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Sample records for parc electronucleaire francais

  1. J-PARC Accelerator

    SciTech Connect

    Yamazaki, Yoshishige

    2008-02-21

    The Japan Proton Accelerator Research Complex (J-PARC) is under construction in Tokai site. The linac beam commissioning started last fall, while the beam commissioning of the 3-GeV Rapid-Cycling Synchrotron (RCS) will start this fall. The status of the J-PARC accelerator is reported with emphasis on the technical development accomplished for the J-PARC.

  2. Le Francais Courant: Part V, French.

    ERIC Educational Resources Information Center

    Dade County Public Schools, Miami, FL.

    Instructional objectives of the Dade County Public Schools Quinmester Program in French for use with "Le Francais Courant: Part 5" focus on the development of mastery of the basic numbering system and other grammatical structures. Structures include the formation of the present tense of the irregular verbs "vouloir,""pouvoir," and "venir,"…

  3. Le Francais Moderne: Part I, French.

    ERIC Educational Resources Information Center

    Dade County Public Schools, Miami, FL.

    Instructional objectives of the Dade County Public Schools Quinmester Program in French for use with "Le Francais Moderne: Part 1" focus on the development of vocabulary and mastery of grammatical structures. The formation of the passe compose with "avoir," object pronouns, the present tense of regular "-ir" verbs, and the irregular verbs…

  4. PARC and CUL7 form atypical cullin RING ligase complexes.

    PubMed

    Skaar, Jeffrey R; Florens, Laurence; Tsutsumi, Takeya; Arai, Takehiro; Tron, Adriana; Swanson, Selene K; Washburn, Michael P; DeCaprio, James A

    2007-03-01

    CUL7 and the p53-associated, PARkin-like cytoplasmic protein (PARC) were previously reported to form homodimers and heterodimers, the first demonstration of cullin dimerization. Although a CUL7-based SKP1/CUL1/F-box (SCF)-like complex has been observed, little is known about the existence of a PARC-based SCF-like complex and how PARC interacts with CUL7-based complexes. To further characterize PARC-containing complexes, we examined the ability of PARC to form an SCF-like complex. PARC binds RBX1 and is covalently modified by NEDD8, defining PARC as a true cullin. However, PARC fails to bind SKP1 or F-box proteins, including the CUL7-associated FBXW8. To examine the assembly of PARC- and CUL7-containing complexes, tandem affinity purification followed by multidimensional protein identification technology were used. Multidimensional protein identification technology analysis revealed that the CUL7 interaction with FBXW8 was mutually exclusive of CUL7 binding to PARC or p53. Notably, although heterodimers of CUL7 and PARC bind p53, p53 is not required for the dimerization of CUL7 and PARC. The observed physical separation of FBXW8 and PARC is supported functionally by the generation of Parc-/-, Fbxw8-/- mice, which do not show exacerbation of the Fbxw8-/- phenotype. Finally, all of the PARC and CUL7 subcomplexes examined exhibit E3 ubiquitin ligase activity in vitro. Together, these findings indicate that the intricate assembly of PARC- and CUL7-containing complexes is highly regulated, and multiple subcomplexes may exhibit ubiquitin ligase activity. PMID:17332328

  5. Systematic in J-PARC/Hyper-K

    SciTech Connect

    Minamino, Akihiro

    2015-05-15

    The Hyper-Kamiokande (Hyper-K) detector is a next generation underground water Chrenkov detector. The J-PARC to Hyper-K experiment has good potential for precision measurements of neutrino oscillation parameters and discovery reach for CP violation in the lepton sector. With a total exposure of 10 years to a neutrino beam produced by the 750 kW J-PARC proton synchrotron, it is expected that the CP phase δ can be determined to better than 18 degree for all possible values of δ if sin{sup 2} 2θ{sub 13} > 0.03 and the mass hierarchy is known. Control of systematic uncertainties is critical to make maximum use of the Hyper-K potential. Based on learning from T2K experience, a strategy to reduce systematic uncertainties in J-PARC/Hyper-K are developed.

  6. La culture politique du Mouvement Quebec Francais [The Political Culture of the "French Quebec Movement"].

    ERIC Educational Resources Information Center

    Turcotte, Denis

    This study of the "Mouvement Quebec Francais (MQF)" covers the period from March 1971 through Spring 1974. The fundamental postulate of the study is that if the political culture is internalized by individuals, it is at the same time borne by groups. The study of groups represents, therefore, a good vehicle to reveal the most significant…

  7. The Lycee Francais in New York: A Showcase for the French-Speaking Community

    ERIC Educational Resources Information Center

    Michel, Florence

    2004-01-01

    In New York they say that the architecture of the new "Lycee francais" (serving French students from kindergarten through upper secondary education) was inspired by the rationalism of Descartes. What is beyond doubt, however, is that the design and materials chosen by the American firm of architects, "Polshek Partnership Architects," which…

  8. A PARC system for terminal docking

    NASA Technical Reports Server (NTRS)

    Gilbert, John A.; Bankston, Cheryl D.

    1991-01-01

    A Panoramic viewing system for Automated Rendezvous and Capture (PARC) has been proposed as a visual information feedback system for terminal docking/berthing. The system relies on a unique Panoramic Annular Lens (PAL) which captures an image of its surroundings in real time. This paper describes the evolution of the PAL along with technical details of its imaging capabilities. Several examples are given of radial metrology, where PAL imaging systems are used to perform visual inspections and measurements. Digital image acquisition and processing techniques, used to interpret various features appearing in the images and to transform images for improved human viewing, are also included. These discussions are followed by a potential application for PARC involving berthing of active and passive mechanical assemblies associated with Space Station Freedom.

  9. Neutrino Physics at J-PARC

    NASA Astrophysics Data System (ADS)

    Friend, Megan

    The physics motivation, status, and prospects of currently running and proposed neutrino experiments at J-PARC are shown. This includes the currently running T2K (Tokai-to-Kamioka) long-baseline neutrino oscillation experiment and a proposed Sterile Neutrino Search. The currently running T2K experiment detects oscillated ν μ to ν e appearance and unoscillated ν μ to ν μ disappearance neutrino events from an off-axis beam of primarily muon neutrinos produced at J-PARC. Propagated neutrinos are detected in a Near Detector complex, which sits 280 m from the neutrino source and is used to constrain the neutrino flux and measure neutrino cross sections, and in the Super-Kamiokande (SK) far detector, a 22.5 kT fiducial volume water Cherenkov detector with excellent performance in sub-GeV ν e/ν μ particle ID that sits 295 km from the neutrino source and is used to monitor neutrino oscillations. T2K has recently released a series of very interesting and important results, including the world's first definitive observation of neutrino appearance (ν e appearance from a ν μ beam), an observation which was made with only 8% of the proposed total data. T2K has continued to accumulate data since releasing these results, and has many exciting prospects, including potentially having sensitivity to show a first hint of CP violation in the lepton sector. These T2K recent results and future prospects will be shown. A brief overview of the prospects of a proposed future Sterile Neutrino Search, which plans to utilize the J-PARC Materials and Life Science Experimental Facility to initially search for sterile neutrinos with a large mass splitting, will also be shown.

  10. Spin Physics at J-PARC

    NASA Astrophysics Data System (ADS)

    Kumano, S.

    2016-02-01

    Spin-physics projects at J-PARC are explained by including future possibilities. J-PARC is the most-intense hadron-beam facility in the high-energy region above multi-GeV, and spin physics will be investigated by using secondary beams of kaons, pions, neutrinos, muons, and antiproton as well as the primary-beam proton. In particle physics, spin topics are on muon g ‑ 2, muon and neutron electric dipole moments, and time-reversal violation experiment in a kaon decay. Here, we focus more on hadron-spin physics as for future projects. For example, generalized parton distributions (GPDs) could be investigated by using pion and proton beams, whereas they are studied by the virtual Compton scattering at lepton facilities. The GPDs are key quantities for determining the three-dimensional picture of hadrons and for finding the origin of the nucleon spin including partonic orbital-angular-momentum contributions. In addition, polarized parton distributions and various hadron spin topics should be possible by using the high-momentum beamline. The strangeness contribution to the nucleon spin could be also investigated in principle with the neutrino beam with a near detector facility.

  11. Design concept for the microwave interrogation structure in PARCS

    NASA Technical Reports Server (NTRS)

    Dick, G. J.; Klipstein, W. M.; Heavner, T. P.; Jefferts, S. R.

    2002-01-01

    In this paper we will describe key aspects of the conceptual design of the microwave interrogation structure in the laser-cooled cesium frequency standard that is part of the Primary Atomic Reference Clock in Space (PARCS) experiment.

  12. PARC code validation for propulsion flows

    NASA Astrophysics Data System (ADS)

    Cooper, G. K.; Garrard, G. D.; Phares, W. J.

    1989-01-01

    Validation/calibration of the PARC Navier-Stokes computer program for flows typical of turbine engine and rocket motor testing at the Arnold Engineering Development Center has been performed for a number of fundamental test cases. Laminar and turbulent flow simulations for a flat plate with zero pressure gradient have been compared with solutions of the boundary-layer equations with good-to-excellent results. These test cases examined effects of grid spacing in both the streamwise and cross-stream directions, compressibility, and heat transfer. The laminar flow simulations with a new artificial viscosity model were in excellent agreement with the boundary-layer code results; the turbulent simulations with a Baldwin- and Lomax-style turbulence model compared less favorably with some cases showing a 10-percent error in skin friction. The near wake of turbulent supersonic jet was also simulated and compared very well with experimental data.

  13. J-PARC Status, Nuclear and Particle Physics

    SciTech Connect

    Sato, Susumu

    2011-06-01

    J-PARC accelerator research complex, consisting of LINAC, RCS and MR synchrotron, has successfully produced neutron, muons, kaons, and neutrinos by steady commissioning since November 2006. There are three experimental facilities, and for nuclear and particle physics, nine experiments are approved in a hadron physics facility, and one experiment is approved in a neutrino physics facility. Those experiments and status of J-PARC are described in this paper.

  14. RELIEF: Revue de linguistique et d'enseignement du francais (Review of Linguistics and French Language Instruction), 1994.

    ERIC Educational Resources Information Center

    Mahler, M., Ed.; Haillet, P., Ed.

    1994-01-01

    Contains five articles, all in French, reporting research on French second language instruction. "Francophonie et francais langue seconde a l'oral: quel(s) culture(s), quelles methodes?" (Francophony and Spoken French as a Second Language: What Cultures(s), What Method(s) (D. Issa-Sayegh) discusses the content and structure of a university course…

  15. RELIEF: Revue de linguistique et d'enseignement du francais (Review of Linguistics and French Language Instruction), 1991-1993.

    ERIC Educational Resources Information Center

    Haillet, P., Ed.; And Others

    1993-01-01

    This document consists of the first two issues of the journal RELIEF. Each issue contains four articles. All articles deal with French second language instruction: (1) "Utiliser la presse ecrite en classe de francais-langue seconde (Using the Print Media in French Second Language Class)" (H. Canto); (2) "Une lecon de grammaire facile a concevoir,…

  16. Features Of The J-PARC Linac

    SciTech Connect

    Kobayashi, Tetsuya

    2011-06-01

    Japan Proton Accelerator Research Complex (J-PARC) will be one of the highest intensity proton accelerators in the world aiming to realize 1 MW class of the beam power. The accelerator consists of a 400-MeV linac, a 3-GeV rapid-cycling synchrotron (RCS) and a main ring synchrotron (MR), and the accelerated beam is applied to several experimental facilities. The linac, which is the injector for the RCS, has about 50 cavity modules to accelerate the beam up to 400 MeV. The acceleration field error in all of them should be within {+-}1% in amplitude and {+-}1 degree in phase because the momentum spread of the RCS injection beam is required to be within 0.1%. For the cavity field stabilization, a high-stable optical signal distribution system is used as the RF reference, and sophisticated digital feedback and feed-forward system is working well in the low level RF control system. Consequently the providing beam to the RCS is very stable, and the beam commissioning and the experiments of the application facilities have been progressed steadily.

  17. Parcs:. a Laser-Cooled Atomic Clock in Space

    NASA Astrophysics Data System (ADS)

    Heavner, T. P.; Hollberg, L. W.; Jefferts, S. R.; Robinson, H. G.; Sullivan, D. B.; Walls, F. L.; Ashby, N.; Klipstein, W. M.; Maleki, L.; Seidel, D. J.; Thompson, R. J.; Wu, S.; Young, L.; Mattison, E. M.; Vessot, R. F. C.; Demarchi, A.

    2002-04-01

    This paper describes progress toward the development of a Primary Atomic Reference Clock in Space (PARCS) and reviews the scientific and technical objectives of the PARCS mission. PARCS is a collaborative effort involving the National Institute of Standards and Technology (NIST), the University of Colorado, the Jet Propulsion Laboratory (JPL), the Harvard Smithsonian Center for Astrophysics (SAO) and the Politecnico di Torino. Space systems for this experiment include a laser-cooled cesium atomic clock and a GPS frequency-comparison and orbit determination system, along with a hydrogen maser that serves as both a local oscillator for the cesium clock and a reference against which certain tests of gravitational theory can be made. In the microgravity environment of the International Space Station (ISS), cesium atoms can be launched more slowly through the clock's microwave cavity, thus significantly reducing a number of troubling effects (including several critical systematic effects), so clock performance can be substantially improved beyond that achieved on earth.

  18. J-PARC E19 Experiment: Pentaquark Θ+ Search in Hadronic Reaction at J-PARC

    NASA Astrophysics Data System (ADS)

    Takahashi, Tomonori N.; Adachi, Satoshi; Agnello, Michelangelo; Ajimura, Shuhei; Aoki, Kanae; Bhang, Hyoung Chan; Bassalleck, Bernd; Botta, Elena; Bufalino, Stefania; Chiga, Nobuyuki; Ekawa, Hiroyuki; Evtoukhovitch, Petr; Feliciello, Alessandro; Fujioka, Hiroyuki; Hayakawa, Shuhei; Hiruma, Fumiki; Honda, Ryotaro; Hosomi, Kenji; Ichikawa, Yudai; Ieiri, Masaharu; Igarashi, Youichi; Imai, Ken'ichi; Ishibashi, Naoya; Ishimoto, Shigeru; Itahashi, Kenta; Iwasaki, Ruri; Joo, Chang Woo; Kanatsuki, Shunsuke; Kim, Mi Jung; Kim, Sun Ji; Kiuchi, Ryuta; Koike, Takeshi; Komatsu, Yusuke; Vasil'evich Kulikov, Vyacheslav; Marcello, Simonetta; Masumoto, Shinichi; Matsumoto, Yuki; Matsuoka, Kenji; Miwa, Koji; Moritsu, Manabu; Nagae, Tomofumi; Naruki, Megumi; Niiyama, Masayuki; Noumi, Hiroyuki; Nozawa, Yuki; Ota, Ryosuke; Ozawa, Kyoichiro; Saito, Naohito; Sakaguchi, Atsushi; Sako, Hiroyuki; Samoilov, Valentin; Sato, Misako; Sato, Susumu; Sato, Yoshinori; Sawada, Shin'ya; Sekimoto, Michiko; Shirotori, Kotaro; Sugimura, Hitoshi; Suzuki, Shoji; Takahashi, Hitoshi; Takahashi, Toshiyuki; Tamura, Hirokazu; Tanaka, Toshiyuki; Tanida, Kiyoshi; Tokiyasu, Atsushi O.; Tomida, Natsuki; Tsamalaidze, Zviadi; Ukai, Mifuyu; Yagi, Kazuya; Yamamoto, Takeshi O.; Yang, Seong Bae; Yonemoto, Yoshio; Yoon, Choong Jae; Yoshida, Kotaro

    A search for the Θ+ pentaquark in the π - p to K - X reaction was performed at the J-PARC Hadron Facility. Two data samples were collected in 2010 and 2012 at π beam momenta of 1.92 and 2.0 GeV/c, respectively. No peak structure was observed in the missing mass spectra obtained from either data set. The upper limit for the production cross section averaged over the scattering-angle range of 2° to 15° in the laboratory frame was found to be 0.28 µb/sr. The decay width of the Θ+ can be directly connected to the production cross section through a theoretical calculation using an effective Lagrangian. The estimated upper limits of the width were 0.41 and 2.8 MeV for the spin-parities of 1/2+ and 1/2-, respectively.

  19. Muonium in J-PARC; from fundamental to application

    NASA Astrophysics Data System (ADS)

    Shimomura, K.

    2015-08-01

    At J-PARC, the muon science facility (MUSE) was successfully constructed in the Materials and Life Science Facility (MLF), and three scientific activities is now ongoing related muonium (Mu) from fundamental to application; 1) Mu hyperfine structure measurement (MuSEUM), 2) Ultra Slow Muon Microscope (USMM) and 3) muon g-2 and EDM measurement. Here, we will report present status of each activity.

  20. Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development.

    PubMed

    Skaar, Jeffrey R; Arai, Takehiro; DeCaprio, James A

    2005-07-01

    CUL7, a recently identified member of the cullin family of E3 ubiquitin ligases, forms a unique SCF-like complex and is required for mouse embryonic development. To further investigate CUL7 function, we sought to identify CUL7 binding proteins. The p53-associated, parkin-like cytoplasmic protein (PARC), a homolog of CUL7, was identified as a CUL7-interacting protein by mass spectrometry. The heterodimerization of PARC and CUL7, as well as homodimerization of PARC and CUL7, was confirmed in vivo. To determine the biological role of PARC by itself and in conjunction with CUL7, a targeted deletion of Parc was created in the mouse. In contrast to the neonatal lethality of the Cul7 knockout mice, Parc knockout mice were born at the expected Mendelian ratios and exhibited no apparent phenotype. Additionally, Parc deletion did not appear to affect the stability or function of p53. These results suggest that PARC and CUL7 form an endogenous complex and that PARC and CUL7 functions are at least partially nonoverlapping. In addition, although PARC and p53 form a complex, the absence of effect of Parc deletion on p53 stability, localization, and function suggests that p53 binding to PARC may serve to control PARC function. PMID:15964813

  1. High-energy hadron physics at J-PARC

    SciTech Connect

    Kumano, S.

    2008-10-13

    The J-PARC facility is near completion and experiments will start in 2009 on nuclear and particle physics projects. In this article, the J-PARC facility is introduced, and possible projects are discussed in high-energy hadron physics by using the primary proton beam of 30-50 GeV. There are proposed experiments on charm-production and Drell-Yan processes as well as single spin asymmetries for investigating quark and gluon structure of the nucleon and nuclei. Parton-energy loss could be studied in the Drell-Yan processes. There is also a proposal on hadron-mass modifications in a nuclear medium by using the proton beam. In addition, possible topics include transition from hadron to quark degrees of freedom by elastic pp scattering, color transparency by (p,2p), short-range correlation in nuclear force by (p,2pN), tensor structure functions for spin-one hadrons, fragmentation functions, and generalized partem distributions in the ERBL region although proposals are not written on these projects. If proton-beam polarization is attained, it is possible to investigate details of nucleon spin structure. In the last part of this article, our own studies are explained on partem distribution functions in connection with the J-PARC projects.

  2. Annual Report: 2014: Partners in Amphibian and Reptile Conservation (PARC)

    USGS Publications Warehouse

    Weir, Linda A.; Nanjappa, P.; Apodaca, J. J.; Williams, J.

    2015-01-01

    Partners in Amphibian and Reptile Conservation (PARC) was established in 1999 to address the widespread declines, extinctions, and range reductions of amphibians and reptiles, with a focus on conservation of taxa and habitats in North America. Amphibians and reptiles are affected by a broad range of human activities, both as incidental effects of habitat alteration and direct effects from overexploitation; these animals are also burdened by humans attitudes – that amphibians and reptiles are either dangerous or of little environmental or economic value. However, PARC members understand these taxa are important parts of our natural and cultural heritage and they serve important roles in ecosystems throughout the world. With many amphibians and reptiles classified as threatened with extinction, conservation to ensure healthy populations of these animals has never been more important. As you will see herein, PARC’s 15th anniversary has been marked with major accomplishments and an ever-increasing momentum. With your help, PARC can continue to build on its successes and protect these vital species.

  3. Performance of the PARCS Testbed Cesium Fountain Frequency Standard

    NASA Technical Reports Server (NTRS)

    Enzer, Daphna G.; Klipstein, William M.

    2004-01-01

    A cesium fountain frequency standard has been developed as a ground testbed for the PARCS (Primary Atomic Reference Clock in Space) experiment, an experiment intended to fly on the International Space Station. We report on the performance of the fountain and describe some of the implementations motivated in large part by flight considerations, but of relevance for ground fountains. In particular, we report on a new technique for delivering cooling and trapping laser beams to the atom collection region, in which a given beam is recirculated three times effectively providing much more optical power than traditional configurations. Allan deviations down to 10 have been achieved with this method.

  4. A STUDY OF POLARIZED PROTON ACCELERATION IN J-PARC.

    SciTech Connect

    LUCCIO, A.U.; BAI, M.; ROSER, T.

    2006-10-02

    We have studied the feasibility of polarized proton acceleration in rhe J-PARC accelerator facility, consisting of a 400 MeV linac, a 3 GeV rapid cycling synchrotron (RCS) and a 50 GeV synchrotron (MR). We show how the polarization of the beam can be preserved using an rf dipole in the RCS and two superconductive partial helical Siberian snakes in the MR. The lattice of the MR will be modified with the addition of quadrupoles to compensate for the focusing properties of the snakes.

  5. A Study of Polarized Proton Acceleration in J-PARC

    SciTech Connect

    Luccio, A. U.; Bai, M.; Roser, T.; Molodojentsev, A.; Ohmori, C.; Sato, H.; Hatanaka, K.

    2007-06-13

    We have studied the feasibility of polarized proton acceleration in rhe J-PARC accelerator facility, consisting of a 400 MeV linac, a 3 GeV rapid cycling synchrotron (RCS) and a 50 GeV synchrotron (MR). We show how the polarization of the beam can be preserved using an rf dipole in the RCS and two superconductve partial helical Siberian snakes in the MR. The lattice of the MR will be modified with the addition of quadrupoles to compensate for the focusing properties of the snakes.

  6. Measurement of Muonium Hyperfine Splitting at J-PARC

    NASA Astrophysics Data System (ADS)

    Tanaka, K. S.; Aoki, M.; Iinuma, H.; Ikedo, Y.; Ishida, K.; Iwasaki, M.; Ueno, Y.; Ohkubo, R.; Ogitsu, T.; Kadono, R.; Kamigaito, O.; Kawamura, N.; Kawall, D.; Kanda, S.; Kubo, K.; Kume, T.; Koda, A.; Kojima, K.; Saito, N.; Sakamoto, N.; Sasaki, K.; Shimomura, K.; Sugano, M.; Tomono, D.; Toyoda, A.; Torii, H. A.; Torikai, E.; Nagamine, K.; Nishiyama, K.; Strasser, P.; Fukao, Y.; Fujiwara, Y.; Matsuda, Y.; Mibe, T.; Miyake, Y.; Yoshida, M.

    We are planning a measurement of the ground state hyperfine structure of muonium at J-PARC/MLF. Muonium is a hydrogen-like bound state of leptons, and its is a good probe for testing QED theory. The muon mass and magnetic moment which are fundamental constants of muon have been so far determined by the ground state hyperfine structure of muonium (muonium HFS) experiment at LAMPF [1]. To estimte the systematic uncertainties in our experiment, we developed a simulation tool to estimate the systematic uncertainties from several sources in our experiment. The progress of estimation of uncertainties by this tool, development of detectors, and NMR probes are presented.

  7. L'enseignement modulaire et le laboratoire de langues: conception et experimentation d'un nouveau cours de francais oral au Centre d'anglais et de francais, Universite McGill (Modular Instruction and the Language Laboratory: Conception and Experimentation with a New Course in Oral French at the English and French Center, McGill University).

    ERIC Educational Resources Information Center

    Legoux, Marie-Noelle

    1980-01-01

    A modular-type course in French was developed at the "Centre d'anglais et de francais" at McGill University (Montreal) to meet the needs of incoming students who were lacking skills in listening and oral expression. The course is composed of eight modules a semester, each module corresponding to 15 to 20 hours work on the student's part. The…

  8. L'enseignement du francais en Republique Federale d'Allemagne (The Teaching of French in the Federal Republic of Germany). L'enseignement du francais dans les classes terminales des lycees allemands (The Teaching of French in the Final Year in German Schools).

    ERIC Educational Resources Information Center

    Abel, Fritz; Lang, Jurgen

    Two papers describe two aspects of French foreign language instruction in West Germany. The first, "L'enseignement du francais en Republique Federale d'Allemagne" by Abel, deals with the institutional framework for French instruction in West Germany. A discussion of the instructional situation looks first at the history of French instruction since…

  9. Proposal to Participate in J-Parc KL Experiment

    SciTech Connect

    Campbell, Myron; Tecchio, Monica

    2013-02-03

    During the previous grant period we have been working on the J-PARC KL E14 (KOTO) experiment with the goal to discover and measure the rate of the rare decay neutral kaons to a pion and two neutrinos. This CP-violating flavor changing neutral current decay proceeds through second-order weak interactions. Other, as yet undiscovered particles, which can mediate the decay could provide an enhancement to the branching ratio, which in the Standard Model predicted to be about 2.80E-11. The experiment is expected to observe 100 events at the Standard Model branching ratio for a 10% measurement. The experiment is a follow-up to E391a at KEK and has been approved as experiment E14 at J-PARC. The main barrel vacuum vessel, the charged veto detectors, and the main barrel photon veto system will be reused from E391a. The main calorimeter has been replaced with Cesium Iodide crystals that are both smaller to provide improved shower reconstruction and longer to prevent energy leakage out of the back of the calorimeter. New trigger and data acquisitions electronics will be used.

  10. Precision measurement of muonium hyperfine splitting at J-PARC

    NASA Astrophysics Data System (ADS)

    Kanda, Sohtaro; J-PARC MuHFS Collaboration

    2014-09-01

    Muonium is the bound state of a positive muon and an electron. Because neither muon nor electron has internal structure, muonium's ground state hyperfine splitting (MuHFS) can be the most precise probe for the test of the bound state QED and for the determination of the ratio of magnetic moments of muon and proton. At J-PARC, we plan to perform a precision measurement of the MuHFS via microwave spectroscopy of muonium. Muonium is formed in Kr gas target and state transition between energy levels is induced by microwave resonance. Spectroscopy of the muonium states can be performed by measurement of positron asymmetry from muonium decay. Precision of the most recent experimental result (LAMPF1999) was mostly statistically limited. Hence, improved statistics is essential for higher precision of the measurement. Our goal is to improve accuracy by an order of magnitude compared to the most recent experiment. In order to achieve the goal, we utilize J-PARC's highest-intensity pulsed muon beam (expected intensity is 1 ×108μ+ / s), highly segmented positron detector with SiPM (Silicon PhotoMultiplier), and an online/offline muon beam profile monitor. In this presentation, we discuss the experimental overview and development status of each components.

  11. Quinolone-resistant mutants of escherichia coli DNA topoisomerase IV parC gene.

    PubMed Central

    Kumagai, Y; Kato, J I; Hoshino, K; Akasaka, T; Sato, K; Ikeda, H

    1996-01-01

    Escherichia coli quinolone-resistant strains with mutations of the parC gene, which codes for a subunit of topoisomerase IV, were isolated from a quinolone-resistant gyrA mutant of DNA gyrase. Quinolone-resistant parC mutants were also identified among the quinolone-resistant clinical strains. The parC mutants became susceptible to quinolones by introduction of a parC+ plasmid. Introduction of the multicopy plasmids carrying the quinolone-resistant parC mutant gene resulted in an increase in MICs of quinolones for the parC+ and quinolone-resistant gyrA strain. Nucleotide sequences of the quinolone-resistant parC mutant genes were determined, and missense mutations at position Gly-78, Ser-80, or Glu-84, corresponding to those in the quinolone-resistance-determining region of DNA gyrase, were identified. These results indicate that topoisomerase IV is a target of quinolones in E. coli and suggest that the susceptibility of E. coli cells to quinolones is determined by sensitivity of the targets, DNA gyrase and topoisomerase IV. PMID:8851598

  12. Precision Spectroscopy of Kaonic Helium-3 X-rays at J-PARC

    NASA Astrophysics Data System (ADS)

    Sato, M.; Bhang, H.; Cargnelli, M.; Choi, Seonho; Curceanu, C.; Enomoto, S.; Fujioka, H.; Fujiwara, Y.; Guaraldo, C.; Hashimoto, T.; Hayano, R. S.; Hiraiwa, T.; Iio, M.; Inoue, K.; Ishikawa, T.; Ishimoto, S.; Ishiwatari, T.; Itahashi, K.; Iwasaki, M.; Kou, H.; Kienle, P.; Marton, J.; Matsuda, Y.; Noumi, H.; Ohnishi, H.; Okada, S.; Outa, H.; Romero Vidal, A.; Sakuma, F.; Sekimoto, M.; Shi, H.; Sirghi, D.; Sirghi, F.; Suzuki, T.; Tanida, K.; Tatsuno, H.; Tokuda, M.; Tomono, D.; Toyoda, A.; Tsukada, K.; Vazquez Doce, O.; Widmann, E.; Wünschek, B.; Yamazaki, T.; Zmeskal, J.

    2011-09-01

    We will measure the x-rays from kaonic 3He 3d → 2p transition with a precision below 2 eV. It can provide crucial information on the K--nucleus strong interaction. The experiment (J-PARC E17) will be performed as Day-1, which is one of the first experiments in the J-PARC hadron facility in the year 2011. An overview and the present status of the J-PARC E17 experiment are described.

  13. Precision spectroscopy of kaonic 3He X-rays at J-PARC

    NASA Astrophysics Data System (ADS)

    Sato, M.; Bhang, H.; Cargnelli, M.; Choi, Seonho; Curceanu, C.; Enomoto, S.; Fujioka, H.; Fujiwara, Y.; Guaraldo, C.; Hashimoto, T.; Hayano, R. S.; Hiraiwa, T.; Iio, M.; Inoue, K.; Ishikawa, T.; Ishimoto, S.; Ishiwatari, T.; Itahashi, K.; Iwasaki, M.; Kou, H.; Kienle, P.; Marton, J.; Matsuda, Y.; Noumi, H.; Ohnishi, H.; Okada, S.; Outa, H.; Vidal, A. Romero; Sakuma, F.; Sekimoto, M.; Shi, H.; Sirghi, D.; Sirghi, F.; Suzuki, T.; Tanida, K.; Tatsuno, H.; Tokuda, M.; Tomono, D.; Toyoda, A.; Tsukada, K.; Doce, O. Vazquez; Widmann, E.; Wünschek, B.; Yamazaki, T.; Zmeskal, J.

    2011-10-01

    We will measure the X-rays from kaonic 3He 3d → 2p transition with a precision below 2 eV. It can provide crucial information on the kaon-nucleus strong interaction. The experiment (J-PARC E17) will be performed as Day-1, which is one of the first experiments in the J-PARC hadron facility in the year 2011. An overview and the present status of the J-PARC E17 experiment are described.

  14. Precision spectroscopy of kaonic {sup 3}He X-rays at J-PARC

    SciTech Connect

    Sato, M.; Fujiwara, Y.; Hashimoto, T.; Hayano, R. S.; Ishikawa, T.; Shi, H.; Suzuki, T.; Tatsuno, H.; Bhang, H.; Choi, Seonho; Tanida, K.; Cargnelli, M.; Ishiwatari, T.; Marton, J.; Wuenschek, B.; Zmeskal, J.; Curceanu, C.; Guaraldo, C.; Okada, S.; Vidal, A. Romero

    2011-10-24

    We will measure the X-rays from kaonic {sup 3}He 3d {yields} 2p transition with a precision below 2 eV. It can provide crucial information on the kaon-nucleus strong interaction. The experiment (J-PARC E17) will be performed as Day-1, which is one of the first experiments in the J-PARC hadron facility in the year 2011. An overview and the present status of the J-PARC E17 experiment are described.

  15. Activation of p53-dependent responses in tumor cells treated with a PARC-interacting peptide

    SciTech Connect

    Vitali, Roberta; Cesi, Vincenzo; Tanno, Barbara; Ferrari-Amorotti, Giovanna; Dominici, Carlo; Calabretta, Bruno; Raschella, Giuseppe

    2008-04-04

    We tested the activity of a p53 carboxy-terminal peptide containing the PARC-interacting region in cancer cells with wild type cytoplasmic p53. Peptide delivery was achieved by fusing it to the TAT transduction domain (TAT-p53-C-ter peptide). In a two-hybrid assay, the tetramerization domain (TD) of p53 was necessary and sufficient to bind PARC. The TAT-p53-C-ter peptide disrupted the PARC-p53 complex. Peptide treatment caused p53 nuclear relocation, p53-dependent changes in gene expression and enhancement of etoposide-induced apoptosis. These studies suggest that PARC-interacting peptides are promising candidates for the enhancement of p53-dependent apoptosis in tumors with wt cytoplasmic p53.

  16. Activation of p53-dependent responses in tumor cells treated with a PARC-interacting peptide.

    PubMed

    Vitali, Roberta; Cesi, Vincenzo; Tanno, Barbara; Ferrari-Amorotti, Giovanna; Dominici, Carlo; Calabretta, Bruno; Raschellà, Giuseppe

    2008-04-01

    We tested the activity of a p53 carboxy-terminal peptide containing the PARC-interacting region in cancer cells with wild type cytoplasmic p53. Peptide delivery was achieved by fusing it to the TAT transduction domain (TAT-p53-C-ter peptide). In a two-hybrid assay, the tetramerization domain (TD) of p53 was necessary and sufficient to bind PARC. The TAT-p53-C-ter peptide disrupted the PARC-p53 complex. Peptide treatment caused p53 nuclear relocation, p53-dependent changes in gene expression and enhancement of etoposide-induced apoptosis. These studies suggest that PARC-interacting peptides are promising candidates for the enhancement of p53-dependent apoptosis in tumors with wt cytoplasmic p53. PMID:18230339

  17. Strongest Pulsed Muon Source at J-PARC MUSE

    SciTech Connect

    Miyake, Y.; Shimomura, K.; Kawamura, N.; Strasser, P.; Koda, A.; Fujimori, H.; Makimura, S.; Nakahara, K.; Kato, M.; Takeshita, S.; Nishiyama, K.; Kobayashi, Y.; Kojima, K.; Kadono, R.; Higemoto, W.; Ito, T.; Ninomiya, K.; Hiraishi, M.; Miyazaki, M.; Kubo, K.

    2011-10-06

    The muon science facility (MUSE, abbreviation of MUon Science Establishment), along with the neutron, hadron, and neutrino facilities, is located in the Materials and Life Science Facility (MLF), which is a building integrated to include both neutron and muon science programs. On the November, 2009 beam cycle, we achieved extraction of the world's strongest pulsed muon beam at J-PARC MUSE by beam tuning at the Decay-Surface muon beam line (D-line). Surface muons ({mu}{sup +}) as much as 1.8x10{sup 6}/s were extracted with the use of 120 kW of protons from the Rapid Cycle Synchrotron (RCS), which corresponds to 1.5x10{sup 7}/s surface muons when a future proton beam reached at the intensity of 1MW. These intensities, at the future 1 MW operation, will correspond to more than ten times those at the RIKEN-RAL Muon facility.

