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Sample records for phraseology general principles

  1. Itch Management: General Principles.

    PubMed

    Misery, Laurent

    2016-01-01

    Like pain, itch is a challenging condition that needs to be managed. Within this setting, the first principle of itch management is to get an appropriate diagnosis to perform an etiology-oriented therapy. In several cases it is not possible to treat the cause, the etiology is undetermined, there are several causes, or the etiological treatment is not effective enough to alleviate itch completely. This is also why there is need for symptomatic treatment. In all patients, psychological support and associated pragmatic measures might be helpful. General principles and guidelines are required, yet patient-centered individual care remains fundamental. PMID:27578069

  2. Phraseology in Planned Languages.

    ERIC Educational Resources Information Center

    Fiedler, Sabine

    1999-01-01

    A comprehensive phraseological study of Esperanto, based on detailed test analyses, participant observation and surveys, reveals both similarities and differences in comparison to ethnic or national languages. Relatively high level of metalinguistic consciousness and creativity were observed, coupled with widely differing attitudes towards the…

  3. Archimedes' Principle in General Coordinates

    ERIC Educational Resources Information Center

    Ridgely, Charles T.

    2010-01-01

    Archimedes' principle is well known to state that a body submerged in a fluid is buoyed up by a force equal to the weight of the fluid displaced by the body. Herein, Archimedes' principle is derived from first principles by using conservation of the stress-energy-momentum tensor in general coordinates. The resulting expression for the force is…

  4. The Principle of General Tovariance

    NASA Astrophysics Data System (ADS)

    Heunen, C.; Landsman, N. P.; Spitters, B.

    2008-06-01

    We tentatively propose two guiding principles for the construction of theories of physics, which should be satisfied by a possible future theory of quantum gravity. These principles are inspired by those that led Einstein to his theory of general relativity, viz. his principle of general covariance and his equivalence principle, as well as by the two mysterious dogmas of Bohr's interpretation of quantum mechanics, i.e. his doctrine of classical concepts and his principle of complementarity. An appropriate mathematical language for combining these ideas is topos theory, a framework earlier proposed for physics by Isham and collaborators. Our principle of general tovariance states that any mathematical structure appearing in the laws of physics must be definable in an arbitrary topos (with natural numbers object) and must be preserved under so-called geometric morphisms. This principle identifies geometric logic as the mathematical language of physics and restricts the constructions and theorems to those valid in intuitionism: neither Aristotle's principle of the excluded third nor Zermelo's Axiom of Choice may be invoked. Subsequently, our equivalence principle states that any algebra of observables (initially defined in the topos Sets) is empirically equivalent to a commutative one in some other topos.

  5. Generalized Edgeworth-Pareto principle

    NASA Astrophysics Data System (ADS)

    Noghin, V. D.

    2015-12-01

    The general multicriteria choice problem with m individual preference relations and an asymmetric collective preference relation is considered. The concept of a k-effective alternative is introduced, which coincides with an effective alternative for k = 1 and represents a weakly effective alternative for k = m. For the other integer values of k, it lies somewhere in between. In terms of the general multicriteria choice problem, the Pareto axiom and the exclusion axiom for dominated alternatives are stated. Assuming that these axioms hold, a generalized Edgeworth-Pareto principle is established, which was earlier introduced by the author in the special case k = 1. The results are extended to a fuzzy collective preference relation and to a fuzzy set of initial alternatives.

  6. General principles of antimicrobial therapy.

    PubMed

    Leekha, Surbhi; Terrell, Christine L; Edson, Randall S

    2011-02-01

    Antimicrobial agents are some of the most widely, and often injudiciously, used therapeutic drugs worldwide. Important considerations when prescribing antimicrobial therapy include obtaining an accurate diagnosis of infection; understanding the difference between empiric and definitive therapy; identifying opportunities to switch to narrow-spectrum, cost-effective oral agents for the shortest duration necessary; understanding drug characteristics that are peculiar to antimicrobial agents (such as pharmacodynamics and efficacy at the site of infection); accounting for host characteristics that influence antimicrobial activity; and in turn, recognizing the adverse effects of antimicrobial agents on the host. It is also important to understand the importance of antimicrobial stewardship, to know when to consult infectious disease specialists for guidance, and to be able to identify situations when antimicrobial therapy is not needed. By following these general principles, all practicing physicians should be able to use antimicrobial agents in a responsible manner that benefits both the individual patient and the community. PMID:21282489

  7. Quantum mechanics and the generalized uncertainty principle

    SciTech Connect

    Bang, Jang Young; Berger, Micheal S.

    2006-12-15

    The generalized uncertainty principle has been described as a general consequence of incorporating a minimal length from a theory of quantum gravity. We consider a simple quantum mechanical model where the operator corresponding to position has discrete eigenvalues and show how the generalized uncertainty principle results for minimum uncertainty wave packets.

  8. General Biology Needs Well-Defined Principles

    ERIC Educational Resources Information Center

    Lewis, Ralph W.

    1973-01-01

    General biology courses should be planned and taught in colleges according to widely accepted theories and laws of biology. A list of 24 such principles is provided around which general biology courses could be structured. (PS)

  9. 39 CFR 268.1 - General principles.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false General principles. 268.1 Section 268.1 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION PRIVACY OF INFORMATION-EMPLOYEE RULES OF CONDUCT § 268.1 General principles. In order to conduct its business, the Postal Service has the need to collect various types of...

  10. 23 CFR 660.509 - General principles.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false General principles. 660.509 Section 660.509 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS SPECIAL PROGRAMS (DIRECT FEDERAL) Defense Access Roads § 660.509 General principles. (a) State and local...

  11. 23 CFR 660.509 - General principles.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false General principles. 660.509 Section 660.509 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS SPECIAL PROGRAMS (DIRECT FEDERAL) Defense Access Roads § 660.509 General principles. (a) State and local...

  12. 23 CFR 660.509 - General principles.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false General principles. 660.509 Section 660.509 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS SPECIAL PROGRAMS (DIRECT FEDERAL) Defense Access Roads § 660.509 General principles. (a) State and local...

  13. 23 CFR 660.509 - General principles.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false General principles. 660.509 Section 660.509 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS SPECIAL PROGRAMS (DIRECT FEDERAL) Defense Access Roads § 660.509 General principles. (a) State and local...

  14. 23 CFR 660.509 - General principles.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false General principles. 660.509 Section 660.509 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS SPECIAL PROGRAMS (DIRECT FEDERAL) Defense Access Roads § 660.509 General principles. (a) State and local...

  15. Deriving and applying generally applicable safety principles

    SciTech Connect

    Spray, S.D.

    1998-08-01

    The nuclear detonation safety of modern nuclear weapons depends on a coordinated safety theme incorporating three general safety principles: isolation, inoperability, and incompatibility. The success of this approach has encouraged them to study whether these and/or other principles might be useful in other applications. Not surprisingly, no additional first-principles (based on physical laws) have been identified. However, a more widely applicable definition and application of the principle-based approach has been developed, resulting in a selection of strategies that are basically subsets and varied combinations of the more general principles above. However, identification of principles to be relied on is only one step in providing a safe design. As one other important example, coordinating overall architecture and strategy is essential: the authors term this a safety theme.

  16. Action principle for the generalized harmonic formulation of general relativity

    SciTech Connect

    Brown, J. David

    2011-10-15

    An action principle for the generalized harmonic formulation of general relativity is presented. The action is a functional of the spacetime metric and the gauge source vector. An action principle for the Z4 formulation of general relativity has been proposed recently by Bona, Bona-Casas, and Palenzuela. The relationship between the generalized harmonic action and the Bona, Bona-Casas, and Palenzuela action is discussed in detail.

  17. 29 CFR 2.11 - General principles.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false General principles. 2.11 Section 2.11 Labor Office of the Secretary of Labor GENERAL REGULATIONS Audiovisual Coverage of Administrative Hearings § 2.11 General... involve administrative hearings. If such administrative hearings are held, we encourage their...

  18. 29 CFR 2.11 - General principles.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true General principles. 2.11 Section 2.11 Labor Office of the Secretary of Labor GENERAL REGULATIONS Audiovisual Coverage of Administrative Hearings § 2.11 General... involve administrative hearings. If such administrative hearings are held, we encourage their...

  19. The Maximum Entropy Principle for Generalized Entropies

    NASA Astrophysics Data System (ADS)

    Tsukada, Makoto

    2008-03-01

    It is well known that Gibbs states and the Gaussian distribution are characterized by the maximum entropy principle. In this paper we discuss probability distributions which maximize generalized entropies including Rényi's and Tsal-lis's.

  20. 31 CFR 29.321 - General principle.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CERTAIN DISTRICT OF COLUMBIA RETIREMENT PROGRAMS Split Benefits Service Performed After June 30, 1997 § 29.321 General principle. Any service performed after June 30, 1997, may never be credited toward...

  1. 12 CFR 330.3 - General principles.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Board of Governors of the Federal Reserve System in Regulation D (12 CFR 204.8(a)(2)), or in any... 12 Banks and Banking 4 2011-01-01 2011-01-01 false General principles. 330.3 Section 330.3 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY...

  2. 39 CFR 602.1 - General principles.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Service UNITED STATES POSTAL SERVICE PROCUREMENT SYSTEM FOR THE U.S. POSTAL SERVICE: INTELLECTUAL PROPERTY RIGHTS OTHER THAN PATENTS INTELLECTUAL PROPERTY RIGHTS OTHER THAN PATENTS § 602.1 General principles. It is the policy of the Postal Service to secure full ownership rights for its intellectual...

  3. Generalized convective quasi-equilibrium principle

    NASA Astrophysics Data System (ADS)

    Yano, Jun-Ichi; Plant, Robert S.

    2016-03-01

    A generalization of Arakawa and Schubert's convective quasi-equilibrium principle is presented for a closure formulation of mass-flux convection parameterization. The original principle is based on the budget of the cloud work function. This principle is generalized by considering the budget for a vertical integral of an arbitrary convection-related quantity. The closure formulation includes Arakawa and Schubert's quasi-equilibrium, as well as both CAPE and moisture closures as special cases. The formulation also includes new possibilities for considering vertical integrals that are dependent on convective-scale variables, such as the moisture within convection. The generalized convective quasi-equilibrium is defined by a balance between large-scale forcing and convective response for a given vertically-integrated quantity. The latter takes the form of a convolution of a kernel matrix and a mass-flux spectrum, as in the original convective quasi-equilibrium. The kernel reduces to a scalar when either a bulk formulation is adopted, or only large-scale variables are considered within the vertical integral. Various physical implications of the generalized closure are discussed. These include the possibility that precipitation might be considered as a potentially-significant contribution to the large-scale forcing. Two dicta are proposed as guiding physical principles for the specifying a suitable vertically-integrated quantity.

  4. 21 CFR 104.5 - General principles.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false General principles. 104.5 Section 104.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN... product shall bear nutrition labeling in accordance with §§ 101.2 and 101.9 of this chapter and all...

  5. 21 CFR 104.5 - General principles.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false General principles. 104.5 Section 104.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN... product shall bear nutrition labeling in accordance with §§ 101.2 and 101.9 of this chapter and all...

  6. 21 CFR 104.5 - General principles.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false General principles. 104.5 Section 104.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN... product shall bear nutrition labeling in accordance with §§ 101.2 and 101.9 of this chapter and all...

  7. Teaching General Principles and Applications of Dendrogeomorphology.

    ERIC Educational Resources Information Center

    Butler, David R.

    1987-01-01

    Tree-ring analysis in geomorphology can be incorporated into a number of undergraduate methods in order to reconstruct the history of a variety of geomorphic processes. Discusses dendrochronology, general principles of dendrogeomorphology, field sampling methods, laboratory techniques, and examples of applications. (TW)

  8. 5 CFR 551.202 - General principles.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false General principles. 551.202 Section 551.202 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY... preclude exemption under another category. For example, an engineering technician who fails to meet...

  9. 5 CFR 551.202 - General principles.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false General principles. 551.202 Section 551.202 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY... preclude exemption under another category. For example, an engineering technician who fails to meet...

  10. 5 CFR 551.202 - General principles.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false General principles. 551.202 Section 551.202 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY... preclude exemption under another category. For example, an engineering technician who fails to meet...

  11. 5 CFR 551.202 - General principles.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false General principles. 551.202 Section 551.202 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY... preclude exemption under another category. For example, an engineering technician who fails to meet...

  12. 5 CFR 551.202 - General principles.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false General principles. 551.202 Section 551.202 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY... preclude exemption under another category. For example, an engineering technician who fails to meet...

  13. 21 CFR 102.5 - General principles.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false General principles. 102.5 Section 102.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN... words “containing (or contains) _ percent (or %) ___” or “_ percent (or %) ___” with the first...

  14. 18 CFR 358.2 - General principles.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false General principles. 358.2 Section 358.2 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY STANDARDS OF CONDUCT FOR TRANSMISSION PROVIDERS STANDARDS OF CONDUCT § 358.2...

  15. 39 CFR 602.1 - General principles.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Service UNITED STATES POSTAL SERVICE PROCUREMENT SYSTEM FOR THE U.S. POSTAL SERVICE: INTELLECTUAL PROPERTY RIGHTS OTHER THAN PATENTS INTELLECTUAL PROPERTY RIGHTS OTHER THAN PATENTS § 602.1 General principles. It is the policy of the Postal Service to secure full ownership rights for its intellectual...

  16. General Quantum Interference Principle and Duality Computer

    NASA Astrophysics Data System (ADS)

    Long, Gui-Lu

    2006-05-01

    In this article, we propose a general principle of quantum interference for quantum system, and based on this we propose a new type of computing machine, the duality computer, that may outperform in principle both classical computer and the quantum computer. According to the general principle of quantum interference, the very essence of quantum interference is the interference of the sub-waves of the quantum system itself. A quantum system considered here can be any quantum system: a single microscopic particle, a composite quantum system such as an atom or a molecule, or a loose collection of a few quantum objects such as two independent photons. In the duality computer, the wave of the duality computer is split into several sub-waves and they pass through different routes, where different computing gate operations are performed. These sub-waves are then re-combined to interfere to give the computational results. The quantum computer, however, has only used the particle nature of quantum object. In a duality computer, it may be possible to find a marked item from an unsorted database using only a single query, and all NP-complete problems may have polynomial algorithms. Two proof-of-the-principle designs of the duality computer are presented: the giant molecule scheme and the nonlinear quantum optics scheme. We also propose thought experiment to check the related fundamental issues, the measurement efficiency of a partial wave function.

  17. Gravitational tests of the generalized uncertainty principle

    NASA Astrophysics Data System (ADS)

    Scardigli, Fabio; Casadio, Roberto

    2015-09-01

    We compute the corrections to the Schwarzschild metric necessary to reproduce the Hawking temperature derived from a generalized uncertainty principle (GUP), so that the GUP deformation parameter is directly linked to the deformation of the metric. Using this modified Schwarzschild metric, we compute corrections to the standard general relativistic predictions for the light deflection and perihelion precession, both for planets in the solar system and for binary pulsars. This analysis allows us to set bounds for the GUP deformation parameter from well-known astronomical measurements.

  18. Lorentz invariance violation and generalized uncertainty principle

    NASA Astrophysics Data System (ADS)

    Tawfik, Abdel Nasser; Magdy, H.; Ali, A. Farag

    2016-01-01

    There are several theoretical indications that the quantum gravity approaches may have predictions for a minimal measurable length, and a maximal observable momentum and throughout a generalization for Heisenberg uncertainty principle. The generalized uncertainty principle (GUP) is based on a momentum-dependent modification in the standard dispersion relation which is conjectured to violate the principle of Lorentz invariance. From the resulting Hamiltonian, the velocity and time of flight of relativistic distant particles at Planck energy can be derived. A first comparison is made with recent observations for Hubble parameter in redshift-dependence in early-type galaxies. We find that LIV has two types of contributions to the time of flight delay Δ t comparable with that observations. Although the wrong OPERA measurement on faster-than-light muon neutrino anomaly, Δ t, and the relative change in the speed of muon neutrino Δ v in dependence on redshift z turn to be wrong, we utilize its main features to estimate Δ v. Accordingly, the results could not be interpreted as LIV. A third comparison is made with the ultra high-energy cosmic rays (UHECR). It is found that an essential ingredient of the approach combining string theory, loop quantum gravity, black hole physics and doubly spacial relativity and the one assuming a perturbative departure from exact Lorentz invariance. Fixing the sensitivity factor and its energy dependence are essential inputs for a reliable confronting of our calculations to UHECR. The sensitivity factor is related to the special time of flight delay and the time structure of the signal. Furthermore, the upper and lower bounds to the parameter, a that characterizes the generalized uncertainly principle, have to be fixed in related physical systems such as the gamma rays bursts.

  19. Responsible gambling: general principles and minimal requirements.

    PubMed

    Blaszczynski, Alex; Collins, Peter; Fong, Davis; Ladouceur, Robert; Nower, Lia; Shaffer, Howard J; Tavares, Hermano; Venisse, Jean-Luc

    2011-12-01

    Many international jurisdictions have introduced responsible gambling programs. These programs intend to minimize negative consequences of excessive gambling, but vary considerably in their aims, focus, and content. Many responsible gambling programs lack a conceptual framework and, in the absence of empirical data, their components are based only on general considerations and impressions. This paper outlines the consensus viewpoint of an international group of researchers suggesting fundamental responsible gambling principles, roles of key stakeholders, and minimal requirements that stakeholders can use to frame and inform responsible gambling programs across jurisdictions. Such a framework does not purport to offer value statements regarding the legal status of gambling or its expansion. Rather, it proposes gambling-related initiatives aimed at government, industry, and individuals to promote responsible gambling and consumer protection. This paper argues that there is a set of basic principles and minimal requirements that should form the basis for every responsible gambling program. PMID:21359586

  20. A review of the generalized uncertainty principle

    NASA Astrophysics Data System (ADS)

    Nasser Tawfik, Abdel; Magied Diab, Abdel

    2015-12-01

    Based on string theory, black hole physics, doubly special relativity and some ‘thought’ experiments, minimal distance and/or maximum momentum are proposed. As alternatives to the generalized uncertainty principle (GUP), the modified dispersion relation, the space noncommutativity, the Lorentz invariance violation, and the quantum-gravity-induced birefringence effects are summarized. The origin of minimal measurable quantities and the different GUP approaches are reviewed and the corresponding observations are analysed. Bounds on the GUP parameter are discussed and implemented in the understanding of recent PLANCK observations of cosmic inflation. The higher-order GUP approaches predict minimal length uncertainty with and without maximum momenta. Possible arguments against the GUP are discussed; for instance, the concern about its compatibility with the equivalence principles, the universality of gravitational redshift and the free fall and law of reciprocal action are addressed.

  1. A review of the generalized uncertainty principle.

    PubMed

    Tawfik, Abdel Nasser; Diab, Abdel Magied

    2015-12-01

    Based on string theory, black hole physics, doubly special relativity and some 'thought' experiments, minimal distance and/or maximum momentum are proposed. As alternatives to the generalized uncertainty principle (GUP), the modified dispersion relation, the space noncommutativity, the Lorentz invariance violation, and the quantum-gravity-induced birefringence effects are summarized. The origin of minimal measurable quantities and the different GUP approaches are reviewed and the corresponding observations are analysed. Bounds on the GUP parameter are discussed and implemented in the understanding of recent PLANCK observations of cosmic inflation. The higher-order GUP approaches predict minimal length uncertainty with and without maximum momenta. Possible arguments against the GUP are discussed; for instance, the concern about its compatibility with the equivalence principles, the universality of gravitational redshift and the free fall and law of reciprocal action are addressed. PMID:26512022

  2. Sedimentation equilibrium and the generalized Archimedes' principle.

    PubMed

    Parola, Alberto; Buzzaccaro, Stefano; Secchi, Eleonora; Piazza, Roberto

    2013-03-21

    The buoyancy concept is critically re-examined for applications to dispersions of nano-particles, such as colloids, proteins, or macromolecules. It is shown that when the size of the buoyant particle is not too different (say, at most a factor of ten) from the size of the dispersed particles, new intriguing phenomena emerge, leading to the violation of the Archimedes' principle. The resulting buoyancy force depends not only on the volume of the particle and on the mass density of the dispersion, but also on the relative size of the particles, on their geometry, and on the interactions between the buoyant particle and the fluid. Explicit expressions for such a generalized Archimedes' principle are obtained and the results are tested against targeted experiments in colloidal dispersions. PMID:23534662

  3. Dilaton cosmology, noncommutativity, and generalized uncertainty principle

    SciTech Connect

    Vakili, Babak

    2008-02-15

    The effects of noncommutativity and of the existence of a minimal length on the phase space of a dilatonic cosmological model are investigated. The existence of a minimum length results in the generalized uncertainty principle (GUP), which is a deformed Heisenberg algebra between the minisuperspace variables and their momenta operators. I extend these deformed commutating relations to the corresponding deformed Poisson algebra. For an exponential dilaton potential, the exact classical and quantum solutions in the commutative and noncommutative cases, and some approximate analytical solutions in the case of GUP, are presented and compared.

  4. Generalized uncertainty principle: Approaches and applications

    NASA Astrophysics Data System (ADS)

    Tawfik, A.; Diab, A.

    2014-11-01

    In this paper, we review some highlights from the String theory, the black hole physics and the doubly special relativity and some thought experiments which were suggested to probe the shortest distances and/or maximum momentum at the Planck scale. Furthermore, all models developed in order to implement the minimal length scale and/or the maximum momentum in different physical systems are analyzed and compared. They entered the literature as the generalized uncertainty principle (GUP) assuming modified dispersion relation, and therefore are allowed for a wide range of applications in estimating, for example, the inflationary parameters, Lorentz invariance violation, black hole thermodynamics, Saleker-Wigner inequalities, entropic nature of gravitational laws, Friedmann equations, minimal time measurement and thermodynamics of the high-energy collisions. One of the higher-order GUP approaches gives predictions for the minimal length uncertainty. A second one predicts a maximum momentum and a minimal length uncertainty, simultaneously. An extensive comparison between the different GUP approaches is summarized. We also discuss the GUP impacts on the equivalence principles including the universality of the gravitational redshift and the free fall and law of reciprocal action and on the kinetic energy of composite system. The existence of a minimal length and a maximum momentum accuracy is preferred by various physical observations. The concern about the compatibility with the equivalence principles, the universality of gravitational redshift and the free fall and law of reciprocal action should be addressed. We conclude that the value of the GUP parameters remain a puzzle to be verified.

  5. Space flight operations communications phraseology and techniques

    NASA Technical Reports Server (NTRS)

    Noneman, S. R.

    1986-01-01

    Communications are a critical link in space flight operations. Specific communications phraseology and techniques have been developed to allow rapid and clear transfer of information. Communications will be clear and brief through the use of procedural words and phrases. Communications protocols standardize the required information transferred. The voicing of letters and numbers is discussed. The protocols used in air-to-ground communications are given. A glossary of communications terminology is presented in the appendix.

  6. [General principles in psychotherapy of personality disorders].

    PubMed

    Bohus, Martin; Doering, Stephan; Schmitz, Bernt; Herpertz, Sabine C

    2009-01-01

    S2 guidelines for diagnostics and treatment of personality disorders have been developed under the umbrella of the AWMF Germany. Following the current trend to manualized axis I treatment programs, within the recent years specific treatment programs have also been developed for some personality disorders like borderline personality disorder, antisocial personality disorder and avoidant personality disorder. The superiority of these treatment programs compared to unspecific approaches is meanwhile proven on a robust empirical basis. The S2 guidelines task force extracted the principles of these manualized treatment programs to provide the framework for a general clinically oriented concept for the treatment of personality disorders. The intention was to develop a concept which gets beyond the school oriented therapeutic approaches in order to provide the platform for further developments of general and specific treatments for personality disorders. PMID:19350475

  7. 14 CFR Sec. 2-1 - Generally accepted accounting principles.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Generally accepted accounting principles... AIR CARRIERS General Accounting Provisions Sec. 2-1 Generally accepted accounting principles. (a) The accounting provisions contained in this part are based on generally accepted accounting principles...

  8. 14 CFR Sec. 2-1 - Generally accepted accounting principles.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Generally accepted accounting principles... AIR CARRIERS General Accounting Provisions Sec. 2-1 Generally accepted accounting principles. (a) The accounting provisions contained in this part are based on generally accepted accounting principles...

  9. 34 CFR 76.530 - General cost principles.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Be Met by the State and Its Subgrantees? Allowable Costs § 76.530 General cost principles. Both 34 CFR 74.27 and 34 CFR 80.22 reference the general cost principles that apply to grants, subgrants...

  10. 34 CFR 76.530 - General cost principles.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Be Met by the State and Its Subgrantees? Allowable Costs § 76.530 General cost principles. Both 34 CFR 74.27 and 34 CFR 80.22 reference the general cost principles that apply to grants, subgrants...

  11. 34 CFR 76.530 - General cost principles.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Be Met by the State and Its Subgrantees? Allowable Costs § 76.530 General cost principles. Both 34 CFR 74.27 and 34 CFR 80.22 reference the general cost principles that apply to grants, subgrants...

  12. 34 CFR 76.530 - General cost principles.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Be Met by the State and Its Subgrantees? Allowable Costs § 76.530 General cost principles. Both 34 CFR 74.27 and 34 CFR 80.22 reference the general cost principles that apply to grants, subgrants...

  13. Rowlands' Duality Principle: A Generalization of Noether's Theorem?

    NASA Astrophysics Data System (ADS)

    Karam, Sabah E.

    This paper will examine a physical principle that has been used in making valid predictions and generalizes established conservation laws. In a previous paper it was shown how Rowlands' zero-totality condition could be viewed as a generalization of Newton's third law of motion. In this paper it will be argued that Rowlands' Duality Principle is a generalization of Noether's Theorem and that the two principles taken together are truly foundational principles that have tamed Metaphysics.

  14. Action principle combining electromagnetism and general relativity

    SciTech Connect

    Moyer, H.G.

    1987-03-01

    The stationary action problem for a single, classical, point particle in external gravitational and electromagnetic fields is written in optimal control format. The relativistic interval is the independent variable and time, space, and action are the five dependent variables. A general metric is used for the space-time manifold so that the equations are manifestly covariant. The form of the system equations guarantees that the particle moves with unit speed with respect to interval. The Lagrangian is a function of the metric tensor and the electromagnetic four-potential, but not of particle parameters such as electric charge q and mass m. The Hamiltonian is not identically zero, unlike those derived in many earlier analyses. A constant of the motion is found that is identified with q/mc/sup 2/. An explanation is presented for the classical inequality mgreater than or equal to0. The trajectories can reduce to geodesics and even further to those governed by Fermat's principle of stationary time.

  15. Principle of least action; some possible generalizations

    SciTech Connect

    Broucke, R.

    1982-08-01

    In this article we draw the attention to an important variational principle in dynamics: the Maupertuis-Jacobi Least Action Principle (MJLAP). This principle compares varied paths with the same energy h. We give two new proofs of the MJLAP (Sections 3 and 8) as well as a new unified variational principle which contains both Hamilton's Principle (HP) and the MJLAP as particular cases (Sections 4 and 9). The article also shows several new methods for the construction of a Lagrangian for a conservative dynamical system. As an example, we illustrate the theory with the classical Harmonic Oscillator Problem (Section 10). Our method is based on the theory of changes of independent variables in a dynamical system. It indirectly shows how a change of independent variable affects the self-adjointness of a dynamical system (Sections 5, 6, 7). Our new Lagrangians contain an arbitrary constant ..cap alpha.., whose meaning needs to be studied, eventually in relation to the concepts of quantification or gauge transformations. The two important values of the constant ..cap alpha.. are 1 (Hamilton's principle) and 1/2 (Maupertuis-Jacobi Least Action Principle).

  16. Incorporation of generalized uncertainty principle into Lifshitz field theories

    SciTech Connect

    Faizal, Mir; Majumder, Barun

    2015-06-15

    In this paper, we will incorporate the generalized uncertainty principle into field theories with Lifshitz scaling. We will first construct both bosonic and fermionic theories with Lifshitz scaling based on generalized uncertainty principle. After that we will incorporate the generalized uncertainty principle into a non-abelian gauge theory with Lifshitz scaling. We will observe that even though the action for this theory is non-local, it is invariant under local gauge transformations. We will also perform the stochastic quantization of this Lifshitz fermionic theory based generalized uncertainty principle.

  17. A General Conditional Large Deviation Principle

    NASA Astrophysics Data System (ADS)

    La Cour, Brian R.; Schieve, William C.

    2015-10-01

    Given a sequence of Borel probability measures on a Hausdorff space which satisfy a large deviation principle (LDP), we consider the corresponding sequence of measures formed by conditioning on a set B. If the large deviation rate function I is good and effectively continuous, and the conditioning set has the property that (1) and (2) for all , then the sequence of conditional measures satisfies a LDP with the good, effectively continuous rate function , where if and otherwise.

  18. 23 CFR 627.5 - General principles and procedures.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false General principles and procedures. 627.5 Section 627.5 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS VALUE ENGINEERING § 627.5 General principles and procedures. (a) State VE programs. State transportation departments must establish programs...

  19. 32 CFR 1633.7 - General principles of classification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false General principles of classification. 1633.7 Section 1633.7 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM ADMINISTRATION OF CLASSIFICATION § 1633.7 General principles of classification. (a) Each classified registrant...

  20. Oncologic reconstruction: General principles and techniques.

    PubMed

    Ho, Adelyn L; Lyonel Carre, Antoine; Patel, Ketan M

    2016-06-01

    Halsted's principle of radical mastectomy influenced cancer treatment for decades. Randomized controlled trials resulted in a paradigm shift to less radical surgery and the use of adjuvant therapies. Oncologic reconstruction performed by plastic surgeons has evolved, ranging from skin grafts and local flaps for smaller defects to pedicled flaps and free flaps for larger and more complex defects. Immediate reconstruction facilitates resection is oncologically safe and contributes to meaningful improvements in quality of life. J. Surg. Oncol. 2016;113:852-864. © 2016 Wiley Periodicals, Inc. PMID:26939879

  1. Generalization of the ERIT principle and method.

    SciTech Connect

    Ruggiero,A.G.

    2007-11-04

    The paper describes the generalization of the method to produce secondary particles with a low-energy and low-intensity primary beam circulating in a Storage Ring with the Emittance-Recovery by Internal-Target (ERIT).

  2. Generalization of the ERIT Principle and Method

    SciTech Connect

    Ruggiero,A.

    2008-02-01

    The paper describes the generalization of the method to produce secondary particles with a low-energy and low-intensity primary beam circulating in a Storage Ring with the Emittance-Recovery by Internal-Target (ERIT).

  3. 21 CFR 101.13 - general principles.

    Code of Federal Regulations, 2011 CFR

    1996-04-01

    ... content claims FOOD AND DRUGS FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES--CONTINUED FOOD FOR HUMAN CONSUMPTION FOOD LABELING General Provisions Sec. 101.13 Nutrient content claims... supplements). (b) A claim that expressly or implicitly characterizes the level of a nutrient (nutrient...

  4. 21 CFR 502.5 - General principles.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS COMMON OR USUAL NAMES FOR NONSTANDARDIZED ANIMAL FOODS § 502.5 General..., what it is in a way that distinguishes it from different foods. (b) The common or usual name of a...

  5. 43 CFR 24.3 - General jurisdictional principles.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... enactment of Federal fish and wildlife conservation statutes has generally been associated with the... FISH AND WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.3 General jurisdictional principles. (a) In general the States possess broad trustee and police powers over fish and wildlife within their...

  6. 43 CFR 24.3 - General jurisdictional principles.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... enactment of Federal fish and wildlife conservation statutes has generally been associated with the... FISH AND WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.3 General jurisdictional principles. (a) In general the States possess broad trustee and police powers over fish and wildlife within their...

  7. 43 CFR 24.3 - General jurisdictional principles.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... enactment of Federal fish and wildlife conservation statutes has generally been associated with the... FISH AND WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.3 General jurisdictional principles. (a) In general the States possess broad trustee and police powers over fish and wildlife within their...

  8. 43 CFR 24.3 - General jurisdictional principles.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... enactment of Federal fish and wildlife conservation statutes has generally been associated with the... FISH AND WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.3 General jurisdictional principles. (a) In general the States possess broad trustee and police powers over fish and wildlife within their...

  9. Generalized Principles of Unchanging Total Concentration

    PubMed Central

    Kottke, Peter A.; Fedorov, Andrei G.

    2008-01-01

    We consider transport of multiple reacting species under the continuum assumption in situations such as those that frequently arise in electroanalytical chemistry. Under certain limitations, it has been shown that the total species concentration (as defined by Oldham and Feldberg1) of such a system is uniform and constant. In this work, we extend the limits of the previous analysis to enable greater applicability. This is accomplished by using either of two new dependent variables, which are generalizations of the concept of total concentration. Then conditions are determined under which the dependent variable will be uniform, and constant in time. From a practical viewpoint, the described formalism allows one to simplify the multispecies transport problem formulation by eliminating one equation from the system of governing equations. PMID:16853140

  10. The Generalized Uncertainty Principle and the Friedmann equations

    NASA Astrophysics Data System (ADS)

    Majumder, Barun

    2011-12-01

    The Generalized Uncertainty Principle (or GUP) affects the dynamics in Plank scale. So the known equations of physics are expected to get modified at that very high energy regime. Very recently authors in Ali et al. (Phys. Lett. B 678:497, 2009) proposed a new Generalized Uncertainty Principle (or GUP) with a linear term in Plank length. In this article, the proposed GUP is expressed in a more general form and the effect is studied for the modification of the Friedmann equations of the FRW universe. In the midway the known entropy-area relation get some new correction terms, the leading order term being proportional to sqrt{Area}.

  11. 29 CFR 780.138 - Application of the general principles.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Application of the general principles. 780.138 Section 780.138 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF...

  12. Gauge theories under incorporation of a generalized uncertainty principle

    SciTech Connect

    Kober, Martin

    2010-10-15

    There is considered an extension of gauge theories according to the assumption of a generalized uncertainty principle which implies a minimal length scale. A modification of the usual uncertainty principle implies an extended shape of matter field equations like the Dirac equation. If there is postulated invariance of such a generalized field equation under local gauge transformations, the usual covariant derivative containing the gauge potential has to be replaced by a generalized covariant derivative. This leads to a generalized interaction between the matter field and the gauge field as well as to an additional self-interaction of the gauge field. Since the existence of a minimal length scale seems to be a necessary assumption of any consistent quantum theory of gravity, the gauge principle is a constitutive ingredient of the standard model, and even gravity can be described as gauge theory of local translations or Lorentz transformations, the presented extension of gauge theories appears as a very important consideration.

  13. An Investigation of Crosslinguistic Transfer in EFL Learners' Phraseology

    ERIC Educational Resources Information Center

    Liao, Ern-Huei

    2010-01-01

    The problem. The purpose of this study is to investigate positive and negative cross-linguistic transfer on EFL learners' phraseological competence in collocations and its relationship to learners' linguistic proficiency. Method. A quantitative study was conducted. Two instruments, multiple choice test and grammaticality judgment test, were…

  14. A generalization of Fermat's principle for classical and quantum systems

    NASA Astrophysics Data System (ADS)

    Elsayed, Tarek A.

