Science.gov

Sample records for off-road vehicle trails

  1. Analyzing the impacts of off-road vehicle (ORV) trails on watershed processes in Wrangell-St. Elias National Park and Preserve, Alaska.

    PubMed

    Arp, Christopher D; Simmons, Trey

    2012-03-01

    Trails created by off-road vehicles (ORV) in boreal lowlands are known to cause local impacts, such as denuded vegetation, soil erosion, and permafrost thaw, but impacts on stream and watershed processes are less certain. In Wrangell-St. Elias National Park and Preserve (WRST), Alaska, ORV trails have caused local resource damage in intermountain lowlands with permafrost soils and abundant wetlands and there is a need to know whether these impacts are more extensive. Comparison of aerial photography from 1957, 1981, and 2004 coupled with ground surveys in 2009 reveal an increase in trail length and number and show an upslope expansion of a trail system around points of stream channel initiation. We hypothesized that these impacts could also cause premature initiation and headward expansion of channels because of lowered soil resistance and greater runoff accumulation as trails migrate upslope. Soil monitoring showed earlier and deeper thaw of the active layer in and adjacent to trails compared to reference sites. Several rainfall-runoff events during the summer of 2009 showed increased and sustained flow accumulation below trail crossings and channel shear forces sufficient to cause headward erosion of silt and peat soils. These observations of trail evolution relative to stream and wetland crossings together with process studies suggest that ORV trails are altering watershed processes. These changes in watershed processes appear to result in increasing drainage density and may also alter downstream flow regimes, water quality, and aquatic habitat. Addressing local land-use disturbances in boreal and arctic parklands with permafrost soils, such as WRST, where responses to climate change may be causing concurrent shifts in watershed processes, represents an important challenge facing resource managers. PMID:22327506

  2. 36 CFR 13.702 - Off-Road Vehicles.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...Regulations-Bering Land Bridge National Preserve § 13.702 Off-Road Vehicles. The use of off-road vehicles for purposes of reindeer grazing may be permitted in accordance with a permit issued by the...

  3. 36 CFR 13.702 - Off-Road Vehicles.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...Regulations-Bering Land Bridge National Preserve § 13.702 Off-Road Vehicles. The use of off-road vehicles for purposes of reindeer grazing may be permitted in accordance with a permit issued by the...

  4. 36 CFR 13.702 - Off-Road Vehicles.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...Regulations-Bering Land Bridge National Preserve § 13.702 Off-Road Vehicles. The use of off-road vehicles for purposes of reindeer grazing may be permitted in accordance with a permit issued by the...

  5. 36 CFR 13.702 - Off-Road Vehicles.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...Regulations-Bering Land Bridge National Preserve § 13.702 Off-Road Vehicles. The use of off-road vehicles for purposes of reindeer grazing may be permitted in accordance with a permit issued by the...

  6. 36 CFR 13.702 - Off-Road Vehicles.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Regulations-Bering Land Bridge National Preserve § 13.702 Off-Road Vehicles. The use of off-road vehicles for purposes of reindeer grazing may be permitted in accordance with a permit issued by the...

  7. RAVON --The Robust Autonomous Vehicle for Off-road Navigation

    E-print Network

    Berns, Karsten

    RAVON -- The Robust Autonomous Vehicle for Off-road Navigation C. Armbrust, T. Braun, T. Föhst, M, the Robust Autonomous Vehicle for Off-road Navigation (see figure 1). A sophisticated hazard detection-road Navigation 2 Figure 1: The autonomous off-road robot RAVON 1.1 The need for autonomy During the recent years

  8. 36 CFR 13.903 - Subsistence use of off-road vehicles.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...motor vehicle off road for subsistence purposes outside any trail or area designated by this section is prohibited. A map and GPS coordinates of designated trails and areas are available on the park website and at the park visitor center. (a)...

  9. 36 CFR 13.903 - Subsistence use of off-road vehicles.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...motor vehicle off road for subsistence purposes outside any trail or area designated by this section is prohibited. A map and GPS coordinates of designated trails and areas are available on the park website and at the park visitor center. (a)...

  10. Evaluating Environmental Impacts of Off-Road Vehicles.

    ERIC Educational Resources Information Center

    Kay, Jeanne; And Others

    1981-01-01

    Discusses a study undertaken to determine the ecological effects of off-road vehicles, such as four-wheel drive trucks and dirt bikes in the Big Cottonwood Canyon area near Salt Lake City. Applications of the study to other investigations of off-road vehicles are discussed. (DB)

  11. 36 CFR 13.903 - Subsistence use of off-road vehicles.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...determines that the following conditions are met: (1) Access across adjacent non-NPS lands has been secured; (2) An NPS-approved trail has been constructed on NPS lands; and (3) Off-road vehicle use continues to be necessary for...

  12. Spine Trauma Associated with Off-Road Vehicles.

    ERIC Educational Resources Information Center

    Reid, David C.; And Others

    1988-01-01

    A seven-year review of 1,447 cases of spine trauma showed that 53 cases were associated with the use of off-road vehicles, such as all-terrain vehicles, snowmobiles, and motorized dirt bikes. The development of safe riding areas, legislation governing safe operation, and public safety education are advised to curb this trend. (Author/JL)

  13. 76 FR 64102 - Big Cypress National Preserve Off-Road Vehicle Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-17

    ...NPS-SERO-WAPC-0911-8447; 2031-A048-409] Big Cypress National Preserve Off-Road Vehicle...Interior is giving notice of renewal of the Big Cypress National Preserve Off-Road Vehicle...to management of off-road vehicles at Big Cypress National Preserve. FOR...

  14. 76 FR 64102 - Big Cypress National Preserve Off-Road Vehicle Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-17

    ... National Park Service Big Cypress National Preserve Off-Road Vehicle Advisory Committee AGENCY: National... notice of renewal of the Big Cypress National Preserve Off-Road Vehicle Advisory Committee to offer recommendations, alternatives and possible solutions to management of off-road vehicles at Big Cypress...

  15. Off-road perception testbed vehicle design and evaluation

    NASA Astrophysics Data System (ADS)

    Spofford, John R.; Herron, Jennifer B.; Anhalt, David J.; Morgenthaler, Matthew K.; DeHerrera, Clinton

    2003-09-01

    Off-road robotics efforts such as DARPA"s PerceptOR program have motivated the development of testbed vehicles capable of sustained operation in a variety of terrain and environments. This paper describes the retrofitting of a minimally-modified ATV chassis into such a testbed which has been used by multiple programs for autonomous mobility development and sensor characterization. Modular mechanical interfaces for sensors and equipment enclosures enabled integration of multiple payload configurations. The electric power subsystem was capable of short-term operation on batteries with refueled generation for continuous operation. Processing subsystems were mounted in sealed, shock-dampened enclosures with heat exchangers for internal cooling to protect against external dust and moisture. The computational architecture was divided into a real-time vehicle control layer and an expandable high level processing and perception layer. The navigation subsystem integrated real time kinematic GPS with a three-axis IMU for accurate vehicle localization and sensor registration. The vehicle software system was based on the MarsScape architecture developed under DARPA"s MARS program. Vehicle mobility software capabilities included route planning, waypoint navigation, teleoperation, and obstacle detection and avoidance. The paper describes the vehicle design in detail and summarizes its performance during field testing.

  16. 36 CFR 13.1109 - Off-road vehicle use in Glacier Bay National Preserve.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...false Off-road vehicle use in Glacier Bay National Preserve. 13.1109 Section...IN ALASKA Special Regulations-Glacier Bay National Park and Preserve Administrative...1109 Off-road vehicle use in Glacier Bay National Preserve. The use of...

  17. 36 CFR 13.1109 - Off-road vehicle use in Glacier Bay National Preserve.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 false Off-road vehicle use in Glacier Bay National Preserve. 13.1109 ...UNITS IN ALASKA Special Regulations-Glacier Bay National Park and Preserve Administrative...13.1109 Off-road vehicle use in Glacier Bay National Preserve. The use...

  18. 36 CFR 13.1109 - Off-road vehicle use in Glacier Bay National Preserve.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 false Off-road vehicle use in Glacier Bay National Preserve. 13.1109 ...UNITS IN ALASKA Special Regulations-Glacier Bay National Park and Preserve Administrative...13.1109 Off-road vehicle use in Glacier Bay National Preserve. The use...

  19. 36 CFR 13.1109 - Off-road vehicle use in Glacier Bay National Preserve.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 false Off-road vehicle use in Glacier Bay National Preserve. 13.1109 ...UNITS IN ALASKA Special Regulations-Glacier Bay National Park and Preserve Administrative...13.1109 Off-road vehicle use in Glacier Bay National Preserve. The use...

  20. 36 CFR 13.1109 - Off-road vehicle use in Glacier Bay National Preserve.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 false Off-road vehicle use in Glacier Bay National Preserve. 13.1109 ...UNITS IN ALASKA Special Regulations-Glacier Bay National Park and Preserve Administrative...13.1109 Off-road vehicle use in Glacier Bay National Preserve. The use...

  1. Injuries related to off-road vehicles in Canada.

    PubMed

    Vanlaar, Ward; McAteer, Heather; Brown, Steve; Crain, Jennifer; McFaull, Steven; Hing, Marisela Mainegra

    2015-02-01

    Off-road vehicles (ORVs; this includes snowmobiles, all-terrain vehicles or ATVs and dirt bikes) were once used primarily for work and travel. Such use remains common in Canada, although their recreational use has also gained popularity in recent years. An epidemiological injury profile of ORV users is important for better understanding injuries and their risk factors to help inform injury prevention initiatives. The Traffic Injury Research Foundation (TIRF) partnered with the Public Health Agency of Canada (PHAC) to analyze the epidemiology of ORV-related injuries. The primary aim was to assess crashes and injuries in Canada, including the extent of alcohol involvement. Secondly, the burden of injury among children and teen ORV drivers in Canada, as well as passengers, was investigated. Descriptive and inferential epidemiological statistics were generated using the following data sources: first, TIRF's National Fatality Database, which is a comprehensive, pan-Canadian, set of core data on all fatal motor vehicle crashes; second, TIRF's Serious Injury Database, which contains information on persons seriously injured in crashes; and, third, PHAC's Canadian Hospitals Injury Reporting and Prevention Program (CHIRPP), a surveillance system currently operating in the emergency departments of some pediatric and general hospitals across Canada. Exposure data have been used in the analyzes where available. Between 1990 and 2010, fatality rates increased among ATV and dirt bike operators. The fatality rate among snowmobilers declined during this period. Of particular concern, among fatally injured female ATV users, children aged 0-15 years comprised the highest proportion of any age group at 33.8%. Regarding alcohol use, among fatally injured snowmobile and ATV/dirt bike operators tested for alcohol, 66% and 55% tested positive, respectively. Alcohol involvement in adult ORV crashes remains an important factor. In light of the growing popularity of ORVs, prevention and mitigation measures are required to address this issue. PMID:25528439

  2. 78 FR 61380 - Notice of Renewal of Big Cypress National Preserve Off-Road Vehicle Advisory Committee Charter

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-03

    ...PPMPSPD1Z.YM0000] Notice of Renewal of Big Cypress National Preserve Off-Road Vehicle...Interior. ACTION: Notice of renewal of the big cypress national preserve off-road vehicle...Interior is giving notice of renewal of the Big Cypress National Preserve Off-Road...

  3. 78 FR 5494 - Off-Road Vehicle Management Plan, Draft Environmental Impact Statement, Lake Meredith National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ...Pursuant to Sec. 102(2)(C) the National Environmental Policy Act of 1969, 42 U.S.C. 4332(2)(C), the National Park Service (NPS) is releasing a Draft Environmental Impact Statement (DEIS) for the Off- Road Vehicle Management Plan (Plan), Lake Meredith National Recreation Area (LAMR), Texas. The Plan/DEIS evaluates the impacts of four alternatives that address off-road vehicle (ORV) management......

  4. Monitoring and assessing global impacts of roads and off-road vehicle traffic

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Rapid increases in the number of vehicles, urban sprawl, exurban development and infrastructure development for energy and water have led to dramatic increases in both the size and extent of the global road network. Anecdotal evidence suggests that off-road vehicle traffic has also increased in many...

  5. Fugitive particulate air emissions from off-road vehicle maneuvers at military training lands

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Military training lands used for off-road vehicle maneuvers may be subject to severe soil loss and air quality degradation as a result of severe wind erosion. The objective of this study was to measure suspended particulate matter resulting from various different vehicle training scenarios. Soil s...

  6. 77 FR 6581 - Meetings of the Big Cypress National Preserve Off-Road Vehicle Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-08

    ...NPS-SER-BICY-1220-9207; 5120-SZM] Meetings of the Big Cypress National Preserve Off-Road Vehicle...notice is hereby given of the meetings of the Big Cypress National Preserve ORV Advisory Committee...ADDRESSES: All meetings will be held at the Big Cypress Swamp Welcome Center, 33000...

  7. Path planning for off-road vehicles with a simulator-in-the-loop

    E-print Network

    Hellström, Thomas

    system is to extend a standard path-tracking algorithm with a simulator that, in real-time, triesPath planning for off-road vehicles with a simulator-in-the-loop Thomas Hellström, thomash University SE-901 87 Umeå, Sweden May 6, 2008 Abstract This paper describes the development of a real-time

  8. Future Emissions Impact On Off-Road Vehicles

    SciTech Connect

    Kirby Baumgard; Steve Ephraim

    2001-04-18

    Summaries of paper: Emission requirements dictate vehicle update cycles; Packaging, performance and cost impacted; Styling updates can be integrated; Opportunity to integrate features and performance; Non-uniform regulations challenge resources; and Customers won't expect to pay more or receive less.

  9. 77 FR 77090 - 2013 Meetings of the Big Cypress National Preserve Off-Road Vehicle (ORV) Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-31

    ...PPMPSPD1Z.YM0000] 2013 Meetings of the Big Cypress National Preserve Off-Road Vehicle...notice is hereby given of the meetings of the Big Cypress National Preserve ORV Advisory Committee...ADDRESSES: All meetings will be held at the Big Cypress Swamp Welcome Center, 33000...

  10. 76 FR 35468 - Cancellation of June 23, 2011, Meeting of the Big Cypress National Preserve Off-Road Vehicle (ORV...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-17

    ...Cancellation of June 23, 2011, Meeting of the Big Cypress National Preserve Off-Road Vehicle...that the June 23, 2011, meeting of the Big Cypress National Preserve ORV Advisory Committee...CONTACT: Pedro Ramos, Superintendent, Big Cypress National Preserve, 33100...

  11. 75 FR 1809 - 2010 Meetings of the Big Cypress National Preserve Off-Road Vehicle (ORV) Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-13

    ...National Park Service 2010 Meetings of the Big Cypress National Preserve Off-Road Vehicle...notice is hereby given of the meetings of the Big Cypress National Preserve ORV Advisory Committee...ADDRESSES: All meetings will be held at the Big Cypress Swamp Welcome Center, 33000...

  12. 76 FR 3653 - 2011 Meetings of the Big Cypress National Preserve Off-Road Vehicle (ORV) Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-20

    ...NPS-SER-BICY-1217-6429; 5120-SZM] 2011 Meetings of the Big Cypress National Preserve Off-Road Vehicle...notice is hereby given of the meetings of the Big Cypress National Preserve ORV Advisory Committee...ADDRESSES: All meetings will be held at the Big Cypress Swamp Welcome Center, 33000...

  13. 76 FR 52690 - Final Environmental Impact Statement on Nabesna Off-Road Vehicle Management Plan, Wrangell-St...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-23

    ... National Park Service Final Environmental Impact Statement on Nabesna Off-Road Vehicle Management Plan...) the National Park Service (NPS) announces the availability of a Final Environmental Impact Statement... only when the ground is frozen. A Draft Environmental Impact Statement (DEIS) was published in...

  14. A suite of tools for monitoring and assessing impacts of road networks and off-road vehicle activity on rangelands

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Despite increasing amounts of transportation related activities on rangelands globally, few tools exist for assessing and monitoring impacts of roads, road networks and off-road vehicle traffic. This is in part due to an historical emphasis on grazing issues in rangelands and the complexity of monit...

  15. 75 FR 71730 - General Management Plan/Wilderness Study/Off-Road Vehicle Management Plan, Final Environmental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... Management Plan/Wilderness Study/Off-Road Vehicle Management Plan (FEIS/GMP/WS/ORV Plan), Big Cypress... Decision- making), the NPS announces the availability of a Final Environmental Impact Statement for the GMP/WS/ORV Plan for the Big Cypress National Preserve Addition, Florida. The 1991 GMP for the...

  16. Helmet use among Alaskan children involved in off-road motorized vehicle crashes

    PubMed Central

    Snyder, Christopher W.; Muensterer, Oliver J.; Sacco, Frank; Safford, Shawn D.

    2014-01-01

    Background Off-road motorized vehicle crashes are a common source of trauma among Alaska children. Injury morbidity is worse in Alaska Native children than non-Native children, but the reasons are unclear. Objective To evaluate the differences in helmet use between the Native and the non-Native children, and to assess the impact of helmet use on injury patterns and outcomes. Design This retrospective cohort study identified patients aged 17 or younger admitted after all-terrain vehicle, snowmobile or motorbike injury between 2001 and 2011 from the Alaska Trauma Registry. Helmeted and non-helmeted patients were compared with respect to demographics, central nervous system (CNS) injury and the overall risk of death or permanent disability. Logistic regression was used to evaluate predictors of helmet use and the effects of ethnicity and helmet use on outcomes. Results Of the 921 injured children, 51% were Alaska Native and 49% were non-Native. Helmet use was lower among Native versus non-Native patients on unadjusted comparison (24% vs. 71%) and multivariable logistic regression (OR 0.17, 95% CI 0.11–0.27, p<0.0001). Prevalence of CNS injury was higher among Native children (39.7% vs. 30.4%, p=0.016). However, on logistic regression with adjustment for helmet use, Native ethnicity was not a significant predictor of CNS injury (OR 1.07, 95% CI 0.68–1.68, p=0.78), whereas helmet use was strongly protective against CNS injury (OR 0.28, 95% CI 0.18–0.44, p<0.0001) as well as death or permanent disability (OR 0.26, 95% CI 0.10–0.67, p=0.006). Conclusions Helmet use is lower among Alaska Native children involved in off-road motorized vehicle crashes. These ethnic disparities in helmet use contribute to higher rates of CNS injury among Native children. Helmet use significantly improves overall outcome. Helmet promotion efforts should be expanded, especially in Native communities. PMID:25317382

  17. 36 CFR 13.903 - Subsistence use of off-road vehicles.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...coordinates of designated trails and areas are available on the park website and at the park visitor center. (a) Authorized residents...release, posting at local post offices, posting on the park website, posting signs at designated trails or areas if...

  18. 36 CFR 13.903 - Subsistence use of off-road vehicles.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...coordinates of designated trails and areas are available on the park website and at the park visitor center. (a) Authorized residents...release, posting at local post offices, posting on the park website, posting signs at designated trails or areas if...

  19. 36 CFR 13.903 - Subsistence use of off-road vehicles.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... designated trails and areas are available on the park website and at the park visitor center. (a) Authorized... issuing a press release, posting at local post offices, posting on the park website, posting signs...

  20. 36 CFR 13.903 - Subsistence use of off-road vehicles.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... designated trails and areas are available on the park website and at the park visitor center. (a) Authorized... issuing a press release, posting at local post offices, posting on the park website, posting signs...

  1. 36 CFR 13.903 - Subsistence use of off-road vehicles.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... designated trails and areas are available on the park website and at the park visitor center. (a) Authorized... issuing a press release, posting at local post offices, posting on the park website, posting signs...

  2. 36 CFR 13.903 - Subsistence use of off-road vehicles.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... designated trails and areas are available on the park website and at the park visitor center. (a) Authorized... issuing a press release, posting at local post offices, posting on the park website, posting signs...

  3. Vegetation versus man-made object detection from imagery for unmanned vehicles in off-road environments

    NASA Astrophysics Data System (ADS)

    Harguess, Josh; Larson, Jacoby

    2013-05-01

    There have been several major advances in autonomous navigation for unmanned ground vehicles in controlled urban environments in recent years. However, off-road environments still pose several perception and classification challenges. This paper addresses two of these challenges: detection and classification of vegetation vs. man-made objects. In order for a vehicle or remote operator to traverse cross-country terrain, automated decisions must be made about obstacles in the vehicle's path. The most common obstacle is vegetation, but some vegetation may be traversable, depending on the size of the vehicle and the type of vegetation. However, man­ made objects should generally be detected and avoided in navigation. We present recent research towards the goal of vegetation and man-made object detection in the visible spectrum. First, we look at a state-of-the-art approach to image segmentation and image saliency using natural scene statistics. Then we apply recent work in multi-class image labeling to several images taken from a small unmanned ground vehicle (UGV). This work will attempt to highlight the recent advances and challenges that lie ahead in the ultimate goal of vegetation and man-made object detection and classification in the visual spectrum from UGV.

  4. Fuel Used for Off-Road Recreation: A Reassessment of the Fuel Use Model

    SciTech Connect

    Davis, S.C.; Truett, L.F.; Hu, P.S.

    1999-07-01

    The Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA) established a National Recreational Trails Funding Program and the National Recreational Trails Trust Fund. ISTEA required that certain tax revenue generated from the sales of motor fuel used for off-road recreation be transferred from the Highway Trust Funds to the Trails Trust Fund for recreational trail and facility improvements. In order to apportion the Trails Trust Fund to individual States equitably, the Federal Highway Administration (FHWA) asked the Oak Ridge National Laboratory (ORNL) in 1993 to estimate the amount of motor fuel used for off-road recreation in the State level by different vehicle types. A modification of the methodology developed by ORNL has been used to apportion funds to the States since that time.

  5. Impacts of off-road vehicles on nitrogen cycles in biological soil crusts: Resistance in different U.S. deserts

    USGS Publications Warehouse

    Belnap, J.

    2002-01-01

    Biological soil crusts are an important component of desert ecosystems, as they influence soil stability and fertility. This study examined and compared the short-term vehicular impacts on lichen cover and nitrogenase activity (NA) of biological soil crusts. Experimental disturbance was applied to different types of soil in regions throughout the western U.S. (Great Basin, Colorado Plateau, Sonoran, Chihuahuan, and Mojave deserts). Results show that pre-disturbance cover of soil lichens is significantly correlated with the silt content of soils, and negatively correlated with sand and clay. While disturbance appeared to reduce NA at all sites, differences were statistically significant at only 12 of the 26 sites. Cool desert sites showed a greater decline than hot desert sites, which may indicate non-heterocystic cyanobacterial species are more susceptible to disturbance than non-heterocystic species. Sandy soils showed greater reduction of NA as sand content increased, while fine-textured soils showed a greater decline as sand content increased. At all sites, higher NA before the disturbance resulted in less impact to NA post-disturbance. These results may be useful in predicting the impacts of off-road vehicles in different regions and different soils. ?? 2002 Published by Elsevier Science Ltd.

  6. Off-Road Vehicle Impact on Sediment Displacement and Disruption at Assateague Island National Seashore, Maryland 

    E-print Network

    Labude, Brian

    2012-08-15

    -scale impact. This study quantifies the sediment disturbance made by tire tracks, as well as the tire track form, width, depth, and evolution with relation to the number of vehicle passes and location on the beach at Assateague Island National Seashore (ASIS...

  7. Real-time adaptive off-road vehicle navigation and terrain classification

    NASA Astrophysics Data System (ADS)

    Muller, Urs A.; Jackel, Lawrence D.; LeCun, Yann; Flepp, Beat

    2013-05-01

    We are developing a complete, self-contained autonomous navigation system for mobile robots that learns quickly, uses commodity components, and has the added benefit of emitting no radiation signature. It builds on the au­tonomous navigation technology developed by Net-Scale and New York University during the Defense Advanced Research Projects Agency (DARPA) Learning Applied to Ground Robots (LAGR) program and takes advantage of recent scientific advancements achieved during the DARPA Deep Learning program. In this paper we will present our approach and algorithms, show results from our vision system, discuss lessons learned from the past, and present our plans for further advancing vehicle autonomy.

  8. 76 FR 52690 - Final Environmental Impact Statement on Nabesna Off-Road Vehicle Management Plan, Wrangell-St...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-23

    ...Copper Lake, Boomerang). All trails (except Suslota) would be improved to at least a maintainable condition through trail hardening, tread improvement, or constructed re-routes. Subsistence ORV use would continue subject to monitoring and...

  9. Autonomous Off-Road Driving in the DARPA Grand Challenge

    E-print Network

    Soatto, Stefano

    Autonomous Off-Road Driving in the DARPA Grand Challenge Eagle Jones, Brian Fulkerson, and Emilio-speed autonomous driving in the structured highway environment for years. However, it is clear learned from two years of autonomous vehicle develop- ment. Autonomous navigation in the off road

  10. Impact of off-road vehicles (ORVs) on ghost crabs of sandy beaches with traffic restrictions: a case study of Sodwana Bay, South Africa.

    PubMed

    Lucrezi, Serena; Saayman, Melville; van der Merwe, Peet

    2014-03-01

    Off-road vehicles (ORVs) are popular in coastal recreation, although they have negative impacts on sandy shores. In South Africa, ORVs are banned from most coastal areas, while some areas are designated for restricted ORV use, providing an opportunity to assess whether ORV traffic restrictions translate into biological returns. In Sodwana Bay, the impact of ORVs on ghost crab populations was investigated. During Easter 2012, ghost crab burrows were counted on beach sections open and closed to traffic. Burrow density in the Impact section was less than a third that of the Reference section, and by the end of the study burrow size in the Impact section was half that of the Reference section. ORV traffic caused a shift in burrow distribution to the Lower beach. However, differences in burrow densities between sections were 14 times smaller than differences obtained at a time when ORV use in Sodwana Bay was not controlled. While confirming the well-established detrimental effects of ORV use on sandy beach ecosystems, results demonstrated that traffic restrictions on beaches measurably minimize impacts to the fauna, thus translating into clear-cut biological returns. PMID:24370998

  11. Assessment of propeller and off-road vehicle scarring in seagrass beds and wind-tidal flats of the southwestern Gulf of Mexico

    USGS Publications Warehouse

    Martin, S.R.; Onuf, C.P.; Dunton, K.H.

    2008-01-01

    We used aerial photography and GIS to establish a quantitative baseline of propeller and off-road vehicle (ORV) scarring in seagrass and wind-tidal flats of the upper Laguna Madre in the Padre Island National Seashore (Texas, USA). We also examined scar recovery through comparison of recent (2002, 2005) and historical (1967) aerial photographs of the study area. Scarring intensity was calculated using two different methods. In the first, polygons were visually drawn around groups of scars on digital images. Scarring intensity was estimated as light (20%), based on the total coverage of scars within each polygon (taking into account the length, width, and density of scars). We developed a more objective method that employed creation of vector grid cells and buffers that incorporated the localized ecological impact of scars. Results of spatial and temporal analysis revealed that the polygon approach greatly underestimated the magnitude of scarring. For example, in a single photograph, 7% of seagrass area was lightly scarred according to the polygon method; but light scarring increased to 51% according to grid analysis of the same image. Our results also indicated that propeller scars in Halodule wrightii beds appear to recover in less than three years and ORV tracks have persisted in the wind-tidal flats for at least 38 years. Our approach provides resource managers with procedures for a more objective and efficient assessment of physical disturbances to seagrass and wind-tidal flats caused by boats and ORVs. ?? 2008 by Walter de Gruyter.

  12. Effects of off-road vehicle use on the hydrology and landscape of arid environments in central and southern California

    USGS Publications Warehouse

    Snyder, Charles T.; Frickel, D.G.; Hadley, R.F.; Miller, R.F.

    1976-01-01

    Two widely separated sites in California used for motorcycle hill-climbing were studied to evaluate the impact on the landscape and hydrology. At Panoche Hills in central California, an area formerly used by motorcycles together with an adjacent unused area were monitored from 1971 to 1975. Observations in both areas included measurements of precipitation, runoff, soil moisture, soil bulk density, plant cover, and erosion surveys. At Dove Spring Canyon in souther California erosion was measured on a site that is currently being used for motorcycle hill-climbing. At the Panoche Hills site, the area used by motorcycles produced about eight times as nuch runoff as the unused area. Similarly, sediment yield from the used areas was 857 cubic meters/sq km, while the quantity of sediment from the unused area was not measurable by standard methods. At the Dove Spring Canyon site, which is still being used for hill-climbing, erosion surveys show that degradation in trails has been as much as 0.3 m in the period 1973-75. Compaction of soils and reduction of permeability appears to be the most serious hydrologic impact of motorcycle use at Panoche Hills. Increased bulk density of soils reduces depth of moisture penetration which deprives plants of moisture needed for growth. (Woodard-USGS)

  13. Online Speed Adaptation using Supervised Learning for High-Speed, Off-Road Autonomous Driving

    E-print Network

    Thrun, Sebastian

    Online Speed Adaptation using Supervised Learning for High-Speed, Off-Road Autonomous Driving David. Consider a high-speed (35 mph) autonomous vehi- cle driving off-road through challenging desert ter- rain. The vehicle should drive slowly on terrain that poses substantial risk. However, it should not daw- dle

  14. The Off-Road Axle Detection Sensor (ORADS) is a dual-beam co-axial laser radar (LADAR) sensor that measures lane position and passage of vehicle tires to determine axle

    E-print Network

    Prevedouros, Panos D.

    1 ORADS The Off-Road Axle Detection Sensor (ORADS) is a dual-beam co-axial laser radar (LADAR of the road (e.g., if the road cross-section has a 2% slope and the road is 1% uphill, ORADS must be set Detector Package The setup described in this text consisted of a first generation ORADS laser detector

  15. 77 FR 3123 - Special Regulations, Areas of the National Park System, Cape Hatteras National Seashore-Off-Road...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ...Off-Road Vehicle Management AGENCY: National...National Park System is prohibited...Seashore is part of a dynamic barrier island system. The Seashore...habitat created by dynamic environmental...for the use and management of the...

  16. Moving object prediction for off-road autonomous navigation

    NASA Astrophysics Data System (ADS)

    Madhavan, Raj; Schlenoff, Craig I.

    2003-09-01

    The realization of on- and off-road autonomous navigation of Unmanned Ground Vehicles (UGVs) requires real-time motion planning in the presence of dynamic objects with unknown trajectories. To successfully plan paths and to navigate in an unstructured environment, the UGVs should have the difficult and computationally intensive competency to predict the future locations of moving objects that could interfere with its path. This paper details the development of a combined probabilistic object classification and estimation theoretic framework to predict the future location of moving objects, along with an associated uncertainty measure. The development of a moving object testbed that facilitates the testing of different representations and prediction algorithms in an implementation-independent platform is also outlined.

  17. Target Trailing With Safe Navigation for Maritime Autonomous Surface Vehicles

    NASA Technical Reports Server (NTRS)

    Wolf, Michael; Kuwata, Yoshiaki; Zarzhitsky, Dimitri V.

    2013-01-01

    This software implements a motion-planning module for a maritime autonomous surface vehicle (ASV). The module trails a given target while also avoiding static and dynamic surface hazards. When surface hazards are other moving boats, the motion planner must apply International Regulations for Avoiding Collisions at Sea (COLREGS). A key subset of these rules has been implemented in the software. In case contact with the target is lost, the software can receive and follow a "reacquisition route," provided by a complementary system, until the target is reacquired. The programmatic intention is that the trailed target is a submarine, although any mobile naval platform could serve as the target. The algorithmic approach to combining motion with a (possibly moving) goal location, while avoiding local hazards, may be applicable to robotic rovers, automated landing systems, and autonomous airships. The software operates in JPL s CARACaS (Control Architecture for Robotic Agent Command and Sensing) software architecture and relies on other modules for environmental perception data and information on the predicted detectability of the target, as well as the low-level interface to the boat controls.

  18. NOVEL DATA ANALYSIS TECHNIQUE TO EVALUATE FIELD NOx AND CO2 CONTINUOUS EMISSION DATA, BASED ON THE EVALUATION OF: (1) AN OFF-ROAD DIESEL COMPACTOR RUNNING ON THREE FUEL TYPES AND (2) TWO COMPACTORS RUNNING ON DIESEL FUEL

    E-print Network

    Guerra, Sergio

    2012-12-31

    In spite of being few in number, off-road vehicles have a significant contribution to air pollutants such as NOx and CO2. Engine dynamometer test cycles have been developed in an effort to better characterize the emissions from off-road vehicles...

  19. 77 FR 3123 - Special Regulations, Areas of the National Park System, Cape Hatteras National Seashore-Off-Road...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ...This rule designates off-road vehicle (ORV) routes and authorizes limited ORV use within Cape Hatteras National Seashore (Seashore) in a manner that will protect and preserve natural and cultural resources, provide a variety of safe visitor experiences, and minimize conflicts among various users. Under National Park Service (NPS) general regulations, the operation of motor vehicles off of......

  20. Secondary Organic Aerosol from On- and Off-Road Combustion Emissions: Scientific and Policy Perspectives

    NASA Astrophysics Data System (ADS)

    Gordon, Timothy D.

    Combustion emissions from on-road sources such as light duty gasoline vehicles (LDGV), medium duty diesel vehicles (MDDV) and heavy duty diesel vehicles (HDDV) as well as small off-road engines (SORE) such those used in lawn and garden equipment are a major source of fine particulate matter (PM) pollution in the ambient atmosphere. Existing regulations have restricted direct PM emissions, especially for on-road sources; however, recent studies suggest that organic PM formed from the photo-oxidation of gaseous precursor emissions—so-called secondary organic aerosol (SOA)—contributes at least as much to the overall PM burden as PM "emitted from the tailpipe." A major limitation of many of these studies is that they attempt to induce from the behavior of simple emission surrogates (e.g., vaporized whole fuel) the behavior of actual combustion emissions from real world sources. This research investigates combustion emissions directly. The primary gas- and particle-phase emissions, SOA production and SOA yields from a range of different on-road and off-road combustion sources were characterized. LDGV, MDDV and HDDV were driven on chassis dynamometers over realistic, urban driving cycles. Off-road sources, including 2- and 4-stroke lawn and garden equipment and a diesel transportation refrigeration unit were tested using engine dynamometers operated over certification cycles. For nearly all gasoline engines (LDGV and SOREs), photo-oxidizing dilute combustion emissions for 3 hours produced at least as much SOA as the directly emitted primary PM. SOA increased net PM production for LDGV by a factor of 1-10, depending on the vehicle emission standard. SOA yields were found to increase with newer vehicles, which have lower primary emissions. SOA for diesel vehicles, while still large on an absolute basis, was a smaller fraction of the primary PM emissions (between 10-30%), due to the very high elemental carbon (EC) emissions from vehicles without diesel particulate filters (DPF). Aftertreatment systems utilizing a DPF and a diesel oxidation catalyst essentially eliminated primary PM and SOA. Among the off-road sources, SOA from 2-stroke emissions increased the net PM by roughly a factor of 2. Primary emission and SOA production factors from the various combustion sources tested in this work were combined with fuel consumption data for California's South Coast Air Basin (SoCAB) to determine the impact on the aggregate PM from on- and off-road sources in the region. These estimated impacts were compared to the PM values derived from the regulatory models EMFAC and OFFROAD. Our data indicate that PM from on-road gasoline sources is significantly under-represented by existing emissions models due to the dominant role of SOA. When SOA production is included, newer LDGV are one of the largest sources of PM in SoCAB. Furthermore, LDGV will become an even more important PM source once existing regulations requiring DPF retrofits on both on- and off-road diesel sources are implemented over the next few years. While on-road diesel vehicles are currently an important source of PM based on total fuel consumption, LDGV are responsible for a larger fraction of total PM. The primary and secondary PM contribution of off-road sources also appear to be high, but the magnitude remains highly uncertain, pending further experimental data. Evidence is presented that suggests that existing models may dramatically overpredict primary PM emissions from off-road sources. Regulators are strongly urged to consider the impact of SOA on net PM production.

  1. Dust emission by off-road driving: Experiments on 17 arid soil types, Nevada, USA

    NASA Astrophysics Data System (ADS)

    Goossens, Dirk; Buck, Brenda

    2009-06-01

    Field experiments were conducted in Nellis Dunes Recreational Area (Clark County, Nevada, USA) to investigate emission of dust produced by off-road driving. Experiments were carried out with three types of vehicles: 4-wheelers (quads), dirt bikes (motorcycles) and dune buggies, on 17 soil types characteristic for a desert environment. Tests were done at various driving speeds, and emissions were measured for a large number of grain size fractions. This paper reports the results for two size fractions of emissions: PM10 (particles < 10 ?m) and PM60 (particles < 60 ?m). The latter was considered in this study to be sufficiently representative of the total suspendable fraction (TSP). Off-road driving was found to be a significant source of dust. However, the amounts varied greatly with the type of soil and the characteristics of the top layer. Models predicting emission of dust by off-road driving should thus consider a number of soil parameters and not just one key parameter. Vehicle type and driving speed are additional parameters that affect emission. In general, 4-wheelers produce more dust than dune buggies, and dune buggies, more than dirt bikes. Higher speeds also result in higher emissions. Dust emitted by off-road driving is less coarse than the parent sediment on the road surface. Off-road driving thus results in a progressive coarsening of the top layer. Exceptions to this are silty surfaces with no, or almost no, vegetation. For such surfaces no substantial differences were observed between the grain size distribution of road dust and emitted dust. Typical emission values for off-road driving on dry desert soils are: for sandy areas, 30-40 g km - 1 (PM10) and 150-250 g km - 1 (TSP); for silty areas, 100-200 g km - 1 (PM10) and 600-2000 g km - 1 (TSP); for drainages, 30-40 g km - 1 (PM10) and 100-400 g km - 1 (TSP); and for mixed terrain, 60-100 g km - 1 (PM10) and 300-800 g km - 1 (TSP). These values are for the types of vehicles tested in this study and do not refer to cars or trucks, which produce significantly more dust.

  2. The Prediction of Noise Due to Jet Turbulence Convecting Past Flight Vehicle Trailing Edges

    NASA Technical Reports Server (NTRS)

    Miller, Steven A. E.

    2014-01-01

    High intensity acoustic radiation occurs when turbulence convects past airframe trailing edges. A mathematical model is developed to predict this acoustic radiation. The model is dependent on the local flow and turbulent statistics above the trailing edge of the flight vehicle airframe. These quantities are dependent on the jet and flight vehicle Mach numbers and jet temperature. A term in the model approximates the turbulent statistics of single-stream heated jet flows and is developed based upon measurement. The developed model is valid for a wide range of jet Mach numbers, jet temperature ratios, and flight vehicle Mach numbers. The model predicts traditional trailing edge noise if the jet is not interacting with the airframe. Predictions of mean-flow quantities and the cross-spectrum of static pressure near the airframe trailing edge are compared with measurement. Finally, predictions of acoustic intensity are compared with measurement and the model is shown to accurately capture the phenomenon.

  3. Attitudes and intentions of off-highway vehicle riders toward trail use: implications for forest managers

    USGS Publications Warehouse

    Kuehn, D.M.; D'Luhosch, P. D.; Luzadis, V.A.; Malmsheimer, R.W.; Schuster, R.M.

    2011-01-01

    Management of off-highway vehicles (OHV) in public forest areas requires up-to-date information about the attitudes and intentions of OHV riders toward trail use. A survey of 811 members of the New England Trail Riders Association was conducted in fall 2007; 380 questionnaires were completed and returned. Descriptive statistics and regressions were used to identify relationships between OHV rider attitudes, management preferences, and intentions toward two trail use-related behaviors (i.e., illegal use of trails by OHVs and the creation and/or use of unauthorized trails by OHV riders). Results reveal that the average responding association member has a negative attitude toward the two depreciative behaviors, intends to ride OHVs legally, and slightly prefers indirect over direct forms of management. Significant relationships between intentions and both attitudes and management preferences are identified. Policy and management implications and strategies are discussed. ?? 2011 by the Society of American Foresters.

  4. Off-road motorbike performance analysis using a rear semi-active suspension

    NASA Astrophysics Data System (ADS)

    Lozoya-Santos, Jorge de J.; Cervantes-Muñoz, Damián.; Ramírez Mendoza, Ricardo

    2015-04-01

    The topic of this paper is the analysis of a control system for a semi active rear suspension in an off-road 2-wheel vehicle. Several control methods are studied, as well as the recently proposed Frequency Estimation Based (FEB) algorithm. The test motorcycle dynamics, as well as the passive, semi active, and the algorithm controlled shock absorber models are loaded into BikeSim, a professional two-wheeled vehicle simulation software, and tested in several road conditions. The results show a detailed comparison of the theoretical performance of the different control approaches in a novel environment for semi active dampers.

  5. Finite element analysis of the effect of up-armouring on the off-road braking and sharp-turn performance

    E-print Network

    Grujicic, Mica

    -armouring employed to improve vehicle blast and ballistic pro- tection performance and survivability. The results and ramifications of lightweight up-armouring in providing the needed level of blast and/or ballistic performance-mobility multi-purpose wheeled vehicle, off-road vehicle performance, finite element modelling and simulations

  6. Daytime Water Detection by Fusing Multiple Cues for Autonomous Off-Road Navigation

    NASA Technical Reports Server (NTRS)

    Rankin, A. L.; Matthies, L. H.; Huertas, A.

    2004-01-01

    Detecting water hazards is a significant challenge to unmanned ground vehicle autonomous off-road navigation. This paper focuses on detecting the presence of water during the daytime using color cameras. A multi-cue approach is taken. Evidence of the presence of water is generated from color, texture, and the detection of reflections in stereo range data. A rule base for fusing water cues was developed by evaluating detection results from an extensive archive of data collection imagery containing water. This software has been implemented into a run-time passive perception subsystem and tested thus far under Linux on a Pentium based processor.

  7. The Application of Design Schemata in Off-road Robotics

    E-print Network

    Berns, Karsten

    -oriented and perception-oriented concepts for the devel- opment of robot control systems with the aim to close1 The Application of Design Schemata in Off-road Robotics Bernd-Helge Schäfer (Member, IEEE are introduced, and their application in the control system of a real robot is demonstrated using the example

  8. Fuel Used for Off-Road Recreation: A Reassessment of the Fuel Use Model

    E-print Network

    Fuel Used for Off-Road Recreation: A Reassessment of the Fuel Use Model Stacy C. Davis Lorena F. Truett Patricia S. Hu #12;ORNL/TM-1999/100 Fuel Used for Off-Road Recreation: A Reassessment of the Fuel.S. Department of Energy under Contract No. DE-AC05-96OR22464 #12;#12;Fuel Used for Off-Road Recreation

  9. Research and Development for Off-Road Fuel Cell Applications U.S. Department of Energy Grant DE-FG36-04GO14303 - Final Report

    SciTech Connect

    Hicks, Michael; Erickson, Paul; Lawrence, Richard; Tejaswi, Arun; Brum, Magdalena

    2013-04-30

    Off-road concerns are related to the effects of shock and vibration and air quality on fuel cell power requirements. Mechanical stresses on differing material makeup and mass distribution within the system may render some components susceptible to impulse trauma while others may show adverse effects from harmonic disturbances or broad band mechanical agitation. One of the recognized challenges in fuel cell systems air purification is in providing a highly efficient particulate and chemical filter with minimal pressure drop. PEM integrators do not want additional parasitic loads added to the system as compensation for a highly efficient yet highly restrictive filter. Additionally, there is challenge in integrating multiple functions into a single air intake module tasked with effectively filtering high dust loads, diesel soot, pesticides, ammonias, and other anticipated off-road contaminants. This project has investigated both off-road associated issues cumulating in the prototype build and testing of two light duty off-road vehicles with integrated fuel cell power plant systems.

