACTIC WINDS IN MAJOR MERGERS

    SciTech Connect

    Rupke, David S. N.; Veilleux, Sylvain

    2013-05-01

    Massive, galaxy-scale outflows are known to be ubiquitous in major mergers of disk galaxies in the local universe. In this paper, we explore the multiphase structure and power sources of galactic winds in six ultraluminous infrared galaxies (ULIRGs) at z < 0.06 using deep integral field spectroscopy with the Gemini Multi-Object Spectrograph (GMOS) on Gemini North. We probe the neutral, ionized, and dusty gas phases using Na I D, strong emission lines ([O I], H{alpha}, and [N II]), and continuum colors, respectively. We separate outflow motions from those due to rotation and tidal perturbations, and find that all of the galaxies in our sample host high-velocity flows on kiloparsec scales. The properties of these outflows are consistent with multiphase (ionized, neutral, and dusty) collimated bipolar winds emerging along the minor axis of the nuclear disk to scales of 1-2 kpc. In two cases, these collimated winds take the form of bipolar superbubbles, identified by clear kinematic signatures. Less collimated (but still high-velocity) flows are also present on scales up to 5 kpc in most systems. The three galaxies in our sample with obscured QSOs host higher velocity outflows than those in the three galaxies with no evidence for an active galactic nucleus. The peak outflow velocity in each of the QSOs is in the range 1450-3350 km s{sup -1}, and the highest velocities (2000-3000 km s{sup -1}) are seen only in ionized gas. The outflow energy and momentum in the QSOs are difficult to produce from a starburst alone, but are consistent with the QSO contributing significantly to the driving of the flow. Finally, when all gas phases are accounted for, the outflows are massive enough to provide negative feedback to star formation.

  10. Potential Structure and Fluctuations of Plasma Hole with Quasi-Neutrality Breaking

    NASA Astrophysics Data System (ADS)

    Yoshimura, Shinji; Okamoto, Atsushi; Tanaka, Masayoshi

    2003-10-01

    Spontaneous formation of a stationary vortex structure with density depletion around the central axis (plasma hole) has been observed in an ECR plasma produced in the HYPER-I device (30 cm diameter, 200 cm length). So far it has been found that the ion flow structure of the plasma hole is identified as a dissipative vortex in viscous fluids (Burgers vortex), which has a Gaussian vorticity distribution. It has been also revealed that the potential has a bell-shaped axisymmetric structure localized inside the core region, in which its maximum value exceeds 5T_ e. Degree of quasi-neutrality breaking has been evaluated using Poisson's equation, and it has been found that the normalized deviation of the charge is exceptionally large in the core region. Hence the plasma hole can be construed as the structure of a nonneutral core surrounded by a quasi-neutral plasma. It is of great interest to study the fluctuations in the interfacial layer between the nonneutral and the quasi-neutral plasma. The results of preliminary experiments show that the pronounced fluctuations in potential exist in the interfacial layer. Further investigation of the potential fluctuation will be presented.

  11. Field investigation of a wake structure downwind of a VAWT (vertical-axis wind turbine) in a wind farm array

    SciTech Connect

    Liu, H.T.; Buck, J.W.; Germain, A.C.; Hinchee, M.E.; Solt, T.S.; LeRoy, G.M.; Srnsky, R.A.

    1988-09-01

    The effects of upwind turbine wakes on the performance of a FloWind 17-m vertical-axis wind turbine (VAWT) were investigated through a series of field experiments conducted at the FloWind wind farm on Cameron Ridge, Tehachapi, California. From the field measurements, we derived the velocity and power/energy deficits under various turbine on/off configurations. Much information was provided to characterize the structure of VAWT wakes and to assess their effects on the performance of downwind turbines. A method to estimate the energy deficit was developed based on the measured power deficit and the wind speed distributions. This method may be adopted for other turbine types and sites. Recommendations are made for optimizing wind farm design and operations, as well as for wind energy management. 17 refs., 66 figs., 6 tabs.

  12. Field investigation of a wake structure downwind of a VANT (Vertical-Axis Wind Turbine) in a wind farm array

    NASA Astrophysics Data System (ADS)

    Liu, H. T.; Buck, J. W.; Germain, A. C.; Hinchee, M. E.; Solt, T. S.; Leroy, G. M.; Srnsky, R. A.

    1988-09-01

    The effects of upwind turbine wakes on the performance of a FloWind 17-m vertical-axis wind turbine (VAWT) were investigated through a series of field experiments conducted at the FloWind wind farm on Cameron Ridge, Tehachapi, California. From the field measurements, we derived the velocity and power/energy deficits under various turbine on/off configurations. Much information was provided to characterize the structure of VAWT wakes and to assess their effects on the performance of downwind turbines. A method to estimate the energy deficit was developed based on the measured power deficit and the wind speed distributions. This method may be adopted for other turbine types and sites. Recommendations are made for optimizing wind farm design and operations, as well as for wind energy management.

  13. Structures and spectral variations of the outer heliosphere in IBEX energetic neutral atom maps.

    PubMed

    Funsten, H O; Allegrini, F; Crew, G B; DeMajistre, R; Frisch, P C; Fuselier, S A; Gruntman, M; Janzen, P; McComas, D J; Möbius, E; Randol, B; Reisenfeld, D B; Roelof, E C; Schwadron, N A

    2009-11-13

    The Interstellar Boundary Explorer (IBEX) has obtained all-sky images of energetic neutral atoms emitted from the heliosheath, located between the solar wind termination shock and the local interstellar medium (LISM). These flux maps reveal distinct nonthermal (0.2 to 6 kilo-electron volts) heliosheath proton populations with spectral signatures ordered predominantly by ecliptic latitude. The maps show a globally distributed population of termination-shock-heated protons and a superimposed ribbonlike feature that forms a circular arc in the sky centered on ecliptic coordinate (longitude lambda, latitude beta) = (221 degrees, 39 degrees), probably near the direction of the LISM magnetic field. Over the IBEX energy range, the ribbon's nonthermal ion pressure multiplied by its radial thickness is in the range of 70 to 100 picodynes per square centimeter AU (AU, astronomical unit), which is significantly larger than the 30 to 60 picodynes per square centimeter AU of the globally distributed population. PMID:19833918

  14. Neutral Hydrogen Structures Trace Dust Polarization Angle: Implications for Cosmic Microwave Background Foregrounds

    NASA Astrophysics Data System (ADS)

    Clark, S. E.; Hill, J. Colin; Peek, J. E. G.; Putman, M. E.; Babler, B. L.

    2015-12-01

    Using high-resolution data from the Galactic Arecibo L-Band Feed Array HI (GALFA-Hi) survey, we show that linear structure in Galactic neutral hydrogen (Hi) correlates with the magnetic field orientation implied by Planck 353 GHz polarized dust emission. The structure of the neutral interstellar medium is more tightly coupled to the magnetic field than previously known. At high Galactic latitudes, where the Planck data are noise dominated, the Hi data provide an independent constraint on the Galactic magnetic field orientation, and hence the local dust polarization angle. We detect strong cross-correlations between template maps constructed from estimates of dust intensity combined with either Hi-derived angles, starlight polarization angles, or Planck 353 GHz angles. The Hi data thus provide a new tool in the search for inflationary gravitational wave B -mode polarization in the cosmic microwave background, which is currently limited by dust foreground contamination.

  15. Neutral Hydrogen Structures Trace Dust Polarization Angle: Implications for Cosmic Microwave Background Foregrounds.

    PubMed

    Clark, S E; Hill, J Colin; Peek, J E G; Putman, M E; Babler, B L

    2015-12-11

    Using high-resolution data from the Galactic Arecibo L-Band Feed Array HI (GALFA-Hi) survey, we show that linear structure in Galactic neutral hydrogen (Hi) correlates with the magnetic field orientation implied by Planck 353 GHz polarized dust emission. The structure of the neutral interstellar medium is more tightly coupled to the magnetic field than previously known. At high Galactic latitudes, where the Planck data are noise dominated, the Hi data provide an independent constraint on the Galactic magnetic field orientation, and hence the local dust polarization angle. We detect strong cross-correlations between template maps constructed from estimates of dust intensity combined with either Hi-derived angles, starlight polarization angles, or Planck 353 GHz angles. The Hi data thus provide a new tool in the search for inflationary gravitational wave B-mode polarization in the cosmic microwave background, which is currently limited by dust foreground contamination. PMID:26705622

  16. Electronic structure of metallic alloys using charge-neutral atomic spheres

    SciTech Connect

    Singh, P.P.; Gonis, A. )

    1994-01-15

    Based on the idea of charge-neutral atoimc spheres we have calculated the electronic structure of ordered and disordered Cu-Zn, Ni-Pt, and Al-Li alloys using the linear-muffin-tin-orbital (LMTO) method and the Korringa-Kohn-Rostoker coherent potential approximation (KKR CPA) method in the atomic-sphere approximation (ASA), respectively. The equilibrium lattice constants and the formation energies of ordered alloys obtained with the LMTO-ASA method show that the calculations done with charge-neutral atomic spheres are closer to the experimental results than the conventional equivolume atomic-sphere-type calculations. In the case of disordered alloys, we find that charge-neutral atomic spheres are essential for the stability of these alloys within the KKR-ASA CPA method where the Madelung-type contribution is neglected. Our results clearly indicate that for disordered alloys any future implementation of a full-potential method within the single-site CPA should be carried out with charge-neutral cells rather than the Wigner-Seitz cells.

  17. Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors

    PubMed Central

    Zhou, Tongqing; Lynch, Rebecca M.; Chen, Lei; Acharya, Priyamvada; Wu, Xueling; Doria-Rose, Nicole A.; Joyce, M. Gordon; Lingwood, Daniel; Soto, Cinque; Bailer, Robert T.; Ernandes, Michael J.; Kong, Rui; Longo, Nancy S.; Louder, Mark K.; McKee, Krisha; O’Dell, Sijy; Schmidt, Stephen D.; Tran, Lillian; Yang, Zhongjia; Druz, Aliaksandr; Luongo, Timothy S.; Moquin, Stephanie; Srivatsan, Sanjay; Yang, Yongping; Zhang, Baoshan; Zheng, Anqi; Pancera, Marie; Kirys, Tatsiana; Georgiev, Ivelin S.; Gindin, Tatyana; Peng, Hung-Pin; Yang, An-Suei; Mullikin, James C.; Gray, Matthew D.; Stamatatos, Leonidas; Burton, Dennis R.; Koff, Wayne C.; Cohen, Myron S.; Haynes, Barton F.; Casazza, Joseph P.; Connors, Mark; Corti, Davide; Lanzavecchia, Antonio; Sattentau, Quentin J.; Weiss, Robin A.; West, Anthony P.; Bjorkman, Pamela J.; Scheid, Johannes F.; Nussenzweig, Michel C.; Shapiro, Lawrence; Mascola, John R.; Kwong, Peter D.

    2015-01-01

    The site on the HIV-1 gp120 glycoprotein that binds the CD4 receptor is recognized by broadly reactive antibodies, several of which neutralize over 90% of HIV-1 strains. To understand how antibodies achieve such neutralization, we isolated CD4-binding-site (CD4bs) antibodies and analyzed 16 co-crystal structures –8 determined here– of CD4bs antibodies from 14 donors. The 16 antibodies segregated by recognition mode and developmental ontogeny into two types: CDR H3-dominated and VH-gene-restricted. Both could achieve greater than 80% neutralization breadth, and both could develop in the same donor. Although paratope chemistries differed, all 16 gp120-CD4bs antibody complexes showed geometric similarity, with antibody-neutralization breadth correlating with antibody-angle of approach relative to the most effective antibody of each type. The repertoire for effective recognition of the CD4 supersite thus comprises antibodies with distinct paratopes arrayed about two optimal geometric orientations, one achieved by CDR H3 ontogenies and the other achieved by VH-gene-restricted ontogenies. PMID:26004070

  18. Stochastic Demography and the Neutral Substitution Rate in Class-Structured Populations

    PubMed Central

    Lehmann, Laurent

    2014-01-01

    The neutral rate of allelic substitution is analyzed for a class-structured population subject to a stationary stochastic demographic process. The substitution rate is shown to be generally equal to the effective mutation rate, and under overlapping generations it can be expressed as the effective mutation rate in newborns when measured in units of average generation time. With uniform mutation rate across classes the substitution rate reduces to the mutation rate. PMID:24594520

  19. Structure of the neutral upper atmosphere of Mars - Results from Viking 1 and Viking 2

    NASA Technical Reports Server (NTRS)

    Nier, A. O.; Mcelroy, M. B.

    1976-01-01

    Neutral mass spectrometers carried on the aeroshells of Viking 1 and Viking 2 indicate that carbon dioxide is the major constituent of the Martian atmosphere over the height range 120 to 200 kilometers. The atmosphere contains detectable concentrations of nitrogen, argon, carbon monoxide, molecular oxygen, atomic oxygen, and nitric oxide. The upper atmosphere exhibits a complex and variable thermal structure and is well mixed to heights in excess of 120 kilometers.

  20. Hyperfine structure and isotope shifts of transitions in neutral and singly ionized ytterbium

    NASA Technical Reports Server (NTRS)

    Berends, R. W.; Maleki, L.

    1992-01-01

    The present experimental investigation of the hyperfine structure and isotopic shifts of transitions in neutral and singly-ionized Yb, which constitute a system of some interest to microwave-frequency standards, used counterpropagating pump and probe laser beams directed through a hollow-cathode discharge lamp. The results obtained are in agreement with previous measurements except in the case of the Yb-173(+) 6 2P0 sub 3/2 state, which is more accurately determined.

  1. Community investment in wind farms: funding structure effects in wind energy infrastructure development.

    PubMed

    Beery, Joshua A; Day, Jennifer E

    2015-03-01

    Wind energy development is an increasingly popular form of renewable energy infrastructure in rural areas. Communities generally perceive socioeconomic benefits accrue and that community funding structures are preferable to corporate structures, yet lack supporting quantitative data to inform energy policy. This study uses the Everpower wind development, to be located in Midwestern Ohio, as a hypothetical modeling environment to identify and examine socioeconomic impact trends arising from corporate, community and diversified funding structures. Analysis of five National Renewable Energy Laboratory Jobs and Economic Development Impact models incorporating local economic data and review of relevant literature were conducted. The findings suggest that community and diversified funding structures exhibit 40-100% higher socioeconomic impact levels than corporate structures. Prioritization of funding sources and retention of federal tax incentives were identified as key elements. The incorporation of local shares was found to mitigate the negative effects of foreign private equity, local debt financing increased economic output and opportunities for private equity investment were identified. The results provide the groundwork for energy policies focused to maximize socioeconomic impacts while creating opportunities for inclusive economic participation and improved social acceptance levels fundamental to the deployment of renewable energy technology. PMID:25621885

  2. Mirror Mode structures in the solar wind observed by STEREO

    NASA Astrophysics Data System (ADS)

    Lizeth Enríquez-Rivera, Olivia; Blanco-Cano, Xochitl; Russell, C. T.; Jian, Lan; Luhmann, Janet G.

    Mirror mode structures have been found in the solar wind at various heliocentric distances with different missions. Recently, STEREO has observed mirror mode waves present as trains of holes and also as humps in the magnetic field strength. In some cases mirror mode trains last very long periods of time and have been therefore called "mirror mode storms". We present case studies of mirror mode structures (storms and trains) observed in the solar wind using STEREO data in three different locations: in the downstream region of the forward shock of a SIR, inside a SIR far from the forward shock and also in the ambient solar wind. In order to make a formal identification of the mirror mode we identify wave characteristics and we also study shock properties. Finally we perform a dispersion analysis and discuss the possible origin of mirror mode structures using curves of growth for different regimes of beta and proton temperature anisotropies. We study the effects that a small component of He in the plasma can have on mirror mode growth.

  3. Laboratory study of the wind structure over surface waves

    NASA Astrophysics Data System (ADS)

    Buckley, Marc; Veron, Fabrice

    2011-11-01

    Airflow dynamics above waves strongly influence exchanges of heat, momentum and mass between the Ocean and the Atmosphere. We present experimental results on the detailed structure of the airflow above waves. The experiments took place at University of Delaware's large (42m long, 1m wide, and 1.25m high) wind-wave facility where a variety of winds, wave ages and steepnesses were generated by a wind-tunnel and a mechanical wave generator. Airflow properties within and above the viscous sublayer were obtained using PIV, while wave profiles and spectra were measured by laser-induced fluorescence. We intermittently observe a separation of the viscous sublayer past the wave crest in certain wind-wave conditions. Despite the intermittent aspect of this sheltering effect, when averaged over all wave phases, our results suggest that there is a substantial along-wave variability of the surface viscous tangential stress, which in turn may affect wave growth and the air-water momentum balance.

  4. Structure and Composition of the Neutral Upper Atmosphere of Mars from the MAVEN NGIMS Investigation

    NASA Astrophysics Data System (ADS)

    Mahaffy, P. R.; Benna, M.; Yelle, R. V.; Stone, S. W.; Elrod, M. K.; Fox, J. L.

    2015-12-01

    The Neutral Gas and Ion Mass Spectrometer (NGIMS) on the MAVEN mission is designed to characterize the state of the upper atmosphere and its response to perturbations from the sun and from lower atmosphere. These measurements complement other instruments on the MAVEN spacecraft and support the MAVEN science goal [Jakosky et al., 2015] of understanding atmospheric escape and over the course of martian history. We report NGIMS measurements of the neutral composition of multiple atomic and molecular species over hundreds of orbits since the science phase of this mission began late in 2014. Ion measurements from NGIMS are reported separately in other contributions to this session. The wide dynamic range, the high temporal resolution, and the use of two different ion source configurations of the NGIMS instrument [Mahaffy et al., 2014] allows neutral density structure and its variability to be characterized in detail. Large amplitude wave structure is observed on the lowest altitude portion of many orbits that dissipates at higher altitudes. Although this structure puts scatter in the retrieval of scale height temperatures these are nevertheless robustly secured by averaging over several orbits. The variability of the upper atmosphere temperature with latitude and local solar time is reported. The deep dip campaign approach to the homopause allows the mixing ratio of the major gases in the lower atmosphere to be measured. We compare these mixing ratios with those reported by the Sample Analysis at Mars investigation and previous Viking measurements. Jakosky, B. M., et al. (2015), The Mars Atmosphere and Volatile Evolution (MAVEN) Mission, Space Sci Rev, 21. Mahaffy, P. R., et al. (2014), The Neutral Gas and Ion Mass Spectrometer on the Mars Atmosphere and Volatile Evolution Mission, Space Sci Rev, 185, DOI: 10.1007/s11214-11014-10091-11211.

  5. Relationships between adaptive and neutral genetic diversity and ecological structure and functioning: a meta-analysis

    PubMed Central

    Whitlock, Raj

    2014-01-01

    Understanding the effects of intraspecific genetic diversity on the structure and functioning of ecological communities is a fundamentally important part of evolutionary ecology and may also have conservation relevance in identifying the situations in which genetic diversity coincides with species-level diversity.Early studies within this field documented positive relationships between genetic diversity and ecological structure, but recent studies have challenged these findings. Conceptual synthesis has been hampered because studies have used different measures of intraspecific variation (phenotypically adaptive vs. neutral) and have considered different measures of ecological structure in different ecological and spatial contexts. The aim of this study is to strengthen conceptual understanding by providing an empirical synthesis quantifying the relationship between genetic diversity and ecological structure.Here, I present a meta-analysis of the relationship between genetic diversity within plant populations and the structure and functioning of associated ecological communities (including 423 effect sizes from 70 studies). I used Bayesian meta-analyses to examine (i) the strength and direction of this relationship, (ii) the extent to which phenotypically adaptive and neutral (molecular) measures of diversity differ in their association with ecological structure and (iii) variation in outcomes among different measures of ecological structure and in different ecological contexts.Effect sizes measuring the relationship between adaptive diversity (genotypic richness) and both community- and ecosystem-level ecological responses were small, but significantly positive. These associations were supported by genetic effects on species richness and productivity, respectively.There was no overall association between neutral genetic diversity and measures of ecological structure, but a positive correlation was observed under a limited set of demographic conditions. These

  6. Inhibitory and neutral antibodies to Plasmodium falciparum MSP119 form ring structures with their antigen.

    PubMed

    Dekker, Carien; Uthaipibull, Chairat; Calder, Lesley J; Lock, Matthew; Grainger, Munira; Morgan, William D; Dodson, Guy G; Holder, Anthony A

    2004-09-01

    Blood-stage malaria vaccine candidates include surface proteins of the merozoite. Antibodies to these proteins may either block essential steps during invasion or render the merozoite susceptible to phagocytosis or complement-mediated degradation. Structural information on merozoite surface proteins complexed to antibodies provides crucial information for knowledge-based vaccine design. The major merozoite surface protein MSP1 is an abundant surface molecule in Plasmodium falciparum. Only a subset of antibodies against MSP119 inhibits invasion (inhibitory antibodies), whereas other antibodies binding to MSP119 have no effect on invasion (neutral antibodies). Here we report on the complex of MSP119 with both inhibitory monoclonal antibody 12.10 and neutral monoclonal antibody 2F10. The complexes were established using both whole IgG's and Fab fragments, and analysed by dynamic light scattering, electron microscopy and analytical ultra centrifugation. Specific ring structures were formed in the ternary complex with the two antibodies, providing direct evidence of non-overlapping epitopes on MSP119. Mutational studies also indicated that the epitopes of the inhibitory and neutral antibodies are spatially remote. PMID:15279960

  7. Structure of HCMV glycoprotein B in the postfusion conformation bound to a neutralizing human antibody

    PubMed Central

    Chandramouli, Sumana; Ciferri, Claudio; Nikitin, Pavel A.; Caló, Stefano; Gerrein, Rachel; Balabanis, Kara; Monroe, James; Hebner, Christy; Lilja, Anders E.; Settembre, Ethan C.; Carfi, Andrea

    2015-01-01

    Human cytomegalovirus (HCMV) poses a significant threat to immunocompromised individuals and neonates infected in utero. Glycoprotein B (gB), the herpesvirus fusion protein, is a target for neutralizing antibodies and a vaccine candidate due to its indispensable role in infection. Here we show the crystal structure of the HCMV gB ectodomain bound to the Fab fragment of 1G2, a neutralizing human monoclonal antibody isolated from a seropositive subject. The gB/1G2 interaction is dominated by aromatic residues in the 1G2 heavy chain CDR3 protruding into a hydrophobic cleft in the gB antigenic domain 5 (AD-5). Structural analysis and comparison with HSV gB suggest the location of additional neutralizing antibody binding sites on HCMV gB. Finally, immunoprecipitation experiments reveal that 1G2 can bind to HCMV virion gB suggesting that its epitope is exposed and accessible on the virus surface. Our data will support the development of vaccines and therapeutic antibodies against HCMV infection. PMID:26365435

  8. Predicting community structure in snakes on Eastern Nearctic islands using ecological neutral theory and phylogenetic methods.

    PubMed

    Burbrink, Frank T; McKelvy, Alexander D; Pyron, R Alexander; Myers, Edward A

    2015-11-22

    Predicting species presence and richness on islands is important for understanding the origins of communities and how likely it is that species will disperse and resist extinction. The equilibrium theory of island biogeography (ETIB) and, as a simple model of sampling abundances, the unified neutral theory of biodiversity (UNTB), predict that in situations where mainland to island migration is high, species-abundance relationships explain the presence of taxa on islands. Thus, more abundant mainland species should have a higher probability of occurring on adjacent islands. In contrast to UNTB, if certain groups have traits that permit them to disperse to islands better than other taxa, then phylogeny may be more predictive of which taxa will occur on islands. Taking surveys of 54 island snake communities in the Eastern Nearctic along with mainland communities that have abundance data for each species, we use phylogenetic assembly methods and UNTB estimates to predict island communities. Species richness is predicted by island area, whereas turnover from the mainland to island communities is random with respect to phylogeny. Community structure appears to be ecologically neutral and abundance on the mainland is the best predictor of presence on islands. With regard to young and proximate islands, where allopatric or cladogenetic speciation is not a factor, we find that simple neutral models following UNTB and ETIB predict the structure of island communities. PMID:26609083

  9. Structures and vibrations of neutral and cationic 3- and 4-aminophenol

    NASA Astrophysics Data System (ADS)

    Unterberg, C.; Gerlach, A.; Jansen, A.; Gerhards, M.

    2004-10-01

    A combined experimental and theoretical study on the structures and vibrations of 3- and 4-aminophenol in their neutral and ionic ground states is presented. The vibrations of the two possible isomers of 3-aminophenol and the one isomer of 4-aminophenol are investigated by mass analyzed threshold ionization (MATI) spectroscopy in the ionic ground state and by infrared resonant 2-photon ionization (IR/R2PI) spectroscopy in the neutral ground state. The experimentally observed vibrational frequencies of all isomers are in excellent agreement with the calculated values obtained by density functional theory (DFT) and at the complete active space self-consistent field (CASSCF) level of theory. The calculations support the assignment of different isomers. Furthermore, the experimentally observed ionization potentials are well predicted by CASMP2//CASSCF calculations.

  10. THREE-DIMENSIONAL STRUCTURE OF SOLAR WIND TURBULENCE

    SciTech Connect

    Chen, C. H. K.; Bale, S. D.; Mallet, A.; Schekochihin, A. A.; Horbury, T. S.; Wicks, R. T.

    2012-10-20

    We present a measurement of the scale-dependent, three-dimensional structure of the magnetic field fluctuations in inertial range solar wind turbulence with respect to a local, physically motivated coordinate system. The Alfvenic fluctuations are three-dimensionally anisotropic, with the sense of this anisotropy varying from large to small scales. At the outer scale, the magnetic field correlations are longest in the local fluctuation direction, consistent with Alfven waves. At the proton gyroscale, they are longest along the local mean field direction and shortest in the direction perpendicular to the local mean field and the local field fluctuation. The compressive fluctuations are highly elongated along the local mean field direction, although axially symmetric perpendicular to it. Their large anisotropy may explain why they are not heavily damped in the solar wind.

  11. Structural Analysis and Design of the Composite Wind Turbine Blade

    NASA Astrophysics Data System (ADS)

    Wu, Wen-Hsiang; Young, Wen-Bin

    2012-06-01

    The wind turbine blade sustains various kinds of loadings during the operation and parking state. Due to the increasing size of the wind turbine blade, it is important to arrange the composite materials in a sufficient way to reach the optimal utilization of the material strength. Most of the composite blades are made of glass fibers composites while carbon fibers are also employed in recent years. Composite materials have the advantages of high specific strength and stress. This study develops a GUI interface to construct the blade model for the stress analysis using ANSYS. With the aid of visualization interface, the geometric model of the blade can be constructed by only a few data inputs. Based on the numerical stress analysis of the turbine blade, a simple iterative method was proposed to design the structure of the composite blade.

  12. The extended interacting wind structure of Eta Carinae

    NASA Astrophysics Data System (ADS)

    Gull, T. R.; Nielsen, K. E.; Corcoran, M. F.; Madura, T. I.; Owocki, S. P.; Russell, C. M. P.; Hillier, D. J.; Hamaguchi, K.; Kober, G. V.; Weis, K.; Stahl, O.; Okazaki, A. T.

    2009-07-01

    The highly eccentric binary system, η Car, provides clues to the transition of massive stars from hydrogen-burning via the CNO cycle to a helium-burning evolutionary state. The fast-moving wind of η Car B creates a cavity in η Car A's slower, but more massive, stellar wind, providing an in situ probe. The Hubble Space Telescope/Space Telescope Imaging Spectrograph (HST/STIS), with its high spatial and spectral resolutions, is well matched to follow temporal spatial and velocity variations of multiple wind features. We use observations obtained across 1998-2004 to produce a rudimentary three-dimensional model of the wind interaction in the η Car system. Broad (+/-500 km s-1) [FeII] emission line structures extend 0.7arcsec (~1600 au) from the stellar core. In contrast, [FeIII], [ArIII], [NeIII] and [SIII] lines extend only 0.3arcsec (700 au) from NE to SW and are blue shifted from -500 to +200 km s-1. All observed spectral features vary with the 5.54-year orbital period. The highly ionized, forbidden emission disappears during the low state, associated with periastron passage. The high-ionization emission originates in the outer wind interaction region that is directly excited by the far-ultraviolet radiation from η Car B. The HST/STIS spectra reveal a time-varying, distorted paraboloidal structure, caused by the interaction of the massive stellar winds. The model and observations are consistent with the orbital plane aligned with the skirt of the Homunculus. However, the axis of the distorted paraboloid, relative to the major axis of the binary orbit, is shifted in a prograde rotation along the plane, which projected on the sky is from NE to NW. Based on observations made with the National Aeronautics and Space Agency/European Space Agency (NASA/ESA) HST. Support for Programme numbers 7302, 8036, 8483, 8619, 9083, 9337, 9420, 9973, 10957 and 11273 was provided by NASA directly to the Space Telescope Imaging Spectrograph Science Team and through grants from the

  13. Influence of spin-orbit effects on structures and dielectric properties of neutral lead clusters

    SciTech Connect

    Götz, D. A. Shayeghi, A.; Schäfer, R.; Johnston, R. L.; Schwerdtfeger, P.

    2014-04-28

    Combining molecular beam electric deflection experiments and global optimization techniques has proven to be a powerful tool for resolving equilibrium structures of neutral metal and semiconductor clusters. Herein, we present electric molecular beam deflection experiments on Pb{sub N} (N = 7–18) clusters. Promising structures are generated using the unbiased Birmingham Cluster Genetic Algorithm approach based on density functional theory. The structures are further relaxed within the framework of two-component density functional theory taking scalar relativistic and spin orbit effects into account. Quantum chemical results are used to model electric molecular beam deflection profiles based on molecular dynamics calculations. Comparison of measured and simulated beam profiles allows the assignment of equilibrium structures for the most cluster sizes in the examined range for the first time. Neutral lead clusters adopt mainly spherical geometries and resemble the structures of lead cluster cations apart from Pb{sub 10}. Their growth pattern deviates strongly from the one observed for tin and germanium clusters.

  14. Relationship of the quaternary structure of human secretory IgA to neutralization of influenza virus

    PubMed Central

    Suzuki, Tadaki; Kawaguchi, Akira; Ainai, Akira; Tamura, Shin-ichi; Ito, Ryo; Multihartina, Pretty; Setiawaty, Vivi; Pangesti, Krisna Nur Andriana; Odagiri, Takato; Tashiro, Masato; Hasegawa, Hideki

    2015-01-01

    Secretory IgA (S-IgA) antibodies, the major contributors to humoral mucosal immunity to influenza virus infection, are polymeric Igs present in many external secretions. In the present study, the quaternary structures of human S-IgA induced in nasal mucosa after administration of intranasal inactivated influenza vaccines were characterized in relation to neutralization potency against influenza A viruses. Human nasal IgA antibodies have been shown to contain at least five quaternary structures. Direct and real-time visualization of S-IgA using high-speed atomic force microscopy (AFM) demonstrated that trimeric and tetrameric S-IgA had six and eight antigen-binding sites, respectively, and that these structures exhibited large-scale asynchronous conformational changes while capturing influenza HA antigens in solution. Furthermore, trimeric, tetrameric, and larger polymeric structures, which are minor fractions in human nasal IgA, displayed increased neutralizing potency against influenza A viruses compared with dimeric S-IgA, suggesting that the larger polymeric than dimeric forms of S-IgA play some important roles in protection against influenza A virus infection in the human upper respiratory tract. PMID:26056267

  15. Quantification of the relative roles of niche and neutral processes in structuring gastrointestinal microbiomes

    PubMed Central

    Jeraldo, Patricio; Sipos, Maksim; Chia, Nicholas; Brulc, Jennifer M.; Dhillon, A. Singh; Konkel, Michael E.; Larson, Charles L.; Nelson, Karen E.; Qu, Ani; Schook, Lawrence B.; Yang, Fang; White, Bryan A.; Goldenfeld, Nigel

    2012-01-01

    The theoretical description of the forces that shape ecological communities focuses around two classes of models. In niche theory, deterministic interactions between species, individuals, and the environment are considered the dominant factor, whereas in neutral theory, stochastic forces, such as demographic noise, speciation, and immigration, are dominant. Species abundance distributions predicted by the two classes of theory are difficult to distinguish empirically, making it problematic to deduce ecological dynamics from typical measures of diversity and community structure. Here, we show that the fusion of species abundance data with genome-derived measures of evolutionary distance can provide a clear indication of ecological dynamics, capable of quantifying the relative roles played by niche and neutral forces. We apply this technique to six gastrointestinal microbiomes drawn from three different domesticated vertebrates, using high-resolution surveys of microbial species abundance obtained from carefully curated deep 16S rRNA hypervariable tag sequencing data. Although the species abundance patterns are seemingly well fit by the neutral theory of metacommunity assembly, we show that this theory cannot account for the evolutionary patterns in the genomic data; moreover, our analyses strongly suggest that these microbiomes have, in fact, been assembled through processes that involve a significant nonneutral (niche) contribution. Our results demonstrate that high-resolution genomics can remove the ambiguities of process inference inherent in classic ecological measures and permits quantification of the forces shaping complex microbial communities. PMID:22615407

  16. Synthesis, molecular structure, and properties of a neutral Schiff base phenolic complex of magnesium

    SciTech Connect

    Polyakov, V.R.; Sharma, V.; Crankshaw, C.L.; Piwnica-Worms, D.

    1998-09-07

    Multidrug resistance (MDR) in cancer mediated by the MDR1 P-glycoprotein (Pgp), a 140--180 kDa plasma membrane protein, renders chemotherapeutic treatment ineffective by pumping a variety of natural product cytotoxic agents and xenobiotic compounds out of cancer cells. Pgp has been a major target for synthesis and development of both therapeutic antagonists that block its transport function and diagnostic radiopharmaceuticals that are transported by the protein for use in functional imaging of Pgp transport activity in tumors in vivo. Most, but not all, compounds that interact with Pgp are hydrophobic and cationic at physiological pH. To further understand the Pgp targeting properties, the authors sought to directly evaluate the effect of charge of the complex on Pgp interactions. This could be done by comparing the cytotoxicity profile of a neutral complex to that of an identical, but positively charged, complex in both drug-sensitive and multidrug-resistant cancer cells. Thus, a neutral analogue of the Ga(III) and Fe(III) complexes was desired. Herein the authors describe the synthesis and structure of a novel neutral Schiff base Mg complex and evaluate its cytotoxic potency in human drug-sensitive KB-3-1 and multi-drug-resistant KB-8-5 tumor cells.

  17. Remote Structural Health Monitoring and Advanced Prognostics of Wind Turbines

    SciTech Connect

    Douglas Brown; Bernard Laskowski

    2012-05-29

    The prospect of substantial investment in wind energy generation represents a significant capital investment strategy. In order to maximize the life-cycle of wind turbines, associated rotors, gears, and structural towers, a capability to detect and predict (prognostics) the onset of mechanical faults at a sufficiently early stage for maintenance actions to be planned would significantly reduce both maintenance and operational costs. Advancement towards this effort has been made through the development of anomaly detection, fault detection and fault diagnosis routines to identify selected fault modes of a wind turbine based on available sensor data preceding an unscheduled emergency shutdown. The anomaly detection approach employs spectral techniques to find an approximation of the data using a combination of attributes that capture the bulk of variability in the data. Fault detection and diagnosis (FDD) is performed using a neural network-based classifier trained from baseline and fault data recorded during known failure conditions. The approach has been evaluated for known baseline conditions and three selected failure modes: pitch rate failure, low oil pressure failure and a gearbox gear-tooth failure. Experimental results demonstrate the approach can distinguish between these failure modes and normal baseline behavior within a specified statistical accuracy.

  18. Scaling laws and coherent structures in the solar wind

    NASA Astrophysics Data System (ADS)

    Bruno, Roberto; D'Amicis, Raffaella; Bavassano, Bruno; Carbone, Vincenzo; Sorriso-Valvo, Luca

    2007-12-01

    The interplanetary medium is characterized by a very high Reynolds number and is pervaded by fluctuations providing information on a wide range of scales, from fractions of second up to the solar rotation period. In the past decade or so, turbulence in the solar wind has been used as a large wind tunnel to investigate scaling laws of turbulent fluctuations and multifractal models. Moreover, new interesting insights in the theory of turbulence have been derived from the point of view which considers a turbulent flow as a complex system, a sort of benchmark for the theory of dynamical systems. Important finding like the lack of a strict self-similarity of the fluctuations with the consequent nonapplicability of strict scale invariance, the strong anisotropy of velocity and magnetic field fluctuations, the clear lack of equipartition between magnetic and kinetic fluctuations all contributed to suggest the idea that interplanetary fluctuations could possibly be due to a mixture of propagating waves and static structures convected by the wind. In this paper we further discuss this point and bring new evidence about the fact that the presence of a background magnetic field introduces not only a symmetry breaking in interplanetary space but also organizes fluctuations about its large scale orientation.

  19. Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody

    PubMed Central

    Gu, Ying; Tang, Xuhua; Zhang, Xiao; Song, Cuiling; Zheng, Minghua; Wang, Kaihang; Zhang, Jun; Ng, Mun-Hon; Hew, Choy-Leong; Li, Shaowei; Xia, Ningshao; Sivaraman, J.

    2015-01-01

    Hepatitis E virus (HEV), a non-enveloped, positive-sense, single-stranded RNA virus, is a major cause of enteric hepatitis. Classified into the family Hepeviridae, HEV comprises four genotypes (genotypes 1-4), which belong to a single serotype. We describe a monoclonal antibody (mAb), 8G12, which equally recognizes all four genotypes of HEV, with ∼2.53–3.45 nM binding affinity. The mAb 8G12 has a protective, neutralizing capacity, which can significantly block virus infection in host cells. Animal studies with genotypes 1, 3 and 4 confirmed the cross-genotype neutralizing capacity of 8G12 and its effective prevention of hepatitis E disease. The complex crystal structures of 8G12 with the HEV E2s domain (the most protruded region of the virus capsid) of the abundant genotypes 1 and 4 were determined at 4.0 and 2.3 Å resolution, respectively. These structures revealed that 8G12 recognizes both genotypes through the epitopes in the E2s dimerization region. Structure-based mutagenesis and cell-model assays with virus-like particles identified several conserved residues (Glu549, Lys554 and Gly591) that are essential for 8G12 neutralization. Moreover, the epitope of 8G12 is identified as a key epitope involved in virus-host interactions. These findings will help develop a common strategy for the prevention of the most abundant form of HEV infection. PMID:25793314

  20. Nonlinear development of shocklike structure in the solar wind.

    PubMed

    Lee, E; Parks, G K; Wilber, M; Lin, N

    2009-07-17

    We report first in situ multispacecraft observations of nonlinear steepening of compressional pulses in the solar wind upstream of Earth's bow shock. The magnetic field of a compressional pulse formed at the upstream edge of density holes is shown to suddenly break and steepen into a shocklike structure. During the early phase of development thermalization of ions is insignificant. Substantial thermalization of ions occurs as gyrating ions are observed at the steepened edge. These observations indicate that the mechanisms causing the dissipation of magnetic fields (currents) and ions are different in the early phase of shock development. PMID:19659262

  1. The Origins of Magnetic Structure in the Corona and Wind

    NASA Technical Reports Server (NTRS)

    Antiochos, Spiro K.

    2010-01-01

    One of the most important and most puzzling features of the coronal magnetic field is that it appears to have smooth magnetic structure with little evidence for non-potentiality except at two special locations: photospheric polarity inversions lines. (non-potentiality observed as a filament channel) and coronal hole boundaries, (observed as the slow solar wind). This characteristic feature of the closed-field corona is highly unexpected given that its magnetic field is continuously tangled by photospheric motions. Although reconnection can eliminate some of the injected structure, it cannot destroy the helicity, which should build up to produce observable complexity. I propose that an inverse cascade process transports the injected helicity from the interior of closed flux regions to their boundaries inversion lines and coronal holes, creating both filament channels and the slow wind. We describe how the helicity is injected and transported and calculate the relevant rates. I argue that one process, helicity transport, can explain both the observed lack and presence of structure in the coronal magnetic field. This work has been supported by the NASA HTP, SR&T, and LWS programs.

  2. The Photoevaporation of a Neutral Structure by an EUV+FUV Radiation Field

    NASA Astrophysics Data System (ADS)

    Lora, Veronica; Vasconcelos, M. J.; Raga, A. C.; Cerqueira, A. H.; Esquivel, A.

    The expansion of an HII region into a surrounding inhomogeneous molecular cloud, leads to the formation of elongated "elephant trunk" structures. The EUV photo-ionising radiation and FUV dissociating radiation from newly born stars photo-evaporate their parental neutral cloud, leading to the formation of dense clumps in the tips of elephant trunks, that could in principle eventually form stars. We study th effects of including a photo-dissociating FUV flux in models of fragmentation of a photo-evaporating, self-gravitating molecular cloud.

  3. Structure of adeno-associated virus-2 in complex with neutralizing monoclonal antibody A20

    SciTech Connect

    McCraw, Dustin M.; O'Donnell, Jason K.; Taylor, Kenneth A.; Stagg, Scott M.; Chapman, Michael S.

    2012-09-15

    The use of adeno-associated virus (AAV) as a gene therapy vector is limited by the host neutralizing immune response. The cryo-electron microscopy (EM) structure at 8.5 A resolution is determined for a complex of AAV-2 with the Fab' fragment of monoclonal antibody (MAb) A20, the most extensively characterized AAV MAb. The binding footprint is determined through fitting the cryo-EM reconstruction with a homology model following sequencing of the variable domain, and provides a structural basis for integrating diverse prior epitope mappings. The footprint extends from the previously implicated plateau to the side of the spike, and into the conserved canyon, covering a larger area than anticipated. Comparison with structures of binding and non-binding serotypes indicates that recognition depends on a combination of subtle serotype-specific features. Separation of the neutralizing epitope from the heparan sulfate cell attachment site encourages attempts to develop immune-resistant vectors that can still bind to target cells.

  4. The Response of the Ionospheric Cusp to the Solar Wind Through Two Perspectives: Low Energy Charged Particle In-Situ Measurements and Low-Energy Neutral Atom Imaging

    NASA Technical Reports Server (NTRS)

    Coffey, V. N.; Moore, T. E.; Chandler, M. O.; Giles, B. L.; Craven, P. D.; Rose, M. Franklin (Technical Monitor)

    2000-01-01

    The Imager for Magnetopause-to-Aurora Global Exploration (IMAGE) mission provides a new perspective on the study of the response of the magnetosphere/ionosphere system to changing solar wind conditions, particularly the variability of ion outflow. Learning to interpret this new type of data becomes an essential step in the process of melding these results with the wealth of in-situ charged particle observations obtained over the past 25 years. In order to understand how the in-situ data correspond to and contrast with IMAGE results we will perform a conjunctive study of event data from two instruments to shed light on the coupling of the solar wind and ionosphere from these different perspectives. We will use the Low Energy Neutral Atom instrument (LENA) which images energetic neutral atom emissions from upward flowing ionospheric ions and the Thermal Ion Dynamics Instrument (TIDE) on the Polar satellite which measures in-situ ion outflow from 0.3-300 eV. Our primary goal will be to understand how comparing the imaging and in-situ perspectives can aid in the analysis of both data sets.

  5. Structural Insights into the Neutralization Properties of the Fully Human, Anti-interferon Monoclonal Antibody Sifalimumab.

    PubMed

    Oganesyan, Vaheh; Peng, Li; Woods, Robert M; Wu, Herren; Dall'Acqua, William F

    2015-06-12

    We report the three-dimensional structure of human interferon α-2A (IFN-α2A) bound to the Fab fragment of a therapeutic monoclonal antibody (sifalimumab; IgG1/κ). The structure of the corresponding complex was solved at a resolution of 3.0 Å using molecular replacement and constitutes the first reported structure of a human type I IFN bound to a therapeutic antibody. This study revealed the major contribution made by the first complementarity-determining region in each of sifalimumab light and heavy chains. These data also provided the molecular basis for sifalimumab mechanism of action. We propose that its interferon-neutralizing properties are the result of direct competition for IFN-α2A binding to the IFN receptor subunit 1 (IFNAR1) and do not involve inhibiting IFN-α2A binding to the IFN receptor subunit 2 (IFNAR2). PMID:25925951

  6. The global structure of hot star winds: Constraints from spectropolarimetry

    NASA Astrophysics Data System (ADS)

    Eversberg, Thomas

    2000-11-01

    Chapter 1. We present time-series of ultra-high S/N, high resolution spectra of the He II λ 4686 Å emission line in the O4I(n)f supergiant ζ Puppis, the brightest early-type O-star in the sky. These reveal stochastic, variable substructures in the line, which tend to move away from the line-center with time. Similar scaled-up features are well established in the strong winds of Wolf-Rayet stars (the presumed descendants of O stars), where they are explained by outward moving inhomogeneities (e.g., blobs, clumps, shocks) in the winds. If all hot-star winds are clumped like that of ζ Pup, as is plausible, then mass-low rates based on recombination-line intensities will have to be revised downwards. Using a standard `β' velocity law we deduce a value of β = 1.0-1.2 to account for the kinematics of these structures in the wind of ζ Pup. In addition to the small-scale stochastic variations we also find a slow systematic variation of the mean central absorption reversal. Chapter 2. We introduce a new polarimeter unit which, mounted at the Cassegrain focus of any telescope and fiber-connected to a fixed CCD spectrograph, is able to measure all Stokes parameters I, Q, U and V across spectral lines of bright stellar targets and other point sources in a quasi-simultaneous manner. Applying standard reduction techniques for linearly and circularly polarized light we are able to obtain photon-noise limited line polarization. We briefly outline the technical design of the polarimeter unit and the linear algebraic Mueller calculus for obtaining polarization parameters of any point source. In addition, practical limitations of the optical elements are outlined. We present first results obtained with our spectropolarimeter for four bright, hot-star targets: We confirm previous results for Hα in the bright Be star γ Cas and find linear depolarization features across the emission line complex C III/C IV (λ 5696/λ 5808 Å) of the WR+O binary γ2 Vel. We also find circular

  7. Electrodynamics, wind and temperature

    NASA Technical Reports Server (NTRS)

    Schmidlin, F. J.

    1988-01-01

    This RTOP provides for correlative meteorological wind and temperature measurements with atmospheric electrodynamic measurements. Meteorological rocketsondes were launched as part of a number of electrodynamic investigations in Alaska, Norway, Peru, Sweden, and at the Wallops Flight Facility, Wallops Island, Virginia. Measurements obtained as part of the MAC/Epsilon campaign during October 1987 from Andoya, Norway, were in conjunction with electric field, ion mobility, conductivity, and energy deposition studies. The measurements obtained between 30 and 90 km are to evaluate and correlate changes in the atmospheric electrical structure caused by the neutral wind and temperature, or changes in the neutral atmosphere resulting from electrical anomalies.

  8. Inherent Variability in Short-time Wind Turbine Statistics from Turbulence Structure in the Atmospheric Surface Layer

    NASA Astrophysics Data System (ADS)

    Lavely, Adam; Vijayakumar, Ganesh; Brasseur, James; Paterson, Eric; Kinzel, Michael

    2011-11-01

    Using large-eddy simulation (LES) of the neutral and moderately convective atmospheric boundary layers (NBL, MCBL), we analyze the impact of coherent turbulence structure of the atmospheric surface layer on the short-time statistics that are commonly collected from wind turbines. The incoming winds are conditionally sampled with a filtering and thresholding algorithm into high/low horizontal and vertical velocity fluctuation coherent events. The time scales of these events are ~5 - 20 blade rotations and are roughly twice as long in the MCBL as the NBL. Horizontal velocity events are associated with greater variability in rotor power, lift and blade-bending moment than vertical velocity events. The variability in the industry standard 10 minute average for rotor power, sectional lift and wind velocity had a standard deviation of ~ 5% relative to the ``infinite time'' statistics for the NBL and ~10% for the MCBL. We conclude that turbulence structure associated with atmospheric stability state contributes considerable, quantifiable, variability to wind turbine statistics. Supported by NSF and DOE.

