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Sample records for peter van den

  1. Rater Biases in Genetically Informative Research Designs: Comment on Bartels, Boomsma, Hudziak, van Beijsterveldt, and van den Oord (2007)

    ERIC Educational Resources Information Center

    Hoyt, William T.

    2007-01-01

    Rater biases are of interest to behavior genetic researchers, who often use ratings data as a basis for studying heritability. Inclusion of multiple raters for each sibling pair (M. Bartels, D. I. Boomsma, J. J. Hudziak, T. C. E. M. van Beijsterveldt, & E. J. C. G. van den Oord, 2007) is a promising strategy for controlling bias variance and may…

  2. The homeopathy of kin selection: an evaluation of Van den Berghe's sociobiological approach to ethnic nepotism.

    PubMed

    Brigandt, Ingo

    2001-09-01

    The present discussion of sociobiological approaches to ethnic nepotism takes Pierre van den Berghe's theory as a starting point. Two points, which have not been addressed in former analyses, are considered to be of particular importance. It is argued that the behavioral mechanism of ethnic nepotism -- as understood by van den Berghe -- cannot explain ethnic boundaries and attitudes. In addition, I show that van den Berghe's central premise concerning ethnic nepotism is in contradiction to Hamilton's formula, the essential principle of kin selection theory. It is further discussed how other approaches that make reference to ethnic nepotism are related to van den Berghe's account and its problems. I conclude with remarks on the evolutionary explanation of ethnic phenomena. PMID:16859334

  3. Misconceptions in Van den Broeck's representation of misconceptions about learning disability research.

    PubMed

    Willson, Victor L; Reynolds, Cecil R

    2002-01-01

    The methods and conclusions of Van den Broeck (in this issue) are evaluated from two perspectives: (a) statistical considerations and (b) theoretical models of IQ and achievement, specifically reading achievement. We consider the statistical model proposed by Van den Broeck for the regression-based discrepancy model (RDM) to be either irrelevant or conceptually inconsistent with current models of IQ and achievement. The resulting simulation produced exemplar cases that are not realistic in terms of practice. The theoretical representations of IQ and achievement were, in our understanding, inconsistent with contemporary models of either. We suggest that acceptable models support the use of the RDM as it has been proposed by us and by others as one component of the determination of the presence or absence of a learning disability. PMID:15493317

  4. Comment to the Article by van Arensbergen and van den Besselaar "The Selection of Scientific Talent in the Allocation of Research Grants"

    ERIC Educational Resources Information Center

    Maessen, K. M. H.

    2012-01-01

    The article entitled "The selection of scientific talent in the allocation of research grants" by van Arensbergen and van den Besselaar published in "Higher Education Policy" 25/3 (2012) is based on research that both researchers carried out on behalf of The Netherlands Organisation for Scientific Research. In this comment, we want to address…

  5. A comprehensive photometric study of dynamically evolved small van den Bergh-Hagen open clusters

    NASA Astrophysics Data System (ADS)

    Piatti, Andrés E.

    2016-09-01

    We present results from Johnson UBV, Kron-Cousins RI and Washington CT1T2 photometries for seven van den Bergh-Hagen (vdBH) open clusters, namely, vdBH 1, 10, 31, 72, 87, 92, and 118. The high-quality, multi-band photometric data sets were used to trace the cluster stellar density radial profiles and to build colour-magnitude diagrams (CMDs) and colour-colour (CC) diagrams from which we estimated their structural parameters and fundamental astrophysical properties. The clusters in our sample cover a wide age range, from ˜ 60 Myr up to 2.8 Gyr, are of relatively small size (˜ 1 - 6 pc) and are placed at distances from the Sun which vary between 1.8 and 6.3 kpc, respectively. We also estimated lower limits for the cluster present-day masses as well as half-mass relaxation times (tr). The resulting values in combination with the structural parameter values suggest that the studied clusters are in advanced stages of their internal dynamical evolution (age/tr ˜ 20 - 320), possibly in the typical phase of those tidally filled with mass segregation in their core regions. Compared to open clusters in the solar neighbourhood, the seven vdBH clusters are within more massive (˜ 80 - 380M$⊙$), with higher concentration parameter values (c ˜ 0.75-1.15) and dynamically evolved ones.

  6. Mutations in SCARF2 Are Responsible for Van Den Ende-Gupta Syndrome

    PubMed Central

    Anastasio, Natascia; Ben-Omran, Tawfeg; Teebi, Ahmad; Ha, Kevin C.H.; Lalonde, Emilie; Ali, Rehab; Almureikhi, Mariam; Der Kaloustian, Vazken M.; Liu, Junhui; Rosenblatt, David S.; Majewski, Jacek; Jerome-Majewska, Loydie A.

    2010-01-01

    Van Den Ende-Gupta syndrome (VDEGS) is an extremely rare autosomal-recessive disorder characterized by distinctive craniofacial features, which include blepharophimosis, malar and/or maxillary hypoplasia, a narrow and beaked nose, and an everted lower lip. Other features are arachnodactyly, camptodactyly, peculiar skeletal abnormalities, and normal development and intelligence. We present molecular data on four VDEGS patients from three consanguineous Qatari families belonging to the same highly inbred Bedouin tribe. The patients were genotyped with SNP microarrays, and a 2.4 Mb homozygous region was found on chromosome 22q11 in an area overlapping the DiGeorge critical region. This region contained 44 genes, including SCARF2, a gene that is expressed during development in a number of mouse tissues relevant to the symptoms described above. Sanger sequencing identified a missense change, c.773G>A (p.C258Y), in exon 4 in the two closely related patients and a 2 bp deletion in exon 8, c.1328_1329delTG (p.V443DfsX83), in two unrelated individuals. In parallel with the candidate gene approach, complete exome sequencing was used to confirm that SCARF2 was the gene responsible for VDEGS. SCARF2 contains putative epidermal growth factor-like domains in its extracellular domain, along with a number of positively charged residues in its intracellular domain, indicating that it may be involved in intracellular signaling. However, the function of SCARF2 has not been characterized, and this study reports that phenotypic effects can be associated with defects in the scavenger receptor F family of genes. PMID:20887961

  7. Peter Pan.

    ERIC Educational Resources Information Center

    Storr, Catherine

    1992-01-01

    Offers a contemporary view of J. M. Barrie's life and his classic story, "Peter Pan." Suggests that "Peter Pan" does not really speak for today's children and that the time for Peter Pan's retirement has come. (PRA)

  8. Diagnosis of Van den Ende-Gupta syndrome: Approach to the Marden-Walker-like spectrum of disorders.

    PubMed

    Niederhoffer, Karen Y; Fahiminiya, Somayyeh; Eydoux, Patrice; Mawson, John; Nishimura, Gen; Jerome-Majewska, Loydie A; Patel, Millan S

    2016-09-01

    Marden-Walker syndrome is challenging to diagnose, as there is significant overlap with other multi-system congenital contracture syndromes including Beals congenital contractural arachnodactyly, D4ST1-Deficient Ehlers-Danlos syndrome (adducted thumb-clubfoot syndrome), Schwartz-Jampel syndrome, Freeman-Sheldon syndrome, Cerebro-oculo-facio-skeletal syndrome, and Van den Ende-Gupta syndrome. We discuss this differential diagnosis in the context of a boy from a consanguineous union with Van den Ende-Gupta syndrome, a diagnosis initially confused by the atypical presence of intellectual disability. SNP microarray and whole exome sequencing identified a homozygous frameshift mutation (p.L870V) in SCARF2 and predicted damaging mutations in several genes, most notably DGCR2 (p.P75L) and NCAM2 (p.S147G), both possible candidates for this child's intellectual disability. We review distinguishing features for each Marden-Walker-like syndrome and propose a clinical algorithm for diagnosis among this spectrum of disorders. © 2016 Wiley Periodicals, Inc. PMID:27375131

  9. Sclerocornea in a Patient with Van Den Ende–Gupta Syndrome Homozygous for a SCARF2 Microdeletion

    PubMed Central

    Migliavacca, Michele P.; Sobreira, Nara L. M.; Antonialli, Graziela P.M.; Oliveira, Mariana M.; Melaragno, Maria Isabel S.A.; Casteels, Ingele; de Ravel, Thomy; Brunoni, Decio; Valle, David; Perez, Ana Beatriz A.

    2015-01-01

    Van den Ende–Gupta Syndrome (VDEGS) is an autosomal recessive disorder characterized by blepharophimosis, distinctive nose, hypoplastic maxilla, and skeletal abnormalities. Using homozygosity mapping in four VDEGS patients from three consanguineous families, Anastacio et al. [Anastacio et al. (2010); Am J Hum Genet 87:553–559] identified homozygous mutations in SCARF2, located at 22q11.2. Bedeschi et al. [2011] described a VDEGS patient with sclerocornea and cataracts with compound heterozygosity for the common 22q11.2 microdeletion and a hemizygous SCARF2 mutation. Because sclerocornea had been described in DiGeorge-velo-cardio-facial syndrome but not in VDEGS, they suggested that the ocular abnormalities were caused by the 22q11.2 microdeletion. We report on a 23-year-old male who presented with bilateral sclerocornea and the VDGEGS phenotype who was subsequently found to be homozygous for a 17 bp deletion in exon 4 of SCARF2. The occurrence of bilateral sclerocornea in our patient together with that of Bedeschi et al., suggests that the full VDEGS phenotype may include sclerocornea resulting from homozygosity or compound heterozygosity for loss of function variants in SCARF2. PMID:24478002

  10. Molecular Characterization of Three Canine Models of Human Rare Bone Diseases: Caffey, van den Ende-Gupta, and Raine Syndromes

    PubMed Central

    Hytönen, Marjo K.; Arumilli, Meharji; Lappalainen, Anu K.; Owczarek-Lipska, Marta; Jagannathan, Vidhya; Hundi, Sruthi; Salmela, Elina; Venta, Patrick; Sarkiala, Eva; Jokinen, Tarja; Gorgas, Daniela; Kere, Juha; Nieminen, Pekka

    2016-01-01

    One to two percent of all children are born with a developmental disorder requiring pediatric hospital admissions. For many such syndromes, the molecular pathogenesis remains poorly characterized. Parallel developmental disorders in other species could provide complementary models for human rare diseases by uncovering new candidate genes, improving the understanding of the molecular mechanisms and opening possibilities for therapeutic trials. We performed various experiments, e.g. combined genome-wide association and next generation sequencing, to investigate the clinico-pathological features and genetic causes of three developmental syndromes in dogs, including craniomandibular osteopathy (CMO), a previously undescribed skeletal syndrome, and dental hypomineralization, for which we identified pathogenic variants in the canine SLC37A2 (truncating splicing enhancer variant), SCARF2 (truncating 2-bp deletion) and FAM20C (missense variant) genes, respectively. CMO is a clinical equivalent to an infantile cortical hyperostosis (Caffey disease), for which SLC37A2 is a new candidate gene. SLC37A2 is a poorly characterized member of a glucose-phosphate transporter family without previous disease associations. It is expressed in many tissues, including cells of the macrophage lineage, e.g. osteoclasts, and suggests a disease mechanism, in which an impaired glucose homeostasis in osteoclasts compromises their function in the developing bone, leading to hyperostosis. Mutations in SCARF2 and FAM20C have been associated with the human van den Ende-Gupta and Raine syndromes that include numerous features similar to the affected dogs. Given the growing interest in the molecular characterization and treatment of human rare diseases, our study presents three novel physiologically relevant models for further research and therapy approaches, while providing the molecular identity for the canine conditions. PMID:27187611

  11. Molecular Characterization of Three Canine Models of Human Rare Bone Diseases: Caffey, van den Ende-Gupta, and Raine Syndromes.

    PubMed

    Hytönen, Marjo K; Arumilli, Meharji; Lappalainen, Anu K; Owczarek-Lipska, Marta; Jagannathan, Vidhya; Hundi, Sruthi; Salmela, Elina; Venta, Patrick; Sarkiala, Eva; Jokinen, Tarja; Gorgas, Daniela; Kere, Juha; Nieminen, Pekka; Drögemüller, Cord; Lohi, Hannes

    2016-05-01

    One to two percent of all children are born with a developmental disorder requiring pediatric hospital admissions. For many such syndromes, the molecular pathogenesis remains poorly characterized. Parallel developmental disorders in other species could provide complementary models for human rare diseases by uncovering new candidate genes, improving the understanding of the molecular mechanisms and opening possibilities for therapeutic trials. We performed various experiments, e.g. combined genome-wide association and next generation sequencing, to investigate the clinico-pathological features and genetic causes of three developmental syndromes in dogs, including craniomandibular osteopathy (CMO), a previously undescribed skeletal syndrome, and dental hypomineralization, for which we identified pathogenic variants in the canine SLC37A2 (truncating splicing enhancer variant), SCARF2 (truncating 2-bp deletion) and FAM20C (missense variant) genes, respectively. CMO is a clinical equivalent to an infantile cortical hyperostosis (Caffey disease), for which SLC37A2 is a new candidate gene. SLC37A2 is a poorly characterized member of a glucose-phosphate transporter family without previous disease associations. It is expressed in many tissues, including cells of the macrophage lineage, e.g. osteoclasts, and suggests a disease mechanism, in which an impaired glucose homeostasis in osteoclasts compromises their function in the developing bone, leading to hyperostosis. Mutations in SCARF2 and FAM20C have been associated with the human van den Ende-Gupta and Raine syndromes that include numerous features similar to the affected dogs. Given the growing interest in the molecular characterization and treatment of human rare diseases, our study presents three novel physiologically relevant models for further research and therapy approaches, while providing the molecular identity for the canine conditions. PMID:27187611

  12. Unmasking of a Recessive SCARF2 Mutation by a 22q11.12 de novo Deletion in a Patient with Van den Ende-Gupta Syndrome

    PubMed Central

    Bedeschi, M.F.; Colombo, L.; Mari, F.; Hofmann, K.; Rauch, A.; Gentilin, B.; Renieri, A.; Clerici, D.

    2011-01-01

    Van den Ende-Gupta syndrome (VDEGS) is a congenital condition characterized by craniofacial and skeletal manifestations, specifically blepharophimosis, malar and maxillary hypoplasia, distinctive nose, arachnocamptodactyly, and long slender bones of the hands and feet. To date, only 24 patients have been described. It is generally thought that the syndrome is transmitted by an autosomal recessive mode of inheritance, although evidence for genetic heterogeneity has recently been presented. We report on a girl followed from birth up to 3 years of life with a set of peculiar minor anomalies, arachnocamptodactyly of hands and feet, characteristic of VDEGS in association with a 22q11.12 deletion. Recently, the VDEGS gene was mapped to the DiGeorge syndrome region on 22q11.2, and homozygous mutations in the SCARF2 gene were identified. We now report the first patient with VDEGS due to compound heterozygosity for the common 22q11.2 microdeletion and a hemizygous SCARF2 splice site mutation. PMID:22140376

  13. Loving Peter Pan.

    ERIC Educational Resources Information Center

    Kinkaid, James R.

    2003-01-01

    Explores the story of "Peter Pan." Considers its creation, its role on the stage, and its impact on society. Considers how "Peter Pan" is about the inability to have make-believe and the true stick together: it dramatizes an artistic failure, the failure to make the vision of the play successful. (SG)

  14. Remembering Peter Medway

    ERIC Educational Resources Information Center

    Hardcastle, John; Clements, Simon

    2015-01-01

    Peter Medway was an exceptionally able teacher, researcher and thinker, and his work throws light on governments, inspectors and educators. In the early 1960s, Peter met a theory which "established language as a major means of constructing our realities". Later, after teaching English in secondary schools for two decades, he reflected on…

  15. Obituary: Peter E. Brommer

    NASA Astrophysics Data System (ADS)

    Buschow, K. H. J.; de Boer, F. R.; Degiorgi, L.; Jochemsen, R.; Wada, H.; Oostinga, Jeroen; van Wetering, Karine

    2016-07-01

    With great sadness we inform you that Dr P.E. Brommer, editor of Physica B: Condensed Matter Physics has passed away on March 23. Peter has been on the editorial board of the journal for more than 10 years. He was very dedicated to the journal and performed his editorial work with great care and sincerity. For all of us, the opinion and judgment of Peter have always been of crucial importance. We are very grateful for what Peter has meant for the journal. We will enormously miss him.

  16. Peter Pindar (John Wolcot).

    ERIC Educational Resources Information Center

    Vales, Robert L.

    This book is designed as an introduction to John Wolcot's works for the general reader, the college student, and the college teacher. Wolcot, whose pen name was Peter Pindar, wrote topical satire on public personalities of the eighteenth century, and his methods of criticism are the motif which guides each chapter and which unites all the satires…

  17. Peter Sis: Gifted Creator.

    ERIC Educational Resources Information Center

    Brodie, Carolyn S.

    2003-01-01

    Presents a brief biography of Peter Sis, an author and illustrator of children's books. Includes awards he has won; extension activities; and annotated bibliographies of books written and illustrated by Sis, selected books illustrated by Sis, audiobooks, videorecordings, sources for biographical information, and information on the Web. (LRW)

  18. The Peter What? A Challenge to the Peter Principle

    ERIC Educational Resources Information Center

    Batten, Joe D.

    1971-01-01

    The Peter Principle" is delightful reading particularly for the obsolete or near obsolete person who wants a reassuring palliative for the expedient batch of obsolete practices for which he has opted. (Author/NL)

  19. Peter Elbow's Rhetoric of Reading.

    ERIC Educational Resources Information Center

    Gardiner, Ellen

    1995-01-01

    Claims that Peter Elbow's rhetoric of reading has been oversimplified by applications of taxonomic critiques. Shows how Elbow not only does not ignore the social, but that in fact Elbow's rhetoric tends to try to control it. (HB)

  20. FOREWORD: Peter Clay Eklund: a scientific biography Peter Clay Eklund: a scientific biography

    NASA Astrophysics Data System (ADS)

    Cole, Milton W.; Crespi, Vincent H.; Dresselhaus, Gene F.; Dresselhaus, Mildred S.; Mahan, Gerald D.; Sofo, Jorge O.

    2010-08-01

    Peter Eklund grew up in Southern California and attended the University of California at Berkeley, majoring in physics. After working for one year at the Lockheed Missile and Space Company in Sunnyvale, California, he left to pursue graduate studies at Purdue University. There he carried out PhD research in strongly correlated electron and phonon systems under the supervision of J M Honig and L L van Zandt. Peter joined the group of Millie and Gene Dresselhaus at MIT in 1974 as a Postdoctoral Fellow after one year as an instructor at the University of Kentucky. At MIT, he continued work on strongly correlated systems in collaboration with Professor David Adler (who had an adjoining office), but for the most part he got excited about sp2 carbon systems and graphite intercalation compounds, a new research direction which the Dresselhaus group had started one year before Peter's arrival at MIT. Over the next 35 years Peter, Millie and Gene co-authored over 50 research articles, several review articles, and a big nine-hundred-and-fifty page book. In 1974, they saw graphite intercalation compounds as a long-neglected research direction of great promise. They studied these new materials together over the next 16 years, focusing on their optical spectroscopy. Their pioneering vibrational spectroscopy studies provided a means to characterize the fundamental properties of carbon materials. Optical spectroscopy became a centerpiece in the research portfolios of all three, both when they were together at MIT and after Peter left for the University of Kentucky in 1977 to start his independent career as an Assistant Professor of Physics. Peter became a full Professor at Kentucky in 1986. He continued to work with Millie and Gene and also acquired an ever-expanding network of students, postdocs and collaborators. As each new carbon nanostructure emerged—graphite intercalation compounds, fullerenes, carbon nanotubes, and most recently graphene—Peter was at the cutting edge

  1. An Interview with Peter Elbow.

    ERIC Educational Resources Information Center

    Peinado, Kelly

    1997-01-01

    Solicits the opinion of writing specialist Peter Elbow on two-year colleges, whether writing can be taught, whether literature has a place in the composition classroom, and whether teachers with literature degrees make good writing teachers. Discusses what works with developmental writers, and other topics. (PA)

  2. Peter & Jane: A Program Showcase

    ERIC Educational Resources Information Center

    Kalinowski, Michael

    2008-01-01

    This article features the early childhood programs at Peter & Jane Kindergarten located in Petaling Java, Malaysia. The primary purpose of the programs is to lay a strong foundation for a lifelong love of learning in each child. According to principal Patricia Teh, the activities are funded by parent fees and serve children two to six years of…

  3. What Would Peter Drucker Say?

    ERIC Educational Resources Information Center

    Sundre, Steven M.; Raisch, C. Daniel

    2002-01-01

    Applies observations and advice by management guru Peter F. Drucker to the role of school system leaders. Topics include the customer as king, the continually changing definition of success, effective time management, the ethical dimension of decision making, and performance-based leadership (MLF)

  4. Richard Peters and Valuing Authenticity

    ERIC Educational Resources Information Center

    Degenhardt, M. A. B.

    2009-01-01

    Richard Peters has been praised for the authenticity of his philosophy, and inquiry into aspects of the development of his philosophy reveals a profound authenticity. Yet authenticity is something he seems not to favour. The apparent paradox is resolved by observing historical changes in the understanding of authenticity as an important value.…

  5. FOREWORD: Peter Clay Eklund: a scientific biography Peter Clay Eklund: a scientific biography

    NASA Astrophysics Data System (ADS)

    Cole, Milton W.; Crespi, Vincent H.; Dresselhaus, Gene F.; Dresselhaus, Mildred S.; Mahan, Gerald D.; Sofo, Jorge O.

    2010-08-01

    Peter Eklund grew up in Southern California and attended the University of California at Berkeley, majoring in physics. After working for one year at the Lockheed Missile and Space Company in Sunnyvale, California, he left to pursue graduate studies at Purdue University. There he carried out PhD research in strongly correlated electron and phonon systems under the supervision of J M Honig and L L van Zandt. Peter joined the group of Millie and Gene Dresselhaus at MIT in 1974 as a Postdoctoral Fellow after one year as an instructor at the University of Kentucky. At MIT, he continued work on strongly correlated systems in collaboration with Professor David Adler (who had an adjoining office), but for the most part he got excited about sp2 carbon systems and graphite intercalation compounds, a new research direction which the Dresselhaus group had started one year before Peter's arrival at MIT. Over the next 35 years Peter, Millie and Gene co-authored over 50 research articles, several review articles, and a big nine-hundred-and-fifty page book. In 1974, they saw graphite intercalation compounds as a long-neglected research direction of great promise. They studied these new materials together over the next 16 years, focusing on their optical spectroscopy. Their pioneering vibrational spectroscopy studies provided a means to characterize the fundamental properties of carbon materials. Optical spectroscopy became a centerpiece in the research portfolios of all three, both when they were together at MIT and after Peter left for the University of Kentucky in 1977 to start his independent career as an Assistant Professor of Physics. Peter became a full Professor at Kentucky in 1986. He continued to work with Millie and Gene and also acquired an ever-expanding network of students, postdocs and collaborators. As each new carbon nanostructure emerged—graphite intercalation compounds, fullerenes, carbon nanotubes, and most recently graphene—Peter was at the cutting edge

  6. R. S. Peters and the Periphery

    ERIC Educational Resources Information Center

    Haynes, Bruce

    2013-01-01

    Paul Hirst claimed that Richard Peters "revolutionised philosophy of education". This does not accord with my experience in the Antipodean periphery. My experience of the work of Wittgenstein, Austin and Kovesi before reading Peters and Dewey, Kuhn and Toulmin subsequently meant that Peters was a major but not revolutionary figure in my…

  7. An interview with Peter Lawrence.

    PubMed

    Vicente, Catarina

    2016-01-15

    Peter Lawrence, FRS, is a fly geneticist based at the Department of Zoology at the University of Cambridge. During his illustrious career he has carried out pioneering work on pattern formation and polarity, and his contributions have been recognised by many honours, including the Prince of Asturias prize with Gines Morata and election to the Royal Swedish Academy of Sciences. He is also an outspoken critic of the current scientific system and particularly how it affects young scientists. We recently had the opportunity to chat with Peter, and we asked him about the influence of his mentor Sir V. B. Wigglesworth, writing his first grant at age 65 and his time as an editor of Development. PMID:26786208

  8. A Hundred Years of Peter Pan

    ERIC Educational Resources Information Center

    Hollindale, Peter

    2005-01-01

    The centenary of the first performance of J. M. Barrie's Peter Pan was celebrated in December 2004. Taking account of the various events in Britain to mark the occasion--newspaper articles, radio and television programmes, retrospects in the original theatre--this article examines the status and popularity of Peter Pan after a hundred years. The…

  9. Why General Education? Peters, Hirst and History

    ERIC Educational Resources Information Center

    White, John

    2009-01-01

    Richard Peters argued for a general education based largely on the study of truth-seeking subjects for its own sake. His arguments have long been acknowledged as problematic. There are also difficulties with Paul Hirst's arguments for a liberal education, which in part overlap with Peters'. Where justification fails, can historical explanation…

  10. Peter H. Rossi: Formative for Program Evaluation

    ERIC Educational Resources Information Center

    Lipsey, Mark W.

    2007-01-01

    This article discusses the significant contributions of Peter H. Rossi to the field of program evaluation. It was the publication of "Evaluation: A Systematic Approach" by Peter Rossi, Howard Freeman, and Sonia Rosenbaum in 1979 that most emphatically marked the point at which program evaluation had clearly consolidated as a distinct field of…

  11. Was Peters Nearly Right about Education?

    ERIC Educational Resources Information Center

    Barrow, Robin

    2009-01-01

    Richard Peters pioneered a form of philosophical analysis in relation to educational discourse that was criticised by some at the time and is today somewhat out of fashion. This paper argues that much of the objection to Peters' methodology is based on a misunderstanding of what it does and does not involve, that consequently philosophical…

  12. Peter Pan: The Text and the Myth.

    ERIC Educational Resources Information Center

    Hollindale, Peter

    1993-01-01

    Shows how the critical reception of J. M. Barrie's "Peter Pan" has varied widely since its publication. Describes the mythical qualities of the Peter Pan character and gives reasons why the story is still popular with children and why it should continue to be taught and read. (HB)

  13. Pearn Peter Niiler (1937-2010)

    NASA Astrophysics Data System (ADS)

    Schmitz, William J., Jr.; Large, William G.

    2011-05-01

    Peter Niiler, great friend, valued colleague, and AGU Fellow since 1986, will be remembered for his scientific achievements and as one of the most colorful physical oceanographers of his generation. Indeed, the Tropic Heat experiment's colors of mauve on pink, complete with Peter's matching ensemble, remain a vivid memory of that otherwise orthodox 1980s program championed by Peter to target equatorial Pacific mixing. Peter always sought understanding: to get things right for the right reason. Therefore, he held a healthy skepticism of numerical modeling and remote sensing, while utilizing both satellites and his own brand of diagnostic modeling. Peter's science motives were noble and would lead him to fight the good fight when necessary, especially when advocating his views on the Gulf Stream path, trapped inertial currents, heat and vorticity balances, and other subjects evoking his passion.

  14. Autonomy in R. S. Peters' Educational Theory

    ERIC Educational Resources Information Center

    Cuypers, Stefaan E.

    2009-01-01

    Autonomy is, among other things, an actual psychological condition, a capacity that can be developed, and an educational ideal. This paper contextualises, analyses, criticises and extends the theory of Richard S. Peters on these three aspects of autonomy.

  15. Peter Gabriel Talks With Space Station Crew

    NASA Video Gallery

    Singer-songwriter Peter Gabriel and family visit Mission Control Houston and talk with Expedition 33 Commander Kevin Ford and Flight Engineers Tom Marshburn and Chris Hadfield aboard the Internatio...

  16. Peter Frampton Talks to Station Crew

    NASA Video Gallery

    Rocker Peter Frampton and his band are introduced by astronaut Ron Garan to Commander Mike Fossum and Flight Engineers Satoshi Furukawa and Sergei Volkov aboard the International Space Station duri...

  17. John Peter Zenger, Battler for Freedom

    ERIC Educational Resources Information Center

    Wallerstein, Gerry

    1974-01-01

    Examines the freedom of the press precedent set by the John Peter Zenger case in 1743 and considers its application to such current events as the jailing of reporters for not disclosing news sources. (RB)

  18. Whole exome sequence analysis of Peters anomaly.

    PubMed

    Weh, Eric; Reis, Linda M; Happ, Hannah C; Levin, Alex V; Wheeler, Patricia G; David, Karen L; Carney, Erin; Angle, Brad; Hauser, Natalie; Semina, Elena V

    2014-12-01

    Peters anomaly is a rare form of anterior segment ocular dysgenesis, which can also be associated with additional systemic defects. At this time, the majority of cases of Peters anomaly lack a genetic diagnosis. We performed whole exome sequencing of 27 patients with syndromic or isolated Peters anomaly to search for pathogenic mutations in currently known ocular genes. Among the eight previously recognized Peters anomaly genes, we identified a de novo missense mutation in PAX6, c.155G>A, p.(Cys52Tyr), in one patient. Analysis of 691 additional genes currently associated with a different ocular phenotype identified a heterozygous splicing mutation c.1025+2T>A in TFAP2A, a de novo heterozygous nonsense mutation c.715C>T, p.(Gln239*) in HCCS, a hemizygous mutation c.385G>A, p.(Glu129Lys) in NDP, a hemizygous mutation c.3446C>T, p.(Pro1149Leu) in FLNA, and compound heterozygous mutations c.1422T>A, p.(Tyr474*) and c.2544G>A, p.(Met848Ile) in SLC4A11; all mutations, except for the FLNA and SLC4A11 c.2544G>A alleles, are novel. This is the first study to use whole exome sequencing to discern the genetic etiology of a large cohort of patients with syndromic or isolated Peters anomaly. We report five new genes associated with this condition and suggest screening of TFAP2A and FLNA in patients with Peters anomaly and relevant syndromic features and HCCS, NDP and SLC4A11 in patients with isolated Peters anomaly. PMID:25182519

  19. Whole exome sequence analysis of Peters anomaly

    PubMed Central

    Weh, Eric; Reis, Linda M.; Happ, Hannah C.; Levin, Alex V.; Wheeler, Patricia G.; David, Karen L.; Carney, Erin; Angle, Brad; Hauser, Natalie

    2015-01-01

    Peters anomaly is a rare form of anterior segment ocular dysgenesis, which can also be associated with additional systemic defects. At this time, the majority of cases of Peters anomaly lack a genetic diagnosis. We performed whole exome sequencing of 27 patients with syndromic or isolated Peters anomaly to search for pathogenic mutations in currently known ocular genes. Among the eight previously recognized Peters anomaly genes, we identified a de novo missense mutation in PAX6, c.155G>A, p.(Cys52Tyr), in one patient. Analysis of 691 additional genes currently associated with a different ocular phenotype identified a heterozygous splicing mutation c.1025+2T>A in TFAP2A, a de novo heterozygous nonsense mutation c.715C>T, p.(Gln239*) in HCCS, a hemizygous mutation c.385G>A, p.(Glu129Lys) in NDP, a hemizygous mutation c.3446C>T, p.(Pro1149Leu) in FLNA, and compound heterozygous mutations c.1422T>A, p.(Tyr474*) and c.2544G>A, p.(Met848Ile) in SLC4A11; all mutations, except for the FLNA and SLC4A11 c.2544G>A alleles, are novel. This is the frst study to use whole exome sequencing to discern the genetic etiology of a large cohort of patients with syndromic or isolated Peters anomaly. We report five new genes associated with this condition and suggest screening of TFAP2A and FLNA in patients with Peters anomaly and relevant syndromic features and HCCS, NDP and SLC4A11 in patients with isolated Peters anomaly. PMID:25182519

  20. Peter J Turner: an inventive optometrist.

    PubMed

    Frederikson, Lesley G; Jacobs, Robert J

    2007-11-01

    Machines are Peter Turner's life. They always have been, are now and probably always will be. He can blame his parents for this because despite urging Peter to become an optometrist they gave him inventive genes, a love of technology and holiday work in a factory fitting and turning, and welding. In the 30 years since completing his State Diploma in Optics in New Zealand (SDONZ), Peter has designed and developed three key pieces of optical equipment: a Sun-Following Radio Telescope, a CCTV read/write system and the Berkeley Glare & Acuity Test (BEGAT). He has also completed myriad technological innovations for friends and family ranging from a motorised chair and stand unit for optometric rooms to components for venetian blind manufacturing. PMID:17958574

  1. PEOPLE IN PHYSICS: Interview with Peter Higgs

    NASA Astrophysics Data System (ADS)

    Fancey, Conducted by Norman

    1998-01-01

    Peter Higgs, FRSE, FRS held until recently a personal chair in theoretical physics at the University of Edinburgh and is now an emeritus professor. Peter is well known for predicting the existence of a new particle, the Higgs boson - as yet unconfirmed. He has been awarded a number of prizes in recognition of his work, most recently the Paul Dirac Medal and Prize for outstanding contributions to theoretical physics from the Institute of Physics and the 1997 High Energy and Particle Physics Prize by the European Physical Society.

  2. An Interview with Peter MacDonald.

    ERIC Educational Resources Information Center

    American Indian Journal, 1979

    1979-01-01

    Peter MacDonald, Chairman of the Navajo Nation, the largest tribe in the United States speaks to such issues as energy development/management, oil companies, Navajo-Hopi relocation legislation, traditionalism, and the role of the Council of Energy Resource Tribes. (RTS)

  3. Reading R. S. Peters on Education Today

    ERIC Educational Resources Information Center

    Cuypers, Stefaan E.; Martin, Christopher

    2009-01-01

    This introduction to this special issue offers an overview of R. S. Peters' seminal role in the development of modern philosophy of education, acknowledging the originality and range of his work, and indicating his continuing importance to the field. It explains the structure and organisation of the collection and provides a rationale for this…

  4. Peter Waterman and T-Matrix Methods

    NASA Technical Reports Server (NTRS)

    Mishchenko, M. I.; Martin, P.A.

    2013-01-01

    This paper summarizes the scientific legacy of Peter C. Waterman (1928-2012) who introduced concepts and theoretical techniques that have had a major impact on the fields of scattering by particles and particle groups, optical particletcharacterization, radiative transfer, and remote sensing. A biographical sketch is also included.

  5. Peter Waterman and T-matrix methods

    NASA Astrophysics Data System (ADS)

    Mishchenko, M. I.; Martin, P. A.

    2013-07-01

    This paper summarizes the scientific legacy of Peter C. Waterman (1928-2012) who introduced concepts and theoretical techniques that have had a major impact on the fields of scattering by particles and particle groups, optical particle characterization, radiative transfer, and remote sensing. A biographical sketch is also included.

  6. R. S. Peters: The Reasonableness of Ethics

    ERIC Educational Resources Information Center

    Haynes, Felicity

    2013-01-01

    This article will begin by examining the extent to which R. S. Peters merited the charge of analytic philosopher. His background in social psychology allowed him to become more pragmatic and grounded in social conventions and ordinary language than the analytic philosophers associated with empiricism, and his gradual shift from requiring internal…

  7. The Statue of Liberty Peter Max Style!

    ERIC Educational Resources Information Center

    Cunningham, Kathy

    2012-01-01

    The author's school is only 30 minutes from New York City, so every year when second-graders study towns and cities, the students do a project based on New York City landmarks. This year was the Statue of Liberty. The author introduced Peter Max's famous Pop art to her students, and explained that, as the art world kept changing, artists decided…

  8. Obituary: Peter Robert Wilson, 1929-2007

    NASA Astrophysics Data System (ADS)

    Snodgrass, Herschel B.

    2009-01-01

    It is with great sadness that I report the passing of Peter Robert Wilson, a well-known and well-loved figure in the solar physics community. Peter was on the faculty of the Department of Applied Mathematics at the University of Sydney for 39 years, and Chair of the department for 24 of these years. He was the author or co-author of more than 80 scientific research papers and a book, Solar and Stellar Activity Cycles (1994), published by Cambridge University Press. He died suddenly of a heart attack, at his home in Glebe, Australia, in the early morning of 11 November 2007. Peter was an organizer of, and participant in, many international conferences and workshops. He traveled extensively, holding visiting appointments at the University of Colorado (JILA), at Cambridge University, at the College de France (Paris), and at the California Institute of Technology [CalTech]. Most of his work was in the field of solar physics, but he also did some work on the philosophy of science and on tides. Peter came from a line of mathematicians. His father, Robert Wilson, immigrated to Australia from Glasgow in 1911, and became a mathematics teacher at Scotch College, a private school in Melbourne. There his name was changed to 'Bill' because 'Bob' was already taken." Peter's enjoyment of this story as characteristic of Australian academia (as any fan of Monty Python would understand) is indicative of his infectious sense of humor. In a similar vein, he claimed ancestry traced back to the eighteenth-century Scottish mathematician Alexander Wilson, Professor of Astronomy at the University of Glasgow. That Wilson is famous in the solar physics community for his discovery, known as the "Wilson Effect," of the photospheric depressions associated with sunspots. Peter himself could not resist writing a paper on this subject, and was delighted when the bait was taken by some less-informed colleagues who chided him for "naming an effect after himself." "Bill" Wilson married Naomi

  9. Peter Waterman and his scientific legacy

    NASA Technical Reports Server (NTRS)

    Mishchenko, Michael I.; Kahnert, Michael; Mackowski, Daniel W.; Wriedt, Thomas

    2013-01-01

    Peter C. Waterman, a giant figure in the theory of electromagnetic, acoustic, and elastic wave scattering, passed away on 3 June, 2012. In view of his fundamental contributions, which to a large degree have guided the progress of these disciplines over the past five decades and affected profoundly the multifaceted research published in the Journal of Quantitative Spectroscopy and Radiative Transfer (JQSRT), we felt that it would be appropriate to solicit papers for a special issue of JQSRT commemorating Peter Waterman's scientific legacy. This initiative was endorsed by the JQSRT management and has resulted in a representative collection of high-quality papers which have undergone the same peer scrutiny as any paper submitted to JQSRT.

  10. Jim Peters--sportsman, soldier, surgeon.

    PubMed

    Webb, David Rowan

    2013-11-01

    Jim Peters, a country boy who excelled academically and in the sporting arena was a Victorian urological pioneer. His passion for teaching and belief in the development of Australasian urology resulted in the establishment of two of Melbourne's earliest Urology Units (which are now major academic University departments), the creation of a formal urological training program and the promotion of Australian urology within the International urological community. PMID:24127670

  11. Peter V.Hobbs (1936-2005)

    NASA Astrophysics Data System (ADS)

    Wallace, John M.

    Peter Hobbs, a professor in the Department of Atmospheric Sciences at the University of Washington in Seattle, died of pancreatic cancer on 25 July 2005.Born in 1936, Hobbs experienced what he described as “a wild, adventurous youth on the streets of postwar London.” He engaged in competitive swimming and at age 13 held the title of Junior Boxing Champion of the County of Surrey.

  12. Obituary: Peter Robert Wilson, 1929-2007

    NASA Astrophysics Data System (ADS)

    Snodgrass, Herschel B.

    2009-01-01

    It is with great sadness that I report the passing of Peter Robert Wilson, a well-known and well-loved figure in the solar physics community. Peter was on the faculty of the Department of Applied Mathematics at the University of Sydney for 39 years, and Chair of the department for 24 of these years. He was the author or co-author of more than 80 scientific research papers and a book, Solar and Stellar Activity Cycles (1994), published by Cambridge University Press. He died suddenly of a heart attack, at his home in Glebe, Australia, in the early morning of 11 November 2007. Peter was an organizer of, and participant in, many international conferences and workshops. He traveled extensively, holding visiting appointments at the University of Colorado (JILA), at Cambridge University, at the College de France (Paris), and at the California Institute of Technology [CalTech]. Most of his work was in the field of solar physics, but he also did some work on the philosophy of science and on tides. Peter came from a line of mathematicians. His father, Robert Wilson, immigrated to Australia from Glasgow in 1911, and became a mathematics teacher at Scotch College, a private school in Melbourne. There his name was changed to 'Bill' because 'Bob' was already taken." Peter's enjoyment of this story as characteristic of Australian academia (as any fan of Monty Python would understand) is indicative of his infectious sense of humor. In a similar vein, he claimed ancestry traced back to the eighteenth-century Scottish mathematician Alexander Wilson, Professor of Astronomy at the University of Glasgow. That Wilson is famous in the solar physics community for his discovery, known as the "Wilson Effect," of the photospheric depressions associated with sunspots. Peter himself could not resist writing a paper on this subject, and was delighted when the bait was taken by some less-informed colleagues who chided him for "naming an effect after himself." "Bill" Wilson married Naomi

  13. Dens invaginatus (Type III B)

    PubMed Central

    Kallianpur, Shreenivas; Sudheendra, US; Kasetty, Sowmya; Joshi, Prathamesh

    2012-01-01

    Dens invaginatus or ‘dens in dente’ is a developmental malformation of the tooth resulting from infolding of the dental papilla before calcification. This article presents a case of dens invaginatus occurring in maxillary right lateral incisor of a 45-year-old male patient. The patient presented with pain and clinically missing maxillary right canine. The tooth was found to be non-vital. Radiographic examination revealed the tooth-in-tooth appearance of lateral incisor with a dilated pulp chamber. The crown of impacted canine was found within the pulp chamber of lateral incisor. Owing to this unique clinical presentation, both the lateral incisor and the impacted canine were extracted. Histopathologic examination confirmed the diagnosis of Dens invaginatus Type III B. A brief review on etiopathogenesis, radiographic features and treatment of dens invaginatus has also been included. PMID:22923901

  14. Mapping Van

    NASA Technical Reports Server (NTRS)

    1994-01-01

    A NASA Center for the Commercial Development of Space (CCDS) - developed system for satellite mapping has been commercialized for the first time. Global Visions, Inc. maps an area while driving along a road in a sophisticated mapping van equipped with satellite signal receivers, video cameras and computer systems for collecting and storing mapping data. Data is fed into a computerized geographic information system (GIS). The resulting amps can be used for tax assessment purposes, emergency dispatch vehicles and fleet delivery companies as well as other applications.

  15. Two New Letters by Denning

    NASA Astrophysics Data System (ADS)

    Beech, Martin

    2010-06-01

    Two letters written by W. F. Denning to R. P. Greg in March and April of 1879 that had been tucked into the folds of an 1876 edition of the British Association for the Advancement of Science Reports were recently found at the Carnegie Institution in Washington D.C. The letters are wonderfully preserved, and offer us a snap-shot of the work being performed by a young Denning at the time when his influence in the field of meteor studies was in its ascendency. The contents of these two letters is analyzed and placed within context to Denning's other publications and private life.

  16. Theories of Power, Poverty, and Law: In Commemoration of the Contributions of Peter Bachrach--Power, Law, and Final Thoughts: The Contributions of Peter Bachrach

    ERIC Educational Resources Information Center

    Schneider, Elizabeth M.

    2010-01-01

    I am pleased to be part of this symposium to celebrate the life and work of Peter Bachrach. Although my focus is the relevance of Peter's ideas of power to law, I want to begin with some personal comments as well as raise some final thoughts, drawing on others' contributions. Like so many of Peter's other students, I adored him. Peter's joy in…

  17. 77 FR 14773 - Vigue, Peter A.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Vigue, Peter A.; Notice of Filing Take notice that on March 6, 2012, Peter A. Vigue submitted for filing, an application for authority to hold interlocking positions, pursuant...

  18. R. S. Peters' Normative Conception of Education and Educational Aims

    ERIC Educational Resources Information Center

    Katz, Michael S.

    2009-01-01

    This article aims to highlight why R. S. Peters' conceptual analysis of "education" was such an important contribution to the normative field of philosophy of education. In the article, I do the following: 1) explicate Peters' conception of philosophy of education as a field of philosophy and explain his approach to the philosophical analysis of…

  19. Against the Corporate Culture Ideology: An Interview with Peter Mayo

    ERIC Educational Resources Information Center

    Suoranta, Juha

    2010-01-01

    This article presents an interview with Peter Mayo, author and expert in the field of sociology of adult education, on his major influences in this area, his books, and his views on the role of radical adult education and radical scholarship in the future. In the interview, Peter Mayo states that his initial view of adult education was quite a…

  20. 77 FR 26538 - Vigue, Peter A.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... Energy Regulatory Commission Vigue, Peter A.; Notice of Filing Take notice that on April 26, 2012, Peter A. Vigue submitted for filing, a supplement to the application for authority to hold interlocking..., but will not serve to make protestants parties to the proceeding. Any person wishing to become a...

  1. Ritual, Imitation and Education in R. S. Peters

    ERIC Educational Resources Information Center

    Warnick, Bryan R.

    2009-01-01

    This article reconstructs R. S. Peters' underlying theory of ritual in education, highlighting his proposed link between ritual and the imitation of teachers. Rituals set the stage for the imitation of teachers and they invite students to experience practices whose value is not easily discernable from the outside. For Peters, rituals facilitate…

  2. Rehabilitation: disability ethics versus Peter Singer.

    PubMed

    McPherson, Gary W; Sobsey, Dick

    2003-08-01

    This commentary discusses utilitarian bioethics currently articulated by Peter Singer, one of the most widely known bioethicists of the 21st century. His controversial concepts of personhood and replaceability have important implications for people with disabilities, caregivers, and rehabilitation in general. Singer suggests that people with severe disabilities should not be considered persons and therefore have no rights or status in ethical issues. In addition, he argues that, although some people with less severe disabilities qualify as persons, their potential quality of life is significantly compromised by disability and therefore it may be ethically desirable to eliminate them so that their resources can be used for someone with superior potential. We reject these ideas, and suggest that those involved in rehabilitation carefully consider these ideas because they imply that rehabilitation is an immoral act unless it results in full and typical function. PMID:12917869

  3. EPA VAN OPERATIONAL MANUAL

    EPA Science Inventory

    The manual generally describes the EPA Van, and discusses both its energy control system and Van operation. The manual includes instructions for the Van's transportation, setup, safety, troubleshooting, and maintenance. The Van is a mobile research unit, designed for testing in v...

  4. Pilot Peter Hoag and HL-10

    NASA Technical Reports Server (NTRS)

    1969-01-01

    Air Force Major Peter Hoag stands in front of the HL-10 Lifting Body. Maj. Hoag joined the HL-10 program in 1969 and made his first glide flight on June 6, 1969. He made a total of 8 flights in the HL-10. They included the fastest lifting-body flight, which reached Mach 1.861 on Feb. 18, 1970. The HL-10 was one of five heavyweight lifting-body designs flown at NASA's Flight Research Center (FRC--later Dryden Flight Research Center), Edwards, California, from July 1966 to November 1975 to study and validate the concept of safely maneuvering and landing a low lift-over-drag vehicle designed for reentry from space. Northrop Corporation built the HL-10 and M2-F2, the first two of the fleet of 'heavy' lifting bodies flown by the NASA Flight Research Center. The contract for construction of the HL-10 and the M2-F2 was $1.8 million. 'HL' stands for horizontal landing, and '10' refers to the tenth design studied by engineers at NASA's Langley Research Center, Hampton, Va. After delivery to NASA in January 1966, the HL-10 made its first flight on Dec. 22, 1966, with research pilot Bruce Peterson in the cockpit. Although an XLR-11 rocket engine was installed in the vehicle, the first 11 drop flights from the B-52 launch aircraft were powerless glide flights to assess handling qualities, stability, and control. In the end, the HL-10 was judged to be the best handling of the three original heavy-weight lifting bodies (M2-F2/F3, HL-10, X-24A). The HL-10 was flown 37 times during the lifting body research program and logged the highest altitude and fastest speed in the Lifting Body program. On Feb. 18, 1970, Air Force test pilot Peter Hoag piloted the HL-10 to Mach 1.86 (1,228 mph). Nine days later, NASA pilot Bill Dana flew the vehicle to 90,030 feet, which became the highest altitude reached in the program. Some new and different lessons were learned through the successful flight testing of the HL-10. These lessons, when combined with information from it's sister ship, the M2

  5. Solution of Peter Winkler's Pizza Problem

    NASA Astrophysics Data System (ADS)

    Cibulka, Josef; Kynčl, Jan; Mészáros, Viola; Stolař, Rudolf; Valtr, Pavel

    Bob cuts a pizza into slices of not necessarily equal size and shares it with Alice by alternately taking turns. One slice is taken in each turn. The first turn is Alice's. She may choose any of the slices. In all other turns only those slices can be chosen that have a neighbor slice already eaten. We prove a conjecture of Peter Winkler by showing that Alice has a strategy for obtaining 4/9 of the pizza. This is best possible, that is, there is a cutting and a strategy for Bob to get 5/9 of the pizza. We also give a characterization of Alice's best possible gain depending on the number of slices. For a given cutting of the pizza, we describe a linear time algorithm that computes Alice's strategy gaining at least 4/9 of the pizza and another algorithm that computes the optimal strategy for both players in any possible position of the game in quadratic time. We distinguish two types of turns, shifts and jumps. We prove that Alice can gain 4/9, 7/16 and 1/3 of the pizza if she is allowed to make at most two jumps, at most one jump and no jump, respectively, and the three constants are the best possible.

  6. Writing with Teachers: A Conversation with Peter Elbow.

    ERIC Educational Resources Information Center

    Bartholomae, David

    1995-01-01

    Provides a complete text of David Bartholomae's speech on the debate with compositionist Peter Elbow regarding the pros and cons of teaching either academic discourse or personal writing modes to undergraduates. (HB)

  7. Life and Scientific Work of Peter Guthrie Tait

    NASA Astrophysics Data System (ADS)

    Gilston Knott, Cargill

    2015-04-01

    Preface; 1. Memoir - Peter Guthrie Tait; 2. Experimental work; 3. Mathematical work; 4. Quaternions; 5. Thomson and Tait, 'Tand T', or Thomson and Tait's natural philosophy; 6. Other books; 7. Addresses, reviews, and correspondence; 8. Popular scientific articles; Bibliography; Index.

  8. Peter Holland: a pioneer of occupational medicine.

    PubMed Central

    Murray, R

    1992-01-01

    The earliest recorded occupational health service in this country was that established in a cotton spinning factory at Quarry Bank Mill in Cheshire. The mill was built in 1784 by Samuel Greg and his partners. They employed local labour and also some parish apprentices. Happily, Samuel Greg was a good christian and, having created a modern factory and a model village with a church and a school, he was equally concerned for the physical welfare of his employees. Accordingly, he appointed a doctor to make pre-employment examinations of the apprentices and to visit regularly to deal with the health problems of a community of some 400 people. The man he chose was Peter Holland of Sandlebridge, who had served his medical apprenticeship under Dr Charles White of Manchester. The first record of the employment of a doctor was in 1796, but from 1804 to 1845 (doubtless in response to the early factory legislation) each visit of the doctor was entered in a day book with either an indication of fitness to work or details of the treatment required. The complete record consists of two hardback foolscap notebooks that provide a fascinating insight into the medical practice of the times when the industrial revolution was just getting under way. One of the more interesting features is the preservation of medical secrecy. Dr Holland made his comments on the case in shorthand and his instructions in longhand. By a fortunate coincidence the key to the shorthand was discovered and this has now been largely transcribed. Although much of the content of the diaries is the day by day practice of medicine at the time, there are many illuminating glimpses of the early practice of occupational medicine. Images PMID:1606023

  9. Peter Holland: a pioneer of occupational medicine.

    PubMed

    Murray, R

    1992-06-01

    The earliest recorded occupational health service in this country was that established in a cotton spinning factory at Quarry Bank Mill in Cheshire. The mill was built in 1784 by Samuel Greg and his partners. They employed local labour and also some parish apprentices. Happily, Samuel Greg was a good christian and, having created a modern factory and a model village with a church and a school, he was equally concerned for the physical welfare of his employees. Accordingly, he appointed a doctor to make pre-employment examinations of the apprentices and to visit regularly to deal with the health problems of a community of some 400 people. The man he chose was Peter Holland of Sandlebridge, who had served his medical apprenticeship under Dr Charles White of Manchester. The first record of the employment of a doctor was in 1796, but from 1804 to 1845 (doubtless in response to the early factory legislation) each visit of the doctor was entered in a day book with either an indication of fitness to work or details of the treatment required. The complete record consists of two hardback foolscap notebooks that provide a fascinating insight into the medical practice of the times when the industrial revolution was just getting under way. One of the more interesting features is the preservation of medical secrecy. Dr Holland made his comments on the case in shorthand and his instructions in longhand. By a fortunate coincidence the key to the shorthand was discovered and this has now been largely transcribed. Although much of the content of the diaries is the day by day practice of medicine at the time, there are many illuminating glimpses of the early practice of occupational medicine. PMID:1606023

  10. Double Dens Invaginatus: Report of Three Cases

    PubMed Central

    Zengin, A. Zeynep; Sumer, A. Pinar; Celenk, Peruze

    2009-01-01

    Dens invaginatus results from an infolding of the outer surface of a tooth. The clinical importance of dens invaginatus results from the risk of pulpal disease. So, all clinicians should be aware of this anomaly. The presence of double dens invaginatus is extremely rare. This article presents three cases of double dens invaginatus in permanent maxillary lateral incisors, one with preventive restoration on its palatal surface. They were classified as double dens invaginatus because of two enamel lined invaginations presented in the crowns of these teeth. PMID:19262734

  11. Peter Elbow, Kenneth Burke, and the Idea of Magic.

    ERIC Educational Resources Information Center

    Briggs, John C.

    1991-01-01

    Asserts that the works of Peter Elbow and Kenneth Burke are valuable reference points because they problematize fundamental assumptions within the field of composition that pluralism and factional perspectives typically elide. Describes Elbow's rhetorical magic and shows how magic illuminates Burke's effort. Wonders whether Elbow and Burke…

  12. Edifying Violence: Peter Elbow and the Pedagogical Paradox.

    ERIC Educational Resources Information Center

    Briggs, John Channing

    1995-01-01

    Presents a critique of the common practice of writing instruction advocated by the well-known theorist Peter Elbow. Focuses on the paradox of pedagogical authority in writing classrooms. Reviews Elbow's writings in light of the problem of pedagogical authority. (HB)

  13. The Peter Shaw Award Acceptance Address: An Immigrant Sociologist

    ERIC Educational Resources Information Center

    Hollander, Paul

    2003-01-01

    This article presents the author's acceptance address for receiving the Peter Shaw award. In this address, the author, an immigrant sociologist, tells how this award helps to resolve questions and uncertainties he has as to the degree to which he can or should consider himself an American--about the extent to which he has become a part, a member…

  14. R. S. Peters and the Concept of Education

    ERIC Educational Resources Information Center

    Beckett, Kelvin Stewart

    2011-01-01

    In this essay Kelvin Beckett argues that Richard Peters's major work on education, "Ethics and Education," belongs on a short list of important texts we can all share. He argues this not because of the place it has in the history of philosophy of education, as important as that is, but because of the contribution it can still make to the future of…

  15. R. S. Peters' "The Justification of Education" Revisited

    ERIC Educational Resources Information Center

    Cuypers, Stefaan E.

    2012-01-01

    In his 1973 paper "The Justification of Education" R. S. Peters aspired to give a non-instrumental justification of education. Ever since, his so-called "transcendental argument" has been under attack and most critics conclude that it does not work. They have, however, thrown the baby away with the bathwater, when they furthermore concluded that…

  16. Peter Effect in the Preparation of Reading Teachers

    ERIC Educational Resources Information Center

    Binks-Cantrell, Emily; Washburn, Erin K.; Joshi, R. Malatesha; Hougen, Martha

    2012-01-01

    The Peter Effect (Applegate & Applegate, 2004) claimed that one cannot be expected to give what one does not possess. We applied this notion to reading teacher preparation and hypothesized that teacher educators who do not possess an understanding of basic language constructs would not prepare teacher candidates with an understanding of these…

  17. Team Leader: Tom Peters--TAP Information Services

    ERIC Educational Resources Information Center

    Library Journal, 2005

    2005-01-01

    Tom Peters packs 36 hours of work into the confines of a 24-hour day. Without breaking a sweat, he juggles multiple collaborative projects, which currently include an Illinois academic library shared storage facility; a multistate virtual reference and instruction service for blind and visually impaired individuals (InfoEyes); a virtual meeting…

  18. Advocating Science for All: An Interview with Peter J. Fensham

    ERIC Educational Resources Information Center

    Cardellini, Liberato

    2013-01-01

    After providing some glimpses of his private life, Peter Fensham, a leading figure of the prestigious Faculty of Education, Monash University (and now emeritus professor at Queensland University, Brisbane, Australia), gives some suggestions about the conditions that help students to learn meaningfully. He began his career in the field of physical…

  19. Marginal Experiments: Peter Brook and Stepping out Theatre Company

    ERIC Educational Resources Information Center

    Harpin, Anna

    2010-01-01

    This article juxtaposes the recent work of Peter Brook with a Bristol-based mental health service-user collective--Stepping Out Theatre Company. Informed by field-work with the company, this chapter explores the aesthetic and political relationship between professional, experimental theatre work and community-based performance practice. Drawing…

  20. My Journey with Peter: Moving Ideas that Matter

    ERIC Educational Resources Information Center

    Blyth, Dale A.

