Sample records for partial safety analysis

  1. Partial Safety Analysis for a Reduced Uranium Enrichment Core for the High Flux Isotope Reactor

    SciTech Connect

    Primm, Trent [ORNL; Gehin, Jess C [ORNL

    2009-04-01

    A computational model of the reactor core of the High Flux Isotope Rector (HFIR) was developed in order to analyze non-destructive accidents caused by transients during reactor operation. The reactor model was built for the latest version of the nuclear analysis software package called Program for the Analysis of Reactor Transients (PARET). Analyses performed with the model constructed were compared with previous data obtained with other tools in order to benchmark the code. Finally, the model was used to analyze the behavior of the reactor under transients using a different nuclear fuel with lower enrichment of uranium (LEU) than the fuel currently used, which has a high enrichment of uranium (HEU). The study shows that the presence of fertile isotopes in LEU fuel, which increases the neutron resonance absorption, reduces the impact of transients on the fuel and enhances the negative reactivity feedback, thus, within the limitations of this study, making LEU fuel appear to be a safe alternative fuel for the reactor core.

  2. Partial Differential Equation Analysis in

    E-print Network

    Gilchrist, James F.

    Partial Differential Equation Analysis in Biomedical Engineering PartialDifferentialEquationAnalysisin BiomedicalEngineering Partial Differential Equation Analysis in Biomedical Engineering Case Studies in biomedical engineering. Taking an applied approach, rather than using abstract mathematics, the reader

  3. Safety analysis

    NASA Technical Reports Server (NTRS)

    Knight, John C.

    1995-01-01

    We are engaged in a research program in safety-critical computing that is based on two case studies. We use these case studies to provide application-specific details of the various research issues, and as targets for evaluation of research ideas. The first case study is the Magnetic Stereotaxis System (MSS), an investigational device for performing human neurosurgery being developed in a joint effort between the Department of Physics at the University of Virginia and the Department of Neurosurgery at the University of Iowa. The system operates by manipulating a small permanent magnet (known as a 'seed') within the brain using an externally applied magnetic field. By varying the magnitude and gradient of the external magnetic field, the seed can be moved along a non-linear path and positioned at a site requiring therapy, e.g., a tumor. The magnetic field required for movement through brain tissue is extremely high, and is generated by a set of six superconducting magnets located in a housing surrounding the patient's head. The system uses two X-ray cameras positioned at right angles to detect in real time the locations of the seed and of X-ray opaque markers affixed to the patient's skull. the X-ray images are used to locate the objects of interest in a canonical frame of reference. the second case study is the University of Virginia Research Nuclear Reactor (UVAR). It is a 2 MW thermal, concrete-walled pool reactor. The system operates using 20 to 25 plate-type fuel assemblies placed on a rectangular grid plate. There are three scramable safety rods, and one non-scramable regulating rod that can be put in automatic mode. It was originally constructed in 1959 as a 1 MW system, and it was upgraded to 2 MW in 1973. Though only a research reactor rather than a power reactor, the issues raised are significant and can be related to the problems faced by full-scale reactor systems.

  4. Partial pressure analysis of plasmas

    SciTech Connect

    Dylla, H.F.

    1984-11-01

    The application of partial pressure analysis for plasma diagnostic measurements is reviewed. A comparison is made between the techniques of plasma flux analysis and partial pressure analysis for mass spectrometry of plasmas. Emphasis is given to the application of quadrupole mass spectrometers (QMS). The interface problems associated with the coupling of a QMS to a plasma device are discussed including: differential-pumping requirements, electromagnetic interferences from the plasma environment, the detection of surface-active species, ion source interactions, and calibration procedures. Example measurements are presented from process monitoring of glow discharge plasmas which are useful for cleaning and conditioning vacuum vessels.

  5. Finding safety in partially controllable chaotic systems Juan Sabuco a,

    E-print Network

    Rey Juan Carlos, Universidad

    Finding safety in partially controllable chaotic systems Juan Sabuco a, , Samuel Zambrano b such that partially controlled trajectories qnþ1 ¼ fðqnÞ þ nn þ un ð3Þ can guarantee that qn remain in Q the goal is to find a feedback control algorithm uðxÞ so that un ¼ uðfðqnÞ þ nnÞ. We make four assumptions

  6. Partial truths in the pursuit of patient safety

    Microsoft Academic Search

    Kerm Henriksen

    2010-01-01

    The paper explores several issues in the form of partial truths that dominate current thinking as investigators continue their pursuit of patient safety. Among the partial truths examined—cast as bipolar orientations—are evidence-based medicine versus quality improvement, ‘knowledge in the head’ versus ‘knowledge in the world’, sharp end versus blunt end, reporting systems versus local knowledge, changing beliefs versus changing behaviour

  7. Software safety hazard analysis

    SciTech Connect

    Lawrence, J.D. [Lawrence Livermore National Lab., CA (United States)

    1996-02-01

    Techniques for analyzing the safety and reliability of analog-based electronic protection systems that serve to mitigate hazards in process control systems have been developed over many years, and are reasonably well understood. An example is the protection system in a nuclear power plant. The extension of these techniques to systems which include digital computers is not well developed, and there is little consensus among software engineering experts and safety experts on how to analyze such systems. One possible technique is to extend hazard analysis to include digital computer-based systems. Software is frequently overlooked during system hazard analyses, but this is unacceptable when the software is in control of a potentially hazardous operation. In such cases, hazard analysis should be extended to fully cover the software. A method for performing software hazard analysis is proposed in this paper.

  8. Digital analysis of partial discharges

    Microsoft Academic Search

    Edward Gulski

    1995-01-01

    In this paper relevant aspects of digital processing of partial discharge (PD) as measured by conventional PD detection methods are discussed. Moreover, a systematic study of PD quantities is presented and discussed within the scope of practical PD analyzers, including recognition of defects in certain HV insulation configurations

  9. Model-Based Safety Analysis

    NASA Technical Reports Server (NTRS)

    Joshi, Anjali; Heimdahl, Mats P. E.; Miller, Steven P.; Whalen, Mike W.

    2006-01-01

    System safety analysis techniques are well established and are used extensively during the design of safety-critical systems. Despite this, most of the techniques are highly subjective and dependent on the skill of the practitioner. Since these analyses are usually based on an informal system model, it is unlikely that they will be complete, consistent, and error free. In fact, the lack of precise models of the system architecture and its failure modes often forces the safety analysts to devote much of their effort to gathering architectural details about the system behavior from several sources and embedding this information in the safety artifacts such as the fault trees. This report describes Model-Based Safety Analysis, an approach in which the system and safety engineers share a common system model created using a model-based development process. By extending the system model with a fault model as well as relevant portions of the physical system to be controlled, automated support can be provided for much of the safety analysis. We believe that by using a common model for both system and safety engineering and automating parts of the safety analysis, we can both reduce the cost and improve the quality of the safety analysis. Here we present our vision of model-based safety analysis and discuss the advantages and challenges in making this approach practical.

  10. Integrated Safety Analysis Teams

    NASA Technical Reports Server (NTRS)

    Wetherholt, Jonathan C.

    2008-01-01

    Today's complex systems require understanding beyond one person s capability to comprehend. Each system requires a team to divide the system into understandable subsystems which can then be analyzed with an Integrated Hazard Analysis. The team must have both specific experiences and diversity of experience. Safety experience and system understanding are not always manifested in one individual. Group dynamics make the difference between success and failure as well as the difference between a difficult task and a rewarding experience. There are examples in the news which demonstrate the need to connect the pieces of a system into a complete picture. The Columbia disaster is now a standard example of a low consequence hazard in one part of the system; the External Tank is a catastrophic hazard cause for a companion subsystem, the Space Shuttle Orbiter. The interaction between the hardware, the manufacturing process, the handling, and the operations contributed to the problem. Each of these had analysis performed, but who constituted the team which integrated this analysis together? This paper will explore some of the methods used for dividing up a complex system; and how one integration team has analyzed the parts. How this analysis has been documented in one particular launch space vehicle case will also be discussed.

  11. Partial state routers: design, analysis and evaluation

    E-print Network

    Achanta, Phani Gopal V

    2002-01-01

    INTRODUCTION A. Motivation . B. Previous Work . 1. Stateless Active Queue Management Schemes . 2. Stateful Active Queue Management Schemes 3. Packet State Active Queue Management Schemes . 4. Partial State Based Active Queue Management Schemes 5. Denial... of Service Solutions C. Observations . D. Organization . LRU-FQ: DESIGN AND IMPLEMENTATION . A. Requirements B. LRU-FQ: The Scheme C. Possible Applications of LRU-FQ Scheme . D. LRU Analysis 1. Worst-case Analysis 2. Analysis Results E. The Linux...

  12. 14 CFR 33.75 - Safety analysis.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...must be included in the analysis. Such a safety system may include safety devices, instrumentation, early warning devices, maintenance checks...equipment or procedures. If items of a safety system are outside the control of the engine...

  13. 14 CFR 33.75 - Safety analysis.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...must be included in the analysis. Such a safety system may include safety devices, instrumentation, early warning devices, maintenance checks...equipment or procedures. If items of a safety system are outside the control of the engine...

  14. 14 CFR 33.75 - Safety analysis.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...must be included in the analysis. Such a safety system may include safety devices, instrumentation, early warning devices, maintenance checks...equipment or procedures. If items of a safety system are outside the control of the engine...

  15. 14 CFR 33.75 - Safety analysis.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...must be included in the analysis. Such a safety system may include safety devices, instrumentation, early warning devices, maintenance checks...equipment or procedures. If items of a safety system are outside the control of the engine...

  16. 14 CFR 33.75 - Safety analysis.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...must be included in the analysis. Such a safety system may include safety devices, instrumentation, early warning devices, maintenance checks...equipment or procedures. If items of a safety system are outside the control of the engine...

  17. Measuring Safety Performance: A Comparison of Whole, Partial, and Momentary Time-Sampling Recording Methods

    ERIC Educational Resources Information Center

    Alvero, Alicia M.; Struss, Kristen; Rappaport, Eva

    2008-01-01

    Partial-interval (PIR), whole-interval (WIR), and momentary time sampling (MTS) estimates were compared against continuous measures of safety performance for three postural behaviors: feet, back, and shoulder position. Twenty-five samples of safety performance across five undergraduate students were scored using a second-by-second continuous…

  18. Partial wave analysis of $J/?\\to ???$

    E-print Network

    M. Ablikim; M. N. Achasov; O. Albayrak; D. J. Ambrose; F. F. An; Q. An; J. Z. Bai; R. Baldini Ferroli; Y. Ban; J. Becker; J. V. Bennett; N. Berger; M. Bertani; J. M. Bian; E. Boger; O. Bondarenko; I. Boyko; R. A. Briere; V. Bytev; H. Cai; X. Cai; O. Cakir; A. Calcaterra; G. F. Cao; S. A. Cetin; J. F. Chang; G. Chelkov; G. Chen; H. S. Chen; J. C. Chen; M. L. Chen; S. J. Chen; X. Chen; Y. B. Chen; H. P. Cheng; Y. P. Chu; D. Cronin-Hennessy; H. L. Dai; J. P. Dai; D. Dedovich; Z. Y. Deng; A. Denig; I. Denysenko; M. Destefanis; W. M. Ding; Y. Ding; L. Y. Dong; M. Y. Dong; S. X. Du; J. Fang; S. S. Fang; L. Fava; C. Q. Feng; P. Friedel; C. D. Fu; J. L. Fu; Y. Gao; C. Geng; K. Goetzen; W. X. Gong; W. Gradl; M. Greco; M. H. Gu; Y. T. Gu; Y. H. Guan; A. Q. Guo; L. B. Guo; T. Guo; Y. P. Guo; Y. L. Han; F. A. Harris; K. L. He; M. He; Z. Y. He; T. Held; Y. K. Heng; Z. L. Hou; C. Hu; H. M. Hu; J. F. Hu; T. Hu; G. M. Huang; G. S. Huang; J. S. Huang; L. Huang; X. T. Huang; Y. Huang; Y. P. Huang; T. Hussain; C. S. Ji; Q. Ji; Q. P. Ji; X. B. Ji; X. L. Ji; L. L. Jiang; X. S. Jiang; J. B. Jiao; Z. Jiao; D. P. Jin; S. Jin; F. F. Jing; N. Kalantar-Nayestanaki; M. Kavatsyuk; B. Kopf; M. Kornicer; W. Kuehn; W. Lai; J. S. Lange; M. Leyhe; C. H. Li; Cheng Li; Cui Li; D. M. Li; F. Li; G. Li; H. B. Li; J. C. Li; K. Li; Lei Li; Q. J. Li; S. L. Li; W. D. Li; W. G. Li; X. L. Li; X. N. Li; X. Q. Li; X. R. Li; Z. B. Li; H. Liang; Y. F. Liang; Y. T. Liang; G. R. Liao; X. T. Liao; D. Lin; B. J. Liu; C. L. Liu; C. X. Liu; F. H. Liu; Fang Liu; Feng Liu; H. Liu; H. B. Liu; H. H. Liu; H. M. Liu; H. W. Liu; J. P. Liu; K. Liu; K. Y. Liu; Kai Liu; P. L. Liu; Q. Liu; S. B. Liu; X. Liu; Y. B. Liu; Z. A. Liu; Zhiqiang Liu; Zhiqing Liu; H. Loehner; G. R. Lu; H. J. Lu; J. G. Lu; Q. W. Lu; X. R. Lu; Y. P. Lu; C. L. Luo; M. X. Luo; T. Luo; X. L. Luo; M. Lv; C. L. Ma; F. C. Ma; H. L. Ma; Q. M. Ma; S. Ma; T. Ma; X. Y. Ma; F. E. Maas; M. Maggiora; Q. A. Malik; Y. J. Mao; Z. P. Mao; J. G. Messchendorp; J. Min; T. J. Min; R. E. Mitchell; X. H. Mo; C. Morales Morales; N. Yu. Muchnoi; H. Muramatsu; Y. Nefedov; C. Nicholson; I. B. Nikolaev; Z. Ning; S. L. Olsen; Q. Ouyang; S. Pacetti; J. W. Park; M. Pelizaeus; H. P. Peng; K. Peters; J. L. Ping; R. G. Ping; R. Poling; E. Prencipe; M. Qi; S. Qian; C. F. Qiao; L. Q. Qin; X. S. Qin; Y. Qin; Z. H. Qin; J. F. Qiu; K. H. Rashid; G. Rong; X. D. Ruan; A. Sarantsev; B. D. Schaefer; M. Shao; C. P. Shen; X. Y. Shen; H. Y. Sheng; M. R. Shepherd; X. Y. Song; S. Spataro; B. Spruck; D. H. Sun; G. X. Sun; J. F. Sun; S. S. Sun; Y. J. Sun; Y. Z. Sun; Z. J. Sun; Z. T. Sun; C. J. Tang; X. Tang; I. Tapan; E. H. Thorndike; D. Toth; M. Ullrich; I. U. Uman; G. S. Varner; B. Q. Wang; D. Wang; D. Y. Wang; K. Wang; L. L. Wang; L. S. Wang; M. Wang; P. Wang; P. L. Wang; Q. J. Wang; S. G. Wang; X. F. Wang; X. L. Wang; Y. D. Wang; Y. F. Wang; Y. Q. Wang; Z. Wang; Z. G. Wang; Z. Y. Wang; D. H. Wei; J. B. Wei; P. Weidenkaff; Q. G. Wen; S. P. Wen; M. Werner; U. Wiedner; L. H. Wu; N. Wu; S. X. Wu; W. Wu; Z. Wu; L. G. Xia; Y. X. Xia; Z. J. Xiao; Y. G. Xie; Q. L. Xiu; G. F. Xu; G. M. Xu; Q. J. Xu; Q. N. Xu; X. P. Xu; Z. R. Xu; F. Xue; Z. Xue; L. Yan; W. B. Yan; Y. H. Yan; H. X. Yang; Y. Yang; Y. X. Yang; H. Ye; M. Ye; M. H. Ye; B. X. Yu; C. X. Yu; H. W. Yu; J. S. Yu; S. P. Yu; C. Z. Yuan; Y. Yuan; A. A. Zafar; A. Zallo; Y. Zeng; B. X. Zhang; B. Y. Zhang; C. Zhang; C. C. Zhang; D. H. Zhang; H. H. Zhang; H. Y. Zhang; J. Q. Zhang; J. W. Zhang; J. Y. Zhang; J. Z. Zhang; Li Li Zhang; R. Zhang; S. H. Zhang; X. J. Zhang; X. Y. Zhang; Y. Zhang; Y. H. Zhang; Z. P. Zhang; Z. Y. Zhang; Zhenghao Zhang; G. Zhao; H. S. Zhao; J. W. Zhao; K. X. Zhao; Lei Zhao; Ling Zhao; M. G. Zhao; Q. Zhao; Q. Z. Zhao; S. J. Zhao; T. C. Zhao; X. H. Zhao; Y. B. Zhao; Z. G. Zhao; A. Zhemchugov; B. Zheng; J. P. Zheng; Y. H. Zheng; B. Zhong; Z. Zhong; L. Zhou; X. Zhou; X. K. Zhou; X. R. Zhou; C. Zhu; K. Zhu; K. J. Zhu; S. H. Zhu; X. L. Zhu; Y. C. Zhu; Y. M. Zhu; Y. S. Zhu; Z. A. Zhu; J. Zhuang; B. S. Zou; J. H. Zou

    2013-01-01

    Based on a sample of $2.25\\times 10^{8}$ $J/\\psi$ events collected with the BESIII detector at BEPCII, a full partial wave analysis on $J/\\psi\\to\\gamma\\eta\\eta$ was performed using the relativistic covariant tensor amplitude method. The results show that the dominant $0^{++}$ and $2^{++}$ components are from the $f_0(1710)$, $f_0(2100)$, $f_0(1500)$, $f_2'(1525)$, $f_2(1810)$ and $f_2(2340)$. The resonance parameters and branching fractions are also presented.

  19. Job Safety Analysis College/Department/Unit

    E-print Network

    Saskatchewan, University of

    Job Safety Analysis (JSA) College/Department/Unit: Title of Job Activity: Oven Location of Activity and understanding the Job Safety Analysis: Date Name (Print) Signature #12;JSA # Page 3 Basic Job Steps Possible

  20. The new BNL partial wave analysis programs

    SciTech Connect

    Cummings, J.P.; Weygand, D.P.

    1997-07-29

    Experiment E852 at Brookhaven National Laboratory is a meson spectroscopy experiment which took data at the Multi-Particle Spectrometer facility of the Alternating Gradient Syncrotron. Upgrades to the spectrometer`s data acquisition and trigger electronics allowed over 900 million data events, of numerous topologies, to be recorded to tape in 1995 running alone. One of the primary goals of E852 is identification of states beyond the quark model, i.e., states with gluonic degrees of freedom. Identification of such states involves the measurement of a systems spin-parity. Such a measurement is usually done using Partial Wave Analysis. Programs to perform such analyses exist, in fact, one was written at BNL and used in previous experiments by some of this group. This program, however, was optimized for a particular final state, and modification to allow analysis of the broad range of final states in E852 would have been difficult. The authors therefore decided to write a new program, with an eye towards generality that would allow analysis of a large class of reactions.

  1. SAFETY ANALYSIS OFSAFETY ANALYSIS OF SOFTWARE PRODUCT LINES

    E-print Network

    Bae, Doo-Hwan

    SAFETY ANALYSIS OFSAFETY ANALYSIS OF SOFTWARE PRODUCT LINES USING STATE BASED MODELINGMODELING JIntroduction S f f 3 Software product line takes advantage of the reuse Safety analysis in software product line guided model analysis 2007-10-17 #12;Overview Approach Overview 8 State ModelingSafety analysisProduct

  2. The adaptive safety analysis and monitoring system

    NASA Astrophysics Data System (ADS)

    Tu, Haiying; Allanach, Jeffrey; Singh, Satnam; Pattipati, Krishna R.; Willett, Peter

    2004-09-01

    The Adaptive Safety Analysis and Monitoring (ASAM) system is a hybrid model-based software tool for assisting intelligence analysts to identify terrorist threats, to predict possible evolution of the terrorist activities, and to suggest strategies for countering terrorism. The ASAM system provides a distributed processing structure for gathering, sharing, understanding, and using information to assess and predict terrorist network states. In combination with counter-terrorist network models, it can also suggest feasible actions to inhibit potential terrorist threats. In this paper, we will introduce the architecture of the ASAM system, and discuss the hybrid modeling approach embedded in it, viz., Hidden Markov Models (HMMs) to detect and provide soft evidence on the states of terrorist network nodes based on partial and imperfect observations, and Bayesian networks (BNs) to integrate soft evidence from multiple HMMs. The functionality of the ASAM system is illustrated by way of application to the Indian Airlines Hijacking, as modeled from open sources.

  3. The Simplified Partial Digest Problem: Hardness and a Probabilistic Analysis

    E-print Network

    Pratt, Vaughan

    The Simplified Partial Digest Problem: Hardness and a Probabilistic Analysis Zoë Abrams1 and Ho site locations of the enzyme. Two common approaches are the Double Digest Problem and the Partial Digest Problem. The Double Digest Problem is known to be NP-Complete[4], but the hardness of the Partial

  4. 14 CFR 417.309 - Flight safety system analysis.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...2012-01-01 2012-01-01 false Flight safety system analysis. 417.309 Section 417.309 ...TRANSPORTATION LICENSING LAUNCH SAFETY Flight Safety System § 417.309 Flight safety system analysis. (a) General. (1) Each...

  5. 14 CFR 417.309 - Flight safety system analysis.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...2013-01-01 2013-01-01 false Flight safety system analysis. 417.309 Section 417.309 ...TRANSPORTATION LICENSING LAUNCH SAFETY Flight Safety System § 417.309 Flight safety system analysis. (a) General. (1) Each...

  6. 14 CFR 417.309 - Flight safety system analysis.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...2014-01-01 2014-01-01 false Flight safety system analysis. 417.309 Section 417.309 ...TRANSPORTATION LICENSING LAUNCH SAFETY Flight Safety System § 417.309 Flight safety system analysis. (a) General. (1) Each...

  7. Automation for System Safety Analysis

    NASA Technical Reports Server (NTRS)

    Malin, Jane T.; Fleming, Land; Throop, David; Thronesbery, Carroll; Flores, Joshua; Bennett, Ted; Wennberg, Paul

    2009-01-01

    This presentation describes work to integrate a set of tools to support early model-based analysis of failures and hazards due to system-software interactions. The tools perform and assist analysts in the following tasks: 1) extract model parts from text for architecture and safety/hazard models; 2) combine the parts with library information to develop the models for visualization and analysis; 3) perform graph analysis and simulation to identify and evaluate possible paths from hazard sources to vulnerable entities and functions, in nominal and anomalous system-software configurations and scenarios; and 4) identify resulting candidate scenarios for software integration testing. There has been significant technical progress in model extraction from Orion program text sources, architecture model derivation (components and connections) and documentation of extraction sources. Models have been derived from Internal Interface Requirements Documents (IIRDs) and FMEA documents. Linguistic text processing is used to extract model parts and relationships, and the Aerospace Ontology also aids automated model development from the extracted information. Visualizations of these models assist analysts in requirements overview and in checking consistency and completeness.

  8. 10 CFR 70.62 - Safety program and integrated safety analysis.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...complete an integrated safety analysis, correct all unacceptable...approval, an integrated safety analysis summary, including a description...C) Other site-specific factors which the Commission may consider...conduct of the integrated safety analysis, the licensee shall...

  9. 10 CFR 70.62 - Safety program and integrated safety analysis.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...complete an integrated safety analysis, correct all unacceptable...approval, an integrated safety analysis summary, including a description...C) Other site-specific factors which the Commission may consider...conduct of the integrated safety analysis, the licensee shall...

  10. Slope Safety Factor Analysis Using ANSYS

    Microsoft Academic Search

    Zhao Shangyi; Zheng Yingren

    This paper presents an analysis method for slope safety factor through soil shear strength reduction algorithm using finite elements. When the system reaches instability, the numerical non-convergence occurs simultaneously. The safety factor is obtained by strength reduction algorithm. The numerical convergence or non-convergence is related to the yield criterion. This paper presents an analysis and comparison of several yield criterions

  11. Hot Cell Facility (HCF) Safety Analysis Report

    SciTech Connect

    MITCHELL,GERRY W.; LONGLEY,SUSAN W.; PHILBIN,JEFFREY S.; MAHN,JEFFREY A.; BERRY,DONALD T.; SCHWERS,NORMAN F.; VANDERBEEK,THOMAS E.; NAEGELI,ROBERT E.

    2000-11-01

    This Safety Analysis Report (SAR) is prepared in compliance with the requirements of DOE Order 5480.23, Nuclear Safety Analysis Reports, and has been written to the format and content guide of DOE-STD-3009-94 Preparation Guide for U. S. Department of Energy Nonreactor Nuclear Safety Analysis Reports. The Hot Cell Facility is a Hazard Category 2 nonreactor nuclear facility, and is operated by Sandia National Laboratories for the Department of Energy. This SAR provides a description of the HCF and its operations, an assessment of the hazards and potential accidents which may occur in the facility. The potential consequences and likelihood of these accidents are analyzed and described. Using the process and criteria described in DOE-STD-3009-94, safety-related structures, systems and components are identified, and the important safety functions of each SSC are described. Additionally, information which describes the safety management programs at SNL are described in ancillary chapters of the SAR.

  12. Infusing Reliability Techniques into Software Safety Analysis

    NASA Technical Reports Server (NTRS)

    Shi, Ying

    2015-01-01

    Software safety analysis for a large software intensive system is always a challenge. Software safety practitioners need to ensure that software related hazards are completely identified, controlled, and tracked. This paper discusses in detail how to incorporate the traditional reliability techniques into the entire software safety analysis process. In addition, this paper addresses how information can be effectively shared between the various practitioners involved in the software safety analyses. The author has successfully applied the approach to several aerospace applications. Examples are provided to illustrate the key steps of the proposed approach.

  13. 10 CFR 830.204 - Documented safety analysis.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...prepare the documented safety analysis for the facility unless...b) The documented safety analysis for a hazard category 1...including the design of safety structures, systems and components...consideration of the need for analysis of accidents which may...

  14. 10 CFR 830.204 - Documented safety analysis.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...prepare the documented safety analysis for the facility unless...b) The documented safety analysis for a hazard category 1...including the design of safety structures, systems and components...consideration of the need for analysis of accidents which may...

  15. 10 CFR 830.204 - Documented safety analysis.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...prepare the documented safety analysis for the facility unless...b) The documented safety analysis for a hazard category 1...including the design of safety structures, systems and components...consideration of the need for analysis of accidents which may...

  16. 10 CFR 830.204 - Documented safety analysis.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...prepare the documented safety analysis for the facility unless...b) The documented safety analysis for a hazard category 1...including the design of safety structures, systems and components...consideration of the need for analysis of accidents which may...

  17. 10 CFR 830.204 - Documented safety analysis.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...prepare the documented safety analysis for the facility unless...b) The documented safety analysis for a hazard category 1...including the design of safety structures, systems and components...consideration of the need for analysis of accidents which may...

  18. Plutonium Uranium Extraction Facility Documented Safety Analysis

    SciTech Connect

    DODD, E.N.

    2003-10-08

    This document provides the documented safety analysis (DSA) and Central Plateau Remediation Project (CP) requirements that apply to surveillance and maintenance (S&M) activities at the Plutonium-Uranium Extraction (PUREX) facility. This DSA was developed in accordance with DOE-STD-1120-98, ''Integration of Environment, Safety, and Health into Facility Disposition Activities''. Upon approval and implementation of this document, the current safety basis documents will be retired.

  19. Contracting for Safety: A Concept Analysis

    Microsoft Academic Search

    Mary P. Egan

    1997-01-01

    The concept of contracting for safety, although a popularly accepted method for managing suicidal patients, has no scientific evidence to support its effectiveness. There are questions regarding the clinical justification. This article provides a concept analysis of contracting for safety to evolve and clarify exemplary criteria of the concept within psychiatric nursing practice. At times in clinical practice, contracting is

  20. Autoclave nuclear criticality safety analysis

    SciTech Connect

    D`Aquila, D.M. [Martin Marietta Energy Systems, Inc., Piketon, OH (United States); Tayloe, R.W. Jr. [Battelle, Columbus, OH (United States)

    1991-12-31

    Steam-heated autoclaves are used in gaseous diffusion uranium enrichment plants to heat large cylinders of UF{sub 6}. Nuclear criticality safety for these autoclaves is evaluated. To enhance criticality safety, systems are incorporated into the design of autoclaves to limit the amount of water present. These safety systems also increase the likelihood that any UF{sub 6} inadvertently released from a cylinder into an autoclave is not released to the environment. Up to 140 pounds of water can be held up in large autoclaves. This mass of water is sufficient to support a nuclear criticality when optimally combined with 125 pounds of UF{sub 6} enriched to 5 percent U{sup 235}. However, water in autoclaves is widely dispersed as condensed droplets and vapor, and is extremely unlikely to form a critical configuration with released UF{sub 6}.

  1. Analysis of partially converted lignocellulosic materials

    SciTech Connect

    Grandmaison, J.L.; Ahmed, A.; Kaliaguine, S.

    1987-04-01

    The systematic analysis of the solid residues of the supercritical methanol extraction of Populus tremuloides was performed for samples prepared at temperatures varying from 250 to 250C and pressures from 3.4 to 17.2 MPa, using such analytical techniques as wet chemistry, chromatography, thermogravimetric analysis, diffuse reflectance FTIR spectroscopy and photoelectron spectroscopy. The results allow to monitor the continuous changes in chemical composition of the samples from partly extracted wood samples to highly recondensed polyaromatic structures.

  2. Partial Wave Analysis of Coupled Photonic Structures

    NASA Technical Reports Server (NTRS)

    Fuller, Kirk A.; Smith, David D.; Curreri, Peter A. (Technical Monitor)

    2002-01-01

    The very high quality factors sustained by microcavity optical resonators are relevant to applications in wavelength filtering, routing, switching, modulation, and multiplexing/demultiplexing. Increases in the density of photonic elements require that attention be paid to how electromagnetic (EM) coupling modifies their optical properties. This is especially true when cavity resonances are involved, in which case, their characteristics may be fundamentally altered. Understanding the optical properties of microcavities that are near or in contact with photonic elements---such as other microcavities, nanostructures, couplers, and substrates---can be expected to advance our understanding of the roles that these structures may play in VLSI photonics, biosensors and similar device technologies. Wc present results from recent theoretical studies of the effects of inter- and intracavity coupling on optical resonances in compound spherical particles. Concentrically stratified spheres and bispheres constituted from homogeneous and stratified spheres are subjects of this investigation. A new formulation is introduced for the absorption of light in an arbitrary layer of a multilayered sphere, which is based on multiple reflections of the spherical partial waves of the Lorenz-Mie solution for scattering by a sphere. Absorption efficiencies, which can be used to profile cavity resonances and to infer fluorescence yields or the onset of nonlinear optical processes in the microcavities, are presented. Splitting of resonances in these multisphere systems is paid particular attention, and consequences for photonic device development and possible performance enhancements through carefully designed architectures that exploit EM coupling are considered.

  3. Partial fringe analysis applied to holographic interferometry 

    E-print Network

    Rathbun, Paul Alan

    1990-01-01

    Mathematics of Recording Interference CHAPTER III PREVIOUS 1VORK 10 Standard Holography and Fringe Analysis . . Heterodyne Holographic Interferometry Methods Digital Image Processing Methods . . 10 12 14 CHAPTER IV EXPERIMENTAL SETUP 15 Holographic... time or double. ? exposure HI 3 Standard holographic setup which can be used for double ? exposure holog- ra. phy . 11 4 Example of fringe ordering technique 5 Experisnental setup for heterodyne holography 12 13 6 Experimental setup for thesis 16...

  4. Transient analysis of a safety injection system

    SciTech Connect

    Squarer, D.; Kothmann, R.E.; Fagan, T.J. (Westinghouse Electric Corporation, Pittsburgh, PA (United States))

    1991-01-01

    A thermal-hydraulic analysis that can accurately predict the behavior of the supplementary safety system of the Westinghouse Savannah River Company reactors is discussed. The analysis was formulated from first principles, and a computer code was written to solve this problem. The fluid network analysis presented here is general and can be used to solve unrelated problems. The analysis and the computer code were verified by comparing the code predictions with the results of experiments designed especially for this purpose.

  5. Safety and efficacy of a partially covered self-expandable metal stent in benign pyloric obstruction

    PubMed Central

    Heo, Jun; Jung, Min Kyu

    2014-01-01

    AIM: To evaluate the safety and efficacy of partially covered self-expandable metallic stents (SEMSs) in benign pyloric obstruction. METHODS: We retrospectively analyzed data from 10 consecutive patients with peptic ulcer-related pyloric obstructive symptoms (gastric outlet obstruction scoring system (GOOSS) score of 1) between March 2012 and September 2013. The patients were referred to and managed by partially covered SEMS insertion in our tertiary academic center. We assessed the technical success, symptom improvement, and adverse events after stenting. RESULTS: Early symptoms were improved just 3 d after SEMS placement in all 10 patients. The GOOSS score of all patients improved from 1 to 3. There were no serious immediate adverse events. The overall rate of being symptom free was 90% at a median of 11 mo of follow-up (range: 4-43 mo). Five patients were managed by a rescue SEMS because of failure of previous endoscopic balloon dilatation. Among them, four patients had sustained symptom improvement after the SEMS procedure. During the follow-up period, migration of the SEMS was observed in two patients (20.0%), both of whom had previous endoscopic balloon dilatation before SEMS insertion. CONCLUSION: Despite the small number in this study, partially covered SEMSs showed a favorable and safe outcome in the treatment of naïve benign pyloric obstruction and in salvage treatment after balloon dilatation failure. PMID:25469043

  6. Partial analysis of experiment LDEF A-0114

    NASA Astrophysics Data System (ADS)

    Gregory, J. C.

    1986-05-01

    Due to delays in manifesting the return of the Long Duration Exposure Facility from space, attention was concentrated on extracting the maximum information from the EIOM-2 (oxygen interaction with materials experiment) flown on STS-8 in September 1983. An analysis was made of the optical surfaces exposed during that flight and an assessment made of the effect of the 5 eV atomic oxygen upon their physical and chemical properties. The surfaces studied were of two types: high-purity thin films sputtered or evaporated onto 2.54-cm diam lambda/20 fused silica optical flats, and highly polished bulk samples. Rapid etching of carbon and carbonaceous surfaces was observed with polycarbonate CR-39 showing the largest etch of any substrate flown and measured. Of the metals tested, only osmium and silver showed large effects, the former being heavily etched and the later forming a very thick layer of oxide. The first measurable effects on iridium, aluminum, nickel, tungsten and niobium thin films are reported.

  7. Waste Isolation Pilot Plant Safety Analysis Report

    SciTech Connect

    NONE

    1995-11-01

    The following provides a summary of the specific issues addressed in this FY-95 Annual Update as they relate to the CH TRU safety bases: Executive Summary; Site Characteristics; Principal Design and Safety Criteria; Facility Design and Operation; Hazards and Accident Analysis; Derivation of Technical Safety Requirements; Radiological and Hazardous Material Protection; Institutional Programs; Quality Assurance; and Decontamination and Decommissioning. The System Design Descriptions`` (SDDS) for the WIPP were reviewed and incorporated into Chapter 3, Principal Design and Safety Criteria and Chapter 4, Facility Design and Operation. This provides the most currently available final engineering design information on waste emplacement operations throughout the disposal phase up to the point of permanent closure. Also, the criteria which define the TRU waste to be accepted for disposal at the WIPP facility were summarized in Chapter 3 based on the WAC for the Waste Isolation Pilot Plant.`` This Safety Analysis Report (SAR) documents the safety analyses that develop and evaluate the adequacy of the Waste Isolation Pilot Plant Contact-Handled Transuranic Wastes (WIPP CH TRU) safety bases necessary to ensure the safety of workers, the public and the environment from the hazards posed by WIPP waste handling and emplacement operations during the disposal phase and hazards associated with the decommissioning and decontamination phase. The analyses of the hazards associated with the long-term (10,000 year) disposal of TRU and TRU mixed waste, and demonstration of compliance with the requirements of 40 CFR 191, Subpart B and 40 CFR 268.6 will be addressed in detail in the WIPP Final Certification Application scheduled for submittal in October 1996 (40 CFR 191) and the No-Migration Variance Petition (40 CFR 268.6) scheduled for submittal in June 1996. Section 5.4, Long-Term Waste Isolation Assessment summarizes the current status of the assessment.

  8. Hanford safety analysis and risk assessment handbook (SARAH)

    SciTech Connect

    GARVIN, L.J.

    2003-01-20

    The purpose of the Hanford Safety Analysis and Risk Assessment Handbook (SARAH) is to support the development of safety basis documentation for Hazard Category 1,2, and 3 U.S. Department of Energy (DOE) nuclear facilities. SARAH describes currently acceptable methodology for development of a Documented Safety Analysis (DSA) and derivation of technical safety requirements (TSR) based on 10 CFR 830, ''Nuclear Safety Management,'' Subpart B, ''Safety Basis Requirements,'' and provides data to ensure consistency in approach.

  9. Partial Component Analysis of a Comprehensive Smoking Program.

    ERIC Educational Resources Information Center

    Horan, John J.; Hackett, Gail

    The effects of a comprehensive program for the treatment of cigarette addiction were investigated. Subjects were 18 university students and 12 community members. Abstinence levels of 40 percent, verified by expired air carbon monoxide tests, were achieved in a six to nine month follow-up period. A partial component analysis revealed that the…

  10. Homotopy analysis method for solving fractional hyperbolic partial differential equations

    Microsoft Academic Search

    S. Das; P. K. Gupta

    2011-01-01

    In the present paper, the solutions of the hyperbolic partial differential equation with fractional time derivative of order ? (1analysis method. By using initial values, the explicit solutions of the equations for different particular cases have been derived which demonstrate the effectiveness, validity, potentiality

  11. Analysis of a Non-linear Partial Difference Equation, and

    E-print Network

    Rand, Richard H.

    Analysis of a Non-linear Partial Difference Equation, and Its Application to Cardiac Dynamics and Applied Mechanics, Cornell University, 212 Kimball Hall, Ithaca, NY 14853, USA; b Department of Physiology of a strip of cardiac tissue consisting of a one-dimensional chain of cardiac units is derived in the form

  12. SYNTHESIS OF SAFETY ANALYSIS AND FIRE HAZARD ANALYSIS METHODOLOGIES

    SciTech Connect

    Coutts, D

    2007-04-17

    Successful implementation of both the nuclear safety program and fire protection program is best accomplished using a coordinated process that relies on sound technical approaches. When systematically prepared, the documented safety analysis (DSA) and fire hazard analysis (FHA) can present a consistent technical basis that streamlines implementation. If not coordinated, the DSA and FHA can present inconsistent conclusions, which can create unnecessary confusion and can promulgate a negative safety perception. This paper will compare the scope, purpose, and analysis techniques for DSAs and FHAs. It will also consolidate several lessons-learned papers on this topic, which were prepared in the 1990s.

  13. TRIAGE DOSE ASSESSMENT FOR PARTIAL-BODY EXPOSURE: DICENTRIC ANALYSIS

    PubMed Central

    Moroni, Maria; Pellmar, Terry C.

    2009-01-01

    Partial-body biodosimetry is likely to be required after a radiological or nuclear exposure. Clinical signs and symptoms, distribution of dicentrics in circulating blood cells, organ-specific biomarkers, physical signals in teeth and nails all can provide indications of non-homogeneous exposures. Organ specific biomarkers may provide early warning regarding physiological systems at risk after radiation injury. Use of a combination of markers and symptoms will be needed for clinical insights for therapeutic approaches. Analysis of dicentrics, a marker specific for radiation injury, is the “Gold standard” of biodosimetry and can reveal partial-body exposures. Automation of sample processing for dicentric analysis can increase throughput with customization of off-the-shelf technologies for cytogenetic sample processing and information management. Automated analysis of the metaphase spreads is currently limited but improvements are in development. Our efforts bridge the technological gaps to allow the use of dicentric chromosome assay (DCA) for risk-based stratification of mass casualties. This article summarizes current knowledge on partial-body cytogenetic dose assessment synthesizing information leading to the proposal of an approach to triage dose prediction in radiation mass casualties, based on equivalent whole-body doses under partial-body exposure conditions and assesses the validity of using this model. An initial screening using only 20 metaphase spreads per subject can confirm irradiation above 2-Gy. A subsequent increase to 50 metaphases improves dose determination to allow risk stratification for clinical triage. Metaphases evaluated for inhomogeneous distribution of dicentrics can reveal partial-body exposures. We tested the validity of this approach in an in vitro model that simulates partial-body irradiation by mixing irradiated and un-irradiated lymphocytes in various proportions. Our preliminary results support the notion that this approach will be effective under a range of conditions including some partial-body exposures, but may have limitations with low doses or small proportions of irradiated body. Our studies address an important problem in the diagnosis of partial-body irradiation and dose assessment in mass casualties and propose a solution. However, additional work is needed to fully develop and validate the application of DCA to partial-body exposures. PMID:20065689

  14. 49 CFR 229.307 - Safety analysis.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...railroad shall develop a Safety Analysis (SA) for each product subject to this subpart...product on their railroad. (b) The SA shall: (1) establish and document...c) Each railroad shall comply with the SA requirements and procedures related to...

  15. 49 CFR 229.307 - Safety analysis.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...railroad shall develop a Safety Analysis (SA) for each product subject to this subpart...product on their railroad. (b) The SA shall: (1) establish and document...c) Each railroad shall comply with the SA requirements and procedures related to...

  16. 49 CFR 229.307 - Safety analysis.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...railroad shall develop a Safety Analysis (SA) for each product subject to this subpart...product on their railroad. (b) The SA shall: (1) establish and document...c) Each railroad shall comply with the SA requirements and procedures related to...

  17. Partial correlation analysis for the identification of synaptic connections.

    PubMed

    Eichler, Michael; Dahlhaus, Rainer; Sandkühler, Jürgen

    2003-10-01

    In this paper, we investigate the use of partial correlation analysis for the identification of functional neural connectivity from simultaneously recorded neural spike trains. Partial correlation analysis allows one to distinguish between direct and indirect connectivities by removing the portion of the relationship between two neural spike trains that can be attributed to linear relationships with recorded spike trains from other neurons. As an alternative to the common frequency domain approach based on the partial spectral coherence we propose a new statistic in the time domain. The new scaled partial covariance density provides additional information on the direction and the type, excitatory or inhibitory, of the connectivities. In simulation studies, we investigated the power and limitations of the new statistic. The simulations show that the detectability of various connectivity patterns depends on various parameters such as connectivity strength and background activity. In particular, the detectability decreases with the number of neurons included in the analysis and increases with the recording time. Further, we show that the method can also be used to detect multiple direct connectivities between two neurons. Finally, the methods of this paper are illustrated by an application to neurophysiological data from spinal dorsal horn neurons. PMID:14605893

  18. Uncertainty analysis for Ulysses safety evaluation report

    SciTech Connect

    Frank, M.V. (Safety Factor Associates, 1410 Vanessa Circle, Encinitas, California 92024 (US))

    1991-01-01

    As part of the effort to review the Ulysses Final Safety Analysis Report and to understand the risk of plutonium release from the Ulysses spacecraft General Purpose Heat Source---Radioisotope Thermal Generator (GPHS-RTG), the Interagency Nuclear Safety Review Panel (INSRP) and the author performed an integrated, quantitative analysis of the uncertainties of the calculated risk of plutonium release from Ulysses. Using state-of-art probabilistic risk assessment technology, the uncertainty analysis accounted for both variability and uncertainty of the key parameters of the risk analysis. The results show that INSRP had high confidence that risk of fatal cancers from potential plutonium release associated with calculated launch and deployment accident scenarios is low.

  19. Gas turbine safety improvement through risk analysis

    SciTech Connect

    Crosby, T.M.; Reinman, G.L.

    1987-01-01

    This paper provides certain statistical methods that are used to improve system safety. It provides an understanding of Weibull analysis, in that it describes when the Weibull distribution is appropriate, how to construct a Weibull plot, and how to use the parameters of the Weibull distribution to calculate risk. This paper also provides the engineer with a comprehension of Monte Carlo simulation as it relates to quantifying safety risk. The basic components of Monte Carlo simulation are discussed as well as the formulation of a system model and its application in the gas turbine industry.

  20. Gas turbine safety improvement through risk analysis

    SciTech Connect

    Crosby, T.M.; Reinman, G.L.

    1988-04-01

    This paper is intended to provide the engineer with the information necessary to understand certain statistical methods that are used to improve system safety. It will provide an understanding of Weibull analysis, in that it describes when the Weibull distribution is appropriate, how to construct a Weibull plot, and how to use the parameters of the Weibull distribution to calculate risk. The paper will also provide the engineer with a comprehension of Monte Carlo simulation as it relates to quantifying safety risk. The basic components of Monte Carlo simulation are discussed as well as the formulation of a system model and its application in the gas turbine industry.

  1. Safety analysis review terms of reference

    SciTech Connect

    Hurley, T.

    1981-03-01

    This document has been prepared to suggest procedures and items for consideration in the review of safety analysis prepared on DOE fossil energy conversion and technology development projects. It is not intended to reflect official DOE policy. It does, however, provide a basis for consistency in conducting reviews, especially with regard to interpreting levels of risk. Since many of the persons assigned to review panels are not expected to be safety analysts but specialists in related fields such as industrial hygiene and environmental science, this document is intended to provide general terms of reference to facilitate review procedures.

  2. An intelligent hybrid system for surface coal mine safety analysis

    Microsoft Academic Search

    N. Lilic; I. Obradovic; A. Cvjetic

    2010-01-01

    Analysis of safety in surface coal mines represents a very complex process. Published studies on mine safety analysis are usually based on research related to accidents statistics and hazard identification with risk assessment within the mining industry. Discussion in this paper is focused on the application of AI methods in the analysis of safety in mining environment. Complexity of the

  3. Safety of GM crops: compositional analysis.

    PubMed

    Brune, Philip D; Culler, Angela Hendrickson; Ridley, William P; Walker, Kate

    2013-09-01

    The compositional analysis of genetically modified (GM) crops has continued to be an important part of the overall evaluation in the safety assessment program for these materials. The variety and complexity of genetically engineered traits and modes of action that will be used in GM crops in the near future, as well as our expanded knowledge of compositional variability and factors that can affect composition, raise questions about compositional analysis and how it should be applied to evaluate the safety of traits. The International Life Sciences Institute (ILSI), a nonprofit foundation whose mission is to provide science that improves public health and well-being by fostering collaboration among experts from academia, government, and industry, convened a workshop in September 2012 to examine these and related questions, and a series of papers has been assembled to describe the outcomes of that meeting. PMID:24266762

  4. Safety analysis report for packaging upgrade plan

    SciTech Connect

    Kelly, D.L., Westinghouse Hanford

    1996-12-09

    This Safety Analysis Report for Packaging (SARP) Upgrade Plan reflects a SARP upgrade schedule based on the most current program needs. A performance agreement has been assigned, beginning in FY 1997, to update, revise, and/or cancel 20 percent of the existing onsite SARPS, so that 100 percent are reviewed and within current standards by the completion of the Project Hanford Management Contract (five-year period).

  5. IEEE TRANSACTIONS ON INDUSTRY APPLICATIONS, VOL. 40, NO. 6, NOVEMBER/DECEMBER 2004 1579 Statistical Pattern Analysis of Partial Discharge

    E-print Network

    Yazici, Birsen

    Pattern Analysis of Partial Discharge Measurements for Quality Assessment of Insulation Systems in High analysis method of phase-resolved partial discharge (PD) measurements for the quality assessment) analysis, quality assessment. I. INTRODUCTION PARTIAL discharge (PD) analysis has been established

  6. Safety and tolerability of different titration rates of retigabine (ezogabine) in patients with partial-onset seizures.

    PubMed

    Biton, Victor; Gil-Nagel, Antonio; Brodie, Martin J; Derossett, Sarah E; Nohria, Virinder

    2013-11-01

    Retigabine (RTG; international nonproprietary name)/ezogabine (EZG; US adopted name) is an antiepileptic drug (AED) that prolongs neuronal voltage-gated potassium-channel KCNQ2-5 (Kv 7.2-7.5) opening. This double-blind study evaluated different RTG/EZG dose-titration rates. Patients (N=73) with partial-onset seizures receiving concomitant AEDs were randomized to one of three titration groups, all of which were initiated at RTG/EZG 300mg/day divided into three equal doses. Fast-, medium-, and slow-titration groups received dose increments of 150mg/day every 2, 4, and 7 days, respectively, achieving the target dose of 1200mg/day after 13, 25, and 43 days, respectively. Safety assessments were performed throughout. Discontinuation rates due to treatment-emergent adverse events (TEAEs) were numerically higher in the fast- (10/23) and medium- (7/22) titration groups than in the slow-titration group (3/23) but statistical significance was achieved only for the high-titration group compared with the low-titration group (p=0.024). Stratified analysis, with concomitant AEDs divided into enzyme inducers (carbamazepine, phenytoin, oxcarbazepine) or noninducers, showed that the risk of discontinuation due primarily to TEAEs was significantly higher in the fast- (p=0.010) but not in the medium-titration group (p=0.078) when compared with the slow-titration group. Overall, the slow-titration rate appeared to be best tolerated and was used in further efficacy and safety studies with RTG/EZG. PMID:24094693

  7. Empirical Analysis of Safety-Critical Anomalies During Operations

    E-print Network

    Lutz, Robyn R.

    safety, diagnostics, maintenance process, product metrics. æ 1 INTRODUCTION THE effort to build safeEmpirical Analysis of Safety-Critical Anomalies During Operations Robyn R. Lutz, Member, IEEE little research on anomaly analysis of safety-critical systems. In particular, patterns of software

  8. Partial least squares-based gene expression analysis in preeclampsia.

    PubMed

    Jiang, F; Yang, Y; Li, J; Li, W; Luo, Y; Li, Y; Zhao, H; Wang, X; Yin, G; Wu, G

    2015-01-01

    Preeclampsia is major cause of maternal and fetal morbidity and mortality. Currently, the etiology of preeclampsia is unclear. In this study, we investigated differences in gene expression between preeclampsia patients and controls using partial least squares-based analysis, which is more suitable than routine analysis. Expression profile data were downloaded from the Gene Expression Omnibus database. A total of 503 genes were found to be differentially expressed, including 248 downregulated genes and 255 overexpressed genes. Network analysis identified 5 hub genes, including UBB, PIK3R1, MAPRE1, VEGFA, and ITGB1. Three of these, PIK3R1, VEGFA, and ITGB1, are known to be associated with preeclampsia or preeclampsia-related biological processes. Our findings shed light on expression signatures of preeclampsia patients that can be used as theoretical support in future therapeutic studies. PMID:26125867

  9. Formal Safety Analysis of Transportation Control Frank Ortmeier, Wolfgang Reif

    E-print Network

    Reif, Wolfgang

    are a great help. The ForMoSA approach provides an integrated methodology for formally ana­ lyzing safety. In the following we will briefly describe the ForMoSA approach to safety analysis of critical, embedded system

  10. Rankine bottoming cycle safety analysis. Final report

    SciTech Connect

    Lewandowski, G.A.

    1980-02-01

    Vector Engineering Inc. conducted a safety and hazards analysis of three Rankine Bottoming Cycle Systems in public utility applications: a Thermo Electron system using Fluorinal-85 (a mixture of 85 mole % trifluoroethanol and 15 mole % water) as the working fluid; a Sundstrand system using toluene as the working fluid; and a Mechanical Technology system using steam and Freon-II as the working fluids. The properties of the working fluids considered are flammability, toxicity, and degradation, and the risks to both plant workers and the community at large are analyzed.

  11. Safety analysis report for packaging upgrade plan

    SciTech Connect

    KELLY, D.L.

    1998-11-18

    This Safety Analysis Report for Packaging (SARP) Upgrade Plan reflects a revised SARP upgrade schedule based on the most current program needs. A Project Hanford Management Contract (PHMC) Performance Expectation exists to update, revise, and/or cancel seven onsite SARPS during FY 1999. It is the U.S. Department of Energy's desire that 100% of the SARPs (which existed at the beginning of the PHMC Contract) be upgraded, revised, and/or canceled by the end of the five year contract. This plan is a ''living'' document and is used as a management tool.

  12. Quantum scattering problem without partial-wave analysis

    NASA Astrophysics Data System (ADS)

    Melezhik, V. S.

    2013-02-01

    We have suggested a method for treating different quantum few-body dynamics without traditional using of the partial-wave analysis. It happened that this approach was very efficient in quantitative analysis of low-dimensional ultracold few-body systems arising in confined geometry of atomic traps. Here we discuss its application to a recently suggested mechanism of resonant molecule formation in confined two-component atomic mixture with transferring the energy release to the center-of-mass excitation of forming molecules. The author considers this result as one of the most significant in his scientific carrier which started from the model of resonant muonic molecule formation [S.I. Vinitsky et al., Sov. Phys. JETP 47, 444 (1978)], one of the most citing works of S.I. Vinitsky.

  13. 242-A evaporator safety analysis report

    SciTech Connect

    CAMPBELL, T.A.

    1999-05-17

    This report provides a revised safety analysis for the upgraded 242-A Evaporator (the Evaporator). This safety analysis report (SAR) supports the operation of the Evaporator following life extension upgrades and other facility and operations upgrades (e.g., Project B-534) that were undertaken to enhance the capabilities of the Evaporator. The Evaporator has been classified as a moderate-hazard facility (Johnson 1990). The information contained in this SAR is based on information provided by 242-A Evaporator Operations, Westinghouse Hanford Company, site maintenance and operations contractor from June 1987 to October 1996, and the existing operating contractor, Waste Management Hanford (WMH) policies. Where appropriate, a discussion address the US Department of Energy (DOE) Orders applicable to a topic is provided. Operation of the facility will be compared to the operating contractor procedures using appropriate audits and appraisals. The following subsections provide introductory and background information, including a general description of the Evaporator facility and process, a description of the scope of this SAR revision,a nd a description of the basic changes made to the original SAR.

  14. Online E#cient Predictive Safety Analysis of Multithreaded Programs

    E-print Network

    Sen, Koushik

    safety formal specification, the program is automatically instrumented to emit relevant state update, such as model checking and theorem proving, guaranteeing that a formal model of the system satisfies its safety for safety analysis of multithreaded systems, that can be tuned to analyze from one trace to all traces

  15. Online Efficient Predictive Safety Analysis of Multithreaded Programs

    E-print Network

    Sen, Koushik

    safety formal specification, the program is automatically instrumented to emit relevant state update, such as model checking and theorem proving, guaranteeing that a formal model of the system satisfies its safety for safety analysis of multithreaded systems, that can be tuned to analyze from one trace to all traces

  16. Mining equipment safety: a review, analysis methods and improvement strategies

    Microsoft Academic Search

    Balbir S. Dhillon

    2009-01-01

    This article presents facts and figures on mining equipment safety and reviews various important aspects of mining equipment safety including quarry accidents, electrical accidents, equipment fires, maintenance-related mining accidents, causes of mining equipment accidents and major ignition sources for mining equipment fires. A number of methods considered useful for performing mining equipment safety analysis are also presented. Useful strategies to

  17. Safety and capacity analysis of automated and manual highway systems

    E-print Network

    Sengupta, Raja

    Safety and capacity analysis of automated and manual highway systems Jason Carbaugh, Datta N Abstract This paper compares safety of automated and manual highway systems with respect to resulting rear-end collision frequency and severity. Safety is related to driver, vehicle and highway operating characteristics

  18. Adjoint sensitivity analysis for time-dependent partial differential equations with adaptive mesh refinement q

    E-print Network

    Petzold, Linda R.