  9. Effects of magnetospheric electric fields and neutral winds on the low-middle latitude ionosphere during the March 20-21, 1990, Storm

    SciTech Connect

    Buonsanto, M.J.; Foster, J.C.

    1993-11-01

    During the geomagnetic storm of March 20-21, 1990, substorm activity is clearly evident in magnetometer data collected during the night at the middle- and low-latitude stations Fredericksburg (38.2{degrees}N, 282.6{degrees}E) and San Juan (18.1{degrees}N, 293.8{degrees}E). At the same time, incoherent scatter radars at Millstone Hill (42.6{degrees}N, 288.5{degrees}E) and Arecibo (18.3{degrees}N, 293.25{degrees}E) observed ionospheric storm effects, which included the penetration of magnetospheric electric fields and disturbance neutral winds to the latitude of Arecibo. The eastward electric fields associated with the substorm disturbances result in increases in the F2 peak height (hmF2) at Arecibo. Decreases in hmF2 follow as a result of increased downward diffusion and/or the effects of an ion drag induced poleward wind. During the intervals between the electric field penetration events, equatorward surges in the neutral wind result in westward electric fields by the disturbance dynamo mechanism. At these times the horizontal ionization drifts are not as strong as the neutral winds, apparently because of a partial shorting out of the dynamo electric fields as a result of some E region conductivity. The anticorrelation between the components of ion drift parallel (V{sub {parallel}}) and perpendicular to the magnetic field in the northward direction (V{sub {perpendicular}}N) results in approximately horizontal (constant altitude) ion drift motion throughout the interval. Calculations of spatial gradients in the electron density and in the components of the ion velocity are carried out using the multi-directional incoherent scatter observations at Arecibo. The results show that the variations in electron density during the disturbed interval follow closely the motion term in the F2 region continuity equation, with both advection of spatial gradients and divergence of the ion flow important at times. 28 refs., 8 figs.

  10. Wind structure and small-scale wind variability in the stratosphere and mesosphere during the November 1980 Energy Budget Campaign

    NASA Technical Reports Server (NTRS)

    Schmidlin, F. J.; Carlson, M.; Rees, D.; Offermann, D.; Philbrick, C. R.; Widdel, H. U.

    1982-01-01

    Rocket observations made from two sites in northern Scandinavia between November 6 and December 1, 1980, as part of the Energy Budget Campaign are discussed. It was found that significant vertical and temporal changes in the wind structure were present and that they coincided with different geomagnetic conditions, that is, quiet and enhanced. Before November 16, the meridional wind component above 60 km was found to be positive (southerly), whereas the magnitude of the zonal wind component increased with altitude. After November 16 the meridional component became negative (northerly), and the magnitude of the zonal wind component was observed to decrease with altitude. Time sections of the perturbations of the zonal wind reveal the presence of vertically propagating waves, suggesting gravity wave activity. The waves are found to increase in wavelength from 3-4 km near 40 km to more than 12 km near 80 km. The observational techniques made use of chaff foil, chemical trails, inflatable spheres, and parachutes.

  11. Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase

    PubMed Central

    McGowan, Sheena; Porter, Corrine J.; Lowther, Jonathan; Stack, Colin M.; Golding, Sarah J.; Skinner-Adams, Tina S.; Trenholme, Katharine R.; Teuscher, Franka; Donnelly, Sheila M.; Grembecka, Jolanta; Mucha, Artur; Kafarski, Pawel; DeGori, Ross; Buckle, Ashley M.; Gardiner, Donald L.; Whisstock, James C.; Dalton, John P.

    2009-01-01

    Plasmodium falciparum parasites are responsible for the major global disease malaria, which results in >2 million deaths each year. With the rise of drug-resistant malarial parasites, novel drug targets and lead compounds are urgently required for the development of new therapeutic strategies. Here, we address this important problem by targeting the malarial neutral aminopeptidases that are involved in the terminal stages of hemoglobin digestion and essential for the provision of amino acids used for parasite growth and development within the erythrocyte. We characterize the structure and substrate specificity of one such aminopeptidase, PfA-M1, a validated drug target. The X-ray crystal structure of PfA-M1 alone and in complex with the generic inhibitor, bestatin, and a phosphinate dipeptide analogue with potent in vitro and in vivo antimalarial activity, hPheP[CH2]Phe, reveals features within the protease active site that are critical to its function as an aminopeptidase and can be exploited for drug development. These results set the groundwork for the development of antimalarial therapeutics that target the neutral aminopeptidases of the parasite. PMID:19196988

  12. Microburst wind structure and evaluation of Doppler radar for airport wind shear detection

    NASA Technical Reports Server (NTRS)

    Wilson, J. W.; Roberts, R. D.; Kessinger, C.; Mccarthy, J.

    1984-01-01

    The horizontal and vertical structure of airflow within microbursts has been determined using Doppler weather radar data from the Joint Airport Weather Studies (JAWS) Project. It is shown that the downdraft typically associated with microbursts is about 1 km wide and begins to spread horizontally at a height below 1 km. The median time from initial divergence at the surface to maximum differential wind velocity across the microburst is five minutes. The height of maximum differential velocity is about 75 m, and the median velocity differential is 22 m/s over an average distance of 3.1 km. The outflow of the air is asymmetric, averaging twice as strong along the maximum axis compared to the mininum axis. Some technical requirements for a radar system to detect microbursts and to provide aircraft with early warnings of the onset of windshear are identified.

  13. Structural analysis of wind turbine rotors for NSF-NASA Mod-0 wind power system

    NASA Technical Reports Server (NTRS)

    Spera, D. A.

    1976-01-01

    Preliminary estimates are presented of vibratory loads and stresses in hingeless and teetering rotors for the proposed NSF-NASA Mod-0 wind power system. Preliminary blade design utilizes a tapered tubular aluminum spar which supports nonstructural aluminum ribs and skin and is joined to the rotor hub by a steel shank tube. Stresses in the shank of the blade are calculated for static, rated, and overload operating conditions. Blade vibrations were limited to the fundamental flapping modes, which were elastic cantilever bending for hingeless rotor blades and rigid-body rotation for teetering rotor blades. The MOSTAB-C computer code was used to calculate aerodynamic and mechanical loads. The teetering rotor has substantial advantages over the hingeless rotor with respect to shank stresses, fatigue life, and tower loading. The hingeless rotor analyzed does not appear to be structurally stable during overloads.

  14. Advanced Fluid--Structure Interaction Techniques in Application to Horizontal and Vertical Axis Wind Turbines

    NASA Astrophysics Data System (ADS)

    Korobenko, Artem

    During the last several decades engineers and scientists put significant effort into developing reliable and efficient wind turbines. As a wind power production demands grow, the wind energy research and development need to be enhanced with high-precision methods and tools. These include time-dependent, full-scale, complex-geometry advanced computational simulations at large-scale. Those, computational analysis of wind turbines, including fluid-structure interaction simulations (FSI) at full scale is important for accurate and reliable modeling, as well as blade failure prediction and design optimization. In current dissertation the FSI framework is applied to most challenging class of problems, such as large scale horizontal axis wind turbines and vertical axis wind turbines. The governing equations for aerodynamics and structural mechanics together with coupled formulation are explained in details. The simulations are performed for different wind turbine designs, operational conditions and validated against field-test and wind tunnel experimental data.

  15. Traceback of intermittent structures in the solar wind

    NASA Astrophysics Data System (ADS)

    Nakwacki, M. S.; Ruiz, M. E.; Nuevo, F. A.; Mandrini, C. H.; Dasso, S.

    The intermittent structures identified in the solar wind (SW) are a key observable to study the nature of magnetohydrodynamic (MHD) turbulence in systems with low dissipation rate; and can be characterized by computing the degree of phase correlation of the magnetic field. Such indicator is; commonly; studied near the Earth using in situ observations; while the solar wind sources remain unknown. In this work; we analise in situ observations of magnetic field intensity from the Advanced Composition Explorer (ACE) spacecraft; located near 1 AU from the Sun; and synoptic charts provided by the Wilcox Obsevatory. We complement our study computing Potential Field Source Surface (PFSS) models taking as boundary conditions synoptic maps from the Michelson Doppler Imager (MDI) onboard the Solar and Heliospheric Observatory (SOHO). We identify one intermittent period by computing the phase coherence index. For these SW observations; we attempt to find the corresponding solar source identifying a particular pattern of the coronal magnetic field at the source surface; located at 2.5 at the time the SW would have left the Sun considering its speed at 1 AU to be constant. To ascertain that this magnetic pattern plays a significant role as source of SW intermittence; more examples should be analyzed.

  16. Ion-Neutral Coupling in Solar Prominence

    NASA Technical Reports Server (NTRS)

    Gilbert, H.; DeVore, C. R.; Karpen, J.; Kucera, T.; Antiochos, S.; Kawashima, R.

    2011-01-01

    Coupling between ions and neutrals in magnetized plasmas is fundamentally important to many aspects of heliophysics, including our ionosphere, the solar chromosphere, the solar wind interaction with planetary atmospheres, and the interface between the heliosphere and the interstellar medium. Ion-neutral coupling also plays a major role in the physics of solar prominences. By combining theory, modeling, and observations we are working toward a better understanding of the structure and dynamics of partially ionized prominence plasma. Two key questions are addressed in the present work: 1) what physical mechanism(s) sets the cross-field scale of prominence threads? 2) Are ion-neutral interactions responsible for the vertical flows and structure in prominences? We present initial results from a study investigating what role ion-neutral interactions play in prominence dynamics and structure. This research was supported by NASA.

  17. An integrated structural strength analysis method for Spar type floating wind turbine

    NASA Astrophysics Data System (ADS)

    Hu, Zhi-qiang; Liu, Yi; Wang, Jin

    2016-04-01

    An integrated structural strength analysis method for a Spar type floating wind turbine is proposed in this paper, and technical issues related to turbine structure modeling and stress combination are also addressed. The NREL-5MW "Hywind" Spar type wind turbine is adopted as study object. Time-domain dynamic coupled simulations are performed by a fully-coupled aero-hydro-servo-elastic tool, FAST, on the purpose of obtaining the dynamic characteristics of the floating wind turbine, and determining parameters for design load cases of finite element calculation. Then design load cases are identified, and finite element analyses are performed for these design load cases. The structural stresses due to wave-induced loads and wind-induced loads are calculated, and then combined to assess the structural strength of the floating wind turbine. The feasibility of the proposed structural strength analysis method for floating wind turbines is then validated.

  18. Neutral-ligand complexes of bis(imino)pyridine iron: synthesis, structure, and spectroscopy.

    PubMed

    Bart, Suzanne C; Lobkovsky, Emil; Bill, Eckhard; Wieghardt, Karl; Chirik, Paul J

    2007-08-20

    A family of bis(imino)pyridine iron neutral-ligand derivatives, ((iPr)PDI)FeL(n) ((iPr)PDI = 2,6-(2,6-iPr2-C6H3N=CMe)2C6H3N), has been synthesized from the corresponding bis(dinitrogen) complex, ((iPr)PDI)Fe(N2)2. When L is a strong-field ligand such as tBuNC or a chelating alkyl diphosphine such as DEPE (DEPE = 1,2-bis(diethylphosphino)ethane), a five-coordinate, diamagnetic compound results with no spectroscopic evidence for mixing of paramagnetic states. Reducing the field strength of the neutral donor to principally sigma-type ligands such as tBuNH2 or THT (THT = tetrahydrothiophene) also yielded diamagnetic compounds. However, the 1H NMR chemical shifts of the in-plane bis(imino)pyridine hydrogens exhibit a large chemical shift dispersion indicative of temperature-independent paramagnetism (TIP) arising from mixing of an S = 1 excited state via spin-orbit coupling. Metrical data from X-ray diffraction establish bis(imino)pyridine chelate reduction for each structural type, while Mössbauer parameters and NMR spectroscopic data differentiate the spin states of the iron and identify contributions from paramagnetic excited states. PMID:17655227

  19. Structural basis of potent Zika-dengue virus antibody cross-neutralization.

    PubMed

    Barba-Spaeth, Giovanna; Dejnirattisai, Wanwisa; Rouvinski, Alexander; Vaney, Marie-Christine; Medits, Iris; Sharma, Arvind; Simon-Lorière, Etienne; Sakuntabhai, Anavaj; Cao-Lormeau, Van-Mai; Haouz, Ahmed; England, Patrick; Stiasny, Karin; Mongkolsapaya, Juthathip; Heinz, Franz X; Screaton, Gavin R; Rey, Félix A

    2016-08-01

    Zika virus is a member of the Flavivirus genus that had not been associated with severe disease in humans until the recent outbreaks, when it was linked to microcephaly in newborns in Brazil and to Guillain-Barré syndrome in adults in French Polynesia. Zika virus is related to dengue virus, and here we report that a subset of antibodies targeting a conformational epitope isolated from patients with dengue virus also potently neutralize Zika virus. The crystal structure of two of these antibodies in complex with the envelope protein of Zika virus reveals the details of a conserved epitope, which is also the site of interaction of the envelope protein dimer with the precursor membrane (prM) protein during virus maturation. Comparison of the Zika and dengue virus immunocomplexes provides a lead for rational, epitope-focused design of a universal vaccine capable of eliciting potent cross-neutralizing antibodies to protect simultaneously against both Zika and dengue virus infections. PMID:27338953

  20. The kinematics and spiral structure of the Galaxy from the neutral hydrogen

    NASA Astrophysics Data System (ADS)

    Petrovskaya, I. V.

    The kinematical and structural characteristics of the Galaxy are investigated using the whole 21-cm line profile of the neutral hydrogen emission. The concerted rotation curve and the spiral arms parameters are obtained. The Galaxy is found to have four armes with the pitch angle i = 14^circ in the region R >= 0.6R_0 and the gaseous ring when 0.4 < R / R_0 < 0.6. The Sun is between the arms. Comparing the rotation laws of the neutral and ionised gas subsystems we found the distance of the Sun to the Galactic centre R_0 = 7.5 plus or minus 1.0 kpk. The rotation velocity has a signature with the depression approximatedly 20 km/s near R = R_0. The velocity jump may be connected with giant vortices near corotation region. The parameters of the anticyclonic motion in that region are investigated. Our method of interpretation of the 21 cm profile gives the possibility to investigate z-dependance of the velocity field. To solve this problem for the inner region of the Galaxy (R

  1. An Experimental Field Dataset with Buoyant, Neutral, and Dense Gas Atmospheric Releases and Model Comparisons in Low-Wind Speed (Diffusion) Conditions

    SciTech Connect

    Veronica E. Wannberg, Gustavious Williams, Patrick Sawyer, and Richard Venedam

    2010-09-01

    Aunique field dataset from a series of low–wind speed experiments, modeling efforts using three commonly used models to replicate these releases, and statistical analysis of how well these models were able to predict the plume concentrations is presented. The experiment was designed to generate a dataset to describe the behavior of gaseous plumes under low-wind conditions and the ability of current, commonly used models to predict these movements. The dataset documents the release and transport of three gases: ammonia (buoyant), ethylene (neutral), and propylene (dense) in low–wind speed (diffusion) conditions. Release rates ranged from 1 to 20 kg h21. Ammonia and ethylene had five 5-min releases each to represent puff releases and five 20-min releases each to represent plume releases. Propylene had five 5-min puffs, six 20-min plumes, and a single 30-min plume. Thirty-two separate releases ranging from 6 to 47 min were conducted, of which only 30 releases generated useful data. The data collected included release rates, atmospheric concentrations to 100 m from the release point, and local meteorological conditions. The diagnostics included nine meteorological stations on 100-m centers and 36 photoionization detectors in a radial pattern. Three current stateof- the-practice models, Aerial locations of Hazardous Atmospheres (ALOHA), Emergency Prediction Information code (EPIcode), and Second-Order Closure Integrated Puff (SCIPUFF), were used to try to duplicate the measured field results. Low wind speeds are difficult to model, and all of the models had difficulty replicating the field measurements. However, the work does show that these models, if used correctly, are conservative (overpredict concentrations) and can be used for safety and emergency planning.

  2. Facilitating wind development: the importance of electric industry structure

    SciTech Connect

    Kirby, Brendan; Milligan, Michael

    2008-04-15

    ISOs and RTOs, with their day-ahead and real-time markets, large geographies to aggregate diverse wind resources, large loads to aggregate with wind, large generation pools that tap conventional-generator flexibility, and regional transmission planning efforts, offer the best environments for wind generation to develop. (author)

  3. Structural fatigue test results for large wind turbine blade sections

    NASA Technical Reports Server (NTRS)

    Faddoul, J. R.; Sullivan, T. L.

    1982-01-01

    In order to provide quantitative information on the operating life capabilities of wind turbine rotor blade concepts for root-end load transfer, a series of cantilever beam fatigue tests was conducted. Fatigue tests were conducted on a laminated wood blade with bonded steel studs, a low cost steel spar (utility pole) with a welded flange, a utility pole with additional root-end thickness provided by a swaged collar, fiberglass spars with both bonded and nonbonded fittings, and, finally, an aluminum blade with a bolted steel fitting (Lockheed Mod-0 blade). Photographs, data, and conclusions for each of these tests are presented. In addition, the aluminum blade test results are compared to field failure information; these results provide evidence that the cantilever beam type of fatigue test is a satisfactory method for obtaining qualitative data on blade life expectancy and for identifying structurally underdesigned areas (hot spots).

  4. ON THE APPARENT ASSOCIATIONS BETWEEN INTERSTELLAR NEUTRAL HYDROGEN STRUCTURE AND (WMAP) HIGH-FREQUENCY CONTINUUM EMISSION

    SciTech Connect

    Verschuur, Gerrit L.

    2010-03-10

    Galactic neutral hydrogen (H I) within a few hundred parsecs of the Sun contains structure with an angular distribution that is similar to small-scale structure observed by the Wilkinson Microwave Anisotropy Probe (WMAP). A total of 108 associated pairs of associated H I and WMAP features have now been cataloged using H I data mapped in 2 km s{sup -1} intervals and these pairs show a typical offset of 0.{sup 0}8. A large-scale statistical test for a direct association is carried out that casts little additional light on whether the these small offsets are merely coincidental or carry information. To pursue the issue further, the nature of several of the features within the foreground H I most closely associated with WMAP structure is examined in detail and it is shown that the cross-correlation coefficient for well-matched pairs of structures is of order unity. It is shown that free-free emission from electrons in unresolved density enhancements in interstellar space could theoretically produce high-frequency radio continuum radiation at the levels observed by WMAP and that such emission will appear nearly flat across the WMAP frequency range. Evidence for such structure in the interstellar medium already exists in the literature. Until higher angular resolution observations of the high-frequency continuum emission structure as well as the apparently associated H I structure become available, it may be difficult to rule out the possibility that some if not all the small-scale structure usually attributed to the cosmic microwave background may have a galactic origin.

  5. On the Apparent Associations Between Interstellar Neutral Hydrogen Structure and (WMAP) High-frequency Continuum Emission

    NASA Astrophysics Data System (ADS)

    Verschuur, Gerrit L.

    2010-03-01

    Galactic neutral hydrogen (H I) within a few hundred parsecs of the Sun contains structure with an angular distribution that is similar to small-scale structure observed by the Wilkinson Microwave Anisotropy Probe (WMAP). A total of 108 associated pairs of associated H I and WMAP features have now been cataloged using H I data mapped in 2 km s-1 intervals and these pairs show a typical offset of 0fdg8. A large-scale statistical test for a direct association is carried out that casts little additional light on whether the these small offsets are merely coincidental or carry information. To pursue the issue further, the nature of several of the features within the foreground H I most closely associated with WMAP structure is examined in detail and it is shown that the cross-correlation coefficient for well-matched pairs of structures is of order unity. It is shown that free-free emission from electrons in unresolved density enhancements in interstellar space could theoretically produce high-frequency radio continuum radiation at the levels observed by WMAP and that such emission will appear nearly flat across the WMAP frequency range. Evidence for such structure in the interstellar medium already exists in the literature. Until higher angular resolution observations of the high-frequency continuum emission structure as well as the apparently associated H I structure become available, it may be difficult to rule out the possibility that some if not all the small-scale structure usually attributed to the cosmic microwave background may have a galactic origin.

  6. Exploring Vertical Turbulence Structure in Neutrally and Stably Stratified Flows Using the Weather Research and Forecasting-Large-Eddy Simulation (WRF-LES) Model

    NASA Astrophysics Data System (ADS)

    Udina, Mireia; Sun, Jielun; Kosović, Branko; Soler, Maria Rosa

    2016-07-01

    Following Sun et al. (J Atmos Sci 69(1):338-351, 2012), vertical variations of turbulent mixing in stably stratified and neutral environments as functions of wind speed are investigated using the large-eddy simulation capability in the Weather Research and Forecasting model. The simulations with a surface cooling rate for the stable boundary layer (SBL) and a range of geostrophic winds for both stable and neutral boundary layers are compared with observations from the Cooperative Atmosphere-Surface Exchange Study 1999 (CASES-99). To avoid the uncertainty of the subgrid scheme, the investigation focuses on the vertical domain when the ratio between the subgrid and the resolved turbulence is small. The results qualitatively capture the observed dependence of turbulence intensity on wind speed under neutral conditions; however, its vertical variation is affected by the damping layer used in absorbing undesirable numerical waves at the top of the domain as a result of relatively large neutral turbulent eddies. The simulated SBL fails to capture the observed temperature variance with wind speed and the observed transition from the SBL to the near-neutral atmosphere with increasing wind speed, although the vertical temperature profile of the simulated SBL resembles the observed profile. The study suggests that molecular thermal conduction responsible for the thermal coupling between the surface and atmosphere cannot be parameterized through the Monin-Obukhov bulk relation for turbulent heat transfer by applying the surface radiation temperature, as is common practice when modelling air-surface interactions.

  7. More about arc-polarized structures in the solar wind

    NASA Astrophysics Data System (ADS)

    Haaland, S.; Sonnerup, B.; Paschmann, G.

    2012-05-01

    We report results from a Cluster-based study of the properties of 28 arc-polarized magnetic structures (also called rotational discontinuities) in the solar wind. These Alfvénic events were selected from the database created and analyzed by Knetter (2005) by use of criteria chosen to eliminate ambiguous cases. His studies showed that standard, four-spacecraft timing analysis in most cases lacks sufficient accuracy to identify the small normal magnetic field components expected to accompany such structures, leaving unanswered the question of their existence. Our study aims to break this impasse. By careful application of minimum variance analysis of the magnetic field (MVAB) from each individual spacecraft, we show that, in most cases, a small but significantly non-zero magnetic field component was present in the direction perpendicular to the discontinuity. In the very few cases where this component was found to be large, examination revealed that MVAB had produced an unusual and unexplained orientation of the normal vector. On the whole, MVAB shows that many verifiable rotational discontinuities (Bn ≠ 0) exist in the solar wind and that their eigenvalue ratio (EVR = intermediate/minimum variance) can be extremely large (up to EVR = 400). Each of our events comprises four individual spacecraft crossings. The events include 17 ion-polarized cases and 11 electron-polarized ones. Fifteen of the ion events have widths ranging from 9 to 21 ion inertial lengths, with two outliers at 46 and 54. The electron-polarized events are generally thicker: nine cases fall in the range 20-71 ion inertial lengths, with two outliers at 9 and 13. In agreement with theoretical predictions from a one-dimensional, ideal, Hall-MHD description (Sonnerup et al., 2010), the ion-polarized events show a small depression in field magnitude, while the electron-polarized ones tend to show a small enhancement. This effect was also predicted by Wu and Lee (2000). Judging only from the sense of

  8. Structural investigation of a neutral extracellular glucan from Lactobacillus reuteri SK24.003.

    PubMed

    Miao, Ming; Ma, Yajun; Jiang, Bo; Huang, Chao; Li, Xiaohui; Cui, Steve W; Zhang, Tao

    2014-06-15

    The structural features of a neutral extracellular glucan derived from Lactobacillus reuteri SK24.003 were investigated. Colonies of the strain SK24.003 exhibited a creamy and slimy morphological appearance on MRS solid medium and were identified as L. reuteri via 16S rDNA sequence analysis. The exopolysaccharide produced from sucrose was composed exclusively of glucose, and the weight-average molecular weight was 4.31 × 10(7)g/mol. The polysaccharide exhibited an α-(1→4) backbone with an α-(1→6) branch at every fourth residue, as deduced from both NMR and GC-MS data. The exopolysaccharide acted as a natural steel corrosion inhibitor. The results suggested that a novel α-glucan produced by L. reuteri SK24.00 could be broadly used in food and material field. PMID:24721093

  9. A comparison of mesosphere and lower thermosphere neutral winds as determined by meteor and medium-frequency radar at 70°N

    NASA Astrophysics Data System (ADS)

    Hall, C. M.; Aso, T.; Tsutsumi, M.; Nozawa, S.; Manson, A. H.; Meek, C. E.

    2005-08-01

    There has been much discussion as to the veracity of neutral wind measurements made using medium-frequency radar (MFR) employing the spaced-antenna technique. Such systems are able to operate continuously, providing information on mesosphere and lower thermosphere dynamics with typical resolutions of 3 km in altitude and 5 min in time, and thus represent a low-cost monitoring of the atmosphere. It is similarly important to be able to trust the results, and therefore we make a dedicated comparison between the Tromsø MFR (70°N, 19°E) and the newly installed and colocated Nippon/Norway Tromsø meteor radar. The agreement is particularly good between 75 and 85 km.

  10. Identification of large scale billows-like structure in the neutral Na layer over Arecibo

    NASA Astrophysics Data System (ADS)

    Sarkhel, S.; Raizada, S.; Tepley, C. A.; Gonzalez, S. A.; Mathews, J. D.

    2011-12-01

    This investigation is based on case studies of sodium (Na) concentration profiles that were obtained from Arecibo, Puerto Rico (18.4o N; 66.7o W). The data from one night reveal the presence of large scale billows-like structures in the Na layer occurring in an altitude range of 102-108 km. However, no large scale structures were observed in that altitude range on the following night. In order to explain the occurrence of these structures, Lomb-Scargle periodogram analyses were carried out. Based on these results, the role of different instability mechanisms will be discussed in light of mesospheric dynamics that can create billows-like structures. The simultaneous measurements of electron density obtained using the Arecibo Incoherent Scatter Radar will also be discussed to investigate the relation between electrons and neutrals. We also note the presence of ~1 hour period oscillations that may be related to continuous quasi-periodic processes of the same period noted at higher altitudes.

  11. The Energy-Dependent Position of the IBEX Ribbon Due to the Solar Wind Structure

    NASA Astrophysics Data System (ADS)

    Swaczyna, Paweł; Bzowski, Maciej; Sokół, Justyna M.

    2016-08-01

    Observations of energetic neutral atoms (ENAs) allow for remote studies of the condition of plasma in the heliosphere and the neighboring local interstellar medium. The first results from the Interstellar Boundary Explorer (IBEX) revealed an arc-like enhancement of the ENA intensity in the sky, known as the ribbon. The ribbon was not expected from the heliospheric models prior to the launch of IBEX. One proposed explanation for the ribbon is the mechanism of secondary ENA emission. The ribbon reveals energy-dependent structure in the relative intensity along its circumference and in its position. That is, the geometric center of the ribbon varies systematically by about 10° in the energy range 0.7–4.3 keV. Here, we show by analytical modeling that this effect is a consequence of the helio-latitudinal structure of the solar wind reflected in the secondary ENAs. Along with a recently measured distance to the ribbon’s source just beyond the heliopause, our findings support the connection of the ribbon with the local interstellar magnetic field by the mechanism of secondary ENA emission. However, the magnitude of the center shift in the highest IBEX energy channel is much larger in the observations than expected from the modeling. This may be due to another, not currently recognized, process of ENA generation.

  12. Neutral and charged gallium clusters: structures, physical properties and implications for the melting features

    NASA Astrophysics Data System (ADS)

    Núñez, Sara; López, José M.; Aguado, Andrés

    2012-09-01

    We report the putative Global Minimum (GM) structures and electronic properties of GaN+, GaN and GaN- clusters with N = 13-37 atoms, obtained from first-principles density functional theory structural optimizations. The calculations include spin polarization and employ an exchange-correlation functional which accounts for van der Waals dispersion interactions (vdW-DFT). We find a wide diversity of structural motifs within the located GM, including decahedral, polyicosahedral, polytetrahedral and layered structures. The GM structures are also extremely sensitive to the number of electrons in the cluster, so that the structures of neutral and charged clusters differ for most sizes. The main magic numbers (clusters with an enhanced stability) are identified and interpreted in terms of electronic and geometric shell closings. The theoretical results are consistent with experimental abundance mass spectra of GaN+ and with photoelectron spectra of GaN-. The size dependence of the latent heats of melting, the shape of the heat capacity peaks, and the temperature dependence of the collision cross-sections, all measured for GaN+ clusters, are properly interpreted in terms of the calculated cohesive energies, spectra of configurational excitations, and cluster shapes, respectively. The transition from ``non-melter'' to ``magic-melter'' behaviour, experimentally observed between Ga30+ and Ga31+, is traced back to a strong geometry change. Finally, the higher-than-bulk melting temperatures of gallium clusters are correlated with a more typically metallic behaviour of the clusters as compared to the bulk, contrary to previous theoretical claims.We report the putative Global Minimum (GM) structures and electronic properties of GaN+, GaN and GaN- clusters with N = 13-37 atoms, obtained from first-principles density functional theory structural optimizations. The calculations include spin polarization and employ an exchange-correlation functional which accounts for van der Waals

  13. Orbital motion of dust particles in an rf magnetron discharge. Ion drag force or neutral atom wind force

    SciTech Connect

    Pal, A. F.; Ryabinkin, A. N.; Serov, A. O.; Dyatko, N. A.; Starostin, A. N.; Filippov, A. V.

    2012-03-15

    Microparticles with sizes up to 130 {mu}m have been confined and the velocity and diameter of particles in a plasma trap of an rf magnetron discharge with an arc magnetic field have been simultaneously measured. The motion of the gas induced by electron and ion cyclotron currents has been numerically simulated using the Navier-Stokes equation. The experimental and numerical results confirm the mechanism of the orbital motion of dust particles in the magnetron discharge plasma that is associated with the orbital motion of the neutral gas accelerated by electron and ion drift flows in crossed electric and magnetic fields.

  14. Lewis Structures Technology, 1988. Volume 3: Structural Integrity Fatigue and Fracture Wind Turbines HOST

    NASA Technical Reports Server (NTRS)

    1988-01-01

    The charter of the Structures Division is to perform and disseminate results of research conducted in support of aerospace engine structures. These results have a wide range of applicability to practioners of structural engineering mechanics beyond the aerospace arena. The specific purpose of the symposium was to familiarize the engineering structures community with the depth and range of research performed by the division and its academic and industrial partners. Sessions covered vibration control, fracture mechanics, ceramic component reliability, parallel computing, nondestructive evaluation, constitutive models and experimental capabilities, dynamic systems, fatigue and damage, wind turbines, hot section technology (HOST), aeroelasticity, structural mechanics codes, computational methods for dynamics, structural optimization, and applications of structural dynamics, and structural mechanics computer codes.

  15. Electrostatic solitary structures in the solar wind plasma

    NASA Astrophysics Data System (ADS)

    Singh, Satyavir; Singh Lakhina, Gurbax; Rubia, R.

    2016-07-01

    Recent observations have shown the existence of coherent electrostatic structures observed in the solar wind at 1 AU which could accelerate the charged particles. Electrostatic solitary waves are studied in a homogeneous, collisionless, and magnetized three-component plasma model relevant to the solar wind plasma. The theoretical model consists of hot protons, hot heavier ions (doubly charged helium ions) and suprathermal electrons having kappa distribution. Sagdeev pseudopotential technique is used to study the arbitrary amplitude ion-acoustic solitary wave. The study shows that when the heavier ion temperature is not exactly 4 times the proton temperature, we observe a new slow ion-acoustic mode in addition to the usual fast ion-acoustic mode. It is found that fast ion-acoustic mode supports only positive potential solitons. However, slow ion-acoustic mode is found to support both positive and negative potential solitons/double layers. The effect of various parameters such as the spectral index, κ, Mach number, temperature and number density of ions is studied on the evolution of ion-acoustic solitary waves as well as their existence domains. It is found that the limitation on the attainable amplitudes of fast ion-acoustic solitons is attributed to, that the number density of protons should remain real valued. While, for the slow ion-acoustic solitons the upper limit is provided by the requirement that the number density of heavier ion should remain real. In the presence of the double layers, the occurrence of the double layer limits the attainable amplitudes of the slow ion-acoustic solitons.

  16. Modeling the uptake of neutral organic chemicals on XAD passive air samplers under variable temperatures, external wind speeds and ambient air concentrations (PAS-SIM).

    PubMed

    Armitage, James M; Hayward, Stephen J; Wania, Frank

    2013-01-01

    The main objective of this study was to evaluate the performance and demonstrate the utility of a fugacity-based model of XAD passive air samplers (XAD-PAS) designed to simulate the uptake of neutral organic chemicals under variable temperatures, external wind speeds and ambient air concentrations. The model (PAS-SIM) simulates the transport of the chemical across the air-side boundary layer and within the sampler medium, which is segmented into a user-defined number of thin layers. Model performance was evaluated using data for polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs) from a field calibration study (i.e., active and XAD-PAS data) conducted in Egbert, Ontario, Canada. With some exceptions, modeled PAS uptake curves are in good agreement with the empirical PAS data. The results are highly encouraging, given the uncertainty in the active air sampler data used as input and other uncertainties related to model parametrization (e.g., sampler-air partition coefficients, the influence of wind speed on sampling rates). The study supports the further development and evaluation of the PAS-SIM model as a diagnostic (e.g., to aid interpretation of calibration studies and monitoring data) and prognostic (e.g., to inform design of future passive air sampling campaigns) tool. PMID:24175752

  17. Ion Scattering Studies of Silicon Surfaces and Interfaces: Structure and Neutralization.

    NASA Astrophysics Data System (ADS)

    Haight, Richard Alan

    This thesis chronicles three experiments which represent the major thrust of studies performed during my tenure as a graduate student at the State University of New York at Albany. Chapter 1 introduces the fundamental considerations of the physics of ion scattering and its applications to studies of surfaces, interfaces and ion neutralization. Basic formula are stated and the two atom model using the Coulomb interaction potential is developed as an approximate prediction of the surface peak intensity. The second chapter discusses a study of the neutralization of 75-180 KeV He ions scattered from clean and Cs covered Si (100); an experiment performed at Bell Laboratories. It is shown that ion neutralization occurs at the surface of the solid; the ion retains no memory of its journey within the bulk. It is also observed that the ion fraction exhibits no dependence upon takeoff angle, a result which differs markedly from the exponential angular dependence observed at lower velocities. Changes in the Si scattered ion fraction upon cesiation of the Si surface are correlated with the work function change observed by other workers. A model is proposed, and developed in mathematical detail, which includes resonant transitions to the motionally broadened He n=2 quantum level and is compared with the experimental data. The third chapter discusses an ion scattering study of the interfacial structure of the Si-SiO(,2) interface. It is shown that the oxide is stoichiometric to within (TURN)1 monolayer of the interface. Measurements to determine the magnitude and direction of the Si atomic displacements at the interface were compared with Monte Carlo computer simulations and show small lateral and larger vertical displacements in two layers. A model, consistent with the data, is proposed and the effects of these displacements are related qualitatively with theory. The fourth chapter describes a thin Si (111) crystal transmission channeling experiment. In this experiment, the use

  18. Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

    SciTech Connect

    Swanson, Kurt A.; Settembre, Ethan C.; Shaw, Christine A.; Dey, Antu K.; Rappuoli, Rino; Mandl, Christian W.; Dormitzer, Philip R.; Carfi, Andrea

    2012-02-07

    Respiratory syncytial virus (RSV), the main cause of infant bronchiolitis, remains a major unmet vaccine need despite more than 40 years of vaccine research. Vaccine candidates based on a chief RSV neutralization antigen, the fusion (F) glycoprotein, have foundered due to problems with stability, purity, reproducibility, and potency. Crystal structures of related parainfluenza F glycoproteins have revealed a large conformational change between the prefusion and postfusion states, suggesting that postfusion F antigens might not efficiently elicit neutralizing antibodies. We have generated a homogeneous, stable, and reproducible postfusion RSV F immunogen that elicits high titers of neutralizing antibodies in immunized animals. The 3.2-{angstrom} X-ray crystal structure of this substantially complete RSV F reveals important differences from homology-based structural models. Specifically, the RSV F crystal structure demonstrates the exposure of key neutralizing antibody binding sites on the surface of the postfusion RSV F trimer. This unanticipated structural feature explains the engineered RSV F antigen's efficiency as an immunogen. This work illustrates how structural-based antigen design can guide the rational optimization of candidate vaccine antigens.

  19. Spatial structure of low-frequency wind noise.

    PubMed

    Wilson, D Keith; Greenfield, Roy J; White, Michael J

    2007-12-01

    The distinguishing spatial properties of low-frequency microphone wind noise (turbulent pressure disturbances) are examined with a planar, 49-element array. Individual, propagating transient pressure disturbances are imaged by wavelet processing to the array data. Within a given frequency range, the wind disturbances are much smaller and less spatially coherent than sound waves. Conventional array processing techniques are particularly sensitive to wind noise when sensor separations are small compared to the acoustic wavelengths of interest. PMID:18247645

  20. Serum albumin binding of structurally diverse neutral organic compounds: data and models.

    PubMed

    Endo, Satoshi; Goss, Kai-Uwe

    2011-12-19

    Binding to serum albumin has a strong influence on freely dissolved, unbound concentrations of chemicals in vivo and in vitro. For neutral organic solutes, previous studies have suggested a log-log correlation between the albumin-water partition coefficient and the octanol-water partition coefficient (K(ow)) and postulated highly nonspecific binding that is mechanistically analogous to dissolution into solvents. These relationships and concepts were further explored in this study. Bovine serum albumin (BSA)-water partition coefficients (K(BSA/w)) were measured for 83 structurally diverse neutral organic chemicals in consistent experimental conditions. The correlation between log K(BSA/w) and log K(ow) was moderate, with R(2) = 0.76 and SD = 0.43. The log K(BSA/w) of low-polarity compounds including a series of chlorobenzenes and polycyclic aromatic hydrocarbons increased with log K(ow) linearly up to log K(ow) = 4-5, but then the linear relationship apparently broke off, and the increase became gradual. The fitting of polyparameter linear free energy relationship models with five solute descriptors was just comparable to that of the log K(ow) model (R(2) = 0.78-0.79, SD = 0.41-0.42); the relatively high SD obtained suggests that solvent dissolution models are not capable of modeling albumin binding accurately. A size limitation of the binding site(s) of albumin is suggested as a possible reason for the high SD. An equilibrium distribution model indicates that serum albumin generally has high contributions to the binding in the serum of polar compounds and relatively small low-polarity compounds, whereas albumin binding for large low-polarity compounds is outcompeted by the strong partitioning into lipids due to low relative affinity of albumin for these compounds. PMID:22070391

  1. Neutral Buoyancy Simulator: MSFC-Langley joint test of large space structures component assembly:

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Once the United States' space program had progressed from Earth's orbit into outerspace, the prospect of building and maintaining a permanent presence in space was realized. To accomplish this feat, NASA launched a temporary workstation, Skylab, to discover the effects of low gravity and weightlessness on the human body, and also to develop tools and equipment that would be needed in the future to build and maintain a more permanent space station. The structures, techniques, and work schedules had to be carefully designed to fit this unique construction site. The components had to be lightweight for transport into orbit, yet durable. The station also had to be made with removable parts for easy servicing and repairs by astronauts. All of the tools necessary for service and repairs had to be designed for easy manipulation by a suited astronaut. And construction methods had to be efficient due to limited time the astronauts could remain outside their controlled environment. In lieu of all the specific needs for this project, an environment on Earth had to be developed that could simulate a low gravity atmosphere. A Neutral Buoyancy Simulator (NBS) was constructed by NASA Marshall Space Flight Center (MSFC) in 1968. Since then, NASA scientists have used this facility to understand how humans work best in low gravity and also provide information about the different kinds of structures that can be built. With the help of the NBS, building a space station became more of a reality. In a joint venture between NASA/Langley Research Center in Hampton, VA and MSFC, the Assembly Concept for Construction of Erectable Space Structures (ACCESS) was developed and demonstrated at MSFC's NBS. The primary objective of this experiment was to test the ACCESS structural assembly concept for suitability as the framework for larger space structures and to identify ways to improve the productivity of space construction. Pictured is a demonstration of ACCESS.

  2. Dependence of Current-Sheet-like Structure on the Solar Wind Type from the ACE Observation

    NASA Astrophysics Data System (ADS)

    Arnold, L. E.; Li, G.

    2012-12-01

    Solar wind is an ideal testbed for studying various properties of magnetohydrodynamics turbulence (MHD), including its intermittent characteristics. One type of intermittent structure in the solar wind is current-sheet-like structures. These structures may originate from the solar surface or may emerge as a result of non-linear interactions in the solar wind. Depending on how they form, in particular whether or not they are formed in the solar wind, their occurrence rate may be a function of the solar wind type. In this work, we examine how the current sheet occurrence rate depend on the solar wind type. In classifying the solar wind type, we follow the criteria given in Zhao and Fisk (2009) and use the Advanced Composition Explorer (ACE) plasma data in the year of 2010. The current sheets are identified using the method developed in Li (2008) and Miao et al. (2011). Our results show that the occurrence rate has a different solar wind speed dependence for the coronal hole wind (CHW) and the non coronal hole wind (NCHW).

  3. Statistical features of the high-latitude ionospheric convection structure associated with enhanced solar wind fluctuations

    NASA Astrophysics Data System (ADS)

    Kim, H.; Lyons, L. R.; Ruohoniemi, J. M.; Frissell, N. A.

    2012-12-01

    While the IMF and solar wind dynamic pressure almost certainly play larger roles under most conditions, evidence has been recently found that Ultra Low Frequency (ULF) wave power in the solar wind has an additional substantial effect on the strength of convection within the polar caps, and on the nightside within both the aurora ionosphere and the plasma sheet. An initial study shows that the convection flows under enhanced solar wind fluctuations often appear to be more structured, with localized strong vortical features, than the convection under steady solar wind conditions. In this work, we statistically examine characteristic features of the ionospheric convection structure in terms of vortex patterns and how they are related to the convection enhancements during periods of enhanced solar wind fluctuations. Specifically, we examine whether enhanced solar wind ULF power will drive localized turbulence within enhanced convection cells while it increases convection strength at the same time. The results of this study will provide evidence for how solar wind ULF fluctuations can contribute to the solar wind energy transfer to the magnetosphere-ionosphere system. To determine the features of 2-D convection structure, we analyze the large-scale global convection maps derived from the SuperDARN observations with extensive radar echo coverage over a large portion of the high latitude ionosphere. Wind and ACE data are used for examination of solar wind and IMF conditions.

  4. A neutral pH thermal hydrolysis method for quantification of structured RNAs.

    PubMed

    Wilson, Stephen C; Cohen, Daniel T; Wang, Xin C; Hammond, Ming C

    2014-07-01

    Riboswitch aptamers adopt diverse and complex tertiary structural folds that contain both single-stranded and double-stranded regions. We observe that this high degree of secondary structure leads to an appreciable hypochromicity that is not accounted for in the standard method to calculate extinction coefficients using nearest-neighbor effects, which results in a systematic underestimation of RNA concentrations. Here we present a practical method for quantifying riboswitch RNAs using thermal hydrolysis to generate the corresponding pool of mononucleotides, for which precise extinction coefficients have been measured. Thermal hydrolysis can be performed at neutral pH without reaction quenching, avoids the use of nucleases or expensive fluorescent dyes, and does not require generation of calibration curves. The accuracy of this method for determining RNA concentrations has been validated using quantitative (31)P-NMR calibrated to an external standard. We expect that this simple procedure will be generally useful for the accurate quantification of any sequence-defined RNA sample, which is often a critical parameter for in vitro binding and kinetic assays. PMID:24860014

  5. Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1

    SciTech Connect

    Pancera, Marie; McLellan, Jason S.; Wu, Xueling; Zhu, Jiang; Changela, Anita; Schmidt, Stephen D.; Yang, Yongping; Zhou, Tongqing; Phogat, Sanjay; Mascola, John R.; Kwong, Peter D.

    2010-11-03

    HIV-1 resists neutralization by most antibodies. Two somatically related human antibodies, PG9 and PG16, however, each neutralize 70 to 80% of circulating HIV-1 isolates. Here we present the structure of the antigen-binding fragment of PG16 in monoclinic and orthorhombic lattices at 2.4 and 4.0 {angstrom}, respectively, and use a combination of structural analysis, paratope dissection, and neutralization assessment to determine the functional relevance of three unusual PG9/PG16 features: N-linked glycosylation, extensive affinity maturation, and a heavy chain-third complementarity-determining region (CDR H3) that is one of the longest observed in human antibodies. Glycosylation extended off the side of the light chain variable domain and was not required for neutralization. The CDR H3 formed an axe-shaped subdomain, which comprised 42% of the CDR surface, with the axe head looming {approx}20 {angstrom} above the other combining loops. Comprehensive sets of chimeric swaps between PG9 and PG16 of light chain, heavy chain, and CDR H3 were employed to decipher structure-function relationships. Chimeric swaps generally complemented functionally, with differences in PG9/PG16 neutralization related primarily to residue differences in CDR H3. Meanwhile, chimeric reversions to genomic V genes showed isolate-dependent effects, with affinity maturation playing a significant role in augmenting neutralization breadth (P = 0.036) and potency (P < 0.0001). The structural and functional details of extraordinary CDR H3 and extensive affinity maturation provide insights into the neutralization mechanism of and the elicitation pathway for broadly neutralizing antibodies like PG9 and PG16.

  6. Extreme winds and tornadoes: design and evaluation of buildings and structures

    SciTech Connect

    McDonald, J.R.

    1985-01-01

    The general provisions of ANSI A58.1-1982 are explained in detail. As mentioned above, these procedures may be used to determine design wind loads on structures from extreme winds, hurricane and tornado winds. Treatment of atmospheric pressure change loads are discussed, including recommendations for venting a building, if necessary, and the effects of rate of pressure change on HVAC systems. Finally, techniques for evaluating existing facilities are described.

  7. Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F

    SciTech Connect

    McLellan, Jason S.; Chen, Man; Chang, Jung-San; Yang, Yongping; Kim, Albert; Graham, Barney S.; Kwong, Peter D.

    2010-11-19

    Respiratory syncytial virus (RSV) is a major cause of pneumonia and bronchiolitis in infants and elderly people. Currently there is no effective vaccine against RSV, but passive prophylaxis with neutralizing antibodies reduces hospitalizations. To investigate the mechanism of antibody-mediated RSV neutralization, we undertook structure-function studies of monoclonal antibody 101F, which binds a linear epitope in the RSV fusion glycoprotein. Crystal structures of the 101F antigen-binding fragment in complex with peptides from the fusion glycoprotein defined both the extent of the linear epitope and the interactions of residues that are mutated in antibody escape variants. The structure allowed for modeling of 101F in complex with trimers of the fusion glycoprotein, and the resulting models suggested that 101F may contact additional surfaces located outside the linear epitope. This hypothesis was supported by surface plasmon resonance experiments that demonstrated 101F bound the peptide epitope {approx}16,000-fold more weakly than the fusion glycoprotein. The modeling also showed no substantial clashes between 101F and the fusion glycoprotein in either the pre- or postfusion state, and cell-based assays indicated that 101F neutralization was not associated with blocking virus attachment. Collectively, these results provide a structural basis for RSV neutralization by antibodies that target a major antigenic site on the fusion glycoprotein.