    2012-01-01

    Youth development lost a pioneer and a champion, Peter Benson, in October. Benson was a pioneer whose ideas mattered and a champion of approaches to research and its use in the community that has made a difference around the world. Benson's work, life, and spirit have helped transform people's understanding of young people, what it takes to…

  1. Portrait Face-Off: Gilbert Stuart vs. Peter Max

    ERIC Educational Resources Information Center

    Crumpecker, Cheryl

    2012-01-01

    When art classes are short and infrequent, it is always a challenge to meet required state and national standards. A unit comparing and contrasting Peter Max's Pop art portraits with the realistic style of Gilbert Stuart's presidential portraits provides an opportunity to address a huge number of these requirements. Focus can change with the age…

  2. Peters' Concept of "Education as Initiation": Communitarian or Individualist?

    ERIC Educational Resources Information Center

    Cotter, Richard

    2013-01-01

    A central element of Richard Peters' philosophy of education has been his analysis of "education as initiation". Understanding initiation is internally related to concepts of community and what it may mean to be a member. The concept of initiation assumes a mutually interdependent, dynamic relationship between the individual and community that…

  3. London in Space and Time: Peter Ackroyd and Will Self

    ERIC Educational Resources Information Center

    Green, Andrew

    2013-01-01

    This paper explores the treatment of London by two authors who are profoundly influenced by the concept of the power of place and the nature of urban space. The works of Peter Ackroyd, whose writings embody, according to Onega (1997, p. 208) "[a] yearning for mythical closure" where London is "a mystic centre of…

  4. Remembering Peter Drucker: inspiring the quality revolution in healthcare.

    PubMed

    Seeman, Neil; Brown, Adalsteinn D

    2006-01-01

    The authors review the late Peter Drucker's most significant writings, especially as they pertain to contemporary quality improvement principles in healthcare. In order to determine Drucker's most influential works, the authors conducted an empirical review of his impact by examining academic citations to his work and ideas. PMID:16548434

  5. Peter Drucker, Knowledge Work, and the Structure of Schools.

    ERIC Educational Resources Information Center

    Tucker, Marc S.

    1988-01-01

    Discusses Peter Drucker's recommendations in "The Age of Discontinuity" (1969) concerning the decline of manual work, the ascendancy of knowledge work, and the relationship between economic stability and an educated, productive work force. Applies Drucker's principles to the movement to restructure schools, which aims to make line workers…

  6. A Conversation with...Attila Pok & Peter Hanak.

    ERIC Educational Resources Information Center

    Cheney, Lynne V.

    1992-01-01

    Presents an interview with Hungarian historians Attila Pok and Peter Hanak. Explains the role of the Hungarian Academy of Sciences. Reveals how teachers and researchers functioned under Hungary's former socialist government. Discusses the shortage of educational resources in Hungary. Examines why intellectuals govern Hungary today. (SG)

  7. Revisiting van Hiele

    ERIC Educational Resources Information Center

    Papademetri-Kachrimani, Chrystalla

    2012-01-01

    In this paper I argue my opposition to the consensus which has dominated the literature that young children view shapes as a whole and pay no attention to shape structure and that geometrical thinking can be described through a hierarchical model formed by levels. This consensus is linked to van Hiele's weok by van Hiele-based research. In the…

  8. The posteriorly tilted dens. A normal variation mimicking a fractured dens.

    PubMed

    Swischuk, L E; Hayden, C K; Sarwar, M

    1979-02-26

    The normal dens occasionally can be posteriorly tilted and in such cases, can mimic a fractured, posteriorly tilted, dens. Differentiation of the two conditions depends on: [1] knowledge that this normal variation of the dens occurs, and [2] demonstrating that no fracture exists. In many cases, this latter determination can be accomplished on plain films, but in other cases, laminography is required. PMID:431988

  9. Theories of Power, Poverty, and Law: In Commemoration of the Contributions of Peter Bachrach--The Challenge of Peter Bachrach

    ERIC Educational Resources Information Center

    Lukes, Steven

    2010-01-01

    Peter Bachrach had a remarkable impact on those who encountered him in person and on generations of readers. Judith Baer vividly captures, among other things, his inspiring, emboldening influence on his students and the sheer fun it was to be with him. My recollections are of exciting, forward moving, intense, and probing arguments, in private and…

  10. Peter Wilcox: A new purple-skin, yellow flesh fresh market potato cultivar

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Peter Wilcox is a new, medium-maturing, purple-skin, yellow-flesh potato cultivar for fresh market. Peter Wilcox also produces light-colored chips, although it is being released primarily as a fresh market potato because of its skin and flesh colors. Tubers of Peter Wilcox are attractive, smooth, wi...

  11. Von Tondern nach Gotha. Der Astronom Peter Andreas Hansen, 1795 - 1874.

    NASA Astrophysics Data System (ADS)

    Strumpf, M.; Pehlemann, E.; Wolfschmidt, G.

    This companion booklet to an exposition in honor of Peter Andreas Hansen's 200th birthday contains three papers. Contents: 1. Peter Andreas Hansen - Leben und Wirken in Gotha (M. Strumpf). 2. Peter Andreas Hansens wissenschaftliches Werk (E. Pehlemann). 3. Beobachtungsinstrumente der Sternwarte Gotha zur Zeit Hansens (G. Wolfschmidt).

  12. Denning of grizzly bears in the Yellowstone National Park area

    USGS Publications Warehouse

    Judd, Steven L.; Knight, Richard R.; Blanchard, Bonnie M.

    1986-01-01

    Radiotelemetry was used to locate 101 grizzly bear (Ursus arctos) dens from 1975 to 1980; 35 dens were examined on the ground. Pregnant females denned in late October, and most other bears denned by mid-November. Duration of denning average 113, 132, and 170 days for males, females, and females with new cubs, respectively. Males emerged from mid-February to late March, followed by single females and females with yearlings and 2-year-olds. Females with new cubs emerged from early mid-April. Den sites were associated with moderate tree cover (26%-75% canopy cover) on 30°-60° slopes. Dens occurred on all aspects, although northerly exposures were most common. Grizzly bears usually dug new dens but occasionally used natural cavities or a den from a previous year. Males usually dug larger dens than females with young. Eight excavated and 2 natural dens of the 35 examined dens were used for more than 1 year.

  13. The DenA/DEN1 Interacting Phosphatase DipA Controls Septa Positioning and Phosphorylation-Dependent Stability of Cytoplasmatic DenA/DEN1 during Fungal Development

    PubMed Central

    Schinke, Josua; Kolog Gulko, Miriam; Christmann, Martin; Valerius, Oliver; Stumpf, Sina Kristin; Stirz, Margarita; Braus, Gerhard H.

    2016-01-01

    DenA/DEN1 and the COP9 signalosome (CSN) represent two deneddylases which remove the ubiquitin-like Nedd8 from modified target proteins and are required for distinct fungal developmental programmes. The cellular DenA/DEN1 population is divided into a nuclear and a cytoplasmatic subpopulation which is especially enriched at septa. DenA/DEN1 stability control mechanisms are different for the two cellular subpopulations and depend on different physical interacting proteins and the C-terminal DenA/DEN1 phosphorylation pattern. Nuclear DenA/DEN1 is destabilized during fungal development by five of the eight CSN subunits which target nuclear DenA/DEN1 for degradation. DenA/DEN1 becomes stabilized as a phosphoprotein at S243/S245 during vegetative growth, which is necessary to support further asexual development. After the initial phase of development, the newly identified cytoplasmatic DenA/DEN1 interacting phosphatase DipA and an additional developmental specific C-terminal phosphorylation site at serine S253 destabilize DenA/DEN1. Outside of the nucleus, DipA is co-transported with DenA/DEN1 in the cytoplasm between septa and nuclei. Deletion of dipA resulted in increased DenA/DEN1 stability in a strain which is unresponsive to illumination. The mutant strain is dysregulated in cytokinesis and impaired in asexual development. Our results suggest a dual phosphorylation-dependent DenA/DEN1 stability control with stabilizing and destabilizing modifications and physical interaction partner proteins which function as control points in the nucleus and the cytoplasm. PMID:27010942

  14. Vera Peters and the curability of Hodgkin disease

    PubMed Central

    Cowan, D.H.

    2008-01-01

    The middle of the 20th century hailed the realization that patients with Hodgkin disease could be cured. Through the groundbreaking work of Vera Peters, patients with a localized form of the disorder, previously thought to be incurable, were shown to be cured by extended-field radiotherapy. This important observation, although not immediately accepted, opened the minds of physicians to take more positive investigative and therapeutic approaches. Peters also introduced and championed the concept of tumour staging in Hodgkin disease and the use of prognostic factors in clinical decision-making. This novel approach led to high cure rates with radiotherapy in localized disease and provided a scientific basis for the subsequent use of chemotherapy in disseminated disease, resulting in a very high cure rate in patients with all stages of Hodgkin disease. PMID:19008994

  15. VAN method lacks validity

    NASA Astrophysics Data System (ADS)

    Jackson, David D.; Kagan, Yan Y.

    Varotsos and colleagues (the VAN group) claim to have successfully predicted many earthquakes in Greece. Several authors have refuted these claims, as reported in the May 27,1996, special issue of Geophysical Research Letters and a recent book, A Critical Review of VAN [Lighthill 1996]. Nevertheless, the myth persists. Here we summarize why the VAN group's claims lack validity.The VAN group observes electrical potential differences that they call “seismic electric signals” (SES) weeks before and hundreds of kilometers away from some earthquakes, claiming that SES are somehow premonitory. This would require that increases in stress or decreases in strength cause the electrical variations, or that some regional process first causes the electrical signals and then helps trigger the earthquakes. Here we adopt their notation SES to refer to the electrical variations, without accepting any link to the quakes.

  16. Van Gogh Sun

    NASA Video Gallery

    Nicholeen Viall, a solar scientist at NASA's Goddard Space Flight Center creates images of the sun reminiscent of Van Gogh, but it's science, not art. The color of each pixel contains a wealth of i...

  17. Dr. Peter Emil Becker and the Third Reich.

    PubMed

    Hill, Frank

    2013-08-01

    In 1985 the physician after whom Becker Muscular Dystrophy is named, German neurologist Dr. Peter Emil Becker (1908-2000), published an autobiographical article in the American Journal of Medical Genetics in which he disavowed any association with the Nazi Party. A closer look at the evidence, however, suggests otherwise. Review of war records and related sources raise concern for Dr. Becker's affiliation with the Nazi Party and his contributions to its ideology. PMID:23813666

  18. A tribute to Peter A. Rona: A Russian Perspective

    NASA Astrophysics Data System (ADS)

    Sagalevich, Anatoly; Lutz, Richard A.

    2015-11-01

    In July 1985 Peter Rona led a cruise of the National Oceanic and Atmospheric Administration (NOAA) ship Researcher as part of the NOAA Vents Program and discovered, for the first time, black smokers, massive sulfide deposits and vent biota in the Atlantic Ocean. The site of the venting phenomena was the Trans-Atlantic Geotraverse (TAG) Hydrothermal Field on the east wall of the rift valley of the Mid-Atlantic Ridge at 26°08‧N; 44°50‧W (Rona, 1985; Rona et al., 1986). In 1986, Peter and an international research team carried out multidisciplnary investigations of both active and inactive hydrothermal zones of the TAG field using the R/V Atlantis and DSV Alvin, discovering two new species of shrimp (Rimicaris exoculata and Chorocaris chacei) (Williams and Rona, 1986) and a hexagonal-shaped form (Paleodictyon nodosum) thought to be extinct (Rona et al., 2009). In 1991 a Russian crew aboard the R/V Akademik Mstislav Keldysh, with two deep-diving, human-occupied submersibles (Mir-1 and Mir-2) (Fig. 1), had the honor of having Peter Rona and a Canadian IMAX film crew from the Stephen Low Company on board to visit the TAG hydrothermal vent field. This was the first of many deep-sea interactions between Russian deep-sea scientists and their colleagues from both the U.S. and Canada. This expedition to the TAG site was part of a major Russian undersea program aimed at exploring extreme deep-sea environments; between 1988 and 2005, the Mir submersibles visited hydrothermal vents and cold seep areas in 20 deep-sea regions throughout the world's oceans (Sagalevich, 2002). Images of several of these areas (the TAG, Snake Pit, Lost City and 9°50‧N vent fields) were obtained using an IMAX camera system emplaced for the first time within the spheres of the Mir submersibles and DSV Alvin in conjunction with the filming of science documentaries (e.g., "Volcanoes of the Deep Sea") produced by the Stephen Low Company in conjunction with Emory Kristof of National Geographic and

  19. Peter Bergmann:The Education of a Physicist

    NASA Astrophysics Data System (ADS)

    Halpern, Paul

    2005-12-01

    I explore the early life and contributions of Peter Bergmann (1915 2002), focusing on his family background, education, and ideas. I examine how Bergmann’s formative years were shaped by the outspoken influence of his mother, a leading educational reformer; the distinguished reputation of his father, a renowned materials chemist; and his cherished hope of working with Albert Einstein (1879 1955), to whom he eventually became an assistant. Inspired by these and other notable thinkers, Bergmann became an exemplary organizer, educator, and mentor in the fields of general relativity and quantum gravity.

  20. Van der Waals Forces

    NASA Astrophysics Data System (ADS)

    Parsegian, V. Adrian

    2006-03-01

    This should prove to be the definitive work explaining van der Waals forces, how to calculate them and take account of their impact under any circumstances and conditions. These weak intermolecular forces are of truly pervasive impact, and biologists, chemists, physicists and engineers will profit greatly from the thorough grounding in these fundamental forces that this book offers. Parsegian has organized his book at three successive levels of mathematical sophistication, to satisfy the needs and interests of readers at all levels of preparation. The Prelude and Level 1 are intended to give everyone an overview in words and pictures of the modern theory of van der Waals forces. Level 2 gives the formulae and a wide range of algorithms to let readers compute the van der Waals forces under virtually any physical or physiological conditions. Level 3 offers a rigorous basic formulation of the theory. Author is among the most highly respected biophysicists Van der Waals forces are significant for a wide range of questions and problems in the life sciences, chemistry, physics, and engineering, ranging up to the macro level No other book that develops the subject vigorously, and this book also makes the subject intuitively accessible to students who had not previously been mathematically sophisticated enough to calculate them

  1. Pythagoras Meets Van Hiele.

    ERIC Educational Resources Information Center

    Flores, Alfinio

    1993-01-01

    Develops the Pythagorean Theorem in the context of the Van Hiele levels by presenting activities appropriate for each level. Activities point to preparatory development (level 0), give 3 different versions of Euclid's proof (levels 1, 2, and 3), give some generalizations of the theorem (level 3), and explore the Pythagorean relationship in other…

  2. Van Gogh's Sunflowers

    ERIC Educational Resources Information Center

    Daddino, Michelle

    2010-01-01

    In this article, the author describes an art project wherein kindergarten students painted sunflowers. These beautiful and colorful sunflowers were inspired by the book "Camille and the Sunflowers" by Laurence Anholt, which does an amazing job of introducing young children to the art and life of Vincent van Gogh.

  3. Polar bear maternity denning in the Beaufort Sea

    USGS Publications Warehouse

    Amstrup, S.; Gardner, C.

    1994-01-01

    The distribution of polar bears (Ursus maritimus) is circumpolar in the NOrthern Hemisphere, but known locations of maternal dens are concentrated in relatively few, widely scattered locations. Denning is either uncommon or unknown within gaps. To understand effects of industrial development and propose increases in hunting, the temporal and spatial distribution of denning in the Beaufort Sea must be known. We caputred and radiocollared polar bears between 1981 and 1991 and determined tht denning in the Beaufort Sea region was sufficient to account for the estimated population there. Of 90 dend, 48 were on drifting pack ice, 38 on land, and 4 on land-fast ice. The portions of dens on land was higher (P= 0.029) in later compared with earlier years of the study. Bears denning on pack ice drifting as far as 997 km (x=385km) while in dens. there was no difference in cun production by bears denning on land and pack ice (P =0.66). Mean entry and exit dates were 11 November and 5 April for land dens and 22 November and 26 March for pack-ice dens. Female polar bears captured in the Beaufort Sea appeared to be isolated from those caught eat of Cape Bathurst in Canada. Of 35 polar bears that denned along the mainland coast of Alaska and Canada 80% denned between 137 00'W snf 146 59'W. Bears followed to >1 den did not reuse sites and consecutive dens were 20-1,304 km apart. However radio-collared bears are largely faithful to substrate (pack-ice, land, and land-fast ice) and the general geographic area of previous dens. Bears denning on land may be vunerable to human activities such as hunting and industrial development. However, predictable denning chronology and alck of site fidelity indicate that many potential impacts on denning polar bears could be mitigated.

  4. Dragons' Den: promoting healthcare research and innovation.

    PubMed

    Mazhindu, Deborah; Gregory, Siobhan

    2015-07-01

    The changing health and social care landscape, and, in particular, the financial challenges affecting the NHS, can present difficulties for staff looking for funding to support innovation and new ways of working. One method of competitive tendering that is becoming more accepted as a way of allocating funds, encouraging staff engagement and developing innovation for research is a format based the BBC television series, Dragons' Den. This article describes how Hounslow and Richmond Community Healthcare NHS Trust, London, has developed a 'Dragons' Den initiative' of annual competitive research funding allocation to ensure that some of the most dynamic practice in the trust is captured. PMID:26135194

  5. John P. Peters and the committee of 430 physicians.

    PubMed

    Lundberg, George D

    2002-01-01

    John Peters and his committee had a few basic goals. One was that local, state, and federal governments needed to provide money to construct facilities, support medical research and education, and care for the poor. And they wanted experts to call the shots. Over time, Peters and the committee got what they wanted for the most part: Hill-Burton money for building the hospitals, the rise of the National Institutes of Health, Medicare, Medicaid, a Veterans Administration system, and new and expanded medical schools. The experts calling the shots included David Kessler at the Food and Drug Administration and Surgeon General C. Everett Koop. In the halcyon days of American health system reform, back in 1993, Yale's Paul Beeson wrote about the Committee of 430 Physicians and its goals in the Pharos of Alpha Omega Alpha. Beeson was optimistic and he quoted from my 1991 JAMA health system reform editorial as a sharp contrast to what Fishbein had written - although coincidentally, we both quote Lincoln. My editorial began, "'with malice toward none, with charity for all...' so spoke Abraham Lincoln in his second inaugural address recognizing that he had no political consensus regarding either the constitutionality of states seceding or the morality of slavery being abolished. Nonetheless, he knew what was right and was able, through persuasive, often inspiring rhetoric, to conclude a bloody and decisive Civil War and constitute the foundation for this great republic.... Yet access to basic medical care for all of our inhabitants is still not a reality in this country. There are many reasons for this, not the least of which is a long-standing, systematic, institutionalized racial discrimination.... An aura of inevitablitiy is upon us. It is not acceptable morally, ethically, or economically for so many of our people to be medically uninsured or seriously underinsured. We can solve this problem. We have the knowledge and the resources, the skills, the time, and the moral

  6. Vision and Elusiveness in Philosophy of Education: R. S. Peters on the Legacy of Michael Oakeshott

    ERIC Educational Resources Information Center

    Williams, Kevin

    2009-01-01

    Despite his elusiveness on important issues, there is much in Michael Oakeshott's educational vision that Richard Peters quite rightly wishes to endorse. The main aim of this essay is, however, to consider Peters' justifiable critique of three features of Oakeshott's work. These are (1) the rigidity of his distinction between vocational and…

  7. Reflections on Peters' View of the Nature and Purpose of Work in Philosophy of Education

    ERIC Educational Resources Information Center

    Aspin, D. N.

    2013-01-01

    In this article I describe the analytic approach adopted by Peters, his colleagues and followers of the "London line" in the 1960s and 1970s and argue that, even in those times, other approaches to philosophy of education were being valued and practised. I show that Peters and his colleagues later became aware of the need for philosophy of…

  8. The Future of the Digital Library: An Interview with Tom Peters

    ERIC Educational Resources Information Center

    Morrison, James L.; Peters, Tom

    2005-01-01

    This article presents an interview with Tom Peters, an academic librarian and founder of TAP Information Services, a firm that provides consulting services to libraries and other organizations in the information industry. Peters also serves as a consultant to LibraryCity, an ambitious project that seeks to make thousands of e-books in easy-to-use…

  9. The "Physically Educated" Person: Physical Education in the Philosophy of Reid, Peters and Aristotle

    ERIC Educational Resources Information Center

    MacAllister, James

    2013-01-01

    This article will derive a definition and account of the physically educated person, through an examination of the philosophy of Andrew Reid, Richard Peters and Aristotle. Initially, Reid's interpretation of Peters' views about the educational significance of practical knowledge (and physical education) will be considered. While it will…

  10. Ripples from a Passing Ship: Memories; and a Legacy of Richard Peters

    ERIC Educational Resources Information Center

    Harris, Kevin

    2013-01-01

    This paper outlines aspects and dimensions of my "relationship" with Richard Peters from 1966 onward. The underlying suggestion is that, while Peters' contribution to philosophy of education was undeniably of major proportions, both that contribution and his legacy are institutional rather than substantive. (Contains 15 notes.)

  11. Otto Peters on Distance Education: The Industrialization of Teaching and Learning. Routledge Studies in Distance Education.

    ERIC Educational Resources Information Center

    Keegan, Desmond, Ed.

    This book contains new and previously published translations of 11 essays and articles about the industrialization of teaching and learning in distance education that were originally published in German by Otto Peters between 1965 and 1993. A "Preface" (Desmond Keegan) and an introduction placing Peters' writings in their historical context begin…

  12. STS-81 Mission Specialist Peter Wisoff suits up

    NASA Technical Reports Server (NTRS)

    1997-01-01

    STS-81 Mission Specialist Peter J. K. 'Jeff' Wisoff prepares for the fifth Shuttle- Mir docking as he waits in the Operations and Checkout (O&C) Building for the operation to fit him into his launch/entry suit to be completed. He conducted a spacewalk on his on his first Shuttle mission, STS- 57 and holds a doctorate degree in applied physics with an emphasis on lasers and semiconductor materials. He and five crew members will shortly depart the O&C and head for Launch Pad 39B, where the Space Shuttle Atlantis will lift off during a 7-minute window that opens at 4:27 a.m. EST, January 12.

  13. [Peter of Abano, the 'Conciliator' between magic and science].

    PubMed

    Federici Vescovini, Graziella

    2008-01-01

    Peter of Abano is a personage belonging to history as well as to legend. In this analysis his historical physiognomy of scientist and physician is reconstructed on the basis of a better knowledge of his works in medicine and astronomy (now edited), a discipline, the latest one, in which he excelled in Medieval scientific context (The Lucidator dubitabilium astronomiae (astrologiae) can be read in the critical edition by G. Federici Vescovini, Padova, Esedra, 1992). He opposed extreme position in all fields, by styling himself 'Conciliator' of opposed tendencies. He often reconfirmed a rational concept of medicine and astronomy, which dispelled any demoniac and magic features, against the fanciful legend elaborated during the following centuries. PMID:19831246

  14. A rare presentation of multiple dens invaginatus in maxillary dentition

    PubMed Central

    Purani, Jigar M; Purani, Hiral J

    2014-01-01

    Dens invaginatus is a developmental disturbance of the tooth and usually occurs in the maxillary lateral incisor of permanent dentition. In this article, a rare case of dens invaginatus affecting multiple permanent maxillary teeth is described. PMID:25085944

  15. Obituary: James Alfred Van Allen, 1914-2006

    NASA Astrophysics Data System (ADS)

    Ludwig, George H.; McIlwain, Carl Edwin

    2006-12-01

    new Physics and Astronomy building was completed in 1964 (rechristened in 1982, appropriately, as Van Allen Hall), he set up his private working room apart from his departmental office in a large, soon-cluttered, corner office on the seventh floor. That room became the center of his activity in 1985, when he retired as Department Head and active teacher. There, through his retirement years and until shortly before his death, he continued his roles as researcher, advisor, and mentor, serving at times as Professor Emeritus, Carver Professor of Physics, and Regent Distinguished Professor. Van Allen maintained membership in over a dozen professional organizations and received over a dozen Honorary ScD degrees. His additional awards and other distinct forms of recognition are far too numerous to list here, but include AAS's Gerard P. Kuiper Prize, the Crafoord Prize of the Royal Swedish Academy of Science, the National Medal of Science presented by U.S. President Reagan, the National Science Foundation's Vannevar Bush Award, NASA's Lifetime Achievement Award, the 2006 Smithsonian National Air and Space Museum Lifetime Achievement Trophy, the Gold Medal of the Royal Astronomy Society, AGU's John A. Fleming Award and William Bowie Medal, and the Abelson Prize by the American Association for the Advancement of Science. In addition to those many public acknowledgements of his prodigious contributions, James A. Van Allen will be fondly remembered by his many students, who now populate the entire realm of modern space research. He is survived by his wife, Abigail Fithian Halsey II Van Allen, and his five children, Cynthia Van Allen Schaffner, Dr. Margot Van Allen Cairns, Sarah Van Allen Trimble, Thomas Halsey Van Allen, and Peter C. Van Allen.

  16. van der Waals torque

    NASA Astrophysics Data System (ADS)

    Esquivel-Sirvent, Raul; Schatz, George

    2014-03-01

    The theory of generalized van der Waals forces by Lifshtz when applied to optically anisotropic media predicts the existence of a torque. In this work we present a theoretical calculation of the van der Waals torque for two systems. First we consider two isotropic parallel plates where the anisotropy is induced using an external magnetic field. The anisotropy will in turn induce a torque. As a case study we consider III-IV semiconductors such as InSb that can support magneto plasmons. The calculations of the torque are done in the Voigt configuration, that occurs when the magnetic field is parallel to the surface of the slabs. The change in the dielectric function as the magnetic field increases has the effect of decreasing the van der Waals force and increasing the torque. Thus, the external magnetic field is used to tune both the force and torque. The second example we present is the use of the torque in the non retarded regime to align arrays of nano particle slabs. The torque is calculated within Barash and Ginzburg formalism in the nonretarded limit, and is quantified by the introduction of a Hamaker torque constant. Calculations are conducted between anisotropic slabs of materials including BaTiO3 and arrays of Ag nano particles. Depending on the shape and arrangement of the Ag nano particles the effective dielectric function of the array can be tuned as to make it more or less anisotropic. We show how this torque can be used in self assembly of arrays of nano particles. ref. R. Esquivel-Sirvent, G. C. Schatz, Phys. Chem C, 117, 5492 (2013). partial support from DGAPA-UNAM.

  17. 1988 Horton Medal presented to Peter S. Eagleson

    NASA Astrophysics Data System (ADS)

    Rodriguez-Iturbe, Ignacio; Eagleson, Peter S.

    It is indeed a great honor for me, and also a great pleasure, to present to you the 1988 recipient of the Robert E. Horton Medal, Peter S. Eagleson. Shortly after it became public that Pete was the winner of this year's medal, I commented to my wife that, although I had never given a citation for an AGU medalist, this was one I would really love to give. The reason is simple: there is no one in the world who better represents the standards of excellence that a hydrologist hopes to achieve and that hydrologists hope our discipline will attain than Peter Eagleson.Pete did not start his research career in hydrology. In fact, his Ph.D. thesis in 1956 and his research up to 1965 were mainly in the field of sediment sorting and transport by waves on beaches. During this period he also investigated problems related to flow-induced vibrations of plates. His research in these areas was extremely successful, producing three chapters in books and about 20 journal papers in addition to many technical reports and journal discussions. Indeed, Pete had made his mark in wave theory and sediment transport, but it was good fortune for our field that starting about 1964 his interest in hydrology overcame all his past experience and assured a reputation in the waves and sediment field, and thus he embarked on a new adventure—bringing into hydrology the scientific rigor that existed in more academically established disciplines. With his strong fluid mechanics background—he still teaches that subject to undergraduates at MIT—Pete was ideally suited to lead the field toward new problems and also toward new approaches to old problems . . . and this he did indeed! Just in 1967 he and his students published six papers, most of them in Water Resources Research, which had a strong, an almost immediate impact on the field of hydrology. Here was somebody who was tackling the modeling of overland flow with the scientific standards of fluid mechanics. At the same time, finally somebody had

  18. Defending commercial surrogate motherhood against Van Niekerk and Van Zyl.

    PubMed Central

    McLachlan, H V

    1997-01-01

    The arguments of Van Niekerk and Van Zyl that, on the grounds that it involves an inappropriate commodification and alienation of women's labour, commercial surrogate motherhood (CSM) is morally suspect are discussed and considered to be defective. In addition, doubt is cast on the notion that CSM should be illegal. PMID:9451602

  19. Analog of the Peter-Weyl expansion for Lorentz group

    NASA Astrophysics Data System (ADS)

    Perlov, Leonid

    2015-11-01

    The expansion of a square integrable function on SL(2, C) into the sum of the principal series matrix coefficients with the specially selected representation parameters was recently used in the Loop Quantum Gravity [C. Rovelli and F. Vidotto, Covariant Loop Quantum Gravity: An Elementary Introduction to Quantum Gravity and Spinfoam Theory (Cambridge University Press, Cambridge, 2014) and C. Rovelli, Classical Quantum Gravity 28(11), 114005 (2011)]. In this paper, we prove that the sum used originally in the Loop Quantum Gravity: ∑ j = 0 ∞ ∑ |m| ≤ j ∑ |n| ≤ j Dj m , j n ( j , τ j ) ( g ) , where j, m, n ∈ Z, τ ∈ C is convergent to a function on SL(2, C); however, the limit is not a square integrable function; therefore, such sums cannot be used for the Peter-Weyl like expansion. We propose the alternative expansion and prove that for each fixed m: ∑ j = m ∞ D j m , j m ( j , τ j ) ( g ) is convergent and that the limit is a square integrable function on SL(2, C). We then prove the analog of the Peter-Weyl expansion: any ψ(g) ∈ L2(SL(2, C)) can be decomposed into the sum: ψ ( g ) = ∑ j = m ∞ j 2 ( 1 + τ 2 ) c j m m D j m , j m ( j , τ j ) ( g ) , with the Fourier coefficients c j m m = ∫ S L ( 2 , C ) ψ ( g ) Dj m , j m j , τ j ( g ) ¯ d g , g ∈ SL(2, C), τ ∈ C, τ ≠ i, - i, j, m ∈ Z, m is fixed. We also prove convergence of the sums ∑ j = |p| ∞ ∑ |m| ≤ j ∑ |n| ≤ j dp m /j 2 Dj m , j n ( j , τ j ) ( g ) , where d|p| m /j 2 = ( j + 1 ) /1 2 ∫ S U ( 2 ) ϕ ( u ) D|p| m /j 2 ( u ) ¯ d u is ϕ(u)'s Fourier transform and p, j, m, n ∈ Z, τ ∈ C, u ∈ SU(2), g ∈ SL(2, C), thus establishing the map between the square integrable functions on SU(2) and the space of the functions on SL(2, C). Such maps were first used in Rovelli [Class. Quant. Grav. 28, 11 (2011)].

  20. Dens Evaginatus: A Problem-Based Approach

    PubMed Central

    Ayer, A.; Vikram, M.; Suwal, P.

    2015-01-01

    Dens evaginatus is an uncommon developmental anomaly of human dentition characterized by the presence of tubercle on the occlusal surface of mandibular premolars and lingual surface of anterior teeth. Due to occlusal trauma this tubercle tends to fracture thus exposing the pathway to the pulp chamber of teeth. This case report is about the presentation of dens evaginatus in mandibular premolars bilaterally; among them tooth 44 was associated with chronic apical periodontitis. Fractured tubercle of three premolars was sealed with composite resin. Root canal treatment was performed with tooth 44. Routine endodontic treatment did not result in remission of infection. Therefore, culture and sensitivity tests were performed to identify the cause and modify treatment plan accordingly. Triple antibiotic paste was used as an intracanal medicament to disinfect the root canal that resulted in remission of infection. PMID:26779353

  1. Cato Guldberg and Peter Waage, the history of the Law of Mass Action, and its relevance to clinical pharmacology.

    PubMed

    Ferner, Robin E; Aronson, Jeffrey K

    2016-01-01

    We have traced the historical link between the Law of Mass Action and clinical pharmacology. The Law evolved from the work of the French chemist Claude Louis Berthollet, was first formulated by Cato Guldberg and Peter Waage in 1864 and later clarified by the Dutch chemist Jacobus van 't Hoff in 1877. It has profoundly influenced our qualitative and quantitative understanding of a number of physiological and pharmacological phenomena. According to the Law of Mass Action, the velocity of a chemical reaction depends on the concentrations of the reactants. At equilibrium the concentrations of the chemicals involved bear a constant relation to each other, described by the equilibrium constant, K. The Law of Mass Action is relevant to various physiological and pharmacological concepts, including concentration-effect curves, dose-response curves, and ligand-receptor binding curves, all of which are important in describing the pharmacological actions of medications, the Langmuir adsorption isotherm, which describes the binding of medications to proteins, activation curves for transmembrane ion transport, enzyme inhibition and the Henderson-Hasselbalch equation, which describes the relation between pH, as a measure of acidity and the concentrations of the contributory acids and bases. Guldberg and Waage recognized the importance of dynamic equilibrium, while others failed to do so. Their ideas, over 150 years old, are embedded in and still relevant to clinical pharmacology. Here we explain the ideas and in a subsequent paper show how they are relevant to understanding adverse drug reactions. PMID:26174880

  2. Peter Agre, 2003 Nobel Prize winner in chemistry.

    PubMed

    Knepper, Mark A; Nielsen, Soren

    2004-04-01

    Peter C. Agre, an American Society of Nephrology member, is the recipient of the 2003 Nobel Prize in Chemistry for his discovery of the aquaporin water channels. The function of many cells requires that water move rapidly into and out of them. There was only indirect evidence that proteinaceous channels provide this vital activity until Agre and colleagues purified aquaporin-1 from human erythrocytes and reported its cDNA sequence. They proved that aquaporin-1 is a specific water channel by cRNA expression studies in Xenopus oocytes and by functional reconstitution of transport activity in liposomes after the incorporation of the purified protein. These findings sparked a veritable explosion of work that affects several long-standing areas of investigation such as the biophysics of water permeation across cell membranes, the structural biology of integral membrane proteins, the physiology of fluid transport in the kidney and other organs, and the pathophysiological basis of inherited and acquired disorders of water balance. Agre's discovery of the first water channel has spurred a revolution in animal and plant physiology and in medicine. PMID:15034115

  3. Peter Howard Elworthy (1933-1995): a biographical note.

    PubMed

    Florence, A T

    1997-06-01

    Peter Elworthy had a considerable influence on pharmaceutical science, education and practice, in the UK. He died in December 1995 at the early age of 62, but he had retired from full time academic work from his post as Professor of Pharmacy and Head of the Department of Pharmacy in the University of Manchester twelve years earlier. Concerned about his health but also not a little disillusioned by the multiple pressures placed even then on senior academics, he foresaw the era of cuts and the central oversight and restrictions. His heart was elsewhere. In his 1976 Harrison Memorial Lecture (reproduced in this issue) he said: "Looking back, I have the feeling of having been very lucky. 'Much have I travell'd in the realms of gold, and many goodly states and kingdoms seen.' My main interest has been in the phenomenon of micellization. The subject has been of absorbing interest, and continually shows new bright facets which lead to new scientific advances. Travelling in the realms of gold has nothing to do with gold, but to me it means travelling in sunlight, which illuminates things brightly, and makes visible new facts, which have been invisible before. Occasionally dark clouds form; they are the disappointments and frustrations, but we need them in order to be able to recognize the sunlight by contrast." PMID:9330193

  4. Becoming a peter pan: omnipotence, dependency and the Ferenczian child.

    PubMed

    Bar-Haim, Shaul

    2015-03-01

    The aim of this paper is to provide a short history of the changes in Ferenczi's concept of early childhood, during the two decade period, 1913-1932. Initially, Ferenczi mainly emphasized children's feelings of omnipotence, which enable them to perceive themselves as strong, independent and capable human beings. By the mid-1920s, however, he felt that his earlier work did not give a good account of what comes after the stage of omnipotence, and that it did not adequately describe the difficulties in the transition from pleasure to reality principles. However, in his Clinical Diary, Ferenczi became fully aware of how fragile and insecure children are, and therefore how dangerous-yet necessary-it is for them to abandon the "stage of omnipotence" and to gain a "sense of reality". For Ferenczi, traumatized children are children who had not been loved in their early childhood, and therefore could not develop the capacity to make the journey from pleasure principle to that of reality. It will be suggested that a paradigmatic example for this kind of child is Peter Pan. PMID:25720781

  5. Peters anomaly in a red kangaroo (Macropus rufus).

    PubMed

    Suedmeyer, Wm Kirk; Pearce, Jacqueline; Persky, Meredith; Houck, Marlys L

    2014-09-01

    A 10-mo-old female red kangaroo (Macropus rufus) presented with a unilateral congenital corneal opacity OD. Complete ophthalmic examination revealed a shallow anterior chamber and a focal area of corneal edema with multiple persistent pupillary membranes extending from the iris colarette to the corneal endothelium adjacent to the edematous area of cornea. High-resolution B-scan ultrasound of the anterior segment showed an area consistent with thinning of Descemet's membrane in the area of corneal edema. Ophthalmic examination and ultrasound findings are consistent with a diagnosis of Peters anomaly, a form of anterior segment dysgenesis. An electroretinogram performed on the affected animal did not reveal any specific abnormalities. Karyotype analyses revealed a normal diploid number (2n = 20, -XX), with an abnormal pericentric inversion in the second largest chromosomal pair. The kangaroo exhibits mild compensated vision deficits in the affected eye. The maternal and paternal adult pairing has been discontinued in an effort to prevent future offspring anomalies. PMID:25314851

  6. Romantic Resonances in the Rhetoric of Peter Elbow's "Writing Without Teachers."

    ERIC Educational Resources Information Center

    Yager, Kristi

    1996-01-01

    Seeks to uncover the historical roots within English Romanticism of Peter Elbow's thinking in order to show the depth and complexity of his assumptions about writing. Implicitly refutes charges questioning the intellectual credibility of Elbow's work. (TB)

  7. Ellis van Creveld syndome.

    PubMed

    Ghanekar, Jaishree; Sangrampurkar, Sujata; Hulinaykar, Raman; Ahmer, Tariq

    2009-07-01

    Ellis-van Creveld syndrome (EVC) or chondroectodermal dysplasia is a rare autosomal recessive disorder. It is a tetrad of chondrodysplasia, ectodermal dysplasia, polydactyly, and congenital heart disease. In several case reports, dysplasia involving other organs has also been identified. The exact prevalence is unknown, but the syndrome seems more common among the Amish community. Many Indian cases have also been reported. This report describes a classical case of EVC syndrome in a 22 year old woman of Indian origin born of a consanginous marriage. The patient had chondrodysplasia of tubular bones resulting in disproportionate dwarfism, postaxial polydactyly, severely dystrophic nails, partially absent teeth, pectus excavatum with narrow chest, knock knees and AV canal defect. PMID:20329417

  8. 8q21.11 microdeletion in two patients with syndromic peters anomaly.

    PubMed

    Happ, Hannah; Schilter, Kala F; Weh, Eric; Reis, Linda M; Semina, Elena V

    2016-09-01

    Peters anomaly is a form of anterior segment dysgenesis characterized by central ocular opacity and corneo-lenticular adhesions. Isolated and syndromic Peters anomaly can be observed and demonstrate significant genetic heterogeneity. We report the identification of overlapping 8q21.11 deletions in two patients with syndromic Peters anomaly via whole exome sequencing and chromosomal microarray analyses. Microdeletions of 8q21.11 were recently reported in 10 patients with highly variable phenotypes involving craniofacial features, ptosis, intellectual disability, abnormalities of the hands/feet and other defects; sclerocornea and/or microphthalmia were reported in three cases. The two additional cases presented in this report expand the phenotypic spectrum of 8q21.11 microdeletions to include Peters anomaly (seen in both patients) and persistent primary dentition (seen in one patient with a larger deletion). The two novel deletions include the ZFHX4 and PEX2 genes, which were also affected in all three previous cases involving ocular anomalies. Screening of the remaining alleles of ZFHX4 and PEX2 did not identify any additional likely pathogenic variants in either patient, suggesting a dominant mechanism (haploinsufficiency) for the identified deletion. This report provides further insight into the phenotypes associated with 8q21.11 deletions and, for the first time, reports Peters anomaly as an additional ocular feature; screening for copy number variations of the 8q21.11 region should be considered in patients with Peters anomaly and related syndromic features. © 2016 Wiley Periodicals, Inc. PMID:27378168

  9. Sophus Peter Tromholt: an outstanding pioneer in auroral research

    NASA Astrophysics Data System (ADS)

    Moss, K.; Stauning, P.

    2012-03-01

    The Danish school teacher Sophus Peter Tromholt (1851-1896) was self-taught in physics, astronomy, and auroral sciences. Still, he was one of the brightest auroral researchers of the 19th century. He was the first scientist ever to organize and analyse correlated auroral observations over a wide area (entire Scandinavia) moving away from incomplete localized observations. Tromholt documented the relation between auroras and sunspots and demonstrated the daily, seasonal and solar cycle-related variations in high-latitude auroral occurrence frequencies. Thus, Tromholt was the first ever to deduce from auroral observations the variations associated with what is now known as the auroral oval termed so by Khorosheva (1962) and Feldstein (1963) more than 80 yr later. He made reliable and accurate estimates of the heights of auroras several decades before this important issue was finally settled through Størmer's brilliant photographic technique. In addition to his three major scientific works (Tromholt, 1880a, 1882a, and 1885a), he wrote numerous short science notes and made huge efforts to collect historical auroral observations (Tromholt, 1898). Furthermore, Tromholt wrote a large number of popular science articles in newspapers and journals and made lecture tours all over Scandinavia and Germany, contributing to enhance the public educational level and awareness. He devoted most of his life to auroral research but as a self-taught scientist, he received little acclaim within the contemporary academic scientific society. With his non-academic background, trained at a college of education - not a university - he was never offered a position at a university or a research institution. However, Sophus Tromholt was an outstanding pioneer in auroral research.

  10. Goiter in paintings by Rogier van der Weyden (1399-1464).

    PubMed

    Lazzeri, Davide; Pozzilli, Paolo; Zhang, Yi Xin; Persichetti, Paolo

    2015-05-01

    Figures affected by goiter were only sparsely depicted by Peter Paul Rubens and Albrecht Dürer among Flemish artists, because obvious goiter was not common in regions such as the Netherlands and Belgium. However, the recent observation of two figures with a goiter elegantly depicted by Rogier van der Weyden has raised our interest in this topic. When taking a close look at the paintings of this Flemish Renaissance painter, it is interesting to note that 16 portrayed subjects show an abnormal profile of the neck with swelling, suggestive of a presumptive medico-artistic diagnosis of goiter. Van der Weyden travelled to Italy where he soon acquired great fame and was second only to the other Flemish painter of the time, Jan Van Eyck. It is very likely that in Italy he had the opportunity to look at several female figures depicted with goiter, which may have influenced his paintings. Van der Weyden was appreciated because of his style to mix realistic details with idealized softened features to increase the beauty and appeal of his models. It is also likely that the integration of the goiter may have been part of the Renaissance tendency toward a more realistic and precise representation of subjects. The fact that in almost all cases the goiter was a low-to-moderate grade enlargement of the thyroid may confirm our speculation that perhaps the painter used the same model or the template derived from one model for subsequent paintings. PMID:25747746

  11. Denning behaviour of non-gravid wolves, Canis lupus

    USGS Publications Warehouse

    Mech, L.D.; Phillips, M.K.; Smith, D.W.; Kreeger, T.J.

    1996-01-01

    Wild wolves (Canis lupus) that had produced pups in earlier years but were not currently pregnant, and ovariectomized captive wolves, dug dens during and after the whelping season even though they produced no pups. These observations suggest that den digging is not a function of pregnancy or of ovarian estrogen or progesterone. We hypothesize that increasing prolactin in spring elicits or mediates den-digging behavior.

  12. Stirling Powered Van Progam overview

    NASA Technical Reports Server (NTRS)

    Shaltens, R. K.

    1986-01-01

    The Stirling Powered Van Program (SPVP) is a multiyear, multiphase program to evaluate the automotive Stirling engine (ASE) in Air Force vans under realistic conditions. The objective of the SPVP is to transfer to manufacturer and end user(s) (i.e., on the path to commercialization) the second-generation Mod 2 ASE upon completion of the Automotive Stirling Engine Program in 1987. In order to meet this objective, the SPVP must establish Stirling performance, integrity, reliability, durability and maintainability. The ASE program background leading to the van program is reviewed and plans for evaluating the kinematic Stirling engine in Air Force vans examined. Also discussed are the NASA technology transfers to industry that have been accomplished and those which are currently being developed.

  13. SLAM in a van

    NASA Astrophysics Data System (ADS)

    Binns, Lewis A.; Valachis, Dimitris; Anderson, Sean; Gough, David W.; Nicholson, David; Greenway, Phil

    2002-07-01

    We have developed techniques for Simultaneous Localization and Map Building based on the augmented state Kalman filter, and demonstrated this in real time using laboratory robots. Here we report the results of experiments conducted out doors in an unstructured, unknown, representative environment, using a van equipped with a laser range finder for sensing the external environment, and GPS to provide an estimate of ground truth. The goal is simultaneously to build a map of an unknown environment and to use that map to navigate a vehicle that otherwise would have no way of knowing its location. In this paper we describe the system architecture, the nature of the experimental set up, and the results obtained. These are compared with the estimated ground truth. We show that SLAM is both feasible and useful in real environments. In particular, we explore its repeatability and accuracy, and discuss some practical implementation issues. Finally, we look at the way forward for a real implementation on ground and air vehicles operating in very demanding, harsh environments.

  14. Professor Peter Choyce: an early pioneer of intraocular lenses and corneal/refractive surgery.

    PubMed

    Pandey, Suresh K; Apple, David J

    2005-06-01

    Professor Peter Choyce, FRCS, DOMS, MS, was one of the pioneers of intraocular lens implant surgery. He developed an interest in artificial lens implantation following cataract surgery, a procedure that was widely criticized by the ophthalmic establishment in the UK, Europe, North America and other countries. Owing to the opposition to the intraocular lenses, Peter Choyce together with Sir Harold Ridley co-founded the International Intraocular Implant Club in 1966, which was responsible for the gradual acceptance of artificial lens implantation. Peter Choyce developed several models of intraocular lens, but did not patent the majority of them. The Choyce Mark IX, manufactured by Rayner Intraocular Lenses, became the first US Food and Drug Administration-approved intraocular lens in 1981. A review of Peter Choyce's record confirms a significant number of original innovations in the field of anterior segment surgery, including many procedures taken for granted today, but not associated with his name. These include early work on both kerato- and intraocular lens-refractive procedures, keratoprosthesis, pioneering paediatric implant procedures and others. Unfortunately his tenacious adherence to anterior chamber lens technology, while in general clinically sound, caused many to question his influence and hence he remained poorly understood even until after his death. He passed away on 8 August 2001 after a long fight with colon cancer. In this article, we provide evidence and elaborate Peter Choyce's accomplishments, which places him as one of the most innovative ophthalmologist in his surgical field in the twentieth century. PMID:15932534

  15. View east along Wolf Den Road showing residences on the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View east along Wolf Den Road showing residences on the north side of the road - Brooklyn Green, North Green, South Green, & West Green, parts of Brown Road, Canterbury Road (Route 169), Hartford Road (Route 6), Hyde Road, Pomfret Road (Route 169), Prince Hill Road, Providence Road (Route 6), Wauregan Road (Routes 169 & 205), & Wolf Den Road, Brooklyn, Windham County, CT

  16. View northwest along Wolf Den Road showing residences on the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View northwest along Wolf Den Road showing residences on the north side of the road - Brooklyn Green, North Green, South Green, & West Green, parts of Brown Road, Canterbury Road (Route 169), Hartford Road (Route 6), Hyde Road, Pomfret Road (Route 169), Prince Hill Road, Providence Road (Route 6), Wauregan Road (Routes 169 & 205), & Wolf Den Road, Brooklyn, Windham County, CT

  17. Dens in dente in a six year old doberman pinscher.

    PubMed

    DeForge, D H

    1992-09-01

    Developmental abnormalities of tooth shape and form are rare. Identification of dens in dente is made by radiographic and clinical examination. Pulpitis, pulp necrosis and periapical inflammation can be associated with this abnormality. The tooth should be evaluated for endodontic therapy. A review of the literature related to dens in dente is described with the findings in a doberman pinscher. PMID:1290603

  18. The 2009 Lindau Nobel Laureate Meeting: Peter Agre, Chemistry 2003.

    PubMed

    Agre, Peter

    2009-01-01

    Peter Agre, born in 1949 in Northfield Minnesota, shared the 2003 Nobel Prize in Chemistry with Roderick MacKinnon for his discovery of aquaporins, the channel proteins that allow water to cross the cell membrane. Agre's interest medicine was inspired by the humanitarian efforts of the Medical Missionary program run by the Norwegians of his home community in Minnesota. Hoping to provide new treatments for diseases affecting the poor, he joined a cholera laboratory during medical school at Johns Hopkins. He found that he enjoyed biomedical research, and continued his laboratory studies for an additional year after medical school. Agre completed his clinical training at Case Western Hospitals of Cleveland and the University of North Carolina, and returned to Johns Hopkins in 1981. There, his serendipitous discovery of aquaporins was made while pursuing the identity of the Rhesus (Rh) antigen. For a century, physiologists and biophysicists had been trying to understand the mechanism by which fluid passed across the cell's plasma membrane. Biophysical evidence indicated a limit to passive diffusion of water, suggesting the existence of another mechanism for water transport across the membrane. The putative "water channel," however, could not be identified. In 1988, while attempting to purify the 30 kDa Rh protein, Agre and colleagues began investigating a 28 kDa contaminant that they believed to be a proteolytic fragment of the Rh protein. Subsequent studies over the next 3-4 years revealed that the contaminant was a membrane-spanning oligomeric protein, unrelated to the Rh antigen, and that it was highly abundant in renal tubules and red blood cells. Still, they could not assign a function to it. The breakthrough came following a visit with his friend and former mentor John Parker. After Agre described the properties of the mysterious 28 kDa protein, Parker suggested that it might be the long-sought-after water channel. Agre and colleagues tested this idea by

  19. The 2009 Lindau Nobel Laureate Meeting: Peter Agre, Chemistry 2003

    PubMed Central

    Agre, Peter

    2009-01-01

    Peter Agre, born in 1949 in Northfield Minnesota, shared the 2003 Nobel Prize in Chemistry with Roderick MacKinnon for his discovery of aquaporins, the channel proteins that allow water to cross the cell membrane. Agre's interest medicine was inspired by the humanitarian efforts of the Medical Missionary program run by the Norwegians of his home community in Minnesota. Hoping to provide new treatments for diseases affecting the poor, he joined a cholera laboratory during medical school at Johns Hopkins. He found that he enjoyed biomedical research, and continued his laboratory studies for an additional year after medical school. Agre completed his clinical training at Case Western Hospitals of Cleveland and the University of North Carolina, and returned to Johns Hopkins in 1981. There, his serendipitous discovery of aquaporins was made while pursuing the identity of the Rhesus (Rh) antigen. For a century, physiologists and biophysicists had been trying to understand the mechanism by which fluid passed across the cell's plasma membrane. Biophysical evidence indicated a limit to passive diffusion of water, suggesting the existence of another mechanism for water transport across the membrane. The putative "water channel," however, could not be identified. In 1988, while attempting to purify the 30kDa Rh protein, Agre and colleagues began investigating a 28 kDa contaminant that they believed to be a proteolytic fragment of the Rh protein. Subsequent studies over the next 3-4 years revealed that the contaminant was a membrane-spanning oligomeric protein, unrelated to the Rh antigen, and that it was highly abundant in renal tubules and red blood cells. Still, they could not assign a function to it. The breakthrough came following a visit with his friend and former mentor John Parker. After Agre described the properties of the mysterious 28 kDa protein, Parker suggested that it might be the long-sought-after water channel. Agre and colleagues tested this idea by

  20. K istorii goroskopa Petra Velikogo %t On the history of horoscope of Peter the Great

    NASA Astrophysics Data System (ADS)

    Bronshtehn, V. A.

    In the first part of the paper the question is discussed if Simeon Polotsky (1629-1680), poet and teacher of children of the Russian tsar Alexei Mikhailovich, was also the author of the horoscope of his son, in the future - Russian emperor Peter the Great, born in 1672. The poems by Simeon Polotsky with astrological contents are analyzed. The conclusion is supported that he could be the author of Peter the Great horoscope. In the second part a recently found text of the horoscope of Peter the Great reconstructed in 1775 by Russian astronomer Andrei Lexell of the request of historian G. F. Miller is published and discussed. It is also compared with texts previously published (in 1842) by Russian historians Pogodin and Polevoi.

  1. [The 'van der Linden' retainer].

    PubMed

    van der Linden, F P

    2003-11-01

    Normally, only the anterior teeth have to be retained after an orthodontic treatment. For that purpose, a lingually bonded wire is preferred in the mandible and a removable plate in the maxilla. The design of the Van der Linden-retainer is based on theoretical considerations and secures rigid fixation of the six anterior teeth with solid anchorage in that region. A retention plate should not be used to move anterior teeth. However, with instant corrections small improvements can be realized. The fabrication and clinical use of the Van der Linden-retainer is explained and illustrated. PMID:14669487

  2. Theories of Power, Poverty, and Law: In Commemoration of the Contributions of Peter Bachrach--Empowerment and Poverty

    ERIC Educational Resources Information Center

    Levi, Margaret

    2010-01-01

    My subject is the way Peter Bachrach addressed the question of poverty. But given that I was his student and research assistant and that I am a political scientist largely because of him, it is impossible to resist a few words about the experience of being in his classrooms. Peter was an inspiring teacher of politics. The substantive content of…

  3. 75 FR 63533 - Gulf & Ohio Railways Holding Co., Inc., H. Peter Claussen and Linda C. Claussen-Continuance in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Surface Transportation Board Gulf & Ohio Railways Holding Co., Inc., H. Peter Claussen and Linda C... Co., Inc. (G&O), H. Peter Claussen and Linda C. Claussen (the Claussens), noncarriers, have filed...

  4. Interview with Peter McLaren, on His Work, on His Visit to Turkey and on Ongoing Popular Struggles

    ERIC Educational Resources Information Center

    Fassbinder, Samuel Day

    2013-01-01

    Peter McLaren is, as the back cover of his (2005) Capitalists & Conquerors: a critical pedagogy against empire says, "professor of urban education at the Graduate School of Education and Information Studies at the University of California, Los Angeles". Peter is also now a Distinguished Fellow in Critical Studies at Chapman…

  5. Is R. S. Peters' Way of Mentioning Women in His Texts Detrimental to Philosophy of Education? Some Considerations and Questions

    ERIC Educational Resources Information Center

    Lees, Helen E.