  18. Future Heavy-Ion Program at J-PARC

    NASA Astrophysics Data System (ADS)

    Sako, Hiroyuki

    Recently, a heavy ion program as a future J-PARC project has been discussed among nuclear physicists and accelerator scientists. The overview of the heavy-ion program with physics goals, the design and physics feasibility of the spectrometer, and preliminary accelerator schemes are presented. The main goal of the program is to explore the QCD phase diagram in baryon densities 8-10 times as high as the normal nucleus density with heavy ion beams up to uranium at 1-10 AGeV, as well as research of unstable nuclei up to 10 AMeV. In this work, we focus on the former. One of the most important measurements which could signal the phase transition in high baryon densities is a dilepton. We study in-medium modifications of ρ , ω , and φ mesons decaying into dileptons, measure rare particles such as multi-strangeness hadrons, exotic hadrons, and hypernuclei utilizing high rate beams at J-PARC. We have been designing a spectrometer with a solenoid and a dipole magnets, which covers almost 4π acceptance, and has capability of identifying charged hadrons as well as electrons and muons. In one-month running of the experiment at the beam rate of 1011 Hz, we expect to measure ρ , ω , and φ dielectron decays of the order of 107. Heavy-ion acceleration schemes have been studied with a new heavy-ion linac and a new booster ring as an injector to RCS. The beams will be accelerated in RCS and MR. The goal beam rate is around 1010-1011/MR cycle.

  19. Beam position monitor system of J-PARC RCS

    NASA Astrophysics Data System (ADS)

    Hayashi, N.; Kawase, M.; Hatakeyama, S.; Hiroki, S.; Saeki, R.; Takahashi, H.; Teruyama, Y.; Toyokawa, R.; Arakawa, D.; Hiramatsu, S.; Lee, S.; Satou, K.; Tejima, M.; Toyama, T.

    2012-06-01

    The J-PARC RCS is a 25 Hz Rapid-Cycling proton Synchrotron and its designed beam power is 1 MW. The beam position monitor (BPM) system at J-PARC RCS is described in this paper. The pre-defined diameter of the BPM detectors is larger than 250 mm, however, the system has to measure the beam position very accurately. In addition, it is necessary to have a large dynamic range. The system should work not only for the high intensity but also for low intensity, such as during beam commissioning, when the intensity is below 1% of the design intensity. There are 54 BPM detectors around the ring and most of them are placed inside steering magnets because of quite limited space. The BPM detector is an electro-static type and it has four electrodes, and a pair of electrodes gives a good linear response with a diagonal cut shape to detect the charge center precisely. The signal processing units, which are equipped with 14-bit 40 MS/s ADC and 600 MHz DSP, have been developed. They are accessed via shared memory space and controlled by EPICS. Such a processing unit is capable of recording the full 25 Hz pulse data for the so-called "COD mode" (averaged beam position calculation) and it can also store the whole waveform data for further analysis, like turn-by-turn position calculation. The resolution was estimated to be 20 μm for "COD mode" and to be 0.3 mm for the turn-by-turn mode with relatively low intensity of 8×1011 ppp. The position accuracy is estimated to be about 0.5 mm using a newly developed Beam Based Alignment (BBA) method.

  20. A Design for Living: The PARC Plan. Report of the PARC Ad Hoc Planning Committee for Resolution II, October 19, 1974.

    ERIC Educational Resources Information Center

    Pennsylvania Association for Retarded Citizens, Harrisburg.

    Presented is the PARC (Pennsylvania Association for Retarded Citizens) Plan which resulted from a 3-month survey of Pennsylvania's institutional system and which was designed to improve living conditions and programs of state schools and hospitals serving the mentally retarded. Detailed are specific recommendations for the achievement of annual…

  1. Current status of the J-PARC muon facility, MUSE

    NASA Astrophysics Data System (ADS)

    Miyake, Y.; Shimomura, K.; Kawamura, N.; Strasser, P.; Koda, A.; Fujimori, H.; Ikedo, Y.; Makimura, S.; Kobayashi, Y.; Nakamura, J.; Kojima, K.; Adachi, T.; Kadono, R.; Takeshita, S.; Nishiyama, K.; Higemoto, W.; Ito, T.; Nagamine, K.; Ohata, H.; Makida, Y.; Yoshida, M.; Okamura, T.; Okada, R.; Ogitsu, T.

    2014-12-01

    The muon science facility (MUSE), along with the neutron, hadron, and neutrino facilities, is one of the experimental areas of the J-PARC project. The MUSE facility is located in the Materials and Life Science Facility (MLF), which is a building integrated to include both neutron and muon science programs. Since the autumn of 2008, users operation is effective and making use of the pulsed muon beam particularly at the D-Line. Unfortunately, MUSE suffered severe damages from the earthquake on March 11, 2011, the so-called "Higashi-Nippon Dai-Shinsai". We managed to have a stable operation of the superconducting solenoid magnet with use of the on-line refrigerator on December, 2012, although we had to overcome a lot of difficulties against components not working properly. But we had to stop again the whole operations on May 2013, because of the radioactive materials leakage accident at the Hadron Hall Experimental Facility. Finally we restarted the users' runs on February 2014.

  2. Ultra Slow Muon Project at J-PARC, MUSE

    SciTech Connect

    Miyake, Y.; Nakahara, K.; Shimomura, K.; Strasser, P.; Kawamura, N.; Koda, A.; Makimura, S.; Fujimori, H.; Nishiyama, K.; Matsuda, Y.; Bakule, P.; Adachi, T.; Ogitsu, T.

    2009-03-17

    The muon science facility (MUSE), along with the neutron, hadron, and neutrino facilities, is one of the experimental areas of the J-PARC project, which was approved for construction at the Tokai JAEA site. The MUSE facility is located in the Materials and Life Science Facility (MLF), which is a building integrated to include both neutron and muon science programs. Construction of the MLF building was started in the beginning of 2004, and first muon beam is expected in the autumn of 2008.As a next step, we are planning to install, a Super Omega muon channel with a large acceptance of 400 msr, to extract the world strongest pulsed surface muon beam. Its goal is to extract 4x10{sup 8} surface muons/s for the generation of the intense ultra slow muons, utilizing laser resonant ionization of Mu by applying an intense pulsed VUV laser system. As maximum 1x10{sup 6} ultra slow muons/s will be expected, which will allow for the extension of {mu}SR into the field of thin film and surface science.

  3. Operation Status of the J-PARC Ion Source

    NASA Astrophysics Data System (ADS)

    Oguri, Hidetomo; Ohkoshi, Kiyonori; Ikegami, Kiyoshi; Yamazaki, Saishun; Takagi, Akira; Koizumi, Isao; Ueno, Akira

    A cesium-free negative hydrogen ion source driven with a LaB6 filament is being operated for J-PARC. The ion source has been providing a beam for approximately eight years without any serious troubles. The ion source consists of a cylindrical plasma chamber, a beam extractor and a large vacuum chamber with 2 turbo molecular pumps of 1500 l/s for differential pumping. The source plasma is produced by an arc discharge and confined by a multi-cusp magnetic field produced by permanent magnets surrounding the chamber wall. The 50 keV negative hydrogen beam is extracted by applying about -50 kV to the beam extractor. The basic structure of the ion source has not been changed since the operation was started. The ion source has been operated in two different modes such as low current mode of 20 mA and high current mode of 32 mA. Continuous operation for about 1,000 h and about 500 h was achieved in low and high current mode, respectively. After the operation, we replace the filament by a brand-new one to prevent the filament from failing during the operation. The required time for the replacement including the filament degassing process, the vacuuming and the conditioning operation is about 15 h.

  4. PARC/CCL18 Is a Plasma CC Chemokine with Increased Levels in Childhood Acute Lymphoblastic Leukemia

    PubMed Central

    Struyf, Sofie; Schutyser, Evemie; Gouwy, Mieke; Gijsbers, Klara; Proost, Paul; Benoit, Yves; Opdenakker, Ghislain; Van Damme, Jo; Laureys, Geneviève

    2003-01-01

    Chemokines play an important role in leukocyte mobilization, hematopoiesis, and angiogenesis. Tissue-specific expression of particular chemokines also influences tumor growth and metastasis. Here, the CC chemokine pulmonary and activation-regulated chemokine (PARC)/CCL18 was measured in pediatric patients with acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML). Surprisingly, PARC immunoreactivity was consistently detected in plasma from healthy donors. After purification to homogeneity, the presence of intact PARC (1–69) and processed PARC (1–68) in normal human plasma was confirmed by sequence and mass spectrometry analysis. Furthermore, PARC serum levels were significantly increased in children with T-ALL and prepreB-ALL compared to control serum samples, whereas serum levels in AML and preB-ALL patients were not significantly different from controls. In contrast, the hemofiltrate CC chemokine-1 (HCC-1)/CCL14 was not found to be a biomarker in any of these patients’ strata, whereas the cytokine interleukin-6 (IL-6) was significantly decreased in AML and prepreB-ALL. Stimulated leukocytic cell lines or lymphoblasts from patients produced IL-8/CXCL8 or macrophage inflammatory protein-1α (MIP-1α/CCL3) but not PARC, not even after IL-4 or IL-10 treatment. However, PARC was produced by superantigen or IL-4 stimulated monocytes co-cultured with lymphocytes or lymphoblastic cells. Serum PARC levels thus constitute a novel leukemia marker, possibly reflecting tumor/host cell interactions in the circulation. PMID:14578205

  5. PARC Navier-Stokes code upgrade and validation for high speed aeroheating predictions

    NASA Technical Reports Server (NTRS)

    Liver, Peter A.; Praharaj, Sarat C.; Seaford, C. Mark

    1990-01-01

    Applications of the PARC full Navier-Stokes code for hypersonic flowfield and aeroheating predictions around blunt bodies such as the Aeroassist Flight Experiment (AFE) and Aeroassisted Orbital Transfer Vehicle (AOTV) are evaluated. Two-dimensional/axisymmetric and three-dimensional perfect gas versions of the code were upgraded and tested against benchmark wind tunnel cases of hemisphere-cylinder, three-dimensional AFE forebody, and axisymmetric AFE and AOTV aerobrake/wake flowfields. PARC calculations are in good agreement with experimental data and results of similar computer codes. Difficulties encountered in flowfield and heat transfer predictions due to effects of grid density, boundary conditions such as singular stagnation line axis and artificial dissipation terms are presented together with subsequent improvements made to the code. The experience gained with the perfect gas code is being currently utilized in applications of an equilibrium air real gas PARC version developed at REMTECH.

  6. Science Goals of the Primary Atomic Reference Clock in Space (PARCS) Experiment

    NASA Technical Reports Server (NTRS)

    Ashby, N.

    2003-01-01

    The PARCS (Primary Atomic Reference Clock in Space) experiment will use a laser-cooled Cesium atomic clock operating in the microgravity environment aboard the International Space Station (ISS) to provide both advanced tests of gravitational theory and to demonstrate a new cold-atom clock technology for space. PARCS is a joint project of the National Institute of Standards and Technology (NIST), NASA's Jet Propulsion Laboratory (JPL), and the University of Colorado (CU). This paper concentrates on the scientific goals of the PARCS mission. The microgravity space environment allows laser-cooled Cs atoms to have Ramsey times in excess of those feasible on Earth, resulting in improved clock performance. Clock stabilities of 5x10(exp -14) at one second, and accuracies better than 10(exp -16) are projected.

  7. Measurement of neutron capture cross section of Li-7 at J-PARC / MLF / ANNRI

    SciTech Connect

    Makii, H.; Ota, S.; Nishinaka, I.; Nishio, I.; Segawa, M.; Kimura, A.; Harada, H.

    2014-05-02

    We have measured the {sup 7}Li(n,γ){sup 8}Li reaction at Accurate Neutron-Nucleus Reaction Measurement Instrument (ANNRI) installed at the Material and Life science experimental Facility in the Japan Proton Accelerator Research Complex (J-PARC / MLF). In this experiment, we used intense pulsed neutron beam provided by J-PARC / MLF and high performance Ge spectrometer, which is one of the main detectors of the ANNRI. We clearly detected γ rays from the {sup 7}Li(n,γ){sup 8}Li reaction with sufficient signal-to-noise ratio.

  8. Precision Spectroscopy of Kaonic Helium-3 X-rays at J-PARC

    NASA Astrophysics Data System (ADS)

    Hashimoto, T.; Bhang, H.; Cargnelli, M.; Choi, Seonho; Curceanu, C.; Enomoto, S.; Fujioka, H.; Fujiwara, Y.; Guaraldo, C.; Hayano, R. S.; Hiraiwa, T.; Iio, M.; Inoue, K.; Ishikawa, T.; Ishimoto, S.; Ishiwatari, T.; Itahashi, K.; Iwasaki, M.; Kou, H.; Kienle, P.; Marton, J.; Matsuda, Y.; Noumi, H.; Ohnishi, H.; Okada, S.; Outa, H.; Vidal, A. Romero; Sakuma, F.; Sato, M.; Sekimoto, M.; Shi, H.; Sirghi, D.; Sirghi, F.; Suzuki, T.; Tanida, K.; Tatsuno, H.; Tokuda, M.; Tomono, D.; Toyoda, A.; Tsukada, K.; Doce, O. Vazquez; Widmann, E.; Wünschek, B. K.; Yamazaki, T.; Zmeskal, J.

    2011-10-01

    We will measure the x-rays from kaonic 3He and 4He 3d→2p transition by using silicon drift detectors. Our precision goal is set to 1 eV to provide crucial information on the kaon-nucleus strong interaction in the low energy limit. The experiment is to be performed as one of the first experiment in the J-PARC hadron facility (J-PARC E17). An overview and the present status of the experiment are presented.

  9. Precision Spectroscopy of Kaonic Helium-3 X-rays at J-PARC

    SciTech Connect

    Hashimoto, T.; Fujiwara, Y.; Hayano, R. S.; Ishikawa, T.; Sato, M.; Shi, H.; Suzuki, T.; Tatsuno, H.; Bhang, H.; Choi, Seonho; Tanida, K.; Cargnelli, M.; Ishiwatari, T.; Marton, J.; Widmann, E.; Wuenschek, B. K.; Zmeskal, J.; Curceanu, C.; Guaraldo, C.; Okada, S.

    2011-10-21

    We will measure the x-rays from kaonic {sup 3}He and {sup 4}He 3d{yields}2p transition by using silicon drift detectors. Our precision goal is set to 1 eV to provide crucial information on the kaon-nucleus strong interaction in the low energy limit. The experiment is to be performed as one of the first experiment in the J-PARC hadron facility (J-PARC E17). An overview and the present status of the experiment are presented.

  10. Cryogenic system for COMET experiment at J-PARC

    NASA Astrophysics Data System (ADS)

    Ki, Taekyung; Yoshida, Makoto; Yang, Ye; Ogitsu, Toru; Iio, Masami; Makida, Yasuhiro; Okamura, Takahiro; Mihara, Satoshi; Nakamoto, Tatsushi; Sugano, Michinaka; Sasaki, Ken-ichi

    2016-07-01

    Superconducting conductors and cryogenic refrigeration are key factors in the accelerator science because they enable the production of magnets needed to control and detect the particles under study. In Japan, a system for COMET (Coherent Muon to Electron Transition), which will produce muon beam lines, is under the construction at J-PARC (Japan Proton Accelerator Research Complex). The system consists of three superconducting magnets; the first is a pion-capture solenoid, the second is a muon-transport solenoid, and the third is a detector solenoid. It is necessary to cool down the magnets efficiently using two-phase helium and maintain them securely at 4.5 K. For stable cryogenic refrigeration of the magnets, a suitable cooling method, structures, and the irradiation effect on materials should be investigated. In this paper, we focus on the development of an overall cryogenic system for cooling the capture and transport solenoids. A conduction-cooling method is considered for cooling the capture and transport solenoids because of the advantages such as the reduction of total heat load, fewer components, and simplified structure. To supply cryogenic fluids (4.5 K liquid helium and 58 K gas helium) and currents to the conduction-cooled magnets subjected to high irradiation, cryogenic components (cooling paths in the magnets, transfer tubes, and a current lead box) are developed. Based on the environment of high irradiation, the conditions (temperature and pressure) of helium in cooling paths are estimated, as well as the temperature of the capture magnet. We develop a dynamic model for quench simulation and estimate the maximum pressure in the cooling pipe when the capture magnet quenches. We conclude with a discussion of the next steps and estimated challenges for the cryogenic system.

  11. NSF-PARCS: A Case Study in Proxy Climate Syntheses for the CCSP Assessment

    NASA Astrophysics Data System (ADS)

    Duvall, M.; Kaufman, D.; MacDonald, G.

    2004-12-01

    The research agenda of the NSF-funded Paleoenvironmental Arctic Sciences (PARCS) program has focused recently on high-resolution records that provide quantifiable estimates of past climates. Syntheses of this research are planned to meet the needs of both the research community and the US Climate Change Science Program. PARCS provides a case study into how proxy climate data generated by a group of collaborating scientists have input into a broader assessment. PARCS was founded in 1999 as an NSF initiative straddling the Arctic System Science (ARCSS) and the Earth System History (ESH) programs to foster a wide range of research on paleoenvironmental change in the Arctic. In March 2001, the PARCS scientific community met to focus its research agenda with the goal of more directly contributing to global-change assessments by providing high-resolution, quantified estimates of past climate. The result was the science plan, "Modes of Arctic Climate Variability and Warmth," an area of research interest under the ESH Program. The plan identified a suite of deliverables that mesh with products now identified by the 2003 CCSP. PARCS has organized workshops addressing this suite of deliverables on the subjects of warm Arctic scenarios (the last interglacial and the Holocene thermal maximum) and variability in Arctic summer temperatures (annual to decadal scale resolution) to review and assemble proxy climate data in preparation for peer-reviewed summaries and for broader dissemination of data syntheses. The goal is to generate data related to these specific themes, and to integrate these data with records currently being produced by other groups nationally and internationally. The data will be assembled, analyzed, and presented as part of a searchable geo-referenced database. PARCS' vehicle for presenting these syntheses beyond peer-reviewed publication is a web-enabled database. The database is being assembled by a PARCS-dedicated data manager whose duties include creation

  12. TRACE/PARCS Core Modeling of a BWR/5 for Accident Analysis of ATWS Events

    SciTech Connect

    Cuadra A.; Baek J.; Cheng, L.; Aronson, A.; Diamond, D.; Yarsky, P.

    2013-11-10

    The TRACE/PARCS computational package [1, 2] isdesigned to be applicable to the analysis of light water reactor operational transients and accidents where the coupling between the neutron kinetics (PARCS) and the thermal-hydraulics and thermal-mechanics (TRACE) is important. TRACE/PARCS has been assessed for itsapplicability to anticipated transients without scram(ATWS) [3]. The challenge, addressed in this study, is to develop a sufficiently rigorous input model that would be acceptable for use in ATWS analysis. Two types of ATWS events were of interest, a turbine trip and a closure of main steam isolation valves (MSIVs). In the first type, initiated by turbine trip, the concern is that the core will become unstable and large power oscillations will occur. In the second type,initiated by MSIV closure,, the concern is the amount of energy being placed into containment and the resulting emergency depressurization. Two separate TRACE/PARCS models of a BWR/5 were developed to analyze these ATWS events at MELLLA+ (maximum extended load line limit plus)operating conditions. One model [4] was used for analysis of ATWS events leading to instability (ATWS-I);the other [5] for ATWS events leading to emergency depressurization (ATWS-ED). Both models included a large portion of the nuclear steam supply system and controls, and a detailed core model, presented henceforth.

  13. Construction of Superconducting Magnet System for the J-PARC Neutrino Beam Line

    SciTech Connect

    Nakamoto, T.; Wanderer, P.; Sasaki, K.; Ajima, Y.; Araoka, O.; Fujii, Y.; Hastings, N.; Higashi, N.; Iida, M.; Ishii, T.; Kimura, N.; Kobayashi, T.; Makida, Y.; Nakadaira, T.; Ogitsu, T.; Ohhata, H.; Okamura, T.; Sakashita, K.; Sugawara, S.; Suzuki, S.; Tanaka, K.; Tomaru, T.; Terashima, A.; Yamamoto, A.; Ichikawa, A.; Kakuno, H.; Anerella, M.; Escallier, J.; Ganetis, G.; gupta, R.; Jain, A.; Muratore, J.; Parker, B.; Boussuge, T.; Charrier, J.-P.; Arakawa, M.; Ichihara, T.; Minato, T.; Okada, Y.; Itou, A.; Kumaki, T.; Nagami, M.; Takahashi, T.

    2009-10-18

    Following success of a prototype R&D, construction of a superconducting magnet system for J-PARC neutrino beam line has been carried out since 2005. A new conceptual beam line with the superconducting combined function magnets demonstrated the successful beam transport to the neutrino production target.

  14. Calpain-mediated Processing of p53-associated Parkin-like Cytoplasmic Protein (PARC) Affects Chemosensitivity of Human Ovarian Cancer Cells by Promoting p53 Subcellular Trafficking*

    PubMed Central

    Woo, Michael G.; Xue, Kai; Liu, Jiayin; McBride, Heidi; Tsang, Benjamin K.

    2012-01-01

    Resistance to cisplatin (CDDP)-based therapy is a major hurdle to the successful treatment of human ovarian cancer (OVCA), and the chemoresistant phenotype in OVCA cells is associated with Akt-attenuated p53-mediated apoptosis. Pro-apoptotic functions of p53 involve both transcription-dependent and -independent signaling pathways, and dysfunctional localization and/or inactivation of p53 contribute to the development of chemoresistance. PARC is a cytoplasmic protein regulating p53 subcellular localization and subsequent function. Little is known about the molecular mechanisms regulating PARC. Although PARC contains putative caspase-3 cleavage sites, and CDDP is known to induce the activation of caspases and calpains and induce proteasomal degradation of anti-apoptotic proteins, if and how PARC is regulated by CDDP in OVCA are unknown. Here, we present evidence that CDDP promotes calpain-mediated PARC down-regulation, mitochondrial and nuclear p53 accumulation, and apoptosis in chemosensitive but not resistant OVCA cells. Inhibition of Akt is required to sensitize chemoresistant cells to CDDP in a p53-dependent manner, an effect enhanced by PARC down-regulation. CDDP-induced PARC down-regulation is reversible by inhibition of calpain but not of caspases or the 26 S proteasome. Furthermore, in vitro experiments confirm the ability of calpain in mediating Ca2+-dependent PARC down-regulation. The role of Ca2+ in PARC down-regulation was further confirmed as ionomycin-induced PARC down-regulation in both chemosensitive and chemoresistant ovarian cancer cells. The data presented here implicate the regulation of p53 subcellular localization and apoptosis by PARC as a contributing factor in CDDP resistance in OVCA cells and Ca2+/calpain in PARC post-translational processing and chemosensitivity. PMID:22117079

  15. Code Development in Coupled PARCS/RELAP5 for Supercritical Water Reactor

    DOE PAGESBeta

    Hu, Po; Wilson, Paul

    2014-01-01

    The new capability is added to the existing coupled code package PARCS/RELAP5, in order to analyze SCWR design under supercritical pressure with the separated water coolant and moderator channels. This expansion is carried out on both codes. In PARCS, modification is focused on extending the water property tables to supercritical pressure, modifying the variable mapping input file and related code module for processing thermal-hydraulic information from separated coolant/moderator channels, and modifying neutronics feedback module to deal with the separated coolant/moderator channels. In RELAP5, modification is focused on incorporating more accurate water properties near SCWR operation/transient pressure and temperature in themore » code. Confirming tests of the modifications is presented and the major analyzing results from the extended codes package are summarized.« less

  16. Fine-tuning to minimize emittances of J-PARC RF-driven H- ion source

    NASA Astrophysics Data System (ADS)

    Ueno, A.; Ohkoshi, K.; Ikegami, K.; Takagi, A.; Asano, H.; Oguri, H.

    2016-02-01

    The Japan Proton Accelerator Research Complex (J-PARC) cesiated RF-driven H- ion source has been successfully operated for about one year. By the world's brightest level beam, the J-PARC design beam power of 1 MW was successfully demonstrated. In order to minimize the transverse emittances, the rod-filter-field (RFF) was optimized by changing the triple-gap-lengths of each of pairing five piece rod-filter-magnets. The larger emittance degradation seems to be caused by impurity-gases than the RFF. The smaller beam-hole-diameter of the extraction electrode caused the more than expected improvements on not only the emittances but also the peak beam intensity.

  17. Fine-tuning to minimize emittances of J-PARC RF-driven H⁻ ion source.

    PubMed

    Ueno, A; Ohkoshi, K; Ikegami, K; Takagi, A; Asano, H; Oguri, H

    2016-02-01

    The Japan Proton Accelerator Research Complex (J-PARC) cesiated RF-driven H(-) ion source has been successfully operated for about one year. By the world's brightest level beam, the J-PARC design beam power of 1 MW was successfully demonstrated. In order to minimize the transverse emittances, the rod-filter-field (RFF) was optimized by changing the triple-gap-lengths of each of pairing five piece rod-filter-magnets. The larger emittance degradation seems to be caused by impurity-gases than the RFF. The smaller beam-hole-diameter of the extraction electrode caused the more than expected improvements on not only the emittances but also the peak beam intensity. PMID:26932012

  18. Neutron capture cross section measurements at the beam line 04 of J-PARC/MLF

    SciTech Connect

    Igashira, Masayuki; Harada, Hideo; Kiyanagi, Yoshiaki

    2012-11-12

    An Accurate Neutron-Nucleus Reaction measurement Instrument (ANNRI) at the beam line 04 of MLF (Material and Life Sciences Experimental Facilities) of J-PARC (Japan Proton Accelerator Research Complex) was installed to measure neutron capture cross sections related to the research and development of innovative nuclear systems, the study on nuclear astrophysics, etc. ANNRI has two gamma-ray spectrometers: one is a Ge detector array placed at 22 m from the coupled type moderator of the spallation neutron source of J-PARC/MLF and the other is a pair of NaI(Tl) detectors at 28 m. Until the 11th of March, 2011, when we had big earthquakes, we measured capture cross sections of Zr-93, Tc-99, Pd-107, I-129, Cm-244, Cm-246, etc. After checking and repairing ANNRI, we restarted measurements, and ANNRI has been open to worldwide users at present.

  19. Search for 6ΛH hypernucleus by the (π-, K+) reaction at J-PARC

    NASA Astrophysics Data System (ADS)

    Sugimura, Hitoshi; J-Parc E10 Collaboration

    2014-12-01

    We have carried out an experiment to produce the neutron-rich hypernucleus 6ΛH by the (π-,K+) reaction on 6Li target at the pion beam momentum of 1.2 GeV/c (J-PARC E10). In order to calibrate the scale of the missing-mass or of the A binding energy of the hypernucleus, we also measured the 12C(π+,K+)12ΛC, p(π+K+)Σ- and p(π+,K +)E+ reactions. The experiment was performed at the K1.8 beam line of J-PARC Hadron Experimental Facility. The overall collected data sample corresponds to an integrated beam intensity of 1.4 × 1012 pions.

  20. The Application of DAQ-Middleware to the J-PARC E16 Experiment

    NASA Astrophysics Data System (ADS)

    Hamada, E.; Ikeno, M.; Kawama, D.; Morino, Y.; Nakai, W.; Obara, Y.; Ozawa, K.; Sendai, H.; Takahashi, T. N.; Tanaka, M. M.; Yokkaichi, S.

    2015-12-01

    DAQ-Middleware is a software framework for network-distributed data acquisition (DAQ) systems. We adopted the framework for the J-PARC E16 experiment, which requires a DAQ bandwidth of more than 660 MB/spill (two-second spill per six-second cycle). We developed a prototype for the DAQ software and confirmed that the prototype's total throughput satisfies the requirements of the experiment.

  1. Passive active resonant coupler (PARC): A new platform for monolithic integration of photonic devices

    NASA Astrophysics Data System (ADS)

    Saini, Simarjeet

    The explosive growth of telecommunications and data traffic in recent years has hastened the emergence of optical communication networks. As the volume and complexity of network traffic increases, efficient methods are required for routing and distributing the associated optical signals. This in turn has put pressure on optical device technologies. Not only are new and more complex devices required, but they must also be manufactured and packaged in a cost-efficient way. Soon, there will be a shift in the paradigm from using discrete packaged devices in a module to monolithically integrated photonic circuits where multiple functions are achieved in a single chip. This offers a considerable challenge and a great opportunity for device engineers. It is the goal of this work to continue and expand the sphere of knowledge and applicability of Photonic Integrated circuits (PIC's) by proposing and demonstrating a new platform technology for monolithically integrating various active and passive optical devices. The platform, which has been named the ``Passive Active Resonant Coupler (PARC)'', utilizes single epitaxial growth and conventional fabrication schemes. PARC devices rely on coupling between vertical waveguides where each waveguide is optimized for its specific functionality. The coupling is achieved by using a new proposed scheme of resonance over some specially designed tapers. It has been shown experimentally for the first time that very high coupling efficiencies (less than 1 dB loss) can be achieved over very short lengths, typically less than 100 μm. Coupling between different kinds of active and passive waveguides has been experimentally demonstrated. A few basic PIC's such as the 1 × 2 optical switch and the 2 × 2 cross-point switch have been demonstrated by integrating active and passive waveguides using the PARC platform. The demonstrated integration work is in the 1.55 μm wavelength range using InP as a substrate. However, the PARC platform is

  2. A search for deeply-bound kaonic nuclear states at J-PARC

    NASA Astrophysics Data System (ADS)

    Ajimura, S.; Beer, G.; Bhang, H.; Bragadireanu, M.; Buehler, P.; Busso, L.; Cargnelli, M.; Choi, S.; Curceanu, C.; Enomoto, S.; Faso, D.; Fujioka, H.; Fujiwara, Y.; Fukuda, T.; Fukuda, Y.; Guaraldo, C.; Hashimoto, T.; Hayano, R. S.; Hiraiwa, T.; Iio, M.; Iliescu, M.; Inoue, K.; Ishikawa, T.; Ishimoto, S.; Ishiwatari, T.; Itahashi, K.; Iwai, M.; Iwasaki, M.; Kienle, P.; Kou, H.; Marton, J.; Matsuda, Y.; Mizoi, Y.; Morra, O.; Nagae, T.; Noumi, H.; Ohnishi, H.; Okada, S.; Outa, H.; Pietreanu, D.; Sada, Y.; Sakaguchi, A.; Sakuma, F.; Sato, M.; Sekimoto, M.; Sirghi, D.; Sirghi, F.; Suzuki, K.; Suzuki, S.; Suzuki, T.; Tatsuno, H.; Tokuda, M.; Tomono, D.; Toyoda, A.; Tsukada, K.; Widmann, E.; Yamazaki, T.; Yim, H.; Zmeskal, J.

    2010-04-01

    The J-PARC E15 experiment will be performed to search for the simplest kaonic nuclear bound state, K- pp, by the in-flight 3He(K-,n) reaction. The exclusive measurement can be performed by a simultaneous measurement of the missing mass using the primary neutron and the invariant mass via the expected decay, K- pp → Λp → pπ- p. In this report, an overview of the experiment and the preparation status are presented.

  3. A search for deeply bound kaonic nuclear states at J-PARC

    NASA Astrophysics Data System (ADS)

    Hiraiwa, T.; Ajimura, S.; Beer, G.; Bhang, H.; Bragadirenn, M.; Buehler, P.; Busso, L.; Cargnelli, M.; Choi, S.; Curceanu, C.; Enomoto, S.; Faso, D.; Fujioka, H.; Fujiwara, Y.; Fukuda, T.; Fukuda, Y.; Guaraldo, C.; Hashimoto, T.; Hayano, R. S.; Iio, M.; Iliescu, M.; Inoue, K.; Ishikawa, T.; Ishimoto, S.; Ishiwatari, T.; Itahashi, K.; Iwai, M.; Iwasaki, M.; Kienle, P.; Kou, H.; Marton, J.; Matsuda, Y.; Mizoi, Y.; Morra, O.; Nagae, T.; Noumi, H.; Ohnishi, H.; Okada, S.; Outa, H.; Pietreau, D.; Sada, Y.; Sakaguchi, A.; Sakuma, F.; Sato, M.; Sekimoto, M.; Sirghi, D.; Sirghi, F.; Suzuki, K.; Suzuki, S.; Suzuki, T.; Tatsuno, H.; Tokuda, M.; Tomono, D.; Toyoda, A.; Tsukada, K.; Widmann, E.; Yamazaki, T.; Yim, H.; Zmeskal, J.

    2010-08-01

    J-PARC E15 experiment aims to search for the lightest kaonic nuclei, namely K-pp bound states, using in-flight (K-, n) reactions. The advantage of this experiment is to perform exclusive measurement by missing mass study using the primary neutrons and invariant mass spectroscopy via such decay as K-pp→Λp→pπ-p, simultaneously. In this report, an overview of this experiment and the current status are presented.

  4. The Search for Deeply Bound Kaonic Nuclear States at J-Parc

    NASA Astrophysics Data System (ADS)

    Hiraiwa, T.; Ajimura, S.; Beer, G.; Bhang, H.; Bragadireanu, M.; Buehler, P.; Busso, L.; Cargnelli, M.; Choi, S.; Curceanu, C.; Enomoto, S.; Faso, D.; Fujioka, H.; Fujiwara, Y.; Fukuda, T.; Guaraldo, C.; Hashimoto, T.; Hayano, R. S.; Iio, M.; Iliescu, M.; Inoue, K.; Ishikawa, T.; Ishimoto, S.; Ishiwatari, T.; Itahashi, K.; Iwai, M.; Iwasaki, M.; Kienle, P.; Kou, H.; Marton, J.; Matsuda, Y.; Mizoi, Y.; Morra, O.; Nagae, T.; Noumi, H.; Ohnishi, H.; Okada, S.; Outa, H.; Pietreanu, D.; Lener, M. Poli; Vidal, A. Romero; Sada, Y.; Sakaguchi, A.; Sakuma, F.; Sato, M.; Sekimoto, M.; Shi, H.; Sirghi, D.; Sirghi, F.; Suzuki, K.; Suzuki, S.; Suzuki, T.; Tatsuno, H.; Tokuda, M.; Tomono, D.; Toyoda, A.; Tsukada, K.; Doce, O. Vazquez; Widmann, E.; Yamazaki, T.; Yim, H.; Zmeskal, J.

    The J-PARC E15 experiment aims to search for the lightest kaonic nuclear states, namely K-pp, using in-flight (K-, n) reaction on 3He. In this experiment, the missing mass in the (K-, n) reaction and the invariant mass of the decay such as K-pp → Λp → pπ-p will be measured simultaneously. In this article, the experimental feature and the present status are presented.

  5. COMET/PRISM Muon to Electron Conversion at J-PARC

    SciTech Connect

    Hungerford, Ed V.

    2009-12-17

    A new experimental search for coherent, neutrinoless, muon-to-electron conversion from a muonic atom has been proposed for the Japanese Proton Accelerator, J-PARC, now under commissioning. The experiment is completing a conceptual design which proposes a single event sensitivity in the branching ratio of lepton number violating to lepton conserving decays of {approx_equal}0.26x10{sup -16}. This note briefly describes the experiment and its objectives.

  6. Development of GEM trigger electronics for the J-PARC E16 experiment

    NASA Astrophysics Data System (ADS)

    Obara, Y.; Hamada, E.; Ikeno, M.; Kawama, D.; Morino, Y.; Nakai, W.; Ozawa, K.; Sendai, H.; Takahashi, T. N.; Tanaka, M. M.; Uchida, T.; Yokkaichi, S.