  8. Neutral Buoyancy Simulator-NB32-Assembly of Large Space Structure

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Once the United States' space program had progressed from Earth's orbit into outerspace, theprospect of building and maintaining a permanent presence in space was realized. To accomplish this feat, NASA launched a temporary workstation, Skylab, to discover the effects of low gravity and weightlessness on the human body, and also to develop tools and equipment that would be needed in the future to build and maintain a more permanent space station. The structures, techniques, and work schedules had to be carefully designed to fit this unique construction site. The components had to be lightweight for transport into orbit, yet durable. The station also had to be made with removable parts for easy servicing and repairs by astronauts. All of the tools necessary for service and repairs had to be designed for easy manipulation by a suited astronaut. Construction methods had to be efficient due to the limited time the astronauts could remain outside their controlled environment. In lieu of all the specific needs for this project, an environment on Earth had to be developed that could simulate a low gravity atmosphere. A Neutral Buoyancy Simulator (NBS) was constructed by NASA's Marshall Space Flight Center (MSFC) in 1968. Since then, NASA scientists have used this facility to understand how humans work best in low gravity and also provide information about the different kinds of structures that can be built. Pictured is a Massachusetts Institute of Technology (MIT) student working in a spacesuit on the Experimental Assembly of Structures in Extravehicular Activity (EASE) project which was developed as a joint effort between MFSC and MIT. The EASE experiment required that crew members assemble small components to form larger components, working from the payload bay of the space shuttle. The MIT student in this photo is assembling two six-beam tetrahedrons.

  9. Numerical simulation of tornado wind loading on structures

    NASA Technical Reports Server (NTRS)

    Maiden, D. E.

    1976-01-01

    A numerical simulation of a tornado interacting with a building was undertaken in order to compare the pressures due to a rotational unsteady wind with that due to steady straight winds used in design of nuclear facilities. The numerical simulations were performed on a two-dimensional compressible hydrodynamics code. Calculated pressure profiles for a typical building were then subjected to a tornado wind field and the results were compared with current quasisteady design calculations. The analysis indicates that current design practices are conservative.

  10. Neutral Mononuclear Copper(I) Complexes: Synthesis, Crystal Structures, and Photophysical Properties.

    PubMed

    Sun, Yinghui; Lemaur, Vincent; Beltrán, Juan I; Cornil, Jérôme; Huang, Jianwen; Zhu, Juntong; Wang, Yun; Fröhlich, Roland; Wang, Haibo; Jiang, Lin; Zou, Guifu

    2016-06-20

    Neutral green-emitting four-coordinate Cu(I) complexes with general formula POPCu(NN), where POP = bis[2-(diphenylphosphino)phenyl]ether and NN = substituted 2-pyridine-1,2,4-triazole ligands, were synthesized. The crystal structures of (POPCuMeCN)(+)(PF6)(-) (1), POPCuPhPtp (2a, PhPtp = 2-(5-phenyl-2H-[1,2,4]triazol-3-yl)-pyridine), and POPCu(3,5-2FPhPtp) (2d, 3,5-2FPhPtp = 2-(5-(3,5-difluorophenyl)-2H-1,2,4-triazol-3-yl)pyridine) were determined by single-crystal X-ray diffraction analysis. The electronic and photophysical properties of the complexes were examined by UV-vis, steady-state, and time-resolved spectroscopy. At room temperature, weak emission was observed in solution, while in the solid state, all complexes exhibit intense green emission with quantum yield up to 0.54. The electronic and photophysical properties were further supported by calculation performed at the (time-dependent) density functional theory level. One of the complexes was also tested as dopant in electroluminescent devices. PMID:27232266

  11. Neutral "Cp-Free" Silyl-Lanthanide(II) Complexes: Synthesis, Structure, and Bonding Analysis.

    PubMed

    Zitz, Rainer; Hlina, Johann; Gatterer, Karl; Marschner, Christoph; Szilvási, Tibor; Baumgartner, Judith

    2015-07-20

    Complexes featuring lanthanide silicon bonds represent a research area still in its infancy. Herein, we report a series of Cp-free lanthanide (+II) complexes bearing σ-bonded silyl ligands. By reactions of LnI2 (Ln = Yb, Eu, Sm) either with a 1,4-oligosilanyl dianion [K-Si(SiMe3)2SiMe2SiMe2Si(SiMe3)2-K)] (1) or with 2 (Me3Si)3SiK (3) the corresponding neutral metallacyclopentasilanes ({Me2Si(Me3Si)2Si}2)Ln·(THF)4 (Ln = Yb (2a), Eu (2b), Sm (2c)), or the disilylated complexes ({Me3Si}3Si)2Ln·(THF)3 (Ln = Yb (4a), Eu (4b), Sm (4c)), were selectively obtained. Complexes 2b, 2c, 4b, and 4c represent the first examples of structurally characterized Cp-free Eu and Sm complexes with silyl ligands. In both series, a linear correlation was observed between the Ln-Si bond lengths and the covalent radii of the corresponding lanthanide metals. Density functional theory calculations were also carried out for complexes 2a-c and 4a-c to elucidate the bonding situation between the Ln(+II) centers and Si. PMID:26132550

  12. Neutral “Cp-Free” Silyl-Lanthanide(II) Complexes: Synthesis, Structure, and Bonding Analysis

    PubMed Central

    2015-01-01

    Complexes featuring lanthanide silicon bonds represent a research area still in its infancy. Herein, we report a series of Cp-free lanthanide (+II) complexes bearing σ-bonded silyl ligands. By reactions of LnI2 (Ln = Yb, Eu, Sm) either with a 1,4-oligosilanyl dianion [K-Si(SiMe3)2SiMe2SiMe2Si(SiMe3)2-K)] (1) or with 2 (Me3Si)3SiK (3) the corresponding neutral metallacyclopentasilanes ({Me2Si(Me3Si)2Si}2)Ln·(THF)4 (Ln = Yb (2a), Eu (2b), Sm (2c)), or the disilylated complexes ({Me3Si}3Si)2Ln·(THF)3 (Ln = Yb (4a), Eu (4b), Sm (4c)), were selectively obtained. Complexes 2b, 2c, 4b, and 4c represent the first examples of structurally characterized Cp-free Eu and Sm complexes with silyl ligands. In both series, a linear correlation was observed between the Ln–Si bond lengths and the covalent radii of the corresponding lanthanide metals. Density functional theory calculations were also carried out for complexes 2a–c and 4a–c to elucidate the bonding situation between the Ln(+II) centers and Si. PMID:26132550

  13. Synthesis, structural characterisation and antibacterial activity of Ag+-doped fluorapatite nanomaterials prepared by neutralization method

    NASA Astrophysics Data System (ADS)

    Stanić, Vojislav; Radosavljević-Mihajlović, Ana S.; Živković-Radovanović, Vukosava; Nastasijević, Branislav; Marinović-Cincović, Milena; Marković, Jelena P.; Budimir, Milica D.

    2015-05-01

    Silver doped fluorapatite nanopowders were synthesised by neutralization method, which consists of dissolving Ag2O in solution of HF and H3PO4 and addition to suspension of Ca(OH)2. The powder XRD, SEM and FTIR studies indicated the formation of a fluorapatite nanomaterials with average length of the particles is about 80 nm and a width of about 15 nm. The FTIR studies show that carbonate content in samples is very small and carbonte ions substitute both phosphate and hydroxyl groups in the crystal structure of samples, forming AB-type fluorapatite. Antibacterial studies have demonstrated that all Ag+-doped fluorapatite samples exhibit bactericidal effect against pathogens: Staphylococcus aureus, Micrococcus luteus and Kllebsiela pneumoniae. Antibacterial activity increased with the increase of Ag+ in the samples. The atomic force microscopy studies revealed extensive damage to the bacterial cell envelops in the presence of Ag+-doped fluorapatite particles which may lead to their death. The synthesized Ag+-doped fluorapatite nanomaterials are promising as antibacterial biomaterials in orthopedics and dentistry.

  14. Reconstruction of Helio-Latitudinal Structure of the Solar Wind Proton Speed and Density

    NASA Astrophysics Data System (ADS)

    Sokół, Justyna M.; Swaczyna, Paweł; Bzowski, Maciej; Tokumaru, Munetoshi

    2015-09-01

    The modeling of the heliosphere requires continuous three-dimensional solar wind data. The in-situ out-of-ecliptic measurements are very rare, so that other methods of solar wind detection are needed. We use the remote-sensing data of the solar wind speed from observations of interplanetary scintillation (IPS) to reconstruct spatial and temporal structures of the solar wind proton speed from 1985 to 2013. We developed a method of filling the data gaps in the IPS observations to obtain continuous and homogeneous solar wind speed records. We also present a method to retrieve the solar wind density from the solar wind speed, utilizing the invariance of the solar wind dynamic pressure and energy flux with latitude. To construct the synoptic maps of the solar wind speed we use the decomposition into spherical harmonics of each of the Carrington rotation map. To fill the gaps in time we apply the singular spectrum analysis to the time series of the coefficients of spherical harmonics. We obtained helio-latitudinal profiles of the solar wind proton speed and density over almost three recent solar cycles. The accuracy in the reconstruction is, due to computational limitations, about 20 %. The proposed methods allow us to improve the spatial and temporal resolution of the model of the solar wind parameters presented in our previous paper (Sokół et al., Solar Phys. 285, 167, 2013) and give a better insight into the time variations of the solar wind structure. Additionally, the solar wind density is reconstructed more accurately and it fits better to the in-situ measurements from Ulysses.

  15. Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope

    PubMed Central

    Austin, S. Kyle; Dowd, Kimberly A.; Shrestha, Bimmi; Nelson, Christopher A.; Edeling, Melissa A.; Johnson, Syd; Pierson, Theodore C.; Diamond, Michael S.; Fremont, Daved H.

    2012-01-01

    We previously developed a panel of neutralizing monoclonal antibodies against Dengue virus (DENV)-1, of which few exhibited inhibitory activity against all DENV-1 genotypes. This finding is consistent with reports observing variable neutralization of different DENV strains and genotypes using serum from individuals that experienced natural infection or immunization. Herein, we describe the crystal structures of DENV1-E111 bound to a novel CC′ loop epitope on domain III (DIII) of the E protein from two different DENV-1 genotypes. Docking of our structure onto the available cryo-electron microscopy models of DENV virions revealed that the DENV1-E111 epitope was inaccessible, suggesting that this antibody recognizes an uncharacterized virus conformation. While the affinity of binding between DENV1-E111 and DIII varied by genotype, we observed limited correlation with inhibitory activity. Instead, our results support the conclusion that potent neutralization depends on genotype-dependent exposure of the CC′ loop epitope. These findings establish new structural complexity of the DENV virion, which may be relevant for the choice of DENV strain for induction or analysis of neutralizing antibodies in the context of vaccine development. PMID:23055922

  16. The measurement of the ground wind structure at Wallops Island

    NASA Technical Reports Server (NTRS)

    Tielman, H. W.

    1981-01-01

    The mean and turbulence characteristics of the surface wind measured near the Atlantic coast were measured. The experimental data were acquired from a 76 meter tall instrumented micrometeorological tower. Mean wind and turbulence measurements were made with two types of instrumentation consisting of cup vane and temperature probes, primarily used for mean profile measurements of velocity and temperature respectively. The second system, a hot film and thermocouple system, was used for measurement of turbulence variances and covariances and spectra. The cup vane system was used to acquire data from all wind directions, while the hot film system was primarily used for turbulence measurements from the two prevailing wind directions, south and northwest. The micrometeorological tower is a self standing nonguyed tower with five working platforms at 15.2m (50 ft.) intervals, with cup vane and aspirated temperature probes mounted at each platform.

  17. Lawn Structured Triboelectric Nanogenerators for Scavenging Sweeping Wind Energy on Rooftops.

    PubMed

    Zhang, Lei; Zhang, Binbin; Chen, Jun; Jin, Long; Deng, Weili; Tang, Junfeng; Zhang, Haitao; Pan, Hong; Zhu, Minhao; Yang, Weiqing; Wang, Zhong Lin

    2016-02-24

    A novel triboelectric nanogenerator (TENG) is designed, based on flexible and transparent vertical-strip arrays, for environmental wind-energy harvesting. Given the low cost, simple structure, and wide applicability, the TENGs present a green alternative to traditional methods used for large-scale wind-energy harvesting. PMID:26669627

  18. Structure and chain conformation of a neutral intracellular heteropolysaccharide from mycelium of Paecilomyces cicadae.

    PubMed

    Wei, Chao-yang; Li, Wei-qi; Shao, Shuang-shuang; He, Liang; Cheng, Junwen; Han, Sufang; Liu, Yu

    2016-01-20

    A neutral heteropolysaccharide (PCIPS2) was isolated and purified from mycelium of Paecilomyces cicadae, which was investigated to be mainly composed of D-mannose, L-rhamnose, 3-O-methyl-D-galactose, D-glucose and D-galactose with a molar ratio of 47.9:3.1:6.4:0.9:0.8. It had a backbone of 1,4-linked α-L-Rhap residues and 1,6-linked α-D-Manp residues with branches at O-3 of α-D-Manp residues. Its side chain was comprised of minor terminal β-D-glucose and 1,4-linked α-3-O-Me-D-Galp residues terminated by α-D-galactose. Furthermore, its chain information on the values of weight-average molar mass (Mw), root mean square radius ([Formula: see text]), hydrodynamic radius (Rh) and intrinsic viscosity ([η]) for PCIPS2 were analyzed to be 3.09 × 10(4)g/mol, 7.8 nm, 3.6 nm and 8.5 mL/g, respectively. The structural exponent α of 0.57 indicated that PCIPS2 existed as a flexible chain conformation with a coil-like structure in 0.1M NaNO3 at 25 °C. In terms of known theory for worm-like chains, the model parameters for PCIPS2 were as following: molar mass per unit contour length (ML) = 379 nm(-1), persistence length (q) = 0.74 nm and hydrodynamic diameter of cylinder (d) = 0.82 nm, which were further evidenced by atomic force microscopy (AFM). PMID:26572406

  19. Neutral Buoyancy Simulator: MSFC-Langley joint test of large space structures component assembly:

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Once the United States' space program had progressed from Earth's orbit into outerspace, the prospect of building and maintaining a permanent presence in space was realized. To accomplish this feat, NASA launched a temporary workstation, Skylab, to discover the effects of low gravity and weightlessness on the human body, and also to develop tools and equipment that would be needed in the future to build and maintain a more permanent space station. The structures, techniques, and work schedules had to be carefully designed to fit this unique construction site. The components had to be lightweight for transport into orbit, yet durable. The station also had to be made with removable parts for easy servicing and repairs by astronauts. All of the tools necessary for service and repairs had to be designed for easy manipulation by a suited astronaut. And construction methods had to be efficient due to limited time the astronauts could remain outside their controlled environment. In lieu of all the specific needs for this project, an environment on Earth had to be developed that could simulate a low gravity atmosphere. A Neutral Buoyancy Simulator (NBS) was constructed by NASA Marshall Space Flight Center (MSFC) in 1968. Since then, NASA scientists have used this facility to understand how humans work best in low gravity and also provide information about the different kinds of structures that can be built. Another facet of the space station would be electrical cornectors which would be used for powering tools the astronauts would need for construction, maintenance and repairs. Shown is an astronaut training during an underwater electrical connector test in the NBS.

  20. Structural analysis of wind turbine rotors for NSF-NASA Mod-0 wind power system

    NASA Technical Reports Server (NTRS)

    Spera, D. A.

    1975-01-01

    Preliminary estimates of vibratory loads and stresses in hingeless and teetering rotors for the proposed 100-kW wind power system are presented. Stresses in the shank areas of the 19-m (62.5-ft) blades are given for static, rated, and overload conditions. The teetering rotor has substantial advantages over the hingeless rotor with respect to shank stresses, fatigue life, and tower loading. A teetering rotor will probably be required in order to achieve a long service life in a large wind turbine exposed to periodic overload conditions.

  1. Structure of magnetic field in the solar wind

    NASA Technical Reports Server (NTRS)

    Chertkov, A. D.

    1995-01-01

    This work is concerned with empirical data on magnetic field in the solar wind in frame of a concept of dissipative solar wind, developed in papers (Solar Wind 7 Conf., Pergamon Press, 1992, 165 and 1992 STEP/5th COSPAR Coll. Pergamon Press, 1994, 117; 235; 803). Interplanetary magnetic fields should be classified with respect to their origin. It is very important for all the theoretical problems from the necessity to specify correctly boundary and initial conditions: the magnetic field must be sewed with its source. One should select the field, connected directly with the Sun (stretched out from it), and the field of moving electric currents. It occured central in discussion about the velocity of Alfven waves, probably warming up the solar wind, relative to the Sun, the magnetic field and solar wind plasma. The selection problem corresponds to an inverse problem and obviously has no single solution. The dissipative model of the solar wind introduce the slipping and leakage of plasma relative to magnetic field. There are no 'interplanetary current sheets' in it. But temporal fluctuations from the filamentation of electric currents play the key role. As a whole, the new concept requires the re-interpretation of main objects in the interplanetary magnetic field.

  2. Structural Flexibility of a Conserved Antigenic Region in Hepatitis C Virus Glycoprotein E2 Recognized by Broadly Neutralizing Antibodies

    PubMed Central

    Meola, Annalisa; Tarr, Alexander W.; England, Patrick; Meredith, Luke W.; McClure, C. Patrick; Foung, Steven K. H.; McKeating, Jane A.; Ball, Jonathan K.; Rey, Felix A.

    2014-01-01

    ABSTRACT Neutralizing antibodies (NAbs) targeting glycoprotein E2 are important for the control of hepatitis C virus (HCV) infection. One conserved antigenic site (amino acids 412 to 423) is disordered in the reported E2 structure, but a synthetic peptide mimicking this site forms a β-hairpin in complex with three independent NAbs. Our structure of the same peptide in complex with NAb 3/11 demonstrates a strikingly different extended conformation. We also show that residues 412 to 423 are essential for virus entry but not for E2 folding. Together with the neutralizing capacity of the 3/11 Fab fragment, this indicates an unexpected structural flexibility within this epitope. NAbs 3/11 and AP33 (recognizing the extended and β-hairpin conformations, respectively) display similar neutralizing activities despite converse binding kinetics. Our results suggest that HCV utilizes conformational flexibility as an immune evasion strategy, contributing to the limited immunogenicity of this epitope in patients, similar to the conformational flexibility described for other enveloped and nonenveloped viruses. IMPORTANCE Approximately 180 million people worldwide are infected with hepatitis C virus (HCV), and neutralizing antibodies play an important role in controlling the replication of this major human pathogen. We show here that one of the most conserved antigenic sites within the major glycoprotein E2 (amino acids 412 to 423), which is disordered in the recently reported crystal structure of an E2 core fragment, can adopt different conformations in the context of the infectious virus particle. Recombinant Fab fragments recognizing different conformations of this antigenic site have similar neutralization activities in spite of converse kinetic binding parameters. Of note, an antibody response targeting this antigenic region is less frequent than those targeting other more immunogenic regions in E2. Our results suggest that the observed conformational flexibility in this

  3. Wind Energy's New Role in Supplying the World's Energy: What Role Will Structural Health Monitoring Play?

    SciTech Connect

    Butterfield, S.; Sheng, S.; Oyague, F.

    2009-12-01

    Wind energy installations are leading all other forms of new energy installations in the United States and Europe. In Europe, large wind plants are supplying as much as 25% of Denmark's energy needs and 8% of the electric needs for Germany and Spain, who have more ambitious goals on the horizon. Although wind energy only produces about 2% of the current electricity demand in the United States, the U.S. Department of Energy, in collaboration with wind industry experts, has drafted a plan that would bring the U.S. installed wind capacity up to 20% of the nation's total electrical supply. To meet these expectations, wind energy must be extremely reliable. Structural health monitoring will play a critical role in making this goal successful.

  4. Gas-Phase Neutral Binary Oxide Clusters: Distribution, Structure, and Reactivity toward CO.

    PubMed

    Wang, Zhe-Chen; Yin, Shi; Bernstein, Elliot R

    2012-09-01

    Neutral binary (vanadium-cobalt) oxide clusters are generated and detected in the gas phase for the first time. Their reactivities toward carbon monoxide (CO) are studied both experimentally and theoretically. Experimental results suggest that neutral VCoO4 can react with CO to generate VCoO3 and CO2. Density functional theory studies show parallel results as well as provide detailed reaction mechanisms. PMID:26292125

  5. Latitudinal structure and north-south asymmetry of the solar wind from Lyman-alpha remote sensing by SWAN

    NASA Astrophysics Data System (ADS)

    Bzowski, M.; Mäkinen, T.; Kyrölä, E.; Summanen, T.; Quémerais, E.

    2003-09-01

    Based on SWAN/SOHO observations carried out during 1996-2002, we analyze latitudinal profiles of the heliospheric backscatter Lyman-alpha radiation. We use these results to investigate the ionization field of neutral hydrogen in the inner heliosphere and the latitudinal distribution of the solar wind mass flux. The the depth and latitudinal range of the equatorial depression in the Lyman-alpha backscatter glow (the so-called ``groove'') are correlated with the corresponding parameters of the ionization field. We show that the groove is entirely due to latitudinal anisotropy of the solar wind, since, as we are able to demonstrate, the photoionization rate remains spherically symmetric throughout the solar cycle. During the last solar minimum the groove was well developed and stable. During the ascending phase of solar activity, it expanded in latitude (first south, then north), and disappeared altogether during the solar maximum. Shortly after the maximum it reappeared, but its structure was more complex than during the ascending phase. The groove feature is correlated with the equatorial band occupied by the slow solar wind, while the polar maxima of the Lyman-alpha intensity correspond to the fast solar wind from the polar holes. The groove observations (supported by appropriate modeling) show that during the last solar minimum the mass flux of the fast solar wind from the north and south polar holes were different from each other: a true north-south asymmetry between the polar regions was detected. During the solar minimum, the area occupied by the slow solar wind was quite stable and offset slightly to the south with respect to the solar equator: it extended to about 30° N and 35° S from the beginning of observations in May 1996 till 1998. Then it expanded by about 10degr north and south, and subsequently migrated towards southern latitudes, so that it engulfed the south pole in May/June 2000. The north region of the fast wind survived longer and disappeared

  6. Chromospheric Structure and Wind Acceleration in Zeta Aur Stars

    NASA Astrophysics Data System (ADS)

    Bennett, Philip D.

    2001-11-01

    This NASA grant supported an analysis of the variability of the wind of the supergiant primary star (K4 Ib) in the eclipsing binary Zeta Aurigae (Zeta Aur). In the ultraviolet, the main-sequence companion star (B5 V) dominates the observed flux, and therefore serves as a convenient probe of the cool supergiant's wind. This study utilized the extensive set of (100+) ultraviolet spectroscopic observations obtained with the International Ultraviolet Explorer (IUE) satellite over its operational lifetime of 1978-1995. Although the resolution of IUE is limited (about 25 km/s), it is adequate to resolve variability in the wind features in Zeta Aur's ultraviolet spectrum, which are blueshifted 70 km/s from line center. Our analysis used the tau-v technique of Cardelli and Savage, which makes full use of the available line profile information. We find that the wind column densities vary by up to an order of magnitude over time. These results are being written up for submission to the Astrophysical Journal as the third paper of a series on the chromosphere and wind of Zeta Aurigae. The first two papers report on the construction of mean chromosphere and wind models respectively, based on HST/GHRS observations and funded by STScI. The third paper - this research - reports on variability of the Zeta Aur wind as determined from our analysis of the long IUE time series. This paper will be completed within the next three months; the delay in publication was to allow the completion of Papers 1 and 2, which logically precede the present work. Therefore, an additional no-cost extension was requested in order to ensure budgeted funds remain available for publication of this work. Unfortunately, this request was denied, and so I am forced to write this final report before publication of Paper 3. Regardless, this paper will be submitted for publication within the next three months.

  7. Chromospheric Structure and Wind Acceleration in Zeta Aur Stars

    NASA Technical Reports Server (NTRS)

    Bennett, Philip D.

    2001-01-01

    This NASA grant supported an analysis of the variability of the wind of the supergiant primary star (K4 Ib) in the eclipsing binary Zeta Aurigae (Zeta Aur). In the ultraviolet, the main-sequence companion star (B5 V) dominates the observed flux, and therefore serves as a convenient probe of the cool supergiant's wind. This study utilized the extensive set of (100+) ultraviolet spectroscopic observations obtained with the International Ultraviolet Explorer (IUE) satellite over its operational lifetime of 1978-1995. Although the resolution of IUE is limited (about 25 km/s), it is adequate to resolve variability in the wind features in Zeta Aur's ultraviolet spectrum, which are blueshifted 70 km/s from line center. Our analysis used the tau-v technique of Cardelli and Savage, which makes full use of the available line profile information. We find that the wind column densities vary by up to an order of magnitude over time. These results are being written up for submission to the Astrophysical Journal as the third paper of a series on the chromosphere and wind of Zeta Aurigae. The first two papers report on the construction of mean chromosphere and wind models respectively, based on HST/GHRS observations and funded by STScI. The third paper - this research - reports on variability of the Zeta Aur wind as determined from our analysis of the long IUE time series. This paper will be completed within the next three months; the delay in publication was to allow the completion of Papers 1 and 2, which logically precede the present work. Therefore, an additional no-cost extension was requested in order to ensure budgeted funds remain available for publication of this work. Unfortunately, this request was denied, and so I am forced to write this final report before publication of Paper 3. Regardless, this paper will be submitted for publication within the next three months.

  8. The plasma structure of coronal hole solar wind: Origins and evolution

    NASA Astrophysics Data System (ADS)

    Borovsky, Joseph E.

    2016-06-01

    Whereas slow solar wind is known to be highly structured, the fast (coronal hole origin) wind is usually considered to be homogeneous. Using measurements from Helios 1 + 2, ACE, Wind, and Ulysses, structure in the coronal hole origin solar wind is examined from 0.3 AU to 2.3 AU. Care is taken to collect and analyze intervals of "unperturbed coronal hole plasma." In these intervals, solar wind structure is seen in the proton number density, proton temperature, proton specific entropy, magnetic field strength, magnetic field to density ratio, electron heat flux, helium abundance, heavy-ion charge-state ratios, and Alfvenicity. Typical structure amplitudes are factors of 2, far from homogeneous. Variations are also seen in the solar wind radial velocity. Using estimates of the motion of the solar wind origin footpoint on the Sun for the various spacecraft, the satellite time series measurements are converted to distance along the photosphere. Typical variation scale lengths for the solar wind structure are several variations per supergranule. The structure amplitude and structure scale sizes do not evolve with distance from the Sun from 0.3 to 2.3 AU. An argument is quantified that these variations are the scale expected for solar wind production in open magnetic flux funnels in coronal holes. Additionally, a population of magnetic field foldings (switchbacks, reversals) in the coronal hole plasma is examined: this population evolves with distance from the Sun such that the magnetic field is mostly Parker spiral aligned at 0.3 AU and becomes more misaligned with distance outward.

  9. Al and Ge simultaneous oxidation using neutral beam post-oxidation for formation of gate stack structures

    SciTech Connect

    Ohno, Takeo; Nakayama, Daiki; Samukawa, Seiji

    2015-09-28

    To obtain a high-quality Germanium (Ge) metal–oxide–semiconductor structure, a Ge gate stacked structure was fabricated using neutral beam post-oxidation. After deposition of a 1-nm-thick Al metal film on a Ge substrate, simultaneous oxidation of Al and Ge was carried out at 300 °C, and a Ge oxide film with 29% GeO{sub 2} content was obtained by controlling the acceleration bias power of the neutral oxygen beam. In addition, the fabricated AlO{sub x}/GeO{sub x}/Ge structure achieved a low interface state density of less than 1 × 10{sup 11 }cm{sup −2 }eV{sup −1} near the midgap.

  10. Ab initio molecular-orbital study of structures and energetics of Si3H3 neutral and anion

    NASA Astrophysics Data System (ADS)

    Saitoh, Toshiaki; Naoe, Toshimasa; Ikuta, Shigeru

    2005-05-01

    The geometric structures and isomeric stabilities of various stationary points in Si3H3 neutral and its anion are investigated at the coupled-cluster singles, doubles (triples) [CCSD(T)] level of theory. For geometrical surveys, the basis sets used are of the Dunning's correlation consistent basis sets of triple-zeta quality for the neutral. To the anions, the Dunning's correlation consistent basis sets of double-zeta quality with diffuse functions are applied. For the three lower-lying anion isomers, the Dunning's correlation consistent basis sets of triple-zeta quality with diffuse functions (aug-cc-pVTZ) are also used. The final energies for the optimized stationary points are calculated at the CCSD(T) level of theory with the aug-cc-pVTZ basis sets. The basis sets of 6-311++G(3df,2pd) were also used for the lower-lying anion isomers. The Gaussian-2 method was performed only for the lower-lying anion isomers to clarify the relative stabilities. The global minimum neutral 1 (C1:A2) has an unsymmetrical hydrogen-bridged bond; the conformer 2 in Cs symmetry is a saddle point connecting the two equivalent isomers 1. Two lower-lying isomers (3 and 4) are also predicted within the energy range of 20kJ/mol. In the anion, however, the conformer 4 (Cs:A'1) with five formal valence electrons is a global minimum. Two more isomers (2 and 3) lie within 20kJ/mol as in the neutral; the conformer 1 converts to the isomer 2. The quartets for the neutrals and diradical triplets for the anions were further studied; lower-lying quartets and triplets, competing with the corresponding doublet and singlet, respectively, were not found in the present systems. The vertical and adiabatic electron affinities of the global minimum neutral 1, producing the second lowest-lying anion isomer 2, amount to 2.18 and 2.35 eV, respectively, at the CCSD(T)/aug-cc-pVTZ level of theory. The electron addition to the third lowest-lying neutral isomer 4 produces the largest vertical electron affinities

  11. Structural basis for type VI secreted peptidoglycan dl-endopeptidase function, specificity and neutralization in Serratia marcescens

    PubMed Central

    Srikannathasan, Velupillai; English, Grant; Bui, Nhat Khai; Trunk, Katharina; O’Rourke, Patrick E. F.; Rao, Vincenzo A.; Vollmer, Waldemar; Coulthurst, Sarah J.; Hunter, William N.

    2013-01-01

    Some Gram-negative bacteria target their competitors by exploiting the type VI secretion system to extrude toxic effector proteins. To prevent self-harm, these bacteria also produce highly specific immunity proteins that neutralize these antagonistic effectors. Here, the peptidoglycan endopeptidase specificity of two type VI secretion-system-associated effectors from Serratia marcescens is characterized. These small secreted proteins, Ssp1 and Ssp2, cleave between γ-d-glutamic acid and l-meso-diaminopimelic acid with different specificities. Ssp2 degrades the acceptor part of cross-linked tetratetrapeptides. Ssp1 displays greater promiscuity and cleaves monomeric tripeptides, tetrapeptides and pentapeptides and dimeric tetratetra and tetrapenta muropeptides on both the acceptor and donor strands. Functional assays confirm the identity of a catalytic cysteine in these endopeptidases and crystal structures provide information on the structure–activity relationships of Ssp1 and, by comparison, of related effectors. Functional assays also reveal that neutralization of these effectors by their cognate immunity proteins, which are called resistance-associated proteins (Raps), contributes an essential role to cell fitness. The structures of two immunity proteins, Rap1a and Rap2a, responsible for the neutralization of Ssp1 and Ssp2-like endopeptidases, respectively, revealed two distinct folds, with that of Rap1a not having previously been observed. The structure of the Ssp1–Rap1a complex revealed a tightly bound heteromeric assembly with two effector molecules flanking a Rap1a dimer. A highly effective steric block of the Ssp1 active site forms the basis of effector neutralization. Comparisons with Ssp2–Rap2a orthologues suggest that the specificity of these immunity proteins for neutralizing effectors is fold-dependent and that in cases where the fold is conserved sequence differences contribute to the specificity of effector–immunity protein interactions. PMID

  12. Considering changing temporal structures in the construction of scenario-neutral runoff response surfaces

    NASA Astrophysics Data System (ADS)

    Vormoor, Klaus; Rössler, Ole; Bürger, Gerd; Weingartner, Rolf; Bronstert, Axel

    2016-04-01

    Climate change impact studies are usually based on traditional top-down approaches in which post-processed climate model data serves as input into some kind of impact model. Parallel to these traditional approaches, scenario-neutral bottom-up approaches have been developed as an alternative methodology which assesses the intrinsic vulnerability of a system towards climate change. Such bottom-approaches perform a sensitivity analysis of an impact model towards systematically 'user-defined' changes in the climate system and summarize its response in a two-dimensional matrix: the response surface. The climate change signal is obtained by perturbing observed time series, which serve as inputs into the impact models. The impact model is then run with all possible combinations of perturbed input data series and the result of each combination (i.e. the impact) is plotted as one single realization (i.e. one pixel) of possible climate change impacts over the two dimensional domain. Although the complexity of existing perturbation methods varies, the temporal structure (i.e. the seasonal- and day-to-day-variability) of these time series often remains the same, which is critical, in particular for the simulations of extremes. In this study, we present standardized response surfaces (SRS) that are based on impact simulations using both perturbed climate observations and projections which are scaled to a common domain. We apply this approach within the field of hydrology and estimate different aspects of runoff response, covering mean runoff as well as extremes like low flows and floods in a Nordic catchment with a mixed snowmelt/rainfall regime. Climate observations and projections from eight GCM-RCM combinations, downscaled by two different methods, are used for the perturbation which results in 17 different SRS. A series of linear regression- and linear mixed-effects models is applied to quantify the different effects of perturbing the climate input data and of the varying

  13. The Structure of the Solar Wind at Large Heliocentric Distances: CIRs and their Successors

    NASA Technical Reports Server (NTRS)

    Gazis, P. R.

    1997-01-01

    Co-rotating interaction regions (CIRs) and their associated shock pairs are dominant structures in the solar wind between the heliocentric distances of 2 and 8 AU. At larger heliocentric distances, these structures undergo a qualitative change. Shocks decay to a point where they are often difficult to detect, and may have little influence on the dynamics of the solar wind. Interaction regions spread and merge, though they appear to retain their identity to surprisingly large distances from the Sun. Solar wind and IMF data from the Pioneer 10, Pioneer 11, and Voyager 2 spacecraft were used to conduct a comprehensive survey of CIRs and their successors between heliocentric distances of 1 and 55 AU over the last two solar cycles. The structure of the solar wind varied in a consistent fashion with heliocentric distance. Similar structures were observed at similar heliocentric distances by all three spacecraft during different portions of the solar cycle.

  14. The Structure of the Solar Wind at Large Heliocentric Distances: CIRs and their Successors

    NASA Technical Reports Server (NTRS)

    Gazis, P. R.

    1999-01-01

    Co-rotating interaction regions (CIRs) and their associated shock pairs are dominant structures in the solar wind between the heliocentric distances of 2 and 8 AU. At larger heliocentric distances, these structures undergo a qualitative change. Shocks decay to a point where they are often difficult to detect, and may have little influence on the dynamics of the solar wind. Interaction regions spread and merge, though they appear to retain their identity to surprisingly large distances from the Sun. Solar wind and IMF data from the Pioneer 10, Pioneer 11, and Voyager 2 spacecraft were used to conduct a comprehensive survey of CIRs and their successors between heliocentric distances of 1 and 55 AU over the last two solar cycles. The structure of the solar wind varied in a consistent fashion with heliocentric distance. Similar structures were observed at similar heliocentric distances by all three spacecraft during different portions of the solar cycle.

  15. Interplanetary shock waves and the structure of solar wind disturbances

    NASA Technical Reports Server (NTRS)

    Hundhausen, A. J.

    1972-01-01

    Observations and theoretical models of interplanetary shock waves are reviewed, with emphasis on the large-scale characteristics of the associated solar wind disturbances and on the relationship of these disturbances to solar activity. The sum of observational knowledge indicates that shock waves propagate through the solar wind along a broad, roughly spherical front, ahead of plasma and magnetic field ejected from solar flares. Typically, the shock front reaches 1 AU about two days after its flare origin, and is of intermediate strength. Not all large flares produce observable interplanetary shock waves; the best indicator of shock production appears to be the generation of both type 2 and type 4 radio bursts by a flare. Theoretical models of shock propagation in the solar wind can account for the typically observed shock strength, transit time, and shape.

  16. Observations of the structure and development of nocturnal slope winds

    SciTech Connect

    Horst, T.W.; Doran, J.C.

    1981-06-01

    This paper presents the slope flow data at an intermediate stage of analysis. Work is continuing on both the Cobb Mountain and Rattlesnake data. The Unit 19 data will be compared to the less-detailed wind and temperature data from other locations in order to obtain a more general picture of both the slope flow and the resulting drainage flow during the 1980 Geysers field study. In addition, during the summer of 1981 new data are being collected at the Rattlesnake site with an expanded array of instrumentation, including both wind and temperature profiles at site A and a fast-response anemometer for detailed turbulence measurements at site B.

  17. Wavelet analysis of the structure of microstreams in the polar solar wind

    SciTech Connect

    Neugebauer, M.; Ruzmaikin, A.; McComas, D.J.

    1997-01-01

    The fluctuations in solar-wind velocity measured by the Ulysses spacecraft above the polar regions of the Sun are organized into structures called microstreams. The application of wavelet transformations to the Ulysses data reveals the scales and positions of the microstreams and their association with variations in the helium content of the solar wind. It is concluded that the microstreams must have their origin in solar structures associated with the acceleration of the solar wind with little modification resulting from interplanetary phenomena. {copyright} {ital 1997 American Institute of Physics.}

  18. Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose

    PubMed Central

    Stanfield, Robyn L; De Castro, Cristina; Marzaioli, Alberto M; Wilson, Ian A; Pantophlet, Ralph

    2015-01-01

    Human immunodeficiency virus-1 (HIV-1) is a major public health threat that continues to infect millions of people worldwide each year. A prophylactic vaccine remains the most cost-effective way of globally reducing and eliminating the spread of the virus. The HIV envelope spike, which is the target of many vaccine design efforts, is densely mantled with carbohydrate and several potent broadly neutralizing antibodies to HIV-1 recognize carbohydrate on the envelope spike as a major part of their epitope. However, immunizing with recombinant forms of the envelope glycoprotein does not typically elicit anti-carbohydrate antibodies. Thus, studies of alternative antigens that may serve as a starting point for carbohydrate-based immunogens are of interest. Here, we present the crystal structure of one such anti-carbohydrate HIV neutralizing antibody (2G12) in complex with the carbohydrate backbone of the lipooligosaccharide from Rhizobium radiobacter strain Rv3, which exhibits a chemical structure that naturally mimics the core high-mannose carbohydrate epitope of 2G12 on HIV-1 gp120. The structure described here provides molecular evidence of the structural homology between the Rv3 oligosaccharide and highly abundant carbohydrates on the surface of HIV-1 and raises the potential for the design of novel glycoconjugates that may find utility in efforts to develop immunogens for eliciting carbohydrate-specific neutralizing antibodies to HIV. PMID:25380763

  19. Demonstration of structural optimization applied to wind-tunnel model design

    NASA Astrophysics Data System (ADS)

    French, Mark; Kolonay, Raymond M.

    1992-10-01

    Results are presented which indicate that using structural optimization to design wind-tunnel models can result in a procedure that matches design stiffnesses well enough to be very useful in sizing the structures of aeroelastic models. The design procedure that is presented demonstrates that optimization can be useful in the design of aeroelastically scaled wind-tunnel models. The resulting structure effectively models an aeroelastically tailored composite wing with a simple aluminum beam structure, a structure that should be inexpensive to manufacture compared with a composite one.

  20. Line profiles variations from atmospheric eclipses: Constraints on the wind structure in Wolf-Rayet stars

    NASA Technical Reports Server (NTRS)

    Auer, L. H.; Koenigsberger, G.

    1994-01-01

    Binary systems in which one of the components has a stellar wind may present a phenomenon known as 'wind' or 'atmospheric eclipse', in which that wind occults the luminous disk of the companion. The enhanced absorption profile, relative to the spectrum at uneclipsed orbital phases, can be be modeled to yield constraints on the spatial structure of the eclipsing wind. A new, very efficient approach to the radiative transfer problem, which makes no requirements with respect to monotonicity of the velocity gradient or size of that gradient, is presented. The technique recovers both the comoving frame calculation and the Sobolev approximation in the appropiate limits. Sample computer simulations of the line profile variations induced by wind eclipses are presented. It is shown that the location of the wind absorption features in frequency is a diagnostic tool for identifying the size of the wind acceleration region. Comparison of the model profile variations with the observed variations in the Wolf-Rayet (W-R)+6 binary system V444 Cyg illustrate how the method can be used to derive information on the structure of the wind of the W-R star constrain the size of the W-R core radius.

  1. Wind turbine control systems: Dynamic model development using system identification and the fast structural dynamics code

    SciTech Connect

    Stuart, J.G.; Wright, A.D.; Butterfield, C.P.

    1996-10-01

    Mitigating the effects of damaging wind turbine loads and responses extends the lifetime of the turbine and, consequently, reduces the associated Cost of Energy (COE). Active control of aerodynamic devices is one option for achieving wind turbine load mitigation. Generally speaking, control system design and analysis requires a reasonable dynamic model of {open_quotes}plant,{close_quotes} (i.e., the system being controlled). This paper extends the wind turbine aileron control research, previously conducted at the National Wind Technology Center (NWTC), by presenting a more detailed development of the wind turbine dynamic model. In prior research, active aileron control designs were implemented in an existing wind turbine structural dynamics code, FAST (Fatigue, Aerodynamics, Structures, and Turbulence). In this paper, the FAST code is used, in conjunction with system identification, to generate a wind turbine dynamic model for use in active aileron control system design. The FAST code is described and an overview of the system identification technique is presented. An aileron control case study is used to demonstrate this modeling technique. The results of the case study are then used to propose ideas for generalizing this technique for creating dynamic models for other wind turbine control applications.

  2. Aspects of structural health and condition monitoring of offshore wind turbines

    PubMed Central

    Antoniadou, I.; Dervilis, N.; Papatheou, E.; Maguire, A. E.; Worden, K.

    2015-01-01

    Wind power has expanded significantly over the past years, although reliability of wind turbine systems, especially of offshore wind turbines, has been many times unsatisfactory in the past. Wind turbine failures are equivalent to crucial financial losses. Therefore, creating and applying strategies that improve the reliability of their components is important for a successful implementation of such systems. Structural health monitoring (SHM) addresses these problems through the monitoring of parameters indicative of the state of the structure examined. Condition monitoring (CM), on the other hand, can be seen as a specialized area of the SHM community that aims at damage detection of, particularly, rotating machinery. The paper is divided into two parts: in the first part, advanced signal processing and machine learning methods are discussed for SHM and CM on wind turbine gearbox and blade damage detection examples. In the second part, an initial exploration of supervisor control and data acquisition systems data of an offshore wind farm is presented, and data-driven approaches are proposed for detecting abnormal behaviour of wind turbines. It is shown that the advanced signal processing methods discussed are effective and that it is important to adopt these SHM strategies in the wind energy sector. PMID:25583864

  3. Aspects of structural health and condition monitoring of offshore wind turbines.

    PubMed

    Antoniadou, I; Dervilis, N; Papatheou, E; Maguire, A E; Worden, K

    2015-02-28

    Wind power has expanded significantly over the past years, although reliability of wind turbine systems, especially of offshore wind turbines, has been many times unsatisfactory in the past. Wind turbine failures are equivalent to crucial financial losses. Therefore, creating and applying strategies that improve the reliability of their components is important for a successful implementation of such systems. Structural health monitoring (SHM) addresses these problems through the monitoring of parameters indicative of the state of the structure examined. Condition monitoring (CM), on the other hand, can be seen as a specialized area of the SHM community that aims at damage detection of, particularly, rotating machinery. The paper is divided into two parts: in the first part, advanced signal processing and machine learning methods are discussed for SHM and CM on wind turbine gearbox and blade damage detection examples. In the second part, an initial exploration of supervisor control and data acquisition systems data of an offshore wind farm is presented, and data-driven approaches are proposed for detecting abnormal behaviour of wind turbines. It is shown that the advanced signal processing methods discussed are effective and that it is important to adopt these SHM strategies in the wind energy sector. PMID:25583864

  4. Neutral hydrogen shell structure near Comet P/Halley deduced from Vega-1 and Giotto energetic particle data

    NASA Astrophysics Data System (ADS)

    Verigin, M. I.; McKenna-Lawlor, S.; Richter, A. K.; Szego, K.; Veselovskii, I. S.

    An existing model based on Vega-1 (Tunde-M) and Giotto (EPONA) energetic particle data, representing neutral gas shells expanding about Comet Halley, has been updated by incorporating additional information concerning energetic particles recorded by Tunde-M, and neutral gas measurements recorded aboard the Vega-1 and Vega-2 spacecraft, in the original data set. The modified model reproduces reasonably well the positions of the maxima in the intensity profiles of energetic cometary ions observed along the Vega and Giotto trajectories, and it is estimated that the velocity of gas in the envisioned neutral shells is about 7.3 km/s, i.e., close to the velocity (about 8 km/s) of the slow hydrogen component of cometary neutrals. Detailed arguments are presented to support the suggestion that, at distances of 2-10 x exp 6 km from the comet nucleus, the energetic particles recorded in the quasi-periodic structures identified by the Tunde-M and EPONA instruments were protons.

  5. Two cases of convecting structure in the slow solar wind turbulence

    NASA Astrophysics Data System (ADS)

    Tu, Chuanyi; Wang, Xin; He, Jiansen; Marsch, Eckart; Wang, Linghua

    2016-03-01

    The slow solar wind turbulence has recently been considered as fully evolved turbulence which can be described by critical balance theory. However, here we present two cases of convecting structure that support a different understanding. By using the measurements from WIND spacecraft in the slow solar wind, we find that Elsässer variables Z± of these two cases do not represent inward and outward Alfvén waves, but are determined mainly by the magnetic variations, including tangentially varying structures. We then propose that the slow wind turbulence may be composed of convecting magnetic-field tangential and directional turnings, as well as current sheets, which may be considered as left-over fossils from Kolmogorov fluid turbulence. The fluid kinetic energy has been damped out, and the remaining magnetic fluctuations thus tend to become force-free structures.

  6. The structure and strength of public attitudes towards wind farm development

    NASA Astrophysics Data System (ADS)

    Bidwell, David Charles

    A growing social science literature seeks to understand why, despite broad public support for wind energy, proposals for specific projects are often met with strong local opposition. This gap between general and specific attitudes is viewed as a significant obstacle to the deployment of wind energy technologies. This dissertation applies theoretical perspectives and methodological tools from social psychology to provide insights on the structure and strength of attitudes towards the potential development of commercial wind farm in three coastal areas of Michigan. A survey of attitudes was completed by 375 residents in these communities and structural equation modeling was used to explore the relationship among variables. The analysis found that attitudes towards wind farm development are shaped by anticipated economic benefits to the community, but expectations of economic benefit are driven by personal values. Social psychology has long recognized that all attitudes are not created equal. Weak attitudes are fleeting and prone to change, while strong attitudes are stable over time and resistant to change. There are two fundamental paths to strong attitudes: repeated experience with an attitude object or the application of deeply held principles or values to that object. Structural equation models were also used to understand the strength of attitudes among the survey respondents. Both the anticipated effects of wind farm development and personal values were found to influence the strength of attitudes towards wind farms. However, while expectations that wind farm development will have positive effects on the economy bolster two measures of attitude strength (collective identity and importance), these expectations are associated with a decline in a third measure (confidence). A follow-up survey asking identical questions was completed by completed by 187 respondents to the initial survey. Linear regressions models were used to determine the effects of attitude

  7. Modified Adaptive Control for Region 3 Operation in the Presence of Wind Turbine Structural Modes

    NASA Technical Reports Server (NTRS)

    Frost, Susan Alane; Balas, Mark J.; Wright, Alan D.