    2012-01-01

    Discussion in this article considers the unfortunate way R.S. Peters made mention of women when it was pertinent to his argumentation: portraying them, directly or indirectly, as abuse-able (murderable), deficient, aberrant, clueless and inconstant. It is argued that the high profile and esteem within which Peter's texts are held within philosophy…

  6. The Dramatic Methods of Hans van Dam.

    ERIC Educational Resources Information Center

    van de Water, Manon

    1994-01-01

    Interprets for the American reader the untranslated dramatic methods of Hans van Dam, a leading drama theorist in the Netherlands. Discusses the functions of drama as a method, closed dramatic methods, open dramatic methods, and applying van Dam's methods. (SR)

  7. An Unusual Case of Peters Plus Syndrome with Sexual Ambiguity and Absence of Mutations in the B3GALTL Gene

    PubMed Central

    Siala, Olfa; Belguith, Neila; Fakhfakh, Faiza

    2013-01-01

    Background Peters Plus syndrome (MIM 261540) is a rare autosomal recessive condition characterized by ocular defects (typically Peters anomaly) and other systemic major/minor abnormalities. Mutations in the B3GALTL gene encoding the β-1,3-glucosyltransferase have been found in virtually all patients with typical Peters Plus syndrome. Case Presentation We report here a female patient with severe manifestations of Peters Plus syndrome including facial dysmorphism and bilateral corneal opacity associated with left renal pyelo-calicial dilatation and sexual ambiguity. Total sequencing of the B3GALTL gene revealed no mutation in the patient. Conclusion To our knowledge, sexual ambiguity has not previously been reported in Peters Plus syndrome so far, and renal malformation is also apparently rare in the syndrome. PMID:24427506

  8. Dens evaginatus: case reports and review of the literature.

    PubMed

    Ponnambalam, Yoganathan; Love, Robert M

    2006-06-01

    Dens evaginatus is a developmental anomaly that produces a tubercle on the occlusal or palatal or lingual surfaces of teeth. The tubercle, which often contains pulp tissue, can cause occlusal interference, and pulpal pathology is a common sequel of attrition or fracture of the evagination. It affects a number of tooth types, but most commonly the premolar teeth of people of oriental ethnicity. Early diagnosis and management of dens evaginatus are important to maintain pulp vitality. This article describes three cases of dens evaginatus with different presentations. PMID:16773794

  9. Education, Philosophy and Politics: The Selected Works of Michael A. Peters. World Library of Educationalists

    ERIC Educational Resources Information Center

    Peters, Michael A.

    2012-01-01

    In the World Library of Educationalists series, international experts themselves compile career-long collections of what they judge to be their finest pieces--extracts from books, key articles, salient research findings, major theoretical and/practical contributions--so the world can read them in a single manageable volume. Michael A. Peters has…

  10. 14. Photocopy of a photographca. 1902taken by A.W. Peters showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photocopy of a photograph--ca. 1902--taken by A.W. Peters showing Eastwood and his party surveying for the Big Creek Project. The surveying party is visible in the upper right corner. Courtesy Mr. Charles Allan Whitney. - Little Rock Creek Dam, Little Rock Creek, Littlerock, Los Angeles County, CA

  11. Two Is the Beginning of the End: "Peter Pan" and the Doctrine of Reminiscence

    ERIC Educational Resources Information Center

    Hudson, Glenda A.

    2006-01-01

    This article considers J.M. Barrie's satirical treatment of the Platonic doctrine of reminiscence in "Peter Pan," and how Barrie's work both honors and undercuts it. It will first analyze the Platonic notion of the doctrine of reminiscence in Wordsworth's "Ode: Intimations of Immortality from Recollections of Early Childhood" (1807). It will then…

  12. An End to the Curious Social Construction of "Expressivism" and the Pragmatist Tradition of Peter Elbow.

    ERIC Educational Resources Information Center

    Jones, Donald C.

    Labeling Peter Elbow an "expressivist" is an ironic reduction of his multifaceted thought to a one-dimensional term at a time when postmodernism stresses heteroglossia. This paper outlines the recent history of "expressivism" to demonstrate its curious social construction. The paper then calls for an "end of expressivism," and this end refers not…

  13. Writing in the American Grain: Peter Elbow's and David Bartholomae's Emersonian Pedagogies of Empowerment.

    ERIC Educational Resources Information Center

    Wiley, Mark

    1990-01-01

    Argues that, although Peter Elbow's and David Bartholomae's pedagogies attempt in different ways to authorize students to write, both rely on the experience and resistance to language as the primary means of empowerment. Suggests that Elbow and Bartholomae must continually defer authority, keeping it suspended between experience and its…

  14. The Authority of Truth: Religion and the John Peter Zenger Case.

    ERIC Educational Resources Information Center

    Nord, David Paul

    An appreciation of the religious milieu of the John Peter Zenger libel case of 1735 can help explain the nature of the Zenger defense as prepared by Alexander Hamilton, the meaning of the jury's verdict, and the ambiguous legacy of the trial for freedom of expression in the United States. In essence, the case was a disputation on "truth" and on…

  15. Sandra Diane Knapp—Recipient of the 2008 Peter Raven Award

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Dr. Sandra Knapp, Curator at Natural History Museum in London, is the 2009 recipient of the Peter Raven Award. This award is provided each year by the American Society of Plant Taxonomists to a plant systematist who has made exceptional efforts at outreach to nonscientists. This publication summariz...

  16. Respectability and Relevance: Reflections on Richard Peters and Analytic Philosophy of Education

    ERIC Educational Resources Information Center

    Snook, Ivan

    2013-01-01

    I argue that, after Dewey, Peters was the first modern philosopher of education to write material (in English) that was both philosophically respectable and relevant to the day-to-day concerns of teachers. Since then, some philosophers of education have remained (more or less) relevant but not really respectable while others have "taken off into…

  17. Reason and Virtues: The Paradox of R. S. Peters on Moral Education

    ERIC Educational Resources Information Center

    Haydon, Graham

    2009-01-01

    This article examines the work of R. S. Peters on moral development and moral education, as represented in his papers collected under that name, pointing out that these writings have been relatively neglected. It approaches these writings through the lens of the "familiar story" that philosophical work on this topic switched during, roughly, the…

  18. Transformation and Education: The Voice of the Learner in Peters' Concept of Teaching

    ERIC Educational Resources Information Center

    English, Andrea

    2009-01-01

    On several occasions in his work, R. S. Peters identifies a difficulty inherent in teaching that underscores the complexity of this relationship: the teacher has the task of passing on knowledge while at the same time allowing knowledge that is passed on to be criticised and revised by the learner. This inquiry asks: first, how does Peters…

  19. The Place of Philosophy in the Training of Teachers: Peters Revisited

    ERIC Educational Resources Information Center

    Clark, John A.

    2013-01-01

    In 1964, Richard Peters examined the place of philosophy in the training of teachers. He considered three things: Why should philosophy of education be included in the training of teachers; What portion of philosophy of education should be included; How should philosophy be taught to those training to be teachers. This article explores the context…

  20. The Possibilities of Transformation: Critical Research and Peter McLaren

    ERIC Educational Resources Information Center

    Porfilio, Brad J.

    2006-01-01

    The purpose of this paper is to unveil how Peter McLaren's revolutionary brand of pedagogy, multiculturalism, and research colored my two-year qualitative research study, which unearthed twenty White female future teachers' experiences and perceptions in relationship to computing technology and male-centered computing culture. His ideas positioned…

  1. ADENOCARCINOMA OF THE RETINAL PIGMENT EPITHELIUM IN THE GUPPY POECILIA RETICULATA PETERS

    EPA Science Inventory

    A single case of adenocarcinoma of the retinal pigment epithelium occurred in a guppy, Poecilia reticulata Peters. his is the first such tumor reported from fishes. he left eye of the affected fish was severely exophthalmic because of a large intraocular tumor mass. he tumor, whi...

  2. Perspective on Open-Access Publishing: An Interview with Peter Suber

    ERIC Educational Resources Information Center

    Cornwell, Reid; Suber, Peter

    2008-01-01

    In this edition of Perspectives, Reid Cornwell discusses open-access publishing with Peter Suber, senior researcher at the Scholarly Publishing and Academic Resources Coalition, senior research professor of philosophy at Earlham College, and currently visiting fellow at Yale Law School. Open access means that scholarly work is freely and openly…

  3. Instruction in the Making: Peter Ramus and the Beginnings of Modern Schooling.

    ERIC Educational Resources Information Center

    Hamilton, David

    This paper examines educational practice between 1450-1650, highlighting 16th century educationist, Peter Ramus, whose work is remembered in the "History of Western Philosophy" as fostering a "pedagogic marvel." Ramus' work has received scant attention from English-speaking educationists, and his niche within the educational pantheon is…

  4. Robbing Peter to pay Paul: smarter re-allocation of dollars bring relief!

    PubMed

    Ledlow, Gerald R; Cwiek, Mark

    2002-01-01

    The dynamic tension facing health care organizations today is that of lower third-party payments and higher costs. The ever-present financial squeeze results in daily stressors for health care executives attempting to provide services with diminishing resources. How can one continue to "rob Peter to pay Paul," to make ends meet and stretch every dollar? PMID:12355621

  5. Michael Peters' Lyotardian Account of Postmodernism and Education: Some Epistemic Problems and Naturalistic Solutions

    ERIC Educational Resources Information Center

    Clark, John A.

    2006-01-01

    Postmodernism has established a significant hold in educational thought and some of the most important ideas are to be found in the writings of Michael Peters. This paper examines his postmodern stance and use of Lyotard's account of knowledge, and from a naturalist point of view raises a number of objections centred on science as a metanarrative,…

  6. Remaking Critical Pedagogy: Peter McLaren's Contribution to a Collective Work

    ERIC Educational Resources Information Center

    Martin, Gregory

    2006-01-01

    This article explores the collective works of Peter McLaren and his contribution to critical pedagogy within the field of education and beyond the academy. To understand how McLaren's work took a radical turn in the 1990s, the article traces the historical development of his praxis. In particular, McLaren's engagement with the postmodern Left and…

  7. Communicating Chemistry from "Molecules" to International Efforts: An Interview with Peter Atkins

    ERIC Educational Resources Information Center

    Cardellini, Liberato

    2008-01-01

    In this interview, Peter Atkins explains the deep motivations that compel him to sit at his desk at 6 AM writing books and textbooks. He discusses the four principal elements that help to make a chemistry textbook successful, including the secret ingredient. He also discusses the importance of problem solving, the interaction of multimedia, and…

  8. The Peter Effect Revisited: Reading Habits and Attitudes of College Students

    ERIC Educational Resources Information Center

    Applegate, Anthony J.; Applegate, Mary DeKonty; Mercantini, Martha A.; McGeehan, Catherine M.; Cobb, Jeanne B.; DeBoy, Joanne R.; Modla, Virginia B.; Lewinski, Kimberly E.

    2014-01-01

    Certainly a primary goal of literacy education is the creation of avid, enthusiastic, and highly motivated readers. However, in this article revisiting the Peter Effect (Applegate & Applegate, 2004), researchers surveyed more than 1,000 college sophomores and found strikingly low levels of enthusiasm for reading. Only 46.6% of surveyed…

  9. Two Causes of Underachievement--The Scapegoat Phenomenon and the Peter Pan Syndrome. Part II.

    ERIC Educational Resources Information Center

    Grau, Phyllis Nelson

    1986-01-01

    Two profiles of underachievement are described: the Peter Pan Syndrome, characterized by irresponsibility, anxiety, loneliness, sex role conflict, and narcissism, and the scapegoating phenomenon, in which children acquire negative self-images from victimization experiences. Prognoses and recommendations for each are offered. (Author/CL)

  10. Behavioral Determinants of Drug Action: The Contributions of Peter B. Dews

    ERIC Educational Resources Information Center

    Barrett, James E.

    2006-01-01

    Peter B. Dews played a significant role in shaping the distinctive characteristics and defining the underlying principles of the discipline of behavioral pharmacology. His early and sophisticated use of schedules of reinforcement in the 1950s, incorporated from research in the experimental analysis of behavior and integrated into the discipline of…

  11. "Operating on a Basis of Student Consent": Peter Medway's Work in "Finding a Language"

    ERIC Educational Resources Information Center

    Burgess, Tony

    2015-01-01

    Written nearly 40 years ago, Peter Medway's "Finding a Language" continues to be an arresting read, which offers a powerful vision of what might be possible in education. In this brief introduction, I set the work in context, referring to ideas that Pete engaged with and recalling a little of the times.

  12. R. S. Peters and J. H. Newman on the Aims of Education

    ERIC Educational Resources Information Center

    Ozolins, Janis T.

    2013-01-01

    R. S. Peters never explicitly talks about wisdom as being an aim of education. He does, however, in numerous places, emphasize that education is of the whole person and that, whatever else it might be about, it involves the development of knowledge and understanding. Being educated, he claims, is incompatible with being narrowly specialized.…

  13. Teaching Behavior Analysis and Psychology in Social Context: An Interview with Peter Harzem.

    ERIC Educational Resources Information Center

    Buskist, William

    2000-01-01

    Presents an interview with Peter Harzem, the Hudson Professor of Psychology at Auburn University (Alabama). Addresses such issues as teaching students about behavior analysis, the differences between classical and operant conditioning, reinforcement and behaviorism, and how one can become a better teacher. (CMK)

  14. Van Hiele Guidelines for Geometry.

    ERIC Educational Resources Information Center

    Davey, Geoff; Holliday, Jack

    1992-01-01

    Describes five skills underpinning the understanding of geometry for primary and lower secondary mathematics students. Skill categories identified include (1) visual; (2) verbal; (3) drawing; (4) logical; and (5) application. Gives examples of skills appropriate for Van Hiele levels 1-3. (MDH)

  15. Dens invaginatus: review, relevance, and report of 3 cases.

    PubMed

    Khan, Suleman Abbas; Khan, Saima Yunus; Bains, Vivek K; Bains, Rhythm; Loomba, Kapil

    2012-01-01

    Dens invaginatus is a rare developmental morphoanatomical variation resulting from the infolding of the dental papilla before biological mineralization that allows the invagination of inner dental epithelium. Permanent maxillary lateral incisors are most commonly affected, and the condition is frequently bilateral, but it may also prevail in permanent maxillary central incisors. The purpose of this paper was to provide an overview of the etiopathogenesis, frequency of occurrence, and clinical and radiographic features and to discuss 3 dens invaginatus cases. PMID:23433617

  16. Patterns of den occupation by the spotted hyaena (Crocuta crocuta)

    USGS Publications Warehouse

    Boydston, E.E.; Kapheim, K.M.; Holekamp, K.E.

    2006-01-01

    Spotted hyaenas utilize isolated natal dens (NDs) and communal dens (CDs) for rearing their cubs. Here we describe patterns of natal and CD occupation by hyaenas belonging to one well-studied clan in the Maasai Mara National Reserve during a 10-year period. Locations of 98 den sites that were used as natal or CDs by hyaenas in the study clan were digitized in a Geographic Information System, and the duration of use of each den site, frequency of re-use, and distances involved in den moves were quantified. Hyaenas moved their CD monthly on average. Most CD sites were occupied only once during the study, but several sites were used repeatedly. On rare occasions, the movement of hyaenas to a new den site could be attributed to a disturbance event at the CD, but factors regularly prompting hyaenas to move to new CD sites were unclear. High-ranking female hyaenas were more likely to rear their cubs from birth in a CD than low-ranking females. Low-ranking females almost always utilized isolated NDs for the first few weeks of a litter's development, and low-ranking females transferred their cubs over longer distances than did high-ranking females. ?? 2006 East African Wild Life Society.

  17. Den use by arctic foxes (Alopex lagopus) in a subarctic region of western Alaska

    USGS Publications Warehouse

    Anthony, R.M.

    1996-01-01

    Distribution, abundance, and use of arctic fox dens located in coastal tundra communities of the Yukon-Kuskokwim delta were determined in studies from 1985 to 1990. Dens were denser and less complex than those described in studies conducted above the Arctic Circle. Eighty-three dens of varying complexity were found in the 52-km2 study area. Nineteen dens were used by arctic foxes for whelping or rearing pups. Three females relocated litters to multiple dens; a maximum of four dens were used concurrently by pups from one litter. Although red foxes were common in the region, their use of dens in the study area was minimal. Differences in vegetation at den sites and nearby unoccupied sites were minimal. Furthermore, den sites could not be distinguished from non-den sites during aerial surveys.

  18. Denning chronology and design of effective bear management units

    USGS Publications Warehouse

    Inman, R.M.; Costello, C.M.; Jones, D.E.; Inman, K.H.; Thompson, B.C.; Quigley, H.B.

    2007-01-01

    Reports on the effectiveness of using late fall hunting seasons to reduce the proportion of female black bears (Ursus americanus) in the harvest are limited, and the geographic scale over which the technique functions as intended has not been examined. During 1992-2000, we radio-equipped black bears in New Mexico, USA, obtained estimates of 175 den entry and 137 den emergence dates, and used New Mexico Department of Game and Fish harvest data (1985-2000) to test for differences in proportion of females in the harvest relative to denning chronology. Bears in northern New Mexico entered dens earlier and emerged later than bears in southern New Mexico (P ??? 0.001). In northern New Mexico bears displayed the typical pattern of earlier entry and later emergence by reproductive females, proportion of females in the harvest varied over time as expected, and late fall seasons were effective (P ??? 0.10). In contrast, denning chronology did not differ by sex in southern New Mexico, proportion of females in the harvest did not change over time, and late fall seasons were not effective (P ??? 0.18). Manipulation of hunting season dates to influence female mortality can be an effective tool, however our study provides an example of an area where denning chronology did not differ by sex and late seasons were not effective. We also observed regional differences in timing of entrance and emergence, which suggest that scale of application may be key. In management jurisdictions that encompass ecologically distinct areas, cover a wide range of latitudes, or are mountainous, successful use of the technique may depend on knowledge of denning chronology at multiple locations and appropriate designation of hunting unit boundaries, season dates, and data analysis units.

  19. A girl with Peters plus syndrome associated with myelomeningocele and chronic renal failure.

    PubMed

    Motoyama, Osamu; Arai, Hiroko; Harada, Ryoko; Hasegawa, Kei; Iitaka, Kikuo

    2010-08-01

    A girl was born with sclerocornea of the right eye, corneal staphyloma of the left eye and lumbar myelomeningocele. The myelomeningocele was repaired soon after birth. The corneal staphyloma was perforated during infancy. She received keratoplasty and achieved light perception. Her right kidney revealed multicystic dysplasia and was non-functioning at birth. She had neurogenic bladder, and her renal function deteriorated gradually. Peters plus syndrome was diagnosed based on anterior ocular segment anomalies, short stature, developmental delay and characteristic face. Anterior ocular segment anomalies are rare findings, but seem to be occasionally associated with spina bifida and renal anomalies. Myelomeningocele and chronic renal failure in patients with Peters plus syndrome have not been reported to our knowledge. PMID:20424881

  20. Representing difference: Ernst Mach and Peter Salcher's ballistic-photographic experiments.

    PubMed

    Hoffmann, Christoph

    2009-03-01

    Photographs of the processes taking place in the air around a flying bullet, which the Austrian physicists Ernst Mach and Peter Salcher published in 1887, very soon became emblematic for the power of scientific photography over the human eye. But the main advantage was merely that photography allowed the phenomena in question to be recorded. This permitted a new experimental approach. The scientists were therefore not visualising phenomena by studying a single photograph but by comparing the differences between several. PMID:19201474

  1. An Interview with Peter McLaren: Comments on the State of the World-2005

    ERIC Educational Resources Information Center

    Shaughnessy, Michael F.

    2006-01-01

    Some of the wide range of thoughtful topics discussed in this interview with Peter McLaren include: (1) The top five points that McLaren tried to make in his book, "Capitalists and Conquerors: A Critical Pedagogy Against Empire"; (2) McLaren's thoughts on what he thinks the George Bush legend will be; (3) What led McLaren to ask,…

  2. A new species of the genus Diplocentrus Peters, 1861 (Scorpiones, Diplocentridae) from Oaxaca, Mexico

    PubMed Central

    Santibáñez-López, Carlos Eduardo

    2014-01-01

    Abstract A new species of the genus Diplocentrus Peters, 1861 is described, based on several specimens collected in the Mexican state of Oaxaca. It is characterized by a high telotarsal spiniform setae count (4-5/5:5/6:6/6:6/6-7), and the pectinal tooth counts of 12–15, mode = 13 (male) or 11–13, mode = 12 (female). With the description of this species, the diversity of the genus is increased to 51 species in Mexico. PMID:24899864

  3. Regional diagenetic patterns in the St. Peter Sandstone; implications for brine migration in the Illinois Basin

    USGS Publications Warehouse

    Pitman, Janet K.; Goldhaber, Martin B.; Spoetl, Christoph

    1997-01-01

    Diagenetic minerals and alteration patterns in the Ordovician St. Peter Sandstone, Illinois Basin, record varied hydrologic and chemical conditions during the basin?s long and complex geologic history. Major diagenetic events modifying the St. Peter Sandstone include (1) mechanical compaction, (2) early K-feldspar overgrowth and dolospar precipitation, (3) burial quartz, dolospar, anhydrite, and calcite cementation, and (4) carbonate-cement and K-feldspar grain dissolution. Radiometric age dates of authigenic K-feldspar and illite in combination with the reconstructed burial history of the St. Peter reveal that early-diagenetic K-feldspar and dolospar precipitated at shallow to moderate depths in the Devonian, whereas late-diagenetic quartz, dolospar, anhydrite, and calcite formed during deep burial in the Late Pennsylvanian to Early Permian. Stable-isotope geochemistry and fluid-inclusion paleothermometry suggest that burial cements precipitated from saline fluids over a wide temperature range. In the southern part of the basin, burial cements preserve a record of diagenetic effects that were in part controlled by fractures and hydrothermal-fluid circulation. Baroque dolospar cementation is the most significant of these effects.

  4. Remote identification of polar bear maternal den habitat in northern Alaska

    USGS Publications Warehouse

    Durner, G.M.; Amstrup, Steven C.; Ambrosius, K.J.

    2001-01-01

    Polar bears (Ursus maritimus) give birth in dens of ice and snow to protect their altricial young. During the snow-free season, we visited 25 den sites located previously by radiotelemetry and characterized the den site physiognomy. Seven dens occurred in habitats with minimal relief. Eighteen dens (72%) were in coastal and river banks. These "banks" were identifiable on aerial photographs. We then searched high-resolution aerial photographs (n = 3000) for habitats similar to those of the 18 dens. On aerial photos, we mapped 1782 km of bank habitats suitable for denning. Bank habitats comprised 0.18% of our study area between the Colville River and the Tamayariak River in northern Alaska. The final map, which correctly identified 88% of bank denning habitat in this region, will help minimize the potential for disruptions of maternal dens by winter petroleum exploration activities.

  5. Detecting denning polar bears with Forward-Looking Infrared (FLIR) imagery

    USGS Publications Warehouse

    Amstrup, Steven C.; York, G.; McDonald, T.L.; Nielson, R.; Simac, K.

    2004-01-01

    Polar bears give birth in snow dens in midwinter and remain in dens until early spring. The survival and development of cubs is dependent on a stable environment within the maternal den. To mitigate potential disruption of polar bear denning by existing and proposed petroleum activities, we used forward-looking infrared (FLIR) viewing to try to detect heat rising from dens.We flew transects over dens of radio-collared females with FLIR imager-equipped aircraft, recorded weather conditions at each observation, and noted whether the den was detected.We surveyed 23 dens on 67 occasions (1 to 7 times each). Nine dens were always detected, and 10 dens visited more than once were detected on some flights but not on others. Four dens were never detected (17 percent), but three of those were visited only under marginal conditions. The odds of detecting a den were 4.8 times greater when airborne moisture (snow, blowing snow, fog, etc.) was absent than when it was present, and they increased 3-fold for every 1?C increase in temperature-dew point spread. The estimated probability of detecting dens in sunlight was 0. Data suggested that FLIR surveys conducted during optimal conditions for detection can produce detection rates approaching 90 percent and thus can be an important management and mitigation tool. polar bear, infrared imagery, maternal denning, human impacts, management

  6. American black bear denning behavior: Observations and applications using remote photography

    USGS Publications Warehouse

    Bridges, A.S.; Fox, J.A.; Olfenbuttel, C.; Vaughan, M.B.

    2004-01-01

    Researchers examining American black bear (Ursus americanus) denning behavior have relied primarily on den-site visitation and radiotelemetry to gather data. Repeated den-site visits are time-intensive and may disturb denning bears, possibly causing den abandonment, whereas radiotelemetry is sufficient only to provide gross data on den emergence. We used remote cameras to examine black bear denning behavior in the Allegheny Mountains of western Virginia during March-May 2003. We deployed cameras at 10 den sites and used 137 pictures of black bears. Adult female black bears exhibited greater extra-den activity than we expected prior to final den emergence, which occurred between April 12 and May 6, 2003. Our technique provided more accurate den-emergence estimation than previously published methodologies. Additionally, we observed seldom-documented behaviors associated with den exits and estimated cub age at den emergence. Remote cameras can provide unique insights into denning ecology, and we describe their potential application to reproductive, survival, and behavioral research.

  7. Habitat characteristics of polar bear terrestrial maternal den sites in northern Alaska

    USGS Publications Warehouse

    Durner, G.M.; Amstrup, Steven C.; Fischbach, Anthony S.

    2003-01-01

    Polar bears (Ursus maritimus) give birth to and nurture their young in dens of ice and snow. During 1999-2001, we measured the structure of 22 dens on the coastal plain of northern Alaska after polar bear families had evacuated their dens in the spring. During the summers of 2001 and 2002, we revisited the sites of 42 maternal and autumn exploratory dens and recorded characteristics of the under-snow habitat. The structure of polar bear snow dens was highly variable. Most were simple chambers with a single entrance/egress tunnel. Others had multiple chambers and additional tunnels. Thickness of snow above and below dens was highly variable, but most dens were overlain by less than 1 m of snow. Dens were located on, or associated with, pronounced landscape features (primarily coastal and river banks, but also a lake shore and an abandoned oil field gravel pad) that are readily distinguished from the surrounding terrain in summer and catch snow in early winter. Although easily identified, den landforms in northern Alaska were more subtle than den habitats in many other parts of the Arctic. The structure of polar bear dens in Alaska was strikingly similar to that of dens elsewhere and has remained largely unchanged in northern Alaska for more than 25 years. Knowledge of den structure and site characteristics will allow resource managers to identify habitats with the greatest probability of holding dens. This information may assist resource managers in preventing negative impacts of mineral exploration and extraction on polar bears.

  8. Indoor Radon Measurement in Van

    SciTech Connect

    Kam, E.; Osmanlioglu, A. E.; Celebi, N.; Dogan, I.

    2007-04-23

    In this study, indoor radon concentrations obtained from the radon surveys conducted in the Van. Radon monitoring was performed by applying a passive, time-integrating measuring technique. For this purpose, CR-39 nuclear track detectors were installed in dwellings for 2 months. After the monitoring period, detectors were collected. In order to make the alpha tracks visible, chemical etching was applied to the exposed detectors. Nuclear track numbers and the corresponding indoor radon concentrations were determined. Annual effective dose equivalents and the risk probabilities caused by indoor radon inhalation were calculated, and the found results compared with the indoor radon concentrations' data measured in different provinces of Turkey.

  9. Prophylactic treatment of dens evaginatus using mineral trioxide aggregate.

    PubMed

    Koh, E T; Ford, T R; Kariyawasam, S P; Chen, N N; Torabinejad, M

    2001-08-01

    Two case reports with dens evaginatus are presented. Each patient had one tooth affected. There was a prominent tubercle on the occlusal surface of the mandibular second premolar. Under local anesthesia and rubber dam isolation a partial pulpotomy was conducted and mineral trioxide aggregate was placed. After 6 months the teeth were removed as part of planned orthodontic treatment. Histological examination of these teeth showed an apparent continuous dentin bridge formation in both teeth, and the pulps were free of inflammation. These cases show that mineral trioxide aggregate can be used as an alternative to existing materials in the proplylactic treatment of dens evaginatus. PMID:11501594

  10. Denning habits of free-ranging dogs reveal preference for human proximity.

    PubMed

    Sen Majumder, Sreejani; Paul, Manabi; Sau, Shubhra; Bhadra, Anindita

    2016-01-01

    Dens are crucial in the early development of many mammals, making den site selection an important component of parental care in such species. Resource availability and shelter from predators primarily govern den selection. Species inhabiting human-dominated landscapes typically den away from human disturbance, often shifting dens to avoid humans during the early life of their young. Domesticated dogs have evolved in human proximity over centuries, being bred and reared in human homes for generations. While pets rely on their owners for shelter and care, free-ranging dogs roam uncared, and typically whelp in dens. We conducted a study on 148 free-ranging dog dens in India to understand their denning habits. Distance from resources influenced den choice, but anthropogenic disturbance did not. Dens were found in areas of high human activity, and begging from humans was preferred over scavenging. A study on 15 pregnant females revealed that females actively searched for denning sites, rejecting several intermediate ones before selecting the final den. We propose that the obvious preference of dogs for denning close to humans is a behavioural adaptation that helps them to survive in the urban landscape, in spite of the high human induced mortality during the early life of pups. PMID:27535214

  11. Denning habits of free-ranging dogs reveal preference for human proximity

    PubMed Central

    Sen Majumder, Sreejani; Paul, Manabi; Sau, Shubhra; Bhadra, Anindita

    2016-01-01

    Dens are crucial in the early development of many mammals, making den site selection an important component of parental care in such species. Resource availability and shelter from predators primarily govern den selection. Species inhabiting human-dominated landscapes typically den away from human disturbance, often shifting dens to avoid humans during the early life of their young. Domesticated dogs have evolved in human proximity over centuries, being bred and reared in human homes for generations. While pets rely on their owners for shelter and care, free-ranging dogs roam uncared, and typically whelp in dens. We conducted a study on 148 free-ranging dog dens in India to understand their denning habits. Distance from resources influenced den choice, but anthropogenic disturbance did not. Dens were found in areas of high human activity, and begging from humans was preferred over scavenging. A study on 15 pregnant females revealed that females actively searched for denning sites, rejecting several intermediate ones before selecting the final den. We propose that the obvious preference of dogs for denning close to humans is a behavioural adaptation that helps them to survive in the urban landscape, in spite of the high human induced mortality during the early life of pups. PMID:27535214

  12. Van Go: A Labor of Love

    ERIC Educational Resources Information Center

    Williams, Jennifer

    2012-01-01

    Like a tapestry woven with one outstanding thread from beginning to end, the author's forty-year tenure as an art educator has its golden thread in her Van Go art outreach project. Quite literally, she takes students in a "van" and they "go," mostly on dirt roads, taking art to rural schools in Idaho, some of which have no more than three students…

  13. Fishers' knowledge as a source of information about the estuarine dolphin (Sotalia guianensis, van Bénéden, 1864).

    PubMed

    Manzan, Maíra Fontes; Lopes, Priscila F M

    2015-01-01

    Fishers' local ecological knowledge (LEK) is an additional tool to obtain information about cetaceans, regarding their local particularities, fishing interactions, and behavior. However, this knowledge could vary in depth of detail according to the level of interaction that fishers have with a specific species. This study investigated differences in small-scale fishers' LEK regarding the estuarine dolphin (Sotalia guianensis) in three Brazilian northeast coastal communities where fishing is practiced in estuarine lagoons and/or coastal waters and where dolphin-watching tourism varies from incipient to important. The fishers (N = 116) were asked about general characteristics of S. guianensis and their interactions with this dolphin during fishing activities. Compared to lagoon fishers, coastal fishers showed greater knowledge about the species but had more negative interactions with the dolphin during fishing activities. Coastal fishing not only offered the opportunity for fishers to observe a wider variety of the dolphin's behavior, but also implied direct contact with the dolphins, as they are bycaught in coastal gillnets. Besides complementing information that could be used for the management of cetaceans, this study shows that the type of environment most used by fishers also affects the accuracy of the information they provide. When designing studies to gather information on species and/or populations with the support of fishers, special consideration should be given to local particularities such as gear and habitats used within the fishing community. PMID:25399120

  14. Den-site characteristics of black bears in Rocky Mountain National Park, Colorado

    USGS Publications Warehouse

    Baldwin, R.A.; Bender, L.C.

    2008-01-01

    We compared historic (1985-1992) and contemporary (2003-2006) black bear (Ursus americanus) den locations in Rocky Mountain National Park (RMNP), Colorado, USA, for habitat and physiographic attributes of den sites and used maximum entropy modeling to determine which factors were most influential in predicting den-site locations. We observed variability in the relationship between den locations and distance to trails and elevation over rime. Locations of historic den sites were most associated with slope, elevation, and covertype, whereas contemporary sites were associated with slope, distance to roads, aspect, and canopy height. Although relationships to covariates differed between historic and contemporary periods, preferred den-site characteristics consistently included steep slopes and factors associated with greater snow depth. Distribution of den locations shifted toward areas closer to human developments, indicating little negative influence of this factor on den-site selection by black bears in RMNP.

  15. Some single-piston closed-cycle machines and Peter Tailer's thermal lag engine

    NASA Astrophysics Data System (ADS)

    West, C. D.

    1993-05-01

    Peter Tailer has devised, built, and operated a beautifully simple engine with a closed working gas cycle, external heating, and only a single piston. The aim of this paper is to cast some light on the possible modes of operation for his machine. The methods developed to analyze certain aspects of Stirling cycle engines, and especially the thermodynamic losses incurred in systems that are neither perfectly isothermal nor perfectly adiabatic, can be applied to Tailer's system. The results identify two idealized cycles fr such machines; relate those cycles to a single piston, ported cylinder machine proposed earlier; and offer a possible explanation for the success of the thermal lag engine.

  16. Language and Reality. Peter Mittelstaedt's Contributions to the Philosophy of Physics

    NASA Astrophysics Data System (ADS)

    Falkenburg, Brigitte

    2010-10-01

    The article investigates the way in which Peter Mittelstaedt has been contributing to the philosophy of physics for half a century. It is shown that he pursues a path between rationalism and empiricism in the sense of Erhard Scheibe’s philosophy of the physicists. Starting from Kant’s a priori he gives a rational reconstruction of the conceptual revolutions of 20th century physics. The central topic of his philosophy of physics is the quest for semantic self-consistency, which for quantum mechanics is a hard nut to crack.

  17. Communicating Chemistry from Molecules to International Efforts: An Interview with Peter Atkins

    NASA Astrophysics Data System (ADS)

    Cardellini, Liberato

    2008-06-01

    In this interview, Peter Atkins explains the deep motivations that compel him to sit at his desk at 6 AM writing books and textbooks. He discusses the four principal elements that help to make a chemistry textbook successful, including the secret ingredient. He also discusses the importance of problem solving, the interaction of multimedia, and the effect of the Web on textbooks. Finally, Atkins articulates the beliefs that learning chemistry opens our eyes to a deeper enjoyment of the world, that chemistry plumbs a deeper level of reality.

  18. Forest inventory: Peter T. Johnson Wildlife Mitigation Unit, Craig Mountain, Idaho. Final Report.

    SciTech Connect

    Narolski, Steven W.

    1996-12-01

    The primary objective of this report is to determine the quantity and quality of existing forest habitat types on the 59,991-acre Peter T. Johnson Wildlife Mitigation Unit (WMU). Products from this effort include a description of the ecological condition, a map of habitat types, and an inventory of forest resources on the WMU lands. The purpose of this and other resource inventories (plant and wildlife) is to assess the current resources condition of the WMU and to provide necessary information to generate a long-term management for this area.

  19. Peter Andreas Hansen und die astronomische Gemeinschaft - eine erste Auswertung des Hansen-Nachlasses.

    NASA Astrophysics Data System (ADS)

    Schwarz, O.; Strumpf, M.

    The literary assets of Peter Andreas Hansen are deposited in the Staatsarchiv Hamburg, the Forschungs- und Landesbibliothek Gotha and the Thüringer Staatsarchiv Gotha. They were never systematically investigated. The authors present here some results of a first evaluation. It was possible to reconstruct the historical events with regard to the maintenance of the Astronomische Nachrichten and the Altona observatory in 1854. Hansen was a successful teacher for many young astronomers. His way of stimulating the evolution of astronomy followed Zach's tradition.

  20. Effect of Ethanol on Branchial Adenosine Triphosphatases in Oreochromis mossambicus (Peters)

    PubMed Central

    Bhanu, Smitha V.; Philip, Babu

    2011-01-01

    The aim of this work was to determine the toxicity of ethanol in an aquatic system by means of bioassays with Oreochromis mossambicus (Peters) as a test organism. The study revealed changes in the gill ATPase activities. The results obtained indicated that ethanol brought about a decrease in the body weight, followed by significant inhibition on total ATPase, Na+/K+ ATPase, Ca2+ ATPase and Mg2+ ATPase activities. The studies also indicated that these can be employed as suitable biomarkers in ethanol related toxicity studies. PMID:21430917

  1. Grizzly bear denning chronology and movements in the Greater Yellowstone Ecosystem

    USGS Publications Warehouse

    Haroldson, Mark A.; Ternent, Mark A.; Gunther, Kerry A.; Schwartz, Charles C.

    2002-01-01

    Den entrance and emergence dates of grizzly bears (Ursus arctos) in the Greater Yellowstone Ecosystem are important to management agencies that wish to minimize impacts of human activities on bears. Current estimates for grizzly bear denning events use data that were collected from 1975–80. We update these estimates by including data obtained from 1981–99. We used aerial telemetry data to estimate week of den entry and emergence by determining the midpoint between the last known active date and the first known date denned, as well as the last known date denned and the first known active date. We also investigated post emergence movement patterns relative to den locations. Mean earliest and latest week of den entry and emergence were also determined. Den entry for females began during the fourth week in September, with 90% denned by the fourth week of November. Earliest den entry for males occurred during the second week of October, with 90% denned by the second week of December. Mean week of den entry for known pregnant females was earlier than males. Earliest week of den entry for known pregnant females was earlier than other females and males. Earliest den emergence for males occurred during the first week of February, with 90% of males out of dens by the fourth week of April. Earliest den emergence for females occurred during the third week of March; by the first week of May, 90% of females had emerged. Male bears emerged from dens earlier than females. Denning period differed among classes and averaged 171 days for females that emerged from dens with cubs, 151 days for other females, and 131 days for males. Known pregnant females tended to den at higher elevations and, following emergence, remained at higher elevation until late May. Females with cubs remained relatively close (<3 km) to den sites until the last 2 weeks in May. Timing of denning events was similar to previous estimates for this and other grizzly bear populations in the southern Rocky

  2. Detection of both vanA & vanB genes in vanA phenotypes of Enterococci by Taq Man RT-PCR

    PubMed Central

    Mirzaei, Bahman; Babaei, Ryhane; Asiabar, Akbar Pour Dadash; Bameri, Zakaria

    2015-01-01

    Twenty seven isolates of vancomycin resistant Enterococci based on the disk diffusion and E- test have been screened; being found eight (0.3%) clinical isolates of vanA & vanB through Taq Man Real Time PCR assay. This study shows the presence of both vanA & vanB genotypes in vanA phenotypes clinical isolates in the three hospitals in Iran. PMID:26221103

  3. Occurrence of the vancomycin-resistant genes vanA, vanB, vanCl, vanC2 and vanC3 in Enterococcus strains isolated from poultry and pork.

    PubMed

    Lemcke, R; Bülte, M

    2000-09-25

    It is suspected that the use of avoparcin as a feeding antibiotic for the fat stock contributes to development of cross-resistance against vancomycin and teicoplanin. After isolating enterococci strains from poultry and pork meat by cultivation on citrate azide Tween carbonate agar (CATC) and screening the vancomycin resistance on Columbia colistin nalidixic acid agar (CNA, supplemented with 5% sheepblood and 5 mg vancomycin/l) the polymerase chain reaction (PCR) was used for the detection of the vancomycin resistance genes vanA ('high level'), vanB ('moderate high level'), vanC1, vanC2 and vanC3 ('low level'). Out of 1643 E.-isolates from 115 poultry and 50 pork samples, 420 isolates could be identified as vancomycin resistant, 202 isolates of which carry the vanA, one isolate both the vanA and the vanC1, 38 isolates the vanC1, 14 isolates the vanC2, nine isolates both the vanC1 and the vanC3 gene and 156 isolates carry no gene. The vanB gene was not found in these isolates. Comparing vanA-positive food isolates with those from different human sources by means of the pulsed field gel electrophoresis (PFGE) it could clearly be demonstrated that they do not show homological fingerprints according to the source of origin. It is therefore unlikely that there is a close genetic relationship between isolates from animal foodstuff and humans. PMID:11016608

  4. Evolution of Capsaicinoids in Peter Pepper (Capsicum annuum var. annuum) During Fruit Ripening.

    PubMed

    Barbero, Gerardo F; de Aguiar, Ana C; Carrera, Ceferino; Olachea, Ángel; Ferreiro-González, Marta; Martínez, Julian; Palma, Miguel; Barroso, Carmelo G

    2016-08-01

    The evolution of individual and total contents of capsaicinoids present in Peter peppers (Capsicum annuum var. annuum) at different ripening stages has been studied. Plants were grown in a glasshouse and the new peppers were marked in a temporal space of ten days. The extraction of capsaicinoids was performed by ultrasound-assisted extraction with MeOH. The capsaicinoids nordihydrocapsaicin (n-DHC), capsaicin, dihydrocapsaicin, homocapsaicin, and homodihydrocapsaicin were analyzed by ultraperformance liquid chromatography (UHPLC)-fluorescence and identified by UHPLC-Q-ToF-MS. The results indicate that the total capsaicinoids increase in a linear manner from the first point of harvest at ten days (0.283 mg/g FW) up to 90 days, at which point they reach a concentration of 1.301 mg/g FW. The evolution as a percentage of the individual capsaicinoids showed the initial predominance of capsaicin, dihydrocapsaicin, and n-DHC. Dihydrocapsaicin was the major capsaicinoid up to day 50 of maturation. After 50 days, capsaicin became the major capsaicinoid as the concentration of dihydrocapsaicin fell slightly. The time of harvest of Peter pepper based on the total capsaicinoids content should be performed as late as possible. In any case, harvesting should be performed before overripening of the fruit is observed. PMID:27416068

  5. A reconstructive surgeon's taste in art: Dr Peter Parker and the Lam Qua oil paintings.

    PubMed

    Chang, J

    1993-05-01

    Hidden within the basement archives of Yale University's Historical Medical Library lie the original oil painting collection and personal papers of the first American surgeon to practice in China. The Reverend Dr Peter Parker, a graduate of Yale, established the first American hospital in Guangzhou (formerly Canton) in 1835 and successfully introduced Western surgical techniques including amputation, anesthesia, and reconstructive surgery. In addition to this distinguished career of medical missionary service, Parker commissioned the Chinese artist Lam Qua to paint a fascinating series of portraits depicting patients with extreme tumor growths. In this article, Parker's own journals are examined to reveal both his missionary zeal and his frustrations working in China. Selected examples of the Lam Qua paintings are presented along with Parker's corresponding patient descriptions. These detailed patient reports give insight into the extent of surgical pathology as well as the relative brutality of surgical techniques in the early to mid-1800s. The historical significance of the Peter Parker-Lam Qua collaboration within the context of the Western transformation of Chinese art and medicine is also discussed. PMID:8342936

  6. Performance Evaluation Tests for Environmental Research (PETER): evaluation of 114 measures

    NASA Technical Reports Server (NTRS)

    Bittner, A. C. Jr; Carter, R. C.; Kennedy, R. S.; Harbeson, M. M.; Krause, M.

    1986-01-01

    The goal of the Performance Evaluation Tests for Environmental Research (PETER) Program was to identify a set of measures of human capabilities for use in the study of environmental and other time-course effects. 114 measures studied in the PETER Program were evaluated and categorized into four groups based upon task stability and task definition. The Recommended category contained 30 measures that clearly obtained total stabilization and had an acceptable level of reliability efficiency. The Acceptable-But-Redundant category contained 15 measures. The 37 measures in the Marginal category, which included an inordinate number of slope and other derived measures, usually had desirable features which were outweighed by faults. The 32 measures in the Unacceptable category had either differential instability or weak reliability efficiency. It is our opinion that the 30 measures in the Recommended category should be given first consideration for environmental research applications. Further, it is recommended that information pertaining to preexperimental practice requirements and stabilized reliabilities should be utilized in repeated-measures environmental studies.

  7. ARPES studies of van der Waals heterostructure

    NASA Astrophysics Data System (ADS)

    Wang, Eryin; Lu, Xiaobo; Chen, Guorui; Fedorov, Alexei V.; Zhang, Yuanbo; Zhang, Guangyu; Zhou, Shuyun

    Van der Waals heterostructures are a novel class of ``materials by design'' which are formed by stacking different two-dimensional crystals together via van der Waals interaction. The periodic potential by the Moir é superlattice can be used as a control knob for tuning the electronic properties of two dimensional materials and can induce various novel quantum phenomena. Here we report direct electronic structure studies the of a model van der Waals heterostructure using angle-resolved photoemission spectroscopy (ARPES). This work is supported by the National Natural Science Foundation of China and Ministry of Education of China.

  8. Van Allsburg: From a Different Perspective.

    ERIC Educational Resources Information Center

    McKee, Barbara

    1986-01-01

    Criticizes the illustrations of characters in children's books created by C. Van Allsburg. Concludes that in his latest works the awkwardness of figure execution is disappearing and being replaced by a deeper psychological interpretation of character. (SRT)

  9. Genetics Home Reference: van der Woude syndrome

    MedlinePlus

    ... people with this disorder are born with a cleft lip , a cleft palate (an opening in the roof ... People with van der Woude syndrome who have cleft lip and/or palate, like other individuals with these ...

  10. Selection of den sites by black bears in the southern Appalachians

    USGS Publications Warehouse

    Reynolds-Hogland, M. J.; Mitchell, M.S.; Powell, R.A.; Brown, D.C.

    2007-01-01

    We evaluated selection of den sites by American black bears (Ursus americanus) in the Pisgah Bear Sanctuary, western North Carolina, by comparing characteristics of dens at 53 den sites with availability of habitat characteristics in annual home ranges of bears and in the study area. We also tested whether den-site selection differed by sex, age, and reproductive status of bears. In addition, we evaluated whether the den component of an existing habitat model for black bears predicted where bears would select den sites. We found bears selected den sites far from gravel roads, on steep slopes, and at high elevations relative to what was available in both annual home ranges and in the study area. Den-site selection did not differ by sex or age, but it differed by reproductive status. Adult females with cubs preferred to den in areas that were relatively far from gravel roads, but adult females without cubs did not. The habitat model overestimated the value of areas near gravel roads, underestimated the value of moderately steep areas, and did not include elevation as a predictor variable. Our results highlight the importance of evaluating den selection in terms of both use and availability of den characteristics. ?? 2007 American Society of Mammalogists.

  11. A female black bear denning habitat model using a geographic information system

    USGS Publications Warehouse

    Clark, J.D.; Hayes, S.G.; Pledger, J.M.

    1998-01-01

    We used the Mahalanobis distance statistic and a raster geographic information system (GIS) to model potential black bear (Ursus americanus) denning habitat in the Ouachita Mountains of Arkansas. The Mahalanobis distance statistic was used to represent the standard squared distance between sample variates in the GIS database (forest cover type, elevation, slope, aspect, distance to streams, distance to roads, and forest cover richness) and variates at known bear dens. Two models were developed: a generalized model for all den locations and another specific to dens in rock cavities. Differences between habitat at den sites and habitat across the study area were represented in 2 new GIS themes as Mahalanobis distance values. Cells similar to the mean vector derived from the known dens had low Mahalanobis distance values, and dissimilar cells had high values. The reliability of the predictive model was tested by overlaying den locations collected subsequent to original model development on the resultant den habitat themes. Although the generalized model demonstrated poor reliability, the model specific to rock dens had good reliability. Bears were more likely to choose rock den locations with low Mahalanobis distance values and less likely to choose those with high values. The model can be used to plan the timing and extent of management actions (e.g., road building, prescribed fire, timber harvest) most appropriate for those sites with high or low denning potential. 

  12. Raccoon (Procyon lotor) diurnal den use within an intensively managed forest in central West Virginia

    USGS Publications Warehouse

    Owen, Sheldon F.; Berl, Jacob L.; Edwards, John W.; Ford, W. Mark; Wood, Petra Bohall

    2015-01-01

    Intensive forest management may influence the availability of suitable den sites for large den-seeking species, such as Procyon lotor (Raccoon). As part of a Raccoon ecology study on an industrial forest in the Allegheny Mountains of central West Virginia, we radio-tracked 32 Raccoons to 175 diurnal den sites to determine relative use of dens that included cavity trees, rock dens, log piles, slash piles, and exposed limbs. Patterns of den use significantly differed between sexes and among seasons. Overall, we recorded 58 cavity dens in 12 tree species with 7 maternal dens found in 5 tree species. Raccoons selected larger-diameter den trees than available cavity trees and non-cavity trees. Because the abundance of suitable tree cavities is known to influence Raccoon densities and recruitment at fine spatial scales and female Raccoons in this study used tree cavities as maternal den sites, the continued harvest of large-diameter trees (i.e., those capable of developing den cavities) without replacement may impact Raccoon recruitment within intensively managed forests throughout the central Appalachians.

  13. Van Allen Discovery Most Important

    NASA Technical Reports Server (NTRS)

    Jastrow, R.

    1959-01-01

    The first step toward the exploration of space occurred approximately 22 months ago as a part of the International Geophysical Year. In the short interval since October, 1957, the new tools of research, the satellite and the space rocket, have produced two unexpected results of fundamental scientific importance. First, instruments placed in the Explorer satellites by James A. Van Allen have revealed the existence of layers of energetic particles in the outer atmosphere. This discovery constitutes the most significant research achievement of the IGY satellite program. The layers may provide the explanation for the aurora and other geophysical phenomena, and they will also influence the design of vehicles for manned space flight, whose occupants must be shielded against their harmful biological effects. Second, the shape of the earth has been determined very accurately with the aid of data from the first Vanguard. As a result of this investigation, we have found that our planet tends toward the shape of a pear, with its stem at the North Pole. This discovery may produce major changes in our ideas on the interior structure of the earth.

  14. Nodal Statistics for the Van Vleck Polynomials

    NASA Astrophysics Data System (ADS)

    Bourget, Alain

    The Van Vleck polynomials naturally arise from the generalized Lamé equation as the polynomials of degree for which Eq. (1) has a polynomial solution of some degree k. In this paper, we compute the limiting distribution, as well as the limiting mean level spacings distribution of the zeros of any Van Vleck polynomial as N --> ∞.

  15. 19 CFR 10.41a - Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments of international...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... the List of CFR Sections Affected, which appears in the Finding Aids section of the printed volume and... 19 Customs Duties 1 2012-04-01 2012-04-01 false Lift vans, cargo vans, shipping tanks, skids... Traffic § 10.41a Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments...

  16. 19 CFR 10.41a - Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments of international...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... the List of CFR Sections Affected, which appears in the Finding Aids section of the printed volume and... 19 Customs Duties 1 2011-04-01 2011-04-01 false Lift vans, cargo vans, shipping tanks, skids... Traffic § 10.41a Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments...

  17. Peter Becker and his Nazi past: the man behind Becker muscular dystrophy and Becker myotonia.

    PubMed

    Zeidman, Lawrence A; Kondziella, Daniel

    2014-04-01

    Peter Becker was a German neurologist who helped classify the muscular dystrophies, and described Becker muscular dystrophy and Becker myotonia. His involvement in National Socialism began in 1933, when he was compelled by his peers to join the SA (brown shirts). He later joined the Nazi party, the Nazi Doctors Association, and the Nazi Lecturers' Association. He renewed his SA membership to maintain his position at a genetics institute. Colleagues stated postwar that he was not an active Nazi, and he was de-Nazified in 1947, able to continue his career. Later, Becker admitted to most, but not all, of his Nazi memberships in his autobiography, and wrote 2 books exploring the origins of Nazism and racial hygiene. The "neurologic court of opinion" must weigh in on how we should best remember Becker, and at the very least, we as neurologists must learn the dangers of career opportunism at any cost. PMID:23576413

  18. Analyses and description of geochemical samples, Peters Mountain Wilderness Study Area, Giles County, Virginia

    USGS Publications Warehouse

    Rait, Norma; Lesure, Frank Gardner

    1978-01-01

    Semiquantitative emission spectrographic analyses for 64 elements on 43 stream sediment and 73 rock samples from Peters Mountain Wilderness Study area, Giles County, Virginia, are reported here in detail. Locations for all samples are in Universal Transverse Mercator (UTM) coordinates. Brie[ descriptions of rock samples are also included. Rocks analysed are mostly sandstone. Samples of hematitic sandstone of the Rose Hill Formation and limonite-cemented sandstone of the Rocky Gap Sandstone contain high values of iron; these rocks are submarginal iron resources. Some of the same iron-rich samples have a little more barium, copper, cobalt, lead, silver, and/or zinc then average sandstone, but they do not suggest the presence of economic deposits of these metals. No other obviously anomalous values related to mineralized rock are present in the data.

  19. Yes! There is an ethics of care: an answer for Peter Allmark.

    PubMed Central

    Bradshaw, A

    1996-01-01

    This paper is a response to Peter Allmark's thesis that 'there can be no "caring" ethics'. It argues that the current preoccupation in nursing to define an ethics of care is a direct result of breaking nursing tradition. Subsequent attempts to find a moral basis for care, whether from subjective experimental perspectives such as described by Noddings, or from rational and detached approaches derived from Kant, are inevitably flawed. Writers may still implicitly presuppose a concept of care drawn from the Judaeo-Christian tradition but without explicit recourse to its moral basis nursing is left rudderless and potentially without purpose. The very concept of 'care' cut off from its roots becomes a meaningless term without either normative or descriptive content. PMID:8932719

  20. Peter Bourne's drug policy and the perils of a public health ethic, 1976-1978.

    PubMed

    Clark, Claire D; Dufton, Emily

    2015-02-01

    As President Jimmy Carter's advisor for health issues, Peter Bourne promoted a rational and comprehensive drug strategy that combined new supply-side efforts to prevent drug use with previously established demand-side addiction treatment programs. Using a public health ethic that allowed the impact of substances on overall population health to guide drug control, Bourne advocated for marijuana decriminalization as well as increased regulations for barbiturates. A hostile political climate, a series of rumors, and pressure from both drug legalizers and prohibitionists caused Bourne to resign in disgrace in 1978. We argue that Bourne's critics used his own public health framework to challenge him, describe the health critiques that contributed to Bourne's resignation, and present the story of his departure as a cautionary tale for today's drug policy reformers. PMID:25521893

  1. Common ground on surgical abortion?--engaging Peter Singer on the moral status of potential persons.

    PubMed

    Camosy, Charles C

    2008-12-01

    The debate over surgical abortion is certainly one of the most divisive in ethical discourse and for many it seems interminable. However, this paper argues that a primary reason for this is confusion with regard to what issues are actually under dispute. When looking at an entrenched and articulate figure on one side of the debate, Peter Singer, and comparing his views with those of his opponents, one finds that the disputed issue is actually quite a narrow one: the moral status of potential persons. Finding this common ground clears the conceptual space for a fruitful argument: the thesis of which is that most, including Singer, who argue that potential persons do not have full personal moral status fail to make the necessary distinction between natural potential (which confers moral status) and practical potential (which admittedly does not). PMID:19098134

  2. Sir Peter Medawar: science, creativity and the popularization of Karl Popper

    PubMed Central

    Calver, Neil

    2013-01-01

    Sir Peter Medawar was respected by scientists and literati alike. It was perhaps not surprising, then, that he would choose to involve himself in the ‘two cultures’ debate of 1959 and beyond. The focus of his intervention was the philosophy of Sir Karl Popper. However, Medawar's Popper was not the guru of falsification familiar from philosophy textbooks. Medawar's distinctive interpretation of Popper treated him instead as the source of insights into the role of creativity and imagination in scientific inquiry. This paper traces the context for Medawar's adoption of Popperian philosophy, together with its application before the debate. It then examines, within the context of the debate itself, the way in which Medawar attempted to reconcile scientific inquiry with literary practice. Medawar became increasingly convinced that not only was induction epistemologically unsound, but it was also damaging to the public role of the scientist. His construction of Popperianism would, he envisaged, provide a worthy alternative for scientists’ self-image.