    2014-09-01

    The analogy between dynamics and optics had a great influence on the development of the foundations of classical and quantum mechanics. We take this analogy one step further and investigate the validity of Fermat's principle in many-dimensional spaces describing dynamical systems (i.e., the quantum Hilbert space and the classical phase and configuration space). We propose that if the notion of a metric distance is well defined in that space and the velocity of the representative point of the system is an invariant of motion, then a generalized version of Fermat's principle will hold. We substantiate this conjecture for time-independent quantum systems and for a classical system consisting of coupled harmonic oscillators. An exception to this principle is the configuration space of a charged particle in a constant magnetic field; in this case the principle is valid in a frame rotating by half the Larmor frequency, not the stationary lab frame.

  15. Generalized Franck-Condon principle for resonant photoemission

    NASA Astrophysics Data System (ADS)

    Sałek, Paweł; Gel'mukhanov, Faris; Ågren, Hans; Björneholm, Olle; Svensson, Svante

    1999-10-01

    A generalized Franck-Condon (GFC) principle for resonant x-ray Raman scattering and for resonant photoemission in particular is derived and numerically investigated. The GFC amplitudes differ from ordinary FC amplitudes by the presence of photon and photoelectron phase factors which describe the coupling-or interference-of the x-ray photons or Auger electrons with the nuclear motion. With the GFC amplitudes, a Kramers-Heisenberg relation is obtained for vibronic transitions that corrects the so-called lifetime-vibrational interference formula. For resonant photoemission in the soft-x-ray region involving typical bound potential surfaces, the generalization gives a contribution to the FC factors that can amount to 20%. For core excitation above the dissociation threshold, the GFC principle relates to Doppler effects on the ejected photoelectron both for the so-called ``molecular'' and ``atomic'' bands. The role of the GFC principle in direct photoionization is briefly discussed.

  16. “Stringy” coherent states inspired by generalized uncertainty principle

    NASA Astrophysics Data System (ADS)

    Ghosh, Subir; Roy, Pinaki

    2012-05-01

    Coherent States with Fractional Revival property, that explicitly satisfy the Generalized Uncertainty Principle (GUP), have been constructed in the context of Generalized Harmonic Oscillator. The existence of such states is essential in motivating the GUP based phenomenological results present in the literature which otherwise would be of purely academic interest. The effective phase space is Non-Canonical (or Non-Commutative in popular terminology). Our results have a smooth commutative limit, equivalent to Heisenberg Uncertainty Principle. The Fractional Revival time analysis yields an independent bound on the GUP parameter. Using this and similar bounds obtained here, we derive the largest possible value of the (GUP induced) minimum length scale. Mandel parameter analysis shows that the statistics is Sub-Poissonian. Correspondence Principle is deformed in an interesting way. Our computational scheme is very simple as it requires only first order corrected energy values and undeformed basis states.

  17. 2 CFR 200.49 - Generally Accepted Accounting Principles (GAAP).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Generally Accepted Accounting Principles (GAAP). 200.49 Section 200.49 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GUIDANCE Reserved UNIFORM ADMINISTRATIVE...

  18. 23 CFR 627.5 - General principles and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... project meeting the project criteria in 23 CFR 627.1(a), the STDs shall fulfill the value engineering... Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS VALUE ENGINEERING § 627.5 General principles and procedures. (a) State VE programs. State...

  19. Preoperative Medical Evaluation: Part 1: General Principles and Cardiovascular Considerations

    PubMed Central

    Becker, Daniel E

    2009-01-01

    A thorough assessment of a patient's medical status is standard practice when dental care is provided. Although this is true for procedures performed under local anesthesia alone, the information gathered may be viewed somewhat differently if the dentist is planning to use sedation or general anesthesia as an adjunct to dental treatment. This article is the first of a 2-part sequence and will address general principles and cardiovascular considerations. A second article will address pulmonary, metabolic, and miscellaneous disorders. PMID:19769423

  20. Quaternionic quantization principle in general relativity and supergravity

    NASA Astrophysics Data System (ADS)

    Kober, Martin

    2016-01-01

    A generalized quantization principle is considered, which incorporates nontrivial commutation relations of the components of the variables of the quantized theory with the components of the corresponding canonical conjugated momenta referring to other space-time directions. The corresponding commutation relations are formulated by using quaternions. At the beginning, this extended quantization concept is applied to the variables of quantum mechanics. The resulting Dirac equation and the corresponding generalized expression for plane waves are formulated and some consequences for quantum field theory are considered. Later, the quaternionic quantization principle is transferred to canonical quantum gravity. Within quantum geometrodynamics as well as the Ashtekar formalism, the generalized algebraic properties of the operators describing the gravitational observables and the corresponding quantum constraints implied by the generalized representations of these operators are determined. The generalized algebra also induces commutation relations of the several components of the quantized variables with each other. Finally, the quaternionic quantization procedure is also transferred to 𝒩 = 1 supergravity. Accordingly, the quantization principle has to be generalized to be compatible with Dirac brackets, which appear in canonical quantum supergravity.

  1. Some General Principles in Cryogenic Design, Implementation, and Testing

    NASA Technical Reports Server (NTRS)

    Dipirro, Michael James

    2015-01-01

    Brief Course Description: In 2 hours only the most basic principles of cryogenics can be presented. I will concentrate on the differences between a room temperature thermal analysis and cryogenic thermal analysis, namely temperature dependent properties. I will talk about practical materials for thermal contact and isolation. I will finish by describing the verification process and instrumentation used that is unique to cryogenic (in general less than 100K) systems.

  2. Quantum black hole in the generalized uncertainty principle framework

    SciTech Connect

    Bina, A.; Moslehi, A.; Jalalzadeh, S.

    2010-01-15

    In this paper we study the effects of the generalized uncertainty principle (GUP) on canonical quantum gravity of black holes. Through the use of modified partition function that involves the effects of the GUP, we obtain the thermodynamical properties of the Schwarzschild black hole. We also calculate the Hawking temperature and entropy for the modification of the Schwarzschild black hole in the presence of the GUP.

  3. Generalized uncertainty principle in Bianchi type I quantum cosmology

    NASA Astrophysics Data System (ADS)

    Vakili, B.; Sepangi, H. R.

    2007-07-01

    We study a quantum Bianchi type I model in which the dynamical variables of the corresponding minisuperspace obey the generalized Heisenberg algebra. Such a generalized uncertainty principle has its origin in the existence of a minimal length suggested by quantum gravity and sting theory. We present approximate analytical solutions to the corresponding Wheeler DeWitt equation in the limit where the scale factor of the universe is small and compare the results with the standard commutative and noncommutative quantum cosmology. Similarities and differences of these solutions are also discussed.

  4. Constraining the generalized uncertainty principle with cold atoms

    NASA Astrophysics Data System (ADS)

    Gao, Dongfeng; Zhan, Mingsheng

    2016-07-01

    Various theories of quantum gravity predict the existence of a minimum length scale, which implies the Planck-scale modifications of the Heisenberg uncertainty principle to a so-called generalized uncertainty principle (GUP). Previous studies of the GUP focused on its implications for high-energy physics, cosmology, and astrophysics. Here the application of the GUP to low-energy quantum systems, and particularly cold atoms, is studied. Results from the 87Rb atom recoil experiment are used to set upper bounds on parameters in three different GUP proposals. A 1014-level bound on the Ali-Das-Vagenas proposal is found, which is the second best bound so far. A 1026-level bound on Maggiore's proposal is obtained, which turns out to be the best available bound on it.

  5. Sub-Planckian black holes and the Generalized Uncertainty Principle

    NASA Astrophysics Data System (ADS)

    Carr, Bernard; Mureika, Jonas; Nicolini, Piero

    2015-07-01

    The Black Hole Uncertainty Principle correspondence suggests that there could exist black holes with mass beneath the Planck scale but radius of order the Compton scale rather than Schwarzschild scale. We present a modified, self-dual Schwarzschild-like metric that reproduces desirable aspects of a variety of disparate models in the sub-Planckian limit, while remaining Schwarzschild in the large mass limit. The self-dual nature of this solution under M ↔ M -1 naturally implies a Generalized Uncertainty Principle with the linear form . We also demonstrate a natural dimensional reduction feature, in that the gravitational radius and thermodynamics of sub-Planckian objects resemble that of (1 + 1)-D gravity. The temperature of sub-Planckian black holes scales as M rather than M -1 but the evaporation of those smaller than 10-36 g is suppressed by the cosmic background radiation. This suggests that relics of this mass could provide the dark matter.

  6. A South African perspective on children's rights: general principles.

    PubMed

    Klinck, M E; Iuris, B; Louw, D A; Peens, B J

    2000-01-01

    South Africa has made rapid progress in the field of human and especially children's rights. This is in sharp contrast with it's apartheid history where even the basic principles of human rights were negated. In this article an overview will be given of the general principles on which the realization of children's rights in South Africa are based. More specifically information on the population, economic status, political climate and recent developments in this field is presented. This is followed by a discussion on the social-economic nature of children's rights, the courts as enforcement mechanisms, and the contents of the best interest standard as described both in convention on the rights of the child and the South African Constitution. PMID:10876302

  7. Minisuperspace dynamics in a generalized uncertainty principle framework

    SciTech Connect

    Battisti, Marco Valerio; Montani, Giovanni

    2008-01-03

    The minisuperspace dynamics of the Friedmann-Robertson-Walker (FRW) and of the Taub Universes in the context of a Generalized Uncertainty Principle is analyzed in detail. In particular, the motion of the wave packets is investigated and, in both the models, the classical singularity appear to be probabilistic suppressed. Moreover, the FRW wave packets approach the Planckian region in a stationary way and no evidences for a Big-Bounce, as predicted in Loop Quantum Cosmology, appear. On the other hand, the Taub wave packets provide the right behavior in predicting an isotropic Universe.

  8. General cognitive principles for learning structure in time and space.

    PubMed

    Goldstein, Michael H; Waterfall, Heidi R; Lotem, Arnon; Halpern, Joseph Y; Schwade, Jennifer A; Onnis, Luca; Edelman, Shimon

    2010-06-01

    How are hierarchically structured sequences of objects, events or actions learned from experience and represented in the brain? When several streams of regularities present themselves, which will be learned and which ignored? Can statistical regularities take effect on their own, or are additional factors such as behavioral outcomes expected to influence statistical learning? Answers to these questions are starting to emerge through a convergence of findings from naturalistic observations, behavioral experiments, neurobiological studies, and computational analyses and simulations. We propose that a small set of principles are at work in every situation that involves learning of structure from patterns of experience and outline a general framework that accounts for such learning. PMID:20395164

  9. Factorization in the quantum mechanics with the generalized uncertainty principle

    NASA Astrophysics Data System (ADS)

    Chung, Won Sang

    2015-07-01

    In this paper, we discuss the quantum mechanics with the generalized uncertainty principle (GUP) where the commutation relation is given by [x̂,p̂] = iℏ(1 + αp̂ + βp̂2). For this algebra, we obtain the eigenfunction of the momentum operator. We also study the GUP corrected quantum particle in a box. Finally, we apply the factorization method to the harmonic oscillator in the presence of a minimal observable length and obtain the energy eigenvalues by applying the perturbation method.

  10. A general maximum entropy framework for thermodynamic variational principles

    SciTech Connect

    Dewar, Roderick C.

    2014-12-05

    Minimum free energy principles are familiar in equilibrium thermodynamics, as expressions of the second law. They also appear in statistical mechanics as variational approximation schemes, such as the mean-field and steepest-descent approximations. These well-known minimum free energy principles are here unified and extended to any system analyzable by MaxEnt, including non-equilibrium systems. The MaxEnt Lagrangian associated with a generic MaxEnt distribution p defines a generalized potential Ψ for an arbitrary probability distribution p-hat, such that Ψ is a minimum at (p-hat) = p. Minimization of Ψ with respect to p-hat thus constitutes a generic variational principle, and is equivalent to minimizing the Kullback-Leibler divergence between p-hat and p. Illustrative examples of min–Ψ are given for equilibrium and non-equilibrium systems. An interpretation of changes in Ψ is given in terms of the second law, although min–Ψ itself is an intrinsic variational property of MaxEnt that is distinct from the second law.

  11. Generalized Uncertainty Principle and Thermostatistics: A Semiclassical Approach

    NASA Astrophysics Data System (ADS)

    Abbasiyan-Motlaq, Mohammad; Pedram, Pouria

    2016-04-01

    We present an exact treatment of the thermodynamics of physical systems in the framework of the generalized uncertainty principle (GUP). Our purpose is to study and compare the consequences of two GUPs that one implies a minimal length while the other predicts a minimal length and a maximal momentum. Using a semiclassical method, we exactly calculate the modified internal energies and heat capacities in the presence of generalized commutation relations. We show that the total shift in these quantities only depends on the deformed algebra not on the system under study. Finally, the modified internal energy for an specific physical system such as ideal gas is obtained in the framework of two different GUPs.

  12. An interesting consequence of the general principle of relativity

    NASA Astrophysics Data System (ADS)

    Grøn, Øyvind; Jemterud, Torkild

    2016-04-01

    We show that Einstein's general theory of relativity, together with the assumption that the principle of relativity encompasses rotational motion, predicts that in a flat Friedmann-Lemaitre-Robertson-Walker (FLRW) universe model with dust and Lorentz Invariant Vacuum Energy (LIVE), the density parameter of vacuum energy must have the value Ω_{Λ 0}=0.737. The physical mechanism connecting the relativity of rotational motion with the energy density of dark energy is the inertial dragging effect. The predicted value is necessary in order to have perfect inertial dragging, which is required for rotational motion to be relative. If one accepts that due to the impossibility of defining motion for a single particle in an otherwise empty universe, the universe must be constructed so that all types of motion are relative, then this solves the so-called cosmological constant problem.

  13. Entropy principle, non-regular processes, and generalized exploitation procedures

    NASA Astrophysics Data System (ADS)

    Triani, V.; Cimmelli, V. A.

    2012-06-01

    The classical Coleman-Noll approach to the exploitation of the entropy principle regards the classical balances of mass, linear and angular momentum and energy as differential constraints for the entropy inequality, and presupposes that the second law of thermodynamics is a restriction on the constitutive equations describing the material properties [B. D. Coleman and W. Noll, "The thermodynamics of elastic materials with heat conduction and viscosity," Arch. Rational Mech. Anal. 13, 167-178 (1963), 10.1007/BF01262690]. In 1996, Muschik and Ehrentraut proved that this presupposition may be confirmed by a rigorous proof, provided that an amendment to the classical second law of thermodynamics, which asserts that, except in equilibria, reversible process directions in state space do not exist, is postulated ["An amendment to the second law," J. Non-Equilib. Thermodyn. 21, 175-192 (1996), 10.1515/jnet.1996.21.2.175]. In their paper, the authors considered regular processes only. In a recent article [V. Triani and V. A. Cimmelli, "Interpretation of second law of thermodynamics in the presence of interfaces," Continuum. Mech. Thermodyn. 24, 165-174 (2012), 10.1007/s00161-011-0231-8], we proved that the result above remains valid in the presence of interfaces across which the unknown fields suffer jump discontinuities. Here, we show that the same conclusions achieved by Muschik and Ehrentraut and Triani and Cimmelli hold when the classical Coleman-Noll and Liu ["Method of Lagrange multipliers for exploitation of the entropy principle," Arch. Rational Mech. Anal. 46, 131-148 (1972), 10.1007/BF00250688] procedures for the exploitation of the second law, are generalized by considering also the gradients of the fundamental balance equations as constraints for the entropy inequality.

  14. General principles and stages of optimal AFCS design

    NASA Astrophysics Data System (ADS)

    Platonov, A.; Zaitsev, Ie.

    2014-11-01

    The goal of the paper is a discussion of general principle and stages of the optimal analog feedback communication systems (AFCS) design. Previous research devoted to the analysis of particularities of AFCS functioning gave necessary analytical basis for transition to practical design of optimal AFCS. This is new class of communication systems (CS) transmitting the signals, under given bit error rate (BER), with bit rate equal to the capacity of the forward channel and power-bandwidth efficiency attaining the theoretical limit. In the paper, we describe the ordered sequence of the stages of transition from the abstract results to designing of the pre-commercial versions of optimal AFCS considering them as the basic communication link "sensor node (SN)" - "base station" (BS) of the wireless sensor network (WSN). We also show that verified theoretical results enable analytically argued decision making at different stages of designing of the high quality and energy efficient WSN communication links. This facilitates optimisation of the project works schedule, distribution of the tasks and resources for their realization, reduce the time and cost of design.

  15. Modeling of space environment impact on nanostructured materials. General principles

    NASA Astrophysics Data System (ADS)

    Voronina, Ekaterina; Novikov, Lev

    2016-07-01

    In accordance with the resolution of ISO TC20/SC14 WG4/WG6 joint meeting, Technical Specification (TS) 'Modeling of space environment impact on nanostructured materials. General principles' which describes computer simulation methods of space environment impact on nanostructured materials is being prepared. Nanomaterials surpass traditional materials for space applications in many aspects due to their unique properties associated with nanoscale size of their constituents. This superiority in mechanical, thermal, electrical and optical properties will evidently inspire a wide range of applications in the next generation spacecraft intended for the long-term (~15-20 years) operation in near-Earth orbits and the automatic and manned interplanetary missions. Currently, ISO activity on developing standards concerning different issues of nanomaterials manufacturing and applications is high enough. Most such standards are related to production and characterization of nanostructures, however there is no ISO documents concerning nanomaterials behavior in different environmental conditions, including the space environment. The given TS deals with the peculiarities of the space environment impact on nanostructured materials (i.e. materials with structured objects which size in at least one dimension lies within 1-100 nm). The basic purpose of the document is the general description of the methodology of applying computer simulation methods which relate to different space and time scale to modeling processes occurring in nanostructured materials under the space environment impact. This document will emphasize the necessity of applying multiscale simulation approach and present the recommendations for the choice of the most appropriate methods (or a group of methods) for computer modeling of various processes that can occur in nanostructured materials under the influence of different space environment components. In addition, TS includes the description of possible

  16. Training the endoscopy trainer: From general principles to specific concepts

    PubMed Central

    Coderre, Sylvain; Anderson, John; Rostom, Alaa; McLaughlin, Kevin

    2010-01-01

    Endoscopy instruction has progressed a great deal in recent years, evolving from the age-old dictum of ‘see one, do one’ to the current skillful application of sound educational principles. Some of these educational principles are generic and applicable to the teaching of any content at all levels, while others are quite specific to technical skills training. The present review summarizes these important principles under the following headings: creating a learner-centred curriculum; delivering an achievable learning task; and moving from theory to practice. The present article challenges national gastroenterology organizations to embrace these concepts in structured, outcome-based educational programs. PMID:21165376

  17. 12 CFR 621.3 - Application of generally accepted accounting principles.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Application of generally accepted accounting principles. 621.3 Section 621.3 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ACCOUNTING AND REPORTING REQUIREMENTS General Rules § 621.3 Application of generally accepted accounting principles. Each institution shall: (a) Prepare...

  18. Proceedings from the General Education Strand. Guiding Principles for Communication General Education [and] Principles of General Education: A Communication Perspective [and] Administrative Perspectives on Communication in General Education: Best Practices. NCA 2001 Summer Conference: Engaging 21st Century Communication Students.

    ERIC Educational Resources Information Center

    National Communication Association, Annandale, VA.

    This Proceedings from the NCA 2001 Summer Conference deals with the General Education Strand. This strand explored five major issues in establishing and maintaining oral communication as a vital general education component. The five issues covered in the strand were: (1) principles of general education; (2) communication as general education and…

  19. General rule for boundary conditions from the action principle

    NASA Astrophysics Data System (ADS)

    Steiner, Roee

    2016-03-01

    We construct models where initial and boundary conditions can be found from the fundamental rules of physics, without the need to assume them, they will be derived from the action principle. Those constraints are established from physical viewpoint, and it is not in the form of Lagrange multipliers. We show some examples from the past and some new examples that can be useful, where constraint can be obtained from the action principle. Those actions represent physical models. We show that it is possible to use our rule to get those constraints directly.

  20. Thermodynamics of Black Holes and the Symmetric Generalized Uncertainty Principle

    NASA Astrophysics Data System (ADS)

    Dutta, Abhijit; Gangopadhyay, Sunandan

    2016-06-01

    In this paper, we have investigated the thermodynamics of Schwarzschild and Reissner-Nordström black holes using the symmetric generalised uncertainty principle which contains correction terms involving momentum and position uncertainty. The mass-temperature relationship and the heat capacity for these black holes have been computed using which the critical and remnant masses have been obtained. The entropy is found to satisfy the area law upto leading order logarithmic corrections and corrections of the form A 2 (which is a new finding in this paper) from the symmetric generalised uncertainty principle.

  1. Path Integral for Dirac oscillator with generalized uncertainty principle

    SciTech Connect

    Benzair, H.; Boudjedaa, T.; Merad, M.

    2012-12-15

    The propagator for Dirac oscillator in (1+1) dimension, with deformed commutation relation of the Heisenberg principle, is calculated using path integral in quadri-momentum representation. As the mass is related to momentum, we then adapt the space-time transformation method to evaluate quantum corrections and this latter is dependent from the point discretization interval.

  2. 2 CFR Appendix A to Part 230 - General Principles

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET CIRCULARS AND GUIDANCE Reserved COST PRINCIPLES FOR... allocable to a particular cost objective, such as a grant, contract, project, service, or other activity, in..., project, service, or other direct activity of an organization. However, a cost may not be assigned to...

  3. Use of Alumenontos to Introduce General Paleontologic and Biostratigraphic Principles.

    ERIC Educational Resources Information Center

    Hageman, Steven James

    1989-01-01

    Describes exercises in which tabs from aluminum beverage cans are used to introduce principles of classification, biostratigraphy, and evolution. Provides diagrams which represent dorsal and ventral views of species and a table which graphs units of time in relation to species duration. (RT)

  4. Principle of reciprocity solves the most important problems in bioimpedance and in general in bioelectromagnetism

    NASA Astrophysics Data System (ADS)

    Malmivuo, Jaakko

    2010-04-01

    Though the principle of reciprocity was invented by Hermann von Helmholtz already over 150 years ago, and though it is a very powerful tool in solving various important problems in bioelectromagnetism, it is not generally used. In impedance tomography the measurement sensitivity distribution has generally been misunderstood. This can be easily demonstrated with the principle of reciprocity. Some other applications of the principle of reciprocity are also discussed.

  5. 43 CFR 419.3 - What general principles govern implementation of the TROA?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false What general principles govern implementation of the TROA? 419.3 Section 419.3 Public Lands: Interior Regulations Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR TRUCKEE RIVER OPERATING AGREEMENT § 419.3 What general principles govern implementation of the...

  6. 12 CFR 621.3 - Application of generally accepted accounting principles.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... management and the Farm Credit Administration, in accordance with generally accepted accounting principles... 12 Banks and Banking 7 2014-01-01 2014-01-01 false Application of generally accepted accounting principles. 621.3 Section 621.3 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM...

  7. 12 CFR 621.3 - Application of generally accepted accounting principles.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... management and the Farm Credit Administration, in accordance with generally accepted accounting principles... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Application of generally accepted accounting principles. 621.3 Section 621.3 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM...

  8. 12 CFR 621.3 - Application of generally accepted accounting principles.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... management and the Farm Credit Administration, in accordance with generally accepted accounting principles... 12 Banks and Banking 7 2012-01-01 2012-01-01 false Application of generally accepted accounting principles. 621.3 Section 621.3 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM...

  9. 12 CFR 621.3 - Application of generally accepted accounting principles.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... management and the Farm Credit Administration, in accordance with generally accepted accounting principles... 12 Banks and Banking 7 2013-01-01 2013-01-01 false Application of generally accepted accounting principles. 621.3 Section 621.3 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM...

  10. Supersymmetry breaking as a new source for the generalized uncertainty principle

    NASA Astrophysics Data System (ADS)

    Faizal, Mir

    2016-06-01

    In this letter, we will demonstrate that the breaking of supersymmetry by a non-anticommutative deformation can be used to generate the generalized uncertainty principle. We will analyze the physical reasons for this observation, in the framework of string theory. We also discuss the relation between the generalized uncertainty principle and the Lee-Wick field theories.

  11. 26 CFR 1.338-1 - General principles; status of old target and new target.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 4 2014-04-01 2014-04-01 false General principles; status of old target and new target. 1.338-1 Section 1.338-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Effects on Corporation § 1.338-1 General principles; status of old target and...

  12. Systems of Phraseological Machine Translation of Polythematic Texts from Russian into English and from English into Russian (RETRANS and ERTRANS Systems).

    ERIC Educational Resources Information Center

    Belonogov, G. G.; And Others

    1995-01-01

    Discusses the development of phraseological machine translation based on the theory that in natural languages, phraseological units cannot always be reduced to words. Describes the phraseological translation process of computer software and machine dictionary systems that translate Russian into English and English into Russian. (JMV)

  13. General principles for integrating geoheritage conservation in protected area management

    NASA Astrophysics Data System (ADS)

    Gordon, John E.; Crofts, Roger

    2015-04-01

    Development of more integrated approaches to the management of protected areas requires not only the protection of geosites, but also the effective application of geoconservation principles that apply more widely to the sustainable management of natural systems. Key guiding principles include: working with natural processes; managing natural systems and processes in a spatially integrated manner; accepting the inevitability of natural change; considering the responses of geomorphological processes to the effects of global climate change; recognising the sensitivity of natural systems and managing them within the limits of their capacity to absorb change; basing conservation management of active systems on a sound understanding of the underlying physical processes; making provision for managing visitors at sensitive sites; and acknowledging the interdependency of geodiversity and biodiversity management. As well as recognising the value of geoheritage in its own right, a more integrated approach to conservation across the full range of IUCN Protected Area Management Categories would benefit both biodiversity and geodiversity, through application of the concept of 'conserving nature's stage' and adopting an ecosystem approach.

  14. A generalized energy principle for a magnetorotational instability model

    NASA Astrophysics Data System (ADS)

    Tassi, Emanuele; Morrison, Phil; Tronko, Natalia

    2012-03-01

    We study the equilibria of the Magnetorotational Instability system by using the noncanonical Hamiltonian approach [1], since it provides variational principles for equilibria that can be used to assess stability. We show that a reduced system of equations derived in [2] is an infinite-dimensional noncanonical Hamiltonian system. The noncanonical Poisson bracket is identified and shown to obey the Jacobi identity, and families of Casimir invariants are obtained. Explicit sufficient conditions for the energy stability of two classes of equilibria are identified by means of the Energy-Casimir method. Comparison between the stability conditions obtained in the two cases indicates that the presence of an equilibirum magnetic field along the direction of the ignorable coordinate does not introduce destabilizing effects. An analogy is found and physically interpreted between terms of the MRI perturbation energy and terms appearing in the energy principle stability analysis of CRMHD for tokamaks [3].[4pt] [1] P. J. Morrison, Rev. Mod. Phys., 70, 467 (1998).[0pt] [2] K. Julien and E. Knobloch, Phil. Trans. Roy. Soc., 386A,1607 (2010).[0pt] [3] R.D. Hazeltine, et. al, Phys. Fluids 28, 2466 (1985).

  15. General principles regarding the use of adult stem cells.

    PubMed

    de Paula, I Carrasco

    2008-02-01

    With only a few, almost inevitable exceptions, biomedical research has developed within the last 50 years under the tutelage of ethical standards of notable precision. In the vast world of scientific investigation, few disciplines can boast of having realized documents of such ethical rigour, and respect for the integrity and intrinsic value of the human person has been one of the cardinal principles of the researcher. Research is intrinsic to the medical profession; the reward of research is knowledge and its techniques are ordered towards maintenance of human health. Since this end concerns human beings, it demands an extremely rigorous ethical approach. Ethical aspects are present from the first moments of the experimental project and occur on three levels: choice of the objectives, selection and use of the appropriate means for the study, and application of resultant new discoveries. Today, our moral attention cannot be reduced to a cost-benefit analysis. Biomedical sciences and medicine have overlapping areas of interest that can be sources of tension: the good of the subject versus scientific utility; profit versus complexity of research; liberty versus ethical and juridical bonds; the public versus the private; and the individual versus the community. Here, I attempt to formulate some essential principles that should guarantee humane measures for research on humans. PMID:18181949

  16. Physical anthropology: the search for general processes and principles.

    PubMed

    Lasker, G W

    1970-02-01

    Physical anthropology consists of two interdependent types of study: (1) the biological history of man and (2) general biological processes in man (such as mechanisms of evolution and growth). Popular interest may focus on the former, the fascinating story of the origin of man and of specific people, but the latter affords physical anthropology potential practical value in respect to medicine, dentistry, public health, and population policy. The study of general processes is the study of human beings in particular situations, not for what we can learn about these particular populations but for the sake of generalization about mankind anywhere in comparable situations. This is, of course, the purpose of experimental science in general, but in anthropology the method is usually comparative. Long ago the study of the growth of the two sexes and of children in different countries was started on a comparative basis as was the study of the so-called secular change in adult stature. By 1911 Franz Boas had compared the changes in stature and head form of children of several different immigrant groups in the United States. There have since been comparative studies of the amount and distribution of body fat (but not yet adequate comparative measurements of the relation of tissue components to diet and to diseases). Demographic patterns, inbreeding, outbreeding, and their effects are other general problems. The Human Adaptability Project of the International Biological Program promises studies of human response to heat, cold, altitude, and other conditions on a wide international basis. If supported, these could turn physical anthropology's search in a useful direction. The functional biology of people of even out-of-the-way communities will be compared with each other. These studies can yield general statements concerning human response to types of ecological situation including such sociocultural conditions as those of hunting-gathering tribes and urban slums. PMID:19681215

  17. [Guidelines: general principles and clinical application in nephrology].

    PubMed

    Feriozzi, S; Minutolo, R; Zoccali, C

    2014-01-01

    Clinical practice guidelines (GL) are multiplying and spreading throughout the scientific world. Nephrology is no exception and GL are more often recalled in the daily activity. Therefore, it can be useful to propose an excursus on the issue, to report the most important principles on the base of GL and moreover, to remember that GL are the synthesis between the scientific evidences published in literature and the critical analysis performed by an international committee of experts. Not all GL have the same clinical value. As a matter of fact, GL have a different strength of recommendation and grading according to the clinical evidences published. The number and methodological accuracy of the available studies on a specific subject are crucial to define the quality, the grading and the strength of GL. GL must also be shared with a wide number of specialists and other interested people such as patient organizations as well as health political institutions. Although the knowledge of GL is widespread, their practical use is still limited. The spreading of the knowledge regarding how GL are arranged, their appropriate reading about procedures and/or treatments to be done or not, it will convert GL into a reliable tool for daily clinical practice. Therefore it is not a confused and incomprehensible set of rules imposed by some scientific organizations. PMID:24777916

  18. Effect of the Generalized Uncertainty Principle on post-inflation preheating

    SciTech Connect

    Chemissany, Wissam; Das, Saurya; Ali, Ahmed Farag; Vagenas, Elias C. E-mail: saurya.das@uleth.ca E-mail: evagenas@academyofathens.gr

    2011-12-01

    We examine effects of the Generalized Uncertainty Principle, predicted by various theories of quantum gravity to replace the Heisenberg's uncertainty principle near the Planck scale, on post inflation preheating in cosmology, and show that it can predict either an increase or a decrease in parametric resonance and a corresponding change in particle production. Possible implications are considered.

  19. Students' Misunderstandings about the Energy Conservation Principle: A General View to Studies in Literature

    ERIC Educational Resources Information Center

    Tatar, Erdal; Oktay, Munir

    2007-01-01

    This paper serves to review previously reported studies on students' misunderstandings about the energy conservation principle (the first law of thermodynamics). Generally, studies in literature highlighted students' misunderstandings about the energy conservation principle stem from preliminaries about energy concept in daily life. Since prior…

  20. Laboratory Test Utilization Management: General Principles and Applications in Hematopathology.

    PubMed

    Reichard, Kaaren K; Wood, Adam J

    2016-03-01

    As the cost of health care continues to rise and reimbursement rates decrease, there is a growing demand and need to cut overall costs, enhance quality of services, and maintain as a top priority the needs and safety of the patient. In this article, we provide an introduction to test utilization and outline a general approach to creating an efficient, cost-effective test utilization strategy. We also present and discuss 2 test utilization algorithms that are evidence-based and may be of clinical utility as we move toward the future of doing the necessary tests at the right time. PMID:26940264

  1. A generalized Poisson solver for first-principles device simulations

    NASA Astrophysics Data System (ADS)

    Bani-Hashemian, Mohammad Hossein; Brück, Sascha; Luisier, Mathieu; VandeVondele, Joost

    2016-01-01

    Electronic structure calculations of atomistic systems based on density functional theory involve solving the Poisson equation. In this paper, we present a plane-wave based algorithm for solving the generalized Poisson equation subject to periodic or homogeneous Neumann conditions on the boundaries of the simulation cell and Dirichlet type conditions imposed at arbitrary subdomains. In this way, source, drain, and gate voltages can be imposed across atomistic models of electronic devices. Dirichlet conditions are enforced as constraints in a variational framework giving rise to a saddle point problem. The resulting system of equations is then solved using a stationary iterative method in which the generalized Poisson operator is preconditioned with the standard Laplace operator. The solver can make use of any sufficiently smooth function modelling the dielectric constant, including density dependent dielectric continuum models. For all the boundary conditions, consistent derivatives are available and molecular dynamics simulations can be performed. The convergence behaviour of the scheme is investigated and its capabilities are demonstrated.

  2. A generalized Poisson solver for first-principles device simulations.

    PubMed

    Bani-Hashemian, Mohammad Hossein; Brück, Sascha; Luisier, Mathieu; VandeVondele, Joost

    2016-01-28

    Electronic structure calculations of atomistic systems based on density functional theory involve solving the Poisson equation. In this paper, we present a plane-wave based algorithm for solving the generalized Poisson equation subject to periodic or homogeneous Neumann conditions on the boundaries of the simulation cell and Dirichlet type conditions imposed at arbitrary subdomains. In this way, source, drain, and gate voltages can be imposed across atomistic models of electronic devices. Dirichlet conditions are enforced as constraints in a variational framework giving rise to a saddle point problem. The resulting system of equations is then solved using a stationary iterative method in which the generalized Poisson operator is preconditioned with the standard Laplace operator. The solver can make use of any sufficiently smooth function modelling the dielectric constant, including density dependent dielectric continuum models. For all the boundary conditions, consistent derivatives are available and molecular dynamics simulations can be performed. The convergence behaviour of the scheme is investigated and its capabilities are demonstrated. PMID:26827208

  3. Earth Science Principles Pertinent to the General Education Programs in Junior High Schools

    ERIC Educational Resources Information Center

    Henson, Kenneth Tyrone

    1970-01-01

    Presents the procedures, and findings of a study designed to identify principles in astronomy, geology, meterology, oceanography and physical geography pertinent to general education programs in junior high schools. (LC)

  4. A generalized optimization principle for asymmetric branching in fluidic networks

    PubMed Central

    Stephenson, David

    2016-01-01

    When applied to a branching network, Murray’s law states that the optimal branching of vascular networks is achieved when the cube of the parent channel radius is equal to the sum of the cubes of the daughter channel radii. It is considered integral to understanding biological networks and for the biomimetic design of artificial fluidic systems. However, despite its ubiquity, we demonstrate that Murray’s law is only optimal (i.e. maximizes flow conductance per unit volume) for symmetric branching, where the local optimization of each individual channel corresponds to the global optimum of the network as a whole. In this paper, we present a generalized law that is valid for asymmetric branching, for any cross-sectional shape, and for a range of fluidic models. We verify our analytical solutions with the numerical optimization of a bifurcating fluidic network for the examples of laminar, turbulent and non-Newtonian fluid flows. PMID:27493583

  5. 25 CFR 42.1 - What general principles apply to this part?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What general principles apply to this part? 42.1 Section 42.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION STUDENT RIGHTS § 42.1 What general principles apply to this part? (a) This part applies to every Bureau-funded school. The regulations in this part govern student rights...