    2010-01-01

    Many challenges exist for the operation of wind turbines in an efficient manner that is reliable and avoids component fatigue and failure. Turbines operate in highly turbulent environments resulting in aerodynamic loads that can easily excite turbine structural modes, possibly causing component fatigue and failure. Wind turbine manufacturers are highly motivated to reduce component fatigue and failure that can lead to loss of revenue due to turbine down time and maintenance costs. The trend in wind turbine design is toward larger, more flexible turbines that are ideally suited to adaptive control methods due to the complexity and expense required to create accurate models of their dynamic characteristics. In this paper, we design an adaptive collective pitch controller for a high-fidelity simulation of a utility-scale, variable-speed horizontal axis wind turbine operating in Region 3. The objective of the adaptive pitch controller is to regulate generator speed, accommodate wind gusts, and reduce the excitation of structural modes in the wind turbine. The control objective is accomplished by collectively pitching the turbine blades. The adaptive collective pitch controller for Region 3 was compared in simulations with a baseline classical Proportional Integrator (PI) collective pitch controller. The adaptive controller will demonstrate the ability to regulate generator speed in Region 3, while accommodating gusts, and reducing the excitation of certain structural modes in the wind turbine.

  8. Fading Coronal Structure and the Onset of Turbulence in the Young Solar Wind

    NASA Astrophysics Data System (ADS)

    DeForest, C. E.; Matthaeus, W. H.; Viall, N. M.; Cranmer, S. R.

    2016-09-01

    Above the top of the solar corona, the young, slow solar wind transitions from low-β, magnetically structured flow dominated by radial structures to high-β, less structured flow dominated by hydrodynamics. This transition, long inferred via theory, is readily apparent in the sky region close to 10° from the Sun in processed, background-subtracted solar wind images. We present image sequences collected by the inner Heliospheric Imager instrument on board the Solar-Terrestrial Relations Observatory (STEREO/HI1) in 2008 December, covering apparent distances from approximately 4° to 24° from the center of the Sun and spanning this transition in the large-scale morphology of the wind. We describe the observation and novel techniques to extract evolving image structure from the images, and we use those data and techniques to present and quantify the clear textural shift in the apparent structure of the corona and solar wind in this altitude range. We demonstrate that the change in apparent texture is due both to anomalous fading of the radial striae that characterize the corona and to anomalous relative brightening of locally dense puffs of solar wind that we term “flocculae.” We show that these phenomena are inconsistent with smooth radial flow, but consistent with the onset of hydrodynamic or magnetohydrodynamic instabilities leading to a turbulent cascade in the young solar wind.

  9. Wind effects on the lateral structure of density-driven circulation in Chesapeake Bay

    NASA Astrophysics Data System (ADS)

    Guo, Xinyu; Valle-Levinson, Arnoldo

    2008-10-01

    The response of the density-driven circulation in the Chesapeake Bay to wind forcing was studied with numerical experiments. A model of the bay with realistic bathymetry was first applied to produce the density-driven flow under average river discharge and tidal forcing. Subsequently, four spatially uniform wind fields (northeasterly, northwesterly, southwesterly, and southeasterly) were imposed to examine the resulting cross-estuary structure of salinity and flow fields. In general, northeasterly and northwesterly winds intensified the density-driven circulation in the upper and middle reaches of the bay, whereas southeasterly and southwesterly winds weakened it. The response was different in the lower bay, where downwind flow from the upper and middle reaches of the bay competed with onshore/offshore coastal flows. Wind remote effects were dominant, over local effects, on volume transports through the bay entrance. However, local effects were more influential in establishing the sea-level slopes that drove subtidal flows and salinity fields in most of the bay. The effect of vertical stratification on wind-induced flows was also investigated by switching it off. The absence of stratification allowed development of Ekman layers that reached depths of the same order as the water depth. Consequently, bathymetric effects became influential on the homogeneous flow structure causing the wind-induced flow inside the bay to show a marked transverse structure: downwind over the shallow areas and upwind in the channels. In the presence of stratification, Ekman layers became shallower and the wind-induced currents showed weaker transverse structure than those that developed in the absence of stratification. In essence, the wind-driven flows were horizontally sheared under weak stratification and vertically sheared under stratified conditions.

  10. Structure-Function Analysis of the Epitope for 4E10, a Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody†

    PubMed Central

    Brunel, Florence M.; Zwick, Michael B.; Cardoso, Rosa M. F.; Nelson, Josh D.; Wilson, Ian A.; Burton, Dennis R.; Dawson, Philip E.

    2006-01-01

    The human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 4E10 binds to a linear, highly conserved epitope within the membrane-proximal external region of the HIV-1 envelope glycoprotein gp41. We have delineated the peptide epitope of the broadly neutralizing 4E10 antibody to gp41 residues 671 to 683, using peptides with different lengths encompassing the previously suggested core epitope (NWFDIT). Peptide binding to the 4E10 antibody was assessed by competition enzyme-linked immunosorbent assay, and the Kd values of selected peptides were determined using surface plasmon resonance. An Ala scan of the epitope indicated that several residues, W672, F673, and T676, are essential (>1,000-fold decrease in binding upon replacement with alanine) for 4E10 recognition. In addition, five other residues, N671, D674, I675, W680, and L679, make significant contributions to 4E10 binding. In general, the Ala scan results agree well with the recently reported crystal structure of 4E10 in complex with a 13-mer peptide and with our circular dichroism analyses. Neutralization competition assays confirmed that the peptide NWFDITNWLWYIKKKK-NH2 could effectively inhibit 4E10 neutralization. Finally, to limit the conformational flexibility of the peptides, helix-promoting 2-aminoisobutyric acid residues and helix-inducing tethers were incorporated. Several peptides have significantly improved affinity (>1,000-fold) over the starting peptide and, when used as immunogens, may be more likely to elicit 4E10-like neutralizing antibodies. Hence, this study represents the first stage toward iterative development of a vaccine based on the 4E10 epitope. PMID:16439525

  11. Identification of minute damage in composite bridge structures equipped with fiber optic sensors using the location of neutral axis and finite element analysis

    NASA Astrophysics Data System (ADS)

    Li, Xi; Glisic, Branko

    2016-04-01

    By definition, the neutral axis of a loaded composite beam structure is the curve along which the section experiences zero bending strain. When no axial loading is present, the location of the neutral axis passes through the centroid of stiffness of the beam cross-section. In the presence of damage, the centroid of stiffness, as well as the neutral axis, shift from the healthy position. The concept of neutral axis can be widely applied to all beam-like structures. According to literature, a change in location of the neutral axis can be associated with damage in the corresponding cross-section. In this paper, the movement of neutral axis near locations of minute damage in a composite bridge structure was studied using finite element analysis and experimental results. The finite element model was developed based on a physical scale model of a composite simply-supported structure with controlled minute damage in the reinforced concrete deck. The structure was equipped with long-gauge fiber optic strain and temperature sensors at a healthy reference location as well as two locations of damage. A total of 12 strain sensors were installed during construction and used to monitor the structure during various loading events. This paper aims to explain previous experimental results which showed that the observed positions of neutral axis near damage locations were higher than the predicted healthy locations in some loading events. Analysis has shown that finite element analysis has potential to simulate and explain the physical behavior of the test structure.

  12. Coronal sources of the intrastream structure of the solar wind

    NASA Technical Reports Server (NTRS)

    Sullivan, J. D.; Bridge, H. S.

    1983-01-01

    Short time scale changes in the bulk speed were found not to coincide with X-ray transients near the sub-earth point nor with the number of X-ray bright points within a coronal hole and near the equator. The changes in bulk speed, it is shown, are associated with changes in light areas in a hole which may be associated with the opening or closing of magnetic field lines within the coronal hole. That there is a causal connection between these sudden changes (apperance or disappearance) in light area and sudden changes in the bulk speed of the solar wind is further evidenced by the spatial proximity on the Sun of these changing light regions to the source position of stream lines from Levine's model that connect into the same solar wind streams.

  13. Model structure of a cosmic-ray mediated stellar or solar wind

    NASA Technical Reports Server (NTRS)

    Lee, M. A.; Axford, W. I.

    1988-01-01

    An idealized hydrodynamic model is presented for the mediation of a free-streaming stellar wind by galactic cosmic rays or energetic particles accelerated at the stellar wind termination shock. The spherically-symmetric stellar wind is taken to be cold; the only body force is the cosmic ray pressure gradient. The cosmic rays are treated as a massless fluid with an effective mean diffusion coefficient k proportional to radial distance r. The structure of the governing equations is investigated both analytically and numerically. Solutions for a range of values of k are presented which describe the deceleration of the stellar wind and a transition to nearly incompressible flow and constant cosmic ray pressure at large r. In the limit of small k the transition steepens to a strong stellar wind termination shock. For large k the stellar wind is decelerated gradually with no shock transition. It is argued that the solutions provide a simple model for the mediation of the solar wind by interstellar ions as both pickup ions and the cosmic ray anomalous component which together dominate the pressure of the solar wind at large r.

  14. A computational model for the rise and dispersion of wind-blown, buoyancy-driven plumes—I. Neutrally stratified atmosphere

    NASA Astrophysics Data System (ADS)

    Zhang, Xiaoming; Ghoniem, Ahmed F.

    A multi-dimensional computational model for the rise and dispersion of a wind-blown, buoyancy-driven plume in a calm, neutrally stratified atmosphere is presented. Lagrangian numerical techniques, based on the extension of the vortex method to variable density flows, are used to solve the governing equations. The plume rise trajectory and the dispersion of its material in the crosswind plane are predicted. It is found that the computed trajectory agrees well with the two-thirds power law of a buoyancy-dominated plume, modified to include the effect of the initial plume size. The effect of small-scale atmospheric turbulence, modeled in terms of eddy viscosity, on the plume trajectory is found to be negligible. For all values of buoyancy Reynolds number, the plume cross-section exhibits a kidney-shaped pattern, as observed in laboratory and field experiments. This pattern is due to the formation of two counter-rotating vortices which develop as baroclinically generated vorticity rolls up on both sides of the plume cross-section. Results show that the plume rise can be described in terms of three distinct stages: a short acceleration stage, a long double-vortex stage, and a breakup stage. The induced velocity field and engulfment are dominated by the two large vortices. The effect of a flat terrain on the plume trajectory and dispersion is found to be very small. The equivalent radii of plumes with different initial cross-sectional aspect ratios increase at almost the same rate. A large aspect-ratio plume rises slower initially and then catches up with smaller aspect-ratio plumes in the breakup stage. The Boussinesq approximation is found to be valid if the ratio of the density perturation to the reference density is less than 0.1.

  15. Plasma beta control of scaling of solar wind turbulent structures

    NASA Astrophysics Data System (ADS)

    Safrankova, Jana; Nemecek, Zdenek; Nemec, Frantisek; Prech, Lubomir; Chen, Christopher H. K.; Zastenker, Georgy N.

    2016-04-01

    The high-time resolution of Spektr-R plasma measurements allows us to make direct observations of solar wind turbulence below ion kinetic length scales. The paper analyzes solar wind power spectra of bulk and thermal speeds that are computed with a time resolution of 32 ms in the frequency range of 0.001-2 Hz. The statistics based on more than 5000 of individual spectra shows that: (1) the spectra of bulk and thermal speeds can be fitted by two power-law segments; (2) despite their large variations, the parameters characterizing frequency spectra fits computed on each particular time interval are very similar for both quantities; (3) the median slopes of the segment attributed to the MHD scale are ‑1.43 and ‑1.38, respectively for the bulk and thermal speeds, whereas those in the kinetic scale are ‑3.08 and ‑2.43, respectively; (4) the break between both MHD and kinetic scales is controlled the ion beta; and (5) the power index corresponding to kinetic turbulence depends on a level of the density variations in the high beta solar wind, whereas the ion gyromotion determines it for low beta intervals.

  16. The effects of vortex structure and vortex translation on the tropical cyclone boundary layer wind field

    NASA Astrophysics Data System (ADS)

    Williams, Gabriel J.

    2015-03-01

    The effects of vortex translation and radial vortex structure in the distribution of boundary layer winds in the inner core of mature tropical cyclones are examined using a high-resolution slab model and a multilevel model. It is shown that the structure and magnitude of the wind field (and the corresponding secondary circulation) depends sensitively on the radial gradient of the gradient wind field above the boundary layer. Furthermore, it is shown that vortex translation creates low wave number asymmetries in the wind field that rotate anticyclonically with height. A budget analysis of the steady state wind field for both models was also performed in this study. Although the agradient force drives the evolution of the boundary layer wind field for both models, it is shown that the manner in which the boundary layer flow responds to this force differs between the two model representations. In particular, the inner core boundary layer flow in the slab model is dominated by the effects of horizontal advection and horizontal diffusion, leading to the development of shock structures in the model. Conversely, the inner core boundary layer flow in the multilevel model is primarily influenced by the effects of vertical advection and vertical diffusion, which eliminates shock structures in this model. These results further indicate that special care is required to ensure that qualitative applications from slab models are not unduly affected by the neglect of vertical advection. This article was corrected on 31 MAR 2015. See the end of the full text for details.

  17. Cellular porous anodic alumina grown in neutral organic electrolyte. 1. Structure, composition, and properties of the films

    SciTech Connect

    Liu, Y.; Alwitt, R.S.; Shimizu, K.

    2000-04-01

    Anodic alumina films with cellular porous structure grow in neutral organic electrolytes with low water content and containing ethylene glycol and a large dicarboxylic acid. An Al carboxylate precipitates in the pore and is extruded from the coating. The porous structure develops even though the current efficiency for film formation is near 95%. The coating matrix contains substantial organic material, 15 wt % by thermal analysis. It is an oxide/organic composite with higher field strength and lower dielectric constant than pure anodic alumina.

  18. Solar wind and coronal structure near sunspot minimum - Pioneer and SMM observations from 1985-1987

    NASA Technical Reports Server (NTRS)

    Mihalov, J. D.; Barnes, A.; Hundhausen, A. J.; Smith, E. J.

    1990-01-01

    Changes in solar wind speed and magnetic polarity observed at the Pioneer spacecraft are discussed here in terms of the changing magnetic geometry implied by SMM coronagraph observations over the period 1985-1987. The pattern of recurrent solar wind streams, the long-term average speed, and the sector polarity of the interplanetary magnetic field all changed in a manner suggesting both a temporal variation, and a changing dependence on heliographic latitude. Coronal observations during this epoch show a systematic variation in coronal structure and the magnetic structure imposed on the expanding solar wind. These observations suggest interpretation of the solar wind speed variations in terms of the familiar model where the speed increases with distance from a nearly flat interplanetary current sheet, and where this current sheet becomes aligned with the solar equatorial plane as sunspot minimum approaches, but deviates rapidly from that orientation after minimum.

  19. STEREO's in-situ perspective on the solar minimum solar wind structure

    NASA Astrophysics Data System (ADS)

    Luhmann, J. G.; Larson, D.; Schroeder, P.; Lee, C. O.; Sauvaud, J.; Acuna, M. H.; Galvin, A. B.; Russell, C. T.; Jian, L.; Arge, C. N.; Odstrcil, D.; Riley, P.; Howard, R. A.; Aschwanden, M.; MacNeice, P.; Chulaki, A.

    2007-05-01

    STEREO multipoint measurements of the solar wind structure with the IMPACT and PLASTIC investigations, near Earth but off the Sun-Earth line, allow its sources and structure to be examined at solar minimum when such studies are particularly straightforward. With the aid of 3D models of the heliosphere available at the CCMC, we map the in-situ observations to their solar sources using a combination of the open field regions inferred from the SECCHI EUVI imagers and SOHO EIT, and the magnetogram-based models of the corona and solar wind. Our ultimate goal is the continuous tracking of solar wind source regions as the STEREO mission progresses, as well as the use of the mappings to deduce the distinctive properties of solar wind from different types of sources

  20. An acoustic-array based structural health monitoring technique for wind turbine blades

    NASA Astrophysics Data System (ADS)

    Aizawa, Kai; Poozesh, Peyman; Niezrecki, Christopher; Baqersad, Javad; Inalpolat, Murat; Heilmann, Gunnar

    2015-04-01

    This paper proposes a non-contact measurement technique for health monitoring of wind turbine blades using acoustic beamforming techniques. The technique works by mounting an audio speaker inside a wind turbine blade and observing the sound radiated from the blade to identify damage within the structure. The main hypothesis for the structural damage detection is that the structural damage (cracks, edge splits, holes etc.) on the surface of a composite wind turbine blade results in changes in the sound radiation characteristics of the structure. Preliminary measurements were carried out on two separate test specimens, namely a composite box and a section of a wind turbine blade to validate the methodology. The rectangular shaped composite box and the turbine blade contained holes with different dimensions and line cracks. An acoustic microphone array with 62 microphones was used to measure the sound radiation from both structures when the speaker was located inside the box and also inside the blade segment. A phased array beamforming technique and CLEAN-based subtraction of point spread function from a reference (CLSPR) were employed to locate the different damage types on both the composite box and the wind turbine blade. The same experiment was repeated by using a commercially available 48-channel acoustic ring array to compare the test results. It was shown that both the acoustic beamforming and the CLSPR techniques can be used to identify the damage in the test structures with sufficiently high fidelity.

  1. Structural basis for type VI secreted peptidoglycan dl-endopeptidase function, specificity and neutralization in Serratia marcescens

    SciTech Connect

    Srikannathasan, Velupillai; English, Grant; Bui, Nhat Khai; Trunk, Katharina; O’Rourke, Patrick E. F.; Rao, Vincenzo A.; Vollmer, Waldemar; Coulthurst, Sarah J. Hunter, William N.

    2013-12-01

    Crystal structures of type VI secretion system-associated immunity proteins, a peptidoglycan endopeptidase and a complex of the endopeptidase and its cognate immunity protein are reported together with assays of endopeptidase activity and functional assessment. Some Gram-negative bacteria target their competitors by exploiting the type VI secretion system to extrude toxic effector proteins. To prevent self-harm, these bacteria also produce highly specific immunity proteins that neutralize these antagonistic effectors. Here, the peptidoglycan endopeptidase specificity of two type VI secretion-system-associated effectors from Serratia marcescens is characterized. These small secreted proteins, Ssp1 and Ssp2, cleave between γ-d-glutamic acid and l-meso-diaminopimelic acid with different specificities. Ssp2 degrades the acceptor part of cross-linked tetratetrapeptides. Ssp1 displays greater promiscuity and cleaves monomeric tripeptides, tetrapeptides and pentapeptides and dimeric tetratetra and tetrapenta muropeptides on both the acceptor and donor strands. Functional assays confirm the identity of a catalytic cysteine in these endopeptidases and crystal structures provide information on the structure–activity relationships of Ssp1 and, by comparison, of related effectors. Functional assays also reveal that neutralization of these effectors by their cognate immunity proteins, which are called resistance-associated proteins (Raps), contributes an essential role to cell fitness. The structures of two immunity proteins, Rap1a and Rap2a, responsible for the neutralization of Ssp1 and Ssp2-like endopeptidases, respectively, revealed two distinct folds, with that of Rap1a not having previously been observed. The structure of the Ssp1–Rap1a complex revealed a tightly bound heteromeric assembly with two effector molecules flanking a Rap1a dimer. A highly effective steric block of the Ssp1 active site forms the basis of effector neutralization. Comparisons with Ssp2–Rap2

  2. High-R Walls for New Construction Structural Performance: Wind Pressure Testing

    SciTech Connect

    DeRenzis, A.; Kochkin, V.

    2013-01-01

    This technical report is focused primarily on laboratory testing that evaluates wind pressure performance characteristics for wall systems constructed with exterior insulating sheathing. This research and test activity will help to facilitate the ongoing use of non-structural sheathing options and provide a more in-depth understanding of how wall system layers perform in response to high wind perturbations normal to the surface.

  3. High-R Walls for New Construction Structural Performance. Wind Pressure Testing

    SciTech Connect

    DeRenzis, A.; Kochkin, V.

    2013-01-01

    This technical report is focused primarily on laboratory testing that evaluates wind pressure performance characteristics for wall systems constructed with exterior insulating sheathing. This research and test activity will help to facilitate the ongoing use of non-structural sheathing options and provide a more in-depth understanding of how wall system layers perform in response to high wind perturbations normal to the surface.

  4. Structural Studies of Chikungunya Virus-Like Particles Complexed with Human Antibodies: Neutralization and Cell-to-Cell Transmission

    PubMed Central

    Mangala Prasad, Vidya; Wang, Cheng-I; Akahata, Wataru; Ng, Lisa F. P.

    2015-01-01

    ABSTRACT Chikungunya virus is a positive-stranded RNA alphavirus. Structures of chikungunya virus-like particles in complex with strongly neutralizing antibody Fab fragments (8B10 and 5F10) were determined using cryo-electron microscopy and X-ray crystallography. By fitting the crystallographically determined structures of these Fab fragments into the cryo-electron density maps, we show that Fab fragments of antibody 8B10 extend radially from the viral surface and block receptor binding on the E2 glycoprotein. In contrast, Fab fragments of antibody 5F10 bind the tip of the E2 B domain and lie tangentially on the viral surface. Fab 5F10 fixes the B domain rigidly to the surface of the virus, blocking exposure of the fusion loop on glycoprotein E1 and therefore preventing the virus from becoming fusogenic. Although Fab 5F10 can neutralize the wild-type virus, it can also bind to a mutant virus without inhibiting fusion or attachment. Although the mutant virus is no longer able to propagate by extracellular budding, it can, however, enter the next cell by traveling through junctional complexes without being intercepted by a neutralizing antibody to the wild-type virus, thus clarifying how cell-to-cell transmission can occur. IMPORTANCE Alphaviral infections are transmitted mainly by mosquitoes. Chikungunya virus (CHIKV), which belongs to the Alphavirus genus, has a wide distribution in the Old World that has expanded in recent years into the Americas. There are currently no vaccines or drugs against alphaviral infections. Therefore, a better understanding of CHIKV and its associated neutralizing antibodies will aid in the development of effective treatments. PMID:26537684

  5. Multiple Eyewall Structure and its Wind Features in 2012 Typhoon Bolaven

    NASA Astrophysics Data System (ADS)

    Origuchi, S.

    2015-12-01

    Typhoon 'Bolaven' passed the Okinawa Main Island at about 1200 UTC 26 August 2012, while moving northwestward. The radar images showed that 'Bolaven' had the multiple eyewall structure. The surface observation data at Nago of Okinawa showed that the precipitation and surface wind velocity in the typhoon's central region were weaker than those of the Japan Meteorological Agency (JMA)'s operational forecast. Cloud-resolving ensemble simulations were performed to investigate the relations between the multiple eyewall structure and the wind features in the typhoon's central regions. The ensemble simulations reproduced double eyewall structures in several members. To evaluate the reproducibility of multiple eyewall structures, the multi-eye index (MEI) was defined in this study. Compared with the members in which the typhoon had the spiral rainband structures, the pressure gradients in the typhoon's central region of the small MEI (multiple eyewall) members were weak. The precipitation and surface wind velocity were also weaker than those of the typhoons with spiral rainbands. In case of the multiple eyewall typhoon, the gentle pressure gradients and the associated weaker surface inflows suppressed convections in the inner eyewall. The statistical analysis was performed based on the ensemble prediction. A clear positive correlation was indicated between the MEI and the wind velocity (tangential wind and inward radial wind) in the typhoon's central region. This result explains the reason why the actual wind velocity was weaker than that of the original JMA's forecast. The relationship between the atmospheric environmental factors around the typhoon (e.g., level of free convection and convective available potential energy) and MEI was investigated from the outputs of ensemble simulations. The results indicated that there were no strong relations between them. This suggests that the formation of the multiple eyewall structures is not simply determined by the atmospheric

  6. Characteristics of surface wind structure of tropical cyclones over the north Indian Ocean

    NASA Astrophysics Data System (ADS)

    Mohapatra, M.; Sharma, Monica

    2015-10-01

    Tropical cyclone (TC) wind field monitoring and forecast are important for mariners, ships on sea and modelling group for creation of synthetic vortex, and storm surge and coastal inundation forecasting. Among others, a multi-platform satellite surface wind analysis developed by Co-operative Institute for Research in the Atmosphere (CIRA), USA for the TCs are referred by India Meteorological Department for surface wind field monitoring of TC. Hence, a study has been undertaken to analyze the characteristics of surface wind distribution and hence the structure of TC based on the real time data available from CIRA during 2007-2013. The study includes 19 TCs over the Bay of Bengal (BOB) and six over Arabian Sea (AS). The maximum radial extent of winds reaching threshold values of 34(17), 50(26) and 64(33) knot (ms-1) in each of the four geographical quadrants has been segregated with respect to season of formation, basin of formation and intensity of TC for analysis. The objective is to develop a reference surface wind structure of TC and examine its validity with respect to physical processes. The size of outer core (34(17) knot (ms-1) wind radial extension) as well as inner core (50(26) and 64(33) knot (ms-1) wind radial extension) increases significantly with increase in intensification of TC over BOB during both pre-monsoon and post-monsoon seasons and over AS during pre-monsoon season. The outer core of winds in TCs over the BOB is asymmetric in both pre-monsoon and post-monsoon seasons and for all categories of intensity of TCs. On the other hand, the asymmetry in inner core winds is significantly less. There is also no asymmetry in radial wind extension over the AS during both the seasons, except in case of outer core wind radial extension of VSCS during pre-monsoon season. The low level environment like enhanced cross equatorial flow, lower/middle level relative humidity, vertical wind shear and proximity of TC to the land surface are the determining factors

  7. Structural Health Monitoring challenges on the 10-MW offshore wind turbine model

    NASA Astrophysics Data System (ADS)

    Di Lorenzo, E.; Kosova, G.; Musella, U.; Manzato, S.; Peeters, B.; Marulo, F.; Desmet, W.

    2015-07-01

    The real-time structural damage detection on large slender structures has one of its main application on offshore Horizontal Axis Wind Turbines (HAWT). The renewable energy market is continuously pushing the wind turbine sizes and performances. This is the reason why nowadays offshore wind turbines concepts are going toward a 10 MW reference wind turbine model. The aim of the work is to perform operational analyses on the 10-MW reference wind turbine finite element model using an aeroelastic code in order to obtain long-time-low- cost simulations. The aeroelastic code allows simulating the damages in several ways: by reducing the edgewise/flapwise blades stiffness, by adding lumped masses or considering a progressive mass addiction (i.e. ice on the blades). The damage detection is then performed by means of Operational Modal Analysis (OMA) techniques. Virtual accelerometers are placed in order to simulate real measurements and to estimate the modal parameters. The feasibility of a robust damage detection on the model has been performed on the HAWT model in parked conditions. The situation is much more complicated in case of operating wind turbines because the time periodicity of the structure need to be taken into account. Several algorithms have been implemented and tested in the simulation environment. They are needed in order to carry on a damage detection simulation campaign and develop a feasible real-time damage detection method. In addition to these algorithms, harmonic removal tools are needed in order to dispose of the harmonics due to the rotation.

  8. Flow around new wind fence with multi-scale fractal structure in an atmospheric boundary layer

    NASA Astrophysics Data System (ADS)

    McClure, Sarah; Lee, Sang-Joon; Zhang, Wei

    2015-11-01

    Understanding and controlling atmospheric boundary-layer flows with engineered structures, such as porous wind fences or windbreaks, has been of great interest to the fluid mechanics and wind engineering community. Previous studies found that the regular mono-scale grid fence of 50% porosity and a bottom gap of 10% of the fence height are considered to be optimal over a flat surface. Significant differences in turbulent flow structure have recently been noted behind multi-scale fractal wind fences, even with the same porosity. In this study, wind-tunnel tests on the turbulent flow and the turbulence kinetic energy transport of 1D and 2D multi-scale fractal fences under atmospheric boundary-layer were conducted. Velocity fields around the fractal fences were systematically measured using Particle Image Velocimetry to uncover effects of key parameters on turbulent flows around the fences at a Reynolds number of approximately 3.6x104 based on the free-stream speed and fence height. The turbulent flow structures induced by specific 1D/2D multi-scale fractal wind fences were compared to those of a conventional grid fence. The present results would contribute to the design of new-generation wind fences to reduce snow/sand deposition on critical infrastructure such as roads and bridges.

  9. Augmented Adaptive Control of a Wind Turbine in the Presence of Structural Modes

    NASA Technical Reports Server (NTRS)

    Frost, Susan A.; Balas, Mark J.; Wright, Alan D.

    2010-01-01

    Wind turbines operate in highly turbulent environments resulting in aerodynamic loads that can easily excite turbine structural modes, potentially causing component fatigue and failure. Two key technology drivers for turbine manufacturers are increasing turbine up time and reducing maintenance costs. Since the trend in wind turbine design is towards larger, more flexible turbines with lower frequency structural modes, manufacturers will want to develop methods to operate in the presence of these modes. Accurate models of the dynamic characteristics of new wind turbines are often not available due to the complexity and expense of the modeling task, making wind turbines ideally suited to adaptive control. In this paper, we develop theory for adaptive control with rejection of disturbances in the presence of modes that inhibit the controller. We use this method to design an adaptive collective pitch controller for a high-fidelity simulation of a utility-scale, variable-speed wind turbine operating in Region 3. The objective of the adaptive pitch controller is to regulate generator speed, accommodate wind gusts, and reduce the interference of certain structural modes in feedback. The control objective is accomplished by collectively pitching the turbine blades. The adaptive pitch controller for Region 3 is compared in simulations with a baseline classical Proportional Integrator (PI) collective pitch controller.

  10. Advanced system identification techniques for wind turbine structures with special emphasis on modal parameters

    SciTech Connect

    Bialasiewicz, J.T.

    1995-06-01

    The goal of this research is to develop advanced system identification techniques that can be used to accurately measure the frequency response functions of a wind-turbine structure immersed in wind noise. To allow for accurate identification, the authors have developed a special test signal called the Pseudo-Random Binary Sequence (PRBS). The Matlab program that generates this signal allows the user to interactively tailor its parameters for the frequency range of interest based on the response of the wind turbine under test. By controlling NREL`s Mobile Hydraulic Shaker System, which is attached to the wind turbine structure, the PRBS signal produces the wide-band excitation necessary to perform system identification in the presence of wind noise. The techniques presented here will enable researchers to obtain modal parameters from an operating wind turbine, including frequencies, damping coefficients, and mode shapes. More importantly, the algorithms they have developed and tested (so far using input-output data from a simulated structure) permit state-space representation of the system under test, particularly the modal state space representation. This is the only system description that reveals the internal behavior the system, such as the interaction between the physical parameters, and which, in contrast to transfer functions, is valid for non-zero initial conditions.

  11. Approximate method for calculating free vibrations of a large-wind-turbine tower structure

    NASA Technical Reports Server (NTRS)

    Das, S. C.; Linscott, B. S.

    1977-01-01

    A set of ordinary differential equations were derived for a simplified structural dynamic lumped-mass model of a typical large-wind-turbine tower structure. Dunkerley's equation was used to arrive at a solution for the fundamental natural frequencies of the tower in bending and torsion. The ERDA-NASA 100-kW wind turbine tower structure was modeled, and the fundamental frequencies were determined by the simplified method described. The approximate fundamental natural frequencies for the tower agree within 18 percent with test data and predictions analyzed.

  12. Modal testing of a very flexible 110 m wind turbine structure

    SciTech Connect

    Carne, T.G.; Lauffer, J.P.; Gomez, A.J.; Benjannet, Hassine

    1988-01-01

    Modal Testing of immense and very flexible structures poses a number of problems. It requires innovative excitation techniques since the modal frequencies of these stuctures can be quite low. Also, substantial energy must be input to the structure to obtain reasonable levels of response. In this paper, results are presented from a modal test of the 110 m tall EOLE wind turbine which had four modal frequencies below 1.0 Hz. Step-relaxation and wind were used to excite the structure. 5 refs., 14 figs., 2 tabs.

  13. Wind-tunnel measurements in the wakes of structures

    NASA Technical Reports Server (NTRS)

    Woo, H. G. C.; Peterka, J. A.; Cermak, J. E.

    1977-01-01

    Detailed measurements of longitudinal mean velocity, turbulence intensity, space correlations, and spectra made in the wake of two rectangular scaled models in simulated atmospheric boundary-layer winds are presented. The model buildings were 1:50 scale models of two trailers. Results of a flow visualization study of the wake geometry are analyzed with some singular point theorems. Two hypothetical flow patterns of the detailed wake geometry are proposed. Some preliminary studies of the vortex wake, effects of the model size, model aspect ratios, and boundary layer characteristics on the decay rate and extent of the wake are also presented and discussed.

  14. THE SPATIALLY RESOLVED H{alpha}-EMITTING WIND STRUCTURE OF P CYGNI

    SciTech Connect

    Balan, Aurelian; Tycner, C.; Zavala, R. T.; Benson, J. A.; Hutter, D. J.; Templeton, M. E-mail: c.tycner@cmich.ed E-mail: jbenson@nofs.navy.mi E-mail: matthewt@aavso.or

    2010-06-15

    High spatial resolution observations of the H{alpha}-emitting wind structure associated with the luminous blue variable star P Cygni were obtained with the Navy Prototype Optical Interferometer. These observations represent the most comprehensive interferometric data set on P Cyg to date. We demonstrate how the apparent size of the H{alpha}-emitting region of the wind structure of P Cyg compares between the 2005, 2007, and 2008 observing seasons and how this relates to the H{alpha} line spectroscopy. Using the data sets from 2005, 2007, and 2008 observing seasons, we fit a circularly symmetric Gaussian model to the interferometric signature from the H{alpha}-emitting wind structure of P Cyg. Based on our results, we conclude that the radial extent of the H{alpha}-emitting wind structure around P Cyg is stable at the 10% level. We also show how the radial distribution of the H{alpha} flux from the wind structure deviates from a Gaussian shape, whereas a two-component Gaussian model is sufficient to fully describe the H{alpha}-emitting region around P Cyg.

  15. Examining Periodic Solar-Wind Density Structures Observed in the SECCHI Heliospheric Imagers

    NASA Technical Reports Server (NTRS)

    Viall, Nicholeen M.; Spence, Harlan E.; Vourlidas, Angelos; Howard, Russell

    2010-01-01

    We present an analysis of small-scale, periodic, solar-wind density enhancements (length scales as small as approximately equals 1000 Mm) observed in images from the Heliospheric Imager (HI) aboard STEREO-A. We discuss their possible relationship to periodic fluctuations of the proton density that have been identified at 1 AU using in-situ plasma measurements. Specifically, Viall, Kepko, and Spence examined 11 years of in-situ solar-wind density measurements at 1 AU and demonstrated that not only turbulent structures, but also nonturbulent, periodic density structures exist in the solar wind with scale sizes of hundreds to one thousand Mm. In a subsequent paper, Viall, Spence, and Kasper analyzed the alpha-to-proton solar-wind abundance ratio measured during one such event of periodic density structures, demonstrating that the plasma behavior was highly suggestive that either temporally or spatially varying coronal source plasma created those density structures. Large periodic density structures observed at 1 AU, which were generated in the corona, can be observable in coronal and heliospheric white-light images if they possess sufficiently high density contrast. Indeed, we identify such periodic density structures as they enter the HI field of view and follow them as they advect with the solar wind through the images. The smaller, periodic density structures that we identify in the images are comparable in size to the larger structures analyzed in-situ at 1 AU, yielding further evidence that periodic density enhancements are a consequence of coronal activity as the solar wind is formed.

  16. Structures in the polar solar wind: Plasma and field observations from Ulysses

    SciTech Connect

    McComas, D.J.; Barraclough, B.L.; Gosling, J.T.; Hammond, C.M.; Phillips, J.L.; Neugebauer, M.; Balogh, A.; Forsyth, R.J.

    1996-07-01

    The Ulysses measurements of the solar wind plasma and magnetic fields for the 36-69 deg.south latitude are analyzed. The plasma compressional structures and pressure balance structures are identified in addition to Alfven waves and coronal mass ejection. {copyright} {bold 1997 American Institute of Physics.}

  17. Density functional study of carbon clusters C2n (2<=n<=16). I. Structure and bonding in the neutral clusters

    NASA Astrophysics Data System (ADS)

    Jones, R. O.

    1999-03-01

    Density functional calculations have been performed for many isomers of neutral carbon clusters Cn (4⩽n⩽32, n even) using both local spin density (LSD) and gradient-corrected (Becke-Perdew) approximations to the exchange-correlation energy. The stable isomers include chains, rings, cages, and graphitic ("plate " and "bowl") structures, and we observe a fourfold periodicity in several structural classes as n changes. Stable cages exist for all clusters with n⩾8, and double rings are less stable than the monocyclic rings in all cases. Most planar structures have low-frequency out-of-plane vibrations. Gradient corrections often change the ordering of the energies of the isomers, but the effects are remarkably regular within a given structural type.

  18. Structural Basis of Neutralization by a Human Anti-severe Acute Respiratory Syndrome Spike Protein Antibody,80R.

    SciTech Connect

    Hwang,W.; Lin, Y.; Santelli, E.; Sui, J.; Jaroszewski, L.; Stec, B.; Farzan, M.; Marasco, W.; Liddington, R.

    2006-01-01

    Severe acute respiratory syndrome (SARS) is a newly emerged infectious disease that caused pandemic spread in 2003. The etiological agent of SARS is a novel coronavirus (SARS-CoV). The coronaviral surface spike protein S is a type I transmembrane glycoprotein that mediates initial host binding via the cell surface receptor angiotensin-converting enzyme 2 (ACE2), as well as the subsequent membrane fusion events required for cell entry. Here we report the crystal structure of the S1 receptor binding domain (RBD) in complex with a neutralizing antibody, 80R, at 2.3 {angstrom} resolution, as well as the structure of the uncomplexed S1 RBD at 2.2 {angstrom} resolution. We show that the 80R-binding epitope on the S1 RBD overlaps very closely with the ACE2-binding site, providing a rationale for the strong binding and broad neutralizing ability of the antibody. We provide a structural basis for the differential effects of certain mutations in the spike protein on 80R versus ACE2 binding, including escape mutants, which should facilitate the design of immunotherapeutics to treat a future SARS outbreak. We further show that the RBD of S1 forms dimers via an extensive interface that is disrupted in receptor- and antibody-bound crystal structures, and we propose a role for the dimer in virus stability and infectivity.

  19. 3D printing meets computational astrophysics: deciphering the structure of η Carinae's inner colliding winds

    NASA Astrophysics Data System (ADS)

    Madura, T. I.; Clementel, N.; Gull, T. R.; Kruip, C. J. H.; Paardekooper, J.-P.

    2015-06-01

    We present the first 3D prints of output from a supercomputer simulation of a complex astrophysical system, the colliding stellar winds in the massive (≳120 M⊙), highly eccentric (e ˜ 0.9) binary star system η Carinae. We demonstrate the methodology used to incorporate 3D interactive figures into a PDF (Portable Document Format) journal publication and the benefits of using 3D visualization and 3D printing as tools to analyse data from multidimensional numerical simulations. Using a consumer-grade 3D printer (MakerBot Replicator 2X), we successfully printed 3D smoothed particle hydrodynamics simulations of η Carinae's inner (r ˜ 110 au) wind-wind collision interface at multiple orbital phases. The 3D prints and visualizations reveal important, previously unknown `finger-like' structures at orbital phases shortly after periastron (φ ˜ 1.045) that protrude radially outwards from the spiral wind-wind collision region. We speculate that these fingers are related to instabilities (e.g. thin-shell, Rayleigh-Taylor) that arise at the interface between the radiatively cooled layer of dense post-shock primary-star wind and the fast (3000 km s-1), adiabatic post-shock companion-star wind. The success of our work and easy identification of previously unrecognized physical features highlight the important role 3D printing and interactive graphics can play in the visualization and understanding of complex 3D time-dependent numerical simulations of astrophysical phenomena.

  20. Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27

    PubMed Central

    Yu, Xiaojuan; Zhang, Senyan; Jiang, Liwei; Cui, Ye; Li, Dongxia; Wang, Dongli; Wang, Nianshuang; Fu, Lili; Shi, Xuanlin; Li, Ziqiang; Zhang, Linqi; Wang, Xinquan

    2015-01-01

    The recently reported Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe respiratory illness in humans with an approximately 30% mortality rate. The envelope spike glycoprotein on the surface of MERS-CoV mediates receptor binding, membrane fusion, and viral entry. We previously reported two human monoclonal antibodies that target the receptor binding domain (RBD) of the spike and exhibit strong neutralization activity against live and pesudotyped MERS-CoV infection. Here we determined the crystal structure of MERS-CoV RBD bound to the Fab fragment of MERS-27 antibody at 3.20 Å resolution. The MERS-27 epitope in the RBD overlaps with the binding site of the MERS-CoV receptor DPP4. Further biochemical, viral entry, and neutralization analyses identified two critical residues in the RBD for both MERS-27 recognition and DPP4 binding. One of the residues, Trp535, was found to function as an anchor residue at the binding interface with MERS-27. Upon receptor binding, Trp535 interacts with the N-linked carbohydrate moiety of DPP4. Thus, MERS-27 inhibits MERS-CoV infection by directly blocking both protein-protein and protein-carbohydrate interactions between MERS-CoV RBD and DPP4. These results shed light on the molecular basis of MERS-27 neutralization and will assist in the optimization of MERS-27 as a tool to combat MERS-CoV infection. PMID:26281793

  1. Models of Solar Wind Structures and Their Interaction with the Earth's Space Environment

    NASA Astrophysics Data System (ADS)

    Watermann, J.; Wintoft, P.; Sanahuja, B.; Saiz, E.; Poedts, S.; Palmroth, M.; Milillo, A.; Metallinou, F.-A.; Jacobs, C.; Ganushkina, N. Y.; Daglis, I. A.; Cid, C.; Cerrato, Y.; Balasis, G.; Aylward, A. D.; Aran, A.

    2009-11-01

    The discipline of “Space Weather” is built on the scientific foundation of solar-terrestrial physics but with a strong orientation toward applied research. Models describing the solar-terrestrial environment are therefore at the heart of this discipline, for both physical understanding of the processes involved and establishing predictive capabilities of the consequences of these processes. Depending on the requirements, purely physical models, semi-empirical or empirical models are considered to be the most appropriate. This review focuses on the interaction of solar wind disturbances with geospace. We cover interplanetary space, the Earth’s magnetosphere (with the exception of radiation belt physics), the ionosphere (with the exception of radio science), the neutral atmosphere and the ground (via electromagnetic induction fields). Space weather relevant state-of-the-art physical and semi-empirical models of the various regions are reviewed. They include models for interplanetary space, its quiet state and the evolution of recurrent and transient solar perturbations (corotating interaction regions, coronal mass ejections, their interplanetary remnants, and solar energetic particle fluxes). Models of coupled large-scale solar wind-magnetosphere-ionosphere processes (global magnetohydrodynamic descriptions) and of inner magnetosphere processes (ring current dynamics) are discussed. Achievements in modeling the coupling between magnetospheric processes and the neutral and ionized upper and middle atmospheres are described. Finally we mention efforts to compile comprehensive and flexible models from selections of existing modules applicable to particular regions and conditions in interplanetary space and geospace.

  2. NREL Wind Turbine Blade Structural Testing of the Modular Wind Energy MW45 Blade: Cooperative Research and Development Final Report, CRADA Number CRD-09-354

    SciTech Connect

    Hughes, S.

    2012-05-01

    This CRADA was a purely funds-in CRADA with Modular Wind Energy (MWE). MWE had a need to perform full-scale testing of a 45-m wind turbine blade. NREL/NWTC provided the capabilities, facilities, and equipment to test this large-scale MWE wind turbine blade. Full-scale testing is required to demonstrate the ability of the wind turbine blade to withstand static design load cases and demonstrate the fatigue durability. Structural testing is also necessary to meet international blade testing certification requirements. Through this CRADA, MWE would obtain test results necessary for product development and certification, and NREL would benefit by working with an industrial partner to better understand the unique test requirements for wind turbine blades with advanced structural designs.

  3. Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer

    PubMed Central

    Matho, Michael H.; Schlossman, Andrew; Meng, Xiangzhi; Benhnia, Mohammed Rafii-El-Idrissi; Kaever, Thomas; Buller, Mark; Doronin, Konstantin; Parker, Scott; Peters, Bjoern; Crotty, Shane; Xiang, Yan; Zajonc, Dirk M.

    2015-01-01

    Vaccinia virus A33 is an extracellular enveloped virus (EEV)-specific type II membrane glycoprotein that is essential for efficient EEV formation and long-range viral spread within the host. A33 is a target for neutralizing antibody responses against EEV. In this study, we produced seven murine anti-A33 monoclonal antibodies (MAbs) by immunizing mice with live VACV, followed by boosting with the soluble A33 homodimeric ectodomain. Five A33 specific MAbs were capable of neutralizing EEV in the presence of complement. All MAbs bind to conformational epitopes on A33 but not to linear peptides. To identify the epitopes, we have adetermined the crystal structures of three representative neutralizing MAbs in complex with A33. We have further determined the binding kinetics for each of the three antibodies to wild-type A33, as well as to engineered A33 that contained single alanine substitutions within the epitopes of the three crystallized antibodies. While the Fab of both MAbs A2C7 and A20G2 binds to a single A33 subunit, the Fab from MAb A27D7 binds to both A33 subunits simultaneously. A27D7 binding is resistant to single alanine substitutions within the A33 epitope. A27D7 also demonstrated high-affinity binding with recombinant A33 protein that mimics other orthopoxvirus strains in the A27D7 epitope, such as ectromelia, monkeypox, and cowpox virus, suggesting that A27D7 is a potent cross-neutralizer. Finally, we confirmed that A27D7 protects mice against a lethal challenge with ectromelia virus. PMID:26325270

  4. Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer.

    PubMed

    Matho, Michael H; Schlossman, Andrew; Meng, Xiangzhi; Benhnia, Mohammed Rafii-El-Idrissi; Kaever, Thomas; Buller, Mark; Doronin, Konstantin; Parker, Scott; Peters, Bjoern; Crotty, Shane; Xiang, Yan; Zajonc, Dirk M

    2015-09-01

    Vaccinia virus A33 is an extracellular enveloped virus (EEV)-specific type II membrane glycoprotein that is essential for efficient EEV formation and long-range viral spread within the host. A33 is a target for neutralizing antibody responses against EEV. In this study, we produced seven murine anti-A33 monoclonal antibodies (MAbs) by immunizing mice with live VACV, followed by boosting with the soluble A33 homodimeric ectodomain. Five A33 specific MAbs were capable of neutralizing EEV in the presence of complement. All MAbs bind to conformational epitopes on A33 but not to linear peptides. To identify the epitopes, we have adetermined the crystal structures of three representative neutralizing MAbs in complex with A33. We have further determined the binding kinetics for each of the three antibodies to wild-type A33, as well as to engineered A33 that contained single alanine substitutions within the epitopes of the three crystallized antibodies. While the Fab of both MAbs A2C7 and A20G2 binds to a single A33 subunit, the Fab from MAb A27D7 binds to both A33 subunits simultaneously. A27D7 binding is resistant to single alanine substitutions within the A33 epitope. A27D7 also demonstrated high-affinity binding with recombinant A33 protein that mimics other orthopoxvirus strains in the A27D7 epitope, such as ectromelia, monkeypox, and cowpox virus, suggesting that A27D7 is a potent cross-neutralizer. Finally, we confirmed that A27D7 protects mice against a lethal challenge with ectromelia virus. PMID:26325270

  5. Magnetic field sector structure and origins of solar wind streams in 2012

    NASA Astrophysics Data System (ADS)

    Shugay, Yulia; Slemzin, Vladimir; Veselovsky, Igor

    2014-08-01

    The origins of the solar wind and the interplanetary magnetic field sector structure in the beginning of the magnetic polarity reversal of 24th solar cycle were investigated using the Wilcox Solar Observatory magnetic field measurements and their products as well as the solar wind data from ACE and the SDO/AIA EUV images. The dominance of the quadrupole harmonics in the solar magnetic field in this period resulted in a four-sector structure of the interplanetary magnetic field. The dominating source of recurrent high-speed solar wind stream was a large trans-equatorial coronal hole of negative polarity evolving in the course of the polarity reversal process. The contribution of ICMEs to the high-speed solar wind did not exceed 17% of the total flux. The solar wind density flux averaged over the year amounted to 1 × 108 cm-2 s-1 which is considerably lower than the typical long-term value (2-4 × 108 cm-2 s-1). The slow-speed component of solar wind density flux constituted in average more than 68% of the total flux, the high-speed component was about 10%, reaching the maximum of 32% in some Carrington rotations.