  3. "The physician as poet" review of: Pereira, Peter Saying the World

    PubMed Central

    Weishaus, Joel

    2006-01-01

    Peter Pereira is a family physician and a poet. I weave excerpts from Dr. Pereira's poems into a brief history of medicine's mythological and historical roots, beginning with the Egyptian god Thoth, and the Greek physician Hippocrates. Along the way, I touch on the European Middle Ages and the Islamic World. Finally, I quote poet-critic T.S. Eliot, who was an early influence on Dr. Pereira's decision to become a poet, and contemporary physician-poets Rafael Campo and William Carlos Williams. I end by placing Dr. Pereira, whose practice is oriented toward immigrant families, in his indigenous Pacific Northwest, arguing that being both physician and poet helps Pereira to live in a world that is both intimately human and naturally impersonal.

  4. Dr. Peter Cavanaugh Explains the Need and Operation of the FOOT Experiment

    NASA Technical Reports Server (NTRS)

    2003-01-01

    This video clip is an interview with Dr. Peter Cavanaugh, principal investigator for the FOOT experiment. He explains the reasoning behind the experiment and shows some video clips of the FOOT experiment being calibrated and conducted in orbit. The heart of the FOOT experiment is an instrumented suit called the Lower Extremity Monitoring Suit (LEMS). This customized garment is a pair of Lycra cycling tights incorporating 20 carefully placed sensors and the associated wiring control units, and amplifiers. LEMS enables the electrical activity of the muscles, the angular motions of the hip, knee, and ankle joints, and the force under both feet to be measured continuously. Measurements are also made on the arm muscles. Information from the sensors can be recorded up to 14 hours on a small, wearable computer.

  5. Ellis-van Creveld syndrome.

    PubMed

    Baujat, Geneviève; Le Merrer, Martine

    2007-01-01

    Ellis-van Creveld syndrome (EVC) is a chondral and ectodermal dysplasia characterized by short ribs, polydactyly, growth retardation, and ectodermal and heart defects. It is a rare disease with approximately 150 cases reported worldwide. The exact prevalence is unknown, but the syndrome seems more common among the Amish community. Prenatal abnormalities (that may be detected by ultrasound examination) include narrow thorax, shortening of long bones, hexadactyly and cardiac defects. After birth, cardinal features are short stature, short ribs, polydactyly, and dysplastic fingernails and teeth. Heart defects, especially abnormalities of atrial septation, occur in about 60% of cases. Cognitive and motor development is normal. This rare condition is inherited as an autosomal recessive trait with variable expression. Mutations of the EVC1 and EVC2 genes, located in a head to head configuration on chromosome 4p16, have been identified as causative. EVC belongs to the short rib-polydactyly group (SRP) and these SRPs, especially type III (Verma-Naumoff syndrome), are discussed in the prenatal differential diagnosis. Postnatally, the essential differential diagnoses include Jeune dystrophy, McKusick-Kaufman syndrome and Weyers syndrome. The management of EVC is multidisciplinary. Management during the neonatal period is mostly symptomatic, involving treatment of the respiratory distress due to narrow chest and heart failure. Orthopedic follow-up is required to manage the bones deformities. Professional dental care should be considered for management of the oral manifestations. Prognosis is linked to the respiratory difficulties in the first months of life due to thoracic narrowness and possible heart defects. Prognosis of the final body height is difficult to predict. PMID:17547743

  6. Remelting and Remobilization in a Magmatic Arc: the St Peter Suite, South Australia

    NASA Astrophysics Data System (ADS)

    Symington, Neil; Weinberg, Roberto; Hasalová, Pavlina

    2014-05-01

    Thermo-mechanical models of magmatic arcs suggest that intermittent intrusion of magma batches should lead to remelting and remobilization of earlier intrusive rocks as a result of fluctuations in temperature and water content. However, examples of remelting and remobilization of earlier intrusive rocks, formed during arc-building, are surprisingly rare. We investigate the evolution of magmatic rocks of the Palaeoproterozoic St Peter Suite, in the Gawler Craton, South Australia. This suite records multiple intrusions, magma hybridization, and the remelting and remobilization of these intrusions to form migmatites and newly-formed leucocratic magmas. In this paper we detail first how multiple magma batches interact with one another as liquids and mushes during syn-magmatic deformation phases, and then detail the nature of migmatites resulting from anatexis of these same magmatic rocks and the resulting channel ways that allowed for magma remobilization. LA-ICP/MS U/Pb zircon dating yielded crystallization ages of 1647±12 Ma for an early diorite-to-granite suite, and 1604±12 Ma for a later magmatic suite of broadly similar composition. Both these suites underwent anatectic events. Titanite from late-formed leucosomes found within D2 shear zones in the older suite, yielded SHRIMP U/Pb age of 1605±7 Ma, within error of the age of the younger suite. We therefore infer that intrusion, crystallization and remelting/remobilization of this younger suite of rocks occurred within 10-15 M.yr. Thus, the St Peter Suite exposures record many of the key processes expected in arcs, including the prediction that early intrusive arc rocks remelt to form younger more fractionated magmas.

  7. Influence of depositional environment and diagenesis on gas reservoir properties in St. Peter Sandstone, Michigan basin

    SciTech Connect

    Harrison, W.B. III; Turmelle, T.M.; Barnes, D.A.

    1987-05-01

    The St. Peter Sandstone in the Michigan basin subsurface is rapidly becoming a major exploration target for natural gas. This reservoir was first proven with the successful completion of the Dart-Edwards 7-36 (Falmouth field, Missaukee County, Michigan) in 1981. Fifteen fields now are known, with a maximum of three producing wells in any one field. The production from these wells ranges from 1 to more than 10 MMCFGD on choke, with light-gravity condensate production of up to 450 b/d. Depth to the producing intervals ranges from about 7000 ft to more than 11,000 ft. The St. Peter Sandstone is an amalgamated stack of shoreface and shelf sequences more than 1100 ft in thickness in the basin center and thinning to zero at the basin margins. Sandstone composition varies from quartzarenite in the coarser sizes to subarkose and arkose in the finer sizes. Thin salty/shaly lithologies and dolomite-cemented sandstone intervals separate the porous sandstone packages. Two major lithofacies are recognized in the basin: a coarse-grained, well-sorted quartzarenite with various current laminations and a fine-grained, more poorly sorted subarkose and arkose with abundant bioturbation and distinct vertical and horizontal burrows. Reservoir quality is influenced by original depositional and diagenetic fabrics, but there is inversion of permeability and porosity with respect to primary textures in the major lithofacies. The initially highly porous and permeable, well-sorted, coarser facies is now tightly cemented with syntaxial quartz cement, resulting in a low-permeability, poor quality reservoir. The more poorly sorted, finer facies with initially lower permeabilities did not receive significant fluid flux until it passed below the zone of quartz cementation. This facies was cemented with carbonate which has subsequently dissolved to form a major secondary porosity reservoir.

  8. The Global Food Crisis: Causes and Solutions. Statement of Peter McPherson before the Senate Foreign Relations Committee

    ERIC Educational Resources Information Center

    National Association of State Universities and Land-Grant Colleges, 2008

    2008-01-01

    This paper presents Peter McPherson's statement before the Senate Foreign Relations Committee. He begins by saying that people have an immediate problem that must be addressed, hopefully in a way that does not complicate long-term solutions. They also have a long-term and more complicated agricultural problem that the world has neglected over many…

  9. Writing the True Self: Case Studies of Eng 101 Students Responding to a Peter Elbow-Inspired Curriculum

    ERIC Educational Resources Information Center

    Stansell, Jon W.

    2012-01-01

    My fulfillment in life comes through helping others develop their potential, work through their troubles, and follow their dreams. I have found that my college students embrace this aspect as I teach them expressive, author-involved writing. Peter Elbow's work asserts that this type of writing fits into his theory of personal development,…

  10. Communication; A Discussion at the Nobel Conference (5th, Gustavus Adolphus College, St. Peter, Minnesota, January 8-9, 1969).

    ERIC Educational Resources Information Center

    Roslansky, John D., Ed.

    This book consists of five lectures on communication given at the fifth Nobel Conference. Leroy G. Augenstein explores the positive and negative consequences of man's increasing capacity to manipulate and control the human mind. Peter Marler demonstrates that all the elements necessary for a communication system to qualify as a language exist…

  11. Serials Management in the Electronic Era: Papers in Honor of Peter Gellatly, Founding Editor of "The Serials Librarian."

    ERIC Educational Resources Information Center

    Cole, Jim, Ed.; Williams, James W., Ed.

    This book assesses progress and technical changes in the field of serials management and anticipates future directions and challenges for librarians. The book consists of 18 chapters: (1) "Introduction" (Jim Cole and James W. Williams); (2) "Peter Gellatly--Editor with a Deft Touch" (Ruth C. Carter); (3) "The "Deseret News" Web Edition" (Stewart…

  12. Peter Fensham--Head, Heart and Hands (on) in the Service of Science Education and Social Equity and Justice

    ERIC Educational Resources Information Center

    Gunstone, Richard

    2009-01-01

    When Peter Fensham was appointed to the new Chair of Science Education at Monash University in 1967 he was the first Professor of Science Education in Australia, and, we think, may well have been the first such professor anywhere in the world outside USA. Over the subsequent 40+ years he has made/still makes remarkable and diverse contributions to…

  13. Pratt & Whitney Advanced Ducted Propulsor (ADP) Engine Test in 40x80ft w.t.: Engineers Peter

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Pratt & Whitney Advanced Ducted Propulsor (ADP) Engine Test in 40x80ft w.t.: Engineers Peter Zell (left) and Dr Clifton Horne (right) are shown preparing a laser light sheet for a flow visualization test. Shown standing in the nacelle of the ADP is John Girvin, senior test engineer for Pratt & Whitney.

  14. 76 FR 13271 - Gulf & Ohio Railways, Inc., H. Peter Claussen and Linda C. Claussen-Continuance in Control...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-10

    ... and published in the Federal Register (75 FR 63,533). The exemption became effective on October 31... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Surface Transportation Board Gulf & Ohio Railways, Inc., H. Peter Claussen and Linda C....

  15. Teaching, Learning and Education in Late Modernity: The Selected Works of Peter Jarvis. World Library of Educationalists

    ERIC Educational Resources Information Center

    Jarvis, Peter

    2011-01-01

    Professor Peter Jarvis has spent over 30 years researching, thinking and writing about some of the key and enduring issues in education. He has contributed well over 30 books and 200 papers and chapters in books on learning theory, adult education and learning, continuing professional education, nurse education, primary school education, distance…

  16. Pratt & Whitney Advanced Ducted Propulsor (ADP) Engine Test in 40x80ft w.t.: Engineers Peter

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Pratt & Whitney Advanced Ducted Propulsor (ADP) Engine Test in 40x80ft w.t.: Engineers Peter Zell (left) and Dr Clifton Horne (right) are shown preparing for a laser light sheet for a flow visualization test. Shown standing in the nacelle of the ADP is John Girvin, senior test engineer for Pratt & Whitney.

  17. The Good, the Worthwhile and the Obligatory: Practical Reason and Moral Universalism in R. S. Peters' Conception of Education

    ERIC Educational Resources Information Center

    Martin, Christopher

    2009-01-01

    Peters' account of the moral life and the conception of practical reason that informed it reflects a sophisticated moral universalism. However, attempts to extend a similarly sophisticated universalism into our understanding of education are not as well received. Yet, such a project is of clear contemporary relevance given the pressure put on…

  18. A Dena'ina Legacy. K'tl'egh'i Sukdu. The Collected Writings of Peter Kalifornsky.

    ERIC Educational Resources Information Center

    Kalifornsky, Peter; Kari, James, Ed.; Boraas, Alan, Ed.

    This collection of writings was compiled over a 19-year period (1972-91) by the last writer and one of the last storytellers of the Kenai dialect of Dena'ina (Tanaina) language of Cook Inlet, Alaska. Peter Kalifornsky is a literary artist and scholar born in 1911. The 147 writings are organized in eight chapters, with a prelude containing two…

  19. Saving Time and Money in Michigan: Peter J. Young Talks about Professional Development, Parent Communication, Funding, and Partnerships

    ERIC Educational Resources Information Center

    Branzburg, Jeffrey

    2007-01-01

    This article presents an interview with Peter J. Young, Director of Technology at Rockford Public Schools in Michigan. In the interview, Young talked about how his district has done a lot more automation to integrate its disparate systems. He also discussed how they streamline their systems, how parents and community benefit from these efforts,…

  20. Implementation of Linus Programme Based on the Model of Van Meter and Van Horn

    ERIC Educational Resources Information Center

    Sani, Nazariyah bt; Idris, Abdul Rahman

    2013-01-01

    The purpose of this study is to identify the understanding of school leaders on the implementation of LINUS programme that based on the features contained in the Implementation Model of Van Meter and Van Horn (1975). The study was carried out in the form of qualitative method and particularly, the multiple case studies that were conducted in four…

  1. English Translation of Selected Writings of Dina van Hiele-Geldof and Pierre M. van Hiele.

    ERIC Educational Resources Information Center

    Fuys, David, Ed.; And Others

    After observing secondary school students having great difficulty learning geometry in their classes, Dutch educators Pierre van Hiele and Dina van Hiele-Geldof developed a theoretical model involving five levels of thought development in geometry. It is the purpose of this monograph to present English translations of some significant works of the…

  2. Landward and eastward shift of Alaskan polar bear denning associated with recent sea ice changes

    USGS Publications Warehouse

    Fischbach, A.S.; Amstrup, Steven C.; Douglas, D.C.

    2007-01-01

    Polar bears (Ursus maritimus) in the northern Alaska region den in coastal areas and on offshore drifting ice. We evaluated changes in the distribution of polar bear maternal dens between 1985 and 2005, using satellite telemetry. We determined the distribution of maternal dens occupied by 89 satellite collared female polar bears between 137°W and 167°W longitude. The proportion of dens on pack ice declined from 62% in 1985–1994 to 37% in 1998–2004 (P = 0.044) and among pack ice dens fewer occurred in the western Beaufort Sea after 1998. We evaluated whether hunting, attraction to bowhead whale remains, or changes in sea ice could explain changes in den distribution. We concluded that denning distribution changed in response to reductions in stable old ice, increases in unconsolidated ice, and lengthening of the melt season. In consort, these changes have likely reduced the availability and quality of pack ice denning habitat. Further declines in sea ice availability are predicted. Therefore, we expect the proportion of polar bears denning in coastal areas will continue to increase, until such time as the autumn ice retreats far enough from shore that it precludes offshore pregnant females from reaching the Alaska coast in advance of denning.

  3. Science. [SITE 2002 Section].

    ERIC Educational Resources Information Center

    Roach, Linda Easley, Ed.

    This document contains the following papers on science from the SITE (Society for Information Technology & Teacher Education) 2002 conference: (1) "Color & Light: Design and Evaluation of a Multimedia-Case for Elementary Teacher-Education" (Peter Blijleven and Ellen van den Berg); (2) "Standards-Based Design of Technology-Integrated Science…

  4. Ellis-van Creveld syndrome: its history.

    PubMed

    Muensterer, Oliver J; Berdon, Walter; McManus, Chris; Oestreich, Alan; Lachman, Ralph S; Cohen, M Michael; Done, Stephen

    2013-08-01

    The story of Ellis-van Creveld syndrome is one of serendipity. By chance, Simon van Creveld and Richard Ellis purportedly met on a train and combined their independently encountered patients with short stature, dental anomalies and polydactyly into one landmark publication in 1940. They included a patient used in work published previously by Rustin McIntosh without naming McIntosh as a coauthor. This patient was followed radiologically by Caffey for nearly two decades. In 1964, Victor McKusick felt compelled to investigate a brief report in an obscure pharmaceutical journal on an unusual geographic cluster of short-statured Amish patients in Pennsylvania. This review highlights the lives of the individuals involved in the discovery of Ellis-van Creveld syndrome in their historic context. PMID:23754541

  5. Utilization of the St. Peter Sandstone in the Illinois Basin for CO2 Sequestration

    SciTech Connect

    Will, Robert; Smith, Valerie; Leetaru, Hannes

    2014-09-30

    This project is part of a larger project co-funded by the United States Department of Energy (US DOE) under cooperative agreement DE-FE0002068 from 12/08/2009 through 9/31/2014. The study is to evaluate the potential of formations within the Cambro-Ordovician strata above the Mt. Simon Sandstone as potential targets for carbon dioxide (CO2) sequestration in the Illinois and Michigan Basins. This report evaluates the potential injectivity of the Ordovician St. Peter Sandstone. The evaluation of this formation was accomplished using wireline data, core data, pressure data, and seismic data acquired through funding in this project as well as existing data from two additional, separately funded projects: the US DOE funded Illinois Basin – Decatur Project (IBDP) being conducted by the Midwest Geological Sequestration Consortium (MGSC) in Macon County, Illinois, and the Illinois Industrial Carbon Capture and Sequestration (ICCS) Project funded through the American Recovery and Reinvestment Act (ARRA), which received a phase two award from DOE. This study addresses the question of whether or not the St. Peter Sandstone may serve as a suitable target for CO2 sequestration at locations within the Illinois Basin where it lies at greater depths (below the underground source of drinking water (USDW)) than at the IBDP site. The work performed included numerous improvements to the existing St. Peter reservoir model created in 2010. Model size and spatial resolution were increased resulting in a 3 fold increase in the number of model cells. Seismic data was utilized to inform spatial porosity distribution and an extensive core database was used to develop porosity-permeability relationships. The analysis involved a Base Model representative of the St. Peter at “in-situ” conditions, followed by the creation of two hypothetical models at in-situ + 1,000 feet (ft.) (300 m) and in-situ + 2,000 ft. (600 m) depths through systematic depthdependent adjustment of the Base Model

  6. Selection of wolf dens in relation to winter territories in northeastern Minnesota

    USGS Publications Warehouse

    Ciucci, P.; Mech, L.D.

    1992-01-01

    Locations of wolf (Canus lupus) dens in the Superior National Forest in northeastern Minnesota from 1969 through 1988 were analyzed in relation to winter territories. Dens situated within the central 60% of the territories were randomly located relative to territory centers. However, only 10.5% (2) of the dens were located within a 1-km-wide strip inside the territory boundaries, indicating possible avoidance of neighboring packs. A negative relationship (r2 = 0.27; P 1 year, and possibly the availability of a stable food source helped determine den location.

  7. HL-10 on lakebed with Jerauld R. Gentry, Peter Hoag, John A. Manke, and Bill Dana

    NASA Technical Reports Server (NTRS)

    1969-01-01

    The four principal HL-10 pilots are seen here with the lifting body aircraft. They are, left to right; Air Force Major Jerauld R. Gentry, Air Force test pilot Peter Hoag, and NASA pilots John A. Manke and Bill Dana. All are wearing the pressure suits needed for flying above 50,000 feet. The HL-10 was one of five heavyweight lifting-body designs flown at NASA's Flight Research Center (FRC--later Dryden Flight Research Center), Edwards, California, from July 1966 to November 1975 to study and validate the concept of safely maneuvering and landing a low lift-over-drag vehicle designed for reentry from space. Northrop Corporation built the HL-10 and M2-F2, the first two of the fleet of 'heavy' lifting bodies flown by the NASA Flight Research Center. The contract for construction of the HL-10 and the M2-F2 was $1.8 million. 'HL' stands for horizontal landing, and '10' refers to the tenth design studied by engineers at NASA's Langley Research Center, Hampton, Va. After delivery to NASA in January 1966, the HL-10 made its first flight on Dec. 22, 1966, with research pilot Bruce Peterson in the cockpit. Although an XLR-11 rocket engine was installed in the vehicle, the first 11 drop flights from the B-52 launch aircraft were powerless glide flights to assess handling qualities, stability, and control. In the end, the HL-10 was judged to be the best handling of the three original heavy-weight lifting bodies (M2-F2/F3, HL-10, X-24A). The HL-10 was flown 37 times during the lifting body research program and logged the highest altitude and fastest speed in the Lifting Body program. On Feb. 18, 1970, Air Force test pilot Peter Hoag piloted the HL-10 to Mach 1.86 (1,228 mph). Nine days later, NASA pilot Bill Dana flew the vehicle to 90,030 feet, which became the highest altitude reached in the program. Some new and different lessons were learned through the successful flight testing of the HL-10. These lessons, when combined with information from it's sister ship, the M2-F2/F3

  8. Astronaut James van Hoften working with Syncom IV-3 satellite

    NASA Technical Reports Server (NTRS)

    1985-01-01

    Astronaut James D. van Hoften gives a shove to the previously troubled Syncom IV-3 communications satellite. Dr. van Hoften stands on a foot restraint/extension to the remote manipulator system (RMS) arm.

  9. Peter Andreas Hansen and the astronomical community - a first investigation of the Hansen papers. (German Title: Peter Andreas Hansen und die astronomische Gemeinschaft - eine erste Auswertung des Hansen-Nachlasses. )

    NASA Astrophysics Data System (ADS)

    Schwarz, Oliver; Strumpf, Manfred

    The literary assets of Peter Andreas Hansen are deposited in the Staatsarchiv Hamburg, the Forschungs- und Landesbibliothek Gotha and the Thüringer Staatsarchiv Gotha. They were never systematically investigated. We present here some results of a first evaluation. It was possible to reconstruct the historical events with regard to the maintenance of the Astronomische Nachrichten and the Altona observatory in 1854. Hansen was a successful teacher for many young astronomers. His way of stimulating the evolution of astronomy followed Zach's tradition.

  10. Post-den emergence behavior of polar bears (Ursus maritimus) in Northern Alaska

    USGS Publications Warehouse

    Smith, T.S.; Partridge, S.T.; Amstrup, Steven C.; Schliebe, S.

    2007-01-01

    We observed polar bear (Ursus maritimus) maternity den sites on Alaska’s North Slope in March 2002 and 2003 in an effort to describe bears’ post-den emergence behavior. During 40 sessions spanning 459 h, we observed 8 adults and 14 dependent cubs outside dens for 37.5 h (8.2% of total observation time). There was no significant difference between den emergence dates in 2002 (mean = 15 Mar ± 4.1 d) and 2003 (mean = 21 Mar ± 2.1 d). Following initial den breakout, polar bears remained at their den sites for 1.5 to 14 days (mean = 8.1 ± 5.1 d). The average length of stay in dens between emergent periods was significantly shorter in 2002 (1.79 h) than in 2003 (4.82 h). While outside, adult bears were inactive 49.5% of the time, whereas cubs were inactive 13.4% of the time. We found no significant relationships between den emergence activity and weather. Adult polar bears at den sites subjected to industrial activity exhibited significantly fewer bouts of vigilance than denned bears in undisturbed areas (t = -5.5164, df = 4, p= 0.00). However, the duration of vigilance behaviors at sites near industrial activity was not significantly shorter than at the other sites studied (t = -1.8902, df = 4, p = 0.07). Results for these bears were within the range of findings in other studies of denned polar bears.

  11. The Forced van der Pol Equation

    ERIC Educational Resources Information Center

    Fay, Temple H.

    2009-01-01

    We report on a study of the forced van der Pol equation x + [epsilon](x[superscript 2] - 1)x + x = F cos[omega]t, by solving numerically the differential equation for a variety of values of the parameters [epsilon], F and [omega]. In doing so, many striking and interesting trajectories can be discovered and phenomena such as frequency entrainment,…

  12. Brown-Vialetto-Van Laere syndrome.

    PubMed

    Francis, D A; Ponsford, J R; Wiles, C M; Thomas, P K; Duchen, L W

    1993-02-01

    The clinical and pathological findings of a male with the Brown-Vialetto-Van Laere syndrome are described. This rare and fatal affection of the nervous system involves mainly the brain stem with the prominent and early manifestation of sensorineural deafness. Increased awareness and documentation of this disorder has added information on the mode of inheritance. PMID:8474605

  13. Obituary for Jan van der Pers

    Technology Transfer Automated Retrieval System (TEKTRAN)

    After a short but valiant struggle against cancer, Jan van der Pers died on 29 April, 2006 in the hospital in Hilversum, The Netherlands, close to his home. Our conversations with Jan during the last months of his life showed the remarkable strength and positive attitude typical of him. Discussions...

  14. Van Helps Schools Select the Right Computer.

    ERIC Educational Resources Information Center

    Staples, Betsy

    1981-01-01

    Guidelines designed to aid in a systematic approach to the selection of hardware and software for classroom use are presented. This information is a portion of the information provided by a Multi Media Training Van supported by the Pennsylvania Department of Education. (MP)

  15. Passenger Vans: A Transportation Concern for Camps.

    ERIC Educational Resources Information Center

    Gentle, Don; Gordon, Harold; Schainman, Steve

    2002-01-01

    In April 2002, the National Transportation Safety Board reissued a cautionary warning about the high accident potential of 15-passenger vans; some states have prohibited their use for transporting children. Three camp directors discuss legal and cost considerations for camps, possible alternative transportation, additional staff training needs,…

  16. Q & A with Carmella Van Vleet

    ERIC Educational Resources Information Center

    Curriculum Review, 2008

    2008-01-01

    This article presents an interview with Carmella Van Vleet, a former teacher and educational speaker. She has written family humor and parenting articles, and is also the author of "How to Handle School Snafus," "Great Ancient Egypt Projects You Can Build Yourself" and "Amazing Ben Franklin Inventions You Can Build Yourself." In this interview,…

  17. Van Hiele Levels of Geometric Thought Revisited.

    ERIC Educational Resources Information Center

    Teppo, Anne

    1991-01-01

    Compared are the van Hiele levels of geometric thinking and the geometry curriculum recommended by the National Council of Teachers of Mathematics Curriculum and Evaluation Standards for School Mathematics. Activities which illustrate the various levels are provided by grade level with procedures. (CW)

  18. van Maanen, Adriaan (1884-1947)

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    Dutch astronomer, became a member of the Mount Wilson staff, and studied the rotation of spiral nebulae as a means to establish their distances. His detection of rotational motions was illusory and misleadingly suggested that they were relatively nearby. Through its proper motion and parallax, he discovered the white dwarf van Maanen's star....

  19. Research and the Bernard van Leer Foundation.

    ERIC Educational Resources Information Center

    Wall, W. D.

    1978-01-01

    Outlines Bernard van Leer Foundation sponsorship of action programs and research studies of child development in 25 countries. The problems and possibilities of such work are discussed from the viewpoint of evaluation and the contribution which can be made to the behavioral sciences--notably to comparative child development. (Author/RH)

  20. 77 FR 14583 - Notice to Manufacturers of Alternative Fuel Vans

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-12

    ... Federal Aviation Administration Notice to Manufacturers of Alternative Fuel Vans AGENCY: Federal Aviation Administration (FAA), U.S. DOT. ACTION: Notice to Manufacturers of Alternative Fuel Vans. SUMMARY: Projects... manufacturers of alternative fuel vans. This notice requests information from manufacturers of alternative...

  1. The Selection of a Van Lift or a Scooter.

    ERIC Educational Resources Information Center

    Stevens, John H.

    1990-01-01

    This newsletter issue describes 3-wheeled scooters and van lifts that can assist a person with a disability to drive independently or have access to transportation. The section on van lifts compares hydraulic lifts and electric lifts, lists manufacturers, and offers an "assessment quiz" outlining factors to consider in selecting a van lift. In the…

  2. van Hiele Levels and Achievement in Writing Geometry Proofs.

    ERIC Educational Resources Information Center

    Senk, Sharon L.

    1989-01-01

    Secondary geometry students were tested for van Hiele level of thinking, geometry knowledge and achievement, and proof-writing achievement. Proof-writing achievement correlated significantly with van Hiele level entering geometry knowledge and geometry achievement. The predictive validity of the van Hiele model was supported. (Author/DC)

  3. Controls on deposition of the St. Peter Sandstone (Middle-Late Ordovician), Michigan basin

    SciTech Connect

    Nadon, G.C.; Simo, A.; Byers, C.W.; Dott, R.H, Jr. )

    1991-08-01

    The St. Peter Sandstone (Middle-late Ordovician) of the Michigan basin represents an approximately 10-m.y. interval of clastic deposition in an otherwise carbonate-dominated Ordovician succession. This interval, up to 320 m thick, also coincides with a change in basin configuration from the nearly circular depocenter of the underlying Shakopee Formation to an east-west elongate trough situated west to Saginaw Bay. Interpretation of well logs and core from throughout the basin indicates that the clastics are composed of 20-25 sequences upper shoreface to tidal-flat environments. The sequences are interbedded with heavily bioturbated, shaly, lower shoreface sandstones (1-14 m thick) and, in the central and southeastern parts of the basin, with carbonate shales, stromatolites, and oolitic grain-stones (2-39 m thick). The eastern and southeastern margins of the basin contain the thickest carbonate accumulations. Hydrocarbons fields are located over structural highs formed by reactivation of basement structures. Detailed comparison of well logs within field shows that sedimentary cycles thin over the structures as a result of the local reduction in the formation of accommodation space by syndepositional movements on the faults. The presence of thick carbonates along the southeastern margin of the basin is a result of the combination of distance form the clastic source and the episodic formation of accommodation space by syndepositional normal faulting along the basin margin.

  4. Reminiscences of Sir Peter Medawar: in hope of antigen-specific transplantation tolerance.

    PubMed

    Simpson, Elizabeth

    2004-12-01

    Peter Medawar's career in medical research (he always described himself as a medical research scientist) began as a student of zoology in Oxford. He obtained a first class degree in 1936, aged 21, and undertook postgraduate studies with Florey. His work was anchored in a broad field; he was adept at addressing novel questions in the context of prior ideas and knowledge. His earlier interest in growth, driven as much by mathematics as biology, gave way to transplantation at the beginning of World War II, treatment of burns patients being the driver. He interpreted the results of grafting autologous and allogeneic human skin, observed clinically and microscopically, as immunological; he identified accelerated donor-specific reactions to subsequent grafts as 'second set', and described cell (lymphocyte) mediated infiltration of allo- but not auto-grafts following initial vascularization, both in the patient context and in experimental animals. He became intrigued by the consequences of hematopoietic chimerism, from which his landmark discoveries on the induction of transplantation tolerance derive. These results, his interpretation and dissemination of them, gave hope to transplant surgeons that donor-specific transplant tolerance would be achievable. Many immunosuppressive drugs later, we are now reapproaching this hope, from various angles. PMID:15575894

  5. Cold-Air-Pool Structure and Evolution in a Mountain Basin: Peter Sinks, Utah

    SciTech Connect

    Clements, Craig B.; Whiteman, Charles D.; Horel, John D.

    2003-06-01

    The evolution of potential temperature and wind structure during the buildup of nocturnal cold-air pools was investigated during clear, dry, September nights in Utah's Peter Sinks basin, a 1-km-diameter limestone sinkhole that holds the Utah minimum temperature record of -56 C. The evolution of cold-pool characteristics depended on the strength of prevailing flows above the basin. On an undisturbed day, a 30 C diurnal temperature range and a strong nocturnal potential temperature inversion (22 K in 100 m) were observed in the basin. Initially, downslope flows formed on the basin sidewalls. As a very strong potential temperature jump (17 K) developed at the top of the cold pool, however, the winds died within the basin and over the sidewalls. A persistent turbulent sublayer formed below the jump. Turbulent sensible heat flux on the basin floor became negligible shortly after sunset while the basin atmosphere continued to cool. Temperatures over the slopes, except for a 1 to 2-m-deep layer, became warmer than over the basin center at the same altitude. Cooling rates for the entire basin near sunset were comparable to the 90 W m-2 rate of loss of net longwave radiation at the basin floor, but these rates decreased to only a few watts per square meter by sunrise. This paper compares the observed cold-pool buildup in basins with inversion buildup in valleys.

  6. [Peter Plett and other discoverers of cowpox vaccination before Edward Jenner].

    PubMed

    Plett, Peter C

    2006-01-01

    Before Edward Jenner tested the possibility of using the cowpox vaccine as an immunisation for smallpox in humans in 1796, at least six people had done the same several years earlier. However, the findings of these six people regarding the cowpox vaccination are either hardly known or have even been forgotten. For the first time, the originally scattered information on the procedures used by these six people has been gathered and will be presented in this article. Detailed attention will be given to the works of the teacher Peter Plett (1766-1823), the only one to recognize the importance of his discovery for mankind. In 1790 and 1791/92, Plett reported his findings to the Medical Faculty of the University of Kiel. The faculty disregarded Plett's reports by neither responding to them nor changing their methods of immunisation, as the faculty at that time was still in favour of variolation. This article contains the available information and references concerning Plett's discovery, including the entire sources from 1802 and 1815 describing his findings. PMID:17338405

  7. Acute toxic effects of fenpyroximate acaricide on Guppy (Poecilia reticulata Peters, 1859).

    PubMed

    Doğan, Nesli; Yazıcı, Zehra; Şişman, Turgay; Aşkin, Hakan

    2013-09-01

    Fenpyroximate (FP), an acaricide, is widely used in the prevention of acarids (mites) in fruit plant gardens. In this study, the acute toxic effects of different concentrations of FP were investigated using adult guppy (Poecilia reticulata Peters, 1859). Guppy adults were exposed to a range of FP concentrations (25, 50, 75, 100, 125, and 150 µg/L) during 48 h. Static method, which is one of the acute toxicity experiments, has been used in this study. According to probit analysis, the 48-h median lethal concentration (LC50) value of FP at 26°C was found to be 72.821 µg/L. Sublethal exposures were predetermined based on 48-h LC50 value. Guppies were exposed to low concentrations (15, 25, and 50 µg/L) of FP for 48 h. Signs of paralysis and behavior deformations were monitored every 12 h in a number of live and dead adults. Low concentrations of FP were also responsible for erratic swimming, loss of equilibrium, and being lethargic. Liver histology revealed several pathological damages including congestion, picnotic nucleus, sinusoidal dilatation, increase in melanomacrophagic centers, and endothelial degeneration. Finally, the toxicity test results provided 48-h LC50 value for FP, and low concentrations of FP can be highly detrimental to guppy adults with clear evidence of behavioral and histologic effects. PMID:22508399

  8. "Pop" psychoanalysis, kitsch, and the "as if" theater: further notes on Peter Shaffer's Equus.

    PubMed

    Gifford, S

    1976-01-01

    This paper is intended as an examination of Dr. Stamm's (1975) paper and of Dr. Jules Glenn's discussion of Peter Shaffer's previous work. Its premise is the futility of subjecting Equus to a traditional psychoanalytic investigation, as a product of the playwright's unconscious, when the play represents a skillful, highly conscious use of analytic cliches to manipulate the audience. This phenomenon, however, and the play's great popularity prompt some reflections on the nature of kitsch, or false art, and its differences from authentic drama. The experience of kitsch can be identified when the spectator feels coerced by exaggerated, unconvincing theatrical devices, and fails to experience genuine empathy with the characters in a play. In the experience of authentic tragedy there is some element of voluntary surrender, of suspension of disbelief with full consent of will, as in the Aristotelian concept of catharsis. Shaffer's play is discussed as an illustration of this distinction and its relation to pseudoemotionality, the impostor syndrome, and the "as if" personality. In conclusion, the play's failure to evoke a genuine emotional response is explained by interpreting Equus as an "as if" tragedy. PMID:986375

  9. A psychoanalytic reading of Peter Høeg's novel Miss Smilla's Feeling for Snow.

    PubMed

    Gammelgaard, J

    2001-02-01

    The author presents a psychoanalytic reading of the Danish author Peter Høeg's masterpiece 'Miss Smilla's Feeling for Snow', focusing on the special linguistic style of the novel. Further, the author puts forward an interpretation of the heroine, seeing her as a literary example of female bisexuality. Investigating the heroine's fate, the author discusses Miss Smilla's phallic defence and identity. The narrative technique in Høeg's novel is analysed through Lacan's concepts of the Real, the Imaginary and the Symbolic. The main figure is interpreted as an imaginary example of female bisexuality. Miss Smilla has neither an unambiguous gender identity nor ethnicity. The heroine is pictured in a conflict between two cultures: the Greenlandish and the western European, and her bisexuality both reflects this and is part of it. The author proposes to interpret a significant memory from Smilla's early childhood as an example of a castration phantasy, which retroactively gives new significance to the little girl's pre-oedipal frustration. PMID:11234104

  10. [Catering services bases in the Russian army under military regulation of Peter the Great].

    PubMed

    Konyshev, I S; adamenko, A M; Koshelev, V P

    2014-01-01

    At Peter I the regular army was organized and the system of target state deliveries to troops of the food is created. Provisioning and fodder was normalized as portion and ration. Portion was contained the products forpeoplefood, and ration - fodder for horses food who were used by the serviceman. Portion and ration unit was identical to all categories of the military personnel. Difference in food level consisted in that, how many portions and rations serviceman received. Up to the end of existence of Russian army in 1918 in each rota there were contractor and the cook who were engaged in foodstuff and cooking under sergeant-major and one of rota officers supervision. According to the Charter it was necessary to carry with respect and attention to officers and soldiers, their needs, including in the field of supply and catering services and providing with the food: Despite the lack of scientific justification, soldiers' nutrition was sufficient to provide fighting capacity of the Russian army. PMID:25816632

  11. Peter Fensham—head, heart and hands (on) in the service of science education and social equity and justice

    NASA Astrophysics Data System (ADS)

    Gunstone, Richard

    2009-06-01

    When Peter Fensham was appointed to the new Chair of Science Education at Monash University in 1967 he was the first Professor of Science Education in Australia, and, we think, may well have been the first such professor anywhere in the world outside USA. Over the subsequent 40+ years he has made/still makes remarkable and diverse contributions to science education research and practice, both within Australia and internationally (in, it seems, every `corner' of the globe). As founder of ASERA and of science education research in Australia, Peter is clearly the most obvious and central Key Figure to include in this special issue of CSSE about the Australasian Science Education Research Association.

  12. Lake Van Drilling Project 'PaleoVan' to be drilled in summer 2010

    NASA Astrophysics Data System (ADS)

    Litt, Thomas; Krastel, Sebastian; Anselmetti, Flavio; Kipfer, Rolf; Öcen, Sefer; Cagaty, Namik; Schmincke, Hans-Ulrich

    2010-05-01

    Lake Van is the fourth largest terminal lake in the world (volume 607 km3, area 3,570 km2, maximum depth 460 m), extending for 130 km WSW-ENE on the Eastern Anatolian High Plateau, Turkey. The annually-laminated sedimentary record of Lake Van promises to be an excellent palaeoclimate archive because it potentially yields a long and continuous continental sequence that covers several glacial-interglacial cycles (ca. 500 kyr). Therefore, Lake Van is a key site within the International Continental Scientific Drilling Program (ICDP) for the investigation of the Quaternary climate evolution in the Near East. Based on the high-resolution seismic data and multidisciplinary scientific work, it is planned to drill a series of sites in Lake Van in the frame of ICDP in summer 2010. The geochronological precision on a decadal or even annual scale will allow comparisons not only with astronomical cyclicity but also signals below the frequency of Milankovitch cycles, such as North Atlantic Oscillation, which may have also affected the past climate system of the eastern Mediterranean region. As a closed and saline lake, Lake Van reacts very sensitively to lake level changes caused by any alterations in the hydrological regime in response to climate change. Tephra layers, documented in short cores and also expected in the deep drill cores of Lake Van sediments, allow reconstructing larger volcanic events and environmental impacts. The short cores from Lake Van show also strong evidence of earthquake-triggered microfaults, interpreted as seismites. Similar features are expected to be found in the deeper sections. The unique setting of Lake Van, which records simultaneously the volcanic as well as the earthquake history, will also allow establishing possible coincidence between larger earthquakes and volcanic events. Preparation of the drilling campaign is almost finished and drilling is scheduled to start in July 2010.

  13. Evaluation of the Xpert vanA/vanB Assay Using Enriched Inoculated Broths for Direct Detection of vanB Vancomycin-Resistant Enterococci

    PubMed Central

    Arends, J. P.; Kampinga, G. A.; Ahmad, H. M.; Dijkhuizen, B.; van Barneveld, P.; Rossen, J. W. A.; Friedrich, A. W.

    2014-01-01

    Rapid and accurate detection of VRE (vancomycin-resistant enterococci) is required for adequate antimicrobial treatment and infection prevention measures. Previous studies using PCR for the detection of VRE, including Cepheid's Xpert vanA/vanB assay, reported accurate detection of vanA VRE; however, many false-positive results were found for vanB VRE. This is mainly due to nonenterococcal vanB genes, which can be found in the gut flora. Our goal was to optimize the rapid and accurate detection of vanB VRE and to improve the positive predictive value (PPV) by limiting false-positive results. We evaluated the use of the Xpert vanA/vanB assay on rectal swabs and on enriched inoculated broths for the detection of vanB VRE. By adjusting the cycle threshold (CT) cutoff value to ≤25 for positivity by PCR on enriched broths, the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were 96.9%, 100%, 100%, and 99.5% for vanB VRE, respectively. As shown in this study, CT values of ≤25 acquired from enriched broths can be considered true positive. For broths with CT values between 25 and 30, we recommend confirming the results by culture. CT values of >30 appeared to be true negative. In conclusion, this study shows that the Cepheid's Xpert vanA/vanB assay performed on enriched inoculated broths with an adjusted cutoff CT value is a useful and rapid tool for the detection of vanB VRE. PMID:25297325

  14. Theoretical Claims Necessitate Basic Research: Reply to Gawronski, Lebel, Peters, and Banse (2009) and Nosek and Greenwald (2009)

    ERIC Educational Resources Information Center

    De Houwer, Jan; Teige-Mocigemba, Sarah; Spruyt, Adriaan; Moors, Agnes

    2009-01-01

    The authors of this reply article note that B. Gawronski, E. P. LeBel, K. R. Peters, and R. Banse (2009) (a) expressed agreement in their comment with the analysis put forward in the target article (J. De Houwer, S. Teige-Mocigemba, A. Spruyt, & A. Moors, 2009) and (b) pointed to a further implication for the way in which the implicitness of a…

  15. Wildlife and Wildlife Habitat Loss Assessment at Green Peter-Foster Project; Middle Fork Santiam River, Oregon, 1985 Final Report.

    SciTech Connect

    Noyes, J.H.

    1986-02-01

    A habitat based assessment was conducted of the US Army Corps of Engineers' Green Peter-Foster Dam and Reservoir Project on the Middle Fork Santiam River, Oregon, to determine losses or gains resulting from the development and operation of the hydroelectric related components of the project. Preconstruction, postconstruction, and recent vegetation cover types at the project site were mapped based on aerial photographs from 1955, 1972, and 1979, respectively. Vegetation cover types were identified within the affected area and acreages of each type at each period were determined. Eleven wildlife target species were selected to represent a cross-section of species groups affected by the project. An interagency team evaluated the suitability of the habitat to support the target species at each time period. An evaluation procedure which accounted for both the quantity and quality of habitat was used to aid in assessing impacts resulting from the project. The Green Peter-Foster Project extensively altered or affected 7873 acres of land and river in the Santiam River drainage. Impacts to wildlife centered around the loss of 1429 acres of grass-forb vegetation, 768 acres of shrubland, and 717 acres of open conifer forest cover types. Impacts resulting from the Green Peter-Foster Project included the loss of critical winter range for black-tailed deer and Roosevelt elk, and the loss of year-round habitat for deer, upland game birds, river otter, beaver, pileated woodpecker, and many other wildlife species. Bald eagle and osprey were benefited by an increase in foraging habitat. The potential of the affected area to support wildlife was greatly altered as a result of the Green Peter-Foster Project. Losses or gains in the potential of the habitat to support wildlife will exist over the life of the project.

  16. Polar bear maternal den habitat in the Arctic National Wildlife Refuge, Alaska

    USGS Publications Warehouse

    Durner, G.M.; Amstrup, Steven C.; Ambrosius, K.J.

    2006-01-01

    Polar bears (Ursus maritimus) give birth during mid-winter in dens of ice and snow. Denning polar bears subjected to human disturbances may abandon dens before their altricial young can survive the rigors of the Arctic winter. Because the Arctic coastal plain of Alaska is an area of high petroleum potential and contains existing and planned oil field developments, the distribution of polar bear dens on the plain is of interest to land managers. Therefore, as part of a study of denning habitats along the entire Arctic coast of Alaska, we examined high-resolution aerial photographs (n = 1655) of the 7994 km2 coastal plain included in the Arctic National Wildlife Refuge (ANWR) and mapped 3621 km of bank habitat suitable for denning by polar bears. Such habitats were distributed uniformly and comprised 0.29% (23.2 km2) of the coastal plain between the Canning River and the Canadian border. Ground-truth sampling suggested that we had correctly identified 91.5% of bank denning habitats on the ANWR coastal plain. Knowledge of the distribution of these habitats will help facilitate informed management of human activities and minimize disruption of polar bears in maternal dens.

  17. Kin selection in den sharing develops under limited availability of tree hollows for a forest marsupial

    PubMed Central

    Banks, Sam C.; Lindenmayer, David B.; McBurney, Lachlan; Blair, David; Knight, Emma J.; Blyton, Michaela D. J.

    2011-01-01

    Animal social behaviour is not static with regard to environmental change. Flexibility in cooperative resource use may be an important response to resource decline, mediating the impacts of resource availability on fitness and demography. In forest ecosystems, hollow trees are key den resources for many species, but are declining worldwide owing to forestry. Altered patterns of den sharing may mediate the effects of the decline of this resource. We studied den-sharing interactions among hollow-dependent Australian mountain brushtail possums to investigate how spatial variation in hollow tree availability affects resource sharing and kin selection. Under reduced den availability, individuals used fewer dens and shared them less often. This suggests increased territoriality in the presence of resource competition. Further, there was a switch from kin avoidance to kin preference with decreasing hollow tree availability. This was driven primarily by a change in den sharing among siblings. The inclusive fitness benefits of den sharing with kin are likely to increase under resource-limiting conditions, but are potentially outweighed by the benefits of associating with non-relatives (avoidance of inbreeding or pathogen transmission) where dens are abundant. We discuss how predictions from social evolutionary theory can contribute to understanding animal responses to landscape change. PMID:21288953

  18. Den site activity patterns of adult male and female swift foxes, Vulpes velox, in Northwestern Texas

    USGS Publications Warehouse

    Lemons, P.R.; Ballard, W.B.; Sullivan, R.M.; Sovada, M.A.

    2003-01-01

    Activity of Swift Foxes (Vulpes velox) at den sites was studied in northwestern Texas during pup rearing seasons in 2000 and 2001 to determine role of males in parental care. Twenty-four percent of radio-collared females with a potential to breed successfully raised pups to eight weeks of age. We intensively monitored presence and absence of male and female Swift Foxes at two den sites each year. Females were present >2.6 times more at den sites than males during the pup rearing season. Female and male Swift Foxes largely stayed at dens during diurnal hours and were active away from dens during nocturnal and crepuscular hours. Females and males spent 12.4% and 3.0% more time at dens before pups emerged, than after pups emerged, respectively. Following depredation of one male parent, the female spent 29% less time at the den site. Decrease in time spent at the den by the female following loss of her mate suggested that loss of one parent might severely impact recruitment of Swift Foxes. Our observations indicated that intense Coyote (Canis latrans) depredation may severely impact pup-rearing success as well as the parental care within Swift Fox family groups.

  19. Two new species of quill mites (Acari: Syringophilidae) associated with the Chestnut-fronted Helmetshrike Prionops scopifrons (Peters) (Passeriformes: Vangidae) in Kenya.

    PubMed

    Klimovičová, Miroslava; Skoracki, Maciej; Hromada, Martin

    2016-01-01

    Two new species of syringophilid mites collected from Prionops scopifrons (Peters) (Passeriformes: Vangidae) in Kenya are described: Neoaulonastus prionops sp. nov. and Picobia meru sp. nov. They are the first syringophilid records from birds of the family Vangidae. PMID:27470747

  20. Dens invaginatus in an impacted mesiodens: a morphological study.

    PubMed

    Cantín, M; Fonseca, G M

    2013-01-01

    Dens invaginatus (DI) is a dental anomaly originated from invagination of the enamel organ into the dental papilla, during odontogenesis. DI may be associated with other abnormalities such as dysmorphic mesiodens, and this unusual condition may be detected by chance on the conventional radiography. However, the three-dimensional nature and the exact morphological patterns of DI are impossible to appreciate from this method. We present a morphological study of impacted mesiodens in a 9-year-old girl, which the three coronal invaginations were detected only by Cone-Beam Computed Tomography (CBCT) in the pre-surgical examination. CBCT, radiographic and microscopic reproductions allow transfer of images to facilitate cooperation of working groups, examination as well as for teaching purposes. PMID:24322044

  1. Vector competence of Aedes albopictus and Aedes aegypti (Diptera: Culicidae) for the DEN2-FJ10 and DEN2-FJ11 strains of the dengue 2 virus in Fujian, China.

    PubMed

    Guo, Xiao-Xia; Li, Chun-Xiao; Zhang, Ying-Mei; Xing, Dan; Dong, Yan-De; Zhang, Heng-Duan; Qin, Cheng-Feng; Zhao, Tong-Yan

    2016-09-01

    Dengue is an acute, emerging, infectious disease transmitted by Aedes mosquitoes that has become a serious global public health problem. The DEN2-FJ10 and DEN2-FJ11 strains of the dengue 2 virus were originally isolated from the serum of a patient with dengue fever in Fujian Province, China, in 1999. Our data provide the first assessment of the vector competence of Aedes mosquitoes with respect to the DEN2-FJ10 and DEN2-FJ11 strains of the dengue virus. There were significant differences in the replication rates of these two viral strains in Aedes albopictus and Aedes aegypti (P<0.05); replication of the DEN2-FJ10 strain was greater in Ae. aegypti than in Ae. albopictus 5 days post infection whereas replication of the DEN2-FJ11 was greater in Ae. albopictus than in Ae. aegypti 7 days post infection. The replicative ability of the DEN2-FJ11 strain was greater than that of the DEN2-FJ10 strain in infected Ae. albopictus. In infected Ae. aegypti, rapid proliferation of the DEN2-FJ10 strain occurred earlier than in the DEN2-FJ11 strain. There were no significant differences in the midgut and salivary gland infection rates of Ae. albopictus and Ae. aegypti with respect to either viral strain. Although the DEN2-FJ10 and DEN2-FJ11 strains differ in their virulence to neonatal rats, there was no significant difference in the ability of either Ae. albopictus or Ae. aegypti to transmit the DEN2-FJ10 and DEN2-FJ10 strains of the dengue 2 virus (P>0.05). In summary, our results indicate that Ae. albopictus and Ae. aegypti mosquitoes are moderately competent vectors of the DEN2-FJ10 and DEN2-FJ11 strains of the dengue virus and provide the first evidence of the effect of these two viral strains on the vector competence of mosquitoes in China. PMID:27260668

  2. A dissection of the chapter "Tools for Research" in Peter Singer's Animal Liberation.

    PubMed

    Russell, S M; Nicoll, C S

    1996-02-01

    The book Animal Liberation, by philosopher Peter Singer, is frequently referred to as the bible of the animal liberation/rights movement(ALARM). Thus, Singer is regarded as a major moral standard-bearer of the ALARM. Some have suggested that his book provides "intellectual rigor" to the moral arguments for animals' equality with humans, which had previously been based largely on emotionalism and sentimentality. We have analyzed the contents of the chapter "Tools for Research" which criticizes the use of animals in biomedical research as well as for drug and product-safety testing. In order to discredit these practices, Singer "documents" his arguments with 138 "notes", some of which are to the same reference and others of which contain multiple references. Of the 132 difference references, we attempted to verify the accuracy of 49 of them. Of these, 16 (33%) were inaccurate or we could not find. In addition, Singer mischaracterizes the cited studies in various ways. He quotes selectively and out of context from numerous research projects. He never mentions the objectives of these projects, except occasionally when, in our opinion, he distorts or trivializes them. Singer also cites supposedly damning "evidence" published by other antivivisectionists, even though this "evidence" has been refuted in the literature. Singer supposedly embraces utilitarianism, a philosophy which holds that the harm done by a practice should be balanced against the gain realized from it. However, he makes virtually no attempt to consider objectively the benefits that have been realized from animal-based medical research and he greatly exaggerates the costs. To him, animal research is "all pain and no gain." We believe that Singer's moral arguments for animal equality are not convincing. The lack of objectivity and the reliance upon distortion and selective quotation that characterize Singer's "scholarship" are surprising when one considers that he presents himself as an ethicist and

  3. Geochemistry of dolomites in the St. Peter Sandstone of the Michigan Basin

    SciTech Connect

    Winter, B.L.; Johnson, C.M.; Valley, J.W. . Dept. of Geology and Geophysics)

    1992-01-01

    Quartz sandstone units in mid-continent sedimentary basins are considered to be major migration pathways for fluids throughout the history of such basins, possibly including connate and meteoric water, hydrocarbons, evaporite and basinal brines, and MVT ore-forming fluids. To gain an understanding of the fluid history of the Michigan Basin, the authors are investigating the dolomites in the St. Peter Sandstone. Based on petrography and lithofacies occurrence, they categorize the dolomites as: dolomite cement in quartz sandstone (DCS), replacive dolomite in carbonate-dominated intervals (RD), and fracture fill dolomite (FFD) associated with RD. RD and FFD display a linear covariation of mole %FeCO[sub 3] and Mn with Fe/Mn ratios increasing from 6 for bright orange luminescent RD to 11 for non-luminescent FFD. DCS display the highest %FeCO[sub 3] and no Fe-Mn correlation. DCS have higher ratios and SR concentrations than RD and FFD. Data for RD and FFD define two different, linear positive-sloping, Sr-87/Sr-86-%FeCO[sub 3] covariation trends. Samples with higher ratios and %FeCO[sub 3] have systematically lower [delta] O-18 values. Dolomites with Sr < 130ppm (mostly RD and FFD) follow the Sr-%MgCO[sub 3] trend defined by modern seawater dolomites; most of the DCS plot above this seawater dolomite trend. These data suggest that the RD and FFD precipitated from mid-Paleozoic seawater that progressively evolved in a basinal setting or mixed with an evolved basinal brine. DCS precipitated from a basinal brine that had interacted with rocks containing a significant amount of K-feldspar. The different correlation trends suggest heterogeneous water-rock interaction and isolated flow paths.

  4. Peters plus syndrome mutations disrupt a non-canonical ER quality control mechanism

    PubMed Central

    Vasudevan, Deepika; Takeuchi, Hideyuki; Johar, Sumreet Singh; Majerus, Elaine; Haltiwanger, Robert S.