    2015-12-01

    At the J-PARC E16 experiment[1], we measure mass spectra of vector mesons in nuclei from the e+e- decay channel with high precision and high statistics. We have developed the trigger system consisting of newly developed ASD ASICs which can extract signals from the GEM foil used as a cathode plane of the induction gap in a GEM chamber and digital electronics using FPGAs which processes binary signals from the ASIC.

  7. A novel precision measurement of muon g - 2 and EDM at J-PARC

    SciTech Connect

    Saito, Naohito; Collaboration: J-PARC g-2 /EDM Collaboration

    2012-07-27

    We propose a new experiment to measure the muon anomalous magnetic moment g - 2 and electric dipole moment with a novel technique called ultra-slow muon beam at J-PARC. Precision measurement of these dipole moments plays an important role in fundamental physics to search for a new physics beynd standard model. The concept of the experiment and its current status is described.

  8. Operation and development status of the J-PARC ion source

    SciTech Connect

    Yamazaki, S. Ikegami, K.; Ohkoshi, K.; Ueno, A.; Koizumi, I.; Takagi, A.; Oguri, H.

    2014-02-15

    A cesium-free H{sup −} ion source driven with a LaB{sub 6} filament is being operated at the Japan Proton Accelerator Research Complex (J-PARC) without any serious trouble since the restoration from the March 2011 earthquake. The H{sup −} ion current from the ion source is routinely restricted approximately 19 mA for the lifetime of the filament. In order to increase the beam power at the linac beam operation (January to February 2013), the beam current from the ion source was increased to 22 mA. At this operation, the lifetime of the filament was estimated by the reduction in the filament current. According to the steep reduction in the filament current, the break of the filament was predicted. Although the filament has broken after approximately 10 h from the steep current reduction, the beam operation was restarted approximately 8 h later by the preparation for the exchange of new filament. At the study time for the 3 GeV rapid cycling synchrotron (April 2013), the ion source was operated at approximately 30 mA for 8 days. As a part of the beam current upgrade plan for the J-PARC, the front end test stand consisting of the ion source and the radio frequency quadrupole is under preparation. The RF-driven H{sup −} ion source developed for the J-PARC 2nd stage requirements will be tested at this test stand.

  9. Operation Status of the J-PARC Negative Hydrogen Ion Source

    SciTech Connect

    Oguri, H.; Ikegami, K.; Ohkoshi, K.; Namekawa, Y.; Ueno, A.

    2011-09-26

    A cesium-free negative hydrogen ion source driven with a lanthanum hexaboride (LaB{sub 6}) filament is being operated without any serious trouble for approximately four years in J-PARC. Although the ion source is capable of producing an H{sup -} ion current of more than 30 mA, the current is routinely restricted to approximately 16 mA at present for the stable operation of the RFQ linac which has serious discharge problem from September 2008. The beam run is performed during 1 month cycle, which consisted of a 4-5 weeks beam operation and a few days down-period interval. At the recent beam run, approximately 700 h continuous operation was achieved. At every runs, the beam interruption time due to the ion source failure is a few hours, which correspond to the ion source availability of more than 99%. The R and D work is being performed in parallel with the operation in order to enhance the further beam current. As a result, the H{sup -} ion current of 61 mA with normalized rms emittance of 0.26 {pi}mm.mrad was obtained by adding a cesium seeding system to a J-PARC test ion source which has the almost same structure with the present J-PARC ion source.

  10. Characterization of a point mutation in the parC gene of Mycoplasma bovirhinis associated with fluoroquinolone resistance.

    PubMed

    Hirose, K; Kawasaki, Y; Kotani, K; Abiko, K; Sato, H

    2004-05-01

    Quinolone-resistant (QR) mutants of Mycoplasma bovirhinis strain PG43 (type strain) were generated by stepwise selection in increasing concentrations of enrofloxacin (ENR). An alteration was found in the quinolone resistance-determining region (QRDR) of the parC gene coding for the ParC subunit of topoisomerase IV from these mutants, but not in the gyrA, gyrB, and parE gene coding for the GyrA and GyrB subunits of DNA gyrase and the ParE subunit of topoisomerase IV. Similarly, such an alteration in QRDR of parC was found in the field isolates of M. bovirhinis, which possessed various levels of QR. The substitution of leucine (Leu) by serine (Ser) at position 80 of QRDR of ParC was observed in both QR-mutants and QR-isolates. This is the first report of QR based on a point mutation of the parC gene in M. bovirhinis. PMID:15228551

  11. Use of the PARC code to estimate the off-design transonic performance of an over/under turboramjet nozzle

    NASA Technical Reports Server (NTRS)

    Lam, David W.

    1995-01-01

    The transonic performance of a dual-throat, single-expansion-ramp nozzle (SERN) was investigated with a PARC computational fluid dynamics (CFD) code, an external flow Navier-Stokes solver. The nozzle configuration was from a conceptual Mach 5 cruise aircraft powered by four air-breathing turboramjets. Initial test cases used the two-dimensional version of PARC in Euler mode to investigate the effect of geometric variation on transonic performance. Additional cases used the two-dimensional version in viscous mode and the three-dimensional version in both Euler and viscous modes. Results of the analysis indicate low nozzle performance and a highly three-dimensional nozzle flow at transonic conditions. In another comparative study using the PARC code, a single-throat SERN configuration for which experimental data were available at transonic conditions was used to validate the results of the over/under turboramjet nozzle.

  12. Genetic evidence for a role of parC mutations in development of high-level fluoroquinolone resistance in Escherichia coli.

    PubMed

    Heisig, P

    1996-04-01

    Fifteen strains of Escherichia coli with MICs of ciprofloxacin (CIP) between 0.015 and 256 micrograms/ml were examined for the presence of mutations in the quinolone resistance-determining region of the gyrA gene and in an analogous region of the parC gene. No mutation was found in a susceptible isolate (MIC of CIP, 0.015 microgram/ml). Four moderately resistant strains (MIC of CIP 0.06 to 4 micrograms/ml) carried one gyrA mutation affecting serine 83, but in only one strain was an additional parC mutation (Gly-78 to Asp) detected. All ten highly resistant strains examined (MIC of CIP, > 4 micrograms/ml) carried two gyrA mutations affecting residues serine 83 and aspartate 87, and at least one parC mutation. These parC mutations included alterations of serine 80 to arginine or isoleucine and glutamate 84 to glycine or lysine. The parC+ and two mutant alleles (parCI-80 and parCI-80,G-84) were inserted into the mobilizable vector pBP507. Transfer of a plasmid-coded parC+ allele into parC+ strains did not alter the susceptibilities towards ciprofloxacin or nalidixic acid, while a significant increase in susceptibility was detectable for parC mutants. This increase, however, did not restore wild-type susceptibility, whereas transfer of a plasmid-coded gyrA+ allele alone or in combination with parC+ did. These data are in agreement with the view that topoisomerase IV is a secondary, less sensitive target for quinolone action in Escherichia coli and that the development of high-level fluoroquinolone resistance in E. coli requires at least one parC mutation in addition to the gyrA mutation(s). PMID:8849244

  13. Rod-filter-field optimization of the J-PARC RF-driven H- ion source

    NASA Astrophysics Data System (ADS)

    Ueno, A.; Ohkoshi, K.; Ikegami, K.; Takagi, A.; Yamazaki, S.; Oguri, H.

    2015-04-01

    In order to satisfy the Japan Proton Accelerator Research Complex (J-PARC) second-stage requirements of an H- ion beam of 60mA within normalized emittances of 1.5πmm•mrad both horizontally and vertically, a flat top beam duty factor of 1.25% (500μs×25Hz) and a life-time of longer than 1month, the J-PARC cesiated RF-driven H- ion source was developed by using an internal-antenna developed at the Spallation Neutron Source (SNS). Although rod-filter-field (RFF) is indispensable and one of the most beam performance dominative parameters for the RF-driven H- ion source with the internal-antenna, the procedure to optimize it is not established. In order to optimize the RFF and establish the procedure, the beam performances of the J-PARC source with various types of rod-filter-magnets (RFMs) were measured. By changing RFM's gap length and gap number inside of the region projecting the antenna inner-diameter along the beam axis, the dependence of the H- ion beam intensity on the net 2MHz-RF power was optimized. Furthermore, the fine-tuning of RFM's cross-section (magnetmotive force) was indispensable for easy operation with the temperature (TPE) of the plasma electrode (PE) lower than 70°C, which minimizes the transverse emittances. The 5% reduction of RFM's cross-section decreased the time-constant to recover the cesium effects after an slightly excessive cesiation on the PE from several 10 minutes to several minutes for TPE around 60°C.

  14. A Search for Deeply Bound Kaonic Nuclear States at J-PARC

    NASA Astrophysics Data System (ADS)

    Ajimura, S.; Beer, G.; Bhang, H.; Bragadireanu, M.; Buehler, P.; Busso, L.; Cargnelli, M.; Choi, S.; Curceanu, C.; Enomoto, S.; Faso, D.; Fujioka, H.; Fujiwara, Y.; Fukuda, T.; Guaraldo, C.; Hashimoto, T.; Hayano, R. S.; Hiraiwa, T.; Iio, M.; Iliescu, M.; Inoue, K.; Ishiguro, Y.; Ishikawa, T.; Ishimoto, S.; Ishiwatari, T.; Itahashi, K.; Iwai, M.; Iwasaki, M.; Kawasaki, S.; Kienle, P.; Kou, H.; Ma, Y.; Marton, J.; Matsuda, Y.; Mizoi, Y.; Morra, O.; Nagae, T.; Noumi, H.; Ohnishi, H.; Okada, S.; Outa, H.; Piscicchia, K.; Lener, M. Poli; Vidal, A. Romero; Sada, Y.; Sakaguchi, A.; Sakuma, F.; Sato, M.; Scordo, A.; Sekimoto, M.; Shi, H.; Sirghi, D.; Sirghi, F.; Suzuki, K.; Suzuki, S.; Suzuki, T.; Tatsuno, H.; Tokuda, M.; Tomono, D.; Toyoda, A.; Tsukada, K.; Doce, O. Vazquez; Widmann, E.; Yamazaki, T.; Yim, H.; Zmeskal, J.

    2013-08-01

    The J-PARC E15 experiment has the aims to search for the simplest kaonic nuclear bound state, K - pp, by the in-flight 3He( K -, n) reaction. The exclusive measurement is performed by a simultaneous measurement of the missing mass using the knocked out neutron and the invariant mass via the expected decay, K - pp → Λ p → pπ- p. In this paper, an overview of the experiment and current data analysis of the engineering runs performed in February and June 2012 are presented.

  15. The K1.8BR spectrometer system at J-PARC

    NASA Astrophysics Data System (ADS)

    Agari, Keizo; Ajimura, Shuhei; Beer, George; Bhang, Hyoungchan; Bragadireanu, Mario; Buehler, Paul; Busso, Luigi; Cargnelli, Michael; Choi, Seonho; Curceanu, Catalina; Enomoto, Shun; Faso, Diego; Fujioka, Hiroyuki; Fujiwara, Yuya; Fukuda, Tomokazu; Guaraldo, Carlo; Hashimoto, Tadashi; Hayano, Ryugo S.; Hiraiwa, Toshihiko; Hirose, Erina; Ieiri, Masaharu; Iio, Masami; Iliescu, Mihai; Inoue, Kentaro; Ishiguro, Yosuke; Ishikawa, Takashi; Ishimoto, Shigeru; Ishiwatari, Tomoichi; Itahashi, Kenta; Iwai, Masaaki; Iwasaki, Masahiko; Kakiguchi, Yutaka; Katoh, Yohji; Kawasaki, Shingo; Kienle, Paul; Kou, Hiroshi; Ma, Yue; Marton, Johann; Matsuda, Yasuyuki; Minakawa, Michifumi; Mizoi, Yutaka; Morra, Ombretta; Muto, Ryotaro; Nagae, Tomofumi; Naruki, Megumi; Noumi, Hiroyuki; Ohnishi, Hiroaki; Okada, Shinji; Outa, Haruhiko; Piscicchia, Kristian; Lener, Marco Poli; Vidal, Antonio Romero; Sada, Yuta; Sakaguchi, Atsushi; Sakuma, Fuminori; Sato, Masaharu; Sato, Yoshinori; Sawada, Shin'ya; Scordo, Alessandro; Sekimoto, Michiko; Shi, Hexi; Shirakabe, Yoshihisa; Sirghi, Diana; Sirghi, Florin; Suzuki, Ken; Suzuki, Shoji; Suzuki, Takatoshi; Suzuki, Yoshihiro; Takahashi, Hitoshi; Tanaka, Kazuhiro; Tanaka, Nobuaki; Tatsuno, Hideyuki; Tokuda, Makoto; Tomono, Dai; Toyoda, Akihisa; Tsukada, Kyo; Doce, Oton Vazquez; Watanabe, Hiroaki; Widmann, Eberhard; Wünschek, Barbara K.; Yamanoi, Yutaka; Yamazaki, Toshimitsu; Yim, Heejoong; Zmeskal, Johann

    2012-11-01

    A new spectrometer system has been designed and constructed at the secondary beam line K1.8BR in the hadron hall of J-PARC to investigate bar {K} N interactions and bar {K}-nuclear bound systems. The spectrometer consists of a high precision beam line spectrometer, a liquid 3He/4He/D2 target system, a cylindrical detector system that surrounds the target to detect the decay particles from the target region, and a neutron time-of-flight counter array located ˜15 m downstream of the target position. Details of the design, construction, and performance of the detector components are described.

  16. Precision Spectroscopy of Kaonic Helium-3 Atoms X-rays at J-PARC

    NASA Astrophysics Data System (ADS)

    Iio, M.; Bhang, H.; Cargnelli, M.; Choi, Seonho; Curceanu, C.; Doce, O. V.; Enomoto, S.; Fujioka, H.; Fujiwara, Y.; Guaraldo, C.; Hashimoto, T.; Hayano, R. S.; Hiraiwa, T.; Ishimoto, S.; Ishiwatari, T.; Itahashi, K.; Iwasaki, M.; Kou, H.; Kienle, P.; Marton, J.; Matsuda, Y.; Noumi, H.; Ohnishi, H.; Okada, S.; Outa, H.; Sakuma, F.; Sato, M.; Sekimoto, M.; Shi, H.; Sirghi, D.; Sirghi, F.; Suzuki, T.; Tanida, K.; Tatsuno, H.; Tokuda, M.; Tomono, D.; Toyoda, A.; Tsukada, K.; Vidal, A. R.; Widmann, E.; Wunschek, B.; Yamazaki, T.; Zmeskal, J.

    2010-04-01

    We will measure the Balmer-series x-rays of kaonic-3He atoms using large-area high-resolution silicon drift x-rays detectors in order to provide the crucial information of K--nucleus strong interaction at the low energy limit. The strong interaction 2p level shift will be determined with a precision of a few eV. At the present status, the construction of all detectors is in progress. In February, 2009, the first tuning of K1.8BR beamline was performed by the secondary beam generated in J-PARC hadron facility. The data taking will be started soon.

  17. Quantum-gravity decoherence effects in neutrino oscillations: Expected constraints from CNGS and J-PARC

    SciTech Connect

    Mavromatos, Nick E.; Sarkar, Sarben; Meregaglia, Anselmo; Sakharov, Alexander S.

    2008-03-01

    Quantum decoherence, the evolution of pure states into mixed states, may be a feature of quantum-gravity models. In most cases, such models lead to fewer neutrinos of all active flavors being detected in a long-baseline experiment as compared to three-flavor standard neutrino oscillations. We discuss the potential of the CNGS and J-PARC beams in constraining models of quantum-gravity induced decoherence using neutrino oscillations as a probe. We use as much as possible model-independent parametrizations, even though they are motivated by specific microscopic models, for fits to the expected experimental data which yield bounds on quantum-gravity decoherence parameters.

  18. Simulation of Phase Modulation for Longitudinal Emittance Blow-Up in J-PARC MR

    NASA Astrophysics Data System (ADS)

    Yamamoto, Masanobu; Ezura, Eizi; Hara, Keigo; Hasegawa, Katsushi; Nomura, Masahiro; Ohmori, Chihiro; Schnase, Alexander; Shimada, Taihei; Takagi, Akira; Takata, Koji; Tamura, Fumihiko; Toda, Makoto; Yoshii, Masahito

    The J-PARC MR provides a coasting proton beam for nuclear physics experiments by slow extraction. The longitudinal emittance should be enlarged until the MR flat top to mitigate the microwave instability. We have investigated a phase modulation method by using a High Frequency Cavity (HFC) to increase the emittance. We have performed extensive simulation studies to find the appropriate parameters of the phase modulation. We found that the effective HFC frequency has a linear dependence with the modulation frequency where the emittance is smoothly enlarged. Furthermore, we confirmed that the required HFC voltage is inverse proportional to the square root of the duration time of the phase modulation.

  19. Production of ultra cold neutrons by a doppler shifter with pulsed neutrons at J-PARC

    NASA Astrophysics Data System (ADS)

    Mishima, K.; Imajo, S.; Hino, M.; Ino, T.; Iwashita, Y.; Katayama, R.; Kitaguchi, M.; Oda, T.; Shimizu, H. M.; Utsuro, M.; Yamashita, S.; Yoshioka, T.

    2014-07-01

    Ultracold neutrons (UCNs) are neutrons whose kinetic energy is around a few hundred nanoelectronvolts. Neutrons with such small kinetic energy can be trapped in a material vessel or magnetic fields. Because of these unique characteristics, UCNs are used for some important experiments of fundamental physics. The Doppler shifter is a device to produce UCN by slowing them down by the reflection on a mirror moving with half of the velocity of incoming neutrons. A Doppler shifter using a quadruple-stack of monochromatic supermirrors that reflects neutrons with a velocity around 68m/s [1, Hino et al.(2010)] was fabricated, and operated with a pulsed neutron source of J-PARC. An important feature of the Doppler shifter is the use of a pulsed neutron beam. Unlike in continuous neutron beams, the neutron velocity can be selected by choosing a time slice in a pulsed neutron bunch. Thus the UCN production improves by ~80 times in the case of J-PARC. We successfully produced the UCNs by the Doppler shifter: the measured UCN production rate is consistent with the simulations.

  20. The Modeling of Advanced BWR Fuel Designs with the NRC Fuel Depletion Codes PARCS/PATHS

    SciTech Connect

    Ward, Andrew; Downar, Thomas J.; Xu, Y.; March-Leuba, Jose A; Thurston, Carl; Hudson, Nathanael H.; Ireland, A.; Wysocki, A.

    2015-04-22

    The PATHS (PARCS Advanced Thermal Hydraulic Solver) code was developed at the University of Michigan in support of U.S. Nuclear Regulatory Commission research to solve the steady-state, two-phase, thermal-hydraulic equations for a boiling water reactor (BWR) and to provide thermal-hydraulic feedback for BWR depletion calculations with the neutronics code PARCS (Purdue Advanced Reactor Core Simulator). The simplified solution methodology, including a three-equation drift flux formulation and an optimized iteration scheme, yields very fast run times in comparison to conventional thermal-hydraulic systems codes used in the industry, while still retaining sufficient accuracy for applications such as BWR depletion calculations. Lastly, the capability to model advanced BWR fuel designs with part-length fuel rods and heterogeneous axial channel flow geometry has been implemented in PATHS, and the code has been validated against previously benchmarked advanced core simulators as well as BWR plant and experimental data. We describe the modifications to the codes and the results of the validation in this paper.

  1. Evaluation of turbulence models in the PARC code for transonic diffuser flows

    NASA Technical Reports Server (NTRS)

    Georgiadis, N. J.; Drummond, J. E.; Leonard, B. P.

    1994-01-01

    Flows through a transonic diffuser were investigated with the PARC code using five turbulence models to determine the effects of turbulence model selection on flow prediction. Three of the turbulence models were algebraic models: Thomas (the standard algebraic turbulence model in PARC), Baldwin-Lomax, and Modified Mixing Length-Thomas (MMLT). The other two models were the low Reynolds number k-epsilon models of Chien and Speziale. Three diffuser flows, referred to as the no-shock, weak-shock, and strong-shock cases, were calculated with each model to conduct the evaluation. Pressure distributions, velocity profiles, locations of shocks, and maximum Mach numbers in the duct were the flow quantities compared. Overall, the Chien k-epsilon model was the most accurate of the five models when considering results obtained for all three cases. However, the MMLT model provided solutions as accurate as the Chien model for the no-shock and the weak-shock cases, at a substantially lower computational cost (measured in CPU time required to obtain converged solutions). The strong shock flow, which included a region of shock-induced flow separation, was only predicted well by the two k-epsilon models.

  2. Measurement of Vector Meson Decays in Nuclei at J-PARC

    NASA Astrophysics Data System (ADS)

    Morino, Y.; Aoki, K.; Aramaki, Y.; En'yo, H.; Hamagaki, H.; Kanaya, J.; Kanno, K.; Kawama, D.; Kiyomichi, A.; Komatsu, Y.; Masumoto, S.; Murakami, H.; Muto, R.; Nakai, W.; Naruki, M.; Obara, Y.; Ozawa, K.; Sakuma, F.; Sawada, S.; Sekimoto, M.; Shibukawa, T.; Shigaki, K.; Takahashi, T. N.; Watanabe, Y. S.; Yokkaichi, S.

    Mass modification of vector meson has been studied in order to investigate the restoration of the chiral symmetry in hot and/or dense matter. Systematical measurement is necessary to confirm the mass modification due to the chiral symmetry restoration. For this purpose, E16 experiment at J-PARC will detect the vector mesons via e + e - decay. A goal of the E16 experiment is to reveal the target mass dependence and the meson velocity dependence of the mass modification through systematic measurement. For that purpose, it is aimed to collect slowly moving φ with typical β γ < 1.25 via di-electron decay as many as possible. The experiment will be performed at the high momentum beam line at J-PARC hadron hall, which supplies a 30-GeV proton beam with an intensity of 2 × 1010 protons per pulse. To cope with the high particle-rate environment, GEMs are used in the E16 spectrometer as the main detectors. To observe a possible second peak due to the modified mass of the φ inside nuclei, 5 MeV/c2 is our goal for the mass resolution. Preparation of the spectrometer construction is now in progress for the first beam time planned at 2016.

  3. The Modeling of Advanced BWR Fuel Designs with the NRC Fuel Depletion Codes PARCS/PATHS

    DOE PAGESBeta

    Ward, Andrew; Downar, Thomas J.; Xu, Y.; March-Leuba, Jose A; Thurston, Carl; Hudson, Nathanael H.; Ireland, A.; Wysocki, A.

    2015-04-22

    The PATHS (PARCS Advanced Thermal Hydraulic Solver) code was developed at the University of Michigan in support of U.S. Nuclear Regulatory Commission research to solve the steady-state, two-phase, thermal-hydraulic equations for a boiling water reactor (BWR) and to provide thermal-hydraulic feedback for BWR depletion calculations with the neutronics code PARCS (Purdue Advanced Reactor Core Simulator). The simplified solution methodology, including a three-equation drift flux formulation and an optimized iteration scheme, yields very fast run times in comparison to conventional thermal-hydraulic systems codes used in the industry, while still retaining sufficient accuracy for applications such as BWR depletion calculations. Lastly, themore » capability to model advanced BWR fuel designs with part-length fuel rods and heterogeneous axial channel flow geometry has been implemented in PATHS, and the code has been validated against previously benchmarked advanced core simulators as well as BWR plant and experimental data. We describe the modifications to the codes and the results of the validation in this paper.« less

  4. Performance evaluation of the Scattered particle Fiber Tracker for J-PARC E10 experiment

    NASA Astrophysics Data System (ADS)

    Nakada, Yoshiyuki; Sakaguchi, Atsushi; Hayakawa, Shuhei H.; Nakagawa, Manami; Oue, Kenichiro; Hayakawa, Tomonari; Miwa, Koji; Honda, Ryotaro; Akazawa, Yuya; Sugimura, Hitoshi; Hasegawa, Shoichi

    2014-09-01

    J-PARC E10 experiment was proposed to produce the neutron-rich Λ-hypernucleus Λ6H by using the 6 Li (π- ,K+) reaction at 1 . 2 GeV / c and to study its structure. The experiment was performed at the K1.8 beam line of J-PARC Hadron Experimental Facility. The Scattered particle Fiber Tracker (SFT) is a scintillating fiber tracker which was newly installed just downstream the target. In this experiment we required high intensity π- beams of typically 1 . 4 ×107 π /spill . So, we replace a tracking wire chamber with SFT to obtain more precise timing information and higher rate tolerance. SFT has x , u , v -planes constructed by scintillating fibers. The light signals from the scintillating fibers are read out by Multi Pixel Photon Counters (MPPCs). The Extended Analogue SiPM ReadOut Chip (EASIROC) system was used as readout electronics. The multi-hit TDC program has introduced in FPGA of the EASIROC system. We analyzed the time information of SFT and studied the influence of high counting rate upon the performance of SFT using the data of the E10 experiment. We report the results of the analysis.

  5. Development of High-Rate Positron Tracker for the Muonium Production Experiment at J-PARC

    NASA Astrophysics Data System (ADS)

    Kanda, S.; Fujimori, H.; Fukao, Y.; Ikedo, Y.; Ishida, K.; Iwasaki, M.; Kawamura, N.; Kojima, K. M.; Lee, M.; Makimura, S.; Mibe, T.; Miyake, Y.; Nakamura, J.; Nagashima, Y.; Nagatomo, T.; Nagumo, K.; Nishimura, S.; Okada, S.; Saito, N.; Shimomura, K.; Suzuki, T.; Strasser, P.; Ueno, K.; Won, E.

    Ultra slow muon is realized by laser ionization of muonium from the production target. The key issue for ultra slow muon is the yield and space-time distribution of muonium. In order to maximize the intensity of ultra slow muon beam, we are developing a muonium production target. There are two major candidates as a target; hot tungsten and silica aerogel. For the target development and its performance evaluation, we need highly rate-capable positron tracker for muonium detection. We have studied basic characteristics of the detector constructed from scintillation fiber and SiPM. As a result of prototype development and its performance evaluation, we finalized the detector design with adequate trackback resolution and high event rate capability for our experiment. The full scale detector was constructed and its laboratory test is ongoing. We have plans of beam experiment with the full scale detector at TRIUMF and J-PARC. The test at TRIUMF will be performed in October 2013 and we submitted an experimental proposal to J-PARC MLF for FY2013.

  6. Development Status of Ion Source at J-PARC Linac Test Stand

    NASA Astrophysics Data System (ADS)

    Yamazaki, S.; Takagi, A.; Ikegami, K.; Ohkoshi, K.; Ueno, A.; Koizumi, I.; Oguri, H.

    The Japan Proton Accelerator Research Complex (J-PARC) linac power upgrade program is now in progress in parallel with user operation. To realize a nominal performance of 1 MW at 3 GeV Rapid Cycling Synchrotron and 0.75 MW at the Main Ring synchrotron, we need to upgrade the peak beam current (50 mA) of the linac. For the upgrade program, we are testing a new front-end system, which comprises a cesiated RF-driven H- ion source and a new radio -frequency quadrupole linac (RFQ). The H- ion source was developed to satisfy the J-PARC upgrade requirements of an H- ion-beam current of 60 mA and a lifetime of more than 50 days. On February 6, 2014, the first 50 mA H- beams were accelerated by the RFQ during a beam test. To demonstrate the performance of the ion source before its installation in the summer of 2014, we tested the long-term stability through continuous beam operation, which included estimating the lifetime of the RF antenna and evaluating the cesium consumption.

  7. Emittance measurements for optimum operation of the J-PARC RF-driven H- ion source

    NASA Astrophysics Data System (ADS)

    Ueno, A.; Ohkoshi, K.; Ikegami, K.; Takagi, A.; Yamazaki, S.; Oguri, H.

    2015-04-01

    In order to satisfy the Japan Proton Accelerator Research Complex (J-PARC) second stage requirements of an H- ion beam of 60mA within normalized emittances of 1.5πmm•mrad both horizontally and vertically, a flat top beam duty factor of 1.25% (500μs×25Hz) and a life-time of longer than 1month, the J-PARC cesiated RF-driven H- ion source was developed by using an internal-antenna developed at the Spallation Neutron Source (SNS). The transverse emittances of the source were measured with various conditions to find out the optimum operation conditions minimizing the horizontal and vertical rms normalized emittances. The transverse emittances were most effectively reduced by operating the source with the plasma electrode temperature lower than 70°C. The optimum value of the cesium (Cs) density around the beam hole of the plasma electrode seems to be proportional to the plasma electrode temperature. The fine control of the Cs density is indispensable, since the emittances seem to increase proportionally to the excessiveness of the Cs density. Furthermore, the source should be operated with the Cs density beyond a threshold value, since the plasma meniscus shape and the ellipse parameters of the transverse emittances seem to be changed step-function-likely on the threshold Cs value.

  8. Progress of the TREK/E36 Experiment at J-PARC

    NASA Astrophysics Data System (ADS)

    Kohl, Michael; TREK/E36 Collaboration

    2015-10-01

    The TREK/E36 experiment is being carried out at J-PARC to provide a precision test of lepton universality in the Ke 2 /Kμ 2 ratio to search for new physics beyond the Standard Model. Simultaneously it will be sensitive to light U(1) gauge bosons and sterile neutrinos below 300 MeV/c2, which could be associated with dark matter or explain established muon-related anomalies such as the muon g - 2 and the proton radius puzzle. The experiment has been set up at the J-PARC K1.1BR kaon beamline since fall 2014, it has been fully commissioned in spring 2015, and is now ready to accumulate production data anticipated in fall 2015. It uses a scintillating fiber target to stop a beam of up to 1.2 Million K+ per spill. The kaon decay products are detected with a large-acceptance toroidal spectrometer capable of tracking charged particles with high resolution, combined with a photon calorimeter with large solid angle and particle identification systems. The status and recent progress of the experiment will be presented. Supported by DOE DE-SC00013941.

  9. ParC subunit of DNA topoisomerase IV of Streptococcus pneumoniae is a primary target of fluoroquinolones and cooperates with DNA gyrase A subunit in forming resistance phenotype.

    PubMed Central

    Muñoz, R; De La Campa, A G

    1996-01-01

    The genes encoding the ParC and ParE subunits of topoisomerase IV of Streptococcus pneumoniae, together with the region encoding amino acids 46 to 172 (residue numbers are as in Escherichia coli) of the pneumococcal GyrA subunit, were partially characterized. The gyrA gene maps to a physical location distant from the gyrB and parC loci on the chromosome, whereas parC is closely linked to parE. Ciprofloxacin-resistant (Cpr) clinical isolates of S. pneumoniae had mutations affecting amino acid residues of the quinolone resistance-determining region of ParC (low-level Cpr) or in both quinolone resistance-determining regions of ParC and GyrA (high-level Cpr). Mutations were found in residue positions equivalent to the serine at position 83 and the aspartic acid at position 87 of the E. coli GyrA subunit. Transformation experiments suggest that ParC is the primary target of ciprofloxacin. Mutation in parC appears to be a prerequisite before mutations in gyrA can influence resistance levels. PMID:8891124

  10. Fatal Levofloxacin Failure in Treatment of a Bacteremic Patient Infected with Streptococcus pneumoniae with a Preexisting parC Mutation▿

    PubMed Central

    de Cueto, M.; Rodríguez, J. M.; Soriano, M. J.; López-Cerero, L.; Venero, J.; Pascual, A.

    2008-01-01

    The fatal outcome of levofloxacin treatment in a patient with bacteremic pneumonia caused by Streptococcus pneumoniae with a preexisting parC mutation is reported. Failure was due to the emergence of a gyrA mutation after 4 days of therapy. Problems encountered in detecting first-step mutation isolates are discussed. PMID:18287316

  11. Interpretation of TRIGA reactivity transients with RELAP5/PARCS coupled-code

    SciTech Connect

    Bandini, G.; Meloni, P.; Polidori, M.

    2006-07-01

    In the frame of future experiments to carried out upon TRIGA reactors, which aim to verify the real feasibility of the ADS (Accelerator Driven System) concept, it is essential to build a numerical tool able to simulate the dynamic behaviour of the reactor in subcritical configuration. This model developed to support the design of subcritical experiments and the safety analysis of the reactor, as a first step has to be assessed against the experimental data available for the critical reactor. To this purpose the thermal-hydraulic/ neutronic numerical model based on the RELAP5/PARCS coupled-code is been tested against the experimental reactivity transients conducted on the RC1-TRIGA reactor at the ENEA Casaccia Research Center in forecast of the TRADE (TRIGA Accelerator Driven Experiment) subcritical experience. The results of the calculations already performed show a qualitative good agreement with the experimental data and allow to address the future developments and improvements of the numerical model. (authors)

  12. Ultra slow muon microscopy by laser resonant ionization at J-PARC, MUSE

    NASA Astrophysics Data System (ADS)

    Miyake, Y.; Ikedo, Y.; Shimomura, K.; Strasser, P.; Kawamura, N.; Nishiyama, K.; Koda, A.; Fujimori, H.; Makimura, S.; Nakamura, J.; Nagatomo, T.; Kadono, R.; Torikai, E.; Iwasaki, M.; Wada, S.; Saito, N.; Okamura, K.; Yokoyama, K.; Ito, T.; Higemoto, W.

    2013-04-01

    As one of the principal muon beam line at the J-PARC muon facility (MUSE), we are now constructing a Muon beam line (U-Line), which consists of a large acceptance solenoid made of mineral insulation cables (MIC), a superconducting curved transport solenoid and superconducting axial focusing magnets. There, we can extract 2 × 108/s surface muons towards a hot tungsten target. At the U-Line, we are now establishing a new type of muon microscopy; a new technique with use of the intense ultra-slow muon source generated by resonant ionization of thermal Muonium (designated as Mu; consisting of a μ + and an e - ) atoms generated from the surface of the tungsten target. In this contribution, the latest status of the Ultra Slow Muon Microscopy project, fully funded, is reported.

  13. Status and Plans of Experiment E17 at J-Parc

    NASA Astrophysics Data System (ADS)

    Wuenschek, B. K.; Bhang, H.; Cargnelli, M.; Choi, S.; Curceanu, C.; Doce, O. Vazquez; Enomoto, S.; Fujioka, H.; Fujiwara, Y.; Guaraldo, C.; Hashimoto, T.; Hayano, R. S.; Hiraiwa, T.; Iio, M.; Ishimoto, S.; Ishiwatari, T.; Itahashi, K.; Iwasaki, M.; Kou, H.; Kienle, P.; Marton, J.; Matsuda, Y.; Noumi, H.; Ohnishi, H.; Okada, S.; Outa, H.; Sakuma, F.; Sato, M.; Sekimoto, M.; Shi, H.; Sirghi, D.; Sirghi, F.; Suzuki, T.; Tanida, K.; Tatsuno, H.; Tokuda, M.; Tomono, D.; Toyoda, A.; Tsukada, K.; Vidal, A. Romero; Widmann, E.; Yamazaki, T.; Zmeskal, J.

    X-ray spectroscopy is an advantageous tool for investigation of the shift and width of the energy levels in kaonic atoms, evoked due to strong interaction between nucleus and kaon. In order to study the 2p level shift in kaonic 3He, the X-ray transition 3p→2d in liquid kaonic 3He will be measured with a precision of <2 eV in the E17 experiment at J-PARC. To reach this desired precision, a well designed setup, in-situ calibration and state-of-the-art semiconductor detectors will be used. The idea and the preparation status of the whole setup will be reported in this article.