  6. OBSERVATIONAL EVIDENCE OF A CORONAL MASS EJECTION DISTORTION DIRECTLY ATTRIBUTABLE TO A STRUCTURED SOLAR WIND

    SciTech Connect

    Savani, N. P.; Owens, M. J.; Forsyth, R. J.; Rouillard, A. P.; Davies, J. A.

    2010-05-01

    We present the first observational evidence of the near-Sun distortion of the leading edge of a coronal mass ejection (CME) by the ambient solar wind into a concave structure. On 2007 November 14, a CME was observed by coronagraphs onboard the STEREO-B spacecraft, possessing a circular cross section. Subsequently the CME passed through the field of view of the STEREO-B Heliospheric Imagers where the leading edge was observed to distort into an increasingly concave structure. The CME observations are compared to an analytical flux rope model constrained by a magnetohydrodynamic solar wind solution. The resultant bimodal speed profile is used to kinematically distort a circular structure that replicates the initial shape of the CME. The CME morphology is found to change rapidly over a relatively short distance. This indicates an approximate radial distance in the heliosphere where the solar wind forces begin to dominate over the magnetic forces of the CME influencing the shape of the CME.

  7. Structural design and fabrication of the Sandia 34-meter Vertical Axis Wind Turbine

    SciTech Connect

    Ashwill, T.D.

    1987-01-01

    The Wind Energy Research Division of Sandia National Laboratories has been funded by the Wind/Ocean Technology Division of the Department of Energy (DOE) to design and build a 34-meter diameter Vertical Axis Wind Turbine (VAWT). The turbine design incorporates the results of recent VAWT research in aerodynamics and structural dynamics. Initial system concept studies identified several blade options that met the required power rating of 500 kW. The final blade and rotor configurations were chosen based on finite element calculations that determined the turbine modes of response, their frequency of vibration, and stress levels. For parked survival turbine components were designed to with stand the loading of a 150 mph (67.0 m/s) wind coupled with maximum cable tensions. Specific areas of design discussed include the rotor, cables, bearings, brakes, and foundations. Construction of the turbine is in progress at this time and anticipated completion of the project is late spring of 1987.

  8. Structural basis for the binding of the neutralizing antibody, 7D11, to the poxvirus L1 protein

    SciTech Connect

    Su, Hua-Poo; Golden, Joseph W.; Gittis, Apostolos G.; Hooper, Jay W.; Garboczi, David N.

    2007-11-25

    Medical countermeasures to prevent or treat smallpox are needed due to the potential use of poxviruses as biological weapons. Safety concerns with the currently available smallpox vaccine indicate a need for research on alternative poxvirus vaccine strategies. Molecular vaccines involving the use of proteins and/or genes and recombinant antibodies are among the strategies under current investigation. The poxvirus L1 protein, encoded by the L1R open reading frame, is the target of neutralizing antibodies and has been successfully used as a component of both protein subunit and DNA vaccines. L1-specific monoclonal antibodies (e.g., mouse monoclonal antibody mAb-7D11, mAb-10F5) with potent neutralizing activity bind L1 in a conformation-specific manner. This suggests that proper folding of the L1 protein used in molecular vaccines will affect the production of neutralizing antibodies and protection. Here, we co-crystallized the Fab fragment of mAb-7D11 with the L1 protein. The crystal structure of the complex between Fab-7D11 and L1 reveals the basis for the conformation-specific binding as recognition of a discontinuous epitope containing two loops that are held together by a disulfide bond. The structure of this important conformational epitope of L1 will contribute to the development of molecular poxvirus vaccines and also provides a novel target for anti-poxvirus drugs. In addition, the sequence and structure of Fab-7D11 will contribute to the development of L1-targeted immunotherapeutics.

  9. Neutralizer optimization

    NASA Technical Reports Server (NTRS)

    Patterson, Michael J.; Mohajeri, Kayhan

    1991-01-01

    The preliminary results of a test program to optimize a neutralizer design for 30 cm xenon ion thrusters are discussed. The impact of neutralizer geometry, neutralizer axial location, and local magnetic fields on neutralizer performance is discussed. The effect of neutralizer performance on overall thruster performance is quantified, for thruster operation in the 0.5-3.2 kW power range. Additionally, these data are compared to data published for other north-south stationkeeping (NSSK) and primary propulsion xenon ion thruster neutralizers.

  10. The Structure of Magnetocentrifugal Jets and Winds I. Steady Mass Loading

    SciTech Connect

    Anderson, J.

    2004-12-15

    We present the results of a series of time-dependent numerical simulations of cold, magnetocentrifugally launched winds from accretion disks. The goal of this study is to determine how the mass loading from the disk affects the structure and dynamics of the wind for a given distribution of magnetic field. Our simulations span four and half decades of mass loading; in the context of a disk with a launching region from 0.1 AU to 1.0 AU around a 1M{circle_dot} star and a field strength of about 20 G at the inner disk edge, this amounts to mass loss rates of 1 x 10{sup -9} - 3 x 10{sup -5} M{circle_dot} yr{sup -1} from each side of the disk. We find that, as expected intuitively, the degree of collimation of the wind increases with mass loading; however even the ''lightest'' wind simulated is significantly collimated compared with the force-free magnetic configuration of the same magnetic flux distribution at the launching surface, which becomes radial at large distances. The implication is that for flows from young stellar objects a radial field approximation is inappropriate. Surprisingly, the terminal velocity of the wind and the magnetic lever arm are still well-described by the analytical solutions for a radial field geometry. We also find that the isodensity contours and Alfven surface are very nearly self-similar in mass loading. The wind becomes unsteady above some critical mass loading rate. The exact value of the critical rate depends on the (small) velocity with which we inject the material into the wind. For a small enough injection speed, we are able to obtain the first examples of a class of heavily-loaded magnetocentrifugal winds with magnetic fields completely dominated by the toroidal component all the way to the launching surface. The stability of such toroidally dominated winds in 3D will be the subject of a future investigation.

  11. Elastic dynamics of a complete wind turbine structure: Theoretical development

    NASA Astrophysics Data System (ADS)

    Lobitz, D. W.; Arguello, J. G.; Veers, P. S.

    A pseudo-linear formulation of the equations of motion for analyzing elastic bodies which undergo large rotations relative to one another with an emphasis on its application to horizontal axis wind turbines (HAWT) is developed. This procedure greatly simplifies the computational aspects of the solution algorithm over the nonlinear alternatives and should yield a significant improvement in computer speed. Additional speed can be achieved by ordering the nodes such that a minimum bandwidth can be realized (leading to approximately 64 multiplications per degree of freedom per solution step). The formulation utilizes a set of nested moving coordinate systems, each of which is loosely tied to one of the elastic bodies such that the displacements in the body relative to its coordinate system remain small. The formulation also includes a scheme for handling the nonlinear geometric stiffness that occurs in the blades as a result of the centrifugal loads in a pseudo-linear fashion.

  12. Optimization research on the structure of horizontally-arranged indirect air-cooling tower under strong wind condition

    NASA Astrophysics Data System (ADS)

    Chen, Guoyong; Gu, Hongfang; Wang, Haijun; Qin, Yongbo

    2013-07-01

    Strong wind has a significant impact on the heat radiation of the air-cooling system. In this research, a numerical calculation model of 2×1000MW horizontally arranged air-cooling tower is established to simulate the flow distribution and heat exchanging capability of three different structures-horizontally-arranged indirect air-cooling tower, tower with guide wall outside, and tower with a cross wall inside-under high-speed wind and extreme-speed wind conditions. The result reveals that the structure with the guide wall outside the tower only works under strong wind condition while the structure with cross wall inside shows the anti-wind capability under both high-speed wind and extreme-speed wind conditions.

  13. Crystal structure of a 3B3 variant - A broadly neutralizing HIV-1 scFv antibody

    SciTech Connect

    Clark, K. Reed; Walsh, Scott T.R.

    2009-12-10

    We present the crystal structure determination of an anti-HIV-1 gp120 single-chain variable fragment antibody variant, 3B3, at 2.5 {angstrom} resolution. This 3B3 variant was derived from the b12 antibody, using phage display and site-directed mutagenesis of the variable heavy chain (V{sub H}) complementary-determining regions (CDRs). 3B3 exhibits enhanced binding affinity and neutralization activity against several cross-clade primary isolates of HIV-1 by interaction with the recessed CD4-binding site on the gp120 envelope protein. Comparison with the structures of the unbound and bound forms of b12, the 3B3 structure closely resembles these structures with minimal differences with two notable exceptions. First, there is a reorientation of the CDR-H3 of the V{sub H} domain where the primary sequences evolved from b12 to 3B3. The structural changes in CDR-H3 of 3B3, in light of the b12-gp120 complex structure, allow for positioning an additional Trp side chain in the binding interface with gp120. Finally, the second region of structural change involves two peptide bond flips in CDR-L3 of the variable light (VL) domain triggered by a point mutation in CDR-H3 of Q100eY resulting in changes in the intramolecular hydrogen bonding patterning between the VL and VH domains. Thus, the enhanced binding affinities and neutralization capabilities of 3B3 relative to b12 probably result from higher hydrophobic driving potential by burying more aromatic residues at the 3B3-gp120 interface and by indirect stabilization of intramolecular contacts of the core framework residues between the VL and VH domains possibly through more favorable entropic effect through the expulsion of water.

  14. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

    SciTech Connect

    McLellan, Jason S.; Pancera, Marie; Carrico, Chris; Gorman, Jason; Julien, Jean-Philippe; Khayat, Reza; Louder, Robert; Pejchal, Robert; Sastry, Mallika; Dai, Kaifan; O’Dell, Sijy; Patel, Nikita; Shahzad-ul-Hussan, Syed; Yang, Yongping; Zhang, Baoshan; Zhou, Tongqing; Zhu, Jiang; Boyington, Jeffrey C.; Chuang, Gwo-Yu; Diwanji, Devan; Georgiev, Ivelin; Kwon, Young Do; Lee, Doyung; Louder, Mark K.; Moquin, Stephanie; Schmidt, Stephen D.; Yang, Zhi-Yong; Bonsignori, Mattia; Crump, John A.; Kapiga, Saidi H.; Sam, Noel E.; Haynes, Barton F.; Burton, Dennis R.; Koff, Wayne C.; Walker, Laura M.; Phogat, Sanjay; Wyatt, Richard; Orwenyo, Jared; Wang, Lai-Xi; Arthos, James; Bewley, Carole A.; Mascola, John R.; Nabel, Gary J.; Schief, William R.; Ward, Andrew B.; Wilson, Ian A.; Kwong, Peter D.

    2012-12-13

    Variable regions 1 and 2 (V1/V2) of human immunodeficiency virus-1 (HIV-1) gp120 envelope glycoprotein are critical for viral evasion of antibody neutralization, and are themselves protected by extraordinary sequence diversity and N-linked glycosylation. Human antibodies such as PG9 nonetheless engage V1/V2 and neutralize 80% of HIV-1 isolates. Here we report the structure of V1/V2 in complex with PG9. V1/V2 forms a four-stranded {beta}-sheet domain, in which sequence diversity and glycosylation are largely segregated to strand-connecting loops. PG9 recognition involves electrostatic, sequence-independent and glycan interactions: the latter account for over half the interactive surface but are of sufficiently weak affinity to avoid autoreactivity. The structures of V1/V2-directed antibodies CH04 and PGT145 indicate that they share a common mode of glycan penetration by extended anionic loops. In addition to structurally defining V1/V2, the results thus identify a paradigm of antibody recognition for highly glycosylated antigens, which - with PG9 - involves a site of vulnerability comprising just two glycans and a strand.

  15. Structural Characterization of Neutral Oligosaccharides by Laser-Enhanced In-Source Decay of MALDI-FTICR MS

    NASA Astrophysics Data System (ADS)

    Yang, Hongmei; Yu, Yingning; Song, Fengrui; Liu, Shuying

    2011-05-01

    MALDI in-source decay (ISD) technique described to date has proven to be a convenient and rapid method for sequencing purified peptides and proteins. However, the general ISD still can not produce adequate fragments for the detailed structural elucidation of oligosaccharides. In this study, an efficient and practical method termed the laser-enhanced ISD (LEISD) technique of MALDI-FTICR MS allows highly reliable and abundant fragmentation of the neutral oligosaccharides, which was attributed to the ultrahigh irradiation laser of mJ level. The yield of ISD fragmentation was evaluated under different laser powers for 7 neutral oligosaccharides using DHB as matrix. Better quality ISD spectra including fragment ions in low-mass region were obtained at higher laser power. Results from the LEISD of oligosaccharides demonstrated that a significantly better signal-to-noise ratio (S/N) and more structural information could be obtained in comparison to the conventional CID. It was also suggested that the valuable A ions derived from cross-ring cleavage of the linear oligosaccharides allowed the distinction among α(1 → 4)-, α(1 → 6)-, β(1 → 4)-, and β(1 → 3)-linked isobaric structures according to fragment types and intensities. In addition, ideal fragmentation ions observed by LEISD method facilitated the determination of the sequences and branched points of complex oligosaccharides from human milk.

  16. Crystal structure of a human rhinovirus neutralizing antibody complexed with a peptide derived from viral capsid protein VP2.

    PubMed Central

    Tormo, J; Blaas, D; Parry, N R; Rowlands, D; Stuart, D; Fita, I

    1994-01-01

    The three-dimensional structure of the complex between the Fab fragment of an anti-human rhinovirus neutralizing antibody (8F5) and a cross-reactive synthetic peptide from the viral capsid protein VP2 has been determined at 2.5 A resolution by crystallographic methods. The refinement is presently at an R factor of 0.18 and the antigen-binding site and viral peptide are well defined. The peptide antigen adopts a compact fold by two tight turns and interacts through hydrogen bonds, some with ionic character, and van der Waals contacts with antibody residues from the six hypervariable loops as well as several framework amino acids. The conformation adopted by the peptide is closely related to the corresponding region of the viral protein VP2 on the surface of human rhinovirus 1A whose three-dimensional structure is known. Implications for the cross-reactivity between peptides and the viral capsid are discussed. The peptide-antibody interactions, together with the analysis of mutant viruses that escape neutralization by 8F5 suggest two different mechanisms for viral escape. The comparison between the complexed and uncomplexed antibody structures shows important conformational rearrangements, especially in the hypervariable loops of the heavy chain. Thus, it constitutes a clear example of the 'induced fit' molecular recognition mechanism. Images PMID:8194515

  17. Syntheses and structural characterization of mercury (II) coordination polymers with neutral bidentate flexible pyrazole-based ligands

    NASA Astrophysics Data System (ADS)

    Lalegani, Arash; Khaledi Sardashti, Mohammad; Salavati, Hossein; Asadi, Amin; Gajda, Roman; Woźniak, Krzysztof

    2016-03-01

    Mercury(II) coordination compounds [Hg(μ-bbd)(μ-SCN)4]n(1) and [Hg(bpp)(SCN)2] (2) were synthesized by using the neutral flexible bidentate N-donor ligands 1,4-bis(3,5-dimethypyrazol-1-yl)butane (bbd) and 1,3-bis(3,5-dimethylpyrazolyl)propane (bpp), NCS- ligand and appropriate mercury(II) salts. Compound 1 forms a polymeric network with moieties which are connected by SCN groups and the mercury ions present as HgN3S2 trigonal bipyramides. The crystal structure of 2 is build of monomers and the mercury(II) ion adopts an HgN2S2 tetrahedral geometry. In the complex 1, each bbd acts as bridging ligand connecting Hg(μ-SCN)4 ions, while in the complex 2, the bpp ligand is coordinated to an mercury(II) ion in a cyclic-bidentate fashion forming an eight-membered metallocyclic ring. Moreover, in the tetrahedral structure of 2, the neutral molecules form a 1D chain structure through the C-H···N hydrogen bonds, whereas in 1 no hydrogen bonds are observed. Coordination compounds 1 and 2 have been characterized by infrared spectroscopy, elemental analyses and single-crystal X-ray diffraction.

  18. MuD: an interactive web server for the prediction of non-neutral substitutions using protein structural data.

    PubMed

    Wainreb, Gilad; Ashkenazy, Haim; Bromberg, Yana; Starovolsky-Shitrit, Alina; Haliloglu, Turkan; Ruppin, Eytan; Avraham, Karen B; Rost, Burkhard; Ben-Tal, Nir

    2010-07-01

    The discrimination between functionally neutral amino acid substitutions and non-neutral mutations, affecting protein function, is very important for our understanding of diseases. The rapidly growing amounts of experimental data enable the development of computational tools to facilitate the annotation of these substitutions. Here, we describe a Random Forests-based classifier, named Mutation Detector (MuD) that utilizes structural and sequence-derived features to assess the impact of a given substitution on the protein function. In its automatic mode, MuD is comparable to alternative tools in performance. However, the uniqueness of MuD is that user-reported protein-specific structural and functional information can be added at run-time, thereby enhancing the prediction accuracy further. The MuD server, available at http://mud.tau.ac.il, assigns a reliability score to every prediction, thus offering a useful tool for the prioritization of substitutions in proteins with an available 3D structure. PMID:20542913

  19. Density-dependent speciation alters the structure and dynamics of neutral communities.

    PubMed

    Wang, Shaopeng; Chen, Anping; Pacala, Stephen W; Fang, Jingyun

    2015-05-01

    The neutral theory of biodiversity (NTB) provides an individual-based modeling framework to study eco-evolutionary dynamics. Previous NTB models usually assumed the same per capita rate of speciation across lineages. However, population dynamics may induce macroevolutionary feedbacks that can result in variable per capita speciation rates across lineages. In this paper, with analytical and simulation approaches, we explore how different scenarios of density-dependent speciation may impact the diversity and phylogenetic patterns of neutral communities, and compare the results to predictions of the original NTB model with an invariant speciation rate. Our results show that positive per capita speciation rate-abundance relationships could result in higher species richness and evenness, enhanced stability (evidenced by higher post-disturbance recovery rates and lower temporal variability in species diversity), and higher imbalance in phylogenetic trees. The opposite patterns are predicted when per capita speciation rates decrease with abundance. Particularly, strong negative speciation rate-abundance relationships can generate a positive correlation between phylogenetic age and abundance, which has been observed in Panamanian tree species. Our findings demonstrate the importance of eco-evolutionary feedbacks for understanding long-term diversity and phylogenetic patterns in ecological communities. PMID:25701450

  20. Study on steady state wind and turbulence environments. [structure of wakes near buildings

    NASA Technical Reports Server (NTRS)

    Brundidge, K. C.

    1977-01-01

    The structure of wakes and how this structure is related to the size and shape of buildings and other obstacles, and to ambient winds, was investigated. Mean values of natural atmospheric flow were obtained and used in conjunction with theoretical relationships developed by dimensional analysis to establish a model of the flow in the wake. Results indicate that conventional and V/STOL aircraft passing through the wake during takeoff and landing would experience not only a change in turbulence level, but also a change in mean wind speed of a magnitude roughly equivalent to that of the eddy components.

  1. A complete tropical cyclone radial wind structure model and comprehensive comparison with observations

    NASA Astrophysics Data System (ADS)

    Chavas, D. R.; Emanuel, K.; Lin, N.

    2014-12-01

    This work develops a simple model for the complete radial structure of the tropical cyclone wind field at the top of the boundary layer. The model is constructed by mathematically merging existing theoretical solutions for the radial wind structure in the inner convecting and outer non-convecting regions. The model is then evaluated against three observational datasets. First, the outer solution is tested against a global database from the QuikSCAT satellite (1999-2009) and found to reproduce the characteristic wind structure of tropical cyclones at large radii where convection is absent, suggesting that it successfully captures the physics of this region. Second, the inner solution is tested against the HWind database (2004-2012) for the Atlantic and East Pacific basins and are shown to credibly represent the inner-core structure but substantially underestimate wind speeds at large radii. The complete model is then shown to largely rectify this underestimation, particularly at higher intensities. Finally, model variability is compared with the Extended Best Track dataset (1988-2013). The complete model exhibits two modes of variability corresponding to the independent variations in storm size and in inner structure that mirror that observed in nature, including the independent variability of the inner and outer regions of tropical cyclones. More broadly, the model provides insight into clear definitions of the terms "size" and "structure" and their respective, independent variabilities.

  2. OBSERVATIONS OF DETAILED STRUCTURE IN THE SOLAR WIND AT 1 AU WITH STEREO/HI-2

    SciTech Connect

    DeForest, C. E.; Howard, T. A.; Tappin, S. J. E-mail: howard@boulder.swri.edu

    2011-09-01

    We present images of solar wind electron density structures at distances of 1 AU, extracted from the STEREO/HI-2 data. Collecting the images requires separating the Thomson-scattered signal from the other background/foreground sources that are 10{sup 3} times brighter. Using a combination of techniques, we are able to generate calibrated imaging data of the solar wind with sensitivity of a few x 10{sup -17} B{sub sun}, compared to the background signal of a few x 10{sup -13} B{sub sun}, using only the STEREO/HI-2 Level 1 data as input. These images reveal detailed spatial structure in coronal mass ejections (CMEs) and the solar wind at projected solar distances in excess of 1 AU, at the instrumental motion-blur resolution limit of 1{sup 0}-3{sup 0}. CME features visible in the newly reprocessed data from 2008 December include leading-edge pileup, interior voids, filamentary structure, and rear cusps. 'Quiet' solar wind features include V-shaped structures centered on the heliospheric current sheet, plasmoids, and 'puffs' that correspond to the density fluctuations observed in situ. We compare many of these structures with in situ features detected near 1 AU. The reprocessed data demonstrate that it is possible to perform detailed structural analyses of heliospheric features with visible light imagery, at distances from the Sun of at least 1 AU.

  3. The 1.51-Å structure of the poxvirus L1 protein, a target of potent neutralizing antibodies

    PubMed Central

    Su, Hua-Poo; Garman, Scott C.; Allison, Timothy J.; Fogg, Christiana; Moss, Bernard; Garboczi, David N.

    2005-01-01

    Although eradicated from nature more than two decades ago, the threat of smallpox has reemerged because of concerns over its use as a biological weapon. We present the structure of the poxvirus L1 protein, a molecule that is conserved throughout the poxvirus family and is nearly identical in vaccinia virus and in variola virus, which causes smallpox. L1 is a myristoylated envelope protein that is a potent target for neutralizing antibodies and an important component of current experimental vaccines. The L1 structure reveals a hydrophobic cavity located adjacent to its N terminus. The cavity would be capable of shielding the myristate moiety, which is essential for virion assembly. The structure of L1 is a step in the elucidation of molecular mechanisms common to all poxviruses that may stimulate the design of safer vaccines and new antipoxvirus drugs. PMID:15761054

  4. Full-scale tests of wind effects on a long span roof structure

    NASA Astrophysics Data System (ADS)

    Fu, Jiyang; Zheng, Qingxing; Wu, Jiurong; Xu, An

    2015-06-01

    Full-scale measurements are regarded as the most reliable method to evaluate wind effects on large buildings and structures. Some selected results are presented in this paper from the full-scale measurement of wind effects on a long-span steel roof structure during the passage of Typhoon Fanapi. Some field data, including wind speed and direction, acceleration responses, etc., were continuously and simultaneously recorded during the passage of the typhoon. Comprehensive analysis of the measured data is conducted to evaluate the typhoon-generated wind characteristics and its effects on a long-span steel roof. The first four natural frequencies and their vibration mode shapes of the Guangzhou International Sports Arena (GISA) roof are evaluated by the stochastic subspace identification (SSI) method and comparisons with those from finite element (FE) analysis are made. Meanwhile, damping ratios of the roof are also identified by the SSI method and compared with those identified by the random decrement method; the amplitude-dependent damping behaviors are also discussed. The fullscale measurement results are further compared with the corresponding wind tunnel test results to evaluate its reliability. The results obtained from this study are valuable for academic and professional engineers involved in the design of large-span roof structures.

  5. Structural effects of unsteady aerodynamic forces on horizontal-axis wind turbines

    SciTech Connect

    Miller, M.S.; Shipley, D.E.

    1994-08-01

    Due to its renewable nature and abundant resources, wind energy has the potential to fulfill a large portion of this nation`s energy needs. The simplest means of utilizing wind energy is through the use of downwind, horizontal-axis wind turbines (HAWT) with fixed-pitch rotors. This configuration regulates the peak power by allowing the rotor blade to aerodynamically stall. The stall point, the point of maximum coefficient of lift, is currently predicted using data obtained from wind tunnel tests. Unfortunately, these tests do not accurately simulate conditions encountered in the field. Flow around the tower and nacelle coupled with inflow turbulence and rotation of the turbine blades create unpredicted aerodynamic forces. Dynamic stall is hypothesized to occur. Such aerodynamic loads are transmitted into the rotor and tower causing structural resonance that drastically reduces the design lifetime of the wind turbine. The current method of alleviating this problem is to structurally reinforce the tower and blades. However, this adds unneeded mass and, therefore, cost to the turbines. A better understanding of the aerodynamic forces and the manner in which they affect the structure would allow for the design of more cost effective and durable wind turbines. Data compiled by the National Renewable Energy Laboratory (NREL) for a downwind HAWT with constant chord, untwisted, fixed-pitch rotors is analyzed. From these data, the actual aerodynamic characteristics of the rotor are being portrayed and the potential effects upon the structure can for the first time be fully analyzed. Based upon their understanding, solutions to the problem of structural resonance are emerging.

  6. Structural effects of unsteady aerodynamic forces on horizontal-axis wind turbines

    NASA Astrophysics Data System (ADS)

    Miller, M. S.; Shipley, D. E.

    1994-08-01

    Due to its renewable nature and abundant resources, wind energy has the potential to fulfill a large portion of this nation's energy needs. The simplest means of utilizing wind energy is through the use of downwind, horizontal-axis wind turbines (HAWT) with fixed-pitch rotors. This configuration regulates the peak power by allowing the rotor blade to aerodynamically stall. The stall point, the point of maximum coefficient of lift, is currently predicted using data obtained from wind tunnel tests. Unfortunately, these tests do not accurately simulate conditions encountered in the field. Flow around the tower and nacelle coupled with inflow turbulence and rotation of the turbine blades create unpredicted aerodynamic forces. Dynamic stall is hypothesized to occur. Such aerodynamic loads are transmitted into the rotor and tower causing structural resonance that drastically reduces the design lifetime of the wind turbine. The current method of alleviating this problem is to structurally reinforce the tower and blades. However, this adds unneeded mass and, therefore, cost to the turbines. A better understanding of the aerodynamic forces and the manner in which they affect the structure would allow for the design of more cost effective and durable wind turbines. Data compiled by the National Renewable Energy Laboratory (NREL) for a downwind HAWT with constant chord, untwisted, fixed-pitch rotors is analyzed. From these data, the actual aerodynamic characteristics of the rotor are being portrayed and the potential effects upon the structure can for the first time be fully analyzed. Based upon their understanding, solutions to the problem of structural resonance are emerging.

  7. Large fog collectors: New strategies for collection efficiency and structural response to wind pressure

    NASA Astrophysics Data System (ADS)

    Holmes, Robert; Rivera, Juan de Dios; de la Jara, Emilio

    2015-01-01

    Most studies of large fog collectors (LFC) have focused on the collection efficiency, the amount of water collected, or economic and social aspects, but have not addressed the effects of strong winds on the system. Wind pressure is directly related to fog water collection efficiency but on the other hand may cause serious damage on the structure of LFCs. This study focuses in the effects of wind pressure on the components of the LFC as an integral system, and the ways to face strong winds with no significant damage. For this purpose we analysed cases of mechanical failure of LFCs both in our experimental station at Peña Blanca in Chile and elsewhere. The effects of wind pressure can be described as a sequence of physical processes, starting with the mesh deformation as a way of adapting to the induced stresses. For a big enough pressure, local stress concentrations generate a progressive rupture of the mesh. In cases where the mesh is sufficiently strong the wind force causes the partial or total collapse of the structure. Usually the weakest part is the mesh, especially close to where it is attached to the structure. The way the mesh is attached to the frame or cable of the structure is particularly important since it can induce significant stress concentrations. Mesh failure before the structure failure may be considered as a mechanical fuse, since it is cheaper to repair. However, more practical mechanical fuses can be conceived. In relation to structural performance and water collection efficiency, we propose a new design strategy that considers a three-dimensional spatial display of the collection screen, oblique incidence angle of wind on mesh and small mesh area between the supporting frame. The proposed design strategies consider both the wind pressure on mesh and structure and the collection efficiency as an integral solution for the LFC. These new design strategies are the final output of this research. Applying these strategies a multi-funnel LFC is

  8. Structural and molecular basis for Ebola virus neutralization by protective human antibodies.

    PubMed

    Misasi, John; Gilman, Morgan S A; Kanekiyo, Masaru; Gui, Miao; Cagigi, Alberto; Mulangu, Sabue; Corti, Davide; Ledgerwood, Julie E; Lanzavecchia, Antonio; Cunningham, James; Muyembe-Tamfun, Jean Jacques; Baxa, Ulrich; Graham, Barney S; Xiang, Ye; Sullivan, Nancy J; McLellan, Jason S

    2016-03-18

    Ebola virus causes hemorrhagic fever with a high case fatality rate for which there is no approved therapy. Two human monoclonal antibodies, mAb100 and mAb114, in combination, protect nonhuman primates against all signs of Ebola virus disease, including viremia. Here, we demonstrate that mAb100 recognizes the base of the Ebola virus glycoprotein (GP) trimer, occludes access to the cathepsin-cleavage loop, and prevents the proteolytic cleavage of GP that is required for virus entry. We show that mAb114 interacts with the glycan cap and inner chalice of GP, remains associated after proteolytic removal of the glycan cap, and inhibits binding of cleaved GP to its receptor. These results define the basis of neutralization for two protective antibodies and may facilitate development of therapies and vaccines. PMID:26917592

  9. Structure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1.

    PubMed

    Geier, Ethan G; Schlessinger, Avner; Fan, Hao; Gable, Jonathan E; Irwin, John J; Sali, Andrej; Giacomini, Kathleen M

    2013-04-01

    The Large-neutral Amino Acid Transporter 1 (LAT-1)--a sodium-independent exchanger of amino acids, thyroid hormones, and prescription drugs--is highly expressed in the blood-brain barrier and various types of cancer. LAT-1 plays an important role in cancer development as well as in mediating drug and nutrient delivery across the blood-brain barrier, making it a key drug target. Here, we identify four LAT-1 ligands, including one chemically novel substrate, by comparative modeling, virtual screening, and experimental validation. These results may rationalize the enhanced brain permeability of two drugs, including the anticancer agent acivicin. Finally, two of our hits inhibited proliferation of a cancer cell line by distinct mechanisms, providing useful chemical tools to characterize the role of LAT-1 in cancer metabolism. PMID:23509259

  10. Structure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1

    PubMed Central

    Geier, Ethan G.; Schlessinger, Avner; Fan, Hao; Gable, Jonathan E.; Irwin, John J.; Sali, Andrej; Giacomini, Kathleen M.

    2013-01-01

    The Large-neutral Amino Acid Transporter 1 (LAT-1)—a sodium-independent exchanger of amino acids, thyroid hormones, and prescription drugs—is highly expressed in the blood–brain barrier and various types of cancer. LAT-1 plays an important role in cancer development as well as in mediating drug and nutrient delivery across the blood–brain barrier, making it a key drug target. Here, we identify four LAT-1 ligands, including one chemically novel substrate, by comparative modeling, virtual screening, and experimental validation. These results may rationalize the enhanced brain permeability of two drugs, including the anticancer agent acivicin. Finally, two of our hits inhibited proliferation of a cancer cell line by distinct mechanisms, providing useful chemical tools to characterize the role of LAT-1 in cancer metabolism. PMID:23509259

  11. The turbulent structure of katabatic winds in the Spitsbergen coastal zone and energy exchange parameterizations

    NASA Astrophysics Data System (ADS)

    Repina, I.; Kuznetsov, R.; Ivanov, B.

    2009-04-01

    A particularity of the glacier areas is the quasi persistence of strong offshore winds near the surface. The so-called katabatic winds are generated by the negative buoyant force that develops in the stable cooled layer along the ice sheet slopes. Katabatic winds exist in many parts of the world and are winds that flow from the high elevations of mountains, plateaus, and hills down their slopes to the valleys or planes below. They provide the major ventilation mechanism in mountainous regions at night when synoptic pressure gradients are weak. Katabatic winds are the main components of the climate at glaciers and surrounding areas, in particular, at the Antarctica, Greenland, and Arctic islands. Our experiments were carried out near the Kongsvegen glacier in Svalbard during the spring time. Some preliminary observational results from the ground-based measurements during the field experiment in Ny-Alesund at spring time are presented. The predominant flow at Ny-Alesund is from the east-southeast due to katabatic flow from the Kongsvegen glacier 10 km to the east of Ny-Alesund. Neutral conditions were observed from the two predominant wind directions centered in the 120° and 250° sectors. A minor peak with the 20% of unstable cases was observed at 245° while stable conditions were mainly distributed around the sector at 120°. The highest values of the sensible heat fluxes were observed during the day time under forced convection because of the transfer of warmer upper layer air into the surface layer. The dependence of incoming longwave and shortware radiation on cloud amount has been parameterized using relationships reported in the literature. Generally good agreement exists between the measured values and the parameterized those, except the cases of wind blowing from neighboring mountains. For the latent and sensible heat fluxes a new parameterization has been chosen for introducing into the model. The parameterization has been tested for measurement values

  12. Coherent structures and turbulent spectrum in solar wind plasmas

    SciTech Connect

    Sharma, R. P.; Yadav, N.; Kumari, Anju

    2013-08-15

    The present paper investigates the localization of a uniform plane kinetic Alfvén wave (KAW) due to the coupling with the density/magnetic field fluctuations associated with a magnetosonic wave propagating in the transverse direction, i.e., perpendicular to the background magnetic field. To gain the physical insight into this evolution, a simplified analytical model based on the Mathieu equation has also been studied. Numerical method has also been used to analyse the evolution of KAW. The magnetic fluctuation spectrum follows Kolmogorovian scaling above the proton gyroradius scalelength, which is regarded as the inertial range. Below this scale, a steepened spectrum has been obtained in the dispersive range with power law index ∼−2.5, which continues up to the dissipation range. Our results reveal that the proposed mechanism may be an interesting physical mechanism for transferring the energy from larger lengthscales to smaller lengthscales in the solar wind plasmas. Relevance of the present study with Cluster spacecraft observations has also been discussed.

  13. Ascent structural wind loads for the National Space Transportation System (NSTS)

    NASA Technical Reports Server (NTRS)

    Smith, O. E.; Adelfang, S. I.; Brown, R. P.

    1988-01-01

    An aerospace vehicle must withstand the design ascent structural load or be within any flight constraint to safely reach orbit. For the NSTS an assessment for flight readiness is made for each mission. This assessment for ascent loads and performance parameters is stated in terms of launch probability derived from samples of Jimsphere wind profiles. For the day of launch operations an allowance is made for the ascent load variability due to the wind profile variability over a 3.5-hour period. This is the current time period required to obtain a Jimsphere measurement and perform a complete load simulation prior to launch time. The load variability is derived from a sample of 3.5-hour Jimsphere wind profile pairs. It is applied as a conditional percentile value given the wind load at 3.5 hours prior to launch time. Probability models are used for these analyses. Application of the univariate, bivariate and conditional forms of the extreme value (Gumbel) probability distribution to the analysis of extreme wind speeds, wind shears and vehicle loads is described.

  14. Structural damage identification in wind turbine blades using piezoelectric active sensing with ultrasonic validation

    SciTech Connect

    Claytor, Thomas N; Ammerman, Curtt N; Park, Gyu Hae; Farinholt, Kevin M; Farrar, Charles R; Atterbury, Marie K

    2010-01-01

    This paper gives a brief overview of a new project at LANL in structural damage identification for wind turbines. This project makes use of modeling capabilities and sensing technology to understand realistic blade loading on large turbine blades, with the goal of developing the technology needed to automatically detect early damage. Several structural health monitoring (SHM) techniques using piezoelectric active materials are being investigated for the development of wireless, low power sensors that interrogate sections of the wind turbine blade using Lamb wave propagation data, frequency response functions (FRFs), and time-series analysis methods. The modeling and sensor research will be compared with extensive experimental testing, including wind tunnel experiments, load and fatigue tests, and ultrasonic scans - on small- to mid-scale turbine blades. Furthermore, this study will investigate the effect of local damage on the global response of the blade by monitoring low-frequency response changes.

  15. Multi-Scale Structure of Solar Wind Transients Coincident with Electron Drift-Echoes

    NASA Astrophysics Data System (ADS)

    Mulligan, T. L.; O'Brien, T. P., III; Claudepierre, S. G.; Roeder, J. L.; Green, J. C.; Fennell, J. F.

    2014-12-01

    It is well known that impulsive substorm dipolarizations on the night side produce dispersionless injections of keV particles, for which multiple drift echoes can be observed. The impact these injections have on radiation belt particles is less well understood. We present a preliminary investigation into the types of solar wind transients (i.e. coronal mass ejections (CMEs), co-rotational and/or stream interaction regions (CIRs and/or SIRs), high-speed streams (HSS), interplanetary shock events, etc.) that correlate with observations of electron drift echoes during the Van Allen Probes mission. We use data from ACE and Wind during the current solar cycle (24) to establish criteria for determining critical regions and sub-structures within these transients that correlate with observed drift echoes. This initial study is part of a more comprehensive characterization of the multi-scale structure of solar wind drivers coincident with drift echoes through different phases of the solar cycle.

  16. Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity

    PubMed Central

    Long, Feng; Fong, Rachel H.; Austin, Stephen K.; Chen, Zhenguo; Klose, Thomas; Fokine, Andrei; Liu, Yue; Porta, Jason; Sapparapu, Gopal; Akahata, Wataru; Doranz, Benjamin J.; Crowe, James E.; Diamond, Michael S.; Rossmann, Michael G.

    2015-01-01

    Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes severe acute and chronic disease in humans. Although highly inhibitory murine and human monoclonal antibodies (mAbs) have been generated, the structural basis of their neutralizing activity remains poorly characterized. Here, we determined the cryo-EM structures of chikungunya virus-like particles complexed with antibody fragments (Fab) of two highly protective human mAbs, 4J21 and 5M16, that block virus fusion with host membranes. Both mAbs bind primarily to sites within the A and B domains, as well as to the B domain’s β-ribbon connector of the viral glycoprotein E2. The footprints of these antibodies on the viral surface were consistent with results from loss-of-binding studies using an alanine scanning mutagenesis-based epitope mapping approach. The Fab fragments stabilized the position of the B domain relative to the virus, particularly for the complex with 5M16. This finding is consistent with a mechanism of neutralization in which anti-CHIKV mAbs that bridge the A and B domains impede movement of the B domain away from the underlying fusion loop on the E1 glycoprotein and therefore block the requisite pH-dependent fusion of viral and host membranes. PMID:26504196

  17. Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16

    SciTech Connect

    Pancera, Marie; Shahzad-ul-Hussan, Syed; Doria-Rose, Nicole A.; McLellan, Jason S.; Bailer, Robert T.; Dai, Kaifan; Loesgen, Sandra; Louder, Mark K.; Staupe, Ryan P.; Yang, Yongping; Zhang, Baoshan; Parks, Robert; Eudailey, Joshua; Lloyd, Krissey E.; Blinn, Julie; Alam, S. Munir; Haynes, Barton F.; Amin, Mohammed N.; Wang, Lai-Xi; Burton, Dennis R.; Koff, Wayne C.; Nabel, Gary J.; Mascola, John R.; Bewley, Carole A; Kwong, Peter D.

    2013-08-05

    HIV-1 uses a diverse N-linked-glycan shield to evade recognition by antibody. Select human antibodies, such as the clonally related PG9 and PG16, recognize glycopeptide epitopes in the HIV-1 V1–V2 region and penetrate this shield, but their ability to accommodate diverse glycans is unclear. Here we report the structure of antibody PG16 bound to a scaffolded V1–V2, showing an epitope comprising both high mannose–type and complex-type N-linked glycans. We combined structure, NMR and mutagenesis analyses to characterize glycan recognition by PG9 and PG16. Three PG16-specific residues, arginine, serine and histidine (RSH), were critical for binding sialic acid on complex-type glycans, and introduction of these residues into PG9 produced a chimeric antibody with enhanced HIV-1 neutralization. Although HIV-1–glycan diversity facilitates evasion, antibody somatic diversity can overcome this and can provide clues to guide the design of modified antibodies with enhanced neutralization.

  18. Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody.

    PubMed

    Xu, Kai; Rockx, Barry; Xie, Yihu; DeBuysscher, Blair L; Fusco, Deborah L; Zhu, Zhongyu; Chan, Yee-Peng; Xu, Yan; Luu, Truong; Cer, Regina Z; Feldmann, Heinz; Mokashi, Vishwesh; Dimitrov, Dimiter S; Bishop-Lilly, Kimberly A; Broder, Christopher C; Nikolov, Dimitar B

    2013-01-01

    The henipaviruses, represented by Hendra (HeV) and Nipah (NiV) viruses are highly pathogenic zoonotic paramyxoviruses with uniquely broad host tropisms responsible for repeated outbreaks in Australia, Southeast Asia, India and Bangladesh. The high morbidity and mortality rates associated with infection and lack of licensed antiviral therapies make the henipaviruses a potential biological threat to humans and livestock. Henipavirus entry is initiated by the attachment of the G envelope glycoprotein to host cell membrane receptors. Previously, henipavirus-neutralizing human monoclonal antibodies (hmAb) have been isolated using the HeV-G glycoprotein and a human naïve antibody library. One cross-reactive and receptor-blocking hmAb (m102.4) was recently demonstrated to be an effective post-exposure therapy in two animal models of NiV and HeV infection, has been used in several people on a compassionate use basis, and is currently in development for use in humans. Here, we report the crystal structure of the complex of HeV-G with m102.3, an m102.4 derivative, and describe NiV and HeV escape mutants. This structure provides detailed insight into the mechanism of HeV and NiV neutralization by m102.4, and serves as a blueprint for further optimization of m102.4 as a therapeutic agent and for the development of entry inhibitors and vaccines. PMID:24130486

  19. Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.

    PubMed

    Long, Feng; Fong, Rachel H; Austin, Stephen K; Chen, Zhenguo; Klose, Thomas; Fokine, Andrei; Liu, Yue; Porta, Jason; Sapparapu, Gopal; Akahata, Wataru; Doranz, Benjamin J; Crowe, James E; Diamond, Michael S; Rossmann, Michael G

    2015-11-10

    Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes severe acute and chronic disease in humans. Although highly inhibitory murine and human monoclonal antibodies (mAbs) have been generated, the structural basis of their neutralizing activity remains poorly characterized. Here, we determined the cryo-EM structures of chikungunya virus-like particles complexed with antibody fragments (Fab) of two highly protective human mAbs, 4J21 and 5M16, that block virus fusion with host membranes. Both mAbs bind primarily to sites within the A and B domains, as well as to the B domain's β-ribbon connector of the viral glycoprotein E2. The footprints of these antibodies on the viral surface were consistent with results from loss-of-binding studies using an alanine scanning mutagenesis-based epitope mapping approach. The Fab fragments stabilized the position of the B domain relative to the virus, particularly for the complex with 5M16. This finding is consistent with a mechanism of neutralization in which anti-CHIKV mAbs that bridge the A and B domains impede movement of the B domain away from the underlying fusion loop on the E1 glycoprotein and therefore block the requisite pH-dependent fusion of viral and host membranes. PMID:26504196

  20. Damage estimates from long-term structural analysis of a wind turbine in a US wind farm environment

    SciTech Connect

    Kelley, N.D.; Sutherland, H.J.

    1996-10-01

    Time-domain simulations of the loads on wind energy conversion systems have been hampered in the past by the relatively long computational times for nonlinear structural analysis codes. However, recent advances in both the level of sophistication and computational efficiency of available computer hardware and the codes themselves now permit long-term simulations to be conducted in reasonable times. Thus, these codes provide a unique capability to evaluate the spectral content of the fatigue loads on a turbine. To demonstrate these capabilities, a Micon 65/13 turbine is analyzed using the YawDyn and the ADAMS dynamic analysis codes. The SNLWIND-3D simulator and measured boundary conditions are used to simulate the inflow environment that can be expected during a single, 24-hour period by a turbine residing in Row 41 of a wind farm located in San Gorgonio Pass, California. Also, long-term simulations (up to 8 hours of simulated time) with constant average inflow velocities are used to better define the characteristics of the fatigue load on the turbine. Damage calculations, using the LIFE2 fatigue analysis code and the MSU/DOE fatigue data base for composite materials, are then used to determine minimum simulation times for consistent estimates of service lifetimes.

  1. NWTC Researchers Field-Test Advanced Control Turbine Systems to Increase Performance, Decrease Structural Loading of Wind Turbines and Plants

    SciTech Connect

    2015-08-01

    Researchers at the National Renewable Energy Laboratory's (NREL's) National Wind Technology Center (NWTC) are studying component controls, including new advanced actuators and sensors, for both conventional turbines as well as wind plants. This research will help develop innovative control strategies that reduce aerodynamic structural loads and improve performance. Structural loads can cause damage that increase maintenance costs and shorten the life of a turbine or wind plant.

  2. A 100-kW wind turbine blade dynamics analysis, weight-balance, and structural test results

    NASA Technical Reports Server (NTRS)

    Anderson, W. D.

    1975-01-01

    The results of dynamic analyses, weight and balance tests, static stiffness tests, and structural vibration tests on the 60-foot-long metal blades for the ERDA-NASA 100-kW wind turbine are presented. The metal blades are shown to be free from structural or dynamic resonance at the wind turbine design speed. Aeroelastic instabilities are unlikely to occur within the normal operating range of the wind turbine.

  3. Vertical and Horizontal Wind Structure Prior to and During the 1997/1998 ENSO Event

    NASA Technical Reports Server (NTRS)

    Adamec, David

    1998-01-01

    Analyses of ECMWF and satellite wind products are used to investigate low frequency fluctuations in the wind fields immediately preceding and during the 1997/1998 ENSO event. An extended EOF analysis of the horizontal and vertical wind structure that allows for the study of propagating features indicates that the dominant mode of variability established in the lower levels of the atmosphere is a convergence in the central tropical Pacific. At mid-levels, the westerlies increase with time over most of the equatorial Pacific, and there are closed cyclonic features on either side of the equator. At upper levels, the flow tends to become divergent across the equatorial Pacific, and there is a strong flow from the northwest Pacific across Indonesia that then turns to the west along the equator in the Indian Ocean. The addition of satellite data for improved surface wind estimates reveal that the Indian Ocean winds were anomalously strong during the winter preceding the initiation of the ENSO event. An analysis of the momentum convergence flux at the surface indicates a very strong anomaly 9 months prior to the ENSO event that begins in the western Indian Ocean and propagates to the east, arriving over the Pacific warm pool area coincident with the beginning of the El Nino. Changes in the near surface thermal and water vapor structure over the Indian Ocean during this period will also be discussed.

  4. Influence of coherent mesoscale structures on satellite-based Doppler lidar wind measurements

    NASA Technical Reports Server (NTRS)

    Emmitt, G. D.

    1985-01-01

    The influence of coherent mesoscale structures on satellite based Doppler lidar wind measurements was investigated. Range dependent weighting functions and the single shot SNR of scan angle are examined and a space shuttle lidar experiment which used a fixed beam and rotating shuttle is simulated.

  5. Simulation of wind effects on tall structures by finite element method

    NASA Astrophysics Data System (ADS)

    Ebrahimi, Masood

    2015-07-01

    In the present study finite element method is used to predict the wind forces on a tall structure. The governing equations of mass and momentum with boundary conditions are solved. The κ-ɛ turbulence model is utilized to calculate the turbulence viscosity. The results are independent from the generated mesh. The numerical results are validated with American Society of Civil Engineering standards.

  6. Simulation of wind effects on tall structures by finite element method

    NASA Astrophysics Data System (ADS)

    Ebrahimi, Masood

    2016-06-01

    In the present study finite element method is used to predict the wind forces on a tall structure. The governing equations of mass and momentum with boundary conditions are solved. The κ- ɛ turbulence model is utilized to calculate the turbulence viscosity. The results are independent from the generated mesh. The numerical results are validated with American Society of Civil Engineering standards.