  6. 25 CFR 42.1 - What general principles apply to this part?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What general principles apply to this part? 42.1 Section 42.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION STUDENT RIGHTS § 42.1 What general principles apply to this part? (a) This part applies to every Bureau-funded school. The regulations in this part govern student rights...

  7. Entropy of the Randall-Sundrum brane world with the generalized uncertainty principle

    SciTech Connect

    Kim, Wontae; Park, Young-Jai; Kim, Yong-Wan

    2006-11-15

    By introducing the generalized uncertainty principle, we calculate the entropy of the bulk scalar field on the Randall-Sundrum brane background without any cutoff. We obtain the entropy of the massive scalar field proportional to the horizon area. Here, we observe that the mass contribution to the entropy exists in contrast to all previous results of the usual black hole cases with the generalized uncertainty principle.

  8. 25 CFR 42.1 - What general principles apply to this part?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What general principles apply to this part? 42.1 Section 42.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION STUDENT RIGHTS § 42.1 What general principles apply to this part? (a) This part applies to every Bureau-funded school. The regulations in this part govern student rights...

  9. 25 CFR 42.1 - What general principles apply to this part?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true What general principles apply to this part? 42.1 Section 42.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION STUDENT RIGHTS § 42.1 What general principles apply to this part? (a) This part applies to every Bureau-funded school. The regulations in this part govern student rights...

  10. 25 CFR 42.1 - What general principles apply to this part?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What general principles apply to this part? 42.1 Section 42.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION STUDENT RIGHTS § 42.1 What general principles apply to this part? (a) This part applies to every Bureau-funded school. The regulations in this part govern student rights...

  11. Generalized energy principle for flute perturbations in axisymmetric mirror machines

    SciTech Connect

    Lansky, I.M.; Ryutov, D.D.

    1993-01-20

    Axial symmetry is a very desirable property of the mirror devices both for fusion and neutron source applications. The main obstacle to be circumvented in the development of such systems, is the flute instability of axisymmetric mirrors. In recent years there appeared a number of proposals, devoted to the stabilization of the flute perturbations in the framework of axisymmetric magnetic configurations, which are based on the combining of the MHD unstable central cell with various types of end-cell stabilizers. In the present paper we concentrate ourselves just on this scheme, including long solenoid with a uniform field, conjugated with the end stabilizing anchor, intended to provide MHD stability of the system as a whole. The attractive feature of such a configuration is that it allows to exploit finite larmor radius (FLR) effects for the stabilization of the flute perturbations. As is well known, FLR effects, being strong, stabilize all flute modes, except the one with azimuthal number m = 1, corresponding to the ``rigid`` displacement of the plasma column (the ``global`` mode). Consequently, in the conditions when FLR effects dominate, the anchor has to stabilize the ``global` mode only. Bearing in mind a favorable influence of FLR effects we, however, don`t restrict our paper by discussion of only ``global`` mode stability and consider a general case of an arbitrary azimuthal mode.

  12. The dynamics of angular homeostasis: I. General principles.

    PubMed

    Murphy, E A; Berger, K R

    1987-02-01

    A general model is proposed casting aspects of ontogeny in quantitative terms amenable to genetic analysis. Its primordial construct is a chain of cells (termed a "pursuer") growing under the influence of a signal towards a fixed structure termed a "target." There is provision for graduated correction of the direction of growth of the pursuer. The determinants of scale include the size of the cells and the distance from the target. The minimum number of parameters is two: the initial angle of growth; and the force of the correction of errors of direction. Both are potentially of genetic interest. The impact of variation in these factors on the path of growth is studied. These findings are readily translated into biological terms, notably in congenital defects of the heart. Besides the primordial purposes, there are other objectives to the process. Some membranes require free edges, or large curvatures, or circular arrays. These secondary qualities require that the cells never reach the target. The target then becomes simply a construction point: that is, while remaining a center of attraction, it is no longer a true goal. If, because of undercorrection, the cell line misses the target at the first pass, it assumes a permanent orbit about it. The orbit rapidly comes to lie on a circle, with a radius independent of the initial angle of growth but related to the cell size and the restoration constant. From this property, several kinds of structures other than a simple bridge may result, especially when a series of lines of growth together form a tissue: a cusp, a free-floating membrane, or a circular membrane to fill a gap. PMID:3812596

  13. Concgramming: A Computer Driven Approach to Learning the Phraseology of English

    ERIC Educational Resources Information Center

    Greaves, Chris; Warren, Martin

    2007-01-01

    This study introduces a new computer-based methodology, "concgramming", that has as its primary aim the automatic identification of the phraseological profile and hence the "aboutness", of a text or corpus. It is argued that this methodology can be employed by language learners and teachers to raise awareness of the importance of the…

  14. Discovering the Hidden Treasure on the Internet: Using Google to Uncover the Veil of Phraseology

    ERIC Educational Resources Information Center

    Shei, Chi-Chiang

    2008-01-01

    Formulaic speech has been notoriously difficult to define and identify despite its crucial importance to native-like fluency and idiomaticity. In this article, I introduce a way of identifying phraseological units in a running text. I am interested in recurrent fragments like "charged with crimes against humanity" in texts which involve multiple…

  15. Investigating Academic Phraseology through Combinations of Very Frequent Words: A Methodological Exploration

    ERIC Educational Resources Information Center

    Vincent, Benet

    2013-01-01

    This study demonstrates an approach based on findings from phraseology which can be used to identify potentially useful phrases in a text by starting with continuous or discontinuous sequences of very frequent words. These combinations are then searched in a corpus of academic texts to find their common collocates and ascertain whether the…

  16. Collocational Processing in Light of the Phraseological Continuum Model: Does Semantic Transparency Matter?

    ERIC Educational Resources Information Center

    Gyllstad, Henrik; Wolter, Brent

    2016-01-01

    The present study investigates whether two types of word combinations (free combinations and collocations) differ in terms of processing by testing Howarth's Continuum Model based on word combination typologies from a phraseological tradition. A visual semantic judgment task was administered to advanced Swedish learners of English (n = 27) and…

  17. Adverbials of Result: Phraseology and Functions in the Problem-Solution Pattern

    ERIC Educational Resources Information Center

    Charles, Maggie

    2011-01-01

    This paper combines the use of corpus techniques with discourse analysis in order to investigate adverbials of result in the writing of advanced academic student writers. It focuses in detail on the phraseology and functions of "thus," "therefore," "then," "hence," "so" and "consequently." Two corpora of native-speaker theses are examined: 190,000…

  18. Uncovering the Extent of the Phraseological Tendency: Towards a Systematic Analysis of Concgrams

    ERIC Educational Resources Information Center

    Cheng, Winnie; Greaves, Chris; Sinclair, John McH.; Warren, Martin

    2009-01-01

    This paper offers an analytical procedure for identifying phraseological variation within "concgrams" (Cheng et al. 2006), which are sets of words that co-occur regardless of constituency variation (e.g. AB and A * B), positional variation (e.g. AB and BA), or both. It argues that examining concgrams takes us closer to more fully appreciating and…

  19. 76 FR 69333 - Derivatives Clearing Organization General Provisions and Core Principles

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ... 77576 (Dec. 13, 2010) (Core Principles A, H, N, and R (General Regulations)); and 75 FR 63113 (Oct. 14... in Sec. 1.3, which serves as the general definition section for all of the Commission's regulations... the CEA and Sec. 1.3(d) of the Commission's regulations. The Commission is adopting Sec. 39.1...

  20. Generalized Fermat's principle and action for light rays in a curved spacetime

    NASA Astrophysics Data System (ADS)

    Frolov, Valeri P.

    2013-09-01

    We start with formulation of the generalized Fermat’s principle for light propagation in a curved spacetime. We apply Pontryagin’s minimum principle of the optimal control theory and obtain an effective Hamiltonian for null geodesics in a curved spacetime. We explicitly demonstrate that dynamical equations for this Hamiltonian correctly reproduce null geodesic equations. Other forms of the action for light rays in a curved spacetime are also discussed.

  1. Communication: Maximum caliber is a general variational principle for nonequilibrium statistical mechanics.

    PubMed

    Hazoglou, Michael J; Walther, Valentin; Dixit, Purushottam D; Dill, Ken A

    2015-08-01

    There has been interest in finding a general variational principle for non-equilibrium statistical mechanics. We give evidence that Maximum Caliber (Max Cal) is such a principle. Max Cal, a variant of maximum entropy, predicts dynamical distribution functions by maximizing a path entropy subject to dynamical constraints, such as average fluxes. We first show that Max Cal leads to standard near-equilibrium results—including the Green-Kubo relations, Onsager's reciprocal relations of coupled flows, and Prigogine's principle of minimum entropy production—in a way that is particularly simple. We develop some generalizations of the Onsager and Prigogine results that apply arbitrarily far from equilibrium. Because Max Cal does not require any notion of "local equilibrium," or any notion of entropy dissipation, or temperature, or even any restriction to material physics, it is more general than many traditional approaches. It also applicable to flows and traffic on networks, for example. PMID:26254635

  2. Hierarchical maximum entropy principle for generalized superstatistical systems and Bose-Einstein condensation of light

    NASA Astrophysics Data System (ADS)

    Sob'yanin, Denis Nikolaevich

    2012-06-01

    A principle of hierarchical entropy maximization is proposed for generalized superstatistical systems, which are characterized by the existence of three levels of dynamics. If a generalized superstatistical system comprises a set of superstatistical subsystems, each made up of a set of cells, then the Boltzmann-Gibbs-Shannon entropy should be maximized first for each cell, second for each subsystem, and finally for the whole system. Hierarchical entropy maximization naturally reflects the sufficient time-scale separation between different dynamical levels and allows one to find the distribution of both the intensive parameter and the control parameter for the corresponding superstatistics. The hierarchical maximum entropy principle is applied to fluctuations of the photon Bose-Einstein condensate in a dye microcavity. This principle provides an alternative to the master equation approach recently applied to this problem. The possibility of constructing generalized superstatistics based on a statistics different from the Boltzmann-Gibbs statistics is pointed out.

  3. Communication: Maximum caliber is a general variational principle for nonequilibrium statistical mechanics

    NASA Astrophysics Data System (ADS)

    Hazoglou, Michael J.; Walther, Valentin; Dixit, Purushottam D.; Dill, Ken A.

    2015-08-01

    There has been interest in finding a general variational principle for non-equilibrium statistical mechanics. We give evidence that Maximum Caliber (Max Cal) is such a principle. Max Cal, a variant of maximum entropy, predicts dynamical distribution functions by maximizing a path entropy subject to dynamical constraints, such as average fluxes. We first show that Max Cal leads to standard near-equilibrium results—including the Green-Kubo relations, Onsager's reciprocal relations of coupled flows, and Prigogine's principle of minimum entropy production—in a way that is particularly simple. We develop some generalizations of the Onsager and Prigogine results that apply arbitrarily far from equilibrium. Because Max Cal does not require any notion of "local equilibrium," or any notion of entropy dissipation, or temperature, or even any restriction to material physics, it is more general than many traditional approaches. It also applicable to flows and traffic on networks, for example.

  4. The entropy of the noncommutative acoustic black hole based on generalized uncertainty principle

    NASA Astrophysics Data System (ADS)

    Anacleto, M. A.; Brito, F. A.; Passos, E.; Santos, W. P.

    2014-10-01

    In this paper we investigate statistical entropy of a 3-dimensional rotating acoustic black hole based on generalized uncertainty principle. In our results we obtain an area entropy and a correction term associated with the noncommutative acoustic black hole when λ introduced in the generalized uncertainty principle takes a specific value. However, in this method, it is not needed to introduce the ultraviolet cut-off and divergences are eliminated. Moreover, the small mass approximation is not necessary in the original brick-wall model.

  5. Generalization of Lieb's variational principle to Bogoliubov–Hartree–Fock theory

    SciTech Connect

    Bach, Volker Breteaux, Sébastien Menge, Edmund; Knörr, Hans Konrad

    2014-01-15

    In its original formulation, Lieb's variational principle holds for fermion systems with purely repulsive pair interactions. As a generalization we prove for both fermion and boson systems with semi-bounded Hamiltonian that the infimum of the energy over quasifree states coincides with the infimum over pure quasifree states. In particular, the Hamiltonian is not assumed to preserve the number of particles. To shed light on the relation between our result and the usual formulation of Lieb's variational principle in terms of one-particle density matrices, we also include a characterization of pure quasifree states by means of their generalized one-particle density matrices.

  6. [The General Principles of Suicide Prevention Policy from the perspective of clinical psychiatry].

    PubMed

    Cho, Yoshinori; Inagaki, Masatoshi

    2014-01-01

    In view of the fact that the suicide rate in Japan has remained high since 1998, the Basic Act on Suicide Prevention was implemented in 2006 with the objective of comprehensively promoting suicide prevention measures on a national scale. Based on this Basic Act, in 2007, the Japanese government formulated the General Principles of Suicide Prevention Policy as a guideline for recommended suicide prevention measures. These General Principles were revised in 2012 in accordance with the initial plan of holding a review after five years. The Basic Act places an emphasis on the various social factors that underlie suicides and takes the perspective that suicide prevention measures are also social measures. The slogan of the revised General Principles is "Toward Realization of a Society in which Nobody is Driven to Commit Suicide". The General Principles list various measures that are able to be used universally. These contents would be sufficient if the objective of the General Principles were "realization of a society that is easy to live in"; however, the absence of information on the effectiveness and order of priority for each measure may limit the specific effectiveness of the measures in relation to the actual prevention of suicide. In addition, considering that nearly 90% of suicide victims are in a state at the time of committing suicide in which a psychiatric disorder would be diagnosed, it would appear from a psychiatric standpoint that measures related to mental health, including expansion of psychiatric services, should be the top priority in suicide prevention measures. However, this is not the case in the General Principles, in either its original or revised form. Revisions to the General Principles related to clinical psychiatry provide more detailed descriptions of measures for individuals who unsuccessfully attempt suicide and identify newly targeted mental disorders other than depression; however, the overall proportion of contents relating to

  7. Generalized variational principle for the time-dependent Hartree-Fock equations for a Slater determinant

    PubMed

    Kull; Pfirsch

    2000-05-01

    The time-dependent Hartree-Fock equations are derived from a variational principle for the general N-body action of a Slater determinant of single-electron orbitals. The variational principle generalizes commonly used variational treatments based on reduced two-body actions. The self-consistent field equations are found to contain time-dependent corrections to the standard mean-field interactions. Their physical significance is discussed and a time-dependent phase shift to the Slater determinant is obtained that properly accounts for the total interaction energy in the mean-field approach. PMID:11031657

  8. Application of the generalized quasi-complementary energy principle to the fluid-solid coupling problem

    NASA Astrophysics Data System (ADS)

    Liang, Li-Fu; Liu, Zong-Min; Guo, Qing-Yong

    2009-03-01

    The fluid-solid coupling theory, an interdisciplinary science between hydrodynamics and solid mechanics, is an important tool for response analysis and direct design of structures in naval architecture and ocean engineering. By applying the corresponding relations between generalized forces and generalized displacements, convolutions were performed between the basic equations of elasto-dynamics in the primary space and corresponding virtual quantities. The results were integrated and then added algebraically. In light of the fact that body forces and surface forces are both follower forces, the generalized quasi-complementary energy principle with two kinds of variables for an initial value problem is established in non-conservative systems. Using the generalized quasi-complementary energy principle to deal with the fluid-solid coupling problem and to analyze the dynamic response of structures, a method for using two kinds of variables simultaneously for calculation of force and displacement was derived.

  9. 20 CFR 604.3 - Able and available requirement-general principles.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Able and available requirement-general principles. 604.3 Section 604.3 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR REGULATIONS FOR ELIGIBILITY FOR UNEMPLOYMENT COMPENSATION § 604.3 Able and available...

  10. 26 CFR 1.338-1 - General principles; status of old target and new target.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Effects on Corporation § 1.338-1 General principles; status... income tax purposes, referred to as the deemed asset sale and the income tax consequences thereof as the... Revenue Bulletin by the Internal Revenue Service. See § 601.601(d)(2)(ii) of this chapter. See,...

  11. 49 CFR Appendix E to Part 238 - General Principles of Reliability-Based Maintenance Programs

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false General Principles of Reliability-Based Maintenance Programs E Appendix E to Part 238 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PASSENGER EQUIPMENT SAFETY STANDARDS Pt. 238, App. E Appendix E to Part...

  12. The Basic Principles and Methods of the Music Curriculum for the General Education School.

    ERIC Educational Resources Information Center

    Kabalevskii, Dmitrii

    1988-01-01

    Delineates the foundations of Dmitri Kabalevskii's music curriculum for general education in the Soviet Union. Stresses teaching music as part of life itself. Bases teaching principles and methods on the song, dance, and march, termed "The Three Whales." Offers extensive lesson plans focusing on first grade music activities. (CH)

  13. Generalization of the diffusion equation by using the maximum entropy principle

    NASA Astrophysics Data System (ADS)

    Jumarie, Guy

    1985-06-01

    By using the so-called maximum entropy principle in information theory, one derives a generalization of the Fokker-Planck-Kolmogorov equation which applies when the n first transition moments of the process are proportional to Δt, while the other ones can be neglected.

  14. Using Domain-General Principles to Explain Children's Causal Reasoning Abilities

    ERIC Educational Resources Information Center

    McClelland, James L.; Thompson, Richard M.

    2007-01-01

    A connectionist model of causal attribution is presented, emphasizing the use of domain-general principles of processing and learning previously employed in models of semantic cognition. The model categorizes objects dependent upon their observed 'causal properties' and is capable of making several types of inferences that 4-year-old children have…

  15. 49 CFR Appendix E to Part 238 - General Principles of Reliability-Based Maintenance Programs

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Maintenance Programs E Appendix E to Part 238 Transportation Other Regulations Relating to Transportation... STANDARDS Pt. 238, App. E Appendix E to Part 238—General Principles of Reliability-Based Maintenance... reliability beyond the design reliability. (e) When a maintenance program is developed, it includes tasks...

  16. 21 CFR 570.20 - General principles for evaluating the safety of food additives.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 6 2013-04-01 2013-04-01 false General principles for evaluating the safety of food additives. 570.20 Section 570.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES Food...

  17. Victim Injury and Social Distance: A National Test of a General Principle of Conflict.

    PubMed

    Rennison, Callie Marie; Jacques, Scott; Allen, Andrea

    2016-01-01

    Our inquiry focuses on why some violent offenses but not others result in injury to the victim. Building on existing theory nested in the paradigm of pure sociology, we propose and test a general principle of conflict: Victim injury varies directly with social distance. This principle predicts that offenders are more likely to harm victims with whom they are less well acquainted and less similar culturally. We test three hypotheses derived from this principle with data from the National Crime Victimization Survey and find little support for the theory. Rather, findings suggest exactly the opposite of that predicted: As social distance between offender and victim increases, the odds of victim injury decreases. Recommendations of additional research are made. PMID:27302957

  18. Energy distribution of massless particles on black hole backgrounds with generalized uncertainty principle

    SciTech Connect

    Li Zhongheng

    2009-10-15

    We derive new formulas for the spectral energy density and total energy density of massless particles in a general spherically symmetric static metric from a generalized uncertainty principle. Compared with blackbody radiation, the spectral energy density is strongly damped at high frequencies. For large values of r, the spectral energy density diminishes when r grows, but at the event horizon, the spectral energy density vanishes and therefore thermodynamic quantities near a black hole, calculated via the generalized uncertainty principle, do not require any cutoff parameter. We find that the total energy density can be expressed in terms of Hurwitz zeta functions. It should be noted that at large r (low local temperature), the difference between the total energy density and the Stefan-Boltzmann law is too small to be observed. However, as r approaches an event horizon, the effect of the generalized uncertainty principle becomes more and more important, which may be observable. As examples, the spectral energy densities in the background metric of a Schwarzschild black hole and of a Schwarzschild black hole plus quintessence are discussed. It is interesting to note that the maximum of the distribution shifts to higher frequencies when the quintessence equation of state parameter w decreases.

  19. Maximum Principle for General Controlled Systems Driven by Fractional Brownian Motions

    SciTech Connect

    Han Yuecai; Hu Yaozhong; Song Jian

    2013-04-15

    We obtain a maximum principle for stochastic control problem of general controlled stochastic differential systems driven by fractional Brownian motions (of Hurst parameter H>1/2). This maximum principle specifies a system of equations that the optimal control must satisfy (necessary condition for the optimal control). This system of equations consists of a backward stochastic differential equation driven by both fractional Brownian motions and the corresponding underlying standard Brownian motions. In addition to this backward equation, the maximum principle also involves the Malliavin derivatives. Our approach is to use conditioning and Malliavin calculus. To arrive at our maximum principle we need to develop some new results of stochastic analysis of the controlled systems driven by fractional Brownian motions via fractional calculus. Our approach of conditioning and Malliavin calculus is also applied to classical system driven by standard Brownian motions while the controller has only partial information. As a straightforward consequence, the classical maximum principle is also deduced in this more natural and simpler way.

  20. Covariant energy–momentum and an uncertainty principle for general relativity

    SciTech Connect

    Cooperstock, F.I.; Dupre, M.J.

    2013-12-15

    We introduce a naturally-defined totally invariant spacetime energy expression for general relativity incorporating the contribution from gravity. The extension links seamlessly to the action integral for the gravitational field. The demand that the general expression for arbitrary systems reduces to the Tolman integral in the case of stationary bounded distributions, leads to the matter-localized Ricci integral for energy–momentum in support of the energy localization hypothesis. The role of the observer is addressed and as an extension of the special relativistic case, the field of observers comoving with the matter is seen to compute the intrinsic global energy of a system. The new localized energy supports the Bonnor claim that the Szekeres collapsing dust solutions are energy-conserving. It is suggested that in the extreme of strong gravity, the Heisenberg Uncertainty Principle be generalized in terms of spacetime energy–momentum. -- Highlights: •We present a totally invariant spacetime energy expression for general relativity incorporating the contribution from gravity. •Demand for the general expression to reduce to the Tolman integral for stationary systems supports the Ricci integral as energy–momentum. •Localized energy via the Ricci integral is consistent with the energy localization hypothesis. •New localized energy supports the Bonnor claim that the Szekeres collapsing dust solutions are energy-conserving. •Suggest the Heisenberg Uncertainty Principle be generalized in terms of spacetime energy–momentum in strong gravity extreme.

  1. General Principles of Radiation Protection in Fields of Diagnostic Medical Exposure

    PubMed Central

    2016-01-01

    After the rapid development of medical equipment including CT or PET-CT, radiation doses from medical exposure are now the largest source of man-made radiation exposure. General principles of radiation protection from the hazard of ionizing radiation are summarized as three key words; justification, optimization, and dose limit. Because medical exposure of radiation has unique considerations, diagnostic reference level is generally used as a reference value, instead of dose limits. In Korea, medical radiation exposure has increased rapidly. For medical radiation exposure control, Korea has two separate control systems. Regulation is essential to control medical radiation exposure. Physicians and radiologists must be aware of the radiation risks and benefits associated with medical exposure, and understand and implement the principles of radiation protection for patients. The education of the referring physicians and radiologists is also important. PMID:26908991

  2. On the reduction principle for differential equations with piecewise constant argument of generalized type

    NASA Astrophysics Data System (ADS)

    Akhmet, M. U.

    2007-12-01

    In this paper we introduce a new type of differential equations with piecewise constant argument (EPCAG), more general than EPCA [K.L. Cooke, J. Wiener, Retarded differential equations with piecewise constant delays, J. Math. Anal. Appl. 99 (1984) 265-297; J. Wiener, Generalized Solutions of Functional Differential Equations, World Scientific, Singapore, 1993]. The Reduction Principle [V.A. Pliss, The reduction principle in the theory of the stability of motion, Izv. Akad. Nauk SSSR Ser. Mat. 27 (1964) 1297-1324 (in Russian); V.A. Pliss, Integral Sets of Periodic Systems of Differential Equations, Nauka, Moskow, 1977 (in Russian)] is proved for EPCAG. The structure of the set of solutions is specified. We establish also the existence of global integral manifolds of quasilinear EPCAG in the so-called critical case and investigate the stability of the zero solution.

  3. A generalization of the Boltzmann superposition principle to polymer networks undergoing scission

    NASA Technical Reports Server (NTRS)

    Moacanin, J.; Landel, R. F.; Aklonis, J. J.

    1976-01-01

    Methods reported by Moacanin et al. (1975) and Moacanin and Aklonis (1971) are generalized with the objective to include strains (or stress) applied in an arbitrary manner to linearly viscoelastic materials. An imposition of changes in both the strain and the density of elastically effective chains in discrete increments is considered. In accordance with the Boltzmann superposition principle, each strain increment may be treated as a new independent experiment which adds linearly to the total response of the system.

  4. Effective geometries and generalized uncertainty principle corrections to the Bekenstein-Hawking entropy

    NASA Astrophysics Data System (ADS)

    Contreras, Ernesto; Villalba, Fabián D.; Bargueño, Pedro

    2016-06-01

    In this work we construct several black-hole metrics which are consistent with the generalized uncertainty principle logarithmic correction to the Bekenstein-Hawking entropy formula. After preserving the event horizon at the usual position, a singularity at the Planck scale is found. Finally, these geometries are shown to be realized by certain model of non-linear electrodynamics, which resembles previously studied regular black-hole solutions.

  5. 75 FR 10205 - Codex Alimentarius Commission: Meeting of the Codex Committee on General Principles

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-05

    ...The Office for Food Safety, U.S. Department of Agriculture (USDA), is sponsoring a public meeting on March 23, 2010. The objective of the public meeting is to provide information and receive public comments on agenda items and draft United States positions that will be discussed at the 26th session of the Codex Committee on General Principles (CCGP) of the Codex Alimentarius Commission......

  6. Variational principle of Bogoliubov and generalized mean fields in many-particle interacting systems

    NASA Astrophysics Data System (ADS)

    Kuzemsky, A. L.

    2015-07-01

    The approach to the theory of many-particle interacting systems from a unified standpoint, based on the variational principle for free energy is reviewed. A systematic discussion is given of the approximate free energies of complex statistical systems. The analysis is centered around the variational principle of Bogoliubov for free energy in the context of its applications to various problems of statistical mechanics. The review presents a terse discussion of selected works carried out over the past few decades on the theory of many-particle interacting systems in terms of the variational inequalities. It is the purpose of this paper to discuss some of the general principles which form the mathematical background to this approach and to establish a connection of the variational technique with other methods, such as the method of the mean (or self-consistent) field in the many-body problem. The method is illustrated by applying it to various systems of many-particle interacting systems, such as Ising, Heisenberg and Hubbard models, superconducting (SC) and superfluid systems, etc. This work proposes a new, general and pedagogical presentation, intended both for those who are interested in basic aspects and for those who are interested in concrete applications.

  7. Covariant energy-momentum and an uncertainty principle for general relativity

    NASA Astrophysics Data System (ADS)

    Cooperstock, F. I.; Dupre, M. J.

    2013-12-01

    We introduce a naturally-defined totally invariant spacetime energy expression for general relativity incorporating the contribution from gravity. The extension links seamlessly to the action integral for the gravitational field. The demand that the general expression for arbitrary systems reduces to the Tolman integral in the case of stationary bounded distributions, leads to the matter-localized Ricci integral for energy-momentum in support of the energy localization hypothesis. The role of the observer is addressed and as an extension of the special relativistic case, the field of observers comoving with the matter is seen to compute the intrinsic global energy of a system. The new localized energy supports the Bonnor claim that the Szekeres collapsing dust solutions are energy-conserving. It is suggested that in the extreme of strong gravity, the Heisenberg Uncertainty Principle be generalized in terms of spacetime energy-momentum.

  8. Community and job satisfactions: an argument for reciprocal influence based on the principle of stimulus generalization

    SciTech Connect

    Gavin, J.; Montgomery, J.C.

    1982-10-01

    The principle of stimulus generalization provided the underlying argument for a test of hypotheses regarding the association of community and job satisfactions and a critique of related theory and research. Two-stage least squares (2SLS) analysis made possible the examination of reciprocal causation, a notion inherent in the theoretical argument. Data were obtained from 276 employees of a Western U.S. coal mine as part of a work attitudes survey. The 2SLS analysis indicated a significant impact of community satisfaction on job satisfaction and an effect of borderline significance of job on community satisfaction. Theory-based correlational comparisons were made on groups of employees residing in four distinct communities, high and low tenure groups, males and females, and different levels in the mine's hierarchy. The pattern of correlations was generally consistent with predictions, but significance tests for differences yielded equivocal support. When considered in the context of previous studies, the data upheld a reciprocal causal model and the explanatory principle of stimulus generalization for understanding the relation of community and job satisfactions. Sample characteristics necessitate cautious interpretation and the model per se might best be viewed as a heuristic framework for more definitive research.

  9. First-principles generalized gradient approximation + U study of cubic CuAl2O4

    NASA Astrophysics Data System (ADS)

    Liu, Qi-Jun; Liu, Zheng-Tang

    2011-08-01

    We have investigated the electronic, magnetic, mechanical, and optical properties in cubic CuAl2O4 by a first-principles ultrasoft pseudopotential of the plane-wave within the density-functional theory (DFT) plus the generalized gradient approximation (GGA) + U (Hubbard parameter) formalism. We find the polarized hole dz2 character induced the dz2 magnetic orbital ordering and the p-d hybridization results in the covalent bonding between Cu and O. The origins of electrons transitions in dielectric function are consistent with electronic structure aroused by crystal-field and Janhn-Teller effect.

  10. Generalized uncertainty principle in f(R) gravity for a charged black hole

    SciTech Connect

    Said, Jackson Levi; Adami, Kristian Zarb

    2011-02-15

    Using f(R) gravity in the Palatini formularism, the metric for a charged spherically symmetric black hole is derived, taking the Ricci scalar curvature to be constant. The generalized uncertainty principle is then used to calculate the temperature of the resulting black hole; through this the entropy is found correcting the Bekenstein-Hawking entropy in this case. Using the entropy the tunneling probability and heat capacity are calculated up to the order of the Planck length, which produces an extra factor that becomes important as black holes become small, such as in the case of mini-black holes.

  11. Lifespan of rotating black hole in the frame of generalized uncertainty principle

    NASA Astrophysics Data System (ADS)

    He, Tangmei; Zhang, Jingyi; Yang, Jinbo; Tan, Hongwei

    2016-01-01

    In this paper, the lifespan under the generalized uncertainty principle (GUP) of rotating black hole is derived through the corrected radiation energy flux and the first law of the thermodynamics of black hole. The radiation energy flux indicates that there exist the highest temperature and the minimum mass both of which are relevant to the initial mass of the black hole in the final stage of the radiation. The lifespan of rotating black hole includes three terms: the dominant term is just the lifespan in the flat spacetime; the other two terms are individually induced by the rotation and the GUP.

  12. Impacts of generalized uncertainty principle on black hole thermodynamics and Salecker-Wigner inequalities

    SciTech Connect

    Tawfik, A.

    2013-07-01

    We investigate the impacts of Generalized Uncertainty Principle (GUP) proposed by some approaches to quantum gravity such as String Theory and Doubly Special Relativity on black hole thermodynamics and Salecker-Wigner inequalities. Utilizing Heisenberg uncertainty principle, the Hawking temperature, Bekenstein entropy, specific heat, emission rate and decay time are calculated. As the evaporation entirely eats up the black hole mass, the specific heat vanishes and the temperature approaches infinity with an infinite radiation rate. It is found that the GUP approach prevents the black hole from the entire evaporation. It implies the existence of remnants at which the specific heat vanishes. The same role is played by the Heisenberg uncertainty principle in constructing the hydrogen atom. We discuss how the linear GUP approach solves the entire-evaporation-problem. Furthermore, the black hole lifetime can be estimated using another approach; the Salecker-Wigner inequalities. Assuming that the quantum position uncertainty is limited to the minimum wavelength of measuring signal, Wigner second inequality can be obtained. If the spread of quantum clock is limited to some minimum value, then the modified black hole lifetime can be deduced. Based on linear GUP approach, the resulting lifetime difference depends on black hole relative mass and the difference between black hole mass with and without GUP is not negligible.

  13. General chemistry students' understanding of climate science principles relating to chemistry

    NASA Astrophysics Data System (ADS)

    Versprille, A. N.; Towns, M.; Mahaffy, P.; Martin, B.; McKenzie, L. C.; Kirchhoff, M.

    2012-12-01

    As part of the NSF funded Visualizing the Chemistry of Climate Science project, we are developing the chemistry of climate science inventory for use in general chemistry courses. The U.S. Climate Change Science Program (CCSP), which integrates federal research on climate and global change, has set out a climate literacy framework, Climate Literacy: the Essential Principles of Climate Science (US Climate Change Science Program, 2009). Developed by collaboration among NOAA, NASA, AAAS, and a distinguished group of scientists and educators, this Framework defines a set of essential principles and scientific thinking skills that a climate literate person should understand. We have based our interview protocol on misconceptions identified in the research literature and the essential principles of climate change outlined in the CCSP document that pertain to chemistry. We have interviewed 24 undergraduates to elicit their understanding of the Earth's energy system, global warming, climate change, greenhouse gases, climate, and weather. Our analysis and findings indicate that the fundamental science necessary to understand the Earth's energy system and climate change are not well understood by the undergraduates in this sample. Details of the interviews, analysis, and synthesis of findings will be shared.

  14. Ethical principles and the rationing of health care: a qualitative study in general practice

    PubMed Central

    Berney, Lee; Kelly, Moira; Doyal, Len; Feder, Gene; Griffiths, Chris; Jones, Ian Rees

    2005-01-01

    Background Researching sensitive topics, such as the rationing of treatments and denial of care, raises a number of ethical and methodological problems. Aim To describe the methods and findings from a number of focus group discussions that examined how GPs apply ethical principles when allocating scarce resources. Design of study A small-scale qualitative study involving purposive sampling, semi-structured interviews and focus groups. Setting Twenty-four GPs from two contrasting areas of London: one relatively affluent and one relatively deprived. Method Initial interviews asked GPs to identify key resource allocation issues. The interviews were transcribed and themes were identified. A number of case studies, each illustrative of an ethical issue related to rationing, were written up in the form of vignettes. In focus group discussions, GPs were given a number of these vignettes to debate. Results With respect to the ethical basis for decision making, the findings from this part of the study emphasised the role of social and psychological factors, the influence of the quality of the relationship between GPs and patients and confusion among GPs about their role in decision making. Conclusion The use of vignettes developed from prior interviews with GPs creates a non-threatening environment to discuss sensitive or controversial issues. The acceptance by GPs of general moral principles does not entail clarity of coherence of the application of these principles in practice. PMID:16105371

  15. Structural Evolutions of STOCK Markets Controlled by Generalized Entropy Principles of Complex Systems

    NASA Astrophysics Data System (ADS)

    Wang, Yi Jiao; Feng, Qing Yi; Chai, Li He

    As one of the most important financial markets and one of the main parts of economic system, the stock market has become the research focus in economics. The stock market is a typical complex open system far from equilibrium. Many available models that make huge contribution to researches on market are strong in describing the market however, ignoring strong nonlinear interactions among active agents and weak in reveal underlying dynamic mechanisms of structural evolutions of market. From econophysical perspectives, this paper analyzes the complex interactions among agents and defines the generalized entropy in stock markets. Nonlinear evolutionary dynamic equation for the stock markets is then derived from Maximum Generalized Entropy Principle. Simulations are accordingly conducted for a typical case with the given data, by which the structural evolution of the stock market system is demonstrated. Some discussions and implications are finally provided.