    Adjoint sensitivity analysis for time-dependent partial differential equations with adaptive mesh-dependent partial differential equations with adaptive mesh refinement. The new approach, called ADDA, combines equations; Adjoint PDE; Discrete approach; Continuous approach; Adaptive mesh method 1. Introduction

  19. Issues affecting advanced passive light-water reactor safety analysis

    SciTech Connect

    Beelman, R.J.; Fletcher, C.D.; Modro, S.M.

    1992-01-01

    Next generation commercial reactor designs emphasize enhanced safety through improved safety system reliability and performance by means of system simplification and reliance on immutable natural forces for system operation. Simulating the performance of these safety systems will be central to analytical safety evaluation of advanced passive reactor designs. Yet the characteristically small driving forces of these safety systems pose challenging computational problems to current thermal-hydraulic systems analysis codes. Additionally, the safety systems generally interact closely with one another, requiring accurate, integrated simulation of the nuclear steam supply system, engineered safeguards and containment. Furthermore, numerical safety analysis of these advanced passive reactor designs wig necessitate simulation of long-duration, slowly-developing transients compared with current reactor designs. The composite effects of small computational inaccuracies on induced system interactions and perturbations over long periods may well lead to predicted results which are significantly different than would otherwise be expected or might actually occur. Comparisons between the engineered safety features of competing US advanced light water reactor designs and analogous present day reactor designs are examined relative to the adequacy of existing thermal-hydraulic safety codes in predicting the mechanisms of passive safety. Areas where existing codes might require modification, extension or assessment relative to passive safety designs are identified. Conclusions concerning the applicability of these codes to advanced passive light water reactor safety analysis are presented.

  20. Issues affecting advanced passive light-water reactor safety analysis

    SciTech Connect

    Beelman, R.J.; Fletcher, C.D.; Modro, S.M.

    1992-08-01

    Next generation commercial reactor designs emphasize enhanced safety through improved safety system reliability and performance by means of system simplification and reliance on immutable natural forces for system operation. Simulating the performance of these safety systems will be central to analytical safety evaluation of advanced passive reactor designs. Yet the characteristically small driving forces of these safety systems pose challenging computational problems to current thermal-hydraulic systems analysis codes. Additionally, the safety systems generally interact closely with one another, requiring accurate, integrated simulation of the nuclear steam supply system, engineered safeguards and containment. Furthermore, numerical safety analysis of these advanced passive reactor designs wig necessitate simulation of long-duration, slowly-developing transients compared with current reactor designs. The composite effects of small computational inaccuracies on induced system interactions and perturbations over long periods may well lead to predicted results which are significantly different than would otherwise be expected or might actually occur. Comparisons between the engineered safety features of competing US advanced light water reactor designs and analogous present day reactor designs are examined relative to the adequacy of existing thermal-hydraulic safety codes in predicting the mechanisms of passive safety. Areas where existing codes might require modification, extension or assessment relative to passive safety designs are identified. Conclusions concerning the applicability of these codes to advanced passive light water reactor safety analysis are presented.

  1. Safety and efficacy of levetiracetam for the treatment of partial onset seizures in children from one month of age

    PubMed Central

    Cormier, Justine; Chu, Catherine J

    2013-01-01

    Epilepsy is a common neurological disorder in the pediatric population, affecting up to one percent of children, and for which the mainstay of treatment is anticonvulsant medication. Despite the frequent use of anticonvulsant drugs, remarkably little is known about the safety and efficacy of most of these medications in the pediatric epilepsy population. Of 34 anticonvulsants currently approved for use by the US Food and Drug Administration (FDA), only 13 have been approved for use in children. Although infants and young children are disproportionately affected by epilepsy, there are currently only three anticonvulsant medications that have been specifically evaluated and approved for use in children younger than 2 years of age. In 2012, the FDA approved levetiracetam as an adjunctive treatment for partial onset seizures in infants and children from one month of age. Here we review the available data on levetiracetam in the pediatric epilepsy population. We first discuss the pharmacological profile of levetiracetam, including its mechanism of action, formulations and dosing, and pharmacokinetics in children. We then review the available efficacy, safety, and tolerability data in children from one month of age with partial onset seizures. We conclude that the current data leading to the approval of levetiracetam for use in infants and children with partial onset seizures is encouraging, although more work needs to be done before definitive conclusions can be drawn about the efficacy of levetiracetam across different pediatric age groups. PMID:23458993

  2. Modeling Controller Tasks for Safety Analysis

    NASA Technical Reports Server (NTRS)

    Brown, Molly; Leveson, Nancy G.

    1998-01-01

    As control systems become more complex, the use of automated control has increased. At the same time, the role of the human operator has changed from primary system controller to supervisor or monitor. Safe design of the human computer interaction becomes more difficult. In this paper, we present a visual task modeling language that can be used by system designers to model human-computer interactions. The visual models can be translated into SpecTRM-RL, a blackbox specification language for modeling the automated portion of the control system. The SpecTRM-RL suite of analysis tools allow the designer to perform formal and informal safety analyses on the task model in isolation or integrated with the rest of the modeled system.

  3. Using Crash Costs in Safety Analysis

    Microsoft Academic Search

    Paul F Hanley

    2004-01-01

    There are three primary reasons DOTs invest in road and highway upgrades—to promote economic development, to alleviate congestion, and to improve safety. This monograph focuses on the third of these. Funds for safety improvements are always limited, and projects must be carefully selected to maximize the net safety improvement to society. Forkenbrock, et al. (1994) proposed a methodology for estimating

  4. ASIAS: Aviation Safety Information Analysis and sharing

    Microsoft Academic Search

    C. Halford; M. Harper

    2008-01-01

    In the past decade the concept of establishing a nationwide safety information sharing initiative has grown from a dream into reality. From roots dating back to the TWA 514 NTSB report in 1974, it has become increasingly clear that safety data sharing is a necessary component of the overall plan to manage safety at the national level. Building from these

  5. Final report for confinement vessel analysis. Task 2, Safety vessel impact analyses

    SciTech Connect

    Murray, Y.D. [APTEK, Inc., Colorado Springs, CO (United States)

    1994-01-26

    This report describes two sets of finite element analyses performed under Task 2 of the Confinement Vessel Analysis Program. In each set of analyses, a charge is assumed to have detonated inside the confinement vessel, causing the confinement vessel to fail in either of two ways; locally around the weld line of a nozzle, or catastrophically into two hemispheres. High pressure gases from the internal detonation pressurize the inside of the safety vessel and accelerate the fractured nozzle or hemisphere into the safety vessel. The first set of analyses examines the structural integrity of the safety vessel when impacted by the fractured nozzle. The objective of these calculations is to determine if the high strength bolt heads attached to the nozzle penetrate or fracture the lower strength safety vessel, thus allowing gaseous detonation products to escape to the atmosphere. The two dimensional analyses predict partial penetration of the safety vessel beneath the tip of the penetrator. The analyses also predict maximum principal strains in the safety vessel which exceed the measured ultimate strain of steel. The second set of analyses examines the containment capability of the safety vessel closure when impacted by half a confinement vessel (hemisphere). The predicted response is the formation of a 0.6-inch gap, caused by relative sliding and separation between the two halves of the safety vessel. Additional analyses with closure designs that prevent the gap formation are recommended.

  6. Evolutionary Safety Analysis: Motivations from the Air Traffic Management Domain

    E-print Network

    Felici, Massimo

    Evolutionary Safety Analysis: Motivations from the Air Traffic Management Domain Massimo Felici-Verlag Berlin Heidelberg 2005 #12;Evolutionary Safety Analysis 209 traffic demand as well as the operational the ATM (Air Traffic Management) 2000+ Strategy, systems from different suppli- ers will be interconnected

  7. Safety analysis of the nuclear chemistry Building 151

    SciTech Connect

    Kvam, D.

    1984-06-29

    This report summarizes the results of a safety analysis that was done on Building 151. The report outlines the methodology, the analysis, and the findings that led to the low hazard classification. No further safety evaluation is indicated at this time. 5 tables.

  8. Cost Benefit Analysis of Consumer Product Safety Standards

    ERIC Educational Resources Information Center

    Smith, Betty F.; Dardis, Rachel

    1977-01-01

    This paper investigates the role of cost-benefit analysis in evaluating consumer product safety standards and applys such analysis to an evaluation of flammability standards for children's sleepwear. (Editor)

  9. Aggregate nonparametric safety analysis of traffic zones.

    PubMed

    Siddiqui, Chowdhury; Abdel-Aty, Mohamed; Huang, Helai

    2012-03-01

    Exploring the significant variables related to specific types of crashes is vitally important in the planning stage of a transportation network. This paper aims to identify and examine important variables associated with total crashes and severe crashes per traffic analysis zone (TAZ) in four counties of the state of Florida by applying nonparametric statistical techniques such as data mining and random forest. The intention of investigating these factors in such aggregate level analysis is to incorporate proactive safety measures in transportation planning. Total and severe crashes per TAZ were modeled to provide predictive decision trees. The variables which carried higher weight of importance for total crashes per TAZ were - total number of intersections per TAZ, airport trip productions, light truck productions, and total roadway segment length with 35 mph posted speed limit. The other significant variables identified for total crashes were total roadway length with 15 mph posted speed limit, total roadway length with 65 mph posted speed limit, and non-home based work productions. For severe crashes, total number of intersections per TAZ, light truck productions, total roadway length with 35 mph posted speed limit, and total roadway length with 65 mph posted speed limit were among the significant variables. These variables were further verified and supported by the random forest results. PMID:22269515

  10. TA-55 Final Safety Analysis Report Comparison Document and DOE Safety Evaluation Report Requirements

    SciTech Connect

    Alan Bond

    2001-04-01

    This document provides an overview of changes to the currently approved TA-55 Final Safety Analysis Report (FSAR) that are included in the upgraded FSAR. The DOE Safety Evaluation Report (SER) requirements that are incorporated into the upgraded FSAR are briefly discussed to provide the starting point in the FSAR with respect to the SER requirements.

  11. Analysis of abutment teeth in partially edentulous patients.

    PubMed

    Stanci?, Ivica; Popovac, Aleksandra; Rodi?, Teodora; Stipeti?, Jasmina; Strajni?, Ljiljana; Persi?, Sanja

    2014-06-01

    The aim of the study was to examine changes in the position of the abutment teeth (AT), size of undercuts for a denture clasp, as well as an existence of an adequate preparation of abutment teeth. A total of 156 casts of partially edentulous jaws, with 460 AT, were analyzed. The size of undercuts, a degree of abutment rotation, inclination and migration were measured using a dental parallelometer. The abutment teeth position was related to the level of occlusal plane in a dental articulator. Furthermore, the existence of an adequate preparation of abutment teeth, as well as a type of a denture and a type of a denture retention element were also considered. Analysis were carried out twice on casts made from a hard stone, the first time before the denture treatment had begun and the second time on the new casts obtained after new dentures had been delivered. The first analysis (prior dental treatment) revealed that a total of 33.9% of the analyzed AT were rotated, 31.3% were inclined, 12.1% had migrated, and 57.3% were elongated above the occlusal plane. On the casts obtained after the new dentures had been made, it was observed that none of the AT had an adequate preparation. Only 37.6% of all retention elements were located in adequate undercut positions on the AT. Upon the results of the present study a conclusion can be established that many abutment teeth are rotated, elongated, inclined, and migrated, which point to a requirement for AT preparation prior the manufacture of new denture; however none of the AT was adequately prepared considering insertion plane and many denture elements were located in an inadequate undercut size. PMID:25145006

  12. Analysis of partial and complete protection in malaria cohort studies

    PubMed Central

    2013-01-01

    Background Malaria transmission is highly heterogeneous and analysis of incidence data must account for this for correct statistical inference. Less widely appreciated is the occurrence of a large number of zero counts (children without a malaria episode) in malaria cohort studies. Zero-inflated regression methods provide one means of addressing this issue, and also allow risk factors providing complete and partial protection to be disentangled. Methods Poisson, negative binomial (NB), zero-inflated Poisson (ZIP) and zero-inflated negative binomial (ZINB) regression models were fitted to data from two cohort studies of malaria in children in Ghana. Multivariate models were used to understand risk factors for elevated incidence of malaria and for remaining malaria-free, and to estimate the fraction of the population not at risk of malaria. Results ZINB models, which account for both heterogeneity in individual risk and an unexposed sub-group within the population, provided the best fit to data in both cohorts. These approaches gave additional insight into the mechanism of factors influencing the incidence of malaria compared to simpler approaches, such as NB regression. For example, compared to urban areas, rural residence was found to both increase the incidence rate of malaria among exposed children, and increase the probability of being exposed. In Navrongo, 34% of urban residents were estimated to be at no risk, compared to 3% of rural residents. In Kintampo, 47% of urban residents and 13% of rural residents were estimated to be at no risk. Conclusion These results illustrate the utility of zero-inflated regression methods for analysis of malaria cohort data that include a large number of zero counts. Specifically, these results suggest that interventions that reach mainly urban residents will have limited overall impact, since some urban residents are essentially at no risk, even in areas of high endemicity, such as in Ghana. PMID:24093726

  13. Partial discharge detection and analysis in low pressure environments

    NASA Astrophysics Data System (ADS)

    Liu, Xin

    Typical aerospace vehicles (aircraft and spacecraft) experience a wide range of operating pressures during ascending and returning to earth. Compared to the sea-level atmospheric pressure (760 Torr), the pressure at about 60 km altitude is 2 Torr. The performance of the electric power system components of the aerospace vehicles must remain reliable even under such sub-atmospheric operating conditions. It is well known that the dielectric strength of gaseous insulators, while the electrode arrangement remains unchanged, is pressure dependent. Therefore, characterization of the performance and behavior of the electrical insulation in flight vehicles in low-pressure environments is extremely important. Partial discharge testing is one of the practical methods for evaluating the integrity of electrical insulation in aerospace vehicles. This dissertation describes partial discharge (PD) measurements performed mainly with 60 Hz ac energization in air, argon and helium, for pressures between 2 and 760 Torr. Two main electrode arrangements were used. One was a needle-plane electrode arrangement with a Teflon insulating barrier. The other one was a twisted pair of insulated conductors taken from a standard aircraft wiring harness. The measurement results are presented in terms of typical PD current pulse waveforms and waveform analysis for both main electrode arrangements. The evaluation criteria are the waveform polarity, magnitude, shape, rise time, and phase angle (temporal location) relative to the source voltage. Two-variable histograms and statistical averages of the PD parameters are presented. The PD physical mechanisms are analyzed. For PD pattern recognition, both statistical methods (such as discharge parameter dot pattern representation, discharge parameter phase distribution, statistical operator calculations, and PD fingerprint development) and wavelet transform applications are investigated. The main conclusions of the dissertation include: (1) The PD current pulse waveforms are dependent on the pressure. (2) The rise time of the waveform is another effective PD current pulse characteristic indicator. (3) PD fingerprint patterns that are already available for atmospheric pressure (760 Torr) conditions are inadequate for the evaluation of PD pulses at low pressures. (4) Various wavelet transform techniques can be used effectively for PD pulse signal denoising purposes, and for PD pulse waveform transient feature recognition.

  14. 78 FR 4477 - Review of Safety Analysis Reports for Nuclear Power Plants, Introduction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ...of Safety Analysis Reports for Nuclear Power Plants, Introduction AGENCY...of Safety Analysis Reports for Nuclear Power Plants: LWR Edition.'' The...of Safety Analysis Reports for Nuclear Power Plants: Integral...

  15. Partial differential equation transform — Variational formulation and Fourier analysis

    PubMed Central

    Wang, Yang; Wei, Guo-Wei; Yang, Siyang

    2011-01-01

    Nonlinear partial differential equation (PDE) models are established approaches for image/signal processing, data analysis and surface construction. Most previous geometric PDEs are utilized as low-pass filters which give rise to image trend information. In an earlier work, we introduced mode decomposition evolution equations (MoDEEs), which behave like high-pass filters and are able to systematically provide intrinsic mode functions (IMFs) of signals and images. Due to their tunable time-frequency localization and perfect reconstruction, the operation of MoDEEs is called a PDE transform. By appropriate selection of PDE transform parameters, we can tune IMFs into trends, edges, textures, noise etc., which can be further utilized in the secondary processing for various purposes. This work introduces the variational formulation, performs the Fourier analysis, and conducts biomedical and biological applications of the proposed PDE transform. The variational formulation offers an algorithm to incorporate two image functions and two sets of low-pass PDE operators in the total energy functional. Two low-pass PDE operators have different signs, leading to energy disparity, while a coupling term, acting as a relative fidelity of two image functions, is introduced to reduce the disparity of two energy components. We construct variational PDE transforms by using Euler-Lagrange equation and artificial time propagation. Fourier analysis of a simplified PDE transform is presented to shed light on the filter properties of high order PDE transforms. Such an analysis also offers insight on the parameter selection of the PDE transform. The proposed PDE transform algorithm is validated by numerous benchmark tests. In one selected challenging example, we illustrate the ability of PDE transform to separate two adjacent frequencies of sin(x) and sin(1.1x). Such an ability is due to PDE transform’s controllable frequency localization obtained by adjusting the order of PDEs. The frequency selection is achieved either by diffusion coefficients or by propagation time. Finally, we explore a large number of practical applications to further demonstrate the utility of proposed PDE transform. PMID:22207904

  16. SNF fuel retrieval sub project safety analysis document

    SciTech Connect

    BERGMANN, D.W.

    1999-02-24

    This safety analysis is for the SNF Fuel Retrieval (FRS) Sub Project. The FRS equipment will be added to K West and K East Basins to facilitate retrieval, cleaning and repackaging the spent nuclear fuel into Multi-Canister Overpack baskets. The document includes a hazard evaluation, identifies bounding accidents, documents analyses of the accidents and establishes safety class or safety significant equipment to mitigate accidents as needed.

  17. Analysis of microgravity space experiments Space Shuttle programmatic safety requirements

    NASA Technical Reports Server (NTRS)

    Terlep, Judith A.

    1996-01-01

    This report documents the results of an analysis of microgravity space experiments space shuttle programmatic safety requirements and recommends the creation of a Safety Compliance Data Package (SCDP) Template for both flight and ground processes. These templates detail the programmatic requirements necessary to produce a complete SCDP. The templates were developed from various NASA centers' requirement documents, previously written guidelines on safety data packages, and from personal experiences. The templates are included in the back as part of this report.

  18. Creating Aviation Safety Dictionary through Analysis

    Microsoft Academic Search

    Wang Hongwei; Feng Xia; Huan Xiuxia

    2008-01-01

    Since the aviation safety information contains both structured and textual data, this paper proposed a strategy for creating aviation safety dictionary. It used the maximum match algorithm based on segmentation unit to obtain the candidate word set and adopted the mutually information to improve the word extraction accuracy in cooperation with domain specialists. Experiments showed that the created dictionary could

  19. Job Safety Analysis (JSA) College of Engineering

    E-print Network

    Saskatchewan, University of

    . Saskatchewan Occupational Health and Safety Act 2. Saskatchewan Occupational Health and Safety Regulations 3) periodically to reduce stress on the spine · Take regularly scheduled breaks See Office Ergonomics Self Help · Contact stress · Repetitive activities · Adjust keyboard tray. Refer to Office Ergonomics Self Help Manual

  20. Moon manned missions radiation safety analysis

    NASA Astrophysics Data System (ADS)

    Tripathi, R. K.; Wilson, J. W.; de Anlelis, G.; Badavi, F. F.

    An analysis is performed on the radiation environment found on the surface of the Moon, and applied to different possible lunar base mission scenarios. An optimization technique has been used to obtain mission scenarios minimizing the astronaut radiation exposure and at the same time controlling the effect of shielding, in terms of mass addition and material choice, as a mission cost driver. The optimization process has been realized through minimization of mass along all phases of a mission scenario, in terms of time frame (dates, transfer time length and trajectory, radiation environment), equipment (vehicles, in terms of shape, volume, onboard material choice, size and structure), location (if in space, on the surface, inside or outside a certain habitats), crew characteristics (number, gender, age, tasks) and performance required (spacecraft and habitat volumes), radiation exposure annual and career limit constraint (from NCRP 132), and implementation of the ALARA principle (shelter from the occurrence of Solar Particle Events). On the lunar surface the most important contribution to radiation exposure is given by background Galactic Cosmic Rays (GCR) particles, mostly protons, alpha particles, and some heavy ions, and by locally induced particles, mostly neutrons, created by the interaction between GCR and surface material and emerging from below the surface due to backscattering processes. In this environment manned habitats are to host future crews involved in the construction and/or in the utilization of moon based infrastructure. Three different kinds of lunar missions are considered in the analysis, Moon Base Construction Phase, during which astronauts are on the surface just to build an outpost for future resident crews, Moon Base Outpost Phase, during which astronaut crews are resident but continuing exploration and installation activities, and Moon Base Routine Phase, with long-term shifting resident crews. In each scenario various kinds of habitats, from very simple shelters to more complex bases, are considered in full detail (e.g., shape, thickness, materials, etc) with considerations of various shielding strategies. In this first analysis all the shape considered are cylindrical or composed of combination of cylinders. Moreover, a radiation safety analysis of more future possible habitats like lava tubes has been also performed.

  1. Lunar mission safety and rescue: Hazards analysis and safety requirements

    NASA Technical Reports Server (NTRS)

    1971-01-01

    The results are presented of the hazards analysis which was concerned only with hazards to personnel and not with loss of equipment or property. Hazards characterization includes the definition of a hazard, the hazard levels, and the hazard groups. The analysis methodology is described in detail. The methodology was used to prepare the top level functional flow diagrams, to perform the first level hazards assessment, and to develop a list of conditions and situations requiring individual hazard studies. The 39 individual hazard study results are presented in total.

  2. Analysis of Subsea Buried Pipelines and Partially Buried Cables 

    E-print Network

    Bai, Yanbin

    2014-08-26

    pipe wall temperature, and the importance of pipeline burial depth on seabed temperature distribution above the pipeline. In order to better address the problem of partially buried subsea cables, a three dimensional meshfree method was formulated...

  3. Systems Analysis of NASA Aviation Safety Program: Final Report

    NASA Technical Reports Server (NTRS)

    Jones, Sharon M.; Reveley, Mary S.; Withrow, Colleen A.; Evans, Joni K.; Barr, Lawrence; Leone, Karen

    2013-01-01

    A three-month study (February to April 2010) of the NASA Aviation Safety (AvSafe) program was conducted. This study comprised three components: (1) a statistical analysis of currently available civilian subsonic aircraft data from the National Transportation Safety Board (NTSB), the Federal Aviation Administration (FAA), and the Aviation Safety Information Analysis and Sharing (ASIAS) system to identify any significant or overlooked aviation safety issues; (2) a high-level qualitative identification of future safety risks, with an assessment of the potential impact of the NASA AvSafe research on the National Airspace System (NAS) based on these risks; and (3) a detailed, top-down analysis of the NASA AvSafe program using an established and peer-reviewed systems analysis methodology. The statistical analysis identified the top aviation "tall poles" based on NTSB accident and FAA incident data from 1997 to 2006. A separate examination of medical helicopter accidents in the United States was also conducted. Multiple external sources were used to develop a compilation of ten "tall poles" in future safety issues/risks. The top-down analysis of the AvSafe was conducted by using a modification of the Gibson methodology. Of the 17 challenging safety issues that were identified, 11 were directly addressed by the AvSafe program research portfolio.

  4. Genomic analysis of partial 21q monosomies with variable phenotypes

    Microsoft Academic Search

    Elisha D O Roberson; Elizabeth Squibb Wohler; Julie E Hoover-Fong; Emily Lisi; Eric L Stevens; George H Thomas; Jay Leonard; Ada Hamosh; Jonathan Pevsner

    2011-01-01

    Partial monosomy 21 was recently segregated into three regions associated with variable clinical severity. We describe 10 new patients, all examined by single nucleotide polymorphism (SNP) genotyping and G-banded karyotyping. Cohort A consisted of three patients seen in our medical genetics clinics with partial chromosome 21 monosomies. In two of these patients having terminal deletions (21q22.2-ter and 21q22.3-ter), the breakpoints

  5. Bayesian Analysis for Partially Complete Time and Type of Failure Data

    E-print Network

    Kundu, Debasis

    Bayesian Analysis for Partially Complete Time and Type of Failure Data Debasis Kundu Abstract In this paper we consider the Bayesian analysis of competing risks data, when the data are partially complete Weibull distributions with the common shape parameter but different scale parameters. When the shape

  6. Safety analysis of the 700-horsepower combustion test facility

    Microsoft Academic Search

    Berkey

    1981-01-01

    The objective of the program reported herein was to provide a Safety Analysis of the 700 h.p. Combustion Test Facility located in Building 93 at the Pittsburgh Energy Technology Center. Extensive safety related measures have been incorporated into the design, construction, and operation of the Combustion Test Facility. These include: nitrogen addition to the coal storage bin, slurry hopper, roller

  7. Documented safety analysis for 209-E Facility critical mass laboratory

    SciTech Connect

    DODD, E.

    2003-04-23

    This documented safety analysis (DSA) addresses the 209-E facility and associated requirements that apply to 200 Area Facility Deactivation (AFD) activities. The DSA was developed in accordance with DOE-STD-1120-98, ''Integration of Environment, Safety, and Health into Facility Disposition Activities''.

  8. Formal Safety Analysis of Transportation Control Frank Ortmeier, Wolfgang Reif

    E-print Network

    Reif, Wolfgang

    with only minimal risk. To ensure these requirements formal methods are a great help. The ForMoSA approach provides an integrated methodology for formally ana- lyzing safety-critical transportation systems. One describe the ForMoSA approach to safety analysis of critical, embedded system (Sect. 2), outline a possible

  9. Effectiveness, Tolerability, and Safety of Topiramate in Children with Partial-Onset Seizures

    Microsoft Academic Search

    Frank Ritter; Tracy A. Glauser; Roy D. Elterman; Elaine Wyllie

    2000-01-01

    Summary: Purpose: Children with partial-onset seizures, with or without secondary generalization, participating in a double-blind, placebo-controlled trial of topiramate (TPM) as adjunctive therapy were eligible to participate in an open-label, long-term extension study. Methods: A total of 83 children (mean age, 9 years) contin- ued long-term open-label TPM therapy in which the dosages of TPM and concomitant antiepileptic drugs (AEDs)

  10. Safety analysis report 231-Z Building

    SciTech Connect

    Powers, C.S.

    1989-03-01

    This report provides an intensive review of the nuclear safety of the operation of the 231-Z Building. For background information complete descriptions of the floor plan, building services, alarm systems, and glove box systems are included in this report. In addition, references are included to The Plutonium Laboratory Radiation Work Procedures, Safety Guides, 231-Z Operating Procedures Manual and Nuclear Materials accountability Procedures. Engineered and administrative features contribute to the overall safety of personnel, the building, and environs. The consequences of credible incidents were considered and are discussed.

  11. Formal Safety Analysis of Transportation Control Systems

    Microsoft Academic Search

    Frank Ortmeier; Wolfgang Reif

    From a safety point of view different transportation systems share many properties and requirements. They are all supposed to function correctly, to be failure tolerant and to be associated with only minimal risk. To ensure these requirements formal methods are a great help. The ForMoSA approach provides an integrated methodology for formally ana- lyzing safety-critical transportation systems. One important and

  12. 14 CFR 417.213 - Flight safety limits analysis.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...for all times during flight. Flight safety limits must account...a minimum: (1) All time delays, as established by the time delay analysis of § 417.221; ...Residual thrust remaining after flight termination implementation...

  13. 14 CFR 417.213 - Flight safety limits analysis.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...for all times during flight. Flight safety limits must account...a minimum: (1) All time delays, as established by the time delay analysis of § 417.221; ...Residual thrust remaining after flight termination implementation...

  14. Safety-driven early concept analysis and development

    E-print Network

    Fleming, Cody Harrison

    2015-01-01

    As aerospace systems become increasingly complex and the roles of human operators and autonomous software continue to evolve, traditional safety-related analytical methods are becoming inadequate. Traditional hazard analysis ...

  15. Galileo and Ulysses missions safety analysis and launch readiness status

    NASA Technical Reports Server (NTRS)

    Cork, M. Joseph; Turi, James A.

    1989-01-01

    The Galileo spacecraft, which will release probes to explore the Jupiter system, was launched in October, 1989 as the payload on STS-34, and the Ulysses spacecraft, which will fly by Jupiter en route to a polar orbit of the sun, is presently entering system-test activity in preparation for an October, 1990 launch. This paper reviews the Galileo and Ulysses mission objectives and design approaches and presents details of the missions' safety analysis. The processes used to develop the safety analysis are described and the results of safety tests are presented.

  16. Safety and efficacy of TransCyte for the treatment of partial-thickness burns.

    PubMed

    Noordenbos, J; Doré, C; Hansbrough, J F

    1999-01-01

    Standard treatment for extensive partial-thickness burns in the United States and in much of the world involves the application of topical antimicrobial agents and repetitive wound débridements and dressing changes. We evaluated a new biologic wound covering, TransCyte (Advanced Tissue Sciences, La Jolla, Calif, formerly marketed as Dermagraft-Transitional Covering), for the treatment of partial-thickness burns. This material is composed of human newborn fibroblasts which are then cultured on the nylon mesh of Biobrane (Dow B. Hickam, Inc, Sugarland, Tex); the thin silicone membrane bonded to the mesh provides a moisture vapor barrier for the wound. A prospective, randomized, comparison study of silver sulfadiazine and TransCyte was performed with the use of paired wound sites on 14 patients. Wounds treated with TransCyte healed more quickly (mean 11.14 days to 90% epithelialization vs 18.14 days, P = .002). A noncomparison evaluation was then done for an additional 18 patients, and it confirmed excellent wound healing and an absence of infections. There were no infections in the 32 wound sites treated with TransCyte. In the first study group, late wound evaluations (3, 6, and 12 months postburn) were performed with use of the Vancouver Scar Scale. The results indicated that wound sites treated with TransCyte healed with less hypertrophic scarring than sites treated with silver sulfadiazine (P < .001 at 3 and 6 months, P = .006 at 12 months). PMID:10425589

  17. Characterization of wheat-Thinopyrum partial amphiploids by meiotic analysis and genomic in situ hybridization.

    PubMed

    Fedak, G; Chen, Q; Conner, R L; Laroche, A; Petroski, R; Armstrong, K W

    2000-08-01

    A combination of genomic in situ hybridization (GISH) and meiotic pairing analysis of wheat-Thinopyrum partial amphiploids was employed to identify the genomic constitution and relationships between partial amphiploids derived from wheat and wheatgrass crosses. On the basis of similarities in the meiotic behavior and GISH patterns, the alien chromosomes of two of eight partial amphiploids, TAF46 and 'Otrastayuskaya 38', were judged to originate from Th. intermedium, whereas Th. ponticum was one of the parents of the other six partial amphiploids; PWM706, PWM206, PWM209, PWMIII, OK7211542, and Ag-wheat hybrid. Each of these partial amphiploids was found to contain a synthetic alien genome composed of different combinations of St-, J-, or Js-genome chromosomes. For relatedness of partial amphiploid lines, meiotic analysis of F1 hybrids and GISH results were generally complementary, but the latter offered greater precision in identifying constituent genomes. PMID:10984185

  18. Preliminary Results Obtained in Integrated Safety Analysis of NASA Aviation Safety Program Technologies

    NASA Technical Reports Server (NTRS)

    Reveley, Mary S.

    2003-01-01

    The goal of the NASA Aviation Safety Program (AvSP) is to develop and demonstrate technologies that contribute to a reduction in the aviation fatal accident rate by a factor of 5 by the year 2007 and by a factor of 10 by the year 2022. Integrated safety analysis of day-to-day operations and risks within those operations will provide an understanding of the Aviation Safety Program portfolio. Safety benefits analyses are currently being conducted. Preliminary results for the Synthetic Vision Systems (SVS) and Weather Accident Prevention (WxAP) projects of the AvSP have been completed by the Logistics Management Institute under a contract with the NASA Glenn Research Center. These analyses include both a reliability analysis and a computer simulation model. The integrated safety analysis method comprises two principal components: a reliability model and a simulation model. In the reliability model, the results indicate how different technologies and systems will perform in normal, degraded, and failed modes of operation. In the simulation, an operational scenario is modeled. The primary purpose of the SVS project is to improve safety by providing visual-flightlike situation awareness during instrument conditions. The current analyses are an estimate of the benefits of SVS in avoiding controlled flight into terrain. The scenario modeled has an aircraft flying directly toward a terrain feature. When the flight crew determines that the aircraft is headed toward an obstruction, the aircraft executes a level turn at speed. The simulation is ended when the aircraft completes the turn.

  19. Multilevel Analysis Methods for Partially Nested Cluster Randomized Trials

    ERIC Educational Resources Information Center

    Sanders, Elizabeth A.

    2011-01-01

    This paper explores multilevel modeling approaches for 2-group randomized experiments in which a treatment condition involving clusters of individuals is compared to a control condition involving only ungrouped individuals, otherwise known as partially nested cluster randomized designs (PNCRTs). Strategies for comparing groups from a PNCRT in the…

  20. Advancements in partial discharge analysis to diagnose stator winding problems

    Microsoft Academic Search

    V. Warren; G. C. Stone; M. Fenger

    2000-01-01

    On-line partial discharge (PD) testing has been used for over 50 years to assess the condition of motor and generator stator winding insulation systems. In the past decade, advanced hardware and software have enabled superior methods of converting the PD data into practical information about the relative condition of the insulation, as well as determining the root causes of any

  1. A guide for performing system safety analysis

    NASA Technical Reports Server (NTRS)

    Brush, J. M.; Douglass, R. W., III.; Williamson, F. R.; Dorman, M. C. (editor)

    1974-01-01

    A general guide is presented for performing system safety analyses of hardware, software, operations and human elements of an aerospace program. The guide describes a progression of activities that can be effectively applied to identify hazards to personnel and equipment during all periods of system development. The general process of performing safety analyses is described; setting forth in a logical order the information and data requirements, the analytical steps, and the results. These analyses are the technical basis of a system safety program. Although the guidance established by this document cannot replace human experience and judgement, it does provide a methodical approach to the identification of hazards and evaluation of risks to the system.

  2. Using Qualitative Hazard Analysis to Guide Quantitative Safety Analysis

    NASA Technical Reports Server (NTRS)

    Shortle, J. F.; Allocco, M.

    2005-01-01

    Quantitative methods can be beneficial in many types of safety investigations. However, there are many difficulties in using quantitative m ethods. Far example, there may be little relevant data available. This paper proposes a framework for using quantitative hazard analysis to prioritize hazard scenarios most suitable for quantitative mziysis. The framework first categorizes hazard scenarios by severity and likelihood. We then propose another metric "modeling difficulty" that desc ribes the complexity in modeling a given hazard scenario quantitatively. The combined metrics of severity, likelihood, and modeling difficu lty help to prioritize hazard scenarios for which quantitative analys is should be applied. We have applied this methodology to proposed concepts of operations for reduced wake separation for airplane operatio ns at closely spaced parallel runways.

  3. Operators on Partial Inner Product Spaces: Towards a Spectral Analysis

    E-print Network

    Jean-Pierre Antoine; Camillo Trapani

    2014-09-10

    Given a LHS (Lattice of Hilbert spaces) $V_J$ and a symmetric operator $A$ in $V_J$, in the sense of partial inner product spaces, we define a generalized resolvent for $A$ and study the corresponding spectral properties. In particular, we examine, with help of the KLMN theorem, the question of generalized eigenvalues associated to points of the continuous (Hilbertian) spectrum. We give some examples, including so-called frame multipliers.

  4. Pattern analysis of partial discharges in SF6 GIS

    Microsoft Academic Search

    S. Meijer; E. Gulski; J. J. Smit

    1998-01-01

    The measurement of partial discharge(PD) of several faults in gas-insulated system (GIS) is discussed. Phase-resolved PD patterns have been measured using three different PD detection measuring systems: according to the IEC 270 recommendations, a VHF\\/UHF measuring system with narrow band filtering, and the UHF measuring system with wide band filtering. PD patterns are compared using computer-based discrimination tools. The influence

  5. A stability analysis for a semilinear parabolic partial differential equation

    NASA Technical Reports Server (NTRS)

    Chafee, N.

    1973-01-01

    The parabolic partial differential equation considered is u sub t = u sub xx + f(u), where minus infinity x plus infinity and o t plus infinity. Under suitable hypotheses pertaining to f, a class of initial data is exhibited: phi(x), minus infinity x plus infinity, for which the corresponding solutions u(x,t) appraoch zero as t approaches the limit of plus infinity. This convergence is uniform with respect to x on any compact subinterval of the real axis.

  6. Preliminary Integrated Safety Analysis of Synthetic Vision Conducted

    NASA Technical Reports Server (NTRS)

    Reveley, Mary S.

    2002-01-01

    The goal of the NASA Aviation Safety Program is to develop and demonstrate technologies that could help reduce the aviation fatal accident rate by a factor of 5 by the year 2007 and by a factor of 10 by the year 2022. Integrated safety analysis of day-to-day operations and risks within those operations will provide an understanding of the Aviation Safety Program portfolio beyond what is now available. Synthetic vision is the first of the Aviation Safety Program technologies that has been analyzed by the Logistics Management Institute under a contract with the NASA Glenn Research Center. These synthetic vision analyses include both a reliability analysis and a computer simulation model.

  7. Hybrid Safety Analysis Using Functional and Risk Decompositions

    SciTech Connect

    COOPER,J. ARLIN; JOHNSON,ALICE J.; WERNER,PAUL W.

    2000-07-15

    Safety analysis of complex systems depends on decomposing the systems into manageable subsystems, from which analysis can be rolled back up to the system level. The authors have found that there is no single best way to decompose; in fact hybrid combinations of decompositions are generally necessary to achieve optimum results. They are currently using two backbone coordinated decompositions--functional and risk, supplemented by other types, such as organizational. An objective is to derive metrics that can be used to efficiently and accurately aggregate information through analysis, to contribute toward assessing system safety, and to contribute information necessary for defensible decisions.

  8. Safety analysis report for packaging (onsite) steel drum

    SciTech Connect

    McCormick, W.A.

    1998-09-29

    This Safety Analysis Report for Packaging (SARP) provides the analyses and evaluations necessary to demonstrate that the steel drum packaging system meets the transportation safety requirements of HNF-PRO-154, Responsibilities and Procedures for all Hazardous Material Shipments, for an onsite packaging containing Type B quantities of solid and liquid radioactive materials. The basic component of the steel drum packaging system is the 208 L (55-gal) steel drum.

  9. Safety verification in Murphy using fault tree analysis

    Microsoft Academic Search

    Stephen S. Cha; Nancy G. Leveson; Timothy J. Shimeall

    1988-01-01

    MURPHY is a language-independent, experimental methodology for building safety-critical, real time software, which will include an integrated tool set. Using Ada as an example, this paper presents a technique for verifying the safety of complex, real-time software using Software Fault Tree Analysis. The templates for Ada are presented along with an example of applying the technique to an Ada program.

  10. Software Safety Analysis of a Flight Guidance System

    NASA Technical Reports Server (NTRS)

    Butler, Ricky W. (Technical Monitor); Tribble, Alan C.; Miller, Steven P.; Lempia, David L.

    2004-01-01

    This document summarizes the safety analysis performed on a Flight Guidance System (FGS) requirements model. In particular, the safety properties desired of the FGS model are identified and the presence of the safety properties in the model is formally verified. Chapter 1 provides an introduction to the entire project, while Chapter 2 gives a brief overview of the problem domain, the nature of accidents, model based development, and the four-variable model. Chapter 3 outlines the approach. Chapter 4 presents the results of the traditional safety analysis techniques and illustrates how the hazardous conditions associated with the system trace into specific safety properties. Chapter 5 presents the results of the formal methods analysis technique model checking that was used to verify the presence of the safety properties in the requirements model. Finally, Chapter 6 summarizes the main conclusions of the study, first and foremost that model checking is a very effective verification technique to use on discrete models with reasonable state spaces. Additional supporting details are provided in the appendices.

  11. Partial wave analysis at BES III harnessing the power of GPUs

    E-print Network

    Niklaus Berger

    2011-08-29

    Partial wave analysis is a core tool in hadron spectroscopy. With the high statistics data available at facilities such as the Beijing Spectrometer III, this procedure becomes computationally very expensive. We have successfully implemented a framework for performing partial wave analysis on graphics processors. We discuss the implementation, the parallel computing frameworks employed and the performance achieved, with a focus on the recent transition to the OpenCL framework.

  12. RISMC ADVANCED SAFETY ANALYSIS WORKING PLAN – FY 2015 – FY 2019

    SciTech Connect

    Szilard, Ronaldo H; Smith, Curtis L

    2014-09-01

    SUMMARY In this report, the Advanced Safety Analysis Program (ASAP) objectives and value proposition is described. ASAP focuses on modernization of nuclear power safety analysis (tools, methods and data); implementing state-of-the-art modeling techniques (which include, for example, enabling incorporation of more detailed physics as they become available); taking advantage of modern computing hardware; and combining probabilistic and mechanistic analyses to enable a risk informed safety analysis process. The modernized tools will maintain the current high level of safety in our nuclear power plant fleet, while providing an improved understanding of safety margins and the critical parameters that affect them. Thus, the set of tools will provide information to inform decisions on plant modifications, refurbishments, and surveillance programs, while improving economics. The set of tools will also benefit the design of new reactors, enhancing safety per unit cost of a nuclear plant. As part of the discussion, we have identified three sets of stakeholders, the nuclear industry, the Department of Energy (DOE), and associated oversight organizations. These three groups would benefit from ASAP in different ways. For example, within the DOE complex, the possible applications that are seen include the safety of experimental reactors, facility life extension, safety-by-design in future generation advanced reactors, and managing security for the storage of nuclear material. This report provides information in five areas: 1. A value proposition (“why is this important?”) that will make the case for stakeholder’s use of the ASAP research and development (R&D) products. 2. An identification of likely end users and pathway to adoption of enhanced tools by the end-users. 3. A proposed set of practical and achievable “use case” demonstrations. 4. A proposed plan to address ASAP verification and validation (V&V) needs. 5. A proposed schedule for the multi-year ASAP.

  13. An Analysis of Relational Storage Strategies for Partially Structured Yasser Abdel Kader1

    E-print Network

    North, Siobhán

    An Analysis of Relational Storage Strategies for Partially Structured XML Yasser Abdel Kader1.North}@sheffield.ac.uk Keywords: XML databases, structure mapping, performance analysis Abstract: This paper presents that are a combination of structured and semi-structured data. The analysis demonstrates advantages of a hybrid approach

  14. Safety analysis of the existing 850 Firing Facility

    SciTech Connect

    Odell, B.N.

    1986-06-05

    A safety analysis was performed to determine if normal operations and/or potential accidents at the 850 Firing Facility at Site 300 could present undue hazards to the general public, personnel at Site 300, or have an adverse effect on the environment. The normal operations and credible accidents that might have an effect on these facilities or have off-site consequences were considered. It was determined by this analysis that all but one of the hazards were either low or of the type or magnitude routinely encountered and/or accepted by the public. The exception was explosives, which was classified as a moderate hazard per the requirements given in DOE Order 5481.1A. This safety analysis concluded that the operation at this facility will present no undue risk to the health and safety of LLNL employees or the public.

  15. System safety analysis of an autonomous mobile robot

    SciTech Connect

    Bartos, R.J.

    1994-08-01

    Analysis of the safety of operating and maintaining the Stored Waste Autonomous Mobile Inspector (SWAMI) II in a hazardous environment at the Fernald Environmental Management Project (FEMP) was completed. The SWAMI II is a version of a commercial robot, the HelpMate{trademark} robot produced by the Transitions Research Corporation, which is being updated to incorporate the systems required for inspecting mixed toxic chemical and radioactive waste drums at the FEMP. It also has modified obstacle detection and collision avoidance subsystems. The robot will autonomously travel down the aisles in storage warehouses to record images of containers and collect other data which are transmitted to an inspector at a remote computer terminal. A previous study showed the SWAMI II has economic feasibility. The SWAMI II will more accurately locate radioactive contamination than human inspectors. This thesis includes a System Safety Hazard Analysis and a quantitative Fault Tree Analysis (FTA). The objectives of the analyses are to prevent potentially serious events and to derive a comprehensive set of safety requirements from which the safety of the SWAMI II and other autonomous mobile robots can be evaluated. The Computer-Aided Fault Tree Analysis (CAFTA{copyright}) software is utilized for the FTA. The FTA shows that more than 99% of the safety risk occurs during maintenance, and that when the derived safety requirements are implemented the rate of serious events is reduced to below one event per million operating hours. Training and procedures in SWAMI II operation and maintenance provide an added safety margin. This study will promote the safe use of the SWAMI II and other autonomous mobile robots in the emerging technology of mobile robotic inspection.

  16. Comprehensive safety analysis for pressure and cryogenic systems facilities

    SciTech Connect

    Blyukher, B. [Indiana State Univ., Terre Haute, IN (United States). Health and Safety Dept.

    1996-12-01

    There have been many instances where serious injuries and fatalities have resulted from over-pressurization, thermal stress, asphyxiation and other potential hazards associated with testing, handling and storage of compressed gases and cryogenic liquids at numerous production and research facilities. These hazards are major issues that should be addressed in system design and in materials selection appropriate for high pressure or cryogenic temperature applications. Potential hazards may be mitigated through system analysis and design process which are the major factors in preventing thermal/pressure hazards caused by possible leaks and fragmentation, in the case of rupture. This paper presents a conceptual model and framework for developing a comprehensive safety analysis which will reduce potential hazards, accidents and legal liabilities. The proposed in-depth system Safety Analysis Report (SAR) is a proven systematic approach to identify hazards and influence design to provide timely documentation of potential hazards and risks associated with systems, facilities, and equipment. As a result of this hazard analysis process, provisions and actions for hazard prevention, elimination, mitigation, and control have been put in place, and all identifiable potential hazards have been reduced to a low risk level. These methods are demonstrated in the example of comprehensive safety analysis of Cryogenic Subsystem of Accelerator String Test facilities (ASST) at Superconducting Super Collider Laboratory by developing Safety Analysis Report (SSC Laboratory, 1992).

  17. Market analysis of biosensors for food safety.

    PubMed

    Alocilja, Evangelyn C; Radke, Stephen M

    2003-05-01

    This paper is presented as an overview of the pathogen detection industry. The review includes pathogen detection markets and their prospects for the future. Potential markets include the medical, military, food, and environmental industries. Those industries combined have a market size of $563 million for pathogen detecting biosensors and are expected to grow at a compounded annual growth rate of 4.5%. The food market is further segmented into different food product industries. The overall food-pathogen testing market is expected to grow to $192 million and 34 million tests by 2005. The trend in pathogen testing emphasizes the need to commercialize biosensors for the food safety industry as legislation creates new standards for microbial monitoring. With quicker detection time and reusable features, biosensors will be important to those interested in real time diagnostics of disease causing pathogens. As the world becomes more concerned with safe food and water supply, the demand for rapid detecting biosensors will only increase. PMID:12706600

  18. COLLECTION OF MICRO-LEVEL SAFETY AND EFFICIENCY INDICATORS WITH AUTOMATED VIDEO ANALYSIS

    E-print Network

    Lunds Universitet

    , interaction process, automated video analysis INTRODUCTION Safety and indicators on safety Traffic safety and the sometimes devastating consequences that is the aim of traffic safety work but in order to get there we need to explore the traffic safety processes; we need to better understand the relationship between road user

  19. Three-dimensional analysis of partially open butterfly valve flows

    SciTech Connect

    Huang, C.; Kim, R.H. [Univ. of North Carolina, Charlotte, NC (United States). Dept. of Mechanical Engineering and Engineering Science

    1996-09-01

    A numerical simulation of butterfly valve flows is a useful technique to investigate the physical phenomena of the flow field. A three-dimensional numerical analysis was carried out on incompressible fluid flows in a butterfly valve by using FLUENT, which solves difference equations. Characteristics of the butterfly valve flows at different valve disk angles with a uniform incoming velocity were investigated. Comparisons of FLUENT results with other results, i.e., experimental results, were made to determine the accuracy of the employed method. Results of the three-dimensional analysis may be useful in the valve design.

  20. Impact of Feature Interaction on the Safety Analysis for Unmanned Avionics Product Lines

    E-print Network

    Boyer, Edmond

    Impact of Feature Interaction on the Safety Analysis for Unmanned Avionics Product Lines André L software [3]. Safety- critical product-lines, such as avionics systems, include high- integrity safety-critical SPLs, for which it should be considered in both product-line development and safety analysis

  1. Applicability of trends in nuclear safety analysis to space nuclear power systems

    SciTech Connect

    Bari, R.A.

    1992-10-01

    A survey is presented of some current trends in nuclear safety analysis that may be relevant to space nuclear power systems. This includes: lessons learned from operating power reactor safety and licensing; approaches to the safety design of advanced and novel reactors and facilities; the roles of risk assessment, extremely unlikely accidents, safety goals/targets; and risk-benefit analysis and communication.

  2. Transportation Center Seminar... Analysis of Highway-Safety Data

    E-print Network

    Bustamante, Fabián E.

    Transportation Center Seminar... Analysis of Highway-Safety Data: Current than 1.2 million people die annually in highway-related crashes and as many highway-related crashes to be the 5th leading cause of death in the world

  3. Legislating Traffic Safety: A Pooled Time Series Analysis

    Microsoft Academic Search

    David J. Houston; E. Richardson Jr.; Grant W. Neeley

    Objective. This study assesses the effectiveness of state regulatory efforts to improve traffic safety. Methods. Annual data for the period 1967-1991 for all 50 states were analyzed through the use of pooled time series analysis. Results. Mandatory seat belt laws, an increased minimum legal drinking age, and a 55- mph maximum speed limit were found to reduce state traffic fatality

  4. Implementation of the Generic Safety Analysis Report - Lessons Learned

    SciTech Connect

    Blanchard, A.

    1999-06-02

    The Savannah River Site has completed the development, review and approval process for the Generic Safety Analysis Report (GSAR) and implemented this information in facility SARs and BIOs. This includes the yearly revision of the GSAR and the facility-specific SARs. The process has provided us with several lessons learned.

  5. Level1 Probabilistic Safety Analysis of Prototype Fast Breeder Reactor

    Microsoft Academic Search

    M. Ramakrishnan; Pramod Kumar Sharma; A. J. Arul; V. Bhuvana; P. Mohanakrishnan; S. C. Chetal

    2010-01-01

    This paper summarizes the results from the level-1 Probabilistic Safety Analysis of Prototype Fast Breeder Reactor (PFBR) which is under construction at Kalpakkam. The scope of this study is limited to internal events at full power. The regulatory requirement in India is risk informed and the required target value for overall core damage frequency (CDF) <; le-6 \\/ ry. The

  6. Data-Replay Analysis of LAAS Safety during Ionosphere Storms

    E-print Network

    Stanford University

    Data-Replay Analysis of LAAS Safety during Ionosphere Storms Young Shin Park, Godwin Zhang, Sam research has identified the potential for severe ionosphere spatial gradients to affect Local Area was used to maximize LAAS availability in the presence of ionosphere anomalies by broadcasting an inflated

  7. Safety Analysis for Packaging Steel Banded Wooden Shipping Containers

    SciTech Connect

    FERRELL, P.C.

    2000-12-05

    This safety analysis report for packaging describes the steel banded wooden shipping containers, which are certified as Type AF packagings. The authorized payload for these containers is unirradiated, slightly enriched, uranium ingots, billets, extrusions, and scrap materials. The amount of uranium in the containers will not exceed the LSA-II material requirements as defined in 49 CFR 173.403.

  8. Safety Analysis of Sugar Cataract Development Using Stochastic Hybrid Systems

    E-print Network

    Koutsoukos, Xenofon D.

    Safety Analysis of Sugar Cataract Development Using Stochastic Hybrid Systems Derek Riley continuous dynamics [6]. In this paper we model Sugar Cataract Development (SCD) as a SHS, and we present a probabilistic verification method for computing the probability of sugar cataract formation for different

  9. Safety analysis of irradiated nuclear fuel transportation container

    SciTech Connect

    Uspuras, E.; Rimkevicius, S. [Lithuanian Energy Institute, 3 Breslaujos str., LT-3035 Kaunas (Lithuania)

    2007-07-01

    Ignalina NPP comprises two Units with RBMK-1500 reactors. After the Unit 1 of the Ignalina Nuclear Power Plant was shut down in 2004, approximately 1000 fuel assemblies from Unit were available for further reuse in Unit 2. The fuel-transportation container, vehicle, protection shaft and other necessary equipment were designed in order to implement the process for on-site transportation of Unit 1 fuel for reuse in the Unit 2. The Safety Analysis Report (SAR) was developed to demonstrate that the proposed set of equipment performs all functions and assures the required level of safety for both normal operation and accident conditions. The purpose of this paper is to introduce the content and main results of SAR, focusing attention on the container used to transport spent fuel assemblies from Unit I on Unit 2. In the SAR, the structural integrity, thermal, radiological and nuclear safety calculations are performed to assess the acceptance of the proposed set of equipment. The safety analysis demonstrated that the proposed nuclear fuel transportation container and other equipment are in compliance with functional, design and regulatory requirements and assure the required safety level. (authors)

  10. Convergence Analysis of Adaptive Partial FEXT cancellation precoder for multichannel

    E-print Network

    Bergel, Itsik

    of canceled FEXT terms. The same work also analyzed the resulting performance as a function of the system the existing copper infrastructure. Thus, Rx modems are scattered at different customer premises equipment (CPE and presented convergence conditions and steady state performance analysis. In that work it was also suggested

  11. Three-dimensional analysis of partially open butterfly valve flows

    Microsoft Academic Search

    Chendong Huang; Rhyn H. Kim

    1996-01-01

    A numerical simulation of butterfly valve flows is a useful technique to investigate the physical phenomena of the flow field. A three-dimensional numerical analysis was carried out on incompressible fluid flows in a butterfly valve by using FLUENT, which solves difference equations. Characteristics of the butterfly valve flows at different valve disk angles with a uniform incoming velocity were investigated.