  7. Three-dimensional structure of the wind-driven water surface flow

    NASA Astrophysics Data System (ADS)

    Caulliez, Guillemette

    2014-05-01

    The structure of the water boundary layer forced by wind underneath surface wind waves is investigated experimentally in the large Marseille-Luminy wind wave tank. Measurements of the vertical velocity profiles inside the subsurface shear layer were performed by a three-component Nortek acoustic Doppler velocimeter. An overview of the water surface flow patterns which develop at larger scales was provided by simultaneous flow visualizations. To that end, tiny hydrogen bubbles were generated by electrolysis along a 60 cm long thin wire set up crosswise to the wind direction at a short distance from the water surface. The bubble motions were recorded by a video camera looking vertically from below or above the water surface. Observations were made at low to moderate wind speeds for four fetches ranging from 2 to 26 m. This work reveals that under such steady wind conditions, the transition of the water surface boundary layer to turbulent flow is marked by the fast development of coherent longitudinal vortices downstream the surface wave generation area observed at short fetches. These structures are characterized by the occurrence of intense upwellings localized in narrow streaks in the crosswise direction. There, the upper wind-induced shear flow is confined in a very thin layer. In the wider areas between these streaks, the surface flow exhibits a much more turbulent behaviour over a deeper but slightly-sheared boundary layer. In accordance with this inhomogeneous flow pattern, the velocity field observed at a fixed location over one vertical profile is highly variable in time. These three-dimensional large-scale structures present strong similarities with the so-called Langmuir circulations. This work will focus on the description of the qualitative and quantitative properties of these longitudinal vortices, in particular the conditions of their occurence and the dependency of their characteristic scales on wind forcing and surface wave development. The main

  8. Compressible coherent structures at ion scales in the slow solar wind

    NASA Astrophysics Data System (ADS)

    Perrone, Denise; Alexandrova, Olga; Mangeney, Andre; Maksimovic, Milan; Lacombe, Catherine

    2016-04-01

    We present a study of magnetic field fluctuations close to the ion scales in a slow solar wind stream. The nature of these fluctuations is found to be characterized by coherent structures. Although previous studies have shown that coherent current sheets can be considered as the principal cause of intermittency at the solar wind ion scales, here we show for the first time that, in the case of the slow solar wind, a large variety of coherent structures participates to intermittency at proton scales, and current sheets are not the most common ones. Precisely, we find here compressible (δB∥ ≫ δB⊥), linearly polarized structures in form of magnetic holes, solitons and shock waves. Examples of Alfvénic structures (δB⊥ > δB∥) are identified as current sheets and vortex-like structures. Some of these vortices have δB⊥≫ δB∥, but the majority of them are characterized by δB⊥ ≳ δB∥. Thanks to multi-point measurements by Cluster spacecraft, we could determine the normal of the coherent structures and their propagation velocity and spatial scale along this normal. Independently of the nature of the structures, the normal is always perpendicular to the local magnetic field, meaning that k⊥ ≫ k∥. The spatial scales of the studied structures are found to be 2 to 5 times the proton gyroradius or proton inertial length. Most of them are simply convected by the wind, but 25% propagate in the plasma frame. Possible interpretations of the observed structures and the connection with the plasma heating are discussed.

  9. Structural characterization of wind-sheared turbulent flow using self-organized mapping

    NASA Astrophysics Data System (ADS)

    Scott, Nicholas V.; Handler, Robert A.

    2016-05-01

    A nonlinear cluster analysis algorithm is used to characterize the spatial structure of a wind-sheared turbulent flow obtained from the direct numerical simulation (DNS) of the three-dimensional temperature and momentum fields. The application of self-organizing mapping to DNS data for data reduction is utilized because of the dimensional similitude in structure between DNS data and remotely sensed hyperspectral and multispectral data where the technique has been used extensively. For the three Reynolds numbers of 150, 180, and 220 used in the DNS, self-organized mapping is successful in the extraction of boundary layer streaky structures from the turbulent temperature and momentum fields. In addition, it preserves the cross-wind scale structure of the streaks exhibited in both fields which loosely scale with the inverse of the Reynolds number. Self-organizing mapping of the along wind component of the helicity density shows a layer of the turbulence field which is spotty suggesting significant direct coupling between the large and small-scale turbulent structures. The spatial correlation of the temperature and momentum fields allows for the possibility of the remote extrapolation of the momentum structure from thermal structure.

  10. An extended structure-function model and its application to the analysis of solar wind intermittency

    NASA Technical Reports Server (NTRS)

    Tu, C.-Y.; Marsch, E.; Rosenbauer, H.

    1995-01-01

    An extended structure-function model is developed by including the new effect in the p-model of Meneveau and Sreenivasan (1987a), i.e., that the averaged energy cascade rate changes with scale, a situation which has been found to prevail in non-fully-developed turbulence in the inner solar wind. This model is useful for the small-scale fluctuations in the inner heliosphere, where the turbulence is not fully developed and cannot be explained quantitatively by any of the previous intermittency turbulence models. With two model parameters, the intrinsic index of the energy spectrum, alpha and the fragmentation fraction p, the model can fit, for the first time, all the observed scaling exponents of the structure functions, which are calculated for time lags ranging from 81 seconds to 0.7 hours from the Helios solar wind data. From the cases we studied we can establish for p neither a clear radial evolution trend, nor a solar-wind-speed, or stream-structure dependence, or a systematic anisotropy for both the flow velocity and magnetic field component fluctuations. Generally, p has values between 0. 7 and 0.8. However, in some cases in low-speed wind p has somewhat higher values for the magnetic components, especially for the radial component. In high-speed wind, the inferred intrinsic spectral indices (alpha) of the velocity and magnetic field components are about equal, while the experimental spectral indices derived from the observed power spectra differ. The magnetic index is somewhat larger than the index of the velocity spectrum. For magnetic fluctuations in both high- and low-speed winds, the intrinsic exponent alpha has values which are near 1.5, while the observed spectral exponent has much higher values.

  11. Teaching Technology-Structure Contingencies by "Harnessing the Wind"

    ERIC Educational Resources Information Center

    Miller, Lynn E.

    2007-01-01

    This article describes a role-playing simulation that demonstrates how organizational structure is influenced by organizational and departmental technologies. Students act as employees of firms that must manufacture either a range of innovative products or a large number of standardized products. The simulation can be used in organizational…

  12. Multi-spacecraft observations of heliographic latitude-longitude structure in the solar wind

    NASA Technical Reports Server (NTRS)

    Rhodes, E. J., Jr.; Smith, E. J.

    1981-01-01

    The heliographic latitude-longitude structure of high speed solar winds observed prior to the maximum of sunspot cycle 20 is investigated by multi-spacecraft comparisons. It is shown that differences in solar wind structures are due to two different kinds of spatial structures. One structure is found to be consistent with the simultaneous existence of a single, broad stream at latitudes above 7 deg N and a series of narrow streams at lower latitudes, while the other is consistent with the existence of a latitudinally sloping stream boundary near the solar equator. For latitude separations less than 3.5 deg, cross-correlations of Explorer-Mariner velocities show only previously reported systematic increases in velocity with latitude, and for latitude separations from 3.5 to 6.2 deg, differences in high speed streams shift in longitude and/or amplitude are also identified on a timescale of one solar rotation.

  13. Wind energy systems

    NASA Technical Reports Server (NTRS)

    Stewart, H. J.

    1978-01-01

    A discussion on wind energy systems involved with the DOE wind energy program is presented. Some of the problems associated with wind energy systems are discussed. The cost, efficiency, and structural design of wind energy systems are analyzed.

  14. Smart Sensor System for Structural Condition Monitoring of Wind Turbines: 30 May 2002--30 April 2006

    SciTech Connect

    Schulz, M. J.; Sundaresan, M. J.

    2006-08-01

    This report describes the efforts of the University of Cincinnati, North Carolina A&T State University, and NREL to develop a structural neural system for structural health monitoring of wind turbine blades.

  15. Investigation of the adhesive bonding technology for the insulator structure of EAST neutral beam injector

    NASA Astrophysics Data System (ADS)

    Wei, Jiang-Long; Li, Jun; Hu, Chun-Dong; Xie, Ya-Hong; Jing, Hao

    2014-07-01

    A key issue on the development of EAST ion source was the junction design of insulator structure, which consists of three insulators and four supporting flanges of electrode grid. Because the ion source is installed on the vertical plane, the insulator structure has to withstand large bending and shear stress due to the gravity of whole ion source. Through a mechanical analysis, it was calculated that the maximum bending normal stress was 0.34 MPa and shear stress was 0.23 MPa on the insulator structure. Due to the advantages of simplicity and high strength, the adhesive bonding technology was applied to the junction of insulator structure. A tensile testing campaign of different junction designs between insulator and supporting flange was performed, and a junction design of stainless steel and fiber enhanced epoxy resin with epoxy adhesive was determined. The insulator structure based on the determined design can satisfy both the requirements of high-voltage holding and mechanical strength.

  16. Investigation of the adhesive bonding technology for the insulator structure of EAST neutral beam injector

    SciTech Connect

    Wei, Jiang-Long Li, Jun; Hu, Chun-Dong; Xie, Ya-Hong; Jing, Hao

    2014-07-15

    A key issue on the development of EAST ion source was the junction design of insulator structure, which consists of three insulators and four supporting flanges of electrode grid. Because the ion source is installed on the vertical plane, the insulator structure has to withstand large bending and shear stress due to the gravity of whole ion source. Through a mechanical analysis, it was calculated that the maximum bending normal stress was 0.34 MPa and shear stress was 0.23 MPa on the insulator structure. Due to the advantages of simplicity and high strength, the adhesive bonding technology was applied to the junction of insulator structure. A tensile testing campaign of different junction designs between insulator and supporting flange was performed, and a junction design of stainless steel and fiber enhanced epoxy resin with epoxy adhesive was determined. The insulator structure based on the determined design can satisfy both the requirements of high-voltage holding and mechanical strength.

  17. A NASTRAN-based computer program for structural dynamic analysis of Horizontal Axis Wind Turbines

    NASA Technical Reports Server (NTRS)

    Lobitz, Don W.

    1995-01-01

    This paper describes a computer program developed for structural dynamic analysis of horizontal axis wind turbines (HAWT's). It is based on the finite element method through its reliance on NASTRAN for the development of mass, stiffness, and damping matrices of the tower end rotor, which are treated in NASTRAN as separate structures. The tower is modeled in a stationary frame and the rotor in one rotating at a constant angular velocity. The two structures are subsequently joined together (external to NASTRAN) using a time-dependent transformation consistent with the hub configuration. Aerodynamic loads are computed with an established flow model based on strip theory. Aeroelastic effects are included by incorporating the local velocity and twisting deformation of the blade in the load computation. The turbulent nature of the wind, both in space and time, is modeled by adding in stochastic wind increments. The resulting equations of motion are solved in the time domain using the implicit Newmark-Beta integrator. Preliminary comparisons with data from the Boeing/NASA MOD2 HAWT indicate that the code is capable of accurately and efficiently predicting the response of HAWT's driven by turbulent winds.

  18. A NASTRAN-based computer program for structural dynamic analysis of Horizontal Axis Wind Turbines

    NASA Astrophysics Data System (ADS)

    Lobitz, Don W.

    1995-05-01

    This paper describes a computer program developed for structural dynamic analysis of horizontal axis wind turbines (HAWT's). It is based on the finite element method through its reliance on NASTRAN for the development of mass, stiffness, and damping matrices of the tower end rotor, which are treated in NASTRAN as separate structures. The tower is modeled in a stationary frame and the rotor in one rotating at a constant angular velocity. The two structures are subsequently joined together (external to NASTRAN) using a time-dependent transformation consistent with the hub configuration. Aerodynamic loads are computed with an established flow model based on strip theory. Aeroelastic effects are included by incorporating the local velocity and twisting deformation of the blade in the load computation. The turbulent nature of the wind, both in space and time, is modeled by adding in stochastic wind increments. The resulting equations of motion are solved in the time domain using the implicit Newmark-Beta integrator. Preliminary comparisons with data from the Boeing/NASA MOD2 HAWT indicate that the code is capable of accurately and efficiently predicting the response of HAWT's driven by turbulent winds.

  19. Fluid-structure coupling for wind turbine blade analysis using OpenFOAM

    NASA Astrophysics Data System (ADS)

    Dose, Bastian; Herraez, Ivan; Peinke, Joachim

    2015-11-01

    Modern wind turbine rotor blades are designed increasingly large and flexible. This structural flexibility represents a problem for the field of Computational Fluid Dynamics (CFD), which is used for accurate load calculations and detailed investigations of rotor aerodynamics. As the blade geometries within CFD simulations are considered stiff, the effect of blade deformation caused by aerodynamic loads cannot be captured by the common CFD approach. Coupling the flow solver with a structural solver can overcome this restriction and enables the investigation of flexible wind turbine blades. For this purpose, a new Finite Element (FE) solver was implemented into the open source CFD code OpenFOAM. Using a beam element formulation based on the Geometrically Exact Beam Theory (GEBT), the structural model can capture geometric non-linearities such as large deformations. Coupled with CFD solvers of the OpenFOAM package, the new framework represents a powerful tool for aerodynamic investigations. In this work, we investigated the aerodynamic performance of a state of the art wind turbine. For different wind speeds, aerodynamic key parameters are evaluated and compared for both, rigid and flexible blade geometries. The present work is funded within the framework of the joint project Smart Blades (0325601D) by the German Federal Ministry for Economic Affairs and Energy (BMWi) under decision of the German Federal Parliament.

  20. Diurnal Evolution of Three-Dimensional Wind and Temperature Structure in California's Central Valley

    SciTech Connect

    Zhong, Shiyuan; Whiteman, Charles D.; Bian, Xindi

    2004-11-01

    The diurnal evolution of the three-dimensional summer season mean wind and temperature structure in California’s Sacramento and San Joaquin Valleys (collectively called the Central Valley) are investigated using data from 22 radar wind profiler/Radio Acoustic Sounding Systems (RASS) operated as part of the Central California Ozone Study in 2000. The profiler network revealed, for the first time, that the persistent summer season flow pattern documented by surface observations extends 800-1000 m above the surface. At most locations, up-valley winds persist both day and night except at the upper ends of the valleys and close to the valley sidewalls where diurnal wind reversals occur. Wind speeds exhibit pronounced diurnal oscillations, with amplitudes decreasing with height. A low-level wind maximum occurs in the lowest 300 m, with a sharp decrease in speed above the maximum. Especially well-defined nocturnal low-level jets occur at sites in the southern San Joaquin Valley, where maximum speeds of 10 m s-1 or more occur 1-2 h before midnight at heights near 300 m. The afternoon mixed layer, generally deeper than 1000 m, increases in depth with up-valley distance in both valleys. At night, temperature inversions develop in the lowest several hundred meters with near-isothermal layers above. Mean temperatures in the lowest 500 m of the valleys are always warmer than at the same altitude over the coast, and temperature increases from the lower to upper valleys. The diurnal oscillation of the coast-valley and along-valley temperature and pressure difference reach a maximum in late afternoon and a minimum in early morning. These oscillations are in phase with the diurnal variation of westerly onshore flows. The along-valley wind maxima, however, occur 1-2 h before midnight while the pressure gradient maxima are usually found just before sunset.

  1. Potential of Energetic Neutral Helium Atoms to Resolve Structure of the Local Interstellar Medium within 0.1 Parsec

    NASA Astrophysics Data System (ADS)

    Swaczyna, P.; Grzedzielski, S.; Bzowski, M.

    2014-12-01

    Expected fluxes of energetic neutral helium atoms (He ENA) emitted from the heliosheath and created by the Ribbon secondary ENA mechanism are relatively small for the directions of the nose and flanks of the heliosphere. The mean free path against ionization in the Local Interstellar Cloud (LIC) for the He ENA reaches ~8,000 AU for atoms of energy ~5 keV, i.e., about 10 times higher than the mean free path against ionization for hydrogen atoms for the same energy. Thus observation of potential sources in the Local Interstellar Medium by an ENA detector could be possible for distances over a dozen thousand AU. This includes a potential to observe processes at the LIC boundary, to which the closest distance is likely smaller than 10,000 AU. Measurements of He ENA could potentially be used to bridge the gap between direct in situ sampling of our Galactic environment, available from Ulysses and IBEX, and the parsec-scale telescopic observations of interstellar absorption lines. Estimates of the expected heliospheric emission of He ENA are taken from a simple model of the heliosphere, for which we have obtained results consistent with HSTOF observation of He ENA. We use analytical model of the secondary ENA emission with a simple heliolatitude dependence in the supersonic solar wind. For the extraheliospheric sources, we examine simple He ENA production models on distant (<~0.1 pc) boundary layer. One such model, proposed earlier as an extraheliospheric source for the IBEX Ribbon at the hypothetic interface between the LIC and the Local Bubble, is now extended to provide estimates of the fluxes at a wider energy range, from a few to a few tens of keV, taking various distances to the interface into account. Including an appropriate mass spectrometer in the IMAP energetic neutral atom detector will give opportunity to distinguish helium atoms from the general ENA flux. This added capability would provide IMAP with a potential to discover possible enhancements in the He

  2. ALMA Data Suggest the Presence of Spiral Structure in the Inner Wind of CW Leo

    NASA Astrophysics Data System (ADS)

    Ward, H.; Leen, D.

    2015-12-01

    Evolved low-mass stars lose a significant fraction of their mass through stellar winds. While the overall morphology of the stellar wind structure during the asymptotic giant branch (AGB) phase is thought to be roughly spherically symmetric, the morphology changes dramatically during the post-AGB and planetary nebula phase, during which bipolar and multi-polar structures are often observed. We have observed the close-by carbon-rich AGB star CW Leo using ALMA (Cycle 0) in band 9 around 650 GHz. The channel maps and position-velocity diagram of the 13CO J=6-5 line show a complex structure. Using detailed 3D radiative transfer models, we show that the curved structure in the position velocity map of the 13CO J=6-5 line can be explained by a spiral structure in the inner wind of CW Leo, probably induced by a binary companion. From modelling the ALMA data, we deduce that the potential orbital axis for the binary system lies at a position angle of 10 to 20 degrees to the north-east and that the spiral structure is seen almost edge-on. We infer an orbital period of 55 yr and a binary separation of 25 au (or 8.2 stellar radii). We tentatively estimate that the companion is an unevolved low-mass main sequence star.

  3. Longitudinal structure in atomic oxygen concentrations observed with WINDII on UARS. [Wind Imaging Interferometer

    NASA Technical Reports Server (NTRS)

    Shepherd, G. G.; Thuillier, G.; Solheim, B. H.; Chandra, S.; Cogger, L. L.; Duboin, M. L.; Evans, W. F. J.; Gattinger, R. L.; Gault, W. A.; Herse, M.

    1993-01-01

    WINDII, the Wind Imaging Interferometer on the Upper Atmosphere Research Satellite, began atmospheric observations on September 28, 1991 and since then has been collecting data on winds, temperatures and emissions rates from atomic, molecular and ionized oxygen species, as well as hydroxyl. The validation of winds and temperatures is not yet complete, and scientific interpretation has barely begun, but the dominant characteristic of these data so far is the remarkable structure in the emission rate from the excited species produced by the recombination of atomic oxygen. The latitudinal and temporal variability has been noted before by many others. In this preliminary report on WINDII results we draw attention to the dramatic longitudinal variations of planetary wave character in atomic oxygen concentration, as reflected in the OI 557.7 nm emission, and to similar variations seen in the Meine1 hydroxyl band emission.

  4. Wind tunnel measurements in the wake of a simple structure in a simulated atmospheric flow

    NASA Technical Reports Server (NTRS)

    Hansen, A. C.; Peterka, J. A.; Cermak, J. E.

    1975-01-01

    Measurements of longitudinal mean velocity and turbulence intensity were made in the wake of a rectangular model building in a simulated atmospheric boundary-layer wind. The model building was a 1:50 scale model of a structure used in a wake measurement program at the George C. Marshall Space Flight Center 8-tower boundary-layer facility. The approach wind profile and measurement locations were chosen to match the field site conditions. The wakes of the building in winds from azimuths of 0 and 47 degrees referenced to the normal to the building long axis were examined. The effect of two lines of trees upwind of the building on the wake and the importance of the ratio of the building height to boundary-layer thickness on the extent of the wake were determined.

  5. Forced vibration analysis of rotating structures with application to vertical axis wind turbines

    NASA Astrophysics Data System (ADS)

    Lobitz, D. W.

    Predictive methods for the dynamic analysis of wind turbine systems are important for assessing overall structural integrity and fatigue life. For the former, the identification of resonance points (spectral analysis) is of primary concern. For the latter forced vibration analysis is necessary. These analyses are complicated by the fact that, for a spinning turbine, the stress-producing deformations take place in both fixed and rotating reference systems simultaneously. As an example, the tower of a horizontal axis wind turbine (HAWT) must be analyzed in a fixed frame, and the rotor in a rotating one. Forced vibration analysis is further complicated in that accurate models need to be developed for aeroload prediction. Methods which are available for forced vibration analysis of both horizontal and vertical axis machines are identified and the method which was developed for vertical axis wind turbines is emphasized, with some comparisons of the predictions to experimental data.

  6. On the Possibility of Study of the External Solar Wind Thin Structure in Decameter Radio Waves

    NASA Astrophysics Data System (ADS)

    Olyak, M. R.

    2006-08-01

    The purpose of this work is to develop the research technique of the thin structure of outer solar wind in decameter waves. The extended medium model and Feynman path-integral method were applied for calculations of the cross - spectra of weak interplanetary scintillations. The temporary spectra W(f) and phase speed dispersion dependencies V(f) for the spherically symmetric (curves 1) and two-high-speed (curves 2) models of solar wind were calculated. The meanings of solar wind parameters were chosen so that the differences of temporary spectra for two models were minimal and laid within the limits of probable measurements errors ([S:f:S][Author ID2: at Fri Jul 14 10:28:00 2006 ] F[Author ID2: at Fri Jul 14 10:28:00 2006 ]ig. 1). It is shown that the supervision of scintillations on two spatially carried antennas and study of dispersion dependence of phase speed will allow to notice the presence of the accelerated flows on a beam of sight when the measurements on one antenna do not give the unequivocal answer to the question whether the flows of solar wind with various speeds are present in external areas of interplanetary medium. It is shown that by using of simultaneous measurements of temporary spectra and dispersion dependences of phase speed the detection of fast and slow solar wind flows and the definition of their parameters are possible in decameter radio waves.

  7. Structural Load Analysis of a Wind Turbine under Pitch Actuator and Controller Faults

    NASA Astrophysics Data System (ADS)

    Etemaddar, Mahmoud; Gao, Zhen; Moan, Torgeir

    2014-12-01

    In this paper, we investigate the characteristics of a wind turbine under blade pitch angle and shaft speed sensor faults as well as pitch actuator faults. A land-based NREL 5MW variable speed pitch reg- ulated wind turbine is considered as a reference. The conventional collective blade pitch angle controller strategy with independent pitch actuators control is used for load reduction. The wind turbine class is IEC-BII. The main purpose is to investigate the severity of end effects on structural loads and responses and consequently identify the high-risk components according to the type and amplitude of fault using a servo-aero-elastic simulation code, HAWC2. Both transient and steady state effects of faults are studied. Such information is useful for wind turbine fault detection and identification as well as system reliability analysis. Results show the effects of faults on wind turbine power output and responses. Pitch sensor faults mainly affects the vibration of shaft main bearing, while generator power and aerodynamic thrust are not changed significantly, due to independent pitch actuator control of three blades. Shaft speed sensor faults can seriously affect the generator power and aerodynamic thrust. Pitch actuator faults can result in fully pitching of the blade, and consequently rotor stops due to negative aerodynamic torque.

  8. HARLIE Aerosol and Cloud Structure and Wind Observations during HARGLO and IHOP

    NASA Technical Reports Server (NTRS)

    Schwemmer, Geary K.; Miller, David O.; Wilkersorf, Thomas D.

    2003-01-01

    The Holographic Airborne Rotating Lidar Instrument Experiment (HARLIE) is a conical-scanning, 1-micron wavelength lidar that has been adapted for ground-based applications and used to infer horizontal wind information by tracking the motions of aerosol and cloud scattering structures. In addition, HARLIE's rapid continuous scanning enables boundary layer statistics and a new cloud lidar data product that gives cloud coverage as a function of altitude with high temporal resolution. HARLIE has been used in several field campaigns while developing the techniques for wind, boundary layer (BL), and cloud data products. These campaigns involved a variety of wind measuring instruments including rawindsondes, cloud-tracked winds from video imagery, Doppler lidars and Doppler radars. HARGLO-2 was one of these campaigns and was dedicated to wind profile intercomparisons over a 1-week period in November of 2001. The most recent of these campaigns was the International H20 Project (IHOP) located in the Southern Great Plains of the US during May and June of 2002.

  9. Wind structure and variability in the middle atmosphere during the November 1980 energy budget campaign

    NASA Technical Reports Server (NTRS)

    Schmidlin, F. J.; Carlson, M.; Rees, D.; Offermann, D.; Philbrick, C. R.; Widdel, H. U.

    1985-01-01

    Between November 6 and December 1, 1980 series of rocket observations were obtained from two sites in northern Scandinavia (68 deg N) as part of the Energy Budget Campaign, revealing the presence of significant vertical and temporal changes in the wind structure. These changes coincided with different geomagnetic conditions, i.e. quiet and enhanced. Large amounts of rocket data were gathered from high latitudes over such a short interval of time. Prior to November 16 the meridional wind component above 60 km was found to be positive (southerly), while the magnitude of the zonal wind component incresed with altitude. After November 16 the meridional component became negative (northerly) and the magnitude of the zonal wind component was noted to decrease with altitude. Time-sections of the perturbations of the zonal wind show the presence of vertically propagating waves, which suggest gravity wave activity. These waves increase in length from 1 km near 30 km to over 12 km near 80 km. The observational techniques employed Andoya (69 deg N), Norway, and Esrange (67.9 deg N), Sweden, consisted of chaff foil, instrumented rigid spheres, chemical trails, inflatable spheres and parachutes.

  10. The average solar wind in the inner heliosphere: Structures and slow variations

    NASA Technical Reports Server (NTRS)

    Schwenn, R.

    1983-01-01

    Measurements from the HELIOS solar probes indicated that apart from solar activity related disturbances there exist two states of the solar wind which might result from basic differences in the acceleration process: the fast solar wind (v 600 kms(-)1) emanating from magnetically open regions in the solar corona and the "slow" solar wind (v 400 kms(-)1) correlated with the more active regions and its mainly closed magnetic structures. In a comprehensive study using all HELIOS data taken between 1974 and 1982 the average behavior of the basic plasma parameters were analyzed as functions of the solar wind speed. The long term variations of the solar wind parameters along the solar cycle were also determined and numerical estimates given. These modulations appear to be distinct though only minor. In agreement with earlier studies it was concluded that the major modulations are in the number and size of high speed streams and in the number of interplanetary shock waves caused by coronal transients. The latter ones usually cause huge deviations from the averages of all parameters.

  11. The atmosphere structure of coronal hole and solar wind parameters connection

    NASA Astrophysics Data System (ADS)

    Prosovetsky, Dmitry; Myagkova, Irina

    The problem of high-speed solar wind acceleration and the dependence of its parameters on atmosphere structure of coronal holes at different altitudes is one of the key problems in modern solar physics. UV and microwave observations may be useful for investigations in this direction. We have analyzed the results of measurements on board spacecrafts SOHO and ACE, and also the observation data in a microwave range obtained by radio heliographs of Nobeyama, SSR and Nancy, magnetic field measurements in an observatory the Kit Peak. The dependence of solar wind speed from magnetic flux at low levels of solar atmosphere was confirmed. However such dependence at coronal level was not founded. We notice this fact doesn't allow performing forecasting solar wind parameters from super-radial divergence of magnetic field lines. The strong dependence of solar wind speed from the flux of microwave emission has been founded for 17 GHz, 5.7 GHz and 327 MHz which correspond to altitudes from the top chro-mosphere to coronal heights. However such dependence is absent for frequency 150.9 MHz at high coronal levels. We assume this fact connected with the presence of two solar wind acceleration mechanisms from coronal holes of the middle and top corona. The observations of scintillation in the radio emissions of a solar corona for a high-speed and slow solar wind confirm this assumption. Geomagnetic disturbances depending on coronal hole structure at different altitudes of solar atmosphere were studied. The obtained results specify that high-latitude magnetic disturbances depend on relation of magnetic field vector component in coronal holes. During investigated time period the most powerful high latitude magnetic disturbances (Kp and AE) were observed when the southern magnetic field component dominates inside coronal holes at cromospheric altitudes.

  12. Strong wind structure near a sea-land roughness discontinuity

    NASA Astrophysics Data System (ADS)

    Sacré, C.

    1981-08-01

    During the winters of 1977 and 1978, the Centre Scientifique et Technique du Bâtiment (CSTB) carried out a study on the Atlantic littoral in order to determine the modifications to which an air flow is subjected in the surface boundary layer, as it crosses a sea-land discontinuity. The study shows that, in the zone directly leeward of the shore, the structure of the flow is strongly influenced by the acceleration effect of the dune and by the magnitude of the land roughness. In particular, there is a significant disturbance of the ‘logarithmic’ equilibrium of the air flow.

  13. General asymmetric neutral networks and structure design by genetic algorithms: A learning rule for temporal patterns

    SciTech Connect

    Bornholdt, S.; Graudenz, D.

    1993-07-01

    A learning algorithm based on genetic algorithms for asymmetric neural networks with an arbitrary structure is presented. It is suited for the learning of temporal patterns and leads to stable neural networks with feedback.

  14. Structure and oxidation state of hematite surfaces reacted with aqueous Fe(II) at acidic and neutral pH

    NASA Astrophysics Data System (ADS)

    Catalano, Jeffrey G.; Fenter, Paul; Park, Changyong; Zhang, Zhan; Rosso, Kevin M.

    2010-03-01

    Structural changes and surface oxidation state were examined following the reaction of hematite (0 0 1), (0 1 2), and (1 1 0) with aqueous Fe(II). X-ray reflectivity measurements indicated that Fe(II) induces changes in the structure of all three surfaces under both acidic (pH 3) and neutral (pH 7) conditions. The structural changes were generally independent of pH although the extent of surface transformation varied slightly between acidic and neutral conditions; no systematic trends with pH were observed. Induced changes on the (1 1 0) and (0 1 2) surfaces include the addition or removal of partial surface layers consistent with either growth or dissolution. In contrast, a <1 nm thick, discontinuous film formed on the (0 0 1) surface that appears to be epitaxial yet is not a perfect extension of the underlying hematite lattice, being either structurally defective, compositionally distinct, or nanoscale in size and highly relaxed. Resonant anomalous X-ray reflectivity measurements determined that the surface concentration of Fe(II) present after reaction at pH 7 was below the detection limit of approximately 0.5-1 μmol/m 2 on all surfaces. These observations are consistent with Fe(II) oxidative adsorption, whereby adsorbed Fe(II) is oxidized by structural Fe(III) in the hematite lattice, with the extent of this reaction controlled by surface structure at the atomic scale. The observed surface transformations at pH 3 show that Fe(II) oxidatively adsorbs on hematite surfaces at pH values where little net adsorption occurs, based on historical macroscopic Fe(II) adsorption behavior on fine-grained hematite powders. This suggests that Fe(II) plays a catalytic role, in which an electron from an adsorbed Fe(II) migrates to and reduces a lattice Fe(III) cation elsewhere, which subsequently desorbs in a scenario with zero net reduction and zero net adsorption. Given the general pH-independence and substantial mass transfer involved, this electron and atom exchange

  15. Theory for Electronic Structure and Associated Hyperfine Interactions for Neutral Vacancy-Associated Hydrogen (Muonium) Atom Center in Silicon

    NASA Astrophysics Data System (ADS)

    Li, Hong; Sahoo, N.; Das, T. P.; Scheuermann, R.; Nagamine, K.

    2001-03-01

    The electronic structure and associated magnetic hyperfine interactions for the Neutral Vacancy-Associated Hydrogen (Muonium) Atom Center(B. Bech Nielsen et al., Phys. Rev. Lett. 79, 1507 (1997))^,(M.Schefzik et al, Solid State Commun. 107, 395 (1998)) in Silicon have been investigated using theHartree-Fock Cluster Procedure combined with many-body effects incorporated by perturbation methods. The influence of cluster size, size of electronic basis-set and lattice relaxation due to the presence of both the vacancy and muonium atom, have been studied. The results provide an explanation of the axial anisotropy of the hyperfine interaction tensors and the signs of the isotropic hyperfine constant and dipolar tensor components. The sizes of the calculated hyperfine tensor components are however found to be somewhat larger than experiment. Possible sources that could bridge the differences will be discussed.

  16. Structure-Based Design of a Protein Immunogen that Displays an HIV-1 gp41 Neutralizing Epitope

    SciTech Connect

    Stanfield, Robyn L.; Julien, Jean-Philippe; Pejchal, Robert; Gach, Johannes S.; Zwick, Michael B.; Wilson, Ian A.

    2012-06-27

    Antibody Z13e1 is a relatively broadly neutralizing anti-human immunodeficiency virus type 1 antibody that recognizes the membrane-proximal external region (MPER) of the human immunodeficiency virus type 1 envelope glycoprotein gp41. Based on the crystal structure of an MPER epitope peptide in complex with Z13e1 Fab, we identified an unrelated protein, interleukin (IL)-22, with a surface-exposed region that is structurally homologous in its backbone to the gp41 Z13e1 epitope. By grafting the gp41 Z13e1 epitope sequence onto the structurally homologous region in IL-22, we engineered a novel protein (Z13-IL22-2) that contains the MPER epitope sequence for use as a potential immunogen and as a reagent for the detection of Z13e1-like antibodies. The Z13-IL22-2 protein binds Fab Z13e1 with a K{sub d} of 73 nM. The crystal structure of Z13-IL22-2 in complex with Fab Z13e1 shows that the epitope region is faithfully replicated in the Fab-bound scaffold protein; however, isothermal calorimetry studies indicate that Fab binding to Z13-IL22-2 is not a lock-and-key event, leaving open the question of whether conformational changes upon binding occur in the Fab, in Z13-IL-22, or in both.

  17. Experimental verification of isotope shift and hyperfine structure of some even parity levels of neutral Eu

    NASA Astrophysics Data System (ADS)

    Furmann, B.; Stefanska, D.

    2014-09-01

    The results of measurements of the hyperfine structure of 31 classified and four unclassified spectral lines in the europium atom, obtained by using the laser induced fluorescence method, are presented. On the basis of experimental results, the values of the hyperfine structure constants and the isotope shifts for seven hitherto unmeasured levels belonging to even configurations (among them for three entirely new levels with unknown energies) were determined and the respective values known from literature for another 19 levels were verified. Since the motivation for undertaking investigations within this work was an inconsistency in the semi-empirical description of the hyperfine structure and the isotope shifts for some even levels in the europium atom, a detailed discussion of this problem is presented.

  18. Flow structures around a gable-roofed building model in tornado-like winds

    NASA Astrophysics Data System (ADS)

    Yang, Zifeng; Balaramudu, Vasanth; Haan, Fred; Sarkar, Partha; Hu, Hui

    2007-11-01

    Tornadoes are violently rotating columns of air which are considered as nature's most violent storms. In an average year, 800 ˜ 1000 tornados would occur in the U.S. alone, and cause about 80 deaths (on average), over 1500 injuries, and 850 million worth of property damage. By using the world-largest tornado simulator of Iowa State University, a comprehensive experimental investigation was conducted to characterize the flow structures around a low-rise, gable-roofed building model in tornado-like winds. While pressure taps and force transducers were used to map the pressure distributions around the building model and measure the aerodynamic forces acting on the building model induced by the tornado-like winds, a high-resolution Particle Image Velocimetry (PIV) system was used to conduct detailed flow velocity field measurements around the gable-roofed building model. The ultimate objective of the present study is to quantify the surface winds generated by tornadoes and flow-structure interactions between tornadoes and built environments to assess wind-induced damage with the purpose of mitigating damage and improving public safety.

  19. Dynamics and Internal Structure of the Cross-Shelf Circulation During Wind-Driven Coastal Upwelling

    NASA Astrophysics Data System (ADS)

    Choboter, P. F.

    2007-12-01

    A two-dimensional theory of wind-driven coastal upwelling is developed that is comprised of a surface Ekman layer, an interior frictionless layer, and a frictional bottom boundary layer. The theory is built upon the Lentz- Chapman upwelling theory, which has been used to demonstrate the importance of nonlinear cross-shelf momentum flux divergence during upwelling. The new model retains spatially-varying structure in the interior density and velocity fields. The dynamical model for the interior flow is based upon the nonlinear upwelling theory of Pedlosky, which maintains thermal wind balance between the cross-shelf density gradient and the vertical shear in the alongshelf velocity while retaining the cross-shelf advection of density and alongshelf momentum. The structure of the cross-shelf circulation is studied as a function of alongshelf wind stress and Burger number S = α N/f, where α is the topographic slope, N is the buoyancy frequency, and f is the Coriolis parameter. Predictions of the dynamical model are compared with two-dimensional numerical model simulations. During upwelling winds, the dynamical model predicts interior onshore flow high in the water column for large Burger number, and onshore flow in the bottom boundary layer for small Burger number, consistent with the numerical model and with observations.

  20. The structure and appearance of winds from supercritical accretion disks. I - Numerical models

    NASA Technical Reports Server (NTRS)

    Meier, D. L.

    1979-01-01

    Equations for the structure and appearance of supercritical accretion disks and the radiation-driven winds which emanate from them are derived and solved by a steady-state hydrodynamic computer code with a relaxation technique used in stellar structure problems. The present model takes into account the mass of the accreting star, the total accretion rate, a generalization of the disk alpha parameter which accounts for heating by processes in addition to viscosity, and the ratio of the total luminosity to the Eddington luminosity. Solutions indicate that for accretion onto a hard-surfaced star, steady, optically thick winds result for even slightly supercritical accretion, and the object will appear as a supergiant star with a high mass loss rate and a nonblackbody spectrum. Winds from black hole accretion disks are expected to depend on the form of the accretion interior to the critical radius, possibly consisting of no ejection at all, a wind similar to that of a hard-surfaced star, or a column of material ejected from a hole in the accretion disk.

  1. Solar Wind Speed Structure in the Inner Corona at 3-12 Ro

    NASA Technical Reports Server (NTRS)

    Woo, Richard

    1995-01-01

    Estimates of solar wind speed obtained by Armstrong et al. [1986] based on 1983 VLA multiple-station intensity scintillation measurements inside 12 R(sub o) have been correlated with the electron density structure observed in white-light coronagraph measurements. The observed large- scale and apparently systematic speed variations are found to depend primarily on changes in heliographic latitude and longitude, which leads to the first results on large-scale speed structure in the acceleration region of the solar wind. Over an equatorial hole, solar wind speed is relatively steady, with peak-to-peak variations of 50 km/s and an average of 230 km/s. In contrast, the near-Sun flow speed across the streamer belt shows regular large-scale variations in the range of 100-300 km/s. Based on four groups of data, the gradient is 36 km/s per degree in heliocentric coordinates (corresponding to a rise of 260 km/s over a spatial distance on the Sun of two arcmin) with a standard deviation of 2.4 km/s per degree. The lowest speeds most likely coincide with the stalks of coronal streamers observed in white-light measurements. The detection of significant wind shear over the streamer belt is consistent with in situ and scintillation measurements showing that the density spectrum has a power-law form characteristic of fully developed turbulence over a much broader range of scales than in neighboring regions.

  2. Compressive Coherent Structures at Ion Scales in the Slow Solar Wind

    NASA Astrophysics Data System (ADS)

    Perrone, D.; Alexandrova, O.; Mangeney, A.; Maksimovic, M.; Lacombe, C.; Rakoto, V.; Kasper, J. C.; Jovanovic, D.

    2016-08-01

    We present a study of magnetic field fluctuations in a slow solar wind stream, close to ion scales, where an increase of the level of magnetic compressibility is observed. Here, the nature of these compressive fluctuations is found to be characterized by coherent structures. Although previous studies have shown that current sheets can be considered the principal cause of intermittency at ion scales, here we show for the first time that, in the case of the slow solar wind, a large variety of coherent structures contributes to intermittency at proton scales, and current sheets are not the most common. Specifically, we find compressive (δ {b}\\parallel \\gg δ {b}\\perp ), linearly polarized structures in the form of magnetic holes, solitons, and shock waves. Examples of Alfvénic structures (δ {b}\\perp \\gt δ {b}\\parallel ) are identified as current sheets and vortex-like structures. Some of these vortices have δ {b}\\perp \\gg δ {b}\\parallel , as in the case of Alfvén vortices, but the majority of them are characterized by δ {b}\\perp ≳ δ {b}\\parallel . Thanks to multi-point measurements by the Cluster spacecraft, for about 100 structures we could determine the normal, the propagation velocity, and the spatial scale along this normal. Independently of the nature of the structures, the normal is always perpendicular to the local magnetic field, meaning that k ⊥ ≫ k ∥. The spatial scales of the studied structures are found to be between two and eight times the proton gyroradius. Most of them are simply convected by the wind, but 25% propagate in the plasma frame. Possible interpretations of the observed structures and the connection with plasma heating are discussed.

  3. On the Launching and Structure of Radiatively Driven Winds in Wolf-Rayet Stars

    NASA Astrophysics Data System (ADS)

    Ro, Stephen; Matzner, Christopher D.

    2016-04-01

    Hydrostatic models of Wolf-Rayet (WR) stars typically contain low-density outer envelopes that inflate the stellar radii by a factor of several and are capped by a denser shell of gas. Inflated envelopes and density inversions are hallmarks of envelopes that become super-Eddington as they cross the iron-group opacity peak, but these features disappear when mass loss is sufficiently rapid. We re-examine the structures of steady, spherically symmetric wind solutions that cross a sonic point at high optical depth, identifying the physical mechanism through which the outflow affects the stellar structure, and provide an improved analytical estimate for the critical mass-loss rate above which extended structures are erased. Weak-flow solutions below this limit resemble hydrostatic stars even in supersonic zones; however, we infer that these fail to successfully launch optically thick winds. WR envelopes will therefore likely correspond to the strong, compact solutions. We also find that wind solutions with negligible gas pressure are stably stratified at and below the sonic point. This implies that convection is not the source of variability in WR stars, as has been suggested; however, acoustic instabilities provide an alternative explanation. Our solutions are limited to high optical depths by our neglect of Doppler enhancements to the opacity, and do not account for acoustic instabilities at high Eddington factors; yet, they do provide useful insights into WR stellar structures.

  4. On the Launching and Structure of Radiatively Driven Winds in Wolf–Rayet Stars

    NASA Astrophysics Data System (ADS)

    Ro, Stephen; Matzner, Christopher D.

    2016-04-01

    Hydrostatic models of Wolf–Rayet (WR) stars typically contain low-density outer envelopes that inflate the stellar radii by a factor of several and are capped by a denser shell of gas. Inflated envelopes and density inversions are hallmarks of envelopes that become super-Eddington as they cross the iron-group opacity peak, but these features disappear when mass loss is sufficiently rapid. We re-examine the structures of steady, spherically symmetric wind solutions that cross a sonic point at high optical depth, identifying the physical mechanism through which the outflow affects the stellar structure, and provide an improved analytical estimate for the critical mass-loss rate above which extended structures are erased. Weak-flow solutions below this limit resemble hydrostatic stars even in supersonic zones; however, we infer that these fail to successfully launch optically thick winds. WR envelopes will therefore likely correspond to the strong, compact solutions. We also find that wind solutions with negligible gas pressure are stably stratified at and below the sonic point. This implies that convection is not the source of variability in WR stars, as has been suggested; however, acoustic instabilities provide an alternative explanation. Our solutions are limited to high optical depths by our neglect of Doppler enhancements to the opacity, and do not account for acoustic instabilities at high Eddington factors; yet, they do provide useful insights into WR stellar structures.

  5. Structural characterization of neutral oligosaccharides with blood-group A and H activity isolated from bovine submaxillary mucin.

    PubMed Central

    Savage, A V; D'Arcy, S M; Donoghue, C M

    1991-01-01

    In this study we investigated the structures of 11 neutral oligosaccharides released from bovine submaxillary mucin by alkaline borohydride treatment and isolated by h.p.l.c. One hexa-, one penta-, three tetra-, four tri- and two di-saccharides containing core types 1, 2, 3 or 4 were obtained. We report their structures, determined by a combination of one- and two-dimensional 1H n.m.r. spectroscopy at 270 MHz and methylation analysis involving g.l.c.-m.s., along with their approximate molar ratios. Only three of these oligosaccharides have previously been reported in this source. Of the new oligosaccharides, one contains the blood-group-A antigenic determinant, two contain the blood-group-H type 2 determinant, while another contains the blood-group-H type 3 determinant. The oligosaccharide GlcNAc beta (1----6)[GlcNAc beta (1----3)]GalNAcol, although previously found as a core structure, has been isolated here as a novel trisaccharide. PMID:1718265

  6. Microtraps for neutral atoms using superconducting structures in the critical state

    SciTech Connect

    Emmert, A.; Brune, M.; Raimond, J.-M.; Nogues, G.; Lupascu, A.; Haroche, S.

    2009-12-15

    Recently demonstrated superconducting atom chips provide a platform for trapping atoms and coupling them to solid-state quantum systems. Controlling these devices requires a full understanding of the supercurrent distribution in the trapping structures. For type-II superconductors, this distribution is hysteretic in the critical state due to the partial penetration of the magnetic field in the thin superconducting film through pinned vortices. We report here an experimental observation of this memory effect. Our results are in good agreement with the predictions of the Bean model of the critical state without adjustable parameters. The memory effect allows to write and store permanent currents in micron-sized superconducting structures and paves the way toward engineered trapping potentials.

  7. Measurements of internal magnetic structures from neutral beam emission spectra in KSTAR

    NASA Astrophysics Data System (ADS)

    Ko, J.; Chung, J.; Song, M.; You, K. I.

    2012-10-01

    The magnetic pitch angle and the magnitude from magnetically confined fusion devices are measured by fitting the beam emission spectra under the motional Stark effect (MSE). Initial values for the free parameters in the complicated raw spectra are obtained from and constrained by the MSE model in the Atomic Data and Analysis Structure (ADAS) which uses a collisional-radiative model with level populations nlm-resolved up to n = 4 and a simple born approximation for ion-impact cross sections. This technique is examined for the MSE spectra taken from the KSTAR plasma discharges and its validity and applicability are discussed to directly infer the internal magnetic field structure with a wide range of pitch angles. The sensitivity of EFIT reconstruction on these internal magnetic data is also discussed.

  8. Anisotropy of the energetic neutral atom flux in the heliosphere

    NASA Technical Reports Server (NTRS)

    Gruntman, Michael A.

    1992-01-01

    Characteristics of the energetic neutral atoms born at the heliospheric interface are considered for plasma flow structure resulting from a two-shock model of the interaction between the solar wind and the interstellar medium. The energy distributions of heliospheric energetic neutral atoms (HELENAs) are calculated and it is shown that the HELENA flux is highly anisotropic at the earth's orbit. The characteristics of the HELENA flux are highly sensitive to the size of the heliosphere. This supports the conclusion that measurements of HELENAs from the earth's orbit would provide an efficient tool to remotely study the heliosphere.