  14. Double Hypernuclei Experiment with Hybrid Emulsion Method at J-PARC

    NASA Astrophysics Data System (ADS)

    Ekawa, Hiroyuki

    Double hypernuclei are important probes to study the system with strangeness S = -2. Several emulsion experiments had been performed to search for them. We are planning a new experiment to search for double hypernuclei at the K1.8 beam line in the Hadron Experimental Facility (J-PARC E07 experiment). Ξ- tracks in the emulsion plates and SSD will be automatically connected by a hybrid method. The estimated Ξ- stopped statistics is 10 times as high as that of the KEK E373 experiment. Discoveries of 10 new double hypernuclear species are expected, which enable us to discuss binding energy in terms of mass number dependence. On the other hand, we will also observe X rays from Ξ- atoms with a germanium detector array installed close to theemulsion plates by tagging Ξ- stopped events. This will be the first measurement to give information on the Ξ- potential at the nuclear surface region.

  15. Pressure and temperature fluctuation simulation of J-PARC cryogenic hydrogen system

    NASA Astrophysics Data System (ADS)

    Tatsumoto, H.; Ohtsu, K.; Aso, T.; Kawakami, Y.

    2015-12-01

    The J-PARC cryogenic hydrogen system provides supercritical cryogenic hydrogen to the moderators at a pressure of 1.5 MPa and temperature of 18 K and removes 3.8 kW of nuclear heat from the 1 MW proton beam operation. We prepared a heater for thermal compensation and an accumulator, with a bellows structure for volume control, to mitigate the pressure fluctuation caused by switching the proton beam on and off. In this study, a 1-D simulation code named DiSC-SH2 was developed to understand the propagation of pressure and temperature propagations through the hydrogen loop due to on and off switching of the proton beam. We confirmed that the simulated dynamic behaviors in the hydrogen loop for 300-kW and 500-kW proton beam operations agree well with the experimental data under the same conditions.

  16. Diamond detector for beam profile monitoring in COMET experiment at J-PARC

    NASA Astrophysics Data System (ADS)

    &Cbreve; erv, M.; Sarin, P.; Pernegger, H.; Vageeswaran, P.; Griesmayer, E.

    2015-06-01

    We present the design and initial prototype results of a proton beam profile monitor for the COMET experiment at J-PARC. The goal of COMET is to look for charged lepton flavor violation by direct μ to e conversion at a sensitivity of 10-19. The 8 GeV proton beam pulsed at 100 ns with 1010 protons/s will be used to create muons through pion production and decay. In the final experiment, the proton flux will be raised to 1014 protons/s to increase the sensitivity. These requirements of harsh radiation tolerance and fast readout make diamond a good choice for constructing a beam profile monitor in COMET. We present first results of the characterization of single crystal diamond (scCVD) sourced from a new company 2A SYSTEMS Singapore. Our measurements indicate excellent charge collection and high carrier mobility down to cryogenic temperatures.

  17. Search for muon EDM with ultra-cold muon beam at J-PARC

    NASA Astrophysics Data System (ADS)

    Mibe, Tsutomu; J-PARC muon g-2/EDM Collaboration

    2014-09-01

    The J-PARC experiment E34 aims to measure the anomalous magnetic moment (g-2) and electric dipole moment (EDM) of the positive muon with a novel technique utilizing an ultra-cold muons accelerated to 300 MeV/ c and a 66 cm-diameter compact muon storage ring without focusing-electric field. This measurement will be complementary to the previous BNL E821 experiment and upcoming FNAL E989 experiment with the muon beam at the magic momentum 3.1 GeV/ c in a 14 m-diameter storage ring. The experiment aims to achieve the sensitivity down to 0.1 ppm for g-2, and 10-21 e . cm for EDM. In this presentation, I'd like to discuss the technical achievements and prospects for realization of the experiment.

  18. Muonium production target for the muon g-2/EDM experiment at J-PARC

    NASA Astrophysics Data System (ADS)

    Kanda, Sohtaro

    2014-08-01

    There is more than three standard-deviations discrepancy between measurement and theoretical prediction of the muon anomalous magnetic moment. We are going to measure the precision value of muon g - 2 and search for physics beyond standard model. In addition, we can search for muon EDM which violates CP symmetry. CP violation in charged lepton sector is currently not found. We are developing the 'Ultra Cold Muon Beam' instead of tertiary muon beam with electric focusing. Ultra cold muon is realized by laser ionization of muonium (bound state of a muon and an electron) from the production target. Increase of muonium yield is essential for our experimental goal; 0.1ppm statistical precision. Muonium production experiment at J-PARC MLF MUSE is planned in 2012 autumn. In this paper, we discuss the development of muonium production target and positron detector for the study.

  19. Performance test of a lead-glass counter for the J-PARC E36 experiment

    NASA Astrophysics Data System (ADS)

    Miyazaki, Y.; Shimizu, S.; Bianchin, S.; Djalali, C.; Gill, D.; Jiang, J.; Hasinoff, M.; Horie, K.; Igarashi, Y.; Imazato, J.; Ivashkin, A.; Kohl, M.; Narikawa, R.; Pywell, R.; Strauch, S.; Tabata, M.; Toyoda, A.; Yamazaki, H.; Yoshioka, T.

    2015-04-01

    The J-PARC E36 experiment will search for a violation of lepton universality by a precise measurement of the ratio of the kaon decay widths RK = Γ(K+ →e+ ν) / Γ(K+ →μ+ ν). Charged particles will be identified by the combination of three independent systems: a lead-glass Cherenkov counter, an aerogel Cherenkov counter, and a time-of-flight measurement. The performance of the lead-glass Cherenkov counter was investigated with e+, μ+, and π+ beams in the relevant momentum region from the K+ decays. By using a polyethylene degrader to slow down the beam momentum in front of the lead-glass block, we succeeded in reducing the muon mis-identification probability down to 5% while maintaining a high e+ detection efficiency of 98%.

  20. Current activities and future plans for nuclear data measurements at J-PARC

    NASA Astrophysics Data System (ADS)

    Kimura, Atsushi; Harada, Hideo; Nakamura, Shoji; Iwamoto, Osamu; Toh, Yosuke; Koizumi, Mitsuo; Kitatani, Fumito; Furutaka, Kazuyoshi; Igashira, Masayuki; Katabuchi, Tatsuya; Mizumoto, Motoharu; Hori, Jun-ichi; Kino, Koichi; Kiyanagi, Yoshiaki

    2015-12-01

    In order to improve the data accuracy of neutron-capture cross-sections of minor actinides (MAs) and long-lived fission products (LLFPs), a new experimental instrument named "Accurate Neutron-Nucleus Reaction measurement Instrument" (ANNRI) has been constructed in the Materials and Life science experimental Facility (MLF) at the Japan Proton Accelerator Research Complex (J-PARC), and measurements of neutron-capture cross-sections of MAs, LLFPs and some stable isotopes with high-intensity pulsed neutrons have been started. The analyses for 244Cm, 246Cm, 241Am and 237Np were finished; those for 129I, 107Pd, 99Tc , 93Zr and some stable isotopes are in progress. These results will give significant contributions in the field of developing innovative nuclear systems.

  1. A development of HBD for the J-PARC E16 experiment

    NASA Astrophysics Data System (ADS)

    Aoki, Kazuya; En'yo, Hideto; Gunji, Taku; Hamagaki, Hideki; Kanaya, Junpei; Komatsu, Yusuke; Masumoto, Shinichi; Ozawa, Kyoichiro; Sato, Tsutomu; Sekimoto, Michiko; Tsuji, Tomoya; Utsunomiya, Kazuki; Watanabe, Yosuke; Yokkaichi, Satoshi

    2011-02-01

    Spontaneous breaking of the chiral symmetry is considered to be the origin of hadron mass. The chiral symmetry is expected to be (partially) restored in finite density and the hadron mass is predicted to decrease, even at the normal nuclear density. The J-PARC E16 experiment was proposed to investigate the origin of the mass through the mass modification of vector mesons in a finite density environment. The masses of vector mesons, which are produced in p+A reactions, are measured through the electron-positron decays. A Cherenkov detector with a large acceptance and with fine segmentations is required for the electron identification. HBD is ideal for the purpose; it is a mirror-less, windowless Cherenkov detector with a stack of Gas Electron Multipliers (GEMs) on top of which CsI is evaporated. CF 4 acts as amplification gas and as Cherenkov radiator. We have developed a prototype of HBD for the J-PARC E16 experiment. It is constructed with two layers of Liquid-Crystal-Polymer (LCP) GEMs with a thickness of 100 μm each, on the uppermost surface CsI is evaporated. The use of thicker GEMs leads to a larger gain at the first stage and to tolerance to sparks, compared to regular 50 μm Kapton-GEMs. With a threshold at ˜16 electrons, a pion rejection factor of 100 can be achieved, which is required for the E16 experiment. A beam test was performed with a positron beam and the prototype successfully detected the Cherenkov radiation. The number of photoelectrons observed was about 5-6. Although these results were not satisfactory to reach a pion rejection factor of 100 with a reasonable efficiency at this point, improvements towards the goal are expected from photocathode and gas purity.

  2. Search for New Physics with Experiment E36 at J-PARC

    NASA Astrophysics Data System (ADS)

    Dongwi, Dongwi; TREK/E36 Collaboration

    2016-03-01

    The E36 experiment conducted at J-PARC in Japan will provide a precision test of lepton universality in the Ke 2 /Kμ 2 ratio to search for new physics beyond the Standard Model (SM). The SM prediction for the ratio of leptonic K+ decays is very precise with an uncertainty of △RK /RK = 4 .10-4 . Any observed deviation from the SM prediction would break the universality of the lepton couplings and provide clear indication of New Physics beyond the SM. The detector apparatus allows sensitivity to search for light U (1) gauge bosons and sterile neutrinos below 300 MeV /c2 , which could be associated with dark matter or explain established muon-related anomalies such as the muon g - 2 value, and perhaps the proton radius puzzle. The experiment was set up at the J-PARC K1.1BR kaon beamline in the fall of 2014, fully commissioned in the spring of 2015 and completed production data accumulation in Dec 2015. A scintillating fiber target was used to stop a beam of up to 1.2 Million K+ per spill. The K+ products were detected with a large-acceptance toroidal spectrometer capable of tracking charged particles with high resolution, combined with a CsI(TI) photon detector and particle ID systems. The status of the data analysis will be presented. This work has been supported by DOE awards DE-SC0003884 and DE-SC0013941 in the US, NSERC in Canada, and Kaken-hi in Japan.

  3. Wintertime component of the THORPEX Pacific-Asian Regional Campaign (T-PARC)

    NASA Astrophysics Data System (ADS)

    Song, Y.; Toth, Z.; Asuma, Y.; Reynolds, C.; Lngland, R.; Szunyogh, I.; Colle, B.; Chang, E.; Doyle, C.; Kats, A.

    2009-04-01

    The winter component of the T-PARC is an international field project that aims at improving high impact weather event forecasts for North America. The main objective is to understand how perturbations from the tropics, Eurasia and polar fronts travel through waveguide and turn into high impact weather events. Through adaptive observations by using manned aircrafts (NOAA G-IV and US Air force C-130s) and Russian rawinsonde network over data sparse regions, it is expected that accurate initial conditions will improve the numerical weather forecasts. Non-adaptive aircraft measurements over the Pacific Rim and part of India are also deployed through E-AMDAR program, which is expected to improve the background field over Asia where perturbations are initiated. The campaign is led by NOAA and joined by agencies and universities from US, Canada, Mexico, Japan, ECWMF, and Russia. While most observational data will be assimilated by operational centers to improve real time numerical weather predictions, post field studies will focus on aspects such as: data impact on forecast and analysis, dry and moist processes that affect the formation and propagation of perturbations, meso-scale storm structure, error growth, forecast "busts" under certain atmospheric regimes, and socio-economic applications such as costs and benefits of improved forecasts and their use by the public for high impact weather events. In particular, a Winter Olympics demonstration project (February 12 - February 28) is expected to be a test bed during winter T-PARC for real user outreach and application purposes. Effectiveness of existing targeting methods as well as new targeting methods in the 3-5 day lead time range will be pursued and other aspects related to data assimilation and numerical forecasts (both deterministic and ensemble forecasts) will be investigated within this project as well.

  4. HUMAN RIGHTS ASSESSMENT IN PARC JEAN MARIE VINCENT, PORT-AU-PRINCE, HAITI

    PubMed Central

    Cullen, Kimberly A.; Ivers, Louise C.

    2014-01-01

    Months after a 7.0 magnitude earthquake hit Port-au-Prince, Haiti, over one million remain homeless and living in spontaneous internally displaced person (IDP) camps. Billions of dollars from aid organizations and government agencies have been pledged toward the relief effort, yet many basic human needs, including food, shelter, and sanitation, continue to be unmet. The Sphere Project, “Humanitarian Charter and Minimum Standards in Disaster Response,” identifies the minimum standards to be attained in disaster response. From a human rights perspective and utilizing key indicators from the Sphere Project as benchmarks, this article reports on an assessment of the living conditions approximately 12 weeks after the earthquake in Parc Jean Marie Vincent, a spontaneous IDP camp in Port-au-Prince. A stratified random sample of households in the camp, proportionate to the number of families living in each sector, was selected. Interview questions were designed to serve as “key indicators” for the Sphere Project minimum standards. A total of 486 interviews were completed, representing approximately 5% of households in each of the five sectors of the camp. Our assessment identified the relative achievements and shortcomings in the provision of relief services in Parc Jean Marie Vincent. At the time of this survey, the Sphere Project minimum standards for access to health care and quantity of water per person per day were being met. Food, shelter, sanitation, and security were below minimum accepted standard and of major concern. The formal assessment reported here was completed by September 2010, and is necessarily limited to conditions in Haiti before the cholera outbreak in October. PMID:21178190

  5. Escherichia coli low-copy-number plasmid R1 centromere parC forms a U-shaped complex with its binding protein ParR

    PubMed Central

    Hoischen, C.; Bussiek, M.; Langowski, J.; Diekmann, S.

    2008-01-01

    The Escherichia coli low-copy-number plasmid R1 contains a segregation machinery composed of parC, ParR and parM. The R1 centromere-like site parC contains two separate sets of repeats. By atomic force microscopy (AFM) we show here that ParR molecules bind to each of the 5-fold repeated iterons separately with the intervening sequence unbound by ParR. The two ParR protein complexes on parC do not complex with each other. ParR binds with a stoichiometry of about one ParR dimer per each single iteron. The measured DNA fragment lengths agreed with B-form DNA and each of the two parC 5-fold interon DNA stretches adopts a linear path in its complex with ParR. However, the overall parC/ParR complex with both iteron repeats bound by ParR forms an overall U-shaped structure: the DNA folds back on itself nearly completely, including an angle of ∼150°. Analysing linear DNA fragments, we never observed dimerized ParR complexes on one parC DNA molecule (intramolecular) nor a dimerization between ParR complexes bound to two different parC DNA molecules (intermolecular). This bacterial segrosome is compared to other bacterial segregation complexes. We speculate that partition complexes might have a similar overall structural organization and, at least in part, common functional properties. PMID:18056157

  6. The electronics, online trigger system and data acquisition system of the J-PARC E16 experiment

    NASA Astrophysics Data System (ADS)

    Takahashi, T. N.; Hamada, E.; Ikeno, M.; Kawama, D.; Morino, Y.; Nakai, W.; Obara, Y.; Ozawa, K.; Sendai, H.; Tanaka, M. M.; Uchida, T.; Yokkaichi, S.

    2015-12-01

    The J-PARC E16 experiment was proposed to investigate the restoration of chiral symmetry at the normal nuclear density. E16 will systematically measure in-medium mass of vector mesons at J-PARC Hadron Experimental Facility using a 30-GeV proton beam with an intensity of 2 x 1010 protons per pulse. The E16 spectrometer was designed to detect e+e- from slowly moving vector meson, particularly the ϕ meson. The detector system consists of GEM tracker, Gas Cerenkov detector based on GEM and electromagnetic calorimeter made of lead-glass, whose number of channels reaches about 100,000 in total. The readout electronics, trigger system and data acquisition system for the detectors have been developed, for which level-1 trigger rate of 1-2 kHz is required under several 10 MHz interaction rate. The preparation is underway for the first beam time in 2017.

  7. Development of Single-Sided Silicon Detectors in the Emulsion-Hybrid System at J-PARC

    NASA Astrophysics Data System (ADS)

    Lee, J. Y.; Ahn, J. K.; Ekawa, H.; Han, Y. C.; Hasegawa, S.; Hayakawa, S.; Hayakawa, T.; Hosomi, K.; Hwang, S. H.; Imai, K.; Ito, K.; Kim, M. H.; Kim, S. H.; Kiuchi, R.; Moon, T. J.; Nakazawa, K.; Oue, K.; Sako, H.; Sato, S.; Sugimura, H.; Tanida, K.; Watabe, T.

    A new single-sided silicon micro-strip detector (SSD) is being developed at the J-PARC K1.8 beam line for an emulsion-counter hybrid experiment (J-PARC E07). The SSD will be mainly used for vetex measurements in emulsion plates. Two prototypes of SSD have been fabricated to check the performance of the circuit board and silicon sensors. The first prototype consists of only one layer of a silicon sensor whereas the second prototype consists of two layers of silicon sensors. The final product will be a stack of 4 layers of silicon sensors in the order of X-Y-X-Y. The first and second prototypes of SSD have been tested and the final product will be fabricated based on the test result.

  8. Improvements of Low Level RF Control Systems for J-PARC LINAC 400-MeV Upgrade

    NASA Astrophysics Data System (ADS)

    Fang, Z.; Futatsukawa, K.; Fukui, Y.; Kobayashi, T.; Michizono, S.; Sato, F.; Shinozaki, S.; Chishiro, E.

    The low level RF (LLRF) control systems have been successfully improved for the J-PARC LINAC upgrade. After the installation of 972-MHz high-β acceleration section behind the 324-MHz low-β section beginning in the summer of 2013, the proton beam was successfully accelerated to 400 MeV in January 2014. Many improvements in the LLRF control systems have been carried out to facilitate the operation of the J-PARC LINAC at 400 MeV. The reference 12-MHz signal delay settings for the feedback control systems have been optimized using 12-MHz delay modules. The stability performances of the 972-MHz RF&CLK (Clock) and Mixer&IQ (Mixer & IQ-modulator) boards have been improved using temperature-compensation techniques. By improving the hardware of the feedback control systems, very good stability of the RF systems has been achieved.

  9. Pre-conditioning procedure suitable for internal-RF-antenna of J-PARC RF-driven H- ion source

    NASA Astrophysics Data System (ADS)

    Ueno, A.; Ohkoshi, K.; Ikegami, K.; Takagi, A.; Asano, H.; Oguri, H.

    2016-02-01

    The Japan Proton Accelerator Research Complex (J-PARC) cesiated RF-driven H- ion source has been successfully operated for about 1 yr. By the world brightest level beam, the J-PARC design beam power of 1 MW was successfully demonstrated. Although no internal-RF-antenna failure, except for the once caused by an excess cesium due to a misoperation, occurred in the operation, many antennas failed in pre-conditionings for the first hundred days. The antenna failure rate was drastically decreased by using an antenna with coating thicker than a standard value and the pre-conditioning procedure repeating 15 min 25 kW RF-power operation and impurity-gas evacuation a few times, before the full power (50 kW) operation.

  10. Pre-conditioning procedure suitable for internal-RF-antenna of J-PARC RF-driven H⁻ ion source.

    PubMed

    Ueno, A; Ohkoshi, K; Ikegami, K; Takagi, A; Asano, H; Oguri, H

    2016-02-01

    The Japan Proton Accelerator Research Complex (J-PARC) cesiated RF-driven H(-) ion source has been successfully operated for about 1 yr. By the world brightest level beam, the J-PARC design beam power of 1 MW was successfully demonstrated. Although no internal-RF-antenna failure, except for the once caused by an excess cesium due to a misoperation, occurred in the operation, many antennas failed in pre-conditionings for the first hundred days. The antenna failure rate was drastically decreased by using an antenna with coating thicker than a standard value and the pre-conditioning procedure repeating 15 min 25 kW RF-power operation and impurity-gas evacuation a few times, before the full power (50 kW) operation. PMID:26932011

  11. Search for deeply bound Kaonic nuclear states via 3He(K-, n) reaction at J-PARC

    NASA Astrophysics Data System (ADS)

    Ma, Y.; Ajimura, S.; Beer, G.; Bhang, H.; Bragadireanu, M.; Buehler, P.; Busso, L.; Cargnelli, M.; Choi, S.; Curceanu, C.; Enomoto, S.; Faso, D.; Fujioka, H.; Fujiwara, Y.; Fukuda, T.; Guaraldo, C.; Hashimoto, T.; Hayano, R. S.; Hiraiwa, T.; Iio, M.; Iliescu, M.; Inoue, K.; Ishiguro, Y.; Ishikawa, T.; Ishimoto, S.; Ishiwatari, T.; Itahashi, K.; Iwai, M.; Iwasaki, M.; Kato, Y.; Kawasaki, S.; Kienle, P.; Kou, H.; Marton, J.; Matsuda, Y.; Mizoi, Y.; Morra, O.; Nagae, T.; Noumi, H.; Ohnishi, H.; Okada, S.; Outa, H.; Piscicchia, K.; Lener, M. Poli; Vidal, A. Romero; Sada, Y.; Sakaguchi, A.; Sakuma, F.; Sato, M.; Scordo, A.; Sekimoto, M.; Shi, H.; Sirghi, D.; Sirghi, F.; Suzuki, K.; Suzuki, S.; Suzuki, T.; Tanida, K.; Tatsuno, H.; Tokuda, M.; Tomono, D.; Toyoda, A.; Tsukada, K.; Vazquez Doce, O.; Widmann, E.; Wuenschek, B. K.; Yamaga, T.; Yamazaki, T.; Yim, H.; Zhang, Q.; Zmeskal, J.

    2015-10-01

    As the latest effort to search for deeply-bound overline K-nuclear states, E15 experiment has been carried out at K1.8 branch beam line (K1.8BR) at J-PARC. 3He(K-, N) reaction was employed to search for the simplest overline K-nuclear bound state, K--pp. In this proceeding, preliminary results of 3He(K-, n) spectra obtained in the first physics-run will be presented.

  12. Cytoplasmic CUL9/PARC ubiquitin ligase is a tumor suppressor and promotes p53-dependent apoptosis

    PubMed Central

    Pei, Xin-Hai; Bai, Feng; Li, Zhijun; Smith, Matthew D.; Whitewolf, Gabrielle; Jin, Ran; Xiong, Yue

    2011-01-01

    A wide range of cell stresses, including DNA damage, signal to p53 through post-translational modification of p53. The cytoplasmic functions of p53 are emerging as an important constituent of p53’s role in tumor suppression. Here we report that deletion of the Cul9 (formerly Parc) gene, which encodes an E3 ubiquitin ligase that binds to p53 and localizes in the cytoplasm, resulted in spontaneous tumor development, accelerated Eμ-Myc-induced lymphomagenesis and rendered mice susceptible to carcinogenesis. Cul9-p53 double mutant mice exhibited indistinguishable tumor phenotypes as p53 single mutant mice, indicating that the function of Cul9 in tumor suppression is largely mediated by p53. Deletion of Cul9 had no significant effect on cell cycle progression, but attenuated DNA damage-induced apoptosis. Ectopic expression of wild-type CUL9, but not a point mutant CUL9 deficient in p53 binding, promotes apoptosis. These results demonstrate CUL9 as a potential p53 activating E3 ligase in the cytoplasm. PMID:21487039

  13. SUPERCONDUCTING COMBINED FUNCTION MAGNET SYSTEM FOR J-PARC NEUTRINO EXPERIMENT.

    SciTech Connect

    OGITSU, T.; AJIMA, Y.; ANERELLA, M.; ESCALLIER, J.; GANETIS, G.; GUPTA, R.; HAGEDOM, D.; HARRISON, M.; HIGASHI, N.; IWAMOTO, Y.; ICHIKAWA, A.; JAIN, A.; KIMURA, N.; KOBAYASHI, T.; MAKIDA, Y.; MURATORE, J.; NAKAMOTO, T.; OHHATA, H.; TAKASAKI, N.; TANAKA, K.; TERASHIMA, A.; YAMOMOTO, A.; OBANA, T.; PARKER, B.; WANDERER, P.

    2004-10-03

    The J-PARC Neutrino Experiment, the construction of which starts in JFY 2004, will use a superconducting magnet system for its primary proton beam line. The system, which bends the 50 GeV 0.75 MW proton beam by about 80 degrees, consists of 28 superconducting combined function magnets. The magnets utilize single layer left/right asymmetric coils that generate a dipole field of 2.6 T and a quadrupole field of 18.6 T/m with the operation current of about 7.35 kA. The system also contains a few conduction cooled superconducting corrector magnets that serve as vertical and horizontal steering magnets. All the magnets are designed to provide a physical beam aperture of 130 mm in order to achieve a large beam acceptance. Extensive care is also required to achieve safe operation with the high power proton beam. The paper summarizes the system design as well as some safety analysis results.

  14. Development of GEM Tracker for the J-PARC E16 experiment

    NASA Astrophysics Data System (ADS)

    Obara, Yuki; J-PARC E16 Collaboration

    2014-09-01

    A GEM Tracker (GTR) is a micro-pattern gas detector using GEM foils for tracking charged particles. In the J-PARC E16 experiment, momenta of electrons and positrons from decays of the ϕ meson are measured by three layers of the GTRs whose sizes are 100 × 100 , 200 × 200 , and 300 × 300mm2 in a magnetic field. In order to achieve a mass resolution of 5MeV /c2 , position resolutions of 100 μm in a bending direction by the magnetic field and 700 μm in a direction perpendicular to the bending plane are required. Note that an incident angle of charged tracks to the GTR in the bending plane is up to 30°. To cope with the inclined tracks, a new analysis method called ``timing method'' was developed. We have developed GTRs satisfying the requirements and evaluated their performance, such as a position resolution and detection efficiency, by beam tests. Incident angle dependencies of the evaluated items for all sizes of the GTRs were obtained as the test results. We are ready to start a final detector production for the GTRs. In this presentation, we report our GTRs and the achieved performance.

  15. Double antikaonic nuclear clusters in antiproton-3He annihilation at J-PARC

    NASA Astrophysics Data System (ADS)

    Sakuma, Fuminori; Curceanu, Catalina; Iwasaki, Masahiko; Kienle, Paul; Ohnishi, Hiroaki; Tokuda, Makoto; Tsukada, Kyo; Widmann, Eberhard; Yamazaki, Toshimitsu; Zmeskal, Johannes

    We search for double anti-kaon nuclear bound states in the bar p annihilation reaction in 3He nuclei at rest. In view of the strongly attractive bar K N interaction, the existence of nuclear clusters with more than one K - has been predicted theoretically. The double anti-kaon production in elementary antiproton annihilation at rest is forbidden because of the negative Q-value; however, a double anti-kaon nuclear bound state, such as K - K - pp, with deep binding energy would enable double anti-kaon production in the nuclei. In order to investigate the K - K - pp production in the bar p + ^3He to K^+ + K^0 + X (X = K^-K^-pp) channel, the produced K - K - pp cluster is identified both using missing mass spectroscopy via the K + K 0 channel with a Λ-tag, and invariant mass analysis of the expected decay particles from the K - K - pp cluster such as ΛΛ. We propose to perform the experiment at the existing K1.8BR beam line at J-PARC with the E15 spectrometer.

  16. Double antikaonic nuclear clusters in antiproton-3He annihilation at J-PARC

    NASA Astrophysics Data System (ADS)

    Sakuma, Fuminori; Curceanu, Catalina; Iwasaki, Masahiko; Kienle, Paul; Ohnishi, Hiroaki; Tokuda, Makoto; Tsukada, Kyo; Widmann, Eberhard; Yamazaki, Toshimitsu; Zmeskal, Johannes

    2012-12-01

    We search for double anti-kaon nuclear bound states in the bar p annihilation reaction in 3He nuclei at rest. In view of the strongly attractive bar K N interaction, the existence of nuclear clusters with more than one K - has been predicted theoretically. The double anti-kaon production in elementary antiproton annihilation at rest is forbidden because of the negative Q-value; however, a double anti-kaon nuclear bound state, such as K - K - pp, with deep binding energy would enable double anti-kaon production in the nuclei. In order to investigate the K - K - pp production in the bar p + ^3He to K^+ + K^0 + X (X = K^-K^-pp) channel, the produced K - K - pp cluster is identified both using missing mass spectroscopy via the K + K 0 channel with a Λ-tag, and invariant mass analysis of the expected decay particles from the K - K - pp cluster such as ΛΛ. We propose to perform the experiment at the existing K1.8BR beam line at J-PARC with the E15 spectrometer.

  17. Computation of Supersonic Jet Mixing Noise Using PARC Code With a kappa-epsilon Turbulence Model

    NASA Technical Reports Server (NTRS)

    Khavaran, A.; Kim, C. M.

    1999-01-01

    A number of modifications have been proposed in order to improve the jet noise prediction capabilities of the MGB code. This code which was developed at General Electric, employees the concept of acoustic analogy for the prediction of turbulent mixing noise. The source convection and also refraction of sound due to the shrouding effect of the mean flow are accounted for by incorporating the high frequency solution to Lilley's equation for cylindrical jets (Balsa and Mani). The broadband shock-associated noise is estimated using Harper-Bourne and Fisher's shock noise theory. The proposed modifications are aimed at improving the aerodynamic predictions (source/spectrum computations) and allowing for the non- axisymmetric effects in the jet plume and nozzle geometry (sound/flow interaction). In addition, recent advances in shock noise prediction as proposed by Tam can be employed to predict the shock-associated noise as an addition to the jet mixing noise when the flow is not perfectly expanded. Here we concentrate on the aerodynamic predictions using the PARC code with a k-E turbulence model and the ensuing turbulent mixing noise. The geometry under consideration is an axisymmetric convergent-divergent nozzle at its design operating conditions. Aerodynamic and acoustic computations are compared with data as well as predictions due to the original MGB model using Reichardt's aerodynamic theory.

  18. Study for s-process using neutron beam provided from ANNRI of J-PARC

    NASA Astrophysics Data System (ADS)

    Hayakawa, Takehioto; Toh, Yosuke; Kimura, Akira; Nakamura, Shoji; Shizuma, Toshiyuki; Harada, Hideo

    2016-06-01

    Most isotopes heavier than iron are synthesized by the slow neutron capture reaction process (s-process) in stars. Isomers in stable isotopes have sometimes an important role as a branching point in nucleosynthesis flow in the s-process. An isomer with a half-life of 14.1 y in 113Cd is a branching point from which a nucleosynthesis flow reaches to a rare isotope 115Sn. The astrophysical origin of 115Sn has remained still an open question. The s-process abundance of 115Sn depends on the ratio of the 112Cd(n, γ) 113Cdm reaction cross section to the 112Cd(n, γ) 113Cdgs reaction cross section. However, the isomer production ratio following the neutron capture reaction has not been measured in the energy region higher than the thermal energy. An intense neutron beam experimental system, ANNRI, in J-PARC has a high purity germanium (HPGe) detector system consisting of two cluster detectors. We have measured γ-rays decaying to the ground state and the isomer using the HPGe detectors in conjunction with a time-offlight method at ANNRI.

  19. Operational characteristics of the J-PARC cryogenic hydrogen system for a spallation neutron source

    SciTech Connect

    Tatsumoto, Hideki; Ohtsu, Kiichi; Aso, Tomokazu; Kawakami, Yoshihiko; Teshigawara, Makoto

    2014-01-29

    The J-PARC cryogenic hydrogen system provides supercritical hydrogen with the para-hydrogen concentration of more than 99 % and the temperature of less than 20 K to three moderators so as to provide cold pulsed neutron beams of a higher neutronic performance. Furthermore, the temperature fluctuation of the feed hydrogen stream is required to be within ± 0.25 K. A stable 300-kW proton beam operation has been carried out since November 2012. The para-hydrogen concentrations were measured during the cool-down process. It is confirmed that para-hydrogen always exists in the equilibrium concentration because of the installation of an ortho-para hydrogen convertor. Propagation characteristics of temperature fluctuation were measured by temporarily changing the heater power under off-beam condition to clarify the effects of a heater control for thermal compensation on the feed temperature fluctuation. The experimental data gave an allowable temperature fluctuation of ± 1.05 K. It is clarified through a 286-kW and a 524-kW proton beam operations that the heater control would be applicable for the 1-MW proton beam operation by extrapolating from the experimental data.

  20. Status of the TREK/E36 Experiment at J-PARC

    NASA Astrophysics Data System (ADS)

    Kohl, Michael; TREK/E36 Collaboration

    2015-04-01

    The TREK/E36 experiment will provide a precision test of lepton universality in the Ke 2 /Kμ 2 ratio to search for new physics beyond the Standard Model. Simultaneously it will search for light U(1) gauge bosons and sterile neutrinos below 300 MeV/c2, which could be associated with dark matter or explain established muon-related anomalies such as the muon anomalous magnetic moment and the proton radius puzzle. The experiment is scheduled to run in 2015 at the J-PARC K1.1BR kaon beamline. It uses a scintillating fiber target to stop a beam of up to 106 positive kaons per second. The kaon decay products are detected with a large-acceptance toroidal spectrometer capable of tracking charged particles with high resolution, combined with a photon calorimeter with large solid angle and redundant particle identification systems. An overview of the planned experiment and the current project status will be presented. This project has been supported by DOE Early Career Award DE-SC0003884.

  1. Review of (n,gamma) reactions in astrophysics and scope at J-PARC

    NASA Astrophysics Data System (ADS)

    Nagai, Yasuki

    2009-10-01

    A neutron capture reaction cross section of a nucleus at stellar temperatureis one of important key parameters in the construction of stellar models. A measurement of the mentioned cross section has been carried out worldwide using various neutron sources and various detectors to detect γ-rays promptly emitted from a neutron capture reaction of a nucleus at stellar energy. I will review recent works of the neutron capture reactions of stable and/or unstable nuclei from nuclear astrophysics interest, including our recent work of the neutron capture reaction cross section measurement of ^208Pb. I also discuss a new facility for a neutron capture reaction study at J-PARC. A new beam line (BL04) was constructed in the in the Materials and Life Science Facility (MLF). Two sample positions are located at 20 amd 25 m away from the spallation neutron source, where anti-Compton Ge and NaI(Tl) spectrometers are placed, respectively. An experiment to measure the cross section of minor actinide isotopes has started since last November at a proton beam power of 20 kW.

  2. Fluoroquinolone Resistance Mutations in the parC, parE, and gyrA Genes of Clinical Isolates of Viridans Group Streptococci

    PubMed Central

    González, Irene; Georgiou, Marios; Alcaide, Fernando; Balas, Delia; Liñares, Josefina; de la Campa, Adela G.