  12. A novel technique for partial discharge and breakdown investigation based on current pulse waveform analysis

    Microsoft Academic Search

    Hitoshi Okubo; Naoki Hayakawa

    2005-01-01

    A novel technique for partial discharge (PD) measurement and analysis (PD-CPWA; PD current pulse waveform analysis) is developed and introduced in this paper. PD-CPWA is expected to be utilized to discuss PD mechanisms and physics in electrical insulating materials, focusing on the PD current pulse waveform and its time transition from PD inception to breakdown (BD). In this paper, the

  13. Analysis of Factors Affecting Containment with Extracted Partial Enclosures Using Computational Fluid Dynamics

    PubMed Central

    Batt, Rachel L.; Kelsey, Adrian

    2014-01-01

    The Health and Safety Executive’s (HSE’s) COSHH Essentials (HSE, 2002, COSHH Essentials: easy steps to control chemicals HSG193. 2nd edn. ISBN 0 71762737 3. Available at http://www.coshh-essentials.org.uk. Accessed 30 October 2013) provides guidance on identifying the approaches required to control exposure to chemicals in the workplace. The control strategies proposed in COSHH Essentials are grouped into four control approaches: general ventilation, engineering control, containment, or to seek specialist advice. We report the use of experimental measurements and computational fluid dynamics (CFD) modelling to examine the performance of an engineering control approach and a containment control approach. The engineering control approach simulated was an extracted partial enclosure, based on the COSHH Essentials G200, for which simulations were compared with data from experiments. The containment approach simulated was of drum filling (in an extracted partial enclosure), based on the COSHH Essentials G305. The influence of the following factors on containment was examined: face velocity, size and location of face opening, and movement and ventilation flows. CFD predictions of the engineering control approach agreed well with the majority of the experimental measurements demonstrating confidence in the modelling approach used. The results show that the velocity distribution at the face of the enclosure is not uniform and the location and size of the opening are significant factors affecting the flow field and hence the containment performance. The simulations of drum filling show the effect on containment of the movement of a drum through the face of an enclosure. Analysis of containment performance, using a tracer, showed that containment was affected by the interaction between the ventilation flow direction and drum movement and spacing. Validated CFD simulations are shown to be a useful tool for gaining insight into the flows in control strategies for exposure control and to aid the interpretation of experimental measurements. The results support the assumption in COSHH Essentials that the use of ‘containment’ as a control approach is capable of achieving a 100-fold reduction in potential exposure. Novel CFD modelling techniques have been used to create controlled containment scenarios, improve understanding of the flow behaviour in the scenarios, and provide information that may aid future containment design. PMID:24232543

  14. Safety analysis of plasma anomaly consequences in fusion reactors

    Microsoft Academic Search

    T. Honda; T. Okazaki; Y. Seki; T. Kunugi; I. Aoki

    1995-01-01

    Plasma anomaly consequences in the ITER-CDA (International Thermonuclear Experimental Reactor-Conceptual Design Activity) reactor have been investigated by using a comprehensive safety analysis code for fusion reactors. In this paper, the analysis results are shown for power excursion, disruptions, ex-vessel LOCA and dust production due to disruption. The code will be modified to apply it to the ITER-EDA (Engineering Design Activity)

  15. Safety analysis of SISL process module

    SciTech Connect

    Not Available

    1983-05-01

    This report provides an assessment of various postulated accidental occurrences within an experimental process module which is part of a Special Isotope Separation Laboratory (SISL) currently under construction at the Lawrence Livermore National Laboratory (LLNL). The process module will contain large amounts of molten uranium and various water-cooled structures within a vacuum vessel. Special emphasis is therefore given to potential accidental interactions of molten uranium with water leading to explosive and/or rapid steam formation, as well as uranium oxidation and the potential for combustion. Considerations are also given to the potential for vessel melt-through. Evaluations include mechanical and thermal interactions and design implications both in terms of design basis as well as once-in-a-lifetime accident scenarios. These scenarios include both single- and multiple-failure modes leading to various contact modes and locations within the process module for possible thermal interactions. The evaluations show that a vacuum vessel design based upon nominal operating conditions would appear sufficient to meet safety requirements in connection with both design basis as well as once-in-a-lifetime accidents. Controlled venting requirements for removal of steam and hydrogen in order to avoid possible long-term pressurization events are recommended. Depending upon the resulting accident conditions, the vacuum system (i.e., the roughing system) could also serve this purpose. Finally, based upon accident evaluations of this study, immediate shut-off of all coolant water following an incident leak is not recommended, as such action may have adverse effects in terms of cool-down requirements for the melt crucibles etc. These requirements have not been assessed as part of this study.

  16. Moon manned missions radiation safety analysis

    Microsoft Academic Search

    R. K. Tripathi; J. W. Wilson; G. de Anlelis; F. F. Badavi

    2004-01-01

    An analysis is performed on the radiation environment found on the surface of the Moon, and applied to different possible lunar base mission scenarios. An optimization technique has been used to obtain mission scenarios minimizing the astronaut radiation exposure and at the same time controlling the effect of shielding, in terms of mass addition and material choice, as a mission

  17. Safety analysis report for packaging (onsite) multicanister overpack cask

    SciTech Connect

    Edwards, W.S.

    1997-07-14

    This safety analysis report for packaging (SARP) documents the safety of shipments of irradiated fuel elements in the MUlticanister Overpack (MCO) and MCO Cask for a highway route controlled quantity, Type B fissile package. This SARP evaluates the package during transfers of (1) water-filled MCOs from the K Basins to the Cold Vacuum Drying Facility (CVDF) and (2) sealed and cold vacuum dried MCOs from the CVDF in the 100 K Area to the Canister Storage Building in the 200 East Area.

  18. Fuel Storage Facility Final Safety Analysis Report. Revision 1

    SciTech Connect

    Linderoth, C.E.

    1984-03-01

    The Fuel Storage Facility (FSF) is an integral part of the Fast Flux Test Facility. Its purpose is to provide long-term storage (20-year design life) for spent fuel core elements used to provide the fast flux environment in FFTF, and for test fuel pins, components and subassemblies that have been irradiated in the fast flux environment. This Final Safety Analysis Report (FSAR) and its supporting documentation provides a complete description and safety evaluation of the site, the plant design, operations, and potential accidents.

  19. Style, content and format guide for writing safety analysis documents. Volume 1, Safety analysis reports for DOE nuclear facilities

    SciTech Connect

    Not Available

    1994-06-01

    The purpose of Volume 1 of this 4-volume style guide is to furnish guidelines on writing and publishing Safety Analysis Reports (SARs) for DOE nuclear facilities at Sandia National Laboratories. The scope of Volume 1 encompasses not only the general guidelines for writing and publishing, but also the prescribed topics/appendices contents along with examples from typical SARs for DOE nuclear facilities.

  20. SCALE 6: Comprehensive Nuclear Safety Analysis Code System

    SciTech Connect

    Bowman, Stephen M [ORNL

    2011-01-01

    Version 6 of the Standardized Computer Analyses for Licensing Evaluation (SCALE) computer software system developed at Oak Ridge National Laboratory, released in February 2009, contains significant new capabilities and data for nuclear safety analysis and marks an important update for this software package, which is used worldwide. This paper highlights the capabilities of the SCALE system, including continuous-energy flux calculations for processing multigroup problem-dependent cross sections, ENDF/B-VII continuous-energy and multigroup nuclear cross-section data, continuous-energy Monte Carlo criticality safety calculations, Monte Carlo radiation shielding analyses with automated three-dimensional variance reduction techniques, one- and three-dimensional sensitivity and uncertainty analyses for criticality safety evaluations, two- and three-dimensional lattice physics depletion analyses, fast and accurate source terms and decay heat calculations, automated burnup credit analyses with loading curve search, and integrated three-dimensional criticality accident alarm system analyses using coupled Monte Carlo criticality and shielding calculations.

  1. General aviation air traffic pattern safety analysis

    NASA Technical Reports Server (NTRS)

    Parker, L. C.

    1973-01-01

    A concept is described for evaluating the general aviation mid-air collision hazard in uncontrolled terminal airspace. Three-dimensional traffic pattern measurements were conducted at uncontrolled and controlled airports. Computer programs for data reduction, storage retrieval and statistical analysis have been developed. Initial general aviation air traffic pattern characteristics are presented. These preliminary results indicate that patterns are highly divergent from the expected standard pattern, and that pattern procedures observed can affect the ability of pilots to see and avoid each other.

  2. Multivariate qualitative analysis of banned additives in food safety using surface enhanced Raman scattering spectroscopy.

    PubMed

    He, Shixuan; Xie, Wanyi; Zhang, Wei; Zhang, Liqun; Wang, Yunxia; Liu, Xiaoling; Liu, Yulong; Du, Chunlei

    2015-02-25

    A novel strategy which combines iteratively cubic spline fitting baseline correction method with discriminant partial least squares qualitative analysis is employed to analyze the surface enhanced Raman scattering (SERS) spectroscopy of banned food additives, such as Sudan I dye and Rhodamine B in food, Malachite green residues in aquaculture fish. Multivariate qualitative analysis methods, using the combination of spectra preprocessing iteratively cubic spline fitting (ICSF) baseline correction with principal component analysis (PCA) and discriminant partial least squares (DPLS) classification respectively, are applied to investigate the effectiveness of SERS spectroscopy for predicting the class assignments of unknown banned food additives. PCA cannot be used to predict the class assignments of unknown samples. However, the DPLS classification can discriminate the class assignment of unknown banned additives using the information of differences in relative intensities. The results demonstrate that SERS spectroscopy combined with ICSF baseline correction method and exploratory analysis methodology DPLS classification can be potentially used for distinguishing the banned food additives in field of food safety. PMID:25300041

  3. Safety Analysis of Software Product Lines Using State-Based Modeling

    Microsoft Academic Search

    Jing Liu; Josh Dehlinger; Robyn R. Lutz

    2005-01-01

    The analysis and management of variations (such as optional features) are central to the development of safety-critical, software product lines. However, the difficulty of managing variations, and the potential interactions among them, across an entire product line currently hinders safety analysis in such systems. The work described here contributes to a solution by integrating safety analysis of a product line

  4. Safety Analysis of Software Architectures "Lightweight PSSA" O. Lisagor; Department of Computer Science, The University of York; York, UK

    E-print Network

    Pumfrey, David

    to aircraft (and engines). This process explicitly identifies Preliminary System Safety Assessment (PSSA): "aSafety Analysis of Software Architectures ­ "Lightweight PSSA" O. Lisagor; Department of Computer, UK Keywords: preliminary system safety assessment, lightweight safety assessment, software

  5. Limited-scope probabilistic safety analysis for the Los Alamos Meson Physics Facility (LAMPF)

    Microsoft Academic Search

    M. Sharirli; J. L. Rand; M. K. Sasser; F. R. Gallegos

    1992-01-01

    The reliability of instrumentation and safety systems is a major issue in the operation of accelerator facilities. A probabilistic safety analysis was performed or the key safety and instrumentation systems at the Los Alamos Meson Physics Facility (LAMPF). in Phase I of this unique study, the Personnel Safety System (PSS) and the Current Limiters (XLs) were analyzed through the use

  6. ECE 2100 Circuit Analysis Laboratory: Safety and Rules updated 8 October 2010

    E-print Network

    Miller, Damon A.

    . FAILURE TO OBSERVE ALL SAFETY RULES WILL RESULT IN YOUR REMOVAL FROM THE LABORATORY AND FAILURE IN THE LAB1 ECE 2100 Circuit Analysis Laboratory: Safety and Rules updated 8 October 2010 Safety safety precautions, and common sense. There are a number of hazards present in any electrical engineering

  7. Safety analysis report for packaging (onsite) sample pig transport system

    SciTech Connect

    MCCOY, J.C.

    1999-03-16

    This Safety Analysis Report for Packaging (SARP) provides a technical evaluation of the Sample Pig Transport System as compared to the requirements of the U.S. Department of Energy, Richland Operations Office (RL) Order 5480.1, Change 1, Chapter III. The evaluation concludes that the package is acceptable for the onsite transport of Type B, fissile excepted radioactive materials when used in accordance with this document.

  8. Summary of experimental testing in support of ANSR safety analysis

    SciTech Connect

    Felde, D.K.; Crabtree, J.A.; Pawel, S.J.; Siman-Tov, M.; Swinson, W.F.; Yoder, G.L. [Lockheed Martin Energy Systems, Inc., Oak Ridge, TN (United States)

    1996-12-31

    A number of test facilities have been built in the last 7 yr to provide support to the Advanced Neutron Source Reactor (ANSR) design development and safety analysis. These facilities have provided required data and analytical model benchmarks critical to the project. This paper provides a summary of the results obtained from four test programs [corrosion testing, critical heat flux (CHF) and flow instability testing, flow blockage testing, and fuel plate stability testing].

  9. Factors Analysis on Safety of Indoor Air Quality

    E-print Network

    Luo, Q.; Liu, Z.; Xiong, J.

    2006-01-01

    ICEBO2006, Shenzhen, China Maximize Comfort: Temperature, Humidity and IAQ Vol.I-7-5 Factors Analysis on Safety of Indoor Air Quality Qing-hai Luo Ze-hua Liu Jun Xiong Doc., Associate Prof. Professor Associate Prof. College... IAQ and operating efficiency. Liu et al [6] introduced special cleaning equipments and cleaning process for HAVC system. Table 1 presents the comparison between data of supply air, return air and bacteria in two guest rooms of a hotel before...

  10. Protein Folding Trajectories Analysis: Summarization, Event Detection and Consensus Partial Folding Pathway

    E-print Network

    Yang, Hui

    Protein Folding Trajectories Analysis: Summarization, Event Detection and Consensus Partial Folding in protein folding trajectories. We pro- pose an approach that employs the simplicity of contact maps and po- tentially cure diseases caused by misfolding. The protein folding problem is therefore one

  11. Interdependence of Multiple Theta Generators in the Hippocampus: a Partial Coherence Analysis

    Microsoft Academic Search

    Bernat Kocsis; Anatol Bragin; Gyorgy Buzsak

    The extracellularly recorded theta oscillation reflects a dynamic interaction of various synaptic and cellular mechanisms. Be- cause the spatially overlapping dipoles responsible for the generation of theta field oscillation may represent different mechanisms, their separation might provide clues with regard to their origin and significance. We used a novel approach, partial coherence analysis, to reveal the various components of the

  12. Design and partial load exergy analysis of hybrid SOFC–GT power plant

    Microsoft Academic Search

    F. Calise; A. Palombo; L. Vanoli

    2006-01-01

    This paper presents a full and partial load exergy analysis of a hybrid SOFC–GT power plant. The plant basically consists of: an air compressor, a fuel compressor, several heat exchangers, a radial gas turbine, mixers, a catalytic burner, an internal reforming tubular solid oxide fuel cell stack, bypass valves, an electrical generator and an inverter. The model is accurately described.

  13. Analysis of a local transient control action by partial energy functions

    Microsoft Academic Search

    S. E. Stanton; W. P. Dykas

    1989-01-01

    A partial energy function is used to quantify the energy of a local transient control action. The function is used to analyze the energy transactions of a single generator in a multimachine power system. This is in contrast with a global energy analysis of the system. Special attention is drawn to an explanation of damping as being caused by tuned

  14. Analysis of a Local Transient Control Action by Partial Energy Functions

    Microsoft Academic Search

    S. E. Stanton; W. P. Dykas

    1989-01-01

    In this paper, a partial energy function is used to quantify the energy of a local transient control action. The function is used to analyze the energy transactions of a single generator in a multimachine system. This is in contrast with a global energy analysis of the system. Dynamic braking is considered.

  15. Phylogenetic Analysis of Partial Sequences of Elongation Factor 1 Identifies Major Groups of Lice (Insecta: Phthiraptera)

    E-print Network

    Johnson, Kevin P.

    of mammal lice). The relationships among these suborders are poorly understood. Early attempts to resolvePhylogenetic Analysis of Partial Sequences of Elongation Factor 1 Identifies Major Groups of Lice, 2000 As a first attempt to use molecular data to resolve the relationships between the four suborders

  16. Functional coupling of human right and left cortical motor areas demonstrated with partial coherence analysis

    Microsoft Academic Search

    Tatsuya Mima; Takahiro Matsuoka; Mark Hallett

    2000-01-01

    Although a linear correlation between oscillatory activities in the right and left motor cortices during movements has been shown in monkeys, there has been a debate whether scalp-recorded EEG coherence in human reflects a similar association. By applying partial coherence analysis, we demonstrated that interhemispheric coherence during movements cannot be explained by contamination from the occipital alpha rhythm or common

  17. Investigating Importance Weighting of Satisfaction Scores from a Formative Model with Partial Least Squares Analysis

    ERIC Educational Resources Information Center

    Wu, Chia-Huei; Chen, Lung Hung; Tsai, Ying-Mei

    2009-01-01

    This study introduced a formative model to investigate the utility of importance weighting on satisfaction scores with partial least squares analysis. Based on the bottom-up theory of satisfaction evaluations, the measurement structure for weighted/unweighted domain satisfaction scores was modeled as a formative model, whereas the measurement…

  18. Partial unmixing as a tool for single surface class detection and time series analysis

    Microsoft Academic Search

    C. Kuenzer; M. Bachmann; A. Mueller; L. Lieckfeld; W. Wagner

    2008-01-01

    In this paper we present the results of time series analysis for a coal mining region based on partial unmixing. We test the method also known as mixture tuned matched filtering on an eight image Landsat 5 TM and Landsat 7 ETM+ time series covering the period from 1987 to 2003. Common change detection methods often include the comparison of

  19. Principle Component Analysis and Partial Least Squares: Two Dimension Reduction Techniques for Regression

    Microsoft Academic Search

    Saikat Maitra; Jun Yan

    2008-01-01

    Dimension reduction is one of the major tasks for multivariate analysis, it is especially critical for multivariate regressions in many P&C insurance-related applications. In this paper, we'll present two methodologies, principle component analysis (PCA) and partial least squares (PLC), for dimension reduction in a case that the independent variables used in a regression are highly correlated. PCA, as a dimension

  20. MEAN-SQUARED ANALYSIS OF THE PARTIAL-UPDATE NLMS ALGORITHM

    Microsoft Academic Search

    Stefan Werner; Marcello L. R. de Campos; Paulo S. R. Diniz

    In this paper, we present mean-squared conver- gence analysis for the partial-update normalized least-mean square (PU-NLMS) algorithm with closed-form expressions for the case of white input signals. The analysis uses order statistics and the formulas presented here are more accurate than the ones found in the literature for the PU-NLMS algo- rithm. Simulation results show excellent agreement with the the

  1. Deconvolution of variability and uncertainty in the Cassini safety analysis

    SciTech Connect

    Kampas, Frank J.; Loughin, Stephen [Lockheed Martin Missiles and Space, P.O. Box 8555, Philadelphia, Pennsylvania 19101 (United States); WAM Systems, 650 Loraine Street, Ardmore, Pennsylvania 19003 (United States)

    1998-01-15

    The standard method for propagation of uncertainty in a risk analysis requires rerunning the risk calculation numerous times with model parameters chosen from their uncertainty distributions. This was not practical for the Cassini nuclear safety analysis, due to the computationally intense nature of the risk calculation. A less computationally intense procedure was developed which requires only two calculations for each accident case. The first of these is the standard 'best-estimate' calculation. In the second calculation, variables and parameters change simultaneously. The mathematical technique of deconvolution is then used to separate out an uncertainty multiplier distribution, which can be used to calculate distribution functions at various levels of confidence.

  2. Partial-photoelectron-wave analysis in diatomic molecule photoionization by fluorescence polarization experiments

    SciTech Connect

    Demekhin, Ph. V. [Institute of Physics and CINSaT, University of Kassel, D-34132 Kassel (Germany); Rostov State University of Transport Communications, 344038 Rostov-on-Don (Russian Federation); Petrov, I. D. [Rostov State University of Transport Communications, 344038 Rostov-on-Don (Russian Federation); Ehresmann, A. [Institute of Physics and CINSaT, University of Kassel, D-34132 Kassel (Germany)

    2010-10-15

    Parameters {beta}1 and {beta}2 describing the angular distribution of circularly polarized fluorescence photons emitted by randomly oriented diatomic molecules excited by circularly polarized radiation are derived. We prove theoretically that measuring these parameters allows a partial-wave analysis of the emitted photoelectrons in the case of closed-shell diatomic molecules. The determination of the relative partial cross sections for emission of the {epsilon}{sigma}, {epsilon}{pi}, and {epsilon}{delta} photoelectrons is of fundamental importance for a sensitive test of corresponding calculations.

  3. Survey of systems safety analysis methods and their application to nuclear waste management systems

    Microsoft Academic Search

    P. J. Pelto; W. K. Winegardner; R. H. V. Gallucci

    1981-01-01

    This report reviews system safety analysis methods and examines their application to nuclear waste management systems. The safety analysis methods examined include expert opinion, maximum credible accident approach, design basis accidents approach, hazard indices, preliminary hazards analysis, failure modes and effects analysis, fault trees, event trees, cause consequence diagrams, GO methodology, Markov modeling, and a general category of consequence analysis

  4. Safety analysis of software product lines using state-based modeling q , Josh Dehlinger a

    E-print Network

    Lutz, Robyn R.

    Safety analysis of software product lines using state-based modeling q Jing Liu a , Josh Dehlinger of managing variations and their potential interactions across an entire product line currently hinders safety analysis in safety-critical, software product lines. The work described here contributes to a solution

  5. Bi-Directional Safety Analysis of Product Lines Department of Computer Science

    E-print Network

    Lutz, Robyn R.

    Bi-Directional Safety Analysis of Product Lines Qian Feng Department of Computer Science Iowa State safety-critical software product lines are being built. This paper describes a structured method for performing safety analysis on a software product line, building on standard product-line assets: product

  6. Facets of a Discourse Analysis of Safety Requirements Patrick Saint-Dizier

    E-print Network

    also emerged, e.g. EEC norms for chemical product storage and uses. Besides public regulations, safetyFacets of a Discourse Analysis of Safety Requirements Patrick Saint-Dizier IRIT - CNRS, 118 route a linguistic analysis and an implementation of the discourse structure of safety requirements within

  7. Analysis of the Safety Properties of a System from the Viewpoint of the

    E-print Network

    Newcastle upon Tyne, University of

    deals with the safety procedures associated with the launching and flight of a sounding rocket. KeywordsAnalysis of the Safety Properties of a System from the Viewpoint of the Interactions of its Science, Claremont Tower, Claremont Road, Newcastle upon Tyne, NE1 7RU, UK #12;3 Analysis of the Safety

  8. Multi-sensor analysis techniques for SSME safety monitoring

    NASA Technical Reports Server (NTRS)

    Maul, William A., III

    1990-01-01

    Two algorithms were developed which utilized multi-sensor analysis techniques to complement the current Space Shuttle Main Engine (SSME) safety monitoring system. The first algorithm analyzed the accumulative error between actual and predicted values of the engine parameter set, while the second algorithm combined these error terms into a response pattern and correlated each pattern with a standard pattern. These algorithms were applied to twelve SSME anomalous test firings and were found to produce improved failure detection times in eight of those twelve compared to the current engine safety monitoring system. Of the eight detected anomalous test firings, the first algorithm detected all eight, while the second algorithm detected seven of the eight. No false alarms were indicated by either algorithm for twelve nominal test firings. An initial parametric study of these algorithms for optimized parameter selection is presented and algorithm robustness to sensor failure is demonstrated.

  9. Supplement to safety analysis report. 306-W building operations safety requirement

    Microsoft Academic Search

    Richey

    1979-01-01

    The operations safety requirements (OSRs) presented in this report define the conditions, safe boundaries, and management control needed for safely conducting operations with radioactive materials in the Pacific Northwest Laboratory (PNL) 306-W building. The safety requirements are organized in five sections. Safety limits are safety-related process variables that are observable and measurable. Limiting conditions cover: equipment and technical conditions and

  10. Idaho National Engineering Laboratory (INEL) Environmental Restoration Program (ERP), Baseline Safety Analysis File (BSAF). Revision 1

    SciTech Connect

    Not Available

    1994-06-20

    This document was prepared to take the place of a Safety Evaluation Report since the Baseline Safety Analysis File (BSAF)and associated Baseline Technical Safety Requirements (TSR) File do not meet the requirements of a complete safety analysis documentation. Its purpose is to present in summary form the background of how the BSAF and Baseline TSR originated and a description of the process by which it was produced and approved for use in the Environmental Restoration Program.The BSAF is a facility safety reference document for INEL environmental restoration activities including environmental remediation of inactive waste sites and decontamination and decommissioning (D&D) of surplus facilities. The BSAF contains safety bases common to environmental restoration activities and guidelines for performing and documenting safety analysis. The common safety bases can be incorporated by reference into the safety analysis documentation prepared for individual environmental restoration activities with justification and any necessary revisions. The safety analysis guidelines in BSAF provide an accepted method for hazard analysis; analysis of normal, abnormal, and accident conditions; human factors analysis; and derivation of TSRS. The BSAF safety bases and guidelines are graded for environmental restoration activities.

  11. Network analysis reveals patterns behind air safety events

    NASA Astrophysics Data System (ADS)

    Zanin, Massimiliano

    2014-05-01

    Complex networks have been extensively used to study the topological and dynamical characteristics of transportation systems, although far less attention has been devoted to the analysis of specific problems arising in everyday operations. In this work, the use of a network representation is proposed for studying the appearance of Loss of Separation events, a kind of safety occurrence in which two aircraft violate the minimal separation while airborne. The topological analysis of networks representing the structure of traffic flows allows identifying situations in which the probability of appearance of such events is increased. Beyond these specific results, this work demonstrates the usefulness of the complex network approach in the analysis of operational patterns and occurrences.

  12. Safety Analysis of Soybean Processing for Advanced Life Support

    NASA Technical Reports Server (NTRS)

    Hentges, Dawn L.

    1999-01-01

    Soybeans (cv. Hoyt) is one of the crops planned for food production within the Advanced Life Support System Integration Testbed (ALSSIT), a proposed habitat simulation for long duration lunar/Mars missions. Soybeans may be processed into a variety of food products, including soymilk, tofu, and tempeh. Due to the closed environmental system and importance of crew health maintenance, food safety is a primary concern on long duration space missions. Identification of the food safety hazards and critical control points associated with the closed ALSSIT system is essential for the development of safe food processing techniques and equipment. A Hazard Analysis Critical Control Point (HACCP) model was developed to reflect proposed production and processing protocols for ALSSIT soybeans. Soybean processing was placed in the type III risk category. During the processing of ALSSIT-grown soybeans, critical control points were identified to control microbiological hazards, particularly mycotoxins, and chemical hazards from antinutrients. Critical limits were suggested at each CCP. Food safety recommendations regarding the hazards and risks associated with growing, harvesting, and processing soybeans; biomass management; and use of multifunctional equipment were made in consideration of the limitations and restraints of the closed ALSSIT.

  13. SCALE system cross-section validation for criticality safety analysis

    SciTech Connect

    Hathout, A.M.; Westfall, R.M.; Dodds, H.L. Jr.

    1980-01-01

    The purpose of this study is to test selected data from three cross-section libraries for use in the criticality safety analysis of UO/sub 2/ fuel rod lattices. The libraries, which are distributed with the SCALE system, are used to analyze potential criticality problems which could arise in the industrial fuel cycle for PWR and BWR reactors. Fuel lattice criticality problems could occur in pool storage, dry storage with accidental moderation, shearing and dissolution of irradiated elements, and in fuel transport and storage due to inadequate packing and shipping cask design. The data were tested by using the SCALE system to analyze 25 recently performed critical experiments.

  14. [The cascade scheme as a methodical platform for analysis of health risks in space flight and partially and fully analog conditions].

    PubMed

    Ushakov, I B; Poliakov, A V; Usov, V M

    2011-01-01

    Space anthropoecology, a subsection of human ecology, studies various aspects of physiological, psychological, social and professional adaptation to the extreme environment of space flight and human life and work in partially- and fully analogous conditions on Earth. Both SF and simulated extreme conditions are known for high human safety standards and a substantial analytic base that secures on-line analysis of torrent of information. Management evaluation and response to germing undesired developments aimed to curb their impact on the functioning of the crew-vehicle-environment system and human health involve the complete wealth of knowledge about risks to human health and performance. Spacecrew safety issues are tackled by experts of many specialties which emphasizes the importance of integral methodical approaches to risk estimation and mitigation, setting up barriers to adverse trends in human physiology and psychology in challenging conditions, and minimization of delayed effects on professional longevity and disorders in behavioral reactions. PMID:21970036

  15. Gaseous reduction of iron oxides: Part IV. mathematical analysis of partial internal reduction-diffusion control

    Microsoft Academic Search

    R. H. Tien; E. T. Turkdogan

    1972-01-01

    In this mathematical analysis of gaseous reduction of iron oxides, the partial internal reduction of the porous oxide and\\u000a gas diffusion in the porous iron layer are considered simultaneously in deriving the rate equation. The rate equation, derived\\u000a by partly analytical and partly numerical solutions, is well substantiated by the experimental results obtained previously.\\u000a The following parameters, determined previously, are

  16. A new technique for extracting partial discharge signals in on-line monitoring with wavelet analysis

    Microsoft Academic Search

    Mingyou Hu; Xiongwei Jiang; Hengkun Xie; Zhenhuai Wang

    1998-01-01

    This paper deals with the multiresolution analysis of wavelet transform for on-line partial discharge (PD) monitoring. One of the problems of PD on-line monitoring is how to suppress strong noises such as narrow-band radio frequency noise and random noise. In recent years, wavelet transform has become a powerful tool to analyze and process signals in various science and technology fields.

  17. A partial hybrid stress solid-shell element for the analysis of laminated composites

    Microsoft Academic Search

    K. Rah; W. Van Paepegem; A. M. Habraken; J. Degrieck

    2011-01-01

    In this paper we introduce a low order partial hybrid stress solid-shell element based on the composite energy functional for the analysis of laminated composite structures. This solid-shell element has eight nodes with only displacement degrees of freedoms, and three-dimensional constitutive models can be directly employed in the present formulation without any additional treatment. The assumed interlaminar stress field provides

  18. The prediction of soil carbon fractions using mid-infrared-partial least square analysis

    Microsoft Academic Search

    L. J. JanikA; L. R. SpouncerA

    This paper describes the application of mid-infrared (MIR) spectroscopy and partial least-squares (PLS) analysis to predict the concentration of organic carbon fractions present in soil. The PLS calibrations were derived from a standard set of soils that had been analysed for total organic carbon (TOC), particulate organic carbon (POC), and charcoal carbon (char-C) using physical and chemical means. PLS calibration

  19. Analysis of Iterative Line Spline Collocation Methods for Elliptic Partial Differential Equations

    Microsoft Academic Search

    A. Hadjidimos; E. N. Houstis; J. r. Rice E. Vavalis; E. Vavalis

    2000-01-01

    .In this paper we present the convergence analysis of iterative schemes for solving linear systemsresulting from discretizing multidimensional linear second order elliptic partial differential equations(PDEs) defined in ahyper-parallelepiped\\\\Omegaand subject to Dirichlet boundary conditions onsome facesof\\\\Omegaand Neumann on the others, using line cubic spline collocation (LCSC) methods.Specifically, we derive analytic expressions or obtain sharp bounds for the spectral radius of the...

  20. A geometrical formulation of the renormalization group method for global analysis II: Partial differential equations

    Microsoft Academic Search

    Teiji Kunihiro

    1997-01-01

    It is shown that the renormalization group (RG) method for global analysis can be formulated in the context of the classical\\u000a theory of envelopes: Several examples from partial differential equations are analyzed. The amplitude equations which are\\u000a usually derived by the reductive perturbation theory are shown to be naturally derived as the equations describing the envelopes\\u000a of the local solutions

  1. Limited-scope probabilistic safety analysis for the Los Alamos Meson Physics Facility (LAMPF)

    SciTech Connect

    Sharirli, M.; Rand, J.L.; Sasser, M.K.; Gallegos, F.R.

    1992-12-01

    The reliability of instrumentation and safety systems is a major issue in the operation of accelerator facilities. A probabilistic safety analysis was performed or the key safety and instrumentation systems at the Los Alamos Meson Physics Facility (LAMPF). in Phase I of this unique study, the Personnel Safety System (PSS) and the Current Limiters (XLs) were analyzed through the use of the fault tree analyses, failure modes and effects analysis, and criticality analysis. Phase II of the program was done to update and reevaluate the safety systems after the Phase I recommendations were implemented. This paper provides a brief review of the studies involved in Phases I and II of the program.

  2. Limited-scope probabilistic safety analysis for the Los Alamos Meson Physics Facility (LAMPF)

    SciTech Connect

    Sharirli, M.; Rand, J.L.; Sasser, M.K.; Gallegos, F.R.

    1992-01-01

    The reliability of instrumentation and safety systems is a major issue in the operation of accelerator facilities. A probabilistic safety analysis was performed or the key safety and instrumentation systems at the Los Alamos Meson Physics Facility (LAMPF). in Phase I of this unique study, the Personnel Safety System (PSS) and the Current Limiters (XLs) were analyzed through the use of the fault tree analyses, failure modes and effects analysis, and criticality analysis. Phase II of the program was done to update and reevaluate the safety systems after the Phase I recommendations were implemented. This paper provides a brief review of the studies involved in Phases I and II of the program.

  3. Upgraded safety analysis document including operations policies, operational safety limits and policy changes. Revision 2

    SciTech Connect

    Batchelor, K.

    1996-03-01

    The National Synchrotron Light Source Safety Analysis Reports (1), (2), (3), BNL reports {number_sign}51584, {number_sign}52205 and {number_sign}52205 (addendum) describe the basic Environmental Safety and Health issues associated with the department`s operations. They include the operating envelope for the Storage Rings and also the rest of the facility. These documents contain the operational limits as perceived prior or during construction of the facility, much of which still are appropriate for current operations. However, as the machine has matured, the experimental program has grown in size, requiring more supervision in that area. Also, machine studies have either verified or modified knowledge of beam loss modes and/or radiation loss patterns around the facility. This document is written to allow for these changes in procedure or standards resulting from their current mode of operation and shall be used in conjunction with the above reports. These changes have been reviewed by NSLS and BNL ES and H committee and approved by BNL management.

  4. Safety.

    ERIC Educational Resources Information Center

    Education in Science, 1996

    1996-01-01

    Discusses safety issues in science, including: allergic reactions to peanuts used in experiments; explosions in lead/acid batteries; and inspection of pressure vessels, such as pressure cookers or model steam engines. (MKR)

  5. PHYSICS AND SAFETY ANALYSIS FOR THE NIST RESEARCH REACTOR.

    SciTech Connect

    Cheng, L.; Diamond, D.; Xu, J.; Carew, J.; Rorer, D.

    2004-03-31

    Detailed reactor physics and safety analyses have been performed for the 20 MW D{sub 2}O moderated research reactor (NBSR) at the National Institute of Standards and Technology (NIST). The analyses provide an update to the Final Safety Analysis Report (FSAR) and employ state-of-the-art calculational methods. Three-dimensional Monte Carlo neutron and photon transport calculations were performed with the MCNP code to determine the safety parameters for the NBSR. The core depletion and determination of the fuel compositions were performed with MONTEBURNS. MCNP calculations were performed to determine the beginning, middle, and end-of-cycle power distributions, moderator temperature coefficient, and shim safety arm, beam tube and void reactivity worths. The calculational model included a plate-by-plate description of each fuel assembly, axial mid-plane water gap, beam tubes and the tubular geometry of the shim safety arms. The time-dependent analysis of the primary loop was determined with a RELAP5 transient analysis model that includes the pump, heat exchanger, fuel element geometry, and flow channels for both the six inner and twenty-four outer fuel elements. The statistical analysis used to assure protection from critical heat flux (CHF) was performed using a Monte Carlo simulation of the uncertainties contributing to the CHF calculation. The power distributions used to determine the local fuel conditions and margin to CHF were determined with MCNP. Evaluations were performed for the following accidents: (1) the control rod withdrawal startup accident, (2) the maximum reactivity insertion accident, (3) loss-of-flow resulting from loss of electrical power, (4) loss-of-flow resulting from a primary pump seizure, (5) loss-of-flow resulting from inadvertent throttling of a flow control valve, (6) loss-of-flow resulting from failure of both shutdown cooling pumps and (7) misloading of a fuel element. In both the startup and maximum reactivity insertion accidents, the core power transient is terminated by a reactor trip at 26 MW. The calculations show that both the peak reactor power and the excursion energy depend on the negative reactivity insertion from reactor trip. In one of the loss-of-flow accidents offsite electrical power is assumed lost to the three operating primary pumps. A slightly delayed reactor scram is initiated as a result of primary flow coast down. The RELAP5 results indicate that there is adequate margin to CHF and no damage to the fuel will occur, because of the momentum of the coolant flowing through the fuel channels and the negative scram reactivity insertion. For both the primary pump seizure and inadvertent throttling of a flow control valve, the RELAP5 analyses indicate that the reduction in power following the trip is sufficient to ensure that there is adequate margin to CHF and that the fuel cladding does not fail. The analysis of the loss-of-flow accident in the extremely unlikely case where both shutdown pumps fail, shows that the cooling provided by the D{sub 2}O is sufficient to ensure the cladding does not fail. The power distributions were examined for a set of fuel misloadings in which a fresh fuel element is moved from a peripheral low-reactivity location to a central high-reactivity location. The calculations show that there is adequate margin to CHF and the cladding does not fail. An additional analysis was performed to simulate the operation at low power (500 kW) without forced flow cooling. The result indicates that natural convection cooling is adequate for operation of the NBSR at a power level of 500 kW.

  6. Measurements of partial discharges by computer and analysis of partial discharge distribution by the Monte Carlo method

    Microsoft Academic Search

    M. Hikita; K. Yamada; A. Nakamura; T. Mizutani; A. Oohasi; M. Ieda

    1990-01-01

    The mechanism of partial discharge (PD) occurring in the CIGRE Method II (CM-II) electrode system, which is a representative closed-void model system is discussed in the context of a computer-aided PD measuring system. Measurements of PD are made for the CM-II electrode system. Effects of the pressure and gas inside the void on the PD are examined. Taking into account

  7. A Study on Urban Road Traffic Safety Based on Matter Element Analysis

    PubMed Central

    Hu, Qizhou; Zhou, Zhuping; Sun, Xu

    2014-01-01

    This paper examines a new evaluation of urban road traffic safety based on a matter element analysis, avoiding the difficulties found in other traffic safety evaluations. The issue of urban road traffic safety has been investigated through the matter element analysis theory. The chief aim of the present work is to investigate the features of urban road traffic safety. Emphasis was placed on the construction of a criterion function by which traffic safety achieved a hierarchical system of objectives to be evaluated. The matter element analysis theory was used to create the comprehensive appraisal model of urban road traffic safety. The technique was used to employ a newly developed and versatile matter element analysis algorithm. The matter element matrix solves the uncertainty and incompatibility of the evaluated factors used to assess urban road traffic safety. The application results showed the superiority of the evaluation model and a didactic example was included to illustrate the computational procedure. PMID:25587267

  8. Safety analysis of the GEM Detector Magnet conductor

    SciTech Connect

    Ferri, M.A.; Hassenzahl, W.V.

    1993-08-27

    The safety of the GEM Detector Magnet is analyzed using a computational model to determine current sharing between the cabled conductor and the external aluminum stabilizer. The model includes inductive and transverse conductive effects due to the geometries of the coil and the conductor. A conservative analysis indicates a peak conductor hotspot temperature of {approximately} 50 K at two seconds after the initiation of quench. After this time, additional heating is limited because most of the current in the normal zone region is carried by the aluminum stabilizer and an external protection circuit should have begun to diminish the total current. The analysis shows that conductor safety requires adequate transverse conductivity between the cable and the aluminum stabilizer. The calculated transverse conductance of the GEM conductor, 1 {times} 10{sup 7} mho/m, is at least 100 times greater than the minimum value necessary to limit the hotspot temperature to {approximately} 50 K after two seconds. This report describes the results of calculations based on a realistic assumption of GEM conductor performance during a quench.

  9. Partial wave analysis of the reaction gammap-->pomega and the search for nucleon resonances

    Microsoft Academic Search

    M. Williams; D. Applegate; M. Bellis; C. A. Meyer; K. P. Adhikari; M. Anghinolfi; H. Baghdasaryan; J. Ball; M. Battaglieri; I. Bedlinskiy; B. L. Berman; A. S. Biselli; W. J. Briscoe; W. K. Brooks; V. D. Burkert; S. L. Careccia; D. S. Carman; P. L. Cole; P. Collins; V. Crede; A. D'Angelo; A. Daniel; R. de Vita; E. de Sanctis; A. Deur; B. Dey; S. Dhamija; R. Dickson; C. Djalali; G. E. Dodge; D. Doughty; M. Dugger; R. Dupre; A. El Alaoui; L. Elouadrhiri; P. Eugenio; G. Fedotov; S. Fegan; A. Fradi; M. Y. Gabrielyan; M. Garçon; G. P. Gilfoyle; K. L. Giovanetti; F. X. Girod; W. Gohn; E. Golovatch; R. W. Gothe; K. A. Griffioen; M. Guidal; N. Guler; L. Guo; K. Hafidi; H. Hakobyan; C. Hanretty; N. Hassall; K. Hicks; M. Holtrop; Y. Ilieva; D. G. Ireland; B. S. Ishkhanov; E. L. Isupov; S. S. Jawalkar; H. S. Jo; J. R. Johnstone; K. Joo; D. Keller; M. Khandaker; P. Khetarpal; W. Kim; A. Klein; F. J. Klein; Z. Krahn; V. Kubarovsky; S. V. Kuleshov; V. Kuznetsov; K. Livingston; H. Y. Lu; M. Mayer; J. McAndrew; M. E. McCracken; B. McKinnon; M. Mirazita; V. Mokeev; B. Moreno; K. Moriya; B. Morrison; E. Munevar; P. Nadel-Turonski; C. S. Nepali; S. Niccolai; G. Niculescu; I. Niculescu; M. R. Niroula; R. A. Niyazov; M. Osipenko; A. I. Ostrovidov; E. Pasyuk; S. Anefalos Pereira; Y. Perrin; S. Pisano; O. Pogorelko; S. Pozdniakov; J. W. Price; S. Procureur; D. Protopopescu; G. Ricco; M. Ripani; B. G. Ritchie; G. Rosner; P. Rossi; F. Sabatié; M. S. Saini; J. Salamanca; C. Salgado; D. Schott; R. A. Schumacher; H. Seraydaryan; Y. G. Sharabian; E. S. Smith; D. I. Sober; D. Sokhan; S. S. Stepanyan; P. Stoler; I. I. Strakovsky; S. Strauch; M. Taiuti; D. J. Tedeschi; S. Tkachenko; M. Ungaro; M. F. Vineyard; E. Voutier; D. P. Watts; D. P. Weygand; M. H. Wood; J. Zhang; B. Zhao

    2009-01-01

    An event-based partial wave analysis (PWA) of the reaction gammap-->pomega has been performed on a high-statistics dataset obtained using the CLAS at Jefferson Lab for center-of-mass energies from threshold up to 2.4 GeV. This analysis benefits from access to the world's first high-precision spin-density matrix element measurements, available to the event-based PWA through the decay distribution of omega-->pi+pi-pi0. The data

  10. Deconvolution of variability and uncertainty in the Cassini safety analysis

    SciTech Connect

    Kampas, F.J. [Lockheed Martin Missiles and Space, P.O. Box 8555, Philadelphia, Pennsylvania 19101 (United States); Loughin, S. [WAM Systems, 650 Loraine Street, Ardmore, Pennsylvania 19003 (United States)

    1998-01-01

    The standard method for propagation of uncertainty in a risk analysis requires rerunning the risk calculation numerous times with model parameters chosen from their uncertainty distributions. This was not practical for the Cassini nuclear safety analysis, due to the computationally intense nature of the risk calculation. A less computationally intense procedure was developed which requires only two calculations for each accident case. The first of these is the standard {open_quotes}best-estimate{close_quotes} calculation. In the second calculation, variables and parameters change simultaneously. The mathematical technique of deconvolution is then used to separate out an uncertainty multiplier distribution, which can be used to calculate distribution functions at various levels of confidence. {copyright} {ital 1998 American Institute of Physics.}

  11. TESEC 2001, Genova, Italy ADVANCED TECHNIQUES FOR SAFETY ANALYSIS APPLIED TO

    E-print Network

    Tronci, Enrico

    for safety analysis of complex computer based systems. Such approaches are applied to the gas turbine control, Genova, Italy 2 safety functions to be implemented by the safety related system. As far as it concerns of the plant, due to instrumentation system failures. Another problem is in the current use of the different

  12. Safety Analysis of Requirements for a Product Family Robyn R. Lutz

    E-print Network

    Lutz, Robyn R.

    Safety Analysis of Requirements for a Product Family Robyn R. Lutz Iowa State University and Jet of the product family. Additional safety requirements for enhanced fault tolerance were derived from the completeness and robustness of a product family's safety-related software requirements. 1 Introduction

  13. Safety Analysis of Requirements for a Product Family Robyn R. Lutz \\Lambda

    E-print Network

    Lutz, Robyn R.

    Safety Analysis of Requirements for a Product Family Robyn R. Lutz \\Lambda Iowa State University an initial specification of the product family's required commonalities and variabili­ ties. The Safety was performed on representa­ tive members of the product family. Additional safety requirements for enhanced

  14. Formal safety analysis of mode transitions in aircraft flight control system

    Microsoft Academic Search

    B. Meenakshi; K. Das Barman; K. G. Babu; K. Sehgal

    2007-01-01

    Various well-established techniques exist for functional safety analysis of safety-critical avionics systems. Most of these techniques are based on informal models and due to this, analysis is often subjective and success is dependent on the skill of the practitioner. Various standards like DO-178B, IEC 61508 etc. that provide guidelines to perform safety analysis also propose formal verification methods as one

  15. Analysis of planetary exploration spacesuit systems and evaluation of a modified partial-gravity simulation technique

    NASA Astrophysics Data System (ADS)

    Chappell, Steven Patrick

    Building on prior experience during Apollo, NASA now plans to send humans back to the Moon and then on to Mars as part of its Vision for Space Exploration. An integral component for enabling this plan is the development of advanced spacesuit systems. A planetary exploration spacesuit system consists of an astronaut, a spacesuit, and the associated surface systems designed to enable completion of mission objectives. This thesis addresses all three aspects, beginning with an examination of the effects of locomotion stability in lunar and Mars gravity from a metabolic energy expenditure standpoint. An experiment to determine the effects of stability on running in reduced gravity was performed with a modified vertical offload partial gravity device. Operations scenarios were also developed, along with engineering analysis to understand the forces and moments involved in partial gravity locomotion. Analysis is presented to assess the applicability of terrestrial exploration systems and to adapt them for planetary exploration. Access systems for partial gravity planetary explorations are described that may allow humans in spacesuits to safely access scientifically significant terrain on the Moon and Mars. Contingency scenarios for effective rescue of astronauts from flat and sloped terrain were also analyzed. Conclusions and recommendations are offered regarding the effectiveness of the simulation technique developed. An Earth-based field testing program plan is presented with the intent of including access systems in the lunar surface system architecture requirements early enough to allow synergies in component design.

  16. Documented Safety Analysis for the B695 Segment

    SciTech Connect

    Laycak, D

    2008-09-11

    This Documented Safety Analysis (DSA) was prepared for the Lawrence Livermore National Laboratory (LLNL) Building 695 (B695) Segment of the Decontamination and Waste Treatment Facility (DWTF). The report provides comprehensive information on design and operations, including safety programs and safety structures, systems and components to address the potential process-related hazards, natural phenomena, and external hazards that can affect the public, facility workers, and the environment. Consideration is given to all modes of operation, including the potential for both equipment failure and human error. The facilities known collectively as the DWTF are used by LLNL's Radioactive and Hazardous Waste Management (RHWM) Division to store and treat regulated wastes generated at LLNL. RHWM generally processes low-level radioactive waste with no, or extremely low, concentrations of transuranics (e.g., much less than 100 nCi/g). Wastes processed often contain only depleted uranium and beta- and gamma-emitting nuclides, e.g., {sup 90}Sr, {sup 137}Cs, or {sup 3}H. The mission of the B695 Segment centers on container storage, lab-packing, repacking, overpacking, bulking, sampling, waste transfer, and waste treatment. The B695 Segment is used for storage of radioactive waste (including transuranic and low-level), hazardous, nonhazardous, mixed, and other waste. Storage of hazardous and mixed waste in B695 Segment facilities is in compliance with the Resource Conservation and Recovery Act (RCRA). LLNL is operated by the Lawrence Livermore National Security, LLC, for the Department of Energy (DOE). The B695 Segment is operated by the RHWM Division of LLNL. Many operations in the B695 Segment are performed under a Resource Conservation and Recovery Act (RCRA) operation plan, similar to commercial treatment operations with best demonstrated available technologies. The buildings of the B695 Segment were designed and built considering such operations, using proven building systems, and keeping them as simple as possible while complying with industry standards and institutional requirements. No operations to be performed in the B695 Segment or building system are considered to be complex. No anticipated future change in the facility mission is expected to impact the extent of safety analysis documented in this DSA.

  17. Risk analysis of highway traffic safety based on connection number and triangular fuzzy numbers

    Microsoft Academic Search

    Wang Mingwu; Chen Guangyi

    2010-01-01

    The risk analysis of highway traffic safety is a uncertainty system problem. Based on the theory of set pair analysis, stochastic simulation of triangular fuzzy numbers, herein a risk analysis model for the highway traffic safety was discussed. A concept of multi-element connection number of the set pair, which was consisted of evaluation index sets and classification standard sets of

  18. Detection of clustered gastrointestinal contractions in partial intestinal obstruction by surface vibration analysis.

    PubMed

    Cullen, P T; Storey, B E; Cuschieri, A; Campbell, F C

    1989-08-01

    Gastrointestinal contraction "clusters" with alternating quiescence occur in partial intestinal obstruction and are conventionally detected by intraluminal manometry. Surface Vibration Analysis (SVA), which is a noninvasive test, was evaluated in this study in experimental and clinical situations. In the experimental situation, former SVA was assessed against simultaneous manometry in two volunteers, in whom partial obstruction had been induced by intrajejunal balloon distension. Manometry showed typical contraction "clusters" with alternating quiescence, each of two to four minutes duration, in obstructed jejunum proximal to the balloon. The distal jejunum was inhibited. SVA showed a pattern of hyperactivity and quiescence corresponding to proximal jejunal activity. In the clinical situation, SVA recordings taken after a standard meal in nine patients with suspected chronic obstruction adhesive obstruction, (subsequently proven in seven patients and disproved in two), and 36 volunteers were compared. All patients with proved obstruction showed an SVA pattern of alternating hyperactivity and quiescence. This pattern was not observed in volunteers or nonobstructed patients. PMID:2757425

  19. Pion-nucleon partial wave analysis and study of baryon structure. Progress report, June 1, 1979-May 31, 1981

    SciTech Connect

    Hendrick, R.E.

    1981-01-10

    This report details progress toward completion of a long-term pion-nucleon partial wave analysis, summarizing results and conclusions to date. The report also discussed progress in using partial wave and resonance parameter results to test dynamical models of the baryon and in better understanding interquark forces within baryons.

  20. On the Consequences of Behavioral Adaptations in the Cost–Benefit Analysis of Road Safety Measures

    Microsoft Academic Search

    Olivier Gossner; Pierre Picard

    2005-01-01

    AbstractIt is sometimes argued that road safety measures or automobile safety standards fail to save lives because safer highways or safer cars induce more dangerous driving. A similar but less extreme view is that ignoring the behavioral adaptation of drivers would bias the cost–benefit analysis of a traffic safety measure. This article derives cost–benefit rules for automobile safety regulation when

  1. Detrended partial cross-correlation analysis of two nonstationary time series influenced by common external forces

    NASA Astrophysics Data System (ADS)

    Qian, Xi-Yuan; Liu, Ya-Min; Jiang, Zhi-Qiang; Podobnik, Boris; Zhou, Wei-Xing; Stanley, H. Eugene

    2015-06-01

    When common factors strongly influence two power-law cross-correlated time series recorded in complex natural or social systems, using detrended cross-correlation analysis (DCCA) without considering these common factors will bias the results. We use detrended partial cross-correlation analysis (DPXA) to uncover the intrinsic power-law cross correlations between two simultaneously recorded time series in the presence of nonstationarity after removing the effects of other time series acting as common forces. The DPXA method is a generalization of the detrended cross-correlation analysis that takes into account partial correlation analysis. We demonstrate the method by using bivariate fractional Brownian motions contaminated with a fractional Brownian motion. We find that the DPXA is able to recover the analytical cross Hurst indices, and thus the multiscale DPXA coefficients are a viable alternative to the conventional cross-correlation coefficient. We demonstrate the advantage of the DPXA coefficients over the DCCA coefficients by analyzing contaminated bivariate fractional Brownian motions. We calculate the DPXA coefficients and use them to extract the intrinsic cross correlation between crude oil and gold futures by taking into consideration the impact of the U.S. dollar index. We develop the multifractal DPXA (MF-DPXA) method in order to generalize the DPXA method and investigate multifractal time series. We analyze multifractal binomial measures masked with strong white noises and find that the MF-DPXA method quantifies the hidden multifractal nature while the multifractal DCCA method fails.

  2. Canister storage building (CSB) safety analysis report phase 3: Safety analysis documentation supporting CSB construction

    SciTech Connect

    Garvin, L.J.

    1997-04-28

    The Canister Storage Building (CSB) will be constructed in the 200 East Area of the U.S. Department of Energy (DOE) Hanford Site. The CSB will be used to stage and store spent nuclear fuel (SNF) removed from the Hanford Site K Basins. The objective of this chapter is to describe the characteristics of the site on which the CSB will be located. This description will support the hazard analysis and accident analyses in Chapter 3.0. The purpose of this report is to provide an evaluation of the CSB design criteria, the design's compliance with the applicable criteria, and the basis for authorization to proceed with construction of the CSB.

  3. Documented Safety Analysis for the Waste Storage Facilities

    SciTech Connect

    Laycak, D

    2008-06-16

    This documented safety analysis (DSA) for the Waste Storage Facilities was developed in accordance with 10 CFR 830, Subpart B, 'Safety Basis Requirements', and utilizes the methodology outlined in DOE-STD-3009-94, Change Notice 3. The Waste Storage Facilities consist of Area 625 (A625) and the Decontamination and Waste Treatment Facility (DWTF) Storage Area portion of the DWTF complex. These two areas are combined into a single DSA, as their functions as storage for radioactive and hazardous waste are essentially identical. The B695 Segment of DWTF is addressed under a separate DSA. This DSA provides a description of the Waste Storage Facilities and the operations conducted therein; identification of hazards; analyses of the hazards, including inventories, bounding releases, consequences, and conclusions; and programmatic elements that describe the current capacity for safe operations. The mission of the Waste Storage Facilities is to safely handle, store, and treat hazardous waste, transuranic (TRU) waste, low-level waste (LLW), mixed waste, combined waste, nonhazardous industrial waste, and conditionally accepted waste generated at LLNL (as well as small amounts from other DOE facilities).