    2014-01-01

    Background O-Fucose is added to cysteine-rich domains called Thrombospondin type 1 repeats (TSRs) by Protein O-fucosyltransferase 2 (POFUT2) and is elongated with glucose by β3-glucosyltransferase (B3GLCT). Mutations in B3GLCT result in Peters Plus Syndrome (PPS), an autosomal recessive disorder characterized by eye and other developmental defects. Although 49 putative targets are known, the function of the disaccharide and its role in PPS remain unexplored. Results Here we show that while POFUT2 is required for secretion of all targets tested, B3GLCT only affects the secretion of a subset, consistent with the observation that B3GLCT mutant phenotypes in PPS patients are less severe than embryonic lethal phenotypes of Pofut2-null mice. O-Glycosylation occurs co-translationally, as TSRs fold. Mass spectral analysis reveals that TSRs from mature, secreted protein are stoichiometrically modified with the disaccharide, while TSRs from protein still folding in the ER are partially modified, suggesting that O-glycosylation marks folded TSRs and promotes ER exit. In vitro unfolding assays demonstrate that fucose and glucose stabilize folded TSRs in an additive manner. In vitro refolding assays under redox conditions showed that POFUT2 recognizes, glycosylates, and stabilizes the folded form of TSRs, resulting in a net acceleration of folding. Conclusions While known ER quality control machinery rely on identifying and tagging unfolded proteins, we find that POFUT2 and B3GLCT mediate a non-canonical ER quality control mechanism that recognizes folded TSRs and stabilizes them by glycosylation. Our findings provide a molecular basis for the defects observed in PPS and potential targets that contribute to the pathology. PMID:25544610

  5. The 2007 Nobel Prize in Physics: Albert Fert and Peter Grünberg

    NASA Astrophysics Data System (ADS)

    Cros, Vincent; Fert, Albert; Sénéor, Pierre; Petroff, Frédéric

    GMR and spintronics take their roots in the pioneering work of Albert Fert around 1970 on the influence of the spin on the mobility of electrons in ferromagnetic materials [1]. After having experimentally demonstrated that, in a ferromagnetic metal, the electrons of opposite spin directions (spin up and spin down along the magnetization axis) carry different currents (as originally suggested by Mott), Fert worked out the well known two current model of the electrical conduction in ferromagnetic metals. He also showed that very large spin asymmetries of the conduction can be obtained by doping the ferromagnetic metal with impurities selected to scatter very differently the spin up and spin down electrons (iron or cobalt impurities in nickel, for example, scatter the spin down electrons 20 times more strongly than the spin up electrons). Moreover, some experiments of Fert on ternary alloys were already introducing the idea that he will exploit later to produce the GMR effects. He showed that the resistivity of a ternary alloy, for example N 1-x (A x-y ,B y ), is strongly enhanced if the scattering by the impurities A and B have inverse spin asymmetries. Replacing the impurities A and B by magnetic layers A and B, one equally expects a large enhancement of the resistivity when their magnetizations are in opposite directions, which the basic concept of the GMR. However, this concept can work only if the thickness of the layers is in the nanometer range. The fabrication of multilayers with thicknesses in this range became technologically possible in the mid-eighties and, in particular, the growth of magnetic multilayers by Molecular Beam Epitaxy (MBE) was developed in the groups of Albert Fert and Peter Grünberg.

  6. A note on evaluating VAN earthquake predictions

    NASA Astrophysics Data System (ADS)

    Tselentis, G.-Akis; Melis, Nicos S.

    The evaluation of the success level of an earthquake prediction method should not be based on approaches that apply generalized strict statistical laws and avoid the specific nature of the earthquake phenomenon. Fault rupture processes cannot be compared to gambling processes. The outcome of the present note is that even an ideal earthquake prediction method is still shown to be a matter of a “chancy” association between precursors and earthquakes if we apply the same procedure proposed by Mulargia and Gasperini [1992] in evaluating VAN earthquake predictions. Each individual VAN prediction has to be evaluated separately, taking always into account the specific circumstances and information available. The success level of epicenter prediction should depend on the earthquake magnitude, and magnitude and time predictions may depend on earthquake clustering and the tectonic regime respectively.

  7. Resonance broadening and van der waals broadening

    NASA Astrophysics Data System (ADS)

    Mashonkina, L.

    2010-11-01

    Resonance broadening is important for the hydrogen lines in the spectra of F-type and later stars. In the corresponding temperature regime, the extended wings of the Balmer lines are used as a stellar effective temperature indicator. We show the effect of the use of two broadening theories, Ali & Griem (1965, 1966) and Barklem et al. (2000a, 2000b), on the effective temperature derived in non-LTE from Hα and Hβ in the Sun and the metal-poor star HD19445. Van der Waals broadening is important for strong spectral lines in the atmospheres of F-type and later stars. For the selected transitions in Ca I and Ca II, line profile comparisons are made between applying the van der Waals damping constants from laboratory measurements, the ABO perturbation theory, and the classic Unsöld approximation.

  8. van der Waals Forces between Cylinders

    PubMed Central

    Mitchell, D. J.; Ninham, B. W.; Richmond, P.

    1973-01-01

    We derive the retarded van der Waals interaction between two long thin parallel dielectric cylinders immersed in a solvent. The result shows that the ultraviolet interactions which may be responsible for the specificity of macromolecular interactions do not operate strongly over distances R ≥ 50 Å. For greater distances the contribution of these frequencies ξ is damped by a factor ∞ e-ξR/c. PMID:4696763

  9. A further patient with van Maldergem syndrome.

    PubMed

    Neuhann, T M; Müller, D; Hackmann, K; Holzinger, S; Schrock, E; Di Donato, N

    2012-06-01

    We report on a male patient with the proposed diagnosis of the rare but very distinct entity of van Maldergem syndrome. His parents are first cousins. At the age of 4 years the boy presented with severe developmental delay, talipes equinovarus, finger camptodactyly with interphalangeal pterygium, joint laxity, bilateral microtia, and a dysmorphic facies. He showed bilateral epicanthus, telecanthus, short palpebral fissures, broad flat nasal bridge, and dental malocclusion. The combination of the specific facial features with camptodactyly, interphalangeal pterygium, joint laxity and developmental delay led to the diagnosis of van Maldergem syndrome. The medical history was further on significant for pharyngeal instability requiring the placement of a tracheostomy tube, an inguinal hernia, hip subluxation, small kidneys and genital abnormalities (micropenis, bifid scrotum, cryptorchidism). Due to severe feeding difficulties permanent tube feeding was required. Metabolic tests (newborn metabolic screening, 7-dehydrocholesterol, amino acids, organic acids in urine) and chromosomal analysis (450-500 bands; 46,XY) were normal. Molecular karyotyping revealed two parental CNVs (paternal deletion of 9q33.1; maternal duplication of 11p15.1), which are unlikely to contribute to the patient's phenotype. Taken together, the report on a further patient with van Maldergem syndrome expands the clinical spectrum of the condition by adding genital malformations, hernia, pharyngeal instability, and subluxation of the hip. PMID:22469822

  10. Xanthopsia and van Gogh's yellow palette.

    PubMed

    Arnold, W N; Loftus, L S

    1991-01-01

    A survey of van Gogh's work from 1886 to 1890 indicated that paintings with a yellow dominance were numerous, episodic, and multi-regional. His underlying illness, by his own admission, affected his life and work; furthermore, episodes of malnutrition, substance abuse, environmental exposure, and drug experimentation (all evident from correspondence) exacerbated his condition. Accordingly, we reviewed plausible agents that might have modified the artist's colour perception. Xanthopsia due to overdosage of digitalis or santonin is well documented elsewhere, but evidence of useage of either drug by van Gogh cannot be substantiated. It is unlikely that ageing of the human lens was an influence because of the artist's youth. Sunstroke is too restrictive to fit the multiplicity of regions and motifs. Hallucinations induced by absinthe, the popular liqueur of the period, may explain particular canvases but not the majority of 'high yellow' paintings. Van Gogh's proclivity for exaggerated colours and his embrance of yellow in particular are clear from his letters and, in contradistinction to chemical or physical insults modifying perception, artistic preference is the best working hypothesis to explain the yellow dominance in his palette. PMID:1794418

  11. Grizzly bear denning and potential conflict areas in the Greater Yellowstone Ecosystem

    USGS Publications Warehouse

    Podruzny, Shannon; Cherry, Steve; Schwartz, Charles C.; Landenburger, Lisa

    2002-01-01

    Increasing winter use of steep, high-elevation terrain by backcountry recreationists has elevated concern about disturbance of denning grizzly bears (Ursus arctos) in the Greater Yellowstone Ecosystem (GYE). To help identify areas where such conflicts might occur, we developed a spatially explicit model to predict potential denning areas in the GYE. Using a scan area of 630 m around each location, we assigned site attributes to 344 den locations of radio-trackedg rizzly bears from 1975-99. Attributesi dentified as predictorsf or the analysis included elevation, slope, an index of solar radiation, and forest cover. We used the Mahalanobis distance statistic to model the similarity between sites used by denning bears and each cell in the data layers. We used the final Mahalanobis distance model to produce maps of the study area. Potential denning habitat, based upon the model, is abundantw ithin the GYE. Ourr esultsc an be used by land managementa gencies to identifyp otentialc onflict sites and minimize effects of regulated activities on denning grizzly bears. We illustrate how the Gallatin National Forest (GNF) used the model to examine the overlap between potential snowmobile use areas and potential denning habitat as part of a Biological Assessment submitted to the U.S. Fish and Wildlife Service.

  12. Management of dens in dente associated with a chronic periapical lesion.

    PubMed

    Mehta, Vivek; Raheja, Anupama; Singh, Rajeev Kumar

    2015-01-01

    Dens in dente is characterised as a developmental anomaly resulting from invagination of the enamel organ into the dental papilla. It is a rare malformation of teeth, showing a wide spectrum of morphological variations such as gemination, microdontia, taurodontism, dentinogenesis imperfecta, supernumerary tooth and hyperplasias, resulting frequently in early pulp necrosis. Maxillary lateral incisors are the commonest teeth to be affected by dental malformations-supernumerary tooth, talon cusp, congenitally missing tooth and dens in dente. We describe the management of a case of dens in dente in a maxillary lateral incisor with a periradicular lesion. PMID:26655667

  13. Den Entry Behavior in Scandinavian Brown Bears: Implications for Preventing Human Injuries

    PubMed Central

    Sahlén, Veronica; Friebe, Andrea; Sæbø, Solve; Swenson, Jon E; Støen, Ole-Gunnar

    2015-01-01

    Encounters between Scandinavian brown bears (Ursus arctos) and humans that result in human injuries and fatalities typically coincide with den entry in October and November, and commonly occur near a den. Our aim was to determine when bears arrive at their dens, identify potential predictors of this event, document behavior and activity associated with this period, and attempt to explain the increased risk of bear-caused human injuries in this period. We analyzed global positioning system (GPS) location and activity data from brown bears in south-central Sweden, using generalized linear mixed models, statistical process control, and activity analyses. Bears arrived at their den sites between 6 October and 1 December. Timing varied by reproductive category, bear age, and year. Half of all bears significantly reduced their activity before arriving at the den area: on average 2,169 m away from the den and 1.8 days before arrival. The other half reduced their activity after arriving at the den area. The latter bears took longer time to reach hibernation activity levels, but we did not find a difference in the start date of hibernation between the 2 groups. Bears also appeared to be sensitive to disturbance in this period, with higher den abandonment rates than later in winter, particularly for males and for bears that had not visited their den sites previously. Den entry occurred from October to December, with high variability and poor predictability of its timing. Therefore, restricting hunting or other recreation activities to reduce risk of injury by bears and disturbing bears probably would be both impractical and ineffective. Our findings can be used to educate hunters about bear behavior at this time of year. Many people associate dens with an increased risk of a bear responding aggressively to disturbance to defend its den, but our results indicate that other behavioral, and possibly physiological, changes in this period also may be involved. © 2014 The

  14. Conventional Treatment of Maxillary Incisor Type III Dens Invaginatus with Periapical Lesion: A Case Report

    PubMed Central

    Borges, Álvaro Henrique; Semenoff Segundo, Alex; Nadalin, Michele Regina; Pedro, Fábio Luís Miranda; da Cruz Filho, Antônio Miranda; Sousa-Neto, Manoel Damião

    2011-01-01

    Dens invaginatus is a developmental dental anomaly clinically characterized by a palatine furrow that can be limited to the coronal pulp or may extend to the radicular apex. The purpose of this paper was to present a clinical case of type III dens invaginatus, identified on the maxillary right central incisor in anterior periapical radiographs, in which the tooth was submitted to conventional endodontic treatment. The results obtained after five years of clinical and radiographic followup demonstrated that conventional endodontic treatment is a clinically viable alternative in cases of type III dens invaginatus. PMID:21991460

  15. A unique Austin Chalk reservoir, Van field, Van Zandt County, Texas

    SciTech Connect

    Lowe, J.T. )

    1990-09-01

    Significant shallow oil production from the Austin Chalk was established in the Van field, Van Zandt County, in East Texas in the late 1980s. The Van field structure is a complexly faulted domal anticline created by salt intrusion. The Woodbine sands, which underlie the Austin Chalk, have been and continue to be the predominant reservoir rocks in the field. Evidence indicates that faults provided vertical conduits for migration of Woodbine oil into the Austin Chalk where it was trapped along the structural crest. The most prolific Austin Chalk production is on the upthrown side of the main field fault, as is the Woodbine. The Austin Chalk is a soft, white to light gray limestone composed mostly of coccoliths with some pelecypods. Unlike the Austin Chalk in the Giddings and Pearsall fields, the chalk at Van was not as deeply buried and therefore did not become brittle and susceptible to tensional or cryptic fracturing. The shallow burial in the Van field was also important in that it allowed the chalk to retain primary microporosity. The production comes entirely from this primary porosity. In addition to the structural position and underlying oil source from the Woodbine, the depositional environment and associated lithofacies are also keys to the reservoir quality in the Van field as demonstrated by cores from the upthrown and downthrown (less productive) sides of the main field fault. It appears that at the time of Austin Chalk deposition, the main field fault was active and caused the upthrown side to be a structural high and a more agreeable environment for benthonic organisms such as pelecypods and worms. The resulting bioturbation enhanced the reservoir's permeability enough to allow migration and entrapment of the oil. Future success in exploration for analogous Austin Chalk reservoirs will require the combination of a favorable environment of deposition, a nearby Woodbine oil source, and a faulted trap that will provide the conduit for migration.

  16. [Immediate implant loading using DenTi implants--our long-term experience. Part 2: Experience with DenTi implants as reflected in the literature].

    PubMed

    István, Vajdovich; Mihály, Bandula; Péter, Bóka; Zsuzsanna, Tóth

    2006-12-01

    Immediate loading of dental implants have been widely used to retain and support cross-arch partial dentures. 3-6 months after implantation the osseointegration is established. This period may be shortened with immediate loading of implants. The purpose of this study was to compare the long term experience of immediate loading of DenTi implants and the results reported in available literature. The most relevant articles were selected from current available literature. The influencing factors of success of immediate loading (surgery,- host,- implant and occlusion-related factors) were investigated and discussed in this article. The result of the evaluation showed that the success rate of the immediate loaded DenTi implants with large grit sandblasted treatment and acid etched surface was higher than 95 %. The success rate of the immediate loaded DenTi implants is similar to the ones reported in the available literature. PMID:17444128

  17. A new Lagerstätte from the Middle Ordovician St. Peter Formation in northeast Iowa, USA

    NASA Astrophysics Data System (ADS)

    Liu, Huaibao P.; McKay, Robert M.; Young, Jean N.; Witzke, Brian J.; McVey, Kathlyn J.; Liu, Xiuying

    2006-11-01

    A new fossil fauna has been discovered from a recently recognized shale unit within the middle Ordovician St. Peter Formation in northeast Iowa. It contains a variety of invertebrates and vertebrates, including soft body tissues, impressions, and 3-dimensionalpreservations. The exceptional preservation reveals a new Konservat-Lagerstätte, the Winneshiek Lagerstätte, and opens a unique window into the community that inhabited the margins of the Laurentian cratonic seaway during Middle Ordovician transgression. Among the fossils, several conodont assemblages, including the apparatus of enigmatic coleodontids, are preserved. Some conodont assemblages associated with soft body tissues are particularly noteworthy.

  18. A new Lagerstätte from the Middle Ordovician St. Peter formation in northeast Iowa, USA

    USGS Publications Warehouse

    Liu, Huaibao P.; McKay, Robert M.; Young, Jean N.; Witzke, Brian J.; McVey, Kathlyn J.; Liu, Xiuying

    2006-01-01

    A new fossil fauna has been discovered from a recently recognized shale unit within the middle Ordovician St. Peter Formation in northeast Iowa. It contains a variety of invertebrates and vertebrates, including soft body tissues, impressions, and 3-dimensionalpreservations. The exceptional preservation reveals a new Konservat-Lagerstätte, the Winneshiek Lagerstätte, and opens a unique window into the community that inhabited the margins of the Laurentian cratonic seaway during Middle Ordovician transgression. Among the fossils, several conodont assemblages, including the apparatus of enigmatic coleodontids, are preserved. Some conodont assemblages associated with soft body tissues are particularly noteworthy.

  19. Sex steroid and prolactin profiles in male American black bears (Ursus americanus) during denning.

    PubMed

    Tsubota, T; Garshelis, D L; Nelson, R A; Bahr, J M

    1999-01-01

    Serum sex steroid and prolactin profiles were examined in the male American black bear, Ursus americanus during denning. Sera collected in December and the following March from 8 denning male black bears in Minnesota, U.S.A. were assayed for testosterone, estradiol-17 beta and prolactin. Eight bears were confirmed to be the denning mode based on a serum urea to creatinine ratio less than 10. Serum testosterone concentrations tended to increase from December to the subsequent March whereas serum estradiol-17 beta concentrations tended to decrease during this period. There were few changes in serum prolactin concentrations between December and March. These findings suggest that spermatogenesis and testicular steroidogenesis initiated during denning may be influenced by changes in serum sex steroid concentrations in the American black bear. PMID:10027172

  20. Van Kampen modes for bunch longitudinal motion

    SciTech Connect

    Burov, A.; /Fermilab

    2010-09-01

    Conditions for existence, uniqueness and stability of bunch steady states are considered. For the existence uniqueness problem, simple algebraic equations are derived, showing the result both for the action and Hamiltonian domain distributions. For the stability problem, van Kampen theory is used. Emerging of discrete van Kampen modes show either loss of Landau damping, or instability. This method can be applied for an arbitrary impedance, RF shape and beam distribution function Available areas on intensity-emittance plane are shown for resistive wall wake and single harmonic, bunch shortening and bunch lengthening RF configurations. Language of van Kampen modes is a powerful tool for studying beam stability. Its unique efficiency reveals itself in those complicated cases, when the dielectric function cannot be obtained, as it is for the longitudinal bunch motion. Emergence of a discrete mode means either loss of Landau damping or instability. By definition, the discrete modes lie outside the continuous incoherent spectrum, but they still may stay within the bucket. In the last case, the discrete mode would disappear after a tiny portion of resonant particles would be added. However, if the discrete mode lie outside the bucket, the Landau damping cannot be restored by tiny perturbation of the particle distribution; LLD is called radical in that case. For a given bunch emittance and RF voltage, the intensity is limited either by reduction of the bucket acceptance or by (radical) LLD. In this paper, results are presented for longitudinal bunch stability in weak head-tail approximation and resistive wall impedance; three RF configurations are studied: single harmonic, bunch shortening and bunch lengthening. It is shown that every RF configuration may be preferable, depending on the bunch emittance and intensity.

  1. van der Waals Heterostructures Grown by MBE

    NASA Astrophysics Data System (ADS)

    Hinkle, Christopher

    In this work, we demonstrate the high-quality MBE heterostructure growth of various layered 2D materials by van der Waals epitaxy (VDWE). The coupling of different types of van der Waals materials including transition metal dichalcogenide thin films (e.g., WSe2, WTe2, HfSe2) , insulating hexagonal boron nitride (h-BN), and topological insulators (e.g., Bi2Se3) allows for the fabrication of novel electronic devices that take advantage of unique quantum confinement and spin-based characteristics. The relaxed lattice-matching criteria of van der Waals epitaxy has allowed for high-quality heterostructure growth with atomically abrupt interfaces, allowing us to couple these materials based primarily on their band alignment and electronic properties. We will discuss the impact of sample preparation, surface reactivity, and lattice mismatch of various substrates (sapphire, graphene, TMDs, Bi2Se3) on the growth mode and quality of the films and will discuss our studies of substrate temperature and flux rates on the resultant growth and grain size. Structural and chemical characterization was conducted via reflection high energy electron diffraction (RHEED, X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning tunneling microscopy/spectroscopy (STM/S), atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS), and Raman spectroscopy. Experimentally determined band alignments have been determined and compared with first-principles calculations allowing the design of novel low-power logic and magnetic memory devices. Initial results from the electrical characterization of these grown thin films and some simple devices will also be presented. These VDWE grown layered 2D materials show significant potential for fabricating novel heterostructures with tunable band alignments and magnetic properties for a variety of nanoelectronic and optoelectronic applications.

  2. [Johann van Beethoven (1776-1848)].

    PubMed

    Eikermann, Erika

    2012-01-01

    The article about the life and achievements of the apothecary Johann van Beethoven, the younger brother of the composer Ludwig van Beethoven, depicts a vivid picture of life in the 18th, 19t century. Research on archived original documents in Bonn, Vienna and Linz on the Danube made it possible to reveal details about the relationship inside this famous family and describes the hurdles of life of a successful apothecary. In 1776 Johann van Beethoven was born as the fourth child of the Beethoven family, a family of Bonner musicians. In 1790 he began his apprenticeship to become an apothecary at the Bonner "Hofapotheke". Towards the end of 1795 he moved to join his older brothers Ludwig and Karl in Vienna. During his time there he worked as a "subject" in various Viennese pharmacies. However in 1808 he purchased the pharmacy "Zur Goldenen Krone" in Linz on the Danube. His new pharmacy flourished, supplying first the Napoleonic occupation troops, and later the Austrian Military with medicines and field dressing/bandage materials. When in 1812 he married his Housekeeper, his Brother Ludwig opposed harshly, on reasons of social status and on moral grounds. Four years later, in 1816 Johann sold the pharmacy in Linz and founded a new pharmacy in Urfahr, on the opposite bank of the Danube. In 1819 he became a squire (or landowner), when he purchased a manor estate in Gneixendorf, near Krems on the Danube. In spite of his numerous duties as an apothecary and squire, Johann was frequently resident in Vienna, supporting his brother both emotionally and pharmaceutically. At the end of his life Johann sold both his pharmacy and the Gneixendorf estate, and spent his last years as a private gentleman living a dazzling lifestyle in Vienna. He died on January 12th 1848 and was buried in Vienna's "Waldmüllerpark". PMID:23527448

  3. Nonsurgical endodontic management of dens invaginatus with open apex: A case report

    PubMed Central

    Rani, Nidhi; Sroa, Renu B

    2015-01-01

    Dens invaginatus is a rare malformation with a widely varied morphology. It typically affects permanent maxillary lateral incisors, central incisors, and premolars. This article demonstrates rapid management of type II dens invagination with open apex and large periradicular lesion using calcium hydroxide as intracanal medicament for 1-week followed by apical plug formation with mineral trioxide aggregate Plus and lateral condensation of Gutta-percha. At 24-month follow-up, the patient was asymptomatic and lesion was entirely resolved. PMID:26751206

  4. The microscopes of Antoni van Leeuwenhoek.

    PubMed

    van Zuylen, J

    1981-03-01

    The seventeenth-century Dutch microscopist, Antoni van Leeuwenhoek, was the first man to make a protracted study of microscopical objects, and, unlike his contemporary Robert Hooke, he viewed by transmitted light. Leeuwenhoek made over 500 of his own, curious, simple microscopes, but now only nine are known to exist. The exact nature of the lenses Leeuwenhoek made, has for long been a puzzle. The existing microscopes have now been examined in detail, and their optical characteristics measured and tabulated. It is proposed that the lens of highest magnification, x 266, was made using a special blown bubble technique. PMID:7012367

  5. ITT Continental Baking tests electric vans

    SciTech Connect

    Not Available

    1983-02-01

    ITT Continental Baking Co., operator of one of the largest truck fleets in the U.S., is studying battery power as an alternative fuel for the future. The company currently has a total of 10 lead battery-powered vans delivering bread and cake products in Sacramento, California, and Spokane, Washington. Through a cost-sharing program with the U.S. Department of Energy (DOE), the company will operate the vehicles through at least June 30, 1985, gathering data on their performance. The joint program began in 1981.

  6. Bernard van Leer Foundation Annual Review 1993 = Fundacion Bernard van Leer Revista Anual 1993.

    ERIC Educational Resources Information Center

    Bernard Van Leer Foundation, The Hague (Netherlands).

    This report, in both English and Spanish versions, aims to highlight the Bernard van Leer Foundation's identity, objectives, and major activities, as well as the work undertaken by the projects the foundation supports. The review features articles on the Foundation's work on advocacy, supporting families living in disadvantaged circumstances,…

  7. Fundacion Bernard van Leer, Boletin Informativo, 1987-1996 (Bernard van Leer Foundation Information Bulletin).

    ERIC Educational Resources Information Center

    Fundacion Bernard van Leer, Boletin Informativo, 1996

    1996-01-01

    This document consists of ten annual Spanish Language Bulletins, published during the period 1987-1996. The early bulletins were largely composed of selections originally published in the Bernard van Lear Foundation's English-Language "Newsletter The articles discuss topics such as: (1) parents as children's first teachers; (2) health and…

  8. Cell cycle progression in denV-transfected murine fibroblasts exposed to ultraviolet radiation.

    PubMed

    Kusewitt, D F; Budge, C L; Nolla, H A; Edwards, B S; Ley, R D

    1992-09-01

    Repair-proficient murine fibroblasts transfected with the denV gene of bacteriophage T4 repaired 70-80% of pyrimidine dimers within 24 h after exposure to 150 J/m2 ultraviolet radiation (UVR) from an FS-40 sunlamp. Under the same conditions, control cells repaired only about 20% of UVR-induced pyrimidine dimers. After UVR exposure, both control and denV-transfected cells exhibited some degree of DNA-synthesis inhibition, as determined by flow cytometric analysis of cell-cycle kinetics in propidium iodide-stained cells. DenV-transfected cells had a longer and more profound S phase arrest than control cells, but both control and denV-transfected cells had largely recovered from UVR effects on cell-cycle kinetics by 48 h after UVR exposure. Inhibition of DNA synthesis by UVR was also measured by determining post-UVR incorporation of bromodeoxyuridine (BrdU). The amount of BrdU incorporated was quantitated by determining with flow cytometry the quenching of Hoechst dye 33342 by BrdU incorporated in cellular DNA. DenV-transfected cells showed more marked inhibition of BrdU incorporation after low fluences of UVR than control cells. Differences between denV-transfected and control cells in cell-cycle kinetics following UVR exposure may be related to differences in mechanisms of repair when excision repair of pyrimidine dimers is initiated by endonuclease V instead of cellular repair enzymes. PMID:1380650

  9. Remote identification of maternal polar bear (Ursus maritimus) denning habitat on the Colville River Delta, Alaska

    NASA Astrophysics Data System (ADS)

    Blank, Justin J.

    High resolution digital aerial photographs (1 foot pixel size) of the Colville River Delta, Alaska were examined in 3D, with the use of a digital photogrammetric workstation. Topographic features meeting the criteria required for adequate snow accumulation, and subsequent construction of terrestrial polar bear maternal dens, were identified and digitized into an ArcGIS line shapefile. Effectiveness, efficiency, and accuracy were improved when compared to previous polar bear denning habitat efforts which utilized contact photo prints and a pocket stereoscope in other geographic areas of northern Alaska. Accuracy of photograph interpretation was systematically evaluated visually from the air with the use of a helicopter and physically on the ground. Results show that the mapping efforts were successful in identifying den habitat 91.3% of the time. Knowledge denning habitat can improve and inform decision making by managers and regulators when considering travel and development in the study area. An understanding of polar bear denning habitat extent and location will be a crucial tool for planning activities within the study area in a way that minimizes conflicts with maternal dens.

  10. Arctic foxes as ecosystem engineers: increased soil nutrients lead to increased plant productivity on fox dens

    PubMed Central

    Gharajehdaghipour, Tazarve; Roth, James D.; Fafard, Paul M.; Markham, John H.

    2016-01-01

    Top predators can provide fundamental ecosystem services such as nutrient cycling, and their impact can be even greater in environments with low nutrients and productivity, such as Arctic tundra. We estimated the effects of Arctic fox (Vulpes lagopus) denning on soil nutrient dynamics and vegetation production near Churchill, Manitoba in June and August 2014. Soils from fox dens contained higher nutrient levels in June (71% more inorganic nitrogen, 1195% more extractable phosphorous) and in August (242% more inorganic nitrogen, 191% more extractable phosphorous) than adjacent control sites. Inorganic nitrogen levels decreased from June to August on both dens and controls, whereas extractable phosphorous increased. Pup production the previous year, which should enhance nutrient deposition (from urine, feces, and decomposing prey), did not affect soil nutrient concentrations, suggesting the impact of Arctic foxes persists >1 year. Dens supported 2.8 times greater vegetation biomass in August, but δ15N values in sea lyme grass (Leymus mollis) were unaffected by denning. By concentrating nutrients on dens Arctic foxes enhance nutrient cycling as an ecosystem service and thus engineer Arctic ecosystems on local scales. The enhanced productivity in patches on the landscape could subsequently affect plant diversity and the dispersion of herbivores on the tundra. PMID:27045973

  11. Arctic foxes as ecosystem engineers: increased soil nutrients lead to increased plant productivity on fox dens.

    PubMed

    Gharajehdaghipour, Tazarve; Roth, James D; Fafard, Paul M; Markham, John H

    2016-01-01

    Top predators can provide fundamental ecosystem services such as nutrient cycling, and their impact can be even greater in environments with low nutrients and productivity, such as Arctic tundra. We estimated the effects of Arctic fox (Vulpes lagopus) denning on soil nutrient dynamics and vegetation production near Churchill, Manitoba in June and August 2014. Soils from fox dens contained higher nutrient levels in June (71% more inorganic nitrogen, 1195% more extractable phosphorous) and in August (242% more inorganic nitrogen, 191% more extractable phosphorous) than adjacent control sites. Inorganic nitrogen levels decreased from June to August on both dens and controls, whereas extractable phosphorous increased. Pup production the previous year, which should enhance nutrient deposition (from urine, feces, and decomposing prey), did not affect soil nutrient concentrations, suggesting the impact of Arctic foxes persists >1 year. Dens supported 2.8 times greater vegetation biomass in August, but δ(15)N values in sea lyme grass (Leymus mollis) were unaffected by denning. By concentrating nutrients on dens Arctic foxes enhance nutrient cycling as an ecosystem service and thus engineer Arctic ecosystems on local scales. The enhanced productivity in patches on the landscape could subsequently affect plant diversity and the dispersion of herbivores on the tundra. PMID:27045973

  12. A Rare Case of Crowned Dens Syndrome Mimicking Aseptic Meningitis

    PubMed Central

    Takahashi, Teruyuki; Minakata, Yugo; Tamura, Masato; Takasu, Toshiaki; Murakami, Marohito

    2013-01-01

    Background Crowned dens syndrome (CDS), related to microcrystalline deposition in the periodontoid process, is the main cause of acute or chronic cervical pain. Microcrystal-line deposition most often consists of calcium pyrophosphate dehydrate crystals and/or hydroxyapatite crystals. Case Presentation This report describes the case of an 89-year-old woman who presented with sudden onset, high fever, severe occipital headache, and neck stiffness. A laboratory examination revealed a markedly elevated white blood cell count (11,100/µl) and C-reactive protein level (23.8 mg/dl). These clinical findings suggested severe infection such as meningitis with sepsis. However, the results of blood culture, serum endotoxin, and procalcitonin were all negative, and cerebrospinal fluid studies revealed only a slight abnormality. The patient was first diagnosed with meningitis and treated with antiviral and antibiotic agents as well as non-steroidal anti-inflammatory drugs, but they only had limited effects. A cervical plain computed tomography (CT) scan and its three-dimensional (3D) reconstruction detected a remarkable crown-like calcification surrounding the odontoid process. On the basis of the CT findings, the patient was diagnosed as a severe case of CDS and was immediately treated with corticosteroids. The patient's condition drastically improved within a week after one course of corticosteroid therapy. Conclusion Some atypical symptoms of CDS are misleading and may be misdiagnosed as meningitis, as happened in our case. A CT scan, especially a 3D-CT scan, is necessary and useful for a definitive diagnosis of CDS. CDS should be considered as a differential diagnosis of a possible etiology for fever, headache, and cervical pain of unknown origin. PMID:23569451

  13. An Efficient Image Encryption Scheme Based on a Peter De Jong Chaotic Map and a RC4 Stream Cipher

    NASA Astrophysics Data System (ADS)

    Hanchinamani, Gururaj; Kulkarni, Linganagouda

    2015-09-01

    Security is a vital issue in communication and storage of the images and encryption is one of the ways to ensure the security. This paper proposes an efficient image encryption scheme based on a Peter De Jong chaotic map and a RC4 stream cipher. A Peter De Jong map is employed to determine the initial keys for the RC4 stream generator and also during permutation stage. The RC4 stream generator is utilized to generate the pseudo random numbers for the pixel value rotation and diffusion operations. Each encryption round is comprised of three stages: permutation, pixel value rotation and diffusion. The permutation is based on scrambling the rows and columns, in addition, circular rotations of the rows and columns in alternate orientations. The second stage circularly rotates each and every pixel value by utilizing M × N pseudo random numbers. The last stage carries out the diffusion twice by scanning the image in two different ways. Each of the two diffusions accomplishes the diffusion in two orientations (forward and backward) with two previously diffused pixels and two pseudo random numbers. The security and performance of the proposed method is assessed thoroughly by using key space, statistical, differential, entropy and performance analysis. Moreover, two rounds of the call to the encrypt function provide the sufficient security. The experimental results show that the proposed encryption scheme is computationally fast with high security.

  14. vanC cluster of vancomycin-resistant Enterococcus gallinarum BM4174.

    PubMed

    Arias, C A; Courvalin, P; Reynolds, P E

    2000-06-01

    Glycopeptide-resistant enterococci of the VanC type synthesize UDP-muramyl-pentapeptide[D-Ser] for cell wall assembly and prevent synthesis of peptidoglycan precursors ending in D-Ala. The vanC cluster of Enterococcus gallinarum BM4174 consists of five genes: vanC-1, vanXY(C), vanT, vanR(C), and vanS(C). Three genes are sufficient for resistance: vanC-1 encodes a ligase that synthesizes the dipeptide D-Ala-D-Ser for addition to UDP-MurNAc-tripeptide, vanXY(C) encodes a D,D-dipeptidase-carboxypeptidase that hydrolyzes D-Ala-D-Ala and removes D-Ala from UDP-MurNAc-pentapeptide[D-Ala], and vanT encodes a membrane-bound serine racemase that provides D-Ser for the synthetic pathway. The three genes are clustered: the start codons of vanXY(C) and vanT overlap the termination codons of vanC-1 and vanXY(C), respectively. Two genes which encode proteins with homology to the VanS-VanR two-component regulatory system were present downstream from the resistance genes. The predicted amino acid sequence of VanR(C) exhibited 50% identity to VanR and 33% identity to VanR(B). VanS(C) had 40% identity to VanS over a region of 308 amino acids and 24% identity to VanS(B) over a region of 285 amino acids. All residues with important functions in response regulators and histidine kinases were conserved in VanR(C) and VanS(C), respectively. Induction experiments based on the determination of D,D-carboxypeptidase activity in cytoplasmic extracts confirmed that the genes were expressed constitutively. Using a promoter-probing vector, regions upstream from the resistance and regulatory genes were identified that have promoter activity. PMID:10817725

  15. Despotism and Risk of Infanticide Influence Grizzly Bear Den-Site Selection

    PubMed Central

    Libal, Nathan S.; Belant, Jerrold L.; Leopold, Bruce D.; Wang, Guiming; Owen, Patricia A.

    2011-01-01

    Given documented social dominance and intraspecific predation in bear populations, the ideal despotic distribution model and sex hypothesis of sexual segregation predict adult female grizzly bears (Ursus arctos) will avoid areas occupied by adult males to reduce risk of infanticide. Under ideal despotic distribution, juveniles should similarly avoid adult males to reduce predation risk. Den-site selection and use is an important component of grizzly bear ecology and may be influenced by multiple factors, including risk from conspecifics. To test the role of predation risk and the sex hypothesis of sexual segregation, we compared adult female (n = 142), adult male (n = 36), and juvenile (n = 35) den locations in Denali National Park and Preserve, Alaska, USA. We measured elevation, aspect, slope, and dominant land cover for each den site, and used maximum entropy modeling to determine which variables best predicted den sites. We identified the global model as the best-fitting model for adult female (area under curve (AUC) = 0.926) and elevation as the best predictive variable for adult male (AUC = 0.880) den sites. The model containing land cover and elevation best-predicted juvenile (AUC = 0.841) den sites. Adult females spatially segregated from adult males, with dens characterized by higher elevations ( = 1,412 m, SE = 52) and steeper slopes ( = 21.9°, SE = 1.1) than adult male (elevation:  = 1,209 m, SE = 76; slope:  = 15.6°, SE = 1.9) den sites. Juveniles used a broad range of landscape attributes but did not avoid adult male denning areas. Observed spatial segregation by adult females supports the sex hypothesis of sexual segregation and we suggest is a mechanism to reduce risk of infanticide. Den site selection of adult males is likely related to distribution of food resources during spring. PMID:21935378

  16. Despotism and risk of infanticide influence grizzly bear den-site selection.

    PubMed

    Libal, Nathan S; Belant, Jerrold L; Leopold, Bruce D; Wang, Guiming; Owen, Patricia A

    2011-01-01

    Given documented social dominance and intraspecific predation in bear populations, the ideal despotic distribution model and sex hypothesis of sexual segregation predict adult female grizzly bears (Ursus arctos) will avoid areas occupied by adult males to reduce risk of infanticide. Under ideal despotic distribution, juveniles should similarly avoid adult males to reduce predation risk. Den-site selection and use is an important component of grizzly bear ecology and may be influenced by multiple factors, including risk from conspecifics. To test the role of predation risk and the sex hypothesis of sexual segregation, we compared adult female (n = 142), adult male (n = 36), and juvenile (n = 35) den locations in Denali National Park and Preserve, Alaska, USA. We measured elevation, aspect, slope, and dominant land cover for each den site, and used maximum entropy modeling to determine which variables best predicted den sites. We identified the global model as the best-fitting model for adult female (area under curve (AUC) = 0.926) and elevation as the best predictive variable for adult male (AUC = 0.880) den sites. The model containing land cover and elevation best-predicted juvenile (AUC = 0.841) den sites. Adult females spatially segregated from adult males, with dens characterized by higher elevations (mean= 1,412 m, SE = 52) and steeper slopes (mean = 21.9°, SE = 1.1) than adult male (elevation: mean = 1,209 m, SE = 76; slope: mean = 15.6°, SE = 1.9) den sites. Juveniles used a broad range of landscape attributes but did not avoid adult male denning areas. Observed spatial segregation by adult females supports the sex hypothesis of sexual segregation and we suggest is a mechanism to reduce risk of infanticide. Den site selection of adult males is likely related to distribution of food resources during spring. PMID:21935378

  17. Astronaut James van Hoften working with Syncom IV-3 satellite

    NASA Technical Reports Server (NTRS)

    1985-01-01

    A 16mm motion picture camera was used to show Astronaut James D. van Hoften as he gives a shove to the previously troubled Syncom IV-3 communications satellite. Dr. van Hoften stands on a foot restraint/extension to the remote manipulator system (RMS) arm.

  18. United Parcel Service Evaluates Hybrid Electric Delivery Vans (Fact Sheet)

    SciTech Connect

    Not Available

    2010-02-01

    This fact sheet describes how the National Renewable Energy Laboratory's Fleet Test and Evaluation team evaluated the 12-month, in-service performance of six Class 4 hybrid electric delivery vans - fueled by regular diesel - and six comparable conventional diesel vans operated by the United Parcel Service.

  19. Characterizing the van Hiele Levels of Development in Geometry.

    ERIC Educational Resources Information Center

    Burger, William F.; Shaughnessy, J. Michael

    1986-01-01

    Describes the van Hiele levels of reasoning in geometry according to responses to clinical interview tasks concerning triangles and quadrilaterals. Subjects were 13 students from grades 1 through 12 plus a university mathematics major. Students' behavior on tasks was consistent with the van Hiele original general description of the levels.…

  20. 53. Photographer unknown Date unknown VAN DUZEN BRIDGE, HUMBOLDT COUNTY, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    53. Photographer unknown Date unknown VAN DUZEN BRIDGE, HUMBOLDT COUNTY, SECTION F, HIGHWAY 1. 1. 1-HUM-1-F #24, VAN DUZEN BR. APPRAOCH/ST. 167+50. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  1. Heading for the hills: risk avoidance drives den site selection in African wild dogs.

    PubMed

    Jackson, Craig R; Power, R John; Groom, Rosemary J; Masenga, Emmanuel H; Mjingo, Ernest E; Fyumagwa, Robert D; Røskaft, Eivin; Davies-Mostert, Harriet

    2014-01-01

    Compared to their main competitors, African wild dogs (Lycaon pictus) have inferior competitive abilities and interspecific competition is a serious fitness-limiting factor. Lions (Panthera leo) are the dominant large carnivore in African savannah ecosystems and wild dogs avoid them both spatially and temporally. Wild dog young are particularly vulnerable and suffer high rates of mortality from lions. Since lions do not utilize all parts of the landscape with an equal intensity, spatial variation in lion densities can be exploited by wild dogs both during their general ranging behaviour, but more specifically when they are confined to a den with vulnerable young. Since patches of rugged terrain are associated with lower lion densities, we hypothesized that these comparatively safe habitats should be selected by wild dogs for denning. We investigated the relationship between the distribution of 100 wild dog den sites and the occurrence of rugged terrain in four wild dog populations located in Tanzania, Zimbabwe and South Africa. A terrain ruggedness index was derived from a 90 m digital elevation model and used to map terrain ruggedness at each site. We compared characteristics of actual and potential (random) den sites to determine how wild dogs select den sites. The distributions of wild dog dens were strongly associated with rugged terrain and wild dogs actively selected terrain that was more rugged than that available on average. The likelihood of encountering lions is reduced in these habitats, minimizing the risk to both adults and pups. Our findings have important implications for the conservation management of the species, especially when assessing habitat suitability for potential reintroductions. The simple technique used to assess terrain ruggedness may be useful to investigate habitat suitability, and even predict highly suitable denning areas, across large landscapes. PMID:24918935

  2. Dancing bunches as Van Kampen modes

    SciTech Connect

    Burov, A.; /Fermilab

    2011-03-01

    Van Kampen modes are eigen-modes of Jeans-Vlasov equation [1-3]. Their spectrum consists of continuous and, possibly, discrete parts. Onset of a discrete van Kampen mode means emergence of a coherent mode without any Landau damping; thus, even a tiny couple-bunch wake is sufficient to drive instability. Longitudinal instabilities observed at Tevatron [4], RHIC [5] and SPS [6] can be explained as loss of Landau damping (LLD), which is shown here to happen at fairly low impedances. For repulsive wakes and single-harmonic RF, LLD is found to be extremely sensitive to steepness of the bunch distribution function at small amplitudes. Based on that, a method of beam stabilization is suggested. Emergence of a discrete van Kampen mode means either loss of Landau damping or instability. Longitudinal bunch stability is analysed in weak head-tail approximation for inductive impedance and single-harmonic RF. The LLD threshold intensities are found to be rather low: for cases under study all of them do not exceed a few percent of the zero-amplitude incoherent synchrotron frequency shift, strongly decreasing for shorter bunches. Because of that, LLD can explain longitudinal instabilities happened at fairly low impedances at Tevatron [4], and possibly for RHIC [5] and SPS [6], being in that sense an alternative to the soliton explanation [5, 20]. Although LLD itself results in many cases in emergence of a mode with zero growth rate, any couple-bunch (and sometimes multi-turn) wake would drive instability for that mode, however small this wake is. LLD is similar to a loss of immune system of a living cell, when any microbe becomes fatal for it. The emerging discrete mode is normally very different from the rigid-bunch motion; thus the rigid-mode model significantly overestimates the LLD threshold. The power low of LLD predicted in Ref. [17] agrees with results of this paper. However, the numerical factor in that scaling low strongly depends on the bunch distribution function

  3. Do bees like Van Gogh's Sunflowers?

    NASA Astrophysics Data System (ADS)

    Chittka, Lars; Walker, Julian

    2006-06-01

    Flower colours have evolved over 100 million years to address the colour vision of their bee pollinators. In a much more rapid process, cultural (and horticultural) evolution has produced images of flowers that stimulate aesthetic responses in human observers. The colour vision and analysis of visual patterns differ in several respects between humans and bees. Here, a behavioural ecologist and an installation artist present bumblebees with reproductions of paintings highly appreciated in Western society, such as Van Gogh's Sunflowers. We use this unconventional approach in the hope to raise awareness for between-species differences in visual perception, and to provoke thinking about the implications of biology in human aesthetics and the relationship between object representation and its biological connotations.

  4. Tunnelling in van der Waals heterostructures

    NASA Astrophysics Data System (ADS)

    Mishchenko, Artem; Novoselov, Kostya; Geim, Andre; Eaves, Laurence; Falko, Vladimir

    When graphene and other conductive two-dimensional (2D) materials are separated by an atomically thin insulating 2D crystal, quantum mechanical tunnelling leads to appreciable current between two 2D conductors due to the overlap of their wavefunctions. These tunnel devices demonstrate interesting physics and potential for applications: such effects as resonant tunnelling, negative differential conductance, light emission and detection have already been demonstrated. In this presentation we will outline the current status and perspectives of tunnelling transistors based on 2D materials assembled into van der Waals heterostructures. Particularly, we will present results on mono- and bilayer graphene tunnelling, tunnelling in 2D crystal-based quantum wells, and tunnelling in superconducting 2D materials. Such effects as momentum and chirality conservation, phonon- and impurity-assisted tunnelling will also be discussed. Finally, we will ponder the implications of discovered effects for practical applications.

  5. van Vleck determinants: Traversable wormhole spacetimes

    SciTech Connect

    Visser, M. )

    1994-04-15

    Prompted by various questions regarding the putative existence, stability, and chronological properties of traversable wormholes, a number of authors have presented calculations of the renormalized stress-energy tensor in wormhole spacetimes. In particular, the use of point-splitting techniques leads to expressions that contain the van Vleck determinant as a common prefactor. Recent technical advances permit one to undertake extensive computations of the van Vleck determinant in traversable wormhole spacetimes, at least in the short-throat flat-space approximation. This paper presents several such computations for various model spacetimes. Implications with regard to Hawking's chronology protection conjecture are discussed. In particular, any attempt to transform a single isolated wormhole into a time machine results in large vacuum polarization effects. These vacuum polarization effects are sufficient to disrupt the internal structure of the wormhole long before the onset of Planck scale physics, and before the onset of time travel. Thus for isolated wormholes, vacuum polarization effects are sufficient to enforce Hawking's chronology protection conjecture. On the other hand, it is possible to conceive of a putative time machine built out of two or more wormholes, each of which taken in isolation is not itself a time machine. Such Roman configurations'' are much more subtle to analyze. For reasonable'' configurations (traversable by humans) the vacuum polarization effects in such multiple wormhole putative time machines become large long before the onset of Planck scale physics. The disruption scale for would-be traversable time machines'' is well above the Planck length. On the other hand, for some particularly bizarre configurations (not traversable by humans) the vacuum polarization effects can be arranged to be arbitrarily small at the onset of Planck scale physics.

  6. Biology of Grapsus grapsus (L innaeus, 1758) (Brachyura, Grapsidae) in the Saint Peter and Saint Paul Archipelago, Equatorial Atlantic Ocean

    NASA Astrophysics Data System (ADS)

    Freire, A. S.; Pinheiro, M. A. A.; Karam-Silva, H.; Teschima, M. M.

    2011-09-01

    Eleven expeditions were undertaken to the Saint Peter and Saint Paul Archipelago to study the reproductive biology of Grapsus grapsus, providing additional information on limb mutilation and carapace colour. MATURE software was used to estimate morphological maturity, while gonadal analyses were conducted to estimate physiological maturity. The puberty moult took place at larger size in males (51.4 mm of carapace length) than in females (33.8 mm), while physiological maturity occurred at a similar size in males (38.4 mm) and in females (33.4 mm). Above 50 mm, the proportion of red males increased in the population, indicating that functional maturity is also related to colour pattern. Small habitat and high local population density contributed to the high rate of cannibalism. The low diversity of food items, absence of predators of large crabs and high geographic isolation are the determinants of unique behavioural and biological characteristics observed in the G. grapsus population.

  7. Potential metabolic strategies of widely distributed holobionts in the oceanic archipelago of St Peter and St Paul (Brazil).

    PubMed

    Rua, Cintia P J; Gregoracci, Gustavo B; Santos, Eidy O; Soares, Ana Carolina; Francini-Filho, Ronaldo B; Thompson, Fabiano

    2015-06-01

    Sponges are one of the most complex symbiotic communities and while the taxonomic composition of associated microbes has been determined, the biggest challenge now is to uncover their functional role in symbiosis. We investigated the microbiota of two widely distributed sponge species, regarding both their taxonomic composition and their functional roles. Samples of Didiscus oxeata and Scopalina ruetzleri were collected in the oceanic archipelago of St Peter and St Paul and analysed through metagenomics. Sequences generated by 454 pyrosequencing and Ion Torrent were taxonomically and functionally annotated on the MG-RAST server using the GenBank and SEED databases, respectively. Both communities exhibit equivalence in core functions, interestingly played by the most abundant taxa in each community. Conversely, the microbial communities differ in composition, taxonomic diversity and potential metabolic strategies. Functional annotation indirectly suggests differences in preferential pathways of carbon, nitrogen and sulphur metabolisms, which may indicate different metabolic strategies. PMID:25873456

  8. Occurrences of whale shark (Rhincodon typus Smith, 1828) in the Saint Peter and Saint Paul archipelago, Brazil.

    PubMed

    Hazin, F H V; Vaske Júnior, T; Oliveira, P G; Macena, B C L; Carvalho, F

    2008-05-01

    The Saint Peter and Saint Paul Archipelago in the central tropical Atlantic, is an important ground of whale sharks that are commonly sighted throughout the year close to the fishing boats in the adjacencies of the islands. In sightings reported between February 2000 and November 2005, the lengths of the individuals ranged between 1.8 to 14.0 m. The causes of these concentrations in the archipelago are still unclear, once there are no upwellings and plankton concentrations for feeding, and no reproductive activities were reported. Nevertheless, they could be associated to the spawning period of the abundant flying fishes, mainly in the first semester, when sightings were more frequent. PMID:18660968

  9. The impact of implanted whale carcass on nematode communities in shallow water area of Peter the Great Bay (East Sea)

    NASA Astrophysics Data System (ADS)

    Pavlyuk, Olga N.; Trebukhova, Yulia A.; Tarasov, Vitalyi G.

    2009-09-01

    In May, 2007 we sank the remains of a Minke whale ( Balaenoptera acutorostrata) in the East Sea, Peter the Great Bay, at 30 m of water near the coast of Big Pelis Island. In the present study we describe the nematode communities in sediments under the implanted whale carcass. Abundance of nematodes increased with the distance from the carcass. Dominant trophic group was non-selective deposit feeders. The highest values of indexes of a specific diversity and evenness were noted in sediments under the whale, while domination index occurred at the highest distance from the whale. The suggestion is made that the cause of low density of nematodes in sediments under the whale is an extreme increase in number of macrofaunal animals, and predation and food competition between macro- and meiofauna. The changes noted in nematode assemblages living in an implanted whale in shallow waters are similar to those in deep-sea assemblages.

  10. The extraordinary career of Professor Dr. Simon van Creveld.

    PubMed

    Stoelinga, Paul J W; Berdon, Walter E; Cohen, M Michael

    2014-11-01

    Simon van Creveld received both the MD and PhD degrees and had a multifaceted medical and scientific education at many hospitals and research institutes in the Netherlands, Germany, and the UK. He and his wife were the first to develop insulin for the Netherlands. His major interests were in hemophilia and hemorrhagic disorders, which accounted for 87 of his publications. In 1934, van Creveld demonstrated that a dispersed protein fraction obtained from serum could reduce the clotting time of hemophilic blood. His interest in glycogen storage disease resulted in van Creveld-von Gierke disease for which van Creveld contributed four published articles. The Ellis-van Creveld syndrome, also known as chondroectodermal dysplasia, was published in 1940 and became well known to medical geneticists. During the Nazi occupation of the Netherlands, van Creveld's professorship was taken away from him because he was Jewish. His visits to hospitals of concentration camps to treat babies and give pediatric advice while wearing a Jewish Yellow Star and interacting with SS Commandants in charge, and then leaving can only be described as amazing. After the war, his professorship was returned, and in the same year as his retirement, he established a large Hemophila Treatment and Research Center now known as the Van Creveld Clinic, which celebrated its 40th anniversary in 2005. PMID:25269937

  11. Some Practices and Approaches Are Clearly Better than Others and We Had Better Not Ignore the Differences. A Response to Peter Smagorinsky

    ERIC Educational Resources Information Center

    Hillocks, George, Jr.

    2009-01-01

    Professor Peter Smagorinsky argues that it is time teachers gave up on the idea of best practice in the teaching of English, and the author tends to agree. At the same time, the author differs on certain points. Smagorinsky's premise is based on the idea that all teacher practices have been enculturated through the various experiences, people, and…

  12. Peter Magolda's Proposal for an Unholy Alliance: Cautions and Considerations regarding Collaboration between Student Affairs and Faith-Based Student Organizations

    ERIC Educational Resources Information Center

    Glanzer, Perry L.

    2011-01-01

    In a recent volume of the "Journal of College and Character", Peter Magolda (2010) suggested that student administration professionals and campus religious groups should strive to overcome the separation that has been observed between the groups. In the present article, the author contends that good historical, moral, and legal reasons remain for…

  13. Light and scanning electron microscopic study of the tongue in the estuarine dolphin (Sotalia guianensis van Bénéden, 1864).

    PubMed

    Guimarães, Juliana Plácido; Mari, Renata de Britto; Marigo, Juliana; Rosas, Fernando César Weber; Watanabe, Ii-Sei

    2011-08-01

    The importance of the tongue during feeding, and the limited information on the tongue of most aquatic mammals led us to investigate its morphological aspects in sexually immature and mature Sotalia guianensis. Six tongues were measured and photo-documented after their removal from the oral cavity. The samples were divided into rostral, middle, and caudal regions, and examined using light microscopy and scanning electron microscopy (S.E.M.). Sotalia guianensis tongue presented lateral grooves from the apex to the middle portion, while the anterolateral region presented marginal papillae. Histological characteristics revealed the presence of a keratinized stratified epithelium, salivary glands in the middle and caudal portions of the tongue, and filiform papillae in the caudal region. S.E.M. images revealed the presence of filiform papillae and ducts of salivary glands in the middle and caudal portions of the tongue. We can conclude that the characteristics found in this study may reflect an adaptation to changes in diet after weaning. PMID:21801004

  14. Feeding associations between Guiana dolphins, Sotalia guianensis (Van Bénèden, 1864) and seabirds in the Lagamar estuary, Brazil.