  10. Physiological Demands of Simulated Off-Road Cycling Competition.

    PubMed

    Smekal, Gerhard; von Duvillard, Serge P; Hörmandinger, Maximilian; Moll, Roland; Heller, Mario; Pokan, Rochus; Bacharach, David W; LeMura, Linda M; Arciero, Paul

    2015-12-01

    The purpose of the study was to measure the demands of off-road cycling via portable spirometry, leg-power output (PO), heart rate (HR) and blood lactate (BLa) concentration. Twenty-four male competitive cyclists (age: 29±7.2 yrs, height: 1.79 ± 0.05 m, body mass: 70.0 ± 4.9 kg, VO2peak: 64.9 ± 7.5 ml·kg(-1)·min(-1)) performed simulated mountain bike competitions (COMP) and laboratory tests (LabT). From LabT, we determined maximal workload and first and second ventilatory thresholds (VT1, VT2). A high-performance athlete (HPA) was used for comparison with three groups of subjects with different sport-specific performance levels. Load profiles of COMP were also investigated during uphill, flat and downhill cycling. During the COMP, athletes achieved a mean oxygen uptake (VO2COMP) of 57.0 ± 6.8 ml·kg(-1)·min(-1) vs. 71.1 ml·kg(-1)·min(-1) for the HPA. The POCOMP was 2.66±0.43 W·kg(-1) and 3.52 W·kg(-1) for the HPA. POCOMP, VO2COMP and HRCOMP were compared to corresponding variables at the VT2 of LabT. LabT variables correlated with racing time (RTCOMP) and POCOMP (p < 0.01 to <0.001; r-0.59 to -0.80). The VO2peak (LabT) accounted for 65% of variance of a single COMP test. VO2COMP, POCOMP and also endurance variables measured from LabTs were found as important determinants for cross-country performance. The high average VO2COMP indicates that a high aerobic capacity is a prerequisite for successful COMP. Findings derived from respiratory gas measures during COMPs might be useful when designing mountain bike specific training. Key pointsCross- country cycling is characterized by high oxygen costs due to the high muscle mass simultaneously working to fulfill the demands of this kind of sports.Heart rate and blood lactate concentration measures are not sensitive enough to assess the energy requirements of COMP. Therefore, respiratory gas and power output measures are helpful to provide new information to physiological profile of cross- country cycling.An excellent cycling-specific capacity is a prerequisite for successful off-road cycling.Data determined from LabT might be utilized to describe semi-specific abilities of MB- athletes on a cycle ergometer, while data originating from COMP might be useful when designing a mountain bike specific training. PMID:26664277

  11. Physiological Demands of Simulated Off-Road Cycling Competition

    PubMed Central

    Smekal, Gerhard; von Duvillard, Serge P.; Hörmandinger, Maximilian; Moll, Roland; Heller, Mario; Pokan, Rochus; Bacharach, David W.; LeMura, Linda M.; Arciero, Paul

    2015-01-01

    The purpose of the study was to measure the demands of off-road cycling via portable spirometry, leg-power output (PO), heart rate (HR) and blood lactate (BLa) concentration. Twenty-four male competitive cyclists (age: 29±7.2 yrs, height: 1.79 ± 0.05 m, body mass: 70.0 ± 4.9 kg, VO2peak: 64.9 ± 7.5 ml·kg-1·min-1) performed simulated mountain bike competitions (COMP) and laboratory tests (LabT). From LabT, we determined maximal workload and first and second ventilatory thresholds (VT1, VT2). A high-performance athlete (HPA) was used for comparison with three groups of subjects with different sport-specific performance levels. Load profiles of COMP were also investigated during uphill, flat and downhill cycling. During the COMP, athletes achieved a mean oxygen uptake (VO2COMP) of 57.0 ± 6.8 ml·kg-1·min-1 vs. 71.1 ml·kg-1·min-1 for the HPA. The POCOMP was 2.66±0.43 W·kg-1 and 3.52 W·kg-1 for the HPA. POCOMP, VO2COMP and HRCOMP were compared to corresponding variables at the VT2 of LabT. LabT variables correlated with racing time (RTCOMP) and POCOMP (p < 0.01 to <0.001; r-0.59 to -0.80). The VO2peak (LabT) accounted for 65% of variance of a single COMP test. VO2COMP, POCOMP and also endurance variables measured from LabTs were found as important determinants for cross-country performance. The high average VO2COMP indicates that a high aerobic capacity is a prerequisite for successful COMP. Findings derived from respiratory gas measures during COMPs might be useful when designing mountain bike specific training. Key points Cross- country cycling is characterized by high oxygen costs due to the high muscle mass simultaneously working to fulfill the demands of this kind of sports. Heart rate and blood lactate concentration measures are not sensitive enough to assess the energy requirements of COMP. Therefore, respiratory gas and power output measures are helpful to provide new information to physiological profile of cross- country cycling. An excellent cycling-specific capacity is a prerequisite for successful off-road cycling. Data determined from LabT might be utilized to describe semi-specific abilities of MB- athletes on a cycle ergometer, while data originating from COMP might be useful when designing a mountain bike specific training. PMID:26664277

  12. Physiological characteristics of top level off-road motorcyclists

    PubMed Central

    Gobbi, A; Francisco, R; Tuy, B; Kvitne, R; Nakamura, N

    2005-01-01

    Objectives: The study aims to analyse the physiological characteristics of top level off-road motocross, enduro, and desert rally motorcyclists to facilitate the design of a specific training program. Results: The physical demands of the various races appear to influence the development of distinct musculoskeletal characteristics, as well as aerobic and anaerobic metabolism. Motocross riders have more muscle mass, higher isokinetic handgrip strength, and greater aerobic power than enduro and desert rally riders. However, there are no significant anthropometric and physiological differences between desert rally and enduro riders. Desert rally riders tend to be overweight with maximum aerobic power similar to that of healthy individuals. The mechanical characteristics of the motorcycle and the technical and tactical skills of the riders seem to be more important for race success than the metabolic capabilities of the rider. Conclusions: Desert rally and enduro riders present similar anthropometric and physiological characteristics. Both have a maximum aerobic power similar to that of healthy normal individuals, although desert rally riders tend to be overweight. Motocross riders on the other hand, have more muscle mass, more strength, and greater aerobic power. The differences observed suggest the need for a specific training program to address the requirements of different riders to reduce the possibility of injury. PMID:16306501

  13. Effects of all-terrain vehicle trails on stream channel characteristics, Ouachita National Forest, Arkansas 

    E-print Network

    Rohrer, Deven Michelle

    2001-01-01

    impact streams to a lesser extent than ATV trails. The effects of roads and trails on stream pool characteristics were illustrated using Geographic Information Systems. These findings have important implications for the ecological integrity of stream...

  14. Evaluation of stereo vision obstacle detection algorithms for off-road autonomous navigation

    NASA Technical Reports Server (NTRS)

    Rankin, Arturo; Huertas, Andres; Matthies, Larry

    2005-01-01

    Reliable detection of non-traversable hazards is a key requirement for off-road autonomous navigation. A detailed description of each obstacle detection algorithm and their performance on the surveyed obstacle course is presented in this paper.

  15. Mobility Erosion: High speed motion safety for mobile robots operating in off-road terrain

    E-print Network

    Karumanchi, Sisir B.

    This paper addresses the problem of ensuring mobile robot motion safety when reacting to soft and hard hazards in a static environment. The work is aimed at off-road navigation for mobile ground robots where soft hazards ...

  16. Night-time negative obstacle detection for off-road autonomous navigation

    NASA Astrophysics Data System (ADS)

    Rankin, Arturo L.; Huertas, Andres; Matthies, Larry H.

    2007-04-01

    Detecting negative obstacles (ditches, holes, wadis, and other depressions) is one of the most difficult problems in perception for unmanned ground vehicle (UGV) off-road autonomous navigation. One reason for this is that the width of the visible portion of a negative obstacle may only span a few pixels at the stopping distance for vehicle speeds UGV programs aspire to operate at (up to 50kph). The problem can be further compounded when negative obstacles are obscured by vegetation or when negative obstacles are embedded in undulating terrain. Because of the variety of appearances of negative obstacles, a multi-cue detection approach is desired. In previous nighttime negative obstacle detection work, we have described combining geometry based cues from stereo range data and a thermal signature based cue from thermal infrared imagery. Thermal signature is a powerful cue during the night since the interiors of negative obstacles generally remain warmer than surrounding terrain throughout the night. In this paper, we further couple the thermal signature based cue and geometry based cues from stereo range data for nighttime negative obstacle detection. Edge detection is used to generate closed contour candidate negative obstacle regions that are geometrically filtered to determine if they lie within the ground plane. Cues for negative obstacles from thermal signature, geometry-based analysis of range images, and geometry-based analysis of terrain maps are fused. The focus of this work is to increase the range at which UGVs can reliably detect negative obstacles on cross-country terrain, thereby increasing the speed at which UGVs can safely operate.

  17. Factors affecting the impact of off-road driving on soils in an area in the Kruger National Park, South Africa.

    PubMed

    Nortjé, Gerhardus Petrus; van Hoven, Wouter; Laker, Michiel C

    2012-12-01

    Studies on the effects of off-road driving on soils were conducted in the Makuleke Contractual Park of the Kruger National Park. The studies were conducted on three different soils with different textures and soil compactibilities. Traffic pressure was applied with a game drive vehicle loaded with 11 sand bags, each weighing 70 kg. This gave a total vehicle mass of 3,795 kg, simulating a vehicle fully laden with tourists. The study included: (i) comparing of the effects of four different tyre pressures; (ii) comparing the effects of 1-3 vehicle passes over the same tyre tracks; (iii) comparison of traffic effects under dry and wet soil moisture conditions, on soil compaction, respectively. After each pass penetration resistances were measured (a) on the tyre tracks, (b) between the tyre tracks and (c) at different distances outside the tyre tracks. As expected, vehicular traffic caused soil compaction below the wheel tracks. Lower tyre pressures caused less compaction than higher tyre pressures. Fewer vehicle passes also caused less compaction than more passes on the same tracks, but most compaction occurred during the first pass. Thus, driving on the same tracks more than once is less damaging than driving once on different tracks. Controlled traffic should be considered when developing management strategies for off-road driving in wildlife protected areas. PMID:23079698

  18. Factors Affecting the Impact of Off-Road Driving on Soils in an Area in the Kruger National Park, South Africa

    NASA Astrophysics Data System (ADS)

    Nortjé, Gerhardus Petrus; van Hoven, Wouter; Laker, Michiel C.

    2012-12-01

    Studies on the effects of off-road driving on soils were conducted in the Makuleke Contractual Park of the Kruger National Park. The studies were conducted on three different soils with different textures and soil compactibilities. Traffic pressure was applied with a game drive vehicle loaded with 11 sand bags, each weighing 70 kg. This gave a total vehicle mass of 3,795 kg, simulating a vehicle fully laden with tourists. The study included: (i) comparing of the effects of four different tyre pressures; (ii) comparing the effects of 1-3 vehicle passes over the same tyre tracks; (iii) comparison of traffic effects under dry and wet soil moisture conditions, on soil compaction, respectively. After each pass penetration resistances were measured (a) on the tyre tracks, (b) between the tyre tracks and (c) at different distances outside the tyre tracks. As expected, vehicular traffic caused soil compaction below the wheel tracks. Lower tyre pressures caused less compaction than higher tyre pressures. Fewer vehicle passes also caused less compaction than more passes on the same tracks, but most compaction occurred during the first pass. Thus, driving on the same tracks more than once is less damaging than driving once on different tracks. Controlled traffic should be considered when developing management strategies for off-road driving in wildlife protected areas.

  19. Stereo-vision-based terrain mapping for off-road autonomous navigation

    NASA Astrophysics Data System (ADS)

    Rankin, Arturo L.; Huertas, Andres; Matthies, Larry H.

    2009-05-01

    Successful off-road autonomous navigation by an unmanned ground vehicle (UGV) requires reliable perception and representation of natural terrain. While perception algorithms are used to detect driving hazards, terrain mapping algorithms are used to represent the detected hazards in a world model a UGV can use to plan safe paths. There are two primary ways to detect driving hazards with perception sensors mounted to a UGV: binary obstacle detection and traversability cost analysis. Binary obstacle detectors label terrain as either traversable or non-traversable, whereas, traversability cost analysis assigns a cost to driving over a discrete patch of terrain. In uncluttered environments where the non-obstacle terrain is equally traversable, binary obstacle detection is sufficient. However, in cluttered environments, some form of traversability cost analysis is necessary. The Jet Propulsion Laboratory (JPL) has explored both approaches using stereo vision systems. A set of binary detectors has been implemented that detect positive obstacles, negative obstacles, tree trunks, tree lines, excessive slope, low overhangs, and water bodies. A compact terrain map is built from each frame of stereo images. The mapping algorithm labels cells that contain obstacles as nogo regions, and encodes terrain elevation, terrain classification, terrain roughness, traversability cost, and a confidence value. The single frame maps are merged into a world map where temporal filtering is applied. In previous papers, we have described our perception algorithms that perform binary obstacle detection. In this paper, we summarize the terrain mapping capabilities that JPL has implemented during several UGV programs over the last decade and discuss some challenges to building terrain maps with stereo range data.

  20. Stereo Vision Based Terrain Mapping for Off-Road Autonomous Navigation

    NASA Technical Reports Server (NTRS)

    Rankin, Arturo L.; Huertas, Andres; Matthies, Larry H.

    2009-01-01

    Successful off-road autonomous navigation by an unmanned ground vehicle (UGV) requires reliable perception and representation of natural terrain. While perception algorithms are used to detect driving hazards, terrain mapping algorithms are used to represent the detected hazards in a world model a UGV can use to plan safe paths. There are two primary ways to detect driving hazards with perception sensors mounted to a UGV: binary obstacle detection and traversability cost analysis. Binary obstacle detectors label terrain as either traversable or non-traversable, whereas, traversability cost analysis assigns a cost to driving over a discrete patch of terrain. In uncluttered environments where the non-obstacle terrain is equally traversable, binary obstacle detection is sufficient. However, in cluttered environments, some form of traversability cost analysis is necessary. The Jet Propulsion Laboratory (JPL) has explored both approaches using stereo vision systems. A set of binary detectors has been implemented that detect positive obstacles, negative obstacles, tree trunks, tree lines, excessive slope, low overhangs, and water bodies. A compact terrain map is built from each frame of stereo images. The mapping algorithm labels cells that contain obstacles as no-go regions, and encodes terrain elevation, terrain classification, terrain roughness, traversability cost, and a confidence value. The single frame maps are merged into a world map where temporal filtering is applied. In previous papers, we have described our perception algorithms that perform binary obstacle detection. In this paper, we summarize the terrain mapping capabilities that JPL has implemented during several UGV programs over the last decade and discuss some challenges to building terrain maps with stereo range data.

  1. A video based run-off-road training program with practice and evaluation in a simulator.

    PubMed

    Freeman, Paul; Neyens, David M; Wagner, John; Switzer, Fred; Alexander, Kim; Pidgeon, Philip

    2015-09-01

    A run-off-road (ROR) event occurs when one or more of a vehicle's wheels leaves the roadway and begins to travel on the surface or shoulder adjacent to the road. Despite various countermeasures, ROR crashes continue to yield a large number of fatalities and injuries. Infrastructure-based solutions do not directly address the critical factor of driver performance preceding and during an ROR event. In this study, a total of 75 individuals participated in a pre-post experiment to examine the effect of a training video on improving driver performance during a set of simulated ROR scenarios (e.g., on a high speed highway, a horizontal curve, and a residential rural road). In each scenario, the vehicle was unexpectedly forced into an ROR scenario for which the drivers were instructed to recover as safely as possible. The treatment group then watched a custom ROR training video while the control group viewed a placebo video. The participants then drove the same simulated ROR scenarios. The results suggest that the training video had a significant positive effect on drivers' steering response on all three roadway conditions as well as improvements in vehicle stability, subjectively rated demand on the driver, and self-evaluated performance in the highway scenario. Under the highway conditions, the treatment group reduced the frequency of spinouts from 70% in the pre-training events to 16% in the post-training events (?(2)(1)=23.32, p<0.001) with no significant improvement found for the control group. In the horizontal curve, spinouts were reduced for the treatment group from 50% in the pre-training events to 30% in the post-training events (?(2)(1)=8.45, p=0.004) with the control group also not showing any significant improvement. The results of this study suggest that even a short video about recovering from ROR events can significantly influence a driver's ability to recover. It is possible that additional training may have further benefits in recovering from ROR events. PMID:26005742

  2. COMPARISON OF ON AND OFF ROAD DIESEL EXHAUST SOURCES ON THE SUSCEPTIBILITY TO AN INFLUENZA INFECTION.

    EPA Science Inventory

    Diesel exhaust (DE), a major component of urban air pollution, and its modulatory role in human susceptibility to respiratory infections is of great concern. The purpose of this study was to evaluate the effects of on- and off-road sources of DE exposure on the severity of an ...

  3. Effect of drivers' age and push button locations on visual time off road, steering wheel deviation and safety perception.

    PubMed

    Dukic, T; Hanson, L; Falkmer, T

    2006-01-15

    The study examined the effects of manual control locations on two groups of randomly selected young and old drivers in relation to visual time off road, steering wheel deviation and safety perception. Measures of visual time off road, steering wheel deviations and safety perception were performed with young and old drivers during real traffic. The results showed an effect of both driver's age and button location on the dependent variables. Older drivers spent longer visual time off road when pushing the buttons and had larger steering wheel deviations. Moreover, the greater the eccentricity between the normal line of sight and the button locations, the longer the visual time off road and the larger the steering wheel deviations. No interaction effect between button location and age was found with regard to visual time off road. Button location had an effect on perceived safety: the further away from the normal line of sight the lower the rating. PMID:16393805

  4. EMS-Vision: combining on- and off-road driving

    NASA Astrophysics Data System (ADS)

    Gregor, Rudolf; Luetzeler, Michael; Dickmanns, Ernst D.

    2001-09-01

    In the past, work at the Universitat der Bundeswehr Muenchen (UBM) has been focused on autonomous road vehicles. During the last four years the Expectation-based Multi-focal Saccadic Vision (EMS-Vision) system has been developed and implemented. EMS-Vision is the 3rd generation dynamic vision system following the 4-D approach. The explicit representation of the own capabilities combined with a complex control and information flow allows the implementation of decision units for goal oriented activation of locomotion and perception. Due to this general approach and in contrast to former UBM systems that were specially designed and optimized for certain limited scenarios and domains, e.g., road following on Autobahnen, the EMS-Vision system can handle complex driving missions spanning multiple domains. It has been realized on a decentralized parallel hardware structure, exclusively built of commercial off-the-shelf components, in both UBM test vehicles VaMoRs and VaMP. Results from an autonomously performed mission on the UBM campus are discussed.

  5. A Fuel-Based Assessment of On-Road and Off-Road Mobile Source Emission Trends

    NASA Astrophysics Data System (ADS)

    Dallmann, T. R.; Harley, R. A.

    2009-12-01

    Mobile sources contribute significantly to emissions of nitrogen oxides (NOx) and fine particulate matter (PM2.5) in the United States. These emissions lead to a variety of environmental concerns including adverse human health effects and climate change. In the electric power sector, sulfur dioxide (SO2) and NOx emissions from power plants are measured directly using continuous emission monitoring systems. In contrast for mobile sources, statistical models are used to estimate average emissions from a very large and diverse population of engines. Despite much effort aimed at improving them, mobile source emission inventories continue to have large associated uncertainties. Alternate methods are needed to help evaluate estimates of mobile source emissions and quantify and reduce the associated uncertainties. In this study, a fuel-based approach is used to estimate emissions from mobile sources, including on-road and off-road gasoline and diesel engines. In this approach, engine activity is measured by fuel consumed (in contrast EPA mobile source emission models are based on vehicle km of travel and total amount of engine work output for on-road and off-road engines, respectively). Fuel consumption is defined in this study based on highway fuel tax reports for on-road engines, and from surveys of fuel wholesalers who sell tax-exempt diesel fuel for use in various off-road sectors such as agriculture, construction, and mining. Over the decade-long time period (1996-2006) that is the focus of the present study, national sales of taxable gasoline and diesel fuel intended for on-road use increased by 15 and 43%, respectively. Diesel fuel use by off-road equipment increased by about 20% over the same time period. Growth in fuel consumption offset some of the reductions in pollutant emission factors that occurred during this period. This study relies on in-use measurements of mobile source emission factors, for example from roadside and tunnel studies, remote sensing, and plume capture experiments. Extensive in-use emissions data are available for NOx, especially for on-road engines. Measurements of exhaust PM2.5 emission factors are sparse in comparison. For NOx, there have been dramatic (factor of 2) decreases in emission factors for on-road gasoline engines between 1996 and 2006, due to use of improved catalytic converters on most engines. In contrast, diesel NOx emission factors decreased more gradually over the same time period. Exhaust PM2.5 emission factors appear to have decreased for most engine categories, but emission uncertainties are large for this pollutant. Pollutant emissions were estimated by combining fuel sales with emission factors expressed per unit of fuel burned. Diesel engines are the dominant mobile source of both NOx and PM2.5; the diesel contribution to NOx has increased over time as gasoline engine emissions have declined. Comparing fuel-based emission estimates with EPA’s national emission inventory led to the following conclusions: (1) total emissions of both NOx and PM2.5 estimated by two different methods were similar, (2) the distribution of source contributions to these totals differ significantly, with higher relative contributions coming from on-road diesel engines in this study compared to EPA.

  6. Primary gas- and particle-phase emissions and secondary organic aerosol production from gasoline and diesel off-road engines.

    PubMed

    Gordon, Timothy D; Tkacik, Daniel S; Presto, Albert A; Zhang, Mang; Jathar, Shantanu H; Nguyen, Ngoc T; Massetti, John; Truong, Tin; Cicero-Fernandez, Pablo; Maddox, Christine; Rieger, Paul; Chattopadhyay, Sulekha; Maldonado, Hector; Maricq, M Matti; Robinson, Allen L

    2013-12-17

    Dilution and smog chamber experiments were performed to characterize the primary emissions and secondary organic aerosol (SOA) formation from gasoline and diesel small off-road engines (SOREs). These engines are high emitters of primary gas- and particle-phase pollutants relative to their fuel consumption. Two- and 4-stroke gasoline SOREs emit much more (up to 3 orders of magnitude more) nonmethane organic gases (NMOGs), primary PM and organic carbon than newer on-road gasoline vehicles (per kg of fuel burned). The primary emissions from a diesel transportation refrigeration unit were similar to those of older, uncontrolled diesel engines used in on-road vehicles (e.g., premodel year 2007 heavy-duty diesel trucks). Two-strokes emitted the largest fractional (and absolute) amount of SOA precursors compared to diesel and 4-stroke gasoline SOREs; however, 35-80% of the NMOG emissions from the engines could not be speciated using traditional gas chromatography or high-performance liquid chromatography. After 3 h of photo-oxidation in a smog chamber, dilute emissions from both 2- and 4-stroke gasoline SOREs produced large amounts of semivolatile SOA. The effective SOA yield (defined as the ratio of SOA mass to estimated mass of reacted precursors) was 2-4% for 2- and 4-stroke SOREs, which is comparable to yields from dilute exhaust from older passenger cars and unburned gasoline. This suggests that much of the SOA production was due to unburned fuel and/or lubrication oil. The total PM contribution of different mobile source categories to the ambient PM burden was calculated by combining primary emission, SOA production and fuel consumption data. Relative to their fuel consumption, SOREs are disproportionately high total PM sources; however, the vastly greater fuel consumption of on-road vehicles renders them (on-road vehicles) the dominant mobile source of ambient PM in the Los Angeles area. PMID:24261886

  7. Target Trailing With Safe Navigation With Colregs for Maritime Autonomous Surface Vehicles

    NASA Technical Reports Server (NTRS)

    Kuwata, Yoshiaki (Inventor); Wolf, Michael T. (Inventor); Zarzhitsky, Dimitri V. (Inventor); Aghazarian, Hrand (Inventor); Huntsberger, Terrance L. (Inventor); Howard, Andrew B. (Inventor)

    2014-01-01

    Systems and methods for operating autonomous waterborne vessels in a safe manner. The systems include hardware for identifying the locations and motions of other vessels, as well as the locations of stationary objects that represent navigation hazards. By applying a computational method that uses a maritime navigation algorithm for avoiding hazards and obeying COLREGS using Velocity Obstacles to the data obtained, the autonomous vessel computes a safe and effective path to be followed in order to accomplish a desired navigational end result, while operating in a manner so as to avoid hazards and to maintain compliance with standard navigational procedures defined by international agreement. The systems and methods have been successfully demonstrated on water with radar and stereo cameras as the perception sensors, and integrated with a higher level planner for trailing a maneuvering target.

  8. Modeling Aggressive Maneuvers on Loose Surfaces: The Cases of Trail-Braking and Pendulum-Turn

    E-print Network

    Tsiotras, Panagiotis

    for path planning of ground vehicles. For off-road aggressive driving scenarios the maneuver repertoire with additional constraints. I. INTRODUCTION The state of the art in autonomous ground vehicles was perhaps of autonomous ground vehicles will be able to travel autonomously such long distances faster than these moderate

  9. Flight and Integrated Testing: Blazing the Trail for the Ares Launch Vehicles

    NASA Technical Reports Server (NTRS)

    Taylor, James L.; Cockrell, Charlie; Robinson, Kimberly; Tuma, Margaret L.; Flynn, Kevin C.; Briscoe, Jeri M.

    2007-01-01

    It has been 30 years since the United States last designed and built a human-rated launch vehicle. The National Aeronautics and Space Administration (NASA) has marshaled unique resources from the government and private sectors that will carry the next generation of astronauts into space safer and more efficiently than ever and send them to the Moon to develop a permanent outpost. NASA's Flight and Integrated Test Office (FITO) located at Marshall Space Flight Center and the Ares I-X Mission Management Office have primary responsibility for developing and conducting critical ground and flight tests for the Ares I and Ares V launch vehicles. These tests will draw upon Saturn and the Space Shuttle experiences, which taught the value of using sound systems engineering practices, while also applying aerospace best practices such as "test as you fly" and other lessons learned. FITO will use a variety of methods to reduce the technical, schedule, and cost risks of flying humans safely aboard a launch vehicle.

  10. Ballistic motion of dust particles in the Lunar Roving Vehicle dust trails

    NASA Astrophysics Data System (ADS)

    Hsu, Hsiang-Wen; Horányi, Mihály

    2012-05-01

    We have selected video images from the Apollo 16 mission and analyzed the motion of dust clouds kicked up by the wheels of the Lunar Roving Vehicle (LRV). Applying the equations of ballistic motion, we estimate both the velocity of the dust and the gravitational field strength at the lunar surface. From measurements of the rotation of an LRV wheel, we estimate the speed of the LRV. Such exercises can be useful when discussing ballistic trajectories and angular motion in a high school or introductory level college physics class.

  11. 43 CFR 423.40 - Vehicles.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... addition to the regulations in this part, the regulations governing off-road-vehicle use in 43 CFR part 420... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Vehicles. 423.40 Section 423.40 Public... Vehicles. (a) When operating a vehicle on Reclamation lands and Reclamation projects, you must comply...

  12. Experimental Design Considerations for Establishing an Off-Road, Habitat-Specific Bird Monitoring Program Using Point-Counts1

    E-print Network

    Experimental Design Considerations for Establishing an Off-Road, Habitat-Specific Bird Monitoring Program Using Point-Counts1 JoAnn M. Hanowski and Gerald J. Niemi2 Abstract: We established bird and to assess within-stand and between-stand variation for a variety of bird parameters. Data gathered in 1991

  13. Detection and Classification of Motor Vehicle Noise in a Forested Landscape

    NASA Astrophysics Data System (ADS)

    Brown, Casey L.; Reed, Sarah E.; Dietz, Matthew S.; Fristrup, Kurt M.

    2013-11-01

    Noise emanating from human activity has become a common addition to natural soundscapes and has the potential to harm wildlife and erode human enjoyment of nature. In particular, motor vehicles traveling along roads and trails produce high levels of both chronic and intermittent noise, eliciting varied responses from a wide range of animal species. Anthropogenic noise is especially conspicuous in natural areas where ambient background sound levels are low. In this article, we present an acoustic method to detect and analyze motor vehicle noise. Our approach uses inexpensive consumer products to record sound, sound analysis software to automatically detect sound events within continuous recordings and measure their acoustic properties, and statistical classification methods to categorize sound events. We describe an application of this approach to detect motor vehicle noise on paved, gravel, and natural-surface roads, and off-road vehicle trails in 36 sites distributed throughout a national forest in the Sierra Nevada, CA, USA. These low-cost, unobtrusive methods can be used by scientists and managers to detect anthropogenic noise events for many potential applications, including ecological research, transportation and recreation planning, and natural resource management.

  14. 36 CFR 261.55 - National Forest System trails.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false National Forest System trails... PROHIBITIONS Prohibitions in Areas Designated by Order § 261.55 National Forest System trails. When provided by... National Forest System trail: (a) Being on a trail. (b) Using any type of vehicle prohibited by the...

  15. 36 CFR 261.55 - National Forest System trails.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false National Forest System trails... PROHIBITIONS Prohibitions in Areas Designated by Order § 261.55 National Forest System trails. When provided by... National Forest System trail: (a) Being on a trail. (b) Using any type of vehicle prohibited by the...

  16. 36 CFR 261.55 - National Forest System trails.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false National Forest System trails... PROHIBITIONS Prohibitions in Areas Designated by Order § 261.55 National Forest System trails. When provided by... National Forest System trail: (a) Being on a trail. (b) Using any type of vehicle prohibited by the...

  17. 36 CFR 261.55 - National Forest System trails.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false National Forest System trails... PROHIBITIONS Prohibitions in Areas Designated by Order § 261.55 National Forest System trails. When provided by... National Forest System trail: (a) Being on a trail. (b) Using any type of vehicle prohibited by the...

  18. 36 CFR 261.55 - National Forest System trails.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false National Forest System trails... PROHIBITIONS Prohibitions in Areas Designated by Order § 261.55 National Forest System trails. When provided by... National Forest System trail: (a) Being on a trail. (b) Using any type of vehicle prohibited by the...

  19. 36 CFR 212.51 - Designation of roads, trails, and areas.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...Designation of roads, trails, and areas. 212.51 Section 212.51 Parks, Forests...Designation of Roads, Trails, and Areas for Motor Vehicle Use § 212.51 Designation of roads, trails, and areas. (a) General. Motor...

  20. 36 CFR 212.51 - Designation of roads, trails, and areas.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Designation of roads, trails, and areas. 212.51 Section 212.51 Parks, Forests...Designation of Roads, Trails, and Areas for Motor Vehicle Use § 212.51 Designation of roads, trails, and areas. (a) General. Motor...

  1. 36 CFR 212.51 - Designation of roads, trails, and areas.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...Designation of roads, trails, and areas. 212.51 Section 212.51 Parks, Forests...Designation of Roads, Trails, and Areas for Motor Vehicle Use § 212.51 Designation of roads, trails, and areas. (a) General. Motor...

  2. 36 CFR 212.51 - Designation of roads, trails, and areas.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...Designation of roads, trails, and areas. 212.51 Section 212.51 Parks, Forests...Designation of Roads, Trails, and Areas for Motor Vehicle Use § 212.51 Designation of roads, trails, and areas. (a) General. Motor...

  3. 36 CFR 212.51 - Designation of roads, trails, and areas.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...Designation of roads, trails, and areas. 212.51 Section 212.51 Parks, Forests...Designation of Roads, Trails, and Areas for Motor Vehicle Use § 212.51 Designation of roads, trails, and areas. (a) General. Motor...

  4. Winding Trail 

    E-print Network

    Unknown

    2011-09-05

    TRAIL SYSTEM PRIORITIES PLAN 125 TRANSPORTATION PROJECTS PRIORITIES PLAN 126 TRANSPORTATION PROJECTS INPUT 127 CHAPTER 6 FINANCIAL PLAN 141 FINANCIAL SUMMARY, ASSUMPTIONS, AND AVAILABLE TOOLS 141 PROPOSED REVENUES 142 PROJECTED EXPENDITURES 146...

  5. Magneto-rheological fluid shock absorber for suspension of an off-road motorcycle: a theoretical study

    NASA Astrophysics Data System (ADS)

    Ericksen, Everet O.; Gordaninejad, Faramarz

    2000-06-01

    This work presents a theoretical model for the damping force of a magneto-rheological fluid (MRF) shock absorber of an off-road motorcycle. The Bingham plastic model and a 3D electromagnetic finite-element analysis are employed to develop a theoretical model to estimate the damping force of a MRF shock absorber. The mode is based on the physical parameters of the device as well as the properties of the fluid, making a valuable tool in shock absorber design for a particular application. By comparing the theoretical and experimental results, it is demonstrated that the model accurately predicts the damping force.

  6. Three-way catalyst technology for off-road equipment powered by gasoline and LPG engines. Final report

    SciTech Connect

    White, J.J.; Ingalls, M.N.; Carroll, J.N.; Chan, L.M.

    1999-04-01

    Research was done to demonstrate the feasibility of using closed-loop three-way catalyst (TWC) technology in off-road large spark-ignited (LSI) engine applications to meet California State Implementation Plan (SIP) emission reduction goals. Available technology was investigated for applicability to engines in this category. Appropriate test cycles were recommended, and five representative engines were selected and baseline emission tested. Total feasible emission reductions were calculated. The retail price equivalent (RPE) for the recommended emission control technology was determined, and cost-effectiveness was calculated. Emission standards necessary to meet SIP goals were recommended.

  7. An Autonomous Off-Road Robot Based on Integrative Technologies Orlando J. Hernandez

    E-print Network

    Hernandez, Orlando

    infrastructure for unmanned ground vehicle. Part of the design is an interactive graphical simulation interface Research Projects Agency (DARPA) of U.S.A initiated Grand Challenge in 2004, which is an annual autonomous-ground-vehicle-brackets, gyroscopic eye-bolt connectors, and other various connection components, Logic/Path Planning Vision System

  8. FTIR analysis of surface functionalities on particulate matter produced by off-road diesel engines operating on diesel and biofuel.

    PubMed

    Popovicheva, Olga B; Kireeva, Elena D; Shonija, Natalia K; Vojtisek-Lom, Michal; Schwarz, Jaroslav

    2015-03-01

    Fourier transform infrared spectroscopy is applied as a powerful analytic technique for the evaluation of the chemical composition of combustion aerosols emitted by off-road engines fuelled by diesel and biofuels. Particles produced by burning diesel, heated rapeseed oil (RO), RO with ethylhexylnitrate, and heated palm oil were sampled from exhausts of representative in-use diesel engines. Multicomponent composition of diesel and biofuel particles reveal the chemistry related to a variety of functional groups containing carbon, hydrogen, oxygen, sulfur, and nitrogen. The most intensive functionalities of diesel particles are saturated C-C-H and unsaturated C=C-H aliphatic groups in alkanes and alkenes, aromatic C=C and C=C-H groups in polyaromatics, as well as sulfates and nitrated ions. The distinguished features of biofuel particles were carbonyl C=O groups in carboxylic acids, ketones, aldehydes, esters, and lactones. NO2, C-N and -NH groups in nitrocompounds and amines are found to dominate biofuel particles. Group identification is confirmed by complementary measurements of organic carbon (OC), elemental carbon, and water-soluble ion species. The relationship between infrared bands of polar oxygenated and non-polar aliphatic functionalities indicates the higher extent of the surface oxidation of biofuel particles. Findings provide functional markers of organic surface structure of off-road diesel emission, allowing for a better evaluation of relation between engine, fuel, operation condition, and particle composition, thus improving the quantification of environmental impacts of alternative energy source emissions. PMID:25318418

  9. 78 FR 58089 - California State Nonroad Engine Pollution Control Standards; Off-Road Compression Ignition...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-20

    ....\\4\\ \\2\\ 59 FR 36969 (July 20, 1994). \\3\\ See 62 FR 67733 (December 30, 1997). The applicable regulations are now found in 40 CFR part 1074, subpart B, Sec. 1074.105. \\4\\ See 59 FR 36969 (July 20, 1994...) on motor vehicles.'' \\6\\ See EPA's Final 209(e) rulemaking at 59 FR 36969, 36983 (July 20, 1994)....

  10. Evaluation of off-road terrain with static stereo and monoscopic displays

    NASA Technical Reports Server (NTRS)

    Yorchak, John P.; Hartley, Craig S.

    1990-01-01

    The National Aeronautics and Space Administration is currently funding research into the design of a Mars rover vehicle. This unmanned rover will be used to explore a number of scientific and geologic sites on the Martian surface. Since the rover can not be driven from Earth in real-time, due to lengthy communication time delays, a locomotion strategy that optimizes vehicle range and minimizes potential risk must be developed. In order to assess the degree of on-board artificial intelligence (AI) required for a rover to carry out its' mission, researchers conducted an experiment to define a no AI baseline. In the experiment 24 subjects, divided into stereo and monoscopic groups, were shown video snapshots of four terrain scenes. The subjects' task was to choose a suitable path for the vehicle through each of the four scenes. Paths were scored based on distance travelled and hazard avoidance. Study results are presented with respect to: (1) risk versus range; (2) stereo versus monocular video; (3) vehicle camera height; and (4) camera field-of-view.

  11. 75 FR 71730 - General Management Plan/Wilderness Study/Off-Road Vehicle Management Plan, Final Environmental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ...Final Environmental Impact Statement, Big Cypress National Preserve Addition, Florida...Management Plan (FEIS/GMP/WS/ORV Plan), Big Cypress National Preserve (Preserve) Addition...Statement for the GMP/WS/ORV Plan for the Big Cypress National Preserve Addition,...

  12. 75 FR 48721 - Draft Environmental Impact Statement on Nabesna Off-Road Vehicle Management Plan, Wrangell-St...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ... requested from Meg Jensen, Superintendent, Wrangell-St. Elias National Park and Preserve, P.O. Box 439...-delivered to Meg Jensen, Superintendent, Wrangell-St. Elias National Park and Preserve, P.O. Box 439,...

  13. Impact analysis of off-road-vehicle use on vegetation in the Grand Mere dune environment. [Lake Michigan

    NASA Technical Reports Server (NTRS)

    Schultink, G. (principal investigator)

    1977-01-01

    The author has identified the following significant results. A linear regression between percent nonvegetative land and the time variable was completed for the two sample areas. Sample area no. 1 showed an average vegetation loss of 1.901% per year, while the loss for sample area no. 2 amounted to 5.889% per year. Two basic reasons for the difference were assumed to play a role: the difference in access potential and the amount of already fragmented vegetation complexes in existence during the first year of the comparative analysis - 1970. Sample area no. 2 was located closer to potential access points and was more fragmented initially.

  14. 75 FR 48721 - Draft Environmental Impact Statement on Nabesna Off-Road Vehicle Management Plan, Wrangell-St...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ...are available at park headquarters, or may be requested from Meg Jensen, Superintendent, Wrangell-St. Elias National Park...Service or other mail delivery service or hand-delivered to Meg Jensen, Superintendent, Wrangell-St. Elias National...

  15. 77 FR 20843 - Record of Decision for the Nabesna Off-Road Vehicle Management Plan and Final Environmental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-06

    ...DEPARTMENT OF THE INTERIOR National Park Service [NPS-AKR-WRST-0112-9413...Environmental Impact Statement, Wrangell-St. Elias National Park and Preserve AGENCY: National Park Service, Interior. ACTION: Notice of...

  16. 76 FR 55840 - Cape Hatteras National Seashore Proposed Rule: Off-Road Vehicle Management-Reopening of Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-09

    ...for those who may have been affected by Hurricane Irene to submit comments. DATES: Comments...proposal closed on September 6, 2011. Hurricane Irene made landfall in the area of the...east coast into New England. Because hurricane damage may have prevented some...

  17. 76 FR 3653 - 2011 Meetings of the Big Cypress National Preserve Off-Road Vehicle (ORV) Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-20

    ...In accordance with the Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770, 5 U.S.C. App 1, 10), notice is hereby given of the meetings of the Big Cypress National Preserve ORV Advisory Committee for...

  18. A Laser Based Rut Detection and Following System for Autonomous Ground Vehicles

    E-print Network

    Collins, Emmanuel

    A Laser Based Rut Detection and Following System for Autonomous Ground Vehicles Camilo Ordonez and following system is proposed so that autonomous ground vehicles can benefit from the application of this off Tallahassee, Florida 32310 Abstract An important off road driving rule is to keep the vehicle wheels

  19. A BIO-DIESEL BAJA VEHICLE AND STUDENT COMPETITION

    EPA Science Inventory

    The SAE Mini Baja® competition is an extremely popular design competition for students in engineering programs around the world. The competition focuses on the design of an off-road vehicle for performance and cost-of-production. The objective of the proposed effort is to ...

  20. The Pimlico Chemistry Trail.

    ERIC Educational Resources Information Center

    Borrows, Peter

    1984-01-01

    Describes a chemistry "trail" (similar to a nature trail) which focuses on chemical phenomena in the environment. The trail includes 20 stops in and around a local school. Types of phenomena examined include building materials, air pollution, corrosion of metals, swimming pools, and others. Additional activities are also suggested. (DH)

  1. 25 CFR 170.137 - What types of activities can a recreation, tourism, and trails program include?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...activities can a recreation, tourism, and trails program include...perform under a recreation, tourism, and trails program: (1) Transportation planning for tourism and recreation travel; ...vehicle parking areas; (3) Development of tourist information...

  2. 25 CFR 170.137 - What types of activities can a recreation, tourism, and trails program include?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...activities can a recreation, tourism, and trails program include...perform under a recreation, tourism, and trails program: (1) Transportation planning for tourism and recreation travel; ...vehicle parking areas; (3) Development of tourist information...

  3. Military vehicle trafficking impacts vegetation and soil bulk density at Fort Benning, Georgia

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Potential increases in wind erosion that might be brought about by military vehicles travelling off-road during training are of concern to the United States military. Field studies were conducted in the summer of 2012 at Fort Benning, Georgia. The objective of the experiment was to assess the traffi...

  4. Military vehicle trafficking impacts on vegetation and soil bulk density at Fort Benning, Georgia

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Potential increases in wind erosion that might be brought about by military vehicles travelling on off-road sites during training are of concern to the Military establishment. Field studies were conducted in the summer of 2012 at Fort Benning, Georgia. The objective of the experiment was to assess t...

  5. Micro-unmanned aerodynamic vehicle

    SciTech Connect

    Reuel, Nigel; Lionberger, Troy A.; Galambos, Paul C.; Okandan, Murat; Baker, Michael S.

    2008-03-11

    A MEMS-based micro-unmanned vehicle includes at least a pair of wings having leading wing beams and trailing wing beams, at least two actuators, a leading actuator beam coupled to the leading wing beams, a trailing actuator beam coupled to the trailing wing beams, a vehicle body having a plurality of fulcrums pivotally securing the leading wing beams, the trailing wing beams, the leading actuator beam and the trailing actuator beam and having at least one anisotropically etched recess to accommodate a lever-fulcrum motion of the coupled beams, and a power source.

  6. DIRBE Comet Trails

    NASA Astrophysics Data System (ADS)

    Arendt, Richard G.

    2014-12-01

    Re-examination of the Cosmic Background Explorer Diffuse Infrared Background Experiment (DIRBE) data reveals the thermal emission of several comet dust trails. The dust trails of 1P/Halley, 169P/NEAT, and 3200 Phaethon have not been previously reported. The known trails of 2P/Encke and 73P/Schwassmann-Wachmann 3 are also seen. The dust trails have 12 and 25 ?m surface brightnesses of \\lt 0.1 and \\lt 0.15 MJy sr-1, respectively, which is \\lt 1% of the zodiacal light intensity. The trails are very difficult to see in any single daily image of the sky, but are evident as rapidly moving linear features in movies of the DIRBE data. Some trails are clearest when crossing through the orbital plane of the parent comet, but others are best seen at high ecliptic latitudes as the Earth passes over or under the dust trail. All these comets have known associations with meteor showers. This re-examination also reveals 1 additional comet and 13 additional asteroids that had not previously been recognized in the DIRBE data.

  7. DIRBE Comet Trails

    NASA Technical Reports Server (NTRS)

    Arendt, Richard G.

    2015-01-01

    Re-examination of the COBE DIRBE data reveals the thermal emission of several comet dust trails.The dust trails of 1P/Halley, 169P/NEAT, and 3200 Phaethon have not been previously reported.The known trails of 2P/Encke, and 73P/Schwassmann-Wachmann 3 are also seen. The dust trails have 12 and 25 microns surface brightnesses of <0.1 and <0.15 MJy/sr, respectively, which is <1% of the zodiacal light intensity. The trails are very difficult to see in any single daily image of the sky, but are evident as rapidly moving linear features in movies of the DIRBE data. Some trails are clearest when crossing through the orbital plane of the parent comet, but others are best seen at high ecliptic latitudes as the Earth passes over or under the dust trail. All these comets have known associations with meteor showers. This re-examination also reveals one additional comet and 13 additional asteroids that had not previously been recognized in the DIRBE data.

  8. DRBE comet trails

    SciTech Connect

    Arendt, Richard G.

    2014-12-01

    Re-examination of the Cosmic Background Explorer Diffuse Infrared Background Experiment (DIRBE) data reveals the thermal emission of several comet dust trails. The dust trails of 1P/Halley, 169P/NEAT, and 3200 Phaethon have not been previously reported. The known trails of 2P/Encke and 73P/Schwassmann–Wachmann 3 are also seen. The dust trails have 12 and 25 ?m surface brightnesses of <0.1 and <0.15 MJy sr{sup ?1}, respectively, which is <1% of the zodiacal light intensity. The trails are very difficult to see in any single daily image of the sky, but are evident as rapidly moving linear features in movies of the DIRBE data. Some trails are clearest when crossing through the orbital plane of the parent comet, but others are best seen at high ecliptic latitudes as the Earth passes over or under the dust trail. All these comets have known associations with meteor showers. This re-examination also reveals 1 additional comet and 13 additional asteroids that had not previously been recognized in the DIRBE data.

  9. TREE TRAILS Career Cards

    E-print Network

    Specialist Wildland Firefighter Wildlife Biologist Writer #12;Module 4 TREE TRAILS Instructional Procedures that uses computers to create and maintain data and maps Wildland Firefighter a person puts out a fire

  10. Propane Vehicle Demonstration Grant Program

    SciTech Connect

    Jack Mallinger

    2004-08-27

    Project Description: Propane Vehicle Demonstration Grants The Propane Vehicle Demonstration Grants was established to demonstrate the benefits of new propane equipment. The US Department of Energy, the Propane Education & Research Council (PERC) and the Propane Vehicle Council (PVC) partnered in this program. The project impacted ten different states, 179 vehicles, and 15 new propane fueling facilities. Based on estimates provided, this project generated a minimum of 1,441,000 new gallons of propane sold for the vehicle market annually. Additionally, two new off-road engines were brought to the market. Projects originally funded under this project were the City of Portland, Colorado, Kansas City, Impco Technologies, Jasper Engines, Maricopa County, New Jersey State, Port of Houston, Salt Lake City Newspaper, Suburban Propane, Mutual Liquid Propane and Ted Johnson.