  16. Drugs Are Not Enough: Some Principles of Psychopharmacology for General Medical Practice

    PubMed Central

    Ross, W. Donald

    1963-01-01

    There is no necessary antagonism between the judicious use of drugs and a psychotherapeutic approach to patients in general medical practice. A table is presented with a simple pragmatic classification of types of drugs for altering emotional and mental states. Three general principles are given for the use of such drugs, illustrated by examples of the use and misuse of tranquillizers. Some differentiation is made between sedatives and tranquillizers and between different types of tranquillizers, particularly with reference to the need to consider depressive features in patients. Suggestions are made for the use of drugs for mild depressions and for depressions accompanying organic disease. One may have to take an “experimental” approach to new drugs to determine which to them are of value in relation to the particular emotional states of one's own patients. ImagesFig. 1 PMID:14060167

  17. Pearson's principle inspired generalized strategy for the fabrication of metal hydroxide and oxide nanocages.

    PubMed

    Nai, Jianwei; Tian, Yu; Guan, Xin; Guo, Lin

    2013-10-30

    Designing a general route for rational synthesis of a series or families of nanomaterials for emerging applications has become more and more fascinating and vital in the view of nanoscience and nanotechnology. Herein, we explore a general strategy for fabricating uniform nanocages of metal hydroxides (MHs) and metal oxides (MOs). A template-assisted route inspired by Pearson's hard and soft acid-base (HSAB) principle was employed for synthesizing MH nanocages via meticulous selection of the coordinating etchant as well as optimization of the reaction conditions. The concept of "coordinating etching" is successfully achieved in this work. This unique route shows potential in designing well-defined and high-quality MH nanocages with varying components, shell thicknesses, shapes, and sizes at room temperature. Consequently, porous MO nanocages can be obtained readily just through appropriate thermal treament of the respective MH nanocages. The overall strategy present in this work extends the application of the HSAB principle in nanoscience and offers a unqiue clue for rational fabrication of hollow (porous) and/or amorphous structures on the nanoscale, where these nanocages may present promising potential for various applications. PMID:23724779

  18. Capturing Phraseology in an Online Dictionary for Advanced Users of English as a Second Language: A Response to User Needs.

    ERIC Educational Resources Information Center

    McAlpine, Janice; Myles, Johanne

    2003-01-01

    Proposes a new type of English-as-a-Second-Language dictionary--in electronic form--that presents typical phraseology rather than words in isolation. Online, without the constraints of space and linear organization, the dictionary can treat the multiword lexical units and common collocational patterns that cohere around a node word and illustrate…

  19. Phraseological Patterns in Reporting Clauses Used in Citation: A Corpus-Based Study of Theses in Two Disciplines

    ERIC Educational Resources Information Center

    Charles, Maggie

    2006-01-01

    This study investigates the phraseological patterning that occurs in reporting clauses used to make references to others' research. It examines finite reporting clauses with "that"-clause complement and draws upon two corpora of theses written by native speakers in contrasting disciplines: approximately 190,000 words in politics/international…

  20. Using a problem-solving strategy to train students to apply general principles and to improve students' epistemology

    NASA Astrophysics Data System (ADS)

    McCoy, B.

    2011-12-01

    General studies science classes at many universities, such as physical science, Earth science, or astronomy, stress memorization and repetition of concepts. This approach leaves students with little appreciation for how science is used to explain phenomena from general principles. We present a novel instructional technique for an Earth science class in which the students are instructed in the use of a general problem solving strategy, adapted from a quantitative problem solving strategy developed by physics education research, in order to train the students in how to apply general principles. Using the Epistemological Beliefs Assessment for Physical Science, we have found that explicit training in problem solving significantly improves students' epistemology.

  1. General variational principle for spherically symmetric perturbations in diffeomorphism covariant theories

    SciTech Connect

    Seifert, Michael D.; Wald, Robert M.

    2007-04-15

    We present a general method for the analysis of the stability of static, spherically symmetric solutions to spherically symmetric perturbations in an arbitrary diffeomorphism covariant Lagrangian field theory. Our method involves fixing the gauge and solving the linearized gravitational field equations to eliminate the metric perturbation variables in terms of the matter variables. In a wide class of cases--which include f(R) gravity, the Einstein-aether theory of Jacobson and Mattingly, and Bekenstein's TeVeS theory--the remaining perturbation equations for the matter fields are second order in time. We show how the symplectic current arising from the original Lagrangian gives rise to a symmetric bilinear form on the variables of the reduced theory. If this bilinear form is positive definite, it provides an inner product that puts the equations of motion of the reduced theory into a self-adjoint form. A variational principle can then be written down immediately, from which stability can be tested readily. We illustrate our method in the case of Einstein's equation with perfect fluid matter, thereby rederiving, in a systematic manner, Chandrasekhar's variational principle for radial oscillations of spherically symmetric stars. In a subsequent paper, we will apply our analysis to f(R) gravity, the Einstein-aether theory, and Bekenstein's TeVeS theory.

  2. Robotic and mathematical modeling reveal general principles of appendage control and coordination in terrestrial locomotion

    NASA Astrophysics Data System (ADS)

    McInroe, Benjamin; Astley, Henry; Gong, Chaohui; Kawano, Sandy; Schiebel, Perrin; Choset, Howie; Goldman, Daniel I.

    The transition from aquatic to terrestrial life presented new challenges to early walkers, necessitating robust locomotion on complex, flowable substrates (e.g. sand, mud). Locomotion on such substrates is sensitive to limb morphology and kinematics. Although early walker morphologies are known, principles of appendage control remain elusive. To reveal limb control strategies that facilitated the invasion of land, we study both robotic and mathematical models. Robot experiments show that an active tail is critical for robust locomotion on granular media, enabling locomotion even with poor foot placement and limited ability to lift the body. Using a granular resistive force theory model, we construct connection vector fields that reveal how appendage coordination and terrain inclination impact locomotor performance. This model replicates experimental results, showing that moving limbs/tail in phase is most effective (suggesting a locomotor template). Varying limb trajectories and contacts, we find gaits for which tail use can be neutral or harmful, suggesting limb-tail coordination to be a nontrivial aspect of locomotion. Our findings show that robot experiments coupled with geometric mechanics provide a general framework to reveal principles of robust terrestrial locomotion. This work was supported by NSF PoLS.

  3. From general policy to legal rule: aspirations and limitations of the precautionary principle.

    PubMed Central

    Marchant, Gary E

    2003-01-01

    The rapid spread of the precautionary principle (PP) demonstrates the need to explicitly address the role of precaution in environmental decision making. Unfortunately, the PP in its current form is limited by the vagueness of, and variations in, the many formulations of the PP. This ambiguity in the meaning of the PP would not be so serious if the PP were limited to a general aspirational policy, but in every jurisdiction that has adopted the PP it has been transformed rapidly into a binding legal rule. As a legal rule, the ambiguity of the PP results in arbitrary application by regulatory agencies and reviewing courts and limits the capability of reviewing courts to perform their function in overseeing agency actions. To improve the explicit application of precaution, we must go beyond the current form of the PP and attempt to define the factors that weigh in favor of more or less precaution for specific risks. PMID:14594635

  4. Galilean and Lorentz Transformations in a Space with Generalized Uncertainty Principle

    NASA Astrophysics Data System (ADS)

    Tkachuk, V. M.

    2016-07-01

    We consider a space with Generalized Uncertainty Principle (GUP) which can be obtained in the frame of the deformed commutation relations. In the space with GUP we have found transformations relating coordinates and times of moving and rest frames of reference in the first order over the parameter of deformation. In the non-relativistic case we find the deformed Galilean transformation which is rotation in Euclidian space-time. This transformation is similar to the Lorentz one but written for Euclidean space-time where the speed of light is replaced by some velocity related to the parameter of deformation. We show that for relativistic particle in the space with GUP the coordinates of the rest and moving frames of reference satisfy the Lorentz transformation with some effective speed of light.

  5. Quantum corrections to the thermodynamics of Schwarzschild-Tangherlini black hole and the generalized uncertainty principle

    NASA Astrophysics Data System (ADS)

    Feng, Z. W.; Li, H. L.; Zu, X. T.; Yang, S. Z.

    2016-04-01

    We investigate the thermodynamics of Schwarzschild-Tangherlini black hole in the context of the generalized uncertainty principle (GUP). The corrections to the Hawking temperature, entropy and the heat capacity are obtained via the modified Hamilton-Jacobi equation. These modifications show that the GUP changes the evolution of the Schwarzschild-Tangherlini black hole. Specially, the GUP effect becomes susceptible when the radius or mass of the black hole approaches the order of Planck scale, it stops radiating and leads to a black hole remnant. Meanwhile, the Planck scale remnant can be confirmed through the analysis of the heat capacity. Those phenomena imply that the GUP may give a way to solve the information paradox. Besides, we also investigate the possibilities to observe the black hole at the Large Hadron Collider (LHC), and the results demonstrate that the black hole cannot be produced in the recent LHC.

  6. Generalizing Murray's law: An optimization principle for fluidic networks of arbitrary shape and scale

    NASA Astrophysics Data System (ADS)

    Stephenson, David; Patronis, Alexander; Holland, David M.; Lockerby, Duncan A.

    2015-11-01

    Murray's law states that the volumetric flow rate is proportional to the cube of the radius in a cylindrical channel optimized to require the minimum work to drive and maintain the fluid. However, application of this principle to the biomimetic design of micro/nano fabricated networks requires optimization of channels with arbitrary cross-sectional shape (not just circular) and smaller than is valid for Murray's original assumptions. We present a generalized law for symmetric branching that (a) is valid for any cross-sectional shape, providing that the shape is constant through the network; (b) is valid for slip flow and plug flow occurring at very small scales; and (c) is valid for networks with a constant depth, which is often a requirement for lab-on-a-chip fabrication procedures. By considering limits of the generalized law, we show that the optimum daughter-parent area ratio Γ, for symmetric branching into N daughter channels of any constant cross-sectional shape, is Γ=N-2 /3 for large-scale channels, and Γ=N-4 /5 for channels with a characteristic length scale much smaller than the slip length. Our analytical results are verified by comparison with a numerical optimization of a two-level network model based on flow rate data obtained from a variety of sources, including Navier-Stokes slip calculations, kinetic theory data, and stochastic particle simulations.

  7. Background, Principles, Implementation, and General Experiences of the North Karelia Project.

    PubMed

    Puska, Pekka; Vartiainen, Erkki; Nissinen, Aulikki; Laatikainen, Tiina; Jousilahti, Pekka

    2016-06-01

    The extremely high mortality of cardiovascular diseases in the 1960s in Finland, particularly in the Eastern Province of North Karelia and especially that of coronary heart disease in men, caused great concern among the local population. Action to reduce the problem was demanded in a petition signed in 1971 by the representatives of the population. In response, the North Karelia Project was launched in 1972 to carry out a comprehensive preventive project, first only in North Karelia as a national pilot (1972 to 1977), and thereafter continuing in North Karelia but at the same time transferring the experiences to a national level. The intervention was based on the at-that-time relatively new scientific information on the main causal risk factors. A comprehensive population-based intervention was carried out, aiming especially at the reduction of the high levels of serum cholesterol, blood pressure, and tobacco use, emphasizing general dietary changes and smoking reduction. A comprehensive monitoring and evaluation program was designed and implemented to learn from the experience in preparation for national and international use. Presented here are the background, principles, and general experiences of this project, which has made major contributions both to the contemporary public health work for the prevention and control of heart disease and noncommunicable diseases and for research in the area. PMID:27242083

  8. Over-constraint and a unified mobility method for general spatial mechanisms part 1: Essential principle

    NASA Astrophysics Data System (ADS)

    Zeng, Daxing; Lu, Wenjuan; Huang, Zhen

    2015-09-01

    Compared with the parallel mechanisms, the mobility analysis of the general multi-loop spatial mechanisms(GMSMs) is more difficult to obtain correct results. The reason is that its multi-loop is formed through several times of closings and there also exists motion coupling even strong coupling, where the over-constraints are concealed. However, the mobility analysis for this kind of mechanisms has been paid few attentions. A new systemic methodology for analyzing mobility is proposed for GMSMs also based on the screw theory. The key issue for mobility analysis is to recognize the over-constraint. Firstly, three theorems are given and point out: the reason and site of over-constraint occurrence, calculating the number of over-constraints by the screw theory, and how to analyze the over-constraints for a single-loop mechanism as well. Then, three closing forms for GMSMs are proposed including rigid closure, movable closure and dynamic closure, and for the three different forms the different analysis methods are also given. Especially, for the most difficult issue of GMSMs with the multi-loop closure in many times and the inevitable motion coupling, two important methods are proposed: "recognizing over-constraints by analyzing relative movement" and "recognizing over-constraints by virtual loop". The two methods are well used to solve the issue. Above-mentioned principles are not only systematic and effective but also unified. They provide a theoretical basis for the general multi-loop spatial mechanisms.

  9. Utilization of the seven principles for good practice in undergraduate education in general chemistry by community college instructors

    NASA Astrophysics Data System (ADS)

    Panther Bishoff, Jennifer

    In recent years, higher education has undergone many changes. The advent of assessment, accountability, and a newfound focus on teaching have required faculty to examine how they are teaching. Administrators and faculty are beginning to recognize that learning is not a "one size fits all" enterprise. To this end, Chickering and Gamson developed an inventory that examined faculty utilization of the Seven Principles of Good Practice in Undergraduate Education. The seven principles included by the authors included faculty-student interaction, cooperative learning, active learning, giving prompt feedback, emphasizing time on task, communicating high expectations, and respecting diverse talents and ways of learning. It was determined by Chickering and Gamson, as well as many other researchers, that these seven principles were hallmarks of successful undergraduate education. Community colleges are important institutions to study, as many students begin their higher education at two-year colleges. Most students are also required to take one or more science classes for their general education requirements; therefore, many students must take at least one general chemistry course. Both community colleges and chemistry are rarely studied in literature, which makes this study important. Community college general chemistry instructors were surveyed using an online version of Chickering and Gamson's Faculty Inventory for the Seven Principles of Good Practice in Undergraduate Education. Responses were analyzed, and it was discovered that not only did instructors utilize the principles to a different extent, but there were also differences between genders as well as between the specific actions related to each principle.

  10. [Multislice computerized tomography coronary angiography: general principles, technique and clinical applications].

    PubMed

    Karabulut, Nevzat

    2008-07-01

    Electrocardiogram-gated coronary multislice computerized tomography (CT) angiography is a rapidly improving technology allowing noninvasive imaging of coronary arteries. After the initial promising results obtained with four-section CT scanners, progressively higher temporal and spatial resolutions have been achieved by increasing gantry rotation speed and the number of detector rows and by reducing individual detector size. This review presents an overview of the general principles, technique and emerging applications and artifacts of coronary multislice CT angiography. The diagnostic performance of this new technology allows it to be used to evaluate the presence of coronary plaques and stenosis, coronary bypass graft patency, and the origin and course of congenital coronary anomalies. As it visualizes coronary artery wall in addition to lumen and provides volumetric data of heart and great vessels, it readily demonstrates plaque remodeling, ostial lesions and other cardiac and extracardiac abnormalities. The high negative predictive value of coronary CT angiography makes it a valuable tool in the evaluation of patients with low or intermediate pretest probability for coronary artery disease. However, improvements in spatial and temporal resolution are still needed in the imaging of small coronary stents, in the detection and characterization of noncalcified plaques, and to overcome image degradation by arrhythmias, higher heart rates, and calcium-related artifacts. PMID:18611837

  11. First-principles local density approximation + U and generalized gradient approximation + U study of plutonium oxides.

    PubMed

    Sun, Bo; Zhang, Ping; Zhao, Xian-Geng

    2008-02-28

    The electronic structure and properties of PuO2 and Pu2O3 have been studied from first principles by the all-electron projector-augmented-wave method. The local density approximation+U and the generalized gradient approximation+U formalisms have been used to account for the strong on-site Coulomb repulsion among the localized Pu 5f electrons. We discuss how the properties of PuO2 and Pu2O3 are affected by the choice of U as well as the choice of exchange-correlation potential. Also, oxidation reaction of Pu2O3, leading to formation of PuO2, and its dependence on U and exchange-correlation potential have been studied. Our results show that by choosing an appropriate U, it is promising to correctly and consistently describe structural, electronic, and thermodynamic properties of PuO2 and Pu2O3, which enable the modeling of redox process involving Pu-based materials possible. PMID:18315070

  12. General principles of irradiation therapy as applied to head and neck cancer.

    PubMed

    Harwood, A R; Keane, T J

    1982-04-01

    The general principles of irradiation therapy as applied to head and neck cancer are illustrated by discussion of typical radiation treatment planning for an early glottic carcinoma, carcinoma of the larynx with subglottic extension, a paranasal sinus carcinoma, and a localized tonsillar carcinoma. Each example shows how with modern techniques and careful planning radiation therapy can be directed homogeneously to any desired volume containing tumor but limiting the complications produced in the normal tissues. Homogeneous distribution of the dose of irradiation within the tumor is essential to avoid "cold" spots producing tumor recurrence and "hot" spots producing normal tissue complications. Improvements in technique of irradiation have halved the recurrence rate in T1 glottic cancer and reduced neck node recurrences in T1 supraglottic cancer from 19% to 3%. Techniques of implantation and the concept of therapeutic ratio are also discussed. The concepts of pre vs postoperative irradiation are discussed and the Toronto approach of delayed combined irradiation and surgery, which represents in our view the optimal combination of irradiation and surgery, is reviewed. PMID:7077732

  13. Multivariate statistical analysis and partitioning of sedimentary geochemical data sets: General principles and specific MATLAB scripts

    NASA Astrophysics Data System (ADS)

    Pisias, Nicklas G.; Murray, Richard W.; Scudder, Rachel P.

    2013-10-01

    Multivariate statistical treatments of large data sets in sedimentary geochemical and other fields are rapidly becoming more popular as analytical and computational capabilities expand. Because geochemical data sets present a unique set of conditions (e.g., the closed array), application of generic off-the-shelf applications is not straightforward and can yield misleading results. We present here annotated MATLAB scripts (and specific guidelines for their use) for Q-mode factor analysis, a constrained least squares multiple linear regression technique, and a total inversion protocol, that are based on the well-known approaches taken by Dymond (1981), Leinen and Pisias (1984), Kyte et al. (1993), and their predecessors. Although these techniques have been used by investigators for the past decades, their application has been neither consistent nor transparent, as their code has remained in-house or in formats not commonly used by many of today's researchers (e.g., FORTRAN). In addition to providing the annotated scripts and instructions for use, we discuss general principles to be considered when performing multivariate statistical treatments of large geochemical data sets, provide a brief contextual history of each approach, explain their similarities and differences, and include a sample data set for the user to test their own manipulation of the scripts.

  14. [Expectation for JSPN's contribution following revision of General Principles for Suicide Prevention Policy].

    PubMed

    Takeshima, Tadashi

    2014-01-01

    Japan's national suicide prevention efforts following the 1998 surge in the number of suicide deaths can be divided into three stages: the first stage administrated mainly by the health ministry (1998-2005), the second and transitional stage when it was upgraded to a full governmental issue (2005-2006), and the third and present stage following the promulgation of the Basic Act for Suicide Prevention in 2006. In June 2007, the General Principles for Suicide Prevention Policy (GPSP), a guideline on how the national government should act to promote suicide prevention, was announced, urging local governments to tackle the problem of suicide. The GPSP was set to be revised after around five years from its publication, and, thus, a revised GPSP was published in August of 2012. Based on the five years of challenges, the revised GPSP states that suicide prevention strategies should move on to more practical and community-oriented ones. The National Center of Neurology and Psychiatry (NCNP), through its Center for Suicide Prevention, played a coordinating role in putting forward a proposal for the revision, working with 29 academic societies including the Japanese Society of Psychiatry and Neurology (JSPN). In February 2013, by further developing the relationships with academic societies, etc., which were forged in the above-mentioned process, NCNP set up the Preparatory Committee for the Evidence-based Suicide Prevention Consortium in order to contribute to suicide prevention strategies from an academic perspective. Meanwhile, in the World Health Organization's 66th World Health Assembly held in May 2013, the Comprehensive Mental Health Action Plan 2013-2020 was approved. Its core principle is "no health without mental health", and it has the following four objectives: (1) to strengthen effective leadership and governance for mental health; (2) to provide comprehensive, integrated, and responsive mental health and social care services in community-based settings; (3) to

  15. Pleasure and pain: teaching neuroscientific principles of hedonism in a large general education undergraduate course.

    PubMed

    Bodnar, Richard J; Stellar, James R; Kraft, Tamar T; Loiacono, Ilyssa; Bajnath, Adesh; Rotella, Francis M; Barrientos, Alicia; Aghanori, Golshan; Olsson, Kerstin; Coke, Tricia; Huang, Donald; Luger, Zeke; Mousavi, Seyed Ali Reza; Dindyal, Trisha; Naqvi, Naveen; Kim, Jung-Yo

    2013-01-01

    In a large (250 registrants) general education lecture course, neuroscience principles were taught by two professors as co-instructors, starting with simple brain anatomy, chemistry, and function, proceeding to basic brain circuits of pleasure and pain, and progressing with fellow expert professors covering relevant philosophical, artistic, marketing, and anthropological issues. With this as a base, the course wove between fields of high relevance to psychology and neuroscience, such as food addiction and preferences, drug seeking and craving, analgesic pain-inhibitory systems activated by opiates and stress, neuroeconomics, unconscious decision-making, empathy, and modern neuroscientific techniques (functional magnetic resonance imaging and event-related potentials) presented by the co-instructors and other Psychology professors. With no formal assigned textbook, all lectures were PowerPoint-based, containing links to supplemental public-domain material. PowerPoints were available on Blackboard several days before the lecture. All lectures were also video-recorded and posted that evening. The course had a Facebook page for after-class conversation and one of the co-instructors communicated directly with students on Twitter in real time during lecture to provide momentary clarification and comment. In addition to graduate student Teaching Assistants (TAs), to allow for small group discussion, ten undergraduate students who performed well in a previous class were selected to serve as discussion leaders. The Discussion Leaders met four times at strategic points over the semester with groups of 20-25 current students, and received one credit of Independent Study, thus creating a course within a course. The course grade was based on weighted scores from two multiple-choice exams and a five-page writing assignment in which each student reviewed three unique, but brief original peer-review research articles (one page each) combined with expository writing on the first

  16. Pleasure and Pain: Teaching Neuroscientific Principles of Hedonism in a Large General Education Undergraduate Course

    PubMed Central

    Bodnar, Richard J.; Stellar, James R.; Kraft, Tamar T.; Loiacono, Ilyssa; Bajnath, Adesh; Rotella, Francis M.; Barrientos, Alicia; Aghanori, Golshan; Olsson, Kerstin; Coke, Tricia; Huang, Donald; Luger, Zeke; Mousavi, Seyed Ali Reza; Dindyal, Trisha; Naqvi, Naveen; Kim, Jung-Yo

    2013-01-01

    In a large (250 registrants) general education lecture course, neuroscience principles were taught by two professors as co-instructors, starting with simple brain anatomy, chemistry, and function, proceeding to basic brain circuits of pleasure and pain, and progressing with fellow expert professors covering relevant philosophical, artistic, marketing, and anthropological issues. With this as a base, the course wove between fields of high relevance to psychology and neuroscience, such as food addiction and preferences, drug seeking and craving, analgesic pain-inhibitory systems activated by opiates and stress, neuroeconomics, unconscious decision-making, empathy, and modern neuroscientific techniques (functional magnetic resonance imaging and event-related potentials) presented by the co-instructors and other Psychology professors. With no formal assigned textbook, all lectures were PowerPoint-based, containing links to supplemental public-domain material. PowerPoints were available on Blackboard several days before the lecture. All lectures were also video-recorded and posted that evening. The course had a Facebook page for after-class conversation and one of the co-instructors communicated directly with students on Twitter in real time during lecture to provide momentary clarification and comment. In addition to graduate student Teaching Assistants (TAs), to allow for small group discussion, ten undergraduate students who performed well in a previous class were selected to serve as discussion leaders. The Discussion Leaders met four times at strategic points over the semester with groups of 20–25 current students, and received one credit of Independent Study, thus creating a course within a course. The course grade was based on weighted scores from two multiple-choice exams and a five-page writing assignment in which each student reviewed three unique, but brief original peer-review research articles (one page each) combined with expository writing on the first

  17. 2 CFR Appendix A to Part 225 - General Principles for Determining Allowable Costs

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... appendix and other appendices to 2 CFR part 225 as “Federal awards”). The principles are for the purpose of... is outside the scope of 2 CFR part 225. 2. Policy guides. a. The application of these principles is... (including subawards) except those with (1) publicly-financed educational institutions subject to, 2 CFR...

  18. Precautionary Principles: General Definitions and Specific Applications to Genetically Modified Organisms

    ERIC Educational Resources Information Center

    Lofstedt, Ragnar E.; Fischhoff, Baruch; Fischhoff, Ilya R.

    2002-01-01

    Precautionary principles have been proposed as a fundamental element of sound risk management. Their advocates see them as guiding action in the face of uncertainty, encouraging the adoption of measures that reduce serious risks to health, safety, and the environment. Their opponents may reject the very idea of precautionary principles, find…

  19. Magnetic force microscopy: General principles and application to longitudinal recording media

    NASA Astrophysics Data System (ADS)

    Rugar, D.; Mamin, H. J.; Guethner, P.; Lambert, S. E.; Stern, J. E.; McFadyen, I.; Yogi, T.

    1990-08-01

    This paper discusses the principles of magnetic force microscopy (MFM) and its application to magnetic recording studies. We use the ac detection method which senses the force gradient acting on a small magnetic tip due to fields emanating from the domain structure in the sample. Tip fabrication procedures are described for two types of magnetic tips: etched tungsten wires with a sputter-deposited magnetic coating and etched nickel wires. The etched nickel wires are shown to have an apex radius on the order of 30 nm and a taper half-angle of approximately 3°. Lorentz-mode transmission electron microscopy of the nickel tips reveals that the final 20 μm is essentially single domain with magnetization approximately parallel with the tip axis. Images of written bit transitions are presented for several types of magnetic media, including CoPtCr, CoSm, and CoCr thin films, as well as γ-Fe2O3 particulate media. In general, the written magnetization patterns are seen with high contrast and with resolution better than 100 nm. A number of magnetic recording applications are discussed, including the investigation of overwrite behavior and the writing characteristics in CoSm media at high data density. Computer calculations were performed to simulate the MFM response to written magnetic transitions. By including the extended geometry of the tip, the nonparallel orientation of the cantilever, and the finite width of the magnetic transitions, good agreement with experiment was obtained. The model calculations correctly predict the experimentally observed change in image contrast that occurs as a function of tip orientation. Computer calculations showing the dependence of resolution on tip geometry are also presented.

  20. NSF Workshop Report: Discovering General Principles of Nervous System Organization by Comparing Brain Maps across Species

    PubMed Central

    Striedter, Georg F.; Belgard, T. Grant; Chen, Chun-Chun; Davis, Fred P.; Finlay, Barbara L.; Güntürkün, Onur; Hale, Melina E.; Harris, Julie A.; Hecht, Erin E.; Hof, Patrick R.; Hofmann, Hans A.; Holland, Linda Z.; Iwaniuk, Andrew N.; Jarvis, Erich D.; Karten, Harvey J.; Katz, Paul S.; Kristan, William B.; Macagno, Eduardo R.; Mitra, Partha P.; Moroz, Leonid L.; Preuss, Todd M.; Ragsdale, Clifton W.; Sherwood, Chet C.; Stevens, Charles F.; Stüttgen, Maik C.; Tsumoto, Tadaharu; Wilczynski, Walter

    2014-01-01

    Efforts to understand nervous system structure and function have received new impetus from the federal Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative. Comparative analyses can contribute to this effort by leading to the discovery of general principles of neural circuit design, information processing, and gene-structure-function relationships that are not apparent from studies on single species. We here propose to extend the comparative approach to nervous system ‘maps’ comprising molecular, anatomical, and physiological data. This research will identify which neural features are likely to generalize across species, and which are unlikely to be broadly conserved. It will also suggest causal relationships between genes, development, adult anatomy, physiology, and, ultimately, behavior. These causal hypotheses can then be tested experimentally. Finally, insights from comparative research can inspire and guide technological development. To promote this research agenda, we recommend that teams of investigators coalesce around specific research questions and select a set of ‘reference species’ to anchor their comparative analyses. These reference species should be chosen not just for practical advantages, but also with regard for their phylogenetic position, behavioral repertoire, well-annotated genome, or other strategic reasons. We envision that the nervous systems of these reference species will be mapped in more detail than those of other species. The collected data may range from the molecular to the behavioral, depending on the research question. To integrate across levels of analysis and across species, standards for data collection, annotation, archiving, and distribution must be developed and respected. To that end, it will help to form networks or consortia of researchers and centers for science, technology, and education that focus on organized data collection, distribution, and training. These activities could be

  1. Generalization of Abel's mechanical problem: The extended isochronicity condition and the superposition principle

    SciTech Connect

    Kinugawa, Tohru

    2014-02-15

    This paper presents a simple but nontrivial generalization of Abel's mechanical problem, based on the extended isochronicity condition and the superposition principle. There are two primary aims. The first one is to reveal the linear relation between the transit-time T and the travel-length X hidden behind the isochronicity problem that is usually discussed in terms of the nonlinear equation of motion (d{sup 2}X)/(dt{sup 2}) +(dU)/(dX) =0 with U(X) being an unknown potential. Second, the isochronicity condition is extended for the possible Abel-transform approach to designing the isochronous trajectories of charged particles in spectrometers and/or accelerators for time-resolving experiments. Our approach is based on the integral formula for the oscillatory motion by Landau and Lifshitz [Mechanics (Pergamon, Oxford, 1976), pp. 27–29]. The same formula is used to treat the non-periodic motion that is driven by U(X). Specifically, this unknown potential is determined by the (linear) Abel transform X(U) ∝ A[T(E)], where X(U) is the inverse function of U(X), A=(1/√(π))∫{sub 0}{sup E}dU/√(E−U) is the so-called Abel operator, and T(E) is the prescribed transit-time for a particle with energy E to spend in the region of interest. Based on this Abel-transform approach, we have introduced the extended isochronicity condition: typically, τ = T{sub A}(E) + T{sub N}(E) where τ is a constant period, T{sub A}(E) is the transit-time in the Abel type [A-type] region spanning X > 0 and T{sub N}(E) is that in the Non-Abel type [N-type] region covering X < 0. As for the A-type region in X > 0, the unknown inverse function X{sub A}(U) is determined from T{sub A}(E) via the Abel-transform relation X{sub A}(U) ∝ A[T{sub A}(E)]. In contrast, the N-type region in X < 0 does not ensure this linear relation: the region is covered with a predetermined potential U{sub N}(X) of some arbitrary choice, not necessarily obeying the Abel-transform relation. In discussing

  2. Generalization of Abel's mechanical problem: The extended isochronicity condition and the superposition principle

    NASA Astrophysics Data System (ADS)

    Kinugawa, Tohru

    2014-02-01

    This paper presents a simple but nontrivial generalization of Abel's mechanical problem, based on the extended isochronicity condition and the superposition principle. There are two primary aims. The first one is to reveal the linear relation between the transit-time T and the travel-length X hidden behind the isochronicity problem that is usually discussed in terms of the nonlinear equation of motion {d^2X}/{dt^2} + {dU}/{dX} = 0 with U(X) being an unknown potential. Second, the isochronicity condition is extended for the possible Abel-transform approach to designing the isochronous trajectories of charged particles in spectrometers and/or accelerators for time-resolving experiments. Our approach is based on the integral formula for the oscillatory motion by Landau and Lifshitz [Mechanics (Pergamon, Oxford, 1976), pp. 27-29]. The same formula is used to treat the non-periodic motion that is driven by U(X). Specifically, this unknown potential is determined by the (linear) Abel transform X(U) ∝ A[T(E)], where X(U) is the inverse function of U(X), A = (1/sqrt{π })int 0E {dU}/sqrt{E-U} is the so-called Abel operator, and T(E) is the prescribed transit-time for a particle with energy E to spend in the region of interest. Based on this Abel-transform approach, we have introduced the extended isochronicity condition: typically, τ = TA(E) + TN(E) where τ is a constant period, TA(E) is the transit-time in the Abel type [A-type] region spanning X > 0 and TN(E) is that in the Non-Abel type [N-type] region covering X < 0. As for the A-type region in X > 0, the unknown inverse function XA(U) is determined from TA(E) via the Abel-transform relation XA(U) ∝ A[TA(E)]. In contrast, the N-type region in X < 0 does not ensure this linear relation: the region is covered with a predetermined potential UN(X) of some arbitrary choice, not necessarily obeying the Abel-transform relation. In discussing the isochronicity problem, there has been no attempt of N-type regions that are

  3. A Dark Energy Model with Generalized Uncertainty Principle in the Emergent, Intermediate and Logamediate Scenarios of the Universe

    NASA Astrophysics Data System (ADS)

    Ghosh, Rahul; Chattopadhyay, Surajit; Debnath, Ujjal

    2012-02-01

    This work is motivated by the work of Kim et al. (Mod. Phys. Lett. A 23:3049, 2008), which considered the equation of state parameter for the new agegraphic dark energy based on generalized uncertainty principle coexisting with dark matter without interaction. In this work, we have considered the same dark energy interacting with dark matter in emergent, intermediate and logamediate scenarios of the universe. Also, we have investigated the statefinder, kerk and lerk parameters in all three scenarios under this interaction. The energy density and pressure for the new agegraphic dark energy based on generalized uncertainty principle have been calculated and their behaviors have been investigated. The evolution of the equation of state parameter has been analyzed in the interacting and non-interacting situations in all the three scenarios. The graphical analysis shows that the dark energy behaves like quintessence era for logamediate expansion and phantom era for emergent and intermediate expansions of the universe.

  4. Quantum statistical entropy and minimal length of 5D Ricci-flat black string with generalized uncertainty principle

    SciTech Connect

    Liu Molin; Gui Yuanxing; Liu Hongya

    2008-12-15

    In this paper, we study the quantum statistical entropy in a 5D Ricci-flat black string solution, which contains a 4D Schwarzschild-de Sitter black hole on the brane, by using the improved thin-layer method with the generalized uncertainty principle. The entropy is the linear sum of the areas of the event horizon and the cosmological horizon without any cutoff and any constraint on the bulk's configuration rather than the usual uncertainty principle. The system's density of state and free energy are convergent in the neighborhood of horizon. The small-mass approximation is determined by the asymptotic behavior of metric function near horizons. Meanwhile, we obtain the minimal length of the position {delta}x, which is restrained by the surface gravities and the thickness of layer near horizons.

  5. [Basic trends in general human pathology and principles of its teaching in higher medical education].