    PubMed

    Santos, M C O; Oshima, J E F; Pacífico, E S; Silva, E

    2010-02-01

    The main objective of the present study was to describe the characteristics regarding interactions between Guiana dolphins, Sotalia guianensis and seabirds in feeding associations in two distinct areas of the Lagamar estuary, Brazil. Boat-based surveys directed towards photo-identification studies of S. guianensis were conducted in the Cananéia Estuary (CE) (25 degrees 01' S and 47 degrees 55' W) from July 2004 to March 2008, as well as in the Paranaguá Estuarine Complex (PEC) (25 degrees 24' S and 48 degrees 24' W) from April 2006 to February 2008. On all occasions when seabirds were observed engaging in multi-species feeding associations with S. guianensis, data on species involved and their numbers were gathered. From 435 observed groups of S. guianensis in the CE, 38 (8.7%) involved interactions with seabirds. In the PEC, from the 286 observed groups, 32 (11.2%) involved the mentioned interactions. The following seabirds were observed in feeding associations with S. guianensis: Fregata magnificens, Sula leucogaster, Phalacrocorax brasilianus, and Sterna sp. In the CE, S. leucogaster was more commonly observed in feeding associations with Guiana dolphins (chi2 = 22.84; d.f. = 3, p < 0.05), while in the PEC no differences were reported when comparing seabird species (chi2 = 5.78; d.f.=3, p = 0.1223). In the CE, feeding associations were significantly more frequent in inner waters (subset A0; chi2 = 9.52; d.f. = 2, p < 0.05), and in winter (chi2 = 12.46; d.f. = 1, p < 0.05). Within these events, 44.7% of the association groups were composed by more than one seabird species. Seasonality in feeding associations was also observed in the PEC (chi2 = 4.76; d.f. = 1, p < 0.05), with same patterns observed in the CE. Interactions were more frequent in inner waters of the Laranjeiras bay, PEC (chi2 = 11.65; d.f. = 2, p < 0.05). Within these events, 74.2% of the association groups were composed by more than one seabird species. Water transparency, prey and seabird abundance and distribution, cetacean group size, and the life cycle of prey and seabirds are listed as the main factors addressing multi-species feeding associations in the Lagamar estuary. PMID:20231955

  15. Behaviour of Sotalia guianensis (van Bénéden, 1864) (Cetacea, Delphinidae) and ethnoecological knowledge of artisanal fishermen from Canavieiras, Bahia, Brazil

    PubMed Central

    2012-01-01

    Artisanal fishermen, because of their direct and frequent contact with the aquatic environment, possess a wealth of knowledge about the natural history of the fauna of the region in which they live. This knowledge, both practical and theoretical, has been frequently utilized and integrated into academic research. Taking this into consideration, this study discusses the ethnoecological knowledge of artisanal fishermen from a community in Canavieiras, state of Bahia, Brazil regarding the Guiana dolphin (Sotalia guianensis), a typically costal member of the family Delphinidae that is little studied in this region. To this end, the behaviour of S. guianensis in Canavieiras was recorded over one year and the data obtained were compared with fishermen’s reports. A total of 609 hours of behavioural observations of S. guianensis was conducted from a fixed point in alternate morning and afternoon sessions between October 2009 and September 2010. Observations were conducted from a pier (15°40’59”S and 38°56’38”W) situated on the banks of the Pardo River estuary - the region’s main river - at 5.5 m above water level. For ethnoecological data collection, semi-structured interviews were carried out with 26 fishermen in May, June and September 2010 and January 2011 in the fishing community of Atalaia. Occasional boat expeditions were made with the fishermen to compare their reports with direct observations of the behaviour of S. guianensis. The results demonstrate that fishermen possess a body of knowledge about S. guianensis that describes in detail the main behavioural aspects of the species. They reported the presence of S. guianensis in the Pardo River estuary throughout the year and its gregarious behaviour. They cited a relationship between the movement of dolphins and tidal cycles, and their presence in the estuary associated with the search for food. In addition, the fishermen reported that numbers of infants in groups were proportional to group size. Behaviours described were compatible with the observations made in situ and with data found in the scientific literature, confirming the importance of traditional knowledge in complementing scientific data. One behaviour mentioned by the fishermen that had no equivalence in the scientific literature was confirmed in situ and, therefore, constitutes the first record for this species. PMID:22584063

  16. Vehicle test report: Jet Industries Electra Van 600

    NASA Technical Reports Server (NTRS)

    Price, T. W.; Wirth, V. A., Jr.

    1982-01-01

    The Electra Van 600, an electric vehicle, was tested. Tests were performed to characterize parameters of the Electra Van 600 and to provide baseline data to be used for comparison of improved batteries and to which will be incorporated into the vehicle. The vehicle tests concentrated on the electrical drive subsystem, the batteries, controller, and motor; coastdowns to characterize the road load and range evaluation for cyclic and constant speed conditions; and qualitative performance was evaluated. It is found that the Electra Van 600 range performance is approximately equal to the majority of the vehicles tested previously.

  17. Transcriptional Regulation of the Vanillate Utilization Genes (vanABK Operon) of Corynebacterium glutamicum by VanR, a PadR-Like Repressor

    PubMed Central

    Lange, Julian; Watzlawick, Hildegard; Kalinowski, Jörn; Altenbuchner, Josef

    2014-01-01

    Corynebacterium glutamicum is able to utilize vanillate, the product of lignin degradation, as the sole carbon source. The vanillate utilization components are encoded by the vanABK operon. The vanA and vanB genes encode the subunits of vanillate O-demethylase, converting vanillate to protocatechuate, while VanK is the specific vanillate transporter. The vanABK operon is regulated by a PadR-type repressor, VanR. Heterologous gene expression and variations of the vanR open reading frame revealed that the functional VanR contains 192 residues (21 kDa) and forms a dimer, as analyzed by size exclusion chromatography. In vivo, ferulate, vanillin, and vanillate induced PvanABK in C. glutamicum, while only vanillate induced the activity of PvanABK in Escherichia coli lacking the ferulate catabolic system. Differential scanning fluorimetry verified that vanillate is the only effector of VanR. Interaction between the PvanABK DNA fragment and the VanR protein had an equilibrium dissociation constant (KD) of 15.1 ± 1.7 nM. The VanR-DNA complex had a dissociation rate constant (Kd) of (267 ± 23) × 10−6 s−1, with a half-life of 43.5 ± 3.6 min. DNase I footprinting localized the VanR binding site at PvanABK, extending from +9 to +45 on the coding strand. Deletion of the nucleotides +18 to +27 inside the VanR binding site rendered PvanABK constitutive. Fusion of the T7 promoter and the wild-type VanR operator, as well as its shortened versions, indicated that the inverted repeat AACTAACTAA(N4)TTAGGTATTT is the specific VanR binding site. It is proposed that the VanR-DNA complex contains two VanR dimers at the VanR operator. PMID:25535273

  18. Transcriptional regulation of the vanillate utilization genes (vanABK Operon) of Corynebacterium glutamicum by VanR, a PadR-like repressor.

    PubMed

    Morabbi Heravi, Kambiz; Lange, Julian; Watzlawick, Hildegard; Kalinowski, Jörn; Altenbuchner, Josef

    2015-03-01

    Corynebacterium glutamicum is able to utilize vanillate, the product of lignin degradation, as the sole carbon source. The vanillate utilization components are encoded by the vanABK operon. The vanA and vanB genes encode the subunits of vanillate O-demethylase, converting vanillate to protocatechuate, while VanK is the specific vanillate transporter. The vanABK operon is regulated by a PadR-type repressor, VanR. Heterologous gene expression and variations of the vanR open reading frame revealed that the functional VanR contains 192 residues (21 kDa) and forms a dimer, as analyzed by size exclusion chromatography. In vivo, ferulate, vanillin, and vanillate induced PvanABK in C. glutamicum, while only vanillate induced the activity of PvanABK in Escherichia coli lacking the ferulate catabolic system. Differential scanning fluorimetry verified that vanillate is the only effector of VanR. Interaction between the PvanABK DNA fragment and the VanR protein had an equilibrium dissociation constant (KD) of 15.1 ± 1.7 nM. The VanR-DNA complex had a dissociation rate constant (Kd) of (267 ± 23) × 10(-6) s(-1), with a half-life of 43.5 ± 3.6 min. DNase I footprinting localized the VanR binding site at PvanABK, extending from +9 to +45 on the coding strand. Deletion of the nucleotides +18 to +27 inside the VanR binding site rendered PvanABK constitutive. Fusion of the T7 promoter and the wild-type VanR operator, as well as its shortened versions, indicated that the inverted repeat AACTAACTAA(N4)TTAGGTATTT is the specific VanR binding site. It is proposed that the VanR-DNA complex contains two VanR dimers at the VanR operator. PMID:25535273

  19. Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model

    PubMed Central

    Hatting, M; Spannbauer, M; Peng, J; Al Masaoudi, M; Sellge, G; Nevzorova, Y A; Gassler, N; Liedtke, C; Cubero, F J; Trautwein, C

    2015-01-01

    Chronic liver inflammation is a crucial event in the development and growth of hepatocellular carcinoma (HCC). Compelling evidence has shown that interleukin-6 (IL-6)/gp130-dependent signaling has a fundamental role in liver carcinogenesis. Thus, in the present study we aimed to investigate the role of gp130 in hepatocytes for the initiation and progression of HCC. Hepatocyte-specific gp130 knockout mice (gp130Δhepa) and control animals (gp130f/f) were treated with diethylnitrosamine (DEN). The role of gp130 for acute injury (0–144 h post treatment), tumor initiation (24 weeks) and progression (40 weeks) was analyzed. After acute DEN-induced liver injury we observed a reduction in the inflammatory response in gp130Δhepa animals as reflected by decreased levels of IL-6 and oncostatin M. The loss of gp130 slightly attenuated the initiation of HCC 24 weeks after DEN treatment. In contrast, 40 weeks after DEN treatment, male and female gp130Δhepa mice showed smaller tumors and reduced tumor burden, indicating a role for hepatocyte-specific gp130 expression during HCC progression. Oxidative stress and DNA damage were substantially and similarly increased by DEN in both gp130f/f and gp130Δhepa animals. However, gp130Δhepa livers revealed aberrant STAT5 activation and decreased levels of transforming growth factor-β (TGFβ), pSMAD2/3 and SMAD2, whereas phosphorylation of STAT3 at Tyr705 and Ser727 was absent. Our results indicate that gp130 deletion in hepatocytes reduces progression, but not HCC initiation in the DEN model. Gp130 deletion resulted in STAT3 inhibition but increased STAT5 activation and diminished TGF-dependent signaling. Hence, blocking gp130 in hepatocytes might be an interesting therapeutic target to inhibit the growth of HCC. PMID:25741592

  20. Treatment of Dens Invagination in a Maxillary Lateral Incisor: A Case Report

    PubMed Central

    Heydari, Azar; Rahmani, Mona

    2015-01-01

    Dens invagination is a developmental anomaly requiring specific treatment approaches. Oehler's Type III dens in dente, extends into the root and perforates at the apical area or lateral surface of the root. In this case endodontic treatment of the invaginated tooth was carried out through the central lumen of the invagination with calcium hydroxide without manipulation of the main pulp canal, thereby leaving the tooth vital. The 18-month follow-up examinations were indicative of treatment success; the periapical lesion resolved completely and the tooth remained vital. Conclusion: Information about the three dimensional anatomy of the teeth especially those with an abnormality is necessary for a successful treatment. PMID:26213545

  1. Mapping polar bear maternal denning habitat in the National Petroleum Reserve -- Alaska with an IfSAR digital terrain model

    USGS Publications Warehouse

    Durner, George M.; Simac, Kristin; Amstrup, Steven C.

    2013-01-01

    The National Petroleum Reserve–Alaska (NPR-A) in northeastern Alaska provides winter maternal denning habitat for polar bears (Ursus maritimus) and also has high potential for recoverable hydrocarbons. Denning polar bears exposed to human activities may abandon their dens before their young are able to survive the severity of Arctic winter weather. To ensure that wintertime petroleum activities do not threaten polar bears, managers need to know the distribution of landscape features in which maternal dens are likely to occur. Here, we present a map of potential denning habitat within the NPR-A. We used a fine-grain digital elevation model derived from Interferometric Synthetic Aperture Radar (IfSAR) to generate a map of putative denning habitat. We then tested the map’s ability to identify polar bear denning habitat on the landscape. Our final map correctly identified 82% of denning habitat estimated to be within the NPR-A. Mapped denning habitat comprised 19.7 km2 (0.1% of the study area) and was widely dispersed. Though mapping denning habitat with IfSAR data was as effective as mapping with the photogrammetric methods used for other regions of the Alaskan Arctic coastal plain, the use of GIS to analyze IfSAR data allowed greater objectivity and flexibility with less manual labor. Analytical advantages and performance equivalent to that of manual cartographic methods suggest that the use of IfSAR data to identify polar bear maternal denning habitat is a better management tool in the NPR-A and wherever such data may be available.

  2. 21. View West, Detail Mural, Children's Room, Rip Van Winkle ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. View West, Detail Mural, Children's Room, Rip Van Winkle Mural, Project of the CWA (Civil Works Administration) Completed May 1934. - Ives Memorial Library, 133 Elm Street, New Haven, New Haven County, CT

  3. 1. Historic American Buildings Survey Cortlandt Van Dyke Hubbard, Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Cortlandt Van Dyke Hubbard, Photographer June 1960 EXTERIOR OF THE SOUTH AND EAST ELEVATIONS - The Judges Law Office, 100 West Market Street, Georgetown, Sussex County, DE

  4. Isotope separation by photodissociation of Van der Waal's molecules

    DOEpatents

    Lee, Yuan T.

    1977-01-01

    A method of separating isotopes based on the dissociation of a Van der Waal's complex. A beam of molecules of a Van der Waal's complex containing, as one partner of the complex, a molecular species in which an element is present in a plurality of isotopes is subjected to radiation from a source tuned to a frequency which will selectively excite vibrational motion by a vibrational transition or through electronic transition of those complexed molecules of the molecular species which contain a desired isotope. Since the Van der Waal's binding energy is much smaller than the excitational energy of vibrational motion, the thus excited Van der Waal's complex dissociate into molecular components enriched in the desired isotope. The recoil velocity associated with vibrational to translational and rotational relaxation will send the separated molecules away from the beam whereupon the product enriched in the desired isotope can be separated from the constituents of the beam.

  5. Genetics Home Reference: Ellis-van Creveld syndrome

    MedlinePlus

    ... bone growth that results in very short stature (dwarfism). People with this condition have particularly short forearms ... Ellis-van Creveld Syndrome Encyclopedia: Polydactyly Health Topic: Dwarfism Genetic and Rare Diseases Information Center (1 link) ...

  6. Electric G-Van demonstration and commercial assessment project

    SciTech Connect

    Braga, B.D. )

    1992-12-01

    The Electric Power Research Institute was awarded this grant to continue the joint effort initiated by EPRI, and VE International to proceed beyond the prototype phase of the electric G-Van development. The goal of EPRI and VEHMA was to develop a market for the electric G-Van, and to distribute them to commercial fleet operators. The objective of this project was to produce G-Vans in a production facility that would be comparable to the GMC Truck internal combustion engine Vandura Van produced by General Motors in quality, reliability, durability and safety. An initial market assessment/demonstration phase of sixty (60) vehicles was to be undertaken, with the ability to expand production volume quickly to meet market demands. Brief description of each task of this grant is given and the actions taken by EPRI to complete them.

  7. Astronaut James D. van Hoften examines student experiment on Challenger

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Astronaut James D. van Hoften, 41-C mission specialist, holds an aluminum box full of honeybees. The experiment in earth orbit is duplicated with another colony of the bees on earth. This is an experiment submitted by student researchers.

  8. STS-42 Earth observation of Lake Van in Turkey

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-42 Earth observation taken aboard Discovery, Orbiter Vehicle (OV) 103, is of Lake Van in Turkey, near the Iranian border (38.5N, 43.0E). Lake Van sits in the middle of a large fault and volcanic zone, the details of which are barely known. Earthquakes, sometimes severe, are frequent in this area. The lake is surrounded by many volcanic cones, calderas and lava plains. Because the climate is semi-arid and the lake has no apparent outlet, scientists say, the lake is relatively alkaline. Lake Van sits at an elevation of 5,400 feet with surrounding mountains completely snow-covered, reaching elevations in excess of 13,000 feet. The city of Van on the eastern edge of the lake shows up well because of the wintertime reflectance contrast between urban development and the snowy countryside.

  9. Measuring a van Hiele Geometry Sequence: A Reanalysis.

    ERIC Educational Resources Information Center

    Wilson, Mark

    1990-01-01

    Summarizes a reanalysis of the data from an investigation of a test designed to measure a learning sequence in geometry based on the work of van Hiele (1986). Discusses the test based on the Rasch model. (YP)

  10. On the Assessment of the Van Hiele Levels of Reasoning.

    ERIC Educational Resources Information Center

    Gutierrez, Angel; Jaime, Adela

    1998-01-01

    Discusses the need for a van Hiele test without limitations. Presents the background and main characteristics of a procedure to select items in designing three linked tests on polygons and other related concepts. Contains 15 references. (ASK)

  11. 1. Historic American Buildings Survey Cortlandt Van Dyke Hubbard, Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Cortlandt Van Dyke Hubbard, Photographer February 1961 FRONT ELEVATION - Baynard House, Lewis Road (moved to MD-Chesapeake City Vicinity), Harrington, Kent County, DE

  12. 2. Historic American Buildings Survey Cortlandt Van Dyke Hubbard, Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey Cortlandt Van Dyke Hubbard, Photographer February 1961 DETACHED KITCHEN - Baynard House, Lewis Road (moved to MD-Chesapeake City Vicinity), Harrington, Kent County, DE

  13. 6. Historic American Buildings Survey Cortlandt Van Dyke Hubbard, Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey Cortlandt Van Dyke Hubbard, Photographer February 1961 DINING ROOM (PRESENT KITCHEN) WITH STAIR AND DOORS TO PARLOR (LEFT) AND BEDROOM - Baynard House, Lewis Road (moved to MD-Chesapeake City Vicinity), Harrington, Kent County, DE

  14. 3. Historic American Buildings Survey Cortlandt Van Dyke Hubbard, Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey Cortlandt Van Dyke Hubbard, Photographer February 1961 MAIN STAIR FROM FIRST FLOOR - Baynard House, Lewis Road (moved to MD-Chesapeake City Vicinity), Harrington, Kent County, DE

  15. 5. Historic American Buildings Survey Cortlandt Van Dyke Hubbard, Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey Cortlandt Van Dyke Hubbard, Photographer February 1961 FIREPLACE AND CUPBOARD IN PARLOR - Baynard House, Lewis Road (moved to MD-Chesapeake City Vicinity), Harrington, Kent County, DE

  16. 4. Historic American Buildings Survey Cortlandt Van Dyke Hubbard, Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey Cortlandt Van Dyke Hubbard, Photographer February 1961 PANELING UNDER WINDOW IN PARLOR - Baynard House, Lewis Road (moved to MD-Chesapeake City Vicinity), Harrington, Kent County, DE

  17. Astronauts van Hoften and Nelson conduct pre-breathing exercise

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Astronauts James D. van Hoften and George D. Nelson, wearing Shuttle launch and entry helmets, conduct a pre-breathing exercise on the forward flight deck of the shuttle Challenger during the STS 41-C mission.

  18. Picosecond photoresponse in van der Waals heterostructures.

    PubMed

    Massicotte, M; Schmidt, P; Vialla, F; Schädler, K G; Reserbat-Plantey, A; Watanabe, K; Taniguchi, T; Tielrooij, K J; Koppens, F H L

    2016-01-01

    Two-dimensional crystals such as graphene and transition-metal dichalcogenides demonstrate a range of unique and complementary optoelectronic properties. Assembling different two-dimensional materials in vertical heterostructures enables the combination of these properties in one device, thus creating multifunctional optoelectronic systems with superior performance. Here, we demonstrate that graphene/WSe2/graphene heterostructures ally the high photodetection efficiency of transition-metal dichalcogenides with a picosecond photoresponse comparable to that of graphene, thereby optimizing both speed and efficiency in a single photodetector. We follow the extraction of photoexcited carriers in these devices using time-resolved photocurrent measurements and demonstrate a photoresponse time as short as 5.5 ps, which we tune by applying a bias and by varying the transition-metal dichalcogenide layer thickness. Our study provides direct insight into the physical processes governing the detection speed and quantum efficiency of these van der Waals heterostuctures, such as out-of-plane carrier drift and recombination. The observation and understanding of ultrafast and efficient photodetection demonstrate the potential of hybrid transition-metal dichalcogenide-based heterostructures as a platform for future optoelectronic devices. PMID:26436565

  19. Van der Waals Interactions Involving Proteins

    NASA Technical Reports Server (NTRS)

    Roth, Charles M.; Neal, Brian L.; Lenhoff, Abraham M.

    1996-01-01

    Van der Waals (dispersion) forces contribute to interactions of proteins with other molecules or with surfaces, but because of the structural complexity of protein molecules, the magnitude of these effects is usually estimated based on idealized models of the molecular geometry, e.g., spheres or spheroids. The calculations reported here seek to account for both the geometric irregularity of protein molecules and the material properties of the interacting media. Whereas the latter are found to fall in the generally accepted range, the molecular shape is shown to cause the magnitudes of the interactions to differ significantly from those calculated using idealized models. with important consequences. First, the roughness of the molecular surface leads to much lower average interaction energies for both protein-protein and protein-surface cases relative to calculations in which the protein molecule is approximated as a sphere. These results indicate that a form of steric stabilization may be an important effect in protein solutions. Underlying this behavior is appreciable orientational dependence, one reflection of which is that molecules of complementary shape are found to exhibit very strong attractive dispersion interactions. Although this has been widely discussed previously in the context of molecular recognition processes, the broader implications of these phenomena may also be important at larger molecular separations, e.g., in the dynamics of aggregation, precipitation, and crystal growth.

  20. Supercurrent in van der Waals Josephson junction

    PubMed Central

    Yabuki, Naoto; Moriya, Rai; Arai, Miho; Sata, Yohta; Morikawa, Sei; Masubuchi, Satoru; Machida, Tomoki

    2016-01-01

    Supercurrent flow between two superconductors with different order parameters, a phenomenon known as the Josephson effect, can be achieved by inserting a non-superconducting material between two superconductors to decouple their wavefunctions. These Josephson junctions have been employed in fields ranging from digital to quantum electronics, yet their functionality is limited by the interface quality and use of non-superconducting material. Here we show that by exfoliating a layered dichalcogenide (NbSe2) superconductor, the van der Waals (vdW) contact between the cleaved surfaces can instead be used to construct a Josephson junction. This is made possible by recent advances in vdW heterostructure technology, with an atomically flat vdW interface free of oxidation and inter-diffusion achieved by eliminating all heat treatment during junction preparation. Here we demonstrate that this artificially created vdW interface provides sufficient decoupling of the wavefunctions of the two NbSe2 crystals, with the vdW Josephson junction exhibiting a high supercurrent transparency. PMID:26830754

  1. Van der Waals interactions involving proteins.

    PubMed Central

    Roth, C M; Neal, B L; Lenhoff, A M

    1996-01-01

    Van der Waals (dispersion) forces contribute to interactions of proteins with other molecules or with surfaces, but because of the structural complexity of protein molecules, the magnitude of these effects is usually estimated based on idealized models of the molecular geometry, e.g., spheres or spheroids. The calculations reported here seek to account for both the geometric irregularity of protein molecules and the material properties of the interacting media. Whereas the latter are found to fall in the generally accepted range, the molecular shape is shown to cause the magnitudes of the interactions to differ significantly from those calculated using idealized models, with important consequences. First, the roughness of the molecular surface leads to much lower average interaction energies for both protein-protein and protein-surface cases relative to calculations in which the protein molecule is approximated as a sphere. These results indicate that a form of steric stabilization may be an important effect in protein solutions. Underlying this behavior is appreciable orientational dependence, one reflection of which is that molecules of complementary shape are found to exhibit very strong attractive dispersion interactions. Although this has been widely discussed previously in the context of molecular recognition processes, the broader implications of these phenomena may also be important at larger molecular separations, e.g., in the dynamics of aggregation, precipitation, and crystal growth. Images FIGURE 3 PMID:8789115

  2. The neuropsychiatric ailment of Vincent Van Gogh

    PubMed Central

    Bhattacharyya, Kalyan B.; Rai, Saurabh

    2015-01-01

    Vincent Van Gogh is one of the most celebrated creative artists of all time. All his life, he was afflicted by some kind of neurological or psychiatric disorder, which remains a mystery even today. Many historians and his personal physicians believe that he suffered from epilepsy while others felt that he was affected by Ménière's disease. Features such as hypergraphia, atypical sexuality, and viscosity of thinking suggest the possibility of Gastaut-Geschwind phenomenon, a known complication of complex partial seizure. On the contrary, some historians feel that he was forced to sever his right ear in order to get relief from troublesome tinnitus, a complication of Ménière's disease. He was addicted to the liquor absinthe, which is known to lead to xanthopsia, and many authorities argue that this was the reason for his penchant for the deep and bright yellow color in many of his paintings. Others have suggested the possibility of bipolar disorder, sunstroke, acute intermittent porphyria, and digitalis toxicity as well. PMID:25745302

  3. Modern theory of van der Waals interactions

    NASA Astrophysics Data System (ADS)

    Dobson, John

    2014-03-01

    van der Waals (vdW, dispersion) interactions are important in diverse areas such as colloid, surface and nano science, cohesion of molecular crystals, and biomolecular science. They also provide competition in experiments to discover the fifth fundamental force.While vdW interactions have been understood in principle for a century, their quantitative first-principles prediction and modelling down to chemical contact separations have proven stubbornly difficult because the quantal many-electron problem is involved. After some brief historical material, the current state of the art will be discussed with particular reference to several approaches: pairwise additive, perturbative quantum chemical, vdW-DF, Lifshitz-like scattering, RPA-like, Adiabatic Connection Fluctuation Dissipation / Time Dependent DFT based etc.. A potentially useful classification will be introduced to aid in understanding the physical causes of departures from pairwise additivity, that is from the usual sum of C6R-6 contributions. These departures result in non-standard power law decays of nanostructure vdW interactions as a function of separation D, as well as surprising dependences of the attraction on the number, N, of atoms within each vdW-interacting fragment. Some further recent results on non-additivity will also be presented. Work supported by an Australian Research Council Discovery Grant.

  4. The neuropsychiatric ailment of Vincent Van Gogh.

    PubMed

    Bhattacharyya, Kalyan B; Rai, Saurabh

    2015-01-01

    Vincent Van Gogh is one of the most celebrated creative artists of all time. All his life, he was afflicted by some kind of neurological or psychiatric disorder, which remains a mystery even today. Many historians and his personal physicians believe that he suffered from epilepsy while others felt that he was affected by Ménière's disease. Features such as hypergraphia, atypical sexuality, and viscosity of thinking suggest the possibility of Gastaut-Geschwind phenomenon, a known complication of complex partial seizure. On the contrary, some historians feel that he was forced to sever his right ear in order to get relief from troublesome tinnitus, a complication of Ménière's disease. He was addicted to the liquor absinthe, which is known to lead to xanthopsia, and many authorities argue that this was the reason for his penchant for the deep and bright yellow color in many of his paintings. Others have suggested the possibility of bipolar disorder, sunstroke, acute intermittent porphyria, and digitalis toxicity as well. PMID:25745302

  5. Picosecond photoresponse in van der Waals heterostructures

    NASA Astrophysics Data System (ADS)

    Massicotte, M.; Schmidt, P.; Vialla, F.; Schädler, K. G.; Reserbat-Plantey, A.; Watanabe, K.; Taniguchi, T.; Tielrooij, K. J.; Koppens, F. H. L.

    2016-01-01

    Two-dimensional crystals such as graphene and transition-metal dichalcogenides demonstrate a range of unique and complementary optoelectronic properties. Assembling different two-dimensional materials in vertical heterostructures enables the combination of these properties in one device, thus creating multifunctional optoelectronic systems with superior performance. Here, we demonstrate that graphene/WSe2/graphene heterostructures ally the high photodetection efficiency of transition-metal dichalcogenides with a picosecond photoresponse comparable to that of graphene, thereby optimizing both speed and efficiency in a single photodetector. We follow the extraction of photoexcited carriers in these devices using time-resolved photocurrent measurements and demonstrate a photoresponse time as short as 5.5 ps, which we tune by applying a bias and by varying the transition-metal dichalcogenide layer thickness. Our study provides direct insight into the physical processes governing the detection speed and quantum efficiency of these van der Waals heterostuctures, such as out-of-plane carrier drift and recombination. The observation and understanding of ultrafast and efficient photodetection demonstrate the potential of hybrid transition-metal dichalcogenide-based heterostructures as a platform for future optoelectronic devices.

  6. Supercurrent in van der Waals Josephson junction

    NASA Astrophysics Data System (ADS)

    Yabuki, Naoto; Moriya, Rai; Arai, Miho; Sata, Yohta; Morikawa, Sei; Masubuchi, Satoru; Machida, Tomoki

    2016-02-01

    Supercurrent flow between two superconductors with different order parameters, a phenomenon known as the Josephson effect, can be achieved by inserting a non-superconducting material between two superconductors to decouple their wavefunctions. These Josephson junctions have been employed in fields ranging from digital to quantum electronics, yet their functionality is limited by the interface quality and use of non-superconducting material. Here we show that by exfoliating a layered dichalcogenide (NbSe2) superconductor, the van der Waals (vdW) contact between the cleaved surfaces can instead be used to construct a Josephson junction. This is made possible by recent advances in vdW heterostructure technology, with an atomically flat vdW interface free of oxidation and inter-diffusion achieved by eliminating all heat treatment during junction preparation. Here we demonstrate that this artificially created vdW interface provides sufficient decoupling of the wavefunctions of the two NbSe2 crystals, with the vdW Josephson junction exhibiting a high supercurrent transparency.

  7. Van der Waals Interactions in Aspirin

    NASA Astrophysics Data System (ADS)

    Reilly, Anthony; Tkatchenko, Alexandre

    2015-03-01

    The ability of molecules to yield multiple solid forms, or polymorphs, has significance for diverse applications ranging from drug design and food chemistry to nonlinear optics and hydrogen storage. In particular, aspirin has been used and studied for over a century, but has only recently been shown to have an additional polymorphic form, known as form II. Since the two observed solid forms of aspirin are degenerate in terms of lattice energy, kinetic effects have been suggested to determine the metastability of the less abundant form II. Here, first-principles calculations provide an alternative explanation based on free-energy differences at room temperature. The explicit consideration of many-body van der Waals interactions in the free energy demonstrates that the stability of the most abundant form of aspirin is due to a subtle coupling between collective electronic fluctuations and quantized lattice vibrations. In addition, a systematic analysis of the elastic properties of the two forms of aspirin rules out mechanical instability of form II as making it metastable.

  8. Dielectric Genome of van der Waals Heterostructures.

    PubMed

    Andersen, Kirsten; Latini, Simone; Thygesen, Kristian S

    2015-07-01

    Vertical stacking of two-dimensional (2D) crystals, such as graphene and hexagonal boron nitride, has recently lead to a new class of materials known as van der Waals heterostructures (vdWHs) with unique and highly tunable electronic properties. Ab initio calculations should in principle provide a powerful tool for modeling and guiding the design of vdWHs, but in their traditional form such calculations are only feasible for commensurable structures with a few layers. Here we show that the dielectric properties of realistic, incommensurable vdWHs comprising hundreds of layers can be efficiently calculated using a multiscale approach where the dielectric functions of the individual layers (the dielectric building blocks) are computed ab initio and coupled together via the long-range Coulomb interaction. We use the method to illustrate the 2D-3D transition of the dielectric function of multilayer MoS2 crystals, the hybridization of quantum plasmons in thick graphene/hBN heterostructures, and to demonstrate the intricate effect of substrate screening on the non-Rydberg exciton series in supported WS2. The dielectric building blocks for a variety of 2D crystals are available in an open database together with the software for solving the coupled electrodynamic equations. PMID:26047386

  9. Supercurrent in van der Waals Josephson junction.

    PubMed

    Yabuki, Naoto; Moriya, Rai; Arai, Miho; Sata, Yohta; Morikawa, Sei; Masubuchi, Satoru; Machida, Tomoki

    2016-01-01

    Supercurrent flow between two superconductors with different order parameters, a phenomenon known as the Josephson effect, can be achieved by inserting a non-superconducting material between two superconductors to decouple their wavefunctions. These Josephson junctions have been employed in fields ranging from digital to quantum electronics, yet their functionality is limited by the interface quality and use of non-superconducting material. Here we show that by exfoliating a layered dichalcogenide (NbSe2) superconductor, the van der Waals (vdW) contact between the cleaved surfaces can instead be used to construct a Josephson junction. This is made possible by recent advances in vdW heterostructure technology, with an atomically flat vdW interface free of oxidation and inter-diffusion achieved by eliminating all heat treatment during junction preparation. Here we demonstrate that this artificially created vdW interface provides sufficient decoupling of the wavefunctions of the two NbSe2 crystals, with the vdW Josephson junction exhibiting a high supercurrent transparency. PMID:26830754

  10. From the corner of Charlie Kelly Blvd. And S. Van ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    From the corner of Charlie Kelly Blvd. And S. Van Valzah St., looking northwest up S. Van Valzah St. Building 604 is in the foreground and to the right of it are buildings 605 and 606. - Fitzsimons General Hospital, Bounded by East Colfax to south, Peoria Street to west, Denver City/County & Adams County Line to north, & U.S. Route 255 to east, Aurora, Adams County, CO

  11. The VAN Method: Contradictory and misleading results since 1981

    NASA Astrophysics Data System (ADS)

    Stavrakakis, George N.; Drakopoulos, John

    We reexamine the VAN-telegrams available to us, in terms of the seismological data observed in the candidate region before and after the relevant telegram. For the time period 1981-1985, the correlations are random. Earthquakes of any magnitude, from an extremely low threshold (i.e., M=2.5) at very short distances (i.e., a few kilometers), to large magnitudes (i.e., M=7.0) at very large distances (i.e., 500 km), or even teleseismic events (i.e., the Iran earthquake of 1981, at a distance of about 2000 km) were correlated by VAN with “apparent” SES, on the basis of the occurrence of an earthquake, anywhere, (from Italy to Aegean Sea, and from Albania to Crete island) and usually based on telegrams exchanged between the VAN-researchers. From 1986 onwards, the VAN-telegrams were restricted mostly to the area of Western Greece, which has the highest seismicity in Europe. By analyzing all of the VAN-telegrams available to us, we conclude that in no case was a mainshock predicted. Whenever the reported VAN-correlation seems to be satisfactory, the correlated event was either an aftershock or the correlation was not unique, meaning that any of several earthquakes in the same focal region could be arbitrarily correlated with the telegram.

  12. VanA-Type MRSA (VRSA) Emerged in Surface Waters.

    PubMed

    Icgen, Bulent

    2016-09-01

    Due to the widespread occurrence of mecA-encoded methicillin resistance in Staphylococcus aureus (MRSA), treatment of staphylococcal infections is shifted to glycopeptide antibiotics like vancomycin and teicoplanin. The selective pressure of glycopeptides has eventually led to the emergence of staphylococci with increased resistance. Of great concern is vanA-encoded high level vancomycin and teicoplanin resistance in MRSA (VRSA). Therefore, this study aimed at investigating the occurrence of VRSA in surface waters. Out of 290, two staphylococcal isolates identified as MRSA Al11, Ba01, and one as MRS Co11 through 16S rRNA sequencing, also displayed high level resistance towards vancomycin and teicoplanin. These staphylococcal isolates were found to harbor vanA gene with sequence similarities of 99 %-100 % to the vanA gene extracted from vancomycin- and teicoplanin-resistant enterococcal (VRE) surface water isolates of Enterococcus faecalis Cr07, E07, Pb06 and E. faecium E330. High level glycopeptide resistance rendering protein encoded by the vanA gene, D-alanine-D-lactate ligase found in VRE, was also shown to be present in all vanA-type staphylococcal isolates through western blot. Current study elucidated that surface waters provide high potential for enterococcal vanA gene being transferred to MRSA, so called VRSA, and require special scientific consideration. PMID:27216737

  13. Margaret Cavendish's materialist critique of van Helmontian chymistry.

    PubMed

    Clucas, Stephen

    2011-03-01

    A striking omission in the scholarship on the reception of the chymical philosophy of Jan Baptista van Helmont in England in the seventeenth century is the work of the mid-seventeenth-century natural philosopher Margaret Cavendish, Duchess of Newcastle. In her Philosophical Letters (1664), Cavendish offers an extended critique of Van Helmont's work (whose Ortus Medicince had recently been translated into English by John Sadler). In this paper, I compare Cavendish's criticisms with those of Robert Boyle in his Sceptical Chymist (1661). Both Boyle and Cavendish attacked Van Helmont for the obscurity of his chymical vocabulary and concepts, and attacked his seminalism. Although their critiques had much in common, they diverged in their attitudes to Van Helmont's experiments. As an opponent of the experimental philosophy, Cavendish had little interest in the quality of Van Helmont's experimental claims, whereas Boyle was critical of their unreplicability. I also try to show that the two writers had very different polemical agendas, with Boyle defending his vision of chymistry based on a corpuscularian natural philosophy, and Cavendish being as much concerned with establishing her religious orthodoxy as with defending the truth claims of her own materialist vitalism. For Cavendish, Van Helmont was an example of the dangers of mingling theology and natural philosophy. PMID:21797072

  14. First evidence of gregarious denning in opossums (Didelphimorphia, Didelphidae), with notes on their social behaviour

    PubMed Central

    Astúa, Diego; Carvalho, Rafael A.; Maia, Paula F.; Magalhães, Arthur R.; Loretto, Diogo

    2015-01-01

    The Didelphidae are considered solitary opossums with few social interactions, usually limited to mating-related or mother–pouch young interactions. Anecdotal reports suggest that additional interactions occur, including den sharing by a few individuals, usually siblings. Here, we report novel observations that indicate opossums are more social than previously thought. These include nest sharing by males and females of Marmosa paraguayana, Gracilinanus microtarsus and Marmosops incanus prior to the onset of the breeding season and without signs of sexual activity; this is taken to indicate early pair-bonding matching and cooperative nest building. We also recorded den sharing among recently weaned siblings of Didelphis aurita and Caluromys philander. In addition, we observed 13 individuals of Didelphis albiventris representing three age classes resting without agonistic interactions in a communal den. These are the first reports of gregarious behaviour involving so many individuals, which are either unrelated or represent siblings from at least two litters, already weaned, sharing the same den with three adults. Sociality in opossums is probably more complex than previously established, and field experimental designs combining the use of artificial nests with camera traps or telemetry may help to gauge the frequency and extent of these phenomena. PMID:26085500

  15. "Where's the Bear? Over There!"--Creative Thinking and Imagination in Den Making

    ERIC Educational Resources Information Center

    Canning, Natalie

    2013-01-01

    This small scale research project examines opportunities for creative thinking and imagination through den making in a rural private day nursery with its own woodland area on the borders of England and Wales in the UK. The research is underpinned by sociocultural theory and is an ethnographic study of non-participant observations of children aged…

  16. The Influence of the Outdoor Environment: Den-Making in Three Different Contexts

    ERIC Educational Resources Information Center

    Canning, Natalie

    2010-01-01

    This small-scale research examined den-making in three different settings in the UK. The research consisted of non-participant, narrative observations of children aged between 3- and 5-years and early years practitioners involved in supporting them in their play. Content analysis revealed common themes: the impact of the environment on the way…

  17. First report of captive New Guinea dingo (Canis dingo hallstromi) den-digging and parental behavior.

    PubMed

    Koler-Matznick, Janice; Stinner, Mindy

    2011-01-01

    New Guinea dingoes (NGDs) (Canis dingo hallstromi; Troughton [1957] Proc Roy Soc new South Wells 1955-1956:93-94) have been kept in zoos since 1956. Almost nothing is known of their wild behavior. These observations of a captive pair are the first documentation of natal den-digging and parental behavior for this taxon. The main den, excavated near the top of a 1.5 m hill, consisted of a rounded chamber about 50.8 cm deep, with an entrance about 30.5 cm high and 40.6 cm wide. The dam frequently moved the pups from the natal den to secondary locations for short periods during the day and then back to the den, starting when the pups were 2 weeks old. When the pups were between 5 and 12 weeks of age, both parents regularly regurgitated for them. The sire expressed escalating threat behavior toward the male pup starting when the pup was 5 months old, and the female began threatening the female pups at about 6 months of age. Rejection of same-sex offspring is usual for captive NGDs as the next breeding season approaches. PMID:21154450

  18. Effect of age on respiratory carcinogenesis with diethyl-nitrosamine (DEN) in hamsters

    SciTech Connect

    Stinson, S.F.; Saffiotti, U.

    1986-03-01

    Groups of male and female Syrian golden hamsters were given 12 weekly s.c. injections of 10 mg/kg DEN beginning at 1 day (85 animals) or 8 weeks (70 animals) of age, and were held for lifetime observation. In hamsters receiving DEN from birth, the first respiratory tumors were observed at 15 experimental weeks; all animals were dead by 66 weeks with a 99% respiratory tumor incidence. Of these hamster, 87% developed carcinomas or adenomas in the nasal cavities, 75% papillomas of the trachea, larynx or extrapulmonary bronchi and 7% adenomas or adenocarcinomas of the peripheral lung. Hamsters given DEN from 8 weeks of age first showed respiratory tumors after 25 weeks with a 96% incidence by 62 weeks when all had died. Of these hamsters, 24% developed carcinomas or adenomas in the nasal cavities, 91% papillomas of the trachea, larynx or bronchi, and 9% adenomas or adenocarcinomas of the peripheral lung. In comparison, the nasal tumors in the first group were more anaplastic and invaded the brain more frequently than in the second. These results indicate that the nasal mucosa of newborns is more sensitive to carcinogenesis with DEN than is that of adults, while there appears to be little age-related susceptibility of the epithelium of the airways or lung. A serial sacrifice experiment is currently under way to study the cells of origin of the various tumors using immuno-histochemical and electron microscopic techniques.

  19. First evidence of gregarious denning in opossums (Didelphimorphia, Didelphidae), with notes on their social behaviour.

    PubMed

    Astúa, Diego; Carvalho, Rafael A; Maia, Paula F; Magalhães, Arthur R; Loretto, Diogo

    2015-06-01

    The Didelphidae are considered solitary opossums with few social interactions, usually limited to mating-related or mother-pouch young interactions. Anecdotal reports suggest that additional interactions occur, including den sharing by a few individuals, usually siblings. Here, we report novel observations that indicate opossums are more social than previously thought. These include nest sharing by males and females of Marmosa paraguayana, Gracilinanus microtarsus and Marmosops incanus prior to the onset of the breeding season and without signs of sexual activity; this is taken to indicate early pair-bonding matching and cooperative nest building. We also recorded den sharing among recently weaned siblings of Didelphis aurita and Caluromys philander. In addition, we observed 13 individuals of Didelphis albiventris representing three age classes resting without agonistic interactions in a communal den. These are the first reports of gregarious behaviour involving so many individuals, which are either unrelated or represent siblings from at least two litters, already weaned, sharing the same den with three adults. Sociality in opossums is probably more complex than previously established, and field experimental designs combining the use of artificial nests with camera traps or telemetry may help to gauge the frequency and extent of these phenomena. PMID:26085500

  20. DenHunt - A Comprehensive Database of the Intricate Network of Dengue-Human Interactions.

    PubMed

    Karyala, Prashanthi; Metri, Rahul; Bathula, Christopher; Yelamanchi, Syam K; Sahoo, Lipika; Arjunan, Selvam; Sastri, Narayan P; Chandra, Nagasuma

    2016-09-01

    Dengue virus (DENV) is a human pathogen and its etiology has been widely established. There are many interactions between DENV and human proteins that have been reported in literature. However, no publicly accessible resource for efficiently retrieving the information is yet available. In this study, we mined all publicly available dengue-human interactions that have been reported in the literature into a database called DenHunt. We retrieved 682 direct interactions of human proteins with dengue viral components, 382 indirect interactions and 4120 differentially expressed human genes in dengue infected cell lines and patients. We have illustrated the importance of DenHunt by mapping the dengue-human interactions on to the host interactome and observed that the virus targets multiple host functional complexes of important cellular processes such as metabolism, immune system and signaling pathways suggesting a potential role of these interactions in viral pathogenesis. We also observed that 7 percent of the dengue virus interacting human proteins are also associated with other infectious and non-infectious diseases. Finally, the understanding that comes from such analyses could be used to design better strategies to counteract the diseases caused by dengue virus. The whole dataset has been catalogued in a searchable database, called DenHunt (http://proline.biochem.iisc.ernet.in/DenHunt/). PMID:27618709

  1. The Dens: Normal Development, Developmental Variants and Anomalies, and Traumatic Injuries.

    PubMed

    O'Brien, William T; Shen, Peter; Lee, Paul

    2015-01-01

    Accurate interpretation of cervical spine imagining can be challenging, especially in children and the elderly. The biomechanics of the developing pediatric spine and age-related degenerative changes predispose these patient populations to injuries centered at the craniocervical junction. In addition, congenital anomalies are common in this region, especially those associated with the axis/dens, due to its complexity in terms of development compared to other vertebral levels. The most common congenital variations of the dens include the os odontoideum and a persistent ossiculum terminale. At times, it is necessary to distinguish normal development, developmental variants, and developmental anomalies from traumatic injuries in the setting of acute traumatic injury. Key imaging features are useful to differentiate between traumatic fractures and normal or variant anatomy acutely; however, the radiologist must first have a basic understanding of the spectrum of normal developmental anatomy and its anatomic variations in order to make an accurate assessment. This review article attempts to provide the basic framework required for accurate interpretation of cervical spine imaging with a focus on the dens, specifically covering the normal development and ossification of the dens, common congenital variants and their various imaging appearances, fracture classifications, imaging appearances, and treatment options. PMID:26199787

  2. The Dens: Normal Development, Developmental Variants and Anomalies, and Traumatic Injuries

    PubMed Central

    O’Brien, William T; Shen, Peter; Lee, Paul

    2015-01-01

    Accurate interpretation of cervical spine imagining can be challenging, especially in children and the elderly. The biomechanics of the developing pediatric spine and age-related degenerative changes predispose these patient populations to injuries centered at the craniocervical junction. In addition, congenital anomalies are common in this region, especially those associated with the axis/dens, due to its complexity in terms of development compared to other vertebral levels. The most common congenital variations of the dens include the os odontoideum and a persistent ossiculum terminale. At times, it is necessary to distinguish normal development, developmental variants, and developmental anomalies from traumatic injuries in the setting of acute traumatic injury. Key imaging features are useful to differentiate between traumatic fractures and normal or variant anatomy acutely; however, the radiologist must first have a basic understanding of the spectrum of normal developmental anatomy and its anatomic variations in order to make an accurate assessment. This review article attempts to provide the basic framework required for accurate interpretation of cervical spine imaging with a focus on the dens, specifically covering the normal development and ossification of the dens, common congenital variants and their various imaging appearances, fracture classifications, imaging appearances, and treatment options. PMID:26199787

  3. Geological Carbon Sequestration Storage Resource Estimates for the Ordovician St. Peter Sandstone, Illinois and Michigan Basins, USA

    SciTech Connect

    Barnes, David; Ellett, Kevin; Leetaru, Hannes

    2014-09-30

    The Cambro-Ordovician strata of the Midwest of the United States is a primary target for potential geological storage of CO2 in deep saline formations. The objective of this project is to develop a comprehensive evaluation of the Cambro-Ordovician strata in the Illinois and Michigan Basins above the basal Mount Simon Sandstone since the Mount Simon is the subject of other investigations including a demonstration-scale injection at the Illinois Basin Decatur Project. The primary reservoir targets investigated in this study are the middle Ordovician St Peter Sandstone and the late Cambrian to early Ordovician Knox Group carbonates. The topic of this report is a regional-scale evaluation of the geologic storage resource potential of the St Peter Sandstone in both the Illinois and Michigan Basins. Multiple deterministic-based approaches were used in conjunction with the probabilistic-based storage efficiency factors published in the DOE methodology to estimate the carbon storage resource of the formation. Extensive data sets of core analyses and wireline logs were compiled to develop the necessary inputs for volumetric calculations. Results demonstrate how the range in uncertainty of storage resource estimates varies as a function of data availability and quality, and the underlying assumptions used in the different approaches. In the simplest approach, storage resource estimates were calculated from mapping the gross thickness of the formation and applying a single estimate of the effective mean porosity of the formation. Results from this approach led to storage resource estimates ranging from 3.3 to 35.1 Gt in the Michigan Basin, and 1.0 to 11.0 Gt in the Illinois Basin at the P10 and P90 probability level, respectively. The second approach involved consideration of the diagenetic history of the formation throughout the two basins and used depth-dependent functions of porosity to derive a more realistic spatially variable model of porosity rather than applying a

  4. Geologic and Geophysicsal Studies of Natural Hazards and Risks in the Gulf of Peter the Great, Japan Sea

    NASA Astrophysics Data System (ADS)

    Anokhin, Vladimir; Shcherbakov, Viktor; Motychko, Viktor; Slinchenkov, Vladimir; Sokolov, Georgy; Kotov, Sergey; Kartashov, Sergey

    2013-04-01

    The area of the Gulf of Peter the Great is socially, economically and culturally one of the most important regions for the Russian Far East. At the same time, there have been reported palpable natural hazards, which pose a real threat to local infrastructure. Complex field team of the Gramaberg VNIIOkeangeologia institute carried out geological and geophysical studies of natural hazards in the water area and coastal zone of the gulf in the summer and autumn of 2012. The research program included - geodetic deformation monitoring of the coastal zone by the HDS 3000 Leica tachometer; - echo sounding of the underwater part of the coastal slope by the LCX-37C depth sounder equipped with active external 12-channel GPS Lowrance antenna LGC-3000; - high-frequency acoustic profiling by GeoPulse Subbotom Profilier with oscillator frequency of 12.2 kHz for the study of bottom sediments to a depth of 40 m; - hydromagnetic measurements by SeaSPY Marine Magnetics magnetometer for investigation of deep geological structure; - sonar measurements by GEO SM C-MAX, 325 kHz frequency emitters for studying seafloor features; - studies of the water column (sensing and sampling); - bottom sediment sampling. Analytic work was performed by mass spectrometry, atomic absorption spectrophotometry, chromatography, gas chromatography-mass spectrometry, gamma spectrometry and included the following. For water - the content of Fe, Mn, Cd, As, Pb, Cu, Co, Ni, Cr, Zn, Hg in solution and in suspension, polycyclic aromatic compounds, organochlorine pesticides, oil, methane. For sediments - grade analysis, mineralogical analysis of sand, determination of Fe, Mn, Cd, As, Pb, Cu, Co, Ni, Cr, Zn, Hg content; identification of petroleum products, polychlorinated biphenyls, organochlorine pesticides, the specific activity of Cs-137. As a result, a set of geological maps was composed: maps of pre-Quaternary and Quaternary rocks and deposits, lithological map, geomorphological map, map of engineering

  5. van't Hoff-van der Waals osmotic pressure and energy transformers.

    PubMed

    Zener, C; Levenson, W

    1983-07-01

    We find the van't Hoff relations between osmotic pressure, freezing point depression, and boiling point elevation provide a clue on how, by using salt solutions, one may lower the cost of extracting power from low-grade heat sources. In particular, the ratio of 7 between the heat of evaporation and the heat of freezing of pure water suggests a chemical system that raises 7-fold the temperature difference between heat source and heat sink, while decreasing by the same factor the heat flux. Heat exchangers dominate the cost of heat engines operating upon low-grade heat. Their area for a fixed power output is inversely proportional to the available temperature differential. Herein lies the potential for a great cost reduction. We show that the simple van der Waals concept of a gas of hard elastic spheres suffices to understand the colligative properties of salt solutions, at least up to the concentration of the eutectic composition. This concept enables us to physically interpret the thermodynamic processes during the concentration of salt solutions by evaporation and during the mixing of ice and solid salt hydrates at their eutectic temperature. These are identical to the thermodynamic processes taking place during the isothermal compression and expansion of gases in pumps and in turbines. PMID:16593343

  6. van't Hoff-van der Waals osmotic pressure and energy transformers

    PubMed Central

    Zener, Clarence; Levenson, William

    1983-01-01

    We find the van't Hoff relations between osmotic pressure, freezing point depression, and boiling point elevation provide a clue on how, by using salt solutions, one may lower the cost of extracting power from low-grade heat sources. In particular, the ratio of 7 between the heat of evaporation and the heat of freezing of pure water suggests a chemical system that raises 7-fold the temperature difference between heat source and heat sink, while decreasing by the same factor the heat flux. Heat exchangers dominate the cost of heat engines operating upon low-grade heat. Their area for a fixed power output is inversely proportional to the available temperature differential. Herein lies the potential for a great cost reduction. We show that the simple van der Waals concept of a gas of hard elastic spheres suffices to understand the colligative properties of salt solutions, at least up to the concentration of the eutectic composition. This concept enables us to physically interpret the thermodynamic processes during the concentration of salt solutions by evaporation and during the mixing of ice and solid salt hydrates at their eutectic temperature. These are identical to the thermodynamic processes taking place during the isothermal compression and expansion of gases in pumps and in turbines. PMID:16593343

  7. Brown-Vialetto-Van Laere syndrome.

    PubMed

    Sathasivam, Sivakumar

    2008-01-01

    The Brown-Vialetto-Van Laere syndrome (BVVL) is a rare neurological disorder characterized by progressive pontobulbar palsy associated with sensorineural deafness. Fifty-eight cases have been reported in just over 100 years. The female to male ratio is approximately 3:1. The age of onset of the initial symptom varies from infancy to the third decade. The syndrome most frequently presents with sensorineural deafness, which is usually progressive and severe. Lower cranial nerve involvement and lower and upper motor neuron limb signs are common neurological features. Other features include respiratory compromise (the most frequent non-neurological finding), limb weakness, slurring of speech, facial weakness, and neck and shoulder weakness. Optic atrophy, retinitis pigmentosa, macular hyperpigmentation, autonomic dysfunction, epilepsy may occur. The etiopathogenesis of the condition remains elusive. Approximately 50% of cases are familial, of which autosomal recessive is suggested. The remaining cases are sporadic. The diagnosis is usually based on the clinical presentation. Investigations (neurophysiological studies, magnetic resonance imaging of the brain, muscle biopsy, cerebrospinal fluid examination) are done to exclude other causes or to confirm the clinical findings. The differential diagnoses include the Fazio-Londe syndrome, amyotrophic lateral sclerosis, Nathalie syndrome, Boltshauser syndrome and Madras motor neuron disease. Treatment with steroids or intravenous immunoglobulin may result in temporary stabilization of the syndrome. However, the mainstays of management are supportive and symptomatic treatment, in particular assisted ventilation and maintenance of nutrition via gastrostomy. The clinical course of BVVL is variable and includes gradual deterioration (almost half of cases), gradual deterioration with stable periods in between (a third of cases) and deterioration with abrupt periods of worsening (just under a fifth of cases). After the initial

  8. Correction to Van Moorselaar et al. (2015).

    PubMed

    2015-11-01

    Reports an error in "Forgotten But Not Gone: Retro-Cue Costs and Benefits in a Double-Cueing Paradigm Suggest Multiple States in Visual Short-Term Memory" by Dirk van Moorselaar, Christian N. L. Olivers, Jan Theeuwes, Victor A. F. Lamme and Ilja G. Sligte (Journal of Experimental Psychology: Learning, Memory, and Cognition, Advanced Online Publication, Apr 13, 2015, np). The Figure 2 (b) legend printed incorrectly. The correct figure is present in the erratum. All versions of this article have been corrected. (The following abstract of the original article appeared in record 2015-15672-001.) Visual short-term memory (VSTM) performance is enhanced when the to-be-tested item is cued after encoding. This so-called retro-cue benefit is typically accompanied by a cost for the noncued items, suggesting that information is lost from VSTM upon presentation of a retrospective cue. Here we assessed whether noncued items can be restored to VSTM when made relevant again by a subsequent second cue. We presented either 1 or 2 consecutive retro-cues (80% valid) during the retention interval of a change-detection task. Relative to no cue, a valid cue increased VSTM capacity by 2 items, while an invalid cue decreased capacity by 2. Importantly, when a second, valid cue followed an invalid cue, capacity regained 2 items, so that performance was back on par. In addition, when the second cue was also invalid, there was no extra loss of information from VSTM, suggesting that those items that survived a first invalid cue, automatically also survived a second. We conclude that these results are in support of a very versatile VSTM system, in which memoranda adopt different representational states depending on whether they are deemed relevant now, in the future, or not at all. We discuss a neural model that is consistent with this conclusion. PMID:26213836

  9. Van de Graaff based positron source production

    NASA Astrophysics Data System (ADS)

    Lund, Kasey Roy

    The anti-matter counterpart to the electron, the positron, can be used for a myriad of different scientific research projects to include materials research, energy storage, and deep space flight propulsion. Currently there is a demand for large numbers of positrons to aid in these mentioned research projects. There are different methods of producing and harvesting positrons but all require radioactive sources or large facilities. Positron beams produced by relatively small accelerators are attractive because they are easily shut down, and small accelerators are readily available. A 4MV Van de Graaff accelerator was used to induce the nuclear reaction 12C(d,n)13N in order to produce an intense beam of positrons. 13N is an isotope of nitrogen that decays with a 10 minute half life into 13C, a positron, and an electron neutrino. This radioactive gas is frozen onto a cryogenic freezer where it is then channeled to form an antimatter beam. The beam is then guided using axial magnetic fields into a superconducting magnet with a field strength up to 7 Tesla where it will be stored in a newly designed Micro-Penning-Malmberg trap. Several source geometries have been experimented on and found that a maximum antimatter beam with a positron flux of greater than 0.55x10 6 e+s-1 was achieved. This beam was produced using a solid rare gas moderator composed of krypton. Due to geometric restrictions on this set up, only 0.1-1.0% of the antimatter was being frozen to the desired locations. Simulations and preliminary experiments suggest that a new geometry, currently under testing, will produce a beam of 107 e+s-1 or more.