  11. A Dusty Trail 

    E-print Network

    Unknown

    2011-09-05

    Metropolitan Area Map 1-13 Section 2: Planning Factors Section 3: Transit Element Section 4: Road and Trail Element Appendix A: Historical Growth Trends Links to Additional Reference Materials Abilene Comprehensive Plan http... of the transportation system for motorized and nonmotorized users Safety of the users of the transportation system is a primary consideration in the development of plans and projects. Virtually all TIP and road and trail improvement projects include safety...

  12. Cooking with Trail Mix 

    E-print Network

    Anding, Jenna

    2008-12-09

    2 eggs ? cup sugar ? teaspoon vanilla 1? cups trail mix How to make it 1. Wash your hands; make sure your cooking area is clean. 2... stream_source_info pdf_1440.pdf.txt stream_content_type text/plain stream_size 3174 Content-Encoding ISO-8859-1 stream_name pdf_1440.pdf.txt Content-Type text/plain; charset=ISO-8859-1 E-78 12/08 Cooking with Trail Mix...

  13. Certification trails for data structures

    NASA Technical Reports Server (NTRS)

    Sullivan, Gregory F.; Masson, Gerald M.

    1993-01-01

    Certification trails are a recently introduced and promising approach to fault detection and fault tolerance. The applicability of the certification trail technique is significantly generalized. Previously, certification trails had to be customized to each algorithm application; trails appropriate to wide classes of algorithms were developed. These certification trails are based on common data-structure operations such as those carried out using these sets of operations such as those carried out using balanced binary trees and heaps. Any algorithms using these sets of operations can therefore employ the certification trail method to achieve software fault tolerance. To exemplify the scope of the generalization of the certification trail technique provided, constructions of trails for abstract data types such as priority queues and union-find structures are given. These trails are applicable to any data-structure implementation of the abstract data type. It is also shown that these ideals lead naturally to monitors for data-structure operations.

  14. Potential ozone impacts of excess NO2 emissions from diesel particulate filters for on- and off-road diesel engines.

    PubMed

    Bar-llan, Amnon; Johnson, Jeremiah R; Denbleyker, Allison; Chan, Lit-Mian; Yarwood, Gregory; Hitchcock, David; Pinto, Joseph P

    2010-08-01

    This study considers potential impacts of increased use of diesel oxidation catalysts (DOCs) and catalyzed diesel particulate filters (DPFs) on ozone formation in the Dallas/ Fort Worth (DFW) area. There is concern that excess nitrogen dioxide (NO2) emissions from vehicles equipped with these devices could increase ambient ozone levels. The approach involved developing two scenarios for use of these devices, quantifying excess NO2 emissions in each scenario, and using a photochemical model to estimate the resulting ozone changes. In the "maximum penetration" scenario, DOC/DPF devices in a 2009 fleet of heavy-duty on-road trucks, school buses, and construction equipment were significantly increased by accelerating turnover of these vehicles and equipment to models that would require DOCs/DPFs. In the "realistic" scenario, current fractional usage of these devices was assessed for 2009. For both scenarios, excess NO2 emissions from DOCs/DPFs were estimated using U.S. Environmental Protection Agency's MOBILE6 and NONROAD emissions inventory modeling tools. The emissions analyses were used to adjust the DFW photochemical modeling emissions inventories and the Comprehensive Air Quality Model with extensions air quality model was rerun for the DFW area to determine the impact of these two scenarios on ozone formation. The maximum penetration scenario, which showed an overall reduction in oxides of nitrogen (NO(x)) because of the accelerated turnover of equipment to cleaner models, resulted in a net decrease in daily maximum 8-hr ozone of 4-5 parts per billion (ppb) despite the increase in NO2 emissions. The realistic scenario resulted in a small increase in daily maximum 8-hr ozone of less than 1 ppb for the DFW area. It was concluded that the excess NO2 emissions from DOC/DPF devices result in very small ozone impacts, particularly for the realistic scenario, in the DFW area. There are noticeable decreases in ozone for the maximum penetration scenario because NO(x) reductions associated with DOC/DPFs (i.e., accelerated fleet turnover) exert more influence than excess NO2. PMID:20842938

  15. The confining trailing string

    E-print Network

    E. Kiritsis; L. Mazzanti; F. Nitti

    2014-12-03

    We extend the holographic trailing string picture of a heavy quark to the case of a bulk geometry dual to a confining gauge theory. We compute the classical trailing confining string solution for a static as well as a uniformly moving quark. The trailing string is infinitely extended and approaches a confining horizon, situated at a critical value of the radial coordinate, along one of the space-time directions, breaking boundary rotational invariance. We compute the equations for the fluctuations around the classical solutions, which are used to obtain boundary force correlators controlling the Langevin dynamics of the quark. The imaginary part of the correlators has a non-trivial low-frequency limit, which gives rise to a viscous friction coefficient induced by the confining vacuum. The vacuum correlators are used to define finite-temperature dressed Langevin correlators with an appropriate high-frequency behavior.

  16. Trailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer Cells

    PubMed Central

    Trivedi, Rachana; Mishra, Durga Prasad

    2015-01-01

    Resistance to chemotherapeutic drugs is the major hindrance in the successful cancer therapy. The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the tumor necrosis factor (TNF) family of ligands, which initiates apoptosis in cancer cells through interaction with the death receptors DR4 and DR5. TRAIL is perceived as an attractive chemotherapeutic agent as it specifically targets cancer cells while sparing the normal cells. However, TRAIL therapy has a major limitation as a large number of the cancer develop resistance toward TRAIL and escape from the destruction by the immune system. Therefore, elucidation of the molecular targets and signaling pathways responsible for TRAIL resistance is imperative for devising effective therapeutic strategies for TRAIL resistant cancers. Although, various molecular targets leading to TRAIL resistance are well-studied, recent studies have implicated that the contribution of some key cellular processes toward TRAIL resistance need to be fully elucidated. These processes primarily include aberrant protein synthesis, protein misfolding, ubiquitin regulated death receptor expression, metabolic pathways, epigenetic deregulation, and metastasis. Novel synthetic/natural compounds that could inhibit these defective cellular processes may restore the TRAIL sensitivity and combination therapies with such compounds may resensitize TRAIL resistant cancer cells toward TRAIL-induced apoptosis. In this review, we have summarized the key cellular processes associated with TRAIL resistance and their status as therapeutic targets for novel TRAIL-sensitizing agents. PMID:25883904

  17. Comprehensive Trail Making Test

    ERIC Educational Resources Information Center

    Gray, Rebecca

    2006-01-01

    The Comprehensive Trail Making Test (CTMT) is designed to be used in neuropsychological assessment for the purposes of detecting effects of brain defects and deficits and in tracking progress in rehabilitation. More specific purposes include the detection of frontal lobe deficits, problems with psychomotor speed, visual search and sequencing,…

  18. Queen's Garden Trail

    USGS Multimedia Gallery

    Views along the Queen's Garden Trail in Bryce Canyon National Park. Bryce Canyon is a unique sandstone formation in southern Utah. It is home to a large number of hoodoos, which are oddly shaped pillars of rock that formed due to different erosion rates for the dolomite that caps them and the sands...

  19. 36 CFR 212.51 - Designation of roads, trails, and areas.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Designation of roads, trails, and areas. 212.51 Section 212.51 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE TRAVEL MANAGEMENT Designation of Roads, Trails, and Areas for Motor Vehicle Use §...

  20. 36 CFR 212.51 - Designation of roads, trails, and areas.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Designation of roads, trails, and areas. 212.51 Section 212.51 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE TRAVEL MANAGEMENT Designation of Roads, Trails, and Areas for Motor Vehicle Use §...

  1. 36 CFR 212.51 - Designation of roads, trails, and areas.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Designation of roads, trails, and areas. 212.51 Section 212.51 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE TRAVEL MANAGEMENT Designation of Roads, Trails, and Areas for Motor Vehicle Use §...

  2. Illusion or guide to strategy: The emission inventory - shift in relative proportions of stationary (point), mobile (on-road), area (consumer product), and off-road sources as the primary category approach attainment

    SciTech Connect

    Billheimer, J.S.; Harper, J.; Laird, E.

    1996-12-31

    This assumes not only stationary [point] sources, but all corroborative sources: Area [Consumer Products], and Mobile on-road and Mobile Off-road maintain proportional rates of reduction. Trend charts indicate that whereas traditional Stationary Sources [essentially `Industry`] and also Mobile on-road are maintaining a steady emission reduction path, they are reasonably expected to diminish below the once secondary sources of Area and Off-road operations, which are just getting started on effective emission reduction campaigns. The greater difficulty in establishing effective emission reduction strategies for such `indirect` sources is noted, and the demise of the infamous trip reduction car pooling regulation [SCAQMD Reg. XVI] and the Federal Implementation Plan [FIP] are taken as indicators that the Public still looks to `Industry` as the primary source of air pollution, and is ill-prepared to take personal responsibility and individual sacrifice necessary to obtain significant emission reductions in Area [Consumer Product] and off-road Equipment [Recreational, Construction, Agricultural] to parallel Stationary [Point Source] and Mobile [On-road] campaigns for air quality attainment now in progress. The `hard facts` of emission inventory make this starkly evident, especially in case of PM-10, where `entrained road dust`, a Mobility, if not a Mobile, source, looms as the largest single category of all PM-10 campaigns.

  3. Bypassing the need for pre-sensitization of cancer cells for anticancer TRAIL therapy with secretion of novel cell penetrable form of Smac from hA-MSCs as cellular delivery vehicle.

    PubMed

    Khorashadizadeh, Mohsen; Soleimani, Masoud; Khanahmad, Hossein; Fallah, Ali; Naderi, Mahmood; Khorramizadeh, Mohammadreza

    2015-06-01

    TNF-related apoptosis inducing ligand (TRAIL) is a novel anticancer agent with selective apoptosis-inducing activity on cancer cells. However, many malignant tumors still remain unresponsive. Although cells can bypass apoptosis by different functions, the defect in the blocking role of second mitochondria-derived activator of caspase (Smac) on X-linked inhibitor of apoptosis protein (XIAP) is known to be an important hub for immortal characteristic of malignant cells. Actually, XIAP is known as an apoptosis inhibitor. To date, the sensitization of cancerous cells to TRAIL was successfully performed with different protocols, mainly through blocking XIAP with Smac administration. However, all these sensitization methodologies need to be performed prior to TRAIL administration on cancerous cells which in turn limit their practical application in clinics. Therefore, we hypothesized that concurrent expression of Smac and TRAIL on human adipose-derived mesenchymal stem cells (hA-MSC-ST) could both sensitize and destroy cancerous cells. To this aim, we generated hA-MSC-ST, secreting a novel cell penetrable form of Smac and a trimeric form of TRAIL. Indeed, the cell penetrable form of Smac obviates the need for any pretreatment of cancerous cells. Our data depicted that individual overexpression of TRAIL or Smac in different breast cancer cell types induced limited or no apoptosis, respectively. Conversely, their concomitant overexpression markedly increased cell death even for a resistant type of breast cancer cells, MCF-7. Notably, we observed no cytotoxicity of our methodology on normal cells. In summary, this is the first demonstration that a dual approach using simultaneous overexpression of a cell penetrable form of Smac and TRAIL sensitize and promote apoptotic process even in resistant breast cancer cells. PMID:25586349

  4. Tracking Online Trails

    NASA Astrophysics Data System (ADS)

    Qi, Man; Edgar-Nevill, Denis; Wang, Yongquan; Xu, Rongsheng

    Traceability is a key to the investigation of the internet criminal and a cornerstone of internet research. It is impossible to prevent all internet misuse but may be possible to identify and trace the users, and then take appropriate action. This paper presents the value of traceability within the email/-newsposting utilities, the technologies being using to hide identities, the difficulties in locating the traceable data and the challenges in tracking online trails.

  5. Advanced Vehicle Testing and Evaluation

    SciTech Connect

    Garetson, Thomas

    2013-03-31

    The objective of the United States (U.S.) Department of Energy?s (DOEs) Advanced Vehicle Testing and Evaluation (AVTE) project was to provide test and evaluation services for advanced technology vehicles, to establish a performance baseline, to determine vehicle reliability, and to evaluate vehicle operating costs in fleet operations. Vehicles tested include light and medium-duty vehicles in conventional, hybrid, and all-electric configurations using conventional and alternative fuels, including hydrogen in internal combustion engines. Vehicles were tested on closed tracks and chassis dynamometers, as well as operated on public roads, in fleet operations, and over prescribed routes. All testing was controlled by procedures developed specifically to support such testing. Testing and evaluations were conducted in the following phases: ? Development of test procedures, which established testing procedures; ? Baseline performance testing, which established a performance baseline; ? Accelerated reliability testing, which determined vehicle reliability; ? Fleet testing, used to evaluate vehicle economics in fleet operation, and ? End of test performance evaluation. Test results are reported by two means and posted by Idaho National Laboratory (INL) to their website: quarterly progress reports, used to document work in progress; and final test reports. This final report documents work conducted for the entirety of the contract by the Clarity Group, Inc., doing business as ECOtality North America (ECOtality). The contract was performed from 1 October 2005 through 31 March 2013. There were 113 light-duty on-road (95), off-road (3) and low speed (15) vehicles tested.

  6. The influence of use-related, environmental, and managerial factors on soil loss from recreational trails

    USGS Publications Warehouse

    Olive, N.D.; Marion, J.L.

    2009-01-01

    Recreational uses of unsurfaced trails inevitably result in their degradation, with the type and extent of resource impact influenced by factors such as soil texture, topography, climate, trail design and maintenance, and type and amount of use. Of particular concern, the loss of soil through erosion is generally considered a significant and irreversible form of trail impact. This research investigated the influence of several use-related, environmental, and managerial factors on soil loss on recreational trails and roads at Big South Fork National River and Recreation Area, a unit of the U.S. National Park Service. Regression modeling revealed that trail position, trail slope alignment angle, grade, water drainage, and type of use are significant determinants of soil loss. The introduction of individual and groups of variables into a series of regression models provides improved understanding and insights regarding the relative influence of these variables, informing the selection of more effective trail management actions. Study results suggest that trail erosion can be minimized by avoiding ?fall-line? alignments, steep grades, and valley-bottom alignments near streams, installing and maintaining adequate densities of tread drainage features, applying gravel to harden treads, and reducing horse and all-terrain vehicle use or restricting them to more resistant routes. This research also sought to develop a more efficient Variable Cross-Sectional Area method for assessing soil loss on trails. This method permitted incorporation of CSA measures in a representative sampling scheme applied to a large (24%) sample of the park's 526 km trail system. The variety of soil loss measures derived from the Variable CSA method, including extrapolated trail-wide soil loss estimates, permit an objective quantification of soil erosion on recreational trails and roads. Such data support relational analyses to increase understanding of trail degradation, and long-term monitoring of the natural and recreational integrity of the trail system infrastructure.

  7. 75 FR 37462 - Official Trail Marker for the Captain John Smith Chesapeake National Historic Trail

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ...Service Official Trail Marker for the Captain John Smith Chesapeake National Historic Trail...official trail marker insignias of the Captain John Smith Chesapeake National Historic Trail...The primary author of this document is John Maounis, Superintendent, Captain...

  8. Analyzing trails in complex networks

    NASA Astrophysics Data System (ADS)

    da Fontoura Costa, Luciano; Rodrigues, Francisco A.; Travieso, Gonzalo

    2007-10-01

    Even more interesting than the intricate organization of complex networks is the dynamical behavior of systems underlain by such structures. Among the many types of dynamics, one particularly interesting category involves the evolution of trails left by moving agents progressing through random walks and dilating processes in a complex network. The emergence of trails is present in many dynamical process, such as pedestrian traffic, information flow, and metabolic pathways. Important problems related to trails include the reconstruction of the trail and the identification of its source, when complete knowledge of the trail is missing. In addition, the following of trails in multiagent systems represents a particularly interesting situation related to pedestrian dynamics and swarming intelligence. The present work addresses these three issues while taking into account permanent and transient marks left in the visited nodes. Different topologies are considered for trail reconstruction and trail source identification, including four complex network models and four real networks, namely, the Internet, the U.S. airlines network, an email network, and the scientific collaboration network of complex network researchers. Our results show that the topology of the network influences trail reconstruction, source identification, and agent dynamics.

  9. Real-Time and High-Fidelity Simulation Environment for Autonomous Ground Vehicle Dynamics

    NASA Technical Reports Server (NTRS)

    Cameron, Jonathan; Myint, Steven; Kuo, Calvin; Jain, Abhi; Grip, Havard; Jayakumar, Paramsothy; Overholt, Jim

    2013-01-01

    This paper reports on a collaborative project between U.S. Army TARDEC and Jet Propulsion Laboratory (JPL) to develop a unmanned ground vehicle (UGV) simulation model using the ROAMS vehicle modeling framework. Besides modeling the physical suspension of the vehicle, the sensing and navigation of the HMMWV vehicle are simulated. Using models of urban and off-road environments, the HMMWV simulation was tested in several ways, including navigation in an urban environment with obstacle avoidance and the performance of a lane change maneuver.

  10. TRAIL combinations: The new ‘trail’ for cancer therapy (Review)

    PubMed Central

    REFAAT, ALAA; ABD-RABOU, AHMED; REDA, ASMAA

    2014-01-01

    Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) therapy is anticipated to be one of the most effective cancer treatments. However, resistance to TRAIL therapy remains a challenge facing the development of anticancer strategies. To circumvent this problem, TRAIL combinations have been experimented with for over ten years to induce synergism or sensitize resistant cancer cells. By analyzing the signaling pathways triggered by these combinations, this review has defined a set of core targets for novel combinatorial treatments. The review suggests specific pathways to be targeted together with TRAIL for more efficient treatment, including cellular FLICE inhibitory protein and its downstream survival factors, the Bcl-2 family and other prominent targets. The suggested pathways provide new avenues for more effective TRAIL-based cancer therapy. PMID:24765133

  11. SCHROTH INTERPRETIVE TRAIL DEMONSTRATION PRAIRIE

    E-print Network

    Chen, Deming

    SCHROTH INTERPRETIVE TRAIL MUSIC BARN DEMONSTRATION PRAIRIE FORMER SITE OF THE LOST GARDEN PIONEER and upland forests, a meadow and a 30-acre demonstration prairie » 14 miles of interpretive hiking trails Institute of Architects'List of 150 Great Places in Illinois. #12;FU DOG GARDEN (SCULPTURES) HOUSE

  12. 36 CFR 331.12 - Vehicles.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... vehicles, including, but not limited to, automobiles, trucks, motorcycles, minibikes, trail bikes... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Vehicles. 331.12 Section 331..., KENTUCKY AND INDIANA § 331.12 Vehicles. (a) The use of a vehicle off roadways is prohibited except as...

  13. Sensing, Control, and System Integration for Autonomous Vehicles: A Series of Challenges

    NASA Astrophysics Data System (ADS)

    Özgüner, Ümit; Redmill, Keith

    One of the important examples of mechatronic systems can be found in autonomous ground vehicles. Autonomous ground vehicles provide a series of challenges in sensing, control and system integration. In this paper we consider off-road autonomous vehicles, automated highway systems and urban autonomous driving and indicate the unifying aspects. We specifically consider our own experience during the last twelve years in various demonstrations and challenges in attempting to identify unifying themes. Such unifying themes can be observed in basic hierarchies, hybrid system control approaches and sensor fusion techniques.

  14. 17 CFR 37.205 - Audit trail.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false Audit trail. 37.205 Section 37... Compliance With Rules § 37.205 Audit trail. A swap execution facility shall establish procedures to capture...) Audit trail required. A swap execution facility shall capture and retain all audit trail data...

  15. Motion resistance of wheeled vehicles in snow

    NASA Astrophysics Data System (ADS)

    Richmond, Paul W.

    1995-03-01

    Before vehicle mobility in snow can be reliably predicted, a complete understanding of motion resistance in snow is required. This report examines several aspects of wheeled vehicle motion resistance using results obtained with the CRREL instrumented vehicle. Resistances of leading and trailing tires are examined. Limited data are presented for undercarriage drag, and third and fourth wheel passes in the same rut are initially analyzed, as is how snow deforms around a wheel. For the CRREL instrumented vehicle, a trailing tire has a resistance coefficient of about 0.017 for snow depths less than about 22cm. For deeper snow, the disruption of the snowpack caused by a preceding wheel causes snow to fall into the rut, resulting in higher trailing tire coefficients. For larger vehicles, which in some cases have trailing tires carrying larger loads than preceding tires, the trailing tire coefficients are on the order of 0.048 and 0.025 for second and third trailing wheels respectively. Since there are no trailing tire data available for these larger vehicles, these values are based on nonlinear regression analysis, which includes a prediction of the leading tire resistance. The results and observations of this study are applied in a reanalysis of the towed resistance data obtained during the U.S. Army's Wheels vs. Tracks study. An improved algorithm is presented for predicting wheeled vehicle motion resistance caused by snow.

  16. Experiences in teleoperation of land vehicles

    SciTech Connect

    McGovern, D.E.

    1987-01-01

    Teleoperation of land vehicles allows the removal of the operator from the vehicle to a remote location. This can greatly increase operator safety and comfort in applications such as security patrol or military combat. The cost includes system complexity and reduced system performance. All feedback on vehicle performance and on environmental conditions must pass through sensors, a communications channel, and displays. In particular, this requires vision to be transmitted by closed circuit television (CCTV), with a consequent degradation of information content. Vehicular teleoperation, as a result, places severe demands on the operator. Experimentation studying the effects of vision-system characteristics on off-road, remote driving has been performed for conditions of fixed camera versus steering coupled camera and color versus black and white video display. Additionally, much experience has been gained through system demonstrations and hardware development trials. This paper discusses the preliminary experimental findings and the results of the accumulated operational experience.

  17. Trail Pheromone Disruption of Argentine Ant Trail Formation and Foraging

    USGS Publications Warehouse

    Suckling, D.M.; Peck, R.W.; Stringer, L.D.; Snook, K.; Banko, P.C.

    2010-01-01

    Trail pheromone disruption of invasive ants is a novel tactic that builds on the development of pheromone-based pest management in other insects. Argentine ant trail pheromone, (Z)-9-hexadecenal, was formulated as a micro-encapsulated sprayable particle and applied against Argentine ant populations in 400 m2 field plots in Hawai'i Volcanoes National Park. A widely dispersed point source strategy for trail pheromone disruption was used. Traffic rates of ants in bioassays of treated filter paper, protected from rainfall and sunlight, indicated the presence of behaviorally significant quantities of pheromone being released from the formulation for up to 59 days. The proportion of plots, under trade wind conditions (2-3 m s-1), with visible trails was reduced for up to 14 days following treatment, and the number of foraging ants at randomly placed tuna-bait cards was similarly reduced. The success of these trail pheromone disruption trials in a natural ecosystem highlights the potential of this method for control of invasive ant species in this and other environments. ?? Springer Science+Business Media, LLC 2010.

  18. HUBBLE: ON THE ASTEROID TRAIL

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Astronomers Karl Stapelfeldt and Robin Evans have tracked down about 100 small asteroids by hunting through more than 28,000 archival images taken by the Hubble Space Telescope's Wide Field and Planetary Camera 2. Here is a sample of what they have found: four archival images that show the curved trails left by asteroids. [Top left]: Hubble captured a bright asteroid, with a visual magnitude of 18.7, roaming in the constellation Centaurus. Background stars are shown in white, while the asteroid trail is depicted in blue at top center. The trail has a length of 19 arc seconds. This asteroid has a diameter of one and one-quarter miles (2 kilometers), and was located 87 million miles from Earth and 156 million miles from the sun. Numerous orange and blue specks in this image and the following two images were created by cosmic rays, energetic subatomic particles that struck the camera's detector. [Top right]: Here is an asteroid with a visual magnitude of 21.8 passing a galaxy in the constellation Leo. The trail is seen in two consecutive exposures, the first shown in blue and the second in red. This asteroid has a diameter of half a mile (0.8 kilometers), and was located 188 million miles from Earth and 233 million miles from the sun. [Lower left]: This asteroid in the constellation Taurus has a visual magnitude of 23, and is one of the faintest seen so far in the Hubble archive. It moves from upper right to lower left in two consecutive exposures; the first trail is shown in blue and the second in red. Because of the asteroid's relatively straight trail, astronomers could not accurately determine its distance. The estimated diameter is half a mile (0.8 kilometers) at an Earth distance of 205 million miles and a sun distance of 298 million miles. [Lower right]: This is a broken asteroid trail crossing the outer regions of galaxy NGC 4548 in Coma Berenices. Five trail segments (shown in white) were extracted from individual exposures and added to a cleaned color image of the galaxy. The asteroid enters the image at top center and moves down toward the lower left. Large gaps in the trail occur because the telescope is orbiting the Earth and cannot continuously observe the galaxy. This asteroid has a visual magnitude of 20.8, a diameter of one mile (1.6 kilometers), and was seen at a distance of 254 million miles from Earth and 292 million miles from the sun. Credit: R. Evans and K. Stapelfeldt (Jet Propulsion Laboratory) and NASA

  19. Base passive porosity for vehicle drag reduction

    NASA Technical Reports Server (NTRS)

    Bauer, Steven X. S. (Inventor); Wood, Richard M. (Inventor)

    2003-01-01

    A device for controlling drag on a ground vehicle. The device consists of a porous skin or skins mounted on the trailing surface and/or aft portions of the ground vehicle. The porous skin is separated from the vehicle surface by a distance of at least the thickness of the porous skin. Alternately, the trailing surface, sides, and/or top surfaces of the ground vehicle may be porous. The device minimizes the strength of the separation in the base and wake regions of the ground vehicle, thus reducing drag.

  20. Base Passive Porosity for Vehicle Drag Reduction

    NASA Technical Reports Server (NTRS)

    Bauer, Steven X. S. (Inventor); Wood, Richard M. (Inventor)

    2003-01-01

    A device for controlling drag on a ground vehicle. The device consists of a porous skin or skins mounted on the trailing surface and/or aft portions of the ground vehicle. The porous skin is separated from the vehicle surface by a distance of at least the thickness of the porous skin. Alternately, the trailing surface, sides, and/or top surfaces of the ground vehicle may be porous. The device minimizes the strength of the separation in the base and wake regions of the ground vehicle, thus reducing drag.

  1. Routing Vehicles with Ants

    NASA Astrophysics Data System (ADS)

    Tan, Wen Fang; Lee, Lai Soon; Majid, Zanariah Abdul; Seow, Hsin Vonn

    Routing vehicles involve the design of an optimal set of routes for a fleet of vehicles to serve a number of customers with known demands. This research develops an Ant Colony Optimization for the vehicle routing with one central depot and identical vehicles. The procedure simulates the behavior of real ants that always find the shortest path between their nest and a food source through a form of communication, pheromone trail. Finally, preliminary results on the learning of the algorithm testing on benchmark data set will be presented in this paper.

  2. Fuel cell power system for utility vehicle

    SciTech Connect

    Graham, M.; Barbir, F.; Marken, F.; Nadal, M.

    1996-12-31

    Based on the experience of designing and building the Green Car, a fuel cell/battery hybrid vehicle, and Genesis, a hydrogen/oxygen fuel cell powered transporter, Energy Partners has developed a fuel cell power system for propulsion of an off-road utility vehicle. A 10 kW hydrogen/air fuel cell stack has been developed as a prototype for future mass production. The main features of this stack are discussed in this paper. Design considerations and selection criteria for the main components of the vehicular fuel cell system, such as traction motor, air compressor and compressor motor, hydrogen storage and delivery, water and heat management, power conditioning, and control and monitoring subsystem are discussed in detail.

  3. 75 FR 37463 - Official Trail Marker for the Star-Spangled Banner National Historic Trail

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ... National Park Service Official Trail Marker for the Star-Spangled Banner National Historic Trail AGENCY.... SUMMARY: This notice issues the official trail marker insignia of the Star-Spangled Banner National..., Superintendent, Star-Spangled Banner National Historic Trail. The insignia depicted below is prescribed as...

  4. 75 FR 37463 - Official Trail Marker for the Star-Spangled Banner National Historic Trail

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ...Park Service Official Trail Marker for the Star-Spangled Banner National Historic Trail...the official trail marker insignia of the Star-Spangled Banner National Historic Trail...document is John Maounis, Superintendent, Star-Spangled Banner National Historic...

  5. Plasma instabilities in meteor trails: Linear theory

    E-print Network

    Oppenheim, Meers

    Plasma instabilities in meteor trails: Linear theory Meers M. Oppenheim, Lars P. Dyrud, and Licia, such as those found at Jicamarca, Arecibo, and Kwajalein. This paper presents a theory of meteor trail electric field, the resulting electron drifts, and the linear plasma instabilities of meteor trails

  6. Bryce Canyon's Navajo Loop Trail

    USGS Multimedia Gallery

    Views along the Navajo Loop Trail in Bryce Canyon National Park. Bryce Canyon is a unique sandstone formation in southern Utah. It is home to a large number of hoodoos, which are oddly shaped pillars of rock that formed due to different erosion rates for the dolomite that caps them and the sandston...

  7. Carving a New Assessment Trail

    ERIC Educational Resources Information Center

    Morriston, Terry

    2007-01-01

    TRAILS (Tool for Real-Time Assessment of Information Literacy Skills), is a free online test of student information-handling skills. It was formulated by the Institute for Library and Information Literacy Education and Kent State University Libraries. Based on the Ohio Academic Content Standards and the philosophy of Information Power, it assesses…

  8. The Healthy Trail Food Book.

    ERIC Educational Resources Information Center

    Miller, Dorcas S.

    An 800-mile canoe trip down a Canadian river provided the testing ground for the tenets of this trail food book. On the seven week expedition two pounds of food per person per day at a daily cost of $1.70 were carried. The only perishables were cheese, margarine, and onions. Recipes and menu ideas from that expedition are provided along with…

  9. A Mathematics and Science Trail

    ERIC Educational Resources Information Center

    Smith, Kathy Horak; Fuentes, Sarah Quebec

    2012-01-01

    In an attempt to engage primary-school students in a hands-on, real-world problem-solving context, a large urban district, a mathematics and science institute housed in a college of education, and a corporate sponsor in the southwest United States, joined forces to create a mathematics and science trail for fourth- and fifth-grade students. A…

  10. Electronic Escape Trails for Firefighters

    NASA Technical Reports Server (NTRS)

    Jorgensen, Charles; Schipper, John; Betts, Bradley

    2008-01-01

    A proposed wireless-communication and data-processing system would exploit recent advances in radio-frequency identification devices (RFIDs) and software to establish information lifelines between firefighters in a burning building and a fire chief at a control station near but outside the building. The system would enable identification of trails that firefighters and others could follow to escape from the building, including identification of new trails should previously established trails become blocked. The system would include a transceiver unit and a computer at the control station, portable transceiver units carried by the firefighters in the building, and RFID tags that the firefighters would place at multiple locations as they move into and through the building (see figure). Each RFID tag, having a size of the order of a few centimeters, would include at least standard RFID circuitry and possibly sensors for measuring such other relevant environmental parameters as temperature, levels of light and sound, concentration of oxygen, concentrations of hazardous chemicals in smoke, and/or levels of nuclear radiation. The RFID tags would be activated and interrogated by the firefighters and control-station transceivers. Preferably, RFID tags would be configured to communicate with each other and with the firefighters units and the control station in an ordered sequence, with built-in redundancy. In a typical scenario, as firefighters moved through a building, they would scatter many RFID tags into smoke-obscured areas by use of a compressed-air gun. Alternatively or in addition, they would mark escape trails by dropping RFID tags at such points of interest as mantraps, hot spots, and trail waypoints. The RFID tags could be of different types, operating at different frequencies to identify their functions, and possibly responding by emitting audible beeps when activated by signals transmitted by transceiver units carried by nearby firefighters.

  11. Policy influences on community trail development.

    PubMed

    Eyler, Amy A; Brownson, Ross C; Evenson, Kelly R; Levinger, David; Maddock, Jay E; Pluto, Delores; Troped, Philip J; Schmid, Thomas L; Carnoske, Cheryl; Richards, Katherine L; Steinman, Lesley E

    2008-06-01

    This study explores processes and policies that facilitate the development of community trails. With funding from Active Living Research and the research framework of the Physical Activity Policy Research Network (PAPRN), we conducted a multiple-site case study. A total of six trails in Hawaii, Massachusetts, Missouri, North Carolina, South Carolina, and Washington were chosen for study. The goals of this case study were to identify the policy influences on trail development, explore the roles of key players in trail development, and compare and contrast findings from the different trails. Trail development can be a long process. Some of the trails took over a decade to complete because of funding, opposition, and roadblocks in the form of design standard policies. Work in trail development requires a team of many players, and it is necessary to balance their varied motives to accomplish a shared overall goal. Foresight through the master planning process is also a vital component of successful trail development. Finally, community involvement is key. Communities contemplating trail development should explore the effects of policy on the trail projects reported here to proactively identify potential influence. PMID:18469168

  12. 32 CFR Appendix D to Subpart M of... - Unauthorized Activities in Maneuver Training Areas

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...activities and combat games. Off-pavement motorcycle riding. Off-road vehicle...activities and combat games. Off-pavement motorcycle riding. Off-road vehicle...activities and combat games. Off-pavement motorcycle riding. Off-road...

  13. 32 CFR Appendix D to Subpart M of... - Unauthorized Activities in Maneuver Training Areas

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...activities and combat games. Off-pavement motorcycle riding. Off-road vehicle...activities and combat games. Off-pavement motorcycle riding. Off-road vehicle...activities and combat games. Off-pavement motorcycle riding. Off-road...

  14. 32 CFR Appendix D to Subpart M of... - Unauthorized Activities in Maneuver Training Areas

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...activities and combat games. Off-pavement motorcycle riding. Off-road vehicle...activities and combat games. Off-pavement motorcycle riding. Off-road vehicle...activities and combat games. Off-pavement motorcycle riding. Off-road...

  15. Experiences in teleoperation of land vehicles

    SciTech Connect

    McGovern, D.E.

    1987-10-01

    Teleoperation of land vehicles allows the removal of the operator from the vehicle to a remote location. This can greatly increase operator safety and comfort in applications such as security patrol or military combat. The cost includes system complexity and reduced system performance. All feedback on vehicle performance and on environmental conditions must pass through sensors, a communications channel, and displays. In particular, this requires vision to be transmitted by closed circuit television (CCTV), with a consequent degradation of information content. Vehicular teleoperation, as a result, places severe demands on the operator. Teleoperated land vehicles have been built and tested by many organizations including Sandia National Laboratories (SNL). The SNL fleet presently includes eight vehicles of varying capability. These vehicles have been operated using different types of controls, displays, and visual systems. Experimentation studying the effects of vision-system characteristics on off-road, remote driving has been performed for conditions of fixed camera versus steering coupled camera and color versus black and white video display. Additionally, much experience has been gained through system demonstrations and hardware development trials. This paper discusses the preliminary experimental findings and the results of the accumulated operational experience.

  16. Natural gas vehicles : Status, barriers, and opportunities.

    SciTech Connect

    Rood Werpy, M.; Santini, D.; Burnham, A.; Mintz, M.; Energy Systems

    2010-11-29

    In the United States, recent shale gas discoveries have generated renewed interest in using natural gas as a vehicular fuel, primarily in fleet applications, while outside the United States, natural gas vehicle use has expanded significantly in the past decade. In this report for the U.S. Department of Energy's Clean Cities Program - a public-private partnership that advances the energy, economic, and environmental security of the U.S. by supporting local decisions that reduce petroleum use in the transportation sector - we have examined the state of natural gas vehicle technology, current market status, energy and environmental benefits, implications regarding advancements in European natural gas vehicle technologies, research and development efforts, and current market barriers and opportunities for greater market penetration. The authors contend that commercial intracity trucks are a prime area for advancement of this fuel. Therefore, we examined an aggressive future market penetration of natural gas heavy-duty vehicles that could be seen as a long-term goal. Under this scenario using Energy Information Administration projections and GREET life-cycle modeling of U.S. on-road heavy-duty use, natural gas vehicles would reduce petroleum consumption by approximately 1.2 million barrels of oil per day, while another 400,000 barrels of oil per day reduction could be achieved with significant use of natural gas off-road vehicles. This scenario would reduce daily oil consumption in the United States by about 8%.

  17. Experiences in teleoperation of land vehicles

    NASA Technical Reports Server (NTRS)

    Mcgovern, Douglas E.

    1989-01-01

    Teleoperation of land vehicles allows the removal of the operator from the vehicle to a remote location. This can greatly increase operator safety and comfort in applications such as security patrol or military combat. The cost includes system complexity and reduced system performance. All feedback on vehicle performance and on environmental conditions must pass through sensors, a communications channel, and displays. In particular, this requires vision to be transmitted by close-circuit television with a consequent degradation of information content. Vehicular teleoperation, as a result, places severe demands on the operator. Teleoperated land vehicles have been built and tested by many organizations, including Sandia National Laboratories (SNL). The SNL fleet presently includes eight vehicles of varying capability. These vehicles have been operated using different types of controls, displays, and visual systems. Experimentation studying the effects of vision system characteristics on off-road, remote driving was performed for conditions of fixed camera versus steering-coupled camera and of color versus black and white video display. Additionally, much experience was gained through system demonstrations and hardware development trials. The preliminary experimental findings and the results of the accumulated operational experience are discussed.

  18. 30 CFR 75.603 - Temporary splice of trailing cable.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Temporary splice of trailing cable. 75.603... splice of trailing cable. One temporary splice may be made in any trailing cable. Such trailing cable may only be used for the next 24-hour period. No temporary splice shall be made in a trailing cable...

  19. 30 CFR 75.603 - Temporary splice of trailing cable.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Temporary splice of trailing cable. 75.603... splice of trailing cable. One temporary splice may be made in any trailing cable. Such trailing cable may only be used for the next 24-hour period. No temporary splice shall be made in a trailing cable...

  20. Delivery of tumor-homing TRAIL sensitizer with long-acting TRAIL as a therapy for TRAIL-resistant tumors.

    PubMed

    Oh, Yumin; Swierczewska, Magdalena; Kim, Tae Hyung; Lim, Sung Mook; Eom, Ha Na; Park, Jae Hyung; Na, Dong Hee; Kim, Kwangmeyung; Lee, Kang Choon; Pomper, Martin G; Lee, Seulki

    2015-12-28

    Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) has attracted great interest as a cancer therapy because it selectively induces death receptor (DR)-mediated apoptosis in cancer cells while sparing normal tissue. However, recombinant human TRAIL demonstrates limited therapeutic efficacy in clinical trials, possibly due to TRAIL-resistance of primary cancers and its inherent short half-life. Here we introduce drug delivery approaches to maximize in vivo potency of TRAIL in TRAIL-resistant tumor xenografts by (1) extending the half-life of the ligand with PEGylated TRAIL (TRAILPEG) and (2) concentrating a TRAIL sensitizer, selected from in vitro screening, in tumors via tumor-homing nanoparticles. Antitumor efficacy of TRAILPEG with tumor-homing sensitizer was evaluated in HCT116 and HT-29 colon xenografts. Western blot, real-time PCR, immunohistochemistry and cell viability assays were employed to investigate mechanisms of action and antitumor efficacy of the combination. We discovered that doxorubicin (DOX) sensitizes TRAIL-resistant HT-29 colon cancer cells to TRAIL by upregulating mRNA expression of DR5 by 60% in vitro. Intravenously administered free DOX does not effectively upregulate DR5 in tumor tissues nor demonstrate synergy with TRAILPEG in HT-29 xenografts, but rather introduces significant systemic toxicity. Alternatively, when DOX was encapsulated in hyaluronic acid-based nanoparticles (HAC/DOX) and intravenously administered with TRAILPEG, DR-mediated apoptosis was potentiated in HT-29 tumors by upregulating DR5 protein expression by 70% and initiating both extrinsic and intrinsic apoptotic pathways with reduced systemic toxicity compared to HAC/DOX or free DOX combined with TRAILPEG (80% vs. 40% survival rate; 75% vs. 34% tumor growth inhibition). This study demonstrates a unique approach to overcome TRAIL-based therapy drawbacks using sequential administration of a tumor-homing TRAIL sensitizer and long-acting TRAILPEG. PMID:26381901

  1. 75 FR 12254 - Official Trail Marker for the Ala Kahakai National Historic Trail

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-15

    ...SUMMARY: This notice issues the official trail marker insignia of the Ala Kahakai National Historic Trail. The original graphic image was developed as part of the Trail's comprehensive management and use Plan. It first came into public use in 2009. The...

  2. On the meteor trail spectra

    NASA Technical Reports Server (NTRS)

    Ovezgeldyev, O. G.; Mukhamednazarov, S.; Shafiev, R. I.; Maltsev, N. V.

    1987-01-01

    Meteor radiation appears as a result of collisions between meteoroid atoms and air molecules. Depending on duration, this radiation is usually divided into the following types: radiation of the meteor head; radiation of a coma surrounding or immediately following the meteor head; radiation of a trail formed as a result of fragments lagging behind or by the afterglow; and radiation of a meteor train forming from a tail as a result of various chemical and dynamical processes. To investigate physical processes caused by each of the above types, it is necessary to obtain the corresponding experimental data. The physical processes of the radiation and the measurement of the experimental data is discussed.

  3. TRAIL-R2-specific antibodies and recombinant TRAIL can synergise to kill cancer cells.

    PubMed

    Tuthill, M H; Montinaro, A; Zinngrebe, J; Prieske, K; Draber, P; Prieske, S; Newsom-Davis, T; von Karstedt, S; Graves, J; Walczak, H

    2015-04-16

    Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in cancer cells while sparing normal tissues. Despite promising preclinical results, few patients responded to treatment with recombinant TRAIL (Apo2L/Dulanermin) or TRAIL-R2-specific antibodies, such as conatumumab (AMG655). It is unknown whether this was due to intrinsic TRAIL resistance within primary human cancers or insufficient agonistic activity of the TRAIL-receptor (TRAIL-R)-targeting drugs. Fc? receptors (Fc?R)-mediated crosslinking increases the cancer-cell-killing activity of TRAIL-R2-specific antibodies in vivo. We tested this phenomenon using Fc?R-expressing immune cells from patients with ovarian cancer. However, even in the presence of high numbers of Fc?R-expressing immune cells, as found in ovarian cancer ascites, AMG655-induced apoptosis was not enabled to any significant degree, indicating that this concept may not translate into clinical use. On the basis of these results, we next set out to determine whether AMG655 possibly interferes with apoptosis induction by endogenous TRAIL, which could be expressed by immune cells. To do so, we tested how AMG655 affected apoptosis induction by recombinant TRAIL. This, however, resulted in the surprising discovery of a striking synergy between AMG655 and non-tagged TRAIL (Apo2L/TRAIL) in killing cancer cells. This combination was as effective in killing cancer cells as highly active recombinant isoleucine-zipper-tagged TRAIL (iz-TRAIL). The increased killing efficiency was due to enhanced formation of the TRAIL death-inducing signalling complex, enabled by concomitant binding of Apo2L/TRAIL and AMG655 to TRAIL-R2. The synergy of AMG655 with Apo2L/TRAIL extended to primary ovarian cancer cells and was further enhanced by combination with the proteasome inhibitor bortezomib or a second mitochondrial-derived activator of caspases (SMAC) mimetic. Importantly, primary human hepatocytes were not killed by the AMG655-Apo2L/TRAIL combination, also not when further combined with bortezomib or a SMAC mimetic. We therefore propose that clinical-grade non-tagged recombinant forms of TRAIL, such as dulanermin, could be combined with antibodies such as AMG655 to introduce a highly active TRAIL-R2-agonistic therapy into the cancer clinic. PMID:24909167

  4. Back in Time on a Mathematics Trail

    ERIC Educational Resources Information Center

    Moffett, Pamela

    2010-01-01

    The recently revised "Northern Ireland Primary Curriculum" recommends that teachers make use of the environment to extend children's understanding of mathematics. One approach to using the environment in mathematics is to take children on a mathematics trail. A mathematics trail uses the resources and features within the environment as a stimulus…

  5. Making Sense of Audit Trail Data

    ERIC Educational Resources Information Center

    Kennedy, Gregor E.; Judd, Terry S.

    2004-01-01

    In this paper we argue that the use of audit trail data for research and evaluation purposes has attracted scepticism due to real and perceived difficulties associated with the data's interpretation. We suggest that educational technology researchers and evaluators need to better understand how audit trail data can be processed and analysed…

  6. In-Trail Procedure (ITP) Algorithm Design

    NASA Technical Reports Server (NTRS)

    Munoz, Cesar A.; Siminiceanu, Radu I.

    2007-01-01

    The primary objective of this document is to provide a detailed description of the In-Trail Procedure (ITP) algorithm, which is part of the Airborne Traffic Situational Awareness In-Trail Procedure (ATSA-ITP) application. To this end, the document presents a high level description of the ITP Algorithm and a prototype implementation of this algorithm in the programming language C.

  7. Nature Trails for the Visually Impaired.

    ERIC Educational Resources Information Center

    Schwartz, Jonathan R.