    PubMed

    Khitrov, N K; Sarkisov, D S; Romadanova, N B

    1994-01-01

    The paper considers the current trends in the development of biological and medical sciences: their subject, tasks, methods, and place of General Human Pathology among other subjects, its value for the clinical discipline. It defines and analyzes the most topical and disputable directions of General Human Pathology, primarily including those which form the bases for the pathology theory. Arguments are advanced for the necessity of introducing the subject General Pathology of Man into the curriculum of higher medical educational establishments at various faculties. Consideration is given to the specific features of this subject teaching at the faculty training researchers and research pedagogical personnel, at the Pharmaceutical and Higher Nurse Training Faculties of the I. M. Sechenov Moscow Medical Academy. A proposal is given to consider and to discuss the most important problems of General Pathology and its teaching, which are listed in the paper. PMID:7524869

  6. Ethics in medical research: General principles with special reference to psychiatry research

    PubMed Central

    Avasthi, Ajit; Ghosh, Abhishek; Sarkar, Sidharth; Grover, Sandeep

    2013-01-01

    Ethics is an understanding of the nature of conflicts arising from moral imperatives and how best we may deal with them. Ethics in medical research deals with the conflicts of interest across various levels. Guidelines have been proposed for standardized ethical practice throughout the globe. The four fundamental principles of ethics which are being underscored are autonomy, non-maleficence, beneficence, and justice. Some special ethical issues have particular relevance to psychiatric research arising primarily from the specific vulnerabilities of those with mental illness and the risks posed by some research methodologies. Accordingly, sensitivity is required in the design of psychiatric research. It is suggested that though the value of published guidelines and the help that may be available from research ethics committees is quite great, the primary responsibility for maintaining high standards of practice in research rests with research workers themselves. PMID:23440168

  7. Water, Resilience and the Law: From General Concepts and Governance Design Principles to Actionable Mechanisms

    NASA Astrophysics Data System (ADS)

    Hill Clarvis, M.; Allan, A.; Hannah, D. M.

    2013-12-01

    Climate change has significant ramifications for water law and governance, yet, there is strong evidence that legal regulations have often failed to protect environments or promote sustainable development. Scholars have increasingly suggested that the preservation and restoration paradigms of legislation and regulation are no longer adequate for climate change related challenges in complex and cross-scale social-ecological systems. This is namely due to past assumptions of stationarity, uniformitarianism and the perception of ecosystem change as predictable and reversible. This paper reviews the literature on law and resilience and then presents and discusses a set of practical examples of legal mechanisms from the water resources management sector, identified according to a set of guiding principles from the literature on adaptive capacity, adaptive governance as well as adaptive and integrated water resources management. It then assesses the aptness of these different measures according to scientific evidence of increased uncertainty and changing ecological baselines. A review of the best practice examples demonstrates that there are a number of best practice examples attempting to integrate adaptive elements of flexibility, iterativity, connectivity and subsidiarity into a variety of legislative mechanisms, suggesting that there is not as significant a tension between resilience and the law as many scholars have suggested. However, while many of the mechanisms may indeed be suitable for addressing challenges relating to current levels of change and uncertainty, analysis across a broader range of uncertainty highlights challenges relating to more irreversible changes associated with greater levels of warming. Furthermore the paper identifies a set of pre-requisites that are fundamental to the successful implementation of such mechanisms, namely monitoring and data sharing, financial and technical capacity, particularly in nations that are most at risk with the

  8. Generalization of the Brodsky-Lepage-Mackenzie optimization within the {β }-expansion and the principle of maximal conformality

    NASA Astrophysics Data System (ADS)

    Kataev, A. L.; Mikhailov, S. V.

    2015-01-01

    We discuss generalizations of the Brodsky-Lepage-Mackenzie optimization procedure for renormalization group invariant quantities. In this respect, we discuss in detail the features and construction of the {β } -expansion presentation instead of the standard perturbative series with regard to the Adler D function and Bjorken polarized sum rules obtained in the order of O (αs4) . Based on the {β } expansion, we analyze different schemes of optimization, including the corrected principle of maximal conformality, numerically illustrating their results. We suggest our scheme for the series optimization and apply it to both the above quantities.

  9. General proof of the entropy principle for self-gravitating fluid in static spacetimes

    NASA Astrophysics Data System (ADS)

    Fang, Xiongjun; Gao, Sijie

    2014-08-01

    We show that for any perfect fluid in a static spacetime, if the Einstein constraint equation is satisfied and the temperature of the fluid obeys Tolman's law, then the other components of Einstein's equation are implied by the assumption that the total entropy of the fluid achieves an extremum for fixed total particle number and for all variations of metric with certain boundary conditions. Conversely, one can show that the extrema of the total entropy of the fluid are implied by Einstein's equation. Compared to previous works on this issue, we do not require spherical symmetry for the spacetime. Our results suggest a general and solid connection between thermodynamics and general relativity.

  10. 21 CFR 312.22 - General principles of the IND submission.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... likelihood that the investigations will yield data capable of meeting statutory standards for marketing... manufacturer's IND or marketing application should follow the same general format, but ordinarily may, if authorized by the manufacturer, refer to the manufacturer's IND or marketing application in providing...

  11. Extending the generality of leaf economic design principles in the cycads, an ancient lineage.

    PubMed

    Zhang, Yong-Jiang; Cao, Kun-Fang; Sack, Lawren; Li, Nan; Wei, Xue-Mei; Goldstein, Guillermo

    2015-04-01

    Cycads are the most ancient lineage of living seed plants, but the design of their leaves has received little study. We tested whether cycad leaves are governed by the same fundamental design principles previously established for ferns, conifers and angiosperms, and characterized the uniqueness of this relict lineage in foliar trait relationships. Leaf structure, photosynthesis, hydraulics and nutrient composition were studied in 33 cycad species from nine genera and three families growing in two botanical gardens. Cycads varied greatly in leaf structure and physiology. Similarly to other lineages, light-saturated photosynthetic rate per mass (Am ) was related negatively to leaf mass per area and positively to foliar concentrations of chlorophyll, nitrogen (N), phosphorus and iron, but unlike angiosperms, leaf photosynthetic rate was not associated with leaf hydraulic conductance. Cycads had lower photosynthetic N use efficiency and higher photosynthetic performance relative to hydraulic capacity compared with other lineages. These findings extend the relationships shown for foliar traits in angiosperms to the cycads. This functional convergence supports the modern synthetic understanding of leaf design, with common constraints operating across lineages, even as they highlight exceptional aspects of the biology of this key relict lineage. PMID:25622799

  12. The effect of generalized uncertainty principle on square well, a case study

    SciTech Connect

    Ma, Meng-Sen; Zhao, Ren

    2014-08-15

    According to a special case (β = 0) of the generalized uncertainty relation we derive the energy eigenvalues of the infinite potential well. It is shown that the obtained energy levels are different from the usual result with some correction terms. And the correction terms of the energy eigenvalues are independent of other parameters except α. But the eigenstates will depend on another two parameters besides α.

  13. A Z{sub 3} generalization of Pauli's principle, quark algebra and the Lorentz invariance

    SciTech Connect

    Kerner, Richard

    2012-09-24

    The fundamental difference between bosons and fermions is that they obey two alternative representations of the Z{sub 2} group, resulting in symmetric or anti-symmetric binary commutation relations. Our aim is to explore possibilities offered by ternary Z{sub 3} generalization commutation relations. This leads to cubic and ternary algebras which are a direct generalization of usual commutation relations, with Z{sub 3}-grading replacing the usual Z{sub 2}-grading. Properties and structure of such algebras are discussed, with special interest in a low-dimensional one, with two generators. Invariant cubic forms on such algebras are introduced, and it is shown how the SL(2,C) group arises naturally as the symmetry group preserving these forms. In the case of lowest dimension, with only two generators, it is shown how the cubic combinations of elements of the same Z{sub 3} grade behave like Lorentz spinors, while binary products of elements of this algebra with an element of the conjugate algebra behave like Lorentz vectors. The wave equation generalizing the Dirac operator to the Z{sub 3}-graded case is introduced, whose diagonalization leads to a third-order equation. The solutions of this equation cannot propagate because their exponents always contain non-oscillating real damping factor. We show how certain cubic products can propagate nevertheless. The model suggests the origin of the color SU(3) symmetry obeyed by quark states.

  14. On extracting design principles from biology: I. Method-General answers to high-level design questions for bioinspired robots.

    PubMed

    Haberland, M; Kim, S

    2015-01-01

    When millions of years of evolution suggest a particular design solution, we may be tempted to abandon traditional design methods and copy the biological example. However, biological solutions do not often translate directly into the engineering domain, and even when they do, copying eliminates the opportunity to improve. A better approach is to extract design principles relevant to the task of interest, incorporate them in engineering designs, and vet these candidates against others. This paper presents the first general framework for determining whether biologically inspired relationships between design input variables and output objectives and constraints are applicable to a variety of engineering systems. Using optimization and statistics to generalize the results beyond a particular system, the framework overcomes shortcomings observed of ad hoc methods, particularly those used in the challenging study of legged locomotion. The utility of the framework is demonstrated in a case study of the relative running efficiency of rotary-kneed and telescoping-legged robots. PMID:25643176

  15. Major Upgrade of the Reactor Dosimetry Interpretation Methodology Used at the CEA General Principle

    NASA Astrophysics Data System (ADS)

    Destouches, C.; Gregoire, G.; Beretz, D.; Bourganel, S.; Chiron, M.

    2009-08-01

    , this paper lists the main improvements of the neutron calculation codes and of the international nuclear data libraries. The principle of the new interpretation process is then detailed and a derivation process for the associated uncertainties is exposed. The paper finally analyzes the improvements expected from the refined process.

  16. Management of animal health emergencies: general principles and legal and international obligations.

    PubMed

    Marabelli, R; Ferri, G; Bellini, S

    1999-04-01

    The Eighth Round of the General Agreement on Tariffs and Trade led to the creation of the World Trade Organization and to the adoption of the Sanitary and Phytosanitary (SPS) Agreement, thus considerably changing the rules of international trade in animals and animal products. Animal health measures may result in trade restrictions, but governments accept that these restrictions may sometimes be necessary and appropriate to ensure food safety and animal health protection. The SPS Agreement acknowledges the rights of governments to adopt measure to protect human, animal and plant health. To ensure effective animal health protection, without unjustifiable discrimination, the operational procedures of Veterinary Services must be standardised, especially those concerning disease notification, epidemiological information, certification for international trade and management of animal health emergencies. Veterinary Services must be further supported by a proper legislative framework and adequate financial resources. PMID:10190200

  17. Management of menorrhagia in women with inherited bleeding disorders: general principles and use of desmopressin.

    PubMed

    Rodeghiero, F

    2008-01-01

    The haemostatic system has a central role in controlling the amount and the duration of menstrual bleeding, thus abnormally prolonged or profuse bleeding does occur in most women affected by inherited bleeding disorders. Whereas irregular, premenarchal or postmenopausal uterine bleeding is unusual in inherited or acquired heamorrhagic disorders, severe acute bleeding and menorrhagia at menarche and chronic menorrhagia during the entire reproductive life are common manifestations. Prevalence and morbidity of menorrhagia in inherited bleeding disorders have been poorly investigated. It can be estimated that 40% to 60% of currently menstruating women with type 1 or 2 and more than 60% of women with type 3 VWD complain of menorrhagia with a significant impact on their quality of life. Menorrhagia may be particularly distressing in adolescents because of their delicate emotional equilibrium. Similar epidermiology has been described in other inherited disorders like factor XI deficiency, platelet functional defects and in carriers of haemophilia A and B. Women presenting with ''isolated'' menorrhagia, that is without significant additional bleeding symptoms, a situation reported by up to 15% of healthy women, do not demand investigation to exclude an occult bleeding disorder. A multidisciplinary approach is required for diagnosis and treatment. Gynaecological supervision is always required to exclude organic causes unmasked by the bleeding disorder. Treatment options are similar to those for menorrhagia in general with the addition of desmopressin and replacement therapy and the exclusion of non-steroidal anti-inflammatory drugs. The therapeutic plan should take into consideration the patient's preferences, age and severity of bleeding. Iron supplementation is of paramount importance. Remedies used in clinical practice for menorrhagia in general (tranexamic acid, combined oral contraceptives [COC], levonorgestrel intrauterine system [LNG-IUS]) are first tried. In case of

  18. Receptor-mediated tumor targeting with radiopeptides. Part 1. General principles and methods.

    PubMed

    Eberle, Alex N; Mild, Gabriele

    2009-01-01

    Radiolabeled peptides have become important tools for preclinical cancer research, and in nuclear oncology they serve as diagnostic and more recently also as therapeutic agents. In the latter application, radiolabeled peptides represent a distinct sector of the molecular targeting approach, which in many areas of therapy implements the old "magic bullet" concept by specifically directing the therapeutic agent to the site of action. Although in the past few years the development of receptor-mediated targeting for therapy has been confined to some radiolabeled antibodies and to somatostatin/SRIF, research into an increasing number of radiolabeled peptides and their receptors expressed by different tumors will soon lead to a wider use of peptide radiopharmaceuticals. In a consecutive series of six reviews we present a comprehensive overview of the literature on receptor-mediated tumor targeting with the different radiopeptides currently studied. Part 1 summarizes the concepts and methods of radiopeptide targeting, the selection of radioisotopes, chelators, the criteria of peptide ligand development and some general aspects of diagnostic and therapeutic application of peptide radiopharmaceuticals. PMID:19519167

  19. Queensland general practitioners' applications of the "mature minor" principle: the role of patient age and gender.

    PubMed

    Teoludzka, Anna; Bartholomew, Terence P

    2010-12-01

    Most Australian jurisdictions do not have legislation that stipulates an age by which a minor can make their own medical treatment decisions. Instead, they rely on Gillick v West Norfolk and Wisbech Area Health Authority [1986] AC 112, an English common law decision that recommends individual assessments of "maturity". This study explores how medical practitioners in the State of Queensland understand and apply this legal authority when faced with a young person wishing to make a contentious medical treatment decision. Almost 200 doctors made decisions about a hypothetical patient's competence and confidentiality, and detailed their reasoning in an open-ended format. The data indicate that the vagaries of existing legal criteria allow for a range of philosophical perspectives and idiosyncratic heuristics to play a role in assessment practices, and that particular combinations of patient age and gender made these cognitive shortcuts more likely to occur. A notable proportion of such processes are not consistent with legal guidelines, and this has implications for general practitioners' vulnerability to litigation as well as young patients' treatment trajectories. PMID:21355438

  20. River and Wetland Food Webs in Australia's Wet-Dry Tropics: General Principles and Implications for Management.

    NASA Astrophysics Data System (ADS)

    Douglas, M. M.; Bunn, S. E.; Davies, P. M.

    2005-05-01

    The tropical rivers of northern Australia are internationally recognised for their high ecological and cultural values. They have largely unmodified flow regimes and are comparatively free of the impacts associated with intensive land use. However, there is growing demand for agricultural development and existing pressures, such as weeds and feral animals, threaten their ecological integrity. Using the international literature to provide a conceptual framework and drawing on limited published and unpublished data on rivers in northern Australia, we have derived five general principles about food webs and related ecosystem processes that both characterise tropical rivers of northern Australia and have important implications for their management. These are: (1) Seasonal hydrology is a strong driver of ecosystem processes and food web structure; (2) Hydrological connectivity is largely intact and underpins important terrestrial-aquatic food web subsidies; (3) River and wetland food webs are strongly dependent on algal production; (4) A few common macroconsumers species have a strong influence on benthic food webs; (5) Omnivory is widespread and food chains are short. These principles have implications for the management and protection of tropical rivers and wetlands of northern Australia and provide a framework for the formation of testable hypotheses in future research programs.

  1. Viewing brain processes as Critical State Transitions across levels of organization: Neural events in Cognition and Consciousness, and general principles.

    PubMed

    Werner, Gerhard

    2009-04-01

    In this theoretical and speculative essay, I propose that insights into certain aspects of neural system functions can be gained from viewing brain function in terms of the branch of Statistical Mechanics currently referred to as "Modern Critical Theory" [Stanley, H.E., 1987. Introduction to Phase Transitions and Critical Phenomena. Oxford University Press; Marro, J., Dickman, R., 1999. Nonequilibrium Phase Transitions in Lattice Models. Cambridge University Press, Cambridge, UK]. The application of this framework is here explored in two stages: in the first place, its principles are applied to state transitions in global brain dynamics, with benchmarks of Cognitive Neuroscience providing the relevant empirical reference points. The second stage generalizes to suggest in more detail how the same principles could also apply to the relation between other levels of the structural-functional hierarchy of the nervous system and between neural assemblies. In this view, state transitions resulting from the processing at one level are the input to the next, in the image of a 'bucket brigade', with the content of each bucket being passed on along the chain, after having undergone a state transition. The unique features of a process of this kind will be discussed and illustrated. PMID:19124060

  2. General hypothesis for nanowire synthesis. I. Extended principles and evidential (experimental and theoretical) demonstration

    NASA Astrophysics Data System (ADS)

    Noor Mohammad, S.

    2011-09-01

    Nanowires, nanotubes, and nanodots (quantum dots) are nanomaterials (NMTs). While nanodots are miniaturized nanowires, nanotubes are hollow nanowires. A universal model for basic science of the synthesis and characteristics of NMTs must be established. To achieve this goal, a general hypothesis has been presented. This hypothesis makes use of the concept of droplets from seeds, the fundamentals of the adhesive properties of droplets, and a set of droplet characteristics. Fundamentals underlying the droplet formation from nanoparticle seeds under various physicochemical and thermodynamic conditions have been articulated. A model of thermodynamic imbalance of seeds at the growth temperature has been formulated. The dependence of thermodynamic imbalance on parameters such as surface energy, temperature, seed dimension, etc. has been described. The role of thermodynamic imbalance of seeds and of the foreign element catalytic agent (FECA) on NMT growth has been examined. Three different NMT growths, namely, FECA-free NMT growth; FECA-mediated non-eutectic NMT growth; and FECA-mediated eutectic NMT growth, have been considered. FECA-free NMT growth, and non-eutectic but FECA-mediated NMT growth, have been assumed to involve nanopores, grains, and grain boundaries in the seed. The basic science of all the NMT growths utilizes the concept of the creation of tiny component droplets (CODs). Extensive evidential (experimental and theoretical) demonstration of the hypothesis has been put forth. Both theoretical and experimental results lend support to the hypothesis. Calculated results address the roles of both the FECA-mediated and FECA-free droplets for NMT growths. The basics of multiple nucleation and biphasic structures have been spelled out. Possible relationship between the activation energy and the precursor decomposition on the droplet surface at the lowest possible temperature has been elucidated. The differences between the eutectic and no-eutectic seeds, the

  3. On Principle and Practice in General Education: A Bibliography of Earl J. McGrath. Public Administration Series: Bibliography P-1104.

    ERIC Educational Resources Information Center

    Quay, Richard H., Comp.

    A bibliography of approximately 160 materials authored, coauthored, or edited by Earl J. McGrath from 1931 through 1980 on principle and practice in general education is presented. Specific topics include the following: student enrollments at church-related colleges; values and American higher education; careers, values, and general education; the…

  4. Over-constraints and a unified mobility method for general spatial mechanisms Part 2: Application of the principle

    NASA Astrophysics Data System (ADS)

    Lu, Wenjuan; Zeng, Daxing; Huang, Zhen

    2016-01-01

    The pre-research on mobility analysis presented a unified-mobility formula and a methodology based on reciprocal screw theory by HUANG, which focused on classical and modern parallel mechanisms. However its range of application needs to further extend to general multi-loop spatial mechanism. This kind of mechanism is not only more complex in structure but also with strong motion coupling among loops, making the mobility analysis even more complicated, and the relevant research has long been ignored. It is focused on how to apply the new principle for general spatial mechanism to those various multi-loop spatial mechanisms, and some new meaningful knowledge is further found. Several typical examples of the general multi-loop spatial mechanisms with motion couple even strong motion couple are considered. These spatial mechanisms include different closing way: over-constraint appearing in rigid closure, in movable closure, and in dynamic closure as well; these examples also include two different new methods to solve this kind of issue: the way to recognize over-constraints by analyzing relative movement between two connected links and by constructing a virtual loop to recognize over-constraints. In addition, over-constraint determination tabulation is brought to analyze the motion couple. The researches above are all based upon the screw theory. All these multi-loop spatial mechanisms with different kinds of structures can completely be solved by following the directions and examples, and the new mobility theory based on the screw theory is also proved to be valid. This study not only enriches and develops the theory and makes the theory more universal, but also has a special meaning for innovation in mechanical engineering.

  5. First-principles local density approximation+U and generalized gradient approximation+U study of plutonium oxides

    NASA Astrophysics Data System (ADS)

    Sun, Bo; Zhang, Ping; Zhao, Xian-Geng

    2008-02-01

    The electronic structure and properties of PuO2 and Pu2O3 have been studied from first principles by the all-electron projector-augmented-wave method. The local density approximation+U and the generalized gradient approximation+U formalisms have been used to account for the strong on-site Coulomb repulsion among the localized Pu 5f electrons. We discuss how the properties of PuO2 and Pu2O3 are affected by the choice of U as well as the choice of exchange-correlation potential. Also, oxidation reaction of Pu2O3, leading to formation of PuO2, and its dependence on U and exchange-correlation potential have been studied. Our results show that by choosing an appropriate U, it is promising to correctly and consistently describe structural, electronic, and thermodynamic properties of PuO2 and Pu2O3, which enable the modeling of redox process involving Pu-based materials possible.

  6. Qualitative uncertainty principles for the generalized Fourier transform associated to a Dunkl type operator on the real line

    NASA Astrophysics Data System (ADS)

    Mejjaoli, Hatem; Trimèche, Khalifa

    2016-06-01

    In this paper, we prove various mathematical aspects of the qualitative uncertainty principle, including Hardy's, Cowling-Price's theorem, Morgan's theorem, Beurling, Gelfand-Shilov, Miyachi theorems.

  7. Equivalence principles and electromagnetism

    NASA Technical Reports Server (NTRS)

    Ni, W.-T.

    1977-01-01

    The implications of the weak equivalence principles are investigated in detail for electromagnetic systems in a general framework. In particular, it is shown that the universality of free-fall trajectories (Galileo weak equivalence principle) does not imply the validity of the Einstein equivalence principle. However, the Galileo principle plus the universality of free-fall rotation states does imply the Einstein principle.

  8. Transmembrane Communication: General Principles and Lessons from the Structure and Function of the M2 Proton Channel, K+ Channels, and Integrin Receptors

    PubMed Central

    Grigoryan, Gevorg; Moore, David T.; DeGrado, William F.

    2013-01-01

    Signal transduction across biological membranes is central to life. This process generally happens through communication between different domains and hierarchical coupling of information. Here, we review structural and thermodynamic principles behind transmembrane (TM) signal transduction and discuss common themes. Communication between signaling domains can be understood in terms of thermodynamic and kinetic principles, and complex signaling patterns can arise from simple wiring of thermodynamically coupled domains. We relate this to functions of several signal transduction systems: the M2 proton channel from influenza A virus, potassium channels, integrin receptors, and bacterial kinases. We also discuss key features in the structural rearrangements responsible for signal transduction in these systems. PMID:21548783

  9. Measurement scales in clinical research of the upper extremity, part 1: general principles, measures of general health, pain, and patient satisfaction.

    PubMed

    Badalamente, Marie; Coffelt, Laureen; Elfar, John; Gaston, Glenn; Hammert, Warren; Huang, Jerry; Lattanza, Lisa; Macdermid, Joy; Merrell, Greg; Netscher, David; Panthaki, Zubin; Rafijah, Greg; Trczinski, Douglas; Graham, Brent

    2013-02-01

    Measurement is a fundamental cornerstone in all aspects of scientific discovery, including clinical research. To be useful, measurement instruments must meet several key criteria, the most important of which are satisfactory reliability, validity, and responsiveness. Part 1 of this article reviews the general concepts of measurement instruments and describes the measurement of general health, pain, and patient satisfaction. PMID:23351912

  10. Application of HACCP principles to control visitor health threats on dairy farms open to the general public.

    PubMed

    Barten, M; Noordhuizen, J P M; Lipman, L J A

    2008-10-01

    An increasing number of Dutch dairy farmers have diversified their activities, often opening their farm up to visitors (tourist accommodation, farm shop, contact with livestock, etc). It is essential to prevent these visitors from having accidents or becoming ill, which could result in financial claims and might harm the reputation of the agricultural sector. This article describes how the hazard analysis critical control points concept and principles (HACCP) can be applied to these activities and integrated with on-farm operational herd health and production management programmes. PMID:18947047

  11. An extremum principle for computation of the zone of tooth contact and generalized transmission error of spiral bevel gears

    NASA Technical Reports Server (NTRS)

    Mark, W. D.

    1988-01-01

    For a given set of forces transmitted by the gears, each of the three components of the generalized transmission error of spiral bevel gears is shown to be stationary with respect to small independent variations in the positions of the endpoints of the lines of tooth contact about their true values. The tangential generalized transmission error component is shown to take on a minimum value at the true endpoint positions. A computational procedure based on the method of steepest descent is described for computing the true line of contact endpoint positions and the three components of the generalized transmission error. A method for computing the Fourier series coefficients of the tooth meshing harmonics of the three generalized transmission error components also is provided.

  12. Understanding the low-loss mechanism of general organic-inorganic perovskites from first-principles calculation

    NASA Astrophysics Data System (ADS)

    Li, Dan; Meng, Jingjing; Niu, Yuan; Zhao, Hongmin; Liang, Chunjun

    2015-05-01

    To understand the low-loss mechanism of organic-inorganic perovskites, the electronic structures of nine halide perovskites were investigated by first principle methods. We provide evidence that spatial separation significantly influences the recombination rate of electrons and holes. For AMPbI3-1, AMPbI3-2, FMPbI3-1, FMPbI3-2, and FAPbI3, the considerable remaining charge density localized at the organic cations in addition to a part of charge density of CBM localized at Pb atoms, leading to very few hopping with the surrounding inorganic matrix and further reducing the recombination rate of the carrier. Excellent optical absorption properties were found for all calculated APbI3 perovskites.

  13. First-principles calculation of defect free energies: General aspects illustrated in the case of bcc Fe

    NASA Astrophysics Data System (ADS)

    Murali, D.; Posselt, M.; Schiwarth, M.

    2015-08-01

    Modeling of nanostructure evolution in solids requires comprehensive data on the properties of defects such as the vacancy and foreign atoms. Since most processes occur at elevated temperatures, not only the energetics of defects in the ground state, but also their temperature-dependent free energies must be known. The first-principles calculation of contributions of phonon and electron excitations to free formation, binding, and migration energies of defects is illustrated in the case of bcc Fe. First of all, the ground-state properties of the vacancy, the foreign atoms Cu, Y, Ti, Cr, Mn, Ni, V, Mo, Si, Al, Co, O, and the O-vacancy pair are determined under constant volume (CV) as well as zero-pressure (ZP) conditions, and relations between the results of both kinds of calculations are discussed. Second, the phonon contribution to defect free energies is calculated within the harmonic approximation using the equilibrium atomic positions determined in the ground state under CV and ZP conditions. In most cases, the ZP-based free formation energy decreases monotonously with temperature, whereas for CV-based data both an increase and a decrease were found. The application of a quasiharmonic correction to the ZP-based data does not modify this picture significantly. However, the corrected data are valid under zero-pressure conditions at higher temperatures than in the framework of the purely harmonic approach. The difference between CV- and ZP-based data is mainly due to the volume change of the supercell since the relative arrangement of atoms in the environment of the defects is nearly identical in the two cases. A simple transformation similar to the quasiharmonic approach is found between the CV- and ZP-based frequencies. Therefore, it is not necessary to calculate these quantities and the corresponding defect free energies separately. In contrast to ground-state energetics, the CV- and ZP-based defect free energies do not become equal with increasing supercell

  14. Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1

    PubMed Central

    Rosenbloom, Daniel I. S.; Elliott, Oliver; Hill, Alison L.; Henrich, Timothy J.; Siliciano, Janet M.; Siliciano, Robert F.

    2015-01-01

    Limiting dilution assays are widely used in infectious disease research. These assays are crucial for current human immunodeficiency virus (HIV)-1 cure research in particular. In this study, we offer new tools to help investigators design and analyze dilution assays based on their specific research needs. Limiting dilution assays are commonly used to measure the extent of infection, and in the context of HIV they represent an essential tool for studying latency and potential curative strategies. Yet standard assay designs may not discern whether an intervention reduces an already miniscule latent infection. This review addresses challenges arising in this setting and in the general use of dilution assays. We illustrate the major statistical method for estimating frequency of infectious units from assay results, and we offer an online tool for computing this estimate. We recommend a procedure for customizing assay design to achieve desired sensitivity and precision goals, subject to experimental constraints. We consider experiments in which no viral outgrowth is observed and explain how using alternatives to viral outgrowth may make measurement of HIV latency more efficient. Finally, we discuss how biological complications, such as probabilistic growth of small infections, alter interpretations of experimental results. PMID:26478893

  15. General principles for the formation and proliferation of a wall-free (L-form) state in bacteria

    PubMed Central

    Mercier, Romain; Kawai, Yoshikazu; Errington, Jeff

    2014-01-01

    The peptidoglycan cell wall is a defining structural feature of the bacterial kingdom. Curiously, some bacteria have the ability to switch to a wall-free or ‘L-form’ state. Although known for decades, the general properties of L-forms are poorly understood, largely due to the lack of systematic analysis of L-forms in the molecular biology era. Here we show that inhibition of peptidoglycan precursor synthesis promotes the generation of L-forms from both Gram-positive and Gram-negative bacteria. We show that the L-forms generated have in common a mechanism of proliferation involving membrane blebbing and tubulation, which is dependent on an altered rate of membrane synthesis. Crucially, this mode of proliferation is independent of the essential FtsZ based division machinery. Our results suggest that the L-form mode of proliferation is conserved across the bacterial kingdom, reinforcing the idea that it could have been used in primitive cells, and opening up its use in the generation of synthetic cells. DOI: http://dx.doi.org/10.7554/eLife.04629.001 PMID:25358088

  16. Averting a Disaster with Groundwater Depletion in India: The General Case of Water Management Principles and Development (Invited)

    NASA Astrophysics Data System (ADS)

    Lall, U.

    2013-12-01

    Many countries, including the USA, China, and India are experiencing chronic groundwater depletion. In part this unsustainable water use results from climatic factors that reduce surface water availability and also the recharge to the aquifer system. However, a more critical factor is uncontrolled use for agriculture and energy and mineral processing. Interestingly in places such as India endowments have been politically created that lead to ever increasing use, through the provision of free energy for pumping. Reversing the situation is considered politically challenging, and the concept of metering and payment for what is essentially economic use of water is also considered difficult to apply. In this talk I use the Indian situation as a general example and discuss the role central planning strategies for demand and resource management can play recognizing the private action by millions of users as an inevitable tool that needs to be leveraged without necessarily the high transaction costs that come with monitoring and fee collection for monitored use. Specifically, targeting and stimulating potential cropping strategies and on farm water and energy management emerge as a choice in a difficult management environment. In a broader development context, I argue that the role of private sector aggregators in developing farm to market procurement strategies can play a role in both improving rural economies and providing a trajectory for more efficient water use through technology and crop choice.

  17. Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1.

    PubMed

    Rosenbloom, Daniel I S; Elliott, Oliver; Hill, Alison L; Henrich, Timothy J; Siliciano, Janet M; Siliciano, Robert F

    2015-12-01

    Limiting dilution assays are widely used in infectious disease research. These assays are crucial for current human immunodeficiency virus (HIV)-1 cure research in particular. In this study, we offer new tools to help investigators design and analyze dilution assays based on their specific research needs. Limiting dilution assays are commonly used to measure the extent of infection, and in the context of HIV they represent an essential tool for studying latency and potential curative strategies. Yet standard assay designs may not discern whether an intervention reduces an already miniscule latent infection. This review addresses challenges arising in this setting and in the general use of dilution assays. We illustrate the major statistical method for estimating frequency of infectious units from assay results, and we offer an online tool for computing this estimate. We recommend a procedure for customizing assay design to achieve desired sensitivity and precision goals, subject to experimental constraints. We consider experiments in which no viral outgrowth is observed and explain how using alternatives to viral outgrowth may make measurement of HIV latency more efficient. Finally, we discuss how biological complications, such as probabilistic growth of small infections, alter interpretations of experimental results. PMID:26478893

  18. Three-year-olds obey the sample size principle of induction: the influence of evidence presentation and sample size disparity on young children's generalizations.

    PubMed

    Lawson, Chris A

    2014-07-01

    Three experiments with 81 3-year-olds (M=3.62years) examined the conditions that enable young children to use the sample size principle (SSP) of induction-the inductive rule that facilitates generalizations from large rather than small samples of evidence. In Experiment 1, children exhibited the SSP when exemplars were presented sequentially but not when exemplars were presented simultaneously. Results from Experiment 3 suggest that the advantage of sequential presentation is not due to the additional time to process the available input from the two samples but instead may be linked to better memory for specific individuals in the large sample. In addition, findings from Experiments 1 and 2 suggest that adherence to the SSP is mediated by the disparity between presented samples. Overall, these results reveal that the SSP appears early in development and is guided by basic cognitive processes triggered during the acquisition of input. PMID:24439115

  19. Generalization of the k-moment method using the maximum entropy principle. Application to the NBKM and full spectrum SLMB gas radiation models

    NASA Astrophysics Data System (ADS)

    André, Frédéric; Vaillon, Rodolphe

    2012-08-01

    The k-moment method is generalized by applying the maximum entropy principle to get several estimates of the k-distribution function on any kind of spectral interval as a function of the first two moments of the absorption coefficient. Corresponding formulations of the blackbody weighted band averaged transmission function of a gaseous uniform path are obtained. Different constraints involving the first and second order positive, first order negative and logarithmic moments are introduced together with a physical meaning whenever it is possible. Different sets of these constraints are considered to get maximum entropy estimates of the distributions functions: the Dirac, exponential, Gamma, inverse Gaussian and reciprocal inverse Gaussian k-distribution functions. Analytical formulas are provided for each of these distributions and for their associated transmission function, as a function of the mean and variance of the absorption coefficient. The methodology can be applied considering any spectral interval: narrow, wide, the full spectrum, continuous or not. Thus the resulting associated transmission and cumulative k-distribution functions can be utilized in the frame of a large variety of gas radiation models. Hence the k-moment method using the maximum entropy principle is assessed in the frame of the NBKM and full spectrum SLMB gas radiation models. A series of test cases implying comparisons with reference Line-by-Line results exhibits which maximum entropy k-distributions are likely to give the best estimations of narrow band or total emitted intensities, curves-of-growth of the total emission function and full spectrum cumulative k-distribution functions. In particular, the inverse Gaussian and Gamma k-distributions seem most of the time to perform very well.

  20. Bernoulli's Principle

    ERIC Educational Resources Information Center

    Hewitt, Paul G.