  10. Brown-Vialetto-Van Laere syndrome

    PubMed Central

    Sathasivam, Sivakumar

    2008-01-01

    The Brown-Vialetto-Van Laere syndrome (BVVL) is a rare neurological disorder characterized by progressive pontobulbar palsy associated with sensorineural deafness. Fifty-eight cases have been reported in just over 100 years. The female to male ratio is approximately 3:1. The age of onset of the initial symptom varies from infancy to the third decade. The syndrome most frequently presents with sensorineural deafness, which is usually progressive and severe. Lower cranial nerve involvement and lower and upper motor neuron limb signs are common neurological features. Other features include respiratory compromise (the most frequent non-neurological finding), limb weakness, slurring of speech, facial weakness, and neck and shoulder weakness. Optic atrophy, retinitis pigmentosa, macular hyperpigmentation, autonomic dysfunction, epilepsy may occur. The etiopathogenesis of the condition remains elusive. Approximately 50% of cases are familial, of which autosomal recessive is suggested. The remaining cases are sporadic. The diagnosis is usually based on the clinical presentation. Investigations (neurophysiological studies, magnetic resonance imaging of the brain, muscle biopsy, cerebrospinal fluid examination) are done to exclude other causes or to confirm the clinical findings. The differential diagnoses include the Fazio-Londe syndrome, amyotrophic lateral sclerosis, Nathalie syndrome, Boltshauser syndrome and Madras motor neuron disease. Treatment with steroids or intravenous immunoglobulin may result in temporary stabilization of the syndrome. However, the mainstays of management are supportive and symptomatic treatment, in particular assisted ventilation and maintenance of nutrition via gastrostomy. The clinical course of BVVL is variable and includes gradual deterioration (almost half of cases), gradual deterioration with stable periods in between (a third of cases) and deterioration with abrupt periods of worsening (just under a fifth of cases). After the initial

  11. Mesophotic reef fish assemblages of the remote St. Peter and St. Paul's Archipelago, Mid-Atlantic Ridge, Brazil

    NASA Astrophysics Data System (ADS)

    Rosa, Marcos Rogerio; Alves, Aline Cristina; Medeiros, Diego Valverde; Coni, Ericka Oliveira Cavalcanti; Ferreira, Camilo Moitinho; Ferreira, Beatrice Padovani; de Souza Rosa, Ricardo; Amado-Filho, Gilberto Menezes; Pereira-Filho, Guilherme Henrique; de Moura, Rodrigo Leão; Thompson, Fabiano Lopes; Sumida, Paulo Yukio Gomes; Francini-Filho, Ronaldo Bastos

    2016-03-01

    Mesophotic reef fish assemblages (30-90 m depth) of the small and remote St. Peter and St. Paul's Archipelago (SPSPA), Mid-Atlantic Ridge, Brazil, were characterized using remotely operated vehicles. Ordination analyses identified distinct fish assemblages in the upper (30-50 m) and lower (50-90 m) mesophotic zones, the former characterized by high abundances of species that are also abundant at euphotic reefs ( Caranx lugubris, Melichthys niger, Stegastes sanctipauli and Chromis multilineata) and the latter dominated by two mesophotic specialists ( Prognathodes obliquus and Chromis enchrysura). Planktivores dominated fish assemblages, particularly in the upper mesophotic zone, possibly due to a greater availability of zooplankton coming from the colder Equatorial Undercurrent in mesophotic depths of the SPSPA. Turf algae, fleshy macroalgae and scleractinian corals dominated benthic assemblages between 30 and 40 m depth, while bryozoans, black corals and sponges dominated between 40 and 90 m depth. Canonical correspondence analysis explained 74 % of the relationship between environmental characteristics (depth, benthic cover and complexity) and structure of fish assemblages, with depth as the most important independent variable. Juveniles of Bodianus insularis and adults of P. obliquus and C. enchrysura were clearly associated with branching black corals ( Tanacetipathes spp.), suggesting that black corals play key ecological roles in lower mesophotic reefs of the SPSPA. Results from this study add to the global database about mesophotic reef ecosystems (MREs) and provide a baseline for future evaluations of possible anthropogenic and natural disturbances on MREs of the SPSPA.

  12. A variation on forced migration: Wilhelm Peters (Prussia via Britain to Turkey) and Muzafer Sherif (Turkey to the United States).

    PubMed

    Russell, Gül

    2016-01-01

    In 1933 the Turkish Republic formally offered university positions to 30 German-speaking academics who were dismissed with the coming to power of the National Socialist Government. That initial number went up to 56 with the inclusion of the technical assistants. By 1948 the estimated total had increased to 199. Given renewable five-year contracts with salaries substantially higher than their Turkish counterparts, the foreign émigrés were to implement the westernization program of higher education. The ten year-old secular Turkish Republic's extensive social reforms had encompassed the adoption of the Latin alphabet, and equal rights for women, removing gender bias in hiring. Such a high concentration of émigré academics in one institution, "the highest anywhere in the world," provides a unique opportunity to study a subject which has been neglected. In this article two cases in psychology will be examined: Wilhelm Peters (1880-1963), who came, via Britain, to Istanbul in 1936 from the University of Jena in Germany, and Muzafer Sherif (1906-1988) who went to the United States from Ankara University in 1945. The purpose of the comparative analysis is to identify the features that are specific to the German experience, and those that are shared and underlie translocation in science within the multifaceted complexity of the process of forced migration. PMID:27388256

  13. Theoretical claims necessitate basic research: reply to Gawronski, Lebel, Peters, and Banse (2009) and Nosek and Greenwald (2009).

    PubMed

    De Houwer, Jan; Teige-Mocigemba, Sarah; Spruyt, Adriaan; Moors, Agnes

    2009-05-01

    The authors of this reply article note that B. Gawronski, E. P. LeBel, K. R. Peters, and R. Banse (a) expressed agreement in their comment with the analysis put forward in the target article (J. De Houwer, S. Teige-Mocigemba, A. Spruyt, & A. Moors) and (b) pointed to a further implication for the way in which the implicitness of a measure should be examined. The current authors note that B. A. Nosek and A. G. Greenwald, on the other hand, raised questions in their comment about the definition of the concept "implicit" in the target article, arguing for a fundamentally different approach to measurement that emphasizes not theoretical understanding but usefulness for predicting behavior. In this reply, the current authors respond to these comments and argue that when theoretical claims are made about measures, these claims should be backed up with appropriate evidence. In the absence of basic research, measures and their relation to behavior can only be described. (PsycINFO Database Record (c) 2009 APA, all rights reserved). PMID:19379021

  14. The expression of selected genes linked to metabolic homeostasis in obese pansteatitis-suffering Mozambique tilapia, Oreochromis mossambicus (Peters).

    PubMed

    Truter, J C; van Wyk, J H; Oberholster, P J; Botha, A-M; Luus-Powell, W J

    2016-01-01

    The Oreochromis mossambicus (Peters) population inhabiting Lake Loskop, South Africa, is characterized by a high incidence of obesity and pansteatitis. We investigated potential links between the impaired health of Lake Loskop O. mossambicus and the endocrine system by assessing the expression of selected genes associated with the thyroid and adrenal endocrine axes as well as peroxisome proliferator-activated receptor gamma (pparg). Moreover, contaminant-induced thyroid and/or metabolic modulation in Lake Loskop water was evaluated using juvenile O. mossambicus in laboratory exposures. The expression of thyroid hormone receptor alpha (thra) and type 2 deiodinase (dio2) was higher in Lake Loskop O. mossambicus than fish from another population, suggesting a degree of thyroid disruption. The altered gene expression may be a consequence, rather than cause of obesity. Expression of dio2 and pparg was higher in juvenile O. mossambicus exposed to unfiltered compared to filtered lake water, and our data suggest fasting as causative factor. Micro-organism abundance can therefore be a confounding factor in studies applying molecular markers to test for thyroid modulation by environmental waters. Pansteatitis was not a significant source of variance in the expression of any of the genes investigated, suggesting that the disease is not associated with disrupted endocrine signalling. PMID:25413848

  15. The Wnt Target Protein Peter Pan Defines a Novel p53-independent Nucleolar Stress-Response Pathway.

    PubMed

    Pfister, Astrid S; Keil, Marina; Kühl, Michael

    2015-04-24

    Proper ribosome formation is a prerequisite for cell growth and proliferation. Failure of this process results in nucleolar stress and p53-mediated apoptosis. The Wnt target Peter Pan (PPAN) is required for 45 S rRNA maturation. So far, the role of PPAN in nucleolar stress response has remained elusive. We demonstrate that PPAN localizes to mitochondria in addition to its nucleolar localization and inhibits the mitochondrial apoptosis pathway in a p53-independent manner. Loss of PPAN induces BAX stabilization, depolarization of mitochondria, and release of cytochrome c, demonstrating its important role as an anti-apoptotic factor. Staurosporine-induced nucleolar stress and apoptosis disrupt nucleolar PPAN localization and induce its accumulation in the cytoplasm. This is accompanied by phosphorylation and subsequent cleavage of PPAN by caspases. Moreover, we show that PPAN is a novel interaction partner of the anti-apoptotic protein nucleophosmin (NPM). PPAN depletion induces NPM and upstream-binding factor (UBF) degradation, which is independent of caspases. In summary, we provide evidence for a novel nucleolar stress-response pathway involving PPAN, NPM, and BAX to guarantee cell survival in a p53-independent manner. PMID:25759387

  16. Peter Pan functions independently of its role in ribosome biogenesis during early eye and craniofacial cartilage development in Xenopus laevis.

    PubMed

    Bugner, Verena; Tecza, Aleksandra; Gessert, Susanne; Kühl, Michael

    2011-06-01

    The Xenopus oocyte possesses a large maternal store of ribosomes, thereby uncoupling early development from the de novo ribosome biosynthesis required for cell growth. Brix domain-containing proteins, such as Peter Pan (PPan), are essential for eukaryotic ribosome biogenesis. In this study, we demonstrate that PPan is expressed maternally as well as in the eye and cranial neural crest cells (NCCs) during early Xenopus laevis development. Depletion of PPan and interference with rRNA processing using antisense morpholino oligonucleotides resulted in eye and cranial cartilage malformations. Loss of PPan, but not interference with rRNA processing, led to an early downregulation of specific marker genes of the eye, including Rx1 and Pax6, and of NCCs, such as Twist, Slug and FoxD3. We found that PPan protein is localized in the nucleoli and mitochondria and that loss of PPan results in increased apoptosis. These findings indicate a novel function of PPan that is independent of its role in ribosome biogenesis. PMID:21558383

  17. The business against case revolution. An interview with Nestlé's Peter Brabeck. Interview by Sue Wetlaufer.

    PubMed

    Brabeck, P

    2001-02-01

    One of the world's most enduring companies, Nestle epitomizes everything that today's high-flying, headline-grabbing companies are not. It respects technology but doesn't consider it central to strategy. It values growth but prefers it controlled. It seeks talented professionals but wants only those who are modest in word and deed. Nestle CEO Peter Brabeck is skeptical of the relentless push for radical transformation heard from every quarter. He believes, instead, in continuous improvement through slow and steady change. Big, dramatic change is fine for a crisis, Brabeck says, but not every company is in crisis all the time. Many companies are like Nestle--performing well, growing and innovating, without frenzy, without bloodshed. While he acknowledges that every company must change in order to compete in today's turbulent marketplace, Brabeck makes the focus of his work identifying and strengthening those aspects of Nestle that should stay the same. For example, Nestle eschews the noise and energy swirling around technology. Many companies make technology the focal point of strategy, Brabeck says, but Nestle is about people, products, and brands. The company uses technology to create better products but keeps it in its right place--the background. Brabeck also talks candidly about how to fight complacency in a successful company, how to institutionalize collaboration in a decentralized organization, and how to resist pressure from analysts and money managers and focus on long-term, sustainable and profitable growth--in short, how to win the war without the revolution. PMID:11213685

  18. FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1

    PubMed Central

    Khan, Shahid Y.; Vasanth, Shivakumar; Kabir, Firoz; Gottsch, John D.; Khan, Arif O.; Chaerkady, Raghothama; Lee, Mei-Chong W.; Leitch, Carmen C.; Ma, Zhiwei; Laux, Julie; Villasmil, Rafael; Khan, Shaheen N.; Riazuddin, Sheikh; Akram, Javed; Cole, Robert N.; Talbot, C. Conover; Pourmand, Nader; Zaghloul, Norann A.; Hejtmancik, J. Fielding; Riazuddin, S. Amer

    2016-01-01

    FOXE3 is a lens-specific transcription factor that has been associated with anterior segment ocular dysgenesis. To determine the transcriptional target(s) of FOXE3 that are indispensable for the anterior segment development, we examined the transcriptome and the proteome of cells expressing truncated FOXE3 responsible for Peters anomaly identified through linkage-coupled next-generation whole-exome sequencing. We found that DNAJB1, an autophagy-associated protein, was the only candidate exhibiting differential expression in both screens. We confirmed the candidacy of DNAJB1 through chromatin immunoprecipitation and luciferase assays while knockdown of DNAJB1 in human lens epithelial cells resulted in a mitotic arrest. Subsequently, we targeted dnajb1a in zebrafish through injection of a splice-blocking morpholino. The dnajb1a morphants exhibited underdeveloped cataractous lenses with persistent apoptotic nuclei. In conclusion, here we report DNAJB1 is a transcriptional target of FOXE3 in a novel pathway that is crucial for the development of the anterior segment of the eye. PMID:27218149

  19. Morphological and karyotypic differentiation in Caranx lugubris (Perciformes: Carangidae) in the St. Peter and St. Paul Archipelago, mid-Atlantic Ridge

    NASA Astrophysics Data System (ADS)

    Jacobina, Uedson Pereira; Martinez, Pablo Ariel; Cioffi, Marcelo de Bello; Garcia, José; Bertollo, Luiz Antonio Carlos; Molina, Wagner Franco

    2014-03-01

    Isolated oceanic islands constitute interesting model systems for the study of colonization processes, as several climatic and oceanographic phenomena have played an important role in the history of the marine ichthyofauna. The present study describes the presence of two morphotypes of Caranx lugubris, in the St. Peter and St. Paul Archipelago located in the mid-Atlantic. Morphotypes were compared in regard to their morphological and cytogenetic patterns, using C-banding, Ag-NORs, staining with CMA3/DAPI fluorochromes and chromosome mapping by dual-color FISH analysis with 5S rDNA and 18S rDNA probes. We found differences in chromosome patterns and marked divergence in body patterns which suggest that different populations of the Atlantic or other provinces can be found in the Archipelago of St. Peter and St. Paul.

  20. Eos Interviews Robert Van Hook, Former AGU Interim Executive Director

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2010-08-01

    Robert Van Hook, who served as AGU's interim executive director since January 2009, led the organization during a transition period that began with the retirement of long-serving executive director A. F. (“Fred”) Spilhaus Jr. Van Hook's tenure concluded on 30 August when Christine McEntee assumed her position as AGU's new executive director (see Eos, 91(17), 153, 156, 2010). During his tenure at AGU, which overlapped with a global economic recession, Van Hook helped to guide the organization through key structural governance changes, strategic planning, and upgrades in technology, human resources, and accounting. He also helped to revitalize public outreach and member services, among many other efforts. Van Hook, president of Transition Management Consulting, recently reflected upon his tenure, the transition period, and the future of AGU. Van Hook credits AGU's strong volunteer leadership—including past presidents Tim Killeen and Tim Grove, current president Mike McPhaden, and president-elect Carol Finn—for courage in moving the organization through a successful transition. “They were the ones who shoved the boat off from the shore. I was lucky enough to be invited into the boat,” he said. He also credits the staff for their resiliency and commitment to supporting AGU's science.

  1. Van der Waals interaction in uniaxial anisotropic media

    NASA Astrophysics Data System (ADS)

    Kornilovitch, Pavel E.

    2013-01-01

    Van der Waals interactions between flat surfaces in uniaxial anisotropic media are investigated in the nonretarded limit. The main focus is the effect of nonzero tilt between the optical axis and the surface normal on the strength of the van der Waals attraction. General expressions for the van der Waals free energy are derived using the surface mode method and the transfer-matrix formalism. To facilitate numerical calculations a temperature-dependent three-band parameterization of the dielectric tensor of the liquid crystal 5CB is developed. A solid slab immersed in a liquid crystal experiences a van der Waals torque that aligns the surface normal relative to the optical axis of the medium. The preferred orientation is different for different materials. Two solid slabs in close proximity experience a van der Waals attraction that is strongest for homeotropic alignment of the intervening liquid crystal for all the materials studied. The results have implications for the stability of plate-like colloids in liquid crystal hosts.

  2. Van der Waals interaction in uniaxial anisotropic media.

    PubMed

    Kornilovitch, Pavel E

    2013-01-23

    Van der Waals interactions between flat surfaces in uniaxial anisotropic media are investigated in the nonretarded limit. The main focus is the effect of nonzero tilt between the optical axis and the surface normal on the strength of the van der Waals attraction. General expressions for the van der Waals free energy are derived using the surface mode method and the transfer-matrix formalism. To facilitate numerical calculations a temperature-dependent three-band parameterization of the dielectric tensor of the liquid crystal 5CB is developed. A solid slab immersed in a liquid crystal experiences a van der Waals torque that aligns the surface normal relative to the optical axis of the medium. The preferred orientation is different for different materials. Two solid slabs in close proximity experience a van der Waals attraction that is strongest for homeotropic alignment of the intervening liquid crystal for all the materials studied. The results have implications for the stability of plate-like colloids in liquid crystal hosts. PMID:23234868

  3. The results of monitoring of hazardous natural processes in the coastal shelf zone of the gulf of Peter the Great in 2012-2013

    NASA Astrophysics Data System (ADS)

    Anokhin, Vladimir; Shcherbakov, Victor; Motychko, Victor; Sokolov, Georgy; Kotov, Sergey; Kartashov, Alexander; Anokhina (1)(2), Zoya

    2014-05-01

    The monitoring of hazardous natural processes In coastal and shelf zone of the gulf of Peter the Great (sea of Japan) in 2012-2013 was made by staff of the Gramberg Institute VNIIOKEANGEOLOGIA . The complex of field researches are: - laser scanning beaches (tachometer Leica HDS 3000); - echosounding underwater coastal slope (sounder-Navigator LCX-37C); - high-frequency acoustic profiling (GeoPulse Subbotom Profilier); - hydromagnetic shooting magnetometer SeaSPY Marine Magnetics; - sonar shooting (complex GEO-CM-MAX); - research of the water column (sounding and sampling); - bottom sampling, including gasgeochemical shooting. The result of this work is the following conclusions: 1. As the shore, and the underwater slope of the district are experiencing the preemptive destruction, the areas of which are quantitative and spatially prevail over the stable and accumulate zones (except the shores of the inland parts of bays and gulfs). 2. The rate of destruction of coast in the Gulf of Peter the Great is 1-20 meters for 100 years, that could pose a serious danger to the population and infrastructure. 3. Number of gasgeochemical anomalies on the shelf of the Gulf of Peter the Great spatially associated with fault lines, limiting blocks of the earth's crust within shelf. 4. Perhaps it is these faults are of the greatest seismic hazard in the moment. 5. Danger of themselves gas emissions The following significant hazards and risks to the region have been studied: seismic and tsunami destruction of shore, gas emissions, technogenic pollution.

  4. Importance of Native Grassland Habitat for Den-Site Selection of Indian Foxes in a Fragmented Landscape

    PubMed Central

    Punjabi, Girish Arjun; Chellam, Ravi; Vanak, Abi Tamim

    2013-01-01

    Fragmentation of native habitats is now a ubiquitous phenomenon affecting wildlife at various scales. We examined selection of den-sites (n = 26) by Indian foxes (Vulpes bengalensis) in a highly modified short-grassland landscape in central India (Jan-May, 2010). At the scale of the home-range, defined by an 800 m circular buffer around den sites, we examined the effect of land-cover edges and roads on selection of sites for denning using a distance-based approach. At the smaller den-area scale, defined by a 25 m x 25 m plot around den and paired available sites, the effect of microhabitat characteristics was examined using discrete-choice models. Indian foxes selected den-sites closer to native grasslands (t = -9.57, P < 0.001) and roads (t = -2.04, P = 0.05) than random at the home-range scale. At the smaller scale, abundance of rodents and higher visibility increased the odds of selection of a site by eight and four times respectively, indicating resource availability and predator avoidance to be important considerations for foxes. Indian foxes largely chose to den in human-made structures, indicated by the proportion of dens found in earthen bunds (0.69) and boulder piles (0.27) in the study area. With agricultural expansion and human modification threatening native short-grassland habitats, their conservation and effective management in human-dominated landscapes will benefit the Indian fox. The presence of some human-made structures within native grasslands would also be beneficial for this den-dependent species. We suggest future studies examine the impact of fragmentation and connectivity of grasslands on survival and reproductive success of the Indian fox. PMID:24098494

  5. Combined endodontic and surgical management of a mandibular lateral incisor with a rare type of dens invaginatus.

    PubMed

    Chaniotis, Antonios M; Tzanetakis, Giorgos N; Kontakiotis, Evangelos G; Tosios, Konstantinos I

    2008-10-01

    Dens invaginatus is a developmental malformation of teeth that most commonly affects permanent maxillary lateral incisors. Presence of dens invaginatus in mandibular permanent teeth is relatively rare. The purpose of this report is to describe the combined nonsurgical and surgical management of a mandibular lateral incisor associated with a rare type of dens invaginatus. Pulp involvement of the malformed tooth, periapical abscess, and severe periodontal destruction were observed. The signs (sinus tracts) and symptoms ceased after completion of the treatment. Satisfactory healing of the periradicular lesion was observed at the 6-month and 2-year follow-up examinations. PMID:18793933

  6. Expression of the denV gene of coliphage T4 in UV-sensitive rad mutants of Saccharomyces cerevisiae

    SciTech Connect

    Valerie, K.; Fronko, G.; Henderson, E.E.; de Riel, J.K.

    1986-10-01

    A plasmid containing the denV gene from bacteriophage T4, under the control of the yeast alcohol dehydrogenase I (ADC1) promoter, conferred a substantial increase in UV resistance in the UV-sensitive Saccharomyces cerevisiae mutants rad1-2 and rad3-2. The UV resistance of the denV+ yeast cells was cell cycle dependent and correlated well with the level of the denV gene product as measured by immunoblotting and by a photoreversal assay for pyrimidine dimer-DNA glycosylase activity.

  7. HyDEn: A Hybrid Steganocryptographic Approach for Data Encryption Using Randomized Error-Correcting DNA Codes

    PubMed Central

    Regoui, Chaouki; Durand, Guillaume; Belliveau, Luc; Léger, Serge

    2013-01-01

    This paper presents a novel hybrid DNA encryption (HyDEn) approach that uses randomized assignments of unique error-correcting DNA Hamming code words for single characters in the extended ASCII set. HyDEn relies on custom-built quaternary codes and a private key used in the randomized assignment of code words and the cyclic permutations applied on the encoded message. Along with its ability to detect and correct errors, HyDEn equals or outperforms existing cryptographic methods and represents a promising in silico DNA steganographic approach. PMID:23984392

  8. HyDEn: a hybrid steganocryptographic approach for data encryption using randomized error-correcting DNA codes.

    PubMed

    Tulpan, Dan; Regoui, Chaouki; Durand, Guillaume; Belliveau, Luc; Léger, Serge

    2013-01-01

    This paper presents a novel hybrid DNA encryption (HyDEn) approach that uses randomized assignments of unique error-correcting DNA Hamming code words for single characters in the extended ASCII set. HyDEn relies on custom-built quaternary codes and a private key used in the randomized assignment of code words and the cyclic permutations applied on the encoded message. Along with its ability to detect and correct errors, HyDEn equals or outperforms existing cryptographic methods and represents a promising in silico DNA steganographic approach. PMID:23984392

  9. van der Waals interactions between excited atoms in generic environments

    NASA Astrophysics Data System (ADS)

    Barcellona, Pablo; Passante, Roberto; Rizzuto, Lucia; Buhmann, Stefan Yoshi

    2016-07-01

    We consider the van der Waals force involving excited atoms in general environments, constituted by magnetodielectric bodies. We develop a dynamical approach studying the dynamics of the atoms and the field, mutually coupled. When only one atom is excited, our dynamical theory suggests that for large distances the van der Waals force acting on the ground-state atom is monotonic, while the force acting in the excited atom is spatially oscillating. We show how this latter force can be related to the known oscillating Casimir-Polder force on an excited atom near a (ground-state) body. Our force also reveals a population-induced dynamics: for times much larger that the atomic lifetime the atoms will decay to their ground states leading to the van der Waals interaction between ground-state atoms.

  10. Spontaneous stacking faults in van der Waals heterostructures

    NASA Astrophysics Data System (ADS)

    Boussinot, G.

    2016-08-01

    The rapid developments in the manipulation of two-dimensional monoatomic layers such as graphene or h-BN allow one to create heterostructures consisting of possibly many chemically different layers, stacked owing to van der Waals attraction. We propose a Frenkel-Kontorova model including a transverse degree of freedom in order to describe local deformations in these heterostructures. We study the case where two dissimilar monolayers are alternatively stacked, and find that stacking faults may emerge spontaneously for a large enough number of stacked layers as a result of the competition between adhesion and elastic energies. This symmetry-breaking transition should become of fundamental importance for the description of three-dimensional van der Waals heterostructures as soon as a precise control on the lattice orientation of the van der Waals layers is achieved.

  11. Van der Waals stacked 2D layered materials for optoelectronics

    NASA Astrophysics Data System (ADS)

    Zhang, Wenjing; Wang, Qixing; Chen, Yu; Wang, Zhuo; Wee, Andrew T. S.

    2016-06-01

    The band gaps of many atomically thin 2D layered materials such as graphene, black phosphorus, monolayer semiconducting transition metal dichalcogenides and hBN range from 0 to 6 eV. These isolated atomic planes can be reassembled into hybrid heterostructures made layer by layer in a precisely chosen sequence. Thus, the electronic properties of 2D materials can be engineered by van der Waals stacking, and the interlayer coupling can be tuned, which opens up avenues for creating new material systems with rich functionalities and novel physical properties. Early studies suggest that van der Waals stacked 2D materials work exceptionally well, dramatically enriching the optoelectronics applications of 2D materials. Here we review recent progress in van der Waals stacked 2D materials, and discuss their potential applications in optoelectronics.

  12. Van der Woude Syndrome with Short Review of the Literature

    PubMed Central

    Deshmukh, Pallavi K.; Deshmukh, Kiran; Mangalgi, Anand; Patil, Subhash; Hugar, Deepa; Kodangal, Saraswathi Fakirappa

    2014-01-01

    Van der Woude syndrome (VWS) is a rare autosomal dominant condition with high penetrance and variable expression. Clinical manifestation of this autosomal dominant clefting syndrome includes bilateral midline lower lip pits, cleft lip, and cleft palate along with hypodontia. These congenital lip pits appear as a malformation in the vermilion border of the lip, with or without excretion. Discomfort caused by spontaneous or induced drainage of saliva/mucus when pressure is applied or during a meal as well as poor aesthetic match is one of the main complaints of patients with congenital lip fistula. The pits are treated by surgical resection. Dentists should be aware of the congenital lip pits as in Van der Woude syndrome because they have been reported to be associated with a variety of malformations or other congenital disorders. Here, the authors report a rare case of Van der Woude syndrome with short review of the literature. PMID:25050184

  13. Collisional stabilization of van der Waals states of ozone

    NASA Astrophysics Data System (ADS)

    Ivanov, Mikhail V.; Babikov, Dmitri

    2011-05-01

    The mixed quantum-classical theory developed earlier [M. Ivanov and D. Babikov, J. Chem. Phys. 134, 144107 (2011)] is employed to treat the collisional energy transfer and the ro-vibrational energy flow in a recombination reaction that forms ozone. Assumption is that the van der Waals states of ozone are formed in the O + O2 collisions, and then stabilized into the states of covalent well by collisions with bath gas. Cross sections for collision induced dissociation of van der Waals states of ozone, for their stabilization into the covalent well, and for their survival in the van der Waals well are computed. The role these states may play in the kinetics of ozone formation is discussed.

  14. Obituary: Thomas C. Van Flandern (1940-2009)

    NASA Astrophysics Data System (ADS)

    Dunham, David; Slabinski, Victor

    2011-12-01

    Dr. Thomas Charles Van Flandern, an expert in celestial mechanics and cosmology, died January 9, 2009 in Seattle, Washington, of colon cancer. He was 68. Van Flandern was an astronomer at the U.S. Naval Observatory from 1963 to 1983. He developed software to predict and analyze lunar occultations to improve lunar orbital and fundamental star catalog data. In later years he championed increasingly controversial theories. But his 1978 prediction that some asteroids have natural satellites, which was almost universally rejected, was verified when the Galileo spacecraft photographed Dactyl, a satellite of (243) Ida, during its flyby in 1993. Besides astronomy and computers, he had strong interests in biochemistry and nutrition, and he ran a business selling personal computers in the 1980s. Tom Van Flandern was born June 26, 1940 in Cleveland, Ohio, the first child of Robert F. Van Flandern and Anna Mary Haley. His father, a police officer, left the family when Tom Van Flandern was 5. His mother died when he was 16; he and his siblings then lived with their grandmother, Margery Jobe, until he went to college. Tom Van Flandern became interested in astronomy as a child. He used his first telescope, purchased with newspaper delivery earnings, to observe lunar occultations, and then learned how to predict them, sparking a life-long passion for dynamical astronomy. While attending St. Ignatius High School, Van Flandern and fellow student Thomas Petrie organized the Cleveland Moonwatch team to observe the first artificial satellites, the only team without an adult organizer. In 1958, Tom Van Flandern entered Xavier University where he led the Cincinnati Moonwatch team. He learned computer programming at a summer job with General Electric and wrote software to calculate "look angles" from orbital elements. The Cincinnati team became a top producer of observations using these predictions. Tom obtained a B.S. in mathematics from Xavier in 1962. He spent the next year at

  15. CheckDen, a program to compute quantum molecular properties on spatial grids.

    PubMed

    Pacios, Luis F; Fernandez, Alberto

    2009-09-01

    CheckDen, a program to compute quantum molecular properties on a variety of spatial grids is presented. The program reads as unique input wavefunction files written by standard quantum packages and calculates the electron density rho(r), promolecule and density difference function, gradient of rho(r), Laplacian of rho(r), information entropy, electrostatic potential, kinetic energy densities G(r) and K(r), electron localization function (ELF), and localized orbital locator (LOL) function. These properties can be calculated on a wide range of one-, two-, and three-dimensional grids that can be processed by widely used graphics programs to render high-resolution images. CheckDen offers also other options as extracting separate atom contributions to the property computed, converting grid output data into CUBE and OpenDX volumetric data formats, and perform arithmetic combinations with grid files in all the recognized formats. PMID:19447056

  16. The Economics of van der Waals Force Engineering

    NASA Astrophysics Data System (ADS)

    Pinto, Fabrizio

    2008-01-01

    As micro-electro-mechanical system (MEMS) fabrication continues on an ever-decreasing scale, new technological challenges must be successfully negotiated if Moore's Law is to be an even approximately valid model of the future of device miniaturization. Among the most significant obstacles is the existence of strong surface forces related to quantum mechanical van der Waals interatomic interactions, which rapidly diverge as the distance between any two neutral boundaries decreases. The van der Waals force is a contributing factor in several device failures and limitations, including, for instance, stiction and oscillator non-linearities. In the last decade, however, it has been conclusively shown that van der Waals forces are not just a MEMS limitation but can be engineered in both magnitude and sign so as to enable classes of proprietary inventions which either deliver novel capabilities or improve upon existing ones. The evolution of van der Waals force research from an almost exclusively theoretical field in quantum-electro-dynamics to an enabling nanotechnology discipline represents a useful example of the ongoing paradigm shift from government-centered to private-capital funded R&D in cutting-edge physics leading to potentially profitable products. In this paper, we discuss the reasons van der Waals force engineering may lead to the creation of thriving markets both in the short and medium terms by highlighting technical challenges that can be competitively addressed by this novel approach. We also discuss some notable obstacles to the cultural transformation of the academic research community required for the emergence of a functional van der Waals force engineering industry worldwide.

  17. Excision repair characteristics of denV-transformed xeroderma pigmentosum cells.

    PubMed

    Ley, R D; Applegate, L A; de Riel, J K; Henderson, E E

    1989-03-01

    Introduction of the denV gene of phage T4, encoding the pyrimidine dimer-specific endonuclease V, into xeroderma pigmentosum cells XP12RO(M1) was reported to result in partial restoration of colony-forming ability and excision repair synthesis. We have further characterized 3 denV-transformed XP clones in terms of rates of excision of pyrimidine dimers and size of the resulting resynthesized regions following exposure to 100 J/m2 from an FS-40 sunlamp. In the denV-transformed XP cells we observed 50% dimer removal within 3-6 h after UV exposure as compared to no measurable removal in the XP12RO(M1) line and 50% dimer excision after 18 h in the GM637A human, control cells. Dimer removal was assayed with Micrococcus luteus UV-endonuclease in conjunction with sedimentation of treated DNA in alkaline sucrose gradients. The size of the resulting repaired regions was determined by the bromouracil photolysis technique. Based on the photolytic sensitivity of DNA repaired in the presence of bromodeoxyuridine, we calculated that the excision of a dimer in the GM637A cells appears to be accompanied by the resynthesis of a region approximately 95 nucleotides in length. Conversely, the resynthesized regions in the denV-transformed clones were considerably smaller and were estimated to be between 13 and 18 nucleotides in length. These results may indicate that either the endonuclease that initiated dimer repair dictated the size of the resynthesized region or that the long-patch repair observed in the normal cells resulted from the repair of non-dimer DNA lesions. PMID:2918865

  18. Case study of total energy system, Sher-Den Mall, Sherman, Texas

    SciTech Connect

    Myrtetus, G.B.; Levey, M.D.

    1980-12-01

    The Sher-Den Mall shopping center receives all of its electricity and heating and cooling energy from a total energy plant located within the shopping center proper. Four engine-generator units are fueled primarily by natural gas, with some fuel oil use. The following are presented: initial corporate planning, investigation, and feasibility studies; a description of the total energy system; capital costs; plant operations, and revenue structure. Tables, figures, exhibits, and equipment specification lists are presented. (MHR)

  19. Technische Systeme für den Herzersatz und die Herzunterstützung

    NASA Astrophysics Data System (ADS)

    Schöb, Reto; Loree, Howard M.

    Herzkrankheiten verursachen allein in den Vereinigten Staaten jährlich mehr als 700’000 Todesfälle. Ungefähr 3 Millionen Patienten in den U.S.A. leiden gemäss der American Heart Association (AHA) und dem National Heart, Lung and Blood Institute (NHLBI) an kongestivem Herzversagen (Congestive Heart Failure, CHF), welches eine chronische, sehr entkräftende und degenerative Krankheit ist: Das Herz ist dabei unfähig, hinreichend Blut zu den Organen des Körpers zu pumpen. Über 400’000 Fälle von CHF werden jedes Jahr diagnostiziert. Ähnliche Zahlen werden für Europa und Japan zusammen geschätzt. Basierend auf Daten vom AHA und NHLBI beträgt die fünfjährige Überlebensrate für CHF-Patienten lediglich etwa 50% [1]. 70’000-120’000 dieser Patienten könnten von einer Herzverpflanzung profitieren. 1999 wurden in den USA aber nur 2185 Herztransplantationen durchgeführt während die Warteliste über 4000 Patienten beträgt [2]. Ein akuter Mangel an Spenderherzen und die enormen Kosten (250’000-400’000 USD pro Patient) sind die begrenzenden Faktoren für Herztransplantationen [3]. Dies bedeutet, dass eine riesige Anzahl von Patienten durch ein zuverlässiges und verschleissfreies, nichtthrombotisches, total implantierbares, künstliches Herz gerettet werden könnten. Bis heute jedoch kein derartiges Implantat kommerziell verfügbar.

  20. In Vivo Characterization of the Activation and Interaction of the VanR-VanS Two-Component Regulatory System Controlling Glycopeptide Antibiotic Resistance in Two Related Streptomyces Species

    PubMed Central

    Novotna, Gabriela Balikova; Kwun, Min Jung

    2015-01-01

    The VanR-VanS two-component system is responsible for inducing resistance to glycopeptide antibiotics in various bacteria. We have performed a comparative study of the VanR-VanS systems from two streptomyces strains, Streptomyces coelicolor and Streptomyces toyocaensis, to characterize how the two proteins cooperate to signal the presence of antibiotics and to define the functional nature of each protein in each strain background. The results indicate that the glycopeptide antibiotic inducer specificity is determined solely by the differences between the amino acid sequences of the VanR-VanS two-component systems present in each strain rather than by any inherent differences in general cell properties, including cell wall structure and biosynthesis. VanR of S. coelicolor (VanRsc) functioned with either sensor kinase partner, while VanR of S. toyocaensis (VanRst) functioned only with its cognate partner, S. toyocaensis VanS (VanSst). In contrast to VanRsc, which is known to be capable of phosphorylation by acetylphosphate, VanRst could not be activated in vivo independently of a VanS sensor kinase. A series of amino acid sequence modifications changing residues in the N-terminal receiver (REC) domain of VanRst to the corresponding residues present in VanRsc failed to create a protein capable of being activated by VanS of S. coelicolor (VanSsc), which suggests that interaction of the response regulator with its cognate sensor kinase may require a region more extended than the REC domain. A T69S amino acid substitution in the REC domain of VanRst produced a strain exhibiting weak constitutive resistance, indicating that this particular amino acid may play a key role for VanS-independent phosphorylation in the response regulator protein. PMID:26711760

  1. [Van Neck-Odelberg disease. Report of two cases].

    PubMed

    Nagy, Örs; Zuh, Sándor-György; Kovács, Attila; Sólyom, Árpád; Sólyom, Réka; Gergely, István

    2016-05-22

    Osteochondritis ischiopubica or van Neck-Odelberg disease is characterized by atypical ossification of the ischiopubic synchondrosis. Clinical symptoms are usually pain, limping and limited range of motion of the hip joint. Radiologic images may be confused with the possibility of fracture, tumor or inflammation. In some cases it may be difficult to set up the accurate diagnosis, and during the diagnostic process it is essential that van Neck-Odelberg disease should be considered. In this paper the authors draw attention to this rare disorder and they present the history of two patients who posed diagnostic difficulties. PMID:27177791

  2. Van vleck paramagnetism in orthorhombic TiO2 (Brookite)

    USGS Publications Warehouse

    Senftle, F.E.; Thorpe, A.N.

    1968-01-01

    The magnetic susceptibility of the orthorhombic form of titanium dioxide has been measured from 5 to 300??K. After deducting the temperature-dependent component, which is probably due to defects or impurities, and the free-ion diamagnetic component, the Van Vleck paramagnetism was estimated to be 33??10-6 emu/mole. Comparison is made between this value and the Van Vleck paramagnetism of strontium titanate and the two tetragonal forms of titanium dioxide: rutile and anatase. ?? 1968 The American Physical Society.

  3. NOAA's Van-Based Mobile Atmospheric Emissions Measurement Laboratory

    NASA Astrophysics Data System (ADS)

    Dube, W. P.; Peischl, J.; Neuman, J. A.; Eilerman, S. J.; Holloway, M.; Roberts, O.; Aikin, K. C.; Ryerson, T. B.

    2015-12-01

    The Chemical Science Division (CSD) mobile atmospheric emissions measurement laboratory is the second and latest of two mobile measurement vans outfitted for atmospheric sampling by the NOAA Earth System Research Laboratory. In this presentation we will describe the modifications made to this vehicle to provide a versatile and relatively inexpensive instrument platform including: the 2 kW 120 volt instrument power system; battery back-up system; data acquisition system; real-time display; meteorological, directional, and position sensor package; and the typical atmospheric emissions instrument package. The van conversion uses commercially available, off-the-shelf components from the marine and RV industries, thus keeping the costs quite modest.

  4. Curves of growth for van der Waals broadened spectral lines

    NASA Technical Reports Server (NTRS)

    Park, C.

    1980-01-01

    Curves of growth are evaluated for a spectral line broadened by the van der Waals interactions during collisions. The growth of the equivalent widths of such lines is shown to be dependent on the product of the perturber density and the 6/10 power of the van der Waals potential coefficient. When the parameter is small, the widths grow as the 1/2 power of the optical depth as they do for the Voigt profile: but when the parameter is large, they grow as 2/3 power and, hence, faster than the Voigt profile. An approximate analytical expression for the computed growth characteristics is given.

  5. Baseline tests of the Volkswagen transporter electric delivery van

    NASA Technical Reports Server (NTRS)

    Soltis, R. F.; Mcbrien, E. F.; Bozek, J. M.; Gourash, F.

    1978-01-01

    The Volkswagen Transporter, an electric delivery van, was tested as part of an Energy Research and Development Administration (ERDA) project to characterize the state of the art of electric vehicles. The Volkswagen Transporter is a standard Volkswagen van that has been converted to an electric vehicle. It is powered by a 144-volt traction battery. A direct current (dc) chopper controller, actuated by a conventional accelerator pedal, regulates the voltage or power applied to the 16-kilowatt (21-hp) motor. The braking system uses conventional hydraulic braking in combination with an electric regenerative braking system. The Volkswagen vehicle performance test results are presented.

  6. Notes on Van der Meer scan for absolute luminosity measurement

    NASA Astrophysics Data System (ADS)

    Balagura, Vladislav

    2011-10-01

    The absolute luminosity can be measured in an accelerator by sweeping beams transversely across each other in the so-called van der Meer scan. We prove that the method can be applied in the general case of arbitrary beam directions and a separation scan plane. A simple method to develop an image of the beam in its transverse plane from spatial distributions of interaction vertexes is also proposed. From the beam images one can determine their overlap and the absolute luminosity. This provides an alternative way of the luminosity measurement during van der Meer scan.

  7. Thermal effects on van der Waals adhesive forces

    NASA Astrophysics Data System (ADS)

    Pinon, A. V.; Wierez-Kien, M.; Craciun, A. D.; Beyer, N.; Gallani, J. L.; Rastei, M. V.

    2016-01-01

    We present an experimental and theoretical study on how thermal energy alters van der Waals adhesion forces in nanoscale contacts stretched by mechanical probes. The force follows a distribution whose density function is an asymmetric bell-shaped curve presenting a temperature-dependent negative skewness. With increasing temperature the asymmetry increases whereas the most probable force value decreases. Using a 2-8 Lennard-Jones interaction potential within the reaction rate theory, we offer a theoretical framework permitting an evaluation of the microscopic parameters governing adhesion in a van der Waals nanocontact subjected to mechanical fluctuations.

  8. Photonic analog of a van Hove singularity in metamaterials

    NASA Astrophysics Data System (ADS)

    Cortes, Cristian L.; Jacob, Zubin

    2013-07-01

    We introduce the photonic analog of electronic van Hove singularities (VHS) in artificial media (metamaterials) with hyperbolic dispersion. Unlike photonic and electronic crystals, the VHS in metamaterials are unrelated to the underlying periodicity and occur due to slow-light modes in the structure. We show that the VHS characteristics are manifested in the near-field local density of optical states in spite of the losses, dispersion, and finite unit-cell size of the hyperbolic metamaterial. Finally, we show that this work should lead to quantum, thermal, nanolasing, and biosensing applications of van Hove singularities in hyperbolic metamaterials achievable by current fabrication technology.

  9. Twelve-Month Evaluation of UPS Diesel Hybrid Electric Delivery Vans

    SciTech Connect

    Lammert, M.

    2009-12-01

    Results of an NREL study of a parallel hybrid electric-diesel propulsion system in United Parcel Service-operated delivery vans show that the hybrids had higher fuel economy than standard diesel vans.

  10. 77 FR 28924 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel VAN'S CATCH TWO; Invitation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Maritime Administration Requested Administrative Waiver of the Coastwise Trade Laws: Vessel VAN'S CATCH TWO... the vessel VAN'S CATCH TWO is: Intended Commercial Use of Vessel: ``Sport Fishing...

  11. Conversion of Chemical Reaction Energy into Useful Work in the Van't Hoff Equilibrium Box

    ERIC Educational Resources Information Center

    Bazhin, N. M.; Parmon, V. N.

    2007-01-01

    The ideal van't Hoff equilibrium box is described in detail. It shows that van't Hoff equilibrium box divided in two parts can simultaneously produce heat and useful work without violation of the first law of thermodynamics.

  12. [Failed compression osteosynthesis of the dens axis treated by anterior C1-C2 transarticular stabilisation. Case report].

    PubMed

    Kočiš, J; Kelbl, M

    2011-01-01

    We describe the case of an 80-year-old female patient who had undergone anterior C1-C2 transarticular stabilisation and was subsequently treated by the triple-screw method for failed compression osteosynthesis of a AO type III dens axis fracture. Key words: dens axis, upper cervical spine fracture, eldery, triple screw technique, anterior transarticular C1-C2 stabilisation. PMID:21729645

  13. VanA and VanB Positive Vancomycin-resistant Staphylococcus aureus Among Clinical Isolates in Shiraz, South of Iran

    PubMed Central

    Saadat, Sareh; Solhjoo, Kavous; Norooz-Nejad, Mohammad-Javad; Kazemi, Akbar

    2014-01-01

    Objective The purpose of this study was to determine the prevalence of vancomycin-resistant Staphylococcus aureus isolated from clinical samples in Shiraz hospitals. Methods From March to December 2012, 100 S. aureus isolates (mainly from wound and blood) were collected from three hospitals in Shiraz, south of Iran. After identification of Staphylococcus aureus by biochemical, microbiological and molecular methods, antibiotic susceptibility testing was performed by Kirby-Bauer disc diffusion test for 13 different antibiotics. Vancomycin-resistant Staphylococcus aureus isolates were determined by vancomycin agar screening test and PCR for vancomycin resistant genes (vanA and vanB). Results The lowest and highest resistance was seen for quinupristin-dalfopristin (n=1) and ampicillin (n=95), respectively. Vancomycin agar screening test showed that 37 isolates can grow on these media. Further study by PCR also detected vanA and/or vanB genes in all of these strains. Also, 19 isolates showed either vanA or vanB but were susceptible according to vancomycin agar screening test. In total, vanA and vanB resistant genes were detected in 34% and 37% of clinical isolates, respectively. Conclusion The results showed that the frequency of vancomycin resistance genes (vanA, vanB) is very high in Staphylococcus aureus strains isolated from patients in south of Iran. Thus, urgent interventions are needed to keep the emergence and transmission of these isolates to a minimum. PMID:25337309

  14. Genetic Analysis of a Chromosomal Region Containing vanA and vanB, Genes Required for Conversion of Either Ferulate or Vanillate to Protocatechuate in Acinetobacter†

    PubMed Central

    Segura, Ana; Bünz, Patricia V.; D’Argenio, David A.; Ornston, L. Nicholas

    1999-01-01

    VanA and VanB form an oxygenative demethylase that converts vanillate to protocatechuate in microorganisms. Ferulate, an abundant phytochemical, had been shown to be metabolized through a vanillate intermediate in several Pseudomonas isolates, and biochemical evidence had indicated that vanillate also is an intermediate in ferulate catabolism by Acinetobacter. Genetic evidence supporting this conclusion was obtained by characterization of mutant Acinetobacter strains blocked in catabolism of both ferulate and vanillate. Cloned Acinetobacter vanA and vanB were shown to be members of a chromosomal segment remote from a supraoperonic cluster containing other genes required for completion of the catabolism of ferulate and its structural analogs, caffeate and coumarate, through protocatechuate. The nucleotide sequence of DNA containing vanA and vanB demonstrated the presence of genes that, on the basis of nucleotide sequence similarity, appeared to be associated with transport of aromatic compounds, metabolism of such compounds, or iron scavenging. Spontaneous deletion of 100 kb of DNA containing this segment does not impede the growth of cells with simple carbon sources other than vanillate or ferulate. Additional spontaneous mutations blocking vanA and vanB expression were shown to be mediated by IS1236, including insertion of the newly discovered composite transposon Tn5613. On the whole, vanA and vanB appear to be located within a nonessential genetic region that exhibits considerable genetic malleability in Acinetobacter. The overall organization of genes neighboring Acinetobacter vanA and vanB, including a putative transcriptional regulatory gene that is convergently transcribed and overlaps vanB, is conserved in Pseudomonas aeruginosa but has undergone radical rearrangement in other Pseudomonas species. PMID:10348863

  15. Catalogue of polar bear (Ursus maritimus) maternal den locations in the Beaufort Sea and neighboring regions, Alaska, 1910-2010

    USGS Publications Warehouse

    Durner, George M.; Fischbach, Anthony S.; Amstrup, Steven C.; Douglas, David C.

    2010-01-01

    This report presents data on the approximate locations and methods of discovery of 392 polar bear (Ursus maritimus) maternal dens found in the Beaufort Sea and neighboring regions between 1910 and 2010 that are archived by the U.S. Geological Survey, Alaska Science Center, Anchorage, Alaska. A description of data collection methods, biases associated with collection method, primary time periods, and spatial resolution are provided. Polar bears in the Beaufort Sea and nearby regions den on both the sea ice and on land. Standardized VHF surveys and satellite radio telemetry data provide a general understanding of where polar bears have denned in this region over the past 3 decades. Den observations made during other research activities and anecdotal reports from other government agencies, coastal residents, and industry personnel also are reported. Data on past polar bear maternal den locations are provided to inform the public and to provide information for natural resource agencies in planning activities to avoid or minimize interference with polar bear maternity dens.

  16. Gene vanXYC encodes D,D -dipeptidase (VanX) and D,D-carboxypeptidase (VanY) activities in vancomycin-resistant Enterococcus gallinarum BM4174.

    PubMed

    Reynolds, P E; Arias, C A; Courvalin, P

    1999-10-01

    VanX and VanY have strict D,D-dipeptidase and D,D-carboxypeptidase activity, respectively, that eliminates production of peptidoglycan precursors ending in D-alanyl-D-alanine (D-Ala-D-Ala) in glycopeptide-resistant enterococci in which the C-terminal D-Ala residue has been replaced by D-lactate. Enterococcus gallinarum BM4174 synthesizes peptidoglycan precursors ending in D-Ala-D-serine (D-Ala-D-Ser) essential for VanC-type vancomycin resistance. Insertional inactivation of the vanC-1 gene encoding the ligase that catalyses synthesis of D-Ala-D-Ser has a polar effect on both D, D-dipeptidase and D,D-carboxypeptidase activities. The open reading frame downstream from vanC-1 encoded a soluble protein designated VanXYC (Mr 22 318), which had both of these activities. It had 39% identity and 74% similarity to VanY in an overlap of 158 amino acids, and contained consensus sequences for binding zinc, stabilizing the binding of substrate and catalysing hydrolysis that are present in both VanX- and VanY-type enzymes. It had very low dipeptidase activity against D-Ala-D-Ser, unlike VanX, and no activity against UDP-MurNAc-pentapeptide[D-Ser], unlike VanY. The introduction of plasmid pAT708(vanC-1,XYC) or pAT717(vanXYC) into vancomycin-susceptible Enterococcus faecalis JH2-2 conferred low-level vancomycin resistance only when D-Ser was present in the growth medium. The peptidoglycan precursor profiles of E. faecalis JH2-2 and JH2-2(pAT708) and JH2-2(pAT717) indicated that the function of VanXYC was hydrolysis of D-Ala-D-Ala and removal of D-Ala from UDP-MurNAc-pentapeptide[D-Ala]. VanC-1 and VanXYC were essential, but not sufficient, for vancomycin resistance. PMID:10564477

  17. Honoring the Admiral: Boerhaave-van Wassenaer's syndrome.

    PubMed

    Adams, B D; Sebastian, B M; Carter, J

    2006-01-01

    Dr. Herman Boerhaave (1668-1738) first described esophageal rupture and the subsequent mediastinal sepsis based upon his careful clinical and autopsy findings and hundreds of references have since been written about Boerhaave's syndrome. Several fine historical accounts of this brilliant scientist have been published over the years and he has received appropriate credit for his valuable contributions. But what about that unfortunate propositus that Dr. Boerhaave attended to, performed necropsy upon, and subsequently received acclaim with? Medical history pays inadequate regard to the Baron Jan Gerrit van Wassenaer heer van Rosenberg, Prefect of Rhineland and Grand Admiral of the Dutch Fleet. This figure was a nobleman and war hero at the peak of the Dutch Golden Age who played his role in steering the course of European history. Without this nobleman's heroic contemporaneous account, Boerhaave's celebrated impact on medical science would never have been realized. Therefore, we offer an overdue recitation of Admiral van Wassenaer's biography. Based on found precedent we propose that spontaneous rupture of the esophagus be henceforth referred to as the 'Boerhaave-van Wassenaer's syndrome'. PMID:16722990

  18. 46 CFR 194.10-15 - Magazine van construction.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Magazine van construction. 194.10-15 Section 194.10-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS HANDLING, USE, AND CONTROL OF EXPLOSIVES AND OTHER HAZARDOUS MATERIALS Magazines § 194.10-15 Magazine...

  19. 46 CFR 194.10-15 - Magazine van construction.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Magazine van construction. 194.10-15 Section 194.10-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS HANDLING, USE, AND CONTROL OF EXPLOSIVES AND OTHER HAZARDOUS MATERIALS Magazines § 194.10-15 Magazine...

  20. 46 CFR 194.10-15 - Magazine van construction.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Magazine van construction. 194.10-15 Section 194.10-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS HANDLING, USE, AND CONTROL OF EXPLOSIVES AND OTHER HAZARDOUS MATERIALS Magazines § 194.10-15 Magazine...

  1. 46 CFR 194.10-15 - Magazine van construction.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Magazine van construction. 194.10-15 Section 194.10-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS HANDLING, USE, AND CONTROL OF EXPLOSIVES AND OTHER HAZARDOUS MATERIALS Magazines § 194.10-15 Magazine...

  2. 1. Photocopy of woodengraving by Van Vleck & Keith from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopy of wood-engraving by Van Vleck & Keith from a photograph by Shireff of Higgins' Daguerrian Rooms, Sacramento, with figures, etc. touched up by Nahl & Brothers. Illustration from The Californian Farmer, July 4, 1862. STANFORD HOUSE BY SETH BABSON, VIEW FROM THE NORTHEAST - Leland Stanford House, 800 N Street, Sacramento, Sacramento County, CA

  3. Excited nucleon as a van der Waals system of partons

    SciTech Connect

    Jenkovszky, L. L.; Muskeyev, A. O. Yezhov, S. N.

    2012-06-15

    Saturation in deep inelastic scattering (DIS) and deeply virtual Compton scattering (DVCS) is associated with a phase transition between the partonic gas, typical of moderate x and Q{sup 2}, and partonic fluid appearing at increasing Q{sup 2} and decreasing Bjorken x. We suggest the van der Waals equation of state to describe properly this phase transition.

  4. MTR BASEMENT. WORKERS (DON ALVORD AND CYRIL VAN ORDEN OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    MTR BASEMENT. WORKERS (DON ALVORD AND CYRIL VAN ORDEN OF PHILLIPS PETROLEUM CO.) POSE FOR GAMMA IRRADIATION EXPERIMENT IN MTR CANAL. CANS OF FOOD WILL BE LOWERED TO CANAL BOTTOM, WHERE SPENT MTR FUEL ELEMENTS EMIT GAMMA RADIATION. INL NEGATIVE NO. 11746. Unknown Photographer, 8/20/1954 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  5. Research at the BNL Tandem Van de Graaff Facility, 1980

    SciTech Connect

    Not Available

    1981-03-01

    Research programs at the Brookhaven Van de Graaff accelerators are summarized. Major accomplishments of the laboratory are discussed including quasielastic reactions, high-spin spectroscopy, yrast spectra, fusion reactions, and atomic physics. The outside user program at the Laboratory is discussed. Research proposed for 1981 is outlined. (GHT)

  6. Statistical complexity, virial expansion, and van der Waals equation

    NASA Astrophysics Data System (ADS)

    Pennini, F.; Plastino, A.