    Many interpretive nature trails have been established for the visually impaired in recent years. The objectives of the investigation were to (a) identify what has been done in the past in the way of nature trail design for the visually impaired, (b) compare this with what professional workers for the visually impaired consider important in the…

  8. 36 CFR 261.13 - Motor vehicle use.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... System trails, and areas on National Forest System lands have been designated pursuant to 36 CFR 212.51... prohibition: (a) Aircraft; (b) Watercraft; (c) Over-snow vehicles; (d) Limited administrative use by...

  9. 36 CFR 261.13 - Motor vehicle use.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... System trails, and areas on National Forest System lands have been designated pursuant to 36 CFR 212.51... prohibition: (a) Aircraft; (b) Watercraft; (c) Over-snow vehicles; (d) Limited administrative use by...

  10. 36 CFR 261.13 - Motor vehicle use.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... System trails, and areas on National Forest System lands have been designated pursuant to 36 CFR 212.51... prohibition: (a) Aircraft; (b) Watercraft; (c) Over-snow vehicles; (d) Limited administrative use by...

  11. Trail impacts and trail impact management related to ecotourism visitation at Torres del Paine National Park, Chile

    USGS Publications Warehouse

    Farrell, T.A.; Marion, J.L.

    2002-01-01

    Ecotourism and protected area visitation in Central and South America are largely dependent upon a relatively undisturbed quality of natural resources. However, visitation may impact vegetation, soil, water and wildlife resources, and degrade visitor facilities such as recreation sites and trails. Findings are reported from trail impact research conducted at Torres del Paine National Park in Patagonia, Chile. The frequency and magnitude of selected trail impacts and the relative effect of the amount of use, vegetation type, trail position and trail grade are investigated. Findings differed from previous studies in that amount of use was significantly related to both trail width increases and trail erosion. Management actions to minimize trail impacts are offered.

  12. Evaluation of powertrain solutions for future tactical truck vehicle systems

    NASA Astrophysics Data System (ADS)

    Pisu, Pierluigi; Cantemir, Codrin-Gruie; Dembski, Nicholas; Rizzoni, Giorgio; Serrao, Lorenzo; Josephson, John R.; Russell, James

    2006-05-01

    The article presents the results of a large scale design space exploration for the hybridization of two off-road vehicles, part of the Future Tactical Truck System (FTTS) family: Maneuver Sustainment Vehicle (MSV) and Utility Vehicle (UV). Series hybrid architectures are examined. The objective of the paper is to illustrate a novel design methodology that allows for the choice of the optimal values of several vehicle parameters. The methodology consists in an extensive design space exploration, which involves running a large number of computer simulations with systematically varied vehicle design parameters, where each variant is paced through several different mission profiles, and multiple attributes of performance are measured. The resulting designs are filtered to choose the design tradeoffs that better satisfy the performance and fuel economy requirements. At the end, few promising vehicle configuration designs will be selected that will need additional detailed investigation including neglected metrics like ride and drivability. Several powertrain architectures have been simulated. The design parameters include the number of axles in the vehicle (2 or 3), the number of electric motors per axle (1 or 2), the type of internal combustion engine, the type and quantity of energy storage system devices (batteries, electrochemical capacitors or both together). An energy management control strategy has also been developed to provide efficiency and performance. The control parameters are tunable and have been included into the design space exploration. The results show that the internal combustion engine and the energy storage system devices are extremely important for the vehicle performance.

  13. Miles In Trail (MIT) Restrictions: A Perspective

    NASA Technical Reports Server (NTRS)

    Kopardekar, Parimal; Green, Steven; Roherty, Tom; Aston, John

    2003-01-01

    Miles-in-trail restrictions are issued to meet the airport and/or airspace capacity. The purpose of this paper is to review the currently practiced miles-in-trail operations for traffic flow management at a typical en route Air Traffic Control Center. The paper describes roles and considerations of both traffic management coordinators and the controllers in planning, coordination, execution, and monitoring of miles-in-trail restrictions. The paper addresses the type of decisions that traffic management coordinators must make and the different information required to plan and monitor miles-in-trail restrictions. The implications of miles-in-trail restrictions on controller workload are also addressed. Using the Cleveland center as an example, the paper also identified some challenging traffic situations that required miles-in-trail restrictions on a regular basis. The paper is expected to benefit the research and development community as it provides the current challenges in traffic flow management and strengths and weakness of miles-in-trail operations.

  14. Pheromone disruption of Argentine ant trail integrity

    USGS Publications Warehouse

    Suckling, D.M.; Peck, R.W.; Manning, L.M.; Stringer, L.D.; Cappadonna, J.; El-Sayed, A. M.

    2008-01-01

    Disruption of Argentine ant trail following and reduced ability to forage (measured by bait location success) was achieved after presentation of an oversupply of trail pheromone, (Z)-9-hexadecenal. Experiments tested single pheromone point sources and dispersion of a formulation in small field plots. Ant walking behavior was recorded and digitized by using video tracking, before and after presentation of trail pheromone. Ants showed changes in three parameters within seconds of treatment: (1) Ants on trails normally showed a unimodal frequency distribution of walking track angles, but this pattern disappeared after presentation of the trail pheromone; (2) ants showed initial high trail integrity on a range of untreated substrates from painted walls to wooden or concrete floors, but this was significantly reduced following presentation of a point source of pheromone; (3) the number of ants in the pheromone-treated area increased over time, as recruitment apparently exceeded departures. To test trail disruption in small outdoor plots, the trail pheromone was formulated with carnuba wax-coated quartz laboratory sand (1 g quartz sand/0.2 g wax/1 mg pheromone). The pheromone formulation, with a half-life of 30 h, was applied by rotary spreader at four rates (0, 2.5, 7.5, and 25 mg pheromone/m2) to 1- and 4-m2 plots in Volcanoes National Park, Hawaii. Ant counts at bait cards in treated plots were significantly reduced compared to controls on the day of treatment, and there was a significant reduction in ant foraging for 2 days. These results show that trail pheromone disruption of Argentine ants is possible, but a much more durable formulation is needed before nest-level impacts can be expected. ?? 2008 Springer Science+Business Media, LLC.

  15. Remote Sensing-based Models of Soil Vulnerability to Compaction and Erosion from Off-highway Vehicles

    NASA Astrophysics Data System (ADS)

    Villarreal, M. L.; Webb, R. H.; Norman, L.; Psillas, J.; Rosenberg, A.; Carmichael, S.; Petrakis, R.; Sparks, P.

    2014-12-01

    Intensive off-road vehicle use for immigration, smuggling, and security of the United States-Mexico border has prompted concerns about long-term human impacts on sensitive desert ecosystems. To help managers identify areas susceptible to soil erosion from vehicle disturbances, we developed a series of erosion potential models based on factors from the Revised Universal Soil Loss Equation (RUSLE), with particular focus on the management factor (P-factor) and vegetation cover (C-factor). To better express the vulnerability of soils to human disturbances, a soil compaction index (applied as the P-factor) was calculated as the difference in saturated hydrologic conductivity (Ks) between disturbed and undisturbed soils, which was then scaled up to remote sensing-based maps of vehicle tracks and digital soils maps. The C-factor was improved using a satellite-based vegetation index, which was better correlated with estimated ground cover (r2 = 0.77) than data derived from regional land cover maps (r2 = 0.06). RUSLE factors were normalized to give equal weight to all contributing factors, which provided more management-specific information on vulnerable areas where vehicle compaction of sensitive soils intersects with steep slopes and low vegetation cover. Resulting spatial data on vulnerability and erosion potential provide land managers with information to identify critically disturbed areas and potential restoration sites where off-road driving should be restricted to reduce further degradation.

  16. 36 CFR 212.81 - Use by over-snow vehicles.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Use by over-snow vehicles... TRAVEL MANAGEMENT Use by Over-Snow Vehicles § 212.81 Use by over-snow vehicles. (a) General. Use by over-snow vehicles on National Forest System roads and National Forest System trails and in areas...

  17. 36 CFR 212.81 - Use by over-snow vehicles.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Use by over-snow vehicles... TRAVEL MANAGEMENT Use by Over-Snow Vehicles § 212.81 Use by over-snow vehicles. (a) General. Use by over-snow vehicles on National Forest System roads and National Forest System trails and in areas...

  18. 36 CFR 212.81 - Use by over-snow vehicles.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Use by over-snow vehicles... TRAVEL MANAGEMENT Use by Over-Snow Vehicles § 212.81 Use by over-snow vehicles. (a) General. Use by over-snow vehicles on National Forest System roads and National Forest System trails and in areas...

  19. 36 CFR 212.81 - Use by over-snow vehicles.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Use by over-snow vehicles... TRAVEL MANAGEMENT Use by Over-Snow Vehicles § 212.81 Use by over-snow vehicles. (a) General. Use by over-snow vehicles on National Forest System roads and National Forest System trails and in areas...

  20. 36 CFR 212.81 - Use by over-snow vehicles.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Use by over-snow vehicles... TRAVEL MANAGEMENT Use by Over-Snow Vehicles § 212.81 Use by over-snow vehicles. (a) General. Use by over-snow vehicles on National Forest System roads and National Forest System trails and in areas...

  1. Trail marking by larvae of the eastern tent caterpillar.

    PubMed

    Fitzgerald, T D

    1976-11-26

    Eastern tent caterpillars that are successful foragers deposit trails as they return to the tent that are more attractive than the exploratory trails of the unfed larvae. The trails of these fed returning larvae attract unfed tentmates to food finds anre chemical factors account for the attractiveness of these trails. PMID:982055

  2. Immuno-LipoTRAIL: Targeted delivery of TRAIL-functionalized liposomal nanoparticles.

    PubMed

    Seifert, Oliver; Pollak, Nadine; Nusser, Anja; Steiniger, Frank; Rüger, Ronny; Pfizenmaier, Klaus; Kontermann, Roland E

    2014-05-21

    The TNF-related apoptosis-inducing ligand (TRAIL) is a powerful inducer of apoptosis in tumor cells; however, clinical studies with recombinant soluble TRAIL were rather disappointing. Here, we developed TRAIL-functionalized liposomes (LipoTRAIL, LT) to mimic membrane-displayed TRAIL for efficient activation of death receptors DR4 and DR5 and enhanced induction of apoptosis, which were combined with an anti-EGFR single-chain Fv fragment (scFv) for targeted delivery to EGFR-positive tumor cells. These immuno-LipoTRAILs (ILTs) bound specifically to EGFR-expressing cells (Colo205) and exhibited increased cytotoxicity compared with that of nontargeted LTs. Compared to that of the soluble TRAIL, the plasma half-life of the functionalized liposomes was strongly extended, and increased antitumor activity of LT and ILT was demonstrated in a xenograft tumor model. Thus, we established a multifunctional liposomal TRAIL formulation (ILT) with improved pharmacokinetic and pharmacodynamic behavior, characterized by targeted delivery and increased induction of apoptosis due to multivalent TRAIL presentation. PMID:24766622

  3. Miniature Trailing Edge Effector for Aerodynamic Control

    NASA Technical Reports Server (NTRS)

    Lee, Hak-Tae (Inventor); Bieniawski, Stefan R. (Inventor); Kroo, Ilan M. (Inventor)

    2008-01-01

    Improved miniature trailing edge effectors for aerodynamic control are provided. Three types of devices having aerodynamic housings integrated to the trailing edge of an aerodynamic shape are presented, which vary in details of how the control surface can move. A bucket type device has a control surface which is the back part of a C-shaped member having two arms connected by the back section. The C-shaped section is attached to a housing at the ends of the arms, and is rotatable about an axis parallel to the wing trailing edge to provide up, down and neutral states. A flip-up type device has a control surface which rotates about an axis parallel to the wing trailing edge to provide up, down, neutral and brake states. A rotating type device has a control surface which rotates about an axis parallel to the chord line to provide up, down and neutral states.

  4. 76 FR 44602 - Notice of Temporary Closure of Roads and Trails on Public Lands Adjacent to Big Willow Creek in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-26

    ...Roads and Trails on Public Lands Adjacent to Big Willow Creek in Payette County, ID AGENCY...SUMMARY: Notice is hereby given that the Big Willow closure to motorized vehicle use...1/4\\NW\\1/4\\ north and west of Big Willow Road. T. 8 N., R. 3 W.,...

  5. Pegylated TRAIL retains anti-leukemic cytotoxicity and exhibits improved signal transduction activity with respect to TRAIL.

    PubMed

    Gonelli, Arianna; Radillo, Oriano; Drioli, Sara; Rimondi, Erika; Secchiero, Paola; Maria Bonora, Gian

    2012-04-01

    To improve the pharmacokinetic profile of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) an N-terminal specific pegylation was performed to generate pegylated TRAIL (PEG-TRAIL). In in vitro experiments, we found that although PEG-TRAIL was slightly less efficient than recombinant TRAIL in promoting leukemic cell apoptosis, it showed an improved ability to promote migration of bone-marrow mesenchymal stem cells and to elicit the ERK1/2 intracellular signal transduction pathway. Overall, these data suggest that TRAIL pegylation retains, or even enhances, the biological activities of TRAIL relevant for its therapeutic applications. PMID:21125311

  6. A standard audit trail format

    SciTech Connect

    Bishop, M.

    1995-02-01

    The central role of audit trails, or (more properly) logs, in security monitoring needs little description, for it is too well known for any to doubt it. Auditing, or the analysis of logs, is a central part of security not only in computer system security but also in analyzing financial and other non-technical systems. As part of this process, it is often necessary to reconcile logs from different sources. This speaks of a need for a standard logging format. A standard log format robust enough to meet the needs of heterogeneity, transportability across various network protocols, and flexibility sufficient to meet a variety of needs in very different environments must satisfy two basic properties: extensibility and portability. This report presents the author`s proposed format for a standard log record. In section 3, he shows how and where the translation should be done, and in section 4 he demonstrates how log records from several disparate systems would be put into this format. Section 5 concludes with some observations and suggestions for future work.

  7. 76 FR 8992 - National Trails System Act and Railroad Rights-of-Way

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-16

    ... Surface Transportation Board 49 CFR Part 1152 National Trails System Act and Railroad Rights-of-Way AGENCY... railbanking and interim trail use under the National Trails System Act (Trails Act). DATES: Comments are due... railbanking and interim trail use under Section 8(d) of the National Trails System Act (Trails Act), 16...

  8. 75 FR 37462 - Official Trail Marker for the Captain John Smith Chesapeake National Historic Trail

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ... From the Federal Register Online via the Government Printing Office DEPARTMENT OF THE INTERIOR... AGENCY: National Parks Service, Interior. ACTION: Official Insignia, Designation. Authority: National... Trail system markers. The earlier design, which is still in use along the Trail, is also protected...

  9. Use and Nonuse of a Rail Trail Conversion for Physical Activity: Implications for Promoting Trail Use

    ERIC Educational Resources Information Center

    Price, Anna E.; Reed, Julian A.

    2014-01-01

    Background: There is limited research examining both use and nonuse of trails for physical activity. Purpose: Such research might enable health educators to better promote physical activity on trails.Methods:We used random digit dialing methods to survey 726 respondents in 2012. Results: The majority (75.1%) of respondents reported not using the…

  10. 76 FR 71601 - Record of Decision, Long Walk National Historic Trail Feasibility Study/Abbreviated Final...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-18

    ...Walk National Historic Trail Feasibility Study/Abbreviated Final Environmental...Walk National Historic Trail Feasibility Study...Walk National Historic Trail Feasibility Study, prepared by National...

  11. The Trail Pheromone of the Venomous Samsum Ant, Pachycondyla sennaarensis

    PubMed Central

    Mashaly, Ashraf Mohamed Ali; Ahmed, Ashraf Mohamed; Al—Abdullah, Mosa Abdullah; Al—Khalifa, Mohamed Saleh

    2011-01-01

    Ant species use branching networks of pheromone trails for orientation between nest and resources. The current study demonstrated that workers of the venomous samsum ant, Pachycondyla sennaarensis (Mayr) (Hymenoptera: Formicidae: Ponerinae), employ recruitment trail pheromones discharged from the Dufour's gland. Secretions of other abdomen complex glands, as well as hindgut gland secretions, did not evoke trail following. The optimum concentration of trail pheromone was found to be 0.1 gland equivalent/40 cm trail. This concentration demonstrated effective longevity for about one hour. This study also showed that P. sennaarensis and Tapinoma simrothi each respond to the trail pheromones of the other species as well as their own. PMID:21529253

  12. Trailing edge modifications for flatback airfoils.

    SciTech Connect

    Kahn, Daniel L.; van Dam, C.P.; Berg, Dale E.

    2008-03-01

    The adoption of blunt trailing edge airfoils (also called flatback airfoils) for the inboard region of large wind turbine blades has been proposed. Blunt trailing edge airfoils would not only provide a number of structural benefits, such as increased structural volume and ease of fabrication and handling, but they have also been found to improve the lift characteristics of thick airfoils. Therefore, the incorporation of blunt trailing edge airfoils would allow blade designers to more freely address the structural demands without having to sacrifice aerodynamic performance. These airfoils do have the disadvantage of generating high levels of drag as a result of the low-pressure steady or periodic flow in the near-wake of the blunt trailing edge. Although for rotors, the drag penalty appears secondary to the lift enhancement produced by the blunt trailing edge, high drag levels are of concern in terms of the negative effect on the torque and power generated by the rotor. Hence, devices are sought that mitigate the drag of these airfoils. This report summarizes the literature on bluff body vortex shedding and bluff body drag reduction devices and proposes four devices for further study in the wind tunnel.

  13. Therapeutic applications of TRAIL receptor agonists in cancer and beyond.

    PubMed

    Amarante-Mendes, Gustavo P; Griffith, Thomas S

    2015-11-01

    TRAIL/Apo-2L is a member of the TNF superfamily first described as an apoptosis-inducing cytokine in 1995. Similar to TNF and Fas ligand, TRAIL induces apoptosis in caspase-dependent manner following TRAIL death receptor trimerization. Because tumor cells were shown to be particularly sensitive to this cytokine while normal cells/tissues proved to be resistant along with being able to synthesize and release TRAIL, it was rapidly appreciated that TRAIL likely served as one of our major physiologic weapons against cancer. In line with this, a number of research laboratories and pharmaceutical companies have attempted to exploit the ability of TRAIL to kill cancer cells by developing recombinant forms of TRAIL or TRAIL receptor agonists (e.g., receptor-specific mAb) for therapeutic purposes. In this review article we will describe the biochemical pathways used by TRAIL to induce different cell death programs. We will also summarize the clinical trials related to this pathway and discuss possible novel uses of TRAIL-related therapies. In recent years, the physiological importance of TRAIL has expanded beyond being a tumoricidal molecule to one critical for a number of clinical settings - ranging from infectious disease and autoimmunity to cardiovascular anomalies. We will also highlight some of these conditions where modulation of the TRAIL/TRAIL receptor system may be targeted in the future. PMID:26343199

  14. 30 CFR 75.601 - Short circuit protection of trailing cables.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Short circuit protection of trailing cables...Trailing Cables § 75.601 Short circuit protection of trailing cables. [Statutory Provisions] Short circuit protection for trailing...

  15. 30 CFR 75.601 - Short circuit protection of trailing cables.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Short circuit protection of trailing cables...Trailing Cables § 75.601 Short circuit protection of trailing cables. [Statutory Provisions] Short circuit protection for trailing...

  16. 30 CFR 75.601 - Short circuit protection of trailing cables.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Short circuit protection of trailing cables...Trailing Cables § 75.601 Short circuit protection of trailing cables. [Statutory Provisions] Short circuit protection for trailing...

  17. 30 CFR 75.601 - Short circuit protection of trailing cables.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Short circuit protection of trailing cables...Trailing Cables § 75.601 Short circuit protection of trailing cables. [Statutory Provisions] Short circuit protection for trailing...

  18. 30 CFR 75.601 - Short circuit protection of trailing cables.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Short circuit protection of trailing cables...Trailing Cables § 75.601 Short circuit protection of trailing cables. [Statutory Provisions] Short circuit protection for trailing...

  19. 36 CFR 13.1308 - Harding Icefield Trail.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR NATIONAL PARK SYSTEM UNITS IN ALASKA Special Regulations-Kenai Fjords National Park General Provisions § 13.1308 Harding Icefield Trail. The Harding Icefield Trail from the...

  20. 36 CFR 13.1308 - Harding Icefield Trail.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR NATIONAL PARK SYSTEM UNITS IN ALASKA Special Regulations-Kenai Fjords National Park General Provisions § 13.1308 Harding Icefield Trail. The Harding Icefield Trail from the...

  1. 36 CFR 13.1308 - Harding Icefield Trail.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR NATIONAL PARK SYSTEM UNITS IN ALASKA Special Regulations-Kenai Fjords National Park General Provisions § 13.1308 Harding Icefield Trail. The Harding Icefield Trail from the...

  2. 36 CFR 13.1308 - Harding Icefield Trail.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR NATIONAL PARK SYSTEM UNITS IN ALASKA Special Regulations-Kenai Fjords National Park General Provisions § 13.1308 Harding Icefield Trail. The Harding Icefield Trail from the...

  3. 36 CFR 13.1308 - Harding Icefield Trail.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR NATIONAL PARK SYSTEM UNITS IN ALASKA Special Regulations-Kenai Fjords National Park General Provisions § 13.1308 Harding Icefield Trail. The Harding Icefield Trail from the...

  4. 1. Roaring Fork Motor Nature Trail, entrance sign. Great ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Roaring Fork Motor Nature Trail, entrance sign. - Great Smoky Mountains National Park Roads & Bridges, Roaring Fork Motor Nature Trail, Between Cherokee Orchard Road & U.S. Route 321, Gatlinburg, Sevier County, TN

  5. 7. Roaring Fork Motor Nature Trail, rocks along edge of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Roaring Fork Motor Nature Trail, rocks along edge of road. - Great Smoky Mountains National Park Roads & Bridges, Roaring Fork Motor Nature Trail, Between Cherokee Orchard Road & U.S. Route 321, Gatlinburg, Sevier County, TN

  6. 3. Roaring Fork Motor Nature Trail, view between second and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Roaring Fork Motor Nature Trail, view between second and third stops - Great Smoky Mountains National Park Roads & Bridges, Roaring Fork Motor Nature Trail, Between Cherokee Orchard Road & U.S. Route 321, Gatlinburg, Sevier County, TN

  7. 12. Roaring Fork Motor Nature Trail, place of a thousand ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Roaring Fork Motor Nature Trail, place of a thousand drips, view from road. - Great Smoky Mountains National Park Roads & Bridges, Roaring Fork Motor Nature Trail, Between Cherokee Orchard Road & U.S. Route 321, Gatlinburg, Sevier County, TN

  8. 5. Roaring Fork Motor Nature Trail, vista at stop three. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Roaring Fork Motor Nature Trail, vista at stop three. - Great Smoky Mountains National Park Roads & Bridges, Roaring Fork Motor Nature Trail, Between Cherokee Orchard Road & U.S. Route 321, Gatlinburg, Sevier County, TN

  9. 8. Roaring Fork Motor Nature Trail, handbuilt rock pile. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Roaring Fork Motor Nature Trail, hand-built rock pile. - Great Smoky Mountains National Park Roads & Bridges, Roaring Fork Motor Nature Trail, Between Cherokee Orchard Road & U.S. Route 321, Gatlinburg, Sevier County, TN

  10. 2. Roaring Fork Motor Nature Trail, road view before first ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Roaring Fork Motor Nature Trail, road view before first stop. - Great Smoky Mountains National Park Roads & Bridges, Roaring Fork Motor Nature Trail, Between Cherokee Orchard Road & U.S. Route 321, Gatlinburg, Sevier County, TN

  11. Roaring Fork Motor Nature Trail, Title Sheet Great Smoky ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Roaring Fork Motor Nature Trail, Title Sheet - Great Smoky Mountains National Park Roads & Bridges, Roaring Fork Motor Nature Trail, Between Cherokee Orchard Road & U.S. Route 321, Gatlinburg, Sevier County, TN

  12. 11. Roaring Fork Motor Nature Trail, boulders along road after ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Roaring Fork Motor Nature Trail, boulders along road after stop 13. - Great Smoky Mountains National Park Roads & Bridges, Roaring Fork Motor Nature Trail, Between Cherokee Orchard Road & U.S. Route 321, Gatlinburg, Sevier County, TN

  13. 6. Roaring Fork Motor Nature Trail, road view after stop ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Roaring Fork Motor Nature Trail, road view after stop four. - Great Smoky Mountains National Park Roads & Bridges, Roaring Fork Motor Nature Trail, Between Cherokee Orchard Road & U.S. Route 321, Gatlinburg, Sevier County, TN

  14. 9. Roaring Fork Motor Nature Trail, Reagan House. Great ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Roaring Fork Motor Nature Trail, Reagan House. - Great Smoky Mountains National Park Roads & Bridges, Roaring Fork Motor Nature Trail, Between Cherokee Orchard Road & U.S. Route 321, Gatlinburg, Sevier County, TN

  15. 30 CFR 56.12039 - Protection of surplus trailing cables.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Electricity § 56.12039 Protection of surplus trailing cables. Surplus trailing cables to shovels, cranes and similar...

  16. 30 CFR 57.12039 - Protection of surplus trailing cables.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Electricity Surface and Underground § 57.12039 Protection of surplus trailing cables. Surplus trailing cables to...

  17. 30 CFR 56.12038 - Attachment of trailing cables.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Electricity § 56.12038 Attachment of trailing cables. Trailing cables shall be attached to machines in a suitable manner to...

  18. 30 CFR 56.12039 - Protection of surplus trailing cables.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Electricity § 56.12039 Protection of surplus trailing cables. Surplus trailing cables to shovels, cranes and similar...

  19. 30 CFR 57.12038 - Attachment of trailing cables.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Electricity Surface and Underground § 57.12038 Attachment of trailing cables. Trailing cables shall be attached to...

  20. 30 CFR 57.12039 - Protection of surplus trailing cables.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Electricity Surface and Underground § 57.12039 Protection of surplus trailing cables. Surplus trailing cables to...

  1. 30 CFR 56.12038 - Attachment of trailing cables.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Electricity § 56.12038 Attachment of trailing cables. Trailing cables shall be attached to machines in a suitable manner to...

  2. 5. VIEW OF TRAIL WHERE IT PASSES THROUGH SAGE AREA, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. VIEW OF TRAIL WHERE IT PASSES THROUGH SAGE AREA, OWL CREEK IN CENTER OF PHOTOGRAPH. VIEW LOOKING EAST - Hole-in-the-Rock Trail, Running From Bluff Vicinity to Escalante, Garfield County, Bluff, San Juan County, UT

  3. 7. SHOWING METHOD OF SLEDDING WIND CABLE DOWN YAKI TRAIL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. SHOWING METHOD OF SLEDDING WIND CABLE DOWN YAKI TRAIL TO THE BRIDGE, WEIGHT OF CABLE AND DRUM APPROXIMATELY 2200 POUNDS - Kaibab Trail Suspension Bridge, Spanning Colorado River, Grand Canyon, Coconino County, AZ

  4. 27. YCC CREW THAT REBUILT PIMA POINT TRAILS. TIM BEALE, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. YCC CREW THAT REBUILT PIMA POINT TRAILS. TIM BEALE, NPS TRAILS, FRONT ROW RIGHT; BERNIE PONYAH, NPS YCC SUPERVISOR, BACK ROW RIGHT. - West Rim Drive, Between Grand Canyon Village & Hermit Rest, Grand Canyon, Coconino County, AZ

  5. Rails-to-Trails: A Valuable Resource for Outdoor Educators.

    ERIC Educational Resources Information Center

    Fischer, Jim

    1993-01-01

    Describes the rails-to-trails movement, particularly in Ontario, where abandoned railways are converted to trails for hiking, skiing, cycling, and horseback riding. Proposes the often controversial rails-to-trails issue as a resource for discussion in outdoor leadership classes, focusing on rural and urban viewpoints. Also suggests using the…

  6. Tracking of biogenic hydrodynamic trails in harbour seals (Phoca vitulina).

    PubMed

    Schulte-Pelkum, N; Wieskotten, S; Hanke, W; Dehnhardt, G; Mauck, B

    2007-03-01

    For seals hunting in dark and murky waters one source of sensory information for locating prey consists of fish-generated water movements, which they can detect using their highly sensitive mystacial vibrissae. As water movements in the wake of fishes can persist for several minutes, hydrodynamic trails of considerable length are generated. It has been demonstrated that seals can use their vibrissae to detect and track hydrodynamic trails generated artificially by miniature submarines. In the present study, we trained a harbour seal to swim predefined courses, thus generating biogenic hydrodynamic trails. The structure of these trails was measured using Particle Image Velocimetry. A second seal was trained to search for and track the trail after the trail-generating seal had left the water. Our trail-following seal was able to detect and accurately track the hydrodynamic trail, showing search patterns either mostly congruent with the trail or crossing the trail repeatedly in an undulatory way. The undulatory trail-following search pattern might allow a seal to relocate a lost trail or successfully track a fleeing, zigzagging prey fish. PMID:17297138

  7. 36 CFR 212.21 - Pacific Crest National Scenic Trail.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Pacific Crest National Scenic... AGRICULTURE TRAVEL MANAGEMENT Administration of the Forest Transportation System § 212.21 Pacific Crest National Scenic Trail. The Pacific Crest National Scenic Trail as defined by the National Trails...

  8. 36 CFR 212.21 - Pacific Crest National Scenic Trail.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Pacific Crest National Scenic... AGRICULTURE TRAVEL MANAGEMENT Administration of the Forest Transportation System § 212.21 Pacific Crest National Scenic Trail. The Pacific Crest National Scenic Trail as defined by the National Trails...

  9. 36 CFR 212.21 - Pacific Crest National Scenic Trail.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Pacific Crest National Scenic... AGRICULTURE TRAVEL MANAGEMENT Administration of the Forest Transportation System § 212.21 Pacific Crest National Scenic Trail. The Pacific Crest National Scenic Trail as defined by the National Trails...

  10. 36 CFR 212.21 - Pacific Crest National Scenic Trail.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Pacific Crest National Scenic... AGRICULTURE TRAVEL MANAGEMENT Administration of the Forest Transportation System § 212.21 Pacific Crest National Scenic Trail. The Pacific Crest National Scenic Trail as defined by the National Trails...

  11. 36 CFR 212.21 - Pacific Crest National Scenic Trail.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Pacific Crest National Scenic... AGRICULTURE TRAVEL MANAGEMENT Administration of the Forest Transportation System § 212.21 Pacific Crest National Scenic Trail. The Pacific Crest National Scenic Trail as defined by the National Trails...

  12. 29 CFR 1918.65 - Mechanically powered vehicles used aboard vessels.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...with the load trailing. (4) Steering knobs shall not be used unless the vehicle is equipped with power steering. (5) When mechanically powered...controls neutralized, brakes set and power shut off. Wheels shall be...

  13. 29 CFR 1918.65 - Mechanically powered vehicles used aboard vessels.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...with the load trailing. (4) Steering knobs shall not be used unless the vehicle is equipped with power steering. (5) When mechanically powered...controls neutralized, brakes set and power shut off. Wheels shall be...

  14. The OBIS Trail Module. Trial Version.

    ERIC Educational Resources Information Center

    Fairwell, Kay, Ed.; And Others

    Designed to allow youngsters aged 10 to 15 to experience the challenges and problems environmental investigators might face making an environmental impact study, the trial version of the Outdoor Biology Instructional Strategies (OBIS) Trail Module focuses on aspects of construction-related environment problems. Four activities are included in the…

  15. Trail Reidentification and Unlinkability in Distributed Databases

    E-print Network

    in this research are solely those of the author and do not necessarily reflect those of the United States be strengthened with formal computational models for privacy technology. In this work, trails are studied in two real world databases, including hospital visits derived from medical databases and weblogs derived from

  16. Interactive Media Audit Trails: Approaches and Issues.

    ERIC Educational Resources Information Center

    Misanchuk, Earl R.; Schwier, Richard

    This discussion of uses for audit trails in instructional research begins by pointing out that interactive media provide the learner with the opportunity to shape the program, and consequently, the learning experience. The paper focuses on one of the new questions for instructional designers that have come with the advent of these technologies,…

  17. Evolution of Dust Trails into Bands

    NASA Astrophysics Data System (ADS)

    Vokrouhlický, D.; Nesvorný, D.; Bottke, W. F.

    2008-01-01

    We use numerical simulations to investigate the production of dust trails by asteroid disruption events. Our work shows that asteroid trails evolve into pairs of dust bands over time. Coherent trails typically survive several tens of kyr before evolving into complete bands after ~1 Myr. The transition timescale depends sensitively on the location of the source breakup event in the main asteroid belt. Bands develop more efficiently from sources in the middle/outer belt than in the inner belt, which may not produce observable pairs of bands at all. The infrared structures produced by recent disruption events (<1 Myr) are characterized by a complicated and changing set of incomplete arcs and cusps. Their geometry depends both on the observer's position and on the source's location in terms of heliocentric distance and inclination to the ecliptic. We postulate that the broad orphan trails named C and D by Sykes in 1988 might have been produced by the formation of the Datura asteroid family 450+/-50 kyr ago. Additional work will be needed to test this link.

  18. Gorp, Again? Alternate Camp Trail Meals.

    ERIC Educational Resources Information Center

    Cameron, Layne

    1998-01-01

    By planning menus, repackaging food, packing the right spices, and being creative with aluminum foil and zip-top plastic bags, there is no reason to eat a bland trail meal again. Gives ten recipes, some with options for varying the dish. Eight of them serve two campers, two serve four to six. (TD)

  19. Sandstone Formation on the Navajo Loop Trail

    USGS Multimedia Gallery

    Views along the Navajo Loop Trail in Bryce Canyon National Park. Bryce Canyon is a unique sandstone formation in southern Utah. It is home to a large number of hoodoos, which are oddly shaped pillars of rock that formed due to different erosion rates for the dolomite that caps them and the sandston...

  20. Hoodoo on the Navajo Loop Trail

    USGS Multimedia Gallery

    Views along the Navajo Loop Trail in Bryce Canyon National Park. Bryce Canyon is a unique sandstone formation in southern Utah. It is home to a large number of hoodoos, which are oddly shaped pillars of rock that formed due to different erosion rates for the dolomite that caps them and the sandston...

  1. Certification trails and software design for testability

    NASA Technical Reports Server (NTRS)

    Sullivan, Gregory F.; Wilson, Dwight S.; Masson, Gerald M.

    1993-01-01

    Design techniques which may be applied to make program testing easier were investigated. Methods for modifying a program to generate additional data which we refer to as a certification trail are presented. This additional data is designed to allow the program output to be checked more quickly and effectively. Certification trails were described primarily from a theoretical perspective. A comprehensive attempt to assess experimentally the performance and overall value of the certification trail method is reported. The method was applied to nine fundamental, well-known algorithms for the following problems: convex hull, sorting, huffman tree, shortest path, closest pair, line segment intersection, longest increasing subsequence, skyline, and voronoi diagram. Run-time performance data for each of these problems is given, and selected problems are described in more detail. Our results indicate that there are many cases in which certification trails allow for significantly faster overall program execution time than a 2-version programming approach, and also give further evidence of the breadth of applicability of this method.

  2. Cedars on the Navajo Loop Trail

    USGS Multimedia Gallery

    Views along the Navajo Loop Trail in Bryce Canyon National Park. Bryce Canyon is a unique sandstone formation in southern Utah. It is home to a large number of hoodoos, which are oddly shaped pillars of rock that formed due to different erosion rates for the dolomite that caps them and the sandston...

  3. Snow on the Navajo Loop Trail

    USGS Multimedia Gallery

    Views along the Navajo Loop Trail in Bryce Canyon National Park. Bryce Canyon is a unique sandstone formation in southern Utah. It is home to a large number of hoodoos, which are oddly shaped pillars of rock that formed due to different erosion rates for the dolomite that caps them and the sandston...

  4. SAHM:VisTrails (Software for Assisted Habitat Modeling for VisTrails): training course

    USGS Publications Warehouse

    Holcombe, Tracy

    2014-01-01

    VisTrails is an open-source management and scientific workflow system designed to integrate the best of both scientific workflow and scientific visualization systems. Developers can extend the functionality of the VisTrails system by creating custom modules for bundled VisTrails packages. The Invasive Species Science Branch of the U.S. Geological Survey (USGS) Fort Collins Science Center (FORT) and the U.S. Department of the Interior’s North Central Climate Science Center have teamed up to develop and implement such a module—the Software for Assisted Habitat Modeling (SAHM). SAHM expedites habitat modeling and helps maintain a record of the various input data, the steps before and after processing, and the modeling options incorporated in the construction of an ecological response model. There are four main advantages to using the SAHM:VisTrails combined package for species distribution modeling: (1) formalization and tractable recording of the entire modeling process; (2) easier collaboration through a common modeling framework; (3) a user-friendly graphical interface to manage file input, model runs, and output; and (4) extensibility to incorporate future and additional modeling routines and tools. In order to meet increased interest in the SAHM:VisTrails package, the FORT offers a training course twice a year. The course includes a combination of lecture, hands-on work, and discussion. Please join us and other ecological modelers to learn the capabilities of the SAHM:VisTrails package.

  5. User Manual for ZOMBIE TRAIL Welcome to the world of Zombie Trail. In a land taken over by zombies, the

    E-print Network

    Wolfgang, Paul

    User Manual for ZOMBIE TRAIL Welcome to the world of Zombie Trail. In a land taken over by zombies .zip file to any directory of your choosing and running the ZombieTrail.exe file. Once the game loads a rocket launcher at a single zombie group, killing it. Priest ­ The priest will help your morale raise up

  6. Role of serum TRAIL level and TRAIL apoptosis gene expression in multiple sclerosis and relation to brain atrophy.

    PubMed

    Tawdy, Mohamed H; Abd El Nasser, Maged M; Abd El Shafy, Sanaa S; Nada, Mona A F; El Sirafy, Mohamed Nasr I; Magd, Amany Hussien Abol

    2014-09-01

    One of the presumed pathological mechanisms of multiple sclerosis (MS) is the failure of apoptosis of autoreactive T lymphocytes. This study aimed to determine the relationship of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mRNA gene expression ratio and serum TRAIL levels with MS and brain atrophy. This study was conducted on 53 relapsing-remitting Egyptian MS patients and 25 matched healthy volunteers. The expression of TRAIL in peripheral blood lymphocytes was analyzed by reverse transcription polymerase chain reaction, serum levels of soluble TRAIL (sTRAIL) were determined by enzyme-linked immunosorbent assay and brain MRI measured "black holes" and the bicaudate ratio as a measure of brain atrophy in all patients. The serum TRAIL level was lower in MS patients compared to controls but no difference was seen in the TRAIL mRNA gene expression ratio. No significant correlation was detected between the serum TRAIL level and the TRAIL mRNA expression ratio in either group. No statistically significant correlation was found between serum TRAIL levels or the TRAIL mRNA expression ratio with the number of black holes or the bicaudate ratio on MRI. Apoptosis of T lymphocytes is decreased in MS patients, which could be useful when designing treatments. There was no difference in the TRAIL mRNA gene expression ratio between MS patients and controls. PMID:24913933

  7. Spanwise morphing trailing edge on a finite wing

    NASA Astrophysics Data System (ADS)

    Pankonien, Alexander M.; Inman, Daniel J.

    2015-04-01

    Unmanned Aerial Vehicles are prime targets for morphing implementation as they must adapt to large changes in flight conditions associated with locally varying wind or large changes in mass associated with payload delivery. The Spanwise Morphing Trailing Edge concept locally varies the trailing edge camber of a wing or control surface, functioning as a modular replacement for conventional ailerons without altering the spar box. Utilizing alternating active sections of Macro Fiber Composites (MFCs) driving internal compliant mechanisms and inactive sections of elastomeric honeycombs, the SMTE concept eliminates geometric discontinuities associated with shape change, increasing aerodynamic performance. Previous work investigated a representative section of the SMTE concept and investigated the effect of various skin designs on actuation authority. The current work experimentally evaluates the aerodynamic gains for the SMTE concept for a representative finite wing as compared with a conventional, articulated wing. The comparative performance for both wings is evaluated by measuring the drag penalty associated with achieving a design lift coefficient from an off-design angle of attack. To reduce experimental complexity, optimal control configurations are predicted with lifting line theory and experimentally measured control derivatives. Evaluated over a range of off-design flight conditions, this metric captures the comparative capability of both concepts to adapt or "morph" to changes in flight conditions. Even with this simplistic model, the SMTE concept is shown to reduce the drag penalty due to adaptation up to 20% at off-design conditions, justifying the increase in mass and complexity and motivating concepts capable of larger displacement ranges, higher fidelity modelling, and condition-sensing control.

  8. Integrated vehicle control and guidance systems in unmanned ground vehicles for commercial applications

    NASA Astrophysics Data System (ADS)

    Kenyon, Chase H.

    1995-01-01

    While there is a lot of recent development in the entire IVHS field, very few have had the opportunity to combine the many areas of development into a single integrated `intelligent' unmanned vehicle. One of our systems was developed specifically to serve a major automobile manufacturer's need for an automated vehicle chassis durability test facility. Due to the severity of the road surface human drivers could not be used. A totally automated robotic vehicle driver and guidance system was necessary. In order to deliver fixed price commercial projects now, it was apparent system and component costs were of paramount importance. Cyplex has developed a robust, cost effective single wire guidance system. This system has inherent advantages in system simplicity. Multi-signal (per vehicle lane) systems complicate path planning and layout when multiple lanes and lane changes are required, as on actual highways. The system has demonstrated high enough immunity to rain and light snow cover that normal safety reductions in speed are adequate to stay within the required system performance envelope. This system and it's antenna interface have shown the ability to guide the vehicle at slow speeds (10 MPH) with a tracking repeatability of plus or minus 1/8 of an inch. The basic guide and antenna system has been tested at speeds up to 80 mph. The system has inherently superior abilities for lane changes and precision vehicle placement. The operation of this system will be described and the impact of a system that is commercially viable now for highway and off road use will be discussed.

  9. Vegetation moderates impacts of tourism usage on bird communities along roads and hiking trails.

    PubMed

    Wolf, Isabelle D; Hagenloh, Gerald; Croft, David B

    2013-11-15

    Bird communities inhabiting ecosystems adjacent to recreational tracks may be adversely affected by disturbance from passing tourism traffic, vehicle-related mortality, habitat alteration and modified biotic relationships such as the increase of strong competitors. This study investigated the effects of tourist usage of roads vs. hiking trails on bird communities in gorges of the Flinders Ranges, a popular South Australian tourist destination in the arid-lands. High tourist usage along roads decreased the individual abundance and species richness of birds relative to low usage trails. The decrease in species richness, though less pronounced, also occurred at high-usage sites along trails. Changes in the species response to recreational disturbance/impacts varied depending on the ecology of the species. Bigger, more competitive birds with a generalist diet were overrepresented at high-usage sites along roads and trails. Species using microhabitats in lower vegetation layers were more sensitive. However, structural and floristic complexity of vegetation was a more important factor influencing bird abundance than tourist usage. Sites with a better developed shrub and tree layer sustained higher species abundance and richer communities. Importantly, vegetation qualities moderated the negative effect of high usage on the individual abundance of birds along roads, to the extent that such an effect was absent at sites with the best developed shrub and tree layer. To protect avifauna along recreational tracks in arid-lands gorges, we recommend the closure of some gorges or sections for vehicle or any access. Further, open space particularly for camping needs to be minimized as it creates areas of high tourist usage with modified habitat that provides birds with little buffer from disturbance. PMID:23954389

  10. Driver's adaptive glance behavior to in-vehicle information systems.

    PubMed

    Peng, Yiyun; Boyle, Linda Ng

    2015-12-01

    The purpose of this study was to examine the adaptive behavior of drivers as they engage with in-vehicle devices over time and in varying driving situations. Behavioral adaptation has been shown to occur among drivers after prolonged use of in-vehicle devices, but few studies have examined drivers' risk levels across different driving demands. A multi-day simulator study was conducted with 28 young drivers (under 30 years old) as they engaged in different text entry and reading tasks while driving in two different traffic conditions. Cluster analysis was used to categorize drivers based on their risk levels and random coefficient models were used to assess changes in drivers' eye glance behavior. Glance duration significantly increased over time while drivers were performing text entry tasks but not for text reading tasks. High-risk drivers had longer maximum eyes-off-road when performing long text entry tasks compared to low-risk drivers, and this difference increased over time. The traffic condition also had a significant impact on drivers' glance behavior. This study suggests that drivers may exhibit negative behavioral adaptation as they become more comfortable with using in-vehicle technologies over time. Results of this paper may provide guidance for the design of in-vehicle devices that adapt based on the context of the situation. It also demonstrates that random coefficient models can be used to obtain better estimations of driver behavior when there are large individual differences. PMID:26406538

  11. The trail making test in India

    PubMed Central

    Bhatia, Triptish; Shriharsh, Vandana; Adlakha, Saurabh; Bisht, Vivek; Garg, Kapila; Deshpande, Smita N.