    1998-01-01

    The nucleotide sequences of the quinolone resistance-determining regions (QRDRs) of the parC and gyrA genes from seven ciprofloxacin-resistant (Cpr) isolates of viridans group streptococci (two high-level Cpr Streptococcus oralis and five low-level Cpr Streptococcus mitis isolates) were determined and compared with those obtained from susceptible isolates. The nucleotide sequences of the QRDRs of the parE and gyrB genes from the five low-level Cpr S. mitis isolates and from the NCTC 12261 type strain were also analyzed. Four of these low-level Cpr isolates had changes affecting the subunits of DNA topoisomerase IV: three in Ser-79 (to Phe or Ile) of ParC and one in ParE at a position not previously described to be involved in quinolone resistance (Pro-424). One isolate did not show any mutation. The two high-level Cpr S. oralis isolates showed mutations affecting equivalent residue positions of ParC and GyrA, namely, Ser-79 to Phe and Ser-81 to Phe or Tyr, respectively. The parC mutations were able to transform Streptococcus pneumoniae to ciprofloxacin resistance, while the gyrA mutations transformed S. pneumoniae only when mutations in parC were present. These results suggest that DNA topoisomerase IV is a primary target of ciprofloxacin in viridans group streptococci, DNA gyrase being a secondary target. PMID:9797205

  3. Analysis of the OECD/NRC BWR Turbine Trip Transient Benchmark with the Coupled Thermal-Hydraulics and Neutronics Code TRAC-M/PARCS

    SciTech Connect

    Lee, Deokjung; Downar, Thomas J.; Ulses, Anthony; Akdeniz, Bedirhan; Ivanov, Kostadin N.

    2004-10-15

    An analysis of the Peach Bottom Unit 2 Turbine Trip 2 (TT2) experiment has been performed using the U.S. Nuclear Regulatory Commission coupled thermal-hydraulics and neutronics code TRAC-M/PARCS. The objective of the analysis was to assess the performance of TRAC-M/PARCS on a BWR transient with significance in two-phase flow and spatial variations of the neutron flux. TRAC-M/PARCS results are found to be in good agreement with measured plant data for both steady-state and transient phases of the benchmark. Additional analyses of four fictitious extreme scenarios are performed to provide a basis for code-to-code comparisons and comprehensive testing of the thermal-hydraulics/neutronics coupling. The obtained results of sensitivity studies on the effect of direct moderator heating on transient simulation indicate the importance of this modeling aspect.

  4. PARC - Scientific Exchange Program (A "Life at the Frontiers of Energy Research" contest entry from the 2011 Energy Frontier Research Centers (EFRCs) Summit and Forum)

    SciTech Connect

    Blankenship, Robert E.; PARC Staff

    2011-05-01

    'PARC - Scientific Exchange Program' was submitted by the Photosynthetic Antenna Research Center (PARC) to the 'Life at the Frontiers of Energy Research' video contest at the 2011 Science for Our Nation's Energy Future: Energy Frontier Research Centers (EFRCs) Summit and Forum. Twenty-six EFRCs created short videos to highlight their mission and their work. PARC, an EFRC directed by Robert E. Blankenship at Washington University in St. Louis, is a partnership of scientists from ten institutions. The Office of Basic Energy Sciences in the U.S. Department of Energy's Office of Science established the 46 Energy Frontier Research Centers (EFRCs) in 2009. These collaboratively-organized centers conduct fundamental research focused on 'grand challenges' and use-inspired 'basic research needs' recently identified in major strategic planning efforts by the scientific community. The overall purpose is to accelerate scientific progress toward meeting the nation's critical energy challenges.

  5. PARC - Scientific Exchange Program (A "Life at the Frontiers of Energy Research" contest entry from the 2011 Energy Frontier Research Centers (EFRCs) Summit and Forum)

    ScienceCinema

    Blankenship, Robert E. (Director, Photosynthetic Antenna Research Center); PARC Staff

    2011-11-03

    'PARC - Scientific Exchange Program' was submitted by the Photosynthetic Antenna Research Center (PARC) to the 'Life at the Frontiers of Energy Research' video contest at the 2011 Science for Our Nation's Energy Future: Energy Frontier Research Centers (EFRCs) Summit and Forum. Twenty-six EFRCs created short videos to highlight their mission and their work. PARC, an EFRC directed by Robert E. Blankenship at Washington University in St. Louis, is a partnership of scientists from ten institutions. The Office of Basic Energy Sciences in the U.S. Department of Energy's Office of Science established the 46 Energy Frontier Research Centers (EFRCs) in 2009. These collaboratively-organized centers conduct fundamental research focused on 'grand challenges' and use-inspired 'basic research needs' recently identified in major strategic planning efforts by the scientific community. The overall purpose is to accelerate scientific progress toward meeting the nation's critical energy challenges.

  6. Maintenance and operation procedure, and feedback controls of the J-PARC RF-driven H- ion source

    NASA Astrophysics Data System (ADS)

    Ueno, A.; Ohkoshi, K.; Ikegami, K.; Takagi, A.; Yamazaki, S.; Oguri, H.

    2015-04-01

    In order to satisfy the Japan Proton Accelerator Research Complex (J-PARC) second stage requirements of an H- ion beam of 60mA within normalized emittances of 1.5πmm•mrad both horizontally and vertically, a flat top beam duty factor of 1.25% (500μs×25Hz) and a life-time of longer than 1month, the J-PARC cesiated RF-driven H- ion source was developed by using an internal-antenna developed at the Spallation Neutron Source (SNS). The maintenance and operation procedure to minimize the plasma chamber (PCH) replacement time on the beam line, which is very important to maximize the J-PARC beam time especially for an antenna failure, is presented in this paper. The PCH preserved by filling argon (Ar) gas inside after pre-conditioning including pre-cesiation to produce the required beam at a test-stand successfully produced the required beam on the beam line with slight addition of cesium (Cs). The methods of the feedback controls of a 2MHz-RF-matching, an H- ion beam intensity and the addition of Cs are also presented. The RF-matching feedback by using two vacuum variable capacitors (VVCs) and RF-frequency shift produced the almost perfect matching with negligibly small reflected RF-power. The H- ion beam intensity was controlled within errors of ±0.1mA by the RF-power feedback. The amount of Cs was also controlled by remotely opening a Cs-valve to keep the RF-power lower than a settled value.

  7. Rod-filter-field optimization of the J-PARC RF-driven H{sup −} ion source

    SciTech Connect

    Ueno, A. Ohkoshi, K.; Ikegami, K.; Takagi, A.; Yamazaki, S.; Oguri, H.

    2015-04-08

    In order to satisfy the Japan Proton Accelerator Research Complex (J-PARC) second-stage requirements of an H{sup −} ion beam of 60mA within normalized emittances of 1.5πmm•mrad both horizontally and vertically, a flat top beam duty factor of 1.25% (500μs×25Hz) and a life-time of longer than 1month, the J-PARC cesiated RF-driven H{sup −} ion source was developed by using an internal-antenna developed at the Spallation Neutron Source (SNS). Although rod-filter-field (RFF) is indispensable and one of the most beam performance dominative parameters for the RF-driven H{sup −} ion source with the internal-antenna, the procedure to optimize it is not established. In order to optimize the RFF and establish the procedure, the beam performances of the J-PARC source with various types of rod-filter-magnets (RFMs) were measured. By changing RFM’s gap length and gap number inside of the region projecting the antenna inner-diameter along the beam axis, the dependence of the H{sup −} ion beam intensity on the net 2MHz-RF power was optimized. Furthermore, the fine-tuning of RFM’s cross-section (magnetmotive force) was indispensable for easy operation with the temperature (T{sub PE}) of the plasma electrode (PE) lower than 70°C, which minimizes the transverse emittances. The 5% reduction of RFM’s cross-section decreased the time-constant to recover the cesium effects after an slightly excessive cesiation on the PE from several 10 minutes to several minutes for T{sub PE} around 60°C.

  8. Closeout Report - Search for Time Reversal Symmetry Violation with TREK at J-PARC

    SciTech Connect

    Kohl, Michael

    2015-04-15

    This DOE Early Career Award has enabled Dr. Michael Kohl to take on and expand his leadership roles in several projects such as TREK@J-PARC, OLYMPUS@DESY, MUSE@PSI, and in the experimental program in Hall C at Jefferson Lab. Dr. Kohl has successfully accomplished several items: (i) Preliminary results from SANE (E08-003) at Jefferson Lab: Former HU graduate student Anusha Liyanage has pursued her PhD research on SANE. Her analysis of the elastic ep scattering data has resulted in the extraction of the proton electric-to-magnetic form factor ratio from double spin asymmetries at the highest momentum transfer to date. The results are almost final and a publication is in preparation. (ii) Approval of TREK/E36 for running, preparation of simulation and analysis: the TREK experiment has been stage-II approved in fall 2013, has been mounted on the hall floor from November 2014 to April 2015, has been commissioned in April-June 2015 and is scheduled to run in fall 2015. The group has contributed significantly with simulations and magnetic field map calculations, has investigated the sensitivity of TREK to new light neutral particles, and contributed substantially to the mounting and commissioning of the experiment. (iii) Running of OLYMPUS and analysis: Under Dr. Kohl's leadership as spokesman, the OLYMPUS experiment has completed data taking beginning of 2013; calibrations and analysis have been well underway, with results to be expected in the course of 2015. (iv) Operation of GEM detectors at OLYMPUS and MUSE: The GEM telescopes built for OLYMPUS luminosity monitoring with forward-angle ep elastic scattering have been operated successfully, have meanwhile been relocated to PSI, and have been re-commissioned as beam particle trackers for the PSI secondary beams for MUSE. (v) Trained and prepared postdocs and graduate students for their future careers. Two postdocs from Dr. Kohl's group (Dr. Juergen Diefenbach and Dr. Peter Monaghan) have found permanent academic

  9. Operation of the SKS Magnet at the K1.8 Beam Line in the J-PARC Hadron Hall

    NASA Astrophysics Data System (ADS)

    Aoki, K.; Takahashi, T.; Makida, Y.; Okamura, T.; Suzuki, S.; Araoka, O.; Iida, M.; Ohhata, H.; Kawai, M.; Iwasaki, R.; Kondo, Y.; Kasami, K.; Kakiguchi, Y.; Shirakabe, Y.; Sekimoto, M.

    The Superconducting Kaon Spectrometer (SKS) magnet has been operated for 5 years in the hadron hall of the Japan Proton Accelerator Research Complex (J-PARC). The SKS had two long-term suspensions. One was due to damage by the 2011 off Pacific coast Tohoku Earthquake and the other was caused by the radioactive material leak accident at the hadron hall that occurred on May 23, 2013. The SKS was planned to be moved to another beam line to repair the damage caused by the earthquake. The planned move was postponed for processing after the accident.

  10. A Search for deeply-bound Kaonic nuclear state at the J-PARC E15 experiment

    SciTech Connect

    Sada, Y.

    2011-10-21

    The J-PARC E15 experiment will be performed to search for the simplest kaonic nuclear bound state, K-barNN, by the in-flight {sup 3}He(K{sup -},N) reaction. The exclusive measurement can be performed by a simultaneous measurement of the missing mass using the primary neutron or proton, and the invariant mass via the expected decay, e.g. K{sup -}pp{yields}{Lambda}p{yields}p{pi}{sup -}p. an overview of the experiment and the preparation status are reported.

  11. Numerical study of plasma generation process and internal antenna heat loadings in J-PARC RF negative ion source.

    PubMed

    Shibata, T; Nishida, K; Mochizuki, S; Mattei, S; Lettry, J; Hatayama, A; Ueno, A; Oguri, H; Ohkoshi, K; Ikegami, K; Takagi, A; Asano, H; Naito, F

    2016-02-01

    A numerical model of plasma transport and electromagnetic field in the J-PARC (Japan Proton Accelerator Research Complex) radio frequency ion source has been developed to understand the relation between antenna coil heat loadings and plasma production/transport processes. From the calculation, the local plasma density increase is observed in the region close to the antenna coil. Electrons are magnetized by the magnetic field line with absolute magnetic flux density 30-120 Gauss which leads to high local ionization rate. The results suggest that modification of magnetic configuration can be made to reduce plasma heat flux onto the antenna. PMID:26932010

  12. A search for deeply-bound kaonic nuclear state at the J-PARC E15 experiment

    NASA Astrophysics Data System (ADS)

    Ajimura, S.; Beer, G.; Bhang, H.; Bragadireanu, M.; Buehler, P.; Busso, L.; Cargnelli, M.; Choi, S.; Curceanu, C.; Enomoto, S.; Faso, D.; Fujioka, H.; Fujiwara, Y.; Fukuda, T.; Guaraldo, C.; Hashimoto, T.; Hayano, R. S.; Hiraiwa, T.; Iio, M.; Iliescu, M.; Inoue, K.; Ishiguro, Y.; Ishikawa, T.; Ishimoto, S.; Ishiwatari, T.; Itahashi, K.; Iwai, M.; Iwasaki, M.; Kawasaki, S.; Kienle, P.; Kou, H.; Ma, Y.; Marton, J.; Matsuda, Y.; Mizoi, Y.; Morra, O.; Nagae, T.; Noumi, H.; Ohnishi, H.; Okada, S.; Outa, H.; Piscicchia, K.; Poli Lener, M.; Romero Vidal, A.; Sada, Y.; Sakaguchi, A.; Sakuma, F.; Sato, M.; Scordo, A.; Sekimoto, M.; Shi, H.; Sirghi, D.; Sirghi, F.; Suzuki, K.; Suzuki, S.; Suzuki, T.; Tatsuno, H.; Tokuda, M.; Tomono, D.; Toyoda, A.; Tsukada, K.; Vazquez Doce, O.; Widmann, E.; Yamazaki, T.; Yim, H.; Zmeskal, J.

    2013-09-01

    The J-PARC E15 experiment will be performed to search for the simplest kaonic nuclear bound state, KbarNN, by the in-flight He3(K-,N) reaction. The exclusive measurement will be performed by a simultaneous measurement of the missing mass using the forward neutron or proton, and the invariant mass via the expected decay, e.g. K-pp→Λp→pπ-p. In this report, an overview of the experiment and an analysis of engineering runs performed in February and June are presented.

  13. Experimental verification of equilibrium para-hydrogen levels in hydrogen moderators irradiated by spallation neutrons at J-PARC

    NASA Astrophysics Data System (ADS)

    Teshigawara, M.; Harada, M.; Tatsumoto, H.; Aso, T.; Ohtsu, K.; Takada, H.; Futakawa, M.; Ikeda, Y.

    2016-02-01

    By sampling gaseous hydrogen from a circulating liquid hydrogen loop for Laser Raman spectroscopy, we measured the para-/ortho-hydrogen fractions in liquid hydrogen under neutron irradiation for the first time to identify whether irradiated hydrogen has an elevated ortho-hydrogen fraction. This measurement indicates that para-hydrogen equilibrium persists at 300 kW proton power in the presence of an iron(III) oxide hydroxide [Fe(OH)3] catalyst. The measurements will be repeated as the power at the Japan Proton Accelerator Research Complex (J-PARC) increases to the MW level.

  14. SENJU: a new time-of-flight single-crystal neutron diffractometer at J-PARC

    PubMed Central

    Ohhara, Takashi; Kiyanagi, Ryoji; Oikawa, Kenichi; Kaneko, Koji; Kawasaki, Takuro; Tamura, Itaru; Nakao, Akiko; Hanashima, Takayasu; Munakata, Koji; Moyoshi, Taketo; Kuroda, Tetsuya; Kimura, Hiroyuki; Sakakura, Terutoshi; Lee, Chang-Hee; Takahashi, Miwako; Ohshima, Ken-ichi; Kiyotani, Tamiko; Noda, Yukio; Arai, Masatoshi

    2016-01-01

    SENJU is a new single-crystal time-of-flight neutron diffractometer installed at BL18 at the Materials and Life Science Experimental Facility of the Japan Accelerator Research Complex (J-PARC). The diffractometer was designed for precise crystal and magnetic structure analyses under multiple extreme sample environments such as low temperature, high pressure and high magnetic field, and for diffraction measurements of small single crystals down to 0.1 mm3 in volume. SENJU comprises three choppers, an elliptical shape straight supermirror guide, a vacuum sample chamber and 37 scintillator area detectors. The moderator-to-sample distance is 34.8 m, and the sample-to-detector distance is 800 mm. The wavelength of incident neutrons is 0.4–4.4 Å (first frame). Because short-wavelength neutrons are available and the large solid angle around the sample position is covered by the area detectors, a large reciprocal space can be simultaneously measured. Furthermore, the vacuum sample chamber and collimator have been designed to produce a very low background level. Thus, the measurement of a small single crystal is possible. As sample environment devices, a newly developed cryostat with a two-axis (ω and φ axes) goniometer and some extreme environment devices, e.g. a vertical-field magnet, high-temperature furnace and high-pressure cell, are available. The structure analysis of a sub-millimetre size (0.1 mm3) single organic crystal, taurine, and a magnetic structure analysis of the antiferromagnetic phase of MnF2 have been performed. These results demonstrate that SENJU can be a powerful tool to promote materials science research. PMID:26937237

  15. Mass production of the large-sized nuclear plate for J-PARC E07

    NASA Astrophysics Data System (ADS)

    Ito, Hiroki; Nakazama, Kazuma; Hoshino, Kaoru; Yoshida, Jyunya; Tint, Khin Than; Soe, Mint Kyaw; Kinbara, Shinji; Mishina, Akihiro; Endo, Yoko; Kobayashi, Hidetaka; J-PARC E07 Collaboration

    2014-09-01

    In J-PARC E07, about 102 double lambda hypernuclei will be detected, which is 10 times or more than that of the KEK PS-E373 experiment. Therefore, it is necessary for large-scale emulsion plates to avoid time-consuming job for exchange emulsion stack in beam exposure. We also use huge amount of emulsion gel with weight of 2.1 t, which is about 3 times' quantity used for E373. Nuclear emulsion plate is made of photographic emulsion gel as a dry film. Melted gel in 40°C is poured on a thin polystyrene film in the size of 710 × 700 mm2. These sheets were dried slowly for two days in drying cabinet under 28°C and RH. 75%. After drying, the surface was coated by thin gelatin layer with 0.3 μm thickness. Regarding the 2nd face, it was poured and coated in the same manner. Finally we dry it well under 25°C and RH. 60% and cut into four 350 × 345 mm2 plates. We evaluated the performance about these plates. The length of upper, lower, right-hand and left-hand side are 345.08 +/- 0.05 mm, 345.23 +/- 0.13 mm, 350.03 +/- 0.04 mm, and 350.80 +/- 0.05 mm, respectively. The density is 3.676 +/- 0.032 g/cm3, enough quality for the experiment.

  16. Emittance measurements for optimum operation of the J-PARC RF-driven H{sup −} ion source

    SciTech Connect

    Ueno, A. Ohkoshi, K.; Ikegami, K.; Takagi, A.; Yamazaki, S.; Oguri, H.

    2015-04-08

    In order to satisfy the Japan Proton Accelerator Research Complex (J-PARC) second stage requirements of an H{sup −} ion beam of 60mA within normalized emittances of 1.5πmm•mrad both horizontally and vertically, a flat top beam duty factor of 1.25% (500μs×25Hz) and a life-time of longer than 1month, the J-PARC cesiated RF-driven H{sup −} ion source was developed by using an internal-antenna developed at the Spallation Neutron Source (SNS). The transverse emittances of the source were measured with various conditions to find out the optimum operation conditions minimizing the horizontal and vertical rms normalized emittances. The transverse emittances were most effectively reduced by operating the source with the plasma electrode temperature lower than 70°C. The optimum value of the cesium (Cs) density around the beam hole of the plasma electrode seems to be proportional to the plasma electrode temperature. The fine control of the Cs density is indispensable, since the emittances seem to increase proportionally to the excessiveness of the Cs density. Furthermore, the source should be operated with the Cs density beyond a threshold value, since the plasma meniscus shape and the ellipse parameters of the transverse emittances seem to be changed step-function-likely on the threshold Cs value.

  17. New Real-Time PCR Assay Using Locked Nucleic Acid Probes To Assess Prevalence of ParC Mutations in Fluoroquinolone-Susceptible Streptococcus pneumoniae Isolates from France

    PubMed Central

    Decousser, Jean-Winoc; Methlouthi, Imen; Pina, Patrick; Collignon, Anne; Allouch, Pierre

    2006-01-01

    A real-time PCR assay with locked nucleic acid probes was developed to screen mutations at codons 79 and 83 of the Streptococcus pneumoniae parC gene. Only silent mutations were detected among 236 French invasive fluoroquinolone-susceptible strains. This test could be useful for some high-risk patients or in national surveys. PMID:16569894

  18. High-pressure beamline (PLANET) at the spallation neutron source, J-PARC (Invited)

    NASA Astrophysics Data System (ADS)

    Kagi, H.; Hattori, T.; Arima, H.; Utsumi, W. S.; Komatsu, K.; Nagai, T.; Yagi, T.

    2009-12-01

    Material and Life Science experimental Facility (MLF) of Japan Proton Accelerator Research Complex (J-PARC) will be one of the most powerful spallation neutron facilities in the world. The pulsed neutron source with a liquid Hg target is designed to be running at 25 Hz with a power of 1 MW. We have started the construction of the powder diffractometer dedicated to high-pressure experiments (PLANET) on BL-11. PLANET aims to study structures of hydrogen-bearing materials including dense hydrous minerals of the Earth’s deep interior, magmas and light element liquids. The instrument will realize diffraction and radiography experiments for powder and liquid/glass samples at high pressures up to 20 GPa and 2000 K using a large sized multi-anvil hydraulic press that can apply forces of ˜1500 ton. The instrument views a decoupled liquid H2 moderator with a cross section of 100 × 100 mm2. The primary and secondary fight paths are 25 m and 1.5 m, respectively. The 11.5-m-long supermirror guide with elliptical shape starts at a distance of 11.5 m from the moderator. Design of elliptical geometry is optimized by means of incorporating several different grade mirrors and linear approximation with planar guide in order to save cost for production without degradation of the intensity performance. The guide has a rectangular cross-section and consists of four walls coated with supermirror material. Sample is placed at 2 m from the guide exit. The 90° detectors will be installed at 1.5 m from the sample position. For the powder diffraction measurements using a multi-anvil press, an incident neutron beam passes through the vertical anvil gaps and irradiates the sample in the pressure medium. Diffracted neutrons go through the other anvil gaps at 90° direction. Half inch 3He linear position sensitive detectors with 600 mm length will be arranged horizontally and form these detector banks, which cover the scattering angle of 79° ≤ 2θ ≤ 101° and -35° ≤ Φ ≤ +35°. The

  19. Gastrointestinal parasites of mountain gorillas (Gorilla gorilla beringei) in the Parc National des Volcans, Rwanda.

    PubMed

    Sleeman, J M; Meader, L L; Mudakikwa, A B; Foster, J W; Patton, S

    2000-09-01

    Ninety-eight fecal samples were collected from 74 free-living mountain gorillas (Gorilla gorilla beringei) from the Parc National des Volcans, Rwanda, between July 1995 and January 1997 and examined for parasites by Sheather's sugar and zinc sulfate flotation methods, trichrome staining, and larval cultures. All samples contained at least one parasite. Seventeen endoparasites were identified, including eight protozoa, seven nematodes, one cestode, and one trematode. Two species of arthropod mite were also recovered from the fecal samples. Parasites observed on fecal examinations included strongyle/trichostrongyle-type eggs (72/74) (representing Oesphagostomum sp., Trichostrongylus sp., Hyostrongylus spp., and possibly Murshidia sp.), Strongyloides sp. (1/74), Trichuris trichiura (2/74), Probstmayria sp. (7/74), Anoplocephala sp. (63/74), Entamoeba hartmanni cysts and trophozoites (19/70), Endolimax nana cysts (31/70), Iodamoeba buetschlii cysts (11/70), Endolimax nana or Iodamoeba buetschlii trophozoites (63/70). Entamoeba coli cysts and trophozoites (14/70), Entamoeba histolytica trophozoite (1/70), Chilomastix sp. cysts and trophozoites (31/70), and Giardia sp. cysts (2/70). In addition, one ascarid and one trematode egg were seen. There were no significant differences in the prevalence of parasites between males and females and between age groups: however, infants and juveniles appeared to have a lower prevalence of Anoplocephala gorillae, and the silverbacked males appeared to have a higher prevalence of Probstmayria sp. Parasite prevalence was consistent among the five social groups studied except Susa group had a significantly lower prevalence of Anoplocephala gorillae. Trichuris trichiura, Strongyloides sp., Chilomastix sp., and Endolimax nana were identified for the first time in this population, and it is possible that these parasites were of human origin. Although there were no obvious clinical effects due to the presence of these parasites, six parasites

  20. Performance evaluation of a developed orifice type heater for thermal compensation control at J-PARC cryogenic hydrogen system

    NASA Astrophysics Data System (ADS)

    Tatsumoto, H.; Aso, T.; Ohtsu, K.; Kawakami, Y.

    2015-12-01

    Supercritical hydrogen with a temperature of less than 20 K and a pressure of 1.5 MPa is used as moderator material at J-PARC. Total nuclear heating of 3.75 kW is generated by three moderators for a 1-MW proton beam operation. We have developed an orifice-type high-power heater for thermal compensation to mitigate hydrogen pressure fluctuation caused by the abrupt huge heat load and to reduce the fluctuation in the temperature of the supply hydrogen to less than 0.25 K. Through a performance test, we confirmed that the developed orifice-type heater could be heated uniformly and showed fast response, as expected. Furthermore, a simulation model that can describe heater behaviors has been established on the basis of the experimental data. The heater control approach was studied using the aforementioned heater simulation model and a dynamic simulation code developed by the authors.

  1. MARS14 Collimation and Shielding Studies for the 3 GeV Ring of J-PARC Project

    NASA Astrophysics Data System (ADS)

    Nakao, Noriaki; Mokhov, Nikolai; Yamamoto, Kazami; Irie, Yoshiro; Drozhdin, Alexander

    2003-12-01

    MARS14 Monte Carlo simulations were performed for collimation and shielding studies of the J-PARC 3 GeV ring. A 400 MeV proton beam loss distribution, calculated with the STRUCT code, was used as a source term. The module locations in the ring and the curved tunnel sections were described by the MAD-MARS beam line builder and a deep penetration calculation with good statistics was carried out using a 3-dimensional multi-layer technique. Prompt dose-rate distributions were calculated inside and outside the concrete and soil shield, and an effective shielding design was made. The residual dose rates for various beam line materials were also calculated to estimate the external-exposures during maintenance. In this paper, the calculation results are exemplified for the region from the injection through the collimator.

  2. Cryogenic System for J-Parc Neutrino Superconducting Magnet Beam LINE—DESIGN, Construction and Performance Test

    NASA Astrophysics Data System (ADS)

    Makida, Y.; Ohhata, H.; Okamura, T.; Suzuki, S.; Araoka, O.; Ogitsu, T.; Kimura, N.; Nakamoto, T.; Sasaki, K.; Kaneda, S.; Takahashi, T.; Ito, A.; Nagami, M.; Kumaki, T.; Nakashima, T.

    2010-04-01

    A helium cryogenic plant has been constructed in the proton accelerator research complex, J-PARC, to cool a string of superconducting magnets in the neutrino beam line since 2005. It consists of a screw compressor with a capacity of 160 g/s at 1.4 MPa, a 1.5 kW refrigerator, a centrifugal SHE pump with a flow rate of 300 g/s and peripherals. After system integration, performance tests have been carried out. In a preliminary cooling test without magnets, the cryogenic system attained a cooling capacity of 522 W by circulating supercritical helium flow of 300 g/s at 0.4 MPa and at 4.5 K. Afterwards a full system test with the magnets was carried out. The magnets were successfully charged up to an ultimate current of 5000 A beyond a nominal current of 4400 A. This paper describes the plant design and the result of performance measurements.

  3. High-power test of annular-ring coupled structures for the J-PARC linac energy upgrade

    NASA Astrophysics Data System (ADS)

    Tamura, Jun; Ao, Hiroyuki; Nemoto, Yasuo; Asano, Hiroyuki; Suzuki, Takahiro

    2015-02-01

    Annular-ring coupled structures (ACSs) will increase the beam energy of the Japan proton accelerator research complex (J-PARC) linac from 181 to 400 MeV to achieve a beam power of 1 MW for a materials and life science experimental facility. The mass production of the ACS cavities commenced in March 2009. Before the installation, all cavities require power testing. High-power testing is essential not only for confirming the cavity's design performance but also for preventing delays in cavity conditioning schedule. However, the 2011 Tohoku earthquake damaged J-PARC facilities, including the ACS power-test area, and cavity conditioning was interrupted for two years. After the facility's restoration, two ACS cavities (M01 and M11) were conditioned. They performed 15-20% above the designed accelerating field of 4.2 MV/m. As M01 was initially conditioned six years ago, the most recent conditioning time required for M01 was drastically reduced. From this result, we confirmed that long-term stored ACS cavities purged with nitrogen gas do not produce critical cavity performance issues. During high-power operation of M11, which is a unique cavity equipped with a capacitive iris in a waveguide, no significant increases in the temperature and the discharge rate around the capacitive iris were observed. Even considering beam loss due to residual gas scattering, the vacuum pressure was sufficiently low (4 × 10-6 Pa). More stable operation can be expected following a month-long conditioning process before the beam is commissioned. M11's conditioning successfully demonstrated an auto-conditioning program, and we established the conditioning scheme using this auto-conditioning program for all ACS cavities in a limited time and with limited manpower.

  4. Achievement of very low jitter extraction of high power proton beams in the J-PARC RCS

    NASA Astrophysics Data System (ADS)

    Tamura, Fumihiko; Yoshii, Masahito; Schnase, Alexander; Ohmori, Chihiro; Yamamoto, Masanobu; Nomura, Masahiro; Toda, Makoto; Shimada, Taihei; Hara, Keigo; Hasegawa, Katsushi

    2011-08-01

    The 3 GeV rapid cycling synchrotron (RCS) of the Japan Proton Accelerator Research Complex (J-PARC) delivers high intensity proton beams to the Materials and Life Science Facility (MLF) and the main ring (MR). The repetition rate of the RCS is 25 Hz. The typical operation period of the J-PARC is 3.2 s, which consists of 80 RCS cycles. Four beam pulses are for the MR and the other pulses are led into the MLF. Since a bucket-to-bucket injection scheme is used for the MR, the beam from the RCS must be injected with a precise phase to the proper rf bucket of the MR. In case of the MLF, the beam has to be synchronized to the Fermi chopper, which has a tolerance of only a few 100 ns. Thus, stable beam timings with a very low jitter are required for both destinations. To realize the stable beam timing, we employ the timing system, which is not synchronized to the AC power line. Also the magnetic-alloy accelerating cavities and the full digital low-level RF control system are the keys for the precise beam phase control. For acceleration of a high power beam, the phase feedback loop, which damps the longitudinal dipole oscillation, is necessary. The phase loop is a cause of the jitter of the beam extraction timing. We apply a gain pattern of the phase loop to avoid the influence on the beam phase at the extraction. We have achieved a very low jitter extraction of a high power beam within 1.7 ns, which corresponds to 1 degree of the rf frequency at the extraction.

  5. Safety Related Investigations of the VVER-1000 Reactor Type by the Coupled Code System TRACE/PARCS

    NASA Astrophysics Data System (ADS)

    Jaeger, Wadim; Espinoza, Victor Hugo Sánchez; Lischke, Wolfgang

    This study was performed at the Institute of Reactor Safety at the Forschungszentrum Karlsruhe. It is embedded in the ongoing investigations of the international code assessment and maintenance program (CAMP) for qualification and validation of system codes like TRACE(1) and PARCS(2). The chosen reactor type used to validate these two codes was the Russian designed VVER-1000 because the OECD/NEA VVER-1000 Coolant Transient Benchmark Phase 2(3) includes detailed information of the Bulgarian nuclear power plant (NPP) Kozloduy unit 6. The post-test investigations of a coolant mixing experiment have shown that the predicted parameters (coolant temperature, pressure drop, etc.) are in good agreement with the measured data. The coolant mixing pattern, especially in the downcomer, has been also reproduced quiet well by TRACE. The coupled code system TRACE/PARCS which was applied on a postulated main steam line break (MSLB) provided good results compared to reference values and the ones of other participants of the benchmark. The results show that the developed three-dimensional nodalization of the reactor pressure vessel (RPV) is appropriate to describe the coolant mixing phenomena in the downcomer and the lower plenum of a VVER-1000 reactor. This phenomenon is a key issue for investigations of MSLB transient where the thermal hydraulics and the core neutronics are strongly linked. The simulation of the RPV and core behavior for postulated transients using the validated 3D TRACE RPV model, taking into account boundary conditions at vessel in- and outlet, indicates that the results are physically sound and in good agreement to other participant's results.

  6. Validation of the U.S. NRC coupled code system TRITON/TRACE/PARCS with the special power excursion reactor test III (SPERT III)

    SciTech Connect

    Wang, R. C.; Xu, Y.; Downar, T.; Hudson, N.

    2012-07-01

    The Special Power Excursion Reactor Test III (SPERT III) was a series of reactivity insertion experiments conducted in the 1950's. This paper describes the validation of the U.S. NRC Coupled Code system TRITON/PARCS/TRACE to simulate reactivity insertion accidents (RIA) by using several of the SPERT III tests. The work here used the SPERT III E-core configuration tests in which the RIA was initiated by ejecting a control rod. The resulting super-prompt reactivity excursion and negative reactivity feedback produced the familiar bell shaped power increase and decrease. The energy deposition during such a power peak has important safety consequences and provides validation basis for core coupled multi-physics codes. The transients of five separate tests are used to benchmark the PARCS/TRACE coupled code. The models were thoroughly validated using the original experiment documentation. (authors)

  7. Accessing proton generalized parton distributions and pion distribution amplitudes with the exclusive pion-induced Drell-Yan process at J-PARC

    NASA Astrophysics Data System (ADS)

    Sawada, Takahiro; Chang, Wen-Chen; Kumano, Shunzo; Peng, Jen-Chieh; Sawada, Shinya; Tanaka, Kazuhiro

    2016-06-01

    Generalized parton distributions (GPDs) encoding multidimensional information of hadron partonic structure appear as the building blocks in a factorized description of hard exclusive reactions. The nucleon GPDs have been accessed by deeply virtual Compton scattering and deeply virtual meson production with lepton beam. A complementary probe with hadron beam is the exclusive pion-induced Drell-Yan process. In this paper, we discuss recent theoretical advances on describing this process in terms of nucleon GPDs and pion distribution amplitudes. Furthermore, we address the feasibility of measuring the exclusive pion-induced Drell-Yan process π-p →μ+μ-n via a spectrometer at the High Momentum Beamline being constructed at J-PARC in Japan. Realization of such measurement at J-PARC will provide a new test of perturbative QCD descriptions of a novel class of hard exclusive reactions. It will also offer the possibility of experimentally accessing nucleon GPDs at large timelike virtuality.

  8. Rapid detection of gyrA and parC mutations in fluoroquinolone-resistant Neisseria gonorrhoeae by denaturing high-performance liquid chromatography.