    2016-09-01

    We investigate the notion of LMC statistical complexity with regards to a real gas and in terms of the second virial coefficient. The ensuing results are applied to the van der Waals equation. Interestingly enough, one finds a complexity-interpretation for the associated phase transition.

  7. James Van Allen and His Namesake NASA Mission

    NASA Astrophysics Data System (ADS)

    Baker, D. N.; Hoxie, V. C.; Jaynes, A.; Kale, A.; Kanekal, S. G.; Li, X.; Reeves, G. D.; Spence, H. E.

    2013-12-01

    In many ways, James A. Van Allen defined and "invented" modern space research. His example showed the way for government-university partners to pursue basic research that also served important national and international goals. He was a tireless advocate for space exploration and for the role of space science in the spectrum of national priorities.

  8. Van Allen Probes Science Gateway: A Centralized Data Access Point

    NASA Astrophysics Data System (ADS)

    Romeo, G.; Barnes, R. J.; Ukhorskiy, A. Y.; Sotirelis, T.; Stephens, G. K.; Kessel, R.; Potter, M.

    2015-12-01

    The Van Allen Probes Science Gateway acts a centralized interface to the instrument Science Operation Centers (SOCs), provides mission planning tools, and hosts a number of science related activities such as the mission bibliography. Most importantly, the Gateway acts as the primary site for processing and delivering the Van Allen Probes Space Weather data to users. Over the past years, the web-site has been completely redesigned with the focus on easier navigation and improvements of the existing tools such as the orbit plotter, position calculator and magnetic footprint tool. In addition, a new data plotting facility has been added. Based on HTML5, which allows users to interactively plot Van Allen Probes science and space weather data. The user can tailor the tool to display exactly the plot they wish to see and then share this with other users via either a URL or by QR code. Various types of plots can be created, including, simple time series, data plotted as a function of orbital location, and time versus L-Shell, capability of visualizing data from both probes (A & B) on the same plot. In cooperation with all Van Allen Probes Instrument SOCs, the Science Gateway will soon be able to serve higher level data products (Level 3), and to visualize them via the above mentioned HTML5 interface. Users will also be able to create customized CDF files on the fly.

  9. The Evolving Space Weather System—Van Allen Probes Contribution

    NASA Astrophysics Data System (ADS)

    Zanetti, L. J.; Mauk, B. H.; Fox, N. J.; Barnes, R. J.; Weiss, M.; Sotirelis, T. S.; Raouafi, N.-E.; Kessel, R. L.; Becker, H. N.

    2014-10-01

    The overarching goal and purpose of the study of space weather is clear—to understand and address the issues caused by solar disturbances on humans and technological systems. Space weather has evolved in the past few decades from a collection of concerned agencies and researchers to a critical function of the National Weather Service of NOAA. The general effects have also evolved from the well-known telegraph disruptions of the mid-1800s to modern day disturbances of the electric power grid, communications and navigation, human spaceflight and spacecraft systems. The last two items in this list, and specifically the effects of penetrating radiation, were the impetus for the space weather broadcast implemented on NASA's Van Allen Probes' twin pair of satellites, launched in August of 2012 and orbiting directly through Earth's severe radiation belts. The Van Allen Probes mission, formerly the Radiation Belt Storm Probes (RBSP), was renamed soon after launch to honor the discoverer of Earth's radiation belts at the beginning of the space age, the late James Van Allen (the spacecraft themselves are still referred to as RBSP-A and RBSP-B). The Van Allen Probes are one part of NASA's Living With a Star program formulated to advance the scientific understanding of the connection between solar disturbances, the resulting heliospheric conditions, and their effects on the geospace and Earth environment.

  10. 46 CFR 194.10-15 - Magazine van construction.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... system shall be of watertight construction and bear a label plate denoting the power requirement of the..., USE, AND CONTROL OF EXPLOSIVES AND OTHER HAZARDOUS MATERIALS Magazines § 194.10-15 Magazine van... incombustible materials. (b) Lighting fixtures, if installed, shall be of an approved type equipped with...

  11. How Children Learn Geometry: The Van Hiele Theory.

    ERIC Educational Resources Information Center

    Pegg, John

    1985-01-01

    Describes the characteristics of the five levels of thinking in the hierarchical sequence postulated by the van Hiele theory, as well as several properties associated with each level of thinking. Also discusses some implications of the theory for the planning of geometry instruction in the classroom. (JN)

  12. 26. Old Crosscut Canal, Details for Drop Structures at Van ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. Old Crosscut Canal, Details for Drop Structures at Van Buren Street and McDowell Road, Elevation, Plan and Section, February 1975. Source: city of Phoenix Engineering Department. - Old Crosscut Canal, North Side of Salt River, Phoenix, Maricopa County, AZ

  13. 27. Old Crosscut Canal, Details for Drop Structures at Van ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. Old Crosscut Canal, Details for Drop Structures at Van Buren Street and McDowell Road, Wingwall Footing Plan and Pipe Detail, February 1975. Source: City of Phoenix Engineering Department. - Old Crosscut Canal, North Side of Salt River, Phoenix, Maricopa County, AZ

  14. The Evaluation of the Parameters in the van Deemter Equation.

    ERIC Educational Resources Information Center

    Moody, Harvey W.

    1982-01-01

    Describes experiment expanding on principles behind measuring efficiency of chromatographic columns and allowing calculation of parameters in the van Deemter equation. Easily accomplished in a three-hour period using a gas chromatograph in which gas flow can be changed and measured. Mathematical solutions can be attained with programmable…

  15. Charging belt noise in a Van de Graaff accelerator

    SciTech Connect

    Trainor, T.A.

    1988-01-01

    With the aid of a Fast Fourier Transformer (FFT) spectrum analyzer it has been possible to decompose Van de Graaff terminal voltage noise into components that can be related to various properties of the charging belt. One consequence has been the elimination of the fundamental belt frequency component by a novel belt charge transfer device. 18 figs.

  16. 46 CFR 195.11-10 - Design and construction of portable vans.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Design and construction of portable vans. 195.11-10 Section 195.11-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS VESSEL CONTROL AND MISCELLANEOUS SYSTEMS AND EQUIPMENT Portable Vans and Tanks § 195.11-10 Design and construction of portable vans....

  17. Obituary: Leon Van Speybroeck, 1935-2002

    NASA Astrophysics Data System (ADS)

    Gorenstein, Paul; Tananbaum, Harvey Dale

    2003-12-01

    Leon Van Speybroeck, a master designer of X-ray telescope mirrors and the telescope scientist for the Chandra X-ray Observatory, died in Newton, Massachusetts, on 25 December 2002, shortly after learning that he had metastatic melanoma. Leon was born on 27 August 1935 in Wichita, Kansas. His father, Paul, was Assistant Treasurer and head of the accounting department at Beech Aircraft, and his mother, Anna Florence (Utley), was a homemaker. Both parents died in 1996. Leon's younger sister, Saundra, is a nurse and his younger brother, John, is a surgeon. Leon received a BS in 1957 and a PhD in 1965, both in physics, from MIT. His PhD thesis, ``Elastic Electron-Deuteron Scattering at High Momentum Transfer," was carried out under the supervision of Henry Kendall and Jerome Friedman. Leon spent two more years at MIT as a research associate. In 1967, he was hired by American Science and Engineering (AS&E) in Cambridge, Massachusetts, and joined the X-ray astronomy group led by Riccardo Giacconi, who received the 2002 Nobel Prize in Physics for contributions to astrophysics that led to the discovery of cosmic X-ray sources. Leon soon became involved in the design and construction of high-resolution, grazing-incidence X-ray telescopes, starting with the Apollo Telescope Mount flown on NASA's Skylab from 1973 to 1974. A series of high-resolution X-ray images of the solar corona led to dramatic changes in ideas about the solar corona, with new emphasis on magnetic dynamo processes. When the Smithsonian Astrophysical Observatory and the Harvard College Observatory morphed into the Harvard-Smithsonian Center for Astrophysics (CfA) in 1973, Leon, with Giacconi and other senior X-ray astronomers from AS&E, joined the CfA and formed the high-energy astrophysics division. Leon guided the design and development of the X-ray mirrors on NASA's Einstein Observatory, which was flown from 1978 to 1981 as the first cosmic X-ray observatory with an imaging telescope. Along the way, he

  18. Detection of seasonal asymptomatic dermatophytes in Van cats

    PubMed Central

    Ilhan, Ziya; Karaca, Mehmet; Ekin, Ismail Hakki; Solmaz, Hasan; Akkan, Hasan Altan; Tutuncu, Mehmet

    2016-01-01

    The Van cat is a domestic landrace found in the Van province of eastern Turkey. In this study, we aimed to determine the seasonal carriage of dermatophytes in Van cats without clinical lesions. A total of 264 hair specimens were collected from clinically healthy cats in and around the Van Province. Of these samples, 30.3% were obtained in spring, 30.6% in summer, 16.6% in autumn, and 22.3% in winter; 45.1% of samples were from male cats and the rest from female ones. Of the studied cats, 118 were younger than 1 year, 78 were 1–3 years old, and 68 were older than 3 years. The specimens were subjected to direct microscopic examination with 15% potassium hydroxide and cultured on Sabouraud dextrose agar and dermatophyte test medium supplemented with cycloheximide and chloramphenicol. Dermatophyte identification was carried out based on macroscopic and microscopic colony morphology, urease activities, in vitro hair perforation test, growth at 37 °C, and pigmentation on corn meal agar. Dermatophytes were isolated from 19 (7.1%) of the 264 specimens examined. The most frequently isolated fungi were Trichophyton terrestre (4.1%), followed by Microsporum gypseum (1.1%), M. nanum (1.1%), and T. mentagrophytes (0.7%), and these fungi may represent a health risk for humans in contact with clinically healthy Van cats. M. canis was not isolated from any of the specimens. Our results show no significant (p > 0.05) association between carriage of dermatophytes and the gender of cats. The carriage rate of dermatophytes was high in spring and winter, and the only possible risk factor for infection was age of the animal. PMID:26887249

  19. Detection of seasonal asymptomatic dermatophytes in Van cats.

    PubMed

    Ilhan, Ziya; Karaca, Mehmet; Ekin, Ismail Hakki; Solmaz, Hasan; Akkan, Hasan Altan; Tutuncu, Mehmet

    2016-01-01

    The Van cat is a domestic landrace found in the Van province of eastern Turkey. In this study, we aimed to determine the seasonal carriage of dermatophytes in Van cats without clinical lesions. A total of 264 hair specimens were collected from clinically healthy cats in and around the Van Province. Of these samples, 30.3% were obtained in spring, 30.6% in summer, 16.6% in autumn, and 22.3% in winter; 45.1% of samples were from male cats and the rest from female ones. Of the studied cats, 118 were younger than 1 year, 78 were 1-3 years old, and 68 were older than 3 years. The specimens were subjected to direct microscopic examination with 15% potassium hydroxide and cultured on Sabouraud dextrose agar and dermatophyte test medium supplemented with cycloheximide and chloramphenicol. Dermatophyte identification was carried out based on macroscopic and microscopic colony morphology, urease activities, in vitro hair perforation test, growth at 37°C, and pigmentation on corn meal agar. Dermatophytes were isolated from 19 (7.1%) of the 264 specimens examined. The most frequently isolated fungi were Trichophyton terrestre (4.1%), followed by Microsporum gypseum (1.1%), M. nanum (1.1%), and T. mentagrophytes (0.7%), and these fungi may represent a health risk for humans in contact with clinically healthy Van cats. M. canis was not isolated from any of the specimens. Our results show no significant (p>0.05) association between carriage of dermatophytes and the gender of cats. The carriage rate of dermatophytes was high in spring and winter, and the only possible risk factor for infection was age of the animal. PMID:26887249

  20. Did Van Gogh have Ménière's disease?

    PubMed

    Martin, C

    2011-09-01

    Very surprising diagnoses have sometimes been made of the illness from which Vincent van Gogh suffered. Most of them can be safely ignored; the diagnosis of Ménière's disease, however, put forward by K. I. Arenberg, deserves attention. This diagnosis was first criticized in a doctoral thesis in 1992 in the university of Saint-Etienne (France), and again in a book published by Henri André Martin in 1994, and the present study is based on these. Analyzing van Gogh's pathology presupposes awareness of the family context in which he lived, his eventful life, his artistic career and of his correspondence, which notably provides no support for a diagnosis of Ménière's disease. Analysis, indeed, enables Ménière's disease to be categorically eliminated in favor of temporal epilepsy, as confirmed in 1956 by Gastaut following the diagnosis initially made half a century earlier by Dr Rey. Van Gogh's illness is an example of the contradictory changes in affect, behavior and personality to be observed in epileptic patients. Absinth intoxication doubtless aggravated van Gogh's epilepsy and may account for certain prolonged episodes of confusion. It would be wrong, however, to speak of alcoholic dementia rather than of a probable epileptic psychosis or other pathology such as hallucinatory psychosis, or delirious attack, either isolated or related to late-onset schizophrenia. Apart from certain episodes of severe mental disorder, however, van Gogh's exceptional creativity was maintained up to the very end. Like any other artist, his temperament was expressed in his art, exalted rather than impaired by his illness. PMID:21616739

  1. The Peter Pan paradigm.

    PubMed

    Cohen, J Craig; Larson, Janet E

    2008-01-01

    Genetic and environmental agents that disrupt organogenesis are numerous and well described. Less well established, however, is the role of delay in the developmental processes that yield functionally immature tissues at birth. Evidence is mounting that organs do not continue to develop postnatally in the context of these organogenesis insults, condemning the patient to utilize under-developed tissues for adult processes. These poorly differentiated organs may appear histologically normal at birth but with age may deteriorate revealing progressive or adult-onset pathology. The genetic and molecular underpinning of the proposed paradigm reveals the need for a comprehensive systems biology approach to evaluate the role of maternal-fetal environment on organogenesis."You may delay, but time will not" Benjamin Franklin, USA Founding Father. PMID:18182112

  2. Reproduction of Blackfin tuna Thunnus atlanticus (Perciformes: Scombridae) in Saint Peter and Saint Paul Archipelago, Equatorial Atlantic, Brazil.

    PubMed

    Bezerra, Natalia P A; Fernandes, Cezar A F; Albuquerque, Fernanda V; Pedrosa, Vanessa; Hazin, Fábio; Travassos, Paulo

    2013-09-01

    The reproduction of Blackfin tuna Thunnus atlanticus has been described for coastal regions, and for a long time, this species was considered to be a strictly continental spawner. Recently, this species was observed around a seamount habitat 500 nautical miles Northeast of Brazil, located between South America and Africa. In this study we describe the reproductive biology of Blackfin tuna at Saint Peter and Saint Paul Archipelago (SPSPA). Male and female gonads were sampled from December 2008 to July 2010, and analyzed macro and microscopically. A total of 361 fish were sampled (247 males and 114 females). Males were more common than females, with a sex ratio of 2.2 male:1 female. The fork length (FL) of all sampled specimens ranged from 38 to 98cm, and larger length classes were more frequent in males. It was possible to distinguish six maturity phases for females: immature, developing, spawning capable, actively spawning, regressing and recovering. Five phases were identified for males: immature, developing, spawning capable, actively spawning and recovering. The gonad index (GI) mean monthly values ranged from 6.6 (SD = 4.1) to 58.4 (SD = 34.7) for females, and from 2.6 (SD = 1.3) to 66.2 (SD = 30.4) for males. For both sexes, the largest GI values were observed at the beginning of the first semester of the year. Size at first maturity was estimated at 48cm FL and 55cm FL for females and males respectively. Approximately 80% of the specimens were adults and considered to be in reproductive conditions. Histological analysis of the ovaries and testes showed that most of the specimens were sexually mature and were reproductively active during all months of the year. However, females with mature ovaries, with large amounts of hydrated oocytes and post-ovulatory follicles, were mainly found from December to March, thus these months may constitute the main spawning season in SPSPA. Batch fecundity varied between 272025 and 1,140584 oocytes for 56 and 68 cm FL females

  3. Karyotypic variation in Rhinophylla pumilio Peters, 1865 and comparative analysis with representatives of two subfamilies of Phyllostomidae (Chiroptera)

    PubMed Central

    Gomes, Anderson José Baia; Nagamachi, Cleusa Yoshiko; Rodrigues, Luís Reginaldo Ribeiro; Farias, Solange Gomes; Rissino, Jorge Dores; Pieczarka, Julio Cesar

    2012-01-01

    Abstract The family Phyllostomidae belongs to the most abundant and diverse group of bats in the Neotropics with more morphological traits variation at the family level than any other group within mammals. In this work, we present data of chromosome banding (G, C and Ag-NOR) and Fluorescence In Situ Hybridization (FISH) for representatives of Rhinophylla pumilio Peters, 1865 collected in four states of Brazil (Amazonas, Bahia, Mato Grosso and Pará). Two karyomorphs were found in this species: 2n=34, FN=64 in populations from western Pará and Mato Grosso states and 2n=34, FN=62 from Amazonas, Bahia, and northeastern Pará and Marajó Island (northern). Difference in the Fundamental Number is determined by variation in the size of the Nucleolar Organizer Region (NOR) accompanied with heterochromatin on chromosomes of pair 16 or, alternatively, a pericentric inversion. The C-banding technique detected constitutive heterochromatin in the centromeric regions of all chromosomes and on the distal part of the long arm of pair 15 of specimens from all localities. FISH with a DNA telomeric probe did not show any interstitial sequence, and an 18S rDNA probe and silver staining revealed the presence of NOR in the long arm of the pair 15, associated with heterochromatin, and in the short arm of the pair 16 for all specimens. The intra-specific analysis using chromosome banding did not show any significant difference between the samples. The comparative analyses using G-banding have shown that nearly all chromosomes of Rhinophylla pumilio were conserved in the chromosome complements of Glossophaga soricina Pallas, 1766, Phyllostomus hastatus Pallas, 1767, Phyllostomus discolor Wagner, 1843 and Mimon crenulatum Geoffroy, 1801, with a single chromosomal pair unique to Rhinophylla pumilio (pair 15). However, two chromosomes of Mimon crenulatum are polymorphic for two independent pericentric inversions. The karyotype with 2n=34, NF=62 is probably the ancestral one for the other

  4. mtDNA perspective of chromosomal diversification and hybridization in Peters' tent-making bat (Uroderma bilobatum: Phyllostomidae).

    PubMed

    Hoffmann, Federico G; Owen, James G; Baker, Robert J

    2003-11-01

    We compared sequence variation in the complete mitochondrial cytochrome-b gene with chromosomal and geographical variation for specimens of Peters' tent-making bat (Uroderma bilobatum). Three different chromosomal races have been described in this species: a 2n = 42 race from South America east of the Andes, a 2n = 44 from NW Central America and 2n = 38 from the rest of Central America and NW South America. The deepest nodes in the tree were found within the South American race (42 race), which is consistent with a longer history of this race. Average distance among races ranged from 2.5 to 2.9%, with the highest amount of intraracial variation found within the 2n = 42 race (1.7%), intermediate values within the 2n = 38 race (0.9%) and lowest within the 2n = 44 race (0.5%). Variation among chromosomal races accounted for over 55% of molecular variance, whereas variation among populations within races accounted for 6%. The 2n = 38 and 2n = 44 races hybridize in the coastal lowlands of Honduras, near the Gulf of Fonseca. Introgression between these two races is low (two introgressed individuals in 45 examined). Clinal variation across the hybrid zone for the cytochrome-b of U. bilobatum, is similar to clinal variation reported for chromosomes and isozymes of this species. Mismatch distribution analyses suggests that geographical isolation and karyological changes have interplayed in a synergistic fashion. Fixation of the alternative chromosomal rearrangements in geographical isolation and secondary contact is the most likely mechanism accounting for the hybrid zone between the 2n = 38 and 2n = 44 races. If a molecular clock is assumed, with rates ranging from 2.3 to 5.0% per million years, then isolation between these races occurred within the last million years, implying a relatively recent origin of the extant diversity in Uroderma bilobatum. None the less, the three chromosomal races probably represent three different biological species. PMID:14629379

  5. Obituary: Leon Van Speybroeck, 1935-2002

    NASA Astrophysics Data System (ADS)

    Gorenstein, Paul; Tananbaum, Harvey Dale

    2003-12-01

    Leon Van Speybroeck, a master designer of X-ray telescope mirrors and the telescope scientist for the Chandra X-ray Observatory, died in Newton, Massachusetts, on 25 December 2002, shortly after learning that he had metastatic melanoma. Leon was born on 27 August 1935 in Wichita, Kansas. His father, Paul, was Assistant Treasurer and head of the accounting department at Beech Aircraft, and his mother, Anna Florence (Utley), was a homemaker. Both parents died in 1996. Leon's younger sister, Saundra, is a nurse and his younger brother, John, is a surgeon. Leon received a BS in 1957 and a PhD in 1965, both in physics, from MIT. His PhD thesis, ``Elastic Electron-Deuteron Scattering at High Momentum Transfer," was carried out under the supervision of Henry Kendall and Jerome Friedman. Leon spent two more years at MIT as a research associate. In 1967, he was hired by American Science and Engineering (AS&E) in Cambridge, Massachusetts, and joined the X-ray astronomy group led by Riccardo Giacconi, who received the 2002 Nobel Prize in Physics for contributions to astrophysics that led to the discovery of cosmic X-ray sources. Leon soon became involved in the design and construction of high-resolution, grazing-incidence X-ray telescopes, starting with the Apollo Telescope Mount flown on NASA's Skylab from 1973 to 1974. A series of high-resolution X-ray images of the solar corona led to dramatic changes in ideas about the solar corona, with new emphasis on magnetic dynamo processes. When the Smithsonian Astrophysical Observatory and the Harvard College Observatory morphed into the Harvard-Smithsonian Center for Astrophysics (CfA) in 1973, Leon, with Giacconi and other senior X-ray astronomers from AS&E, joined the CfA and formed the high-energy astrophysics division. Leon guided the design and development of the X-ray mirrors on NASA's Einstein Observatory, which was flown from 1978 to 1981 as the first cosmic X-ray observatory with an imaging telescope. Along the way, he

  6. Obituary: Thomas C. Van Flandern (1940-2009)

    NASA Astrophysics Data System (ADS)

    Dunham, David; Slabinski, Victor

    2011-12-01

    Dr. Thomas Charles Van Flandern, an expert in celestial mechanics and cosmology, died January 9, 2009 in Seattle, Washington, of colon cancer. He was 68. Van Flandern was an astronomer at the U.S. Naval Observatory from 1963 to 1983. He developed software to predict and analyze lunar occultations to improve lunar orbital and fundamental star catalog data. In later years he championed increasingly controversial theories. But his 1978 prediction that some asteroids have natural satellites, which was almost universally rejected, was verified when the Galileo spacecraft photographed Dactyl, a satellite of (243) Ida, during its flyby in 1993. Besides astronomy and computers, he had strong interests in biochemistry and nutrition, and he ran a business selling personal computers in the 1980s. Tom Van Flandern was born June 26, 1940 in Cleveland, Ohio, the first child of Robert F. Van Flandern and Anna Mary Haley. His father, a police officer, left the family when Tom Van Flandern was 5. His mother died when he was 16; he and his siblings then lived with their grandmother, Margery Jobe, until he went to college. Tom Van Flandern became interested in astronomy as a child. He used his first telescope, purchased with newspaper delivery earnings, to observe lunar occultations, and then learned how to predict them, sparking a life-long passion for dynamical astronomy. While attending St. Ignatius High School, Van Flandern and fellow student Thomas Petrie organized the Cleveland Moonwatch team to observe the first artificial satellites, the only team without an adult organizer. In 1958, Tom Van Flandern entered Xavier University where he led the Cincinnati Moonwatch team. He learned computer programming at a summer job with General Electric and wrote software to calculate "look angles" from orbital elements. The Cincinnati team became a top producer of observations using these predictions. Tom obtained a B.S. in mathematics from Xavier in 1962. He spent the next year at

  7. Reply to comment by Peters et al. (2015) on "Cosmogenic 180W variations in meteorites and re-assessment of a possible 184Os-180W decay system"

    NASA Astrophysics Data System (ADS)

    Cook, David L.; Kruijer, Thomas S.; Leya, Ingo; Kleine, Thorsten

    2015-11-01

    Peters et al. (2014) argued that ε180W excesses in iron meteorites originated as the decay product of 184Os. They also suggested that compositional heterogeneities, leading to variable Os/W ratios within a single iron, was the most likely explanation for discrepant ε180W values measured in different studies of the same meteorites. In Cook et al. (2014), we showed that irradiation by galactic cosmic rays (GCR) can induce large variations in ε180W. These effects provide at least a partial explanation for the observed ε180W excesses. Additionally, they can explain why ε180W values may vary both among members of a particular iron meteorite group (e.g., IVB irons), as well as between different specimens of a single iron meteorite (e.g., Weaver Mountains). We used GCR-corrected ε180W data to re-estimate the possible role of 184Os decay in generating ε180W excesses and found that any radiogenic production of 180W was much smaller than suggested by Peters et al. (2014). The preceding comment by Peters et al. (2015) on our 2014 paper contains criticisms that focus mainly on the following topics: the influence of an s-process deficit in W isotopes on ε180W in some iron meteorites, our sample selection for the construction of our isochron, and the potential effect of sample compositional heterogeneity on Os/W ratios and how this may impact our isochron slope. We address each of these in turn below.

  8. XRF investigation on skeletal remains from King Peter III of Aragon (1239-1285 A.D.) and Queen Blanche of Anjou (1280-1310 A.D.)

    NASA Astrophysics Data System (ADS)

    Piga, Giampaolo; Brunetti, Antonio; Lasio, Barbara; Enzo, Stefano; Malgosa, Assumpció

    2014-03-01

    We conducted an X-Ray Fluorescence investigation on bone fragments belonging to King Peter III of Aragon and Queen Blanche of Anjou. The spectroscopic analysis was carried out in selected points of the bone fragments. Several transitional elements normally unexpected in the bone composition have been found at varying level of concentration. The presence of these elements was interpreted in relation to chemical treatments for mummification of bodies as well as to dietary habits, including tools used for cooking and for the consumption of food.

  9. AVTA Federal Fleet PEV Readiness Data Logging and Characterization Study for Department of Veterans Affairs. James J. Peters VA Medical Center, Bronx, NY

    SciTech Connect

    Schey, Stephen; Francfort, Jim

    2014-10-01

    This report focuses on the Department of Veterans Affairs, James J. Peters VA Medical Center (VA - Bronx) fleet to identify daily operational characteristics of select vehicles and report findings on vehicle and mission characterizations to support the successful introduction of PEVs into the agencies’ fleets. Individual observations of these selected vehicles provide the basis for recommendations related to electric vehicle adoption and whether a battery electric vehicle or plug-in hybrid electric vehicle (collectively referred to as PEVs) can fulfill the mission requirements.

  10. Obituary: James Alfred Van Allen, 1914-2006

    NASA Astrophysics Data System (ADS)

    Ludwig, George H.; McIlwain, Carl Edwin

    2006-12-01

    James Alfred Van Allen, world-renowned space scientist, died 9 August 2006 at the age of ninety-one. He succumbed to heart failure after a ten-week period of declining health. Van Allen served for his entire sixty-seven-year professional career as an amazingly productive researcher, space science spokesman, inspired teacher, and valued colleague. The realization by him and his associates that charged particles are trapped by the Earth's magnetic field began a whole new field of research, magnetospheric physics. Following that initial discovery, he and his associates quickly extended their observations, first to the inner planets, and then to the rest of the planets and beyond. During his tenure at Iowa, he and his group flew instruments on more than sixty successful Earth satellites and planetary spacecraft, including the first missions to the planets Venus, Mars, Jupiter, Saturn, Uranus, and Neptune. Van Allen's lifetime publication list numbers more than 275, of which many are widely-cited, seminal papers. He was the sole author of more than 125 of those papers. Beyond the research laboratory, Van Allen worked energetically throughout his career in establishing space research as a new branch of human inquiry. He was among the most sought-after as a committee member and adviser, working at the highest levels of government, including the White House and Congress, and at all levels of the national and international research establishments. Many presentations in the non-scientific arena helped to bring the exciting discoveries and challenges of space research to the attention of the general public. James Van Allen (Van to his many friends and colleagues) was born on 7 September 1914 on a small farm near Mount Pleasant, Iowa, the second of four sons of Alfred Morris Van Allen and Alma Olney Van Allen. After high school in Mount Pleasant, he entered Iowa Wesleyan College, majoring in physics and graduating summa cum laude. While there, he was introduced to geophysics

  11. Photovoltaic Effect in an Electrically Tunable van der Waals Heterojunction

    PubMed Central

    2014-01-01

    Semiconductor heterostructures form the cornerstone of many electronic and optoelectronic devices and are traditionally fabricated using epitaxial growth techniques. More recently, heterostructures have also been obtained by vertical stacking of two-dimensional crystals, such as graphene and related two-dimensional materials. These layered designer materials are held together by van der Waals forces and contain atomically sharp interfaces. Here, we report on a type-II van der Waals heterojunction made of molybdenum disulfide and tungsten diselenide monolayers. The junction is electrically tunable, and under appropriate gate bias an atomically thin diode is realized. Upon optical illumination, charge transfer occurs across the planar interface and the device exhibits a photovoltaic effect. Advances in large-scale production of two-dimensional crystals could thus lead to a new photovoltaic solar technology. PMID:25057817

  12. IVAN: Intelligent Van for the Distribution of Pharmaceutical Drugs

    PubMed Central

    Moreno, Asier; Angulo, Ignacio; Perallos, Asier; Landaluce, Hugo; Zuazola, Ignacio Julio García; Azpilicueta, Leire; Astrain, José Javier; Falcone, Francisco; Villadangos, Jesús

    2012-01-01

    This paper describes a telematic system based on an intelligent van which is capable of tracing pharmaceutical drugs over delivery routes from a warehouse to pharmacies, without altering carriers' daily conventional tasks. The intelligent van understands its environment, taking into account its location, the assets and the predefined delivery route; with the capability of reporting incidences to carriers in case of failure according to the established distribution plan. It is a non-intrusive solution which represents a successful experience of using smart environments and an optimized Radio Frequency Identification (RFID) embedded system in a viable way to resolve a real industrial need in the pharmaceutical industry. The combination of deterministic modeling of the indoor vehicle, the implementation of an ad-hoc radiating element and an agile software platform within an overall system architecture leads to a competitive, flexible and scalable solution. PMID:22778659

  13. [Neuropsychiatry and creativity: "Starry night" of Van Gogh].

    PubMed

    Abundes-Corona, Rodolfo Arturo; Corona Vázquez, Teresa

    2014-01-01

    The life of Vincent van Gogh (1853-1890) has been studied thoroughly by humanists and scientists alike. His biography is an archetype of the relationship between creativity and disease. In 1956, Henri Gastaut defined his diagnosis as temporal lobe epilepsy. The artist was known for an eccentric personality and unpredictable mood, with recurrent psychotic bouts through the last two years of his life. Several authors have considered the possibility that van Gogh also suffered from bipolar affective disorder. We conducted a biographical and epistolary review with the objective of analyzing the complexity of his disease and the effects it had on his art, which ultimately placed him as one of the greatest geniuses in art. PMID:25098223

  14. Aqueous gating of van der Waals materials on bilayer nanopaper.

    PubMed

    Bao, Wenzhong; Fang, Zhiqiang; Wan, Jiayu; Dai, Jiaqi; Zhu, Hongli; Han, Xiaogang; Yang, Xiaofeng; Preston, Colin; Hu, Liangbing

    2014-10-28

    In this work, we report transistors made of van der Waals materials on a mesoporous paper with a smooth nanoscale surface. The aqueous transistor has a novel planar structure with source, drain, and gate electrodes on the same surface of the paper, while the mesoporous paper is used as an electrolyte reservoir. These transistors are enabled by an all-cellulose paper with nanofibrillated cellulose (NFC) on the top surface that leads to an excellent surface smoothness, while the rest of the microsized cellulose fibers can absorb electrolyte effectively. Based on two-dimensional van der Waals materials, including MoS2 and graphene, we demonstrate high-performance transistors with a large on-off ratio and low subthreshold swing. Such planar transistors with absorbed electrolyte gating can be used as sensors integrated with other components to form paper microfluidic systems. This study is significant for future paper-based electronics and biosensors. PMID:25283598

  15. Charge Transfer Excitons at van der Waals Interfaces.

    PubMed

    Zhu, Xiaoyang; Monahan, Nicholas R; Gong, Zizhou; Zhu, Haiming; Williams, Kristopher W; Nelson, Cory A

    2015-07-01

    The van der Waals interfaces of molecular donor/acceptor or graphene-like two-dimensional (2D) semiconductors are central to concepts and emerging technologies of light-electricity interconversion. Examples include, among others, solar cells, photodetectors, and light emitting diodes. A salient feature in both types of van der Waals interfaces is the poorly screened Coulomb potential that can give rise to bound electron-hole pairs across the interface, i.e., charge transfer (CT) or interlayer excitons. Here we address common features of CT excitons at both types of interfaces. We emphasize the competition between localization and delocalization in ensuring efficient charge separation. At the molecular donor/acceptor interface, electronic delocalization in real space can dictate charge carrier separation. In contrast, at the 2D semiconductor heterojunction, delocalization in momentum space due to strong exciton binding may assist in parallel momentum conservation in CT exciton formation. PMID:26001297

  16. Generalized van der Waals density functional theory for nonuniform polymers

    SciTech Connect

    Patra, Chandra N.; Yethiraj, Arun

    2000-01-15

    A density functional theory is presented for the effect of attractions on the structure of polymers at surfaces. The theory treats the ideal gas functional exactly, and uses a weighted density approximation for the hard chain contribution to the excess free energy functional. The attractive interactions are treated using a van der Waals approximation. The theory is in good agreement with computer simulations for the density profiles at surfaces for a wide range of densities and temperatures, except for low polymer densities at low temperatures where it overestimates the depletion of chains from the surface. This deficiency is attributed to the neglect of liquid state correlations in the van der Waals term of the free energy functional. (c) 2000 American Institute of Physics.

  17. Millimeter-wave rubidium Rydberg van der Waals spectroscopy

    SciTech Connect

    Han Jianing; Gallagher, T. F.

    2009-05-15

    We have observed the diatomic nsns{yields}ns(n+1)s{yields}(n+1)s(n+1)s microwave transitions of pairs of cold Rb Rydberg atoms for 36van der Waals shift due to its near degeneracy with the nearby np{sub 3/2}np{sub 3/2} state. In fact, the energy difference and the van der Waals shift change sign at n=38 and we observe shifts of both signs. The combined excitation of the ns(n+1)s and (n+1)s(n+1)s states leads to an unusual line shape which can be described by a three-level Floquet model.

  18. Van der Waals density functional applied to adsorption systems

    NASA Astrophysics Data System (ADS)

    Hamada, Ikutaro

    2013-03-01

    The van der Waals density functional (vdW-DF) is a promising density functional to describe the van der Waals forces within density functional theory. However, despite the recent efforts, there is still room for further improvement, especially for describing molecular adsorption on metal surfaces. I will show that by choosing appropriate exchange and nonlocal correlation functionals, it is possible to calculate geometries and electronic structures for adsorption systems accurately within the framework of vdW-DF. Applicability of the present approach will be illustrated with its applications to graphene/metal, fullerene/metal, and water/graphene interfaces. This work is partly supported by a Grant-in-Aid for Scientific Research on Innovative Area (No. 23104501). AIMR was established by the World Premier International Research Center Initiative (WPI), MEXT, Japan.

  19. Van der Waals interaction-tuned heat transfer in nanostructures

    NASA Astrophysics Data System (ADS)

    Sun, Tao; Wang, Jianxiang; Kang, Wei

    2012-12-01

    Interfaces usually impede heat transfer in heterogeneous structures. Recent experiments show that van der Waals (vdW) interactions can significantly enhance thermal conductivity parallel to the interface of a bundle of nanoribbons compared to a single layer of freestanding nanoribbon. In this paper, by simulating heat transfer in nanostructures based on a model of nonlinear one-dimensional lattices interacting via van der Waals interactions, we show that the vdW interface interaction can adjust the thermal conductivity parallel to the interface. The efficiency of the adjustment depends on the intensity of interactions and temperature. The nonlinear dependence of the conductivity on the intensity of interactions agrees well with experimental results for carbon nanotube bundles, multi-walled carbon nanotubes, multi-layer graphene, and nanoribbons.

  20. van der Waals explosion of cold Rydberg clusters

    NASA Astrophysics Data System (ADS)

    Faoro, R.; Simonelli, C.; Archimi, M.; Masella, G.; Valado, M. M.; Arimondo, E.; Mannella, R.; Ciampini, D.; Morsch, O.

    2016-03-01

    We report on the direct measurement in real space of the effect of the van der Waals forces between individual Rydberg atoms on their external degrees of freedom. Clusters of Rydberg atoms with interparticle distances of around 5 μ m are created by first generating a small number of seed excitations in a magneto-optical trap, followed by off-resonant excitation that leads to a chain of facilitated excitation events. After a variable expansion time the Rydberg atoms are field ionized, and from the arrival time distributions the size of the Rydberg cluster after expansion is calculated. Our experimental results agree well with a numerical simulation of the van der Waals explosion.

  1. Spin-Flavor van der Waals Forces and NN interaction

    SciTech Connect

    Alvaro Calle Cordon, Enrique Ruiz Arriola

    2011-12-01

    A major goal in Nuclear Physics is the derivation of the Nucleon-Nucleon (NN) interaction from Quantum Chromodynamics (QCD). In QCD the fundamental degrees of freedom are colored quarks and gluons which are confined to form colorless strongly interacting hadrons. Because of this the resulting nuclear forces at sufficiently large distances correspond to spin-flavor excitations, very much like the dipole excitations generating the van der Waals (vdW) forces acting between atoms. We study the Nucleon-Nucleon interaction in the Born-Oppenheimer approximation at second order in perturbation theory including the Delta resonance as an intermediate state. The potential resembles strongly chiral potentials computed either via soliton models or chiral perturbation theory and has a van der Waals like singularity at short distances which is handled by means of renormalization techniques. Results for the deuteron are discussed.

  2. Quantum field theory of van der Waals friction

    SciTech Connect

    Volokitin, A. I.; Persson, B. N. J.

    2006-11-15

    van der Waals friction between two semi-infinite solids, and between a small neutral particle and semi-infinite solid is studied using thermal quantum field theory in the Matsubara formulation. We show that the friction to linear order in the sliding velocity can be obtained from the equilibrium Green functions and that our treatment can be extended for bodies with complex geometry. The calculated friction agrees with the friction obtained using a dynamical modification of the Lifshitz theory, which is based on the fluctuation-dissipation theorem. We show that it should be possible to measure the van der Waals friction in noncontact friction experiment using state-of-the-art equipment.

  3. Van Allen Probes: Resolving Fundamental Physics with Practical Consequences

    NASA Astrophysics Data System (ADS)

    Ukhorskiy, Aleksandr; Sibeck, David; Fox, Nicola; Mauk, Barry; Kessel, Ramona

    The Van Allen Probes twin spacecraft were launched on 30 August 2012 into nearly identical, 1.1 x 5.8 Re elliptical, low inclination (10°) Earth orbits with one of the two spacecraft lapping the other about every 2.5 months. The goal of the mission is to provide understanding of how populations of relativistic electrons and penetrating ions in space form or change in response to variable inputs of energy from the Sun. In this paper we overview the new understanding and discoveries of the Van Allen Probes science investigations since the operational mission began on 1 November 2012, which include formation of multiple coherently ordered structures within the outer electron belt and new persistent “zebra stripes” in the inner electron belt.

  4. [Brown-Vialleto-van Laere syndrome: report of 2 cases].

    PubMed

    De Oliveira, J T; Moreira, P R; Cardoso, F; Perpétuo, F O

    1995-12-01

    Brown-Vialetto-van Laere syndrome is a rare hereditary or sporadic degenerative disorder characterised by progressive sensoryneural deafness, followed or accompanied by cranial nerve palsies. The anterior horn cells and the optic pathways may be involved in some cases. We report two cases, and comment the differential diagnosis and the relationships of this syndrome to the muscle spinal atrophies and the hereditary deafness. PMID:8729774

  5. Case report: Multimodality imaging of van Neck-Odelberg disease

    PubMed Central

    Macarini, Luca; Lallo, Tania; Milillo, Paola; Muscarella, Silvana; Vinci, Roberta; Stoppino, Luca P

    2011-01-01

    Synchondrosis ischiopubic syndrome (SIS), also known as van Neck–Odelberg disease, is a syndrome characterized by an atypical ossification pattern of the ischiopubic synchondrosis. Its radiological features may mimic stress fracture, neoplasm, osteomyelitis, or posttraumatic osteolysis, causing problems in diagnosis, sometimes leading to unnecessary workup. We report two cases in which the correlation between the clinical and multimodality imaging data enabled the correct diagnosis of SIS. PMID:21799592

  6. Case report: Multimodality imaging of van Neck-Odelberg disease.

    PubMed

    Macarini, Luca; Lallo, Tania; Milillo, Paola; Muscarella, Silvana; Vinci, Roberta; Stoppino, Luca P

    2011-04-01

    Synchondrosis ischiopubic syndrome (SIS), also known as van Neck-Odelberg disease, is a syndrome characterized by an atypical ossification pattern of the ischiopubic synchondrosis. Its radiological features may mimic stress fracture, neoplasm, osteomyelitis, or posttraumatic osteolysis, causing problems in diagnosis, sometimes leading to unnecessary workup. We report two cases in which the correlation between the clinical and multimodality imaging data enabled the correct diagnosis of SIS. PMID:21799592

  7. A van der Waals free energy in electrolytes revisited

    NASA Astrophysics Data System (ADS)

    Jancovici, B.

    2006-01-01

    A system of three electrolytes separated by two parallel planes is considered. Each region is described by a dielectric constant and a Coulomb fluid in the Debye-Hückel regime. In their book Dispersion Forces, Mahanty and Ninham have given the van der Waals free energy of this system. We rederive this free energy by a different method, using linear response theory and the electrostatic Maxwell stress tensor for obtaining the dispersion force.

  8. Structure and dynamics of small van der Waals complexes

    SciTech Connect

    Loreau, J.

    2014-10-06

    We illustrate computational aspects of the calculation of the potential energy surfaces of small (up to five atoms) van der Waals complexes with high-level quantum chemistry techniques such as the CCSD(T) method with extended basis sets. We discuss the compromise between the required accuracy and the computational time. Further, we show how these potential energy surfaces can be fitted and used in dynamical calculations such as non-reactive inelastic scattering.

  9. A proof of van Aubel's theorem using orthogonal vectors

    NASA Astrophysics Data System (ADS)

    Glaister, P.

    2016-04-01

    We show how two linearly independent vectors can be used to construct two orthogonal vectors of equal magnitude in a simple way. The proof that the constructed vectors are orthogonal and of equal magnitude is a good exercise for students studying properties of scalar and vector triple products. We then show how this result can be used to prove van Aubel's theorem that relates the two line segments joining the centres of squares on opposite sides of a plane quadrilateral.

  10. Van der Waals and Casimir-Polder interactions between neutrons

    NASA Astrophysics Data System (ADS)

    Babb, James F.; Hussein, Mahir S.

    2016-03-01

    We investigate the van der Waals interaction between neutrons using the theory of Casimir and Polder, wherein the potential for asymptotically large separations falls off as the inverse seventh power, and compare it to the similar interaction between a neutron and a proton, for which the asymptotic interaction falls off as the inverse fourth power. Modifications of the formalism to extend the validity to smaller separations using dynamic electric and magnetic dipole polarizability data are discussed.

  11. Protective effect of Punica granatum peel and Vitis vinifera seeds on DEN-induced oxidative stress and hepatocellular damage in rats.

    PubMed

    Kumar, Ashok K; Vijayalakshmi, K

    2015-01-01

    This study was designed to find out the efficacy of ethanol extracts of Punica granatum peel and Vitis vinifera seeds on diethylnitrosamine (DEN)-induced oxidative stress and hepatocellular damage in Wistar rats. Rats were divided into four groups. The first group served as normal control, and the second group received DEN at a dose of 200 mg/kg body weight by single intraperitoneal administration. The third one received DEN as in DEN-treated group and co-treated with 400 mg/kg P. granatum peel extract. The final group also received DEN and co-treated with 400 mg/kg V. vinifera seed extract. DEN administration to rats resulted in significantly elevated levels of serum SGPT, SGOT, ALP, and GGT which is indicative of hepatocellular damage. DEN-induced oxidative stress was confirmed by elevated levels of lipid peroxides and decreased activities of superoxide dismutase, catalase, and glutathione peroxidase in the serum and liver tissues. The status of non-enzymatic antioxidants like vitamin C, vitamin E, and reduced glutathione were also found to be decreased in serum and tissues of DEN-administered rats. Co-treatment with the P. granatum peel and V. vinifera seed extracts orally for 12 weeks significantly reversed the DEN-induced alterations in the serum and liver tissues. PMID:25304489

  12. Observation of van Hove Singularities in Twisted Silicene Multilayers

    PubMed Central

    2016-01-01

    Interlayer interactions perturb the electronic structure of two-dimensional materials and lead to new physical phenomena, such as van Hove singularities and Hofstadter’s butterfly pattern. Silicene, the recently discovered two-dimensional form of silicon, is quite unique, in that silicon atoms adopt competing sp2 and sp3 hybridization states leading to a low-buckled structure promising relatively strong interlayer interaction. In multilayer silicene, the stacking order provides an important yet rarely explored degree of freedom for tuning its electronic structures through manipulating interlayer coupling. Here, we report the emergence of van Hove singularities in the multilayer silicene created by an interlayer rotation. We demonstrate that even a large-angle rotation (>20°) between stacked silicene layers can generate a Moiré pattern and van Hove singularities due to the strong interlayer coupling in multilayer silicene. Our study suggests an intriguing method for expanding the tunability of the electronic structure for electronic applications in this two-dimensional material. PMID:27610412

  13. Observation of van Hove Singularities in Twisted Silicene Multilayers.

    PubMed

    Li, Zhi; Zhuang, Jincheng; Chen, Lan; Ni, Zhenyi; Liu, Chen; Wang, Li; Xu, Xun; Wang, Jiaou; Pi, Xiaodong; Wang, Xiaolin; Du, Yi; Wu, Kehui; Dou, Shi Xue

    2016-08-24

    Interlayer interactions perturb the electronic structure of two-dimensional materials and lead to new physical phenomena, such as van Hove singularities and Hofstadter's butterfly pattern. Silicene, the recently discovered two-dimensional form of silicon, is quite unique, in that silicon atoms adopt competing sp(2) and sp(3) hybridization states leading to a low-buckled structure promising relatively strong interlayer interaction. In multilayer silicene, the stacking order provides an important yet rarely explored degree of freedom for tuning its electronic structures through manipulating interlayer coupling. Here, we report the emergence of van Hove singularities in the multilayer silicene created by an interlayer rotation. We demonstrate that even a large-angle rotation (>20°) between stacked silicene layers can generate a Moiré pattern and van Hove singularities due to the strong interlayer coupling in multilayer silicene. Our study suggests an intriguing method for expanding the tunability of the electronic structure for electronic applications in this two-dimensional material. PMID:27610412

  14. Mid infrared observations of Van Maanen 2: no substellar companion.

    SciTech Connect

    Farihi, J; Becklin, E; Macintosh, B

    2004-11-03

    The results of a comprehensive infrared imaging search for the putative 0.06 M{sub {circle_dot}} astrometric companion to the 4.4 pc white dwarf van Mannen 2 are reported. Adaptive optics images acquired at 3.8 {micro}m reveal a diffraction limited core of 0.09 inch and no direct evidence of a secondary. Models predict that at 5 Gyr, a 50 M{sub J} brown dwarf would be only 1 magnitude fainter than van Maanen 2 at this wavelength and the astrometric analysis suggested a separation of 0.2 inch. In the case of a chance alignment along the line of sight, a 0.4 mag excess should be measured. An independent photometric observation at the same wavelength reveals no excess. In addition, there exist published ISO observations of van Maanen 2 at 6.8 {micro}m and 15.0 {micro}m which are consistent with photospheric flux of a 6750 K white dwarf. If recent brown dwarf models are correct, there is no substellar companion with T{sub eff} {approx}> 500 K.

  15. Van Allen Probes Science Gateway and Space Weather Data Processing

    NASA Astrophysics Data System (ADS)

    Romeo, G.; Barnes, R. J.; Weiss, M.; Fox, N. J.; Mauk, B.; Potter, M.; Kessel, R.

    2014-12-01

    The Van Allen Probes Science Gateway acts as a centralized interface to the instrument Science Operation Centers (SOCs), provides mission planning tools, and hosts a number of science related activities such as the mission bibliography. Most importantly, the Gateway acts as the primary site for processing and delivering the VAP Space Weather data to users. Over the past year, the web-site has been completely redesigned with the focus on easier navigation and improvements of the existing tools such as the orbit plotter, position calculator and magnetic footprint tool. In addition, a new data plotting facility has been added. Based on HTML5, which allows users to interactively plot Van Allen Probes summary and space weather data. The user can tailor the tool to display exactly the plot they wish to see and then share this with other users via either a URL or by QR code. Various types of plots can be created, including simple time series, data plotted as a function of orbital location, and time versus L-Shell. We discuss the new Van Allen Probes Science Gateway and the Space Weather Data Pipeline.

  16. Nonadiabatic Van der Pol oscillations in molecular transport

    NASA Astrophysics Data System (ADS)

    Kartsev, Alexey; Verdozzi, Claudio; Stefanucci, Gianluca

    2014-01-01

    The force exerted by the electrons on the nuclei of a current-carrying molecular junction can be manipulated to engineer nanoscale mechanical systems. In the adiabatic regime a peculiarity of these forces is negative friction, responsible for Van der Pol oscillations of the nuclear coordinates. In this work we study the robustness of the Van der Pol oscillations against high-frequency sources. For this purpose we go beyond the adiabatic approximation and perform full Ehrenfest dynamics simulations. The numerical scheme implements a mixed quantum-classical algorithm for open systems and is capable to deal with arbitrary time-dependent driving fields. We find that the Van der Pol oscillations are extremely stable. The nonadiabatic electron dynamics distorts the trajectory in the momentum-coordinate phase space but preserves the limit cycles in an average sense. We further show that high-frequency fields change both the oscillation amplitudes and the average nuclear positions. By switching the fields off at different times one obtains cycles of different amplitudes which attain the limit cycle only after considerably long times.

  17. Global empirical models of plasmaspheric hiss using Van Allen Probes

    NASA Astrophysics Data System (ADS)

    Spasojevic, M.; Shprits, Y. Y.; Orlova, K.

    2015-12-01

    Plasmaspheric hiss is a whistler-mode emission that permeates the Earth's plasmasphere and is a significant driver of energetic electron losses through cyclotron resonant pitch angle scattering. The Electric and Magnetic Field Instrument Suite and Integrated Science instrument on the Van Allen Probes mission provides vastly improved measurements of the hiss wave environment including continuous measurements of the wave magnetic field cross-spectral matrix and enhanced low-frequency coverage. Here, we develop empirical models of hiss wave intensity using two years of Van Allen Probes data. First, we describe the construction of the hiss database. Then, we compare the hiss spectral distribution and integrated wave amplitude obtained from Van Allen Probes to those previously extracted from the Combined Release and Radiation Effects Satellite mission. Next, we develop a cubic regression model of the average hiss magnetic field intensity as a function of Kp, L, magnetic latitude, and magnetic local time. We use the full regression model to explore general trends in the data and use insights from the model to develop a simplified model of wave intensity for straightforward inclusion in quasi-linear diffusion calculations of electron scattering rates.

  18. Dens Axis Vertebroplasty Combined with C 3 Vertebral Body Arthroplasty. Case Study.

    PubMed

    Guzik, Grzegorz

    2015-01-01

    Spinal tumors are most commonly located in the thoracic and lumbar spine, less commonly in the cervical section of the spine. Diagnosis is usually late and surgery is not radical. Myeloma is one of the most frequent metastatic spinal tumors. Surgical treatment of osteolytic lesions in the spine involves posterior and anterior stabilization, full or partial tumorectomies as well as decompression of neural structures. Bone cement injection has been increasingly used in plastic surgery of vertebral bodies and is most frequently performed percutaneously in the thoracic and lumbar spine. Cervical vertebroplasty can be performed both percutaneously and after anterior exposure of the spine. The dens axis can also be approached transorally. The safest surgical technique seems to be the Southwick approach, which allows exposure of the spine at C2-Th2 and, if necessary, can be extended both proximally and distally. Cemented cervical vertebroplasty, especially dens axis vertebroplasty, shows good results, yet this technique has rarely been described in the literature. It has the advantage of early patient mobility and little limitation of motion of the spine. Cervical vertebroplasty can be successfully combined with other procedures utilizing the same surgical approach in a single-stage operation. Post-resection anterior stabilization of the cervical spine with plates and vertebral body prosthesis allows for good stability of the spine and makes it possible to restore the spinal axis and curvatures. PMID:26468178

  19. Bacoside A downregulates matrix metalloproteinases 2 and 9 in DEN-induced hepatocellular carcinoma.

    PubMed

    Janani, Panneerselvam; Sivakumari, Kanakarajan; Geetha, Arumugam; Yuvaraj, Sambandam; Parthasarathy, Chandrakesan

    2010-03-01

    Cancer metastasis is a complex multi-step process, responsible for a majority of cancer-related deaths by affecting the critical organs and causing complications in therapies. Hepatocellular carcinoma is a multi-factorial disease and is the third most common cause of cancer related mortality worldwide. Clinical and experimental studies have shown that MMP-2 and MMP-9 are involved in tumor invasion and metastases and their elevated expression has been associated with poor prognosis. Our recent studies showed a strong anti-oxidant and hepatoprotective effects of bacoside A (BA) against carcinogen. Nevertheless the effect of BA on the activities and expression of MMP-2 and MMP-9 during hepatocellular carcinoma is not yet recognized. Therefore, the present study was designed to assess the same. Results of gelatin zymography study showed that BA co-treatment significantly decreased the activities of MMP-2 and MMP-9, which is increased during hepatocellular carcinoma. Further immunoblot analysis showed decreased expression of MMP-2 and MMP-9 in rats co-treated with BA compared to DEN-induced hepatocellular carcinoma. Our results reveal that BA exerts its anti-metastatic effect against DEN-induced hepatocellular carcinoma by inhibiting the activities and expressions of MMP-2 and MMP-9. PMID:20084675

  20. Wie verstehen Schülerinnen und Schüler den Begriff der Unendlichkeit?

    NASA Astrophysics Data System (ADS)

    Schimmöller, Tabea

    Wie Hilbert bereits feststellte, wirkt die Idee der Unendlichkeit, wie keine andere, schon seit Zeiten sehr anregend und fruchtbar auf den Verstand und bewegt das Gemüt der Menschen. Der Begriff der Unendlichkeit bedarf aber auch, wie kein anderer, der Aufklärung, denn mit ihm eröffnet sich ein weites Feld, welches nicht nur aus vielen verschiedenen Definitionen besteht, sondern auch aus völlig unterschiedlichen Disziplinen. Physiker suchen immer dringender nach einer "Theorie für Alles" oder einer "Weltformel", Kosmologen beschäftigen sich unter anderem mit der Ewigkeit des Universums, Theologen interessiert eher die Unendlichkeit Gottes, Philosophen diskutieren unter anderem Grenzfragen zwischen Naturwissenschaft und Philosophie und die Mathematiker versuchen den Paradoxien des Unendlichen einen Sinn zu geben. Und so wird ersichtlich, dass nichts abstrakter ist als das Unendliche: Obwohl die Unendlichkeit für die unterschiedlichsten Wissenschaften von großer Bedeutung ist, "[ist] in der Wirklichkeit das Unendliche nirgends zu finden, [egal] was für Erfahrungen und Beobachtungen und welcherlei Wissenschaft wir auch heranziehen".