    2007-01-01

    The trail making test (TMT) is a short and convenient estimate of cognitive functions, principally attention and working memory. Like most neuropsychological tests, it is derived from and primarily applicable to English-speaking individuals. Norms for other ethnic minorities may differ significantly. The application of majority or mixed norms to specific ethnic subcultures may introduce systematic bias. To examine the impact of an English test on primarily nonEnglish-speaking individuals, outpatients attending the dermatology department of a large Indian hospital (n = 120) were asked to complete the English version of the TMT. The time taken to complete the TRAILS was unexpectedly long, although all the subjects scored within normal limits on the modified mini mental status examination and a test for general knowledge. Possible reasons for the delayed completion times are discussed below. PMID:20711393

  12. Mating system shifts on the trailing edge

    PubMed Central

    Levin, Donald A.

    2012-01-01

    Background The trailing edges of species ranges are becoming a subject of increasing interest as the environment changes due to global warming. Trailing edge populations are likely to face extinction because of a decline in numbers and an inability to evolve new adaptations with sufficient speed. Discussions of character change in the trailing edge have focused on physiological, exomorphic and phenological traits. The mating pattern within populations has not been part of the discourse, in spite of the fact that the mating pattern may affect the ability of populations to respond to environmental change and to maintain their sizes. In this paper, the case is made that a substantial increase in self-fertilization rates may occur via plastic responses to stress. Scope and Conclusions Small populations on the trailing edge are especially vulnerable to environmental change because of inadequate levels of cross-fertilization. Evidence is presented that a deficiency of cross-seed production is due to inadequate pollinator services and a paucity of self-incompatibility alleles within populations. Evidence also is presented that if plants are self-compatible, self-fertilization may compensate in part for this deficiency through a stress-induced increase in levels of self-compatibility and stress-induced alterations in floral morphology that elevate self-pollination. Whereas increased self-fertility may afford populations the time to adapt to their changing environments, it can be concluded that increased selfing is not a panacea for the ills of environmental change, because it will lead to substantial reductions in genetic diversity, which may render adaptation unlikely. PMID:21980190

  13. Stability of trailing vortices with radial stratification

    NASA Astrophysics Data System (ADS)

    Fontane, Jerome; Joly, Laurent; Audouin, Auriane

    2011-11-01

    We look at the effects of the radial density stratification on the stability of the q-vortex, a commonly accepted model for aircraft trailing vortices. It has been demonstrated that the 2D Lamb-Oseen vortex develops a Rayleigh-Taylor instability when its core is heavier than the surrounding fluid (Joly, Fontane & Chassaing 2005, Sipp et al 2005). The underlying mechanism relies on baroclinic vorticity generation due to any misalignment between the density gradient and the centripetal acceleration field. The instability is triggered provided that the density decreases radially somewhere in the vortex core. This mechanism is also active in the 3D trailing vortex and affects its stability characteristics due to the addition of an axial component in the acceleration field. We show that the unstable center modes of the homogeneous case (Fabre & Jacquin 2004) are promoted in a q-vortex with a heavy core. Their growth rate increases while their m-spiral structure is preserved. For an Atwood number At = 0 . 5 , their predicted growth rate can be ten times the ones found in the homogeneous case. Furthermore, the unstable domain is extended far beyond the neutral curve in the homogeneous case, with unstable modes observed for Swirl numbers up to q = 5 . It is argued here that corresponding density perturbations could eventually lead to the development of new and original strategies to decrease the lifespan of aircraft trailing vortices and greatly reduce their unwanted side-effects on contrails persistence and air traffic regulations.

  14. The Effect of Nozzle Trailing Edge Thickness on Jet Noise

    NASA Technical Reports Server (NTRS)

    Henderson, Brenda; Kinzie, Kevin; Haskin, Henry

    2004-01-01

    The effect of nozzle trailing edge thickness on broadband acoustic radiation and the production of tones is investigated for coannular nozzles. Experiments were performed for a core nozzle trailing edge thickness between 0.38 mm and 3.17 mm. The on-set of discrete tones was found to be predominantly affected by the velocity ratio, the ratio of the fan velocity to the core velocity, although some dependency on trailing edge thickness was also noted. For a core nozzle trailing edge thickness greater than or equal to 0.89 mm, tones were produced for velocity ratios between 0.91 and 1.61. For a constant nozzle trailing edge thickness, the frequency varied almost linearly with the core velocity. The Strouhal number based on the core velocity changed with nozzle trailing edge thickness and varied between 0.16 and 0.2 for the core nozzles used in the experiments. Increases in broadband noise with increasing trailing edge thickness were observed for tone producing and non-tone producing conditions. A variable thickness trailing edge (crenellated) nozzle resulted in no tonal production and a reduction of the broadband trailing edge noise relative to that of the corresponding constant thickness trailing edge.

  15. A promising "TRAIL" of tanshinones for cancer therapy.

    PubMed

    Ho, Tsing-Fen; Chang, Chia-Che

    2015-11-01

    An ideal cancer therapy specifically targets cancer cells while sparing normal tissues. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) elicits apoptosis by engaging its cognate death receptors (DRs-namely, DR4 and DR5. The cancer cell-selective proapoptotic action of TRAIL is highly attractive for cancer therapy, but clinical application of TRAIL is rather limited due to tumors' inherent or acquired TRAIL resistance. Combining TRAIL with agents that reverse resistance to it has proved promising in the sensitization of TRAIL-induced apoptosis. Noteworthy, natural compounds have already been validated as potential resources for TRAIL sensitizers. In this review, we focus on the recently identified TRAILsensitizing effect of tanshinones, the anticancer ingredients of the medicinal plant Salvia miltiorrhiza (Danshen in Chinese). Research from our laboratories and others have revealed the synergy of a tanshinones-TRAIL combination in diverse types of cancer cells through up-regulation of DR5 and/or down-regulation of antiapoptotic proteins such as survivin. Thus, in addition to their anticancer mechanisms, tanshinones as TRAIL sensitizers hold great potential to be translated to TRAIL-based therapeutic modalities for combatting cancer. PMID:26621311

  16. TRAIL and targeting cancer cells: between promises and obstacles.

    PubMed

    Limami, Y; Pinon, A; Riaz, A; Simon, A

    2015-01-01

    Targeting cancer cells is one of the challenges of current treatment strategies. TRAIL represents a promising therapeutic approach and over the past decades there was an increased interest in targeting TRAIL signaling to treat cancer. Indeed, TRAIL can specifically target cancer cells and exhibits very low cytotoxicity towards normal cells. However, rapidly accumulating experimental evidence has started to shed light on multiple factors which induce resistance against TRAIL in cancer cells. This resistance consists of various mechanisms including downregulation of death receptors and caspase—8 and overexpression of decoy receptors as well as antiapoptotic factors such as members of Bcl—2 family. Even if several studies focused on elucidating those resistance mechanisms, there still remain gray areas that need to be fully elucidated. Thus, therapeutic approaches could consist of targeting both resistance signaling pathways and TRAIL signaling to enhance TRAIL therapy efficiency. PMID:26518894

  17. Trail impact monitoring in Rocky Mountain National Park, USA

    NASA Astrophysics Data System (ADS)

    Svajda, J.; Korony, S.; Brighton, I.; Esser, S.; Ciapala, S.

    2015-11-01

    This paper examines impacts of increased visitation leading to human trampling of vegetation and soil along several trails in Rocky Mountain National Park (RMNP) to understand how abiotic factors and level of use can influence trail conditions. RMNP is one of the most visited national parks in the USA with 3.3 million visitors in 2012 across 1075 km2 and 571 km of hiking trails. 95 % of the park is designated wilderness making the balance between preservation and visitor use challenging. This research involves the application of trail condition assessments to 56 km of trails to determine prevailing factors and what, if any, connection between them exist. The study looked at a variety of inventory and impact indicators and standards to determine their importance and to develop a baseline condition of trails. The data can be used for future comparison and evaluation of development trends. We found that trail widening (mean trail width 88.9 cm) and soil loss (cross sectional area 172.7 cm2) are the most visible effects of trail degradation. Further statistical analyses of data identified the role and influence of various factors (e.g. use level and topography). Insights into the influence of these factors can lead to the selection of appropriate management measures to avoid or minimize negative consequences from increased visitation.

  18. A survey of debris trails from short-period comets

    E-print Network

    William T. Reach; Michael S. Kelley; Mark V. Sykes

    2007-04-17

    We observed 34 comets using the 24 micron camera on the Spitzer Space Telescope. Each image contains the nucleus and covers at least 10^6 km of each comet's orbit. Debris trails due to mm-sized or larger particles were found along the orbits of 27 comets; 4 comets had small-particle dust tails and a viewing geometry that made debris trails impossible to distinguish; and only 3 had no debris trail despite favorable observing conditions. There are now 30 Jupiter-family comets with known debris trails, of which 22 are reported in this paper for the first time. The detection rate is >80%, indicating that debris trails are a generic feature of short-period comets. By comparison to orbital calculations for particles of a range of sizes ejected over 2 yr prior to observation, we find that particles comprising 4 debris trails are typically mm-sized while the remainder of the debris trails require particles larger than this. The lower-limit masses of the debris trails are typically 10^11 g, and the median mass loss rate is 2 kg/s. The mass-loss rate in trail particles is comparable to that inferred from OH production rates and larger than that inferred from visible-light scattering in comae.

  19. GENERATING TRAILS AUTOMATICALLY 1 Generating Trails Automatically, to Aid Navigation when you Revisit an Environment

    E-print Network

    Ruddle, Roy

    , pages 562-574, published by The MIT Press.] Roy A Ruddle School of Computing University of Leeds Leeds), and uses string-matching to identify similar sequences of movement and derive the person's primary trail snow or forest, and to reduce the cognitive effort involved when traveling from one place to another

  20. An aerial-photographic assessment of reenacted handcart treks on a section of the Mormon Pioneer National Historic Trail, Fremont County, Wyoming

    USGS Publications Warehouse

    McDougal, Robert R.; Waltermire, Robert G.; Aldridge, Cameron L.; Germaine, Stephen S.; Nielsen, Scott E.; Nielsen, Charlene C.; Hanson, Leanne; Bowen, Zachary H.

    2008-01-01

    Based on these results, there are identifiable management considerations. Toilet and rest sites need to be carefully located relative to where sensitive vegetation or soils occur. The analyses presented here indicate that limiting motorized vehicle use needs to be a priority over that of adjusting the number of trekkers. Additionally, monitoring of the Trail from Sixth Crossing to Rock Creek Hollow segment needs to consider explicit management targets, such as minimum acceptable levels of bare ground or trail width, and the establishment of permanent monitoring plots to evaluate targets and measure responses to altered management activities.

  1. Transportation Energy Futures Series: Potential for Energy Efficiency Improvement Beyond the Light-Duty-Vehicle Sector

    SciTech Connect

    Vyas, A. D.; Patel, D. M.; Bertram, K. M.

    2013-03-01

    Considerable research has focused on energy efficiency and fuel substitution options for light-duty vehicles, while much less attention has been given to medium- and heavy-duty trucks, buses, aircraft, marine vessels, trains, pipeline, and off-road equipment. This report brings together the salient findings from an extensive review of literature on future energy efficiency options for these non-light-duty modes. Projected activity increases to 2050 are combined with forecasts of overall fuel efficiency improvement potential to estimate the future total petroleum and greenhouse gas (GHG) emissions relative to current levels. This is one of a series of reports produced as a result of the Transportation Energy Futures (TEF) project, a Department of Energy-sponsored multi-agency project initiated to pinpoint underexplored strategies for abating GHGs and reducing petroleum dependence related to transportation.

  2. Transportation Energy Futures Series. Potential for Energy Efficiency Improvement Beyond the Light-Duty-Vehicle Sector

    SciTech Connect

    Vyas, A. D.; Patel, D. M.; Bertram, K. M.

    2013-02-01

    Considerable research has focused on energy efficiency and fuel substitution options for light-duty vehicles, while much less attention has been given to medium- and heavy-duty trucks, buses, aircraft, marine vessels, trains, pipeline, and off-road equipment. This report brings together the salient findings from an extensive review of literature on future energy efficiency options for these non-light-duty modes. Projected activity increases to 2050 are combined with forecasts of overall fuel efficiency improvement potential to estimate the future total petroleum and greenhouse gas (GHG) emissions relative to current levels. This is one of a series of reports produced as a result of the Transportation Energy Futures (TEF) project, a Department of Energy-sponsored multi-agency project initiated to pinpoint underexplored strategies for abating GHGs and reducing petroleum dependence related to transportation.

  3. 30 CFR 77.605 - Breaking trailing cable and power cable connections.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...Breaking trailing cable and power cable connections. ...DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH...SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Trailing Cables...Breaking trailing cable and power cable connections....

  4. 30 CFR 77.605 - Breaking trailing cable and power cable connections.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Breaking trailing cable and power cable connections. ...DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH...SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Trailing Cables...Breaking trailing cable and power cable connections....

  5. 30 CFR 77.605 - Breaking trailing cable and power cable connections.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...Breaking trailing cable and power cable connections. ...DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH...SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Trailing Cables...Breaking trailing cable and power cable connections....

  6. 30 CFR 77.605 - Breaking trailing cable and power cable connections.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...Breaking trailing cable and power cable connections. ...DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH...SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Trailing Cables...Breaking trailing cable and power cable connections....

  7. 30 CFR 77.605 - Breaking trailing cable and power cable connections.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...Breaking trailing cable and power cable connections. ...DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH...SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Trailing Cables...Breaking trailing cable and power cable connections....

  8. 30 CFR 77.600 - Trailing cables; short-circuit protection; disconnecting devices.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 false Trailing cables; short-circuit protection; disconnecting devices...77.600 Trailing cables; short-circuit protection; disconnecting devices. Short-circuit protection for trailing...

  9. 30 CFR 77.600 - Trailing cables; short-circuit protection; disconnecting devices.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 false Trailing cables; short-circuit protection; disconnecting devices...77.600 Trailing cables; short-circuit protection; disconnecting devices. Short-circuit protection for trailing...

  10. 30 CFR 77.600 - Trailing cables; short-circuit protection; disconnecting devices.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 false Trailing cables; short-circuit protection; disconnecting devices...77.600 Trailing cables; short-circuit protection; disconnecting devices. Short-circuit protection for trailing...

  11. 30 CFR 77.600 - Trailing cables; short-circuit protection; disconnecting devices.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 false Trailing cables; short-circuit protection; disconnecting devices...77.600 Trailing cables; short-circuit protection; disconnecting devices. Short-circuit protection for trailing...

  12. 30 CFR 77.600 - Trailing cables; short-circuit protection; disconnecting devices.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 false Trailing cables; short-circuit protection; disconnecting devices...77.600 Trailing cables; short-circuit protection; disconnecting devices. Short-circuit protection for trailing...

  13. 77 FR 1723 - Notice of Availability, Potomac Heritage National Scenic Trail

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-11

    ...3991-0101-SZS] Notice of Availability, Potomac Heritage National Scenic Trail AGENCY: National...Management and Interpretation of Potomac Heritage National Scenic Trail Segments and for...Management and Interpretation of Potomac Heritage National Scenic Trail Segments and...

  14. An Experimental Investigation of Trailing Edge Acoustics

    NASA Astrophysics Data System (ADS)

    Shannon, Daniel W.

    2005-11-01

    Measurements of the convected vorticity field in the near wake of a blunt asymmetric trailing edge has lead to the hypothesis that large scale turbulence related to a vortex shedding modulates the broadband sound produced by smaller scale turbulent motions. This paper will focus on efforts to support this hypothesis through the simultaneous measurement of the unsteady pressure on the model surface and the far field acoustic pressure. The acoustic data were acquired in an anechoic wind tunnel utilizing a pair of phased microphone arrays containing 40 condenser microphones each. Correlations between the surface pressure and the acoustic pressure suggest that the tonal noise is more closely related to the unsteady surface pressure on the attached pressure side of the model and that the broadband noise is correlated with the surface pressures over the separated suction side of the trailing edge. An analysis of the broadband noise as a function of the phase of the vortex shedding process suggests that the both the surface pressure and the acoustic pressure are modulated by the vortex shedding motions.

  15. Caspase-8 activation by TRAIL monotherapy predicts responses to IAPi and TRAIL combination treatment in breast cancer cell lines

    PubMed Central

    Polanski, R; Vincent, J; Polanska, U M; Petreus, T; Tang, E K Y

    2015-01-01

    The discovery of cancer cell-selective tumour necrosis factor-related apoptosis inducing ligand (TRAIL)-induced apoptosis generated broad excitement and development of TRAIL receptor agonists (TRA) as potential cancer therapy. Studies demonstrating the synergistic combination effect of SMAC mimetics and TRA further suggested potentially effective treatment in multiple tumour settings. However, predictive biomarkers allowing identification of patients that could respond to treatment are lacking. Here, we described a high throughput combination screen conducted across a panel of 31 breast cancer cell lines in which we observed highly synergistic activity between TRAIL and the inhibitors of apoptosis proteins (IAP) inhibitor (IAPi) AZD5582 in ~30% of cell lines. We detected no difference in the expression levels of the IAPi or TRAIL-targeted proteins or common modulators of the apoptotic pathway between the sensitive and resistant cell lines. Synergistic combination effect of AZD5582 and TRAIL correlated with sensitivity to TRAIL, but not to AZD5582 as a single agent. TRAIL treatment led to significantly greater activity of Caspase-8 in sensitive than in resistant cell lines (P=0.002). The majority (12/14) of AZD5582+TRAIL-resistant cell lines retained a functional cell death pathway, as they were sensitive to AZD5582+TNF? combination treatment. This suggested that failure of the TRAIL receptor complex to transduce the death signal to Caspase-8 underlies AZD5582+TRAIL resistance. We developed a 3D spheroid assay and demonstrated its suitability for the ex vivo analysis of the Caspase-8 activity as a predictive biomarker. Altogether, our study demonstrated a link between the functionality of the TRAIL receptor pathway and the synergistic activity of the IAPi+TRA combination treatment. It also provided a rationale for development of the Caspase-8 activity assay as a functional predictive biomarker that could allow better prediction of the response to IAPi+TRA-based therapies than the analysis of expression levels of protein biomarkers. PMID:26426685

  16. Caspase-8 activation by TRAIL monotherapy predicts responses to IAPi and TRAIL combination treatment in breast cancer cell lines.

    PubMed

    Polanski, R; Vincent, J; Polanska, U M; Petreus, T; Tang, E K Y

    2015-01-01

    The discovery of cancer cell-selective tumour necrosis factor-related apoptosis inducing ligand (TRAIL)-induced apoptosis generated broad excitement and development of TRAIL receptor agonists (TRA) as potential cancer therapy. Studies demonstrating the synergistic combination effect of SMAC mimetics and TRA further suggested potentially effective treatment in multiple tumour settings. However, predictive biomarkers allowing identification of patients that could respond to treatment are lacking. Here, we described a high throughput combination screen conducted across a panel of 31 breast cancer cell lines in which we observed highly synergistic activity between TRAIL and the inhibitors of apoptosis proteins (IAP) inhibitor (IAPi) AZD5582 in ~30% of cell lines. We detected no difference in the expression levels of the IAPi or TRAIL-targeted proteins or common modulators of the apoptotic pathway between the sensitive and resistant cell lines. Synergistic combination effect of AZD5582 and TRAIL correlated with sensitivity to TRAIL, but not to AZD5582 as a single agent. TRAIL treatment led to significantly greater activity of Caspase-8 in sensitive than in resistant cell lines (P=0.002). The majority (12/14) of AZD5582+TRAIL-resistant cell lines retained a functional cell death pathway, as they were sensitive to AZD5582+TNF? combination treatment. This suggested that failure of the TRAIL receptor complex to transduce the death signal to Caspase-8 underlies AZD5582+TRAIL resistance. We developed a 3D spheroid assay and demonstrated its suitability for the ex vivo analysis of the Caspase-8 activity as a predictive biomarker. Altogether, our study demonstrated a link between the functionality of the TRAIL receptor pathway and the synergistic activity of the IAPi+TRA combination treatment. It also provided a rationale for development of the Caspase-8 activity assay as a functional predictive biomarker that could allow better prediction of the response to IAPi+TRA-based therapies than the analysis of expression levels of protein biomarkers. PMID:26426685

  17. Audit Trail Management System in Community Health Care Information Network.

    PubMed

    Nakamura, Naoki; Nakayama, Masaharu; Nakaya, Jun; Tominaga, Teiji; Suganuma, Takuo; Shiratori, Norio

    2015-01-01

    After the Great East Japan Earthquake we constructed a community health care information network system. Focusing on the authentication server and portal server capable of SAML&ID-WSF, we proposed an audit trail management system to look over audit events in a comprehensive manner. Through implementation and experimentation, we verified the effectiveness of our proposed audit trail management system. PMID:26262379

  18. Tetravalent antibody-scTRAIL fusion proteins with improved properties.

    PubMed

    Seifert, Oliver; Plappert, Aline; Fellermeier, Sina; Siegemund, Martin; Pfizenmaier, Klaus; Kontermann, Roland E

    2014-01-01

    We applied the immunoglobulin E (IgE) heavy-chain domain 2 (EHD2) as the covalently linked homodimerization module to generate antibody-scTRAIL fusion proteins. By fusing a humanized single-chain fragment variable (scFv) directed against EGFR to the N-terminus of the EHD2 and a single-chain derivative of TRAIL (scTRAIL) to the C-terminus of the EHD2, we produced a dimeric, tetravalent fusion protein. The fusion protein retained its binding activity for EGFR and TRAIL receptors. In vitro, the targeted antibody-scTRAIL fusion protein exhibited an approximately 8- to 18-fold increased cytotoxic activity compared with the untargeted EHD2-scTRAIL fusion protein. This resulted in increased antitumor activity in a subcutaneous Colo205 xenograft tumor murine model. In summary, the scFv-EHD2-scTRAIL fusion protein combines target cell selectivity with an increased TRAIL activity leading to improved antitumor activities. PMID:24092811

  19. Geoscience exhibit displays `Trail of Time' By Nicole Staab Cassis

    E-print Network

    Rhoads, James

    Geoscience exhibit displays `Trail of Time' By Nicole Staab Cassis Spectacular in its depth upon the canyon's potential for public geoscience educa- tion, scientists coordinated the construction of the world's largest geoscience interpretative exhibit: the Trail of Time. This interpretative walking time

  20. 14. Roaring Fork Motor Nature Trail, Place of a thousand ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Roaring Fork Motor Nature Trail, Place of a thousand drips, view with three culvert pipes. - Great Smoky Mountains National Park Roads & Bridges, Roaring Fork Motor Nature Trail, Between Cherokee Orchard Road & U.S. Route 321, Gatlinburg, Sevier County, TN

  1. View of blind curve along National Old Trails Road, about ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of blind curve along National Old Trails Road, about 1,000 feet from top, facing north. - La Bajada Historic Trails and Roads, Approximately 1 mile East/Northeast of intersection of State Highway 16 and Indian Service Road 841, La Bajada, Santa Fe County, NM

  2. On the Trail of Drug-Defying Superbugs

    MedlinePLUS

    ... the Trail of Drug-Defying Superbugs Inside Life Science View All Articles | Inside Life Science Home Page On the Trail of Drug-Defying ... Findings About Our Resident Microbes This Inside Life Science article also appears on LiveScience . Learn about related ...

  3. Will human recreational activity on levee trails enhance carnivore activity?

    E-print Network

    Johnson, Matthew

    Will human recreational activity on levee trails enhance carnivore activity? Will human recreational activity on levee trails enhance carnivore activity? INTRODUCTION For people and terrestrial 2006, we conducted carnivore surveys in control and impact areas established along the levee (Figure 1

  4. Discussion on "The Trail" from the Perspective of Christianism Theology

    ERIC Educational Resources Information Center

    Wang, Jing

    2008-01-01

    Kafka is a writer of strong religious complex. In "The Trail," he illustrates his religious thoughts by probing into the alienation of modern human beings from the God and also shows his pursuit and befuddlement of beliefs. This paper analyzes the crimes and punishment in "The Trail" through three parts, the accusation of…

  5. Rail Trails and Property Values: Is There an Association?

    ERIC Educational Resources Information Center

    Hartenian, Ella; Horton, Nicholas J.

    2015-01-01

    The Rail Trail and Property Values dataset includes information on a set of n = 104 homes which sold in Northampton, Massachusetts in 2007. The dataset provides house information (square footage, acreage, number of bedrooms, etc.), price estimates (from Zillow.com) at four time points, location, distance from a rail trail in the community, biking…

  6. Hydrodynamic Trails Produced by Daphnia: Size and Energetics

    PubMed Central

    Wickramarathna, Lalith N.; Noss, Christian; Lorke, Andreas

    2014-01-01

    This study focuses on quantifying hydrodynamic trails produced by freely swimming zooplankton. We combined volumetric tracking of swimming trajectories with planar observations of the flow field induced by Daphnia of different size and swimming in different patterns. Spatial extension of the planar flow field along the trajectories was used to interrogate the dimensions (length and volume) and energetics (dissipation rate of kinetic energy and total dissipated power) of the trails. Our findings demonstrate that neither swimming pattern nor size of the organisms affect the trail width or the dissipation rate. However, we found that the trail volume increases with increasing organism size and swimming velocity, more precisely the trail volume is proportional to the third power of Reynolds number. This increase furthermore results in significantly enhanced total dissipated power at higher Reynolds number. The biggest trail volume observed corresponds to about 500 times the body volume of the largest daphnids. Trail-averaged viscous dissipation rate of the swimming daphnids vary in the range of to and the observed magnitudes of total dissipated power between and , respectively. Among other zooplankton species, daphnids display the highest total dissipated power in their trails. These findings are discussed in the context of fluid mixing and transport by organisms swimming at intermediate Reynolds numbers. PMID:24671019

  7. Trailing edge flow conditions as a factor in airfoil design

    NASA Technical Reports Server (NTRS)

    Ormsbee, A. I.; Maughmer, M. D.

    1984-01-01

    Some new developments relevant to the design of single-element airfoils using potential flow methods are presented. In particular, the role played by the non-dimensional trailing edge velocity in design is considered and the relationship between the specified value and the resulting airfoil geometry is explored. In addition, the ramifications of the unbounded trailing edge pressure gradients generally present in the potential flow solution of the flow over an airfoil are examined, and the conditions necessary to obtain a class of airfoils having finite trailing edge pressure gradients developed. The incorporation of these conditions into the inverse method of Eppler is presented and the modified scheme employed to generate a number of airfoils for consideration. The detailed viscous analysis of airfoils having finite trailing edge pressure gradients demonstrates a reduction in the strong inviscid-viscid interactions generally present near the trailing edge of an airfoil.

  8. Partially turbulated trailing edge cooling passages for gas turbine nozzles

    DOEpatents

    Thatcher, Jonathan Carl (Schenectady, NY); Burdgick, Steven Sebastian (Schenectady, NY)

    2001-01-01

    A plurality of passages are spaced one from the other along the length of a trailing edge of a nozzle vane in a gas turbine. The passages lie in communication with a cavity in the vane for flowing cooling air from the cavity through the passages through the tip of the trailing edge into the hot gas path. Each passage is partially turbulated and includes ribs in an aft portion thereof to provide enhanced cooling effects adjacent the tip of the trailing edge. The major portions of the passages are smooth bore. By this arrangement, reduced temperature gradients across the trailing edge metal are provided. Additionally, the inlets to each of the passages have a restriction whereby a reduced magnitude of compressor bleed discharge air is utilized for trailing edge cooling purposes.

  9. Fast and Flexible: Argentine Ants Recruit from Nearby Trails

    PubMed Central

    Flanagan, Tatiana P.; Pinter-Wollman, Noa M.; Moses, Melanie E.; Gordon, Deborah M.

    2013-01-01

    Argentine ants (Linepithema humile) live in groups of nests connected by trails to each other and to stable food sources. In a field study, we investigated whether some ants recruit directly from established, persistent trails to food sources, thus accelerating food collection. Our results indicate that Argentine ants recruit nestmates to food directly from persistent trails, and that the exponential increase in the arrival rate of ants at baits is faster than would be possible if recruited ants traveled from distant nests. Once ants find a new food source, they walk back and forth between the bait and sometimes share food by trophallaxis with nestmates on the trail. Recruiting ants from nearby persistent trails creates a dynamic circuit, like those found in other distributed systems, which facilitates a quick response to changes in available resources. PMID:23967129

  10. Evaluating a Negotiated Rulemaking Process at Cape Hatteras National Seashore: Toward Piping Plover and People in One Place 

    E-print Network

    Merritt, Lavell

    2011-02-22

    process to create an Off Road Vehicle Management Rule. The rulemaking process involved park stakeholders working with the NPS as a Negotiated Rulemaking Advisory Committee with the goal of creating an Off Road Vehicle Management Rule for CAHA...

  11. 43 CFR 420.3 - Adjacent lands.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...OF THE INTERIOR OFF-ROAD VEHICLE USE § 420.3 Adjacent lands. When administratively feasible, the regulation of off-road vehicle use on Reclamation lands will be compatible with such use as permitted by...

  12. Trail-following responses of the Argentine ant,Iridomyrmex humilis (Mayr), to a synthetic trail pheromone component and analogs.

    PubMed

    Van Vorhis Key, S E; Baker, T C

    1982-01-01

    Behavioral evidence indicates that (Z)-9-hexadecenal (Z9-16?ALD) is a trail pheromone component ofIridomyrmex humilis, and that the true trail pheromone may be multicomponent. Trail-following responses ofI. humilis workers to several concentrations of syntheticZ9-16?ALD, a constituent of the Pavan's gland, were found to be comparable to responses to gaster extract trails containing ca. 100 times lessZ9-16?ALD. Of the five aldehyde analogs tested, only (Z)-7-hexadecenal (Z7-16?ALD) elicited significant trail-following. However, following responses to severalZ9-16?ALD-Z7-16?ALD combinations were lower than responses toZ9-16?ALD alone. Trails on filter paper of biologically relevant concentrations ofZ9-16?ALD lose activity within 2 hr in the laboratory. The release rate ofZ9-16?ALD measured from filter paper trails was 0.25 ± 0.10 pg/cm-sec. This was used to estimate the trail-following threshold for this compound of Argentine ant workers. PMID:24414579

  13. Interior of shop, showing the reheat furnaces; the vehicle in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior of shop, showing the reheat furnaces; the vehicle in the center is a charging machine the operator of which manipulates steel ingots in the furnace, as well as in the adjacent forging hammers - Bethlehem Steel Corporation, South Bethlehem Works, Tool Steel-Electric Furnace Shop, Along Lehigh River, North of Fourth Street, West of Minsi Trail Bridge, Bethlehem, Northampton County, PA

  14. Wind turbine trailing edge aerodynamic brakes

    SciTech Connect

    Migliore, P G; Miller, L S; Quandt, G A

    1995-04-01

    Five trailing-edge devices were investigated to determine their potential as wind-turbine aerodynamic brakes, and for power modulation and load alleviation. Several promising configurations were identified. A new device, called the spoiler-flap, appears to be the best alternative. It is a simple device that is effective at all angles of attack. It is not structurally intrusive, and it has the potential for small actuating loads. It is shown that simultaneous achievement of a low lift/drag ratio and high drag is the determinant of device effectiveness, and that these attributes must persist up to an angle of attack of 45{degree}. It is also argued that aerodynamic brakes must be designed for a wind speed of at least 45 m/s (100 mph).

  15. Trailing Ballute Aerocapture: Concept and Feasibility Assessment

    NASA Technical Reports Server (NTRS)

    Miller, Kevin L.; Gulick, Doug; Lewis, Jake; Trochman, Bill; Stein, Jim; Lyons, Daniel T.; Wilmoth, Richard G.

    2003-01-01

    Trailing Ballute Aerocapture offers the potential to obtain orbit insertion around a planetary body at a fraction of the mass of traditional methods. This allows for lower costs for launch, faster flight times and additional mass available for science payloads. The technique involves an inflated ballute (balloon-parachute) that provides aerodynamic drag area for use in the atmosphere of a planetary body to provide for orbit insertion in a relatively benign heating environment. To account for atmospheric, navigation and other uncertainties, the ballute is oversized and detached once the desired velocity change (Delta V) has been achieved. Analysis and trades have been performed for the purpose of assessing the feasibility of the technique including aerophysics, material assessments, inflation system and deployment sequence and dynamics, configuration trades, ballute separation and trajectory analysis. Outlined is the technology development required for advancing the technique to a level that would allow it to be viable for use in space exploration missions.

  16. Development and evaluation of an in-vehicle information system

    SciTech Connect

    Spelt, P.F.; Tufano, D.R.; Knee, H.E.

    1997-04-01

    In this paper, the authors introduce an In-Vehicle Information System (IVIS) which will manage messages from a variety of Advanced Traveler Information Services (ATIS) devices which can be installed in a road vehicle. The IVIS serves as the interface between the driver and the driving information environment. Increasingly, aftermarket systems, such as routing and navigation aids, are becoming available which can be added to vehicles to aid in travel and/or the conduct of business in the vehicle. The installation of multiple devices, each with its own driver interface, increases the likelihood of driver distraction and thus the risk of an accident. The goal of this project is the development of a fully-integrated IVIS which will filter, prioritize and display highway and vehicle information safely and efficiently, while also providing an integrated driver interface to a variety of ATIS information sources. Because these devices will be integrated into IVIS as components, they are referred to in this paper as IVIS subsystems. Such a system, using modern digital technology, will tailor information both to the driver`s needs and to the driving environment. A variety of other efforts, both in the Us and abroad, either have been completed or are nearing completion, and the results of these efforts will be incorporated into this present system. IVIS must perform three high level functions (Tufano, et al, 1997). It must (1) interact with (ATIS) subsystems, (2) management information, and (3) interact with the driver. To safely develop and evaluate such a device, a platform must be devised which permits testing in an off-road setting.

  17. Active Management of Flap-Edge Trailing Vortices

    NASA Technical Reports Server (NTRS)

    Greenblatt, David; Yao, Chung-Sheng; Vey, Stefan; Paschereit, Oliver C.; Meyer, Robert

    2008-01-01

    The vortex hazard produced by large airliners and increasingly larger airliners entering service, combined with projected rapid increases in the demand for air transportation, is expected to act as a major impediment to increased air traffic capacity. Significant reduction in the vortex hazard is possible, however, by employing active vortex alleviation techniques that reduce the wake severity by dynamically modifying its vortex characteristics, providing that the techniques do not degrade performance or compromise safety and ride quality. With this as background, a series of experiments were performed, initially at NASA Langley Research Center and subsequently at the Berlin University of Technology in collaboration with the German Aerospace Center. The investigations demonstrated the basic mechanism for managing trailing vortices using retrofitted devices that are decoupled from conventional control surfaces. The basic premise for managing vortices advanced here is rooted in the erstwhile forgotten hypothesis of Albert Betz, as extended and verified ingeniously by Coleman duPont Donaldson and his collaborators. Using these devices, vortices may be perturbed at arbitrarily long wavelengths down to wavelengths less than a typical airliner wingspan and the oscillatory loads on the wings, and hence the vehicle, are small. Significant flexibility in the specific device has been demonstrated using local passive and active separation control as well as local circulation control via Gurney flaps. The method is now in a position to be tested in a wind tunnel with a longer test section on a scaled airliner configuration. Alternatively, the method can be tested directly in a towing tank, on a model aircraft, a light aircraft or a full-scale airliner. The authors believed that this method will have significant appeal from an industry perspective due to its retrofit potential with little to no impact on cruise (devices tucked away in the cove or retracted); low operating power requirements; small lift oscillations when deployed in a time-dependent manner; and significant flexibility with respect to the specific devices selected.

  18. Piperlongumine and immune cytokine TRAIL synergize to promote tumor death

    PubMed Central

    Li, Jiahe; Sharkey, Charles C.; King, Michael R.

    2015-01-01

    Malignant transformation results in increased levels of reactive oxygen species (ROS). Adaption to this toxic stress allows cancer cells to proliferate. Recently, piperlongumine (PL), a natural alkaloid, was identified to exhibit novel anticancer effects by targeting ROS signaling. PL induces apoptosis specifically in cancer cells by downregulating several anti-apoptotic proteins. Notably, the same anti-apoptotic proteins were previously found to reduce tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in cancer cells. Therefore, we reasoned that PL would synergize with TRAIL to stimulate potent apoptosis in cancer cells. We demonstrate for the first time that PL and TRAIL exhibit a synergistic anti-cancer effect in cancer cell lines of various origins. PL resulted in the upregulation of TRAIL receptor DR5, which potentiated TRAIL-induced apoptosis in cancer cells. Furthermore, such upregulation was found to be dependent on ROS and the activation of JNK and p38 kinases. Treatment with combined PL and TRAIL demonstrated significant anti-proliferative effects in a triple-negative breast cancer MDA-MB-231 xenograft model. This work provides a novel therapeutic approach for inducing cancer cell death. Combination of PL and TRAIL may suggest a novel paradigm for treatment of primary and metastatic tumors. PMID:25984950

  19. Quinacrine sensitizes hepatocellular carcinoma cells to TRAIL and chemotherapeutic agents.

    PubMed

    Wang, Wenge; Gallant, Jean-Nicolas; Katz, Sharyn I; Dolloff, Nathan G; Smith, Charles D; Abdulghani, Junaid; Allen, Joshua E; Dicker, David T; Hong, Bo; Navaraj, Arunasalam; El-Deiry, Wafik S

    2011-08-01

    Quinacrine has been widely explored in treatment of malaria, giardiasis, and rheumatic diseases. We find that quinacrine stabilizes p53 and induces p53-dependent and independent cell death. Treatment by quinacrine alone at concentrations of 10-20 mM for 1-2 d cannot kill hepatocellular carcinoma cells, such as HepG2, Hep3B, Huh7, which are also resistant to TRAIL. However, quinacrine renders these cells sensitive to treatment by TRAIL. Co-treatment of these cells with quinacrine and TRAIL induces overwhelming cell death within 3-4 h. Levels of DR5, a pro-apoptotic death receptor of TRAIL, are increased upon treatment with quinacrine, while levels of Mcl-1, an anti-apoptotic member of the Bcl-2 family, are decreased. While the synergistic effect of quinacrine with TRAIL appears to be in part independent of p53, knockdown of p53 in HepG2 cells by siRNA results in more cell death after treatment by quinacrine and TRAIL. The mechanism by which quinacrine sensitizes hepatocellular carcinoma cells to TRAIL and chemotherapies, and the potential for clinical application currently are being further explored. Lastly, quinacrine synergizes with chemotherapeutics, such as adriamycin, 5-FU, etoposide, CPT11, sorafenib, and gemcitabine, in killing hepatocellular carcinoma cells in vitro and the drug enhances the activity of sorafenib to delay tumor growth in vivo. PMID:21725212

  20. Xerox trails: a new web-based publishing technology

    NASA Astrophysics Data System (ADS)

    Rao, Venkatesh G.; Vandervort, David; Silverstein, Jesse

    2010-02-01

    Xerox Trails is a new digital publishing model developed at the Xerox Research Center, Webster. The primary purpose of the technology is to allow Web users and publishers to collect, organize and present information in the form of a useful annotated narrative (possibly non-sequential) with editorial content and metadata, that can be consumed both online and offline. The core concept is a trail: a digital object that improves online content production, consumption and navigation user experiences. When appropriate, trails can also be easily sequenced and transformed into printable documents, thereby bridging the gap between online and offline content experiences. The model is partly inspired by Vannevar Bush's influential idea of the "Memex" [1] which has inspired several generations of Web technology [2]. Xerox Trails is a realization of selected elements from the idea of the Memex, along with several original design ideas. It is based on a primitive data construct, the trail. In Xerox Trails, the idea of a trail is used to support the architecture of a Web 2.0 product suite called Trailmeme, that includes a destination Web site, plugins for major content management systems, and a browser toolbar.

  1. Aerodynamic Analysis of Trailing Edge Enlarged Wind Turbine Airfoils

    NASA Astrophysics Data System (ADS)

    Xu, Haoran; Shen, Wenzhong; Zhu, Weijun; Yang, Hua; Liu, Chao

    2014-06-01

    The aerodynamic performance of blunt trailing edge airfoils generated from the DU- 91-W2-250, DU-97-W-300 and DU-96-W-350 airfoils by enlarging the thickness of trailing edge symmetrically from the location of maximum thickness to chord to the trailing edge were analyzed by using CFD and RFOIL methods at a chord Reynolds number of 3 × 106. The goal of this study is to analyze the aerodynamic performance of blunt trailing edge airfoils with different thicknesses of trailing edge and maximum thicknesses to chord. The steady results calculated by the fully turbulent k-? SST, transitional k-? SST model and RFOIL all show that with the increase of thickness of trailing edge, the linear region of lift is extended and the maximum lift also increases, the increase rate and amount of lift become limited gradually at low angles of attack, while the drag increases dramatically. For thicker airfoils with larger maximum thickness to chord length, the increment of lift is larger than that of relatively thinner airfoils when the thickness of blunt trailing edge is increased from 5% to 10% chord length. But too large lift can cause abrupt stall which is profitless for power output. The transient characteristics of blunt trailing edge airfoils are caused by blunt body vortices at low angles of attack, and by the combined effect of separation and blunt body vortices at large angles of attack. With the increase of thickness of blunt trailing edge, the vibration amplitudes of lift and drag curves increase. The transient calculations over-predict the lift at large angles of attack and drag at all angles of attack than the steady calculations which is likely to be caused by the artificial restriction of the flow in two dimensions.

  2. Polarization and scattering of a long-duration meteor trail

    NASA Astrophysics Data System (ADS)

    Close, S.; Kelley, M.; Vertatschitsch, L.; Colestock, P.; Oppenheim, M.; Yee, J.

    2011-01-01

    High-power, large-aperture (HPLA) radars have been used over the past two decades to characterize the plasmas formed both around and behind meteoroids as they enter Earth's atmosphere. These plasmas, referred to as heads and trails, respectively, occur with relative frequency (peak head echo detection rate of ˜1/s) but are extremely diverse and have been difficult to define in a general sense. One particular type of plasma, referred to as the nonspecular trail, occurs when the meteoroid travels quasi-parallel to the radar beam with the radar beam lying quasi-perpendicular to the background magnetic field. Reflection is believed to occur from field-aligned irregularities (FAIs) that form after the trail becomes unstable. While FAI scattering pertains to the majority of nonspecular trails that are short in duration, a subset of these trails, referred to as long-duration trails, still remains open to interpretation. In this paper we present a case study analysis of a long-duration, nonspecular trail and its associated head echo detected with the Advanced Research Project Agency (ARPA) Long-Range Tracking and Identification Radar (ALTAIR), which is an HPLA radar. These data are unique in that they are high resolution (with monopulse angles), dual frequency, and, most importantly, dual polarized, which allows for unprecedented insight into the scattering process from both heads and trails. First, we determine the velocity and mass of the parent meteoroid, which is a particle weighing more than a milligram and is one of the largest meteoroids ever detected by ALTAIR. Second, we determine the peak plasma density and polarization of the head echo and characterize the unique, yet strong returns in the opposite polarization, which may be due to multiple scattering centers within the range gate. Finally, we examine the polarization properties of the trail and discuss the first conclusive evidence of polarization flipping along the trail striations, which we believe corresponds to sharp gradients at the edges of the trail related to turbulent mixing of a dusty plasma that is elongating along the magnetic field. We look into a new idea, namely, the notion that some nonspecular echoes might correspond to a high Schmidt number, dusty plasma, as is found in and above noctilucent clouds. Our results show how polarized return can aid in scattering diagnostics and that single polarization radars must be used with caution for determining head and trail plasma densities given that some of the return can occur in the “unexpected” channel.

  3. 78 FR 59368 - Notice of Joint Meeting for Captain John Smith Chesapeake National Historic Trail Advisory...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ... Advisory Council and Star-Spangled Banner National Historic Trail Advisory Council AGENCY: National Park... John Smith Chesapeake National Historic Trail and the Star-Spangled Banner National Historic Trail will.... The Star-Spangled Banner National Historic Trail consists of ``water and overland routes...

  4. 77 FR 25910 - National Trails System Act and Railroad Rights-of-Way

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-02

    .... \\1\\ The notice of proposed rulemaking was published at 76 FR 8992-95. Background. The Trails Act was... Surface Transportation Board 49 CFR Part 1152 National Trails System Act and Railroad Rights-of-Way AGENCY... Trails System Act (Trails Act). New rules are adopted that require the parties jointly to notify...

  5. 78 FR 59368 - Notice of Joint Meeting for Captain John Smith Chesapeake National Historic Trail Advisory...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ...National Historic Trail Advisory Council and Star-Spangled Banner National Historic Trail...Chesapeake National Historic Trail and the Star-Spangled Banner National Historic Trail...and waterways of the Chesapeake Bay. The Star-Spangled Banner National Historic...

  6. 76 FR 8992 - National Trails System Act and Railroad Rights-of-Way

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-16

    ...Docket No. EP 702] National Trails System Act and...Board) has instituted a proceeding to clarify, update...trail use under the National Trails System Act...Board is instituting a proceeding to clarify, update...Section 8(d) of the National Trails System...

  7. Indicators and protocols for monitoring impacts of formal and informal trails in protected areas

    USGS Publications Warehouse

    Marion, Jeffrey L.; Leung, Yu-Fai

    2011-01-01

    Trails are a common recreation infrastructure in protected areas and their conditions affect the quality of natural resources and visitor experiences. Various trail impact indicators and assessment protocols have been developed in support of monitoring programs, which are often used for management decision-making or as part of visitor capacity management frameworks. This paper reviews common indicators and assessment protocols for three types of trails, surfaced formal trails, unsurfaced formal trails, and informal (visitor-created) trails. Monitoring methods and selected data from three U.S. National Park Service units are presented to illustrate some common trail impact indicators and assessment options.