  4. Documented Safety Analysis for the Waste Storage Facilities March 2010

    SciTech Connect

    Laycak, D T

    2010-03-05

    This Documented Safety Analysis (DSA) for the Waste Storage Facilities was developed in accordance with 10 CFR 830, Subpart B, 'Safety Basis Requirements,' and utilizes the methodology outlined in DOE-STD-3009-94, Change Notice 3. The Waste Storage Facilities consist of Area 625 (A625) and the Decontamination and Waste Treatment Facility (DWTF) Storage Area portion of the DWTF complex. These two areas are combined into a single DSA, as their functions as storage for radioactive and hazardous waste are essentially identical. The B695 Segment of DWTF is addressed under a separate DSA. This DSA provides a description of the Waste Storage Facilities and the operations conducted therein; identification of hazards; analyses of the hazards, including inventories, bounding releases, consequences, and conclusions; and programmatic elements that describe the current capacity for safe operations. The mission of the Waste Storage Facilities is to safely handle, store, and treat hazardous waste, transuranic (TRU) waste, low-level waste (LLW), mixed waste, combined waste, nonhazardous industrial waste, and conditionally accepted waste generated at LLNL (as well as small amounts from other DOE facilities).

  5. Hazard screening application guide. Safety Analysis Report Update Program

    SciTech Connect

    none,

    1992-06-01

    The basic purpose of hazard screening is to group precesses, facilities, and proposed modifications according to the magnitude of their hazards so as to determine the need for and extent of follow on safety analysis. A hazard is defined as a material, energy source, or operation that has the potential to cause injury or illness in human beings. The purpose of this document is to give guidance and provide standard methods for performing hazard screening. Hazard screening is applied to new and existing facilities and processes as well as to proposed modifications to existing facilities and processes. The hazard screening process evaluates an identified hazards in terms of the effects on people, both on-site and off-site. The process uses bounding analyses with no credit given for mitigation of an accident with the exception of certain containers meeting DOT specifications. The process is restricted to human safety issues only. Environmental effects are addressed by the environmental program. Interfaces with environmental organizations will be established in order to share information.

  6. Simplifying documentation while approaching site closure: integrated health & safety plans as documented safety analysis

    SciTech Connect

    Brown, Tulanda

    2003-06-01

    At the Fernald Closure Project (FCP) near Cincinnati, Ohio, environmental restoration activities are supported by Documented Safety Analyses (DSAs) that combine the required project-specific Health and Safety Plans, Safety Basis Requirements (SBRs), and Process Requirements (PRs) into single Integrated Health and Safety Plans (I-HASPs). By isolating any remediation activities that deal with Enriched Restricted Materials, the SBRs and PRs assure that the hazard categories of former nuclear facilities undergoing remediation remain less than Nuclear. These integrated DSAs employ Integrated Safety Management methodology in support of simplified restoration and remediation activities that, so far, have resulted in the decontamination and demolition (D&D) of over 150 structures, including six major nuclear production plants. This paper presents the FCP method for maintaining safety basis documentation, using the D&D I-HASP as an example.

  7. New Criticality Safety Analysis Capabilities in SCALE 5.1

    SciTech Connect

    Bowman, Stephen M [ORNL; DeHart, Mark D [ORNL; Dunn, Michael E [ORNL; Goluoglu, Sedat [ORNL; Horwedel, James E [ORNL; Petrie Jr, Lester M [ORNL; Rearden, Bradley T [ORNL; Williams, Mark L [ORNL

    2007-01-01

    Version 5.1 of the SCALE computer software system developed at Oak Ridge National Laboratory, released in 2006, contains several significant enhancements for nuclear criticality safety analysis. This paper highlights new capabilities in SCALE 5.1, including improved resonance self-shielding capabilities; ENDF/B-VI.7 cross-section and covariance data libraries; HTML output for KENO V.a; analytical calculations of KENO-VI volumes with GeeWiz/KENO3D; new CENTRMST/PMCST modules for processing ENDF/B-VI data in TSUNAMI; SCALE Generalized Geometry Package in NEWT; KENO Monte Carlo depletion in TRITON; and plotting of cross-section and covariance data in Javapeno.

  8. Issues related to criticality safety analysis for burnup credit applications

    SciTech Connect

    DeHart, M.D.; Parks, C.V.

    1995-12-01

    Spent fuel transportation and storage cask designs based on a burnup credit approach must consider issues that are not relevant in casks designed under a fresh fuel loading assumption. Parametric analyses are required to characterize the importance of fuel assembly and fuel cycle parameters on spent fuel composition and reactivity. Numerical models are evaluated to determine the sensitivity of criticality safety calculations to modeling assumptions. This paper discusses the results of studies to determine the effect of two important modeling assumptions on the criticality analysis of pressurized-water reactor (PWR) spent fuel: (1) the effect of assumed burnup history (i.e., specific power during and time-dependent variations in operational power) during depletion calculations, and (2) the effect of axial burnup distributions on the neutron multiplication factor calculated for a three-dimensional (3-D) conceptual cask design.

  9. Numerical Analysis for Structural Safety Evaluation of Butterfly Valves

    NASA Astrophysics Data System (ADS)

    Shin, Myung-Seob; Yoon, Joon-Yong; Park, Han-Yung

    2010-06-01

    Butterfly valves are widely used in current industry to control the fluid flow. They are used for both on-off and throttling applications involving large flows at relatively low operating pressure especially in large size pipelines. For the industrial application of butterfly valves, it must be ensured that the valve could be used safety under the fatigue life and the deformations produced by the pressure of the fluid. In this study, we carried out the structure analysis of the body and the valve disc of the butterfly valve and the numerical simulation was performed by using ANSYS v11.0. The reliability of valve is evaluated under the investigation of the deformation, the leak test and the durability of the valve.

  10. New Mathematical Derivations Applicable to Safety and Reliability Analysis

    SciTech Connect

    Cooper, J.A.; Ferson, S.

    1999-04-19

    Boolean logic expressions are often derived in safety and reliability analysis. Since the values of the operands are rarely exact, accounting for uncertainty with the tightest justifiable bounds is important. Accurate determination of result bounds is difficult when the inputs have constraints. One example of a constraint is that an uncertain variable that appears multiple times in a Boolean expression must always have the same value, although the value cannot be exactly specified. A solution for this repeated variable problem is demonstrated for two Boolean classes. The classes, termed functions with unate variables (including, but not limited to unate functions), and exclusive-or functions, frequently appear in Boolean equations for uncertain outcomes portrayed by logic trees (event trees and fault trees).

  11. 10 CFR 72.70 - Safety analysis report updating.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...FSAR; (2) All safety analyses and evaluations performed...48; (3) All final analyses and evaluations of the design and performance of structures, systems, and components...testing; and (4) All analyses of new safety...

  12. 10 CFR 72.70 - Safety analysis report updating.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...FSAR; (2) All safety analyses and evaluations performed...48; (3) All final analyses and evaluations of the design and performance of structures, systems, and components...testing; and (4) All analyses of new safety...

  13. 10 CFR 72.70 - Safety analysis report updating.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...FSAR; (2) All safety analyses and evaluations performed...48; (3) All final analyses and evaluations of the design and performance of structures, systems, and components...testing; and (4) All analyses of new safety...

  14. 10 CFR 72.70 - Safety analysis report updating.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...FSAR; (2) All safety analyses and evaluations performed...48; (3) All final analyses and evaluations of the design and performance of structures, systems, and components...testing; and (4) All analyses of new safety...

  15. 10 CFR 72.70 - Safety analysis report updating.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...FSAR; (2) All safety analyses and evaluations performed...48; (3) All final analyses and evaluations of the design and performance of structures, systems, and components...testing; and (4) All analyses of new safety...

  16. Planning Document for an NBSR Conversion Safety Analysis Report

    SciTech Connect

    Diamond D. J.; Baek J.; Hanson, A.L.; Cheng, L-Y.; Brown, N.; Cuadra, A.

    2013-09-25

    The NIST Center for Neutron Research (NCNR) is a reactor-laboratory complex providing the National Institute of Standards and Technology (NIST) and the nation with a world-class facility for the performance of neutron-based research. The heart of this facility is the National Bureau of Standards Reactor (NBSR). The NBSR is a heavy water moderated and cooled reactor operating at 20 MW. It is fueled with high-enriched uranium (HEU) fuel elements. A Global Threat Reduction Initiative (GTRI) program is underway to convert the reactor to low-enriched uranium (LEU) fuel. This program includes the qualification of the proposed fuel, uranium and molybdenum alloy foil clad in an aluminum alloy, and the development of the fabrication techniques. This report is a planning document for the conversion Safety Analysis Report (SAR) that would be submitted to, and approved by, the Nuclear Regulatory Commission (NRC) before the reactor could be converted.This report follows the recommended format and content from the NRC codified in NUREG-1537, “Guidelines for Preparing and Reviewing Applications for the Licensing of Non-power Reactors,” Chapter 18, “Highly Enriched to Low-Enriched Uranium Conversions.” The emphasis herein is on the SAR chapters that require significant changes as a result of conversion, primarily Chapter 4, Reactor Description, and Chapter 13, Safety Analysis. The document provides information on the proposed design for the LEU fuel elements and identifies what information is still missing. This document is intended to assist ongoing fuel development efforts, and to provide a platform for the development of the final conversion SAR. This report contributes directly to the reactor conversion pillar of the GTRI program, but also acts as a boundary condition for the fuel development and fuel fabrication pillars.

  17. Analysis of factors affecting the performance of partial nitrification in a sequencing batch reactor.

    PubMed

    Wei, Dong; Du, Bin; Xue, Xiaodong; Dai, Peng; Zhang, Jian

    2014-02-01

    The objective of this study was to analyze the factors affecting the performance of partial nitrification in a sequencing batch reactor. During a 140-day long-term operation, influent pH value, dissolved oxygen (DO), and chemical oxygen demand/nitrogen (COD/N) ratio were selected as operating factors to evaluate the maintenance and recovery of nitrite accumulation. Results showed that high DO concentration (2-4 mg/L) could damage nitrite accumulation immediately. However, nitrite accumulation ratio (NAR) could be increased from 1.68 ± 1.51 to 35.46 ± 7.86% when increasing the pH values from 7.5 to 8.3 due to the increased free ammonia concentration. Afterwards, stable partial nitrification and high NAR could be recovered when the reactor operated under low DO concentration (0.5-1.0 mg/L). However, it required a long time to recover the partial nitrification of the reactor when the influent COD/N ratios were altered. Fluorescence in situ hybridization analysis implied that ammonium oxidizing bacteria were completely recovered to the dominant nitrifying bacteria in the system. Meanwhile, sludge volumetric index of the reactor gradually decreased from 115.6 to 56.6 mL/g, while the mean diameter of sludge improved from 74.57 to 428.8 ?m by using the strategy of reducing settling time. The obtained results could provide useful information between the operational conditions and the performance of partial nitrification when treating nitrogen-rich industrial wastewater. PMID:23942879

  18. Comparative efficacy and safety of nimesulide and diclofenac in patients with acute shoulder, and a meta-analysis of controlled studies with nimesulide

    Microsoft Academic Search

    W. Wober

    1999-01-01

    Adverse events, particularly gastrointestinal, partially offset the therapeutic value of NSAIDs. The abilities of nimesulide to inhibit COX-2 preferentially and to exert other novel anti-inflammatory actions are consistent with good efficacy and safety. This is borne out by a double-blind multicentre comparison of nimesulide and diclofenac in 122 patients with acute shoulder, and by a meta-analysis of various nimesulide trials.

  19. Analysis of School Food Safety Programs Based on HACCP Principles

    ERIC Educational Resources Information Center

    Roberts, Kevin R.; Sauer, Kevin; Sneed, Jeannie; Kwon, Junehee; Olds, David; Cole, Kerri; Shanklin, Carol

    2014-01-01

    Purpose/Objectives: The purpose of this study was to determine how school districts have implemented food safety programs based on HACCP principles. Specific objectives included: (1) Evaluate how schools are implementing components of food safety programs; and (2) Determine foodservice employees food-handling practices related to food safety

  20. Safety Analysis of FMS/CTAS Interactions During Aircraft Arrivals

    NASA Technical Reports Server (NTRS)

    Leveson, Nancy G.

    1998-01-01

    This grant funded research on human-computer interaction design and analysis techniques, using future ATC environments as a testbed. The basic approach was to model the nominal behavior of both the automated and human procedures and then to apply safety analysis techniques to these models. Our previous modeling language, RSML, had been used to specify the system requirements for TCAS II for the FAA. Using the lessons learned from this experience, we designed a new modeling language that (among other things) incorporates features to assist in designing less error-prone human-computer interactions and interfaces and in detecting potential HCI problems, such as mode confusion. The new language, SpecTRM-RL, uses "intent" abstractions, based on Rasmussen's abstraction hierarchy, and includes both informal (English and graphical) specifications and formal, executable models for specifying various aspects of the system. One of the goals for our language was to highlight the system modes and mode changes to assist in identifying the potential for mode confusion. Three published papers resulted from this research. The first builds on the work of Degani on mode confusion to identify aspects of the system design that could lead to potential hazards. We defined and modeled modes differently than Degani and also defined design criteria for SpecTRM-RL models. Our design criteria include the Degani criteria but extend them to include more potential problems. In a second paper, Leveson and Palmer showed how the criteria for indirect mode transitions could be applied to a mode confusion problem found in several ASRS reports for the MD-88. In addition, we defined a visual task modeling language that can be used by system designers to model human-computer interaction. The visual models can be translated into SpecTRM-RL models, and then the SpecTRM-RL suite of analysis tools can be used to perform formal and informal safety analyses on the task model in isolation or integrated with the rest of the modeled system. We had hoped to be able to apply these modeling languages and analysis tools to a TAP air/ground trajectory negotiation scenario, but the development of the tools took more time than we anticipated.

  1. A review of the efficacy and safety of eslicarbazepine acetate in the management of partial-onset seizures.

    PubMed

    Rocamora, Rodrigo

    2015-07-01

    Eslicarbazepine acetate is a is a once-daily antiepileptic drug (AED) that was approved in 2009 by the European Medicines Agency (EMA) (Zebinix™), and in 2013 by the US Food and Drug Administration (FDA) (Aptiom™) as adjunctive therapy in adults with refractory partial-onset seizures, with or without secondary generalization. It is a third-generation member of the dibenzazepine family of AEDs with distinctive mechanism of action, posology and tolerability profile. The eslicarbazepine acetate development program included an initial phase II study (study BIA 2-093) and three subsequent phase III, multicentre, randomized, double-blinded and placebo-controlled clinical trials (studies BIA-2093-301, BIA- 2093-302 and BIA -2093-303). A fourth phase III placebo-controlled trial (study BIA-2093-304) was designed in order to meet specific requirements of the FDA. All performed studies have consistently shown that eslicarbazepine acetate (800 to 1200 mg/day) is effective and well tolerated as adjunctive therapy for adults with partial-onset seizures. PMID:26136845

  2. A review of the efficacy and safety of eslicarbazepine acetate in the management of partial-onset seizures

    PubMed Central

    2015-01-01

    Eslicarbazepine acetate is a is a once-daily antiepileptic drug (AED) that was approved in 2009 by the European Medicines Agency (EMA) (Zebinix™), and in 2013 by the US Food and Drug Administration (FDA) (Aptiom™) as adjunctive therapy in adults with refractory partial-onset seizures, with or without secondary generalization. It is a third-generation member of the dibenzazepine family of AEDs with distinctive mechanism of action, posology and tolerability profile. The eslicarbazepine acetate development program included an initial phase II study (study BIA 2-093) and three subsequent phase III, multicentre, randomized, double-blinded and placebo-controlled clinical trials (studies BIA-2093-301, BIA- 2093-302 and BIA -2093-303). A fourth phase III placebo-controlled trial (study BIA-2093-304) was designed in order to meet specific requirements of the FDA. All performed studies have consistently shown that eslicarbazepine acetate (800 to 1200 mg/day) is effective and well tolerated as adjunctive therapy for adults with partial-onset seizures. PMID:26136845

  3. Modeling and Analysis of Safety-Critical Cyber Physical Systems using State/Event Fault Trees

    E-print Network

    Paris-Sud XI, Université de

    Modeling and Analysis of Safety-Critical Cyber Physical Systems using State/Event Fault Trees state/event fault tree for modeling and analyzing the safety and the security aspects of CPSs. Keywords: reliability modeling, risk analysis, attack trees, fault tree, State/Event Fault Tree 1

  4. PHYSICS AND SAFETY ANALYSIS FOR THE NIST RESEARCH REACTOR.

    SciTech Connect

    Carew, J.; Hanson, A.; Xu, J.; Rorer, D.; Diamond, D.

    2003-08-26

    Detailed reactor physics and safety analyses have been performed for the 20 MW D{sub 2}O moderated research reactor (NBSR) at the National Institute of Standards and Technology (NIST). The analyses provide an update to the Final Safety Analysis Report (FSAR) and employ state-of-the-art calculational methods. Three-dimensional MCNP Monte Carlo neutron and photon transport calculations were performed to determine the safety parameters for the NBSR. The core depletion and determination of the fuel compositions were performed with MONTEBURNS. MCNP calculations were performed to determine the beginning, middle, and end-of-cycle power distributions, moderator temperature coefficient, and shim arm, beam tube and void reactivity worths. The calculational model included a plate-by-plate description of each fuel assembly, axial mid-plane water gap, beam tubes and the tubular geometry of the shim arms. The time-dependent analysis of the primary loop was determined with a RELAP5 transient analysis model including the pump, heat exchanger, fuel element geometry, and flow channels for both the six inner and twenty-four outer fuel elements. The statistical analysis used to assure protection from critical heat flux (CHF) was performed using a Monte Carlo simulation of the uncertainties contributing to the CHF calculation. The power distributions used to determine the local fuel conditions and margin to CHF were determined with MCNP. Evaluations were performed for the following accidents: (1) the control rod withdrawal startup accident, (2) the maximum reactivity insertion accident, (3) loss-of-flow resulting from loss of electrical power, (4) loss-of-flow resulting from a primary pump seizure, (5) loss-of-flow resulting from inadvertent throttling of a flow control valve, (6) loss-of-flow resulting from failure of both shutdown cooling pumps and (7) misloading of a fuel element. In both the startup and maximum reactivity insertion accidents, the core power transient is terminated by a reactor trip at 30 MW. The calculations show that both the peak reactor power and the excursion energy depend on the negative reactivity insertion from reactor trip. Two cases were considered for loss of electrical power. In the first case offsite power is lost, resulting in an immediate scram caused by loss of power to the control rod system. In the second case power is lost to only the three operating primary pumps, resulting in a slightly delayed scram when loss-of-flow is detected as the pumps coast down. In both instances, RELAP5 results indicate that there is adequate margin to CHF and no damage to the fuel will occur, because of the momentum of the coolant flowing through the fuel channels and the negative scram reactivity insertion. For both the primary pump seizure and inadvertent throttling of a flow control valve, the RELAP5 analyses indicate that the reduction in power following the trip is sufficient to ensure that there is adequate margin to CHF and the fuel cladding does not fail. The analysis of the loss-of-flow accident in the extremely unlikely case where both shutdown pumps fail shows that the cooling provided by the D{sub 2}O is sufficient to ensure the cladding does not fail. The power distributions were examined for a set of fuel misloadings in which a fresh fuel element is moved from a peripheral low-reactivity location to a central high-reactivity location. The calculations show that there is adequate margin to CHF and the cladding does not fail.

  5. Optimization of Lyapunov invariants in analysis and implementation of safety-critical software systems

    E-print Network

    Roozbehani, Mardavij

    2008-01-01

    This dissertation contributes to two major research areas in safety-critical software systems, namely, software analysis, and software implementation. In reference to the software analysis problem, the main contribution ...

  6. Lameness detection challenges in automated milking systems addressed with partial least squares discriminant analysis.

    PubMed

    Garcia, E; Klaas, I; Amigo, J M; Bro, R; Enevoldsen, C

    2014-12-01

    Lameness causes decreased animal welfare and leads to higher production costs. This study explored data from an automatic milking system (AMS) to model on-farm gait scoring from a commercial farm. A total of 88 cows were gait scored once per week, for 2 5-wk periods. Eighty variables retrieved from AMS were summarized week-wise and used to predict 2 defined classes: nonlame and clinically lame cows. Variables were represented with 2 transformations of the week summarized variables, using 2-wk data blocks before gait scoring, totaling 320 variables (2 × 2 × 80). The reference gait scoring error was estimated in the first week of the study and was, on average, 15%. Two partial least squares discriminant analysis models were fitted to parity 1 and parity 2 groups, respectively, to assign the lameness class according to the predicted probability of being lame (score 3 or 4/4) or not lame (score 1/4). Both models achieved sensitivity and specificity values around 80%, both in calibration and cross-validation. At the optimum values in the receiver operating characteristic curve, the false-positive rate was 28% in the parity 1 model, whereas in the parity 2 model it was about half (16%), which makes it more suitable for practical application; the model error rates were, 23 and 19%, respectively. Based on data registered automatically from one AMS farm, we were able to discriminate nonlame and lame cows, where partial least squares discriminant analysis achieved similar performance to the reference method. PMID:25282423

  7. Detrended Partial-Cross-Correlation Analysis: A New Method for Analyzing Correlations in Complex System

    PubMed Central

    Yuan, Naiming; Fu, Zuntao; Zhang, Huan; Piao, Lin; Xoplaki, Elena; Luterbacher, Juerg

    2015-01-01

    In this paper, a new method, detrended partial-cross-correlation analysis (DPCCA), is proposed. Based on detrended cross-correlation analysis (DCCA), this method is improved by including partial-correlation technique, which can be applied to quantify the relations of two non-stationary signals (with influences of other signals removed) on different time scales. We illustrate the advantages of this method by performing two numerical tests. Test I shows the advantages of DPCCA in handling non-stationary signals, while Test II reveals the “intrinsic” relations between two considered time series with potential influences of other unconsidered signals removed. To further show the utility of DPCCA in natural complex systems, we provide new evidence on the winter-time Pacific Decadal Oscillation (PDO) and the winter-time Nino3 Sea Surface Temperature Anomaly (Nino3-SSTA) affecting the Summer Rainfall over the middle-lower reaches of the Yangtze River (SRYR). By applying DPCCA, better significant correlations between SRYR and Nino3-SSTA on time scales of 6 ~ 8 years are found over the period 1951 ~ 2012, while significant correlations between SRYR and PDO on time scales of 35 years arise. With these physically explainable results, we have confidence that DPCCA is an useful method in addressing complex systems. PMID:25634341

  8. Detrended partial-cross-correlation analysis: a new method for analyzing correlations in complex system.

    PubMed

    Yuan, Naiming; Fu, Zuntao; Zhang, Huan; Piao, Lin; Xoplaki, Elena; Luterbacher, Juerg

    2015-01-01

    In this paper, a new method, detrended partial-cross-correlation analysis (DPCCA), is proposed. Based on detrended cross-correlation analysis (DCCA), this method is improved by including partial-correlation technique, which can be applied to quantify the relations of two non-stationary signals (with influences of other signals removed) on different time scales. We illustrate the advantages of this method by performing two numerical tests. Test I shows the advantages of DPCCA in handling non-stationary signals, while Test II reveals the "intrinsic" relations between two considered time series with potential influences of other unconsidered signals removed. To further show the utility of DPCCA in natural complex systems, we provide new evidence on the winter-time Pacific Decadal Oscillation (PDO) and the winter-time Nino3 Sea Surface Temperature Anomaly (Nino3-SSTA) affecting the Summer Rainfall over the middle-lower reaches of the Yangtze River (SRYR). By applying DPCCA, better significant correlations between SRYR and Nino3-SSTA on time scales of 6 ~ 8 years are found over the period 1951 ~ 2012, while significant correlations between SRYR and PDO on time scales of 35 years arise. With these physically explainable results, we have confidence that DPCCA is an useful method in addressing complex systems. PMID:25634341

  9. DNA Damage Focus Analysis in Blood Samples of Minipigs Reveals Acute Partial Body Irradiation

    PubMed Central

    Lamkowski, Andreas; Forcheron, Fabien; Agay, Diane; Ahmed, Emad A.; Drouet, Michel; Meineke, Viktor; Scherthan, Harry

    2014-01-01

    Radiation accidents frequently involve acute high dose partial body irradiation leading to victims with radiation sickness and cutaneous radiation syndrome that implements radiation-induced cell death. Cells that are not lethally hit seek to repair ionizing radiation (IR) induced damage, albeit at the expense of an increased risk of mutation and tumor formation due to misrepair of IR-induced DNA double strand breaks (DSBs). The response to DNA damage includes phosphorylation of histone H2AX in the vicinity of DSBs, creating foci in the nucleus whose enumeration can serve as a radiation biodosimeter. Here, we investigated ?H2AX and DNA repair foci in peripheral blood lymphocytes of Göttingen minipigs that experienced acute partial body irradiation (PBI) with 49 Gy (±6%) Co-60 ?-rays of the upper lumbar region. Blood samples taken 4, 24 and 168 hours post PBI were subjected to ?-H2AX, 53BP1 and MRE11 focus enumeration. Peripheral blood lymphocytes (PBL) of 49 Gy partial body irradiated minipigs were found to display 1–8 DNA damage foci/cell. These PBL values significantly deceed the high foci numbers observed in keratinocyte nuclei of the directly ?-irradiated minipig skin regions, indicating a limited resident time of PBL in the exposed tissue volume. Nonetheless, PBL samples obtained 4 h post IR in average contained 2.2% of cells displaying a pan-?H2AX signal, suggesting that these received a higher IR dose. Moreover, dispersion analysis indicated partial body irradiation for all 13 minipigs at 4 h post IR. While dose reconstruction using ?H2AX DNA repair foci in lymphocytes after in vivo PBI represents a challenge, the DNA damage focus assay may serve as a rapid, first line indicator of radiation exposure. The occurrence of PBLs with pan-?H2AX staining and of cells with relatively high foci numbers that skew a Poisson distribution may be taken as indicator of acute high dose partial body irradiation, particularly when samples are available early after IR exposure. PMID:24498326

  10. DNA damage focus analysis in blood samples of minipigs reveals acute partial body irradiation.

    PubMed

    Lamkowski, Andreas; Forcheron, Fabien; Agay, Diane; Ahmed, Emad A; Drouet, Michel; Meineke, Viktor; Scherthan, Harry

    2014-01-01

    Radiation accidents frequently involve acute high dose partial body irradiation leading to victims with radiation sickness and cutaneous radiation syndrome that implements radiation-induced cell death. Cells that are not lethally hit seek to repair ionizing radiation (IR) induced damage, albeit at the expense of an increased risk of mutation and tumor formation due to misrepair of IR-induced DNA double strand breaks (DSBs). The response to DNA damage includes phosphorylation of histone H2AX in the vicinity of DSBs, creating foci in the nucleus whose enumeration can serve as a radiation biodosimeter. Here, we investigated ?H2AX and DNA repair foci in peripheral blood lymphocytes of Göttingen minipigs that experienced acute partial body irradiation (PBI) with 49 Gy (± 6%) Co-60 ?-rays of the upper lumbar region. Blood samples taken 4, 24 and 168 hours post PBI were subjected to ?-H2AX, 53BP1 and MRE11 focus enumeration. Peripheral blood lymphocytes (PBL) of 49 Gy partial body irradiated minipigs were found to display 1-8 DNA damage foci/cell. These PBL values significantly deceed the high foci numbers observed in keratinocyte nuclei of the directly ?-irradiated minipig skin regions, indicating a limited resident time of PBL in the exposed tissue volume. Nonetheless, PBL samples obtained 4 h post IR in average contained 2.2% of cells displaying a pan-?H2AX signal, suggesting that these received a higher IR dose. Moreover, dispersion analysis indicated partial body irradiation for all 13 minipigs at 4 h post IR. While dose reconstruction using ?H2AX DNA repair foci in lymphocytes after in vivo PBI represents a challenge, the DNA damage focus assay may serve as a rapid, first line indicator of radiation exposure. The occurrence of PBLs with pan-?H2AX staining and of cells with relatively high foci numbers that skew a Poisson distribution may be taken as indicator of acute high dose partial body irradiation, particularly when samples are available early after IR exposure. PMID:24498326

  11. Interface design of VSOP'94 computer code for safety analysis

    SciTech Connect

    Natsir, Khairina, E-mail: yenny@batan.go.id; Andiwijayakusuma, D.; Wahanani, Nursinta Adi [Center for Development of Nuclear Informatics - National Nuclear Energy Agency, PUSPIPTEK, Serpong, Tangerang, Banten (Indonesia); Yazid, Putranto Ilham [Center for Nuclear Technology, Material and Radiometry- National Nuclear Energy Agency, Jl. Tamansari No.71, Bandung 40132 (Indonesia)

    2014-09-30

    Today, most software applications, also in the nuclear field, come with a graphical user interface. VSOP'94 (Very Superior Old Program), was designed to simplify the process of performing reactor simulation. VSOP is a integrated code system to simulate the life history of a nuclear reactor that is devoted in education and research. One advantage of VSOP program is its ability to calculate the neutron spectrum estimation, fuel cycle, 2-D diffusion, resonance integral, estimation of reactors fuel costs, and integrated thermal hydraulics. VSOP also can be used to comparative studies and simulation of reactor safety. However, existing VSOP is a conventional program, which was developed using Fortran 65 and have several problems in using it, for example, it is only operated on Dec Alpha mainframe platforms and provide text-based output, difficult to use, especially in data preparation and interpretation of results. We develop a GUI-VSOP, which is an interface program to facilitate the preparation of data, run the VSOP code and read the results in a more user friendly way and useable on the Personal 'Computer (PC). Modifications include the development of interfaces on preprocessing, processing and postprocessing. GUI-based interface for preprocessing aims to provide a convenience way in preparing data. Processing interface is intended to provide convenience in configuring input files and libraries and do compiling VSOP code. Postprocessing interface designed to visualized the VSOP output in table and graphic forms. GUI-VSOP expected to be useful to simplify and speed up the process and analysis of safety aspects.

  12. [Long-term animal experiment analysis of the use of resorbable staple sutures in partial gastrectomy].

    PubMed

    Walgenbach, S; Lang, U; Junginger, T

    1994-01-01

    In animal experiments with a 12-month follow-up, the safety and compatibility of absorbable staple lines following gastrointestinal surgery were analysed. In two groups of pigs, partial gastrectomies with gastroduodenostomy (Billroth I, n = 10) or gastrojejunostomy (Roux-en-Y, n = 12) were performed, and Lactomer-a copolymer of glycolic acid and lactic acid-staple lines were used for closure of the lesser curvature of the stomach and the duodenal stump. Application of the staple lines caused no problems and was safe. In 1 of the 22 pigs, which died of an ileus 9 days postoperatively a suture dehiscence (4.5%) at the lesser curvature of the stomach was observed. Macroscopic examination showed no major inflammation around the staples. Microscopically complete absorption of the Lactomer staples without extensive scarification in the gastrointestinal wall could be demonstrated 12 months postoperatively. Our results yielded no contraindications for the clinical use of absorbable staple lines in gastrointestinal surgery. The manufacturer has given advance notice of smaller staples, which it is considered will be an advantage. PMID:8145617

  13. Partial wave analysis of the reaction ?p?p? and the search for nucleon resonances

    NASA Astrophysics Data System (ADS)

    Williams, M.; Applegate, D.; Bellis, M.; Meyer, C. A.; Adhikari, K. P.; Anghinolfi, M.; Baghdasaryan, H.; Ball, J.; Battaglieri, M.; Bedlinskiy, I.; Berman, B. L.; Biselli, A. S.; Briscoe, W. J.; Brooks, W. K.; Burkert, V. D.; Careccia, S. L.; Carman, D. S.; Cole, P. L.; Collins, P.; Crede, V.; D'Angelo, A.; Daniel, A.; de Vita, R.; de Sanctis, E.; Deur, A.; Dey, B.; Dhamija, S.; Dickson, R.; Djalali, C.; Dodge, G. E.; Doughty, D.; Dugger, M.; Dupre, R.; Alaoui, A. El; Elouadrhiri, L.; Eugenio, P.; Fedotov, G.; Fegan, S.; Fradi, A.; Gabrielyan, M. Y.; Garçon, M.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Gohn, W.; Golovatch, E.; Gothe, R. W.; Griffioen, K. A.; Guidal, M.; Guler, N.; Guo, L.; Hafidi, K.; Hakobyan, H.; Hanretty, C.; Hassall, N.; Hicks, K.; Holtrop, M.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Isupov, E. L.; Jawalkar, S. S.; Jo, H. S.; Johnstone, J. R.; Joo, K.; Keller, D.; Khandaker, M.; Khetarpal, P.; Kim, W.; Klein, A.; Klein, F. J.; Krahn, Z.; Kubarovsky, V.; Kuleshov, S. V.; Kuznetsov, V.; Livingston, K.; Lu, H. Y.; Mayer, M.; McAndrew, J.; McCracken, M. E.; McKinnon, B.; Mirazita, M.; Mokeev, V.; Moreno, B.; Moriya, K.; Morrison, B.; Munevar, E.; Nadel-Turonski, P.; Nepali, C. S.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Niroula, M. R.; Niyazov, R. A.; Osipenko, M.; Ostrovidov, A. I.; Paris, M.; Park, K.; Park, S.; Pasyuk, E.; Pereira, S. Anefalos; Perrin, Y.; Pisano, S.; Pogorelko, O.; Pozdniakov, S.; Price, J. W.; Procureur, S.; Protopopescu, D.; Ricco, G.; Ripani, M.; Ritchie, B. G.; Rosner, G.; Rossi, P.; Sabatié, F.; Saini, M. S.; Salamanca, J.; Salgado, C.; Schott, D.; Schumacher, R. A.; Seraydaryan, H.; Sharabian, Y. G.; Smith, E. S.; Sober, D. I.; Sokhan, D.; Stepanyan, S. S.; Stoler, P.; Strakovsky, I. I.; Strauch, S.; Taiuti, M.; Tedeschi, D. J.; Tkachenko, S.; Ungaro, M.; Vineyard, M. F.; Voutier, E.; Watts, D. P.; Weygand, D. P.; Wood, M. H.; Zhang, J.; Zhao, B.

    2009-12-01

    An event-based partial wave analysis (PWA) of the reaction ?p?p? has been performed on a high-statistics dataset obtained using the CLAS at Jefferson Lab for center-of-mass energies from threshold up to 2.4 GeV. This analysis benefits from access to the world’s first high-precision spin-density matrix element measurements, available to the event-based PWA through the decay distribution of ???+?-?0. The data confirm the dominance of the t-channel ?0 exchange amplitude in the forward direction. The dominant resonance contributions are consistent with the previously identified states F15(1680) and D13(1700) near threshold, as well as the G17(2190) at higher energies. Suggestive evidence for the presence of a JP=5/2+ state around 2 GeV, a “missing” state, has also been found. Evidence for other states is inconclusive.

  14. Partial wave analysis of the reaction gamma p -> p omega$ and the search for nucleon resonances

    E-print Network

    M. Williams; D. Applegate; M. Bellis; C. A. Meyer; for the CLAS Collaboration

    2009-12-08

    An event-based partial wave analysis (PWA) of the reaction gamma p -> p omega has been performed on a high-statistics dataset obtained using the CLAS at Jefferson Lab for center-of-mass energies from threshold up to 2.4 GeV. This analysis benefits from access to the world's first high precision spin density matrix element measurements, available to the event-based PWA through the decay distribution of omega-> pi+ pi - pi0. The data confirm the dominance of the t-channel pi0 exchange amplitude in the forward direction. The dominant resonance contributions are consistent with the previously identified states F[15](1680) and D[13](1700) near threshold, as well as the G[17](2190) at higher energies. Suggestive evidence for the presence of a J(P)=5/2(+) state around 2 GeV, a "missing" state, has also been found. Evidence for other states is inconclusive.

  15. School Safety, Severe Disciplinary Actions, and School Characteristics: A Secondary Analysis of the School Survey on Crime and Safety

    ERIC Educational Resources Information Center

    Han, Seunghee; Akiba, Motoko

    2011-01-01

    On the basis of a secondary analysis of survey data collected from 1,872 secondary school principals in the 2005-2006 School Survey on Crime and Safety, we examined the frequency of and reasons for severe disciplinary actions and the relationship between school characteristics and severe disciplinary actions. We found that severe disciplinary…

  16. Heart rate changes in partial seizures: analysis of influencing factors among refractory patients

    PubMed Central

    2014-01-01

    Background We analyzed the frequency of heart rate (HR) changes related to seizures, and we sought to identify the influencing factors of these changes during partial seizures, to summarize the regularity of the HR changes and gain some insight into the mechanisms involved in the neuronal regulation of cardiovascular function. To date, detailed information on influencing factors of HR changes related to seizures by multiple linear regression analysis remains scarce. Methods Using video-electroencephalograph (EEG)-electrocardiograph (ECG) recordings, we retrospectively assessed the changes in the HR of 81 patients during a total of 181 seizures, including 27 simple partial seizures (SPS), 110 complex partial seizures (CPS) and 44 complex partial seizures secondarily generalized (CPS-G). The epileptogenic focus and the seizure type, age, gender, and sleep/wakefulness state of each patient were evaluated during and after the seizure onset. The HR changes were evaluated in the stage of epilepsy as time varies. Results Of the 181 seizures from 81 patients with ictal ECGs, 152 seizures (83.98%) from 74 patients were accompanied by ictal tachycardia (IT). And only 1 patient was accompanied by ictal bradycardia (IB). A patient has both IT and IB. We observed that HR difference was independently correlated with side, type and sleep/wakefulness state. In this analysis, the HR changes were related to the side, gender, seizure type, and sleep/wakefulness state. Right focus, male, sleep, and CPS-G showed more significant increases than that were observed in left, female, wakefulness, SPS and CPS. HR increases rapidly within 10 seconds before seizure onset and ictus, and typically slows to normal with seizure offset. Conclusion CPS-G, sleep and right focus led to higher ictal HR. The HR in the stage of epilepsy has regularly been observed to change to become time-varying. The risk factors of ictal HR need to be controlled along with sleep, CPS-G and right focus. Our study first explains that the HR in seizures has a regular evolution varying with time. Our study might help to further clarify the basic mechanisms of interactions between heart and brain, making seizure detection and closed-loop systems a possible therapeutic alternative in refractory patients. PMID:24950859

  17. Integration of partial least squares and Monte Carlo gene expression analysis in coronary artery disease

    PubMed Central

    ZHANG, HUAN; LI, TAO; WU, GUANJI; MA, FENG

    2014-01-01

    Coronary artery disease (CAD) is the most common type of cardiovascular disease and leading cause of mortality worldwide. Microarray technology for gene expression analysis has facilitated the identification of the molecular mechanism that underlies the pathogenesis of CAD. Previous studies have primarily used variance or regression analysis, without considering array specific factors. Thus, the aim of the present study was to investigate the mechanism of CAD using partial least squares (PLS)-based analysis, which was integrated with the Monte Carlo technique. Microarray analysis was performed with a data set of 110 CAD patients and 111 controls obtained from the Gene Expression Omnibus database. A total of 390 dysregulated genes were acquired. Significantly increased representations of dysregulated genes in Gene Ontology items, including transforming growth factor ?-activated receptor activity and acyl-CoA oxidase activity, were identified. Network analysis revealed three hub genes with a degree of >10, including ESR1, ITGA4 and ARRB2. The results of the present study provide novel information on the gene expression signatures of CAD patients and offer further theoretical support for future therapeutic study. PMID:24940402

  18. [Band depth analysis and partial least square regression based winter wheat biomass estimation using hyperspectral measurements].

    PubMed

    Fu, Yuan-Yuan; Wang, Ji-Hua; Yang, Gui-Jun; Song, Xiao-Yu; Xu, Xin-Gang; Feng, Hai-Kuan

    2013-05-01

    The major limitation of using existing vegetation indices for crop biomass estimation is that it approaches a saturation level asymptotically for a certain range of biomass. In order to resolve this problem, band depth analysis and partial least square regression (PLSR) were combined to establish winter wheat biomass estimation model in the present study. The models based on the combination of band depth analysis and PLSR were compared with the models based on common vegetation indexes from the point of view of estimation accuracy, subsequently. Band depth analysis was conducted in the visible spectral domain (550-750 nm). Band depth, band depth ratio (BDR), normalized band depth index, and band depth normalized to area were utilized to represent band depth information. Among the calibrated estimation models, the models based on the combination of band depth analysis and PLSR reached higher accuracy than those based on the vegetation indices. Among them, the combination of BDR and PLSR got the highest accuracy (R2 = 0.792, RMSE = 0.164 kg x m(-2)). The results indicated that the combination of band depth analysis and PLSR could well overcome the saturation problem and improve the biomass estimation accuracy when winter wheat biomass is large. PMID:23905343

  19. Idaho National Engineering Laboratory (INEL) Environmental Restoration (ER) Program Baseline Safety Analysis File (BSAF)

    SciTech Connect

    NONE

    1995-09-01

    The Baseline Safety Analysis File (BSAF) is a facility safety reference document for the Idaho National Engineering Laboratory (INEL) environmental restoration activities. The BSAF contains information and guidance for safety analysis documentation required by the U.S. Department of Energy (DOE) for environmental restoration (ER) activities, including: Characterization of potentially contaminated sites. Remedial investigations to identify and remedial actions to clean up existing and potential releases from inactive waste sites Decontamination and dismantlement of surplus facilities. The information is INEL-specific and is in the format required by DOE-EM-STD-3009-94, Preparation Guide for U.S. Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports. An author of safety analysis documentation need only write information concerning that activity and refer to BSAF for further information or copy applicable chapters and sections. The information and guidance provided are suitable for: {sm_bullet} Nuclear facilities (DOE Order 5480-23, Nuclear Safety Analysis Reports) with hazards that meet the Category 3 threshold (DOE-STD-1027-92, Hazard Categorization and Accident Analysis Techniques for Compliance with DOE Order 5480.23, Nuclear Safety Analysis Reports) {sm_bullet} Radiological facilities (DOE-EM-STD-5502-94, Hazard Baseline Documentation) Nonnuclear facilities (DOE-EM-STD-5502-94) that are classified as {open_quotes}low{close_quotes} hazard facilities (DOE Order 5481.1B, Safety Analysis and Review System). Additionally, the BSAF could be used as an information source for Health and Safety Plans and for Safety Analysis Reports (SARs) for nuclear facilities with hazards equal to or greater than the Category 2 thresholds, or for nonnuclear facilities with {open_quotes}moderate{close_quotes} or {open_quotes}high{close_quotes} hazard classifications.

  20. Providing Nuclear Criticality Safety Analysis Education through Benchmark Experiment Evaluation

    SciTech Connect

    John D. Bess; J. Blair Briggs; David W. Nigg

    2009-11-01

    One of the challenges that today's new workforce of nuclear criticality safety engineers face is the opportunity to provide assessment of nuclear systems and establish safety guidelines without having received significant experience or hands-on training prior to graduation. Participation in the International Criticality Safety Benchmark Evaluation Project (ICSBEP) and/or the International Reactor Physics Experiment Evaluation Project (IRPhEP) provides students and young professionals the opportunity to gain experience and enhance critical engineering skills.

  1. Packaging Review Guide for Reviewing Safety Analysis Reports for Packagings

    SciTech Connect

    DiSabatino, A; Biswas, D; DeMicco, M; Fisher, L E; Hafner, R; Haslam, J; Mok, G; Patel, C; Russell, E

    2007-04-12

    This Packaging Review Guide (PRG) provides guidance for Department of Energy (DOE) review and approval of packagings to transport fissile and Type B quantities of radioactive material. It fulfills, in part, the requirements of DOE Order 460.1B for the Headquarters Certifying Official to establish standards and to provide guidance for the preparation of Safety Analysis Reports for Packagings (SARPs). This PRG is intended for use by the Headquarters Certifying Official and his or her review staff, DOE Secretarial offices, operations/field offices, and applicants for DOE packaging approval. This PRG is generally organized at the section level in a format similar to that recommended in Regulatory Guide 7.9 (RG 7.9). One notable exception is the addition of Section 9 (Quality Assurance), which is not included as a separate chapter in RG 7.9. Within each section, this PRG addresses the technical and regulatory bases for the review, the manner in which the review is accomplished, and findings that are generally applicable for a package that meets the approval standards. This Packaging Review Guide (PRG) provides guidance for DOE review and approval of packagings to transport fissile and Type B quantities of radioactive material. It fulfills, in part, the requirements of DOE O 460.1B for the Headquarters Certifying Official to establish standards and to provide guidance for the preparation of Safety Analysis Reports for Packagings (SARPs). This PRG is intended for use by the Headquarters Certifying Official and his review staff, DOE Secretarial offices, operations/field offices, and applicants for DOE packaging approval. The primary objectives of this PRG are to: (1) Summarize the regulatory requirements for package approval; (2) Describe the technical review procedures by which DOE determines that these requirements have been satisfied; (3) Establish and maintain the quality and uniformity of reviews; (4) Define the base from which to evaluate proposed changes in scope and requirements of reviews; and (5) Provide the above information to DOE organizations, contractors, other government agencies, and interested members of the general public. This PRG was originally published in September 1987. Revision 1, issued in October 1988, added new review sections on quality assurance and penetrations through the containment boundary, along with a few other items. Revision 2 was published October 1999. Revision 3 of this PRG is a complete update, and supersedes Revision 2 in its entirety.

  2. Sodium fast reactor gaps analysis of computer codes and models for accident analysis and reactor safety

    Microsoft Academic Search

    Juan Carbajo; Hae-Yong Jeong; Roald Wigeland; Michael Corradini; Rodney Cannon Schmidt; Justin Thomas; Tom Wei; Tanju Sofu; Hans Ludewig; Yoshiharu Tobita; Hiroyuki Ohshima; Frederic Serre

    2011-01-01

    This report summarizes the results of an expert-opinion elicitation activity designed to qualitatively assess the status and capabilities of currently available computer codes and models for accident analysis and reactor safety calculations of advanced sodium fast reactors, and identify important gaps. The twelve-member panel consisted of representatives from five U.S. National Laboratories (SNL, ANL, INL, ORNL, and BNL), the University

  3. Preliminary safety analysis for the Chinese ITER Dual Functional Lithium-Lead Test Blanket Module

    NASA Astrophysics Data System (ADS)

    Chen, Hongli; Bai, Yunqing; Hu, Liqin; Chen, Mingliang; Song, Yong; Zeng, Qin; Liu, Songlin

    2009-07-01

    Safety analysis is part of the ITER Test Blanket Module (TBM) design process ensuring that the TBM does not adversely affect the safety of ITER. To get the licence for TBM as a whole with ITER, relevant safety analysis is required for each TBM system proposed by each party. The safety analysis for the Chinese Dual Functional Lithium-Lead Test Blanket Module (DFLL-TBM) has been performed based on the latest DFLL-TBM design. In this paper, the following safety considerations, such as source terms, operational releases, accident sequence analyses and waste assessment, were analysed. Both the deterministic approach and the complementary systematic approach starting with failure mode and effects analysis studies were adopted in the accidental analysis. The preliminary results showed that the DFLL-TBM system at normal operating conditions and under accident scenarios did not add additional safety hazards to the ITER machine and could meet the ITER safety requirements and additional safety requirements for the TBM system.

  4. Fast Flux Test Facility final safety analysis report. Amendment 72

    SciTech Connect

    Gantt, D.A.

    1992-08-01

    This document provides the Final Safety Analysis Report (FSAR) Amendment 72 for incorporation into the Fast Flux Test Facility (FFTF) FSAR set. This amendment change incorporates Engineering Change Notices issued subsequent to Amendment 71 and approved for incorporation before June 24, 1992. These include changes in: Chapter 2, Site Characteristics; Chapter 3, Design Criteria Structures, Equipment, and Systems; Chapter 5B, Reactor Coolant System; Chapter 7, Instrumentation and Control Systems; Chapter 8, Electrical Systems - The description of the Class 1E, 125 Vdc systems is updated for the higher capacity of the newly installed, replacement batteries; Chapter 9, Auxiliary Systems - The description of the inert cell NASA systems is corrected to list the correct number of spare sample points; Chapter 11, Reactor Refueling System; Chapter 12, Radiation Protection and Waste Management; Chapter 13, Conduct of Operations; Chapter 16, Quality Assurance; Chapter 17, Technical Specifications; Chapter 19, FFTF Fire Specifications for Fire Detection, Alarm, and Protection Systems; Chapter 20, FFTF Criticality Specifications; and Appendix B, Primary Piping Integrity Evaluation.

  5. Macroergonomics and patient safety: the impact of levels on theory, measurement, analysis and intervention in patient safety research.

    PubMed

    Karsh, Ben-Tzion; Brown, Roger

    2010-09-01

    The study and practice of patient safety has seen a surge over the last 10 years. New resident training and staffing policies, health information technologies, error reporting systems, team models of care, training methods, patient involvement, information handoff strategies, just cultures, and many other interventions have been mandated or attempted to improve the safety of patient care. While some of these interventions focus on individual providers and others focus on organization-level changes, little, if any, patient safety research has purposefully sought to understand how variables at different levels, such as the provider level or organization level, interact to impact patient safety outcomes such as errors, adverse drug events, or patient harm. Looking at relationships across levels is important because adverse events might be related to variables at different levels; consider that adverse events may be nested within patients, patients nested within nurses and physicians, nurses and physicians nested within shifts, shifts nested within hospital units, and so forth. Because these nested levels exist, they may exert as yet untested influence on the levels below. In this paper the impact of levels on theory, measurement, analysis and intervention in patient safety research is discussed. PMID:20153456

  6. A risk-informed approach to safety margins analysis

    SciTech Connect

    Curtis Smith; Diego Mandelli

    2013-07-01

    The Risk Informed Safety Margins Characterization (RISMC) Pathway is a systematic approach developed to characterize and quantify safety margins of nuclear power plant structures, systems and components. The model has been tested on the Advanced Test Reactor (ATR) at Idaho National Lab.

  7. Automation of System Safety Analysis: Possibilities and Pitfalls Andrew Galloway, University of York, Heslington, York YO10 5DD UK

    E-print Network

    Pumfrey, David

    Automation of System Safety Analysis: Possibilities and Pitfalls Andrew Galloway, University, York YO10 5DD UK Keywords: automated safety analysis, safety analysis tools Abstract As systems become where much of the complexity is found. To counter these problems there is growing demand for automation

  8. Nuclear criticality safety calculational analysis for small-diameter containers

    SciTech Connect

    LeTellier, M.S.; Smallwood, D.J.; Henkel, J.A. [and others

    1995-11-01

    This report documents calculations performed to establish a technical basis for the nuclear criticality safety of favorable geometry containers, sometimes referred to as 5-inch containers, in use at the Portsmouth Gaseous Diffusion Plant. A list of containers currently used in the plant is shown in Table 1.0-1. These containers are currently used throughout the plant with no mass limits. The use of containers with geometries or material types other than those addressed in this evaluation must be bounded by this analysis or have an additional analysis performed. The following five basic container geometries were modeled and bound all container geometries in Table 1.0-1: (1) 4.32-inch-diameter by 50-inch-high polyethylene bottle; (2) 5.0-inch-diameter by 24-inch-high polyethylene bottle; (3) 5.25-inch-diameter by 24-inch-high steel can ({open_quotes}F-can{close_quotes}); (4) 5.25-inch-diameter by 15-inch-high steel can ({open_quotes}Z-can{close_quotes}); and (5) 5.0-inch-diameter by 9-inch-high polybottle ({open_quotes}CO-4{close_quotes}). Each container type is evaluated using five basic reflection and interaction models that include single containers and multiple containers in normal and in credible abnormal conditions. The uranium materials evaluated are UO{sub 2}F{sub 2}+H{sub 2}O and UF{sub 4}+oil materials at 100% and 10% enrichments and U{sub 3}O{sub 8}, and H{sub 2}O at 100% enrichment. The design basis safe criticality limit for the Portsmouth facility is k{sub eff} + 2{sigma} < 0.95. The KENO study results may be used as the basis for evaluating general use of these containers in the plant.

  9. Fourier mode analysis of multigrid methods for partial differential equations with random coefficients

    SciTech Connect

    Seynaeve, Bert [Katholieke Universiteit Leuven, Department of Computer Science, Celestijnenlaan 200A, B-3001 Leuven (Belgium); Rosseel, Eveline [Katholieke Universiteit Leuven, Department of Computer Science, Celestijnenlaan 200A, B-3001 Leuven (Belgium); Nicolai, Bart [Katholieke Universiteit Leuven, Division of Mechatronics, Biostatistics and Sensors, Willem de Croylaan 42, B-3001 Leuven (Belgium); Vandewalle, Stefan [Katholieke Universiteit Leuven, Department of Computer Science, Celestijnenlaan 200A, B-3001 Leuven (Belgium)]. E-mail: Stefan.Vandewalle@cs.kuleuven.be

    2007-05-20

    Partial differential equations with random coefficients appear for example in reliability problems and uncertainty propagation models. Various approaches exist for computing the stochastic characteristics of the solution of such a differential equation. In this paper, we consider the spectral expansion approach. This method transforms the continuous model into a large discrete algebraic system. We study the convergence properties of iterative methods for solving this discretized system. We consider one-level and multi-level methods. The classical Fourier mode analysis technique is extended towards the stochastic case. This is done by taking the eigenstructure into account of a certain matrix that depends on the random structure of the problem. We show how the convergence properties depend on the particulars of the algorithm, on the discretization parameters and on the stochastic characteristics of the model. Numerical results are added to illustrate some of our theoretical findings.

  10. Partial-Wave Analysis of the Centrally Produced ?+?- System in pp Reactions at COMPASS

    E-print Network

    A. Austregesilo; T. Schlueter; for the COMPASS collaboration

    2012-07-05

    COMPASS is a fixed-target experiment at CERN SPS which investigates the structure and spectroscopy of hadrons. During nine weeks in 2008 and 2009, a 190 GeV/c proton beam impinging on a liquid hydrogen target was used in order to study the production of exotic mesons and glueball candidates at central rapidities. As no bias on the production mechanism was introduced by the trigger system, the contribution from diffractive dissociation of the beam proton poses a challenge. We select a centrally produced sample by kinematic cuts and introduce a model to describe the data in terms of partial waves. Preliminary fits are presented, which are consistent with results from previous experiments. Particular attention is paid to the ambiguities in the amplitude analysis of the two-pseudoscalar final state.