    PubMed

    Shigemura, Katsumi; Shirakawa, Toshiro; Okada, Hiroshi; Tanaka, Kazushi; Udaka, Tohru; Kamidono, Sadao; Arakawa, Soichi; Gotoh, Akinobu

    2004-12-01

    The detection of DNA sequence variation is fundamental to the identification of the genomic basis of phenotypic variability. Denaturing high-performance liquid chromatography (DHPLC) is a novel technique that is used to detect mutations in human DNA. This is the first report that this technique is used as a tool to detect mutations in genes encoding fluoroquinolone resistance in Neisseria gonorrhoeae. Eighty-one strains of N. gonorrhoeae were used in this study. Genomic DNA from each strain was subjected to PCR amplification of 225 bp in gyrA and 166 bp in parC spanning the fluoroquinolone-resistance determining regions (QRDRs). After we performed DNA sequencing of these amplicons and identification of mutations in the QRDRs, DHPLC was undertaken to investigate whether its results correlate the distinctive chromatogram with their DNA mutations pattern. The profilings detected by DHPLC completely corresponded to the results of the DNA sequencing in mutation patters in gyrA and parC genes. They resulted in the following amino acid substitutions: Ser-91Phe, Asp-95Gly, and Asp-95Asn in gyrA; and Gly-85Asp, Asp-86Asn, Ser-87Arg, and Ser-88Pro in parC, respectively. These mutations existed alone or as combinations, and we identified five mutations patterns in gyrA and six in parC including wild-type. These mutations and their patterns could be rapidly and reproducibly identified from the PCR products using DHPLC, producing specific peak patterns that correlate with genotypes. This novel detection system facilitates the detection of resistance alleles, providing a rapid (5 min per sample), economic (96 sample per run), and reliable technique for characterizing fluoroquinolone resistance in N. gonorrhoeae. PMID:15488283

  9. A search for the K-pp bound state in the 3He(K-in-flight, n) reaction at J-PARC

    NASA Astrophysics Data System (ADS)

    Hashimoto, T.; Ajimura, S.; Beer, G.; Bhang, H.; Bragadireanu, M.; Buehler, P.; Busso, L.; Cargnelli, M.; Choi, S.; Curceanu, C.; Enomoto, S.; Faso, D.; Fujioka, H.; Fujiwara, Y.; Fukuda, T.; Guaraldo, C.; Hayano, R. S.; Hiraiwa, T.; Iio, M.; Iliescu, M.; Inoue, K.; Ishiguro, Y.; Ishikawa, T.; Ishimoto, S.; Ishiwatari, T.; Itahashi, K.; Iwai, M.; Iwasaki, M.; Kato, Y.; Kawasaki, S.; Kienle, P.; Kou, H.; Ma, Y.; Marton, J.; Matsuda, Y.; Mizoi, Y.; Morra, O.; Nagae, T.; Noumi, H.; Ohnishi, H.; Okada, S.; Outa, H.; Piscicchia, K.; Poli Lener, M.; Romero Vida, A.; Sada, Y.; Sakaguchi, A.; Sakuma, F.; Sato, M.; Scordo, A.; Sekimoto, M.; Shi, H.; Sirghi, D.; Sirghi, F.; Suzuki, K.; Suzuki, S.; Suzuki, T.; Tanida, K.; Tatsuno, H.; Tokuda, M.; Tomono, D.; Toyoda, A.; Tsukada, K.; Vazquez Doce, O.; Widmann, E.; Wuenschek, B. K.; Yamaga, T.; Yamazaki, T.; Yim, H.; Zhang, Q.; Zmeska, J.

    2014-03-01

    We have collected the first physics data of an experimental search for the simplest kaonic nuclear bound state, "K- pp", by the 3He(K- n) reaction at J-PARC. We confirmed that our spectrometer system works as designed and observed clear peak structure composed of the quasi-elastic K-"n" → K-n and the charge-exchange K-"p" → ¯̅K0n reactions in the forward neutron spectrum.

  10. Insertion sequence disruption of adeR and ciprofloxacin resistance caused by efflux pumps and gyrA and parC mutations in Acinetobacter baumannii.

    PubMed

    Lopes, B S; Amyes, S G B

    2013-02-01

    Acinetobacter baumannii is a pathogenic bacterium responsible for a wide range of infections in immunocompromised patients. This study examined the role of insertional inactivation of the adeR gene and its effect on adeABC gene expression along with characterisation of the gyrA and parC mutations involved in ciprofloxacin resistance in three A. baumannii clinical isolates and their derivatives. Primers designed for the detection of adeSRABC detected the presence of ISAba16, which disrupted the adeR gene in strain Ab12M, and ISAba1, which disrupted the same gene in strains Ab18 and Ab209. A second copy of ISAba1 was detected upstream of the adeA gene in Ab209 leading to AdeABC pump expression. AdeIJK pump expression was seen in all of the isolates but was not as significant as AdeABC expression. Minimum inhibitory concentrations of ciprofloxacin were ≥256 mg/L for all of the isolates and a decrease of ≥8-fold was seen following addition of the efflux pump inhibitor 1-(1-naphthylmethyl)-piperazine. Fluorometric analysis also demonstrated active efflux, with upregulation of adeIJK and some genes of the adeABC operon in some strains. Sequencing of the quinolone resistance-determining region of the gyrA and parC genes revealed a Ser83→Leu change in the gyrA gene and a novel change of Ser80→Trp in the parC gene of Ab12, Ab12M and Ab209; in Ab18 there was a Ser80→Leu change in parC. This study shows the multifactorial contribution of different mechanisms in A. baumannii leading to ciprofloxacin resistance. PMID:23217848

  11. Fluoroquinolone resistance and molecular characterization of gyrA and parC quinolone resistance-determining regions in Escherichia coli isolated from poultry.

    PubMed

    Vanni, M; Meucci, V; Tognetti, R; Cagnardi, P; Montesissa, C; Piccirillo, A; Rossi, A M; Di Bello, D; Intorre, L

    2014-04-01

    Escherichia coli are a common inhabitant of the gastrointestinal tract of mammals and birds; nevertheless, they may be associated with a variety of severe and invasive infections. Whereas fluoroquinolones (FQ) have been banned in the United States for use in poultry production, the use of these antimicrobials in poultry husbandry is still possible in the European Union, although with some restrictions. The aim of this study was to investigate the FQ resistance of 235 E. coli isolates recovered from chickens and turkeys. Minimum inhibitory concentrations were determined by a microdilution method, whereas mutations in the quinolone resistance-determining regions of the target genes, gyrA and parC, were detected by a PCR-based method. High resistance rates (>60%) were observed for nalidixic acid, flumequine, and difloxacin, whereas resistance to ciprofloxacin, danofloxacin, enrofloxacin, marbofloxacin, and sarafloxacin was less frequently reported (<40%). Sixty-four isolates (27.2%) showed full susceptibility toward the tested FQ, but 57 isolates (24.2%) were resistant to all tested FQ. The remaining 114 E. coli isolates (48.5%) were grouped in 5 different resistance patterns. Isolates resistant only to flumequine or nalidixic acid or both possessed 1 gyrA mutation, whereas isolates with further resistance to enrofloxacin, difloxacin, danofloxacin, and sarafloxacin had in addition 1 or 2 parC substitutions. Two gyrA mutations coupled with 1 substitution in parC were detected in isolates resistant to all tested FQ. The number of mutations and their correlation with the in vitro activity of FQ reflected the currently accepted model, according to which a single gyrA substitution is associated with resistance or decreased susceptibility to older quinolones, whereas further gyrA or parC substitutions are needed for a higher level of resistance. PMID:24706962

  12. Fluoroquinolone Resistance Linked to GyrA, GyrB, and ParC Mutations in Salmonella enterica Typhimurium Isolates in Humans

    PubMed Central

    Casin, Isabelle; Breuil, Jacques; Darchis, Jean Pierre; Guelpa, Claire

    2003-01-01

    We report two cases of infection with clonally unrelated, high-level ciprofloxacin-resistant, β-lactamase–producing strains of Salmonella enterica Typhimurium. Resistance was caused by four topoisomerase mutations, in GyrA, GyrB, and ParC and increased drug efflux. Ciprofloxacin treatment failed in one case. In the second case, reduced susceptibility to third-generation cephalosporins occurred after initial treatment with these drugs and may explain the treatment failure with ceftriaxone.

  13. Resistance Mutations in gyrA and parC are Common in Escherichia Communities of both Fluoroquinolone-Polluted and Uncontaminated Aquatic Environments

    PubMed Central

    Johnning, Anna; Kristiansson, Erik; Fick, Jerker; Weijdegård, Birgitta; Larsson, D. G. Joakim

    2015-01-01

    Alterations in the target proteins of fluoroquinolones, especially in GyrA and ParC, are known to cause resistance. Here, we investigated environmental Escherichia communities to explore the possible link between the abundance of mutations, and the exposure to fluoroquinolones. Sediment samples were collected from a relatively pristine lake, up and downstream from a sewage treatment plant, and from several industrially polluted sites. The quinolone resistance-determining regions of gyrA and parC were analyzed using amplicon sequencing of metagenomic DNA. Five non-synonymous substitutions were present in all samples, and all of these mutations have been previously linked to fluoroquinolone resistance in Escherichia coli. In GyrA, substitutions S83L and D87N were on average detected at frequencies of 86 and 32%, respectively, and 31% of all amplicons encoded both substitutions. In ParC, substitutions S80I, E84G, and E84V were detected in 42, 0.9, and 6.0% of the amplicons, respectively, and 6.5% encoded double substitutions. There was no significant correlation between the level of fluoroquinolone pollution and the relative abundance of resistance mutations, with the exception of the most polluted site, which showed the highest abundance of said substitutions in both genes. Our results demonstrate that resistance mutations can be common in environmental Escherichia, even in the absence of a fluoroquinolone selective pressure. PMID:26696975

  14. Association of mutation patterns in GyrA and ParC genes with quinolone resistance levels in lactic acid bacteria.

    PubMed

    Li, Shaoying; Li, Zhen; Wei, Wan; Ma, Chunyan; Song, Xiaomin; Li, Shufen; He, Wenying; Tian, Jianjun; Huo, Xiaoyan

    2015-02-01

    The quinolone resistance of 19 lactic acid bacterial strains belonging to the genera Enterococcus and Lactobacillus isolated from the natural fermented koumiss and yoghurt were investigated. The objective of this study was to determine the quinolone resistance levels and to explore the association of the resistance with the mutation patterns in gyrA and parC genes, as is currently recommended by the Food and Agriculture Organization/World Health Organization Joint Expert Committee in Guidelines for Evaluation of Probiotics in Food for probiotic lactic acid bacteria drug resistance in 2001. The Oxford Cup method and double-tube dilution method were used to determine the quinolone resistance levels of the isolated strains. Generally, all of the 19 strains showed resistance towards norfloxacin and ciprofloxacin when the Oxford cup method was used, whereas the incidence was lower (to norfloxacin 89.5% and to ciprofloxacin 68.4%) when minimum inhibitory concentration breakpoints (CLSI M100-S23) were tested. Furthermore, gene sequencing was conducted on gyrA and parC of topoisomerase II of these isolated strains. The genetic basis for quinolone resistance may be closely related to mutations in gyrA genes as there were 10 mutation sites in amino-acid sequences encoded by gyrA genes in 10 quinolone resistance strains and 14 mutation sites in Enterococcus durans HZ28, whereas no typical mutations were detected in parC genes. PMID:25204345

  15. Rapid detection of Escherichia coli gyrA and parC mutants in one-day-old broiler chicks in Iran.

    PubMed

    Abdi-Hachesoo, Bahman; Asasi, Keramat; Sharifiyazdi, Hassan

    2013-01-01

    Vertical and consequently horizontal transmission of quinolone and fluoroquinolone resistant Escherichia coli clones following hatch in chickens enables a massive amplification of these clones into a large population. The aim of this study was to determine the antibiotic resistance and susceptibility of Iranian E. coli isolates (n=105) from one-day-old chicks to fluoroquinolones and the relation of this resistance with mutations in gyrA and parC genes using PCR-RFLP. For the first time, EcoRV restriction enzyme was used for rapid mutation screening in parC (Ser80Ile). The results showed that the low level of Minimum Inhibitory Concentration (MIC) for ciprofloxacin (0.25-4μg ml-1) and enrofloxacin (0.25-4μg ml-1) corresponded to a single mutation in gyrA, while intermediary to high level of MIC for ciprofloxacin (8 --> 64 μg ml-1) and enrofloxacin (16 --> 64 μg ml-1) were related to 2 mutations in gyrA or 3 mutations, 2 in gyrA and 1 in parC. There was a strong positive correlation (R = 0.93, P < 0.001) between MIC levels of enrofloxacin and ciprofloxacin among these isolates. The article concludes by stressing that the rising incidence of enrofloxacin resistant E. coli isolates from chicken sources may increase the potential risk of ciprofloxacin resistant E. coli acquisition by humans. PMID:24358491

  16. Mutant Prevention Concentrations for Single-Step Fluoroquinolone-Resistant Mutants of Wild-Type, Efflux-Positive, or ParC or GyrA Mutation-Containing Streptococcus pneumoniae Isolates

    PubMed Central

    Smith, Heather J.; Walters, Michael; Hisanaga, Tamiko; Zhanel, George G.; Hoban, Daryl J.

    2004-01-01

    Three fluoroquinolone-susceptible and five fluoroquinolone-resistant (two with ParC Ser79Phe mutations, one with a GyrA Ser81Phe mutation, and two that were efflux positive) Streptococcus pneumoniae isolates were exposed to one, two, four, eight, and sixteen times the MICs of ciprofloxacin, gatifloxacin, gemifloxacin, levofloxacin, and moxifloxacin. Mutational frequencies were calculated at each multiple of the MIC for which growth was observed. Mutant prevention concentrations (MPCs) and the multiple of the MIC at the MPC (MPMIC) were evaluated. All resulting mutants were sequenced for quinolone resistance-determining region changes in GyrA and ParC and were evaluated for reserpine-sensitive efflux. The MPC order was generally ciprofloxacin > levofloxacin > gatifloxacin > moxifloxacin > gemifloxacin. The MPMIC order varied depending on the genetic constitution of the original isolates from which the mutants were generated. For those mutants created from fluoroquinolone-susceptible isolates (those that had wild-type ParC and GyrA and were efflux negative), the MPMIC order was ciprofloxacin = moxifloxacin > gemifloxacin > levofloxacin > gatifloxacin. The MPMICs of each fluoroquinolone for mutants created from isolates with a ParC mutation (with wild-type GyrA and efflux negative) were similar. A similar occurrence was observed with the mutants created from the efflux-positive isolates (with wild-type ParC and GyrA). The MPMIC order for the mutants created from the isolate with a GyrA mutation (with wild-type ParC and efflux negative) was ciprofloxacin = gemifloxacin > levofloxacin = moxifloxacin > gatifloxacin. Gatifloxacin, levofloxacin, and moxifloxacin may be intrinsically more able to prevent the development of resistance by fluoroquinolone-susceptible isolates, isolates that are efflux positive, or isolates that carry a GyrA mutation. However, once a ParC mutation is present, the MPC increases dramatically for all fluoroquinolones. PMID:15388458

  17. Apprenez la Science en Francais?

    ERIC Educational Resources Information Center

    Edmonds, Juliet; Jacobs, Pippa

    2011-01-01

    The authors explain why integrating the teaching of science and French is not as ridiculous as it may at first sound. They describe how this innovative integrated approach works in a primary school in Oxfordshire. The project involves Content and Language Integrated Learning (CLIL). CLIL is a method whereby a curriculum subject is planned and…

  18. Design Result of the Cryogenic Hydrogen Circulation System for 1 MW Pulse Spallation Neutron Source (JSNS) in J-PARC

    SciTech Connect

    Aso, T.; Tatsumoto, H.; Hasegawa, S.; Ushijima, I.; Ohtsu, K.; Kato, T.; Ikeda, Y.

    2006-04-27

    A cryogenic hydrogen circulation system to cool cryogenic hydrogen moderators for the spallation neutron source in J-PARC has been designed. This system consists of a helium refrigerator system and a hydrogen circulation system. The refrigeration capacity required for the cryogenic system is specified to be around 6 kW at 17 K. The hydrogen circulation system is composed of a hydrogen-helium heat exchanger, two circulation pumps, multiple transfer lines, three moderator vessels, an Ortho-Para hydrogen converter, an accumulator, a heater and others. The system adopts a centrifugal-type hydrogen pump that can circulate the cryogenic hydrogen (20 K, 0.5 to 1.5 MPa) with the mass flow up to 162 g/s through the three moderators. This forced-flow circulation can remove the nuclear heating from the moderators and can keep the temperature difference through the moderators within 3 K. The Ortho-Para hydrogen converter will be installed to maintain the Para-hydrogen concentration of more than 99% at the inlet of the moderators. For the pressure changes due to the proton beam being turned on and off, we will prepare an accumulator and a heater, which is called a hybrid pressure control. The cryogenic system has been designed with safety concepts that protect the public.

  19. Performance of a superconducting magnet system operated in the Super Omega Muon beam line at J-PARC

    SciTech Connect

    Makida, Yasuhiro; Ikedo, Yutaka; Ogitsu, Toru; Shimomura, Koichiro; Miyake, Yasuhiro; Yoshida, Makoto; Adachi, Taihei; Kadono, Ryosuke; Kawamura, Naritoshi; Strasser, Patric; Koda, Akihiro; Fujimori, Hiroshi; Nishiyama, Kusuo; Ohhata, Hirokatsu; Okamura, Takahiro; Okada, Ryutaro; Orikasa, Tomofumi

    2014-01-29

    A superconducting magnet system, which is composed of an 8 m long solenoid for transportation and 12 short solenoids for focusing, has been developed for Muon Science Establishment facility of J-PARC. The transport solenoid is composed of a 6 m straight section connected to a 45 degree curved section at each end. Muons of various momenta and of both electric charges are transported through the solenoid inner bore with an effective diameter of 0.3 m, where 2 T magnetic field is induced. There are 12 focusing solenoids with an effective bore diameter of 0.6 m and a length of 0.35 m arranged on a straight line at suitable intervals. The maximum central field of each focusing solenoid is 0.66 T. All solenoid coils are cooled by GM cryocoolers through their own conductions. The magnet system has been installed into the beam line in the summer of 2012, and its performance has been checked. Beam commissioning has been carried out since October 2012. During beam operation, temperature rise over 6 K in the transport solenoid due to a nuclear heating from the muon production target is observed at beam intensity of about 300 kW.

  20. Analysis of the Peach Bottom Turbine Trip 2 Experiment by Coupled RELAP5-PARCS Three-Dimensional Codes

    SciTech Connect

    Bousbia-Salah, Anis; Vedovi, Juswald; D'Auria, Francesco; Ivanov, Kostadin; Galassi, Giorgio

    2004-10-15

    Thanks to continuous progress in computer technology, it is now possible to perform best-estimate simulations of complex scenarios in nuclear power plants. This method is carried out through the coupling of three-dimensional (3-D) neutron modeling of a reactor core into system codes. It is particularly appropriate for transients that involve strong interactions between core neutronics and reactor loop thermal hydraulics. For this purpose, the Peach Bottom boiling water reactor turbine trip test was selected to challenge the capability of such coupled codes. The test is characterized by a power excursion induced by rapid core pressurization and a self-limiting course behavior. In order to perform the closest simulation, the coupled thermal-hydraulic system code RELAP5 and 3-D neutron kinetic code PARCS were used. The obtained results are compared to those available from experimental data. Overall, the coupled code calculations globally predict the most significant observed aspects of the transient, such as the pressure wave amplitude across the core and the power course, with an acceptable agreement. However, sensitivity studies revealed that more-accurate code models should be considered in order to better match the void dynamic and the cross-section variations during transient conditions.

  1. The new experiment WAGASCI for water to hydrocarbon neutrino cross section measurement using the J-PARC beam

    NASA Astrophysics Data System (ADS)

    Ovsiannikova, T.; Antonova, M.; Bronner, C.; Blondel, A.; Bonnemaison, A.; Cornat, R.; Cadoux, F.; Chikuma, N.; Cao, S.; Drapier, O.; Izmaylov, A.; Ichikawa, A. K.; Ferreira, O.; Favre, Y.; Gastaldi, F.; Gonin, M.; Hayashino, T.; Hosomi, F.; Hayato, Y.; Koga, T.; Kondo, K.; Kin, K.; Kudenko, Y.; Khabibullin, M.; Khotjantsev, A.; Minamino, A.; Mueller, Th A.; Mefodiev, A.; Mineev, O.; Nakamura, K.; Nakaya, T.; Noah, E.; Patel, N.; Quilain, B.; Rayner, M.; Seiya, Y.; Suvorov, S.; Yershov, N.; Yamamoto, M.; Yamamoto, K.; Yokoyama, M.

    2016-02-01

    The T2K (Tokai-to-Kamioka) is a long baseline neutrino experiment designed to study various parameters that rule neutrino oscillations, with an intense beam of muon neutrinos. A near detector complex (ND280) is used to constrain non-oscillated flux and hence to predict the expected number of events in the far detector (Super-Kamiokande). The difference in the target material between the far (water) and near (scintillator, hydrocarbon) detectors leads to the main non-canceling systematic uncertainty for the oscillation analysis. In order to reduce this uncertainty a new water grid and scintillator detector, WAGASCI, has been proposed. The detector will be operated at the J-PARC neutrino beam line with the main physics goal to measure the charged current neutrino cross section ratio between water and hydrocarbon with a few percent accuracy. Further physics program may include high-precision measurements of different charged current neutrino interaction channels. The concept of the new detector will be covered together with the actual construction plan.

  2. Pressure Rise Analysis When Hydrogen Leak from a Cracked Pipe in the Cryogenic Hydrogen System in J-PARC

    NASA Astrophysics Data System (ADS)

    Tatsumoto, H.; Aso, T.; Hasegawa, S.; Ushijima, I.; Kato, T.; Ohtsu, K.; Ikeda, Y.

    2006-04-01

    As one of the main experimental facilities in the Japan Proton Accelerator Research Complex (J-PARC), an intense spallation neutron source (JSNS) driven by a 1 MW proton beam is being constructed. Cryogenic hydrogen at supercritical pressure is selected as a moderator. The total nuclear heating at the moderators is estimated to be a 3.7 kW. A hydrogen system to cool the moderators has been designed. The most severe off-normal event for the cryogenic hydrogen system is considered to be a hydrogen leak when a pipe cracks. In such a case, the hydrogen must be discharged to atmosphere quickly and safely. An analytical code that simulates the pressure change during a hydrogen leak was developed. A pressure rise analysis for various sized cracks was performed, and the required sizes for relief devices were determined. A safety valve size is φ42.7 mm and a rupture disc for vacuum layer should have a diameter of 37.1 mm, respectively.

  3. Pressure Rise Analysis When Hydrogen Leak from a Cracked Pipe in the Cryogenic Hydrogen System in J-PARC

    SciTech Connect

    Tatsumoto, H.; Aso, T.; Hasegawa, S.; Ushijima, I.; Kato, T.; Ohtsu, K.; Ikeda, Y.

    2006-04-27

    As one of the main experimental facilities in the Japan Proton Accelerator Research Complex (J-PARC), an intense spallation neutron source (JSNS) driven by a 1 MW proton beam is being constructed. Cryogenic hydrogen at supercritical pressure is selected as a moderator. The total nuclear heating at the moderators is estimated to be a 3.7 kW. A hydrogen system to cool the moderators has been designed. The most severe off-normal event for the cryogenic hydrogen system is considered to be a hydrogen leak when a pipe cracks. In such a case, the hydrogen must be discharged to atmosphere quickly and safely. An analytical code that simulates the pressure change during a hydrogen leak was developed. A pressure rise analysis for various sized cracks was performed, and the required sizes for relief devices were determined. A safety valve size is {phi}42.7 mm and a rupture disc for vacuum layer should have a diameter of 37.1 mm, respectively.

  4. High-resolution search for the Θ+ pentaquark via a pion-induced reaction at J-PARC

    NASA Astrophysics Data System (ADS)

    Moritsu, M.; Adachi, S.; Agnello, M.; Ajimura, S.; Aoki, K.; Bhang, H. C.; Bassalleck, B.; Botta, E.; Bufalino, S.; Chiga, N.; Ekawa, H.; Evtoukhovitch, P.; Feliciello, A.; Fujioka, H.; Hayakawa, S.; Hiruma, F.; Honda, R.; Hosomi, K.; Ichikawa, Y.; Ieiri, M.; Igarashi, Y.; Imai, K.; Ishibashi, N.; Ishimoto, S.; Itahashi, K.; Iwasaki, R.; Joo, C. W.; Kanatsuki, S.; Kim, M. J.; Kim, S. J.; Kiuchi, R.; Koike, T.; Komatsu, Y.; Kulikov, V. V.; Marcello, S.; Masumoto, S.; Matsumoto, Y.; Matsuoka, K.; Miwa, K.; Nagae, T.; Naruki, M.; Niiyama, M.; Noumi, H.; Nozawa, Y.; Ota, R.; Ozawa, K.; Saito, N.; Sakaguchi, A.; Sako, H.; Samoilov, V.; Sato, M.; Sato, S.; Sato, Y.; Sawada, S.; Sekimoto, M.; Shirotori, K.; Sugimura, H.; Suzuki, S.; Takahashi, H.; Takahashi, T.; Takahashi, T. N.; Tamura, H.; Tanaka, T.; Tanida, K.; Tokiyasu, A. O.; Tomida, N.; Tsamalaidze, Z.; Ukai, M.; Yagi, K.; Yamamoto, T. O.; Yang, S. B.; Yonemoto, Y.; Yoon, C. J.; Yoshida, K.; J-PARC E19 Collaboration

    2014-09-01

    The pentaquark Θ+ has been searched for via the π-p→K-X reaction with beam momenta of 1.92 and 2.01 GeV/c at J-PARC. A missing mass resolution of 2 MeV (FWHM) was achieved but no sharp peak structure was observed. The upper limits on the production cross section averaged over the scattering angle from 2∘ to 15∘ in the laboratory frame were found to be less than 0.28 μb/sr at the 90% confidence level for both the 1.92- and 2.01-GeV/c data. The systematic uncertainty of the upper limits was controlled within 10%. Constraints on the Θ+ decay width were also evaluated with a theoretical calculation using an effective Lagrangian. The present result implies that the width should be less than 0.36 and 1.9 MeV for the spin-parity of 1/2+ and 1/2-, respectively.

  5. Development of a highly segmented scintillator hodoscope to construct intelligent trigger system for J-PARC E07

    NASA Astrophysics Data System (ADS)

    Oue, Kenichiro; Ekawa, Hiroyuki; Hwang, Sanghoon; Hosomi, Kenji; Hayakawa, Shuhei; Sakaguchi, Atsushi

    2014-09-01

    The purposes of J-PARC E07 are a systematic study of double Lambda hypernuclei with 10 times higher yields than the previous experiment (KEK-E373) and the first measurement of Ξ- atomic X-rays. In the experiment, we produce Ξ- via the quasi-free (K-,K+) reaction off a diamond target and expect to observe 104 stopped Ξ- (Ξ- atoms) in the emulsion counters. The (K-,K+) reaction is measured by using the KURAMA spectrometer and the acceptance of the KURAMA spectrometer is enlarged from the KEK-E373 experiment. So, a sophisticated online trigger system is inevitable to operate the new KURAMA spectrometer. We employ an intelligent three-dimensional matrix trigger system with a fine-beam-hodoscope (FBH), a highly segmented charge-hodoscope (CH) and a time-of-flight wall (TOF). The FBH is placed in the beamline, whereas CH is located at the upstream of the KURAMA magnet and TOF is located at the most downstream. The highly segmented CH consists of 64 segments, and each segment is made of a plastic scintillator 2 mm thickness, 11.5 mm width and 450 mm length. Scintillation light signals are read out with a wave-length-shifting fiber. Multi-pixel photon counters and front-end read-out EASIROC boards are used. The performance of CH is evaluated by using positron beams and cosmic rays. I will present the results of the performance studies of CH.

  6. Design of a neutron polarizer using polarizing super mirrors for the TOF-SANS instrument at the J-PARC

    NASA Astrophysics Data System (ADS)

    Shinohara, Takenao; Suzuki, Jun-ichi; Oku, Takayuki; Takata, Shin-ichi; Kira, Hiroshi; Suzuya, Kentaro; Aizawa, Kazuya; Arai, Masatoshi; Otomo, Toshiya; Sugiyama, Masaaki

    2009-09-01

    Small-angle neutron scattering technique using polarized neutrons is powerful for studying structures in the range between nm and μm of magnetic materials. In addition, they have been used for the incident beam of focusing-geometry SANS instruments using a magnetic neutron lens, where a high polarization degree of about 99.9% is necessary because the imperfectness of the neutron polarization increases the background level. We are going to install such a magnetic focusing system on the new time-of-flight SANS (TOF-SANS) instrument at the J-PARC so as to make q min smaller than 10 -3 Å -1 and improve the resolution of the conventional TOF-SANS at low q. As a polarizing device of the instrument, two V-shaped polarizing super mirrors arranged in crossed geometry to enhance the polarization degree has been considered. In this paper, we present the concept and the detailed design of this device and its performance estimated by Monte Carlo simulations.

  7. Development of a liquid 3He target for experimental studies of antikaon-nucleon interaction at J-PARC

    NASA Astrophysics Data System (ADS)

    Iio, M.; Ishimoto, S.; Sato, M.; Enomoto, S.; Hashimoto, T.; Suzuki, S.; Iwasaki, M.; Hayano, R. S.

    2012-09-01

    A liquid 3He target system was developed for experimental studies of kaonic atoms and kaonic nuclei at J-PARC. 3He gas is liquefied in a heat exchanger cooled below 3.2 K by decompression of liquid 4He. To maintain a large acceptance of the cylindrical detector system for decay particles of kaonic nuclei, efficient heat transport between the separate target cell and the main unit is realized using circulation of liquid 3He. To minimize the amount of material, a vacuum vessel containing a carbon fiber reinforced plastic cylinder having an inside diameter of 150 mm and a thickness of 1 mm was produced. A target cell made of pure beryllium and beryllium-aluminum alloy was developed not only to minimize the amount of material but also to obtain high X-ray transmission. During a cooling test, the target cell was kept at 1.3 K at a pressure of 33 mbar. The total estimated heat load to the components including the target cell and heat exchanger cooled by liquid 4He decompression, was 0.21 W, and the liquid 4He consumption rate was 50 L/day.

  8. J-PARC MUSE H-line optimization for the g-2 and MuHFS experiments

    NASA Astrophysics Data System (ADS)

    Toyoda, A.; Fujiwara, Y.; Fukao, Y.; Kamigaito, O.; Kawamura, N.; Matsuda, Y.; Mibe, T.; Ogitsu, T.; Saito, N.; Sasaki, K.; Shimomura, K.; Sugano, M.; Tanaka, K.; Tomono, D.; Torii, H. A.

    2013-02-01

    Significant deviation of the anomalous magnetic moment value (g-2) observed by the muon g-2 experiment [1] should be confirmed by the other experiment. This value is experimentally determined by frequency difference observed by the g-2/EDM experiment and muon magnetic moment observed by the muonium hyperfine splitting experiment (MuHFS). Both two experiments are planned to be performed at H-line of the J-PARC/MUSE under construction. We optimized the beamline layout for each experiment with G4beamline [5]. For both experiments, statistics is the most important, thus beamline transmission efficiency should be maximized. Especially for the g-2, the purpose of the present effort is to compromise between small beam size and small leakage field. For the MuHFS, it is crucial to minimize leakage field at around final focus position, and to get all stopped muons within good field region of MuHFS magnet. Conceptual design of the several final focusing systems will be presented.

  9. Improvement of Vacuum Pressure in the Annular-Ring Coupled Structures for the J-PARC Linac

    NASA Astrophysics Data System (ADS)

    Ao, Hiroyuki; Nemoto, Yasuo; Oozone, Akira; Tamura, Jun

    The accelerating cavities of the J-PARC linac, additionally comprising an annular-ring-coupled structure (ACS), went into operation in 2014. To further improve the vacuum pressure of the ACS, an additional nonevaporable getter (NEG) pump was designed so that it could be installed independent of the vacuum chamber of the ACS cavity. We confirmed that the NEG pump can be appropriately activated by using a small pumping station and that purging with noble gases reduces the saturation of the NEG surface. In the evacuation test of the prototype ACS cavity with the NEG pump, the partial pressure of H2 and the total pressure were reduced from 4.8 × 10-7 and 6.8 × 10-7 Pa to 2.5 × 10-7 and 4.5 × 10-7 Pa, respectively. The additional NEG pump will be installed in the ACS cavity in the fall of 2014, after which any decrease in pressure and NEG-pump lifetime will be confirmed by long-term-operation experiments.

  10. The Hippoboscidae (Insecta: Diptera) from Madagascar, with new records from the “Parc National de Midongy Befotaka”

    PubMed Central

    Rahola, N.; Goodman, S.M.; Robert, V.

    2011-01-01

    The Hippoboscidae or “louse-flies” is a family of pupiparous Diptera, which in their adult stage are ectoparasites of mammals and birds. This paper presents a comprehensive review of Malagasy Hippoboscidae. In total, amongst the 213 species of this family known worldwide, 14 have been reported in Madagascar, among which six are considered as endemic to the Malagasy region. In addition, data are presented from a collection of 17 Hippoboscidae obtained from seven species of forest-dwelling birds in the “Parc National de Midongy Befotaka”, southeastern Madagascar, in 2003. The flies in this collection belong to three different species: Icosta malagasii (one), Ornithoica podicipis (ten) and Ornithoctona laticornis (six). The two former species were previously only known from single specimens in museum collections; the later species is distributed across much of the Afrotropical region and the records presented herein are the first for Madagascar. All the seven bird species are new hosts for hippoboscids. We present the first description of the male of Icosta malagasii. An illustrated dichotomous determination key of the 14 Malagasy species, based on morphological criteria only, is presented. PMID:21678788

  11. GyrA ser83 and ParC trp106 Mutations in Salmonella enterica Serovar Typhi Isolated from Typhoid Fever Patients in Tertiary Care Hospital

    PubMed Central

    Gopal, Muthu; Elumalai, Sathishkumar; Arumugam, Suresh; Durairajpandian, Vishnuprabu; Kannan, Munirajan Arasambattu; Selvam, Esthermary

    2016-01-01

    Introduction Typhoid fever is endemic in India and other developing countries, causing major public health problems with high morbidity and mortality. The resistance of Salmonella enterica serovar Typhi (S. Typhi) towards commonly prescribed antimicrobials is increasing in developing countries. However, there have been several reports of the therapeutic failure of fluoroquinolones in patients with Salmonella infection. Resistance to quinolones/ fluoroquinolones commonly arises due to target site mutation. Aim The present study was planned to analyze mutation in Quinolone Resistance Determining Region (QRDR) of quinolone resistant Salmonella isolates. Materials and Methods A total of 133 S. Typhi isolates (blood (n = 131), stool (n=1) and bone marrow aspirate (n=1)) from tertiary care hospitals in Chennai and Puducherry, were included in this study. Minimum Inhibitory Concentrations (MIC) were carried out according to the Clinical Laboratory Standard Institute (CLSI)guidelines 2014. Mutations in gyrA and parC genes were analyzed by PCR-RFLP (Restriction Fragment Length Polymorphism) method followed by DNA sequencing. Results Of the 133 S. Typhi, 99.2% were resistant to nalidixic acid and 21% were resistant to ciprofloxacin by MIC method. 94% of isolates showed Ser 83 mutation in gyrA and 21.8% of isolates showed Trp106-Gly mutation in parC. Conclusion Mutations in gyrA and parC genes are highly prevalent among Salmonella species. Irrational use of fluoroquinolones may increase the accumulation of mutations in the DNA gyrase and topoisomerase encoding genes, which lead to the emergence of high level fluoroquinolone-resistant Salmonella strains in future.