  8. 30 CFR 56.12003 - Trailing cable overload protection.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Electricity § 56.12003 Trailing cable overload protection. Individual overload protection or short circuit protection shall...

  9. 30 CFR 57.12088 - Splicing trailing cables.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Electricity Underground Only § 57.12088 Splicing trailing cables. No splice, except a vulcanized splice or its...

  10. 30 CFR 57.12003 - Trailing cable overload protection.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Electricity Surface and Underground § 57.12003 Trailing cable overload protection. Individual overload protection or...

  11. 30 CFR 57.12088 - Splicing trailing cables.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Electricity Underground Only § 57.12088 Splicing trailing cables. No splice, except a vulcanized splice or its...

  12. 30 CFR 56.12003 - Trailing cable overload protection.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Electricity § 56.12003 Trailing cable overload protection. Individual overload protection or short circuit protection shall...

  13. 30 CFR 57.12088 - Splicing trailing cables.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Electricity Underground Only § 57.12088 Splicing trailing cables. No splice, except a vulcanized splice or its...

  14. 30 CFR 56.12003 - Trailing cable overload protection.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Electricity § 56.12003 Trailing cable overload protection. Individual overload protection or short circuit protection shall...

  15. 30 CFR 57.12088 - Splicing trailing cables.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Electricity Underground Only § 57.12088 Splicing trailing cables. No splice, except a vulcanized splice or its...

  16. Unsolved Mystery Visual Trails: Do the Doors of Perception Open

    E-print Network

    Van Rullen, Rufin

    is a report of illegal marijuana leading to trailing by Levi and Miller [27], in which they explicitly acknowledge that their cases may be confounded by the presence of impurities in illegal marijuana, as well

  17. 36 CFR 261.55 - National Forest System trails.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false National Forest System trails. 261.55 Section 261.55 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE...

  18. 36 CFR 261.55 - National Forest System trails.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false National Forest System trails. 261.55 Section 261.55 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE...

  19. 36 CFR 261.55 - National Forest System trails.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false National Forest System trails. 261.55 Section 261.55 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE...

  20. 36 CFR 261.55 - National Forest System trails.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false National Forest System trails. 261.55 Section 261.55 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE...

  1. 36 CFR 261.55 - National Forest System trails.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false National Forest System trails. 261.55 Section 261.55 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE...

  2. Analyzing audit trails in the Aeolus security platform

    E-print Network

    Blankstein, Aaron (Aaron M.)

    2011-01-01

    This thesis presents the design and implementation of an analysis system for audit trails generated by Aeolus, a distributed security platform based on information flow control. Previous work focused on collecting these ...

  3. Audit Trails in the Aeolus Distributed Security Platform

    E-print Network

    Popic, Victoria

    2010-09-29

    This thesis provides a complete design and implementation of audit trail collection and storage for Aeolus, a distributed security platform based on information flow control. An information flow control system regulates ...

  4. Audit trails in the Aeolus distributed security platform

    E-print Network

    Popic, Victoria

    2010-01-01

    This thesis provides a complete design and implementation of audit trail collection and storage for Aeolus, a distributed security platform based on information flow control. An information flow control system regulates ...

  5. The Best Trail Algorithm for Assisted Navigation of Web Sites

    E-print Network

    Levene, Mark

    the information they are looking for [23]. Vannevar Bush envisaged a hypothetical machine called a memex [9 could then be annotated and linked together to form a trail. By continuing the process, Bush imagined

  6. 30 CFR 75.827 - Guarding of trailing cables.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...High-Voltage Distribution High-Voltage Longwalls § 75.827 Guarding of trailing cables. (a) Guarding. (1) The high-voltage cable must be guarded in the following...locations: (i) From the power center cable coupler...

  7. Road to Victory: Building the Ho Chi Minh Trail.

    ERIC Educational Resources Information Center

    Kenney, Marianne

    1993-01-01

    Presents a secondary school lesson on the building of the Ho Chi Minh Trail during the Vietnam War. Helps students link history and geographical skills through cooperative group learning. Includes maps, diagrams, and three student readings. (CFR)

  8. Regulation of TRAIL-Receptor Expression by the Ubiquitin-Proteasome System

    PubMed Central

    Sarhan, Dhifaf; D’Arcy, Padraig; Lundqvist, Andreas

    2014-01-01

    The tumor necrosis factor (TNF)-related apoptosis-inducing ligand- receptor (TRAIL-R) family has emerged as a key mediator of cell fate and survival. Ligation of TRAIL ligand to TRAIL-R1 or TRAIL-R2 initiates the extrinsic apoptotic pathway characterized by the recruitment of death domains, assembly of the death-inducing signaling complex (DISC), caspase activation and ultimately apoptosis. Conversely the decoy receptors TRAIL-R3 and TRAIL-R4, which lack the pro-apoptotic death domain, function to dampen the apoptotic response by competing for TRAIL ligand. The tissue restricted expression of the decoy receptors on normal but not cancer cells provides a therapeutic rational for the development of selective TRAIL-mediated anti-tumor therapies. Recent clinical trials using agonistic antibodies against the apoptosis-inducing TRAIL receptors or recombinant TRAIL have been promising; however the number of patients in complete remission remains stubbornly low. The mechanisms of TRAIL resistance are relatively unexplored but may in part be due to TRAIL-R down-regulation or shedding of TRAIL-R by tumor cells. Therefore a better understanding of the mechanisms underlying TRAIL resistance is required. The ubiquitin-proteasome system (UPS) has been shown to regulate TRAIL-R members suggesting that pharmacological inhibition of the UPS may be a novel strategy to augment TRAIL-based therapies and increase efficacies. We recently identified b-AP15 as an inhibitor of proteasome deubiquitinase (DUB) activity. Interestingly, exposure of tumor cell lines to b-AP15 resulted in increased TRAIL-R2 expression and enhanced sensitivity to TRAIL-mediated apoptosis and cell death in vitro and in vivo. In conclusion, targeting the UPS may represent a novel strategy to increase the cell surface expression of pro-apoptotic TRAIL-R on cancer cells and should be considered in clinical trials targeting TRAIL-receptors in cancer patients. PMID:25318057

  9. The Shape Trail Test: Application of a New Variant of the Trail Making Test

    PubMed Central

    Zhao, Qianhua; Guo, Qihao; Li, Fang; Zhou, Yan; Wang, Bei; Hong, Zhen

    2013-01-01

    Objective The Trail making test (TMT) is culture-loaded because of reliance on the Latin alphabet, limiting its application in Eastern populations. The Shape Trail Test (STT) has been developed as a new variant. This study is to examine the applicability of the STT in a senile Chinese population and to evaluate its potential advantages and disadvantages. Method A total of 2470 participants were recruited, including 1151 cognitively normal control (NC), 898 amnestic mild cognitive impairment (aMCI), and 421 mild Alzheimer disease (AD) patients. Besides the STT, the Mini mental state examination and a comprehensive neuropsychological battery involving memory, language, attention, executive function and visuospatial ability were administered to all the participants. In a subgroup of 100 NC and 50 AD patients, both the STT and the Color Trail Test (CTT) were performed. Results In NC, the time consumed for Part A and B (STT-A and STT-B) significantly correlated with age and negatively correlated with education (p<0.01). STT-A and B significantly differed among the AD, aMCI and NC. The number that successfully connected within one minute in Part B (STT-B-1 min) correlated well with STT-B (r?=?0.71, p<0.01) and distinguished well among NC, aMCI and AD. In the receiver operating characteristic curve analysis, the AUCs (area under the curve) for STT-A, STT-B, and STT-B-1min in identifying AD were 0.698, 0.694 and 0.709, respectively. The STT correlated with the CTT, but the time for completion was longer. Conclusion The TMT is a sensitive test of visual search and sequencing. The STT is a meaningful attempt to develop a “culture-fair” variant of the TMT in addition to the CTT. PMID:23437370

  10. Modelling landscape-scale erosion potential related to vehicle disturbances along the U.S.-Mexico border

    USGS Publications Warehouse

    Villarreal, Miguel; Webb, Robert H.; Norman, Laura M.; Psillas, Jennifer L.; Rosenberg, Abigail S.; Carmichael, Shinji; Petrakis, Roy E.; Sparks, Philip E.

    2014-01-01

    Decades of intensive off-road vehicle use for border security, immigration, smuggling, recreation, and military training along the United States-Mexico border has prompted concerns about long-term human impacts on sensitive desert ecosystems. To help managers identify areas susceptible to soil erosion from anthropogenic activities, we developed a series of erosion potential models based on factors from the Universal Soil Loss Equation (USLE). To better express the vulnerability of soils to human disturbances, we refined two factors whose categorical and spatial representations limit the application of the USLE for non-agricultural landscapes: the C-factor (vegetation cover) and the P-factor (support practice/management). A soil compaction index (P-factor) was calculated as the difference in saturated hydrologic conductivity (Ks) between disturbed and undisturbed soils, which was then scaled up to maps of vehicle disturbances digitized from aerial photography. The C-factor was improved using a satellite-based vegetation index, which was better correlated with estimated ground cover (r2?=?0.77) than data derived from land cover (r2?=?0.06). We identified 9,780?km of unauthorized off-road tracks in the 2,800?km2 study area. Maps of these disturbances, when integrated with soil compaction data using the USLE, provided landscape-scale information on areas vulnerable to erosion from both natural processes and human activities, and are detailed enough for adaptive management and restoration planning. The models revealed erosion potential hotspots adjacent to the border and within areas managed as critical habitat for the threatened flat-tailed horned lizard and endangered Sonoran Pronghorn.

  11. Osteoprotegerin and TRAIL in Acute Onset of Atrial Fibrillation

    PubMed Central

    Rewiuk, Krzysztof; Grodzicki, Tomasz

    2015-01-01

    Background. There is a growing amount of evidence that inflammatory processes are involved in the development of atrial fibrillation (AF) and its complications. We decided to investigate the behavior of osteoprotegerin (OPG) and TNF-related apoptosis inducing ligand (TRAIL) in terms of acute onset of AF. Methods and Results. We included 60 patients with acute onset of AF, candidates for pharmacological cardioversion. The presence of cardiovascular comorbidities was connected with higher concentration of OPG and lower level of TRAIL right from the first hours of AF paroxysm. The initial TRAIL level correlated also positively with left ventricle ejection fraction and negatively with left atrium diameter. We found subsequent increase of OPG in subgroups selected on the basis of CHA2DS2-VASc scoring. Although basal concentrations of studied markers did not allow prediction of the restoration of sinus rhythm, we observed important increase of TRAIL concentration in subgroup with sinus rhythm maintenance (94.11 ± 29.46 versus 111.39 ± 30.23?pg/mL; p = 0.002). Conclusions. OPG and TRAIL are associated with the underlying cardiovascular damage in AF, but their balance is modulated by the fact of sinus rhythm restoration. Determining the suitability of OPG and TRAIL as predictive markers in AF requires further prospective studies. PMID:26504794

  12. Trail marking by larvae of the cactus moth, Cactoblastis cactorum.

    PubMed

    Fitzgerald, Terrence D; Wolfin, Michael; Rossi, Frank; Carpenter, James E; Pescador-Rubio, Alfonso

    2014-01-01

    The cactus moth, Cactoblastis cactorum (Berg) (Lepidoptera: Pyralidae), spends most of its larval life feeding within the cladodes of Opuntia cactuses, but the gregarious caterpillars begin their life outside the plant, and in the later instars make intermittent excursions over plant surfaces to access new cladodes and to thermoregulate. The study reported here showed that when the caterpillars move en masse, they mark and follow trails that serve to keep the cohort together. Artificial trails prepared from hexane extracts of the caterpillar's paired mandibular glands were readily followed by the caterpillars. The glands are remarkably large, and their fluid contents, which constitute approximately 1% of the total wet mass of a caterpillar, are secreted onto the substrate as they move. Although the caterpillars also lay down copious quantities of silk, the material in itself neither elicits trail following nor is it a requisite component of pathways that elicit trail following. Previous analyses of the mandibular glands of other species of pyralid caterpillars showed that they contain a series of structurally distinct 2-acyl-1,3 cyclohexane diones. Chemical analysis indicates that the glands of C. cactorum contain structurally similar compounds, and bio- assays indicate that trail following occurs in response to these chemicals. While the mandibular glands' fluids have been shown to act as semiochemicals, effecting both interspecific and intra- specific behavior in other species of pyralids, the present study is the first to report their use as a trail pheromone. PMID:25373211

  13. Trail Marking by Larvae of the Cactus Moth, Cactoblastis cactorum

    PubMed Central

    Fitzgerald, Terrence D.; Wolfin, Michael; Rossi, Frank; Carpenter, James E.; Pescador-Rubio, Alfonso

    2014-01-01

    The cactus moth, Cactoblastis cactorum (Berg) (Lepidoptera: Pyralidae), spends most of its larval life feeding within the cladodes of Opuntia cactuses, but the gregarious caterpillars begin their life outside the plant, and in the later instars make intermittent excursions over plant surfaces to access new cladodes and to thermoregulate. The study reported here showed that when the caterpillars move en masse, they mark and follow trails that serve to keep the cohort together. Artificial trails prepared from hexane extracts of the caterpillar's paired mandibular glands were readily followed by the caterpillars. The glands are remarkably large, and their fluid contents, which constitute approximately 1% of the total wet mass of a caterpillar, are secreted onto the substrate as they move. Although the caterpillars also lay down copious quantities of silk, the material in itself neither elicits trail following nor is it a requisite component of pathways that elicit trail following. Previous analyses of the mandibular glands of other species of pyralid caterpillars showed that they contain a series of structurally distinct 2-acyl-1,3 cyclohexane diones. Chemical analysis indicates that the glands of C. cactorum contain structurally similar compounds, and bioassays indicate that trail following occurs in response to these chemicals. While the mandibular glands' fluids have been shown to act as semiochemicals, effecting both interspecific and intraspecific behavior in other species of pyralids, the present study is the first to report their use as a trail pheromone. PMID:25373211

  14. VisTrails : enabling interactive multiple-view visualizations.

    SciTech Connect

    Scheidegger, Carlos E.; Vo, Huy T.; Crossno, Patricia Joyce; Callahan, Steven P.; Bavoil, Louis; Freire, Juliana.; Silva, Claudio

    2005-04-01

    VisTrails is a new system that enables interactive multiple-view visualizations by simplifying the creation and maintenance of visualization pipelines, and by optimizing their execution. It provides a general infrastructure that can be combined with existing visualization systems and libraries. A key component of VisTrails is the visualization trail (vistrail), a formal specification of a pipeline. Unlike existing dataflow-based systems, in VisTrails there is a clear separation between the specification of a pipeline and its execution instances. This separation enables powerful scripting capabilities and provides a scalable mechanism for generating a large number of visualizations. VisTrails also leverages the vistrail specification to identify and avoid redundant operations. This optimization is especially useful while exploring multiple visualizations. When variations of the same pipeline need to be executed, substantial speedups can be obtained by caching the results of overlapping subsequences of the pipelines. In this paper, we describe the design and implementation of VisTrails, and show its effectiveness in different application scenarios.

  15. Europa's Northern Trailing Hemisphere: Lineament Stratigraphic Framework

    NASA Technical Reports Server (NTRS)

    Figueredo, P. H.; Hare, T.; Ricq, E.; Strom, K.; Greeley, R.; Tanaka, K.; Senske, D.

    2004-01-01

    Knowledge of the global distribution of Europan geologic units in time and space is a necessary step for the synthesis of the results of the Galileo mission and in preparation for future exploration (namely, by JIMO) of the satellite. We have initiated the production of the first Global Geological Map of Europa. As a base map, we use the recently published global photomosaic of Europa (U.S.G.S. Map I-2757) and additional Galileo SSI images at their original resolution. The map is being produced entirely on GIS format for analysis and combination with other datasets [1]. One of the main objectives of this project is to establish a global stratigraphic framework for Europa. In the absence of a well-developed cratering record, this goal will be achieved using the satellite s global network of lineaments (ridges, ridge complexes and bands; cf. [2]). Here we present the preliminary stratigraphic framework synthesized from the sequence of lineaments derived for the northern trailing hemisphere of Europa (Figure 1, below), and we discuss its significance and some emerging implications.

  16. Sesquiterpenes with TRAIL-resistance overcoming activity from Xanthium strumarium.

    PubMed

    Karmakar, Utpal K; Ishikawa, Naoki; Toume, Kazufumi; Arai, Midori A; Sadhu, Samir K; Ahmed, Firoj; Ishibashi, Masami

    2015-08-01

    The ability of TRAIL to selectively induce apoptosis in cancer cells while sparing normal cells makes it an attractive target for the development of new cancer therapy. In search of bioactive natural products for overcoming TRAIL-resistance from natural resources, we previously reported a number of active compounds. In our screening program on natural resources targeting overcoming TRAIL-resistance, activity-guided fractionations of the extract of Xanthium strumarium led to the isolation of five sesquiterpene compounds (1-5). 11?,13-dihydroxanthinin (2) and 11?,13-dihydroxanthuminol (3) were first isolated from natural resources and xanthinosin (1), desacetylxanthanol (4), and lasidiol p-methoxybenzoate (5) were known compounds. All compounds (1-5) showed potent TRAIL-resistance overcoming activity at 8, 20, 20, 16, and 16 ?M, respectively, in TRAIL-resistant AGS cells. Compounds 1 and 5 enhanced the levels of apoptosis inducing proteins DR4, DR5, p53, CHOP, Bax, cleaved caspase-3, cleaved caspase-8, and cleaved caspase-9 and also decreased the levels of cell survival protein Bcl-2 in TRAIL-resistant AGS cells in a dose-dependent manner. Compound 1 also enhanced the levels of DR4 and DR5 proteins in a time-dependent manner. Thus, compounds 1 and 5 were found to induce both extrinsic and intrinsic apoptotic cell death. Compound 1 also exhibit TRAIL-resistance overcoming activity in DLD1, DU145, HeLa, and MCF7 cells but did not decrease viability in non-cancer HEK293 cells up to 8 ?M. PMID:26081757

  17. Using certification trails to achieve software fault tolerance

    NASA Technical Reports Server (NTRS)

    Sullivan, Gregory F.; Masson, Gerald M.

    1993-01-01

    A conceptually novel and powerful technique to achieve fault tolerance in hardware and software systems is introduced. When used for software fault tolerance, this new technique uses time and software redundancy and can be outlined as follows. In the initial phase, a program is run to solve a problem and store the result. In addition, this program leaves behind a trail of data called a certification trail. In the second phase, another program is run which solves the original problem again. This program, however, has access to the certification trail left by the first program. Because of the availability of the certification trail, the second phase can be performed by a less complex program and can execute more quickly. In the final phase, the two results are accepted as correct; otherwise an error is indicated. An essential aspect of this approach is that the second program must always generate either an error indication or a correct output even when the certification trail it receives from the first program is incorrect. The certification trail approach to fault tolerance was formalized and it was illustrated by applying it to the fundamental problem of finding a minimum spanning tree. Cases in which the second phase can be run concorrectly with the first and act as a monitor are discussed. The certification trail approach was compared to other approaches to fault tolerance. Because of space limitations we have omitted examples of our technique applied to the Huffman tree, and convex hull problems. These can be found in the full version of this paper.

  18. Experimental evaluation of the certification-trail method

    NASA Technical Reports Server (NTRS)

    Sullivan, Gregory F.; Wilson, Dwight S.; Masson, Gerald M.; Itoh, Mamoru; Smith, Warren W.; Kay, Jonathan S.

    1993-01-01

    Certification trails are a recently introduced and promising approach to fault-detection and fault-tolerance. A comprehensive attempt to assess experimentally the performance and overall value of the method is reported. The method is applied to algorithms for the following problems: huffman tree, shortest path, minimum spanning tree, sorting, and convex hull. Our results reveal many cases in which an approach using certification-trails allows for significantly faster overall program execution time than a basic time redundancy-approach. Algorithms for the answer-validation problem for abstract data types were also examined. This kind of problem provides a basis for applying the certification-trail method to wide classes of algorithms. Answer-validation solutions for two types of priority queues were implemented and analyzed. In both cases, the algorithm which performs answer-validation is substantially faster than the original algorithm for computing the answer. Next, a probabilistic model and analysis which enables comparison between the certification-trail method and the time-redundancy approach were presented. The analysis reveals some substantial and sometimes surprising advantages for ther certification-trail method. Finally, the work our group performed on the design and implementation of fault injection testbeds for experimental analysis of the certification trail technique is discussed. This work employs two distinct methodologies, software fault injection (modification of instruction, data, and stack segments of programs on a Sun Sparcstation ELC and on an IBM 386 PC) and hardware fault injection (control, address, and data lines of a Motorola MC68000-based target system pulsed at logical zero/one values). Our results indicate the viability of the certification trail technique. It is also believed that the tools developed provide a solid base for additional exploration.

  19. Msi1 confers resistance to TRAIL by activating ERK in liver cancer cells.

    PubMed

    Liu, Nianli; Chen, Tianran; Wang, Xiaohong; Yang, Darong; Xue, Binbin; Zhu, Haizhen

    2015-04-01

    To investigate TRAIL resistance mechanisms in hepatocellular carcinoma (HCC), we isolated a stable TRAIL-resistant sub-population of the HCC cell line LH86, designated LH86-TR. Differential activation of AKT was not responsible for acquisition of TRAIL resistance. Cells with both congenital and acquired resistance to TRAIL exhibited increased Msi1 expression, which conferred TRAIL resistance by activating ERK. Forced expression of Msi1 decreased the sensitivity of HCC cells to TRAIL both in vitro and in vivo. Conversely, shRNA-mediated depletion of Msi1 enhanced TRAIL efficacy. SiRNA-mediated depletion of ERK overcame TRAIL resistance. Hence, we conclude that Msi1 is a mediator of TRAIL resistance in HCC cells. PMID:25747387

  20. Status report on next-generation LADAR for driving unmanned ground vehicles

    NASA Astrophysics Data System (ADS)

    Juberts, Maris; Barbera, Anthony J.

    2004-12-01

    The U.S. Department of Defense has initiated plans for the deployment of autonomous robotic vehicles in various tactical military operations starting in about seven years. Most of these missions will require the vehicles to drive autonomously over open terrain and on roads which may contain traffic, obstacles, military personnel as well as pedestrians. Unmanned Ground Vehicles (UGVs) must therefore be able to detect, recognize and track objects and terrain features in very cluttered environments. Although several LADAR sensors exist today which have successfully been implemented and demonstrated to provide somewhat reliable obstacle detection and can be used for path planning and selection, they tend to be limited in performance, are effected by obscurants, and are quite large and expensive. In addition, even though considerable effort and funding has been provided by the DOD R&D community, nearly all of the development has been for target detection (ATR) and tracking from various flying platforms. Participation in the Army and DARPA sponsored UGV programs has helped NIST to identify requirement specifications for LADAR to be used for on and off-road autonomous driving. This paper describes the expected requirements for a next generation LADAR for driving UGVs and presents an overview of proposed LADAR design concepts and a status report on current developments in scannerless Focal Plane Array (FPA) LADAR and advanced scanning LADAR which may be able to achieve the stated requirements. Examples of real-time range images taken with existing LADAR prototypes will be presented.

  1. Trails Management at LANL - A Presentation to the Los Alamos County Parks and Recreation Board

    SciTech Connect

    Pava, Daniel Seth

    2015-05-12

    Los Alamos National Laboratory’s (LANL) trail management program goals include reduce risk of damage and injury to property, human life, and health, and sensitive natural and cultural resources from social trail use at LANL, facilitate the establishment of a safe viable network of linked trails, maintain security of LANL operations, and many more, respect the wishes of local Pueblos, adapt trail use to changing conditions in a responsive manner, and maintain the recreational functionality of the DOE lands. There are approximately 30 miles of LANL trails. Some are open to the public and allow bicycles, horses, hikers, and runners. Know the rules of the trails to stay safe.

  2. Leading and Trailing Anvil Clouds of West African Squall Lines

    NASA Technical Reports Server (NTRS)

    Centrone, Jasmine; Houze, Robert A.

    2011-01-01

    The anvil clouds of tropical squall-line systems over West Africa have been examined using cloud radar data and divided into those that appear ahead of the leading convective line and those on the trailing side of the system. The leading anvils are generally higher in altitude than the trailing anvil, likely because the hydrometeors in the leading anvil are directly connected to the convective updraft, while the trailing anvil generally extends out of the lower-topped stratiform precipitation region. When the anvils are subdivided into thick, medium, and thin portions, the thick leading anvil is seen to have systematically higher reflectivity than the thick trailing anvil, suggesting that the leading anvil contains numerous larger ice particles owing to its direct connection to the convective region. As the leading anvil ages and thins, it retains its top. The leading anvil appears to add hydrometeors at the highest altitudes, while the trailing anvil is able to moisten a deep layer of the atmosphere.

  3. The Dust Trail of Comet 67P/Churyumov-Gerasimenko

    E-print Network

    Michael S. Kelley; William T. Reach; David J. Lien

    2007-09-06

    We report the detection of comet 67P/Churyumov-Gerasimenko's dust trail and nucleus in 24 micron Spitzer Space Telescope images taken February 2004. The dust trail is not found in optical Palomar images taken June 2003. Both the optical and infrared images show a distinct neck-line tail structure, offset from the projected orbit of the comet. We compare our observations to simulated images using a Monte Carlo approach and a dynamical model for comet dust. We estimate the trail to be at least one orbit old (6.6 years) and consist of particles of size >~100 micron. The neck-line is composed of similar sized particles, particles of size but younger in age. Together, our observations and simulations suggest grains 100 micron and larger in size dominate the total mass ejected from the comet. The radiometric effective radius of the nucleus is 1.87 +/- 0.08 km, derived from the Spitzer observation. The Rosetta spacecraft is expected to arrive at and orbit this comet in 2014. Assuming the trail is comprised solely of 1 mm radius grains, we compute a low probability (~10^-3) of a trail grain impacting with Rosetta during approach and orbit insertion.

  4. Cohort Profile Update: The TRacking Adolescents’ Individual Lives Survey (TRAILS)

    PubMed Central

    Oldehinkel, Albertine J; Rosmalen, Judith GM; Buitelaar, Jan K; Hoek, Hans W; Ormel, Johan; Raven, Dennis; Reijneveld, Sijmen A; Veenstra, René; Verhulst, Frank C; Vollebergh, Wilma AM; Hartman, Catharina A

    2015-01-01

    TRAILS consists of a population cohort (N?=?2230) and a clinical cohort (N?=?543), both of which were followed from about age 11 years onwards. To date, the population cohort has been assessed five times over a period of 11 years, with retention rates ranging between 80% and 96%. The clinical cohort has been assessed four times over a period of 8 years, with retention rates ranging between 77% and 85%. Since the IJE published a cohort profile on the TRAILS in 2008, the participants have matured from adolescents into young adults. The focus shifted from parents and school to entry into the labour market and family formation, including offspring. Furthermore, psychiatric diagnostic interviews were administered, the database was linked to a Psychiatric Case Registry, and the availability of genome-wide SNP variations opened the door to genome-wide association studies regarding a wide range of (endo)phenotypes. With some delay, TRAILS data are available to researchers outside the TRAILS consortium without costs; access can be obtained by submitting a publication proposal (see www.trails.nl). PMID:25431468

  5. RAD001 (everolimus) enhances TRAIL cytotoxicity in human leukemic Jurkat T cells by upregulating DR5.

    PubMed

    Lee, Myoung Woo; Kim, Dae Seong; Eom, Ji-Eun; Ko, Young Jong; Sung, Ki Woong; Koo, Hong Hoe; Yoo, Keon Hee

    2015-08-01

    Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), either alone or in combination with other anti-cancer agents, is a promising new strategy for the treatment of cancer. However, aberrant PI3K/Akt/mTOR survival signaling may confer TRAIL resistance by altering the balance between pro- and anti-apoptotic proteins. In the present study, we showed that the Akt/mTOR inhibitor RAD001 (everolimus) induced cell death in a dose-dependent manner and enhanced TRAIL-induced apoptosis in human leukemic Jurkat T cells, which show PI3K/Akt/mTOR pathway activation and basal expression levels of death receptor (DR) 5 (TRAIL-R2). Investigation of the effect of RAD001 treatment on the expression of TRAIL receptors (TRAIL-Rs) in Jurkat T cells showed that RAD001 significantly upregulated DR5 by up to 51.22%, but not other TRAIL-Rs such as DR4 (TRAIL-R1), decoy receptor (DcR) 1 (TRAIL-R3), and DcR2 (TRAIL-R4). Pretreatment with DR5:Fc chimera abrogated the RAD001-induced increase of TRAIL cytotoxicity, indicating that the upregulation of DR5 by RAD001 plays a role in enhancing the susceptibility of Jurkat T cells to TRAIL. Our results indicate that combination treatment with RAD001 and TRAIL may be a novel therapeutic strategy in leukemia. PMID:26074143

  6. Active Wing Flutter Suppression Using a Trailing Edge Flap

    NASA Astrophysics Data System (ADS)

    Borglund, D.; Kuttenkeuler, J.

    2002-04-01

    The aeroservoelastic behaviour of a thin rectangular wing with a controllable trailing edge flap is investigated. A rather high aspect ratio motivates a numerical model based on linear beam theory for the structural dynamics and strip theory for the unsteady aerodynamic loads. Experimental flutter testing shows good agreement with the numerical stability analysis, and the impact of the trailing edge flap on the dynamics is verified by open-loop testing. The problem of stabilizing the wing utilizing the trailing edge flap is posed, and the design of a fixed-structure feedback controller is performed using numerical optimization. The problem of maximizing closed-loop modal damping with constraints on actuator performance is solved for a sequence of flow speeds and the obtained controller is synthesized using gain scheduling. The fairly large predicted increase in critical speed is experimentally verified with satisfactory accuracy.

  7. Broadband trailing edge noise predictions in the time domain

    NASA Astrophysics Data System (ADS)

    Casper, J.; Farassat, F.

    2004-03-01

    A recently developed analytic result in acoustics, "Formulation 1B," is used to compute broadband trailing edge noise from an unsteady surface pressure distribution on a thin airfoil in the time domain. This formulation is a new solution of the Ffowcs Williams-Hawkings equation with the loading source term, and has been shown in previous research to provide time domain predictions of broadband noise that are in excellent agreement with experimental results. Furthermore, this formulation lends itself readily to rotating reference frames and statistical analysis of broadband trailing edge noise. In the present work, Formulation 1B is used to calculate the farfield noise radiated from the trailing edge of a NACA 0012 airfoil in a low Mach number flow, using both analytical and experimental data on the airfoil surface. The acoustic predictions are compared with analytical results and experimental measurements that are available in the literature. Good agreement between predictions and measurements is obtained.

  8. Broadband Trailing Edge Noise Predictions in the Time Domain. Revised

    NASA Technical Reports Server (NTRS)

    Casper, Jay; Farassat, Fereidoun

    2003-01-01

    A recently developed analytic result in acoustics, "Formulation 1B," is used to compute broadband trailing edge noise from an unsteady surface pressure distribution on a thin airfoil in the time domain. This formulation is a new solution of the Ffowcs Willliams-Hawkings equation with the loading source term, and has been shown in previous research to provide time domain predictions of broadband noise that are in excellent agreement with experimental results. Furthermore, this formulation lends itself readily to rotating reference frames and statistical analysis of broadband trailing edge noise. Formulation 1B is used to calculate the far field noise radiated from the trailing edge of a NACA 0012 airfoil in low Mach number flows, by using both analytical and experimental data on the airfoil surface. The acoustic predictions are compared with analytical results and experimental measurements that are available in the literature. Good agreement between predictions and measurements is obtained.

  9. Trailing Edge Noise Prediction Based on a New Acoustic Formulation

    NASA Technical Reports Server (NTRS)

    Casper, J.; Farassat, F.

    2002-01-01

    A new analytic result in acoustics called 'Formulation 1B,' proposed by Farassat, is used to compute broadband trailing edge noise from an unsteady surface pressure distribution on a thin airfoil in the time domain. This formulation is a new solution of the Ffowcs Williams-Hawkings equation with the loading source term, and has been shown in previous research to provide time domain predictions of broadband noise that are in excellent agreement with experiment. Furthermore, this formulation lends itself readily to rotating reference frames and statistical analysis of broadband trailing edge noise. Formulation 1B is used to calculate the far field noise radiated from the trailing edge of a NACA 0012 airfoil in low Mach number flows, using both analytical and experimental data on the airfoil surface. The results are compared to analytical results and experimental measurements that are available in the literature. Good agreement between predictions and measurements is obtained.

  10. Camping impact management on the Appalachian National Scenic Trail

    USGS Publications Warehouse

    Marion, J.L.

    2003-01-01

    This report addresses the management of overnight use and associated impacts along the Appalachian National Scenic Trail (A.T.). This effort was initiated in response to agency and Appalachian Trail Conference (ATC) management concerns regarding the resource and social impacts of increasing overnight visitation, particularly in high use areas. Report findings and recommendations are primarily based on series of on-site investigations at 17 problem areas selected by A.T. clubs and ATC staff. However, the report?s recommendations also draw on an examination of relevant A.T. legislative, agency, and organization guidance and visitor impact management knowledge derived from research and management experience.

  11. AN ANALYSIS OF THE IMPACT OF SPORTS UTILITY VEHICLES IN THE UNITED STATES

    SciTech Connect

    Davis, S.C.

    2000-08-16

    During the 1990s, sport utility vehicles (SUVs) became the fastest growing segment of the auto industry, especially those in the medium-size category. In 1999, SUV sales reached almost 19% of the total light vehicle market and the mix of SUVs on the road, as measured by registration data, was about 8.7%. This immense popularity has been called by some a passing fad--vehicle purchases based on the SUV ''image''. But the continued yearly increases in SUV sales seem to indicate a more permanent trend. Additional explanations for SUV popularity include the general economic well being in the United States, a perception of safety, and ''utility''. Generally larger and heavier than the typical automobile, SUVs require more fuel per mile to operate and produce greater amounts of pollutants. They are also driven further annually than are automobiles of the same vintage, a fact that exacerbates the fuel-use and emission problems. Although buyers believe that SUVs are safer than automobiles which they are in some cases, SUVs are more prone to roll-overs than are automobiles. In addition, SUVs, with their higher bumpers and greater weight, may be a threat to other vehicles on the highway, especially in side-impact crashes. With sales projected to grow to over 3 million units per year beginning in 2001, SUVs show no sign of decreasing in popularity. These vehicles are used primarily for general mobility, rather than off-road activities. An emphasis on better fuel economy and improved emissions control could address environmental and oil dependency concerns. In fact, recently, two vehicle manufacturers announced intentions of improving the fuel economy of their SUVs in the next few years. Also, tests simulating crashes involving automobiles and SUVs could provide valuable data for identifying potential safety design issues. It is clear that automobiles and SUVs will be sharing the highways for years to come.

  12. 30 CFR 75.607 - Breaking trailing cable and power cable connections.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...false Breaking trailing cable and power cable connections. 75.607 Section...ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY...607 Breaking trailing cable and power cable connections. [Statutory...

  13. 30 CFR 75.607 - Breaking trailing cable and power cable connections.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...false Breaking trailing cable and power cable connections. 75.607 Section...ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY...607 Breaking trailing cable and power cable connections. [Statutory...

  14. 30 CFR 75.607 - Breaking trailing cable and power cable connections.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...false Breaking trailing cable and power cable connections. 75.607 Section...ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY...607 Breaking trailing cable and power cable connections. [Statutory...

  15. 30 CFR 75.607 - Breaking trailing cable and power cable connections.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...false Breaking trailing cable and power cable connections. 75.607 Section...ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY...607 Breaking trailing cable and power cable connections. [Statutory...

  16. 30 CFR 75.607 - Breaking trailing cable and power cable connections.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...false Breaking trailing cable and power cable connections. 75.607 Section...ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY...607 Breaking trailing cable and power cable connections. [Statutory...

  17. 49 CFR 230.98 - Driving, trailing, and engine truck axles.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Driving, trailing, and engine truck axles. 230.98...DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Steam Locomotives and Tenders ...Driving, trailing, and engine truck axles. (a)...

  18. 49 CFR 230.98 - Driving, trailing, and engine truck axles.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Driving, trailing, and engine truck axles. 230.98...DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Steam Locomotives and Tenders ...Driving, trailing, and engine truck axles. (a)...

  19. 49 CFR 230.98 - Driving, trailing, and engine truck axles.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Driving, trailing, and engine truck axles. 230.98...DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Steam Locomotives and Tenders ...Driving, trailing, and engine truck axles. (a)...

  20. 49 CFR 230.98 - Driving, trailing, and engine truck axles.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Driving, trailing, and engine truck axles. 230.98...DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Steam Locomotives and Tenders ...Driving, trailing, and engine truck axles. (a)...

  1. 49 CFR 230.98 - Driving, trailing, and engine truck axles.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Driving, trailing, and engine truck axles. 230.98...DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Steam Locomotives and Tenders ...Driving, trailing, and engine truck axles. (a)...

  2. Assessing and Understanding Trail Degradation: Results from Big South Fork National River and Recreational Area

    USGS Publications Warehouse

    Marion, J.L.; Olive, N.

    2006-01-01

    This report describes results from a comprehensive assessment of resource conditions on a large (24%) sample of the trail system within Big South Fork National River and Recreational Area (BSF). Components include research to develop state-of-knowledge trail impact assessment and monitoring methods, application of survey methods to BSF trails, analysis and summary of results, and recommendations for trail management decision making and future monitoring. Findings reveal a trail system with some substantial degradation, particularly soil erosion, which additionally threatens water quality in areas adjacent to streams and rivers. Factors that contribute to or influence these problems are analyzed and described. Principal among these are trail design factors (trail topographic position, soil texture, grade and slope alignment angle), use-related factors (type and amount of use), and maintenance factors (water drainage). Recommendations are offered to assist managers in improving the sustainability of the trails system to accommodate visitation while enhancing natural resource protection.

  3. 77 FR 37438 - Draft Trail Management Plan and Environmental Impact Statement for Cuyahoga Valley National Park...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ...trail networks, and change in outdoor recreation trends. Several alternative actions...partners. Alternative 3A--Recreation Focus: ``Trail Hubs'' will...activities. Alternative 3B--Recreation Focus with Mountain Bike...

  4. 30 CFR 77.804 - High-voltage trailing cables; minimum design requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...High-Voltage Distribution § 77.804 High-voltage trailing cables; minimum design requirements. (a) High-voltage trailing cables used in resistance grounded systems...with metallic shields around each power conductor with one or more...

  5. Electric vehicles

    SciTech Connect

    Not Available

    1990-03-01

    Quiet, clean, and efficient, electric vehicles (EVs) may someday become a practical mode of transportation for the general public. Electric vehicles can provide many advantages for the nation's environment and energy supply because they run on electricity, which can be produced from many sources of energy such as coal, natural gas, uranium, and hydropower. These vehicles offer fuel versatility to the transportation sector, which depends almost solely on oil for its energy needs. Electric vehicles are any mode of transportation operated by a motor that receives electricity from a battery or fuel cell. EVs come in all shapes and sizes and may be used for different tasks. Some EVs are small and simple, such as golf carts and electric wheel chairs. Others are larger and more complex, such as automobile and vans. Some EVs, such as fork lifts, are used in industries. In this fact sheet, we will discuss mostly automobiles and vans. There are also variations on electric vehicles, such as hybrid vehicles and solar-powered vehicles. Hybrid vehicles use electricity as their primary source of energy, however, they also use a backup source of energy, such as gasoline, methanol or ethanol. Solar-powered vehicles are electric vehicles that use photovoltaic cells (cells that convert solar energy to electricity) rather than utility-supplied electricity to recharge the batteries. This paper discusses these concepts.

  6. 77 FR 61428 - Notice of Meeting for Star-Spangled Banner National Historic Trail Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-09

    ... National Park Service Notice of Meeting for Star-Spangled Banner National Historic Trail Advisory Council... on the Star-Spangled Banner National Historic Trail will hold a meeting. Designated through an... John Maounis, Superintendent, Star Spangled Banner National Historic Trail, telephone: (410)...

  7. Activation of the Akt Survival Pathway Contributes to TRAIL Resistance in Cancer Cells

    PubMed Central

    Xu, Jing; Zhou, Jun-Ying; Wei, Wei-Zen; Wu, Gen Sheng

    2010-01-01

    The mechanism of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) resistance in cancer cells is not fully understood. Here, we show that the Akt survival pathway plays an important role in TRAIL resistance in human cancer cells. Specifically, we found that TRAIL treatment activates the Akt survival pathway and that inhibition of this pathway by the PI3K inhibitor LY294002 or knockdown of Akt sensitizes resistant cancer cells to TRAIL. Since Akt is negatively regulated by the tumor suppressor PTEN, we examined the TRAIL sensitivity in PTEN knockdown mouse prostate epithelial cells and found that PTEN?/? cells are more resistant than PTEN+/+ cells while the sensitivity of PTEN+/? cells fell in between. Further, we showed that overexpression of a mutant PTEN confers TRAIL resistance in PTEN+/+ cells, supporting a role of PTEN in TRAIL sensitivity. In TRAIL resistant breast T47D cells, overexpression of the mutant PTEN further increased their resistance to TRAIL. Taken together, our data indicate that inactivation of functional PTEN and the consequent activation of the Akt pathway prevents TRAIL-induced apoptosis, leading to TRAIL resistance. Therefore, our results suggest that TRAIL resistance can be overcome by targeting PTEN or the Akt survival pathway in cancer cells. PMID:20419107

  8. Investigation into Sources of High Nitrate Concentrations in Orange Trail Creek, State Botanical Garden of Georgia

    E-print Network

    Radcliffe, David

    Investigation into Sources of High Nitrate Concentrations in Orange Trail Creek, State Botanical Garden of Georgia David Radcliffe1 and Karin Lichtenstein2 Abstract Sampling of the Orange Trail Creek groundwater moves rapidly to springs that are headwaters of the eastern branches of the Orange Trail Creek

  9. Interpretation of non-specular radar meteor trails Lars P. Dyrud,1

    E-print Network

    Oppenheim, Meers

    Interpretation of non-specular radar meteor trails Lars P. Dyrud,1 Meers M. Oppenheim,1 Sigrid. [1] Radar data of non-specular meteor trails shows two clear and consistent features: (1) non­specular meteor trails are observed from a narrower altitude range than are head echoes and (2) an approximately

  10. ORIGINAL ARTICLE An experimental investigation on the trailing edge cooling of

    E-print Network

    Hu, Hui

    characteristics of the wall jets pertinent to trailing edge cooling of turbine blades. A high particularly concern with the trailing edge cooling design of turbine blades. The trailing edges of modern high pressure turbine blades are usually cooled by jets blown tangentially through a breakout slot

  11. Trail Pheromone of the Argentine Ant, Linepithema humile (Mayr) (Hymenoptera: Formicidae)

    PubMed Central

    Choe, Dong-Hwan; Villafuerte, David B.; Tsutsui, Neil D.

    2012-01-01

    The Argentine ant (Linepithema humile) is recognized as one of the world's most damaging invasive species. One reason for the ecological dominance of introduced Argentine ant populations is their ability to dominate food and habitat resources through the rapid mobilization and recruitment of thousands of workers. More than 30 years ago, studies showed that (Z)-9-hexadecenal strongly attracted Argentine ant workers in a multi-choice olfactometer, suggesting that (Z)-9-hexadecenal might be the trail pheromone, or a component of a trail pheromone mixture. Since then, numerous studies have considered (Z)-9-hexadecenal as the key component of the Argentine ant trails. Here, we report the first chemical analyses of the trails laid by living Argentine ants and find that (Z)-9-hexadecenal is not present in a detectible quantity. Instead, two iridoids, dolichodial and iridomyrmecin, appear to be the primary chemical constituents of the trails. Laboratory choice tests confirmed that Argentine ants were attracted to artificial trails comprised of these two chemicals significantly more often than control trails. Although (Z)-9-hexadecenal was not detected in natural trails, supplementation of artificial dolichodial+iridomyrmecin trails with an extremely low concentraion of (Z)-9-hexadecenal did increase the efficacy of the trail-following behavior. In stark contrast with previous dogma, our study suggests that dolichodial and iridomyrmecin are major components of the Argentine ant trail pheromone. (Z)-9-hexadecenal may act in an additive manner with these iridoids, but it does not occur in detectable quantities in Argentine ant recruitment trails. PMID:23028739

  12. Verifiable Audit Trails for a Versioning File System Randal Burns, Zachary Peterson, Giuseppe Ateniese, Stephen Bono

    E-print Network

    Ateniese, Giuseppe

    Verifiable Audit Trails for a Versioning File System Randal Burns, Zachary Peterson, Giuseppe constructs that create, manage, and verify dig- ital audit trails for versioning file systems. Based upon. Audit trails create an analog of the paper audit process for file data, helping to meet the requirements

  13. Proc. of Internet Society INET `99 Electronic Commerce with Verifiable Audit Trails

    E-print Network

    Peha, Jon M.