  9. Trends in Energies and Geometric Structures of Neutral and Charged Aluminum Clusters.

    PubMed

    Fournier, René

    2007-05-01

    The minimum energy geometric structures of Aln, A[Formula: see text] , and A[Formula: see text] (4 ≤ n ≤ 15) are predicted from the results of "Tabu Search" (TS) global optimizations performed directly on the BPW91/LANL2DZ potential energy surface. In 24 of the 36 cases investigated, the TS delivered a lower energy structure than previously reported, in one case (A[Formula: see text] ) it failed to find the global minimum, and in the remaining 11 cases TS confirmed previous structures. All clusters (with 4 ≤ n ≤ 15) have the lowest spin state as their ground state except Al4 (triplet), A[Formula: see text] (quartet), A[Formula: see text] (triplet), and maybe A[Formula: see text] (singlet and triplet are degenerate). The 20-electron A[Formula: see text] and 40-electron A[Formula: see text] clusters are relatively stable compared to other clusters, on several criteria; to a lesser degree, Al7, Al12, and A[Formula: see text] are also stable. PMID:26627412

  10. Structural characterization of poorly-crystalline scorodite, iron(III)-arsenate co-precipitates and uranium mill neutralized raffinate solids using X-ray absorption fine structure spectroscopy

    SciTech Connect

    Chen, N; Jiang, D T; Cutler, J; Kotzer, T; Jia, Y F; Demopoulos, G P; Rowson, J W

    2009-12-01

    X-ray absorption fine structure (XAFS) is used to characterize the mineralogy of the iron(III)-arsenate(V) precipitates produced during the raffinate (aqueous effluent) neutralization process at the McClean Lake uranium mill in northern Saskatchewan, Canada. To facilitate the structural characterization of the precipitated solids derived from the neutralized raffinate, a set of reference compounds were synthesized and analyzed. The reference compounds include crystalline scorodite, poorly-crystalline scorodite, iron(III)-arsenate co-precipitates obtained under different pH conditions, and arsenate-adsorbed on goethite. The poorly-crystalline scorodite (prepared at pH 4 with Fe/As = 1) has similar As local structure as that of crystalline scorodite. Both As and Fe K-edge XAFS of poorly-crystalline scorodite yield consistent results on As-Fe (or Fe-As) shell. From As K-edge analysis the As-Fe shell has an inter-atomic distance of 3.33 ± 0.02 Å and coordination number of 3.2; while from Fe K-edge analysis the Fe-As distance and coordination number are 3.31 ± 0.02 Å and 3.8, respectively. These are in contrast with the typical arsenate adsorption on bidentate binuclear sites on goethite surfaces, where the As-Fe distance is 3.26 ± 0.03 Å and coordination number is close to 2. A similar local structure identified in the poorly-crystalline scorodite is also found in co-precipitation solids (Fe(III)/As(V) = 3) when precipitated at the same pH (pH = 4): As-Fe distance 3.30 ± 0.03 Å and coordination number 3.9; while at pH = 8 the co-precipitate has As-Fe distance of 3.27 ± 0.03 Å and coordination number about 2, resembling more closely the adsorption case. The As local structure in the two neutralized raffinate solid series (precipitated at pH values up to 7) closely resembles that in the poorly-crystalline scorodite. All of the raffinate solids have the same As-Fe inter-atomic distance as that in the poorly-crystalline scorodite, and a systematic decrease in the

  11. Structural design of the Sandia 34-M Vertical Axis Wind Turbine

    SciTech Connect

    Berg, D.E.

    1985-01-01

    Sandia National Laboratories, as the lead DOE laboratory for Vertical Axis Wind Turbine (VAWT) development, is currently designing a 34-meter diameter Darrieus-type VAWT. This turbine will be a research test bed which provides a focus for advancing technology and validating design and fabrication techniques in a size range suitable for utility use. Structural data from this machine will allow structural modeling to be refined and verified for a turbine on which the gravity effects and stochastic wind loading are significant. Performance data from it will allow aerodynamic modeling to be refined and verified. The design effort incorporates Sandia's state-of-the-art analysis tools in the design of a complete machine. This paper describes the analytic tools we are using, summarizes the conceptual design procedure and presents portions of our detailed design as it exists in September 1984.

  12. Structural Load Alleviation Applied to Next Generation Aircraft and Wind Turbines

    NASA Technical Reports Server (NTRS)

    Frost, Susan

    2011-01-01

    Reducing the environmental impact of aviation is a goal of the Subsonic Fixed Wing Project under the Fundamental Aeronautics Program of NASAs Aeronautics Research Mission Directorate. Environmental impact of aviation is being addressed by novel aircraft configurations and materials that reduce aircraft weight and increase aerodynamic efficiency. NASA is developing tools to address the challenges of increased airframe flexibility created by wings constructed with reduced structural material and novel light-weight materials. This talk will present a framework and demonstration of a flight control system using optimal control allocation with structural load feedback and constraints to achieve safe aircraft operation. As wind turbines age, they become susceptible to many forms of blade degradation. Results will be presented on work in progress that uses adaptive contingency control for load mitigation in a wind turbine simulation with blade damage progression modeled.

  13. Structure of relativistic shocks in pulsar winds: A model of the wisps in the Crab Nebula

    NASA Technical Reports Server (NTRS)

    Gallant, Yves A.; Arons, Jonathan

    1994-01-01

    We propose a model of a optical 'wisps' of the Crab Nebula, features observed in the nebular synchrotron surface brightness near the central pulsar, as manifestations of the internal structure of the shock terminating the pulsar wind. We assume that this wind is composed of ions and a much denser plasma of electrons and positrons, frozen together to a toroidal magnetic field and flowing relativistically. We construct a form of solitary wave model of the shock structure in which we self-consistently solve for the ion orbits and the dynamics of the relativistically hot, magnetized e(+/-) background flow. We ignore dispersion in the ion energies, and we treat the pairs as an adiabatic fluid. The synchrotron emission enhancements, observed as the wisps, are then explained as the regions where reflection of the ions in the self-consistent magnetic field causes compressions of the e(+/-).

  14. Understanding the Global Structure and Evolution of Coronal Mass Ejections in the Solar Wind

    NASA Technical Reports Server (NTRS)

    Riley, Pete

    2004-01-01

    This report summarizes the technical progress made during the first six months of the second year of the NASA Living with a Star program contract Understanding the global structure and evolution of coronal mass ejections in the solar wind, between NASA and Science Applications International Corporation, and covers the period November 18, 2003 - May 17,2004. Under this contract SAIC has conducted numerical and data analysis related to fundamental issues concerning the origin, intrinsic properties, global structure, and evolution of coronal mass ejections in the solar wind. During this working period we have focused on a quantitative assessment of 5 flux rope fitting techniques. In the following sections we summarize the main aspects of this work and our proposed investigation plan for the next reporting period. Thus far, our investigation has resulted in 6 refereed scientific publications and we have presented the results at a number of scientific meetings and workshops.

  15. Solar wind suprathermal electron Stahl widths across high-speed stream structures

    SciTech Connect

    Skoug, Ruth M; Steinberg, John T; Goodrich, Katherine A; Anderson, Brett R

    2011-01-03

    Suprathermal electrons (100-1500 eV) observed in the solar wind typically show a strahl distribution, that is, a beam directed away from the Sun along the magnetic field direction. The strahl width observed at 1 AU is highly variable, ranging from 10-70 degrees. The obsenred finite width of the strahl results from the competition between beam focusing as the interplanetary magnetic field strength drops with distance from the Sun, and pitch-angle scattering as the beam interacts with the solar wind plasma in transit from the sun. Here we examine strahl width, observed with ACE SWEPAM across high-speed stream structures to investigate variations in electron scattering as a function of local plasma characteristics. We find that narrow strahls (less than 20 degrees wide), indicating reduced scattering, are observed within high-speed streams. Narrow strahls are also observed in both very low temperature solar wind, in association with ICMEs. Case studies of high-speed streams typically show the strahl narrowing at the leading edge of the stream. In some cases, the strahl narrows at the reverse shock or pressure wave, in other cases at the stream interface. The narrowing can either occur discontinuously or gradually over a period of hours. Within the high-speed wind, the strahl remains narrow for a period of hours to days, and then gradually broadens. The strahl width is roughly constant at all energies across these structures. For some fraction of high-speed streams, counterstreaming is associated with passage of the corotating interaction region. In these cases, we find the widths of the two counterstreaming beams frequently differ by more than 40 degrees. This dramatic difference in strahl width contrasts with observations in the solar wind as a whole, in which counterstreaming strahls typically differ in width by less than 20 degrees.

  16. Fluid-structure interaction modeling of wind turbines: simulating the full machine

    NASA Astrophysics Data System (ADS)

    Hsu, Ming-Chen; Bazilevs, Yuri

    2012-12-01

    In this paper we present our aerodynamics and fluid-structure interaction (FSI) computational techniques that enable dynamic, fully coupled, 3D FSI simulation of wind turbines at full scale, and in the presence of the nacelle and tower (i.e., simulation of the "full machine"). For the interaction of wind and flexible blades we employ a nonmatching interface discretization approach, where the aerodynamics is computed using a low-order finite-element-based ALE-VMS technique, while the rotor blades are modeled as thin composite shells discretized using NURBS-based isogeometric analysis (IGA). We find that coupling FEM and IGA in this manner gives a good combination of efficiency, accuracy, and flexibility of the computational procedures for wind turbine FSI. The interaction between the rotor and tower is handled using a non-overlapping sliding-interface approach, where both moving- and stationary-domain formulations of aerodynamics are employed. At the fluid-structure and sliding interfaces, the kinematic and traction continuity is enforced weakly, which is a key ingredient of the proposed numerical methodology. We present several simulations of a three-blade 5~MW wind turbine, with and without the tower. We find that, in the case of no tower, the presence of the sliding interface has no effect on the prediction of aerodynamic loads on the rotor. From this we conclude that weak enforcement of the kinematics gives just as accurate results as the strong enforcement, and thus enables the simulation of rotor-tower interaction (as well as other applications involving mechanical components in relative motion). We also find that the blade passing the tower produces a 10-12 % drop (per blade) in the aerodynamic torque. We feel this finding may be important when it comes to the fatigue-life analysis and prediction for wind turbine blades.

  17. Breaking wave impact forces on truss support structures for offshore wind turbines

    NASA Astrophysics Data System (ADS)

    Cieślikiewicz, Witold; Gudmestad, Ove T.; Podrażka, Olga

    2014-05-01

    Due to depletion of the conventional energy sources, wind energy is becoming more popular these days. Wind energy is being produced mostly from onshore farms, but there is a clear tendency to transfer wind farms to the sea. The foundations of offshore wind turbines may be truss structures and might be located in shallow water, where are subjected to highly varying hydrodynamic loads, particularly from plunging breaking waves. There are models for impact forces prediction on monopiles. Typically the total wave force on slender pile from breaking waves is a superposition of slowly varying quasi-static force, calculated from the Morison equation and additional dynamical, short duration force due to the impact of the breaker front or breaker tongue. There is not much research done on the truss structures of wind turbines and there are still uncertainties on slamming wave forces, due to plunging breaking waves on those structures. Within the WaveSlam (Wave slamming forces on truss structures in shallow water) project the large scale tests were carried out in 2013 at the Large Wave Flume in Forschungszentrum Küste (FZK) in Hannover, Germany. The following institutions participated in this initiative: the University of Stavanger and the Norwegian University of Science and Technology (project management), University of Gdańsk, Poland, Hamburg University of Technology and the University of Rostock, Germany and Reinertsen AS, Norway. This work was supported by the EU 7th Framework Programme through the grant to the budget of the Integrating Activity HYDRALAB IV. The main aim of the experiment was to investigate the wave slamming forces on truss structures, development of new and improvement of existing methods to calculate forces from the plunging breakers. The majority of the measurements were carried out for regular waves with specified frequencies and wave heights as well as for the irregular waves based on JONSWAP spectrum. The truss structure was equipped with both

  18. Structural Health Monitoring Static Test of a Wind Turbine Blade: August 1999

    SciTech Connect

    Sundaresan, M. J.; Schulz, M. J.; Ghoshal, A.

    2002-03-01

    Structural health monitoring research is being performed by NCA&T, the NREL and Sandia Laboratories to develop a''Smart Blade'' with an embedded sensor system integrated into the blade by the manufacturer to continuously monitor the condition of the loading in the blade and reduce or prevent fatigue damage of the blade. This will reduce maintenance costs and improve the reliability of wind power.

  19. Study of compressible coherent structures, close to ion scales, in solar wind turbulence using Cluster data

    NASA Astrophysics Data System (ADS)

    Perrone, Denise; Alexandrova, Olga; Mangeney, André; Maksimovic, Milan; Rocoto, Virgile; Pantellini, Filippo; Zaslavsky, Arnaud; Issautier, Karine

    2015-04-01

    The interplanetary medium, a weakly collisional and fully turbulent medium, can be considered the best natural laboratory to study the dynamical behavior of turbulent plasmas. A fundamental question in solar wind plasma physics is whether, space plasma turbulence can be considered as a mixture of quasi-linear waves or if the turbulence is strong with formation of coherent structures responsible for the dissipation. Here we present an automatic method to identify compressible coherent structures using Morlet wavelet decomposition of magnetic signal from Cluster spacecraft and reconstruction of magnetic fluctuations in a selected scale range (0.033-0.2 Hz). Different kind of coherent structures have been detected: from soliton-like compressible structures to current sheet- or vortex-like alfvenic structures. A multi-satellite analysis, in order to characterize 3D geometry and propagation in plasma rest frame, reveals that these structures propagate quasi-perpendicular to the mean magnetic field, with finite velocity. Moreover, the spatial scales of coherent structures have been estimated: for the selected frequency range, the distribution of spatial scales is picked around ~30 ion Larmor radius or ion inertial length (~1200 km). Our observations in the solar wind can provide constraints on theoretical modeling of small-scale turbulence and dissipation in collisionless magnetized plasmas.

  20. Electronic Structure Determination of Pyridine N-Heterocyclic Carbene Iron Dinitrogen Complexes and Neutral Ligand Derivatives

    PubMed Central

    2015-01-01

    The electronic structures of pyridine N-heterocyclic dicarbene (iPrCNC) iron complexes have been studied by a combination of spectroscopic and computational methods. The goal of these studies was to determine if this chelate engages in radical chemistry in reduced base metal compounds. The iron dinitrogen example (iPrCNC)Fe(N2)2 and the related pyridine derivative (iPrCNC)Fe(DMAP)(N2) were studied by NMR, Mössbauer, and X-ray absorption spectroscopy and are best described as redox non-innocent compounds with the iPrCNC chelate functioning as a classical π acceptor and the iron being viewed as a hybrid between low-spin Fe(0) and Fe(II) oxidation states. This electronic description has been supported by spectroscopic data and DFT calculations. Addition of N,N-diallyl-tert-butylamine to (iPrCNC)Fe(N2)2 yielded the corresponding iron diene complex. Elucidation of the electronic structure again revealed the CNC chelate acting as a π acceptor with no evidence for ligand-centered radicals. This ground state is in contrast with the case for the analogous bis(imino)pyridine iron complexes and may account for the lack of catalytic [2π + 2π] cycloaddition reactivity. PMID:25328270

  1. Inverse structure functions in the canonical wind turbine array boundary layer

    NASA Astrophysics Data System (ADS)

    Viggiano, Bianca; Gion, Moira; Ali, Naseem; Tutkun, Murat; Cal, Raúl Bayoán

    2015-11-01

    Insight into the statistical behavior of the flow past an array of wind turbines is useful in determining how to improve power extraction from the overall available energy. Considering a wind tunnel experiment, hot-wire anemometer velocity signals are obtained at the centerline of a 3 x 3 canonical wind turbine array boundary layer. Two downstream locations are considered referring to the near- and far-wake, and 21 vertical points were acquired per profile. Velocity increments are used to quantify the ordinary and inverse structure functions at both locations and their relationship between the scaling exponents is noted. It is of interest to discern if there is evidence of an inverted scaling. The inverse structure functions will also be discussed from the standpoint of the proximity to the array. Observations will also address if inverted scaling exponents follow a power law behavior and furthermore, extended self-similarity of the second moment is used to obtain the scaling exponent of other moments. Inverse structure functions of moments one through eight are tested via probability density functions and the behavior of the negative moment is investigated as well. National Science Foundation-CBET-1034581.

  2. On the origin of variable structures in the winds of hot luminous stars

    NASA Astrophysics Data System (ADS)

    Michaux, Yannick J. L.; Moffat, Anthony F. J.; Chené, André-Nicolas; St-Louis, Nicole

    2014-05-01

    Examination of the temporal variability properties of several strong optical recombination lines in a large sample of Galactic Wolf-Rayet (WR) stars reveals possible trends, especially in the more homogeneous WC than the diverse WN subtypes, of increasing wind variability with cooler subtypes. This could imply that a serious contender for the driver of the variations is stochastic, magnetic subsurface convection associated with the 170 kK partial-ionization zone of iron, which should occupy a deeper and larger zone of greater mass in cooler WR subtypes. This empirical evidence suggests that the heretofore proposed ubiquitous driver of wind variability, radiative instabilities, may not be the only mechanism playing a role in the stochastic multiple small-scaled structures seen in the winds of hot luminous stars. In addition to small-scale stochastic behaviour, subsurface convection guided by a global magnetic field with localized emerging loops may also be at the origin of the large-scale corotating interaction regions as seen frequently in O stars and occasionally in the winds of their descendant WR stars.

  3. The changing wind structure of the WR/LBV star in HD 5980

    NASA Astrophysics Data System (ADS)

    Koenigsberger, Gloria

    2013-10-01

    HD 5980 is an extraordinary system of massive stars that is located in the Small Magellanic Cloud. It contains an eclipsing binary {P=19.3 d} consisting of a luminous blue variable {LBV} and its Wolf-Rayet {WR} companion. The LBV underwent a major eruptive event in 1994 during which its bolometric luminosity increased by a factor of 5 and it is currently approaching its minimum state of activity. The primary objective of this proposal is to determine the wind velocity and mass-loss rate of the LBV in its current state. With these observations and our earlier observations and analyses, HD 5980 offers the unprecedented opportunity of deriving all the fundamental parameters of an LBV system throughout its activity cycle, parameters which are required in order to constrain the sources of the instabilities that lead to the eruptive phenomena. To accomplish these goals, we request 2 HST orbits to observe HD 5980 with STIS in order to obtain one set of FUV MAMA and CCD spectra at the eclipse, when the LBV occults its WR companion.The study of HD 5980 and the UV spectrum that we propose to acquire are relevant to a broad range of problems including wind-wind collision phenomena, the formation of circumstellar structures powered by stellar winds and the evolution of supernova progenitors.

  4. Quaternary structure defines a large class of amyloid-β oligomers neutralized by sequestration

    PubMed Central

    Liu, Peng; Reed, Miranda N.; Kotilinek, Linda A.; Grant, Marianne K.O.; Forster, Colleen L.; Qiang, Wei; Shapiro, Samantha L.; Reichl, John H.; Chiang, Angie C.A.; Jankowsky, Joanna L.; Wilmot, Carrie M.; Cleary, James P.; Zahs, Kathleen R.; Ashe, Karen H.

    2015-01-01

    Summary The accumulation of amyloid-β (Aβ) as amyloid fibrils and toxic oligomers is an important step in the development of Alzheimer's disease (AD). However, there are numerous potentially toxic oligomers and little is known about their neurological effects when generated in the living brain. Here, we show that Aβ oligomers can be assigned to one of at least two classes (Type 1 and Type 2) based on their temporal, spatial and structural relationships to amyloid fibrils. The Type 2 oligomers are related to amyloid fibrils and represent the majority of oligomers generated in vivo, but remain confined to the vicinity of amyloid plaques and do not impair cognition at levels relevant to AD. Type 1 oligomers are unrelated to amyloid fibrils and may have greater potential to cause global neural dysfunction in AD because they are dispersed. These results refine our understanding of the pathogenicity of Aβ oligomers in vivo. PMID:26051935

  5. Recent improvements in our knowledge of neutral atmosphere structure from satellite drag measurements

    NASA Technical Reports Server (NTRS)

    Roemer, M.

    1974-01-01

    Observational results on the density in the thermosphere and lower exosphere (i.e., within the altitude range from about 150 to about 1000 km) are discussed in this paper. Most observational results on total gas density were obtained from orbital drag and more recently also from in-situ drag analysis. The primary parameter measured is atmospheric density, with temperature as a secondary structural parameter deduced with the help of theory and/or atmospheric models. Both the merits and shortcomings of the drag analysis method are outlined in view of a comparison of temperature deduced from total density and kinetic gas temperature measured by incoherent scatter. Recent improvements of our knowledge of the known density variations are presented.

  6. Synthetic magnetic field effects on neutral bosonic condensates in quasi-three-dimensional anisotropic layered structures

    SciTech Connect

    Zaleski, T. A.; Polak, T. P.

    2011-02-15

    We discuss a system of dilute Bose gas confined in a layered structure of stacked square lattices (slab geometry). A derived phase diagram reveals a nonmonotonic dependence of the ratio of tunneling to on-site repulsion on the artificial magnetic field applied to the system. The effect is reduced when more layers are added, which mimics a two- to quasi-three-dimensional geometry crossover. Furthermore, we establish a correspondence between anisotropic infinite (quasi-three-dimensional) and isotropic finite (slab geometry) systems that share exactly the same critical values, which can be an important clue for choosing experimental setups that are less demanding, but still leading to the identical results. Finally, we show that the properties of the ideal Bose gas in a three-dimensional optical lattice can be closely mimicked by finite (slab) systems when the number of two-dimensional layers is larger than 10 for isotropic interactions, or even less when the layers are weakly coupled.

  7. Structural Analysis of Human and Macaque Monoclonal Antibodies 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120

    SciTech Connect

    B Spurrier; J Sampson; M Totrov; H Li; T ONeal; C Williams; J Robinson; M Gorny; S Zolla-Pazner; X Kong

    2011-12-31

    The quaternary neutralizing epitope (QNE) of HIV-1 gp120 is preferentially expressed on the trimeric envelope spikes of intact HIV virions, and QNE-specific monoclonal antibodies (mAbs) potently neutralize HIV-1. Here, we present the crystal structures of the Fabs of human mAb 2909 and macaque mAb 2.5B. Both mAbs have long beta hairpin CDR H3 regions >20 {angstrom} in length that are each situated at the center of their respective antigen-binding sites. Computational analysis showed that the paratopes include the whole CDR H3, while additional CDR residues form shallow binding pockets. Structural modeling suggests a way to understand the configuration of QNEs and the antigen-antibody interaction for QNE mAbs. Our data will be useful in designing immunogens that may elicit potent neutralizing QNE Abs.

  8. Coordination Complexes of a Neutral 1,2,4-Benzotriazinyl Radical Ligand: Synthesis, Molecular and Electronic Structures, and Magnetic Properties.

    PubMed

    Morgan, Ian S; Mansikkamäki, Akseli; Zissimou, Georgia A; Koutentis, Panayiotis A; Rouzières, Mathieu; Clérac, Rodolphe; Tuononen, Heikki M

    2015-10-26

    A series of d-block metal complexes of the recently reported coordinating neutral radical ligand 1-phenyl-3-(pyrid-2-yl)-1,4-dihydro-1,2,4-benzotriazin-4-yl (1) was synthesized. The investigated systems contain the benzotriazinyl radical 1 coordinated to a divalent metal cation, Mn(II) , Fe(II) , Co(II) , or Ni(II) , with 1,1,1,5,5,5-hexafluoroacetylacetonato (hfac) as the auxiliary ligand of choice. The synthesized complexes were fully characterized by single-crystal X-ray diffraction, magnetic susceptibility measurements, and electronic structure calculations. The complexes [Mn(1)(hfac)2 ] and [Fe(1)(hfac)2 ] displayed antiferromagnetic coupling between the unpaired electrons of the ligand and the metal cation, whereas the interaction was found to be ferromagnetic in the analogous Ni(II) complex [Ni(1)(hfac)2 ]. The magnetic properties of the complex [Co(1)(hfac)2 ] were difficult to interpret owing to significant spin-orbit coupling inherent to octahedral high-spin Co(II) metal ion. As a whole, the reported data clearly demonstrated the favorable coordinating properties of the radical 1, which, together with its stability and structural tunability, make it an excellent new building block for establishing more complex metal-radical architectures with interesting magnetic properties. PMID:26493885

  9. Structure and spectroscopic properties of neutral and cationic tetratomic [C,H,N,Zn] isomers: A theoretical study

    SciTech Connect

    Redondo, Pilar; Largo, Antonio; Vega-Vega, Álvaro; Barrientos, Carmen

    2015-05-14

    The structure and spectroscopic parameters of the most relevant [C,H,N,Zn] isomers have been studied employing high-level quantum chemical methods. For each isomer, we provide predictions for their molecular structure, thermodynamic stabilities as well as vibrational and rotational spectroscopic parameters which could eventually help in their experimental detection. In addition, we have carried out a detailed study of the bonding situations by means of a topological analysis of the electron density in the framework of the Bader’s quantum theory of atoms in molecules. The analysis of the relative stabilities and spectroscopic parameters suggests two linear isomers of the neutral [C,H,N,Zn] composition, namely, cyanidehydridezinc HZnCN ({sup 1}Σ) and hydrideisocyanidezinc HZnNC ({sup 1}Σ), as possible candidates for experimental detections. For the cationic [C,H,N,Zn]{sup +} composition, the most stable isomers are the ion-molecule complexes arising from the direct interaction of the zinc cation with either the nitrogen or carbon atom of either hydrogen cyanide or hydrogen isocyanide, namely, HCNZn{sup +} ({sup 2}Σ) and HCNZn{sup +} ({sup 2}Σ)

  10. DIFFUSION IN THE VICINITY OF STANDARD-DESIGN NUCLEAR POWER PLANTS-I. WIND-TUNNEL EVALUATION OF DIFFUSIVE CHARACTERISTICS OF A SIMULATED SUBURBAN NEUTRAL ATMOSPHERIC BOUNDARY LAYER

    EPA Science Inventory

    A large meteorological wind tunnel was used to simulate a suburban atmospheric boundary layer. The model-prototype scale was 1:300 and the roughness length was approximately 1.0 m full scale. The model boundary layer simulated full scale dispersion from ground-level and elevated ...

  11. Supramolecular structure of enterobacterial wild-type lipopolysaccharides (LPS), fractions thereof, and their neutralization by Pep19-2.5.

    PubMed

    Brandenburg, Klaus; Heinbockel, Lena; Correa, Wilmar; Fukuoka, Satoshi; Gutsmann, Thomas; Zähringer, Ulrich; Koch, Michel H J

    2016-04-01

    Lipopolysaccharides (LPS) belong to the strongest immune-modulating compounds known in nature, and are often described as pathogen-associated molecular patterns (PAMPs). In particular, at higher concentrations they are responsible for sepsis and the septic shock syndrome associated with high lethality. Since most data are indicative that LPS aggregates are the bioactive units, their supramolecular structures are considered to be of outmost relevance for deciphering the molecular mechanisms of its bioactivity. So far, however, most of the data available addressing this issue, were published only for the lipid part (lipid A) and the core-oligosaccharide containing rough LPS, representing the bioactive unit. By contrast, it is well known that most of the LPS specimen identified in natural habitats contain the smooth-form (S-form) LPS, which carry additionally a high-molecular polysaccharide (O-chain). To fill this lacuna and going into a more natural system, here various wild-type (smooth form) LPS including also some LPS fractions were investigated by small-angle X-ray scattering with synchrotron radiation to analyze their aggregate structure. Furthermore, the influence of a recently designed synthetic anti-LPS peptide (SALP) Pep19-2.5 on the aggregate structure, on the binding thermodynamics, and on the cytokine-inducing activity of LPS were characterized, showing defined aggregate changes, high affinity binding and inhibition of cytokine secretion. The data obtained are suitable to refine our view on the preferences of LPS for non-lamellar structures, representing the highest bioactive forms which can be significantly influenced by the binding with neutralizing peptides such as Pep19-2.5. PMID:26828112

  12. Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin.

    PubMed

    Hjorth, Christian Fogt; Norrman, Mathias; Wahlund, Per-Olof; Benie, Andrew J; Petersen, Bent O; Jessen, Christian M; Pedersen, Thomas Å; Vestergaard, Kirsten; Steensgaard, Dorte B; Pedersen, Jan Skov; Naver, Helle; Hubálek, František; Poulsen, Christian; Otzen, Daniel

    2016-04-01

    A specific covalently linked dimeric species of insulin high molecular weight products (HMWPs), formed during prolonged incubation of a neutral pharmaceutical formulation of human insulin, were characterized in terms of tertiary structure, self-association, biological activity, and fibrillation properties. The dimer was formed by a covalent link between A21Asn and B29Lys. It was analyzed using static and dynamic light scattering and small-angle X-ray scattering to evaluate its self-association behavior. The tertiary structure was obtained using nuclear magnetic resonance and X-ray crystallography. The biological activity of HMWP was determined using 2 in vitro assays, and its influence on fibrillation was investigated using Thioflavin T assays. The dimer's tertiary structure was nearly identical to that of the noncovalent insulin dimer, and it was able to form hexamers in the presence of zinc. The dimer exhibited reduced propensity for self-association in the absence of zinc but significantly postponed the onset of fibrillation in insulin formulations. Consistent with its dimeric state, the tested species of HMWP showed little to no biological activity in the used assays. This study is the first detailed characterization of a specific type of human insulin HMWP formed during storage of a marketed pharmaceutical formulation. These results indicate that this specific type of HMWP is unlikely to antagonize the physical stability of the formulation, as HMWP retained a tertiary structure similar to the noncovalent dimer and participated in hexamer assembly in the presence of zinc. In addition, increasing amounts of HMWP reduce the rate of insulin fibrillation. PMID:26921119

  13. Optimal Neutralization of Centruroides noxius Venom Is Understood through a Structural Complex between Two Antibody Fragments and the Cn2 Toxin.

    PubMed

    Riaño-Umbarila, Lidia; Ledezma-Candanoza, Luis M; Serrano-Posada, Hugo; Fernández-Taboada, Guillermo; Olamendi-Portugal, Timoteo; Rojas-Trejo, Sonia; Gómez-Ramírez, Ilse V; Rudiño-Piñera, Enrique; Possani, Lourival D; Becerril, Baltazar

    2016-01-22

    The current trend of using recombinant antibody fragments in research to develop novel antidotes against scorpion stings has achieved excellent results. The polyclonal character of commercial antivenoms, obtained through the immunization of animals and which contain several neutralizing antibodies that recognize different epitopes on the toxins, guarantees the neutralization of the venoms. To avoid the use of animals, we aimed to develop an equivalent recombinant antivenom composed of a few neutralizing single chain antibody fragments (scFvs) that bind to two different epitopes on the scorpion toxins. In this study, we obtained scFv RU1 derived from scFv C1. RU1 showed a good capacity to neutralize the Cn2 toxin and whole venom of the scorpion Centruroides noxius. Previously, we had produced scFv LR, obtained from a different parental fragment (scFv 3F). LR also showed a similar neutralizing capacity. The simultaneous administration of both scFvs resulted in improved protection, which was translated as a rapid recovery of previously poisoned animals. The crystallographic structure of the ternary complex scFv LR-Cn2-scFv RU1 allowed us to identify the areas of interaction of both scFvs with the toxin, which correspond to non-overlapping sites. The epitope recognized by scFv RU1 seems to be related to a greater efficiency in the neutralization of the whole venom. In addition, the structural analysis of the complex helped us to explain the cross-reactivity of these scFvs and how they neutralize the venom. PMID:26589800

  14. Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1

    SciTech Connect

    Pejchal, Robert; Walker, Laura M.; Stanfield, Robyn L.; Phogat, Sanjay K.; Koff, Wayne C.; Poignard, Pascal; Burton, Dennis R.; Wilson, Ian A.

    2010-11-15

    Development of an effective vaccine against HIV-1 will likely require elicitation of broad and potent neutralizing antibodies against the trimeric surface envelope glycoprotein (Env). Monoclonal antibodies (mAbs) PG9 and PG16 neutralize {approx}80% of HIV-1 isolates across all clades with extraordinary potency and target novel epitopes preferentially expressed on Env trimers. As these neutralization properties are ideal for a vaccine-elicited antibody response to HIV-1, their structural basis was investigated. The crystal structure of the antigen-binding fragment (Fab) of PG16 at 2.5 {angstrom} resolution revealed its unusually long, 28-residue, complementarity determining region (CDR) H3 forms a unique, stable subdomain that towers above the antibody surface. A 7-residue 'specificity loop' on the 'hammerhead' subdomain was identified that, when transplanted from PG16 to PG9 and vice versa, accounted for differences in the fine specificity and neutralization of these two mAbs. The PG16 electron density maps also revealed that a CDR H3 tyrosine was sulfated, which was confirmed for both PG9 (doubly) and PG16 (singly) by mass spectral analysis. We further showed that tyrosine sulfation plays a role in binding and neutralization. An N-linked glycan modification is observed in the variable light chain, but not required for antigen recognition. Further, the crystal structure of the PG9 light chain at 3.0 {angstrom} facilitated homology modeling to support the presence of these unusual features in PG9. Thus, PG9 and PG16 use unique structural features to mediate potent neutralization of HIV-1 that may be of utility in antibody engineering and for high-affinity recognition of a variety of therapeutic targets.

  15. A novel structure of transmission line pulse transformer with mutually coupled windings.

    PubMed

    Yu, Binxiong; Su, Jiancang; Li, Rui; Zhao, Liang; Zhang, Xibo; Wang, Junjie

    2014-03-01

    A novel structure of transmission line transformer (TLT) with mutually coupled windings is described in this paper. All transmission lines except the first stage of the transformer are wound on a common ferrite core for the TLT with this structure. A referral method was introduced to analyze the TLT with this structure, and an analytic expression of the step response was derived. It is shown that a TLT with this structure has a significantly slower droop rate than a TLT with other winding structures and the number of ferrite cores needed is largely reduced. A four-stage TLT with this structure was developed, whose input and output impedance were 4.2 Ω and 67.7 Ω, respectively. A frequency response test of the TLT was carried out. The test results showed that pulse response time of the TLT is several nanoseconds. The TLT described in this paper has the potential to be used as a rectangle pulse transformer with very fast response time. PMID:24689623

  16. Synthesis and structures of neutral and cationic rac-(ethylenebis(tetrahydroindenyl))zirconium(IV) benzyl complexes

    SciTech Connect

    Jordan, R.F.; LaPointe, R.E.; Baenziger, N.; Hinch, G.D. )

    1990-05-01

    Reaction of rac-(ethylenebis(tetrahydroindenyl))ZrCl{sub 2} (1) with 2 equiv of K(CH{sub 2}Ph) produces the dibenzyl complex (ethylenebis(tetrahydroindenyl))Zr(CH{sub 2}Ph){sub 2} (2). Reaction of 2 with ((C{sub 5}H{sub 4}Me){sub 2}Fe)(BPh{sub 4}) yields the cationic complex ((ethylenebis(tetrahydroindenyl))Zr(CH{sub 2}Ph)(THF))(BPh{sub 4}) (3). In CH{sub 3}CN solvent, 3 undergoes ligand substitution to yield ((ethylenebis(tetrahydroindenyl))Zr({eta}{sup 2}-CH{sub 2}Ph)(CH{sub 3}CN))(BPh{sub 4}) (4). The structures of 2 and 4 have been determined by X-ray diffraction. Complex 2 crystallizes in space group Pbcn with a = 10.008 (3) {angstrom}, b = 14.895 (4) {angstrom}, c = 17.532 (6) {angstrom}, V = 2,613.5 (2.4) {angstrom}{sup 3}, and Z = 4. Complex 4 crystallizes in space group P1 with a = 12.300 (2) {angstrom}, b = 12.493 (2) {angstrom}, c = 16.633 (3) {angstrom}, {alpha} = 84.61 (1){degree}, {beta} = 71.18 (1){degree}, {gamma} = 69.42 (1){degree}, V = 2,264.1 (9) {angstrom}{sup 3}, and Z = 2.

  17. Surface solitary waves and solitons. [in solar atmosphere and solar wind magnetic structure

    NASA Technical Reports Server (NTRS)

    Hollweg, J. V.; Roberts, B.

    1984-01-01

    The solar atmosphere and solar wind are magnetically structured. The structuring can include tangential discontinuities, which can support surface waves. Such waves can be dispersive. This means that dispersion and nonlinearity can balance in such a way that solitary waves (or solitons) can result. This general point is illustrated by a two-dimensional nonlinear analysis which explicitly demonstrates the presence of long-wavelength solitary waves propagating on tangential discontinuities. If the waves are only weakly nonlinear, then they obey the Korteweg-de Vries equation and are true solitons.

  18. Differential Velocity between Solar Wind Protons and Alpha Particles in Pressure Balance Structures

    NASA Technical Reports Server (NTRS)

    Yamauchi, Yohei; Suess, Steven T.; Steinberg, John T.; Sakurai, Takashi

    2004-01-01

    Pressure balance structures (PBSs) are a common high-plasma beta feature in high-latitude, high-speed solar wind. They have been proposed as remnants of coronal plumes. If true, they should reflect the observation that plumes are rooted in unipolar magnetic flux concentrations in the photosphere and are heated as oppositely directed flux is advected into and reconnects with the flux concentration. A minimum variance analysis (MVA) of magnetic discontinuities in PBSs showed there is a larger proportion of tangential discontinuities than in the surrounding high-speed wind, supporting the hypothesis that plasmoids or extended current sheets are formed during reconnection at the base of plumes. To further evaluate the character of magnetic field discontinuities in PBSs, differential streaming between alpha particles and protons is analyzed here for the same sample of PBSs used in the MVA. Alpha particles in high-speed wind generally have a higher radial flow speed than protons. However, if the magnetic field is folded back on itself, as in a large-amplitude Alfven wave, alpha particles will locally have a radial flow speed less than protons. This characteristic is used here to distinguish between folded back magnetic fields (which would contain rotational discontinuities) and tangential discontinuities using Ulysses high-latitude, high-speed solar wind data. The analysis indicates that almost all reversals in the radial magnetic field in PBSs are folded back field lines. This is found to also be true outside PBSs, supporting existing results for typical high-speed, high-latitude wind. There remains a small number of cases that appear not to be folds in the magnetic field and which may be flux tubes with both ends rooted in the Sun. The distinct difference in MVA results inside and outside PBSs remains unexplained.

  19. Differential Velocity Between Solar Wind Protons and Alpha Particles in Pressure Balance Structures

    NASA Technical Reports Server (NTRS)

    Yamauchi, Y.; Suess, S. T.; Steinberg, J. T.; Sakurai, T.

    2003-01-01

    Pressure balance structures (PBSs) are a common high plasma beta feature in high latitude, high speed solar wind. They have been proposed as remnants of coronal plumes. If true, they should reflect the observation that plumes are rooted in unipolar magnetic flux concentrations in the photosphere and are heated as oppositely directed flux is advected into and reconnects with the flux concentration. A minimum variance analysis (MVA) of magnetic discontinuities in PBSs showed there is a larger proportion of tangential discontinuities than in the surrounding high speed wind, supporting the hypothesis that plasmoids or extended current sheets are formed during reconnection at the base of plumes. To further evaluate the character of magnetic field discontinuities in PBSs, differential streaming between alpha particles and protons is analyzed here for the same sample of PBSs used in the MVA. Alpha particles in high speed wind generally have a higher radial flow speed than protons. However, if the magnetic field is folded back on itself, as in a large amplitude Alfven wave, alpha particles will locally have a radial flow speed less than protons. This characteristic is used here to distinguish between folded back magnetic fields (which would contain rotational discontinuities) and tangential discontinuities using Ulysses high latitude, high speed solar wind data. The analysis indicates that almost all reversals in the radial magnetic field in PBSs are folded back field lines. This is found to also be true outside PBSs, supporting existing results for typical high speed, high latitude wind. There remains a small number of cases that appear not to be folds in the magnetic field and which may be flux tubes with both ends rooted in the Sun. The distinct difference in MVA results inside and outside PBSs remains unexplained.

  20. Structure and dynamics of the accretion process and wind in TW Hya

    SciTech Connect

    Dupree, A. K.; Brickhouse, N. S.; Cranmer, S. R.; Berlind, P.; Strader, Jay; Smith, Graeme H.

    2014-07-01

    Time-domain spectroscopy of the classical accreting T Tauri star, TW Hya, covering a decade and spanning the far UV to the near-infrared spectral regions can identify the radiation sources, the atmospheric structure produced by accretion, and properties of the stellar wind. On timescales from days to years, substantial changes occur in emission line profiles and line strengths. Our extensive time-domain spectroscopy suggests that the broad near-IR, optical, and far-uv emission lines, centered on the star, originate in a turbulent post-shock region and can undergo scattering by the overlying stellar wind as well as some absorption from infalling material. Stable absorption features appear in Hα, apparently caused by an accreting column silhouetted in the stellar wind. Inflow of material onto the star is revealed by the near-IR He I 10830 Å line, and its free-fall velocity correlates inversely with the strength of the post-shock emission, consistent with a dipole accretion model. However, the predictions of hydrogen line profiles based on accretion stream models are not well-matched by these observations. Evidence of an accelerating warm to hot stellar wind is shown by the near-IR He I line, and emission profiles of C II, C III, C IV, N V, and O VI. The outflow of material changes substantially in both speed and opacity in the yearly sampling of the near-IR He I line over a decade. Terminal outflow velocities that range from 200 km s{sup –1} to almost 400 km s{sup –1} in He I appear to be directly related to the amount of post-shock emission, giving evidence for an accretion-driven stellar wind. Calculations of the emission from realistic post-shock regions are needed.

  1. WIND STRUCTURE AND LUMINOSITY VARIATIONS IN THE WOLF-RAYET/LUMINOUS BLUE VARIABLE HD 5980

    SciTech Connect

    Georgiev, Leonid; Koenigsberger, Gloria; Hillier, D. John; Morrell, Nidia; Gamen, Roberto E-mail: gloria@astro.unam.mx

    2011-12-15

    Over the past 40 years, the massive luminous blue variable/Wolf-Rayet system HD 5980 in the Small Magellanic Cloud (SMC) has undergone a long-term S Doradus-type variability cycle and two brief and violent eruptions in 1993 and 1994. In this paper we analyze a collection of UV and optical spectra obtained between 1979 and 2009 and perform CMFGEN model fits to spectra of 1994, 2000, 2002, and 2009. The results are as follows: (1) the long-term S Dor-type variability is associated with changes of the hydrostatic radius; (2) the 1994 eruption involved changes in its bolometric luminosity and wind structure; (3) the emission-line strength, the wind velocity, and the continuum luminosity underwent correlated variations in the sense that a decreasing V{sub {infinity}} is associated with increasing emission line and continuum levels; and (4) the spectrum of the third star in the system (Star C) is well fit by a T{sub eff} = 32 K model atmosphere with SMC chemical abundances. For all epochs, the wind of the erupting star is optically thick at the sonic point and is thus driven mainly by the continuum opacity. We speculate that the wind switches between two stable regimes driven by the 'hot' (during the eruption) and the 'cool' (post-eruption) iron opacity bumps as defined by Lamers and Nugis and Graefener and Hamann, and thus the wind may undergo a bi-stability jump of a different nature from that which occurs in OB stars.

  2. Propagation of the 12 May 1997 interplanetary coronal mass ejection in evolving solar wind structures

    NASA Astrophysics Data System (ADS)

    Odstrcil, D.; Pizzo, V. J.; Arge, C. N.

    2005-02-01

    Recently, we simulated the 12 May 1997 coronal mass ejection (CME) event with a numerical three-dimensional magnetohydrodynamic model (Odstrcil et al., 2004), in which the background solar wind was determined from the Science Applications International Corporation (SAIC) coronal model (Riley et al., 2001) and the transient disturbance was determined from the cone model (Zhao et al., 2002). Although we reproduced with some fidelity the arrival of the shock and interplanetary CME at Earth, detailed analysis of the simulations showed a poorly defined shock and discrepancies in the standoff distance between the shock and the driving ejecta and in the inclination of the shock with respect to the Sun-Earth line. In this paper, we investigate these problems in more detail. First, we use an alternative coronal outflow model, the so-called Wang-Sheeley-Arge-Mount Wilson Observatory (WSA-MWO) model (Arge and Pizzo, 2000; Arge et al., 2002; Arge et al., 2004), to assess the effect of using synoptic, full rotation coronal maps that differ in method of preparation. Second, we investigate how differences in the presumed evolution of the coronal stream structure affect the propagation of the disturbance. We incorporate two time-dependent boundary conditions for the ambient solar wind as determined by the WSA model, one derived from pseudo daily updated maps and one derived from artificially modified full rotation maps. Numerical results from these different scenarios are compared with solar wind observations at Earth. We find that heliospheric simulations with the SAIC and WSA full rotation models provide qualitatively similar parameters of the background solar wind and transient disturbances at Earth. Improved agreement with the observations is achieved by artificially modified maps that simulate the rapid displacement of the coronal hole boundary after the CME eruption. We also consider how multipoint temporal profiles of solar wind parameters and multiperspective synthetic

  3. A numerical investigation of the wake structure of vertical axis wind turbines

    NASA Astrophysics Data System (ADS)

    Balaras, Elias; Posa, Antonio; Leftwich, Megan

    2014-11-01

    Recent field-testing has shown that vertical axis wind turbines (VAWT) in wind farm configurations have the potential to reach higher power densities, when compared to the more widespread horizontal axis turbines. A critical component in achieving this goal is a good understanding of the wake structure and how it is influenced by operating conditions. In the present study the Large-Eddy Simulation technique is adopted to characterize the wake of a small vertical axis wind turbine and to explore its dependence on the value of its Tip Speed Ratio (TSR). It will be shown that its wake significantly differs from that of a spinning cylinder, often adopted to model this typology of machines: the displacement of the momentum deficit towards the windward side follows the same behavior, but turbulence is higher on the leeward side. An initial increase of the momentum deficit is observed moving downstream, with central peaks in the core of the near wake for both momentum and turbulent kinetic energy, especially at lower TSRs. No back-flow is produced downstream of the turbine. The interaction between blades is stronger at higher values of the TSR, while the production of coherent structures is enhanced at lower TSRs, with large rollers populating the leeward side of the wake.

  4. Spatial Variances of Wind Fields and Their Relation to Second-Order Structure Functions and Spectra

    NASA Astrophysics Data System (ADS)

    King, G. P.; Vogelzang, J.; Stoffelen, A.; Portabella, M.

    2014-12-01

    Kinetic energy variance as a function of spatial scale for wind fields is commonly estimated either using second-order structure functions (in the spatial domain) or by spectral analysis (in the frequency domain). It will be demonstrated that neither spectra nor second-order structure functions offer a good representation of the variance as a function of scale. These difficulties can be circumvented by using a statistical quantity called spatial variance. It combines the advantages of spectral analysis and spatial statistics. In particular, when applied to observations, spatial variances have a clear interpretation and are tolerant for missing data. They can be related to second-order structure functions, both for discrete and continuous data. For data sets without missing points the relation is statistically exact. Spatial variances can also be Fourier transformed to yield a relation with spectra. The flexibility of spatial variances is used to study various sampling strategies, and to compare them with second-order structure functions and spectral variances. It is shown that the spectral sampling strategy is not seriously biased to calm conditions for scatterometer ocean surface vector winds, and that one-fifth of the second-order structure function value is a good proxy for the cumulative variance.

  5. Associations between Small-scale Structure in Local Galactic Neutral Hydrogen and in the Cosmic Microwave Background Observed by PLANCK

    NASA Astrophysics Data System (ADS)

    Verschuur, Gerrit L.

    2015-11-01

    High-resolution galactic neutral hydrogen (HI) data obtained with the Green Bank Telescope (GBT) over 56 square degrees of sky around l = 132°, b = 25° are compared with small-scale structure in the Cosmic Microwave Background observed by PLANCK, specifically at 143 and 857 GHz, as well as with 100 μm observations from the IRIS survey. The analysis uses data in 13 2° × 2° sub-areas found in the IRSA database at IPAC. The results confirm what has been reported previously; nearby galactic HI features and high-frequency continuum sources believed to be cosmological are in fact clearly associated. While several attempts strongly suggest that the associations are statistically significant, the key to understanding the phenomenon lies in the fact that in any given area HI is associated with cirrus dust at certain HI velocities and with 143 GHz features at different velocities. At the same time, for the 13 sub-areas studied, there is very little overlap between the dust and 143 GHz features. The data do not imply that the HI itself gives rise to the high-frequency continuum emission. Rather, they appear to indicate undiagnosed brightness enhancements indirectly associated with the HI. If low density interstellar electrons concentrated into clumps, or observed in directions where their integrated line-of-sight column densities are greater than the background in a manner similar to the phenomena that give rise to structure in diffuse HI structure, they will profoundly affect attempts to create a foreground electron mask used for processing PLANCK as well as WMAP data.