  12. Maintenance and operation procedure, and feedback controls of the J-PARC RF-driven H{sup −} ion source

    SciTech Connect

    Ueno, A. Ohkoshi, K.; Ikegami, K.; Takagi, A.; Yamazaki, S.; Oguri, H.

    2015-04-08

    In order to satisfy the Japan Proton Accelerator Research Complex (J-PARC) second stage requirements of an H{sup −} ion beam of 60mA within normalized emittances of 1.5πmm•mrad both horizontally and vertically, a flat top beam duty factor of 1.25% (500μs×25Hz) and a life-time of longer than 1month, the J-PARC cesiated RF-driven H{sup −} ion source was developed by using an internal-antenna developed at the Spallation Neutron Source (SNS). The maintenance and operation procedure to minimize the plasma chamber (PCH) replacement time on the beam line, which is very important to maximize the J-PARC beam time especially for an antenna failure, is presented in this paper. The PCH preserved by filling argon (Ar) gas inside after pre-conditioning including pre-cesiation to produce the required beam at a test-stand successfully produced the required beam on the beam line with slight addition of cesium (Cs). The methods of the feedback controls of a 2MHz-RF-matching, an H{sup −} ion beam intensity and the addition of Cs are also presented. The RF-matching feedback by using two vacuum variable capacitors (VVCs) and RF-frequency shift produced the almost perfect matching with negligibly small reflected RF-power. The H{sup −} ion beam intensity was controlled within errors of ±0.1mA by the RF-power feedback. The amount of Cs was also controlled by remotely opening a Cs-valve to keep the RF-power lower than a settled value.

  13. Substitutions of Ser83Leu in GyrA and Ser80Leu in ParC Associated with Quinolone Resistance in Acinetobacter pittii.

    PubMed

    Gu, Dan-xia; Hu, Yun-jian; Zhou, Hong-wei; Zhang, Rong; Chen, Gong-xiang

    2015-06-01

    To investigate the prevalence and the mechanism of quinolone-resistant Acinetobacter pittii, 634 Acinetobacter calcoaceticus-Acinetobacter baumannii complex isolates were collected throughout Zhejiang Province. Identification of isolates was conducted by matrix-assisted laser desorption ionization/time of flight mass spectrometry (MALDI-TOF MS), blaOXA-51-like gene, and partial RNA polymerase β-subunit (rpoB) amplification. Twenty-seven isolates of A. pittii were identified. Among the 634 isolates, A. baumannii, A. pittii, Acinetobacter nosocomialis, and A. calcoaceticus counted for 87.22%, 4.26%, 8.20%, and 0.32%, respectively. Antimicrobial susceptibility of nalidixic acid, ofloxacin, enoxacin, ciprofloxacin, lomefloxacin, levofloxacin, sparfloxacin, moxifloxacin, and gatifloxacin for 27 A. pittii were determined by the agar dilution method. Detection of quinolone-resistant determining regions of gyrA, gyrB, parC, and parE was performed for the A. pittii isolates. In addition, plasmid-mediated quinolone resistance (PMQR) determinants (qnrA, qnrB, qnrS, qnrC, qnrD, aac(6')-Ib-cr, qepA, oqxA, and oqxB) were investigated. All the 27 isolates demonstrated a higher minimum inhibitory concentration (MIC) to old quinolones than the new fluoroquinolones. No mutation in gyrA, gyrB, parC, or parE was detected in 20 ciprofloxacin-susceptible isolates. Seven ciprofloxacin-resistant A. pittii were identified with a Ser83Leu mutation in GyrA. Among them, six isolates with simultaneous Ser83Leu amino acid substitution in GyrA and Ser80Leu in ParC displayed higher MIC values against ciprofloxacin. Additionally, three were identified with a Met370Ile substitution in ParE, and two were detected with a Tyr317His mutation in ParE, which were reported for the first time. No PMQR determinants were identified in the 27 A. pittii isolates. In conclusion, mutations in chromosome play a major role in quinolone resistance in A. pittii, while resistance mechanisms mediated by plasmid have

  14. Perfectly matched pulsed 2MHz RF network and CW 30MHz RF matching network for the J-PARC RF-driven H- ion source

    NASA Astrophysics Data System (ADS)

    Ueno, A.; Namekawa, Y.; Yamazaki, S.; Ohkoshi, K.; Koizumi, I.; Ikegami, K.; Takagi, A.; Oguri, H.

    2013-02-01

    In order to satisfy the Japan Proton Accelerator Research Complex (J-PARC) 2nd stage requirements of an H- ion beam current of 60mA within normalized emittances of 1.5πmmṡmrad both horizontally and vertically, a flat top beam duty factor of 1.25% (500μs×25Hz) and a life-time of more than 50days, a cesiated RF-driven H- ion source using a internal-antenna developed at the Spallation Neutron Source (SNS) was developed. As similar as the SNS ion source, the 60kW pulsed 2MHz-RF and 200W CW 30MHz-RF systems are used in order to produce pulsed high-temperature 2MHz-RF plasma and CW low-temperature 30MHz-RF plasma. Each matching network for each system is composed of two vacuum variable condensers (VVCs). In order to supply pulsed 60kW-2MHz-RF power from the power supply (PS) on the ground level, a one-turn isolation transformer using FINEMET cores is installed between the PS and the J-PARC ion source. By comprehending the matching networks with the LTspice IV simulations and high- and low- power experiments and setting the parameters properly, the pulsed 2MHz-RF power up to 46 kW is successfully input to the hydrogen plasma without any misfire and with almost no reflected power.

  15. Rare Kaon Decays, KEK experiment E391 and E14 at the Japan Physics and Accelerator Research Complex (J-PARC)

    SciTech Connect

    Wah, Yau Wai

    2012-12-06

    The goal of the J-PARC neutral kaon experiment (E14/KOTO) is to discover and measure the rate of the kaon rare decay to pi-zero and two neutrinos. This flavor changing neutral current decay proceeds through second-order weak interactions. Other, as yet undiscovered particles, which can mediate the decay could provide an enhancement (or depletion) to the branching ratio which in the Standard Model is accurately predicted within a few percent to be 2.8x10-11. The experiment is designed to observe more than 100 events at the Standard Model branching. It is a follow-up of the KEK E391a experiment and has stage-2 approval by J-PARC PAC in 2007. E14/KOTO has collaborators from Japan (Kyoto, Osaka, Yamagata, Saga), US (Arizona State, Chicago, Michigan Ann Arbor), Taiwan (National Taiwan), Korea, and Russia (Dubna). The experiment exploits the 300kW 30-50 GeV proton delivery of the J-PARC accelerator with a hermetic high acceptance detector with a fine grained Cesium Iodide (CsI) crystal calorimeter, and state of the art electronic front end and data acquisition system. With the recovery of the tsunami disaster on March 11th 2011, E14 is scheduled to start collecting data in December 2012. During the detector construction phase, Chicago focuses on the front end electronics readout of the entire detector system, particularly the CsI calorimeter. The CsI crystals together with its photomultipliers were previously used at the Fermilab KTeV experiment (E832/E799), and were loaned to E14 via this Chicago DOE support. The new readout electronics includes an innovative 10-pole pulse-shaping technique coupled with high speed digitization (14-bit 125MHz and 12-bit 500MHz). This new instrument enables us to measure both energy and timing, particularly with timing resolution better than 100 psec. Besides the cost saving by elimination of the standard time to digital converters, it is now possible to measure the momenta of the final state photons for additional background suppression

  16. Study of the elementary (K-, n) reactions to search for the K ¯NN bound state via the 3He (K-, n) reaction at J-PARC

    NASA Astrophysics Data System (ADS)

    Yamaga, Takumi; Ajimura, S.; Beer, G.; Berucci, C.; Bhang, H.; Bragadireanu, M.; Buehler, P.; Busso, L.; Cargnelli, M.; Choi, S.; Curceanu, C.; Enomoto, S.; Faso, D.; Fujioka, H.; Fujiwara, Y.; Fukuda, T.; Guaraldo, C.; Hashimoto, T.; Hayano, R. S.; Hiraiwa, T.; Iio, M.; Iliescu, M.; Inoue, K.; Ishiguro, Y.; Ishikawa, T.; Ishimoto, S.; Ishiwatari, T.; Itahashi, K.; Iwai, M.; Iwasaki, M.; Kanno, K.; Kato, K.; Kato, Y.; Kawasaki, S.; Kienle, P.; Kim, T.; Kou, H.; Ma, Y.; Marton, J.; Matsuda, Y.; Mizoi, Y.; Morra, O.; Nagae, T.; Noumi, H.; Ohnishi, H.; Okada, S.; Outa, H.; Piscicchia, K.; Vidal, A. Romero; Sada, Y.; Sakaguchi, A.; Sakuma, F.; Sato, M.; Scordo, A.; Sekimoto, M.; Shi, H.; Shirotori, K.; Sirghi, D.; Sirghi, F.; Suzuki, K.; Suzuki, S.; Suzuki, T.; Tanida, K.; Tatsuno, H.; Tokuda, M.; Tomono, D.; Toyoda, A.; Tsukada, K.; Doce, O. Vazquez; Widmann, E.; Wuenschek, B. K.; Yamazaki, T.; Yim, H.; Zhang, Q.; Zmeskal, J.

    2016-05-01

    We have searched for the simplest kaonic nuclear state, K ¯NN, using the in-flight 3He (K-, n) reaction at the J-PARC hadron experimental facility. In the semi-inclusive neutron missing-mass spectrum at θnla b=0° , an excess of yield was observed just below the K- pp mass-threshold, which cannot be explained by any elementary reactions [PTEP 2015, 061D01]. To understand the missing-mass spectrum of 3He (K-, n) X, we investigated the elementary (K-, n) reactions using hydrogen and deuterium targets. The p (K-, n) X missing-mass spectrum was well described by the charge-exchange reaction. However, in the d (K-, n) X spectrum, we observed an excess of yield just below the K- p mass-threshold, which was similar to that in the 3He (K-, n) X spectrum.

  17. Analysis of a rod withdrawal in a PWR core with the neutronic- thermalhydraulic coupled code RELAP/PARCS and RELAP/VALKIN

    SciTech Connect

    Miro, R.; Maggini, F.; Barrachina, T.; Verdu, G.; Gomez, A.; Ortego, A.; Murillo, J. C.

    2006-07-01

    The Reactor Ejection Accident (REA) belongs to the Reactor Initiated Accidents (RIA) category of accidents and it is part of the licensing basis accident analyses required for pressure water reactors (PWR). The REA at hot zero power (HZP) is characterized by a single rod ejection from a core position with a very low power level. The evolution consists basically of a continuous reactivity insertion. The main feature limiting the consequences of the accident in a PWR is the Doppler Effect. To check the performance of the coupled code RELAP5/PARCS2.5 and RELAP5/VALKIN a REA in Trillo NPP is simulated. These analyses will allow knowing more accurately the PWR real plant phenomenology in the RIA most limiting conditions. (authors)

  18. Development of a pulsed neutron three-dimensional imaging system using a highly sensitive image-intensifier at J-PARC

    NASA Astrophysics Data System (ADS)

    Segawa, M.; Ooi, M.; Kai, T.; Shinohara, T.; Kureta, M.; Sakamoto, K.; Imaki, T.

    2015-01-01

    To realize neutron energy resolved three-dimensional (3D) imaging in the resonance neutron energy region, a camera system coupled with a high sensitivity and high frame-rate gating image-intensifier was developed. The resonance absorption 3D imaging was successfully demonstrated at the pulsed neutron source of the Japan Proton Accelerator Research Complex (J-PARC). The camera system allowed us to obtain a time-of-flight (TOF) image of 2352 (W)×1726 (H) pixels resolved into a narrow energy range. 3D images with enhanced contrast at corresponding resonance energy regions for cylindrical Au, Ta, and In samples were reconstructed by convolution filtered back-projection (FBP) and maximum likelihood expectation maximization (MLEM) methods. The spatial resolution in the depth direction was evaluated experimentally to be approximately 1 mm. Our results show that the system could have applications in industrial fields.

  19. Fabrication of silica aerogel with n=1.08 for e+ /μ+ separation in a threshold Cherenkov counter of the J-PARC TREK/E36 experiment

    NASA Astrophysics Data System (ADS)

    Tabata, Makoto; Toyoda, Akihisa; Kawai, Hideyuki; Igarashi, Youichi; Imazato, Jun; Shimizu, Suguru; Yamazaki, Hirohito

    2015-09-01

    This study presents the development of hydrophobic silica aerogel for use as a radiator in threshold-type Cherenkov counters. These counters are to be used for separating positrons and positive muons produced by kaon decay in the J-PARC TREK/E36 experiment. We chose to employ aerogel with a refractive index of 1.08 to identify charged particles with momenta of approximately 240 MeV/c, and the radiator block shape was designed with a trapezoidal cross-section to fit the barrel region surrounding the kaon stopping target in the center of the TREK/E36 detector system. Including spares, we obtained 30 crack-free aerogel blocks segmented into two layers, each layer having a thickness of 2 cm and a length of 18 cm, to fill 12 counter modules. Optical measurements showed that the produced aerogel tiles had the required refractive indices and transparency.

  20. Are low altitude alpine tundra ecosystems under threat? A case study from the Parc National de la Gaspésie, Québec

    NASA Astrophysics Data System (ADS)

    Dumais, Catherine; Ropars, Pascale; Denis, Marie-Pier; Dufour-Tremblay, Geneviève; Boudreau, Stéphane

    2014-09-01

    According to the 2007 IPCC report, the alpine tundra ecosystems found on low mountains of the northern hemisphere are amongst the most threatened by climate change. A treeline advance or a significant erect shrub expansion could result in increased competition for the arctic-alpine species usually found on mountaintops and eventually lead to their local extinction. The objectives of our study were to identify recent changes in the cover and growth of erect woody vegetation in the alpine tundra of Mont de la Passe, in the Parc National de la Gaspésie (Québec, Canada). The comparison of two orthorectified aerial photos revealed no significant shift of the treeline between 1975 and 2004. During the same period however, shrub species cover increased from 20.2% to 30.4% in the lower alpine zone. Dendrochronological analyses conducted on Betula glandulosa Michx. sampled at three different positions along an altitudinal gradient (low, intermediate and high alpine zone) revealed that the climatic determinants of B. glandulosa radial growth become more complex with increasing altitude. In the lower alpine zone, B. glandulosa radial growth is only significantly associated positively to July temperature. In the intermediate alpine zone, radial growth is associated positively to July temperature but negatively to March temperature. In the high alpine zone, radial growth is positively associated to January, July and August temperature but negatively to March temperature. The positive association between summer temperatures and radial growth suggests that B. glandulosa could potentially benefit from warmer temperatures, a phenomenon that could lead to an increase in its cover over the next few decades. Although alpine tundra vegetation is not threatened in the short-term in the Parc National de la Gaspésie, erect shrub cover, especially B. glandulosa, could likely increase in the near future, threatening the local arctic-alpine flora.

  1. In Vitro Activity of Five Quinolones and Analysis of the Quinolone Resistance-Determining Regions of gyrA, gyrB, parC, and parE in Ureaplasma parvum and Ureaplasma urealyticum Clinical Isolates from Perinatal Patients in Japan

    PubMed Central

    Kawai, Yasuhiro; Nakura, Yukiko; Wakimoto, Tetsu; Nomiyama, Makoto; Tokuda, Tsugumichi; Takayanagi, Toshimitsu; Shiraishi, Jun; Wasada, Kenshi; Kitajima, Hiroyuki; Fujita, Tomio; Nakayama, Masahiro; Mitsuda, Nobuaki; Nakanishi, Isao; Takeuchi, Makoto

    2015-01-01

    Ureaplasma spp. cause several disorders, such as nongonococcal urethritis, miscarriage, and preterm delivery with lung infections in neonates, characterized by pathological chorioamnionitis in the placenta. Although reports on antibiotic resistance in Ureaplasma are on the rise, reports on quinolone-resistant Ureaplasma infections in Japan are limited. The purpose of this study was to determine susceptibilities to five quinolones of Ureaplasma urealyticum and Ureaplasma parvum isolated from perinatal samples in Japan and to characterize the quinolone resistance-determining regions in the gyrA, gyrB, parC, and parE genes. Out of 28 clinical Ureaplasma strains, we isolated 9 with high MICs of quinolones and found a single parC gene mutation, resulting in the change S83L. Among 158 samples, the ParC S83L mutation was found in 37 samples (23.4%), including 1 sample harboring a ParC S83L–GyrB P462S double mutant. Novel mutations of ureaplasmal ParC (S83W and S84P) were independently found in one of the samples. Homology modeling of the ParC S83W mutant suggested steric hindrance of the quinolone-binding pocket (QBP), and de novo prediction of peptide structures revealed that the ParC S84P may break/kink the formation of the α4 helix in the QBP. Further investigations are required to unravel the extent and mechanism of antibiotic resistance of Ureaplasma spp. in Japan. PMID:25645833

  2. Physics potential of a long-baseline neutrino oscillation experiment using a J-PARC neutrino beam and Hyper-Kamiokande

    NASA Astrophysics Data System (ADS)

    Abe, K.; Aihara, H.; Andreopoulos, C.; Anghel, I.; Ariga, A.; Ariga, T.; Asfandiyarov, R.; Askins, M.; Back, J. J.; Ballett, P.; Barbi, M.; Barker, G. J.; Barr, G.; Bay, F.; Beltrame, P.; Berardi, V.; Bergevin, M.; Berkman, S.; Berry, T.; Bhadra, S.; Blaszczyk, F. d. M.; Blondel, A.; Bolognesi, S.; Boyd, S. B.; Bravar, A.; Bronner, C.; Cafagna, F. S.; Carminati, G.; Cartwright, S. L.; Catanesi, M. G.; Choi, K.; Choi, J. H.; Collazuol, G.; Cowan, G.; Cremonesi, L.; Davies, G.; De Rosa, G.; Densham, C.; Detwiler, J.; Dewhurst, D.; Di Lodovico, F.; Di Luise, S.; Drapier, O.; Emery, S.; Ereditato, A.; Fernández, P.; Feusels, T.; Finch, A.; Fitton, M.; Friend, M.; Fujii, Y.; Fukuda, Y.; Fukuda, D.; Galymov, V.; Ganezer, K.; Gonin, M.; Gumplinger, P.; Hadley, D. R.; Haegel, L.; Haesler, A.; Haga, Y.; Hartfiel, B.; Hartz, M.; Hayato, Y.; Hierholzer, M.; Hill, J.; Himmel, A.; Hirota, S.; Horiuchi, S.; Huang, K.; Ichikawa, A. K.; Iijima, T.; Ikeda, M.; Imber, J.; Inoue, K.; Insler, J.; Intonti, R. A.; Irvine, T.; Ishida, T.; Ishino, H.; Ishitsuka, M.; Itow, Y.; Izmaylov, A.; Jamieson, B.; Jang, H. I.; Jiang, M.; Joo, K. K.; Jung, C. K.; Kaboth, A.; Kajita, T.; Kameda, J.; Karadhzov, Y.; Katori, T.; Kearns, E.; Khabibullin, M.; Khotjantsev, A.; Kim, J. Y.; Kim, S. B.; Kishimoto, Y.; Kobayashi, T.; Koga, M.; Konaka, A.; Kormos, L. L.; Korzenev, A.; Koshio, Y.; Kropp, W. R.; Kudenko, Y.; Kutter, T.; Kuze, M.; Labarga, L.; Lagoda, J.; Laveder, M.; Lawe, M.; Learned, J. G.; Lim, I. T.; Lindner, T.; Longhin, A.; Ludovici, L.; Ma, W.; Magaletti, L.; Mahn, K.; Malek, M.; Mariani, C.; Marti, L.; Martin, J. F.; Martin, C.; Martins, P. P. J.; Mazzucato, E.; McCauley, N.; McFarland, K. S.; McGrew, C.; Mezzetto, M.; Minakata, H.; Minamino, A.; Mine, S.; Mineev, O.; Miura, M.; Monroe, J.; Mori, T.; Moriyama, S.; Mueller, T.; Muheim, F.; Nakahata, M.; Nakamura, K.; Nakaya, T.; Nakayama, S.; Needham, M.; Nicholls, T.; Nirkko, M.; Nishimura, Y.; Noah, E.; Nowak, J.; Nunokawa, H.; O'Keeffe, H. M.; Okajima, Y.; Okumura, K.; Oser, S. M.; O'Sullivan, E.; Ovsiannikova, T.; Owen, R. A.; Oyama, Y.; Pérez, J.; Pac, M. Y.; Palladino, V.; Palomino, J. L.; Paolone, V.; Payne, D.; Perevozchikov, O.; Perkin, J. D.; Pistillo, C.; Playfer, S.; Posiadala-Zezula, M.; Poutissou, J.-M.; Quilain, B.; Quinto, M.; Radicioni, E.; Ratoff, P. N.; Ravonel, M.; Rayner, M. A.; Redij, A.; Retiere, F.; Riccio, C.; Richard, E.; Rondio, E.; Rose, H. J.; Ross-Lonergan, M.; Rott, C.; Rountree, S. D.; Rubbia, A.; Sacco, R.; Sakuda, M.; Sanchez, M. C.; Scantamburlo, E.; Scholberg, K.; Scott, M.; Seiya, Y.; Sekiguchi, T.; Sekiya, H.; Shaikhiev, A.; Shimizu, I.; Shiozawa, M.; Short, S.; Sinnis, G.; Smy, M. B.; Sobczyk, J.; Sobel, H. W.; Stewart, T.; Stone, J. L.; Suda, Y.; Suzuki, Y.; Suzuki, A. T.; Svoboda, R.; Tacik, R.; Takeda, A.; Taketa, A.; Takeuchi, Y.; Tanaka, H. A.; Tanaka, H. K. M.; Tanaka, H.; Terri, R.; Thompson, L. F.; Thorpe, M.; Tobayama, S.; Tolich, N.; Tomura, T.; Touramanis, C.; Tsukamoto, T.; Tzanov, M.; Uchida, Y.; Vagins, M. R.; Vasseur, G.; Vogelaar, R. B.; Walter, C. W.; Wark, D.; Wascko, M. O.; Weber, A.; Wendell, R.; Wilkes, R. J.; Wilking, M. J.; Wilson, J. R.; Xin, T.; Yamamoto, K.; Yanagisawa, C.; Yano, T.; Yen, S.; Yershov, N.; Yokoyama, M.; Zito, M.

    2015-05-01

    Hyper-Kamiokande will be a next-generation underground water Cherenkov detector with a total (fiducial) mass of 0.99 (0.56) million metric tons, approximately 20 (25) times larger than that of Super-Kamiokande. One of the main goals of Hyper-Kamiokande is the study of CP asymmetry in the lepton sector using accelerator neutrino and anti-neutrino beams. In this paper, the physics potential of a long-baseline neutrino experiment using the Hyper-Kamiokande detector and a neutrino beam from the J-PARC proton synchrotron is presented. The analysis uses the framework and systematic uncertainties derived from the ongoing T2K experiment. With a total exposure of 7.5 MW × 10^7s integrated proton beam power (corresponding to 1.56 × 10^{22} protons on target with a 30 GeV proton beam) to a 2.5^circ off-axis neutrino beam, it is expected that the leptonic CP phase δ _{CP} can be determined to better than 19 degrees for all possible values of δ _{CP}, and CP violation can be established with a statistical significance of more than 3 σ (5 σ) for 76{%} (58{%}) of the {δ _{CP}} parameter space. Using both ν _e appearance and ν _μ disappearance data, the expected 1σ uncertainty of sin ^2θ _{23} is 0.015(0.006) for sin ^2θ _{23}=0.5(0.45).

  3. Design of Injection and Extraction at an 8-GeV Booster Ring and the J-PARC Main Ring for Multi-MW Output Beam Power

    NASA Astrophysics Data System (ADS)

    Harada, Hiroyuki; Hotchi, Hideaki; Igarashi, Susumu; Sato, Yoichi; Koseki, Tadashi

    The 240-kW output beam power in the MR has been achieved for a 30-GeV user operation with the repetition cycle of 2.48 sec and injecting proton beams of 380-kW equivalent intensity from RCS. The MR aims to realize 750-kW beam operation with faster repetition cycle of ˜1 s and injecting proton beams of 600-kW equivalent intensity from RCS. The MR is developing the new type power supplies of MR main magnets and high-impedance core of MR RF cavities toward faster repetition cycle. We are now exploring the further beam power upgrade scenario of the J-PARC accelerators. As one possible scenario toward a multi-MW output beam power from MR, a new 8-GeV booster ring (BR) between RCS and MR is also designed. The injection energy of the MR increases from present 3-GeV to 8-GeV. The higher injection energy of the MR would be able to mitigate a space charge force in MR injection energy region and secure the acceptance clearance of beam from MR physical aperture. In this paper, the designed injection and extraction system of BR are described. Additionally, a new concept of BR extraction and MR injection toward multi-MW output beam power are described.

  4. Measurement of the Strong Interaction Induced Shift and Width of the 1s State of Kaonic Deuterium at J-PARC

    NASA Astrophysics Data System (ADS)

    Zmeskal, J.; Sato, M.; Ajimura, S.; Bazzi, M.; Beer, G.; Berucci, C.; Bhang, H.; Bosnar, D.; Bragadireanu, M.; Buehler, P.; Busso, L.; Cargnelli, M.; Choi, S.; Clozza, A.; Curceanu, C.; D'Uffizi, A.; Enomoto, S.; Fabbietti, L.; Faso, D.; Fiorini, C.; Fujioka, H.; Ghio, F.; Golser, R.; Guaraldo, C.; Hashimoto, T.; Hayano, R. S.; Hiraiwa, T.; Iio, M.; Iliescu, M.; Inoue, K.; Ishimoto, S.; Ishiwatari, T.; Itahashi, K.; Iwai, M.; Iwasaki, M.; Kawasaki, S.; Lachner, J.; Levi Sandri, P.; Ma, Y.; Marton, J.; Matsuda, Y.; Mizoi, Y.; Morra, O.; Moskal, P.; Nagae, T.; Noumi, H.; Ohnishi, H.; Okada, S.; Outa, H.; Pietreanu, D.; Piscicchia, K.; Poli Lener, M.; Romero Vidal, A.; Sada, Y.; Sakaguchi, A.; Sakuma, F.; Sbardella, E.; Scordo, A.; Sekimoto, M.; Shi, H.; Silarski, M.; Sirghi, D.; Sirghi, F.; Suzuki, K.; Suzuki, S.; Suzuki, T.; Tanida, K.; Tatsuno, H.; Tokuda, M.; Toyoda, A.; Tucakovic, I.; Tsukada, K.; Vazquez Doce, O.; Widmann, E.; Yamaga, T.; Yamazaki, T.; Zhang, Q.

    The antikaon-nucleon interaction close to threshold provides crucial information on the interplay between spontaneous and explicit chiral symmetry breaking in low-energy QCD. In this context the importance of kaonic deuterium X-ray spectroscopy has been well recognized, but no experimental results have yet been obtained due to the difficulty of the measurement. We propose to measure the shift and width of the kaonic deuterium 1s state with an accuracy of 60 eV and 140 eV respectively at J-PARC. These results together with the kaonic hydrogen data (KpX at KEK, DEAR and SIDDHARTA at DAFNE) will then permit the determination of values of both the isospin I=0 and I=1 antikaon-nucleon scattering lengths and will provide the most stringent constraints on the antikaon-nucleon interaction, promising a breakthrough. Refined Monte Carlo studies were performed, including the investigation of background suppression factors for the described setup. These studies have demonstrated the feasibility of determining the shift and width of the kaonic deuterium atom 1s state with the desired accuracy of 60 eV and 140 eV.

  5. Numerical study for beam loss occurring for wide-ranging transverse injection painting and its mitigation scenario in the J-PARC 3-GeV RCS

    NASA Astrophysics Data System (ADS)

    Hotchi, Hideaki; Tani, Norio; Watanabe, Yasuhiro

    2015-04-01

    In the J-PARC 3-GeV Rapid Cycling Synchrotron (RCS), transverse injection painting is utilized to manipulate the transverse beam profile according to the requirements from the downstream facilities as well as to mitigate the space-charge induced beam loss in RCS. Therefore, a flexible control is required for the transverse painting area. But now the available range of transverse painting is limited to small area due to beta function beating caused by the edge focus of injection bump magnets which operate during the beam injection period. This beta function beating additionally excites various random betatron resonances through a distortion of the lattice super-periodicity, causing a shrinkage of the dynamic aperture during the injection period. This decrease of the dynamic aperture leads to extra beam loss at present when applying large transverse painting. For beta function beating caused by the edge focus, we proposed a correction scheme with additional pulse-type quadrupole correctors. In this paper, we will discuss the feasibility and effectiveness of this correction scheme for expanding the transverse injection painting area with no extra beam loss, while considering the beam loss and its mitigation mechanisms, based on numerical simulations.

  6. Enseigner les termes techniques en francais

    ERIC Educational Resources Information Center

    Charbonneau, Yvon

    1974-01-01

    The author notes that most business and economic terms are in English; this, he writes, is unfortunate for the future of the French language. He gives nine ways to teach a technical vocabulary. (The article is in French.) (JA)

  7. Le Francais Courant, I (Contemporary French, I).

    ERIC Educational Resources Information Center

    Dade County Public Schools, Miami, FL.

    Performance objectives focusing on the development of introductory skills in comprehension, speaking, reading, and writing are presented in this text of instructional materials. Lessons center about the use of short dialogues based on everyday, teenage experiences. Special emphasis is placed on vocabulary expansion, present tense of selected…

  8. Le Francais Courant (Contemporary French), Part II.

    ERIC Educational Resources Information Center

    Dade County Public Schools, Miami, FL.

    This course has been developed basically within the limits of Units 4-6 of "A-LM French: Level 1", second edition. The primary objectives are to develop French vocabulary relative to the family, home, transportation, and foods by continuing to work with short dialogues based on everyday, teenage experiences. While reviewing previously studied…

  9. Le Francais Moderne, (Modern French) Part II.

    ERIC Educational Resources Information Center

    Dade County Public Schools, Miami, FL.

    Performance objectives and broad goals for listening, speaking, reading, and writing skills in French instruction are presented in this text. Cultural awareness and student attitude are also considered. Vocabulary and structure of the course are presented through three situations: shopping, meeting a train, and making vacation plans. Short films…

  10. Le Francais quand meme (French Nonetheless).

    ERIC Educational Resources Information Center

    Delautier, Jean-Marie

    1983-01-01

    Political, attitudinal, and administrative problems of teaching compulsory foreign languages in Colombia are described and discussed from the point of view of a French teacher in a system characterized by confusion and lack of student interest. (MSE)

  11. Etude Differentielle Intonative Francais/Anglais.

    ERIC Educational Resources Information Center

    Lepetit, D.; Martin, Ph.

    1990-01-01

    Describes an investigation of the differences and similarities existing between the intonation systems of French and English. The unity of the procedures described here is confirmed by an analysis of intonational errors made by English-speaking learners of French. (Author/VWL)

  12. Dependence of beam emittance on plasma electrode temperature and rf-power, and filter-field tuning with center-gapped rod-filter magnets in J-PARC rf-driven H- ion source

    NASA Astrophysics Data System (ADS)

    Ueno, A.; Koizumi, I.; Ohkoshi, K.; Ikegami, K.; Takagi, A.; Yamazaki, S.; Oguri, H.

    2014-02-01

    The prototype rf-driven H- ion-source with a nickel plated oxygen-free-copper (OFC) plasma chamber, which satisfies the Japan Proton Accelerator Research Complex (J-PARC) 2nd stage requirements of a H- ion beam current of 60 mA within normalized emittances of 1.5 π mm mrad both horizontally and vertically, a flat top beam duty factor of 1.25% (500 μs × 25 Hz) and a life-time of more than 50 days, was reported at the 3rd international symposium on negative ions, beams, and sources (NIBS2012). The experimental results of the J-PARC ion source with a plasma chamber made of stainless-steel, instead of nickel plated OFC used in the prototype source, are presented in this paper. By comparing these two sources, the following two important results were acquired. One was that the about 20% lower emittance was produced by the rather low plasma electrode (PE) temperature (TPE) of about 120 °C compared with the typically used TPE of about 200 °C to maximize the beam current for the plasma with the abundant cesium (Cs). The other was that by using the rod-filter magnets with a gap at each center and tuning the gap-lengths, the filter-field was optimized and the rf-power necessary to produce the J-PARC required H- ion beam current was reduced typically 18%. The lower rf-power also decreases the emittances.

  13. Dependence of beam emittance on plasma electrode temperature and rf-power, and filter-field tuning with center-gapped rod-filter magnets in J-PARC rf-driven H{sup −} ion source

    SciTech Connect

    Ueno, A. Koizumi, I.; Ohkoshi, K.; Ikegami, K.; Takagi, A.; Yamazaki, S.; Oguri, H.

    2014-02-15

    The prototype rf-driven H{sup −} ion-source with a nickel plated oxygen-free-copper (OFC) plasma chamber, which satisfies the Japan Proton Accelerator Research Complex (J-PARC) 2nd stage requirements of a H{sup −} ion beam current of 60 mA within normalized emittances of 1.5 π mm mrad both horizontally and vertically, a flat top beam duty factor of 1.25% (500 μs × 25 Hz) and a life-time of more than 50 days, was reported at the 3rd international symposium on negative ions, beams, and sources (NIBS2012). The experimental results of the J-PARC ion source with a plasma chamber made of stainless-steel, instead of nickel plated OFC used in the prototype source, are presented in this paper. By comparing these two sources, the following two important results were acquired. One was that the about 20% lower emittance was produced by the rather low plasma electrode (PE) temperature (T{sub PE}) of about 120 °C compared with the typically used T{sub PE} of about 200 °C to maximize the beam current for the plasma with the abundant cesium (Cs). The other was that by using the rod-filter magnets with a gap at each center and tuning the gap-lengths, the filter-field was optimized and the rf-power necessary to produce the J-PARC required H{sup −} ion beam current was reduced typically 18%. The lower rf-power also decreases the emittances.

  14. Development of a prototype GEM TPC with a gating grid for an H-dibaryon search experiment at J-PARC

    NASA Astrophysics Data System (ADS)

    Sako, H.; Sugimura, H.; Ahn, J. K.; Han, Y.; Hasegawa, S.; Hwang, S. H.; Ichikawa, Y.; Imai, K.; Kiuchi, R.; Ozawa, K.; Sato, S.; Shirotori, K.

    2014-11-01

    We have developed a prototype TPC (Time Projection Chamber) based on GEMs (Gas Electron Multipliers) with a gating grid for an H-dibaryon search experiment at J-PARC. To investigate its performance, we conducted laboratory tests and a beam test with two kinds of gases, Ar-CH4 (90:10) and Ar-CF4 (95:5), where the former is mainly used for the tests. The hit detection efficiency per pad row was measured to be 98% at the beam rate up to 5×105 cps cm2 (counts per second), and 90% at the rate of 3×106 cps/cm2. Based on the measured horizontal resolution of 0.19-0.46 mm at the drift length of 5-20 cm, the horizontal position resolution of better than 0.3 mm is estimated in 1 T magnetic field for the final experiment. The ion backflow fraction was measured to be 5% and reduced up to 3% by tuning the GEM voltage configuration, at the gain of 1.6 ×104. The horizontal position distortion due to ion backflow in the gate operation was suppressed within 0.2 mm at the beam rates up to 5 ×105 cps /cm2, corresponding to the ion backflow up to 2.7 ×108s-1cm-1. On the other hand, the distortion with the gate open was measured to be 1.3 mm, corresponding to the backflow of 1.3 ×109s-1cm-1. The distortion in the final experiment is estimated to be 0.3 ± 0.2 mm, within the requirement of 1 mm. The GEMs have been operated continuously for a comparable period of the final experiment, with average energy deposit rates per unit GEM area of 30 times as high as that expected for the experiment.