    2004-01-01

    Some teachers have difficulty understanding Bernoulli's principle particularly when the principle is applied to the aerodynamic lift. Some teachers favor using Newton's laws instead of Bernoulli's principle to explain the physics behind lift. Some also consider Bernoulli's principle too difficult to explain to students and avoid teaching it…

  1. Earth's Earliest Ecosystems in the C: The Use of Microbial Mats to Demonstrate General Principles of Scientific Inquiry and Microbial Ecology

    NASA Technical Reports Server (NTRS)

    Bebout, Brad M.; Bucaria, Robin

    2006-01-01

    Microbial mats are living examples of the most ancient biological communities on Earth. As Earth's earliest ecosystems, they are centrally important to understanding the history of life on our planet and are useful models for the search for life elsewhere. As relatively compact (but complete) ecosystems, microbial mats are also extremely useful for educational activities. Mats may be used to demonstrate a wide variety of concepts in general and microbial ecology, including the biogeochemical cycling of elements, photosynthesis and respiration, and the origin of the Earth's present oxygen containing atmosphere. Microbial mats can be found in a number of common environments accessible to teachers, and laboratory microbial mats can be constructed using materials purchased from biological supply houses. With funding from NASA's Exobiology program, we have developed curriculum and web-based activities centered on the use of microbial mats as tools for demonstrating general principles in ecology, and the scientific process. Our web site (http://microbes.arc.nasa.gov) includes reference materials, lesson plans, and a "Web Lab", featuring living mats maintained in a mini-aquarium. The site also provides information as to how research on microbial mats supports NASA's goals, and various NASA missions. A photo gallery contains images of mats, microscopic views of the organisms that form them, and our own research activities. An animated educational video on the web site uses computer graphic and video microscopy to take students on a journey into a microbial mat. These activities are targeted to a middle school audience and are aligned with the National Science Standards.

  2. Guiding Principles for Evaluators.

    ERIC Educational Resources Information Center

    Shadish, William R., Ed.; And Others

    1995-01-01

    The 12 articles (including an index) of this theme issue are devoted to documenting and critiquing the American Evaluation Association's "Guiding Principles for Evaluators," a code of ethics and standards. The development of these principles is traced, and their strengths and weaknesses are analyzed at general and specific levels. (SLD)

  3. 7 CFR 3430.31 - Guiding principles.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ASSISTANCE PROGRAMS-GENERAL AWARD ADMINISTRATIVE PROVISIONS Pre-award: Application Review and Evaluation § 3430.31 Guiding principles. The guiding principle for Federal assistance application review...

  4. Earth's Earliest Ecosystems in the Classroom: The Use of Microbial Mats to Illustrate and Demonstrate General Principles of Scientific Inquiry and Microbial Ecology

    NASA Astrophysics Data System (ADS)

    Bebout, B. M.; Bucaria, R.

    2004-12-01

    Microbial mats are living examples of the most ancient biological communities on Earth. As Earth's earliest ecosystems, they are centrally important to understanding the history of life on our planet and are useful models for the search for life elsewhere. As relatively small (but complete) ecosystems, microbial mats are also extremely useful for educational activities. Mats may be used to demonstrate a wide variety of concepts in general and microbial ecology, including the biogeochemical cycling of elements, photosynthesis and respiration, and the and the origin of the Earth's present oxygen containing atmosphere. Microbial mats can be found in a number of common environments accessible to teachers, and laboratory microbial mats can even be constructed using materials purchased from biological supply houses. With funding from NASA's Exobiology program, provided as a supplement to our research funding, we are developing curriculum and web-based activities centered on the use of microbial mats as tools for demonstrating general principles in ecology, and the scientific process. A web site with useful background information and links is now on-line. The curriculum, now in the pilot phase, is an integrated module having Science, Math and Language Art threads. A "Web Lab", featuring living mats maintained in a mini-aquarium, and complete with remotely-operable instrumentation not commonly available in classrooms, will be available to classrooms over the Internet. Using that system, the responses of the mat community to changes in environmental parameters, (e.g., light, pH, flow, and temperature) can be monitored using microsensors. Students will be able to develop hypotheses and propose experiments in the Web Lab to test them. Data from these experiments will be posted in real time and students will be able to collect the data, analyze it, and post results and conclusions back to the web page in a true implementation of the scientific inquiry process. The web site

  5. Buridan's Principle

    NASA Astrophysics Data System (ADS)

    Lamport, Leslie

    2012-08-01

    Buridan's principle asserts that a discrete decision based upon input having a continuous range of values cannot be made within a bounded length of time. It appears to be a fundamental law of nature. Engineers aware of it can design devices so they have an infinitessimal probability of not making a decision quickly enough. Ignorance of the principle could have serious consequences.

  6. Principled Narrative

    ERIC Educational Resources Information Center

    MacBeath, John; Swaffield, Sue; Frost, David

    2009-01-01

    This article provides an overview of the "Carpe Vitam: Leadership for Learning" project, accounting for its provenance and purposes, before focusing on the principles for practice that constitute an important part of the project's legacy. These principles framed the dialogic process that was a dominant feature of the project and are presented,…

  7. Principles of Tendon Transfer.

    PubMed

    Wilbur, Danielle; Hammert, Warren C

    2016-08-01

    Tendon transfers provide a substitute, either temporary or permanent, when function is lost due to neurologic injury in stroke, cerebral palsy or central nervous system lesions, peripheral nerve injuries, or injuries to the musculotendinous unit itself. This article reviews the basic principles of tendon transfer, which are important when planning surgery and essential for an optimal outcome. In addition, concepts for coapting the tendons during surgery and general principles to be followed during the rehabilitation process are discussed. PMID:27387072

  8. The genetic difference principle.

    PubMed

    Farrelly, Colin

    2004-01-01

    In the newly emerging debates about genetics and justice three distinct principles have begun to emerge concerning what the distributive aim of genetic interventions should be. These principles are: genetic equality, a genetic decent minimum, and the genetic difference principle. In this paper, I examine the rationale of each of these principles and argue that genetic equality and a genetic decent minimum are ill-equipped to tackle what I call the currency problem and the problem of weight. The genetic difference principle is the most promising of the three principles and I develop this principle so that it takes seriously the concerns of just health care and distributive justice in general. Given the strains on public funds for other important social programmes, the costs of pursuing genetic interventions and the nature of genetic interventions, I conclude that a more lax interpretation of the genetic difference principle is appropriate. This interpretation stipulates that genetic inequalities should be arranged so that they are to the greatest reasonable benefit of the least advantaged. Such a proposal is consistent with prioritarianism and provides some practical guidance for non-ideal societies--that is, societies that do not have the endless amount of resources needed to satisfy every requirement of justice. PMID:15186680

  9. 48 CFR 49.113 - Cost principles.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Cost principles. 49.113... TERMINATION OF CONTRACTS General Principles 49.113 Cost principles. The cost principles and procedures in the..., negotiating, or determining costs relevant to termination settlements under contracts with other...

  10. 48 CFR 49.113 - Cost principles.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Cost principles. 49.113 Section 49.113 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS General Principles 49.113 Cost principles. The cost principles and procedures in...

  11. 48 CFR 49.113 - Cost principles.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Cost principles. 49.113 Section 49.113 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS General Principles 49.113 Cost principles. The cost principles and procedures in...

  12. 48 CFR 49.113 - Cost principles.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Cost principles. 49.113 Section 49.113 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS General Principles 49.113 Cost principles. The cost principles and procedures in...

  13. 48 CFR 49.113 - Cost principles.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Cost principles. 49.113 Section 49.113 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS General Principles 49.113 Cost principles. The cost principles and procedures in...

  14. Fermat's Principle Revisited.

    ERIC Educational Resources Information Center

    Kamat, R. V.

    1991-01-01

    A principle is presented to show that, if the time of passage of light is expressible as a function of discrete variables, one may dispense with the more general method of the calculus of variations. The calculus of variations and the alternative are described. The phenomenon of mirage is discussed. (Author/KR)

  15. Earth's Earliest Ecosystems in the Classroom: The Use of Microbial Mats to Teach General Principles in Microbial Ecology, and Scientific Inquiry

    NASA Technical Reports Server (NTRS)

    Beboutl, Brad M.; Bucaria, Robin

    2004-01-01

    Microbial mats are living examples of the most ancient biological communities on earth, and may also be useful models for the search for life elsewhere. They are centrally important to Astrobiology. In this lecture, we will present an introduction to microbial mats, as well as an introduction to our web-based educational module on the subject of microbial ecology, featuring living mats maintained in a mini "Web Lab" complete with remotely-operable instrumentation. We have partnered with a number of outreach specialists in order to produce an informative and educational web-based presentation, aspects of which will be exported to museum exhibits reaching a wide audience. On our web site, we will conduct regularly scheduled experimental manipulations, linking the experiments to our research activities, and demonstrating fundamental principles of scientific research.

  16. Yielding Unexpected Results: Precipitation of Ba[subscript3](PO[subscript4])[subscript2] and Implications for Teaching Solubility Principles in the General Chemistry Curriculum

    ERIC Educational Resources Information Center

    Hazen, Jeffery L.; Cleary, David A.

    2014-01-01

    Precipitation of barium phosphate from aqueous solutions of a barium salt and a phosphate salt forms the basis for a number of conclusions drawn in general chemistry. For example, the formation of a solid white precipitate is offered as evidence that barium phosphate is insoluble. Furthermore, analysis of the supernatant is used to illustrate the…

  17. Principles of Instructed Language Learning

    ERIC Educational Resources Information Center

    Ellis, Rod

    2005-01-01

    This article represents an attempt to draw together findings from a range of second language acquisition studies in order to formulate a set of general principles for language pedagogy. These principles address such issues as the nature of second language (L2) competence (as formulaic and rule-based knowledge), the contributions of both focus on…

  18. Programming of enzyme specificity by substrate mimetics: investigations on the Glu-specific V8 protease reveals a novel general principle of biocatalysis.

    PubMed

    Wehofsky, N; Bordusa, F

    1999-01-25

    In this paper the universal validity of the substrate mimetic concept in enzymatic C-N ligations was expanded to anionic leaving groups based on the specificity determinants of Glu-specific endopeptidase from Staphylococcus aureus (V8 protease). In an empirical way a specific mimetic moiety was designed from simple structure-function relationship studies. The general function of the newly developed substrate mimetics to serve as an artificial recognition site for V8 protease have been examined by hydrolysis kinetic studies. Enzymatic peptide syntheses qualify the strategy of substrate mimetics as a powerful concept for programming the enzyme specificity in the direction of a more universal application of enzymes in the general area of biocatalysis. PMID:9989609

  19. American Evaluation Association Guiding Principles for Evaluators

    SciTech Connect

    2009-01-18

    Five principles developed by American Evaluation Associ intended to guide professional practice of evaluators & to inform evaluation clients and the general public about principles they can expect to be upheld by professional evaluators.

  20. Phraseology and Second Language Proficiency.

    ERIC Educational Resources Information Center

    Howarth, Peter

    1998-01-01

    Discusses, in the context of second-language learning, the definition of collocations in English and major approaches to linguistic description of prefabricated language. Presents data from a study comparing use of specific lexical collocations (phrases) by native speakers (based on existing language corpus) and learners of English (data drawn…

  1. Direct Linearization and Adjoint Approaches to Evaluation of Atmospheric Weighting Functions and Surface Partial Derivatives: General Principles, Synergy and Areas of Application

    NASA Technical Reports Server (NTRS)

    Ustino, Eugene A.

    2006-01-01

    This slide presentation reviews the observable radiances as functions of atmospheric parameters and of surface parameters; the mathematics of atmospheric weighting functions (WFs) and surface partial derivatives (PDs) are presented; and the equation of the forward radiative transfer (RT) problem is presented. For non-scattering atmospheres this can be done analytically, and all WFs and PDs can be computed analytically using the direct linearization approach. For scattering atmospheres, in general case, the solution of the forward RT problem can be obtained only numerically, but we need only two numerical solutions: one of the forward RT problem and one of the adjoint RT problem to compute all WFs and PDs we can think of. In this presentation we discuss applications of both the linearization and adjoint approaches

  2. Computational principles of memory.

    PubMed

    Chaudhuri, Rishidev; Fiete, Ila

    2016-03-01

    The ability to store and later use information is essential for a variety of adaptive behaviors, including integration, learning, generalization, prediction and inference. In this Review, we survey theoretical principles that can allow the brain to construct persistent states for memory. We identify requirements that a memory system must satisfy and analyze existing models and hypothesized biological substrates in light of these requirements. We also highlight open questions, theoretical puzzles and problems shared with computer science and information theory. PMID:26906506

  3. Gamma-Ray Telescope and Uncertainty Principle

    ERIC Educational Resources Information Center

    Shivalingaswamy, T.; Kagali, B. A.

    2012-01-01

    Heisenberg's Uncertainty Principle is one of the important basic principles of quantum mechanics. In most of the books on quantum mechanics, this uncertainty principle is generally illustrated with the help of a gamma ray microscope, wherein neither the image formation criterion nor the lens properties are taken into account. Thus a better…

  4. Principles of Natural Photosynthesis.

    PubMed

    Krewald, Vera; Retegan, Marius; Pantazis, Dimitrios A

    2016-01-01

    Nature relies on a unique and intricate biochemical setup to achieve sunlight-driven water splitting. Combined experimental and computational efforts have produced significant insights into the structural and functional principles governing the operation of the water-oxidizing enzyme Photosystem II in general, and of the oxygen-evolving manganese-calcium cluster at its active site in particular. Here we review the most important aspects of biological water oxidation, emphasizing current knowledge on the organization of the enzyme, the geometric and electronic structure of the catalyst, and the role of calcium and chloride cofactors. The combination of recent experimental work on the identification of possible substrate sites with computational modeling have considerably limited the possible mechanistic pathways for the critical O-O bond formation step. Taken together, the key features and principles of natural photosynthesis may serve as inspiration for the design, development, and implementation of artificial systems. PMID:26099285

  5. Common Principles and Multiculturalism

    PubMed Central

    Zahedi, Farzaneh; Larijani, Bagher

    2009-01-01

    Judgment on rightness and wrongness of beliefs and behaviors is a main issue in bioethics. Over centuries, big philosophers and ethicists have been discussing the suitable tools to determine which act is morally sound and which one is not. Emerging the contemporary bioethics in the West has resulted in a misconception that absolute westernized principles would be appropriate tools for ethical decision making in different cultures. We will discuss this issue by introducing a clinical case. Considering various cultural beliefs around the world, though it is not logical to consider all of them ethically acceptable, we can gather on some general fundamental principles instead of going to the extremes of relativism and absolutism. Islamic teachings, according to the presented evidence in this paper, fall in with this idea. PMID:23908720

  6. 16 CFR 260.6 - General principles.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... Example 4: A package of paper coffee filters is labeled “These filters were made with a chlorine-free..., but still significant, amount of the same harmful byproducts associated with chlorine bleaching. The... chlorine bleaching. A claim, however, that the filters were “bleached with a process that...

  7. General principles of magnetic fusion confinement

    SciTech Connect

    Hogan, J.T.

    1980-01-01

    A few of the areas are described in which there is close interaction between atomic/molecular (A and M) and magnetic fusion physics. The comparisons between predictions of neoclassical transport theory and experiment depend on knowledge of ionization and recombination rate coefficients. Modeling of divertor/scrapeoff plasmas requires better low energy charge exchange cross sections for H + A/sup n+/ collisions. The range of validity of neutral beam trapping cross sections must be broadened, both to encompass the energies typical of present injection experiments and to deal with the problem of prompt trapping of highly excited beam atoms at high energy. Plasma fueling models present certain anomalies that could be resolved by calculation and measurement of low energy (<1 keV) charge exchange cross sections.

  8. 16 CFR 260.3 - General principles.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the ability to recycle the product, the claim would be deceptive. Example 1: A plastic package... the claim does not make clear whether it refers to the plastic package or the shower curtain, the... our previous bathroom tiles.” Example 2: An advertiser claims that “our plastic diaper liner has...

  9. 16 CFR 260.3 - General principles.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... the ability to recycle the product, the claim would be deceptive. Example 1: A plastic package... the claim does not make clear whether it refers to the plastic package or the shower curtain, the... our previous bathroom tiles.” Example 2: An advertiser claims that “our plastic diaper liner has...

  10. 16 CFR 260.6 - General principles.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... of recycled material. Example 2: A trash bag is labeled “recyclable” without qualification. Because trash bags will ordinarily not be separated out from other trash at the landfill or incinerator...

  11. 31 CFR 29.341 - General principle.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... formula that applies under the plan in effect on June 29, 1997, and the actual retirement age, including any applicable age reduction, based on the age at actual retirement); (b) The service that became... CERTAIN DISTRICT OF COLUMBIA RETIREMENT PROGRAMS Split Benefits Calculation of the Amount of...

  12. 16 CFR 260.6 - General principles.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the product, then the claim would be deceptive. Example 1: A box of aluminum foil is labeled with the... deceptive if any part of either the box or the foil, other than minor, incidental components, cannot be... be a minor, incidental component of the package, the claim is not deceptive. Similarly, it would...

  13. [Permanent percutaneous electric connection. General principles].

    PubMed

    Sabin, P; Labbé, D; Levillain, D; Cazin, L; Caston, J

    1997-01-01

    The Swedes for more than twenty years, and the Germans for over five years have been able to maintain inert or active prostheses with permanent percutaneous connections, thanks to the dependable and proven material and techniques of extraoral implants. The significant improvement extra-oral implants have brought about is not only in a new therapeutic approach to the treatment of important facial defects or transmission deafness; it is also because for some twenty old years now, the few millimeter wide cylinders of Titanium, the affixed on the implants, have crossed the cutaneous barrier for extended periods without complications. The percutaneous abutment thus creates a permanent communication between the interior and the exterior of the organism. If the abutment, instead of simply carrying a Maxillo-Facial Prosthesis or an auditive prosthesis, is modified by placing an electric conductor inside it, the simple "percutaneous peg" will turn out to be, in a way, a "percutaneous electric plug". By adapting classic "mechanical" abutments and implants, authors have created a Permanent Percutaneous Electric Connection (PPEC) which has been successfully experimented on rabbits to record EEG. Clinical applications on humans would make it possible either to receive "bio-electrical information" coming from within the organism, or to send electrical energy into the organism. This last application opens vast perspectives of improvement both in diagnosis and therapy in many fields. PMID:9687654

  14. 21 CFR 502.5 - General principles.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... finished product (i.e., weight/weight in the case of solids, or volume/volume in the case of liquids). (2... boldface print or type in distinct contrast to other printed or graphic matter, and in a height not less than the larger of the following alternatives: (i) Not less than one-sixteenth inch in height...

  15. 21 CFR 102.5 - General principles.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... quantity in the finished product (i.e., weight/weight in the case of solids, or volume/volume in the case..., and in a height not less than the larger of the following alternatives: (i) Not less than one-sixteenth inch in height on packages having a principal display panel with an area of 5 square inches...

  16. 21 CFR 102.5 - General principles.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... quantity in the finished product (i.e., weight/weight in the case of solids, or volume/volume in the case..., and in a height not less than the larger of the following alternatives: (i) Not less than one-sixteenth inch in height on packages having a principal display panel with an area of 5 square inches...

  17. Chemoprevention--history and general principles.

    PubMed

    Wu, Xiangwei; Patterson, Sherri; Hawk, Ernest

    2011-08-01

    Our current understanding of tumourigenesis suggests that cancer develops as a series of cumulative genetic and epigenetic derangements across time culminating in a clone of cells differing from its population of origin in terms of cellular identity, growth control, and its contextual relationship to its environment. Our increasing knowledge of the timing, sequence, frequency, and specific implications of these changes provides unique opportunities for earlier identification of aberrations and preventive interventions. Here we discuss the fundamentals of cancer prevention including the targets, cohorts, agents, endpoints, mechanistic biomarkers, designs, and strategies employed in preventive drug development. There have been many notable successes in this field such as the identification and development of tamoxifen and raloxifene for breast cancer risk reduction, instillational BCG and valrubicin for treatment of preinvasive bladder cancer, and a variety of topical and systemic agents that effectively treat preinvasive neoplastic lesions of the skin. A variety of null or negative developmental endeavours have occurred as well, including trials of beta-carotene for lung cancer prevention, nutritional modifications for colorectal adenoma prevention, and most recently, selenium and alpha-tocopherol for prostate cancer prevention. A third category of prevention trials can be summarized as investigationally successful, but not achieving regulatory success. The development of finasteride and dutasteride for prostate cancer prevention, and celecoxib for colorectal neoplasia prevention fall into this category. In less than four decades, cancer chemoprevention has transformed from a concept to an achievable reality. PMID:22122762

  18. 12 CFR 330.3 - General principles.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Board of Governors of the Federal Reserve System in Regulation D (12 CFR 204.8(a)(2)), or in any... buying rates for cable transfers”) quoted for major currencies by the Federal Reserve Bank of New York...

  19. 21 CFR 102.5 - General principles.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., in as simple and direct terms as possible, the basic nature of the food or its characterizing.... Each class or subclass of food shall be given its own common or usual name that states, in clear terms, what it is in a way that distinguishes it from different foods. (b) The common or usual name of a...

  20. 12 CFR 330.3 - General principles.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Board of Governors of the Federal Reserve System in Regulation D (12 CFR 204.8(a)(2)), or in any... of the Pacific Islands, and the Virgin Islands, is not a deposit for the purposes of this part....

  1. 12 CFR 330.3 - General principles.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Board of Governors of the Federal Reserve System in Regulation D (12 CFR 204.8(a)(2)), or in any... of the Pacific Islands, and the Virgin Islands, is not a deposit for the purposes of this part....

  2. Equivalence Principle and Gravitational Redshift

    SciTech Connect

    Hohensee, Michael A.; Chu, Steven; Mueller, Holger; Peters, Achim

    2011-04-15

    We investigate leading order deviations from general relativity that violate the Einstein equivalence principle in the gravitational standard model extension. We show that redshift experiments based on matter waves and clock comparisons are equivalent to one another. Consideration of torsion balance tests, along with matter-wave, microwave, optical, and Moessbauer clock tests, yields comprehensive limits on spin-independent Einstein equivalence principle-violating standard model extension terms at the 10{sup -6} level.

  3. Principles of Quantum Mechanics

    NASA Astrophysics Data System (ADS)

    Landé, Alfred

    2013-10-01

    Preface; Introduction: 1. Observation and interpretation; 2. Difficulties of the classical theories; 3. The purpose of quantum theory; Part I. Elementary Theory of Observation (Principle of Complementarity): 4. Refraction in inhomogeneous media (force fields); 5. Scattering of charged rays; 6. Refraction and reflection at a plane; 7. Absolute values of momentum and wave length; 8. Double ray of matter diffracting light waves; 9. Double ray of matter diffracting photons; 10. Microscopic observation of ρ (x) and σ (p); 11. Complementarity; 12. Mathematical relation between ρ (x) and σ (p) for free particles; 13. General relation between ρ (q) and σ (p); 14. Crystals; 15. Transition density and transition probability; 16. Resultant values of physical functions; matrix elements; 17. Pulsating density; 18. General relation between ρ (t) and σ (є); 19. Transition density; matrix elements; Part II. The Principle of Uncertainty: 20. Optical observation of density in matter packets; 21. Distribution of momenta in matter packets; 22. Mathematical relation between ρ and σ; 23. Causality; 24. Uncertainty; 25. Uncertainty due to optical observation; 26. Dissipation of matter packets; rays in Wilson Chamber; 27. Density maximum in time; 28. Uncertainty of energy and time; 29. Compton effect; 30. Bothe-Geiger and Compton-Simon experiments; 31. Doppler effect; Raman effect; 32. Elementary bundles of rays; 33. Jeans' number of degrees of freedom; 34. Uncertainty of electromagnetic field components; Part III. The Principle of Interference and Schrödinger's equation: 35. Physical functions; 36. Interference of probabilities for p and q; 37. General interference of probabilities; 38. Differential equations for Ψp (q) and Xq (p); 39. Differential equation for фβ (q); 40. The general probability amplitude Φβ' (Q); 41. Point transformations; 42. General theorem of interference; 43. Conjugate variables; 44. Schrödinger's equation for conservative systems; 45. Schr

  4. Information and communication on risks related to medications and proper use of medications for healthcare professionals and the general public: precautionary principle, risk management, communication during and in the absence of crisis situations.

    PubMed

    Molimard, Mathieu; Bernaud, Corine; Lechat, Philippe; Bejan-Angoulvant, Theodora; Benattia, Cherif; Benkritly, Amel; Braunstein, David; Cabut, Sandrine; David, Nadine; Fourrier-Réglat, Annie; Gallet, Benoit; Gersberg, Marta; Goni, Sylvia; Jolliet, Pascale; Lamarque-Garnier, Véronique; Le Jeunne, Claire; Leurs, Irina; Liard, François; Malbezin, Muriel; Micallef, Joelle; Nguon, Marina

    2014-01-01

    Recent drug crises have highlighted the complexity, benefits and risks of medication communication. The difficulty of this communication is due to the diversity of the sources of information and the target audience, the credibility of spokespersons, the difficulty to communicate on scientific uncertainties and the precautionary principle, which is influenced by variable perceptions and tolerances of the risk. Globally, there is a lack of training in risk management with a tendency of modern society to refuse even the slightest risk. Communication on medications is subject to regulatory or legal requirements, often uses tools and messages that are not adapted to the target audience and is often based on a poor knowledge of communication techniques. In order to improve this situation, the available information must be coordinated by reinforcing the unique medication information website and by coordinating communication between authorities by means of a single spokesperson. A particular effort must be made in the field of training in the proper use and risk of medications for both the general population and patients but also for healthcare professionals, by setting up a unified academic on-line teaching platform for continuing medical education on medications and their proper use. PMID:25099666

  5. "C.R.E.A.T.E."-ing Unique Primary-Source Research Paper Assignments for a Pleasure and Pain Course Teaching Neuroscientific Principles in a Large General Education Undergraduate Course.

    PubMed

    Bodnar, Richard J; Rotella, Francis M; Loiacono, Ilyssa; Coke, Tricia; Olsson, Kerstin; Barrientos, Alicia; Blachorsky, Lauren; Warshaw, Deena; Buras, Agata; Sanchez, Ciara M; Azad, Raihana; Stellar, James R

    2016-01-01

    A large (250 registrants) General Education lecture course, Pleasure and Pain, presented basic neuroscience principles as they related to animal and human models of pleasure and pain by weaving basic findings related to food and drug addiction and analgesic states with human studies examining empathy, social neuroscience and neuroeconomics. In its first four years, the course grade was based on weighted scores from two multiple-choice exams and a five-page review of three unique peer-reviewed research articles. Although well-registered and well-received, 18% of the students received Incomplete grades, primarily due to failing to submit the paper that went largely unresolved and eventually resulted in a failing grade. To rectify this issue, a modified version of the C.R.E.A.T.E. (Consider, Read, Elucidate hypotheses, Analyze and interpret data, Think of the next Experiment) method replaced the paper with eight structured assignments focusing on an initial general-topic article, the introduction-methods, and results-discussion of each of three related peer-review neuroscience-related articles, and a final summary. Compliance in completing these assignments was very high, resulting in only 11 INC grades out of 228 students. Thus, use of the C.R.E.A.T.E. method reduced the percentage of problematic INC grades from 18% to 4.8%, a 73% decline, without changing the overall grade distribution. Other analyses suggested the students achieved a deeper understanding of the scientific process using the C.R.E.A.T.E. method relative to the original term paper assignment. PMID:27385918

  6. “C.R.E.A.T.E.”-ing Unique Primary-Source Research Paper Assignments for a Pleasure and Pain Course Teaching Neuroscientific Principles in a Large General Education Undergraduate Course

    PubMed Central

    Bodnar, Richard J.; Rotella, Francis M.; Loiacono, Ilyssa; Coke, Tricia; Olsson, Kerstin; Barrientos, Alicia; Blachorsky, Lauren; Warshaw, Deena; Buras, Agata; Sanchez, Ciara M.; Azad, Raihana; Stellar, James R.

    2016-01-01

    A large (250 registrants) General Education lecture course, Pleasure and Pain, presented basic neuroscience principles as they related to animal and human models of pleasure and pain by weaving basic findings related to food and drug addiction and analgesic states with human studies examining empathy, social neuroscience and neuroeconomics. In its first four years, the course grade was based on weighted scores from two multiple-choice exams and a five-page review of three unique peer-reviewed research articles. Although well-registered and well-received, 18% of the students received Incomplete grades, primarily due to failing to submit the paper that went largely unresolved and eventually resulted in a failing grade. To rectify this issue, a modified version of the C.R.E.A.T.E. (Consider, Read, Elucidate hypotheses, Analyze and interpret data, Think of the next Experiment) method replaced the paper with eight structured assignments focusing on an initial general-topic article, the introduction-methods, and results-discussion of each of three related peer-review neuroscience-related articles, and a final summary. Compliance in completing these assignments was very high, resulting in only 11 INC grades out of 228 students. Thus, use of the C.R.E.A.T.E. method reduced the percentage of problematic INC grades from 18% to 4.8%, a 73% decline, without changing the overall grade distribution. Other analyses suggested the students achieved a deeper understanding of the scientific process using the C.R.E.A.T.E. method relative to the original term paper assignment. PMID:27385918

  7. Chemical Principles Revisited: Chemical Equilibrium.

    ERIC Educational Resources Information Center

    Mickey, Charles D.

    1980-01-01

    Describes: (1) Law of Mass Action; (2) equilibrium constant and ideal behavior; (3) general form of the equilibrium constant; (4) forward and reverse reactions; (5) factors influencing equilibrium; (6) Le Chatelier's principle; (7) effects of temperature, changing concentration, and pressure on equilibrium; and (8) catalysts and equilibrium. (JN)

  8. Developmental Principles: Fact or Fiction

    PubMed Central

    Durston, A. J.

    2012-01-01

    While still at school, most of us are deeply impressed by the underlying principles that so beautifully explain why the chemical elements are ordered as they are in the periodic table, and may wonder, with the theoretician Brian Goodwin, “whether there might be equally powerful principles that account for the awe-inspiring diversity of body forms in the living realm”. We have considered the arguments for developmental principles, conclude that they do exist and have specifically identified features that may generate principles associated with Hox patterning of the main body axis in bilaterian metazoa in general and in the vertebrates in particular. We wonder whether this exercise serves any purpose. The features we discuss were already known to us as parts of developmental mechanisms and defining developmental principles (how, and at which level?) adds no insight. We also see little profit in the proposal by Goodwin that there are principles outside the emerging genetic mechanisms that need to be taken into account. The emerging developmental genetic hierarchies already reveal a wealth of interesting phenomena, whatever we choose to call them. PMID:22489210

  9. Fracture mechanics principles.

    PubMed

    Mecholsky, J J

    1995-03-01

    The principles of linear elastic fracture mechanics (LEFM) were developed in the 1950s by George Irwin (1957). This work was based on previous investigations of Griffith (1920) and Orowan (1944). Irwin (1957) demonstrated that a crack shape in a particular location with respect to the loading geometry had a stress intensity associated with it. He also demonstrated the equivalence between the stress intensity concept and the familiar Griffith criterion of failure. More importantly, he described the systematic and controlled evaluation of the toughness of a material. Toughness is defined as the resistance of a material to rapid crack propagation and can be characterized by one parameter, Kic. In contrast, the strength of a material is dependent on the size of the initiating crack present in that particular sample or component. The fracture toughness of a material is generally independent of the size of the initiating crack. The strength of any product is limited by the size of the cracks or defects during processing, production and handling. Thus, the application of fracture mechanics principles to dental biomaterials is invaluable in new material development, production control and failure analysis. This paper describes the most useful equations of fracture mechanics to be used in the failure analysis of dental biomaterials. PMID:8621030

  10. Principle of least wave change.

    PubMed

    Abramson, N

    1989-05-01

    Fermat's principle of least time has some well-known limitations. It does not, for example, apply to diffraction gratings and holograms, because it does not include the concept of waves. The substitution of least number of waves in flight for least time of flight and the addition of a term that is a function of the grating frequency result in a generalized principle. It is easy to remember because it is based on only the number of waves minus the number of grooves, and it would be especially useful when refraction and diffraction are combined, as, for example, in some holographic optical elements. PMID:2723846

  11. Kepler and Mach's Principle

    NASA Astrophysics Data System (ADS)

    Barbour, Julian

    The definitive ideas that led to the creation of general relativity crystallized in Einstein's thinking during 1912 while he was in Prague. At the centenary meeting held there to mark the breakthrough, I was asked to talk about earlier great work of relevance to dynamics done at Prague, above all by Kepler and Mach. The main topics covered in this chapter are: some little known but basic facts about the planetary motions; the conceptual framework and most important discoveries of Ptolemy and Copernicus; the complete change of concepts that Kepler introduced and their role in his discoveries; the significance of them in Newton's work; Mach's realization that Kepler's conceptual revolution needed further development to free Newton's conceptual world of the last vestiges of the purely geometrical Ptolemaic world view; and the precise formulation of Mach's principle required to place GR correctly in the line of conceptual and technical evolution that began with the ancient Greek astronomers.

  12. 5 CFR 551.401 - Basic principles.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Basic principles. 551.401 Section 551.401 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY ADMINISTRATION UNDER THE FAIR LABOR STANDARDS ACT Hours of Work General Provisions § 551.401 Basic principles. (a) All...

  13. 5 CFR 551.401 - Basic principles.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Basic principles. 551.401 Section 551.401 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY ADMINISTRATION UNDER THE FAIR LABOR STANDARDS ACT Hours of Work General Provisions § 551.401 Basic principles. (a) All...

  14. 43 CFR 2091.07 - Principles.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Principles. 2091.07 Section 2091.07 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT... Lands § 2091.07 Principles. (a) Generally, segregated lands are not available for application,...

  15. 43 CFR 2091.07 - Principles.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Principles. 2091.07 Section 2091.07 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT... Lands § 2091.07 Principles. (a) Generally, segregated lands are not available for application,...

  16. 43 CFR 2091.07 - Principles.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Principles. 2091.07 Section 2091.07 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT... Lands § 2091.07 Principles. (a) Generally, segregated lands are not available for application,...

  17. 43 CFR 2091.07 - Principles.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Principles. 2091.07 Section 2091.07 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT... Lands § 2091.07 Principles. (a) Generally, segregated lands are not available for application,...

  18. Hooke's Law: Applications of a Recurring Principle

    ERIC Educational Resources Information Center

    Giuliodori, Mauricio J.; Lujan, Heidi L.; Briggs, Whitney S.; Palani, Gurunanthan; DiCarlo, Stephen E.

    2009-01-01

    Students generally approach topics in physiology as a series of unrelated phenomena that share few underlying principles. However, if students recognized that the same underlying principles can be used to explain many physiological phenomena, they may gain a more unified understanding of physiological systems. To address this concern, we…

  19. Accounting Principles 30G. Interim Guide.

    ERIC Educational Resources Information Center

    Manitoba Dept. of Education and Training, Winnipeg.

    This curriculum guide was developed for a senior-level introductory accounting course for students in high schools in Manitoba. The course introduces Canadian accounting principles and practices; it applies Generally Accepted Accounting Principles (GAAP) to introductory financial accounting. The guide includes the following components: (1) an…

  20. 43 CFR 1601.0-8 - Principles.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Principles. 1601.0-8 Section 1601.0-8 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR GENERAL MANAGEMENT (1000) PLANNING, PROGRAMMING, BUDGETING Planning § 1601.0-8 Principles. The development,...

  1. Bilingual Evidence against the Principle of Contrast.

    ERIC Educational Resources Information Center

    Quay, Suzanne

    Prior research on early lexical acquisition in bilingual infants has been used by Clark (1987) to support the Principle of Contrast, which states that every two forms contrast in meaning. In this study of an English-Spanish bilingual child, it is argued that the Principle of Contrast is not applicable to bilingual acquisition in general. Daily…

  2. Quantum measurements and Landauer's principle

    NASA Astrophysics Data System (ADS)

    Shevchenko, V.