    Proc. of Internet Society INET `99 Electronic Commerce with Verifiable Audit Trails Jon M. Peha protection for all parties, while simultaneously producing a detailed audit trail. Any attempt to falsify this audit trail should face significant risk of detection, even if multiple parties cooperate

  14. 30 CFR 75.906 - Trailing cables for mobile equipment, ground wires, and ground check wires.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Trailing cables for mobile equipment, ground... Underground Low- and Medium-Voltage Alternating Current Circuits § 75.906 Trailing cables for mobile equipment, ground wires, and ground check wires. Trailing cables for mobile equipment shall contain one or...

  15. A Search for Comet Debris Trails in the Spitzer FLS Fields

    NASA Astrophysics Data System (ADS)

    Walker, Russell; Lien, David; Sykes, Mark

    2004-09-01

    We propose to identify serendipitous detections of comet dust trails in the Spitzer First Look Survey fields. This will include debris in the orbits of known short-period comets as well as 'orphan' trails. This will allow us to determine the number density of trails, the fraction associated with known short-period comets, the extent of trails along comet orbits, whether the distribution of orphans in ecliptic latitude suggest a cometary or asteroidal origin, whether communition of trail particles would allow for comets to be a significant contributor to the broad thermal emission of the zodiacal dust complex, and whether the physical properties of trail particles vary from comet to comet (suggesting different origins). Analysis of detected trails will allow us to determine the temperature and optical depth of the grains, the emission velocities and ages of the trail particles, comet mass loss rates, and constrain comet dust-to-volatile mass ratios. The database of detected comet trails and their thermal radiance will generate important follow-on science by future Spitzer GO trail observations. Trail search techniques and software developed here will serve as a pilot study for efficient trail searches in more extensive programs such as SWIRE.

  16. Comprehensive Trail Making Test Performance in Children and Adolescents with Traumatic Brain Injury

    ERIC Educational Resources Information Center

    Allen, Daniel N.; Thaler, Nicholas S.; Ringdahl, Erik N.; Barney, Sally J.; Mayfield, Joan

    2012-01-01

    The sensitivity of the Trail Making Test to brain damage has been well-established over many years, making it one of the most commonly used tests in clinical neuropsychological evaluations. The current study examined the validity of scores from a newer version of the Trail Making Test, the Comprehensive Trail Making Test (CTMT), in children and…

  17. Reduction of the shock wave intensity by modifying the transonic blade trailing edge

    NASA Technical Reports Server (NTRS)

    Doerffer, P.

    1983-01-01

    It is shown that the shock wave intensity can be decreased by using modified trailing edge configurations to reduce or even completely compensate for the effect of the finite thickness of the trailing edge. A theoretical analysis is presented together with numerical results for two supersonic streams flowing off the trailing edge at different velocities. The analysis is based on an ideal gas model.

  18. A spatial exploration of informal trail networks within Great Falls Park, VA

    USGS Publications Warehouse

    Wimpey, Jeremy; Marion, Jeffrey L.

    2011-01-01

    Informal (visitor-created) trails represent a threat to the natural resources of protected natural areas around the globe. These trails can remove vegetation, displace wildlife, alter hydrology, alter habitat, spread invasive species, and fragment landscapes. This study examines informal and formal trails within Great Falls Park, VA, a sub-unit of the George Washington Memorial Parkway, managed by the U.S. National Park Service. This study sought to answer three specific questions: 1) Are the physical characteristics and topographic alignments of informal trails significantly different from formal trails, 2) Can landscape fragmentation metrics be used to summarize the relative impacts of formal and informal trail networks on a protected natural area? and 3) What can we learn from examining the spatial distribution of the informal trails within protected natural areas? Statistical comparisons between formal and informal trails in this park indicate that informal trails have less sustainable topographic alignments than their formal counterparts. Spatial summaries of the lineal and areal extent and fragmentation associated with the trail networks by park management zones compare park management goals to the assessed attributes. Hot spot analyses highlight areas of high trail density within the park and findings provide insights regarding potential causes for development of dense informal trail networks.

  19. Armored Vehicle 

    E-print Network

    Unknown

    2011-09-05

    accurate vehicle state estimates for simple ground vehicles are identi ed and the bene ts of integrated estimation and control are investigated. It is demonstrated that considering estimation accuracy is essential to produce e cient guidance and control... an unmanned ground vehicle (UGV) [12], [22], [33], [42]. The primary interest of this portion of research lies in the integration of estimation and control to provide e cient, accurate guidance. It has been well documented that additional accelerations...

  20. 30 CFR 56.12038 - Attachment of trailing cables.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Attachment of trailing cables. 56.12038 Section 56.12038 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  1. 30 CFR 56.12039 - Protection of surplus trailing cables.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Protection of surplus trailing cables. 56.12039 Section 56.12039 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  2. 30 CFR 56.12003 - Trailing cable overload protection.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Trailing cable overload protection. 56.12003 Section 56.12003 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  3. Basic Sequence Analysis Techniques for Use with Audit Trail Data

    ERIC Educational Resources Information Center

    Judd, Terry; Kennedy, Gregor

    2008-01-01

    Audit trail analysis can provide valuable insights to researchers and evaluators interested in comparing and contrasting designers' expectations of use and students' actual patterns of use of educational technology environments (ETEs). Sequence analysis techniques are particularly effective but have been neglected to some extent because of real…

  4. Trail Camera Installation to Monitor Erosion along Missouri River

    USGS Multimedia Gallery

    A South Dakota School of Mines and Technology student working for the USGS South Dakota Water Science Center installed a trail camera in the fall of 2013 on a pole at the Playground site to take time-lapse images of shoreline erosion along the Missouri River near the town of Lower Brule on...

  5. Trail Camera Installation to Monitor Erosion along Missouri River

    USGS Multimedia Gallery

    A South Dakota School of Mines and Technology student working for the USGS South Dakota Water Science Center installed a trail camera at the Lodge site in the fall of 2013 to take time-lapse images of shoreline erosion along the Missouri River near the town of Lower Brule on the Lower Brule Res...

  6. Trail Re-identification and Unlinkability in Distributed Databases

    E-print Network

    in this research are solely those of the author and do not necessarily reflect those of the United States be strengthened with formal computational models for privacy technology. In this work, trails are studied in two real world databases, including hospital visits derived from medical databases and weblogs derived from

  7. On the Trail of Facial Processing in Autism Spectrum Disorders

    E-print Network

    Deussen, Oliver

    On the Trail of Facial Processing in Autism Spectrum Disorders Diana Arellano1(B) , Ulrich Max perception deficits in individuals with autism spectrum disorders (ASD), we propose the project SARA. Its. Keywords: Autism spectrum disorders · Real-time NPR · Abstraction · 3D characters · Dynamic facial

  8. The Work We Do: Journal as Audit Trail.

    ERIC Educational Resources Information Center

    Harste, Jerome C.; Vasquez, Vivian

    1998-01-01

    Offers a peek inside the journals kept by a well-known language-arts educator, which he uses as a repository for his thoughts, drawings, articles of interest, notes from conversations with others on his own work, the work of others, and education in general. Shows how the journal is an "audit trail" of its owner's learning. (SR)

  9. Dust trailing from the top chord, the bridge falls toward ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Dust trailing from the top chord, the bridge falls toward the river, as the southwest end (right) falls first. View southeast from confluence of Trinity and South Fork Trinity Rivers - South Fork Trinity River Bridge, State Highway 299 spanning South Fork Trinity River, Salyer, Trinity County, CA

  10. eXcitingTrails/Events: Events for Touristic Scenarios

    E-print Network

    da Silva, Alberto Rodrigues

    eXcitingTrails/Events: Events for Touristic Scenarios Ana Isabel Morais Belchior Dissertation, and to my father, for guiding me to accomplish my goals. To my sisters, for being there when I needed and culture. Mobile guides are becoming the standard tool to use in these kind of activities, since

  11. Observations of persistent Leonid meteor trails 3. The ``Glowworm''

    E-print Network

    Chu, Xinzhao

    Observations of persistent Leonid meteor trails 3. The ``Glowworm'' Jack D. Drummond,1 Brent W August 2002. [1] A spectacular, well-observed Leonid meteor of visual magnitude À14.3 appeared on 17 s after the meteor and recorded a video with an intensified camera for even longer. From information

  12. 30 CFR 56.12038 - Attachment of trailing cables.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Attachment of trailing cables. 56.12038 Section 56.12038 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  13. 30 CFR 56.12039 - Protection of surplus trailing cables.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Protection of surplus trailing cables. 56.12039 Section 56.12039 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  14. 30 CFR 56.12003 - Trailing cable overload protection.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Trailing cable overload protection. 56.12003 Section 56.12003 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  15. 30 CFR 56.12038 - Attachment of trailing cables.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Attachment of trailing cables. 56.12038 Section 56.12038 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  16. 30 CFR 56.12003 - Trailing cable overload protection.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Trailing cable overload protection. 56.12003 Section 56.12003 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  17. 30 CFR 56.12039 - Protection of surplus trailing cables.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Protection of surplus trailing cables. 56.12039 Section 56.12039 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  18. 30 CFR 56.12038 - Attachment of trailing cables.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Attachment of trailing cables. 56.12038 Section 56.12038 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  19. 30 CFR 56.12003 - Trailing cable overload protection.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Trailing cable overload protection. 56.12003 Section 56.12003 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  20. 30 CFR 56.12039 - Protection of surplus trailing cables.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Protection of surplus trailing cables. 56.12039 Section 56.12039 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  1. 30 CFR 56.12039 - Protection of surplus trailing cables.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Protection of surplus trailing cables. 56.12039 Section 56.12039 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  2. 30 CFR 56.12003 - Trailing cable overload protection.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Trailing cable overload protection. 56.12003 Section 56.12003 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  3. 30 CFR 56.12038 - Attachment of trailing cables.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Attachment of trailing cables. 56.12038 Section 56.12038 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES...

  4. 9. VIEW FROM MANY PARKS CURVE (ON TRAIL RIDGE ROAD) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. VIEW FROM MANY PARKS CURVE (ON TRAIL RIDGE ROAD) OF HORSESHOE PARK, SHOWING FALL RIVER ROAD FAINTLY AT LEFT AT BASE OF SHEEP MOUNTAIN AND CROSSING ALLUVIAL FAN FROM LAWN LAKE FLOOD. - Fall River Road, Between Estes Park & Fall River Pass, Estes Park, Larimer County, CO

  5. Chattanooga Math Trail: Community Mathematics Modules, Volume 1.

    ERIC Educational Resources Information Center

    McAllister, Deborah A.; Mealer, Adrian; Moyer, Peggy S.; McDonald, Shirley A.; Peoples, John B.

    This collection of community mathematics modules, or "math trail", is appropriate for middle grades and high school students (grades 5-12). Collectively, the modules pay attention to all 10 of the National Council of Teachers of Mathematics (NCTM) standards which include five content standards (Number and Operations, Algebra, Geometry,…

  6. 36 CFR 7.100 - Appalachian National Scenic Trail.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... right-of-way reserved by the seller or by public road right-of-way. You may also cross National Park... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Appalachian National Scenic Trail. 7.100 Section 7.100 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF...

  7. 36 CFR 7.100 - Appalachian National Scenic Trail.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... right-of-way reserved by the seller or by public road right-of-way. You may also cross National Park... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Appalachian National Scenic Trail. 7.100 Section 7.100 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF...

  8. 36 CFR 7.100 - Appalachian National Scenic Trail.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... right-of-way reserved by the seller or by public road right-of-way. You may also cross National Park... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Appalachian National Scenic Trail. 7.100 Section 7.100 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF...

  9. 36 CFR 7.100 - Appalachian National Scenic Trail.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... right-of-way reserved by the seller or by public road right-of-way. You may also cross National Park... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Appalachian National Scenic Trail. 7.100 Section 7.100 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF...

  10. 36 CFR 7.100 - Appalachian National Scenic Trail.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... right-of-way reserved by the seller or by public road right-of-way. You may also cross National Park... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Appalachian National Scenic Trail. 7.100 Section 7.100 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF...

  11. Endonucleases induced TRAIL-insensitive apoptosis in ovarian carcinoma cells

    SciTech Connect

    Geel, Tessa M.; Meiss, Gregor; Gun, Bernardina T. van der; Kroesen, Bart Jan; Leij, Lou F. de; Zaremba, Mindaugas; Silanskas, Arunas; Kokkinidis, Michael; Ruiters, Marcel H.; Synvolux therapeutics, Groningen ; McLaughlin, Pamela M.; Rots, Marianne G.

    2009-09-10

    TRAIL induced apoptosis of tumor cells is currently entering phase II clinical settings, despite the fact that not all tumor types are sensitive to TRAIL. TRAIL resistance in ovarian carcinomas can be caused by a blockade upstream of the caspase 3 signaling cascade. We explored the ability of restriction endonucleases to directly digest DNA in vivo, thereby circumventing the caspase cascade. For this purpose, we delivered enzymatically active endonucleases via the cationic amphiphilic lipid SAINT-18{sup Registered-Sign }:DOPE to both TRAIL-sensitive and insensitive ovarian carcinoma cells (OVCAR and SKOV-3, respectively). Functional nuclear localization after delivery of various endonucleases (BfiI, PvuII and NucA) was indicated by confocal microscopy and genomic cleavage analysis. For PvuII, analysis of mitochondrial damage demonstrated extensive apoptosis both in SKOV-3 and OVCAR. This study clearly demonstrates that cellular delivery of restriction endonucleases holds promise to serve as a novel therapeutic tool for the treatment of resistant ovarian carcinomas.

  12. The dust trail of comet Churyumov-Gerasimenko near aphelion

    NASA Astrophysics Data System (ADS)

    Agarwal, J.; Mueller, M.; Boehnhardt, H.; Gruen, E.

    We present optical and infrared (24 µm) images of the dust trail of comet 67P/Churyumov-Gerasimenko near aphelion, obtained with the Wide Field Imager at the MPG/ESO 2.2m telescope in La Silla in 2004 and with NASA's Spitzer Space Telescope in 2005 and 2006, respectively. Based on these images, we constrain the size distribution and material properties of mm-sized dust grains emitted from the comet. These particles remain close to the comet's orbit because of weak radiation pressure and low emission speeds, thereby forming the comet's dust trail. We evaluate the size distribution of the trail particles by fitting simulated images to the measured intensities. As far as possible, the parameters of the underlying model are derived from the observed emission history of Churyumov-Gerasimenko. The size distribution is a crucial parameter for estimating the number density of large particles in the neighbourhood of the comet nucleus and for the safety of ESA's Rosetta spacecraft which will pass through the trail region on its approach to Churyumov-Gerasimenko in 2013.

  13. The Dust Trail of Comet Churyumov-Gerasimenko Near Aphelion

    NASA Astrophysics Data System (ADS)

    Gruen, Eberhard; Agarwal, J.; Mueller, M.; Boehnhardt, H.; Reach, W. T.; Sykes, M. V.; Lien, D. J.

    2006-09-01

    We present optical and infrared (24 micron) images of the dust trail of comet 67P/Churyumov-Gerasimenko near aphelion, obtained with the Wide Field Imager at the MPG/ESO 2.2m telescope in La Silla in 2004 and with NASA's Spitzer Space Telescope in 2005 and 2006, respectively. Based on these images, we constrain the size distribution and material properties of mm-sized dust grains emitted from the comet. These particles remain close to the comet's orbit because of weak radiation pressure and low emission speeds, thereby forming the comet's dust trail. We evaluate the size distribution of the trail particles by fitting simulated images to the measured intensities. As far as possible, the parameters of the underlying model are derived from the observed emission history of Churyumov-Gerasimenko. The size distribution is a crucial parameter for estimating the number density of large particles in the neighbourhood of the comet nucleus and for the safety of ESA's Rosetta spacecraft which will pass through the trail region on its approach to Churyumov-Gerasimenko in 2013. This research is supported by NASA and the Studienstiftung des deutschen Volkes

  14. 14. VIEW FROM TUNDRA CURVES (ON TRAIL RIDGE ROAD) SHOWING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. VIEW FROM TUNDRA CURVES (ON TRAIL RIDGE ROAD) SHOWING FALL RIVER ROAD RISING FROM BENEATH CHAPIN PASS (AT EXTREME RIGHT) TO FALL RIVER PASS (FAR LEFT). - Fall River Road, Between Estes Park & Fall River Pass, Estes Park, Larimer County, CO

  15. 30 CFR 57.4057 - Underground trailing cables.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Underground trailing cables. 57.4057 Section 57.4057 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire...

  16. Two Bridges Formation on the Navajo Loop Trail

    USGS Multimedia Gallery

    Views along the Navajo Loop Trail in Bryce Canyon National Park. Bryce Canyon is a unique sandstone formation in southern Utah. It is home to a large number of hoodoos, which are oddly shaped pillars of rock that formed due to different erosion rates for the dolomite that caps them and the sandston...

  17. The Clam Trail: Blending Science Education, Public Art, and Tourism

    ERIC Educational Resources Information Center

    Muscio, Cara; Flimlin, Gef; Bushnell, Rick

    2011-01-01

    The Barnegat Bay Shellfish Restoration's Clam Trail is an award-winning scavenger hunt that combines science education, public art, and tourism. This family adventure has participants seeking out giant painted fiberglass clams, upweller clam nurseries, and points of interest in search of science facts to record on their forms. Upon returning these…

  18. HIGH-ANGLE AEOLIAN CROSSBEDDING AT TRAIL RIDGE, FLORIDA.

    USGS Publications Warehouse

    Force, Eric; Garnar, Tom

    1985-01-01

    This paper described new evidence concerning the origin of the Trail Ridge mineral sands deposit in Florida. Rarely exposed sections of the orebody exhibit structures indicative of sand dune formation rather than coastal beach sand accumulation. The implications for mineral sands exploration, and therefore resources, in the southeastern USA are highlighted.

  19. 36 CFR 13.1308 - Harding Icefield Trail.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Harding Icefield Trail. 13.1308 Section 13.1308 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR NATIONAL PARK SYSTEM UNITS IN ALASKA Special Regulations-Kenai Fjords National Park...

  20. 36 CFR 13.1308 - Harding Icefield Trail.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Harding Icefield Trail. 13.1308 Section 13.1308 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR NATIONAL PARK SYSTEM UNITS IN ALASKA Special Regulations-Kenai Fjords National Park...

  1. 36 CFR 13.1308 - Harding Icefield Trail.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Harding Icefield Trail. 13.1308 Section 13.1308 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR NATIONAL PARK SYSTEM UNITS IN ALASKA Special Regulations-Kenai Fjords National Park...

  2. 36 CFR 13.1308 - Harding Icefield Trail.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Harding Icefield Trail. 13.1308 Section 13.1308 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR NATIONAL PARK SYSTEM UNITS IN ALASKA Special Regulations-Kenai Fjords National Park...

  3. 36 CFR 13.1308 - Harding Icefield Trail.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Harding Icefield Trail. 13.1308 Section 13.1308 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR NATIONAL PARK SYSTEM UNITS IN ALASKA Special Regulations-Kenai Fjords National Park...

  4. Elephant trail runoff and sediment dynamics in northern Thailand.

    PubMed

    Sidle, Roy C; Ziegler, Alan D

    2010-01-01

    Although elephants may exert various impacts on the environment, no data are available on the effects of elephant trails on runoff, soil erosion, and sediment transport to streams during storms. We monitored water and sediment fluxes from an elephant trail in northern Thailand during seven monsoon storms representing a wide range of rainfall energies. Runoff varied from trivial amounts to 353 mm and increased rapidly in tandem with expanding contributing areas once a threshold of wetting occurred. Runoff coefficients during the two largest storms were much higher than could be generated from the trail itself, implying a 4.5- to 7.9-fold increase in the drainage areas contributing to storm runoff. Clockwise hysteresis patterns of suspended sediment observed during most storms was amplified by a "first flush" of sediment early on the hydrograph in which easily entrained sediment was transported. As runoff areas expanded during the latter part of large storms, discharge increased but sediment concentrations declined. Thus, sediment flux was better correlated to kinetic energy of rainfall on the falling limbs of most storm hydrographs compared to rising limbs. Based on a power function relationship between sediment flux and storm kinetic energy, the estimated annual sediment yield from the trail for 135 storms in 2005 was 308 to 375 Mg ha(-1) yr(-1), higher than from most disturbed land surfaces in the tropics. The eight largest storms (30% of total storm energy) in 2005 transported half of the total annual sediment. These measurements together with site investigations reveal that highly interconnected elephant trails, together with other source areas, directly link runoff and sediment to streams. PMID:20400583

  5. Study of the Correlation between the Performances of Lunar Vehicle Wheels Predicted by the Nepean Wheeled Vehicle Performance Model and Test Data

    NASA Technical Reports Server (NTRS)

    Wong, J. Y.; Asnani, V. M.

    2008-01-01

    This paper describes the results of a study of the correlation between the performances of wheels for lunar vehicles predicted using the Nepean wheeled vehicle performance model (NWVPM), developed under the auspices of Vehicle Systems Development Corporation, Ottawa, Canada, and the corresponding test data presented in Performance evaluation of wheels for lunar vehicles , Technical Report M-70-2, prepared for George C. Marshall Space Flight Center, National Aeronautics and Space Administration (NASA), USA, by the US Army Engineer Waterways Experiment Station (WES). The NWVPM was originally developed for design and performance evaluation of terrestrial off-road wheeled vehicles. The purpose of this study is to assess the potential of the NWVPM for evaluating wheel candidates for the new generation of extra-terrestrial vehicles. Two versions of a wire-mesh wheel and a hoop-spring wheel, which were considered as candidates for lunar roving vehicles for the NASA Apollo program in the late 1960s, together with a pneumatic wheel were examined in this study. The tractive performances of these wheels and of a 464 test vehicle with the pneumatic wheels on air-dry sand were predicted using the NWVPM and compared with the corresponding test data obtained under Earth s gravity and previously documented in the above-named report. While test data on wheel or vehicle performances obtained under Earth s gravity may not necessarily be representative of those on extra-terrestrial bodies, because of the differences in gravity and in environmental conditions, such as atmospheric pressure, it is still a valid approach to use test data obtained under Earth s gravity to evaluate the predictive capability of the NWVPM and its potential applications to predicting wheel or wheeled rover performances on extra-terrestrial bodies. Results of this study show that, using the ratio (P20/W) of the drawbar pull to normal load at 20 per cent slip as a performance indicator, there is a reasonable correlation between the predictions and experimental data. This indicates that the NWVPM has the potential as an engineering tool for evaluating wheel candidates for a future generation of extra-terrestrial vehicles, provided that appropriate input data are available.

  6. 29 CFR 1918.65 - Mechanically powered vehicles used aboard vessels.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...electrical system except when power is necessary for testing and...The employer shall require drivers to ascend and descend grades...the employer shall require drivers to travel with the load trailing...the vehicle is equipped with power steering. (5) When...

  7. 29 CFR 1918.65 - Mechanically powered vehicles used aboard vessels.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...electrical system except when power is necessary for testing and...The employer shall require drivers to ascend and descend grades...the employer shall require drivers to travel with the load trailing...the vehicle is equipped with power steering. (5) When...

  8. 29 CFR 1918.65 - Mechanically powered vehicles used aboard vessels.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...electrical system except when power is necessary for testing and...The employer shall require drivers to ascend and descend grades...the employer shall require drivers to travel with the load trailing...the vehicle is equipped with power steering. (5) When...

  9. Descent vehicles

    NASA Technical Reports Server (NTRS)

    Popov, Y. I.

    1985-01-01

    The creation of descent vehicles marked a new stage in the development of cosmonautics, involving the beginning of manned space flight and substantial progress in space research on the distant bodies of the Solar System. This booklet describes these vehicles and their structures, systems, and purposes. It is intended for the general public interested in modern problems of space technology.

  10. Development & optimization of a rule-based energy management strategy for fuel economy improvement in hybrid electric vehicles

    NASA Astrophysics Data System (ADS)

    Asfoor, Mostafa

    The gradual decline of oil reserves and the increasing demand for energy over the past decades has resulted in automotive manufacturers seeking alternative solutions to reduce the dependency on fossil-based fuels for transportation. A viable technology that enables significant improvements in the overall energy conversion efficiencies is the hybridization of conventional vehicle drive systems. This dissertation builds on prior hybrid powertrain development at the University of Idaho. Advanced vehicle models of a passenger car with a conventional powertrain and three different hybrid powertrain layouts were created using GT-Suite. These different powertrain models were validated against a variety of standard driving cycles. The overall fuel economy, energy consumption, and losses were monitored, and a comprehensive energy analysis was performed to compare energy sources and sinks. The GT-Suite model was then used to predict the formula hybrid SAE vehicle performance. Inputs to this model were a numerically predicted engine performance map, an electric motor torque curve, vehicle geometry, and road load parameters derived from a roll-down test. In this case study, the vehicle had a supervisory controller that followed a rule-based energy management strategy to insure a proper power split during hybrid mode operation. The supervisory controller parameters were optimized using discrete grid optimization method that minimized the total amount of fuel consumed during a specific urban driving cycle with an average speed of approximately 30 [mph]. More than a 15% increase in fuel economy was achieved by adding supervisory control and managing power split. The vehicle configuration without the supervisory controller displayed a fuel economy of 25 [mpg]. With the supervisory controller this rose to 29 [mpg]. Wider applications of this research include hybrid vehicle controller designs that can extend the range and survivability of military combat platforms. Furthermore, the GT-Suite model can be easily accommodated to simulate propulsion systems that store regenerative power when braking, making it available for acceleration and off-road maneuvering.

  11. Recreational Trails Reduce the Density of Ground-Dwelling Birds in Protected Areas

    NASA Astrophysics Data System (ADS)

    Thompson, Bill

    2015-05-01

    Recreational disturbance associated with trails has been identified as one of the major factors causing a decline of native biodiversity within protected areas. However, despite the negative impacts that recreation can have on biodiversity, providing public access to nature is critical for the future of the conservation of biodiversity. As such, many protected area managers are looking for tools to help maintain a balance between public access and biodiversity conservation. The objectives of this study were to examine the impacts of recreational trails on forest-dwelling bird communities in eastern North America, identify functional guilds which are particularly sensitive to recreational trails, and derive guidelines for trail design to assist in managing the impacts of recreational trails on forest-dwelling birds. Trails within 24 publicly owned natural areas were mapped, and breeding bird communities were described with the use of point count surveys. The density of forest birds, particularly of those species which nest or forage on the ground, were significantly positively influenced by the amount of trail-free refuge habitat. Although management options to control trail use in non-staffed protected areas are limited, this study suggests that protected area managers could design and maintain a trail network that would minimize impacts on resident wildlife, while providing recreational opportunities for visitors, by designing their trail network to maximize the area of trail-free habitat.

  12. Recreational trails reduce the density of ground-dwelling birds in protected areas.

    PubMed

    Thompson, Bill

    2015-05-01

    Recreational disturbance associated with trails has been identified as one of the major factors causing a decline of native biodiversity within protected areas. However, despite the negative impacts that recreation can have on biodiversity, providing public access to nature is critical for the future of the conservation of biodiversity. As such, many protected area managers are looking for tools to help maintain a balance between public access and biodiversity conservation. The objectives of this study were to examine the impacts of recreational trails on forest-dwelling bird communities in eastern North America, identify functional guilds which are particularly sensitive to recreational trails, and derive guidelines for trail design to assist in managing the impacts of recreational trails on forest-dwelling birds. Trails within 24 publicly owned natural areas were mapped, and breeding bird communities were described with the use of point count surveys. The density of forest birds, particularly of those species which nest or forage on the ground, were significantly positively influenced by the amount of trail-free refuge habitat. Although management options to control trail use in non-staffed protected areas are limited, this study suggests that protected area managers could design and maintain a trail network that would minimize impacts on resident wildlife, while providing recreational opportunities for visitors, by designing their trail network to maximize the area of trail-free habitat. PMID:25813628

  13. The Prognostic Value of TRAIL and its Death Receptors in Cervical Cancer

    SciTech Connect

    Maduro, John H. Noordhuis, Maartje G.; Hoor, Klaske A. ten; Pras, Elisabeth; Arts, Henriette J.G.; Eijsink, Jasper J.H.; Hollema, Harry; Mom, Constantijne H.; Jong, Steven de; Vries, Elisabeth G.E. de; Bock, Geertruida H. de; Zee, Ate G.J. van der

    2009-09-01

    Purpose: Preclinical data indicate a synergistic effect on apoptosis between irradiation and recombinant human (rh) tumor necrosis factor-related apoptosis inducing ligand (TRAIL), making the TRAIL death receptors (DR) interesting drug targets. The aim of our study was to analyze the expression of DR4, DR5, and TRAIL in cervical cancer and to determine their predictive and prognostic value. Methods and Materials: Tissue microarrays were constructed from tumors of 645 cervical cancer patients treated with surgery and/or (chemo-)radiation between 1980 and 2004. DR4, DR5, and TRAIL expression in the tumor was studied by immunohistochemistry and correlated to clinicopathological variables, response to radiotherapy, and disease-specific survival. Results: Cytoplasmatic DR4, DR5, and TRAIL immunostaining were observed in cervical tumors from 99%, 88%, and 81% of the patients, respectively. In patients treated primarily with radiotherapy, TRAIL-positive tumors less frequently obtained a pathological complete response than TRAIL-negative tumors (66.3% vs. 79.0 %; in multivariate analysis: odds ratio: 2.09, p {<=}0.05). DR4, DR5, and TRAIL expression were not prognostic for disease-specific survival. Conclusions: Immunostaining for DR4, DR5, and TRAIL is frequently observed in the cytoplasm of tumor cells in cervical cancer patients. Absence of TRAIL expression was associated with a higher pathological complete response rate to radiotherapy. DR4, DR5, or TRAIL were not prognostic for disease-specific survival.

  14. Multiple effects of TRAIL in human carcinoma cells: Induction of apoptosis, senescence, proliferation, and cytokine production

    SciTech Connect

    Levina, Vera; Marrangoni, Adele M.; DeMarco, Richard; Gorelik, Elieser; Lokshin, Anna E.

    2008-04-15

    TRAIL is a death ligand that induces apoptosis in malignant but not normal cells. Recently the ability of TRAIL to induce proliferation in apoptosis-resistant normal and malignant cells was reported. In this study, we analyzed TRAIL effects in apoptosis sensitive MCF7, OVCAR3 and H460 human tumor cell lines. TRAIL at low concentrations preferentially induced cell proliferation. At 100 ng/ml, apoptotic death was readily observed, however surviving cells acquired higher proliferative capacity. TRAIL-stimulated production of several cytokines, IL-8, RANTES, MCP-1 and bFGF, and activation of caspases 1 and 8 was essential for this effect. Antibodies to IL-8, RANTES, and bFGF blocked TRAIL-induced cell proliferation and further stimulated apoptosis. For the first time, we report that high TRAIL concentrations induced cell senescence as determined by the altered morphology and expression of several senescence markers: SA-{beta}-gal, p21{sup Waf1/Cip1}, p16{sup INK4a}, and HMGA. Caspase 9 inhibition protected TRAIL-treated cells from senescence, whereas inhibition of caspases 1 and 8 increased the yield of SLP cells. In conclusion, in cultured human carcinoma cells, TRAIL therapy results in three functional outcomes, apoptosis, proliferation and senescence. TRAIL-induced proapoptotic and prosurvival responses correlate with the strength of signaling. TRAIL-induced cytokine production is responsible for its proliferative and prosurvival effects.

  15. The influence of snowmobile trails on coyote movements during winter in high-elevation landscapes.

    PubMed

    Gese, Eric M; Dowd, Jennifer L B; Aubry, Lise M

    2013-01-01

    Competition between sympatric carnivores has long been of interest to ecologists. Increased understanding of these interactions can be useful for conservation planning. Increased snowmobile traffic on public lands and in habitats used by Canada lynx (Lynx canadensis) remains controversial due to the concern of coyote (Canis latrans) use of snowmobile trails and potential competition with lynx. Determining the variables influencing coyote use of snowmobile trails has been a priority for managers attempting to conserve lynx and their critical habitat. During 2 winters in northwest Wyoming, we backtracked coyotes for 265 km to determine how varying snow characteristics influenced coyote movements; 278 km of random backtracking was conducted simultaneously for comparison. Despite deep snow (>1 m deep), radio-collared coyotes persisted at high elevations (>2,500 m) year-round. All coyotes used snowmobile trails for some portion of their travel. Coyotes used snowmobile trails for 35% of their travel distance (random: 13%) for a mean distance of 149 m (random: 59 m). Coyote use of snowmobile trails increased as snow depth and penetrability off trails increased. Essentially, snow characteristics were most influential on how much time coyotes spent on snowmobile trails. In the early months of winter, snow depth was low, yet the snow column remained dry and the coyotes traveled off trails. As winter progressed and snow depth increased and snow penetrability increased, coyotes spent more travel distance on snowmobile trails. As spring approached, the snow depth remained high but penetrability decreased, hence coyotes traveled less on snowmobile trails because the snow column off trail was more supportive. Additionally, coyotes traveled closer to snowmobile trails than randomly expected and selected shallower snow when traveling off trails. Coyotes also preferred using snowmobile trails to access ungulate kills. Snow compaction from winter recreation influenced coyote movements within an area containing lynx and designated lynx habitat. PMID:24367565

  16. [Expression and antitumor activity of fusion protein RGD-TRAIL in Pichia pastoris].

    PubMed

    Wang, Xiao-fei; Chen, Shu-zhen

    2015-05-01

    To compare the activity of RGD-TRAIL in different expression systems, RGD-TRAIL in both Escherichia coli (E.coli) and Pichia pastoris was constructed and expressed. In vitro activity of RGD-TRAIL from Pichia pastoris expression system was also analyzed. Genetic engineering techniques were used to construct recombinant plasmid pET30-rgd-trail and pHBM-rgd-trail. The recombinant protein RGD-TRAIL was purified with Ni ion affinity chromatography after induction. MTT assay, ELISA, scratch wound healing, transwell migration assay and Hoechst 33342 staining were performed to detect the effects of RGD-TRAIL on proliferation, binding activity, migration and apoptosis. The expression of apoptosis-associated proteins was detected by Western blotting. Recombinant protein RGD-TRAIL was successfully expressed in a form of inclusion body in E.coli, while expressed secretorily in Pichia pastoris. It possessed more potent cytotoxicity than RGD-TRAIL in E.coli by MTT assay. The RGD-TRAIL expressed by Pichia pastoris showed powerful binding affinity with cancer cells expressing ?(v), DR4, DR5 and highly potent cytotoxicity through inducing apoptosis of cancer cells. Nuclear fragmentation was examined by Hoechst 33342 staining. Cleaved PARP and caspase-3 were also detected after incubation with RGD-TRAIL. Additionally, RGD-TRAIL inhibited migration significantly in A549 and HT1080 cells. The results demonstrate that Pichia pastoris expression system is more suitable for the recombinant protein RGD-TRAIL. Its binding affinity and antitumor activity might make RGD-TRAIL a promising candidate for cancer therapy. PMID:26234135

  17. The Influence of Snowmobile Trails on Coyote Movements during Winter in High-Elevation Landscapes

    PubMed Central

    Gese, Eric M.; Dowd, Jennifer L. B.; Aubry, Lise M.

    2013-01-01

    Competition between sympatric carnivores has long been of interest to ecologists. Increased understanding of these interactions can be useful for conservation planning. Increased snowmobile traffic on public lands and in habitats used by Canada lynx (Lynx canadensis) remains controversial due to the concern of coyote (Canis latrans) use of snowmobile trails and potential competition with lynx. Determining the variables influencing coyote use of snowmobile trails has been a priority for managers attempting to conserve lynx and their critical habitat. During 2 winters in northwest Wyoming, we backtracked coyotes for 265 km to determine how varying snow characteristics influenced coyote movements; 278 km of random backtracking was conducted simultaneously for comparison. Despite deep snow (>1 m deep), radio-collared coyotes persisted at high elevations (>2,500 m) year-round. All coyotes used snowmobile trails for some portion of their travel. Coyotes used snowmobile trails for 35% of their travel distance (random: 13%) for a mean distance of 149 m (random: 59 m). Coyote use of snowmobile trails increased as snow depth and penetrability off trails increased. Essentially, snow characteristics were most influential on how much time coyotes spent on snowmobile trails. In the early months of winter, snow depth was low, yet the snow column remained dry and the coyotes traveled off trails. As winter progressed and snow depth increased and snow penetrability increased, coyotes spent more travel distance on snowmobile trails. As spring approached, the snow depth remained high but penetrability decreased, hence coyotes traveled less on snowmobile trails because the snow column off trail was more supportive. Additionally, coyotes traveled closer to snowmobile trails than randomly expected and selected shallower snow when traveling off trails. Coyotes also preferred using snowmobile trails to access ungulate kills. Snow compaction from winter recreation influenced coyote movements within an area containing lynx and designated lynx habitat. PMID:24367565

  18. Simulation of Acoustic Scattering from a Trailing Edge

    NASA Technical Reports Server (NTRS)

    Singer, Bart A.; Brentner, Kenneth S.; Lockhard, David P.; Lilley, Geoffrey M.

    1999-01-01

    Three model problems were examined to assess the difficulties involved in using a hybrid scheme coupling flow computation with the the Ffowcs Williams and Hawkings equation to predict noise generated by vortices passing over a sharp edge. The results indicate that the Ffowcs Williams and Hawkings equation correctly propagates the acoustic signals when provided with accurate flow information on the integration surface. The most difficult of the model problems investigated inviscid flow over a two-dimensional thin NACA airfoil with a blunt-body vortex generator positioned at 98 percent chord. Vortices rolled up downstream of the blunt body. The shed vortices possessed similarities to large coherent eddies in boundary layers. They interacted and occasionally paired as they convected past the sharp trailing edge of the airfoil. The calculations showed acoustic waves emanating from the airfoil trailing edge. Acoustic directivity and Mach number scaling are shown.

  19. Simulation of Acoustic Scattering from a Trailing Edge

    NASA Astrophysics Data System (ADS)

    SINGER, B. A.; BRENTNER, K. S.; LOCKARD, D. P.; LILLEY, G. M.

    2000-02-01

    Three model problems were examined to assess the difficulties involved in using a hybrid scheme coupling flow computation with the Ffowcs Williams and Hawkings equation to predict the noise generated by vortices passing over a sharp edge. The results indicate that the Ffowcs Williams and Hawkings equation correctly propagates the acoustic signals when provided with accurate flow information on the integration surface. The most difficult of the model problems investigated flow over a two-dimensional, thin NACA airfoil with a bluff-body vortex generator positioned at 98% chord. Vortices rolled up downstream of the bluff body. The shed vortices possessed similarities to large coherent eddies in boundary layers in that they interacted and occasionally paired as they convected past the sharp trailing edge of the airfoil. The calculations showed acoustic waves emanating from the airfoil trailing edge. Acoustic directivity and Mach number scaling were obtained.

  20. Using external data sources to improve audit trail analysis.

    PubMed

    Herting, R L; Asaro, P V; Roth, A C; Barnes, M R

    1999-01-01

    Audit trail analysis is the primary means of detection of inappropriate use of the medical record. While audit logs contain large amounts of information, the information required to determine useful user-patient relationships is often not present. Adequate information isn't present because most audit trail analysis systems rely on the limited information available within the medical record system. We report a feature of the STAR (System for Text Archive and Retrieval) audit analysis system where information available in the medical record is augmented with external information sources such as: database sources, Light-weight Directory Access Protocol (LDAP) server sources, and World Wide Web (WWW) database sources. We discuss several issues that arise when combining the information from each of these disparate information sources. Furthermore, we explain how the enhanced person specific information obtained can be used to determine user-patient relationships that might signify a motive for inappropriately accessing a patient's medical record. PMID:10566469

  1. Stator Loading Measurements Behind a Fan With Trailing Edge Blowing

    NASA Technical Reports Server (NTRS)

    Waitz, Ian A.

    2000-01-01

    The problem of aircraft noise pollution around airports has become increasingly important as those areas have become more densely populated. Currently, the removal of older noisier aircraft from operation is reducing noise levels around airports; however, with air traffic projected to increase by about 5% over the next decade the number of commercial aircraft operating in the world is expected to be about 17,700 by the year 2007. To keep noise levels around airports from increasing as a result of traffic increases, it is important to investigate new methods of noise reduction. The objective of this work is to provide a better understanding of the effects that trailing edge blowing has on stator unsteady loading. This is done by presenting flowfield and stator loading data from experiments conducted with and without trailing edge blowing.

  2. Low-Speed Fan Noise Reduction With Trailing Edge Blowing

    NASA Technical Reports Server (NTRS)

    Sutliff, Daniel L.; Tweedt, Daniel L.; Fite, E. Brian; Envia, Edmane

    2002-01-01

    An experimental proof-of-concept test was conducted to demonstrate reduction of rotor-stator interaction noise through rotor-trailing edge blowing. The velocity deficit from the viscous wake of the rotor blades was reduced by injecting air into the wake from a trailing edge slot. Composite hollow rotor blades with internal flow passages were designed based on analytical codes modeling the internal flow. The hollow blade with interior guide vanes creates flow channels through which externally supplied air flows from the root of the blade to the trailing edge. The impact of the rotor wake-stator interaction on the acoustics was also predicted analytically. The Active Noise Control Fan, located at the NASA Glenn Research Center, was used as the proof- of-concept test bed. In-duct mode and farfield directivity acoustic data were acquired at blowing rates (defined as mass supplied to trailing edge blowing system divided by fan mass flow) ranging from 0.5 to 2.0 percent. The first three blade passing frequency harmonics at fan rotational speeds of 1700 to 1900 rpm were analyzed. The acoustic tone power levels (PWL) in the inlet and exhaust were reduced 11.5 and -0.1, 7.2 and 11.4, 11.8 and 19.4 PWL dB, respectively. The farfield tone power levels at the first three harmonics were reduced 5.4, 10.6, and 12.4 dB PWL. At selected conditions, two-component hotwire and stator vane unsteady surface pressures were acquired. These measurements illustrate the physics behind the noise reduction.

  3. Tramping Trail with Elroy in the Early Years of CELP

    ERIC Educational Resources Information Center

    O'Krafka, Karen

    2010-01-01

    The author is sipping tea on the eve of a week-long winter trip--over a decade since she first tramped trail with Mike Elrick into the winter wilderness. This evening holds for her the same electricity that it did in 1997--anxiety and excitement--when Elroy guided a motley crew of teens (his gang) into the woods and frozen waters of Algonquin…

  4. CARIBOU WILDERNESS AND TRAIL LAKE ROADLESS AREA, CALIFORNIA.

    USGS Publications Warehouse

    Till, Alison B.; McHugh, Edward L.

    1984-01-01

    A mineral survey of the Caribou Wilderness and Trail Lake Roadless Area conducted in 1979 revealed no indications of a potential for mineral or fossil fuel resources in the areas. The wilderness is in the Cascade volcanic province, a setting locally favorable for geothermal resources, but no geothermal resource potential was identified in the wilderness or roadless area. Regional studies and drilling would be necessary to identify geothermal resource potential.

  5. Robotic vehicle

    DOEpatents

    Box, W.D.

    1998-08-11

    A robotic vehicle is described for travel through a conduit. The robotic vehicle includes forward and rear housings each having a hub portion, and each being provided with surface engaging mechanisms for selectively engaging the walls of the conduit such that the housings can be selectively held in stationary positions within the conduit. The surface engaging mechanisms of each housing includes a plurality of extendible appendages, each of which is radially extendible relative to the operatively associated hub portion between a retracted position and a radially extended position. The robotic vehicle also includes at least three selectively extendible members extending between the forward and rear housings, for selectively changing the distance between the forward and rear housings to effect movement of the robotic vehicle. 20 figs.

  6. Robotic vehicle

    DOEpatents

    Box, W.D.

    1997-02-11

    A robotic vehicle is described for travel through a conduit. The robotic vehicle includes forward and rear housings each having a hub portion, and each being provided with surface engaging mechanisms for selectively engaging the walls of the conduit such that the housings can be selectively held in stationary positions within the conduit. The surface engaging mechanisms of each housing includes a plurality of extendable appendages, each of which is radially extendable relative to the operatively associated hub portion between a retracted position and a radially extended position. The robotic vehicle also includes at least three selectively extendable members extending between the forward and rear housings, for selectively changing the distance between the forward and rear housings to effect movement of the robotic vehicle. 20 figs.

  7. Robotic vehicle

    DOEpatents

    Box, W. Donald (Oak Ridge, TN)

    1998-01-01

    A robotic vehicle for travel through a conduit. The robotic vehicle includes forward and rear housings each having a hub portion, and each being provided with surface engaging mechanisms for selectively engaging the walls of the conduit such that the housings can be selectively held in stationary positions within the conduit. The surface engaging mechanisms of each housing includes a plurality of extendable appendages, each of which is radially extendable relative to the operatively associated hub portion between a retracted position and a radially extended position. The robotic vehicle also includes at least three selectively extendable members extending between the forward and rear housings, for selectively changing the distance between the forward and rear housings to effect movement of the robotic vehicle.