  15. First 2 years of Atmospheric CO2 measurements in the Estany Llong plain (2100 masl, Parc Nacional d'Aigüestortes i Estany de Sant Maurici, Pyrenees, Catalonia, Spain).

    NASA Astrophysics Data System (ADS)

    Curcoll, Roger; Recolons, Montserrat; Font, Anna; Agraz, Laura; Parga, Elena; Bacardit, Montse; Camarero, Lluís.; Pueyo, Salva; Rodó, Xavier; Morguí, Josep Anton

    2010-05-01

    Since April 2009, air samples are being taken bi-weekly at 10 GMT in the plain of the Estany Llong at 2100 masl. Estany Llong air sampling site (ELL, 42°34'29''N 0°57'17''E) is a remote site situated in the SW principal valley of the Parc Nacional d'Aigüestortes i Estany de Sant Maurici. New Flask-sampling equipment for Remote Mountain Sites was developed by the Institut Català de Ciències del Clima (IC3) to allow flask sampling in extreme weather conditions and carrying the sampling equipment for more than 10 km without damaging flasks. Dry Air analysis for CO2 are done at the Laboratory of IC3 using two coupled modified IRGA Licor-7000, where both pressure and flow are externally controlled. Far away from populated areas, ELL site acts as a remote site, but it is also responding to discrete events as snow melting, summer cattle breeding on pastures and trekking frequentation. Series of CO2 obtained are included as part of Long Term Ecological Research (LTER) at the Parc Nacional d'Aigüestortes i Estany de Sant Maurici. In the long term, these measurements show the mountain ecosystems contribution and geomorphologic influence on the CO2 budget of the air masses crossing a mountain range.

  16. Pourquoi le francais et quel francais au Maroc? (Why French and Which French in Morocco?)

    ERIC Educational Resources Information Center

    Akouaou, Ahmed

    1984-01-01

    The status of French in Morocco is ambiguous: it is neither an official language nor a foreign language, and it would benefit greatly from an official definition that would allow a variety of language conflicts to be resolved. (MSE)

  17. Overexpression of an ABC transporter and mutations of GyrA, GyrB, and ParC in contributing to high-level ciprofloxacin resistance in Streptococcus suis type 2.

    PubMed

    Yao, Jie; Shang, Kexin; Huang, Jinhu; Ran, Wei; Kashif, Jam; Wang, Liping

    2014-04-01

    Streptococcus suis is a pathogen of zoonotic diseases. Moreover, the emergence of fluoro-quinolones (FQs) resistance in this pathogen has severe consequences for pigs and human health. In this study, the molecular mechanism of FQs resistance in S. suis type 2 (SS2) sensitive strains isolated from pigs was assessed after in vitro induction of resistance against the most frequently used FQs: ciprofloxacin, norfloxacin, and enrofloxacin. Proteome analysis, sequencing and real-time RT-PCR results strongly established an overexpression of an ABC transporter protein (other than SatAB) and topoisomerase mutations in GyrA (Ser81Arg), GyrB (Glu354Lys), and ParC (Ser79Phe) in contributing to high level ciprofloxacin resistance in SS2. Due to the overexpression of the ABC transporter, intracellular ciprofloxacin concentrations were significantly lower in the resistant strains than those of sensitive strains after 20, 35, and 60 min exposures to ciprofloxacin (p < 0.05). It was concluded that improper use of FQs is one of the main causes of the emergence of this zoonotic pathogen as a multiresistant organism against commonly used antibiotics. The existence of an efflux-like protein is an incentive to find new drug targets to avoid the spread of FQs-resistant S. suis isolates in pigs and the human population. PMID:24815385

  18. Electrogenic NBCe1 (SLC4A4), but not electroneutral NBCn1 (SLC4A7), cotransporter undergoes cholinergic-stimulated endocytosis in salivary ParC5 cells

    PubMed Central

    Perry, Clint; Quissell, David O.; Reyland, Mary E.; Grichtchenko, Irina I.

    2008-01-01

    Cholinergic agonists are major stimuli for fluid secretion in parotid acinar cells. Saliva bicarbonate is essential for maintaining oral health. Electrogenic and electroneutral Na+-HCO3− cotransporters (NBCe1 and NBCn1) are abundant in parotid glands. We previously reported that angiotensin regulates NBCe1 by endocytosis in Xenopus oocytes. Here, we studied cholinergic regulation of NBCe1 and NBCn1 membrane trafficking by confocal fluorescent microscopy and surface biotinylation in parotid epithelial cells. NBCe1 and NBCn1 colocalized with E-cadherin monoclonal antibody at the basolateral membrane (BLM) in polarized ParC5 cells. Inhibition of constitutive recycling with the carboxylic ionophore monensin or the calmodulin antagonist W-13 caused NBCe1 to accumulate in early endosomes with a parallel loss from the BLM, suggesting that NBCe1 is constitutively endocytosed. Carbachol and PMA likewise caused redistribution of NBCe1 from BLM to early endosomes. The PKC inhibitor, GF-109203X, blocked this redistribution, indicating a role for PKC. In contrast, BLM NBCn1 was not downregulated in parotid acinar cells treated with constitutive recycling inhibitors, cholinergic stimulators, or PMA. We likewise demonstrate striking differences in regulation of membrane trafficking of NBCe1 vs. NBCn1 in resting and stimulated cells. We speculate that endocytosis of NBCe1, which coincides with the transition to a steady-state phase of stimulated fluid secretion, could be a part of acinar cell adjustment to a continuous secretory response. Stable association of NBCn1 at the membrane may facilitate constitutive uptake of HCO3− across the BLM, thus supporting HCO3− luminal secretion and/or maintaining acid-base homeostasis in stimulated cells. PMID:18815229

  19. French: An Accommodating Language? = Le Francais: Langue D'Accueil?

    ERIC Educational Resources Information Center

    Wright, Sue, Ed.

    This bilingual book considers recent developments in French attitudes towards language purism, borrowing, and the incursion of English. The book begins with an essay by French sociolinguist Henriette Walter, and most of the following essays are direct responses to her ideas. All chapters are provided in French and English. Chapter titles include…

  20. Morphologie et syntaxe du francais (French Morphology and Syntax)

    ERIC Educational Resources Information Center

    Sourdot, Marc

    1977-01-01

    A study of the relationship of morphology and syntax to the communication process from the functionalist viewpoint. Topics considered are: morphological processes, that is the distinction between functional and contingent language facts; the degree of necessity of syntax; the difference between functionalism and traditional grammar. (Text is in…

  1. Parier sur le francais fonctionnel (Betting on Functional French).

    ERIC Educational Resources Information Center

    Larramendy, Jean-Louis

    1990-01-01

    A discussion of second-language learning looks at the role of functional French in the acquisition of French as a second or foreign language. The choice and implementation of a Vygotskian approach using the study of electricity is described. (MSE)

  2. Un cours avance de francais: Le francais tel qu'on le parle (An Advanced Course in French: Colloquial French)

    ERIC Educational Resources Information Center

    Creusot, Andre

    1971-01-01

    Second of three articles on an advanced French program sponsored by the Language Department of the State University of Mons, Belgium. Emphasis is on the phonology, lexicology, and syntax of spoken French. (DS)

  3. PARC, Lau, Rodriguez, and Individualized Education.

    ERIC Educational Resources Information Center

    Gilhool, Tom

    1978-01-01

    The values of individualized education have in recent years taken on new strength. The cases and the statutes which have contributed to that increasing strength suggest that it may be possible to realize these values within the public school system itself. (Author/EB)

  4. Une Planche de Salut pour le Francais: le Francais Quotidien et les Niveaux de Langue (A Last Resort for French: Everyday French and Language Levels)

    ERIC Educational Resources Information Center

    Jonas, Maurice

    1977-01-01

    Before asking how to teach French, one should ask what French to teach. It is suggested that everyday French, "la langue usuelle," should be the norm for American teachers and textbook writers and editers. Greater utilization of film scenarios and songs of good quality are among the means suggested. (Text is in French.) (AMH)

  5. Modeles de rendement langagier: Francais, 12e annee. Francais langue premiere (Models of Linguistic Production: French, 12th Grade. French as a Native Language).

    ERIC Educational Resources Information Center

    Alberta Learning, Edmonton. Direction de l'education francaise.

    Aligned with its 1998 standards for first- and second-language learning, Alberta Learning has published lesson plans that aim for a closer relationship between learning and evaluation. Each volume in this series presents a specific task for students that involves planning, carrying out, and evaluating their work. The task for twelfth grade…

  6. Uruguay: Le francais en quete d'image (Uruguay: French in Search of an Image).

    ERIC Educational Resources Information Center

    Francais dans le Monde, 1993

    1993-01-01

    The role of French language instruction in Uruguay is assessed. Drawing on results of recent surveys, it is observed that French suffers from a lackluster image, and from a lack of confidence among language teachers themselves. (MSE)

  7. Le Gateway, un cours de francais intensif experimental (Gateway, An Experimental Intensive French Language Course).

    ERIC Educational Resources Information Center

    Landes, Anne N.; Audigier, Jean

    1995-01-01

    An intensive college-level French language course, based on the principles of immersion and designed to aid students in the transition between intermediate and advanced proficiency levels, is described. Focus is on three course aspects: teacher contacts; meetings with native-speaking students; and use of audiovisual aids. (21 references) (MSE)

  8. Une Nouvelle Place pour le francais au Senegal? (A New Place for French in Senegal?)

    ERIC Educational Resources Information Center

    Ka, Omar

    1993-01-01

    A discussion of the role of the French language in Senegal first chronicles language and education policy from the colonial period until 1980, then cites research indicating that French is infrequently used for personal purposes. Recent initiatives to strengthen its status and usage, and obstacles to their success, are outlined. (MSE)

  9. Aspirations langagieres: Negociation et apprentissage du francais (Language Aspirations: Negotiation and Learning French).

    ERIC Educational Resources Information Center

    Lepetit, Daniel; Cichocki, Wladyslaw

    1990-01-01

    A survey of 130 beginning French students at the University of Windsor (Canada) focused on their second language aspirations, expectations, and anticipated needs. Interpersonal relations appear to be the primary motivator, with travel and instrumental motivation secondary. (20 references) (Author/MSE)

  10. Un trait du francais parle authentique: La dislocation. (A Trait of Authentic Spoken French: Dislocation.)

    ERIC Educational Resources Information Center

    Calve, Pierre

    1983-01-01

    The dislocation of sentence elements in spoken French is seen as allowing the speaker to free himself from certain constraints imposed on word order, position of accents, and grammar. Dislocation is described, its various functions are enumerated, and implications for second language instruction are outlined. (MSE)

  11. Technoscientific French Teaching Guide = Guide pour l'enseignement du Francais technoscientifique.

    ERIC Educational Resources Information Center

    Muller, Brigitte D.

    This course guide aids university professors in doing research to develop a course in scientific and technical French. The course is intended to aid students in developing communicative skills in French in the context of science and technology. The course introduces students to the culture of France as well as to its industrial and technological…

  12. Lexique anglais-francais du microfilm (Glossary of English-French Microfilm Terminology)

    ERIC Educational Resources Information Center

    Pollett, Ray

    1974-01-01

    Presents a list of English-French equivalents for terminology dealing with microfilm. Most of the terms listed were taken from technical documents and brochures of the Kodak Company. (Text is in French.) (PP)

  13. Curriculum de francais: Elaboration, experimentation et evaluation (French Curriculum: Elaboration, Experimentation, and Evaluation).

    ERIC Educational Resources Information Center

    Groux, Dominique

    1991-01-01

    A cooperative project to improve the French second-language curriculum in Egyptian schools is described, including the challenges and principles involved in designing a 13-year elementary-secondary curriculum, pilot testing in 2 schools, teacher workshops, networking among participants, results, and lessons learned. (MSE)

  14. Le Francais parle. Etudes sociolinguistiques (Spoken French. Sociolinguistic Studies). Current Inquiry into Languages and Linguistics 30.

    ERIC Educational Resources Information Center

    Thibault, Pierrette

    This volume contains twelve articles dealing with the French language as spoken in Quebec. The following topics are addressed: (1) language change and variation; (2) coordinating expressions in the French spoken in Montreal; (3) expressive language as source of language change; (4) the role of correction in conversation; (5) social change and…

  15. Le francais fonde sur la competence, Novice (Competency Based French, Novice).

    ERIC Educational Resources Information Center

    Dimanche, Maurice

    This instructional guide in French is intended for training Peace Corps volunteers serving in the Central African Republic. The guide includes 21 topical lessons at the introductory level, each consisting of briefly stated competency objectives and a number of brief, related situational dialogues. Lesson topics include: greetings; introducing…

  16. Le francais fonde sur la competence, Intermediare (Competency Based French, Intermediate).

    ERIC Educational Resources Information Center

    Dimanche, Maurice

    This instructional guide in French is intended for training Peace Corps volunteers serving in the Central African Republic. It includes 35 topical lessons at the intermediate level, each consisting of briefly stated competency objectives and a number of brief, related situational dialogues. Lesson topics include: introducing oneself; introducing…

  17. Une lecon de francais avec des jeux electroniques (A French Lesson with Electronic Games).

    ERIC Educational Resources Information Center

    Malandain, Jean-Louis

    1996-01-01

    Electronic games are proposed as a means for encouraging students of French to learn and use the language while solving problems. A computerized card game and mine-removal game are offered as illustration of the language skills and vocabulary that can be developed and the appeal that such exercises can have for students. (MSE)

  18. Les Fonctionnaires Europeens et L'Apprentissage du Francais, Langue Etrangere. Melanges Pedagogiques, 1975.

    ERIC Educational Resources Information Center

    Mulfinger, F.

    This paper describes a teaching strategy involving authentic material in a semi-autonomous learning situation (European civil servants working in the Common Market Administrations in Brussels). A general description of the learners in terms of their backgrounds (ethnic, educational and social) and the conditions and surroundings of their learning…

  19. Francais sur objectif specifique: parier sur l'ouverture (French for Specific Purposes: Betting on Expansion).

    ERIC Educational Resources Information Center

    Couillerot, Jacques; Fariol, Hanna

    1990-01-01

    The description and summary of a large-scale French study of the future and directions of French-language teaching for special purposes looks at instructional efforts currently under way and at three aspects of the study: the publics addressed, the areas of specialization targeted, and the methods used. (MSE)

  20. Enseigner quel francais du tourisme (Which French to Teach for Tourism).

    ERIC Educational Resources Information Center

    Larsson, Bjorn

    1992-01-01

    Development of a course in French for tourism and the hotel industry in Sweden is chronicled, focusing on the process of functional analysis used to determine appropriate language content. A general functional outline of touristic French and an outline of language functions specific to a restaurant situation are presented. (MSE)

  1. Des citoyens francais a quatre pattes (Four-footed French Citizens).

    ERIC Educational Resources Information Center

    Champ-Renaud, Dominique

    1983-01-01

    A class activity is described involving a panel discussion of the role of dogs in French culture and related issues of public administration such as animal protection laws. Panel members' roles (public officials, veterinarians, etc.), audience roles (dog owner, father of a bitten child, etc.), and followup activities are outlined. (MSE)

  2. Informatique et francais langue etrangere (Information Science and French as a Foreign Language).

    ERIC Educational Resources Information Center

    Abry, Dominique; Scholl, Maryse

    1984-01-01

    An interdisciplinary experiment to develop materials for computer-assisted French instruction at the University of Grenoble is described and the process of translating objectives and strategies into exercises relying on student-machine interaction is chronicled. Three approaches were used: student response using stated rules, recognition…

  3. Francais: Langue de specialite: Gearing Commercial French for the World of 1992.

    ERIC Educational Resources Information Center

    Finel-Honigman, Irene

    In the area of business-related language training, the United States lags behind Europe, where graduate business schools require at least one foreign language with business proficiency for graduation. In most United States institutions, the long-standing policy of departmentalization and a perceived dichotomy between the humanities and traditional…

  4. "L'unilinguisme" francais contre le changement sociolinguistique (French "Unilingualism" versus Sociolinguistic Change).

    ERIC Educational Resources Information Center

    Boyer, Henri

    2001-01-01

    This article describes the French unilingual, also seen as a sociolinguistic ideology, in its varieties, especially since the French Revolution: an ideology based on few representations that are both inner and outer linguistic. The article also discusses the attitude of the unilingual in the collective epilinguistic field of experiment. One…

  5. Chine: Les Chances du Francais (The Fortunes of the French Language in China).

    ERIC Educational Resources Information Center

    Shuning, Zhang

    1996-01-01

    Examines the current situation in China surrounding the teaching of French as a Foreign Language. After the decline of French teaching subsequent to the Cultural Revolution, the language returned to favor around 1970. Chinese students are infatuated with French; many study it as a first or second foreign language. Additionally, French literature…

  6. Le Francais des Professions Scientifiques et Techniques (French for the Scientific and Technical Professions).

    ERIC Educational Resources Information Center

    Muller, Brigitte

    Two sequential courses in scientific and technical French developed as a supplement to third- and fourth-year college French, in response to expressed student and industry demand, had as their objectives to develop a general familiarity with products of the large French industrial companies and their United States affiliates and to develop means…

  7. Bibliographie pour enseigner le francais des affaires (Bibliography for Business French Instruction).

    ERIC Educational Resources Information Center

    Dewey, S. Pascale

    This bibliography contains a list of various publications (books, journals, dictionaries, newspapers, magazines) as well as videos, CD-ROMs, Web sites, and the addresses of several French chambers of commerce that would be useful for any English speakers needing to live, do business, or otherwise spend time in France. References are in French or…

  8. L'Enseignement du francais commercial et ses problemes (Business French Instruction and Its Problems).

    ERIC Educational Resources Information Center

    Verger Michael, Colette

    1981-01-01

    Describes the Business French program of Northern Illinois University and discusses the problems that led to the adoption of an interdisciplinary approach involving the Department of Foreign Languages and the Business School. Reviews several textbooks and technical dictionaries and provides an extensive bibliography of business communication…

  9. L'enseignement du francais par ordinateur: Les programmes conversationnels au Cafe (Cours autodidactique de francais ecrit) [Teaching French by Computer: Conversational Programs in "Cafe" (Self-instructional Course in Written French)].

    ERIC Educational Resources Information Center

    Landriault, Bernard; Connolly, Guy

    1980-01-01

    Computer technology has been used to develop "Cafe," a self-instructional course in written French communication, which is offered to the general public by the University of Montreal. The course consists of three workbooks containing 1200 items dealing with vocabulary, spelling, punctuation, agreements, morphology, syntax, and fine points of…

  10. Le vocabulaire disponible du francais, Tome 1. Le vocabulaire concret usuel des enfants francais et acadiens: Etude temoin (The Working French Vocabulary, Volume 1. Common Generic Terms Used by French and Acadian Children: A Field Study).

    ERIC Educational Resources Information Center

    Mackey, William F.; And Others

    The first of a two-volume study of the relative accessibility of French vocabulary in French-speaking Canada presents statistical data concerning the frequency, distribution, valence, and accessibility of vocabulary related to 16 fundamental centers of interest found in normal conversation. The scope, procedures, and results of the study are…

  11. De la television pour comprendre les Francais: cours experimental (Understanding the French Through a Study of Television: An Experimental Course).

    ERIC Educational Resources Information Center

    Mariet, Francois

    1986-01-01

    A college French civilization course based on the important role of television in French contemporary culture, as formative of cultural habits, and on its similar importance to contemporary American students is described. (MSE)

  12. Theatre et enseignement du francais, langue etrangere (Theater and the Teaching of French as a Foreign Language).

    ERIC Educational Resources Information Center

    Maldaner, Aurea

    1980-01-01

    Discusses drama in foreign language instruction, especially as a means of improving oral expression. Two basic approaches are outlined and three techniques that have been used successfully with various age groups are described. (AMH)

  13. Vers un renouveau du "mirage americain" dans les lettres francais (Toward a Renewal of the "American Mirage" in French Literature)

    ERIC Educational Resources Information Center

    Huvos, Kornel

    1973-01-01

    Social and political commentary on the alternating images of America projected in French writing through the years; revised version of a paper presented at the 25th Annual Kentucky Foreign Language Conference, Lexington, Kentucky, April 28, 1972. (RL)

  14. Techniques de Theatre Integrees a l'Enseignement du Francais 1989 = Theatre Techniques Integrated into the Teaching of French, 1989.

    ERIC Educational Resources Information Center

    Parent, Roger

    This curriculum guide presents a methodology for teaching language and literature through role-playing in the classroom and demonstrates to teachers the link that exists between effective communication and the techniques used to achieve it. The new French program views language as an instrument of communication, a concept that implies that…

  15. L'anglophone et l'apprentissage du passe en francais (The French Past Tenses and the English Speaking Learner).

    ERIC Educational Resources Information Center

    Moore, Victoria

    1981-01-01

    Discusses the difficulties English speakers experience in using correctly the various tenses of the past in French, focusing particularly on the imperfect tense. Proposes a series of exercises based on contrastive analysis that gradually lead the learner to restructure his intuitive grammar. (MES)

  16. Pour une typologie des anglicismes en francais du Canada (Toward a Typology of Anglicisms in Canadian French).

    ERIC Educational Resources Information Center

    Meney, Lionel

    1994-01-01

    It is argued that anglicisms in Canadian French cover a much broader spectrum than in any European variety of French, with traits of the English language incorporated into spelling, pronunciation, morphology, syntax, lexicon, and phraseology. A typology of these features is proposed, with examples. (Author/MSE)

  17. Images de la variation du francais: dominantes et harmoniques, changements (Images of Variation in French: Dominant and Harmonic, Changes).

    ERIC Educational Resources Information Center

    Castellotti, Veronique; De Robillard, Didier

    2001-01-01

    This study gathered knowledge on an ill-explored field: attitudes toward French in France. It discusses ways and means to produce empirical data on this issue. Data indicate that the field described deserves investigation because, alongside standard French, the other "parlure" sampled in this study produce a variety of different attitudes and…

  18. Le francais assiste par ordinateur des colleges et des universities du Canada (French CALL in Canadian Colleges and Universities).

    ERIC Educational Resources Information Center

    Bougaieff, Andre

    This directory presents the results of a national survey of Canadian colleges and universities concerning faculty's use of computer-assisted French language instruction. The listings, arranged alphabetically by province or territory, and within these by institution, contain the responding faculty member's name, address, e-mail address, fax and…

  19. Le francais c'est le last frontier: The Status of English-Origin Nouns in Acadian French.

    ERIC Educational Resources Information Center

    Turpin, Danielle

    1998-01-01

    Categorization of lone lexical items from one language embedded in another is often difficult due to their ambiguous status as either loanwords or codeswitches. Following variationist principles, a comparative method is used to disambiguate lone English-origin nouns in Acadian-French discourse. (Author/VWL)

  20. Planification de l'enseignement du francais a l'elementaire: Immersion (Planning French Instruction at the Elementary Level: Immersion).

    ERIC Educational Resources Information Center

    Lavoie, Jacinthe

    A shift in instructional focus to student needs and interests spurred the development of a different approach to French second language program design in Alberta. A practical curriculum planning model is offered that is based on: (1) communicative and student-centered activities; (2) responsiveness to teacher needs; and (3) supporting planning for…

  1. La publicite et l'enseignement du francais langue etrangere (Advertising and the Teaching of French as a Second Language).

    ERIC Educational Resources Information Center

    Margerie, Charles de

    1981-01-01

    Reviews the history of the use of advertisements as instructional material, indicating that they appear almost exclusively in advanced level textbooks for adults and that they are seldom exploited according to clearly defined objectives. Discusses various modes of utilization and suggests criteria for the selection of such materials. (MES)

  2. PARCS: A Safety Net Community-Based Fitness Center for Low-Income Adults

    PubMed Central

    Keith, NiCole; de Groot, Mary; Mi, Deming; Alexander, Kisha; Kaiser, Stephanie

    2015-01-01

    Background Physical activity (PA) and fitness are critical to maintaining health and avoiding chronic disease. Limited access to fitness facilities in low-income urban areas has been identified as a contributor to low PA participation and poor fitness. Objectives This research describes community-based fitness centers established for adults living in low-income, urban communities and characterizes a sample of its members. Methods The community identified a need for physical fitness opportunities to improve residents’ health. Three community high schools were host sites. Resources were combined to renovate and staff facilities, acquire equipment, and refer patients to exercise. The study sample included 170 members ≥ age 18yr who completed demographic, exercise self-efficacy, and quality of life surveys and a fitness evaluation. Neighborhood-level U.S. Census data were obtained for comparison. Results The community-based fitness centers resulted from university, public school, and hospital partnerships offering safe, accessible, and affordable exercise opportunities. The study sample mean BMI was 35 ± 7.6 (Class II obesity), mean age was 50yr ± 12.5, 66% were black, 72% were female, 66% completed some college or greater, and 71% had an annual household income < $25K and supported 2.2 dependents. Participants had moderate confidence for exercise participation and low fitness levels. When compared to census data, participants were representative of their communities. Conclusion This observational study reveals a need for affordable fitness centers for low-income adults. We demonstrate a model where communities and organizations strategically leverage resources to address disparities in physical fitness and health. PMID:27346764

  3. Status of the RF-driven H- ion source for J-PARC linac

    NASA Astrophysics Data System (ADS)

    Oguri, H.; Ohkoshi, K.; Ikegami, K.; Takagi, A.; Asano, H.; Ueno, A.; Shibata, T.

    2016-02-01

    For the upgrade of the Japan Proton Accelerator Research Complex linac beam current, a cesiated RF-driven negative hydrogen ion source was installed during the 2014 summer shutdown period, with subsequent operations commencing on September 29, 2014. The ion source has been successfully operating with a beam current and duty factor of 33 mA and 1.25% (500 μs and 25 Hz), respectively. The result of recent beam operation has demonstrated that the ion source is capable of continuous operation for approximately 1100 h. The spark rate at the beam extractor was observed to be at a frequency of less than once a day, which is an acceptable level for user operation. Although an antenna failure occurred during operation on October 26, 2014, no subsequent serious issues have occurred since then.

  4. Planification de la maintenance d'un parc de turbines-alternateurs par programmation mathematique

    NASA Astrophysics Data System (ADS)

    Aoudjit, Hakim

    A growing number of Hydro-Quebec's hydro generators are at the end of their useful life and maintenance managers fear to face a number of overhauls exceeding what can be handled. Maintenance crews and budgets are limited and these withdrawals may take up to a full year and mobilize significant resources in addition to the loss of electricity production. In addition, increased export sales forecasts and severe production patterns are expected to speed up wear that can lead to halting many units at the same time. Currently, expert judgment is at the heart of withdrawals which rely primarily on periodic inspections and in-situ measurements and the results are sent to the maintenance planning team who coordinate all the withdrawals decisions. The degradations phenomena taking place is random in nature and the prediction capability of wear using only inspections is limited to short-term at best. A long term planning of major overhauls is sought by managers for the sake of justifying and rationalizing budgets and resources. The maintenance managers are able to provide a huge amount of data. Among them, is the hourly production of each unit for several years, the repairs history on each part of a unit as well as major withdrawals since the 1950's. In this research, we tackle the problem of long term maintenance planning for a fleet of 90 hydro generators at Hydro-Quebec over a 50 years planning horizon period. We lay a scientific and rational framework to support withdrawals decisions by using part of the available data and maintenance history while fulfilling a set of technical and economic constraints. We propose a planning approach based on a constrained optimization framework. We begin by decomposing and sorting hydro generator components to highlight the most influential parts. A failure rate model is developed to take into account the technical characteristics and unit utilization. Then, replacement and repair policies are evaluated for each of the components then strategies are derived for the whole unit. Traditional univariate policies such as the age replacement policy and the minimal repair policy are calculated. These policies are extended to build alternative bivariate maintenance policy as well as a repair strategy where the state of a component after a repair is rejuvenated by a constant coefficient. These templates form the basis for the calculation of objective function for the scheduling problem. On one hand, this issue is treated as a nonlinear problem where the objective is to minimize the average total maintenance cost per unit of time on an infinite horizon for the fleet with technical and economic constraints. A formulation is also proposed in the case of a finite time horizon. In the event of electricity production variation, and given that the usage profile is known, the influence of production scenarios is reflected on the unit's components through their failure rate. In this context, prognoses on possible resources problems are made by studying the characteristics of the generated plans. On the second hand, the withdrawals are now subjected to two decision criteria. In addition to minimizing the average total maintenance cost per unit of time on an infinite time horizon, the best achievable reliability of remaining turbo generators is sought. This problem is treated as a biobjective nonlinear optimization problem. Finally a series of problems describing multiple contexts are solved for planning renovations of 90 turbo generators units considering 3 major components in each unit and 2 types of maintenance policies for each component.

  5. Performance of the HBD for the J-PARC E16 experiment

    NASA Astrophysics Data System (ADS)

    Kanno, Koki; J-PARC E16 Collaboration

    2014-09-01

    A Hadron Blind Detector (HBD) is a mirror-less and window-less Čerenkov detector for an electron identification. It consists of a radiator operated with pure CF4, a UV-photon sensitive GEM detector which is directly coupled to the radiator, and a pad readout. The GEM detector consists of a triple-GEM stack on top of which CsI is evaporated. The number of photoelectrons that the HBD can detect per incident electron is the most important value, since it discriminates electrons from other charged particles by using pad charge information. We have developed two types of large GEM foils (30 × 30 cm2) which have different hole pitches to optimize a hole/pitch ratio. We performed a beam test with 1.0 GeV/ c positrons at Research Center for Electron Photon Science, Tohoku University. We observed ~7.6 photoelectrons with 55 (hole diameter in copper (μm))/140 (hole pitch (μm)) GEM foils and ~10.7 photoelectrons with 55/110-GEM foils. The results are consistent with the expected result calculated based on the performance of each detector element. Additionally, our GEM foils provide a trigger. Developments of a readout circuit for a trigger is in progress.

  6. Polarisation Analysis Neutron Spectrometer, POLANO, at J-PARC - Concept and Magnetic Field Optimisation

    NASA Astrophysics Data System (ADS)

    Ohoyama, K.; Yokoo, T.; Itoh, S.; Nanbu, M.; Iwasa, K.; Ohkawara, M.; Kaneko, N.; Ino, T.; Hayashida, H.; Oku, T.; Kira, H.; Tasaki, S.; Takeda, M.; Kimura, H.; Sato, T. J.

    2016-04-01

    The status of the polarised neutron spectrometer constructed at the Japan Proton Accelerator Research Complex through a collaboration between Tohoku University and KEK will be reported. In particular, the optimisation of magnetic fields to minimise neutron- beam depolarisation using the finite element method will be discussed on the basis of several simulations using the finite element method.

  7. Pulsed ultra-cold neutron production using a Doppler shifter at J-PARC

    NASA Astrophysics Data System (ADS)

    Imajo, S.; Mishima, K.; Kitaguchi, M.; Iwashia, Y.; Yamada, N. L.; Hino, M.; Oda, T.; Ino, T.; Shimizu, H. M.; Yamashita, S.; Katayama, R.

    2016-01-01

    We have constructed a Doppler-shifter-type pulsed ultra-cold neutron (UCN) source at the Materials and Life Science Experiment Facility of the Japan Proton Accelerator Research Complex. Very cold neutrons (VCNs) with 136 m s^{-1} velocity in a neutron beam supplied by a pulsed neutron source are decelerated by reflection on an m=10 wide-band multilayer mirror, yielding pulsed UCNs. The mirror is fixed to the tip of a 2000 rpm rotating arm moving with 68 m s^{-1} velocity in the same direction as the VCNs. The repetition frequency of the pulsed UCNs is 8.33 Hz and the time width of the pulse at production is 4.4 ms. In order to increase the UCN flux, a supermirror guide, wide-band monochromatic mirrors, focus guides, and a UCN extraction guide have been newly installed or improved. The 1 MW-equivalent count rate of the output neutrons with longitudinal wavelengths longer than 58 nm is 1.6 × 102 cps, while that of the true UCNs is 80 cps. The spatial density at production is 1.4 UCN cm^{-3}. This new UCN source enables us to research and develop apparatuses necessary for the investigation of the neutron electric dipole moment.

  8. Development of the charge exchange type beam scraper system at the J-PARC

    NASA Astrophysics Data System (ADS)

    Okabe, K.; Yamamoto, K.; Kinsho, M.

    2016-03-01

    Improvement in injection beam quality at the Japan Proton Accelerator Research Complex 3-GeV rapid cycle synchrotron is to mitigate beam loss at the injection section. We developed a charge-exchange type scraper system with a thin carbon foil to collimate the beam halo in the injection beam line of the synchrotron. The key issue to realize the scraper is a reduction of the beam loss induced by the multiple-scattering effect of charge-exchange foil placed at the scraper head. In order to determine the adequate foil thickness, a charge-exchange efficiency of a carbon foil and particle-tracking simulation study of the collimated beam have been performed assuming a realistic halo at the scraper section. Using the results of this study, we chose the thickness of a 520 μg /cm2 as the scraper foils to mitigate radiation dose around the L3BT scraper section. A charge-exchange scraper system that prevents the emission of radioactive fragments of the carbon foil was build. The system was put into operation to prove its effectiveness in eliminating the beam halo. From the result of a preliminary beam experiments, we confirmed that the installed scrapers eliminate a transverse beam tail or halo. After two days of operation with beam collimation, the radiation dose level around the scraper section was a tolerable one for the hands-on maintenance.

  9. Status of the RF-driven H⁻ ion source for J-PARC linac.

    PubMed

    Oguri, H; Ohkoshi, K; Ikegami, K; Takagi, A; Asano, H; Ueno, A; Shibata, T

    2016-02-01

    For the upgrade of the Japan Proton Accelerator Research Complex linac beam current, a cesiated RF-driven negative hydrogen ion source was installed during the 2014 summer shutdown period, with subsequent operations commencing on September 29, 2014. The ion source has been successfully operating with a beam current and duty factor of 33 mA and 1.25% (500 μs and 25 Hz), respectively. The result of recent beam operation has demonstrated that the ion source is capable of continuous operation for approximately 1100 h. The spark rate at the beam extractor was observed to be at a frequency of less than once a day, which is an acceptable level for user operation. Although an antenna failure occurred during operation on October 26, 2014, no subsequent serious issues have occurred since then. PMID:26932020

  10. Problemes d'analyse du discours. Essai de description du discours francais sur la Chine (Problems in Discourse Analysis. An Attempt to Describe French Discourse on China).

    ERIC Educational Resources Information Center

    Marindin, Jean-Marie

    1979-01-01

    The following topics are developed: (1) the problematic aspect of the analysis of French discourse, an introduction to methods, theories and applications; (2) the proposals of M. Pecheux; (3) precisions to render operative definitions derived in the proposals; (4) the Macciocchi manner of speaking; and (5) the Peyrefitte manner of speaking. (AMH)