    2015-05-01

    Information processing systems must obey laws of physics. One of particular examples of this general statement is known as Landauer's principle - irreversible operations (such as erasure) performed by any computing device at finite temperature have to dissipate some amount of heat bound from below. Together with other results of this kind, Landauer's principle represents a fundamental limit any modern or future computer must obey. We discuss interpretation of the physics behind the Landauer's principle using a model of Unruh-DeWitt detector. Of particular interest is the validity of this limit in quantum domain. We systematically study finite time effects. It is shown, in particular, that in high temperature limit finiteness of measurement time leads to renormalization of the detector's temperature.

  3. DESIGN PRINCIPLES FOR WETLAND TREATMENT SYSTEMS

    EPA Science Inventory

    Published data pertaining to the treatment of wastewater by 26 wetlands have been assembled and analyzed to identify general principles for successful design of wetland facilities. Source of operating data have been tabulated. Performance is correlated with overall system feature...

  4. Principles of optical-data processing techniques

    NASA Technical Reports Server (NTRS)

    Shulman, A. R.

    1968-01-01

    Document presents optical-data processing information on a level which will convey the basic principles involved to those having a general technical background. Mathematical discussions are included but are not required for a basic understanding.

  5. How Many Principles for Public Health Ethics?

    PubMed Central

    Coughlin, Steven S.

    2009-01-01

    General moral (ethical) principles play a prominent role in certain methods of moral reasoning and ethical decision-making in bioethics and public health. Examples include the principles of respect for autonomy, beneficence, nonmaleficence, and justice. Some accounts of ethics in public health have pointed to additional principles related to social and environmental concerns, such as the precautionary principle and principles of solidarity or social cohesion. This article provides an overview of principle-based methods of moral reasoning as they apply to public health ethics including a summary of advantages and disadvantages of methods of moral reasoning that rely upon general principles of moral reasoning. Drawing upon the literature on public health ethics, examples are provided of additional principles, obligations, and rules that may be useful for analyzing complex ethical issues in public health. A framework is outlined that takes into consideration the interplay of ethical principles and rules at individual, community, national, and global levels. Concepts such as the precautionary principle and solidarity are shown to be useful to public health ethics to the extent that they can be shown to provide worthwhile guidance and information above and beyond principles of beneficence, nonmaleficence, and justice, and the clusters of rules and maxims that are linked to these moral principles. Future directions likely to be productive include further work on areas of public health ethics such as public trust, community empowerment, the rights of individuals who are targeted (or not targeted) by public health interventions, individual and community resilience and wellbeing, and further clarification of principles, obligations, and rules in public health disciplines such as environmental science, prevention and control of chronic and infectious diseases, genomics, and global health. PMID:20072707

  6. Chemical Principls Exemplified

    ERIC Educational Resources Information Center

    Plumb, Robert C.

    1973-01-01

    Two topics are discussed: (1) Stomach Upset Caused by Aspirin, illustrating principles of acid-base equilibrium and solubility; (2) Physical Chemistry of the Drinking Duck, illustrating principles of phase equilibria and thermodynamics. (DF)

  7. Principles of project management

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The basic principles of project management as practiced by NASA management personnel are presented. These principles are given as ground rules and guidelines to be used in the performance of research, development, construction or operational assignments.

  8. Magnetism: Principles and Applications

    NASA Astrophysics Data System (ADS)

    Craik, Derek J.

    2003-09-01

    If you are studying physics, chemistry, materials science, electrical engineering, information technology or medicine, then you'll know that understanding magnetism is fundamental to success in your studies and here is the key to unlocking the mysteries of magnetism....... You can: obtain a simple overview of magnetism, including the roles of B and H, resonances and special techniques take full advantage of modern magnets with a wealth of expressions for fields and forces develop realistic general design programmes using isoparametric finite elements study the subtleties of the general theory of magnetic moments and their dynamics follow the development of outstanding materials appreciate how magnetism encompasses topics as diverse as rock magnetism, chemical reaction rates, biological compasses, medical therapies, superconductivity and levitation understand the basis and remarkable achievements of magnetic resonance imaging In his new book, Magnetism, Derek Craik throws light on the principles and applications of this fascinating subject. From formulae for calculating fields to quantum theory, the secrets of magnetism are exposed, ensuring that whether you are a chemist or engineer, physicist, medic or materials scientist Magnetism is the book for our course.

  9. Principles of Modern Soccer.

    ERIC Educational Resources Information Center

    Beim, George

    This book is written to give a better understanding of the principles of modern soccer to coaches and players. In nine chapters the following elements of the game are covered: (1) the development of systems; (2) the principles of attack; (3) the principles of defense; (4) training games; (5) strategies employed in restarts; (6) physical fitness…

  10. Chemical Principles Exemplified

    ERIC Educational Resources Information Center

    Plumb, Robert C.

    1970-01-01

    This is the first of a new series of brief ancedotes about materials and phenomena which exemplify chemical principles. Examples include (1) the sea-lab experiment illustrating principles of the kinetic theory of gases, (2) snow-making machines illustrating principles of thermodynamics in gas expansions and phase changes, and (3) sunglasses that…

  11. Energy principles in architectural design

    SciTech Connect

    Dean, E.

    1981-01-01

    A foundation of basic information pertaining to design and energy use in buildings is presented with emphasis on principles and concepts rather than applications of particular solution. Energy impacts of landforms and topography, vegetation, wind and ventilation, and sun on planning and designing the site are discused. General design considerations involving passive heating, cooling, and lighting systems are detailed. For the design of active building systems, heating, cooling, lighting, and HVAC systems are described. (MCW)

  12. Driving Toward Guiding Principles

    PubMed Central

    Buckovich, Suzy A.; Rippen, Helga E.; Rozen, Michael J.

    1999-01-01

    As health care moves from paper to electronic data collection, providing easier access and dissemination of health information, the development of guiding privacy, confidentiality, and security principles is necessary to help balance the protection of patients' privacy interests against appropriate information access. A comparative review and analysis was done, based on a compilation of privacy, confidentiality, and security principles from many sources. Principles derived from ten identified sources were compared with each of the compiled principles to assess support level, uniformity, and inconsistencies. Of 28 compiled principles, 23 were supported by at least 50 percent of the sources. Technology could address at least 12 of the principles. Notable consistencies among the principles could provide a basis for consensus for further legislative and organizational work. It is imperative that all participants in our health care system work actively toward a viable resolution of this information privacy debate. PMID:10094065

  13. 48 CFR 31.204 - Application of principles and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... REGULATION GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Commercial... certain items for emphasis or clarity. (b)(1) For the following subcontract types, costs incurred...

  14. Radiation protection principles of NCRP.

    PubMed

    Kase, Kenneth R

    2004-09-01

    The current recommendations of the National Council on Radiation Protection and Measurements (NCRP) relative to ionizing radiation are based on radiation protection principles that developed historically as information about radiation effects on human populations became available. Because the NCRP Charter states that the NCRP will cooperate with the International Commission on Radiological Protection (ICRP), the basic principles and recommendations for radiation protection of the NCRP are closely coupled with those of the ICRP. Thus, the fundamental principles of justification, optimization, and dose limitation as initially stated in ICRP Publication 26 have been adopted and applied by the NCRP in its recommendations. ICRP and NCRP recommendations on dose limitation for the general public and for occupationally exposed individuals are based on the same analyses of radiation risk, and, while similar, there are differences reflecting the aspects of radiation application and exposure circumstances unique to the United States. The NCRP has recently extended its guidance to address exposure to individuals engaged in space activities. Several reports have been issued or are in preparation to provide recommendations on dose limitation and the development of radiation safety programs to apply the radiation protection principles in space activities. The biological basis for these recommendations is provided in these and accompanying NCRP reports. Recommendations for the application of basic radiation protection principles have been made in many reports over the years. Those that are most current appear in approximately 50 reports published in the last 15 y. These address radiation safety practices in industrial and medical institutions, control of radionuclides in the environment, protection of the public, and assessment of radiation risk. Some of the aspects of these recommendations will be discussed. Current recommendations related to radiation safety practice are based

  15. The precautionary principle: is it safe.

    PubMed

    Gignon, Maxime; Ganry, Olivier; Jardé, Olivier; Manaouil, Cécile

    2013-06-01

    The precautionary principle is generally acknowledged to be a powerful tool for protecting health but it was originally invoked by policy makers for dealing with environmental issues. In the 1990s, the principle was incorporated into many legislative and regulatory texts in international law. One can consider that the precautionary principle has turned into "precautionism" necessary to prove to the people, taking account of risk in decisions. There is now a risk that these abuses will deprive the principle of its meaning and value. When pushed to its limits, the precautionary principle can even be dangerous when applied to the healthcare field. This is why a critical analysis of the principle is necessary. Through the literature, it sometimes seems to deviate somehow from the essence of the precautionary principle as it is commonly used in relation to health. We believe that educational work is necessary to familiarize professionals, policy makers and public opinion of the precautionary principle and avoid confusion. We propose a critical analysis of the use and misuse of the precautionary principle. PMID:23984492

  16. 4 CFR 2.4 - Merit system principles.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 4 Accounts 1 2014-01-01 2013-01-01 true Merit system principles. 2.4 Section 2.4 Accounts GOVERNMENT ACCOUNTABILITY OFFICE PERSONNEL SYSTEM PURPOSE AND GENERAL PROVISION § 2.4 Merit system principles. (a) Merit personnel systems are based on the principle that an organization is best served by motivated, competent, honest and productive...

  17. Complementary Huygens Principle for Geometrical and Nongeometrical Optics

    ERIC Educational Resources Information Center

    Luis, Alfredo

    2007-01-01

    We develop a fundamental principle depicting the generalized ray formulation of optics provided by the Wigner function. This principle is formally identical to the Huygens-Fresnel principle but in terms of opposite concepts, rays instead of waves, and incoherent superpositions instead of coherent ones. This ray picture naturally includes…

  18. On Hamiltonian and Action Principle Formulations of Plasma Dynamics

    SciTech Connect

    Morrison, P. J.

    2009-11-10

    A general discussion of Hamiltonian and action principle formulations for fluid and plasma models is given. A procedure, based on Hamilton's principle of mechanics but adapted for continua, for the construction of action principles for fluid and kinetic models is given. The transformation from action principles in terms of the Lagrangian variable description to the Eulerian variable description in terms of noncanonical Poisson brackets is described. Two examples are developed: ideal MHD and Braginskii's fluid model with gyroviscosity.

  19. Mechanics, cosmology and Mach's principle

    NASA Astrophysics Data System (ADS)

    Essén, Hanno

    2013-01-01

    It is pointed out that recent cosmological findings seem to support the view that the mass/energy distribution of the universe defines the Newtonian inertial frames, as originally suggested by Mach. The background concepts of inertial frame, Newton's second law and fictitious forces are clarified. A precise definition of Mach's principle is suggested. Then, an approximation to general relativity discovered by Einstein, Infeld and Hoffmann is used and it is found that this precise formulation of Mach's principle is realized provided the mass/energy density of the universe has a specific value. This value turns out to be twice the critical density. The implications of this approximate result are put into context.

  20. Assessment Principles and Tools

    PubMed Central

    Golnik, Karl C.

    2014-01-01

    The goal of ophthalmology residency training is to produce competent ophthalmologists. Competence can only be determined by appropriately assessing resident performance. There are accepted guiding principles that should be applied to competence assessment methods. These principles are enumerated herein and ophthalmology-specific assessment tools that are available are described. PMID:24791100

  1. Principled Grammar Teaching

    ERIC Educational Resources Information Center

    Batstone, Rob; Ellis, Rod

    2009-01-01

    A key aspect of the acquisition of grammar for second language learners involves learning how to make appropriate connections between grammatical forms and the meanings which they typically signal. We argue that learning form/function mappings involves three interrelated principles. The first is the Given-to-New Principle, where existing world…

  2. Hamilton's Principle for Beginners

    ERIC Educational Resources Information Center

    Brun, J. L.

    2007-01-01

    I find that students have difficulty with Hamilton's principle, at least the first time they come into contact with it, and therefore it is worth designing some examples to help students grasp its complex meaning. This paper supplies the simplest example to consolidate the learning of the quoted principle: that of a free particle moving along a…

  3. The Principles of Leadership.

    ERIC Educational Resources Information Center

    Burns, Gerald P.

    The primary but not exclusive concern in this monograph is the principles and qualities of dynamic leaders of people rather than of ideas or cultural and artistic pursuits. Theories of leadership in the past, present, and future are discussed, as are the principles, rewards, exercise, and philosophy of leadership. A bibliography is included. (MSE)

  4. Government Information Policy Principles.

    ERIC Educational Resources Information Center

    Hernon, Peter

    1991-01-01

    Analyzes the utility of policy principles advanced by professional associations for public access to government information. The National Commission on Libraries and Information Science (NCLIS), the Information Industry Association (IIA), and the Office of Technology Assessment (OTA) urge the adoption of principles for the dissemination of public…

  5. Dynamic sealing principles

    NASA Technical Reports Server (NTRS)

    Zuk, J.

    1976-01-01

    The fundamental principles governing dynamic sealing operation are discussed. Different seals are described in terms of these principles. Despite the large variety of detailed construction, there appear to be some basic principles, or combinations of basic principles, by which all seals function, these are presented and discussed. Theoretical and practical considerations in the application of these principles are discussed. Advantages, disadvantages, limitations, and application examples of various conventional and special seals are presented. Fundamental equations governing liquid and gas flows in thin film seals, which enable leakage calculations to be made, are also presented. Concept of flow functions, application of Reynolds lubrication equation, and nonlubrication equation flow, friction and wear; and seal lubrication regimes are explained.

  6. Principlism and communitarianism.

    PubMed

    Callahan, D

    2003-10-01

    The decline in the interest in ethical theory is first outlined, as a background to the author's discussion of principlism. The author's own stance, that of a communitarian philosopher, is then described, before the subject of principlism itself is addressed. Two problems stand in the way of the author's embracing principlism: its individualistic bias and its capacity to block substantive ethical inquiry. The more serious problem the author finds to be its blocking function. Discussing the four scenarios the author finds that the utility of principlism is shown in the two scenarios about Jehovah's Witnesses but that when it comes to selling kidneys for transplantation and germline enhancement, principlism is of little help. PMID:14519838

  7. [The precautionary principle and the environment].

    PubMed

    de Cózar Escalante, José Manuel

    2005-01-01

    The precautionary principle is a response to uncertainty in the face of risks to health or the environment. In general, it involves taking measures to avoid potential harm, despite lack of scientific certainty. In recent years it has been applied, not without difficulties, as a legal and political principle in many countries, particularly on the European and International level. In spite of the controversy, the precautionary principle has become an integral component of a new paradigm for the creation of public policies needed to meet today's challenges and those of the future. PMID:15913050

  8. A New Principle in Physiscs: the Principle "Finiteness", and Some Consequences

    SciTech Connect

    Abraham Sternlieb

    2010-06-25

    In this paper I propose a new principle in physics: the principle of "finiteness". It stems from the definition of physics as a science that deals (among other things) with measurable dimensional physical quantities. Since measurement results, including their errors, are always finite, the principle of finiteness postulates that the mathematical formulation of "legitimate" laws of physics should prevent exactly zero or infinite solutions. Some consequences of the principle of finiteness are discussed, in general, and then more specifically in the fields of special relativity, quantum mechanics, and quantum gravity. The consequences are derived independently of any other theory or principle in physics. I propose "finiteness" as a postulate (like the constancy of the speed of light in vacuum, "c"), as opposed to a notion whose validity has to be corroborated by, or derived theoretically or experimentally from other facts, theories, or principles.

  9. Triangulating Speech Sound Generalization

    ERIC Educational Resources Information Center

    Miccio, Adele W.; Powell, Thomas W.

    2010-01-01

    Generalization refers to the extension of learned behaviours to novel conditions, and it is one of the criteria by which the effectiveness and efficiency of a remediation programme may be judged. This article extracts principles of generalization from the treatment literature, and provides examples of how this information may be used to help guide…

  10. Communication: General Semantics Perspectives.

    ERIC Educational Resources Information Center

    Thayer, Lee, Ed.

    This book contains the edited papers from the eleventh International Conference on General Semantics, titled "A Search for Relevance." The conference questioned, as a central theme, the relevance of general semantics in a world of wars and human misery. Reacting to a fundamental Korzybski-ian principle that man's view of reality is distorted by…

  11. Probing Students' Ideas of the Principle of Equivalence

    ERIC Educational Resources Information Center

    Bandyopadhyay, Atanu; Kumar, Arvind

    2011-01-01

    The principle of equivalence was the first vital clue to Einstein in his extension of special relativity to general relativity, the modern theory of gravitation. In this paper we investigate in some detail students' understanding of this principle in a variety of contexts, when they are undergoing an introductory course on general relativity. The…

  12. Compound Verbs in Persian: An Euphemistic Phraseology.

    ERIC Educational Resources Information Center

    Salies, Tania Gastao

    An analysis of the compound verb system of Persian marks constructions euphemistically by producing an indirect order effect and by alternating different compound and simple forms that bear the same denotation but are governed by a rigorous code of ethics. What really carries the semantic reference in these cases is the process of construing…

  13. Archimedes' Principle in Action

    ERIC Educational Resources Information Center

    Kires, Marian

    2007-01-01

    The conceptual understanding of Archimedes' principle can be verified in experimental procedures which determine mass and density using a floating object. This is demonstrated by simple experiments using graduated beakers. (Contains 5 figures.)

  14. Chemical Principles Exemplified

    ERIC Educational Resources Information Center

    Plumb, Robert C.

    1972-01-01

    Collection of two short descriptions of chemical principles seen in life situations: the autocatalytic reaction seen in the bombardier beetle, and molecular potential energy used for quick roasting of beef. Brief reference is also made to methanol lighters. (PS)

  15. Global ethics and principlism.

    PubMed

    Gordon, John-Stewart

    2011-09-01

    This article examines the special relation between common morality and particular moralities in the four-principles approach and its use for global ethics. It is argued that the special dialectical relation between common morality and particular moralities is the key to bridging the gap between ethical universalism and relativism. The four-principles approach is a good model for a global bioethics by virtue of its ability to mediate successfully between universal demands and cultural diversity. The principle of autonomy (i.e., the idea of individual informed consent), however, does need to be revised so as to make it compatible with alternatives such as family- or community-informed consent. The upshot is that the contribution of the four-principles approach to global ethics lies in the so-called dialectical process and its power to deal with cross-cultural issues against the background of universal demands by joining them together. PMID:22073817

  16. Triangulating speech sound generalization.

    PubMed

    Miccio, Adele W; Powell, Thomas W

    2010-01-01

    Generalization refers to the extension of learned behaviours to novel conditions, and it is one of the criteria by which the effectiveness and efficiency of a remediation programme may be judged. This article extracts principles of generalization from the treatment literature, and provides examples of how this information may be used to help guide treatment decisions. Included is a discussion of client, clinician, and treatment variables that may contribute to the generalization process. PMID:20345260

  17. The principle of conformational signaling.

    PubMed

    Tompa, Peter

    2016-07-25

    Signal transduction is the primary process by which cells respond to changes in their physical and chemical environments. Cellular response is initiated through a signaling protein (a receptor), which interacts with the "signal", most often a novel molecule outside or inside the cell. The mechanism of activation of the receptor is a conformational change and/or covalent modification, which then sets in motion a signaling pathway, i.e. a cascade of modification and binding events that relay and amplify the message to eventually alter the state of the cell. In reflection of this general perception, concepts such as the "second messenger" and the "phosphorylation cascade" dominate our views of signal transduction. The idea I advocate here is that the non-covalent change in protein conformation itself might serve as the initial or intermittent "signal" in the cascade, and it is often the primary event being recognized and interpreted by downstream receptor(s). This signaling principle is intertwined with many other cellular regulatory concepts, such as (pathway) allostery, conformational spread, induced folding/unfolding, conformational memory, the hierarchical assembly of complexes, and the action of regulatory chaperones and prions. By elaborating on many examples and also recent advances in experimental methodology, I show that conformational signaling, although thus far underappreciated, is a general and robust signaling principle that most of the time operates in close interplay with covalent signals in the cell. PMID:27242242

  18. The traveltime holographic principle

    NASA Astrophysics Data System (ADS)

    Huang, Yunsong; Schuster, Gerard T.

    2015-01-01

    Fermat's interferometric principle is used to compute interior transmission traveltimes τpq from exterior transmission traveltimes τsp and τsq. Here, the exterior traveltimes are computed for sources s on a boundary B that encloses a volume V of interior points p and q. Once the exterior traveltimes are computed, no further ray tracing is needed to calculate the interior times τpq. Therefore this interferometric approach can be more efficient than explicitly computing interior traveltimes τpq by ray tracing. Moreover, the memory requirement of the traveltimes is reduced by one dimension, because the boundary B is of one fewer dimension than the volume V. An application of this approach is demonstrated with interbed multiple (IM) elimination. Here, the IMs in the observed data are predicted from the migration image and are subsequently removed by adaptive subtraction. This prediction is enabled by the knowledge of interior transmission traveltimes τpq computed according to Fermat's interferometric principle. We denote this principle as the `traveltime holographic principle', by analogy with the holographic principle in cosmology where information in a volume is encoded on the region's boundary.

  19. Applying the four principles.

    PubMed

    Macklin, R

    2003-10-01

    Gillon is correct that the four principles provide a sound and useful way of analysing moral dilemmas. As he observes, the approach using these principles does not provide a unique solution to dilemmas. This can be illustrated by alternatives to Gillon's own analysis of the four case scenarios. In the first scenario, a different set of factual assumptions could yield a different conclusion about what is required by the principle of beneficence. In the second scenario, although Gillon's conclusion is correct, what is open to question is his claim that what society regards as the child's best interest determines what really is in the child's best interest. The third scenario shows how it may be reasonable for the principle of beneficence to take precedence over autonomy in certain circumstances, yet like the first scenario, the ethical conclusion relies on a set of empirical assumptions and predictions of what is likely to occur. The fourth scenario illustrates how one can draw different conclusions based on the importance given to the precautionary principle. PMID:14519836

  20. Dilaton cosmology and the modified uncertainty principle

    NASA Astrophysics Data System (ADS)

    Majumder, Barun

    2011-09-01

    Very recently Ali et al. (2009) proposed a new generalized uncertainty principle (with a linear term in Plank length which is consistent with doubly special relativity and string theory. The classical and quantum effects of this generalized uncertainty principle (termed as modified uncertainty principle or MUP) are investigated on the phase space of a dilatonic cosmological model with an exponential dilaton potential in a flat Friedmann-Robertson-Walker background. Interestingly, as a consequence of MUP, we found that it is possible to get a late time acceleration for this model. For the quantum mechanical description in both commutative and MUP framework, we found the analytical solutions of the Wheeler-DeWitt equation for the early universe and compare our results. We have used an approximation method in the case of MUP.

  1. Spaceborne receivers: Basic principles

    NASA Technical Reports Server (NTRS)

    Stacey, J. M.

    1984-01-01

    The underlying principles of operation of microwave receivers for space observations of planetary surfaces were examined. The design philosophy of the receiver as it is applied to operate functionally as an efficient receiving system, the principle of operation of the key components of the receiver, and the important differences among receiver types are explained. The operating performance and the sensitivity expectations for both the modulated and total power receiver configurations are outlined. The expressions are derived from first principles and are developed through the important intermediate stages to form practicle and easily applied equations. The transfer of thermodynamic energy from point to point within the receiver is illustrated. The language of microwave receivers is applied statistics.

  2. Teaching/learning principles

    NASA Technical Reports Server (NTRS)

    Hankins, D. B.; Wake, W. H.

    1981-01-01

    The potential remote sensing user community is enormous, and the teaching and training tasks are even larger; however, some underlying principles may be synthesized and applied at all levels from elementary school children to sophisticated and knowledgeable adults. The basic rules applying to each of the six major elements of any training course and the underlying principle involved in each rule are summarized. The six identified major elements are: (1) field sites for problems and practice; (2) lectures and inside study; (3) learning materials and resources (the kit); (4) the field experience; (5) laboratory sessions; and (6) testing and evaluation.

  3. 29 CFR 779.101 - Guiding principles for applying coverage and exemption provisions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Guiding principles for applying coverage and exemption provisions. 779.101 Section 779.101 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION... Apply: Basic Principles and Individual Coverage General Principles § 779.101 Guiding principles...

  4. 43 CFR 1601.0-8 - Principles.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Principles. 1601.0-8 Section 1601.0-8 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR GENERAL MANAGEMENT (1000) PLANNING, PROGRAMMING, BUDGETING Planning §...

  5. 43 CFR 1601.0-8 - Principles.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Principles. 1601.0-8 Section 1601.0-8 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR GENERAL MANAGEMENT (1000) PLANNING, PROGRAMMING, BUDGETING Planning §...

  6. 43 CFR 1601.0-8 - Principles.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Principles. 1601.0-8 Section 1601.0-8 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR GENERAL MANAGEMENT (1000) PLANNING, PROGRAMMING, BUDGETING Planning §...

  7. The Idiom Principle Revisited

    ERIC Educational Resources Information Center

    Siyanova-Chanturia, Anna; Martinez, Ron

    2015-01-01

    John Sinclair's Idiom Principle famously posited that most texts are largely composed of multi-word expressions that "constitute single choices" in the mental lexicon. At the time that assertion was made, little actual psycholinguistic evidence existed in support of that holistic, "single choice," view of formulaic language. In…

  8. Reprographic Principles Made Easy.

    ERIC Educational Resources Information Center

    Young, J. B.

    Means for reproducing graphic materials are explained. There are several types of processes: those using light sensitive material, those using heat sensitive material, those using photo conductive materials (electrophotography), and duplicating processes using ink. For each of these, the principles behind them are explained, the necessary…

  9. PRINCIPLES OF WATER FILTRATION

    EPA Science Inventory

    This paper reviews principles involved in the processes commonly used to filter drinking water for public water systems. he most common approach is to chemically pretreat water and filter it through a deep (2-1/2 to 3 ft) bed of granuu1ar media (coal or sand or combinations of th...

  10. Extended Mach Principle.

    ERIC Educational Resources Information Center

    Rosen, Joe

    1981-01-01

    Discusses the meaning of symmetry of the laws of physics and symmetry of the universe and the connection between symmetries and asymmetries of the laws of physics and those of the universe. An explanation of Hamilton's principle is offered. The material is suitable for informal discussions with students. (Author/SK)

  11. Basic Comfort Heating Principles.

    ERIC Educational Resources Information Center

    Dempster, Chalmer T.

    The material in this beginning book for vocational students presents fundamental principles needed to understand the heating aspect of the sheet metal trade and supplies practical experience to the student so that he may become familiar with the process of determining heat loss for average structures. Six areas covered are: (1) Background…

  12. Matters of Principle.

    ERIC Educational Resources Information Center

    Martz, Carlton

    1999-01-01

    This issue of "Bill of Rights in Action" looks at individuals who have stood on principle against authority or popular opinion. The first article investigates John Adams and his defense of British soldiers at the Boston Massacre trials. The second article explores Archbishop Thomas Becket's fatal conflict with England's King Henry II. The final…

  13. Principles of Biomedical Ethics

    PubMed Central

    Athar, Shahid

    2012-01-01

    In this presentation, I will discuss the principles of biomedical and Islamic medical ethics and an interfaith perspective on end-of-life issues. I will also discuss three cases to exemplify some of the conflicts in ethical decision-making. PMID:23610498

  14. Qualitative biomechanical principles for application in coaching.

    PubMed

    Knudson, Duane

    2007-01-01

    Many aspects of human movements in sport can be readily understood by Newtonian rigid-body mechanics. Many of these laws and biomechanical principles, however, are counterintuitive to a lot of people. There are also several problems in the application of biomechanics to sports, so the application of biomechanics in the qualitative analysis of sport skills by many coaches has been limited. Biomechanics scholars have long been interested in developing principles that facilitate the qualitative application of biomechanics to improve movement performance and reduce the risk of injury. This paper summarizes the major North American efforts to establish a set of general biomechanical principles of movement, and illustrates how principles can be used to improve the application of biomechanics in the qualitative analysis of sport technique. A coach helping a player with a tennis serve is presented as an example. The standardization of terminology for biomechanical principles is proposed as an important first step in improving the application ofbiomechanics in sport. There is also a need for international cooperation and research on the effectiveness of applying biomechanical principles in the coaching of sport techniques. PMID:17542182

  15. Le Chatelier's principle in replicator dynamics

    NASA Astrophysics Data System (ADS)

    Allahverdyan, Armen E.; Galstyan, Aram

    2011-10-01

    The Le Chatelier principle states that physical equilibria are not only stable, but they also resist external perturbations via short-time negative-feedback mechanisms: a perturbation induces processes tending to diminish its results. The principle has deep roots, e.g., in thermodynamics it is closely related to the second law and the positivity of the entropy production. Here we study the applicability of the Le Chatelier principle to evolutionary game theory, i.e., to perturbations of a Nash equilibrium within the replicator dynamics. We show that the principle can be reformulated as a majorization relation. This defines a stability notion that generalizes the concept of evolutionary stability. We determine criteria for a Nash equilibrium to satisfy the Le Chatelier principle and relate them to mutualistic interactions (game-theoretical anticoordination) showing in which sense mutualistic replicators can be more stable than (say) competing ones. There are globally stable Nash equilibria, where the Le Chatelier principle is violated even locally: in contrast to the thermodynamic equilibrium a Nash equilibrium can amplify small perturbations, though both types of equilibria satisfy the detailed balance condition.

  16. 48 CFR 31.302 - General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Educational Institutions 31.302 General. Office of Management and Budget (OMB) Circular No. A-21, Cost Principles for Educational Institutions, revised, provides principles for determining the costs applicable to research and development,...

  17. 48 CFR 31.302 - General.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Educational Institutions 31.302 General. Office of Management and Budget (OMB) Circular No. A-21, Cost Principles for Educational Institutions, revised, provides principles for determining the costs applicable to research and development,...

  18. 48 CFR 31.302 - General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Educational Institutions 31.302 General. Office of Management and Budget (OMB) Circular No. A-21, Cost Principles for Educational Institutions, revised, provides principles for determining the costs applicable to research and development,...

  19. 48 CFR 31.302 - General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Educational Institutions 31.302 General. Office of Management and Budget (OMB) Circular No. A-21, Cost Principles for Educational Institutions, revised, provides principles for determining the costs applicable to research and development,...

  20. 48 CFR 31.302 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Educational Institutions 31.302 General. Office of Management and Budget (OMB) Circular No. A-21, Cost Principles for Educational Institutions, revised, provides principles for determining the costs applicable to research and development,...

  1. The equivalence principle in a quantum world

    NASA Astrophysics Data System (ADS)

    Bjerrum-Bohr, N. E. J.; Donoghue, John F.; El-Menoufi, Basem Kamal; Holstein, Barry R.; Planté, Ludovic; Vanhove, Pierre

    2015-09-01

    We show how modern methods can be applied to quantum gravity at low energy. We test how quantum corrections challenge the classical framework behind the equivalence principle (EP), for instance through introduction of nonlocality from quantum physics, embodied in the uncertainty principle. When the energy is small, we now have the tools to address this conflict explicitly. Despite the violation of some classical concepts, the EP continues to provide the core of the quantum gravity framework through the symmetry — general coordinate invariance — that is used to organize the effective field theory (EFT).

  2. A geodesic principle for strong coupling gravity

    NASA Astrophysics Data System (ADS)

    Niedermaier, Max

    2015-11-01

    Strong coupling gravity arises from general relativity by a scaling limit that preserves the number of physical degrees of freedom as well as covariance under the group of spatio-temporal diffeomorphisms. An intrinsic geodesic principle for it is formulated and justified. Geodesic congruences and the test bodies following them are, according to the principle, unaffected by nonlinear gravitational waves and can be gauged-fixed so as to never depart from their initial values. Among other consequences this offers a new perspective on gravitational coarse graining.

  3. Derivation of GFDM Based on OFDM Principles

    SciTech Connect

    Hussein Moradi; Behrouz Farhang-Boroujeny

    2015-06-01

    This paper starts with discussing the principle based on which the celebrated orthogonal frequency division multiplexing (OFDM) signals are constructed. It then extends the same principle to construct the newly introduced generalized frequency division multiplexing (GFDM) signals. This novel derivation sheds light on some interesting properties of GFDM. In particular, our derivation seamlessly leads to an implementation of GFDM transmitter which has significantly lower complexity than what has been reported so far. Our derivation also facilitates a trivial understanding of how GFDM (similar to OFDM) can be applied in MIMO channels.

  4. First principles of Hamiltonian medicine

    PubMed Central

    Crespi, Bernard; Foster, Kevin; Úbeda, Francisco

    2014-01-01

    We introduce the field of Hamiltonian medicine, which centres on the roles of genetic relatedness in human health and disease. Hamiltonian medicine represents the application of basic social-evolution theory, for interactions involving kinship, to core issues in medicine such as pathogens, cancer, optimal growth and mental illness. It encompasses three domains, which involve conflict and cooperation between: (i) microbes or cancer cells, within humans, (ii) genes expressed in humans, (iii) human individuals. A set of six core principles, based on these domains and their interfaces, serves to conceptually organize the field, and contextualize illustrative examples. The primary usefulness of Hamiltonian medicine is that, like Darwinian medicine more generally, it provides novel insights into what data will be productive to collect, to address important clinical and public health problems. Our synthesis of this nascent field is intended predominantly for evolutionary and behavioural biologists who aspire to address questions directly relevant to human health and disease. PMID:24686937

  5. A Simple Model of Entrepreneurship for Principles of Economics Courses

    ERIC Educational Resources Information Center

    Gunter, Frank R.

    2012-01-01

    The critical roles of entrepreneurs in creating, operating, and destroying markets, as well as their importance in driving long-term economic growth are still generally either absent from principles of economics texts or relegated to later chapters. The primary difficulties in explaining entrepreneurship at the principles level are the lack of a…

  6. 17 CFR 38.100 - Core Principle 1.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... MARKETS Designation as Contract Market § 38.100 Core Principle 1. (a) In general. To be designated, and maintain a designation, as a contract market, a board of trade shall comply with: (1) Any core principle... regulation pursuant to section 8a(5) of the Act. (b) Reasonable discretion of the contract market....

  7. 17 CFR 38.100 - Core Principle 1.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... MARKETS Designation as Contract Market § 38.100 Core Principle 1. (a) In general. To be designated, and maintain a designation, as a contract market, a board of trade shall comply with: (1) Any core principle... regulation pursuant to section 8a(5) of the Act. (b) Reasonable discretion of the contract market....

  8. 36 CFR 905.735-101 - Principles and purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Principles and purpose. 905.735-101 Section 905.735-101 Parks, Forests, and Public Property PENNSYLVANIA AVENUE DEVELOPMENT CORPORATION STANDARDS OF CONDUCT General Provisions § 905.735-101 Principles and purpose. In order to assure that the business of the Pennsylvania...

  9. Ethical Principles of Psychologists and Code of Conduct.

    ERIC Educational Resources Information Center

    American Psychologist, 2002

    2002-01-01

    Describes the American Psychological Association's Ethical Principles of Psychologists and Code of Conduct, focusing on introduction and applicability; preamble; general principles; and ethical standards (resolving ethical issues, competence, human relations, privacy and confidentiality, advertising and other public statements, record keeping and…

  10. 32 CFR 11.4 - Applicable principles of law.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Accused's acts. As provided in 32 CFR 9.5(c), the prosecution bears the burden of establishing the Accused... 32 National Defense 1 2011-07-01 2011-07-01 false Applicable principles of law. 11.4 Section 11.4... ELEMENTS FOR TRIALS BY MILITARY COMMISSION § 11.4 Applicable principles of law. (a) General intent....