  11. Partial wave analysis of $?(2S) \\to p \\bar{p}?$

    E-print Network

    M. Ablikim; M. N. Achasov; O. Albayrak; D. J. Ambrose; F. F. An; Q. An; J. Z. Bai; R. Baldini Ferroli; Y. Ban; J. Becker; J. V. Bennett; N. Berger; M. Bertani; J. M. Bian; E. Boger; O. Bondarenko; I. Boyko; R. A. Briere; V. Bytev; H. Cai; X. Cai; O. Cakir; A. Calcaterra; G. F. Cao; S. A. Cetin; J. F. Chang; G. Chelkov; G. Chen; H. S. Chen; J. C. Chen; M. L. Chen; S. J. Chen; X. Chen; Y. B. Chen; H. P. Cheng; Y. P. Chu; D. Cronin-Hennessy; H. L. Dai; J. P. Dai; D. Dedovich; Z. Y. Deng; A. Denig; I. Denysenko; M. Destefanis; W. M. Ding; Y. Ding; L. Y. Dong; M. Y. Dong; S. X. Du; J. Fang; S. S. Fang; L. Fava; C. Q. Feng; P. Friedel; C. D. Fu; J. L. Fu; Y. Gao; C. Geng; K. Goetzen; W. X. Gong; W. Gradl; M. Greco; M. H. Gu; Y. T. Gu; Y. H. Guan; A. Q. Guo; L. B. Guo; T. Guo; Y. P. Guo; Y. L. Han; F. A. Harris; K. L. He; M. He; Z. Y. He; T. Held; Y. K. Heng; Z. L. Hou; C. Hu; H. M. Hu; J. F. Hu; T. Hu; G. M. Huang; G. S. Huang; J. S. Huang; L. Huang; X. T. Huang; Y. Huang; Y. P. Huang; T. Hussain; C. S. Ji; Q. Ji; Q. P. Ji; X. B. Ji; X. L. Ji; L. L. Jiang; X. S. Jiang; J. B. Jiao; Z. Jiao; D. P. Jin; S. Jin; F. F. Jing; N. Kalantar-Nayestanaki; M. Kavatsyuk; B. Kopf; M. Kornicer; W. Kuehn; W. Lai; J. S. Lange; M. Leyhe; C. H. Li; Cheng Li; Cui Li; D. M. Li; F. Li; G. Li; H. B. Li; J. C. Li; K. Li; Lei Li; Q. J. Li; S. L. Li; W. D. Li; W. G. Li; X. L. Li; X. N. Li; X. Q. Li; X. R. Li; Z. B. Li; H. Liang; Y. F. Liang; Y. T. Liang; G. R. Liao; X. T. Liao; D. Lin; B. J. Liu; C. L. Liu; C. X. Liu; F. H. Liu; Fang Liu; Feng Liu; H. Liu; H. B. Liu; H. H. Liu; H. M. Liu; H. W. Liu; J. P. Liu; K. Liu; K. Y. Liu; Kai Liu; P. L. Liu; Q. Liu; S. B. Liu; X. Liu; Y. B. Liu; Z. A. Liu; Zhiqiang Liu; Zhiqing Liu; H. Loehner; G. R. Lu; H. J. Lu; J. G. Lu; Q. W. Lu; X. R. Lu; Y. P. Lu; C. L. Luo; M. X. Luo; T. Luo; X. L. Luo; M. Lv; C. L. Ma; F. C. Ma; H. L. Ma; Q. M. Ma; S. Ma; T. Ma; X. Y. Ma; F. E. Maas; M. Maggiora; Q. A. Malik; Y. J. Mao; Z. P. Mao; J. G. Messchendorp; J. Min; T. J. Min; R. E. Mitchell; X. H. Mo; C. Morales Morales; N. Yu. Muchnoi; H. Muramatsu; Y. Nefedov; C. Nicholson; I. B. Nikolaev; Z. Ning; S. L. Olsen; Q. Ouyang; S. Pacetti; J. W. Park; M. Pelizaeus; H. P. Peng; K. Peters; J. L. Ping; R. G. Ping; R. Poling; E. Prencipe; M. Qi; S. Qian; C. F. Qiao; L. Q. Qin; X. S. Qin; Y. Qin; Z. H. Qin; J. F. Qiu; K. H. Rashid; G. Rong; X. D. Ruan; A. Sarantsev; B. D. Schaefer; M. Shao; C. P. Shen; X. Y. Shen; H. Y. Sheng; M. R. Shepherd; X. Y. Song; S. Spataro; B. Spruck; D. H. Sun; G. X. Sun; J. F. Sun; S. S. Sun; Y. J. Sun; Y. Z. Sun; Z. J. Sun; Z. T. Sun; C. J. Tang; X. Tang; I. Tapan; E. H. Thorndike; H. L. Tian; D. Toth; M. Ullrich; I. U. Uman; G. S. Varner; B. Q. Wang; D. Wang; D. Y. Wang; J. X. Wamg; K. Wang; L. L. Wang; L. S. Wang; M. Wang; P. Wang; P. L. Wang; Q. J. Wang; S. G. Wang; X. F. Wang; X. L. Wang; Y. D. Wang; Y. F. Wang; Y. Q. Wang; Z. Wang; Z. G. Wang; Z. Y. Wang; D. H. Wei; J. B. Wei; P. Weidenkaff; Q. G. Wen; S. P. Wen; M. Werner; U. Wiedner; L. H. Wu; N. Wu; S. X. Wu; W. Wu; Z. Wu; L. G. Xia; Y. X. Xia; Z. J. Xiao; Y. G. Xie; Q. L. Xiu; G. F. Xu; G. M. Xu; Q. J. Xu; Q. N. Xu; X. P. Xu; Z. R. Xu; F. Xue; Z. Xue; L. Yan; W. B. Yan; Y. H. Yan; H. X. Yang; Y. Yang; Y. X. Yang; H. Ye; M. Ye; M. H. Ye; B. X. Yu; C. X. Yu; H. W. Yu; J. S. Yu; S. P. Yu; C. Z. Yuan; Y. Yuan; A. A. Zafar; A. Zallo; Y. Zeng; B. X. Zhang; B. Y. Zhang; C. Zhang; C. C. Zhang; D. H. Zhang; H. H. Zhang; H. Y. Zhang; J. Q. Zhang; J. W. Zhang; J. Y. Zhang; J. Z. Zhang; Li Li Zhang; R. Zhang; S. H. Zhang; X. J. Zhang; X. Y. Zhang; Y. Zhang; Y. H. Zhang; Z. P. Zhang; Z. Y. Zhang; Zhenghao Zhang; G. Zhao; H. S. Zhao; J. W. Zhao; K. X. Zhao; Lei Zhao; Ling Zhao; M. G. Zhao; Q. Zhao; Q. Z. Zhao; S. J. Zhao; T. C. Zhao; X. H. Zhao; Y. B. Zhao; Z. G. Zhao; A. Zhemchugov; B. Zheng; J. P. Zheng; Y. H. Zheng; B. Zhong; Z. Zhong; L. Zhou; X. Zhou; X. K. Zhou; X. R. Zhou; C. Zhu; K. Zhu; K. J. Zhu; S. H. Zhu; X. L. Zhu; Y. C. Zhu; Y. M. Zhu; Y. S. Zhu; Z. A. Zhu; J. Zhuang; B. S. Zou; J. H. Zou

    2013-04-07

    Using a sample of $1.06 \\times 10^{8}$ $\\psi(2S)$ events collected with the BESIII detector at BEPCII, the decay $\\psi(2S) \\to p \\bar{p}\\eta$ is studied. A partial wave analysis determines that the intermediate state N(1535) with a mass of $1524\\pm5^{+10}_{-4}$ MeV/$c^2$ and a width of $130^{+27+57}_{-24-10}$ MeV/$c^2$ is dominant in the decay; the product branching fraction is determined to be $B(\\psi(2S) \\to N(1535)\\bar{p})\\times B(N(1535)\\to p\\eta)+c.c. = (5.2\\pm0.3^{+3.2}_{-1.2})\\times 10^{-5}$. Furthermore, the branching fraction of $\\psi(2S) \\to \\eta p \\bar{p}$ is measured to be $(6.4\\pm0.2\\pm0.6)\\times 10^{-5}$.

  12. Thermodynamic analysis and conceptual design for partial coal gasification air preheating coal-fired combined cycle

    NASA Astrophysics Data System (ADS)

    Xu, Yue; Wu, Yining; Deng, Shimin; Wei, Shirang

    2004-02-01

    The partial coal gasification air pre-heating coal-fired combined cycle (PGACC) is a cleaning coal power system, which integrates the coal gasification technology, circulating fluidized bed technology, and combined cycle technology. It has high efficiency and simple construction, and is a new selection of the cleaning coal power systems. A thermodynamic analysis of the PGACC is carried out. The effects of coal gasifying rate, pre-heating air temperature, and coal gas temperature on the performances of the power system are studied. In order to repower the power plant rated 100 MW by using the PGACC, a conceptual design is suggested. The computational results show that the PGACC is feasible for modernizing the old steam power plants and building the new cleaning power plants.

  13. Automated validation of patient safety clinical incident classification: macro analysis.

    PubMed

    Gupta, Jaiprakash; Patrick, Jon

    2013-01-01

    Patient safety is the buzz word in healthcare. Incident Information Management System (IIMS) is electronic software that stores clinical mishaps narratives in places where patients are treated. It is estimated that in one state alone over one million electronic text documents are available in IIMS. In this paper we investigate the data density available in the fields entered to notify an incident and the validity of the built in classification used by clinician to categories the incidents. Waikato Environment for Knowledge Analysis (WEKA) software was used to test the classes. Four statistical classifier based on J48, Naïve Bayes (NB), Naïve Bayes Multinominal (NBM) and Support Vector Machine using radial basis function (SVM_RBF) algorithms were used to validate the classes. The data pool was 10,000 clinical incidents drawn from 7 hospitals in one state in Australia. In first part of the study 1000 clinical incidents were selected to determine type and number of fields worth investigating and in the second part another 5448 clinical incidents were randomly selected to validate 13 clinical incident types. Result shows 74.6% of the cells were empty and only 23 fields had content over 70% of the time. The percentage correctly classified classes on four algorithms using categorical dataset ranged from 42 to 49%, using free-text datasets from 65% to 77% and using both datasets from 72% to 79%. Kappa statistic ranged from 0.36 to 0.4. for categorical data, from 0.61 to 0.74. for free-text and from 0.67 to 0.77 for both datasets. Similar increases in performance in the 3 experiments was noted on true positive rate, precision, F-measure and area under curve (AUC) of receiver operating characteristics (ROC) scores. The study demonstrates only 14 of 73 fields in IIMS have data that is usable for machine learning experiments. Irrespective of the type of algorithms used when all datasets are used performance was better. Classifier NBM showed best performance. We think the classifier can be improved further by reclassifying the most confused classes and there is scope to apply text mining tool on patient safety classifications. PMID:23823288

  14. An application of data envelopment analysis in telephone offices evaluation with partial data

    Microsoft Academic Search

    Soung-hie Kim; Choong-gyoo Park; Kyung-sam Park

    1999-01-01

    The presence of partial data motivates the need to investigate how such factors can be incorporated into the existing measurement models. In this paper, a procedure is proposed for incorporating a set of factors with partial data into the DEA structure and restricting factor weights. The first DEA formulation is a complicated non-linear model issued from the set of partial

  15. Reliability Modeling Methodology for Independent Approaches on Parallel Runways Safety Analysis

    NASA Technical Reports Server (NTRS)

    Babcock, P.; Schor, A.; Rosch, G.

    1998-01-01

    This document is an adjunct to the final report An Integrated Safety Analysis Methodology for Emerging Air Transport Technologies. That report presents the results of our analysis of the problem of simultaneous but independent, approaches of two aircraft on parallel runways (independent approaches on parallel runways, or IAPR). This introductory chapter presents a brief overview and perspective of approaches and methodologies for performing safety analyses for complex systems. Ensuing chapter provide the technical details that underlie the approach that we have taken in performing the safety analysis for the IAPR concept.

  16. Applying Adaptive Safety Analysis Techniques Robyn R. Lutz \\Lambda and HuiYin Shaw

    E-print Network

    Lutz, Robyn R.

    safety analysis techniques which have been used separately on software and hard­ ware into the system system needs. The technique was used on two recent space instruments: the Mars Microprobe Project software and system safety [9]. \\Lambda Proceedings of the Tenth International Symposium on Soft­ ware

  17. Design of a preliminary error impact analysis model for spatial safety assessment of earthmoving operations

    Microsoft Academic Search

    Seokho Chi; Carlos H. Caldas

    Regardless of technology benefits, safety planners still face difficulties explaining errors related to the use of different technologies and evaluating how the errors impact the performance of safety decision making. This paper presents a preliminary error impact analysis testbed to model object identification and tracking errors caused by image-based devices and algorithms and to analyze the impact of the errors

  18. Addressing Pedestrian Safety: A Content Analysis of Pedestrian Master Plans in North Carolina

    Microsoft Academic Search

    David K. Jones; Kelly R. Evenson; Daniel A. Rodriguez; Semra A. Aytur

    2010-01-01

    Objective: To systematically examine the content of pedestrian master plans in North Carolina in order to assess whether and how these plans were designed to improve pedestrian safety.Methods: All current pedestrian master plans in North Carolina through 2008 were gathered and examined using content analysis. A safety quality index was developed to assess the thoroughness with which a plan addressed

  19. Method for carrier aircraft task flow safety analysis based on TPN

    Microsoft Academic Search

    Zhaoguang Peng; Tingdi Zhao; Jin Tian

    2011-01-01

    With tight timing, sequencing and compact, the time error of any task flow activities of carrier aircrafts may result flow fracturing, leading to unsafe task. Currently, the research in the carrier aircraft safety is mainly focused on the quality of its flight dynamics modeling and simulation, while for carrier aircraft task flow analysis, its improvement, and safety induced by the

  20. In-space propellant systems safety. Volume 3: System safety analysis

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The primary objective was to examine from a system safety viewpoint in-space propellant logistic elements and operations to define the potential hazards and to recommend means to reduce, eliminate or control them. A secondary objective was to conduct trade studies of specific systems or operations to determine the safest of alternate approaches.

  1. Aspects of environmental and safety analysis of fusion reactors

    E-print Network

    Kazimi, Mujid S.

    1977-01-01

    This report summarizes the progress made between October 1976 and September 1977 in studies of some environmental and safety considerations in fusion reactor plants. A methodology to assess the admissible occurrence rate ...

  2. A semiotic analysis of biotechnology and food safety photographs 

    E-print Network

    Norwood, Jennifer Lynn

    2006-04-12

    This study evaluated photographs used in Time, Newsweek, and U.S. News and World Report in stories about biotechnology and food safety issues from the years 2000 and 2001. This study implemented a semiotic methodology to ...

  3. Reliability & Safety Analysis of a Fault-Tolerant Controller

    Microsoft Academic Search

    Barry W. Johnson; James H. Aylor

    1986-01-01

    This paper analyzes a fault-tolerant, microprocessor-based controller for an electric wheelchair. Two candidate architectures are considered, including reconfigurable duplication and stand-by sparing. The difference in the reliability and safety of the two candidates is determined through the use of Markov models. Safety is paramount in the wheelchair application because of the need to protect the physically disabled wheelchair user;reliability by

  4. Development of reload safety-analysis methodology and code package: uncertainty analysis. Final report. [PWR; BWR

    SciTech Connect

    Goldstein, R.

    1982-09-01

    This report presents the development of a statistical methodology proposed for use with the Electric Power Research Institute (EPRI) Reactor Analysis Support Package (RASP). The EPRI package is an integrated design methodology for use by utilities in reload core design, licensing, and operations support. Existing EPRI codes, including some currently under development, are major elements in the reload safety analysis methodology. As envisioned, the methodology will be applicable to both Pressurized Water Reactor (PWR) and Boiling Water Reactor (BWR) analyses. The current status of code development and availability has mandated that the scope of the present statistical effort be confined to a basic set of codes for the PWR analysis package. This consists of the neutronics (ARMP), systems analysis (RETRAN), and thermal-hydraulics (VIPRE) codes.

  5. New Methods and Tools to Perform Safety Analysis within RISMC

    SciTech Connect

    Diego Mandelli; Curtis Smith; Cristian Rabiti; Andrea Alfonsi; Robert Kinoshita; Joshua Cogliati

    2013-11-01

    The Risk Informed Safety Margins Characterization (RISMC) Pathway uses a systematic approach developed to characterize and quantify safety margins of nuclear power plant structures, systems and components. What differentiates the RISMC approach from traditional probabilistic risk assessment (PRA) is the concept of safety margin. In PRA, a safety metric such as core damage frequency (CDF) is generally estimated using static fault-tree and event-tree models. However, it is not possible to estimate how close we are to physical safety limits (say peak clad temperature) for most accident sequences described in the PRA. In the RISMC approach, what we want to understand is not just the frequency of an event like core damage, but how close we are (or not) to this event and how we might increase our safety margin through margin management strategies in a Dynamic PRA (DPRA) fashion. This paper gives an overview of methods that are currently under development at the Idaho National Laboratory (INL) with the scope of advance the current state of the art of dynamic PRA.

  6. A fully Bayesian before-after analysis of permeable friction course (PFC) pavement wet weather safety.

    PubMed

    Buddhavarapu, Prasad; Smit, Andre F; Prozzi, Jorge A

    2015-07-01

    Permeable friction course (PFC), a porous hot-mix asphalt, is typically applied to improve wet weather safety on high-speed roadways in Texas. In order to warrant expensive PFC construction, a statistical evaluation of its safety benefits is essential. Generally, the literature on the effectiveness of porous mixes in reducing wet-weather crashes is limited and often inconclusive. In this study, the safety effectiveness of PFC was evaluated using a fully Bayesian before-after safety analysis. First, two groups of road segments overlaid with PFC and non-PFC material were identified across Texas; the non-PFC or reference road segments selected were similar to their PFC counterparts in terms of site specific features. Second, a negative binomial data generating process was assumed to model the underlying distribution of crash counts of PFC and reference road segments to perform Bayesian inference on the safety effectiveness. A data-augmentation based computationally efficient algorithm was employed for a fully Bayesian estimation. The statistical analysis shows that PFC is not effective in reducing wet weather crashes. It should be noted that the findings of this study are in agreement with the existing literature, although these studies were not based on a fully Bayesian statistical analysis. Our study suggests that the safety effectiveness of PFC road surfaces, or any other safety infrastructure, largely relies on its interrelationship with the road user. The results suggest that the safety infrastructure must be properly used to reap the benefits of the substantial investments. PMID:25897515

  7. Partial Eval Partial Eval

    E-print Network

    Sumii, Eijiro

    Efficient Onl ine Partial E al ati n Eijiro Sumii o i o i i r i o o o umii o i u o o j #12; Partial/dynamic portions of p(sâ??,d) ¯ spec a e program p sâ?? (d) s p(sâ??,d) = = = = p sâ?? (d) or a am c pu d ope u e r . . . . -- -- -- . . #12; A Naive Onl ine Partial val at r E (expression) ::= x | l l l lx.E | E@E #12; A Naive Onl ine

  8. Distributed Control and Stochastic Analysis of Hybrid Systems Supporting Safety Critical Real-Time Systems Design

    E-print Network

    Del Moral , Pierre

    ................................................................................................................ 8 3. COMPOSITIONAL SPECIFICATION OF A PETRI NET MODEL ................................................ 12 4. PETRI NET MODEL OF FREE FLIGHT AIR TRAFFICDistributed Control and Stochastic Analysis of Hybrid Systems Supporting Safety Critical Real-Time

  9. Design and safety analysis of an in-flight, test airfoil 

    E-print Network

    McKnight, Christopher William

    2006-10-30

    The evaluation of an in-flight airfoil model requires extensive analysis of a variety of structural systems. Determining the safety of the design is a unique task dependant on the aircraft, flight environment, and physical requirements...

  10. Safety Analysis Report: X17B2 beamline Synchrotron Medical Research Facility

    SciTech Connect

    Gmuer, N.F.; Thomlinson, W.

    1990-02-01

    This report contains a safety analysis for the X17B2 beamline synchrotron medical research facility. Health hazards, risk assessment and building systems are discussed. Reference is made to transvenous coronary angiography. (LSP)

  11. The Oak Ridge Research Reactor: safety analysis: Volume 2, supplement 2

    SciTech Connect

    Hurt, S.S.

    1986-11-01

    The Oak Ridge Research Reactor Safety Analysis was last updated via ORNL-4169, Vol. 2, Supplement 1, in May of 1978. Since that date, several changes have been effected through the change-memo system described below. While these changes have involved the cooling system, the electrical system, and the reactor instrumentation and controls, they have not, for the most part, presented new or unreviewed safety questions. However, some of the changes have been based on questions or recommendations stemming from safety reviews or from reactor events at other sites. This paper discusses those changes which were judged to be safety related and which include revisions to the syphon-break system and changes related to seismic considerations which were very recently completed. The maximum hypothetical accident postulated in the original safety analysis requires dynamic containment and filtered flow for compliance with 10CFR100 limits at the site boundary.

  12. Object Oriented Safety Analysis of an Extra High Voltage Substation Bay

    Microsoft Academic Search

    Bartosz Nowicki; Janusz Górski

    1998-01-01

    Experiences of application of the object oriented approach to safety analysis of an extra high voltage substation bay are\\u000a presented. As the first step the object model of the whole application is developed. Then the model is subjected to three\\u000a safety analysis methods. The analyses are supported by an existing tool. The paper illustrates the application of the proposed\\u000a methods

  13. Epilepsy (partial)

    PubMed Central

    2011-01-01

    Introduction About 3% of people will be diagnosed with epilepsy during their lifetime, but about 70% of people with epilepsy eventually go into remission. Methods and outcomes We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of starting antiepileptic drug treatment following a single seizure? What are the effects of drug monotherapy in people with partial epilepsy? What are the effects of additional drug treatments in people with drug-resistant partial epilepsy? What is the risk of relapse in people in remission when withdrawing antiepileptic drugs? What are the effects of behavioural and psychological treatments for people with epilepsy? What are the effects of surgery in people with drug-resistant temporal lobe epilepsy? We searched: Medline, Embase, The Cochrane Library, and other important databases up to July 2009 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). Results We found 83 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. Conclusions In this systematic review we present information relating to the effectiveness and safety of the following interventions: antiepileptic drugs after a single seizure; monotherapy for partial epilepsy using carbamazepine, gabapentin, lamotrigine, levetiracetam, phenobarbital, phenytoin, sodium valproate, or topiramate; addition of second-line drugs for drug-resistant partial epilepsy (allopurinol, eslicarbazepine, gabapentin, lacosamide, lamotrigine, levetiracetam, losigamone, oxcarbazepine, retigabine, tiagabine, topiramate, vigabatrin, or zonisamide); antiepileptic drug withdrawal for people with partial or generalised epilepsy who are in remission; behavioural and psychological treatments for partial or generalised epilepsy (biofeedback, cognitive behavioural therapy (CBT), educational programmes, family counselling, relaxation therapy (alone or plus behavioural modification therapy, yoga); and surgery for drug-resistant temporal lobe epilepsy ( lesionectomy, temporal lobectomy, vagus nerve stimulation as adjunctive therapy). PMID:21549021

  14. Prospective Safety Analysis and the Complex Aviation System

    NASA Technical Reports Server (NTRS)

    Smith, Brian E.

    2013-01-01

    Fatal accident rates in commercial passenger aviation are at historic lows yet have plateaued and are not showing evidence of further safety advances. Modern aircraft accidents reflect both historic causal factors and new unexpected "Black Swan" events. The ever-increasing complexity of the aviation system, along with its associated technology and organizational relationships, provides fertile ground for fresh problems. It is important to take a proactive approach to aviation safety by working to identify novel causation mechanisms for future aviation accidents before they happen. Progress has been made in using of historic data to identify the telltale signals preceding aviation accidents and incidents, using the large repositories of discrete and continuous data on aircraft and air traffic control performance and information reported by front-line personnel. Nevertheless, the aviation community is increasingly embracing predictive approaches to aviation safety. The "prospective workshop" early assessment tool described in this paper represents an approach toward this prospective mindset-one that attempts to identify the future vectors of aviation and asks the question: "What haven't we considered in our current safety assessments?" New causation mechanisms threatening aviation safety will arise in the future because new (or revised) systems and procedures will have to be used under future contextual conditions that have not been properly anticipated. Many simulation models exist for demonstrating the safety cases of new operational concepts and technologies. However the results from such models can only be as valid as the accuracy and completeness of assumptions made about the future context in which the new operational concepts and/or technologies will be immersed. Of course that future has not happened yet. What is needed is a reasonably high-confidence description of the future operational context, capturing critical contextual characteristics that modulate both the likelihood of occurrence of hazards, and the likelihood that those hazards will lead to negative safety events. Heuristics extracted from scenarios, questionnaires, and observed trends from scanning the aviation horizon may be helpful in capturing those future changes in a way conducive to safety assessment. What is also needed is a checklist of potential sources of emerging risk that arise from organizational features that are frequently overlooked. The ultimate goal is to develop a pragmatic, workable method for using descriptions of the future aviation context, to generate valid predictions of safety risks.

  15. Macroergonomic analysis and design for improved safety and quality performance.

    PubMed

    Kleiner, B M

    1999-01-01

    Macroergonomics, which emerged historically after sociotechnical systems theory, quality management, and ergonomics, is presented as the basis for a needed integrative methodology. A macroergonomics methodology was presented in some detail to demonstrate how aspects of microergonomics, total quality management (TQM), and sociotechnical systems (STS) can be triangulated in a common approach. In the context of this methodology, quality and safety were presented as 2 of several important performance criteria. To demonstrate aspects of the methodology, 2 case studies were summarized with safety and quality performance results where available. The first case manipulated both personnel and technical factors to achieve a "safety culture" at a nuclear site. The concept of safety culture is defined in INSAG-4 (International Atomic Energy Agency, 1991). as "that assembly of characteristics and attitudes in organizations and individuals which establishes that, as an overriding priority, nuclear plant safety issues receive the attention warranted by their significance." The second case described a tire manufacturing intervention to improve quality (as defined by Sink and Tuttle, 1989) through joint consideration of technical and social factors. It was suggested that macroergonomics can yield greater performance than can be achieved through ergonomic intervention alone. Whereas case studies help to make the case, more rigorous formative and summative research is needed to refine and validate the proposed methodology respectively. PMID:10602647

  16. A system dynamics model for behavioral analysis of safety conditions in a chemical storage unit

    E-print Network

    Paris-Sud XI, Université de

    Mode Effect Analysis; Nicolet-Monnier, 1996), FTA (Fault Tree Analysis; Khan & Abbasi, 1998), FMECAA system dynamics model for behavioral analysis of safety conditions in a chemical storage unit.guarnieri@mines-paristech.fr Abstract This paper aims to develop a system dynamics model in order to formalize causal interdependencies

  17. Sodium fast reactor gaps analysis of computer codes and models for accident analysis and reactor safety.

    SciTech Connect

    Carbajo, Juan (Oak Ridge National Laboratory, Oak Ridge, TN); Jeong, Hae-Yong (Korea Atomic Energy Research Institute, Daejeon, Korea); Wigeland, Roald (Idaho National Laboratory, Idaho Falls, ID); Corradini, Michael (University of Wisconsin, Madison, WI); Schmidt, Rodney Cannon; Thomas, Justin (Argonne National Laboratory, Argonne, IL); Wei, Tom (Argonne National Laboratory, Argonne, IL); Sofu, Tanju (Argonne National Laboratory, Argonne, IL); Ludewig, Hans (Brookhaven National Laboratory, Upton, NY); Tobita, Yoshiharu (Japan Atomic Energy Agency, Ibaraki-ken, Japan); Ohshima, Hiroyuki (Japan Atomic Energy Agency, Ibaraki-ken, Japan); Serre, Frederic (Centre d'%C3%94etudes nucl%C3%94eaires de Cadarache %3CU%2B2013%3E CEA, France)

    2011-06-01

    This report summarizes the results of an expert-opinion elicitation activity designed to qualitatively assess the status and capabilities of currently available computer codes and models for accident analysis and reactor safety calculations of advanced sodium fast reactors, and identify important gaps. The twelve-member panel consisted of representatives from five U.S. National Laboratories (SNL, ANL, INL, ORNL, and BNL), the University of Wisconsin, the KAERI, the JAEA, and the CEA. The major portion of this elicitation activity occurred during a two-day meeting held on Aug. 10-11, 2010 at Argonne National Laboratory. There were two primary objectives of this work: (1) Identify computer codes currently available for SFR accident analysis and reactor safety calculations; and (2) Assess the status and capability of current US computer codes to adequately model the required accident scenarios and associated phenomena, and identify important gaps. During the review, panel members identified over 60 computer codes that are currently available in the international community to perform different aspects of SFR safety analysis for various event scenarios and accident categories. A brief description of each of these codes together with references (when available) is provided. An adaptation of the Predictive Capability Maturity Model (PCMM) for computational modeling and simulation is described for use in this work. The panel's assessment of the available US codes is presented in the form of nine tables, organized into groups of three for each of three risk categories considered: anticipated operational occurrences (AOOs), design basis accidents (DBA), and beyond design basis accidents (BDBA). A set of summary conclusions are drawn from the results obtained. At the highest level, the panel judged that current US code capabilities are adequate for licensing given reasonable margins, but expressed concern that US code development activities had stagnated and that the experienced user-base and the experimental validation base was decaying away quickly.

  18. Analysis of factors influencing safety management for metro construction in China.

    PubMed

    Yu, Q Z; Ding, L Y; Zhou, C; Luo, H B

    2014-07-01

    With the rapid development of urbanization in China, the number and size of metro construction projects are increasing quickly. At the same time, and increasing number of accidents in metro construction make it a disturbing focus of social attention. In order to improve safety management in metro construction, an investigation of the participants' perspectives on safety factors in China metro construction has been conducted to identify the key safety factors, and their ranking consistency among the main participants, including clients, consultants, designers, contractors and supervisors. The result of factor analysis indicates that there are five key factors which influence the safety of metro construction including safety attitude, construction site safety, government supervision, market restrictions and task unpredictability. In addition, ANOVA and Spearman rank correlation coefficients were performed to test the consistency of the means rating and the ranking of safety factors. The results indicated that the main participants have significant disagreement about the importance of safety factors on more than half of the items. Suggestions and recommendations on practical countermeasures to improve metro construction safety management in China are proposed. PMID:23932091

  19. Oak Ridge National Laboratory site data for safety-analysis report

    SciTech Connect

    Fitzpatrick, F.C.

    1982-12-01

    The Oak Ridge National Laboratory site data contained herein were compiled in support of the United States Department of Energy (USDOE) Oak Ridge Operations Office Order OR 5481.1. That order sets forth assignment of responsibilities for safety analysis and review responsibilities and provides guidance relative to the content and format of safety analysis reports. The information presented in this document is intended for use by reference in individual safety analysis reports where applicable to support accident analyses or the establishment of design bases of significance to safety, and it is applicable only to Oak Ridge National Laboratory facilities in Bethel and Melton Valleys. This information includes broad descriptions of the site characteristics, radioactive waste handling and monitoring practices, and the organization and operating policies at Oak Ridge National Laboratory. The historical background of the Laboratory is discussed briefly and the overall physical situation of the facilities is described in the following paragraphs.

  20. ACCIDENT ANALYSES & CONTROL OPTIONS IN SUPPORT OF THE SLUDGE WATER SYSTEM SAFETY ANALYSIS

    SciTech Connect

    WILLIAMS, J.C.

    2003-11-15

    This report documents the accident analyses and nuclear safety control options for use in Revision 7 of HNF-SD-WM-SAR-062, ''K Basins Safety Analysis Report'' and Revision 4 of HNF-SD-SNF-TSR-001, ''Technical Safety Requirements - 100 KE and 100 KW Fuel Storage Basins''. These documents will define the authorization basis for Sludge Water System (SWS) operations. This report follows the guidance of DOE-STD-3009-94, ''Preparation Guide for US. Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports'', for calculating onsite and offsite consequences. The accident analysis summary is shown in Table ES-1 below. While this document describes and discusses potential control options to either mitigate or prevent the accidents discussed herein, it should be made clear that the final control selection for any accident is determined and presented in HNF-SD-WM-SAR-062.

  1. Safety analysis of FFTF loss of flow without scram tests

    SciTech Connect

    Van Keuren, J.C.; Heard, F.J.; Stepnewski, D.D.

    1986-12-01

    Loss of flow without scram tests were conducted at the Fast Flux Test Facility (FFTF) in July of 1986 as part of the passive safety program. This paper describes the safety analyses that were conducted in preparation for these tests. The next two papers in this session will report results of the testing and give more details. These tests involved shutting off primary coolant flow with the reactor at powers of up to 200 MW or 50% of normal full power. PPS trips were bypassed prior to the test and additional trips installed. Consequently, a detailed reevaluation of PPS system and its response to off-normal events was required.

  2. Quantitative Analysis of Simulated Illicit Street-Drug Samples Using Raman Spectroscopy and Partial Least Squares Regression

    Microsoft Academic Search

    Owen S. Fenton; Lindsey A. Tonge; Taylor H. Moot; Kimberley A. Frederick

    2011-01-01

    Modern drug laws require that a seized sample be characterized for both the illegal substances present and the quantity of each of those substances. The goal of this work was to develop a common approach to model development based on Raman spectroscopic analysis followed by partial least squares (PLS) regression that would allow us to obtain quantitative information from simulated

  3. An Analysis of Cooperative Coevolutionary Algorithms A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor

    E-print Network

    Wiegand, R. Paul

    An Analysis of Cooperative Coevolutionary Algorithms A dissertation submitted in partial Services. They do a huge and irreplaceable service for those of us in deep study, and probably cannot to be among the many who say that life is an adventure of learning and for every question answered

  4. IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, VOL. X, NO. X, XXX 20XX 1 Partially Supervised Speaker Clustering

    E-print Network

    Hasegawa-Johnson, Mark

    IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, VOL. X, NO. X, XXX 20XX 1 Partially, audio, video, text, etc.), one significant goal being to associate the identity of the content, audio, video, text, etc.) so that the identity of the content (face, voice, keywords, etc.) can

  5. Mellin Transform Based Performance Analysis of FFH Mary FSK Using Product Combining Against Partial Band Noise Jamming

    Microsoft Academic Search

    Sohail Ahmed; Lie-liang Yang; Lajos Hanzo

    2007-01-01

    We propose a novel bit error ratio (BER) analysis technique for fast frequency hopping (FFH) assisted M-ary frequency shift keying (MFSK) using product combining (PC), when the channel is contaminated by partial band noise jamming (PBNJ). Exploiting the fact that the Mellin transform of the product of independent random variables is the product of their Mellin transforms, we derive the

  6. Zircon UPb chemical abrasion (bCA-TIMSQ) method: Combined annealing and multi-step partial dissolution analysis

    E-print Network

    Reiners, Peter W.

    Zircon U­Pb chemical abrasion (bCA-TIMSQ) method: Combined annealing and multi-step partial dissolution analysis for improved precision and accuracy of zircon ages James M. Mattinson Department-precision and high-accuracy U­Pb zircon geochronology is the total elimination of discordance caused by Pb loss

  7. [Application of calibration curve method and partial least squares regression analysis to quantitative analysis of nephrite samples using XRF].

    PubMed

    Liu, Song; Su, Bo-min; Li, Qing-hui; Gan, Fu-xi

    2015-01-01

    The authors tried to find a method for quantitative analysis using pXRF without solid bulk stone/jade reference samples. 24 nephrite samples were selected, 17 samples were calibration samples and the other 7 are test samples. All the nephrite samples were analyzed by Proton induced X-ray emission spectroscopy (PIXE) quantitatively. Based on the PIXE results of calibration samples, calibration curves were created for the interested components/elements and used to analyze the test samples quantitatively; then, the qualitative spectrum of all nephrite samples were obtained by pXRF. According to the PIXE results and qualitative spectrum of calibration samples, partial least square method (PLS) was used for quantitative analysis of test samples. Finally, the results of test samples obtained by calibration method, PLS method and PIXE were compared to each other. The accuracy of calibration curve method and PLS method was estimated. The result indicates that the PLS method is the alternate method for quantitative analysis of stone/jade samples. PMID:25993858

  8. Transverse earthquake response analysis of a seismically isolated regular bridge with partial restraint

    Microsoft Academic Search

    Meng-Hao Tsai

    2008-01-01

    Most of the seismically isolated bridges in Taiwan share a common feature in that both ends of the superstructures are restrained from transverse movement. They are defined as partially restrained seismically isolated (PRSI) bridges. From measured acceleration responses, effectiveness of the longitudinal seismic isolation of the PRSI bridges had been confirmed. Nevertheless, the seismic isolation behavior in the partially restrained

  9. Interpretation of wavelet analysis and its application in partial discharge detection

    Microsoft Academic Search

    X. Ma; Chengke Zhou; I. J. Kemp

    2002-01-01

    The objective of the paper is to discuss a tool which is proving extremely efficient in partial discharge measurement studies. Though the technique itself is not new, its application to partial discharge studies is. It will be demonstrated in this paper that it has tremendous power and this accounts for its rapid growth as an application in this field. The

  10. High frequency finite element analysis of electromagnetic radiation due to partial discharges in high voltage equipment

    Microsoft Academic Search

    S. Xiao; P. J. Moore; M. D. Judd; I. E. Portugues

    2008-01-01

    Measuring partial discharge (PD) activity in high voltage plant is a well established technique used to monitor insulation integrity. A partial discharge is a surge of electrons within a dielectric due to ionisation caused by the electric field and it is a sign of insulation degradation or overstressing. The acceleration of electrons creates electromagnetic radiation. This paper studies the high

  11. Continuous wavelet transform based partial least squares regression for quantitative analysis of Raman spectrum.

    PubMed

    Li, Shuo; Nyagilo, James O; Dave, Digant P; Gao, Jean X

    2013-09-01

    Quantitative analysis of Raman spectra using surface-enhanced Raman scattering (SERS) nanoparticles has shown the potential and promising trend of development in in vivo molecular imaging. Partial least square regression (PLSR) methods have been reported as state-of-the-art methods. However, the approaches fully rely on the intensities of Raman spectra and can not avoid the influences of the unstable background. In this paper we design a new continuous wavelet transform based PLSR (CWT-PLSR) algorithm that uses mixing concentrations and the average CWT coefficients of Raman spectra to carry out PLSR. We elaborate and prove how the average CWT coefficients with a Mexican hat mother wavelet are robust representations of Raman peaks, and the method can reduce the influences of unstable baseline and random noises during the prediction process. The algorithm was tested using three Raman spectra data sets with three cross-validation methods in comparison with current leading methods, and the results show its robustness and effectiveness. PMID:23963247

  12. Application of phasor measurements and partial energy analysis in stabilizing large disturbances

    SciTech Connect

    Stanton, S.E. [Stanton Engineering Services, Cascade, ID (United States)] [Stanton Engineering Services, Cascade, ID (United States); Slivinsky, C. [Univ. of Missouri, Columbia, MO (United States). Electrical Engineering Dept.] [Univ. of Missouri, Columbia, MO (United States). Electrical Engineering Dept.; Martin, K.; Nordstrom, J. [Bonneville Power Administration, Portland, OR (United States)] [Bonneville Power Administration, Portland, OR (United States)

    1995-02-01

    Precise time-synchronized phasor measurements are available to us today from the Phasor Measurement Unit (PMU). One of the most promising uses of the PMU is for during-transient control applications. The work reported in this paper investigated the ability of synchronized Phase Angle Measurements to identify impending instabilities through real time measurements, and to trigger remedial actions in time to prevent major power system outages. At question was feasibility and how many additional Megawatts could be transferred when using the PMU to arm existing during-transient controllers. The Partial Energy Function is defined and explained symbolically in terms of Kimbark`s equal area criterion and power-angle diagrams. The four steps for accomplishing PMU based detection of instability are outlined. The approach is applied to instability conditions in Bonneville Power`s 500 kV transmission network West of Colstrip, MO. The effectiveness of the improved remedial action is demonstrated in terms of energy analysis and Kimbark diagrams and reported in terms of Megawatts of increased power transfer.

  13. Breakpoint analysis of Turner patients with partial Xp deletions: implications for the lymphoedema gene location

    PubMed Central

    Boucher, C.; Sargent, C.; Ogata, T.; Affara, N.

    2001-01-01

    BACKGROUND—Turner syndrome is characterised by a 45,X karyotype and a variety of skeletal, lymphoedemic, and gonadal anomalies. Genes involved in the Turner phenotype are thought to be X/Y homologous with the X genes escaping X inactivation. Haploinsufficiency of the SHOX gene has been reported to cause the short stature seen in Turner syndrome patients. More recently, mutations of this gene have been shown to be associated with other skeletal abnormalities, suggesting that haploinsufficiency of SHOX causes all the Turner skeletal anomalies. No such gene has yet been identified for the lymphoedemic features.?METHODS—Fluorescence in situ hybridisation (FISH) analysis with PAC clones on nine patients with partially deleted X chromosomes was performed.?RESULTS/DISCUSSION—The Turner syndrome stigmata for each patient are described and correlation between the breakpoint and the phenotype discussed. A lymphoedema critical region in Xp11.4 is proposed and its gene content discussed with respect to that in the previously reported Yp11.2 lymphoedema critical region.???Keywords: Turner syndrome; lymphoedema; Xp11.4 PMID:11546827

  14. Stability analysis of partially loaded Leipholz column carrying a lumped mass and resting on elastic foundation

    NASA Astrophysics Data System (ADS)

    Fazelzadeh, S. A.; Kazemi-Lari, M. A.

    2013-02-01

    In the present study, the stability of a cantilever column resting on an elastic foundation under the action of a uniformly distributed tangential load is discussed. A Winkler type elastic foundation is considered. Moreover, the effect of a lumped mass located in an arbitrary position on the stability of the system when the column is subjected to a partially distributed follower force is investigated. The equations of motion are obtained using the extended Hamilton's principle and the influences of the lumped mass and applied load are included in the equations using the generalized functions theories. Applying the Ritz technique, the resulting equations are transformed into a general eigenvalue problem. The effects of several design parameters such as foundation elastic modulus, ratio of the lumped mass to the column's mass, position of the lumped mass and the distribution model of the follower force are examined. The validity of the present analysis is confirmed by comparing the results with those obtained in literature and excellent agreement is observed. The numerical results reveal that the load distribution length and model have significant effects on the flutter boundaries of the system.

  15. Thread safety in an MPI implementation : requirements and analysis.

    SciTech Connect

    Gropp, W.; Thakur, R.; Mathematics and Computer Science

    2007-09-01

    The MPI-2 Standard has carefully specified the interaction between MPI and user-created threads. The goal of this specification is to allow users to write multithreaded MPI programs while also allowing MPI implementations to deliver high performance. However, a simple reading of the thread-safety specification does not reveal what its implications are for an implementation and what implementers must be aware (and careful) of. In this paper, we describe and analyze what the MPI Standard says about thread-safety and what it implies for an implementation. We classify the MPI functions based on their thread-safety requirements and discuss several issues to consider when implementing thread-safety in MPI. We use the example of generating new context ids (required for creating new communicators) to demonstrate how a simple solution for the single-threaded case does not naturally extend to the multithreaded case and how a naove thread-safe algorithm can be expensive. We then present an algorithm for generating context ids that works efficiently in both single-threaded and multithreaded cases.

  16. [Safety assessment of nanomaterials using toxicokinetics and toxicoproteome analysis].

    PubMed

    Nabeshi, Hiromi; Yoshikawa, Tomoaki; Imazawa, Takayoshi; Tsunoda, Shin-Ichi; Tsutsumi, Yasuo

    2010-04-01

    With recent development of the nanotechnology, nanomaterials have been successfully employed in various industrial applications such as medicine and cosmetics. Nanomaterials show the useful properties such as electronic reactivity and the tissue permeability that were not provided by micromaterials. Thus, nanomaterials are expected as innovative materials for the development of medicine and cosmetics. However, these innovative properties may show unknown biological responses that could not been detected by the conventional toxicity assay. For industrial development and affluent society establishment that enjoyed only a benefit of nanomaterials, it is urgent to gather information of the properties and the biological effects, and to establish the standard safety evaluation method of nanomaterials. So, we are analyzing association among property, biodistribution and biological effects of nanomaterials to search for the safety biomarker (functional-, molecular- and biochemical-biomarker) using nanosilicas (nSP) as a standard nanomaterial. Because nSP shows high uniform dispersibility and is already used in medicine, cosmetics and food additive, the results of this study are useful to extrapolate it to other nanomaterials and to make practicable as safety biomarker. In this report, we show the latest knowledge about the linkage information among property, biodistribution and biological effects of nSP by toxicokinetics and toxicoproteomics, and the search study of safety biomarker based on these basic information. PMID:20371987

  17. A Radiation Safety Analysis for Lunar Lava Tubes

    NASA Technical Reports Server (NTRS)

    DeAngelis, G.; Wilson, J. W.; Clowdsley, M. S.; Nealy, J. E.; Humes, D. H.; Clem, J. M.

    2002-01-01

    The purpose of this work is an assessment of the lunar lava tubes physical characteristics and an evaluation of the their actual safety features from the point of view of the ionizing radiation environment as potential habitats for future lunar exploration crews. Additional information is contained in the original extended abstract.

  18. Predictors of Local Recurrence Following Accelerated Partial Breast Irradiation: A Pooled Analysis

    SciTech Connect

    Shah, Chirag; Wilkinson, John Ben [Department of Radiation Oncology, Beaumont Cancer Institute, Oakland University William Beaumont School of Medicine, Royal Oak, Michigan (United States); Lyden, Maureen [Biostat Inc., Tampa, Florida (United States); Beitsch, Peter [Dallas Breast Center, Dallas, Texas (United States); Vicini, Frank A., E-mail: fvicini@pol.net [Department of Radiation Oncology, Beaumont Cancer Institute, Oakland University William Beaumont School of Medicine, Royal Oak, Michigan (United States)

    2012-04-01

    Purpose: To analyze a pooled set of nearly 2,000 patients treated on the American Society of Breast Surgeons (ASBS) Mammosite Registry Trial and at William Beaumont Hospital (WBH) to identify factors associated with local recurrence following accelerated partial breast irradiation (APBI). Methods and Materials: A total of 1,961 women underwent partial breast irradiation between April 1993 and November 2010 as part of the ASBS Registry Trial or at WBH. Rates of ipsilateral breast tumor recurrence (IBTR), regional recurrence (RR), distant metastases (DM), disease-free survival (DFS), cause-specific survival (CSS), and overall survival (OS) were analyzed for each group and for the pooled cohort. Clinical, pathologic, and treatment-related variables were analyzed including age, tumor stage/size, estrogen receptor status, surgical margins, and lymph node status to determine their association with IBTR. Results: The two groups weres similar, but WBH patients were more frequently node positive, had positive margins, and were less likely to be within the American Society for Radiation Oncology-unsuitable group. At 5 years, the rates of IBTR, RR, DM, DFS, CSS, and OS for the pooled group of patients were 2.9%, 0.5%, 2.4%, 89.1%, 98.5%, and 91.8%, respectively. The 5-year rate of true recurrence/marginal miss was 0.8%. Univariate analysis of IBTR found that negative estrogen receptor status (odds ratio [OR], 2.83, 95% confidence interval 1.55-5.13, p = 0.0007) was the only factor significantly associated with IBTR, while a trend was seen for age less than 50 (OR 1.80, 95% confidence interval 0.90-3.58, p = 0.10). Conclusions: Excellent 5-year outcomes were seen following APBI in over 1,900 patients. Estrogen receptor negativity was the only factor associated with IBTR, while a trend for age less than 50 was noted. Significant differences in factors associated with IBTR were noted between cohorts, suggesting that factors driving IBTR may be predicated based on the risk stratification of the patients being treated.

  19. Interuser Interference Analysis for Direct-Sequence Spread-Spectrum Systems Part I: Partial-Period Cross-Correlation

    NASA Technical Reports Server (NTRS)

    Ni, Jianjun (David)

    2012-01-01

    This presentation discusses an analysis approach to evaluate the interuser interference for Direct-Sequence Spread-Spectrum (DSSS) Systems for Space Network (SN) Users. Part I of this analysis shows that the correlation property of pseudo noise (PN) sequences is the critical factor which determines the interuser interference performance of the DSSS system. For non-standard DSSS systems in which PN sequence s period is much larger than one data symbol duration, it is the partial-period cross-correlation that determines the system performance. This study reveals through an example that a well-designed PN sequence set (e.g. Gold Sequence, in which the cross-correlation for a whole-period is well controlled) may have non-controlled partial-period cross-correlation which could cause severe interuser interference for a DSSS system. Since the analytical derivation of performance metric (bit error rate or signal-to-noise ratio) based on partial-period cross-correlation is prohibitive, the performance degradation due to partial-period cross-correlation will be evaluated using simulation in Part II of this analysis in the future.

  20. Process hazards analysis (PrHA) program, bridging accident analyses and operational safety

    SciTech Connect

    Richardson, J. A. (Jeanne A.); McKernan, S. A. (Stuart A.); Vigil, M. J. (Michael J.)

    2003-01-01

    Recently the Final Safety Analysis Report (FSAR) for the Plutonium Facility at Los Alamos National Laboratory, Technical Area 55 (TA-55) was revised and submitted to the US. Department of Energy (DOE). As a part of this effort, over seventy Process Hazards Analyses (PrHAs) were written and/or revised over the six years prior to the FSAR revision. TA-55 is a research, development, and production nuclear facility that primarily supports US. defense and space programs. Nuclear fuels and material research; material recovery, refining and analyses; and the casting, machining and fabrication of plutonium components are some of the activities conducted at TA-35. These operations involve a wide variety of industrial, chemical and nuclear hazards. Operational personnel along with safety analysts work as a team to prepare the PrHA. PrHAs describe the process; identi fy the hazards; and analyze hazards including determining hazard scenarios, their likelihood, and consequences. In addition, the interaction of the process to facility systems, structures and operational specific protective features are part of the PrHA. This information is rolled-up to determine bounding accidents and mitigating systems and structures. Further detailed accident analysis is performed for the bounding accidents and included in the FSAR. The FSAR is part of the Documented Safety Analysis (DSA) that defines the safety envelope for all facility operations in order to protect the worker, the public, and the environment. The DSA is in compliance with the US. Code of Federal Regulations, 10 CFR 830, Nuclear Safety Management and is approved by DOE. The DSA sets forth the bounding conditions necessary for the safe operation for the facility and is essentially a 'license to operate.' Safely of day-to-day operations is based on Hazard Control Plans (HCPs). Hazards are initially identified in the PrI-IA for the specific operation and act as input to the HCP. Specific protective features important to worker safety are incorporated so the worker can readily identify the safety parameters of the their work. System safety tools such as Preliminary Hazard Analysis, What-If Analysis, Hazard and Operability Analysis as well as other techniques as necessary provide the groundwork for both determining bounding conditions for facility safety, operational safety, and day-to-clay worker safety.

  1. Analysis of Aviation Safety Reporting System Incident Data Associated with the Technical Challenges of the Atmospheric Environment Safety Technology Project

    NASA Technical Reports Server (NTRS)

    Withrow, Colleen A.; Reveley, Mary S.

    2014-01-01

    This study analyzed aircraft incidents in the NASA Aviation Safety Reporting System (ASRS) that apply to two of the three technical challenges (TCs) in NASA's Aviation Safety Program's Atmospheric Environment Safety Technology Project. The aircraft incidents are related to airframe icing and atmospheric hazards TCs. The study reviewed incidents that listed their primary problem as weather or environment-nonweather between 1994 and 2011 for aircraft defined by Federal Aviation Regulations (FAR) Parts 121, 135, and 91. The study investigated the phases of flight, a variety of anomalies, flight conditions, and incidents by FAR part, along with other categories. The first part of the analysis focused on airframe-icing-related incidents and found 275 incidents out of 3526 weather-related incidents over the 18-yr period. The second portion of the study focused on atmospheric hazards and found 4647 incidents over the same time period. Atmospheric hazards-related incidents included a range of conditions from clear air turbulence and wake vortex, to controlled flight toward terrain, ground encounters, and incursions.

  2. Combined genetic analysis of partial blast resistance in an upland rice population and recurrent selection for line and hybrid values.

    PubMed

    Veillet, S; Filippi, M C; Gallais, A

    1996-05-01

    The CNA-IRAT 5 upland rice population has been improved for 4 years by recurrent selection for blast resistance in Brazil. In order to predict the efficiency of recurrent selection in different test systems and to compare the relative advantage of hybrids versus pure line breeding, a combined genetic analysis of partial blast resistance in the CNA-IRAT 5 population was undertaken. A three-level hierarchical design in inbreeding and a factorial design were derived from the base population. Partial blast resistance of lines and hybrids was evaluated in the greenhouse and in the field by inoculation with one virulent blast isolate. The means and genetic variances of the hybrids and lines were estimated. Genetic advance by recurrent selection was predicted from estimates of variance components. The inheritance of partial blast resistance was mainly additive but non-additive effects were detected at both levels of means and variances. Mean heterosis ranged from 4%-8% for lesion size and lesion density to 10-12% for leaf and panicle resistance. High dominance or homozygous dominance variances relative to additive variance and negative covariance between additive and homozygous dominance effects were estimated. A low frequency of favourable alleles for partial resistance would explain the observed organisation of genetic variability in the base population. Recurrent selection will efficiently improve partial blast resistance of the CNA-IRAT 5 population. Genetic advance for line or hybrid values was expected to be higher testing doubled haploid lines than S1 lines, or than general combining ability. Two components of partial resistance assessed in the greenhouse, lesion size and lesion density, could be used as indirect selection criteria to improve field resistance. On the whole, hybrid breeding for partial blast resistance appeared to be slightly more advantageous than pure line breeding. PMID:24166386

  3. Model-Driven Safety Analysis of Closed-Loop Medical Systems

    PubMed Central

    Pajic, Miroslav; Mangharam, Rahul; Sokolsky, Oleg; Arney, David; Goldman, Julian; Lee, Insup

    2013-01-01

    In modern hospitals, patients are treated using a wide array of medical devices that are increasingly interacting with each other over the network, thus offering a perfect example of a cyber-physical system. We study the safety of a medical device system for the physiologic closed-loop control of drug infusion. The main contribution of the paper is the verification approach for the safety properties of closed-loop medical device systems. We demonstrate, using a case study, that the approach can be applied to a system of clinical importance. Our method combines simulation-based analysis of a detailed model of the system that contains continuous patient dynamics with model checking of a more abstract timed automata model. We show that the relationship between the two models preserves the crucial aspect of the timing behavior that ensures the conservativeness of the safety analysis. We also describe system design that can provide open-loop safety under network failure. PMID:24177176

  4. School food safety program based on hazard analysis and critical control point principles. Final rule.

    PubMed

    2009-12-15

    This final rule implements a legislative provision which requires school food authorities participating in the National School Lunch Program (NSLP) or the School Breakfast Program (SBP) to develop a school food safety program for the preparation and service of school meals served to children. The school food safety program must be based on the hazard analysis and critical control point (HACCP) system established by the Secretary of Agriculture. The food safety program will enable schools to take systematic action to prevent or minimize the risk of foodborne illness among children participating in the NSLP and SBP. PMID:20169679

  5. Analysis of developed transition road safety barrier systems.

    PubMed

    Soltani, Mehrtash; Moghaddam, Taher Baghaee; Karim, Mohamed Rehan; Sulong, N H Ramli

    2013-10-01

    Road safety barriers protect vehicles from roadside hazards by redirecting errant vehicles in a safe manner as well as providing high levels of safety during and after impact. This paper focused on transition safety barrier systems which were located at the point of attachment between a bridge and roadside barriers. The aim of this study was to provide an overview of the behavior of transition systems located at upstream bridge rail with different designs and performance levels. Design factors such as occupant risk and vehicle trajectory for different systems were collected and compared. To achieve this aim a comprehensive database was developed using previous studies. The comparison showed that Test 3-21, which is conducted by impacting a pickup truck with speed of 100 km/h and angle of 25° to transition system, was the most severe test. Occupant impact velocity and ridedown acceleration for heavy vehicles were lower than the amounts for passenger cars and pickup trucks, and in most cases higher occupant lateral impact ridedown acceleration was observed on vehicles subjected to higher levels of damage. The best transition system was selected to give optimum performance which reduced occupant risk factors using the similar crashes in accordance with Test 3-21. PMID:23820073

  6. Area-wide urban traffic calming schemes: a meta-analysis of safety effects

    Microsoft Academic Search

    Rune Elvik

    2001-01-01

    This paper presents a meta-analysis of 33 studies that have evaluated the effects on road safety of area-wide urban traffic calming schemes. Area-wide urban traffic calming schemes are typically implemented in residential areas in towns in order to reduce the environmental and safety problems caused by road traffic. A hierarchical road system is established and through traffic is removed from

  7. Bayesian Statistics and Uncertainty Quantification for Safety Boundary Analysis in Complex Systems

    NASA Technical Reports Server (NTRS)

    He, Yuning; Davies, Misty Dawn

    2014-01-01

    The analysis of a safety-critical system often requires detailed knowledge of safe regions and their highdimensional non-linear boundaries. We present a statistical approach to iteratively detect and characterize the boundaries, which are provided as parameterized shape candidates. Using methods from uncertainty quantification and active learning, we incrementally construct a statistical model from only few simulation runs and obtain statistically sound estimates of the shape parameters for safety boundaries.