  8. Robotic vehicle

    DOEpatents

    Box, W. Donald (Oak Ridge, TN)

    1997-01-01

    A robotic vehicle for travel through a conduit. The robotic vehicle includes forward and rear housings each having a hub portion, and each being provided with surface engaging mechanisms for selectively engaging the walls of the conduit such that the housings can be selectively held in stationary positions within the conduit. The surface engaging mechanisms of each housing includes a plurality of extendable appendages, each of which is radially extendable relative to the operatively associated hub portion between a retracted position and a radially extended position. The robotic vehicle also includes at least three selectively extendable members extending between the forward and rear housings, for selectively changing the distance between the forward and rear housings to effect movement of the robotic vehicle.

  9. Synergistic TRAIL sensitizers from Barleria alluaudii and Diospyros maritima.

    PubMed

    Whitson, Emily L; Sun, Han; Thomas, Cheryl L; Henrich, Curtis J; Sayers, Thomas J; McMahon, James B; Griesinger, Christian; McKee, Tawnya C

    2012-03-23

    Barleria alluaudii and Diospyros maritima were both investigated as part of an ongoing search for synergistic TRAIL (tumor necrosis factor-?-related apoptosis-inducing ligand) sensitizers. As a result of this study, two naphthoquinone epoxides, 2,3-epoxy-2,3-dihydrolapachol (1) and 2,3-epoxy-2,3-dihydro-8-hydroxylapachol (2), both not previously isolated from natural sources, and the known 2-methylanthraquinone (3) were identified from B. alluaudii. Time-dependent density functional theory (TD-DFT) calculations of electronic circular dichroism (ECD) spectra were utilized to establish the absolute configuration of 1 and 2. Additionally, five known naphthoquinone derivatives, maritinone (4), elliptinone (5), plumbagin (6), (+)-cis-isoshinanolone (7), and ethylidene-6,6'-biplumbagin (8), were isolated from D. maritima. Compounds 1, 2, and 4-6 showed varying levels of synergy with TRAIL. Maritinone (4) and elliptinone (5) showed the highest synergistic effect, with more than a 3-fold increase in activity observed with TRAIL than with compound alone. PMID:22313254

  10. Synergistic TRAIL sensitizers from Barleria alluaudii and Diospyros maritima#

    PubMed Central

    Whitson, Emily L.; Sun, Han; Thomas, Cheryl L.; Henrich, Curtis J.; Sayers, Thomas J.; McMahon, James B.; Griesinger, Christian; McKee, Tawnya C.

    2012-01-01

    Barleria alluaudii and Diospyros maritima were both investigated as part of an ongoing search for synergistic TRAIL (tumor necrosis factor-?-related apoptosis-inducing ligand) sensitizers. As a result of this study, two naphthoquinone epoxides, 2,3-epoxy-2,3-dihydrolapachol (1) and 2,3-epoxy-2,3-dihydro-8-hydroxylapachol (2), both not previously isolated from natural sources, and the known 2-methyl anthraquinone (3) were identified from B. alluaudii. Time-dependent density functional theory (TD-DFT) calculations of electronic circular dichroism (ECD) spectra were utilized to establish the absolute configuration of 1 and 2. Additionally, five known naphthoquinone derivatives, maritinone (4), elliptinone (5), plumbagin (6), (+)-cis-isoshinanolone (7), and ethylidene-6,6?-biplumbagin (8) were isolated from D. maritima. Compounds 1, 2, and 4–6 showed varying levels of synergy with TRAIL. Maritinone (4) and elliptinone (5) showed the highest synergistic effect, with more than a three-fold increase in activity observed with TRAIL than with compound alone. PMID:22313254

  11. Changes of Cardiac Function During Ultradistance Trail Running.

    PubMed

    Jouffroy, Romain; Caille, Vincent; Perrot, Stéphane; Vieillard-Baron, Antoine; Dubourg, Olivier; Mansencal, Nicolas

    2015-10-15

    Previous studies have noted reversible cardiac dysfunction during marathon races, but few data are available concerning ultradistance trail running. The aim of this study was to assess echocardiographic parameters during ultradistance trail running. We performed an observational study in 66 participants to the 80-km Ecotrail of Paris Ile de France. All subjects had echocardiographic examinations before the race and on arrival, and 28 of them underwent serial echocardiographic examinations during the race (21 and 53 km). A single experienced physician performed all echocardiographic examinations, and the same protocol was always used (conventional 2-dimensional and Doppler left ventricular parameters and longitudinal strain). All echocardiographic parameters of left ventricular (LV) systolic function were significantly decreased on arrival (p ?0.002). A significant reduction of LV systolic function was observed in 48% of study subjects on arrival. No significant modification was observed at 21 or at 53 km, and only global longitudinal strain was significantly decreased (p = 0.0008). At arrival, mitral E/A ratio and average mitral tissue Doppler imaging e' wave were significantly decreased (p = 0.0001 and p = 0.0004, respectively), but these changes were observed from 21 km. In conclusion, ultradistance trail running can lead to abnormalities of LV systolic and diastolic functions in amateur runners. Diastolic dysfunction arises earlier than systolic dysfunction. Left ventricular systolic dysfunction occurred in 48% of the study subjects and was detected early by assessment of longitudinal strain. PMID:26294134

  12. Chemical trail marking and following by caterpillars ofMalacosoma neustria.

    PubMed

    Peterson, S C

    1988-03-01

    Chemical trail marking and following by gregarious caterpillars,Malacosoma neustria L. (Lepidoptera: Lasiocampidae), was studied in the laboratory. As in other species ofMalacosoma, larvae deposit a trail pheromone from a sternal secretory site when searching the host for food. Larvae in the vanguard of foraging columns establish chemical trails as they explore new territory. Marking behavior diminishes as successive unfed foragers utilize the trail. These exploratory trails are subsequently overmarked by fed larvae returning to the tent. Other foragers follow the trails of fed larvae in preference to trails of unfed larvae. Thus, like the eastern tent caterpillar,M. americanum, successful foragers ofM. neustria recruit colony-mates to feeding sites. The chemical activity of both recruitment and exploratory trails degrades slowly, suggesting that the trail pheromone ofM. neustria is a nonvolatile substance. Caterpillars ofM. neustria readily follow the nonvolatile trail pheromone which has been identified fromM. americanum, 5?-cholestane-3,24-dione. PMID:24276133

  13. Retrofiting survivability of military vehicles

    SciTech Connect

    Canavan, Gregory H

    2009-01-01

    In Iraq the terrain was such that vehicles could be distributed horizontally, which reduced the effectiveness of mines. In the mountainous terrain of Pakistan and Afghanistan vehicles are forced to use the few, passable roads, which are dirt and easily seeded with plentiful, cheap, intelligent mines. It is desirable to reduce the losses to such mines, preferably by retrofit means that do not greatly increase weight or cost or reduce maneuverability. V-bottom vehicles - A known approach to reducing vulnerability is the Buffalo, a large vehicle developed by South Africa to address mine warfare. It has large tires, high axles, and a reinforced, v-shaped bottom that deflects the blast from explosions below. It is developed and tested in combat, but is expensive and has reduced off-road mobility. The domestic MRAP has similar cost and mobility issue. The addition of v-shaped blast deflectors to vehicles such as Humvees could act much as the deflector on a Buffalo, but a Humvee is closer to the ground, so the explosive's expansion would be reduced. The deflector would also reduce a Humvee's clearance for rough terrain, and a deflector of adequate thickness to address the blast by itself could further increase cost and reduce mobility. Reactive armor is developed and has proven effective against shaped and explosive charges from side or top attack. It detects their approach, detonates, and defeats them by interfering with jet formation. If the threat was a shaped charge from below, they would be a logical choice. But the bulk of the damage to Humvees appears to be from the blast from high explosive mines for which the colliding shock from reactive armor could increase that from the explosive. Porous materials such as sand can strongly attenuate the kinetic energy and pressure of a strong shock. Figure 1 shows the kinetic energy (KE), momentum (Mu), velocity (u), and mass (M) of a spherically expanding shock as functions of radius for a material with a porosity of 0.5. Over the range from 0.5 to 4.5 cm the shock KE is attenuated by a factor of {approx}70, while its momentum is changed little. The shock and particle velocity falls by a factor of 200 while the mass increases by a factor of 730. In the limit of very porous media u {approx} 1/M, so KE {approx} 1/M, which falls by a factor of {approx}600, while momentum Mu does not change at all. Figure 2 shows the KE, Mu, u, and M for a material with a porosity of 1.05, for which the KE changes little. In the limit of media of very low porosity, u {approx} 1/{radical}M, so KE is constant while Mu {approx} {radical}M, which increases by a factor of 15. Thus, if the goal is to reduce the peak pressure from strong explosions below, very porous materials, which strongly reduce pressure but do not increase momentum, are preferred to non-porous materials, which amplify momentum but do not decrease pressure. These predictions are in qualitative accord with the results of experiments at Los Alamos in which projectiles from high velocity, large caliber cannons were stopped by one to two sandbags. The studies were performed primarily to determine the effectiveness of sand in stopping fragments of various sizes, but could be extended to study sand's effectiveness in attenuating blast pressure. It would also be useful to test the above predictions on the effectiveness of media with higher porosity. Water barriers have been discussed but not deployed in previous retrofit survivability studies for overseas embassies. They would detect the flash from the mine detonation below, trigger a thin layer of explosive above a layer of water, and drive water droplets into the approaching blast wave. The blast loses energy in evaporating the droplets and loses momentum in slowing them. Under favorable conditions that could attenuate the pressure in the blast enough to prevent the penetration or disruption of the vehicle. However, such barriers would depend on prompt and reliable detonation detection and water droplet dispersal, which have not been tested. There is a large literature on the theoretical effec

  14. Reactive oxygen species contribute to TRAIL receptors upregulation; the mechanism for PH II-7 augmenting TRAIL induced apoptosis in leukemia cells.

    PubMed

    Peng, Hongwei; Yuan, Xiangfei; Luo, Shiwen; Li, Fei; Wei, Xiaohua; Ye, Zhou; Xiong, Dongsheng

    2015-01-01

    Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can selectively induce apoptosis in cancer cells and is verified to be effective in various cancers. However, a variety of cancer cells are found to be resistant to TRAIL and the mechanisms are largely unknown. Moreover, multidrug resistance to traditional chemotherapeutic agents still remains a tough problem in clinical practice. Fortunately, our previous work proved the ability of PH II-7 in overcoming MDR phenotype through reactive oxygen species production in K562 and its MDR counterpart K562/A02 cells. Additionally, we further explored its potential in augmenting TRAIL induced apoptosis in cancer cells with various tissue origins. Our results showed PH II-7 up-regulated DR4/DR5 expression and augment TRAIL cytotoxicity through reactive oxygen species production, which provide a solid foundation for TRAIL in combination with PH II-7 in future clinical application. PMID:25446561

  15. AMELIA CESTOL Test: Acoustic Characteristics of Circulation Control Wing with Leading-and Trailing-Edge Slot Blowing

    NASA Technical Reports Server (NTRS)

    Horne, Clifton; Burnside, Nathan J.

    2013-01-01

    Aeroacoustic measurements of the 11 % scale full-span AMELIA CESTOL model with leading- and trailing-edge slot blowing circulation control (CCW) wing were obtained during a recent test in the Arnold Engineering Development Center 40- by 80-Ft. Wind Tunnel at NASA Ames Research Center, Sound levels and spectra were acquired with seven in-flow microphones and a 48-element phased microphone array for a variety of vehicle configurations, CCW slot flow rates, and forward speeds, Corrections to the measurements and processing are in progress, however the data from selected configurations presented in this report confirm good measurement quality and dynamic range over the test conditions, Array beamform maps at 40 kts tunnel speed show that the trailing edge flap source is dominant for most frequencies at flap angles of 0deg and 60deg, The overall sound level for the 60deg flap was similar to the 0deg flap for most slot blowing rates forward of 90deg incidence, but was louder by up to 6 dB for downstream angles, At 100 kts, the in-flow microphone levels were louder than the sensor self-noise for the higher blowing rates, while passive and active background noise suppression methods for the microphone array revealed source levels as much as 20 dB lower than observed with the in-flow microphones,

  16. Implementation of a Trailing-Edge Flap Analysis Model in the NASA Langley CAMRAD.MOD1/Hires Program

    NASA Technical Reports Server (NTRS)

    Charles, Bruce

    1999-01-01

    Continual advances in rotorcraft performance, vibration and acoustic characteristics are being sought by rotary-wing vehicle manufacturers to improve efficiency, handling qualities and community noise acceptance of their products. The rotor system aerodynamic and dynamic behavior are among the key factors which must be addressed to meet the desired goals. Rotor aerodynamicists study how airload redistribution impacts performance and noise, and seek ways to achieve better airload distribution through changes in local aerodynamic response characteristics. One method currently receiving attention is the use of trailing-edge flaps mounted on the rotor blades to provide direct control of a portion of the spanwise lift characteristics. The following work describes the incorporation of a trailing-edge flap model in the CAMRAD.Mod1/FHUS comprehensive rotorcraft analysis code. The CAM-RAD.Mod1/HIRES analysis consists of three separate executable codes. These include the comprehensive trim analysis, CAMRAD.Mod1, the Indicial Post-Processor, IPP, for high resolution airloads, and AIRFOIL, which produces the rotor airfoil tables from input airfoil section characteristics. The modifications made to these components permitting analysis of flapped rotor configurations are documented herein along with user instructions detailing the new input variables and operational notes.

  17. Survey of techniques for reduction of wind turbine blade trailing edge noise.

    SciTech Connect

    Barone, Matthew Franklin

    2011-08-01

    Aerodynamic noise from wind turbine rotors leads to constraints in both rotor design and turbine siting. The primary source of aerodynamic noise on wind turbine rotors is the interaction of turbulent boundary layers on the blades with the blade trailing edges. This report surveys concepts that have been proposed for trailing edge noise reduction, with emphasis on concepts that have been tested at either sub-scale or full-scale. These concepts include trailing edge serrations, low-noise airfoil designs, trailing edge brushes, and porous trailing edges. The demonstrated noise reductions of these concepts are cited, along with their impacts on aerodynamic performance. An assessment is made of future research opportunities in trailing edge noise reduction for wind turbine rotors.

  18. Hetero-modification of TRAIL trimer for improved drug delivery and in vivo antitumor activities

    PubMed Central

    Pan, Li-Qiang; Zhao, Wen-Bin; Lai, Jun; Ding, Ding; Wei, Xiao-Yue; Li, Yang-Yang; Liu, Wen-Hui; Yang, Xiao-Yue; Xu, Ying-Chun; Chen, Shu-Qing

    2015-01-01

    Poor pharmacokinetics and resistance within some tumor cell lines have been the major obstacles during the preclinical or clinical application of TRAIL (tumor-necrosis-factor (TNF)-related apoptosis-inducing ligand). The half-life of TRAIL114-281 (114 to 281 amino acids) was revealed to be no more than 30?minutes across species. Therefore maleimido activated PEG (polyethylene glycol) and MMAE (Monomethyl Auristatin E) were applied to site-specifically conjugate with the mutated cysteines from different monomers of TRAIL successively, taking advantage of steric effects involved within TRAIL mutant conjugations. As a result, TRAIL trimer was hetero-modified for different purposes. And the resulting PEG-TRAIL-vcMMAE conjugate exhibited dramatically improved half-life (11.54?h), favourable in vivo targeting capability and antitumor activities while no sign of toxicity in xenograft models, suggesting it’s a viable therapeutic and drug delivery strategy. PMID:26445897

  19. Autonomous vehicles

    SciTech Connect

    Meyrowitz, A.L.; Blidberg, D.R.; Michelson, R.C.

    1996-08-01

    There are various kinds of autonomous vehicles (AV`s) which can operate with varying levels of autonomy. This paper is concerned with underwater, ground, and aerial vehicles operating in a fully autonomous (nonteleoperated) mode. Further, this paper deals with AV`s as a special kind of device, rather than full-scale manned vehicles operating unmanned. The distinction is one in which the AV is likely to be designed for autonomous operation rather than being adapted for it as would be the case for manned vehicles. The authors provide a survey of the technological progress that has been made in AV`s, the current research issues and approaches that are continuing that progress, and the applications which motivate this work. It should be noted that issues of control are pervasive regardless of the kind of AV being considered, but that there are special considerations in the design and operation of AV`s depending on whether the focus is on vehicles underwater, on the ground, or in the air. The authors have separated the discussion into sections treating each of these categories.

  20. Detection of Water Hazards for Autonomous Robotic Vehicles

    NASA Technical Reports Server (NTRS)

    Matthes, Larry; Belluta, Paolo; McHenry, Michael

    2006-01-01

    Four methods of detection of bodies of water are under development as means to enable autonomous robotic ground vehicles to avoid water hazards when traversing off-road terrain. The methods involve processing of digitized outputs of optoelectronic sensors aboard the vehicles. It is planned to implement these methods in hardware and software that would operate in conjunction with the hardware and software for navigation and for avoidance of solid terrain obstacles and hazards. The first method, intended for use during the day, is based on the observation that, under most off-road conditions, reflections of sky from water are easily discriminated from the adjacent terrain by their color and brightness, regardless of the weather and of the state of surface waves on the water. Accordingly, this method involves collection of color imagery by a video camera and processing of the image data by an algorithm that classifies each pixel as soil, water, or vegetation according to its color and brightness values (see figure). Among the issues that arise is the fact that in the presence of reflections of objects on the opposite shore, it is difficult to distinguish water by color and brightness alone. Another issue is that once a body of water has been identified by means of color and brightness, its boundary must be mapped for use in navigation. Techniques for addressing these issues are under investigation. The second method, which is not limited by time of day, is based on the observation that ladar returns from bodies of water are usually too weak to be detected. In this method, ladar scans of the terrain are analyzed for returns and the absence thereof. In appropriate regions, the presence of water can be inferred from the absence of returns. Under some conditions in which reflections from the bottom are detectable, ladar returns could, in principle, be used to determine depth. The third method involves the recognition of bodies of water as dark areas in short-wavelength infrared (SWIR) images. This method is based on the fact, well known among experts in remote sensing, that water bodies of any appreciable depth appear very dark in near-infrared, overhead imagery. Even under a thick layer of marine fog, SWIR illumination is present. Hence, this method may work even in the presence of clouds, though it is unlikely to work at night. Snow and ice also exhibit very strong absorption at wavelengths greater than about 1.4 m. Hence, the wavelength range of about 1.5 to 1.6 m might be useable in this method for recognizing water, snow, and ice. One notable drawback of this method is that useful look-ahead distance could be limited by surface reflections. The fourth method, intended for use at night, involves the contrast between water and terrain in thermal-infrared (medium-wavelength infrared) imagery. This method is based on the fact that at night, water is usually warmer than the adjacent terrain. Look-ahead distance could be limited in this method because, for reasons not yet fully understood, water appears to darken in the thermal infrared with increasing distance.

  1. Liposome-bound TRAIL induces superior DR5 clustering and enhanced DISC recruitment in histiocytic lymphoma U937 cells.

    PubMed

    De Miguel, Diego; Gallego-Lleyda, Ana; Anel, Alberto; Martinez-Lostao, Luis

    2015-06-01

    Human Apo2-Ligand/TRAIL is a promising antitumor agent. Our group demonstrated that TRAIL was physiologically released to the extracellular medium inserted in lipid vesicles, known as exosomes. Recently we demonstrated that artificial lipid nanoparticles coated with bioactive TRAIL (LUV-TRAIL), which resemble the natural exosomes, greatly improved TRAIL activity compared with the soluble form of this death ligand and were able to induce apoptosis in hematological malignancies. In this study we have deepened the underlying mechanism of action of LUV-TRAIL in hematologic cells. Using histiocytic lymphoma U937 cells, we demonstrated that TRAIL signaling almost exclusively depends on DR5 despite these cells expressing high amounts of DR4, and proved that LUV-TRAIL's higher pro-apoptotic effect relies on its superior ability to induce DR5 clustering on cell surface, therefore enhancing DISC recruitment and triggering caspase activation more efficiently than the soluble form of TRAIL. PMID:25882551

  2. Recombinant human CD19L-sTRAIL effectively targets B cell precursor acute lymphoblastic leukemia

    PubMed Central

    Uckun, Fatih M.; Myers, Dorothea E.; Qazi, Sanjive; Ozer, Zahide; Rose, Rebecca; D’Cruz, Osmond J.; Ma, Hong

    2015-01-01

    Patients with B cell precursor acute lymphoblastic leukemia (BPL) respond well to chemotherapy at initial diagnosis; however, therapeutic options are limited for individuals with BPL who relapse. Almost all BPL cells express CD19, and we recently cloned the gene encoding a natural ligand of the human CD19 receptor (CD19L). We hypothesized that fusion of CD19L to the soluble extracellular domain of proapoptotic TNF-related apoptosis-inducing ligand (sTRAIL) would markedly enhance the potency of sTRAIL and specifically induce BPL cell apoptosis due to membrane anchoring of sTRAIL and simultaneous activation of the CD19 and TRAIL receptor (TRAIL-R) apoptosis signaling pathways. Here, we demonstrate that recombinant human CD19L-sTRAIL was substantially more potent than sTRAIL and induced apoptosis in primary leukemia cells taken directly from BPL patients. CD19L-sTRAIL effectively targeted and eliminated in vivo clonogenic BPL xenograft cells, even at femtomolar-picomolar concentrations. In mice, CD19L-sTRAIL exhibited a more favorable pharmacokinetic (PK) profile than sTRAIL and was nontoxic at doses ranging from 32 fmol/kg to 3.2 pmol/kg. CD19L-sTRAIL showed potent in vivo antileukemic activity in NOD/SCID mouse xenograft models of relapsed and chemotherapy-resistant BPL at nontoxic fmol/kg dose levels. Together, these results suggest that recombinant human CD19L-sTRAIL has clinical potential as a biotherapeutic agent against BPL. PMID:25621496

  3. P-glycoprotein-dependent resistance of cancer cells toward the extrinsic TRAIL apoptosis signaling pathway.

    PubMed

    Galski, Hanan; Oved-Gelber, Tamar; Simanovsky, Masha; Lazarovici, Philip; Gottesman, Michael M; Nagler, Arnon

    2013-09-01

    The TNF-related apoptosis-inducing ligand (TRAIL or Apo2L) preferentially cause apoptosis of malignant cells in vitro and in vivo without severe toxicity. Therefore, TRAIL or agonist antibodies to the TRAIL DR4 and DR5 receptors are used in cancer therapy. However, many malignant cells are intrinsically resistant or acquire resistance to TRAIL. It has been previously proposed that the multidrug transporter P-glycoprotein (Pgp) might play a role in resistance of cells to intrinsic apoptotic pathways by interfering with components of ceramide metabolism or by modulating the electrochemical gradient across the plasma membrane. In this study we investigated whether Pgp also confers resistance toward extrinsic death ligands of the TNF family. To this end we focused our study on HeLa cells carrying a tetracycline-repressible plasmid system which shuts down Pgp expression in the presence of tetracycline. Our findings demonstrate that expression of Pgp is a significant factor conferring resistance to TRAIL administration, but not to other death ligands such as TNF-? and Fas ligand. Moreover, blocking Pgp transport activity sensitizes the malignant cells toward TRAIL. Therefore, Pgp transport function is required to confer resistance to TRAIL. Although the resistance to TRAIL-induced apoptosis is Pgp specific, TRAIL itself is not a direct substrate of Pgp. Pgp expression has no effect on the level of the TRAIL receptors DR4 and DR5. These findings might have clinical implications since the combination of TRAIL therapy with administration of Pgp modulators might sensitize TRAIL resistant tumors. PMID:23774624

  4. Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis.

    PubMed

    Hetschko, Holger; Voss, Valerie; Seifert, Volker; Prehn, Jochen H M; Kögel, Donat

    2008-04-01

    This study was undertaken to explore the potential of new therapeutic approaches designed to reactivate cell death pathways in apoptosis-refractory gliomas and to characterize the underlying molecular mechanisms of this reactivation. Here we investigated the sensitivity of a panel of glioma cell lines (U87, U251, U343, U373, MZ-54, and MZ-18) to apoptosis induced by the death receptor ligand tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), TRAIL in combination with gamma irradiation, and TRAIL in combination with proteasome inhibitors (MG132 and epoxomicin). Analysis of these six glioma cell lines revealed drastic differences in their sensitivity to these treatments, with two of the six cell lines revealing no significant induction of cell death in response to TRAIL alone. Interestingly, the proteasome inhibitors MG132 and epoxomicin were capable of potentiating TRAIL-induced apoptosis in TRAIL-sensitive U87 and U251 cells and of reactivating apoptosis in TRAIL-resistant U343 and U373 cells. In contrast, gamma irradiation had no synergistic effects with TRAIL in the two TRAIL-resistant cell lines. RNA interference against death receptor 5 (DR5) revealed that reactivation of TRAIL-induced apoptosis by proteasome inhibitors depended on enhanced transcription and surface expression of DR5. Transient knockdown of the transcription factor GADD153/C/EBP homologous protein and application of the synthetic c-Jun N-terminal kinase inhibitor SP600125 indicated that enhanced DR5 expression occurred independently of GADD153/C/EBP homologous protein, but required activation of the c-Jun N-terminal kinase/c-Jun signaling pathway. Novel therapeutic approaches using TRAIL or agonistic TRAIL receptor antibodies in combination with proteasome inhibitors may represent a promising approach to reactivate apoptosis in therapy-resistant high-grade gliomas. PMID:18341587

  5. Modeling ant foraging: A chemotaxis approach with pheromones and trail formation.

    PubMed

    Amorim, Paulo

    2015-11-21

    We consider a continuous mathematical description of a population of ants and simulate numerically their foraging behavior using a system of partial differential equations of chemotaxis type. We show that this system accurately reproduces observed foraging behavior, especially spontaneous trail formation and efficient removal of food sources. We show through numerical experiments that trail formation is correlated with efficient food removal. Our results illustrate the emergence of trail formation from simple modeling principles. PMID:26362100

  6. Marine Drugs Regulating Apoptosis Induced by Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL).

    PubMed

    Elmallah, Mohammed I Y; Micheau, Olivier

    2015-01-01

    Marine biomass diversity is a tremendous source of potential anticancer compounds. Several natural marine products have been described to restore tumor cell sensitivity to TNF-related apoptosis inducing ligand (TRAIL)-induced cell death. TRAIL is involved during tumor immune surveillance. Its selectivity for cancer cells has attracted much attention in oncology. This review aims at discussing the main mechanisms by which TRAIL signaling is regulated and presenting how marine bioactive compounds have been found, so far, to overcome TRAIL resistance in tumor cells. PMID:26580630

  7. Static Extended Trailing Edge for Lift Enhancement: Experimental and Computational Studies

    NASA Technical Reports Server (NTRS)

    Liu, Tianshu; Montefort; Liou, William W.; Pantula, Srinivasa R.; Shams, Qamar A.

    2007-01-01

    A static extended trailing edge attached to a NACA0012 airfoil section is studied for achieving lift enhancement at a small drag penalty. It is indicated that the thin extended trailing edge can enhance the lift while the zero-lift drag is not significantly increased. Experiments and calculations are conducted to compare the aerodynamic characteristics of the extended trailing edge with those of Gurney flap and conventional flap. The extended trailing edge, as a simple mechanical device added on a wing without altering the basic configuration, has a good potential to improve the cruise flight efficiency.

  8. Population dynamics of American dog ticks (Acari: Ixodidae) along park trails

    USGS Publications Warehouse

    Carroll, J.F.; Russek-Cohen, E.; Nichols, J.D.; Hines, J.E.

    1991-01-01

    We conclude a mark-recapture study in which drag-collected ticks were removed from some park trails weekly from April to July. Weekly survival rates (probability of surviving and remaining on the trails) were significantly lower on trials used heavily by hikers, horses, and pets than on trails used less frequently. Although usage was the only obvious difference among these trails, differences in weekly survival rate estimates may be attributable to differential success in acquiring hosts. The estimated probability of capturing a host-seeking tick located along a trail on a single drag was 0.20 on the drag alone, and 0.25 including the person dragging. When routes parallel to the trails and of equal lengths were dragged immediately after sampling the trails, only .apprxeq. 5% as many ticks (including ticks on the person dragging) were found off the trails as on them. We found no evidence of reduced tick numbers on removal trails, but this result should be considered inconclusive because the power of the discerning test was low. However, the data reported here provide insights into turnover rates of the adult Dermacentor variabilis population and effectiveness of the drag as a sampling device.

  9. Marine Drugs Regulating Apoptosis Induced by Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)

    PubMed Central

    Elmallah, Mohammed I. Y.; Micheau, Olivier

    2015-01-01

    Marine biomass diversity is a tremendous source of potential anticancer compounds. Several natural marine products have been described to restore tumor cell sensitivity to TNF-related apoptosis inducing ligand (TRAIL)-induced cell death. TRAIL is involved during tumor immune surveillance. Its selectivity for cancer cells has attracted much attention in oncology. This review aims at discussing the main mechanisms by which TRAIL signaling is regulated and presenting how marine bioactive compounds have been found, so far, to overcome TRAIL resistance in tumor cells. PMID:26580630

  10. Identification of trail pheromone of larva of eastern tent caterpillarMalacosoma americanum (Lepidoptera: Lasiocampidae).

    PubMed

    Crump, D; Silverstein, R M; Williams, H J; Fitzgerald, T D

    1987-03-01

    Previous studies have shown that larvae of the eastern tent caterpillar (Malacosoma americanum F.) mark trails, leading from their tent to feeding sites on host trees, with a pheromone secreted from the posterior tip of the abdominal sternum. 5?-Cholestane-3,24-dione (1) has been identified as an active component of the trail. The larvae have a threshold sensitivity to the pheromone of 10(-11) g/mm of trail. Several related compounds elicit the trail-following response. Two other species of tent caterpillars also responded positively to the pheromone in preliminary laboratory tests. PMID:24301883

  11. Site of secretion of the trail marker of the eastern tent caterpillar.

    PubMed

    Fitzgerald, T D; Edgerly, J S

    1982-01-01

    A new site of secretion of a chemical trail marker was found on the sternum at the tip of the last abdominal segment of the larva of the eastern tent caterpillarMalacosoma americanum. Larvae marked from this site by drawing their sterna along the substrate when they extended existing trails in search of food and again when they established recruitment trails to food-finds. Differences in the quantity or quality of the marker deposited by exploring and recruiting caterpillars may account for the greater activity of the recruitment trails. PMID:24414582

  12. Unmanned ground vehicle perception using thermal infrared cameras

    NASA Astrophysics Data System (ADS)

    Rankin, Arturo; Huertas, Andres; Matthies, Larry; Bajracharya, Max; Assad, Christopher; Brennan, Shane; Bellutta, Paolo; Sherwin, Gary W.

    2011-05-01

    The ability to perform off-road autonomous navigation at any time of day or night is a requirement for some unmanned ground vehicle (UGV) programs. Because there are times when it is desirable for military UGVs to operate without emitting strong, detectable electromagnetic signals, a passive only terrain perception mode of operation is also often a requirement. Thermal infrared (TIR) cameras can be used to provide day and night passive terrain perception. TIR cameras have a detector sensitive to either mid-wave infrared (MWIR) radiation (3-5?m) or long-wave infrared (LWIR) radiation (7-14?m). With the recent emergence of high-quality uncooled LWIR cameras, TIR cameras have become viable passive perception options for some UGV programs. The Jet Propulsion Laboratory (JPL) has used a stereo pair of TIR cameras under several UGV programs to perform stereo ranging, terrain mapping, tree-trunk detection, pedestrian detection, negative obstacle detection, and water detection based on object reflections. In addition, we have evaluated stereo range data at a variety of UGV speeds, evaluated dual-band TIR classification of soil, vegetation, and rock terrain types, analyzed 24 hour water and 12 hour mud TIR imagery, and analyzed TIR imagery for hazard detection through smoke. Since TIR cameras do not currently provide the resolution available from megapixel color cameras, a UGV's daytime safe speed is often reduced when using TIR instead of color cameras. In this paper, we summarize the UGV terrain perception work JPL has performed with TIR cameras over the last decade and describe a calibration target developed by General Dynamics Robotic Systems (GDRS) for TIR cameras and other sensors.

  13. Unmanned Ground Vehicle Perception Using Thermal Infrared Cameras

    NASA Technical Reports Server (NTRS)

    Rankin, Arturo; Huertas, Andres; Matthies, Larry; Bajracharya, Max; Assad, Christopher; Brennan, Shane; Bellutta, Paolo; Sherwin, Gary W.

    2011-01-01

    The ability to perform off-road autonomous navigation at any time of day or night is a requirement for some unmanned ground vehicle (UGV) programs. Because there are times when it is desirable for military UGVs to operate without emitting strong, detectable electromagnetic signals, a passive only terrain perception mode of operation is also often a requirement. Thermal infrared (TIR) cameras can be used to provide day and night passive terrain perception. TIR cameras have a detector sensitive to either mid-wave infrared (MWIR) radiation (3-5?m) or long-wave infrared (LWIR) radiation (8-12?m). With the recent emergence of high-quality uncooled LWIR cameras, TIR cameras have become viable passive perception options for some UGV programs. The Jet Propulsion Laboratory (JPL) has used a stereo pair of TIR cameras under several UGV programs to perform stereo ranging, terrain mapping, tree-trunk detection, pedestrian detection, negative obstacle detection, and water detection based on object reflections. In addition, we have evaluated stereo range data at a variety of UGV speeds, evaluated dual-band TIR classification of soil, vegetation, and rock terrain types, analyzed 24 hour water and 12 hour mud TIR imagery, and analyzed TIR imagery for hazard detection through smoke. Since TIR cameras do not currently provide the resolution available from megapixel color cameras, a UGV's daytime safe speed is often reduced when using TIR instead of color cameras. In this paper, we summarize the UGV terrain perception work JPL has performed with TIR cameras over the last decade and describe a calibration target developed by General Dynamics Robotic Systems (GDRS) for TIR cameras and other sensors.

  14. Sodium arsenite accelerates TRAIL-mediated apoptosis in melanoma cells through upregulation of TRAIL-R1/R2 surface levels and downregulation of cFLIP expression

    SciTech Connect

    Ivanov, Vladimir N. . E-mail: vni3@columbia.edu; Hei, Tom K.

    2006-12-10

    AP-1/cJun, NF-{kappa}B and STAT3 transcription factors control expression of numerous genes, which regulate critical cell functions including proliferation, survival and apoptosis. Sodium arsenite is known to suppress both the IKK-NF-{kappa}B and JAK2-STAT3 signaling pathways and to activate the MAPK/JNK-cJun pathways, thereby committing some cancers to undergo apoptosis. Indeed, sodium arsenite is an effective drug for the treatment of acute promyelocytic leukemia with little nonspecific toxicity. Malignant melanoma is highly refractory to conventional radio- and chemotherapy. In the present study, we observed strong effects of sodium arsenite treatment on upregulation of TRAIL-mediated apoptosis in human and mouse melanomas. Arsenite treatment upregulated surface levels of death receptors, TRAIL-R1 and TRAIL-R2, through increased translocation of these proteins from cytoplasm to the cell surface. Furthermore, activation of cJun and suppression of NF-{kappa}B by sodium arsenite resulted in upregulation of the endogenous TRAIL and downregulation of the cFLIP gene expression (which encodes one of the main anti-apoptotic proteins in melanomas) followed by cFLIP protein degradation and, finally, by acceleration of TRAIL-induced apoptosis. Direct suppression of cFLIP expression by cFLIP RNAi also accelerated TRAIL-induced apoptosis in these melanomas, while COX-2 suppression substantially increased levels of both TRAIL-induced and arsenite-induced apoptosis. In contrast, overexpression of permanently active AKTmyr inhibited TRAIL-mediated apoptosis via downregulation of TRAIL-R1 levels. Finally, AKT overactivation increased melanoma survival in cell culture and dramatically accelerated growth of melanoma transplant in vivo, highlighting a role of AKT suppression for effective anticancer treatment.

  15. Combination Anticancer Nanopreparations of Novel Proapoptotic Drug, TRAIL and siRNA

    NASA Astrophysics Data System (ADS)

    Riehle, Robert D.

    Development of drugs for the treatment of cancer is a challenging endeavor often hindered by the solubility and distribution of the drug in the body. Drug delivery systems have been used for many years to overcome these issues. Polyethylene glycol-phosphatidylethanolamine (PEG-PE) micelles in particular have shown utility as a nanosized drug delivery vehicle capable of incorporating poorly soluble drugs and preferentially delivering them to the tumor. Addition of PEG polymers to the surface prolongs the half-life of the particle in the blood by evading clearance by the reticuloendothelial system (RES) and increases tumor accumulation through the utilization of the enhanced permeability and retention (EPR) effect. Micelles have also been shown to successfully incorporate and protect modified siRNA, a notoriously challenging therapeutic to deliver. Additionally, co-delivery of multiple therapeutics in multifunctional micelles has emerged as an important area in combination therapy research. The main goal of this project was to develop a multifunctional PEG-PE micellar delivery system capable of delivering multiple therapeutics for increased anti-tumor activity. Previous studies have indicated the utility of a DM-PIT-1, a member of a class of novel PIP3-PH inhibitors, and its potential in the treatment of cancer. The PIP3-kinase (PI3K) pathway has been shown to have serious implications in cancer. Inhibiting this pathway has been shown to sensitize the cell to apoptosis. A second generation of more potent and druggable compounds has been developed based on the structure of DM- PIT-1. However, it has been difficult to develop successful compounds inhibiting PIP3 signaling while maintaining the physicochemical properties necessary for an effective drug. Many of these compounds are limited by their poor solubility and rapid clearance in vivo. Incorporating these compounds into PEG-PE micelles allows for increased solubility, prolonged half-life and tumor accumulation. The addition of TNFa-related apoptosis-inducing ligand (TRAIL) bound to the surface of the micelle creates a combination micelle with excellent cytotoxic effects. TRAIL has been shown to be an effective apoptosis inducing ligand in a variety of in vitro and in vivo studies. TRAIL receptors are preferentially expressed on many cancer cell types as compared to healthy cells making this ligand an intriguing potential therapy. The combination of TRAIL and PIP3-PH inhibitors in a micellar delivery system has the potential to create a powerful anti-cancer therapeutic. Including modified siRNA to down regulate cancer defense mechanisms can further sensitize the cell to apoptosis. siRNA delivery has been shown to be a difficult task. Rapid metabolism and clearance in the blood hinders their ability to reach the tumor. Additionally, their large size and negative charge prevents them from crossing the cell membrane to reach their location of action. Reversibly conjugating a modified siRNA to a lipid thereby creating an siRNA-S-S-PE, allows for their incorporation into PEG-PE micelles. These mixed micelles have been shown to protect the siRNA and successfully transfect cells. This study aimed to combine the aforementioned therapeutics into a multifunctional PEG-PE based micelle delivery system. Novel proapoptotic drugs targeting the PIP3-PH binding domain have been successfully incorporated into the lipid core of the micelle. These drugs were able to effectively sensitize the cell to the effects of surface-bound TRAIL. Additionally, siRNA targeting the anti-apoptotic protein survivin was shown to be incorporated into the micelles and further sensitize the tumor to the effects of the above compounds. Lastly, conjugating transferrin (TF) to the surface of the micelle was shown increase the tumor cell targeting and cytotoxicity in vitro. Critical evaluation of this system was performed along the following specific aims: (1) characterization of PIP3-PH inhibition and cytotoxicity of proapoptotic drug DM-PIT-1 and its novel analogs in vitro with and without TRAIL; (2) preparatio

  16. Analysis of the quality of hospital information systems audit trails

    PubMed Central

    2013-01-01

    Background Audit Trails (AT) are fundamental to information security in order to guarantee access traceability but can also be used to improve Health information System’s (HIS) quality namely to assess how they are used or misused. This paper aims at analysing the existence and quality of AT, describing scenarios in hospitals and making some recommendations to improve the quality of information. Methods The responsibles of HIS for eight Portuguese hospitals were contacted in order to arrange an interview about the importance of AT and to collect audit trail data from their HIS. Five institutions agreed to participate in this study; four of them accepted to be interviewed, and four sent AT data. The interviews were performed in 2011 and audit trail data sent in 2011 and 2012. Each AT was evaluated and compared in relation to data quality standards, namely for completeness, comprehensibility, traceability among others. Only one of the AT had enough information for us to apply a consistency evaluation by modelling user behaviour. Results The interviewees in these hospitals only knew a few AT (average of 1 AT per hospital in an estimate of 21 existing HIS), although they all recognize some advantages of analysing AT. Four hospitals sent a total of 7 AT – 2 from Radiology Information System (RIS), 2 from Picture Archiving and Communication System (PACS), 3 from Patient Records. Three of the AT were understandable and three of the AT were complete. The AT from the patient records are better structured and more complete than the RIS/PACS. Conclusions Existing AT do not have enough quality to guarantee traceability or be used in HIS improvement. Its quality reflects the importance given to them by the CIO of healthcare institutions. Existing standards (e.g. ASTM:E2147, ISO/TS 18308:2004, ISO/IEC 27001:2006) are still not broadly used in Portugal. PMID:23919501

  17. Ants Can Learn to Forage on One-Way Trails

    PubMed Central

    Ribeiro, Pedro Leite; Helene, André Frazão; Xavier, Gilberto; Navas, Carlos; Ribeiro, Fernando Leite

    2009-01-01

    The trails formed by many ant species between nest and food source are two-way roads on which outgoing and returning workers meet and touch each other all along. The way to get back home, after grasping a food load, is to take the same route on which they have arrived from the nest. In many species such trails are chemically marked by pheromones providing orientation cues for the ants to find their way. Other species rely on their vision and use landmarks as cues. We have developed a method to stop foraging ants from shuttling on two-way trails. The only way to forage is to take two separate roads, as they cannot go back on their steps after arriving at the food or at the nest. The condition qualifies as a problem because all their orientation cues – chemical, visual or any other - are disrupted, as all of them cannot but lead the ants back to the route on which they arrived. We have found that workers of the leaf-cutting ant Atta sexdens rubropilosa can solve the problem. They could not only find the alternative way, but also used the unidirectional traffic system to forage effectively. We suggest that their ability is an evolutionary consequence of the need to deal with environmental irregularities that cannot be negotiated by means of excessively stereotyped behavior, and that it is but an example of a widespread phenomenon. We also suggest that our method can be adapted to other species, invertebrate and vertebrate, in the study of orientation, memory, perception, learning and communication. PMID:19337369

  18. The Global and Local Characters of Mars Perihelion Cloud Trails

    NASA Astrophysics Data System (ADS)

    Clancy, R. T.; Wolff, M. J.; Smith, M. D.; Cantor, B. A.; Spiga, A.

    2014-12-01

    We present the seasonal and spatial distribution of Mars perihelion cloud trails as mapped from Mars Reconnaissance Orbiter (MRO) MARCI (Mars Color Imager) imaging observations in 2 ultraviolet and 3 visible filters. The extended 2007-2013 period of MARCI daily global image maps reveals the widespread distribution of these high altitude clouds, which are somewhat paradoxically associated with specific surface regions. They appear as longitudinally extended (300-700 km) cloud trails with distinct leading plumes of substantial ice cloud optical depths (0.02-0.2) for such high altitudes of occurrence (40-50 km, from cloud surface shadow measurements). These plumes generate small ice particles (Reff~1 to <0.2 microns) that become entrained in the strong westward mesospheric zonal wind regime of the perihelion (southern summer ) season, although the specific dynamics and cloud microphysics for these plumes are not determined. They are clearly tied to maximum surface heating on Mars, in terms of season (perihelion), local time (early afternoon), and surface latitude/albedo/elevation. The most persistent expressions of these clouds are found in association with two Valles Marineris locations (Clancy et al., 2009). However, a broader survey of MARCI observations reveals many specific regions of occurrence over Ls=200-300. Furthermore, MRO CRISM limb observations indicate a haze of such fine water ice particles characterizes the full southern hemisphere mesosphere at this time. Hence, the behavior of perihelion cloud trails appears to reflect locally elevated mesospheric water ice formation that may impact the global expression of mesospheric water ice aerosols.

  19. Computational Aeroacoustic Analysis of Slat Trailing-Edge Flow

    NASA Technical Reports Server (NTRS)

    Singer, Bart A.; Lockhard, David P.; Brentner, Kenneth S.; Khorrami, Mehdi R.; Berkman, Mert E.; Choudhari, Meelan

    2000-01-01

    An acoustic analysis based on the Ffowcs Williams and Hawkings equation was performed for a high-lift system. As input, the acoustic analysis used un- steady flow data obtained from a highly resolved, time-dependent, Reynolds-averaged Navier-Stokes calculation. The analysis strongly suggests that vor- tex shedding from the trailing edge of the slat results in a high-amplitude, high-frequency acoustic signal, similar to that which was observed in a correspond- ing experimental study of the high-lift system.

  20. The structure of trailing vortices generated by model rotor blades

    NASA Technical Reports Server (NTRS)

    Tung, C.; Pucci, S. L.; Caradonna, F. X.; Morse, H. A.

    1981-01-01

    Hot-wire anemometry to analyze the structure and geometry of rotary wing trailing vortices is studied. Tests cover a range of aspect ratios and blade twist. For all configurations, measured vortex strength correlates well with maximum blade-bound circulation. Measurements of wake geometry are in agreement with classical data for high-aspect ratios. The detailed vortex structure is similar to that found for fixed wings and consists of four well defined regions--a viscous core, a turbulent mixing region, a merging region, and an inviscid outer region. A single set of empirical formulas for the entire set of test data is described.