  6. Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody

    PubMed Central

    Xiong, Xiaoli; Corti, Davide; Liu, Junfeng; Pinna, Debora; Foglierini, Mathilde; Calder, Lesley J.; Martin, Stephen R.; Lin, Yi Pu; Walker, Philip A.; Collins, Patrick J.; Monne, Isabella; Suguitan, Amorsolo L.; Santos, Celia; Temperton, Nigel J.; Subbarao, Kanta; Lanzavecchia, Antonio; Gamblin, Steven J.; Skehel, John J.

    2015-01-01

    H5N1 avian influenza viruses remain a threat to public health mainly because they can cause severe infections in humans. These viruses are widespread in birds, and they vary in antigenicity forming three major clades and numerous antigenic variants. The most important features of the human monoclonal antibody FLD194 studied here are its broad specificity for all major clades of H5 influenza HAs, its high affinity, and its ability to block virus infection, in vitro and in vivo. As a consequence, this antibody may be suitable for anti-H5 therapy and as a component of stockpiles, together with other antiviral agents, for health authorities to use if an appropriate vaccine was not available. Our mutation and structural analyses indicate that the antibody recognizes a relatively conserved site near the membrane distal tip of HA, near to, but distinct from, the receptor-binding site. Our analyses also suggest that the mechanism of infectivity neutralization involves prevention of receptor recognition as a result of steric hindrance by the Fc part of the antibody. Structural analyses by EM indicate that three Fab fragments are bound to each HA trimer. The structure revealed by X-ray crystallography is of an HA monomer bound by one Fab. The monomer has some similarities to HA in the fusion pH conformation, and the monomer’s formation, which results from the presence of isopropanol in the crystallization solvent, contributes to considerations of the process of change in conformation required for membrane fusion. PMID:26170284

  7. Structural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41

    SciTech Connect

    Gustchina, Elena; Li, Mi; Louis, John M.; Anderson, D.Eric; Lloyd, John; Frisch, Christian; Bewley, Carole A.; Gustchina, Alla; Wlodawer, Alexander; Clore, G.Marius

    2010-12-03

    The conserved internal trimeric coiled-coil of the N-heptad repeat (N-HR) of HIV-1 gp41 is transiently exposed during the fusion process by forming a pre-hairpin intermediate, thus representing an attractive target for the design of fusion inhibitors and neutralizing antibodies. In previous studies we reported a series of broadly neutralizing mini-antibodies derived from a synthetic naive human combinatorial antibody library by panning against a mimetic of the trimeric N-HR coiled coil, followed by affinity maturation using targeted diversification of the CDR-H2 loop. Here we report crystal structures of the N-HR mimetic 5-Helix with two Fabs that represent the extremes of this series: Fab 8066 is broadly neutralizing across a wide panel of B and C type HIV-1 viruses, whereas Fab 8062 is non-neutralizing. The crystal structures reveal important differences in the conformations of the CDR-H2 loops in the complexes that propagate into other regions of the antigen-antibody interface, and suggest that both neutralization properties and affinity for the target can be attributed, at least in part, to the differences in the interactions of the CDR-H2 loops with the antigen. Furthermore, modeling of the complex of an N-HR trimer with three Fabs suggests that the CDR-H2 loop may be involved in close intermolecular contacts between neighboring antibody molecules, and that such contacts may hinder the formation of complexes between the N-HR trimer and more than one antibody molecule depending on the conformation of the bound CDR-H2 loop which is defined by its interactions with antigen. Comparison with the crystal structure of the complex of 5-Helix with another neutralizing monoclonal antibody known as D5, derived using an entirely different antibody library and panning procedure, reveals remarkable convergence in the optimal sequence and conformation of the CDR-H2 loop.

  8. Seismic analysis of offshore wind turbines on bottom-fixed support structures.

    PubMed

    Alati, Natale; Failla, Giuseppe; Arena, Felice

    2015-02-28

    This study investigates the seismic response of a horizontal axis wind turbine on two bottom-fixed support structures for transitional water depths (30-60 m), a tripod and a jacket, both resting on pile foundations. Fully coupled, nonlinear time-domain simulations on full system models are carried out under combined wind-wave-earthquake loadings, for different load cases, considering fixed and flexible foundation models. It is shown that earthquake loading may cause a significant increase of stress resultant demands, even for moderate peak ground accelerations, and that fully coupled nonlinear time-domain simulations on full system models are essential to capture relevant information on the moment demand in the rotor blades, which cannot be predicted by analyses on simplified models allowed by existing standards. A comparison with some typical design load cases substantiates the need for an accurate seismic assessment in sites at risk from earthquakes. PMID:25583865

  9. Detection of small-scale structures in the dissipation regime of solar-wind turbulence.

    PubMed

    Perri, S; Goldstein, M L; Dorelli, J C; Sahraoui, F

    2012-11-01

    Recent observations of the solar wind have pointed out the existence of a cascade of magnetic energy from the scale of the proton Larmor radius ρ(p) down to the electron Larmor radius ρ(e) scale. In this Letter we study the spatial properties of magnetic field fluctuations in the solar wind and find that at small scales the magnetic field does not resemble a sea of homogeneous fluctuations, but rather a two-dimensional plane containing thin current sheets and discontinuities with spatial sizes ranging from l >/~ ρ(p) down to ρ(e) and below. These isolated structures may be manifestations of intermittency that localize sites of turbulent dissipation. Studying the relationship between turbulent dissipation, reconnection, and intermittency is crucial for understanding the dynamics of laboratory and astrophysical plasmas. PMID:23215371

  10. The turbulence structure of katabatic flows below and above wind-speed maximum

    NASA Astrophysics Data System (ADS)

    Grachev, Andrey; Leo, Laura; Di Sabatino, Silvana; Fernando, Harindra; Pardyjak, Eric; Fairall, Christopher

    2015-04-01

    Measurements of atmospheric small-scale turbulence made over the complex-terrain at the US Army Dugway Proving Grounds in Utah during the Mountain Terrain Atmospheric Modeling and Observations (MATERHORN) Program are used to describe the turbulence structure of katabatic flows. Turbulent and mean meteorological data were continuously measured at multiple levels (up to seven) on four towers deployed along East lower slope (2-4 degrees) of Granite Mountain. The multi-level, multi-tower observations obtained during a 30-day long MATERHORN-Fall field campaign in September-October 2102 allow studying temporal and spatial structure of nocturnal slope flows in detail. In this study, we focus on the various statistics (fluxes, variances, spectra, cospectra, etc.) of the small-scale turbulence of katabatic winds. Observed vertical profiles of velocity, turbulent fluxes, and other quantities show steep gradients near the surface but in the layer above the slope jet these variables vary with height more slowly than near the surface. It is found that vertical momentum flux and horizontal heat (buoyancy) flux in a slope-following coordinate system change their sign below and above the wind maximum of a katabatic flow. The vertical momentum flux is directed downward (upward) whereas the horizontal heat flux is downslope (upslope) below (above) the wind maximum. Our study, therefore, suggests that a position of the jet speed maximum can be derived from linear interpolation between positive and negative values of the momentum flux (or the horizontal heat flux) and determination of a height where a flux becomes zero. It is shown that the standard deviations of all wind speed components (and therefore the turbulent kinetic energy) and the dissipation rate of turbulent kinetic energy have a local minimum, whereas the standard deviation of air temperature has an absolute maximum at the height of wind speed maximum. We report several cases when the destructive effect of vertical heat

  11. Exploring the connections between dark spot dynamics and zonal wind structure on Uranus

    NASA Astrophysics Data System (ADS)

    Le Beau, Raymond P.; Palotai, Csaba

    2015-11-01

    The past several years have witnessed new observations revealing more clouds and long-lived features in the atmosphere of Uranus. Each new set of images provides new cloud-tracking data and the opportunity to assess the structure of the zonal winds on Uranus. This has led to a sequence of fits for the Uranian zonal winds with the latest entries being those proposed in Sromovsky et al. (2015). Karkoschka (2015) also provides a new view of the zonal winds, but in this case through reanalyzing the Voyager II observations. While all these profiles have in common features like a retrograde equatorial jet, the details of these profiles differ significantly. These differences can be further accentuated when considering the vorticity profiles derived from these zonal winds. As shown in LeBeau and Dowling (1998) and Hammel et al. (2009), atmospheric simulations using different zonal vorticity profiles suggest that the vorticity gradient can affect the dynamics of dark spot vortices in the atmosphere. Later work (Deng et al. 2009) has indicated that these dynamics may be further complicated by the presence of cloud companion features.To further investigate these interactions, some of the most recent zonal profiles are used in simulations of Uranus with the Explicit Planetary Isentropic Coordinate (EPIC) atmospheric model. By inducing vortices at different latitudes, the effects of different zonal wind profiles on these features can be investigated. A methane microphysics model is used to generate representative companion clouds. The subsequent vortex and companion cloud motions can then be compared to observations, providing another tool in the effort to understand possible changes in the zonal wind structure of Uranus.References:L.A. Sromovsky et al. Icarus 258:192-223, 2015E. Karkoschka. Icarus 250:294-307, 2015H.B. Hammel et al. Icarus 201:257-271, 2009R.P. LeBeau and T.E. Dowling. Icarus 132:239-265, 1998X. Deng et al. 1st AIAA Atmospheric and Space Environments

  12. Distortion of thermospheric air masses by horizontal neutral winds over Poker Flat Alaska measured using an all-sky scanning Doppler imager

    NASA Astrophysics Data System (ADS)

    Dhadly, M. S.; Conde, M.

    2016-01-01

    An air mass transported by a wind field will become distorted over time by any gradients present in the wind field. To study this effect in Earth's thermosphere, we examine the behavior of a simple parameter that we describe here as the "distortion gradient." It incorporates all of the wind field's departures from uniformity and is thus capable of representing all contributions to the distortion or mixing of air masses. The distortion gradient is defined such that it is always positive, so averaging over time and/or space does not suppress small-scale features. Conventional gradients, by contrast, are signed quantities that would often average to zero. To analyze the climatological behavior of this distortion gradient, we used three years (2010, 2011, and 2012) of thermospheric F region wind observations from a high-latitude ground-based all-sky wavelength scanning Doppler Fabry-Perot interferometer located at Poker Flat Alaska. Climatological averaging of the distortion gradient allowed us to investigate its diurnal and seasonal (annual) behaviors at our observing location. Distortion was observed to be higher before local magnetic midnight and to be seasonally dependent. While maximum distortion occurred before local magnetic midnight under all geomagnetic conditions, the peak distortion occurred earlier under moderate geomagnetic conditions as compared to the quiet geomagnetic conditions and even earlier still when geomagnetic conditions were active. Peak distortion was stronger and appeared earlier when interplanetary magnetic field (IMF) was southward compared to northward. By contrast, we could not resolve any time-shift effect due to the IMF component tangential to Earth's orbit.

  13. Sensitivities of eyewall replacement cycle to model physics, vortex structure, and background winds in numerical simulations of tropical cyclones

    NASA Astrophysics Data System (ADS)

    Zhu, Zhenduo; Zhu, Ping

    2015-01-01

    series of sensitivity experiments by the Weather Research and Forecasting (WRF) model is used to investigate the impact of model physics, vortex axisymmetric radial structure, and background wind on secondary eyewall formation (SEF) and eyewall replacement cycle (ERC) in three-dimensional full physics numerical simulations. It is found that the vertical turbulent mixing parameterization can substantially affect the concentric ring structure of tangential wind associated with SEF through a complicated interaction among eyewall and outer rainband heating, radial inflow in the boundary layer, surface layer processes, and shallow convection in the moat. Large snow terminal velocity can substantially change the vertical distribution of eyewall diabatic heating to result in a strong radial inflow in the boundary layer, and thus, favors the development of shallow convection in the moat allowing the outer rainband convection to move closer to the inner eyewall, which may leave little room both temporally and spatially for a full development of a secondary maximum of tangential wind. Small radius of maximum wind (RMW) of a vortex and small potential vorticity (PV) skirt outside the RMW tend to generate double-eyewall replacement and may lead to an ERC without a clean secondary concentric maximum of tangential wind. A sufficiently large background wind can smooth out an ERC that would otherwise occur without background wind for a vortex with a small or moderate PV skirt. However, background wind does not appear to have an impact on an ERC if the vortex has a sufficiently large PV skirt.

  14. Structures of HIV-1-Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

    PubMed Central

    Gorman, Jason; Soto, Cinque; Yang, Max M.; Davenport, Thaddeus M.; Guttman, Miklos; Bailer, Robert T.; Chambers, Michael; Chuang, Gwo-Yu; DeKosky, Brandon J.; Doria-Rose, Nicole A.; Druz, Aliaksandr; Ernandes, Michael J.; Georgiev, Ivelin S.; Jarosinski, Marissa C.; Joyce, M. Gordon; Lemmin, Thomas M.; Leung, Sherman; Louder, Mark K.; McDaniel, Jonathan R.; Narpala, Sandeep; Pancera, Marie; Stuckey, Jonathan; Wu, Xueling; Yang, Yongping; Zhang, Baoshan; Zhou, Tongqing; Mullikin, James C.; Baxa, Ulrich; Georgiou, George; McDermott, Adrian B.; Bonsignori, Mattia; Haynes, Barton F.; Moore, Penny L.; Morris, Lynn; Lee, Kelly K.; Shapiro, Lawrence; Mascola, John R.; Kwong, Peter D.

    2016-01-01

    Broadly neutralizing antibodies (bNAbs) against HIV-1-Env V1V2 arise in multiple donors. However, atomic-level interactions had only been determined with antibodies from a single donor, making commonalities in recognition uncertain. Here we report the co-crystal structure of V1V2 with antibody CH03 from a second donor and model Env interactions of antibody CAP256-VRC26 from a third. These V1V2-directed bNAbs utilized strand-strand interactions between a protruding antibody loop and a V1V2 strand, but differed in their N-glycan recognition. Ontogeny analysis indicated protruding loops to develop early, with glycan interactions maturing over time. Altogether, the multidonor information suggested V1V2-directed bNAbs to form an ‘extended class’, for which we engineered ontogeny-specific antigens: Env trimers with chimeric V1V2s that interacted with inferred ancestor and intermediate antibodies. The ontogeny-based design of vaccine antigens described here may provide a general means for eliciting antibodies of a desired class. PMID:26689967

  15. Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.

    PubMed

    Gorman, Jason; Soto, Cinque; Yang, Max M; Davenport, Thaddeus M; Guttman, Miklos; Bailer, Robert T; Chambers, Michael; Chuang, Gwo-Yu; DeKosky, Brandon J; Doria-Rose, Nicole A; Druz, Aliaksandr; Ernandes, Michael J; Georgiev, Ivelin S; Jarosinski, Marissa C; Joyce, M Gordon; Lemmin, Thomas M; Leung, Sherman; Louder, Mark K; McDaniel, Jonathan R; Narpala, Sandeep; Pancera, Marie; Stuckey, Jonathan; Wu, Xueling; Yang, Yongping; Zhang, Baoshan; Zhou, Tongqing; Mullikin, James C; Baxa, Ulrich; Georgiou, George; McDermott, Adrian B; Bonsignori, Mattia; Haynes, Barton F; Moore, Penny L; Morris, Lynn; Lee, Kelly K; Shapiro, Lawrence; Mascola, John R; Kwong, Peter D

    2016-01-01

    Broadly neutralizing antibodies (bNAbs) against HIV-1 Env V1V2 arise in multiple donors. However, atomic-level interactions had previously been determined only with antibodies from a single donor, thus making commonalities in recognition uncertain. Here we report the cocrystal structure of V1V2 with antibody CH03 from a second donor and model Env interactions of antibody CAP256-VRC26 from a third donor. These V1V2-directed bNAbs used strand-strand interactions between a protruding antibody loop and a V1V2 strand but differed in their N-glycan recognition. Ontogeny analysis indicated that protruding loops develop early, and glycan interactions mature over time. Altogether, the multidonor information suggested that V1V2-directed bNAbs form an 'extended class', for which we engineered ontogeny-specific antigens: Env trimers with chimeric V1V2s that interacted with inferred ancestor and intermediate antibodies. The ontogeny-based design of vaccine antigens described here may provide a general means for eliciting antibodies of a desired class. PMID:26689967

  16. Structural-dynamic-response characteristics of Darrieus vertical-axis wind turbines

    SciTech Connect

    Sullivan, W.N.

    1981-01-01

    Operational experience at Sandia National Laboratories (SNL) with Darrieus-type vertical axis wind turbines (VAWTs) has indicated that a variety of dynamic issues can affect structural performance of the system. The observation and analysis of structural dynamic responses in the VAWT have been divided among three major aspects of the system; namely rotor vibrations, torsional response of the drive train, and transverse vibrations of the cables. This division is not arbitrary, but is rather because the response of these subsystems can be accurately decoupled from each other in most circumstances. This paper will present only a brief summary of the efforts now underway at SNL in the area of structural dynamics. The emphasis will be on discussing the status of our analytical tools, the quantity and quality of existing experimental confirmation data, and the implications structural dynamic issues have on rotor design.

  17. Vibration Based Wind Turbine Tower Foundation Design Utilizing Soil-Foundation-Structure Interaction

    NASA Astrophysics Data System (ADS)

    Al Satari, P. E. Mohamed; Hussain, S. E. Saif

    2008-07-01

    Wind turbines have been used to generate electricity as an alternative energy source to conventional fossil fuels. This case study is for multiple wind towers located at different villages in Alaska where severe arctic weather conditions exist. The towers are supported by two different types of foundations; large mat or deep piles foundations. Initially, a Reinforced Concrete (RC) mat foundation was utilized to provide the system with vertical and lateral support. Where soil conditions required it, a pile foundation solution was devised utilizing a 30″ thick RC mat containing an embedded steel grillage of W18 beams supported by 20″-24″ grouted or un-grouted piles. The mixing and casting of concrete in-situ has become the major source of cost and difficulty of construction at these remote Alaska sites. An all-steel foundation was proposed for faster installation and lower cost, but was found to impact the natural frequencies of the structural system by significantly softening the foundation system. The tower-foundation support structure thus became near-resonant with the operational frequencies of the wind turbine leading to a likelihood of structural instability or even collapse. A detailed 3D Finite-Element model of the original tower-foundation-pile system with RC foundation was created using SAP2000. Soil springs were included in the model based on soil properties obtained from the geotechnical consultant. The natural frequency from the model was verified against the tower manufacturer analytical and the experimental values. Where piles were used, numerous iterations were carried out to eliminate the need for the RC and optimize the design. An optimized design was achieved with enough separation between the natural and operational frequencies to prevent damage to the structural system eliminating the need for any RC encasement to the steel foundation or grouting to the piles.

  18. Periodic Density Structures and the Origin of the Slow Solar Wind

    NASA Technical Reports Server (NTRS)

    Viall-Kepko, Nicholeen M.; Vourlidas, Angelos

    2015-01-01

    The source of the slow solar wind has challenged scientists for years. Periodic density structures (PDSs), observed regularly in the solar wind at 1 AU (Astronomical Unit), can be used to address this challenge. These structures have length scales of hundreds to several thousands of megameters and frequencies of tens to hundreds of minutes. Two lines of evidence indicate that PDSs are formed in the solar corona as part of the slow solar wind release and/or acceleration processes. The first is corresponding changes in compositional data in situ, and the second is PDSs observed in the inner Heliospheric Imaging data on board the Solar Terrestrial Relations Observatory (STEREO)/Sun Earth Connection Coronal and Heliospheric Investigation (SECCHI) suite. The periodic nature of these density structures is both a useful identifier as well as an important physical constraint on their origin. In this paper, we present the results of tracking periodic structures identified in the inner Heliospheric Imager in SECCHI back in time through the corresponding outer coronagraph (COR2) images. We demonstrate that the PDSs are formed around or below 2.5 solar radii-the inner edge of the COR2 field of view. We compute the occurrence rates of PDSs in 10 days of COR2 images both as a function of their periodicity and location in the solar corona, and we find that this set of PDSs occurs preferentially with a periodicity of approximately 90 minutes and occurs near streamers. Lastly, we show that their acceleration and expansion through COR2 is self-similar, thus their frequency is constant at distances beyond 2.5 solar radii.

  19. The Structural Changes of Tropical Cyclones Upon Interaction with Vertical Wind Shear

    NASA Technical Reports Server (NTRS)

    Ritchie, Elizabeth A.

    2003-01-01

    The Fourth Convection and Moisture Experiment (CAMEX-4) provided a unique opportunity to observe the distributions and document the roles of important atmospheric factors that impact the development of the core asymmetries and core structural changes of tropical cyclones embedded in vertical wind shear. The state-of-the-art instruments flown on the NASA DC-8 and ER-2, in addition to those on the NOAA aircraft, provided a unique set of observations that documented the core structure throughout the depth of the tropical cyclone. These data have been used to conduct a combined observational and modeling study using a state-of-the-art, high- resolution mesoscale model to examine the role of the environmental vertical wind shear in producing tropical cyclone core asymmetries, and the effects on the structure and intensity of tropical cyclones.The scientific objectives of this study were to obtain in situ measurements that would allow documentation of the physical mechanisms that influence the development of the asymmetric convection and its effect on the core structure of the tropical cyclone.

  20. Structural Considerations of a 20MW Multi-Rotor Wind Energy System

    NASA Astrophysics Data System (ADS)

    Jamieson, P.; Branney, M.

    2014-12-01

    The drive to upscale offshore wind turbines relates especially to possiblereductions in O&M and electrical interconnection costs per MW of installed capacity.Even with best current technologies, designs with rated capacity above about 3 MW are less cost effective exfactory per rated MW(turbine system costs) than smaller machines.Very large offshore wind turbines are thereforejustifiedprimarily by overall offshore project economics. Furthermore, continuing progress in materials and structures has been essential to avoid severe penalties in the power/mass ratio of large multi-MW machines.The multi-rotor concept employs many small rotors to maximise energy capture area withminimum systemvolume. Previous work has indicated that this can enablea very large reduction in the total weight and cost of rotors and drive trains compared to an equivalent large single rotor system.Thus the multi rotor concept may enable rated capacities of 20 MW or more at a single maintenancesite. Establishing the cost benefit of a multi rotor system requires examination of solutions for the support structure and yawing, ensuring aerodynamic losses from rotor interaction are not significant and that overall logistics, with much increased part count (more reliable components) and less consequence of single failuresare favourable. This paper addresses the viability of a support structure in respect of structural concept and likely weight as one necessary step in exploring the potential of the multi rotor concept.

  1. Influence of electron-neutral collisions on the Compton scattering cross section and the Salpeter structure factor in warm collisional plasmas

    NASA Astrophysics Data System (ADS)

    Song, Mi-Young; Yoon, Jung-Sik; Jung, Young-Dae

    2015-03-01

    The electron-neutral collision effects on the Compton scattering process are investigated in warm collisional plasmas. The Compton scattering cross section in warm collisional plasmas is obtained by the Salpeter structure factor with the fluctuation-dissipation theorem and the plasma dielectric function as a function of the electron-neutral collision frequency, Debye length, and wave number. It is shown that the influence of electron-neutral collision strongly suppresses the Compton scattering cross section in warm collisional plasmas. It is also found that the electron-neutral collision effect on the differential Compton scattering cross section is more significant in forward scattering directions. We show that the differential Compton scattering cross section has a maximum at the scattering angle φ = π / 2 . In addition, we find that the electron-neutral collision effect on the total Compton scattering cross section increases with increasing Debye length and wave number. The variation of the Compton scattering cross section due to the change of collision frequency and plasma parameters is also discussed.

  2. Influence of electron-neutral collisions on the Compton scattering cross section and the Salpeter structure factor in warm collisional plasmas

    SciTech Connect

    Song, Mi-Young; Yoon, Jung-Sik; Jung, Young-Dae

    2015-03-15

    The electron-neutral collision effects on the Compton scattering process are investigated in warm collisional plasmas. The Compton scattering cross section in warm collisional plasmas is obtained by the Salpeter structure factor with the fluctuation-dissipation theorem and the plasma dielectric function as a function of the electron-neutral collision frequency, Debye length, and wave number. It is shown that the influence of electron-neutral collision strongly suppresses the Compton scattering cross section in warm collisional plasmas. It is also found that the electron-neutral collision effect on the differential Compton scattering cross section is more significant in forward scattering directions. We show that the differential Compton scattering cross section has a maximum at the scattering angle φ=π/2. In addition, we find that the electron-neutral collision effect on the total Compton scattering cross section increases with increasing Debye length and wave number. The variation of the Compton scattering cross section due to the change of collision frequency and plasma parameters is also discussed.

  3. Solar Wind Structure at 1 AU: Comparison between Solar Minima 22/23 and 23/24

    NASA Astrophysics Data System (ADS)

    Jian, L.; Russell, C.; Luhmann, J. G.; Galvin, A. B.; Skoug, R. M.; Schroeder, P. C.

    2009-12-01

    The current solar minimum 23/24 has been unusually long and deep, compared with the solar minima in the space era. In order to see the consequence of the extremely quiet Sun on the solar wind, we compare the solar wind structure during the current solar minimum with the last solar minimum 22/23, which represents the case of a short and shallow solar minimum. Based on ACE, Wind, and STEREO in situ plasma and magnetic field observations, we identify and characterize stream interaction regions (SIRs), interplanetary CMEs (ICMEs), interplanetary shocks, sector boundaries, and other structures in the solar wind at 1 AU for 1995 - 1997 and 2007 - 2009. The properties of these structures, such as the occurrence rate, SIR and ICME scale and interaction strength, shock Mach number, correlation between sector boundary and SIR, will be studied. In addition to the statistical study, we will present some case studies of events from this deep solar minimum.

  4. Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases

    PubMed Central

    McGowan, Sheena; Oellig, Christine A.; Birru, Woldeamanuel A.; Caradoc-Davies, Tom T.; Stack, Colin M.; Lowther, Jonathan; Skinner-Adams, Tina; Mucha, Artur; Kafarski, Pawel; Grembecka, Jolanta; Trenholme, Katharine R.; Buckle, Ashley M.; Gardiner, Donald L.; Dalton, John P.; Whisstock, James C.

    2010-01-01

    Current therapeutics and prophylactics for malaria are under severe challenge as a result of the rapid emergence of drug-resistant parasites. The human malaria parasite Plasmodium falciparum expresses two neutral aminopeptidases, PfA-M1 and PfA-M17, which function in regulating the intracellular pool of amino acids required for growth and development inside the red blood cell. These enzymes are essential for parasite viability and are validated therapeutic targets. We previously reported the x-ray crystal structure of the monomeric PfA-M1 and proposed a mechanism for substrate entry and free amino acid release from the active site. Here, we present the x-ray crystal structure of the hexameric leucine aminopeptidase, PfA-M17, alone and in complex with two inhibitors with antimalarial activity. The six active sites of the PfA-M17 hexamer are arranged in a disc-like fashion so that they are orientated inwards to form a central catalytic cavity; flexible loops that sit at each of the six entrances to the catalytic cavern function to regulate substrate access. In stark contrast to PfA-M1, PfA-M17 has a narrow and hydrophobic primary specificity pocket which accounts for its highly restricted substrate specificity. We also explicate the essential roles for the metal-binding centers in these enzymes (two in PfA-M17 and one in PfA-M1) in both substrate and drug binding. Our detailed understanding of the PfA-M1 and PfA-M17 active sites now permits a rational approach in the development of a unique class of two-target and/or combination antimalarial therapy. PMID:20133789

  5. Multiple Interactions across the Surface of the gp120 Core Structure Determine the Global Neutralization Resistance Phenotype of Human Immunodeficiency Virus Type 1

    PubMed Central

    Bouma, Peter; Leavitt, Maria; Zhang, Peng Fei; Sidorov, Igor A.; Dimitrov, Dimiter S.; Quinnan, Gerald V.

    2003-01-01

    Resistance to neutralization is an important characteristic of primary isolates of human immunodeficiency virus type 1 (HIV-1) that relates to the potential for successful vaccination to prevent infection and use of immunotherapeutics for treatment of established infection. In order to further elucidate mechanisms responsible for neutralization resistance, we studied the molecular mechanisms that determine the resistance of the primary virus isolate of the strain HIV-1 MN to neutralization by soluble CD4 (sCD4). As is the case for the global neutralization resistance phenotype, sCD4 resistance depended upon sequences in the amino-terminal heptad repeat region of gp41 (HR1), as well as on multiple functional interactions within the envelope complex. The functional interactions that determined the resistance included interactions between the variable loop 1 and 2 (V1/V2) region and sequences in or near the CD4 binding site (CD4bs) and with the V3 loop. Additionally, the V3 loop region was found to interact functionally with sequences in the outer domain of gp120, distant from the CD4bs and coreceptor-binding site, as well as with a residue thought to be located centrally in the coreceptor-binding site. These and previous results provide the basis for a model by which functional signals that determine the neutralization resistance, high-infectivity phenotype depend upon interactions occurring across the surface of the gp120 core structure and involving variable loop structures and gp41. This model should be useful in efforts to define epitopes that may be important for primary virus neutralization. PMID:12829845

  6. A niche for neutrality.

    PubMed

    Adler, Peter B; Hillerislambers, Janneke; Levine, Jonathan M

    2007-02-01

    Ecologists now recognize that controversy over the relative importance of niches and neutrality cannot be resolved by analyzing species abundance patterns. Here, we use classical coexistence theory to reframe the debate in terms of stabilizing mechanisms (niches) and fitness equivalence (neutrality). The neutral model is a special case where stabilizing mechanisms are absent and species have equivalent fitness. Instead of asking whether niches or neutral processes structure communities, we advocate determining the degree to which observed diversity reflects strong stabilizing mechanisms overcoming large fitness differences or weak stabilization operating on species of similar fitness. To answer this question, we propose combining data on per capita growth rates with models to: (i) quantify the strength of stabilizing processes; (ii) quantify fitness inequality and compare it with stabilization; and (iii) manipulate frequency dependence in growth to test the consequences of stabilization and fitness equivalence for coexistence. PMID:17257097

  7. Composite Structural Analysis of Flat-Back Shaped Blade for Multi-MW Class Wind Turbine

    NASA Astrophysics Data System (ADS)

    Kim, Soo-Hyun; Bang, Hyung-Joon; Shin, Hyung-Ki; Jang, Moon-Seok

    2014-06-01

    This paper provides an overview of failure mode estimation based on 3D structural finite element (FE) analysis of the flat-back shaped wind turbine blade. Buckling stability, fiber failure (FF), and inter-fiber failure (IFF) analyses were performed to account for delamination or matrix failure of composite materials and to predict the realistic behavior of the entire blade region. Puck's fracture criteria were used for IFF evaluation. Blade design loads applicable to multi-megawatt (MW) wind turbine systems were calculated according to the Germanischer Lloyd (GL) guideline and the International Electrotechnical Commission (IEC) 61400-1 standard, under Class IIA wind conditions. After the post-processing of final load results, a number of principal load cases were selected and converted into applied forces at the each section along the blade's radius of the FE model. Nonlinear static analyses were performed for laminate failure, FF, and IFF check. For buckling stability, linear eigenvalue analysis was performed. As a result, we were able to estimate the failure mode and locate the major weak point.

  8. Structural health and prognostics management for the enhancement of offshore wind turbine operations and maintenance strategies

    DOE PAGESBeta

    Griffith, D. Todd; Yoder, Nathanael C.; Resor, Brian; White, Jonathan; Paquette, Joshua

    2013-09-19

    Offshore wind turbines are an attractive source for clean and renewable energy for reasons including their proximity to population centers and higher capacity factors. One obstacle to the more widespread installation of offshore wind turbines in the USA, however, is that recent projections of offshore operations and maintenance costs vary from two to five times the land-based costs. One way in which these costs could be reduced is through use of a structural health and prognostics management (SHPM) system as part of a condition-based maintenance paradigm with smart loads management. Our paper contributes to the development of such strategies bymore » developing an initial roadmap for SHPM, with application to the blades. One of the key elements of the approach is a multiscale simulation approach developed to identify how the underlying physics of the system are affected by the presence of damage and how these changes manifest themselves in the operational response of a full turbine. A case study of a trailing edge disbond is analysed to demonstrate the multiscale sensitivity of damage approach and to show the potential life extension and increased energy capture that can be achieved using simple changes in the overall turbine control and loads management strategy. Finally, the integration of health monitoring information, economic considerations such as repair costs versus state of health, and a smart loads management methodology provides an initial roadmap for reducing operations and maintenance costs for offshore wind farms while increasing turbine availability and overall profit.« less

  9. Structural health and prognostics management for the enhancement of offshore wind turbine operations and maintenance strategies

    SciTech Connect

    Griffith, D. Todd; Yoder, Nathanael C.; Resor, Brian; White, Jonathan; Paquette, Joshua

    2013-09-19

    Offshore wind turbines are an attractive source for clean and renewable energy for reasons including their proximity to population centers and higher capacity factors. One obstacle to the more widespread installation of offshore wind turbines in the USA, however, is that recent projections of offshore operations and maintenance costs vary from two to five times the land-based costs. One way in which these costs could be reduced is through use of a structural health and prognostics management (SHPM) system as part of a condition-based maintenance paradigm with smart loads management. Our paper contributes to the development of such strategies by developing an initial roadmap for SHPM, with application to the blades. One of the key elements of the approach is a multiscale simulation approach developed to identify how the underlying physics of the system are affected by the presence of damage and how these changes manifest themselves in the operational response of a full turbine. A case study of a trailing edge disbond is analysed to demonstrate the multiscale sensitivity of damage approach and to show the potential life extension and increased energy capture that can be achieved using simple changes in the overall turbine control and loads management strategy. Finally, the integration of health monitoring information, economic considerations such as repair costs versus state of health, and a smart loads management methodology provides an initial roadmap for reducing operations and maintenance costs for offshore wind farms while increasing turbine availability and overall profit.

  10. Structural health and prognostics management for offshore wind turbines : an initial roadmap.

    SciTech Connect

    Griffith, Daniel Todd; Resor, Brian Ray; White, Jonathan Randall; Paquette, Joshua A.; Yoder, Nathanael C.

    2012-12-01

    Operations and maintenance costs for offshore wind plants are expected to be significantly higher than the current costs for onshore plants. One way in which these costs may be able to be reduced is through the use of a structural health and prognostic management system as part of a condition based maintenance paradigm with smart load management. To facilitate the creation of such a system a multiscale modeling approach has been developed to identify how the underlying physics of the system are affected by the presence of damage and how these changes manifest themselves in the operational response of a full turbine. The developed methodology was used to investigate the effects of a candidate blade damage feature, a trailing edge disbond, on a 5-MW offshore wind turbine and the measurements that demonstrated the highest sensitivity to the damage were the local pitching moments around the disbond. The multiscale method demonstrated that these changes were caused by a local decrease in the blade's torsional stiffness due to the disbond, which also resulted in changes in the blade's local strain field. Full turbine simulations were also used to demonstrate that derating the turbine power by as little as 5% could extend the fatigue life of a blade by as much as a factor of 3. The integration of the health monitoring information, conceptual repair cost versus damage size information, and this load management methodology provides an initial roadmap for reducing operations and maintenance costs for offshore wind farms while increasing turbine availability and overall profit.

  11. Economics of online structural health monitoring of wind turbines: Cost benefit analysis

    NASA Astrophysics Data System (ADS)

    Van Dam, Jeremy; Bond, Leonard J.

    2015-03-01

    Operations and maintenance (O&M) costs have an average share over the lifetime of the turbine of approximately 20%-25% of the total levelized cost per kWh of electricity produced. Online structural health monitoring (OSHM) and condition-based maintenance (CBM) of wind turbine blades has the potential to reduce O&M costs and hence reduce the overall cost of wind energy. OSHM and CBM offer the potential to improve turbine blade life cycle management, limit the number of physical inspections, and reduce the potential for missed significant defects. An OSHM system would reduce the need for physical inspections, and have inspections occur only after problem detection takes place. In the economics of wind energy, failures and unplanned outages can cause significant downtime, particularly while waiting for the manufacturing and shipping of major parts. This paper will report a review and assessment of SHM technologies and a cost benefit analysis, which will examine whether the added costs associated with an OSHM system will give an adequate return on the investment. One method in which OSHM reduces costs is, in part, by converting corrective maintenance to preventative maintenance. This paper shows that under both best and worse conditions implementing an OSHM system is cost effective in more than 50% of the trials, which have been performed. Opportunities appear to exist to improve the economic justification for implementing OSHM.

  12. The Chromospheric Structure and Wind of the K-Supergiant Lambda Velorum

    NASA Astrophysics Data System (ADS)

    Carpenter, Kenneth G.; Ayres, T. R.; Brown, A.; Harper, G. M.; Wahlgren, G. M.

    2011-01-01

    Recently, the 1326-1466 Å region of the FUV spectrum of the K4 Ib-II supergiant Lambda Vel was observed with the Cosmic Origins Spectrograph (COS) on HST, as part of the Ayres and Redfield Cycle 17 SNAP program "SNAPing Coronal Iron.” This spectrum covers a region not previously recorded in Lambda Vel at high resolution and, in a mere 20 minutes of exposure, reveals an amazing treasure trove of information. It shows a wide variety of strong atomic and molecular emission lines formed in the chromosphere and multiple atomic absorption lines formed in the stellar wind, both superposed on a bright chromospheric continuum. Further evidence of the stellar wind is seen in the P Cygni profiles presented by the C II (UV 1) lines near 1335 Å. We combine this COS data with archival GHRS spectra of other selected FUV and NUV regions to better characterize the outer atmospheric structure of the star and its massive, outflowing wind.

  13. Structural optimization procedure of a composite wind turbine blade for reducing both material cost and blade weight

    NASA Astrophysics Data System (ADS)

    Hu, Weifei; Park, Dohyun; Choi, DongHoon

    2013-12-01

    A composite blade structure for a 2 MW horizontal axis wind turbine is optimally designed. Design requirements are simultaneously minimizing material cost and blade weight while satisfying the constraints on stress ratio, tip deflection, fatigue life and laminate layup requirements. The stress ratio and tip deflection under extreme gust loads and the fatigue life under a stochastic normal wind load are evaluated. A blade element wind load model is proposed to explain the wind pressure difference due to blade height change during rotor rotation. For fatigue life evaluation, the stress result of an implicit nonlinear dynamic analysis under a time-varying fluctuating wind is converted to the histograms of mean and amplitude of maximum stress ratio using the rainflow counting algorithm Miner's rule is employed to predict the fatigue life. After integrating and automating the whole analysis procedure an evolutionary algorithm is used to solve the discrete optimization problem.

  14. Statistical analysis of thermospheric density response to solar wind sector structure

    NASA Astrophysics Data System (ADS)

    Guo, Dongjie; Lei, Jiuhou; Dou, Xiankang

    2015-06-01

    The global averaged thermospheric mass density data during 1967-2007 are analyzed to investigate thermospheric response to solar wind sector structure. Well-defined solar wind sectors have polarities of interplanetary magnetic field (IMF) toward (+Bx, -By) or away (-Bx, +By) from the Sun for multiple days. In March, thermospheric mass densities increase from the away to toward polarities, with a maximum density perturbation of ~23% at 400 km with respect to the 11 day averages; they decline from the toward to away polarities, and the maximum reduction at 400 km can reach 12%, which is associated with a weakened heating effect of the geomagnetic activity. In September, thermospheric densities respond in an opposite way to the same sector structure as compared with the March results. In solstice seasons, thermospheric density variations in response to solar wind sector structure are typically smaller than 10% relative to the 11 day averages. Besides the seasonal dependence, relative density changes tend to become greater at higher altitude and lower solar activity. However, during solar minimum the density variations at 550 km are not substantially larger than those at 400 km due to the possible descending of the transition altitude between helium and atomic oxygen. Moreover, the corotating interaction region (CIR) has a high probability to occur around the sector boundary. Consequently, the CIR effects account for one third of the density enhancement at 400 km during ineffective-effective sectors, whereas the density reduction associated with effective-ineffective sectors can be impaired by about 50%, which is independent of altitude.

  15. Effect of coherent structures on energetic particle intensity in the solar wind

    NASA Astrophysics Data System (ADS)

    Tessein, Jeffrey A.

    Solar energetic particles in the solar wind are accelerated in both solar flares and shocks assocated with fast coronal mass ejections. They follow the interplanetary magnetic field and, upon reaching Earth, have implications for space weather. Space weather affects astronaut health and orbiting equipment through radiation hazard and electrical infrastructure on the ground with ground induced currents. Economic im- pacts include disruption of GPS and redirection of commercial polar flights due to a dangerous radiation environment over the poles. By studying how these particles interact with the magnetic fields we can better predict onset times and diffusion of these events. We find, using superposed epoch analysis and conditional statisitics from spacecraft observations that there is a strong association between energetic particles in the solar wind and magnetic discontinuities. This may be related to turbulent dissipa- tion mechanisms in which coherent structures in the solar wind seem to be preferred sites of heating, plasma instabilites and dissipation. In the case of energetic particles, magnetic reconnection and transport in flux tubes are likely to play a role. Though we focus on data away from large shocks, trapping can occur in the downstream region of shocks due to the preponderance of compressive turbulence in these areas. This thesis lays the ground work for the results described above with an intro- duction to solar wind and heliospheric physics in Chapter 1. Chapter 2 is an intro- duction to the acceleration mechanisms that give rise to observed energetic particle events. Chapter 3 describes various data analysis techniques and statistics that are bread and butter when analyzing spacecraft data for turbulence and energetic particle studies. Chapter 4 is a digression that covers preliminary studies that were done on the side; scale dependent kurtosis, ergodic studies and initial conditions for simulations. Chapter 5 contains that central published

  16. Broadening of the Interplanetary Helium Cone Structure Due to Elastic Collisions of LISM Helium Atoms with Solar Wind Ions

    NASA Technical Reports Server (NTRS)

    Fahr, H. J.; Nass, H. U.; Rucinski, D.

    1984-01-01

    Neutral interstellar particles penetrating into the heliosphere, besides being subject there to specific loss processes, suffer elastic collisions with KeV-solar wind ions. The momentum transfer to the neutrals connected with these collisions leads to a loss of angular momentum with respect to the Sun and to a fractional compensation of the effective solar gravity. The dynamical particle trajectories hence are changed into non-Keplerians leading to density and temperature distributions differing from those calculated in the past. This is found from a solution of the Boltzmann equation that linearizes the effect of this additional force. It is shown that the HeI-584A resonance glow of the heliospheric helium cone lead to substantially lower interstellar helium temperatures if re-interpreted on the basis of this revised theory. These temperatures now seem to be in accordance with the derived temperatures for interstellar hydrogen.

  17. Broadening of the interplanetary helium cone structure due to elastic collisions of LISM helium atoms with solar wind ions

    SciTech Connect

    Fahr, H.J.; Nass, H.U.; Rucinski, D.

    1984-11-01

    Neutral interstellar particles penetrating into the heliosphere, besides being subject there to specific loss processes, suffer elastic collisions with KeV-solar wind ions. The momentum transfer to the neutrals connected with these collisions leads to a loss of angular momentum with respect to the Sun and to a fractional compensation of the effective solar gravity. The dynamical particle trajectories hence are changed into non-Keplerians leading to density and temperature distributions differing from those calculated in the past. This is found from a solution of the Boltzmann equation that linearizes the effect of this additional force. It is shown that the HeI-584A resonance glow of the heliospheric helium cone lead to substantially lower interstellar helium temperatures if re-interpreted on the basis of this revised theory. These temperatures now seem to be in accordance with the derived temperatures for interstellar hydrogen.

  18. Structure of Turbulence in Katabatic Flows Below and Above the Wind-Speed Maximum

    NASA Astrophysics Data System (ADS)

    Grachev, Andrey A.; Leo, Laura S.; Sabatino, Silvana Di; Fernando, Harindra J. S.; Pardyjak, Eric R.; Fairall, Christopher W.

    2016-06-01

    Measurements of small-scale turbulence made in the atmospheric boundary layer over complex terrain during the Mountain Terrain Atmospheric Modeling and Observations (MATERHORN) Program are used to describe the structure of turbulence in katabatic flows. Turbulent and mean meteorological data were continuously measured on four towers deployed along the east lower slope (2-4°) of Granite Mountain near Salt Lake City in Utah, USA. The multi-level (up to seven) observations made during a 30-day long MATERHORN field campaign in September-October 2012 allowed the study of temporal and spatial structure of katabatic flows in detail, and herein we report turbulence statistics (e.g., fluxes, variances, spectra, and cospectra) and their variations in katabatic flow. Observed vertical profiles show steep gradients near the surface, but in the layer above the slope jet the vertical variability is smaller. It is found that the vertical (normal to the slope) momentum flux and horizontal (along-slope) heat flux in a slope-following coordinate system change their sign below and above the wind maximum of a katabatic flow. The momentum flux is directed downward (upward) whereas the along-slope heat flux is downslope (upslope) below (above) the wind maximum. This suggests that the position of the jet-speed maximum can be obtained by linear interpolation between positive and negative values of the momentum flux (or the along-slope heat flux) to derive the height where the flux becomes zero. It is shown that the standard deviations of all wind-speed components (and therefore of the turbulent kinetic energy) and the dissipation rate of turbulent kinetic energy have a local minimum, whereas the standard deviation of air temperature has an absolute maximum at the height of wind-speed maximum. We report several cases when the destructive effect of vertical heat flux is completely cancelled by the generation of turbulence due to the along-slope heat flux. Turbulence above the wind

  19. Structural dynamic testing of composite propfan blades for a cruise missile wind tunnel model

    NASA Technical Reports Server (NTRS)

    Elgin, Stephen D.; Sutliff, Thomas J.

    1993-01-01

    The Naval Weapons Center at China Lake, California is currently evaluating a counter rotating propfan system as a means of propulsion for the next generation of cruise missiles. The details and results of a structural dynamic test program are presented for scale model graphite-epoxy composite propfan blades. These blades are intended for use on a cruise missile wind tunnel model. Both dynamic characteristics and strain operating limits of the blades are presented. Complications associated with high strain level fatigue testing methods are also discussed.

  20. Development of Self-Powered Wireless Structural Health Monitoring (SHM) for Wind Turbine Blades

    NASA Astrophysics Data System (ADS)

    Lim, Dong-Won

    Wind turbine blade failure can lead to unexpected power interruptions. Monitoring wind turbine blades is important to ensure seamless electricity delivery from power generation to consumers. Structural health monitoring (SHM) enables early recognition of structural problems so that the safety and reliability of operation can be enhanced. This dissertation focuses on the development of a wireless SHM system for wind turbine blades. The sensor is comprised of a piezoelectric energy harvester (EH) and a telemetry unit. The sensor node is mounted on the blade surface. As the blade rotates, the blade flexes, and the energy harvester captures the strain energy on the blade surface. Once sufficient electricity is captured, a pulse is sent from the sensing node to a gateway. Then, a central monitoring algorithm processes a series of pulses received from all three blades. This wireless SHM, which uses commercially available components, can be retrofitted to existing turbines. The harvested energy for sensing can be estimated in terms of two factors: the available strain energy and conversion efficiency. The available strain energy was evaluated using the FAST (Fatigue, Aerodynamics, Structures, and Turbulence) simulator. The conversion efficiency was studied analytically and experimentally. An experimental set-up was designed to mimic the expected strain frequency and amplitude for rotor blades. From a series of experiments, the efficiency of a piezoelectric EH at a typical rotor speed (0.2 Hz) was approximately 0.5%. The power requirement for sending one measurement (280 muJ) can be achieved in 10 minutes. Designing a detection algorithm is challenging due to this low sampling rate. A new sensing approach-the timing of pulses from the transmitter-was introduced. This pulse timing, which is tied to the charging time, is indicative of the structural health. The SHM system exploits the inherent triple redundancy of the three blades. The timing data of the three blades are