  8. Review of Overall Safety Manual for space nuclear systems. An evaluation of a nuclear safety analysis methodology for plutonium-fueled space nuclear systems

    SciTech Connect

    Coleman, J.; Inhaber, H.

    1984-02-01

    As part of its duties in connection with space missions involving nuclear power sources, the Office of Nuclear Safety (ONS) of the Office of Assistant Secretary for Environmental Protection, Safety, and Emergency Preparedness has been assigned the task of reviewing the Overall Safety Manual (OSM) (memo from B.J. Rock to J.R. Maher, December 1, 1982). The OSM, dated July 1981 and in four volumes, was prepared by NUS Corporation, Rockville, Maryland, for the US Department of Energy. The OSM provides many of the technical models and much of the data which are used by (1) space launch contractors in safety analysis reports and (2) the broader Interagency Nuclear Safety Review Panel (INSRP) safety evaluation reports. If fhs interaction between the OSM, contractors, and INSRP is to work effectively, the OSM must be accurate, comprehensive, understandable, and usable.

  9. GEOGRAPHIC INFORMATION SYSTEMS-BASED CRASH DATA ANALYSIS AND THE BENEFITS TO TRAFFIC SAFETY

    Microsoft Academic Search

    Jerry Roche

    Geographic Information Systems (GIS) have been used in the past to display crash locations and produce maps. Today, the potential uses of GIS include crash data analysis. GIS-based crash data analysis can influence the four E's of traffic safety: engineering, enforcement, education, and emergency response. Macroscopic applications of GIS provide the ability to analyze a large amount of data quickly.

  10. A layered approach to automated electrical safety analysis in automotive environments

    Microsoft Academic Search

    C. J. Price; N. A. Snooke; S. D. Lewis

    2006-01-01

    Software support for the automotive electrical design process is vital, as many of the safety analysis tasks needing to be carried out, while complex, are repetitive and time consuming. Such support is required throughout the design process, but the available commercial tools are only appropriate at specific points in the design process—providing either an early rough analysis or a late

  11. MIT SDM Thesis Page 1 A System Theoretic Safety Analysis of U.S. Coast Guard

    E-print Network

    Leveson, Nancy

    Analysis Boards (MAB) in accordance with Coast Guard aviation policy. A MAB iJon Hickey MIT SDM Thesis Page 1 A System Theoretic Safety Analysis of U.S. Coast Guard Aviation and to distribute publicly paper and electronic copies of this thesis document in whole or in part in any medium now

  12. An Analysis of Trainers' Perspectives within an Ecological Framework: Factors that Influence Mine Safety Training Processes

    PubMed Central

    Haas, Emily J.; Hoebbel, Cassandra L.; Rost, Kristen A.

    2014-01-01

    Background Satisfactory completion of mine safety training is a prerequisite for being hired and for continued employment in the coal industry. Although training includes content to develop skills in a variety of mineworker competencies, research and recommendations continue to specify that specific limitations in the self-escape portion of training still exist and that mineworkers need to be better prepared to respond to emergencies that could occur in their mine. Ecological models are often used to inform the development of health promotion programs but have not been widely applied to occupational health and safety training programs. Methods Nine mine safety trainers participated in in-depth semi-structured interviews. A theoretical analysis of the interviews was completed via an ecological lens. Each level of the social ecological model was used to examine factors that could be addressed both during and after mine safety training. Results The analysis suggests that problems surrounding communication and collaboration, leadership development, and responsibility and accountability at different levels within the mining industry contribute to deficiencies in mineworkers' mastery and maintenance of skills. Conclusion This study offers a new technique to identify limitations in safety training systems and processes. The analysis suggests that training should be developed and disseminated with consideration of various levels—individual, interpersonal, organizational, and community—to promote skills. If factors identified within and between levels are addressed, it may be easier to sustain mineworker competencies that are established during safety training. PMID:25379324

  13. LESSONS LEARNED IN DEVELOPMENT OF THE HANFORD SWOC MASTER DOCUMENTED SAFETY ANALYSIS (MDSA) & IMPLEMENTATION VALIDATION REVIEW (IVR)

    SciTech Connect

    MORENO, M.R.

    2004-04-02

    DOE set clear expectations on a cost-effective approach for achieving compliance with the Nuclear Safety Management requirements (20 CFR 830, Nuclear Safety Rule), which ensured long-term benefit to Hanford, via issuance of a nuclear safety strategy in February 2003. To facilitate implementation of these expectations, tools were developed to streamline and standardize safety analysis and safety document development with the goal of a shorter and more predictable DOE approval cycle. A Hanford Safety Analysis and Risk Assessment Handbook (SARAH) was approved to standardize methodologies for development of safety analyses. A Microsoft Excel spreadsheet (RADIDOSE) was approved for the evaluation of radiological consequences for accident scenarios often postulated at Hanford. Standard safety management program chapters were approved for use as a means of compliance with the programmatic chapters of DOE-STD-3009, ''Preparation Guide for U.S. Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports''. An in-process review was developed between DOE and the Contractor to facilitate DOE approval and provide early course correction. The new Documented Safety Analysis (DSA) developed to address the operations of four facilities within the Solid Waste Operations Complex (SWOC) necessitated development of an Implementation Validation Review (IVR) process. The IVR process encompasses the following objectives: safety basis controls and requirements are adequately incorporated into appropriate facility documents and work instructions, facility personnel are knowledgeable of controls and requirements, and the DSA/TSR controls have been implemented. Based on DOE direction and safety analysis tools, four waste management nuclear facilities were integrated into one safety basis document. With successful completion of implementation of this safety document, lessons-learned from the in-process review, safety analysis tools and IVR process were documented for future action and consideration at other DOE sites.

  14. Scope on Safety: NSTA's portal into the safety zone

    NSDL National Science Digital Library

    Ken Roy

    2010-07-01

    NSTA's Science Safety Advisory Board recently launched the Safety in the Science Classroom portal, which contains safety resources for teachers, supervisors, and administrators. This month's column provides a partial listing of the resources middle schoo

  15. Stage Right operational safety analysis and evaluation of Pantex personnel operations

    SciTech Connect

    Rountree, S.L.K.; Whitehurst, H.O.; Tomlin, E.H.; Restrepo, L.F. [Sandia National Labs., Albuquerque, NM (United States); White, J. [Sandia National Labs., Albuquerque, NM (United States)]|[Intera, Albuquerque, NM (United States)

    1995-01-01

    This report documents a study (Stage Right Operational Safety Analysis) that was performed to evaluate the effects of new Stage Right operations on the safety of Pantex personnel who perform the operations and maintain the equipment. The primary concern of the evaluation was for personnel safety during Stage Right operations, but operations equipment damage and degradation also were taken into account. This analysis evaluates safety of the work process in the staging of dismantled nuclear weapon pits within the modified Richmond magazines only. This Stage Right Process and Operational Safety Analysis includes the following processes: moving the pelletized drums from the pallet trailer to the pallet turner, staging of pallets and removal of pallets from the magazine, recovery from an incident in a magazine, setting up, opening, and closing a Zone 4 magazine, inventory of pelletized drums in the magazines, transporting pelletized drums from Zone 12 to Zone 4, and maintenance on the shielded lift truck that involves removal of the cab shielding. The analysis includes the following undesirable consequences: injury to personnel, breach of an AL-R8 container, drop of a loaded pallet, damage to equipment, and equipment unreliability.

  16. 14 CFR 417.309 - Flight safety system analysis.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...margin, each link analysis must account for...and attenuation factors: (i) Path losses...margin, each link analysis must account for...and attenuation factors: (i) The system...other attenuation factors. (g) Sneak...a sneak circuit analysis. The...

  17. Analysis of Fundamental NIST Sphere Experiments Related to Criticality Safety

    SciTech Connect

    Kim, Soon S.

    2007-06-01

    A series of neutron transport experiments was performed in 1989 and 1990 at NIST (National Institute of Standards and Technology) using a spherical stainless steel container and fission chambers. These experiments were performed to help understand errors observed in criticality calculations for arrays of individually subcritical components, particularly solution arrays [1-3]. They were supported by the U.S. Department of Energy, Environment and Health, Nuclear Criticality Technology and Safety Project. The intent was to evaluate the possibility that the criticality prediction errors stem from errors in the calculation of neutron leakage from individual components of the array. Thus, the explicit product of the experiments was the measurement of the leakage flux, as characterized by various Cd-shielded and unshielded fission rates. Because the various fission rates have different neutron-energy sensitivities, collectively they give an indication of the energy dependence of the leakage flux. Leakage and moderation were varied systematically through the use of different diameter spheres, with and without water. Some of these experiments with bare fission chambers have been evaluated by the International Criticality Safety Benchmark Evaluation Project (ICSBEP)[4].

  18. Review and Analysis of Development of "Safety by Design" Requirements

    SciTech Connect

    Vance, Scott A.; Hockert, John

    2009-10-20

    This report, the deliverable for Task 4 of the NA-243 Safeguards by Design Work Plan for Fiscal Year 2009, develops the lessons to be learned for the institutionalization of Safeguards By Design (SBD) from the Department of Energy (DOE) experience developing and implementing DOE-STD-1189, Integration of Safety into the Design Process. This experience was selected for study because of the similarity of the challenges of integrating safety and safeguards into the design process. Development of DOE-STD-1189 began in January 2006 and the standard was issued for implementation in March 2008. The process was much more time consuming than originally anticipated and might not have come to fruition had senior DOE management been less committed to its success. Potentially valuable lessons can be learned from both the content and presentation of the integration approach in DOE-STD-1189 and from the DOE experience in developing and implementing DOE-STD-1189. These lessons are important because the instutionalization of SBD does not yet appear to have the level of senior management commitment afforded development and implementation of DOE-STD-1189.

  19. Performance Analysis of Matched and Partially Matched One-Shot Detectors for Doubly-Selective Rayleigh Fading Channels

    Microsoft Academic Search

    E. Chiavaccini; G. M. Vitetta

    2001-01-01

    In this paper optimum one-shot detection over known and partially known doubly-selective Rayleigh fading channels is investigated. Reduced complexity channel models based on Gauss Quadrature Rules (GQRs) and Taylor power series are derived and are employed to develop novel analytical tools for the performance analysis of one-shot detectors. Numerical results allow to assess the implicit diversity gain provided by both

  20. Mellin-Transform-Based Performance Analysis of FFH -ary FSK Using Product Combining for Combatting Partial-Band Noise Jamming

    Microsoft Academic Search

    Sohail Ahmed; Lie-Liang Yang; Lajos Hanzo

    2008-01-01

    We employ the Mellin transform to facilitate the bit error ratio (BER) analysis of a fast frequency hopping (FFH)-assisted, M-ary frequency-shift keying (MFSK) using product combining (PC) when the transmitted signal is subjected to both Rayleigh fading and partial-band noise jamming. Exploiting the fact that the Mellin transform of the product of independent random variables is the product of their

  1. Safety analysis report for the TRUPACT-II shipping package (condensed version). Volume 1, Rev. 14

    SciTech Connect

    NONE

    1994-10-01

    The condensed version of the TRUPACT-II Contact Handled Transuranic Waste Safety Analysis Report for Packaging (SARP) contains essential material required by TRUPACT-II users, plus additional contents (payload) information previously submitted to the U.S. Nuclear Regulatory Commission. All or part of the following sections, which are not required by users of the TRUPACT-II, are deleted from the condensed version: (i) structural analysis, (ii) thermal analysis, (iii) containment analysis, (iv) criticality analysis, (v) shielding analysis, and (vi) hypothetical accident test results.

  2. Applications of singular value analysis and partial-step algorithm for nonlinear orbit determination

    NASA Astrophysics Data System (ADS)

    Ryne, Mark S.; Wang, Tseng-Chan

    An adaptive method in which cruise and nonlinear orbit determination problems can be solved using a single program is presented. It involves singular value decomposition augmented with an extended partial step algorithm. The extended partial step algorithm constrains the size of the correction to the spacecraft state and other solve-for parameters. The correction is controlled by an a priori covariance and a user-supplied bounds parameter. The extended partial step method is an extension of the update portion of the singular value decomposition algorithm. It thus preserves the numerical stability of the singular value decomposition method, while extending the region over which it converges. In linear cases, this method reduces to the singular value decomposition algorithm with the full rank solution. Two examples are presented to illustrate the method's utility.

  3. PWR integrated safety analysis methodology using multi-level coupling algorithm

    NASA Astrophysics Data System (ADS)

    Ziabletsev, Dmitri Nickolaevich

    Coupled three-dimensional (3D) neutronics/thermal-hydraulic (T-H) system codes give a unique opportunity for a realistic modeling of the plant transients and design basis accidents (DBA) occurring in light water reactors (LWR). Examples of such DBAs are the rod ejection accidents (REA) and the main steam line break (MSLB) that constitute the bounding safety problems for pressurized water reactors (PWR). These accidents involve asymmetric 3D spatial neutronic and T-H effects during the course of the transients. The thermal margins (the peak fuel temperature, and departure from nucleate boiling ratio (DNBR)) are the measures of safety at a particular transient and need to be evaluated as accurate as possible. Modern 3D neutronics/T-H coupled codes estimate the safety margins coarsely on an assembly level, i.e. for an average fuel pin. More accurate prediction of the safety margins requires the evaluation of the transient fuel rod response involving locally coupled neutronics/T-H calculations. The proposed approach is to perform an on-line hot-channel safety analysis not for the whole core but for a selected local region, for example for the highest power loaded fuel assembly. This approach becomes feasible if an on-line algorithm capable to extract the necessary input data for a sub-channel module is available. The necessary input data include the detailed pin-power distributions and the T-H boundary conditions for each sub-channel in the considered problem. Therefore, two potential challenges are faced in the development of refined methodology for evaluation of local safety parameters. One is the development of an efficient transient pin-power reconstruction algorithm with a consistent cross-section modeling. The second is the development of a multi-level coupling algorithm for the T-H boundary and feed-back data exchange between the sub-channel module and the main 3D neutron kinetics/T-H system code, which already uses one level of coupling scheme between 3D neutronics and core thermal-hydraulics models. The major accomplishment of the thesis is the development of an integrated PWR safety analysis methodology with locally refined safety evaluations. This involved introduction of an improved method capable of efficiently restoring the fine pin-power distribution with a high degree of accuracy. In order to apply the methodology to evaluate the safety margins on a pin level, a refined on-line hot channel model was developed accounting for the cross-flow effects. Finally, this methodology was applied to best estimate safety analysis to more accurately calculate the thermal safety margins occurring during a design basis accident in PWR.

  4. System safety education focused on flight safety

    NASA Technical Reports Server (NTRS)

    Holt, E.

    1971-01-01

    The measures necessary for achieving higher levels of system safety are analyzed with an eye toward maintaining the combat capability of the Air Force. Several education courses were provided for personnel involved in safety management. Data include: (1) Flight Safety Officer Course, (2) Advanced Safety Program Management, (3) Fundamentals of System Safety, and (4) Quantitative Methods of Safety Analysis.

  5. The Frankfurt Patient Safety Climate Questionnaire for General Practices (FraSiK): analysis of psychometric properties.

    PubMed

    Hoffmann, Barbara; Domanska, Olga Maria; Albay, Zeycan; Mueller, Vera; Guethlin, Corina; Thomas, Eric J; Gerlach, Ferdinand M

    2011-09-01

    BACKGROUND Safety culture has been identified as having a major impact on how safety is managed in healthcare. However, it has not received much attention in general practices. Hence, no instrument yet exists to assess safety climate-the measurable artefact of safety culture-in this setting. This study aims to evaluate psychometric properties of a newly developed safety climate questionnaire for use in German general practices. METHODS The existing Safety Attitudes Questionnaire, Ambulatory Version, was considerably modified and enhanced in order to be applicable in general practice. After pilot tests and its application in a random sample of 400 German practices, a first psychometric analysis led to modifications in several items. A further psychometric analysis was conducted with an additional sample of 60 practices and a response rate of 97.08%. Exploratory factor analysis with orthogonal varimax rotation was carried out and the internal consistency of the identified factors was calculated. RESULTS Nine factors emerged, representing a wide range of dimensions associated with safety culture: teamwork climate, error management, safety of clinical processes, perception of causes of errors, job satisfaction, safety of office structure, receptiveness to healthcare assistants and patients, staff perception of management, and quality and safety of medical care. Internal consistency of factors is moderate to good. CONCLUSIONS This study demonstrates the development of a patient safety climate instrument. The questionnaire displays established features of safety climate and additionally contains features that might be specific to small-scale general practices. PMID:21571753

  6. Criticality safety analysis of Hanford Waste Tank 241-101-SY

    SciTech Connect

    Perry, R.T.; Sapir, J.L.; Krohn, B.J.

    1993-12-31

    As part of a safety assessment for proposed pump mixing operations to mitigate episodic gas releases in Tank 241-101-SY at the Hanford Site, Richland, Washington, a criticality safety analysis was made using the Sn transport code ONEDANT. The tank contains approximately one million gallons of waste and an estimated 910 G of plutonium. the criticality analysis considers reconfiguration and underestimation of plutonium content. The results indicate that Tank SY-101 does not present a criticality hazard. These methods are also used in criticality analyses of other Hanford tanks.

  7. Safety Analysis (SA) of the decontamination facility, Building 419, at the Lawrence Livermore National Laboratory

    SciTech Connect

    Odell, B.N.

    1980-06-17

    This safety analysis was performed for the Manager, Plant Services at LLNL and fulfills the requirements of DOE Order 5481.1. The analysis was based on field inspections, document review, computer calculations, and extensive input from Waste Management personnel. It was concluded that the maximum quantities of radioactive materials that safety procedures allow to be handled in this building do not pose undue risks on- or off-site even in postulated severe accidents. Risk from the various hazards at this facility vary from low to moderate as specified in DOE Order 5481.1. Recommendations are made for improvements that will reduce risks even further.

  8. Flood analysis using negative binomial and Generalized Pareto models in partial duration series (PDS)

    NASA Astrophysics Data System (ADS)

    Bhunya, P. K.; Berndtsson, R.; Jain, Sharad. K.; Kumar, Rakesh

    2013-08-01

    Two flood analysis estimation schemes, based on, respectively, partial duration series (PDS) and annual maximum series (AMS), are compared. The PDS model assumes a Generalized Pareto (GP) distribution for modeling the flood exceedances above threshold corresponding to a generalized extreme value (GEV) distribution for annual maxima. As a generalization of the common assumption of the Poisson distribution (PD) to count the occurrences of peaks over threshold in the PDS models, the advantage of negative binomial (NB) distribution is explored in this study. The T-year event estimator for the annual maximum distribution corresponding to the parent PDS model is formulated for producing AMS samples consistent with PDS samples which are used in simulations. The performance of the two models in terms of the uncertainty of the T-year event estimator is evaluated in the cases of estimation with the method of probability weighted moments (PWM). In a similar way, the performance of the derived PDS/NB-GP model is compared with the existing PDS/PD-GP model in terms of uncertainty of T-year event estimator using simulation and field data. The results show the T-year event estimate using PDS/NB-GP model yields lower variance compared to PDS/PD-GP models for most cases. However both the models perform similarly at higher return periods more than 300 years, using the ratios of the variance of T-years estimate as an index, and the ratio decreases with an increase in mean number of annual exceedances above threshold (?). From the results it is observed that both AMS and PDS models yield the same variance when ? varies from 1.4 to 1.65. However, in case of NB distribution the PDS and AMS models gives the same variance of q(T) when variance (?2) is 1.5 times the mean number of annual exceedance above threshold. The performance of the PDS models and the corresponding AMS models using the available data of Dee (at Cairnton) shows the PDS/NB-GP model to be marginally better at return periods lower than 50 years.

  9. Safety in the globalising knowledge economy: an analysis by paradoxes.

    PubMed

    Ravetz, J R

    2001-09-14

    There is a widespread recognition of a 'crisis' in official scientific expertise, related to the increase of 'uncertainty' and the loss of 'trust', and whose cure is believed to lie in 'participation'. I argue that the crisis results from structural features of the globalising knowledge economy, and the contradictory roles of governments, acting both as promoters of global business enterprise and also as regulators on behalf of a sophisticated and suspicious public. I explain the crisis by substituting 'safety' for 'risk' as the operative concept, and also using 'paradox' as an explanatory tool. I produce a closed-cycle paradox, analogous to the classic Catch-22, to exhibit the contradictions in the situation. I discuss ways of resolving these, which include the recognition of policy-critical ignorance and the adoption of the perspective of post-normal science. PMID:11532355

  10. A computer simulation analysis of the accuracy of partial genome sequencing and restriction fragment analysis in estimating genetic relationships: an application to papillomavirus DNA sequences

    Microsoft Academic Search

    Baozhen Qiao; Ronald M. Weigel

    2004-01-01

    Background: Determination of genetic relatedness among microorganisms provides information necessary for making inferences regarding phylogeny. However, there is little information available on how well the genetic relationships inferred from different genotyping methods agree with true genetic relationships. In this report, two genotyping methods - restriction fragment analysis (RFA) and partial genome DNA sequencing - were each compared to complete DNA

  11. A new algorithm for mixed Weibull analysis of partial discharge amplitude distributions

    Microsoft Academic Search

    R. Schifani; R. Candela

    1999-01-01

    In this paper, an heuristic algorithm is presented for the evaluation of the parameters of additive-Weibull distributions having more than two elementary functions, which is a necessary condition when testing complex insulating structures with different partial discharge (PD) sources. The algorithm has, in principle, no limit in the number of component Weibull functions. Furthermore, it should be emphasized that it

  12. COMPARISON AND ANALYSIS OF ON-LINE PARTIAL DISCHARGE MEASUREMENT METHODS FOR GAS INSULATION SUBSTATION

    Microsoft Academic Search

    Chien-Yi Chen; Cheng-Chi Tai; Ju-Chu Hsieh; Ching-Chau Su; Jiann-Fuh Chen

    In this paper, we compare and analyze the signals of acoustic emission (AE) sensor, high-frequency current transformer (HF-CT) and capacitive coupled (CC) sensor inspection methods when they are used to detect the partial discharge (PD) in gas isolation substations (GIS). The PD location feasibility of the AE method is also studied. In general, the leakage currents are measured by using

  13. Synteny analysis of loci controlling partial resistance to Aphanomyces euteiches between Pisum sativum and Medicago truncatula

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Aphanomyces root rot, due to Aphanomyces euteiches, is one of the most damaging diseases of pea worldwide. Breeding for partial polygenic resistance to Aphanomyces root rot is a major objective for the development of the pea crop in Europe. Our objectives were to study i)- the diversity of resistanc...

  14. Static, dynamic, and buckling analysis of partial interaction composite members using Timoshenko's beam theory

    Microsoft Academic Search

    Rongqiao Xu; Yufei Wu

    2007-01-01

    The static, dynamic, and buckling behavior of partial interaction composite members is investigated in this paper by taking into account for the influences of rotary inertia and shear deformations. The governing differential equations obtained are very comprehensive, covering and extending the current models for the problems that are based on Euler–Bernoulli beam theory. The analytical solutions of the deflection are

  15. Parent Ratings of ADHD Symptoms: Generalized Partial Credit Model Analysis of Differential Item Functioning across Gender

    ERIC Educational Resources Information Center

    Gomez, Rapson

    2012-01-01

    Objective: Generalized partial credit model, which is based on item response theory (IRT), was used to test differential item functioning (DIF) for the "Diagnostic and Statistical Manual of Mental Disorders" (4th ed.), inattention (IA), and hyperactivity/impulsivity (HI) symptoms across boys and girls. Method: To accomplish this, parents completed…

  16. Complex partial seizures of frontal lobe onset statistical analysis of ictal semiology

    Microsoft Academic Search

    P KOTAGAL; G ARUNKUMAR; J HAMMEL; ED MASCHA

    2003-01-01

    Objective: To identify the ictal semiology of complex partial seizures originating from the frontal lobe (FLCPS) and mesial temporal lobe (MTLE) in patients who became seizure free after surgery.Methods: We analysed 149 seizures from 42 patients, 28 with MTLE (75 seizures) and 14 with FLCPS (74 seizures) seizure free for at least 1 year after surgery. Fifty-eight symptoms and signs

  17. Survival analysis with long-term survivors and partially observed covariates

    Microsoft Academic Search

    Meehyung Cho; Nathaniel Schenker; Jeremy M. G. Taylor; Dongliang Zhuang

    2001-01-01

    The authors describe a method for tting failure time mixture models that postulate the existence of both susceptibles and long-term survivors when covariate data are only partially observed. Their method is based on a joint model that combines a Weibull regression model for the susceptibles, a logistic regression model for the probability of being a susceptible, and a general location

  18. Linking Socioeconomic Status to Social Cognitive Career Theory Factors: A Partial Least Squares Path Modeling Analysis

    ERIC Educational Resources Information Center

    Huang, Jie-Tsuen; Hsieh, Hui-Hsien

    2011-01-01

    The purpose of this study was to investigate the contributions of socioeconomic status (SES) in predicting social cognitive career theory (SCCT) factors. Data were collected from 738 college students in Taiwan. The results of the partial least squares (PLS) analyses indicated that SES significantly predicted career decision self-efficacy (CDSE);…

  19. Automating embedded analysis capabilities and managing software complexity in multiphysics simulation part II: application to partial differential equations

    E-print Network

    Pawlowski, Roger P; Salinger, Andrew G; Owen, Steven J; Siefert, Christopher M; Staten, Matthew L

    2012-01-01

    A template-based generic programming approach was presented in a previous paper that separates the development effort of programming a physical model from that of computing additional quantities, such as derivatives, needed for embedded analysis algorithms. In this paper, we describe the implementation details for using the template-based generic programming approach for simulation and analysis of partial differential equations (PDEs). We detail several of the hurdles that we have encountered, and some of the software infrastructure developed to overcome them. We end with a demonstration where we present shape optimization and uncertainty quantification results for a 3D PDE application.

  20. YUCCA MOUNTAIN SITE CHARACTERIZATIONS PROJECT TUNNEL BORING MACHINE (TBM) SYSTEM SAFETY ANALYSIS

    SciTech Connect

    N /A

    1997-02-19

    The purpose of this analysis is to systematically identify and evaluate hazards related to the tunnel boring machine (TBM) used in the Exploratory Studies Facility (ESF) at the Yucca Mountain Site Characterization Project. This process is an integral part of the systems engineering process; whereby safety is considered during planning, design, testing, and construction. Since the TBM is an ''as built'' system, the M&O is conducting the System Safety Analysis during the construction or assembly phase of the TBM. A largely qualitative approach was used since a radiological System Safety Analysis is not required. The risk assessment in this analysis characterizes the accident scenarios associated with the TBM in terms of relative risk and includes recommendations for mitigating all identified risks. The priority for recommending and implementing mitigation control features is: (1) Incorporate measures to reduce risks and hazards into the system/subsystem/component design, (2) add safety features and capabilities to existing designs, and (3) develop procedures and conduct training to increase worker awareness of potential hazards, on methods to reduce exposure to hazards, and on the actions required to avoid accidents or correct hazardous conditions. The scope of this analysis is limited to the TBM during normal operations, excluding hazards occurring during assembly and test of the TBM or maintenance of the TBM equipment.

  1. YUCCA MOUNTAIN SITE CHARACTERIZATION PROJECT EAST-WEST DRIFT SYSTEM SAFETY ANALYSIS

    SciTech Connect

    NA

    1999-06-08

    The purpose of this analysis is to systematically identify and evaluate hazards related to the design of the Yucca Mountain Project Exploratory Studies Facility (ESF) East-West Cross Drift. This analysis builds upon prior ESF System Safety Analyses and incorporates TS Main Drift scenarios, where applicable, into the East-West Drift scenarios. This System Safety Analysis (SSA) focuses on the personnel safety and health hazards associated with the engineered design of the East-West Drift. The analysis also evaluates other aspects of the East-West Drift, including purchased equipment (e.g., scientific mapping platform) or Systems/Structures/Components (SSCs) and out-of-tolerance conditions. In addition to recommending design mitigation features, the analysis identifies the potential need for procedures, training, or Job Safety Analyses (JSAs). The inclusion of this information in the SSA is intended to assist the organization(s) (e.g., constructor, Safety and Health, design) responsible for these aspects of the East-West Drift in evaluating personnel hazards and augment the information developed by these organizations. The SSA is an integral part of the systems engineering process, whereby safety is considered during planning, design, testing, and construction. A largely qualitative approach is used which incorporates operating experiences and recommendations from vendors, the constructor and the operating contractor. The risk assessment in this analysis characterizes the scenarios associated with East-West Drift SSCs in terms of relative risk and includes recommendations for mitigating all identified hazards. The priority for recommending and implementing mitigation control features is: (1) Incorporate measures to reduce risks and hazards into SSC designs. (2) Add safety features and capabilities to existing designs. (3) Develop procedures and conduct training to increase worker awareness of potential hazards, reduce exposure to hazards, and inform personnel of the actions required to avoid accidents or correct hazardous conditions. This analysis does not consider temporary construction items and, therefore, does not consider hazards associated with temporary construction items. This analysis will be reviewed and updated to reflect new East-West Drift design changes, construction modifications, and ''as built'' documentation of the East-West Drift when completed. A major difference between this analysis and previous ESF SSAs is the inclusion of hazards that arise as a result of non-accident events, (e.g., ''off-normal'' operations, adverse environmental conditions, or ''out-of-tolerance'' conditions). Non-accident events, that were not included in previous ESF SSAs, include environmental and/or toxic hazards such as leaking gases/fluids, off-gassing reactions, and excessive dust, particulates, exhaust fumes, noise, temperature, etc. which could have an adverse health effect on personnel.

  2. Costs and benefits of automotive fuel economy improvement: A partial analysis

    Microsoft Academic Search

    D. L. Greene; K. G. Duleep

    1992-01-01

    This paper is an exercise in estimating the costs and benefits of technology-based fuel economy improvements for automobiles and light trucks. Benefits quantified include vehicle cots, fuel savings, consumer's surplus effects, the effect of reduced weight on vehicle safety, impacts on emissions of COâ and criteria pollutants, world oil market and energy security benefits, and the transfer of wealth from

  3. Costs and benefits of automative fuel economy improvement: A partial analysis

    Microsoft Academic Search

    David L. Greene; K. G. Duleep

    1993-01-01

    This paper describes an exercise in estimating the costs and benefits of technology-based fuel economy improvements for automobiles and light trucks. Benefits quantified include vehicle costs, fuel savings, consumers' surplus effects, the effect of reduced weight on vehicle safety, impacts on emissions of CO2 and criteria pollutants, world oil market and energy security benefits, and the transfer of wealth from

  4. Costs and benefits of automotive fuel economy improvement: A partial analysis

    Microsoft Academic Search

    D. L. Greene; K. G. Duleep

    1992-01-01

    This paper is an exercise in estimating the costs and benefits of technology-based fuel economy improvements for automobiles and light trucks. Benefits quantified include vehicle cots, fuel savings, consumer`s surplus effects, the effect of reduced weight on vehicle safety, impacts on emissions of COâ and criteria pollutants, world oil market and energy security benefits, and the transfer of wealth from

  5. Skid Test for Department of Public Safety 

    E-print Network

    Unknown

    2011-08-17

    DEVELOPMENT OF A SAFETY ANALYSIS SYSTEM FOR THE OFFSHORE PERSONNEL AND EQUIPMENT TRANSFER PROCESS A Thesis by MICHAEL GEORGE McKENNA Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment... of the requirements for the degree of MASTER OF SCIENCE V Z December 1988 0 Z s Z LJ z X I Major Subject: Safety Engineering DEVELOPMENT OF A SAFETY ANALYSIS SYSTEM FOR THE OFFSHORE PERSONNEL AND EQUIPMENT TRANSFER PROCESS A Thesis by MICHAEL GEORGE Mc...

  6. Performance and Safety Analysis of a Generic Small Modular Reactor 

    E-print Network

    Kitcher, Evans Damenortey, 1987-

    2012-11-07

    of Coolant Accident LEU Low Enriched Uranium MAUA Multi Attribute Utility Analysis PWR Pressurized Water Reactor PR Proliferation Resistance SCA Single Channel Analysis SMR Small Modular Reactor vii TABLE OF CONTENTS Page... coolant for the reactor is light water which also acts as the moderator. The fuel is usually low enriched uranium (LEU) in the uranium dioxide (UO2) form, or occasionally mixed oxide containing both uranium dioxide and plutonium dioxide (UO2+PuO2...

  7. An advanced deterministic method for spent fuel criticality safety analysis

    SciTech Connect

    DeHart, M.D.

    1998-01-01

    Over the past two decades, criticality safety analysts have come to rely to a large extent on Monte Carlo methods for criticality calculations. Monte Carlo has become popular because of its capability to model complex, non-orthogonal configurations or fissile materials, typical of real world problems. Over the last few years, however, interest in determinist transport methods has been revived, due shortcomings in the stochastic nature of Monte Carlo approaches for certain types of analyses. Specifically, deterministic methods are superior to stochastic methods for calculations requiring accurate neutron density distributions or differential fluxes. Although Monte Carlo methods are well suited for eigenvalue calculations, they lack the localized detail necessary to assess uncertainties and sensitivities important in determining a range of applicability. Monte Carlo methods are also inefficient as a transport solution for multiple pin depletion methods. Discrete ordinates methods have long been recognized as one of the most rigorous and accurate approximations used to solve the transport equation. However, until recently, geometric constraints in finite differencing schemes have made discrete ordinates methods impractical for non-orthogonal configurations such as reactor fuel assemblies. The development of an extended step characteristic (ESC) technique removes the grid structure limitations of traditional discrete ordinates methods. The NEWT computer code, a discrete ordinates code built upon the ESC formalism, is being developed as part of the SCALE code system. This paper will demonstrate the power, versatility, and applicability of NEWT as a state-of-the-art solution for current computational needs.

  8. Linguistic analysis of large-scale medical incident reports for patient safety.

    PubMed

    Fujita, Katsuhide; Akiyama, Masanori; Park, Keunsik; Yamaguchi, Etsuko Nakagami; Furukawa, Hiroyuki

    2012-01-01

    The analysis of medical incident reports is indispensable for patient safety. The cycles between analysis of incident reports and proposals to medical staffs are a key point for improving the patient safety in the hospital. Most incident reports are composed from freely written descriptions, but an analysis of such free descriptions is not sufficient in the medical field. In this study, we aim to accumulate and reinterpret findings using structured incident information, to clarify improvements that should be made to solve the root cause of the accident, and to ensure safe medical treatment through such improvements. We employ natural language processing (NLP) and network analysis to identify effective categories of medical incident reports. Network analysis can find various relationships that are not only direct but also indirect. In addition, we compare bottom-up results obtained by NLP with existing categories based on experts' judgment. By the bottom-up analysis, the class of patient managements regarding patients' fallings and medicines in top-down analysis is created clearly. Finally, we present new perspectives on ways of improving patient safety. PMID:22874190

  9. Spent nuclear fuel project - criteria document spent nuclear fuel final safety analysis report

    SciTech Connect

    MORGAN, R.G.

    1999-02-23

    The criteria document provides the criteria and planning guidance for developing the Spent Nuclear Fuel (SNF) Final Safety Analysis Report (FSAR). This FSAR will support the US Department of Energy, Richland Operations Office decision to authorize the procurement, installation, installation acceptance testing, startup, and operation of the SNF Project facilities (K Basins, Cold Vacuum Drying Facility, and Canister Storage Building).

  10. The Range Safety Debris Catalog Analysis in Preparation for the Pad Abort One Flight Test

    NASA Technical Reports Server (NTRS)

    Kutty, Prasad; Pratt, William

    2010-01-01

    With each flight test a Range Safety Data Package is assembled to understand the potential consequences of various failure scenarios. Debris catalog analysis considers an overpressure failure of the Abort Motor and the resulting debris field created 1. Characterize debris fragments generated by failure: weight, shape, and area 2. Compute fragment ballistic coefficients 3. Compute fragment ejection velocities.

  11. ASSESSING NAVAL AVIATION MAINTENANCE SAFETY: Error Reporting, Data Management, and Trend Analysis

    Microsoft Academic Search

    John Schmidt; Dylan Schmorrow

    Naval Aviation has redoubled its long-standing efforts to eliminate mishaps, especially those linked to human error. The focus was expanded not only to cover aircrew error, but maintainer error as well. To examine maintainer error, the Naval Safety Center's Human Factors Analysis and Classification System (HFACS) was adapted to analyze reportable Naval Aviation maintenance mishaps. A total of 470 MRMs

  12. Finite element analysis of impact damage response of composite motorcycle safety helmets

    Microsoft Academic Search

    V Kostopoulos; Y. P Markopoulos; G Giannopoulos; D. E Vlachos

    2002-01-01

    The energy absorption during impact provided by a motorcycle safety helmet is always of critical importance in order to protect the rider against head injury during an accident. In the present study, a parametric analysis has been performed in order to investigate the effect of the composite shell stiffness and the damage development during impact, on the dynamic response of

  13. [Analysis of foreign experience of maintenance of biological safety of the Olympic Games].

    PubMed

    Onischenko, G G; Popova, A Yu; Smolensky, V Yu; Maletskaya, O V; Taran, T V; Dubyansky, V M; Semenko, O V; Agapitov, D S; Grizhebovsky, G M; Manin, E A; Klindukhov, V P; Oroby, V G; Antonenko, A D

    2015-01-01

    The analysis of the international experience in providing measures of health and disease safety at the Olympic Games was done. The stages of the formation of bio-security system at public events were considered, including measures to prevent infection outbreaks, the use of computer and information technologies. PMID:26016352

  14. Aircraft Autolander Safety Analysis Through Optimal Control-Based Reach Set Computation

    E-print Network

    Aircraft Autolander Safety Analysis Through Optimal Control-Based Reach Set Computation Alexandre M a maximal controlled invariant set and a set-valued control law guaranteed to keep the aircraft within on higher dimensional aircraft models. Nomenclature b = wingspan, m CL, CD = lift and drag coefficients D; V

  15. Safety Analysis of an Airbag System using Probabilistic FMEA and Probabilistic Counter Examples

    E-print Network

    Leue, Stefan

    Safety Analysis of an Airbag System using Probabilistic FMEA and Probabilistic Counter Examples to the FMEA process is illustrated by applying it to the case study of an airbag sys- tem provided by our using the real-life case study of an airbag system. We describe how to map the system architecture

  16. Aircraft Autolander Safety Analysis Through Optimal Control-Based Reach Set Computation

    Microsoft Academic Search

    Alexandre M. Bayen; Claire J. Tomlin; Meeko M. K. Oishi

    2007-01-01

    and safety analysis of autoland systems. It is shown to be applicable to specific phases of landing: descent, flare, and touchdown. The method is based on optimal control and level set methods; it simultaneously computes a maximal controlled invariant set and a set-valued control law guaranteed to keep the aircraft within a safe set of states under autopilot mode switching.

  17. Dynamic fault tree analysis using Monte Carlo simulation in probabilistic safety assessment

    Microsoft Academic Search

    K. Durga Rao; V. Gopika; V. V. S. Sanyasi Rao; H. S. Kushwaha; A. K. Verma; A. Srividya

    2009-01-01

    Traditional fault tree (FT) analysis is widely used for reliability and safety assessment of complex and critical engineering systems. The behavior of components of complex systems and their interactions such as sequence- and functional-dependent failures, spares and dynamic redundancy management, and priority of failure events cannot be adequately captured by traditional FTs. Dynamic fault tree (DFT) extend traditional FT by

  18. Degradable Agreement with Hybrid Faults (An Algorithm and Reliability-Safety Analysis)

    E-print Network

    Vaidya, Nitin

    Degradable Agreement with Hybrid Faults (An Algorithm and Reliability-Safety Analysis) Nitin H Byzantine agreement in the presence of arbitrary faults re- quires that the total number of nodes be larger to circumvent this re- quirement: (i) hybrid fault model approach 4, 7] considers three types of faults

  19. Criticality evaluation for the ATMX-600 rail car safety analysis report

    Microsoft Academic Search

    Paynter

    1986-01-01

    The ATMX-600 rail car is used by Rockwell International, Rocky Flats Plant, for shipping transuranic radioactive waste under provisions of US Department of Transportation (DOT) exemption E-5948. Recently, the safety analysis report for this container was revised to reflect minor operational changes and to propose new fissile material limits for the inner containers so as to increase the efficiency of

  20. NSAC: in-depth look at Three Mile Island. [Nuclear Safety Analysis Center, EPRI headquarters

    Microsoft Academic Search

    N. Lihach; E. Zebroski

    1979-01-01

    The Nuclear Safety Analysis Center (NSAC) is hoping to learn what caused the reactor accident at Three Mile Island, what happened during the accident, and how to take advantage of what is learned to prevent future incidents. When the Electric Power Research Institute (EPRI) was asked to make an independent assessment, the NSAC was organized with a separate identity and

  1. High-Level Waste Preclosure Systems Safety Analysis. Phase 1. Final report

    Microsoft Academic Search

    P. A. Harris; D. M. Ligon; M. G. Stamatelatos

    1985-01-01

    The major effort for this phase of the project has been on the gathering, organizing, and assembling of information pertinent to the safety assessment of a nuclear waste repository during preclosure operations. Specific issues addressed in this report are: (1) detailed analysis of a conceptual basalt repository design in order to identify potential initiating events\\/accident scenarios capable of causing radiological

  2. Safety and Response-Time Analysis of an Automotive Accident Assistance Service

    E-print Network

    Gilmore, Stephen

    Safety and Response-Time Analysis of an Automotive Accident Assistance Service Ashok Argent of the service which they provide in terms of both its correctness of function and its speed of response. One way the on-board diagnostic and communication systems in high-end cars to provide an accident assistance

  3. Safety analysis of first 1000 patients treated with magnetic sphincter augmentation for gastroesophageal reflux disease.

    PubMed

    Lipham, J C; Taiganides, P A; Louie, B E; Ganz, R A; DeMeester, T R

    2015-05-01

    Antireflux surgery with a magnetic sphincter augmentation device (MSAD) restores the competency of the lower esophageal sphincter with a device rather than a tissue fundoplication. As a regulated device, safety information from the published clinical literature can be supplemented by tracking under the Safe Medical Devices Act. The aim of this study was to examine the safety profile of the MSAD in the first 1000 implanted patients. We compiled safety data from all available sources as of July 1, 2013. The analysis included intra/perioperative complications, hospital readmissions, procedure-related interventions, reoperations, and device malfunctions leading to injury or inability to complete the procedure. Over 1000 patients worldwide have been implanted with the MSAD at 82 institutions with median implant duration of 274 days. Event rates were 0.1% intra/perioperative complications, 1.3% hospital readmissions, 5.6% endoscopic dilations, and 3.4% reoperations. All reoperations were performed non-emergently for device removal, with no complications or conversion to laparotomy. The primary reason for device removal was dysphagia. No device migrations or malfunctions were reported. Erosion of the device occurred in one patient (0.1%). The safety analysis of the first 1000 patients treated with MSAD for gastroesophageal reflux disease confirms the safety of this device and the implantation technique. The overall event rates were low based on data from 82 institutions. The MSAD is a safe therapeutic option for patients with chronic, uncomplicated gastroesophageal reflux disease. PMID:24612509

  4. Phase-Change Characteristic Analysis of Partially Melted Sodium Acetate Trihydrate Using DSC

    NASA Astrophysics Data System (ADS)

    Jin, Xing; Medina, Mario A.; Zhang, Xiaosong; Zhang, Shuanglong

    2014-01-01

    Sodium acetate trihydrate (SAT), which is a kind of phase-change material, offers high potential for application in thermal energy storage. However, SAT has a natural tendency to supercool during its solidification process. Adding nucleating agents has been suggested as a possible solution. In this paper, the phase-change characteristics of the partially melted SAT were analyzed using a differential scanning calorimeter (DSC). A phenomenon related to SAT undergoing phase change was discovered and analyzed. The results showed that if SAT were cooled when it was partially melted, it would release heat and quickly solidify without adding any nucleating agents. Therefore, if the temperature range of SAT was controlled properly, supercooling could be significantly prevented.

  5. Measurements and analysis of surface damage on oil-impregnated insulation paper caused by partial discharge

    NASA Astrophysics Data System (ADS)

    Yan, Jiaming; Liao, Ruijin; Yang, Lijun; Zhu, Mengzhao

    2011-05-01

    Surface topography, surface roughness, and surface conductivity of oil-impregnated insulation paper were studied during the damage process caused by partial discharge within the cavity of the paper. Products generated on the surface during this process were studied, as well. According to phase-resolved partial discharge patterns, the damage process can be divided into five stages. At each of the stages, surface conditions of insulation were analyzed by optical microscopy, scanning electron microscopy, atomic force microscopy and high-resistance meter. 'Ablating', 'peeling', 'cracking in silk', 'pitting' and 'electrical treeing' appear on insulation surfaces one after another during the five stages of the damage process, along with sequential generation of droplets and crystalline solids. Surface roughness initially decreases, then increases. Finally, surface conductivity exhibits a general increasing trend, before it eventually stabilizes. However, its growth rate varies in different stages of damage.

  6. Analysis of load transfer and stress distribution by an implant-supported fixed partial denture

    Microsoft Academic Search

    David Assif; Barry Marshak; Amir Horowitz

    1996-01-01

    This study simultaneously examined the load transfer and stress distribution by an implant-supported fixed partial denture. A mandibular implant framework with implants connected to the abutments was embedded in a three-dimensional photoelastic model of a mandible. Strain gauges were attached on the superior surface of the framework, and a vertical load of 7.5 kg was applied to seven points on

  7. SYSTEMS SAFETY ANALYSIS FOR FIRE EVENTS ASSOCIATED WITH THE ECRB CROSS DRIFT

    SciTech Connect

    R. J. Garrett

    2001-12-12

    The purpose of this analysis is to systematically identify and evaluate fire hazards related to the Yucca Mountain Site Characterization Project (YMP) Enhanced Characterization of the Repository Block (ECRB) East-West Cross Drift (commonly referred to as the ECRB Cross-Drift). This analysis builds upon prior Exploratory Studies Facility (ESF) System Safety Analyses and incorporates Topopah Springs (TS) Main Drift fire scenarios and ECRB Cross-Drift fire scenarios. Accident scenarios involving the fires in the Main Drift and the ECRB Cross-Drift were previously evaluated in ''Topopah Springs Main Drift System Safety Analysis'' (CRWMS M&O 1995) and the ''Yucca Mountain Site Characterization Project East-West Drift System Safety Analysis'' (CRWMS M&O 1998). In addition to listing required mitigation/control features, this analysis identifies the potential need for procedures and training as part of defense-in-depth mitigation/control features. The inclusion of this information in the System Safety Analysis (SSA) is intended to assist the organization(s) (e.g., Construction, Environmental Safety and Health, Design) responsible for these aspects of the ECRB Cross-Drift in developing mitigation/control features for fire events, including Emergency Refuge Station(s). This SSA was prepared, in part, in response to Condition/Issue Identification and Reporting/Resolution System (CIRS) item 1966. The SSA is an integral part of the systems engineering process, whereby safety is considered during planning, design, testing, and construction. A largely qualitative approach is used which incorporates operating experiences and recommendations from vendors, the constructor and the operating contractor. The risk assessment in this analysis characterizes the scenarios associated with fires in terms of relative risk and includes recommendations for mitigating all identified hazards. The priority for recommending and implementing mitigation control features is: (1) Incorporate measures to reduce risks and hazards into Structure, System, or Component (SSC) designs; (2) Add safety features and capabilities to existing designs; and (3) Develop procedures and conduct training to increase worker awareness of potential hazards, reduce exposure to hazards, and inform personnel of the actions required to avoid accidents or correct hazardous conditions.

  8. Comprehensive safety analysis code system for nuclear fusion reactors II: Thermal analysis during plasma disruptions for international thermonuclear experimental reactor

    Microsoft Academic Search

    T. Honda; K. Maki; T. Okazaki

    1994-01-01

    Thermal characteristics of a fusion reactor [International Thermonuclear Experimental Reactor (ITER) Conceptual Design Activity] during plasma disruptions have been analyzed by using a comprehensive safety analysis code for nuclear fusion reactors. The erosion depth due to disruptions for the armor of the first wall depends on the current quench time of disruptions occurring in normal operation. If it is possible

  9. Safety analysis, 200 Area, Savannah River Plant H-Canyon operations. Supplement 5

    Microsoft Academic Search

    M. M. Beary; C. D. Collier; L. A. Fairobent; R. F. Graham; C. L. Mason; W. T. McDuffee; T. L. Owen; D. H. Walker

    1986-01-01

    The H-Canyon facility is located in the 200 Separations Area and uses the HM process to separate uranium, neptunium, plutonium, and fission products. Irradiated uranium fuels containing ²³⁵U at enrichments from 1.1% to 94% are processed and recovered, along with neptunium and plutonium isotopes. This Safety Analysis Report (SAR) documents an analysis of the H-Canyon operations and is an update

  10. Safety analysis, 200 Area, Savannah River Plant H-Canyon operations

    Microsoft Academic Search

    M. M. Beary; C. D. Collier; L. A. Fairobent; R. F. Graham; C. L. Mason; W. T. McDuffee; T. L. Owen; D. H. Walker

    1986-01-01

    The H-Canyon facility is located in the 200 Separations Area and uses the HM process to separate uranium, neptunium, plutonium, and fission products. Irradiated uranium fuels containing [sup 235]U at enrichments from 1.1% to 94% are processed and recovered, along with neptunium and plutonium isotopes. This Safety Analysis Report (SAR) documents an analysis of the H-Canyon operations and is an

  11. Mining Safety Signals in Spontaneous Reports Database Using Concept Analysis

    Microsoft Academic Search

    Mohamed Rouane Hacene; Yannick Toussaint; Petko Valtchev

    2009-01-01

    In pharmacovigilance, linking the adverse reactions by pa- tients to drugs they took is a key activity typically based on the analysis of patient reports. Yet generating potentially interesting pairs (drug, re- action) from a record database is a complex task, especially when many drugs are involved. To limit the generation eort, we exploit the fre- quently occurring patterns in

  12. Advances in coupled safety modeling using systems analysis and high-fidelity methods.

    SciTech Connect

    Fanning, T. H.; Thomas, J. W.; Nuclear Engineering Division

    2010-05-31

    The potential for a sodium-cooled fast reactor to survive severe accident initiators with no damage has been demonstrated through whole-plant testing in EBR-II and FFTF. Analysis of the observed natural protective mechanisms suggests that they would be characteristic of a broad range of sodium-cooled fast reactors utilizing metal fuel. However, in order to demonstrate the degree to which new, advanced sodium-cooled fast reactor designs will possess these desired safety features, accurate, high-fidelity, whole-plant dynamics safety simulations will be required. One of the objectives of the advanced safety-modeling component of the Reactor IPSC is to develop a science-based advanced safety simulation capability by utilizing existing safety simulation tools coupled with emerging high-fidelity modeling capabilities in a multi-resolution approach. As part of this integration, an existing whole-plant systems analysis code has been coupled with a high-fidelity computational fluid dynamics code to assess the impact of high-fidelity simulations on safety-related performance. With the coupled capabilities, it is possible to identify critical safety-related phenomenon in advanced reactor designs that cannot be resolved with existing tools. In this report, the impact of coupling is demonstrated by evaluating the conditions of outlet plenum thermal stratification during a protected loss of flow transient. Outlet plenum stratification was anticipated to alter core temperatures and flows predicted during natural circulation conditions. This effect was observed during the simulations. What was not anticipated, however, is the far-reaching impact that resolving thermal stratification has on the whole plant. The high temperatures predicted at the IHX inlet due to thermal stratification in the outlet plenum forces heat into the intermediate system to the point that it eventually becomes a source of heat for the primary system. The results also suggest that flow stagnation in the intermediate system is possible, raising questions about the effectiveness of the intermediate decay heat removal systems in the design that was evaluated. Existing tools do not predict flow stagnation. This work has demonstrated that with a proper coupling approach, a high-fidelity CFD tool can be used to resolve the important flow and temperature distributions throughout a plant while still maintaining the whole-plant safety analysis capabilities of a systems analysis code.

  13. Safety analysis report: evaluation of passive re-entry approach

    Microsoft Academic Search

    J. M. Bridges; W. S. Brown; D. W. Call; J. D. Cleary; H. G. Hargrove; M. R. Trammell

    1965-01-01

    An analysis is made to predict the behavior of a nuclear rocket engine ;\\u000a in the event of an in-flight failure subsequent to stantup of the nuclear stage. ;\\u000a The accident model assumes loss-of-coolant to the reactor at time of system ;\\u000a failure. It is also assumed that the only direct action taken subsequent to ;\\u000a failure is separation of

  14. FINAL SAFETY ANALYSIS REPORT. SNAP III THERMOELECTRIC GENERATOR

    Microsoft Academic Search

    W. Hagis; G. P. Dix

    1960-01-01

    The SNAP-III thermoelectric generator procedures power from the decay ;\\u000a heat of 2100 curies of Po²¹°. This generator is to be used as a source of ;\\u000a auxiliary power in a terrestrial satellite. For purposes of analysis, the ;\\u000a satellite system postulated is launched from the Pacific Missile Bange into a 275-;\\u000a statute mile polar orbit with an orbital lifetime

  15. Quantitative infrared spectroscopic analysis of SF 6 decomposition products obtained by electrical partial discharges and sparks using PLS-calibrations

    NASA Astrophysics Data System (ADS)

    Kurte, R.; Heise, H. M.; Klockow, D.

    2001-05-01

    Infrared spectroscopy is a powerful tool for the analysis of gaseous by-products in sulfur hexafluoride gas used as an insulator in high-voltage equipment. Sparks and electrical partial discharges were generated between different point-plane configurations within a custom-made discharge chamber constructed from stainless steel and Teflon ®. Various electrode materials were used such as stainless steel, copper, aluminium, silver, tungsten and tungsten/copper alloy. Owing to the different electrical conditions, a wide concentration range of the decomposition products existed. The main-products found were the sulfuroxyfluorides SOF 4 and SOF 2, as well as HF following experiments with partial discharges and sparking with energies around 1.0 J/spark. All infrared spectra were recorded using an FTIR-spectrometer equipped with a 10 cm gas cell. Quantification was carried out using classical least-squares and partial least-squares (PLS) with multivariate spectral data from selected intervals. PLS calibration models were also optimised under the constraint of a minimum number of spectral variables with a view to developing simple photometers based on a restricted number of laser wavelengths. Standard errors of prediction obtained by cross-validation of different PLS calibration models are reported for the compounds mentioned, as well as for SF 4, SO 2F 2 and SiF 4.

  16. [Partial least-squares regression analysis for simultaneous spectrophotometric determination of Fe3+ and Al3+].

    PubMed

    Peng, Shu-chuan; Huang, Chuan-hui; Chen, Tian-hu; Jiang, Shao-tong; Feng, You-liang

    2005-06-01

    Adding hexodecyltrimethylammonium bromide(CTMAB) to improve solubility and delicacy, and using chromazurol S as a chromogenic reagent, and acetone as a stabilizing reagent, partial least-squares regression(PLS) was used to determine simultaneously trace amounts of Fe(III) and Al(III) in sythetic samples. Considering the stability of the rays, and the absorption properties of the two ingredients, seven wavelengths between 610 and 670 nm were selected for data collection. As a comparison, the methods of CPA and PLS were used respectively for analysing the data obtained from the experiment, and the results suggested that the latter was much better. PMID:16201378

  17. Receiving Basin for Offsite Fuels and the Resin Regeneration Facility Safety Analysis Report, Executive Summary

    SciTech Connect

    Shedrow, C.B.

    1999-11-29

    The Safety Analysis Report documents the safety authorization basis for the Receiving Basin for Offsite Fuels (RBOF) and the Resin Regeneration Facility (RRF) at the Savannah River Site (SRS). The present mission of the RBOF and RRF is to continue in providing a facility for the safe receipt, storage, handling, and shipping of spent nuclear fuel assemblies from power and research reactors in the United States, fuel from SRS and other Department of Energy (DOE) reactors, and foreign research reactors fuel, in support of the nonproliferation policy. The RBOF and RRF provide the capability to handle, separate, and transfer wastes generated from nuclear fuel element storage. The DOE and Westinghouse Savannah River Company, the prime operating contractor, are committed to managing these activities in such a manner that the health and safety of the offsite general public, the site worker, the facility worker, and the environment are protected.

  18. On the partial-wave analysis of mesonic resonances decaying to multiparticle final states produced by polarized photons

    NASA Astrophysics Data System (ADS)

    Salgado, Carlos W.; Weygand, Dennis P.

    2014-04-01

    Meson spectroscopy is going through a revival with the advent of high statistics experiments and new advances in the theoretical predictions. The Constituent Quark Model (CQM) is finally being expanded considering more basic principles of field theory and using discrete calculations of Quantum Chromodynamics (lattice QCD). These new calculations are approaching predictive power for the spectrum of hadronic resonances and decay modes. It will be the task of the new experiments to extract the meson spectrum from the data and compare with those predictions. The goal of this report is to describe one particular technique for extracting resonance information from multiparticle final states. The technique described here, partial wave analysis based on the helicity formalism, has been used at Brookhaven National Laboratory (BNL) using pion beams, and Jefferson Laboratory (JLab) using photon beams. In particular this report broadens this technique to include production experiments using linearly polarized real photons or quasi-real photons. This article is of a didactical nature. We describe the process of analysis, detailing assumptions and formalisms, and is directed towards people interested in starting partial wave analysis.

  19. On the Partial-Wave Analysis of Mesonic Resonances Decaying to Multiparticle Final States Produced by Polarized Photons

    SciTech Connect

    Salgado, Carlos W. [Norfolk State University, Norfolk, VA (United States) and Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Weygand, Dennis P. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States)

    2014-04-01

    Meson spectroscopy is going through a revival with the advent of high statistics experiments and new advances in the theoretical predictions. The Constituent Quark Model (CQM) is finally being expanded considering more basic principles of field theory and using discrete calculations of Quantum Chromodynamics (lattice QCD). These new calculations are approaching predictive power for the spectrum of hadronic resonances and decay modes. It will be the task of the new experiments to extract the meson spectrum from the data and compare with those predictions. The goal of this report is to describe one particular technique for extracting resonance information from multiparticle final states. The technique described here, partial wave analysis based on the helicity formalism, has been used at Brookhaven National Laboratory (BNL) using pion beams, and Jefferson Laboratory (Jlab) using photon beams. In particular this report broaden this technique to include production experiments using linearly polarized real photons or quasi-real photons. This article is of a didactical nature. We describe the process of analysis, detailing assumptions and formalisms, and is directed towards people interested in starting partial wave analysis.

  20. Partial least-squares-discriminant analysis differentiating Chinese wolfberries by UPLC-MS and flow injection mass spectrometric (FIMS) fingerprints.

    PubMed

    Lu, Weiying; Jiang, Qianqian; Shi, Haiming; Niu, Yuge; Gao, Boyan; Yu, Liangli Lucy

    2014-09-17

    Lycium barbarum L. fruits (Chinese wolfberries) were differentiated for their cultivation locations and the cultivars by ultraperformance liquid chromatography coupled with mass spectrometry (UPLC-MS) and flow injection mass spectrometric (FIMS) fingerprinting techniques combined with chemometrics analyses. The partial least-squares-discriminant analysis (PLS-DA) was applied to the data projection and supervised learning with validation. The samples formed clusters in the projected data. The prediction accuracies by PLS-DA with bootstrapped Latin partition validation were greater than 90% for all models. The chemical profiles of Chinese wolfberries were also obtained. The differentiation techniques might be utilized for Chinese wolfberry authentication. PMID:25152955

  1. Is it possible to anticipate seizure onset by non-linear analysis of intracerebral EEG in human partial epilepsies?

    PubMed

    Lehnertz, K; Widman, G; Andrzejak, R; Arnhold, J; Elger, C E

    1999-07-01

    Detection of electrophysiological features preceding and indicative of imminent seizures in patients with epilepsy would be a major breakthrough with immense scientific and clinical implications. The definition of a "pre-ictal state" several minutes prior to seizure onset would open a new time window for studying mechanisms of seizure generation as well as for possible therapeutic interventions. In this review we present recent findings from nonlinear time series analysis of intracranially recorded EEG that may allow to forecast seizure onset in patients with partial epilepsy. PMID:10472658

  2. Developing a Comprehensive Software Suite for Advanced Reactor Performance and Safety Analysis

    SciTech Connect

    Pointer, William David [ORNL] [ORNL; Bradley, Keith S [ORNL] [ORNL; Fischer, Paul F [ORNL] [ORNL; Smith, Micheal A [ORNL] [ORNL; Tautges, Timothy J [ORNL] [ORNL; Ferencz, Robert M [ORNL] [ORNL; Martineau, Richard C [ORNL] [ORNL; Jain, Rajeev [ORNL] [ORNL; Obabko, Aleksandr [Argonne National Laboratory (ANL)] [Argonne National Laboratory (ANL); Billings, Jay Jay [ORNL] [ORNL

    2013-01-01

    This paper provides an introduction to the reactor analysis capabilities of the nuclear power reactor simulation tools that are being developed as part of the U.S. Department of Energy s Nuclear Energy Advanced Modeling and Simulation (NEAMS) Toolkit. The NEAMS Toolkit is an integrated suite of multi-physics simulation tools that leverage high-performance computing to reduce uncertainty in the prediction of performance and safety of advanced reactor and fuel designs. The Toolkit effort is comprised of two major components, the Fuels Product Line (FPL), which provides tools for fuel performance analysis, and the Reactor Product Line (RPL), which provides tools for reactor performance and safety analysis. This paper provides an overview of the NEAMS RPL development effort.

  3. Static Analysis Tools, a Practical Approach for Safety-Critical Software Verification

    NASA Astrophysics Data System (ADS)

    Lopes, R.; Vicente, D.; Silva, N.

    2009-05-01

    Static code analysis tools available today range from Lintbased syntax parsers to standards' compliance checkers to tools using more formal methods for verification. As safety critical software complexity is increasing, these tools provide a mean to ensure code quality, safety and dependability attributes. They also provide a mean to introduce further automation in code analysis activities. The features presented by static code analysis tools are particularly interesting for V&V activities. In the scope of Independent Code Verification (IVE), two different static analysis tools have been used during Code Verification activities of the LISA Pathfinder onboard software in order to assess their contribution to the efficiency of the process and quality of the results. Polyspace (The MathWorks) and FlexeLint (Gimpel) tools have been used as examples of high-budget and low-budget tools respectively. Several aspects have been addressed: effort has been categorised for closer analysis (e.g. setup and configuration time, execution time, analysis of the results, etc), reported issues have been categorised according to their type and the coverage of traditional IVE tasks by the static code analysis tools has been evaluated. Final observations have been performed by analysing the previously referred subjects, namely regarding cost effectiveness, quality of results, complementarities between the results of different static code analysis tools and relation between automated code analysis and manual code inspection.

  4. Improvement of three-field based safety analysis code, SPACE, through verification and validation

    SciTech Connect

    Yang, J. H.; Kim, J. H.; Park, G. C. [Nuclear Thermal-Hydraulic Engineering Laboratory, Seoul National Univ., Gwanak-599 Gwanak-ro, Gwanak-gu, Seoul 151-742 (Korea, Republic of)

    2012-07-01

    To verify and validate the state-of-the-art safety analysis code, SPACE, features of three field governing equations were arranged and the comparative analysis with both analytic solution and experimental benchmarks were performed. With the world wide streamline on the safety analysis, SPACE uses two-fluid, three-field governing equations which aim to implement multi-dimensional and multi-scaled analysis. Through the Verification and Validation (V and V), developing code based on the three-field governing equation have not only been confirmed but also improved. V and V activities on SPACE have been conducted as to interfacial drag model in vertical turbulent flow. The verification of the interfacial drag model was based on cell size sensitivity test for confirming feasible calculation range of cell size. Furthermore, through the validation with analytic solution, the modification of the interfacial drag model in vertical turbulent annulus flow was carried out and the nominated model was incorporated. Modified interfacial drag model, Asali's correlation, yields improved result than previous interfacial drag model. The validation with experimental benchmarks had also been performed on the nearly horizontal counter current limitation. To confirm the possibility of the further application of the CCFL model in case with horizontal pipe, validation with nearly horizontal pipe experiment was carried out. V and V activities of SPACE with analytic solution and experimental benchmarks allow us to confirm/identify the tailorability for safety analysis. (authors)

  5. Yucca Mountain Site Charecterization Project Design Package 1C System Safety Analysis

    SciTech Connect

    TRW

    1995-10-16

    The purpose of this analysis is to systematically identify and evaluate hazards related to the Yucca Mountain Project Exploratory Studies Facility (ESF) Design Package IC, Surface Utilities (for a list of package 1C subsystems see section 3). This process is an integral part of the systems engineering process; whereby safety is considered during planning, design, testing, and construction. A largely qualitative approach was used since a radiological System Safety Analysis is not required. The risk assessment in this analysis characterizes the accident scenarios associated with the Design Package 1C structures/systems/components in terms of relative risk and includes recommendations for mitigating all identified risks. The priority for recommending and implementing mitigation control features is: (1) Incorporate measures to reduce risks and hazards into the structure/system/component (S/S/C) design, (2) add safety devices and capabilities to the designs that reduce risk, (3) provide devices that detect and warn personnel of hazardous conditions, and (4) develop procedures and conduct training to increase worker awareness of potential hazards, on methods to reduce exposure to hazards, and on the actions required to avoid accidents or correct hazardous conditions. The scope of this analysis is limited to the Design Package 1C structures/systems/components (S/S/Cs) during normal operations. Hazards occurring during maintenance and ''off normal'' operations have not been included in this analysis.

  6. Understanding partial bed-load transport: Experiments and stochastic model analysis

    NASA Astrophysics Data System (ADS)

    Sun, HongGuang; Chen, Dong; Zhang, Yong; Chen, Li

    2015-02-01

    The complex dynamics of partial bed-load transport in a series of well-controlled laboratory experiments are explored systematically and simulated by a stochastic model in this study. Flume experiments show that the leading front of bed-load on a 20-m-long, mixed-size gravel-bed moves anomalously, where the transient transport rate of the accelerating front varies with the observation time scale. In addition, observations show that moving particles may experience bimodal transport (i.e., coexistence of long trapping time and large jump length) related to bed coarsening and the formation of clusters on a heterogeneous gravel-bed, which is distinguished from the traditional theory of hiding-exposing interactions among mixed-size particles. A fractional derivative model is finally applied to characterize the overall behavior of partial bed-load transport, including the coexistence of the sub-diffusion and non-local feature caused by turbulence and the micro-relief within an armor layer.

  7. Documentation of Hanford Site independent review of the Hanford Waste Vitrification Plant Preliminary Safety Analysis Report. Revision 3

    SciTech Connect

    Herborn, D.I.

    1993-11-01

    Westinghouse Hanford Company (WHC) is the Integrating Contractor for the Hanford Waste Vitrification Plant (HWVP) Project, and as such is responsible for preparation of the HWVP Preliminary Safety Analysis Report (PSAR). The HWVP PSAR was prepared pursuant to the requirements for safety analyses contained in US Department of Energy (DOE) Orders 4700.1, Project Management System (DOE 1987); 5480.5, Safety of Nuclear Facilities (DOE 1986a); 5481.lB, Safety Analysis and Review System (DOE 1986b) which was superseded by DOE order 5480-23, Nuclear Safety Analysis Reports, for nuclear facilities effective April 30, 1992 (DOE 1992); and 6430.lA, General Design Criteria (DOE 1989). The WHC procedures that, in large part, implement these DOE requirements are contained in WHC-CM-4-46, Nonreactor Facility Safety Analysis Manual. This manual describes the overall WHC safety analysis process in terms of requirements for safety analyses, responsibilities of the various contributing organizations, and required reviews and approvals.

  8. MODEL 9977 B(M)F-96 SAFETY ANALYSIS REPORT FOR PACKAGING

    SciTech Connect

    Abramczyk, G; Paul Blanton, P; Kurt Eberl, K

    2006-05-18

    This Safety Analysis Report for Packaging (SARP) documents the analysis and testing performed on and for the 9977 Shipping Package, referred to as the General Purpose Fissile Package (GPFP). The performance evaluation presented in this SARP documents the compliance of the 9977 package with the regulatory safety requirements for Type B packages. Per 10 CFR 71.59, for the 9977 packages evaluated in this SARP, the value of ''N'' is 50, and the Transport Index based on nuclear criticality control is 1.0. The 9977 package is designed with a high degree of single containment. The 9977 complies with 10 CFR 71 (2002), Department of Energy (DOE) Order 460.1B, DOE Order 460.2, and 10 CFR 20 (2003) for As Low As Reasonably Achievable (ALARA) principles. The 9977 also satisfies the requirements of the Regulations for the Safe Transport of Radioactive Material--1996 Edition (Revised)--Requirements. IAEA Safety Standards, Safety Series No. TS-R-1 (ST-1, Rev.), International Atomic Energy Agency, Vienna, Austria (2000). The 9977 package is designed, analyzed and fabricated in accordance with Section III of the American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel (B&PV) Code, 1992 edition.

  9. Final safety analysis report for the Galileo Mission: Volume 1, Reference design document

    SciTech Connect

    Not Available

    1988-05-01

    The Galileo mission uses nuclear power sources called Radioisotope Thermoelectric Generators (RTGs) to provide the spacecraft's primary electrical power. Because these generators contain nuclear material, a Safety Analysis Report (SAR) is required. A preliminary SAR and an updated SAR were previously issued that provided an evolving status report on the safety analysis. As a result of the Challenger accident, the launch dates for both Galileo and Ulysses missions were later rescheduled for November 1989 and October 1990, respectively. The decision was made by agreement between the DOE and the NASA to have a revised safety evaluation and report (FSAR) prepared on the basis of these revised vehicle accidents and environments. The results of this latest revised safety evaluation are presented in this document (Galileo FSAR). Volume I, this document, provides the background design information required to understand the analyses presented in Volumes II and III. It contains descriptions of the RTGs, the Galileo spacecraft, the Space Shuttle, the Inertial Upper Stage (IUS), the trajectory and flight characteristics including flight contingency modes, and the launch site. There are two appendices in Volume I which provide detailed material properties for the RTG.

  10. Megavariate analysis of environmental QSAR data. Part I – A basic framework founded on principal component analysis (PCA), partial least squares (PLS), and statistical molecular design (SMD)

    Microsoft Academic Search

    Lennart Eriksson; Patrik L. Andersson; Erik Johansson; Mats Tysklind

    2006-01-01

    This paper introduces principal component analysis (PCA), partial least squares projections to latent structures (PLS), and\\u000a statistical molecular design (SMD) as useful tools in deriving multi- and megavariate quantitative structure-activity relationship\\u000a (QSAR) models. Two QSAR data sets from the fields of environmental toxicology and environmental chemistry are worked out in\\u000a detail, showing the benefits of PCA, PLS and SMD. PCA

  11. Statistical analysis of liquid seepage in partially saturated heterogeneous fracture systems

    SciTech Connect

    Liou, T.S.

    1999-12-01

    Field evidence suggests that water flow in unsaturated fracture systems may occur along fast preferential flow paths. However, conventional macroscale continuum approaches generally predict the downward migration of water as a spatially uniform wetting front subjected to strong inhibition into the partially saturated rock matrix. One possible cause of this discrepancy may be the spatially random geometry of the fracture surfaces, and hence, the irregular fracture aperture. Therefore, a numerical model was developed in this study to investigate the effects of geometric features of natural rock fractures on liquid seepage and solute transport in 2-D planar fractures under isothermal, partially saturated conditions. The fractures were conceptualized as 2-D heterogeneous porous media that are characterized by their spatially correlated permeability fields. A statistical simulator, which uses a simulated annealing (SA) algorithm, was employed to generate synthetic permeability fields. Hypothesized geometric features that are expected to be relevant for seepage behavior, such as spatially correlated asperity contacts, were considered in the SA algorithm. Most importantly, a new perturbation mechanism for SA was developed in order to consider specifically the spatial correlation near conditioning asperity contacts. Numerical simulations of fluid flow and solute transport were then performed in these synthetic fractures by the flow simulator TOUGH2, assuming that the effects of matrix permeability, gas phase pressure, capillary/permeability hysteresis, and molecular diffusion can be neglected. Results of flow simulation showed that liquid seepage in partially saturated fractures is characterized by localized preferential flow, along with bypassing, funneling, and localized ponding. Seepage pattern is dominated by the fraction of asperity contracts, and their shape, size, and spatial correlation. However, the correlation structure of permeability field is less important than the spatial correlation of asperity contacts. A faster breakthrough was observed in fractures subjected to higher normal stress, accompanied with a nonlinearly decreasing trend of the effective permeability. Interestingly, seepage dispersion is generally higher in fractures with intermediate fraction of asperity contacts; but it is lower for small or large fractions of asperity contacts. However, it may become higher if the ponding becomes significant. Transport simulations indicate that tracers bypass dead-end pores and travel along flow paths that have less flow resistance. Accordingly, tracer breakthrough curves generally show more spreading than breakthrough curves for water. Further analyses suggest that the log-normal time model generally fails to fit the breakthrough curves for water, but it is a good approximation for breakthrough curves for the tracer.

  12. The Range Safety Debris Catalog Analysis in Preparation for the Pad Abort One Flight Test

    NASA Technical Reports Server (NTRS)

    Kutty, Prasad M.; Pratt, William D.

    2010-01-01

    The Pad Abort One flight test of the Orion Abort Flight Test Program is currently under development with the goal of demonstrating the capability of the Launch Abort System. In the event of a launch failure, this system will propel the Crew Exploration Vehicle to safety. An essential component of this flight test is range safety, which ensures the security of range assets and personnel. A debris catalog analysis was done as part of a range safety data package delivered to the White Sands Missile Range in New Mexico where the test will be conducted. The analysis discusses the consequences of an overpressurization of the Abort Motor. The resulting structural failure was assumed to create a debris field of vehicle fragments that could potentially pose a hazard to the range. A statistical model was used to assemble the debris catalog of potential propellant fragments. Then, a thermodynamic, energy balance model was applied to the system in order to determine the imparted velocity to these propellant fragments. This analysis was conducted at four points along the flight trajectory to better understand the failure consequences over the entire flight. The methods used to perform this analysis are outlined in detail and the corresponding results are presented and discussed.

  13. Analysis and simulation of a fiber bundle method for creating a partially spatially coherent beam.

    PubMed

    Xiao, Xifeng; Voelz, David

    2013-08-10

    A fiber bundle arrangement containing a distribution of fiber lengths has been proposed in the literature to produce a partially spatially coherent beam. Light input to the bundle with limited temporal coherence is translated into limited spatial coherence. Expressions are developed for the bundle pupil autocorrelation function and far-field irradiance pattern. A numerical simulation approach is implemented and results are compared with a speckle-free result. The fiber bundle approach tends to create an irradiance pattern whose average shape matches the pattern produced by a single fiber. A "smoothed" far-field pattern is obtained if the fiber length difference is much greater than the source temporal coherence length. PMID:23938434

  14. Analysis of Photovoltaic (PV) Module during Partial Shading based on Simplified Two-Diode Model

    NASA Astrophysics Data System (ADS)

    Chitti Babu, B.; Gurjar, Suresh; Meher, Ashish

    2015-02-01

    Generally, the characteristics of photovoltaic (PV) array are largely affected by solar temperature, solar irradiance, shading patterns, array configuration and location of shading modules. Partial shading is due to moving clouds and shadows of nearby obstacles and can cause a significant degradation in the output of PV system. Hence, the characteristics of PV array get more multifaceted with multiple peaks. The ultimate aim of the paper is to analyze the performance of PV module during such adverse condition based on simplified two-diode model. To reduce the computational time, the simplified two-diode model has a photocurrent source in parallel with two ideal diodes. Only four parameters are required to be calculated from datasheet in order to simulate the model. Moreover, the performance of PV array is evaluated at different shaded patterns and it is found that the model has less computational time and gives accurate results.

  15. Automating Embedded Analysis Capabilities and Managing Software Complexity in Multiphysics Simulation, Part II: Application to Partial Differential Equations

    DOE PAGESBeta

    Pawlowski, Roger P.; Phipps, Eric T.; Salinger, Andrew G.; Owen, Steven J.; Siefert, Christopher M.; Staten, Matthew L.

    2012-01-01

    A template-based generic programming approach was presented in Part I of this series of papers [Sci. Program. 20 (2012), 197–219] that separates the development effort of programming a physical model from that of computing additional quantities, such as derivatives, needed for embedded analysis algorithms. In this paper, we describe the implementation details for using the template-based generic programming approach for simulation and analysis of partial differential equations (PDEs). We detail several of the hurdles that we have encountered, and some of the software infrastructure developed to overcome them. We end with a demonstration where we present shape optimization and uncertaintymore »quantification results for a 3D PDE application.« less

  16. Macroergonomics and patient safety: The impact of levels on theory, measurement, analysis and intervention in patient safety research

    Microsoft Academic Search

    Ben-Tzion Karsh; Roger Brown

    2010-01-01

    The study and practice of patient safety has seen a surge over the last 10 years. New resident training and staffing policies, health information technologies, error reporting systems, team models of care, training methods, patient involvement, information handoff strategies, just cultures, and many other interventions have been mandated or attempted to improve the safety of patient care. While some of

  17. Computing Expected Value of Partial Sample Information from Probabilistic Sensitivity Analysis Using Linear Regression Metamodeling.

    PubMed

    Jalal, Hawre; Goldhaber-Fiebert, Jeremy D; Kuntz, Karen M

    2015-07-01

    Decision makers often desire both guidance on the most cost-effective interventions given current knowledge and also the value of collecting additional information to improve the decisions made (i.e., from value of information [VOI] analysis). Unfortunately, VOI analysis remains underused due to the conceptual, mathematical, and computational challenges of implementing Bayesian decision-theoretic approaches in models of sufficient complexity for real-world decision making. In this study, we propose a novel practical approach for conducting VOI analysis using a combination of probabilistic sensitivity analysis, linear regression metamodeling, and unit normal loss integral function-a parametric approach to VOI analysis. We adopt a linear approximation and leverage a fundamental assumption of VOI analysis, which requires that all sources of prior uncertainties be accurately specified. We provide examples of the approach and show that the assumptions we make do not induce substantial bias but greatly reduce the computational time needed to perform VOI analysis. Our approach avoids the need to analytically solve or approximate joint Bayesian updating, requires only one set of probabilistic sensitivity analysis simulations, and can be applied in models with correlated input parameters. PMID:25840900

  18. A probabilistic safety analysis of UF{sub 6} handling at the Portsmouth Gaseous Diffusion Plant

    SciTech Connect

    Boyd, G.J.; Lewis, S.R.; Summitt, R.L. [Safety and Reliability Optimization Services (SAROS), Inc., Knoxville, TN (United States)

    1991-12-31

    A probabilistic safety study of UF{sub 6} handling activities at the Portsmouth Gaseous Diffusion Plant has recently been completed. The analysis provides a unique perspective on the safety of UF{sub 6} handling activities. The estimated release frequencies provide an understanding of current risks, and the examination of individual contributors yields a ranking of important plant features and operations. Aside from the probabilistic results, however, there is an even more important benefit derived from a systematic modeling of all operations. The integrated approach employed in the analysis allows the interrelationships among the equipment and the required operations to be explored in depth. This paper summarizes the methods used in the study and provides an overview of some of the technical insights that were obtained. Specific areas of possible improvement in operations are described.

  19. Safety analysis report for the Heavy-Element Facility (Building 251), Lawrence Livermore National Laboratory

    SciTech Connect

    Kvam, D.J.

    1982-10-11

    A comprehensive safety analysis was performed on the Lawrence Livermore National Laboratory's Heavy Element Facility, Building 251. The purpose of the analysis was to evaluate the building and its operations in order to inform LLNL and the Department of Energy of the risks they assume at Building 251. This was done by examining all of the energy sources and matching them with the physical and administrative barriers that control, prevent, or mitigate their hazards. Risk was evaluated for each source under both normal and catastrophic circumstances such as fire, flood, high wind, lighting, earthquake, and criticality. No significant safety deficiencies were found; it is concluded that the operation of the facility presents no unacceptable risk.

  20. Bidirectional Analysis for Certification of SafetyCritical Software Robyn R. Lutz \\Lambda and Robert M. Woodhouse y

    E-print Network

    Lutz, Robyn R.

    Bi­directional Analysis for Certification of Safety­Critical Software Robyn R. Lutz \\Lambda and Robert M. Woodhouse y Jet Propulsion Laboratory California Institute of Technology Pasadena, CA 91109 for software safety. 1 Introduction Even as requirements for software certification pro­ liferate, the best

  1. Development of the Pharmacy Safety Climate Questionnaire: a principal components analysis

    Microsoft Academic Search

    D M Ashcroft; D Parker

    2009-01-01

    Objective:To develop, and examine the component structure and internal consistency, of a questionnaire designed to assess safety climate in the community pharmacy setting.Methods:998 pharmacists working in community pharmacies in England completed the questionnaire. Item selection was determined by principal components analysis (PCA) which also defined the underlying structure of the questionnaire. Scales were constructed from the items that loaded on

  2. An Economic Analysis of Food Safety Issues Following the SPS Agreement: Lessons from the Hormones Dispute

    Microsoft Academic Search

    Sallie James

    2000-01-01

    AN ECONOMIC ANALYSIS OF FOOD SAFETY ISSUESFOLLOWING THE SPS AGREEMENT:LESSONS FROM THE HORMONES DISPUTESallie JamesThe long-running feud between the US and the EU over trade in hormone-treated beefwas the first case under the Uruguay Round's SPS Agreement to be disputed formally atthe WTO. It provides a classic example of how cultural differences with respect to foodattributes have the potential to

  3. Use and safety of anthroposophic medications in chronic disease: A two-year prospective analysis

    Microsoft Academic Search

    Harald J. Hamre; Claudia M. Witt; Anja Glockmann; Wilfried Tröger

    Background and objective: Anthroposophic medications (AMED) are prescribed by physicians in 56 countries worldwide and are used for the treatment of a variety of conditions. However, safety data on long-term use of AMED from large prospective studies are sparse. The objective of this analysis was to determine the frequency of patient-reported and physician-assessed adverse drug reactions (ADRs) from AMED in

  4. Thermodynamic properties and equations of state for fast reactor safety analysis

    Microsoft Academic Search

    K Morita; E. A Fischer; K Thurnay

    1998-01-01

    In this paper, thermodynamic properties of reactor-core materials are newly evaluated for an analytic equation-of-state (EOS) model with flexible thermodynamic functions. This model has been developed for a multiphase, multicomponent fluid-dynamics code for fast reactor safety analysis. The most up-to-date and reliable sources for uranium dioxide, mixed-oxide fuel, stainless steel, and sodium available at present are first compiled, with particular

  5. 76 FR 47085 - Domestic Licensing of Source Material-Amendments/Integrated Safety Analysis; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    The U.S. Nuclear Regulatory Commission (NRC) is correcting a notice appearing in the Federal Register on July 27, 2011 (76 FR 44865), that extended the public comment period and provided a date for a public meeting for the proposed rule, ``Domestic Licensing of Source Material--Amendments/Integrated Safety Analysis.'' This action is necessary to correct the date of the public meeting in the DATES......

  6. Structural analysis and safety assessment of submerged floating tunnel prototype in Qiandao Lake (China)

    Microsoft Academic Search

    Shuangyin Zhang; Lei Wang; Youshi Hong

    2010-01-01

    This article presents the structural analysis and the safety assessment of the submerged floating tunnel (SFT) prototype, which is designed to be built in Qiandao Lake (China). Based on the principle of bending stiffness equivalence, a homogenized equivalent single-layered-tube model is established. The effective beam bending stiffness and the corresponding Young’s modulus are deduced. By using lamination theory of composite

  7. Partial derivative—Based sensitivity analysis of models describing target-mediated drug disposition

    Microsoft Academic Search

    Anson K. Abraham; Wojciech Krzyzanski; Donald E. Mager

    2007-01-01

    Sensitivity analysis is commonly used to characterize the effects of parameter perturbations on model output. One use for\\u000a the approach is the optimization of an experimental design enabling estimation of model parameters with improved accuracy.\\u000a The primary objective of this study is to conduct a sensitivity analysis of selected target-mediated pharmacokinetic models,\\u000a ascertain the effect of parameter variations on model

  8. Phylogenetic analysis of canine parvovirus partial VP2 gene in India.

    PubMed

    Mukhopadhyay, H K; Matta, Samyukta Lakshmi; Amsaveni, S; Antony, P X; Thanislass, J; Pillai, R M

    2014-02-01

    A total of 85 samples (58.0 %) were found to be positive for Canine parvovirus (CPV) by PCR assay (Hfor/Hrev primers) out of 158 suspected faecal samples of dogs collected from various states/union territories of India. Nine CPV isolates could be obtained in A-72 cell line. The sequencing of the partial VP2 gene of CPV identified the predominant CPV strain as CPV-2a (Ser297Ala) with one CPV-2b (Ser297Ala) and another CPV-2a variant strain (Ser297Gly). Several non-synonymous and synonymous mutations were also recorded in this study. The phylogenetic tree revealed that most of the CPV sequences from Tamil Nadu (Southern India) and Maharashtra (Western India) obtained during 2011 and few sequences from Northern India obtained during 2012 were grouped together along with CPV-2a (Ser297Ala) strains from China and India and followed the same evolution; although there was definitive indication of separate lineages too by few other sequences. PMID:24174279

  9. [Vibration analysis of maxillary removable partial denture using three types of major connectors].

    PubMed

    Naoki, Matsumoto

    2003-06-01

    This study investigated the effect on the vibratory characteristics of a Class I Kennedy maxillary removable partial denture when varying its major connector design. Three types of major connector were used: the U-shaped palatal connector type (UPCD), the single palatal bar type (SPBD), and the anterior-posterior palatal bars type (APBD). Three types of denture were excited by a shaker, and frequency response functions were recorded on an FFT analyzer to identify their modal shapes. In addition, transient response simulations were carried out and the maximum displacement of each denture was obtained. The maximum displacements were statistically analyzed by ANOVA and Scheffe's F test (p < 0.01). In the modal shapes of SPBD, there were no nodal points on the major connector at all natural modes. The maximum displacement of SPBD was significantly smaller than that of UPCD and APBD. This study indicated that SPBD was a more rigid design than UPCD and APBD from the standpoint of vibratory characteristics. PMID:12872748

  10. Periodontal ligament influence on the stress distribution in a removable partial denture supported by implant: a finite element analysis

    PubMed Central

    ARCHANGELO, Carlos Marcelo; ROCHA, Eduardo Passos; PEREIRA, João Antônio; MARTIN JUNIOR, Manoel; ANCHIETA, Rodolfo Bruniera; FREITAS JÚNIOR, Amilcar Chagas

    2012-01-01

    ABSTRACT Objective The non-homogenous aspect of periodontal ligament (PDL) has been examined using finite element analysis (FEA) to better simulate PDL behavior. The aim of this study was to assess, by 2-D FEA, the influence of non-homogenous PDL on the stress distribution when the free-end saddle removable partial denture (RPD) is partially supported by an osseointegrated implant. Material and Methods Six finite element (FE) models of a partially edentulous mandible were created to represent two types of PDL (non-homogenous and homogenous) and two types of RPD (conventional RPD, supported by tooth and fibromucosa; and modified RPD, supported by tooth and implant [10.00x3.75 mm]). Two additional FE models without RPD were used as control models. The non-homogenous PDL was modeled using beam elements to simulate the crest, horizontal, oblique and apical fibers. The load (50 N) was applied in each cusp simultaneously. Regarding boundary conditions the border of alveolar ridge was fixed along the x axis. The FE software (Ansys 10.0) was used to compute the stress fields, and the von Mises stress criterion (?vM) was applied to analyze the results. Results The peak of ?vM in non-homogenous PDL was higher than that for the homogenous condition. The benefits of implants were enhanced for the non-homogenous PDL condition, with drastic ?vM reduction on the posterior half of the alveolar ridge. The implant did not reduce the stress on the support tooth for both PDL conditions. Conclusion The PDL modeled in the non-homogeneous form increased the benefits of the osseointegrated implant in comparison with the homogeneous condition. Using the non-homogenous PDL, the presence of osseointegrated implant did not reduce the stress on the supporting tooth. PMID:22858705

  11. Photoelastic stress analysis of different designs of cement-retained fixed partial dentures on Morse taper oral implants.

    PubMed

    Menani, Luiz Ricardo; Tiossi, Rodrigo; de Torres, Érica Miranda; Ribeiro, Ricardo Faria; de Almeida, Rossana Pereira

    2011-03-01

    There is no consensus in literature regarding the best plan for prosthetic rehabilitation with partial multiple adjacent implants to minimize stress generated in the bone-implant interface. The aim of this study was to evaluate the biomechanical behavior of cemented fixed partial dentures, splinted and nonsplinted, on Morse taper implants and with different types of coating material (ceramic and resin), using photoelastic stress analysis. A photoelastic model of an interposed edentulous space, missing a second premolar and a first molar, and rehabilitated with 4 different types of cemented crowns and supported by 2 adjacent implants was used. Groups were as follows: UC, splinted ceramic crowns; IC, nonsplinted ceramic crowns; UR, splinted resin crowns; and IR, nonsplinted resin crowns. Different vertical static loading conditions were performed: balanced occlusal load, 10 kgf; simultaneous punctiform load on the implanted premolar and molar, 10 kgf; and alternate punctiform load on the implanted premolar and molar, 5 kgf. Changes in stress distribution were analyzed in a polariscope, and digital photographs were taken of each condition to allow comparison of stress pattern distribution around the implants. Cementation of the fixed partial dentures generated stresses between implants. Splinted restorations distributed the stresses more evenly between the implants than nonsplinted when force was applied. Ceramic restorations presented better distribution of stresses than resin restorations. Based on the results obtained, it was concluded that splinted ceramic restorations promote better stress distribution around osseointegrated implants when compared with nonsplinted crowns; metal-ceramic restorations present less stress concentration and magnitude than metal-plastic restorations. PMID:21415635

  12. Analysis of governmental Web sites on food safety issues: a global perspective.

    PubMed

    Namkung, Young; Almanza, Barbara A

    2006-10-01

    Despite a growing concern over food safety issues, as well as a growing dependence on the Internet as a source of information, little research has been done to examine the presence and relevance of food safety-related information on Web sites. The study reported here conducted Web site analysis in order to examine the current operational status of governmental Web sites on food safety issues. The study also evaluated Web site usability, especially information dimensionalities such as utility, currency, and relevance of content, from the perspective of the English-speaking consumer. Results showed that out of 192 World Health Organization members, 111 countries operated governmental Web sites that provide information about food safety issues. Among 171 searchable Web sites from the 111 countries, 123 Web sites (71.9 percent) were accessible, and 81 of those 123 (65.9 percent) were available in English. The majority of Web sites offered search engine tools and related links for more information, but their availability and utility was limited. In terms of content, 69.9 percent of Web sites offered information on foodborne-disease outbreaks, compared with 31.5 percent that had travel- and health-related information. PMID:17066944

  13. [Social network analysis: a method to improve safety in healthcare organizations].

    PubMed

    Marqués Sánchez, Pilar; González Pérez, Marta Eva; Agra Varela, Yolanda; Vega Núñez, Jorge; Pinto Carral, Arrate; Quiroga Sánchez, Enedina

    2013-01-01

    Patient safety depends on the culture of the healthcare organization involving relationships between professionals. This article proposes that the study of these relations should be conducted from a network perspective and using a methodology called Social Network Analysis (SNA). This methodology includes a set of mathematical constructs grounded in Graph Theory. With the SNA we can know aspects of the individual's position in the network (centrality) or cohesion among team members. Thus, the SNA allows to know aspects related to security such as the kind of links that can increase commitment among professionals, how to build those links, which nodes have more prestige in the team in generating confidence or collaborative network, which professionals serve as intermediaries between the subgroups of a team to transmit information or smooth conflicts, etc. Useful aspects in stablishing a safety culture. The SNA would analyze the relations among professionals, their level of communication to communicate errors and spontaneously seek help and coordination between departments to participate in projects that enhance safety. Thus, they related through a network, using the same language, a fact that helps to build a culture. In summary, we propose an approach to safety culture from a SNA perspective that would complement other commonly used methods. PMID:23892673

  14. Safety analysis of the CSTR-1 bench-scale coal liquefaction unit

    SciTech Connect

    Hulburt, D.A.

    1981-05-01

    The objective of the program reported herein was to provide a Safety Analysis of the CSTR-1 bench scale unit located in Building 167 at the Pittsburgh Energy Technology Center. It was apparent that considerable effort was expended in the design and construction of the unit, and in the development of operating procedures, with regard to safety. Exhaust ventilation, H/sub 2/ and H/sub 2/S monitoring, overpressure protection, overtemperature protection, and interlock systems have been provided. Present settings on the pressure and temperature safety systems are too high, however, to insure prevention of vessel deformation or damage in all cases. While the occurrence of catastrophic rupture of a system pressure vessel (e.g., reactor, high pressure separators) is unlikely, the potential consequences to personnel are severe. Feasibility of providing shielding for these components should be considered. A more probable mode of vessel failure in the event of overpressure or overtemperature and failure of the safety system is yielding of the closure bolts followed by high pressure flow across the mating surfaces. As a minimum, shielding should be designed to restrict travel of resultant spray. The requirements for personal protective equipment are presently stated in rather broad and general terms in the operating procedures. Safe practices and procedures would be more assured if specific requirements were stated and included for each operational step. Recommendations were developed for all hazards triggered by the guidelines.

  15. The use of experimental data in an MTR-type nuclear reactor safety analysis

    NASA Astrophysics Data System (ADS)

    Day, Simon E.

    Reactivity initiated accidents (RIAs) are a category of events required for research reactor safety analysis. A subset of this is unprotected RIAs in which mechanical systems or human intervention are not credited in the response of the system. Light-water cooled and moderated MTR-type ( i.e., aluminum-clad uranium plate fuel) reactors are self-limiting up to some reactivity insertion limit beyond which fuel damage occurs. This characteristic was studied in the Borax and Spert reactor tests of the 1950s and 1960s in the USA. This thesis considers the use of this experimental data in generic MTR-type reactor safety analysis. The approach presented herein is based on fundamental phenomenological understanding and uses correlations in the reactor test data with suitable account taken for differences in important system parameters. Specifically, a semi-empirical approach is used to quantify the relationship between the power, energy and temperature rise response of the system as well as parametric dependencies on void coefficient and the degree of subcooling. Secondary effects including the dependence on coolant flow are also examined. A rigorous curve fitting approach and error assessment is used to quantify the trends in the experimental data. In addition to the initial power burst stage of an unprotected transient, the longer term stability of the system is considered with a stylized treatment of characteristic power/temperature oscillations (chugging). A bridge from the HEU-based experimental data to the LEU fuel cycle is assessed and outlined based on existing simulation results presented in the literature. A cell-model based parametric study is included. The results are used to construct a practical safety analysis methodology for determining reactivity insertion safety limits for a light-water moderated and cooled MTR-type core.

  16. Greater Trochanteric Fixation Using a Cable System for Partial Hip Arthroplasty: A Clinical and Finite Element Analysis

    PubMed Central

    Ozan, F?rat; Koyuncu, ?emmi; Pekedis, Mahmut; Altay, Ta?k?n; Y?ld?z, Hasan; Toker, Gökhan

    2014-01-01

    The aim of the study was to investigate the efficacy of greater trochanteric fixation using a multifilament cable to ensure abductor lever arm continuity in patients with a proximal femoral fracture undergoing partial hip arthroplasty. Mean age of the patients (12 men, 20 women) was 84.12 years. Mean follow-up was 13.06 months. Fixation of the dislocated greater trochanter with or without a cable following load application was assessed by finite element analysis (FEA). Radiological evaluation was based on the distance between the fracture and the union site. Harris hip score was used to evaluate final results: outcomes were excellent in 7 patients (21.8%), good in 17 patients (53.1%), average in 5 patients (15.6%), and poor in 1 patient (9.3%). Mean abduction angle was 20.21°. Union was achieved in 14 patients (43.7%), fibrous union in 12 (37.5%), and no union in 6 (18.7%). FEA showed that the maximum total displacement of the greater trochanter decreased when the fractured bone was fixed with a cable. As the force applied to the cable increased, the displacement of the fractured trochanter decreased. This technique ensures continuity of the abductor lever arm in patients with a proximal femoral fracture who are undergoing partial hip arthroplasty surgery. PMID:25177703

  17. Partial Breast Irradiation Versus Whole Breast Radiotherapy for Early-Stage Breast Cancer: A Decision Analysis

    SciTech Connect

    Sher, David J. [Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA (United States); Wittenberg, Eve [Institute for Technology Assessment, Massachusetts General Hospital, Boston, MA (United States); Taghian, Alphonse G. [Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA (United States); Bellon, Jennifer R. [Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA (United States); Punglia, Rinaa S. [Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA (United States)], E-mail: rpunglia@lroc.harvard.edu

    2008-02-01

    Purpose: To compare the quality-adjusted life expectancy between women treated with partial breast irradiation (PBI) vs. whole breast radiotherapy (WBRT) for estrogen receptor-positive early-stage breast cancer. Methods and Materials: We developed a Markov model to describe health states in the 15 years after radiotherapy for estrogen receptor-positive early-stage breast cancer. Breast cancer recurrences were separated into local recurrences and elsewhere failures. Ipsilateral breast tumor recurrence (IBTR) risk was extracted from the Oxford overview, and rates and utilities were adapted from the literature. We studied two cohorts of women (aged 40 and 55 years), both of whom received adjuvant tamoxifen. Results: Assuming a no evidence of disease (NED)-PBI utility of 0.93, quality-adusted life expectancy after PBI (and WBRT) was 12.61 (12.57) and 12.10 (12.06) years for 40-year-old and 55-year-old women, respectively. The NED-PBI utility thresholds for preferring PBI over WBRT were 0.923 and 0.921 for 40-year-old and 55-year-old women, respectively, both slightly greater than the NED-WBRT utility. Outcomes were sensitive to the utility of NED-PBI, the PBI hazard ratio for local recurrence, the baseline IBTR risk, and the percentage of IBTRs that were local. Overall the degree of superiority of PBI over WBRT was greater for 55-year-old women than for 40-year-old women. Conclusions: For most utility values of the NED-PBI health state, PBI was the preferred treatment modality. This result was highly sensitive to patient preferences and was also dependent on patient age, PBI efficacy, IBTR risk, and the fraction of IBTRs that were local.

  18. Analysis of partially observed clustered data using generalized estimating equations and multiple imputation

    PubMed Central

    Aloisio, Kathryn M.; Swanson, Sonja A.; Micali, Nadia; Field, Alison; Horton, Nicholas J.

    2015-01-01

    Clustered data arise in many settings, particularly within the social and biomedical sciences. As an example, multiple–source reports are commonly collected in child and adolescent psychiatric epidemiologic studies where researchers use various informants (e.g. parent and adolescent) to provide a holistic view of a subject’s symptomatology. Fitzmaurice et al. (1995) have described estimation of multiple source models using a standard generalized estimating equation (GEE) framework. However, these studies often have missing data due to additional stages of consent and assent required. The usual GEE is unbiased when missingness is Missing Completely at Random (MCAR) in the sense of Little and Rubin (2002). This is a strong assumption that may not be tenable. Other options such as weighted generalized estimating equations (WEEs) are computationally challenging when missingness is non–monotone. Multiple imputation is an attractive method to fit incomplete data models while only requiring the less restrictive Missing at Random (MAR) assumption. Previously estimation of partially observed clustered data was computationally challenging however recent developments in Stata have facilitated their use in practice. We demonstrate how to utilize multiple imputation in conjunction with a GEE to investigate the prevalence of disordered eating symptoms in adolescents reported by parents and adolescents as well as factors associated with concordance and prevalence. The methods are motivated by the Avon Longitudinal Study of Parents and their Children (ALSPAC), a cohort study that enrolled more than 14,000 pregnant mothers in 1991–92 and has followed the health and development of their children at regular intervals. While point estimates were fairly similar to the GEE under MCAR, the MAR model had smaller standard errors, while requiring less stringent assumptions regarding missingness. PMID:25642154

  19. Genetic analysis of loci associated with partial resistance to Sclerotinia sclerotiorum in rapeseed (Brassica napus L.).

    PubMed

    Zhao, Jianwei; Meng, Jinling

    2003-02-01

    Sclerotinia stem rot is the most devastating disease of rapeseed (Brassica napus L.) in China. Quantitative trait loci (QTLs) involved in resistance to Sclerotinia sclerotiorum were detected in a rapeseed population of 128-F(2:3) families derived from a cross between the male sterility restorer line H5200 and a partial resistant line Ning RS-1. A total of 107 molecular markers including 72 RFLPs, 30 AFLPs, 3 SSRs and 2 RAPDs were employed to construct a genetic linkage map with 23 linkage groups covering 1,625.7 cM with an average space of 15.2 cM. Resistance was assessed empirically at two developmental stages: with a detached leaf inoculation at the seedling stage and in vivo stem inoculation at the mature plant stage. The observed resistance was scored for each plant as leaf resistance at the seedling stage (LRS) and stem resistance at the mature plant stage (SRM). A total of 13 loci were identified by one-way ANOVA and six QTLs were detected with MapMaker-QTL. We found that three of the six QTLs were associated with leaf resistance at the seedling stage and collectively accounted for 40.7% of the total phenotypic variation, each accounting for 23.2%, 16.6% and 13.6% respectively. Three QTLs were found corresponding to the disease resistance at the mature plant stage, explaining 49.0% of the phenotypic variation. Epistasis was observed for the resistance and the additive by additive interactions were the predominant type of epistasis. It was concluded that both single-locus QTLs and epistatic interactions played important roles in Sclerotinia resistance in rapeseed. PMID:12596007

  20. Quantitative analysis of reptation of partially extended DNA in sub-30 nm nanoslits

    E-print Network

    Yeh, Jia-Wei; Taloni, Alessandro; Chen, Yeng-Long; Chou, Chia-Fu

    2015-01-01

    We observed reptation of single DNA molecules in fused silica nanoslits of sub-30 nm height. The reptation behavior and the effect of confinement are quantitatively characterized using orientation correlation and transverse fluctuation analysis. We show tube-like polymer motion arises for a tense polymer under strong quasi-2D confinement and interaction with surface- passivating polyvinylpyrrolidone (PVP) molecules in nanoslits, while etching- induced device surface roughness, chip bonding materials and DNA-intercalated dye-surface interaction, play minor roles. These findings have strong implications for the effect of surface modification in nanofluidic systems with potential applications for single molecule DNA analysis.

  1. Quantitative analysis of reptation of partially extended DNA in sub-30 nm nanoslits

    E-print Network

    Jia-Wei Yeh; K. K. Sriram; Alessandro Taloni; Yeng-Long Chen; Chia-Fu Chou

    2015-02-18

    We observed reptation of single DNA molecules in fused silica nanoslits of sub-30 nm height. The reptation behavior and the effect of confinement are quantitatively characterized using orientation correlation and transverse fluctuation analysis. We show tube-like polymer motion arises for a tense polymer under strong quasi-2D confinement and interaction with surface- passivating polyvinylpyrrolidone (PVP) molecules in nanoslits, while etching- induced device surface roughness, chip bonding materials and DNA-intercalated dye-surface interaction, play minor roles. These findings have strong implications for the effect of surface modification in nanofluidic systems with potential applications for single molecule DNA analysis.

  2. Case-control analysis in highway safety: Accounting for sites with multiple crashes.

    PubMed

    Gross, Frank

    2013-12-01

    There is an increased interest in the use of epidemiological methods in highway safety analysis. The case-control and cohort methods are commonly used in the epidemiological field to identify risk factors and quantify the risk or odds of disease given certain characteristics and factors related to an individual. This same concept can be applied to highway safety where the entity of interest is a roadway segment or intersection (rather than a person) and the risk factors of interest are the operational and geometric characteristics of a given roadway. One criticism of the use of these methods in highway safety is that they have not accounted for the difference between sites with single and multiple crashes. In the medical field, a disease either occurs or it does not; multiple occurrences are generally not an issue. In the highway safety field, it is necessary to evaluate the safety of a given site while accounting for multiple crashes. Otherwise, the analysis may underestimate the safety effects of a given factor. This paper explores the use of the case-control method in highway safety and two variations to account for sites with multiple crashes. Specifically, the paper presents two alternative methods for defining cases in a case-control study and compares the results in a case study. The first alternative defines a separate case for each crash in a given study period, thereby increasing the weight of the associated roadway characteristics in the analysis. The second alternative defines entire crash categories as cases (sites with one crash, sites with two crashes, etc.) and analyzes each group separately in comparison to sites with no crashes. The results are also compared to a "typical" case-control application, where the cases are simply defined as any entity that experiences at least one crash and controls are those entities without a crash in a given period. In a "typical" case-control design, the attributes associated with single-crash segments are weighted the same as the attributes of segments with multiple crashes. The results support the hypothesis that the "typical" case-control design may underestimate the safety effects of a given factor compared to methods that account for sites with multiple crashes. Compared to the first alternative case definition (where multiple crash segments represent multiple cases) the results from the "typical" case-control design are less pronounced (i.e., closer to unity). The second alternative (where case definitions are constructed for various crash categories and analyzed separately) provides further evidence that sites with single and multiple crashes should not be grouped together in a case-control analysis. This paper indicates a clear need to differentiate sites with single and multiple crashes in a case-control analysis. While the results suggest that sites with multiple crashes can be accounted for using a case-control design, further research is needed to determine the optimal method for addressing this issue. This paper provides a starting point for that research. PMID:22682970

  3. The Design Analysis Re-engineering Tool—for design basis justification and safety related information management

    Microsoft Academic Search

    A Billington; P Blondiaux; J Boucau; B Cantineau; A Mared

    1999-01-01

    DART is the acronym for the Design Analysis Re-engineering Tool. It embodies a systematic and integrated approach to NPP safety re-assessment and configuration management, that makes use of reverse failure mode and effect analysis in conjunction with a state-of-the-art relational database and a standardized data format, to permit long-term management of plant safety related information. The plant design is reviewed

  4. Analysis of hot-spot-effects in encapsulated photovoltaic generators by laser scan and partial shadowing

    Microsoft Academic Search

    G. H. Hewig; H.-P. Huebner

    1982-01-01

    Theoretical and experimental analysis were carried out on the sensitivity of encapsulated solar cell power generators to the appearance of hot spots. It is noted that mass produced solar cells, even if inspected before installation in a sealed module, will display small variations in the IV characteristics of individual cells. The IV curve for the entire generator is expressed as

  5. A Riemannian Analysis of 3D Nose Shapes For Partial Human Biometrics Hassen drira

    E-print Network

    Paris-Sud XI, Université de

    been motivated by security applications, one can safely expect an exponential growth in a general use of bio- metrics in our increasingly digital society. By human bio- metrics we mean the use information, such that their joint analysis may succeed for large populations. This has led to the notion

  6. Reliability analysis of k-out-of-n systems with partially repairable multi-state components

    Microsoft Academic Search

    A. Suprasad; R. B. Misra

    1996-01-01

    In some environments the components might not fail fully, but can lead to degradation and the efficiency of the system may decreases. However, the degraded components can be restored back through a proper repair mechanism. In this paper, we present a model to perform reliability analysis of k-out-of-n systems assuming that components are subjected to three states such as good,

  7. SAFETY ANALYSIS FOR TANK 241-AZ-101 MIXER PUMP PROCESS TEST

    SciTech Connect

    HAMMOND DM; HARRIS JP; MOUETTE P

    1997-06-09

    This document contains the completed safety analysis which establishes the safety envelope for performing the mixer pump process test in Tank 241-AZ-101. This process test is described in TF-210-OTP-001. All equipment necessary for the mixer pump test has been installed by Project W-151. The purpose of this document is to describe and analyze the mixer pump test for Aging Waste Facility (AWF) Tank 241-AZ-101 and to address the 'yes/maybe' responses marked for evaluation questions identified in Unreviewed Safety Question Evaluation (USQE) TF-94-0266. The scope of this document is limited to the performance of the mixer pump test for Tank 241-AZ-101. Unreviewed Safety Question Determination (USQD) TF-96-0018 verified that the installation of two mixer pumps into Tank 241-AZ-101 was within the current Tank Waste Remediation System (TWRS) Authorization Basis. USQDs TF-96-0461, TF-96-0448, and TF-96-0805 verified that the installation of the in-tank video camera, thermocouples, and Ultrasonic Interface Level Analyzer (URSILLA), respectively, were within the current TWRS Authorization Basis. USQD TF-96-1041 verified that the checkout testing of the installed equipment was within the current TWRS Authorization Basis. Installation of the pumps and equipment has been completed. An evaluation of safety considerations associated with operation of the mixer pumps for the mixer pump test is provided in this document. This document augments the existing AWF authorization basis as defined in the Interim Safety Basis (Stahl 1997), and as such, will use the existing Interim Operational Safety Requirements (IOSRs) of Heubach 1996 to adequately control the mixer pump test. The hazard and accident analysis is limited to the scope and impact of the mixer pump test, and therefore does not address hazards already addressed by the current AWF authorization basis. This document does not evaluate removal of the mixer pumps. Safety considerations for removal of the pumps will be addressed by separate safety documentation once that portion of the mission is defined. The mixer pump test has been evaluated to cover the use of either the existing ventilation system (241-A-702) or the ventilation system upgrade provided by Project W-030. Analysis of Project W-030 is outside of the scope of this document and is addressed in HNF-SD-WM-SARR-039 (Draft) which, should the W-030 system be in service at the time of the mixer pump test, will have been approved and made a part of the TWRS authorization basis. The test will use two high-capacity mixer pumps in various configurations and modes to demonstrate solids mobilization of waste in Tank 241-AZ-101. The information and experience gained during the test will provide data for comparison with sludge mobilization prediction models; provide data to estimate the number, location, and cycle times of the mixer pumps; and provide indication of the effects of mixer pump operation on the AWF tank systems and components. The slurry produced will be evaluated for future pretreatment processing. This process test does not transfer waste from the tank; the waste is mixed and confined within the existing system. At the completion of the mixer pump test, the mixer pumps will be stopped and normal tank operations, maintenance, and surveillance will continue. Periodic rotation of the mixer pumps and motor shafts, along with bearing greasing, is required to maintain the pumps following the mixer pump test.

  8. Organic Tanks Safety Program: Advanced organic analysis FY 1996 progress report

    SciTech Connect

    NONE

    1996-09-01

    Major focus during the first part of FY96 was to evaluate using organic functional group concentrations to screen for energetics. Fourier transform infrared and Raman spectroscopy would be useful screening tools for determining C-H and COO- organic content in tank wastes analyzed in a hot cell. These techniques would be used for identifying tanks of potential safety concern that may require further analysis. Samples from Tanks 241-C-106 and -C-204 were analyzed; the major organic in C-106 was B2EHPA and in C-204 was TBP. Analyses of simulated wastes were also performed for the Waste Aging Studies Task; organics formed as a result of degradation were identified, and the original starting components were monitored quantitatively. Sample analysis is not routine and required considerable methods adaptation and optimization. Several techniques have been evaluated for directly analyzing chelator and chelator fragments in tank wastes: matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and liquid chromatography with ultraviolet detection using Cu complexation. Although not directly funded by the Tanks Safety Program, the success of these techniques have implications for both the Flammable Gas and Organic Tanks Safety Programs.

  9. The hazard analysis and critical control point system in food safety.

    PubMed

    Herrera, Anavella Gaitan

    2004-01-01

    The Hazard Analysis and Critical Control Point (HACCP) system is a preventive method of ensuring food safety. Its objectives are the identification of consumer safety hazards that can occur in the production line and the establishment of a control process to guarantee a safer product for the consumer; it is based on the identification of potential hazards to food safety and on measures aimed at preventing these hazards. HACCP is the system of choice in the management of food safety. The principles of HACCP are applicable to all phases of food production, including basic husbandry practices, food preparation and handling, food processing, food service, distribution systems, and consumer handling and use. The HACCP system is involved in every aspect of food safety production (according to the UN Food and Agriculture Organization [FAO] and the International Commission on Microbiological Specifications for Foods [ICMSF]). The most basic concept underlying the HACCP system is that of prevention rather than inspection. The control of processes and conditions comprises the critical control point (CCP) element. HACCP is simply a methodical, flexible, and systematic application of the appropriate science and technology for planning, controlling, and documenting the safe production of foods. The successful application of HACCP requires the full commitment and involvement of management and the workforce, using a multidisciplinary approach that should include, as appropriate, expertise in agronomy, veterinary health, microbiology, public health, food technology, environmental health, chemistry, engineering, and so on according to the particular situation. Application of the HACCP system is compatible with the implementation of total quality management (TQM) systems such as the ISO 9000 series. PMID:15156035

  10. Analysis on the saturation of refractive index modulation in fiber Bragg gratings (FBGs) written by partially coherent UV beams.

    PubMed

    Mahakud, Ramakanta; Prakash, Om; Nakhe, Shankar V; Dixit, Sudhir Kumar

    2012-04-20

    We present an analysis on the saturation of refractive index modulation of fiber Bragg gratings written in nonhydrogenated Ge-B co-doped single-mode photosensitive optical fiber by partially coherent pulsed UV beams. The UV beams of different spatial coherence properties were generated by second harmonic conversion of high repetition rate, high average power copper vapor laser (CVL) oscillators with different optical resonators. It is observed that for UV beams of higher spatial coherence, the fiber Bragg grating reflectivity growth was faster and saturation of refractive index modulation was higher. The experimental results are explained with the help of a physical model based on exponential decay of defect centers per unit volume on UV absorption in the fiber core. The subsequent increase in the refractive index was attributed to the structural modification and densification of the fiber core. PMID:22534886

  11. Bi-Directional Safety Analysis for Product-Line, Multi-Agent Systems Josh Dehlinger dehlinge@cs.iastate.edu (http://www.cs.iastate.edu/~dehlinge)

    E-print Network

    Lutz, Robyn R.

    1 Bi-Directional Safety Analysis for Product-Line, Multi-Agent Systems Josh Dehlinger dehlinge for product lines. We here propose the use of Bi-Directional Safety Analysis (BDSA) to aid in system produced contribute to the software's safety case for certification purposes. The product-line approach

  12. RESEARCH SAFETY RADIATION SAFETY

    E-print Network

    RESEARCH SAFETY RADIATION SAFETY ENVIRONMENTAL PROGRAMS HAZARDOUS MATERIALS CONTROLLED SUBSTANCES INTEGRATED WASTE MANAGEMENT LABORATORY SAFETY AUDITS & COMPLIANCE BIOSAFETY and ENVIRONMENTAL HEALTH EMERGENCY MANAGEMENT and MISSION CONTINUITY FIRE PREVENTION and LIFE SAFETY GENERAL SAFETY TRAINING

  13. Remote Safety Monitoring for Elderly Persons Based on Omni-Vision Analysis

    PubMed Central

    Xiang, Yun; Tang, Yi-ping; Ma, Bao-qing; Yan, Hang-chen; Jiang, Jun; Tian, Xu-yuan

    2015-01-01

    Remote monitoring service for elderly persons is important as the aged populations in most developed countries continue growing. To monitor the safety and health of the elderly population, we propose a novel omni-directional vision sensor based system, which can detect and track object motion, recognize human posture, and analyze human behavior automatically. In this work, we have made the following contributions: (1) we develop a remote safety monitoring system which can provide real-time and automatic health care for the elderly persons and (2) we design a novel motion history or energy images based algorithm for motion object tracking. Our system can accurately and efficiently collect, analyze, and transfer elderly activity information and provide health care in real-time. Experimental results show that our technique can improve the data analysis efficiency by 58.5% for object tracking. Moreover, for the human posture recognition application, the success rate can reach 98.6% on average. PMID:25978761

  14. Final safety analysis report for the Galileo Mission: Volume 2, Book 2: Accident model document: Appendices

    SciTech Connect

    Not Available

    1988-12-15

    This section of the Accident Model Document (AMD) presents the appendices which describe the various analyses that have been conducted for use in the Galileo Final Safety Analysis Report II, Volume II. Included in these appendices are the approaches, techniques, conditions and assumptions used in the development of the analytical models plus the detailed results of the analyses. Also included in these appendices are summaries of the accidents and their associated probabilities and environment models taken from the Shuttle Data Book (NSTS-08116), plus summaries of the several segments of the recent GPHS safety test program. The information presented in these appendices is used in Section 3.0 of the AMD to develop the Failure/Abort Sequence Trees (FASTs) and to determine the fuel releases (source terms) resulting from the potential Space Shuttle/IUS accidents throughout the missions.

  15. The statistical analysis of partially confounded covariates important to neural spiking

    PubMed Central

    Lepage, Kyle Q.; MacDonald, Christopher J.; Eichenbaum, Howard; Eden, Uri T.

    2014-01-01

    A method is presented capable of disambiguating the relative influence of statistical covariates upon neural spiking activity. The method, an extension of the generalized linear model (GLM) methodology introduced in Truccolo et al. (2005) to analyze neural spiking data, exploits projection operations motivated by a geometry present in the Fisher information of the GLM maximum likelihood parameter estimator. By exploiting these projections, neural activity can be divided into three categories. These three categories, neural activity due solely to a set of covariates of interest, neural activity due solely to a set of uninteresting, or nuisance, covariates, and neural activity that cannot be unequivocally assigned to either set of covariates, can be associated with physical variables such as time, position, head-direction and velocity. This association allows the analysis of neural activity that can, for example, be due solely to temporal influence, irrespective of other, identified, influences. The method is applied in simulation to a rat exploring a temporally modulated place field. A portion of the analysis reported in MacDonald et al. (2011), using the methodology described herein, is reproduced. This analysis demonstrates the temporal bridging of a delay period in a sequential memory task by firing activity of cells present in the rodent hippocampus that cannot be explained by rodent position, head direction or velocity. PMID:22281297

  16. Ares-I-X Vehicle Preliminary Range Safety Malfunction Turn Analysis

    NASA Technical Reports Server (NTRS)

    Beaty, James R.; Starr, Brett R.; Gowan, John W., Jr.

    2008-01-01

    Ares-I-X is the designation given to the flight test version of the Ares-I rocket (also known as the Crew Launch Vehicle - CLV) being developed by NASA. As part of the preliminary flight plan approval process for the test vehicle, a range safety malfunction turn analysis was performed to support the launch area risk assessment and vehicle destruct criteria development processes. Several vehicle failure scenarios were identified which could cause the vehicle trajectory to deviate from its normal flight path, and the effects of these failures were evaluated with an Ares-I-X 6 degrees-of-freedom (6-DOF) digital simulation, using the Program to Optimize Simulated Trajectories Version 2 (POST2) simulation framework. The Ares-I-X simulation analysis provides output files containing vehicle state information, which are used by other risk assessment and vehicle debris trajectory simulation tools to determine the risk to personnel and facilities in the vicinity of the launch area at Kennedy Space Center (KSC), and to develop the vehicle destruct criteria used by the flight test range safety officer. The simulation analysis approach used for this study is described, including descriptions of the failure modes which were considered and the underlying assumptions and ground rules of the study, and preliminary results are presented, determined by analysis of the trajectory deviation of the failure cases, compared with the expected vehicle trajectory.

  17. Safety and reliability analysis in a polyvinyl chloride batch process using dynamic simulator-case study: Loss of containment incident.

    PubMed

    Rizal, Datu; Tani, Shinichi; Nishiyama, Kimitoshi; Suzuki, Kazuhiko

    2006-10-11

    In this paper, a novel methodology in batch plant safety and reliability analysis is proposed using a dynamic simulator. A batch process involving several safety objects (e.g. sensors, controller, valves, etc.) is activated during the operational stage. The performance of the safety objects is evaluated by the dynamic simulation and a fault propagation model is generated. By using the fault propagation model, an improved fault tree analysis (FTA) method using switching signal mode (SSM) is developed for estimating the probability of failures. The timely dependent failures can be considered as unavailability of safety objects that can cause the accidents in a plant. Finally, the rank of safety object is formulated as performance index (PI) and can be estimated using the importance measures. PI shows the prioritization of safety objects that should be investigated for safety improvement program in the plants. The output of this method can be used for optimal policy in safety object improvement and maintenance. The dynamic simulator was constructed using Visual Modeler (VM, the plant simulator, developed by Omega Simulation Corp., Japan). A case study is focused on the loss of containment (LOC) incident at polyvinyl chloride (PVC) batch process which is consumed the hazardous material, vinyl chloride monomer (VCM). PMID:16777320

  18. Advanced neutron source reactor conceptual safety analysis report, three-element-core design: Chapter 15, accident analysis

    SciTech Connect

    Chen, N.C.J.; Wendel, M.W.; Yoder, G.L.; Harrington, R.M.

    1996-02-01

    In order to utilize reduced enrichment fuel, the three-element-core design for the Advanced Neutron Source has been proposed. The proposed core configuration consists of inner, middle, and outer elements, with the middle element offset axially beneath the inner and outer elements, which are axially aligned. The three-element-core RELAP5 model assumes that the reactor hardware is changed only within the core region, so that the loop piping, heat exchangers, and pumps remain as assumed for the two-element-core configuration. To assess the impact of changes in the core region configuration and the thermal-hydraulic steady-state conditions, the safety analysis has been updated. This report gives the safety margins for the loss-of-off-site power and pressure-boundary fault accidents based on the RELAP5 results. AU margins are greater for the three-element-core simulations than those calculated for the two-element core.

  19. Statistical evaluation and analysis of safety intervention in the determination of an effective resource allocation strategy

    Microsoft Academic Search

    Samuel A. Oyewole; Joel M. Haight; Andris Freivalds; David J. Cannon; Ling Rothrock

    2010-01-01

    This paper provides an analytical background for the development of an effective safety intervention program with the aim of minimizing incident rates. Safety intervention data were collected from the environmental health and safety department of an American-owned oil company in the Niger-Delta region of Nigeria. A safety model was developed to determine the safety intervention factors and interactions which minimize

  20. Safety climate and safety performance among construction workers in Hong Kong. The role of psychological strains as mediators.

    PubMed

    Siu, Oi-ling; Phillips, David R; Leung, Tat-wing

    2004-05-01

    This paper examines relations among safety climate (safety attitudes and communication), psychological strains (psychological distress and job satisfaction), and safety performance (self-reported accident rates and occupational injuries). A questionnaire was administered to construction workers from 27 construction sites in Hong Kong (N = 374, M = 366, F = 8, mean age =36.68 years). Data were collected by in-depth interviews and a survey from February to May 2000. A path analysis using the EQS-5 was employed to test the hypothesized model relating safety climate, safety performance, and psychological strains. The results provide partial support for the model, in that safety attitudes predict occupational injuries, and psychological distress predicts accident rates. Furthermore, psychological distress was found to be a mediator of the relationship between safety attitudes and accident rates. The implications of these results for psychological interventions in the construction industry are discussed. PMID:15003580

  1. Analysis of Blood Flow in a Partially Blocked Bifurcated Blood Vessel

    NASA Astrophysics Data System (ADS)

    Abdul-Razzak, Hayder; Elkassabgi, Yousri; Punati, Pavan K.; Nasser, Naseer

    2009-09-01

    Coronary artery disease is a major cause of death in the United States. It is the narrowing of the lumens of the coronary blood vessel by a gradual build-up of fatty material, atheroma, which leads to the heart muscle not receiving enough blood. This my ocardial ischemia can cause angina, a heart attack, heart failure as well as sudden cardiac death [9]. In this project a solid model of bifurcated blood vessel with an asymmetric stenosis is developed using GAMBIT and imported into FLUENT for analysis. In FLUENT, pressure and velocity distributions in the blood vessel are studied under different conditions, where the size and position of the blockage in the blood vessel are varied. The location and size of the blockage in the blood vessel are correlated with the pressures and velocities distributions. Results show that such correlation may be used to predict the size and location of the blockage.

  2. Information Extraction for System-Software Safety Analysis: Calendar Year 2007 Year-End Report

    NASA Technical Reports Server (NTRS)

    Malin, Jane T.

    2008-01-01

    This annual report describes work to integrate a set of tools to support early model-based analysis of failures and hazards due to system-software interactions. The tools perform and assist analysts in the following tasks: 1) extract model parts from text for architecture and safety/hazard models; 2) combine the parts with library information to develop the models for visualization and analysis; 3) perform graph analysis on the models to identify possible paths from hazard sources to vulnerable entities and functions, in nominal and anomalous system-software configurations; 4) perform discrete-time-based simulation on the models to investigate scenarios where these paths may play a role in failures and mishaps; and 5) identify resulting candidate scenarios for software integration testing. This paper describes new challenges in a NASA abort system case, and enhancements made to develop the integrated tool set.

  3. Quantitative safety assessment of computer based I and C systems via modular Markov analysis

    SciTech Connect

    Elks, C. R.; Yu, Y.; Johnson, B. W. [Univ. of Virginia, Dept. of Electrical and Computer Engineering, Charlottesville, VA 22903 (United States)

    2006-07-01

    This paper gives a brief overview of the methodology based on quantitative metrics for evaluating digital I and C system that has been under development at the Univ. of Virginia for a number years. Our quantitative assessment methodology is based on three well understood and extensively practiced disciplines in the dependability assessment field: (1) System level fault modeling and fault injection, (2) safety and coverage based dependability modeling methods, and (3) statistical estimation of model parameters used for safety predication. There are two contributions of this paper; the first contribution is related to incorporating design flaw information into homogenous Markov models when such data is available. The second is to introduce a Markov modeling method for managing the modeling complexities of large distributed I and C systems for the predication of safety and reliability. The method is called Modular Markov Chain analysis. This method allows Markov models of the system to be composed in a modular manner. In doing so, it address two important issues. (1) The models are more visually representative of the functional the system. (2) Important failure dependencies that naturally occur in complex systems are modeled accurately with our approach. (authors)

  4. Model-based safety analysis of human-robot interactions: the MIRAS walking assistance robot.

    PubMed

    Guiochet, Jérémie; Hoang, Quynh Anh Do; Kaaniche, Mohamed; Powell, David

    2013-06-01

    Robotic systems have to cope with various execution environments while guaranteeing safety, and in particular when they interact with humans during rehabilitation tasks. These systems are often critical since their failure can lead to human injury or even death. However, such systems are difficult to validate due to their high complexity and the fact that they operate within complex, variable and uncertain environments (including users), in which it is difficult to foresee all possible system behaviors. Because of the complexity of human-robot interactions, rigorous and systematic approaches are needed to assist the developers in the identification of significant threats and the implementation of efficient protection mechanisms, and in the elaboration of a sound argumentation to justify the level of safety that can be achieved by the system. For threat identification, we propose a method called HAZOP-UML based on a risk analysis technique adapted to system description models, focusing on human-robot interaction models. The output of this step is then injected in a structured safety argumentation using the GSN graphical notation. Those approaches have been successfully applied to the development of a walking assistant robot which is now in clinical validation. PMID:24187251

  5. Development of Non-LOCA Safety Analysis Methodology with RETRAN-3D and VIPRE-01/K

    SciTech Connect

    Kim, Yo-Han; Cheong, Ae-Ju; Yang, Chang-Keun [Korea Electric Power Research Institute (Korea, Republic of)

    2004-10-15

    Korea Electric Power Research Institute has launched a project to develop an in-house non-loss-of-coolant-accident analysis methodology to overcome the hardships caused by the narrow analytical scopes of existing methodologies. Prior to the development, some safety analysis codes were reviewed, and RETRAN-3D and VIPRE-01 were chosen as the base codes. The codes have been modified to improve the analytical capabilities required to analyze the nuclear power plants in Korea. The methodologies of the vendors and the Electric Power Research Institute have been reviewed, and some documents of foreign utilities have been used to compensate for the insufficiencies. For the next step, a draft methodology for pressurized water reactors has been developed and modified to apply to Westinghouse-type plants in Korea. To verify the feasibility of the methodology, some events of Yonggwang Units 1 and 2 have been analyzed from the standpoints of reactor coolant system pressure and the departure from nucleate boiling ratio. The results of the analyses show trends similar to those of the Final Safety Analysis Report.

  6. Safety Awards 

    E-print Network

    Unknown

    2011-08-17

    A RECONEENDED SAFETY PROGRAN FOR THE MABRY FOUNDRY AND NACHINE CONPANY AND IRON CASTINSS INCORPORATED OF BEAUNONT, TEXAS Edward Naz'shall Begnaud Appz'oved as to style and content by: n o osa ee n v sos') LfBRARY, A 4 M COLLEGE OF Texgt A... RECOMMENDED SAFETY PROGRAM FOR THE MABRY FOUNDRY AND MACHINE COMPANY AND IRON CASTINGS INCORPORATED OF BEAUMONT, TNXAS Edward Marshall Bsgnaud ll I Submitted to ths Graduate School of the Agricultuxal and. Mechanical College of Texas in Partial...

  7. Analysis of DNA methylation reveals a partial reprogramming of the Müller glia genome during retina regeneration

    PubMed Central

    Powell, Curtis; Grant, Ana R.; Cornblath, Eli; Goldman, Daniel

    2013-01-01

    Upon retinal injury, zebrafish Müller glia (MG) transition from a quiescent supportive cell to a progenitor cell (MGPC). This event is accompanied by the induction of key transcription and pluripotency factors. Because somatic cell reprogramming during induced pluripotent stem cell generation is accompanied by changes in DNA methylation, especially in pluripotency factor gene promoters, we were interested in determining whether DNA methylation changes also underlie MG reprogramming following retinal injury. Consistent with this idea, we found that genes encoding components of the DNA methylation/demethylation machinery were induced in MGPCs and that manipulating MGPC DNA methylation with 5-aza-2?-deoxycytidine altered their properties. A comprehensive analysis of the DNA methylation landscape as MG reprogram to MGPCs revealed that demethylation predominates at early times, whereas levels of de novo methylation increase at later times. We found that these changes in DNA methylation were largely independent of Apobec2 protein expression. A correlation between promoter DNA demethylation and injury-dependent gene induction was noted. In contrast to induced pluripotent stem cell formation, we found that pluripotency factor gene promoters were already hypomethylated in quiescent MG and remained unchanged in MGPCs. Interestingly, these pluripotency factor promoters were also found to be hypomethylated in mouse MG. Our data identify a dynamic DNA methylation landscape as zebrafish MG transition to an MGPC and suggest that DNA methylation changes will complement other regulatory mechanisms to ensure gene expression programs controlling MG reprogramming are appropriately activated during retina regeneration. PMID:24248357

  8. Frequency agile laser safety & hazard analysis for the Sandia Remote Sensing System LIDAR.

    SciTech Connect

    Augustoni, Arnold L.

    2009-05-01

    A laser safety and hazard analysis was performed for the Raytheon Frequency Agile Laser (FAL) to be used with the Sandia Remote Sensing System (SRSS) B-70 Trailer based on the 2007 version of the American National Standards Institute's (ANSI) Standard 136.1, for Safe Use of Lasers and the 2005 version of the ANSI Standard Z136.6, for Safe Use of Lasers Outdoors. The B-70 SRSS LIDAR system is a portable platform, which is used to perform laser interaction experiments and tests at various national test sites.

  9. Investigating the Use of 3-D Deterministic Transport for Core Safety Analysis

    SciTech Connect

    H. D. Gougar; D. Scott

    2004-04-01

    An LDRD (Laboratory Directed Research and Development) project is underway at the Idaho National Laboratory (INL) to demonstrate the feasibility of using a three-dimensional multi-group deterministic neutron transport code (Attila®) to perform global (core-wide) criticality, flux and depletion calculations for safety analysis of the Advanced Test Reactor (ATR). This paper discusses the ATR, model development, capabilities of Attila, generation of the cross-section libraries, comparisons to experimental results for Advanced Fuel Cycle (AFC) concepts, and future work planned with Attila.

  10. Breach and safety analysis of spills over water from large liquefied natural gas carriers.

    SciTech Connect

    Hightower, Marion Michael; Luketa-Hanlin, Anay Josephine; Attaway, Stephen W.

    2008-05-01

    In 2004, at the request of the Department of Energy, Sandia National Laboratories (Sandia) prepared a report, ''Guidance on the Risk and Safety Analysis of Large Liquefied Natural Gas (LNG) Spills Over Water''. That report provided framework for assessing hazards and identifying approaches to minimize the consequences to people and property from an LNG spill over water. The report also presented the general scale of possible hazards from a spill from 125,000 m3 o 150,000 m3 class LNG carriers, at the time the most common LNG carrier capacity.

  11. Workplace safety: a meta-analysis of the roles of person and situation factors.

    PubMed

    Christian, Michael S; Bradley, Jill C; Wallace, J Craig; Burke, Michael J

    2009-09-01

    Recent conceptual and methodological advances in behavioral safety research afford an opportunity to integrate past and recent research findings. Building on theoretical models of worker performance and work climate, this study quantitatively integrates the safety literature by meta-analytically examining person- and situation-based antecedents of safety performance behaviors and safety outcomes (i.e., accidents and injuries). As anticipated, safety knowledge and safety motivation were most strongly related to safety performance behaviors, closely followed by psychological safety climate and group safety climate. With regard to accidents and injuries, however, group safety climate had the strongest association. In addition, tests of a meta-analytic path model provided support for the theoretical model that guided this overall investigation. The implications of these findings for advancing the study and management of workplace safety are discussed. PMID:19702360

  12. Understanding waste phenomenology to reduce the amount of sampling and analysis required to resolve Hanford waste tank safety issues

    SciTech Connect

    Meacham, J.E.; Babad, H.

    1996-02-01

    Safety issues associated with Hanford Site waste tanks arose because of inadequate safety analyses and high levels of uncertainty over the release of radioactivity resulting from condensed phase exothermic chemical reactions (organic solvent fires, organic complexant-nitrate reactions, and ferrocyanide-nitrate reactions). The approach to resolving the Organic Complexant, Organic Solvent, and Ferrocyanide safety issues has changed considerably since 1990. The approach formerly utilized core sampling and extensive analysis of the samples with the expectation the data would provide insight into the hazard. This resulted in high costs and the generation of a large amount of data that was of limited value in resolving the safety issues. The new approach relies on an understanding of the hazard phenomenology to focus sampling and analysis on those analytes that are key to ensuring safe storage of the waste.

  13. Safety Analysis of Small Break Loss of Coolant Accident for 1200 MWe Simplified Boiling Water Reactor (SBWR-1200 BDLB)

    SciTech Connect

    Xu, Y.; Revankar, S.T.; Ishii, M. [School of Nuclear Engineering, Purdue University, West Lafayette, IN 47907-1290 (United States)

    2002-07-01

    The objective of this research is to assess the performance of the safety systems during small break loss of coolant accident (SBLOCA) transient in the full size SBWR. RELAP5/MOD3 was used to simulate the blow-down and long-term cooling responses of the various safety systems during the accident transient. An integral test for long-term cooling under low pressure was conducted in a scaled facility with the initial conditions given by the code simulation. The code applicability and the facility scalability were evaluated by the comparison between the test data and the code simulations. The scaling analysis has been done by the comparison of the prototype code predictions and the scaled-up test data with the proper scaling multiplications and time shifting. The good agreement between the major safety parameters has shown the applicability of the RELAP5/MOD3 code and the scalability of the facility for SBWR-1200 safety analysis applications. (authors)

  14. A novel exploratory chemometric approach to environmental monitorring by combining block clustering with Partial Least Square (PLS) analysis

    PubMed Central

    2013-01-01

    Background Given the serious threats posed to terrestrial ecosystems by industrial contamination, environmental monitoring is a standard procedure used for assessing the current status of an environment or trends in environmental parameters. Measurement of metal concentrations at different trophic levels followed by their statistical analysis using exploratory multivariate methods can provide meaningful information on the status of environmental quality. In this context, the present paper proposes a novel chemometric approach to standard statistical methods by combining the Block clustering with Partial least square (PLS) analysis to investigate the accumulation patterns of metals in anthropized terrestrial ecosystems. The present study focused on copper, zinc, manganese, iron, cobalt, cadmium, nickel, and lead transfer along a soil-plant-snai food chain, and the hepatopancreas of the Roman snail (Helix pomatia) was used as a biological end-point of metal accumulation. Results Block clustering deliniates between the areas exposed to industrial and vehicular contamination. The toxic metals have similar distributions in the nettle leaves and snail hepatopancreas. PLS analysis showed that (1) zinc and copper concentrations at the lower trophic levels are the most important latent factors that contribute to metal accumulation in land snails; (2) cadmium and lead are the main determinants of pollution pattern in areas exposed to industrial contamination; (3) at the sites located near roads lead is the most threatfull metal for terrestrial ecosystems. Conclusion There were three major benefits by applying block clustering with PLS for processing the obtained data: firstly, it helped in grouping sites depending on the type of contamination. Secondly, it was valuable for identifying the latent factors that contribute the most to metal accumulation in land snails. Finally, it optimized the number and type of data that are best for monitoring the status of metallic contamination in terrestrial ecosystems exposed to different kinds of anthropic polution. PMID:23987502

  15. Analysis and comparison of five contractor safety and health manuals (EG and G, SR II, ORNL, Ashland, and MLGW)

    SciTech Connect

    Crowder, C.; Hurley, T.

    1981-03-01

    An analysis is presented of five safety and health contractor manuals against the requirements of the FE OSH Manual (FE 5480.1), and a breakdown in chart form of how the manuals compare to each other is given. It is pointed out that the manuals are inadequate, but that site visits will be necessary to determine the actual comprehensiveness of the facilities' safety and health programs.

  16. Safety analysis of the 1000 lb/day coal-liquefaction PDU

    SciTech Connect

    Hulburt, D.A.

    1981-05-01

    The objective of the program reported herein was to provide a Safety Analysis of the 1000 lb/day PDU located in Building 83 at the Pittsburgh Energy Technology Center. Risks to personnel from potential process hazards are largely controlled by installation of a major portion of the unit within a hot cell. This segregates and isolates personnel from a majority of potential equipment rupture and fire/explosion hazards. Equipment within the cell is subject to potential risks associated with overpressurization or excessively high temperature, and fire/explosion due to ignition of leaking flammable gas (i.e. H/sub 2/). There are some existing safeguards designed to protect against overpressure or high temperature. Additional safeguards are offered to minimize these risks. The hot cell is provided with general dilution ventilation and hydrogen monitoring. However, confinement effects and potential ignition sources are such that avoidance of formation and ignition of flammable mixtures cannot be assured. Potential health hazards relate to contact with coal-derived liquids or inhalation of irritant or toxic gases, vapors, or dusts, associated with slurry preparation, sampling, draw down of catch-pots, or cleaning of centrifuge bowls. No particularly serious workplace safety hazards were identified, and environmental concerns are largely limited by the relatively low throughput for the unit. A number of Category I hazards with Remote likelihood, and Category II hazards with May Occur likelihood, were identified. Recommendations were developed for these hazards. Implementation of these recommendations will materially reduce the overall risk level of the operation. The Safety Analysis was based on a site visit, process flow diagrams, material balance, equipment data, and operating procedures provided to Hercules, or as represented to Hercules, by the Pittsburgh Energy Technology Center. A detailed listing of the data and information package is documented in Appendix A.

  17. Safety analysis, 200 Area, Savannah River Plant H-Canyon operations. Supplement 5

    SciTech Connect

    Beary, M.M.; Collier, C.D.; Fairobent, L.A.; Graham, R.F.; Mason, C.L.; McDuffee, W.T.; Owen, T.L.; Walker, D.H. [Science Applications International Corp., San Diego, CA (United States)

    1986-02-01

    The H-Canyon facility is located in the 200 Separations Area and uses the HM process to separate uranium, neptunium, plutonium, and fission products. Irradiated uranium fuels containing {sup 235}U at enrichments from 1.1% to 94% are processed and recovered, along with neptunium and plutonium isotopes. This Safety Analysis Report (SAR) documents an analysis of the H-Canyon operations and is an update to a section of a previous SAR. This SAR documents an analysis of the H-Canyon and is one of a series of documents for the Separations Area as specified in the Savannah River Implementation Plans. A substantial amount of the information supporting the Conclusions of this SAR is found in the Systems Analysis. Some H-Canyon equipment has been updated during the time between the Systems Analysis and this SAR and a complete description of this equipment is included in this report. The primary purpose of the analysis was to demonstrate that the H-Carbon can be operated without due risk to onsite or offsite populations and to the environment. In this report, risk is defined an the expected frequency of an accident, multiplied by the resulting radiological consequence in person-rem. The units of risk for radiological does are person-rem/year. Maximum individual exposure values have also been calculated and reported.

  18. Safety analysis, 200 Area, Savannah River Plant H-Canyon operations

    SciTech Connect

    Beary, M.M.; Collier, C.D.; Fairobent, L.A.; Graham, R.F.; Mason, C.L.; McDuffee, W.T.; Owen, T.L.; Walker, D.H. (Science Applications International Corp., San Diego, CA (United States))

    1986-02-01

    The H-Canyon facility is located in the 200 Separations Area and uses the HM process to separate uranium, neptunium, plutonium, and fission products. Irradiated uranium fuels containing [sup 235]U at enrichments from 1.1% to 94% are processed and recovered, along with neptunium and plutonium isotopes. This Safety Analysis Report (SAR) documents an analysis of the H-Canyon operations and is an update to a section of a previous SAR. This SAR documents an analysis of the H-Canyon and is one of a series of documents for the Separations Area as specified in the Savannah River Implementation Plans. A substantial amount of the information supporting the Conclusions of this SAR is found in the Systems Analysis. Some H-Canyon equipment has been updated during the time between the Systems Analysis and this SAR and a complete description of this equipment is included in this report. The primary purpose of the analysis was to demonstrate that the H-Carbon can be operated without due risk to onsite or offsite populations and to the environment. In this report, risk is defined an the expected frequency of an accident, multiplied by the resulting radiological consequence in person-rem. The units of risk for radiological does are person-rem/year. Maximum individual exposure values have also been calculated and reported.

  19. Analysis of environment, safety, and health (ES&H) management systems for Department of Energy (DOE) Defense Programs (DP) facilities

    Microsoft Academic Search

    Neglia

    1998-01-01

    The purpose of this paper is to provide a summary analysis and comparison of various environment, safety, and health (ES&H) management systems required of, or suggested for use by, the Departrnent of Energy Defense Programs` sites. The summary analysis is provided by means of a comparison matrix, a set of Vean diagrams that highlights the focus of the systems, and

  20. Task analysis for the investigation of human error in safety- critical software design: a convergent methods approach

    Microsoft Academic Search

    N. M. SHRYANE; S. J. W ESTERM; C. M. C RAWSHAW; G. R. J. H OCK; J. SAUER

    1998-01-01

    An investigation was conducted into sources of error within a safety-critical software design task. A number of convergent methods of task- and error-analysis were systematically applied: hierarchical task analysis (HTA), error log audit, error observation, work sample and laboratory experiment. HTA, which provided the framework for the deployment of subsequent methods, revealed possible weaknesses in the areas of task automation

  1. The efficacy and safety of rituximab in treating childhood refractory nephrotic syndrome: A meta-analysis

    PubMed Central

    Zhao, Zhihong; Liao, Guixiang; Li, Yongqiang; Zhou, Shulu; Zou, Hequn

    2015-01-01

    Rituximab is considered to be a promising drug for treating childhood refractory nephrotic syndrome. However, the efficacy and safety of rituximab in treating childhood refractory nephrotic syndrome remain inconclusive. This meta-analysis aimed to investigate the efficacy and safety of rituximab treatment compared with other immunosuppressive agents in children with refractory nephrotic syndrome. Three randomized controlled trials and two comparative control studies were included in our analysis. The included studies were of moderately high quality. Compared with other immunotherapies, rituximab therapy significantly improved relapse-free survival (hazard ratio = 0.49, 95% confidence interval [CI], 0.26–0.92, P = 0.03). Rituximab also achieved a higher rate of complete remission (risk ratio,1.62; 95% CI, 0.92 to 2.84, P = 0.09) and reduced the occurrence of proteinuria (mean difference = ?0.25, 95% CI = ?0.29 to ?0.21, P < 0.00001); however, a more targeted rituximab treatment did not significantly increase serum albumin levels and did not significantly reduce adverse events. Rituximab might be a promising treatment for childhood refractory nephrotic syndrome; however, the long-term effects and cost-effectiveness of rituximab treatment were not fully assessed, and there were limited studies that evaluated the clinical benefits of a concurrent infusion of rituximab plus a steroid compared with an infusion of rituximab only. Additional studies are required to address these issues. PMID:25645999

  2. Safety Products, Inc.: A case in financial analysis of a failing company

    Microsoft Academic Search

    James P. Jennings; Eleanor G. Henry

    2008-01-01

    Safety Products, Inc. was a small, private corporation that manufactured acrylic sheet plastic. After a massive fire, the company filed a claim against its business interruption insurance for lost income. The policy covered profits that would have been earned, based on Safety’s financial records, had the disaster not occurred. The insurance company denied the claim on the grounds that Safety

  3. Simulation for Prediction of Entry Article Demise (SPEAD): An Analysis Tool for Spacecraft Safety Analysis and Ascent/Reentry Risk Assessment

    NASA Technical Reports Server (NTRS)

    Ling, Lisa

    2014-01-01

    For the purpose of performing safety analysis and risk assessment for a potential off-nominal atmospheric reentry resulting in vehicle breakup, a synthesis of trajectory propagation coupled with thermal analysis and the evaluation of node failure is required to predict the sequence of events, the timeline, and the progressive demise of spacecraft components. To provide this capability, the Simulation for Prediction of Entry Article Demise (SPEAD) analysis tool was developed. The software and methodology have been validated against actual flights, telemetry data, and validated software, and safety/risk analyses were performed for various programs using SPEAD. This report discusses the capabilities, modeling, validation, and application of the SPEAD analysis tool.

  4. Laser safety and hazard analysis for the temperature stabilized BSLT ARES laser system.

    SciTech Connect

    Augustoni, Arnold L.

    2003-08-01

    A laser safety and hazard analysis was performed for the temperature stabilized Big Sky Laser Technology (BSLT) laser central to the ARES system based on the 2000 version of the American National Standards Institute's (ANSI) Standard Z136.1, for Safe Use of Lasers and the 2000 version of the ANSI Standard Z136.6, for Safe Use of Lasers Outdoors. As a result of temperature stabilization of the BSLT laser the operating parameters of the laser had changed requiring a hazard analysis based on the new operating conditions. The ARES laser system is a Van/Truck based mobile platform, which is used to perform laser interaction experiments and tests at various national test sites.

  5. Fault analysis of the DIII-D neutral beam safety interlock system

    SciTech Connect

    Phillips, J.C.; Colleraine, A.P.; Haskovec, J.S.; Hong, R.; Kim, J.; Sleaford, B.W.; Tooker, J.F.; Wight, J.J.

    1987-10-01

    The DIII-D neutral beam injection systems (NBIS) at GA Technologies rely on a substantial array of control and instrumentation for routine operation. Functions include shot sequencing, power supply control, vacuum control, and valve control, long with interlocks for safequarding personnel and equipment. Failures resulting from improper operation of the neutral beamlines, their power supplies, and supporting services have the potential to cause extensive damage to personnel, equipment, and beamline components, as well as delay of the experimental schedule. This paper will address only equipment and component failures. Intelligence and control are distributed over dissimilar types of equipment in separate locations. An analysis has been made of the possible failure modes of the subsystems and the interlocking of systems and operations. This has helped us to improve the design of the safety interlock system and to minimize the risk to the NBIS project. The analysis technique will be presented and possible outcomes of typical failure modes explored. 5 refs., 2 figs.

  6. Probabilistic risk analysis toward cost-effective 3S (safety, safeguards, security) implementation

    SciTech Connect

    Suzuki, Mitsutoshi; Mochiji, Toshiro [Department of Science and Technology for Nuclear Material Management, Japan Atomic Energy Agency, 2-4 Shirane, Shirakata, Tokai-mura, Naka-gun, Ibaraki 319-1193 (Japan)

    2014-09-30

    Probabilistic Risk Analysis (PRA) has been introduced for several decades in safety and nuclear advanced countries have already used this methodology in their own regulatory systems. However, PRA has not been developed in safeguards and security so far because of inherent difficulties in intentional and malicious acts. In this paper, probabilistic proliferation and risk analysis based on random process is applied to hypothetical reprocessing process and physical protection system in nuclear reactor with the Markov model that was originally developed by the Proliferation Resistance and Physical Protection Working Group (PRPPWG) in Generation IV International Framework (GIF). Through the challenge to quantify the security risk with a frequency in this model, integrated risk notion among 3S to pursue the cost-effective installation of those countermeasures is discussed in a heroic manner.

  7. Navier-Stokes flow field analysis of compressible flow in a high pressure safety relief valve

    NASA Technical Reports Server (NTRS)

    Vu, Bruce; Wang, Ten-See; Shih, Ming-Hsin; Soni, Bharat

    1993-01-01

    The objective of this study is to investigate the complex three-dimensional flowfield of an oxygen safety pressure relieve valve during an incident, with a computational fluid dynamic (CFD) analysis. Specifically, the analysis will provide a flow pattern that would lead to the expansion of the eventual erosion pattern of the hardware, so as to combine it with other findings to piece together a most likely scenario for the investigation. The CFD model is a pressure based solver. An adaptive upwind difference scheme is employed for the spatial discretization, and a predictor, multiple corrector method is used for the velocity-pressure coupling. The computational result indicated vortices formation near the opening of the valve which matched the erosion pattern of the damaged hardware.

  8. An Analysis of Cooperative Coevolutionary Algorithms A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at

    E-print Network

    Wiegand, R. Paul

    An Analysis of Cooperative Coevolutionary Algorithms A dissertation submitted in partial Services. They do a huge and irreplaceable service for those of us in deep study, and probably cannot to be among the many who say that life is an adventure of learning and for every question answered

  9. Modelling of cycle to cycle behaviour for partial discharge events within a spherical cavity in a solid dielectric material by using Finite Element Analysis

    Microsoft Academic Search

    Hazlee A. Illias; George Chen; Paul L. Lewin

    2010-01-01

    A partial discharge (PD) analysis method that can be used to observe cycle to cycle behaviour of PD activity is to plot PD charge magnitude and voltage of PD occurrence against phase angle for certain numbers of cycles of the applied voltage. The advantage of this method is it gives a better picture of PD activity behaviour in terms of

  10. Food Safety Attitudes in College Students: A Structural Equation Modeling Analysis of a Conceptual Model

    PubMed Central

    Booth, Rachelle; Hernandez, Magaly; Baker, Erica L.; Grajales, Tevni; Pribis, Peter

    2013-01-01

    College students are one of the most at-risk population groups for food poisoning, due to risky food safety behaviors. Using the Likert Scale, undergraduate students were asked to participate in a Food Safety Survey which was completed by 499 students ages 18–25. Data was analyzed using SPSS and AMOS statistical software. Four conceptual definitions regarding food safety were defined as: general food safety, bacterial food safety, produce food safety, and politics associated with food safety. Knowledge seems to be an important factor in shaping students attitudes regarding general and bacterial safety. Ethnicity plays a role in how people view the politics of food safety, and the safety of organic foods. PMID:23364131

  11. Planning, Encoding, and Overcoming Conflict in Partial Occlusion Drawing: A Neo-Piagetian Model and an Experimental Analysis.

    ERIC Educational Resources Information Center

    Morra, Sergio; And Others

    1996-01-01

    Presents a theoretical model of partial occlusion drawing, along with three experiments. Experiment one studied whether planning or scanning is involved in partial occlusion drawing, and the second explored whether group-encoding of similar objects creates a drawing problem. Experiment three tested predictions derived on the conjoint effects of…

  12. A new mutation of the androgen receptor, P817A, causing partial androgen insensitivity syndrome: in vitro and structural analysis.

    PubMed

    Lumbroso, S; Wagschal, A; Bourguet, W; Georget, V; Mazen, I; Servant, N; Audran, F; Sultan, C; Auzou, G

    2004-06-01

    Androgen insensitivity syndrome (AIS) is an X-linked disease caused by mutations in the androgen receptor (AR) resulting in various degrees of defective masculinization in 46,XY individuals. In the present study, we describe a novel mutation in exon 7 of the AR gene in an Egyptian patient with partial AIS (PAIS). Sequencing analysis of the AR gene revealed a novel missense mutation, P817A, within the ligand-binding domain (LBD). This is the first report of a mutation within the short amino acid motif (codons 815-817) of the beta-strand lying between helices H8 and H9 of the AR LBD. The functional defects of the mutated protein were characterized by in vitro study and included significantly decreased ligand-binding affinity and impaired transactivation potential. Limited proteolysis assays performed with the wild-type and mutant AR receptors incubated with the synthetic agonist R1881 revealed that the P817A mutation resulted in a reduced stabilization of the AR active conformation. Structural analyses showed that this mutation is likely to perturb the beta-sheet interaction between residues 815-817 and 911-913. This structural alteration destabilizes the position of the C-terminal extension, which contains residues critical for androgen function. PMID:15171708

  13. A new strategy to prevent over-fitting in partial least squares models based on model population analysis.

    PubMed

    Deng, Bai-Chuan; Yun, Yong-Huan; Liang, Yi-Zeng; Cao, Dong-Sheng; Xu, Qing-Song; Yi, Lun-Zhao; Huang, Xin

    2015-06-23

    Partial least squares (PLS) is one of the most widely used methods for chemical modeling. However, like many other parameter tunable methods, it has strong tendency of over-fitting. Thus, a crucial step in PLS model building is to select the optimal number of latent variables (nLVs). Cross-validation (CV) is the most popular method for PLS model selection because it selects a model from the perspective of prediction ability. However, a clear minimum of prediction errors may not be obtained in CV which makes the model selection difficult. To solve the problem, we proposed a new strategy for PLS model selection which combines the cross-validated coefficient of determination (Qcv(2)) and model stability (S). S is defined as the stability of PLS regression vectors which is obtained using model population analysis (MPA). The results show that, when a clear maximum of Qcv(2) is not obtained, S can provide additional information of over-fitting and it helps in finding the optimal nLVs. Compared with other regression vector based indictors such as the Euclidean 2-norm (B2), the Durbin Watson statistic (DW) and the jaggedness (J), S is more sensitive to over-fitting. The model selected by our method has both good prediction ability and stability. PMID:26092335

  14. Analysis of Preventive Interventions for Malaria: Exploring Partial and Complete Protection and Total and Primary Intervention Effects.

    PubMed

    Cairns, Matthew; Cheung, Yin Bun; Xu, Ying; Asante, Kwaku Poku; Owusu-Agyei, Seth; Diallo, Diadier; Konate, Amadou T; Dicko, Alassane; Chandramohan, Daniel; Greenwood, Brian; Milligan, Paul

    2015-06-15

    Event dependence, the phenomenon in which future risk depends on past disease history, is not commonly accounted for in the statistical models used by malaria researchers. However, recently developed methods for the analysis of repeated events allow this to be done, while also accounting for heterogeneity in risk and nonsusceptible subgroups. Accounting for event dependence allows separation of the primary effect of an intervention from its total effect, which is composed of its primary effect on risk of disease and its secondary effect mediated by event dependence. To illustrate these methods and show the insights they can provide, we have reanalyzed 2 trials of seasonal malaria chemoprevention (SMC) in Boussé, Burkina Faso, and Kati, Mali, in 2008-2009, as well as a trial of intermittent preventive treatment of malaria in infants in Navrongo, Ghana, in 2000-2004. SMC completely protects a large fraction of recipients, while intermittent preventive treatment in infants provides modest partial protection, consistent with the rationale of these 2 different chemopreventive approaches. SMC has a primary effect that is substantially greater than the total effect previously estimated by trials, with the lower total effect mediated by negative event dependence. These methods contribute to an understanding of the mechanisms of protection from these interventions and could improve understanding of other tools to control malaria, including vaccines. PMID:26022663

  15. Analysis of Preventive Interventions for Malaria: Exploring Partial and Complete Protection and Total and Primary Intervention Effects

    PubMed Central

    Cairns, Matthew; Cheung, Yin Bun; Xu, Ying; Asante, Kwaku Poku; Owusu-Agyei, Seth; Diallo, Diadier; Konate, Amadou T.; Dicko, Alassane; Chandramohan, Daniel; Greenwood, Brian; Milligan, Paul

    2015-01-01

    Event dependence, the phenomenon in which future risk depends on past disease history, is not commonly accounted for in the statistical models used by malaria researchers. However, recently developed methods for the analysis of repeated events allow this to be done, while also accounting for heterogeneity in risk and nonsusceptible subgroups. Accounting for event dependence allows separation of the primary effect of an intervention from its total effect, which is composed of its primary effect on risk of disease and its secondary effect mediated by event dependence. To illustrate these methods and show the insights they can provide, we have reanalyzed 2 trials of seasonal malaria chemoprevention (SMC) in Boussé, Burkina Faso, and Kati, Mali, in 2008–2009, as well as a trial of intermittent preventive treatment of malaria in infants in Navrongo, Ghana, in 2000–2004. SMC completely protects a large fraction of recipients, while intermittent preventive treatment in infants provides modest partial protection, consistent with the rationale of these 2 different chemopreventive approaches. SMC has a primary effect that is substantially greater than the total effect previously estimated by trials, with the lower total effect mediated by negative event dependence. These methods contribute to an understanding of the mechanisms of protection from these interventions and could improve understanding of other tools to control malaria, including vaccines. PMID:26022663

  16. Comparative artificial neural network and partial least squares models for analysis of Metronidazole, Diloxanide, Spiramycin and Cliquinol in pharmaceutical preparations

    NASA Astrophysics Data System (ADS)

    Elkhoudary, Mahmoud M.; Abdel Salam, Randa A.; Hadad, Ghada M.

    2014-09-01

    Metronidazole (MNZ) is a widely used antibacterial and amoebicide drug. Therefore, it is important to develop a rapid and specific analytical method for the determination of MNZ in mixture with Spiramycin (SPY), Diloxanide (DIX) and Cliquinol (CLQ) in pharmaceutical preparations. This work describes simple, sensitive and reliable six multivariate calibration methods, namely linear and nonlinear artificial neural networks preceded by genetic algorithm (GA-ANN) and principle component analysis (PCA-ANN) as well as partial least squares (PLS) either alone or preceded by genetic algorithm (GA-PLS) for UV spectrophotometric determination of MNZ, SPY, DIX and CLQ in pharmaceutical preparations with no interference of pharmaceutical additives. The results manifest the problem of nonlinearity and how models like ANN can handle it. Analytical performance of these methods was statistically validated with respect to linearity, accuracy, precision and specificity. The developed methods indicate the ability of the previously mentioned multivariate calibration models to handle and solve UV spectra of the four components’ mixtures using easy and widely used UV spectrophotometer.

  17. Limiting the sedimentation coefficient for sedimentation velocity data analysis: partial boundary modeling and g(s) approaches revisited.

    PubMed

    Philo, John S

    2011-05-15

    Brown and coworkers (Eur. Biophys. J. 38 (2009) 1079-1099) introduced partial boundary modeling (PBM) to simplify sedimentation velocity data analysis by excluding species outside the range of interest (e.g., aggregates, impurities) via restricting the sedimentation coefficient range being fitted. They strongly criticized the alternate approach of fitting g(s) distributions using similar range limits, arguing that (i) it produces "nonoptimal fits in the original data space" and (ii) the g(s) data transformations lead to gross underestimates of the parameter confidence intervals. It is shown here that neither of those criticisms is valid. These two approaches are not truly fitting the same data or in equivalent ways; thus, they should not actually give the same best-fit parameters. The confidence limits for g(s) fits derived using F statistics, bootstrap, or a new Monte Carlo algorithm are in good agreement and show no evidence for significant statistical distortion. Here 15 g(s) measurements on monoclonal antibody samples gave monomer mass estimates with experimental standard deviations of less than 1%, close to the confidence limit estimates. Tests on both real and simulated data help to clarify the strengths and drawbacks of both approaches. New algorithms for computing g(s) and a scan-differencing approach for PBM are introduced. PMID:21284932

  18. Comparative artificial neural network and partial least squares models for analysis of Metronidazole, Diloxanide, Spiramycin and Cliquinol in pharmaceutical preparations.

    PubMed

    Elkhoudary, Mahmoud M; Abdel Salam, Randa A; Hadad, Ghada M

    2014-09-15

    Metronidazole (MNZ) is a widely used antibacterial and amoebicide drug. Therefore, it is important to develop a rapid and specific analytical method for the determination of MNZ in mixture with Spiramycin (SPY), Diloxanide (DIX) and Cliquinol (CLQ) in pharmaceutical preparations. This work describes simple, sensitive and reliable six multivariate calibration methods, namely linear and nonlinear artificial neural networks preceded by genetic algorithm (GA-ANN) and principle component analysis (PCA-ANN) as well as partial least squares (PLS) either alone or preceded by genetic algorithm (GA-PLS) for UV spectrophotometric determination of MNZ, SPY, DIX and CLQ in pharmaceutical preparations with no interference of pharmaceutical additives. The results manifest the problem of nonlinearity and how models like ANN can handle it. Analytical performance of these methods was statistically validated with respect to linearity, accuracy, precision and specificity. The developed methods indicate the ability of the previously mentioned multivariate calibration models to handle and solve UV spectra of the four components' mixtures using easy and widely used UV spectrophotometer. PMID:24792195

  19. Photoelastic Analysis of Fixed Partial Prosthesis Crown Height and Implant Length on Distribution of Stress in Two Dental Implant Systems

    PubMed Central

    Figueirêdo, Evandro Portela; Sigua-Rodriguez, Eder Alberto; Pimentel, Marcele Jardim; Nóbilo, Mauro Antônio de Arruda; de Albergaria-Barbosa, José Ricardo

    2014-01-01

    The aim of this study was to evaluate by photoelastic analysis stress distribution on short and long implants of two dental implant systems with 2-unit implant-supported fixed partial prostheses of 8?mm and 13?mm heights. Sixteen photoelastic models were divided into 4 groups: I: long implant (5 × 11?mm) (Neodent), II: long implant (5 × 11?mm) (Bicon), III: short implant (5 × 6?mm) (Neodent), and IV: short implants (5 × 6?mm) (Bicon). The models were positioned in a circular polariscope associated with a cell load and static axial (0.5?Kgf) and nonaxial load (15°, 0.5?Kgf) were applied to each group for both prosthetic crown heights. Three-way ANOVA was used to compare the factors implant length, crown height, and implant system (? = 0.05). The results showed that implant length was a statistically significant factor for both axial and nonaxial loading. The 13?mm prosthetic crown did not result in statistically significant differences in stress distribution between the implant systems and implant lengths studied, regardless of load type (P > 0.05). It can be concluded that short implants showed higher stress levels than long implants. Implant system and length was not relevant factors when prosthetic crown height were increased. PMID:25374603

  20. Exploration of High-Dimensional Scalar Function for Nuclear Reactor Safety Analysis and Visualization

    SciTech Connect

    Dan Maljovec; Bei Wang; Valerio Pascucci; Peer-Timo Bremer; Michael Pernice; Robert Nourgaliev

    2013-05-01

    The next generation of methodologies for nuclear reactor Probabilistic Risk Assessment (PRA) explicitly accounts for the time element in modeling the probabilistic system evolution and uses numerical simulation tools to account for possible dependencies between failure events. The Monte-Carlo (MC) and the Dynamic Event Tree (DET) approaches belong to this new class of dynamic PRA methodologies. A challenge of dynamic PRA algorithms is the large amount of data they produce which may be difficult to visualize and analyze in order to extract useful information. We present a software tool that is designed to address these goals. We model a large-scale nuclear simulation dataset as a high-dimensional scalar function defined over a discrete sample of the domain. First, we provide structural analysis of such a function at multiple scales and provide insight into the relationship between the input parameters and the output. Second, we enable exploratory analysis for users, where we help the users to differentiate features from noise through multi-scale analysis on an interactive platform, based on domain knowledge and data characterization. Our analysis is performed by exploiting the topological and geometric properties of the domain, building statistical models based on its topological segmentations and providing interactive visual interfaces to facilitate such explorations. We provide a user’s guide to our software tool by highlighting its analysis and visualization capabilities, along with a use case involving dataset from a nuclear reactor safety simulation.