  11. GST Revisited: Working Systems Principles for Training and Development Consultants.

    ERIC Educational Resources Information Center

    Owens, Elizabeth

    1990-01-01

    Presents seven principles for applying technology to training and development problems. Based on General Systems Theory (GST), these principles were developed to help with long-term decisions. Highlights include instructional systems development models; complexity in cultural systems; matching training materials to user characteristics; systems…

  12. Principles and Practices for Championship Performances in Wheelchair Field Events.

    ERIC Educational Resources Information Center

    Practical Pointers, 1980

    1980-01-01

    The article discusses training and competing in wheelchair sports. General principles of training, including scheduling and content considerations, are listed. Principles for specific wheelchair events (shotput, discus, and javelin) are detailed. A final part addresses training for the wheelchair pentathlon, which includes archery, swimming,…

  13. A correspondence principle

    NASA Astrophysics Data System (ADS)

    Hughes, Barry D.; Ninham, Barry W.

    2016-02-01

    A single mathematical theme underpins disparate physical phenomena in classical, quantum and statistical mechanical contexts. This mathematical "correspondence principle", a kind of wave-particle duality with glorious realizations in classical and modern mathematical analysis, embodies fundamental geometrical and physical order, and yet in some sense sits on the edge of chaos. Illustrative cases discussed are drawn from classical and anomalous diffusion, quantum mechanics of single particles and ideal gases, quasicrystals and Casimir forces.

  14. Pauli Exclusion Principle

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    A principle of quantum theory, devised in 1925 by Wolfgang Pauli (1900-58), which states that no two fermions may exist in the same quantum state. The quantum state of a particle is defined by a set of numbers that describe quantities such as energy, angular momentum and spin. Fermions are particles such as quarks, protons, neutrons and electrons, that have spin = ½ (in units of h/2π, where h is ...

  15. Principles of nuclear geology

    SciTech Connect

    Aswathanarayana, U.

    1985-01-01

    This book treats the basic principles of nuclear physics and the mineralogy, geochemistry, distribution and ore deposits of uranium and thorium. The application of nuclear methodology in radiogenic heat and thermal regime of the earth, radiometric prospecting, isotopic age dating, stable isotopes and cosmic-ray produced isotopes is covered. Geological processes, such as metamorphic chronology, petrogenesis, groundwater movement, and sedimentation rate are focussed on.

  16. Heisenberg's observability principle

    NASA Astrophysics Data System (ADS)

    Wolff, Johanna

    2014-02-01

    Werner Heisenberg's 1925 paper 'Quantum-theoretical re-interpretation of kinematic and mechanical relations' marks the beginning of quantum mechanics. Heisenberg famously claims that the paper is based on the idea that the new quantum mechanics should be 'founded exclusively upon relationships between quantities which in principle are observable'. My paper is an attempt to understand this observability principle, and to see whether its employment is philosophically defensible. Against interpretations of 'observability' along empiricist or positivist lines I argue that such readings are philosophically unsatisfying. Moreover, a careful comparison of Heisenberg's reinterpretation of classical kinematics with Einstein's argument against absolute simultaneity reveals that the positivist reading does not fit with Heisenberg's strategy in the paper. Instead the appeal to observability should be understood as a specific criticism of the causal inefficacy of orbital electron motion in Bohr's atomic model. I conclude that the tacit philosophical principle behind Heisenberg's argument is not a positivistic connection between observability and meaning, but the idea that a theory should not contain causally idle wheels.

  17. Exclusivity principle and the quantum bound of the Bell inequality

    NASA Astrophysics Data System (ADS)

    Cabello, Adán

    2014-12-01

    We show that, for general probabilistic theories admitting sharp measurements, the exclusivity principle together with two assumptions exactly singles out the Tsirelson bound of the Clauser-Horne-Shimony-Holt Bell inequality.

  18. Principles of tendon transfers.

    PubMed

    Coulet, B

    2016-04-01

    Tendon transfers are carried out to restore functional deficits by rerouting the remaining intact muscles. Transfers are highly attractive in the context of hand surgery because of the possibility of restoring the patient's ability to grip. In palsy cases, tendon transfers are only used when a neurological procedure is contraindicated or has failed. The strategy used to restore function follows a common set of principles, no matter the nature of the deficit. The first step is to clearly distinguish between deficient muscles and muscles that could be transferred. Next, the type of palsy will dictate the scope of the program and the complexity of the gripping movements that can be restored. Based on this reasoning, a surgical strategy that matches the means (transferable muscles) with the objectives (functions to restore) will be established and clearly explained to the patient. Every paralyzed hand can be described using three parameters. 1) Deficient segments: wrist, thumb and long fingers; 2) mechanical performance of muscles groups being revived: high energy-wrist extension and finger flexion that require strong transfers with long excursion; low energy-wrist flexion and finger extension movements that are less demanding mechanically, because they can be accomplished through gravity alone in some cases; 3) condition of the two primary motors in the hand: extrinsics (flexors and extensors) and intrinsics (facilitator). No matter the type of palsy, the transfer surgery follows the same technical principles: exposure, release, fixation, tensioning and rehabilitation. By performing an in-depth analysis of each case and by following strict technical principles, tendon transfer surgery leads to reproducible results; this allows the surgeon to establish clear objectives for the patient preoperatively. PMID:27117119

  19. Protection - Principles and practice.

    NASA Technical Reports Server (NTRS)

    Graham, G. S.; Denning, P. J.

    1972-01-01

    The protection mechanisms of computer systems control the access to objects, especially information objects. The principles of protection system design are formalized as a model (theory) of protection. Each process has a unique identification number which is attached by the system to each access attempted by the process. Details of system implementation are discussed, taking into account the storing of the access matrix, aspects of efficiency, and the selection of subjects and objects. Two systems which have protection features incorporating all the elements of the model are described.

  20. The principle of reciprocity.

    PubMed

    Hoult, D I

    2011-12-01

    The circumstances surrounding the realisation that NMR signal reception could be quantified in a simple fundamental manner using Lorentz's Principle of Reciprocity are described. The poor signal-to-noise ratio of the first European superconducting magnet is identified as a major motivating factor, together with the author's need to understand phenomena at a basic level. A summary is then given of the thought processes leading to the very simple pseudo-static formula that has been the basis of signal-to-noise calculations for over a generation. PMID:21889377

  1. Talus fractures: surgical principles.

    PubMed

    Rush, Shannon M; Jennings, Meagan; Hamilton, Graham A

    2009-01-01

    Surgical treatment of talus fractures can challenge even the most skilled foot and ankle surgeon. Complicated fracture patterns combined with joint dislocation of variable degrees require accurate assessment, sound understanding of principles of fracture care, and broad command of internal fixation techniques needed for successful surgical care. Elimination of unnecessary soft tissue dissection, a low threshold for surgical reduction, liberal use of malleolar osteotomy to expose body fracture, and detailed attention to fracture reduction and joint alignment are critical to the success of treatment. Even with the best surgical care complications are common and seem to correlate with injury severity and open injuries. PMID:19121756

  2. Nonequilibrium quantum Landauer principle.

    PubMed

    Goold, John; Paternostro, Mauro; Modi, Kavan

    2015-02-13

    Using the operational framework of completely positive, trace preserving operations and thermodynamic fluctuation relations, we derive a lower bound for the heat exchange in a Landauer erasure process on a quantum system. Our bound comes from a nonphenomenological derivation of the Landauer principle which holds for generic nonequilibrium dynamics. Furthermore, the bound depends on the nonunitality of dynamics, giving it a physical significance that differs from other derivations. We apply our framework to the model of a spin-1/2 system coupled to an interacting spin chain at finite temperature. PMID:25723198

  3. Principles of smile design

    PubMed Central

    Bhuvaneswaran, Mohan

    2010-01-01

    An organized and systematic approach is required to evaluate, diagnose and resolve esthetic problems predictably. It is of prime importance that the final result is not dependent only on the looks alone. Our ultimate goal as clinicians is to achieve pleasing composition in the smile by creating an arrangement of various esthetic elements. This article reviews the various principles that govern the art of smile designing. The literature search was done using PubMed search and Medline. This article will provide a basic knowledge to the reader to bring out a functional stable smile. PMID:21217950

  4. Academic Principles: A Brief Introduction

    ERIC Educational Resources Information Center

    Association of American Universities, 2013

    2013-01-01

    For many decades certain core principles have guided the conduct of teaching, research, and scholarship at American universities, as well as the ways in which these institutions are governed. There is ample evidence that these principles have strongly contributed to the quality of American universities. The principles have also made these…

  5. Principles of climate service development

    NASA Astrophysics Data System (ADS)

    Buontempo, Carlo; Liggins, Felicity; Newton, Paula

    2015-04-01

    In November 2014, a group of 30 international experts in climate service development gathered in Honiton, UK, to discuss and identify the key principles that should be considered when developing new climate services by all the actors involved. Through an interactive and dynamic workshop the attendees identified seven principles. This contribution summarises these principles.

  6. Probing students' ideas of the principle of equivalence

    NASA Astrophysics Data System (ADS)

    Bandyopadhyay, Atanu; Kumar, Arvind

    2011-01-01

    The principle of equivalence was the first vital clue to Einstein in his extension of special relativity to general relativity, the modern theory of gravitation. In this paper we investigate in some detail students' understanding of this principle in a variety of contexts, when they are undergoing an introductory course on general relativity. The tool of assessment is a diagnostic questionnaire administered to a group of 30 senior undergraduates going through the course. The analysis of responses reveals a number of significant conceptual vulnerabilities in several aspects of the topic. The most important among these is related to the notion of an inertial frame that follows naturally from the principle of equivalence.

  7. Microscopic black hole stabilization via the uncertainty principle

    NASA Astrophysics Data System (ADS)

    Vayenas, Constantinos G.; Grigoriou, Dimitrios

    2015-01-01

    Due to the Heisenberg uncertainty principle, gravitational confinement of two- or three-rotating particle systems can lead to microscopic Planckian or sub-Planckian black holes with a size of order their Compton wavelength. Some properties of such states are discussed in terms of the Schwarzschild geodesics of general relativity and compared with properties computed via the combination of special relativity, equivalence principle, Newton's gravitational law and Compton wavelength. It is shown that the generalized uncertainty principle (GUP) provides a satisfactory fit of the Schwarzschild radius and Compton wavelength of such microscopic, particle-like, black holes.

  8. Principles of Safety Pharmacology

    PubMed Central

    Pugsley, M K; Authier, S; Curtis, M J

    2008-01-01

    Safety Pharmacology is a rapidly developing discipline that uses the basic principles of pharmacology in a regulatory-driven process to generate data to inform risk/benefit assessment. The aim of Safety Pharmacology is to characterize the pharmacodynamic/pharmacokinetic (PK/PD) relationship of a drug's adverse effects using continuously evolving methodology. Unlike toxicology, Safety Pharmacology includes within its remit a regulatory requirement to predict the risk of rare lethal events. This gives Safety Pharmacology its unique character. The key issues for Safety Pharmacology are detection of an adverse effect liability, projection of the data into safety margin calculation and finally clinical safety monitoring. This article sets out to explain the drivers for Safety Pharmacology so that the wider pharmacology community is better placed to understand the discipline. It concludes with a summary of principles that may help inform future resolution of unmet needs (especially establishing model validation for accurate risk assessment). Subsequent articles in this issue of the journal address specific aspects of Safety Pharmacology to explore the issues of model choice, the burden of proof and to highlight areas of intensive activity (such as testing for drug-induced rare event liability, and the challenge of testing the safety of so-called biologics (antibodies, gene therapy and so on.). PMID:18604233

  9. Principles of immunology.

    PubMed

    Lentz, Ashley K; Feezor, Robert J

    2003-12-01

    The immune system, composed of innate and acquired immunity, allows an organism to fight off foreign pathogens. Healthy immunity accomplishes four essential principles: (1) ability to detect and fight off infection; (2) ability to recognize a host's own cells as "self," thereby protecting them from attack; (3) a memory from previous foreign infections; and (4) ability to limit the response after the pathogen has been removed. In an unaltered state, the intricate network of immunologic organs and cells creates an environment for proper host defense. Without adequate execution of immunologic mechanisms, a host is rendered defenseless against pathogens. Conversely, an unchecked immune response can be self-destructive. As a result of either of these untoward sequelae, immune dysfunction can elicit disease states in the host. The goal of this review is to elucidate the characteristics of a healthy immune system, focusing on the principles of immunity and the cells that participate in host protection. We also briefly discuss the clinical ramifications of immune dysfunction. PMID:16215081

  10. Revisiting Tversky's diagnosticity principle.

    PubMed

    Evers, Ellen R K; Lakens, Daniël

    2014-01-01

    Similarity is a fundamental concept in cognition. In 1977, Amos Tversky published a highly influential feature-based model of how people judge the similarity between objects. The model highlights the context-dependence of similarity judgments, and challenged geometric models of similarity. One of the context-dependent effects Tversky describes is the diagnosticity principle. The diagnosticity principle determines which features are used to cluster multiple objects into subgroups. Perceived similarity between items within clusters is expected to increase, while similarity between items in different clusters decreases. Here, we present two pre-registered replications of the studies on the diagnosticity effect reported in Tversky (1977). Additionally, one alternative mechanism that has been proposed to play a role in the original studies, an increase in the choice for distractor items (a substitution effect, see Medin et al., 1995), is examined. Our results replicate those found by Tversky (1977), revealing an average diagnosticity-effect of 4.75%. However, when we eliminate the possibility of substitution effects confounding the results, a meta-analysis of the data provides no indication of any remaining effect of diagnosticity. PMID:25161638

  11. Revisiting Tversky's diagnosticity principle

    PubMed Central

    Evers, Ellen R. K.; Lakens, Daniël

    2013-01-01

    Similarity is a fundamental concept in cognition. In 1977, Amos Tversky published a highly influential feature-based model of how people judge the similarity between objects. The model highlights the context-dependence of similarity judgments, and challenged geometric models of similarity. One of the context-dependent effects Tversky describes is the diagnosticity principle. The diagnosticity principle determines which features are used to cluster multiple objects into subgroups. Perceived similarity between items within clusters is expected to increase, while similarity between items in different clusters decreases. Here, we present two pre-registered replications of the studies on the diagnosticity effect reported in Tversky (1977). Additionally, one alternative mechanism that has been proposed to play a role in the original studies, an increase in the choice for distractor items (a substitution effect, see Medin et al., 1995), is examined. Our results replicate those found by Tversky (1977), revealing an average diagnosticity-effect of 4.75%. However, when we eliminate the possibility of substitution effects confounding the results, a meta-analysis of the data provides no indication of any remaining effect of diagnosticity. PMID:25161638

  12. Chemical Principles Revisited: Perspectives on the Uncertainty Principle and Quantum Reality.

    ERIC Educational Resources Information Center

    Bartell, Lawrence S.

    1985-01-01

    Explicates an approach that not only makes the uncertainty seem more useful to introductory students but also helps convey the real meaning of the term "uncertainty." General topic areas addressed include probability amplitudes, rationale behind the uncertainty principle, applications of uncertainty relations, and quantum processes. (JN)

  13. Principles of Invariance in Radiative Transfer

    NASA Astrophysics Data System (ADS)

    Peraiah, A.

    1999-09-01

    We have reviewed the principle of invariance, its applications and its usefulness for obtaining the radiation field in semi-infinite and finite atmospheres. Various laws of scattering in dispersive media and the consequent radiation field are studied. The H-functions and X- and Y-functions in semi-infinite and finite media respectively are derived in a few cases. The Discrete Space Theory (DST) which is a general form of the Principle of Invariance is described. The method of addition of layers with general properties, is shown to describe all the properties of multiple scattering. A few examples of the application of DST such as polarization, line formation in expanding stellar atmospheres, etc., and a numerical analysis of DST are presented. Other developments in the theory of radiative transfer are briefly described.

  14. An uncertainty principle for unimodular quantum groups

    SciTech Connect

    Crann, Jason; Kalantar, Mehrdad E-mail: mkalanta@math.carleton.ca

    2014-08-15

    We present a generalization of Hirschman's entropic uncertainty principle for locally compact Abelian groups to unimodular locally compact quantum groups. As a corollary, we strengthen a well-known uncertainty principle for compact groups, and generalize the relation to compact quantum groups of Kac type. We also establish the complementarity of finite-dimensional quantum group algebras. In the non-unimodular setting, we obtain an uncertainty relation for arbitrary locally compact groups using the relative entropy with respect to the Haar weight as the measure of uncertainty. We also show that when restricted to q-traces of discrete quantum groups, the relative entropy with respect to the Haar weight reduces to the canonical entropy of the random walk generated by the state.

  15. General principles of pharmaceutical solid polymorphism: a supramolecular perspective.

    PubMed

    Rodríguez-Spong, Barbara; Price, Christopher P; Jayasankar, Adivaraha; Matzger, Adam J; Rodríguez-Hornedo, Naír

    2004-02-23

    The diversity of solid-state forms that an active pharmaceutical ingredient (API) may attain relies on the repertoire of non-covalent interactions and molecular assemblies, the range of order, and the balance between entropy and enthalpy that defines the free energy landscape. It is recognized that crystallization is associated with molecular recognition events that lead to self-assembly, and that pharmaceutical function and thermodynamic stability can be altered with a slight change in the interacting molecules or their molecular network motifs. Our current understanding of pharmaceutical solids in terms of molecular recognition and complementarity provides new insights into the design and function of single and fully miscible, multiple-component solids with varying degrees of order, from amorphous to crystalline states, and in this way is leading the path to supramolecular pharmaceutics. This review describes pharmaceutical solids in terms of supramolecular chemistry and crystal engineering concepts, and discusses the events that control crystallization and solid phase transformations. PMID:14962581

  16. 2 CFR Appendix A to Part 230 - General Principles

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... income (i.e., gross income earned from federally-supported activities) see § 215.24 of 2 CFR part 215... but the allocability of costs provisions of Appendix A, subsection C.e. of 2 CFR part 225 (OMB Circular A-87); Appendix A, Section C.4. of 2 CFR part 220 (OMB Circular A-21); Section A.4. of...

  17. Symbiosis as a General Principle in Eukaryotic Evolution

    PubMed Central

    Douglas, Angela E.

    2014-01-01

    Eukaryotes have evolved and diversified in the context of persistent colonization by non-pathogenic microorganisms. Various resident microorganisms provide a metabolic capability absent from the host, resulting in increased ecological amplitude and often evolutionary diversification of the host. Some microorganisms confer primary metabolic pathways, such as photosynthesis and cellulose degradation, and others expand the repertoire of secondary metabolism, including the synthesis of toxins that confer protection against natural enemies. A further route by which microorganisms affect host fitness arises from their modulation of the eukaryotic-signaling networks that regulate growth, development, behavior, and other functions. These effects are not necessarily based on interactions beneficial to the host, but can be a consequence of either eukaryotic utilization of microbial products as cues or host–microbial conflict. By these routes, eukaryote–microbial interactions play an integral role in the function and evolutionary diversification of eukaryotes. PMID:24492707

  18. [General principles of wound management in emergency departments].

    PubMed

    Zacher, M T; Högele, A M; Hanschen, M; von Matthey, F; Beer, A-K; Gebhardt, F; Biberthaler, P; Kanz, K-G

    2016-04-01

    Wound management is one of the major tasks in emergency departments. The surrounding intact skin but not the wound itself should be disinfected before starting definitive wound treatment. Hair should first be removed by clipping to 1-2 mm above the skin with scissors or clippers as shaving the area with a razor damages the hair follicles and increases the risk of wound infections. Administration of local anesthetics should be performed directly through the exposed edges of the wound. After wound examination, irrigation is performed with Ringer's solution, normal saline or distilled water. The next step is débridement of contaminated and devitalized tissue. There are several wound closure techniques available, including adhesive tapes, staples, tissue adhesives and numerous forms of sutures. Management of specific wounds requires particular strategies. A bleeding control problem frequently occurs with scalp lacerations. Superficial scalp lacerations can be closed by alternative wound closure methods, for example by twisting and fixing hair and the use of tissue adhesives, i.e. hair apposition technique (HAT). For strongly bleeding lacerations of the scalp, the epicranial aponeurosis should be incorporated into the hemostasis. Aftercare varies depending on both the characteristics of the wound and those of the patient and includes adequate analgesia as well as minimizing the risk of infection. Sufficient wound aftercare starts with the treating physician informing the patient about the course of events, potential complications and providing relevant instructions. PMID:27059794

  19. 23 CFR 627.5 - General principles and procedures.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... studies. (2) Studies. Value engineering studies shall follow the widely recognized systematic problem-solving analysis process that is used throughout private industry and governmental agencies. Studies must... project meeting the project criteria in 23 CFR 627.1(a), the STDs shall fulfill the value...

  20. 10 CFR 1023.3 - Principles of general applicability.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... oral) regarding any matter at issue in an appeal, nor shall any member of the Board or of the Board's... not be subject to administrative appeal or administrative review. (b) Alternative Dispute Resolution... judges limited to the nature, procedures, and availability of ADR through the Board are permitted...

  1. 10 CFR 1023.3 - Principles of general applicability.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... oral) regarding any matter at issue in an appeal, nor shall any member of the Board or of the Board's... not be subject to administrative appeal or administrative review. (b) Alternative Dispute Resolution... judges limited to the nature, procedures, and availability of ADR through the Board are permitted...

  2. Operative technique of endoscopic thyroidectomy: a narration of general principles.

    PubMed

    Bhargav, P R K; Amar, V

    2013-06-01

    Endoscopic thyroidectomy is fast becoming a reality with increasing experience in endocrine surgery. Many techniques of minimally invasive video-assisted thyroidectomy through cervical and extra-cervical routes such as chest wall, transaxillary, trans-oral, post-auricular, trans-luminal approach have been attempted. At present anterior chest wall or trans-axillary routes are favourite extra-cervical routes. In this context, we describe our operative technique of endoscopic thyroidectomy through chest wall to highlight the surgical steps of practical importance. PMID:24426430

  3. Cancer and Aging: General Principles, Biology, and Geriatric Assessment.

    PubMed

    Li, Daneng; de Glas, Nienke A; Hurria, Arti

    2016-02-01

    Cancer is a disease of aging as older adults are much more likely to develop cancer compared with their younger counterparts. Understanding the biology of cancer and aging remains complex, and numerous theories regarding the relationship between the two have been proposed. Cancer treatment decisions in older patients are particularly challenging, because the evidence is scarce and the risk of toxicity increases with age. Determination of biologic age is essential due to heterogeneity of functional status, comorbidity, and physiologic reserves between patients of the same chronologic age. PMID:26614857

  4. General principles of single-construct chromosomal gene drive.

    PubMed

    Marshall, John M; Hay, Bruce A

    2012-07-01

    Gene drive systems are genetic elements capable of spreading into a population even if they confer a fitness cost to their host. We consider a class of drive systems consisting of a chromosomally located, linked cluster of genes, the presence of which renders specific classes of offspring arising from specific parental crosses unviable. Under permissive conditions, a number of these elements are capable of distorting the offspring ratio in their favor. We use a population genetic framework to derive conditions under which these elements spread to fixation in a population or induce a population crash. Many of these systems can be engineered using combinations of toxin and antidote genes, analogous to Medea, which consists of a maternal toxin and zygotic antidote. The majority of toxin-antidote drive systems require a critical frequency to be exceeded before they spread into a population. Of particular interest, a Z-linked Medea construct with a recessive antidote is expected to induce an all-male population crash for release frequencies above 50%. We suggest molecular tools that may be used to build these systems, and discuss their relevance to the control of a variety of insect pest species, including mosquito vectors of diseases such as malaria and dengue fever. PMID:22759292

  5. Chemical Principles Revisited: Updating the Atomic Theory in General Chemistry.

    ERIC Educational Resources Information Center

    Whitman, Mark

    1984-01-01

    Presents a descriptive overview of recent achievements in atomic structure to provide instructors with the background necessary to enhance their classroom presentations. Topics considered include hadrons, quarks, leptons, forces, and the unified fields theory. (JN)

  6. Calcium signalling and calcium channels: evolution and general principles.

    PubMed

    Verkhratsky, Alexei; Parpura, Vladimir

    2014-09-15

    Calcium as a divalent cation was selected early in evolution as a signaling molecule to be used by both prokaryotes and eukaryotes. Its low cytosolic concentration likely reflects the initial concentration of this ion in the primordial soup/ocean as unicellular organisms were formed. As the concentration of calcium in the ocean subsequently increased, so did the diversity of homeostatic molecules handling calcium. This includes the plasma membrane channels that allowed the calcium entry, as well as extrusion mechanisms, i.e., exchangers and pumps. Further diversification occurred with the evolution of intracellular organelles, in particular the endoplasmic reticulum and mitochondria, which also contain channels, exchanger(s) and pumps to handle the homeostasis of calcium ions. Calcium signalling system, based around coordinated interactions of the above molecular entities, can be activated by the opening of voltage-gated channels, neurotransmitters, second messengers and/or mechanical stimulation, and as such is all-pervading pathway in physiology and pathophysiology of organisms. PMID:24291103

  7. 9 CFR 381.413 - Nutrient content claims; general principles.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... formulas and medical foods, as described in 21 CFR 101.13(q)(4). (5) (6) Nutrient content claims that were...; (B) Fruits and vegetables; (C) Milk, yogurt, and cheese; (D) Meat, poultry, fish, dry beans, eggs...)(E) of this section. (A) Bread, cereal, rice, and pasta; (B) Fruits and vegetables; (C) Milk,...

  8. 9 CFR 381.413 - Nutrient content claims; general principles.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... formulas and medical foods, as described in 21 CFR 101.13(q)(4). (5) (6) Nutrient content claims that were...; (B) Fruits and vegetables; (C) Milk, yogurt, and cheese; (D) Meat, poultry, fish, dry beans, eggs...)(E) of this section. (A) Bread, cereal, rice, and pasta; (B) Fruits and vegetables; (C) Milk,...

  9. 9 CFR 317.313 - Nutrient content claims; general principles.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... formulas and medical foods, as described in 21 CFR 101.13(q)(4). (5) (6) Nutrient content claims that were...; (B) Fruits and vegetables; (C) Milk, yogurt, and cheese; (D) Meat, poultry, fish, dry beans, eggs... section. (A) Bread, cereal, rice, and pasta; (B) Fruits and vegetables; (C) Milk, yogurt, and cheese;...

  10. 9 CFR 317.313 - Nutrient content claims; general principles.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... formulas and medical foods, as described in 21 CFR 101.13(q)(4). (5) (6) Nutrient content claims that were...; (B) Fruits and vegetables; (C) Milk, yogurt, and cheese; (D) Meat, poultry, fish, dry beans, eggs... section. (A) Bread, cereal, rice, and pasta; (B) Fruits and vegetables; (C) Milk, yogurt, and cheese;...

  11. Teaching General Pathology or Principles to Nonveterinary Students.

    ERIC Educational Resources Information Center

    Thomson, R. G.

    1978-01-01

    A survey of many veterinary colleges, agriculture colleges, veterinary science departments, and medical schools to determine the extent to which pathology courses are offered to undergraduate agriculture and science students. Also included is a discussion of the content of courses designed for nonveterinary students and outlines of two such…

  12. Application of ABA Principles to General Communication Instruction.

    ERIC Educational Resources Information Center

    Ogletree, Billy T.; Oren, Thomas

    2001-01-01

    This article examines applied behavior analysis (ABA) based communication instruction for students with autism. It offers an historical context for ABA in speech-language pathology and reviews the literature on the use of ABA as a treatment method for communication impairment in autism, comparing contemporary ABA with the developmental…

  13. 2 CFR Appendix A to Part 230 - General Principles

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... income (i.e., gross income earned from federally-supported activities) see § 215.24 of 2 CFR part 215... but the allocability of costs provisions of Appendix A, subsection C.e. of 2 CFR part 225 (OMB Circular A-87); Appendix A, Section C.4. of 2 CFR part 220 (OMB Circular A-21); Section A.4. of...

  14. 2 CFR Appendix A to Part 230 - General Principles

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... income (i.e., gross income earned from federally-supported activities) see § 215.24 of 2 CFR part 215... but the allocability of costs provisions of Appendix A, subsection C.e. of 2 CFR part 225 (OMB Circular A-87); Appendix A, Section C.4. of 2 CFR part 220 (OMB Circular A-21); Section A.4. of...

  15. 34 CFR 75.530 - General cost principles.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... determining costs applicable to grants and cost-type contracts under grants are specified at 34 CFR 74.27 (for administration of grants to institutions of higher education, and other non-profit organizations) and 34 CFR 80... governments). (Authority: 20 U.S.C. 1221e-3 and 3474) Cross Reference: See 34 CFR part 74, Subpart...

  16. 34 CFR 75.530 - General cost principles.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... determining costs applicable to grants and cost-type contracts under grants are specified at 34 CFR 74.27 (for administration of grants to institutions of higher education, and other non-profit organizations) and 34 CFR 80... governments). (Authority: 20 U.S.C. 1221e-3 and 3474) Cross Reference: See 34 CFR part 74, Subpart...

  17. 34 CFR 75.530 - General cost principles.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... determining costs applicable to grants and cost-type contracts under grants are specified at 34 CFR 74.27 (for administration of grants to institutions of higher education, and other non-profit organizations) and 34 CFR 80... governments). (Authority: 20 U.S.C. 1221e-3 and 3474) Cross reference: See 34 CFR part 74, Subpart...

  18. 34 CFR 75.530 - General cost principles.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... determining costs applicable to grants and cost-type contracts under grants are specified at 34 CFR 74.27 (for administration of grants to institutions of higher education, and other non-profit organizations) and 34 CFR 80... governments). (Authority: 20 U.S.C. 1221e-3 and 3474) Cross reference: See 34 CFR part 74, Subpart...

  19. 34 CFR 75.530 - General cost principles.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... determining costs applicable to grants and cost-type contracts under grants are specified at 34 CFR 74.27 (for administration of grants to institutions of higher education, and other non-profit organizations) and 34 CFR 80... governments). (Authority: 20 U.S.C. 1221e-3 and 3474) Cross reference: See 34 CFR part 74, Subpart...

  20. Generalized uncertainty principle and self-adjoint operators

    SciTech Connect

    Balasubramanian, Venkat; Das, Saurya; Vagenas, Elias C.

    2015-09-15

    In this work we explore the self-adjointness of the GUP-modified momentum and Hamiltonian operators over different domains. In particular, we utilize the theorem by von-Neumann for symmetric operators in order to determine whether the momentum and Hamiltonian operators are self-adjoint or not, or they have self-adjoint extensions over the given domain. In addition, a simple example of the Hamiltonian operator describing a particle in a box is given. The solutions of the boundary conditions that describe the self-adjoint extensions of the specific Hamiltonian operator are obtained.

  1. 9 CFR 381.413 - Nutrient content claims; general principles.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... formulas and medical foods, as described in 21 CFR 101.13(q)(4). (5) (6) Nutrient content claims that were... sodium” or “contains 100 calories.” (2) An implied nutrient content claim is any claim that: (i... false or misleading in any respect (e.g., “100 calories” or “5 grams of fat”), in which case...

  2. 9 CFR 317.313 - Nutrient content claims; general principles.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... formulas and medical foods, as described in 21 CFR 101.13(q)(4). (5) (6) Nutrient content claims that were... product, e.g., “low sodium” or “contains 100 calories.” (2) An implied nutrient content claim is any claim... misleading in any respect (e.g., “100 calories” or “5 grams of fat”), in which case no disclaimer is...

  3. 9 CFR 381.413 - Nutrient content claims; general principles.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... formulas and medical foods, as described in 21 CFR 101.13(q)(4). (5) (6) Nutrient content claims that were... sodium” or “contains 100 calories.” (2) An implied nutrient content claim is any claim that: (i... false or misleading in any respect (e.g., “100 calories” or “5 grams of fat”), in which case...

  4. 9 CFR 317.313 - Nutrient content claims; general principles.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... formulas and medical foods, as described in 21 CFR 101.13(q)(4). (5) (6) Nutrient content claims that were... product, e.g., “low sodium” or “contains 100 calories.” (2) An implied nutrient content claim is any claim... misleading in any respect (e.g., “100 calories” or “5 grams of fat”), in which case no disclaimer is...

  5. 9 CFR 381.413 - Nutrient content claims; general principles.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... formulas and medical foods, as described in 21 CFR 101.13(q)(4). (5) (6) Nutrient content claims that were... sodium” or “contains 100 calories.” (2) An implied nutrient content claim is any claim that: (i... false or misleading in any respect (e.g., “100 calories” or “5 grams of fat”), in which case...

  6. 9 CFR 317.313 - Nutrient content claims; general principles.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... formulas and medical foods, as described in 21 CFR 101.13(q)(4). (5) (6) Nutrient content claims that were... product, e.g., “low sodium” or “contains 100 calories.” (2) An implied nutrient content claim is any claim... misleading in any respect (e.g., “100 calories” or “5 grams of fat”), in which case no disclaimer is...

  7. Relativistic Generalization of the Inertial and Gravitational Masses Equivalence Principle

    NASA Astrophysics Data System (ADS)

    Mitskievich, Nikolai V.

    2008-09-01

    The Newtonian approximation in the gravitational field description not necessarily involves admission of non-relativistic properties of the source terms in Einstein's equations: it is sufficient to merely consider the weak-field condition for gravitational field. When, e.g., a source has electromagnetic nature, one simply cannot ignore its intrinsically relativistic properties, since there cannot be invented any non-relativistic approximation which would adequately describe electromagnetic stress-energy tensor even at large distances where the fields become naturally weak. But the test particle on which gravitational field is acting, should be treated as non-relativistic (this premise is required for introduction of the Newtonian potential ΦN from the geodesic equation).

  8. General Dentist

    MedlinePlus

    ... to your desktop! more... What Is a General Dentist? Article Chapters What Is a General Dentist? General ... Reviewed: January 2012 ?xml:namespace> Related Articles: General Dentists FAGD and MAGD: What Do These Awards Mean? ...

  9. System level electrochemical principles

    NASA Technical Reports Server (NTRS)

    Thaller, L. H.

    1985-01-01

    The traditional electrochemical storage concepts are difficult to translate into high power, high voltage multikilowatt storage systems. The increased use of electronics, and the use of electrochemical couples that minimize the difficulties associated with the corrective measures to reduce the cell to cell capacity dispersion were adopted by battery technology. Actively cooled bipolar concepts are described which represent some attractive alternative system concepts. They are projected to have higher energy densities lower volumes than current concepts. They should be easier to scale from one capacity to another and have a closer cell to cell capacity balance. These newer storage system concepts are easier to manage since they are designed to be a fully integrated battery. These ideas are referred to as system level electrochemistry. The hydrogen-oxygen regenerative fuel cells (RFC) is probably the best example of the integrated use of these principles.

  10. Principles of Induction Accelerators

    NASA Astrophysics Data System (ADS)

    Briggs*, Richard J.

    The basic concepts involved in induction accelerators are introduced in this chapter. The objective is to provide a foundation for the more detailed coverage of key technology elements and specific applications in the following chapters. A wide variety of induction accelerators are discussed in the following chapters, from the high current linear electron accelerator configurations that have been the main focus of the original developments, to circular configurations like the ion synchrotrons that are the subject of more recent research. The main focus in the present chapter is on the induction module containing the magnetic core that plays the role of a transformer in coupling the pulsed power from the modulator to the charged particle beam. This is the essential common element in all these induction accelerators, and an understanding of the basic processes involved in its operation is the main objective of this chapter. (See [1] for a useful and complementary presentation of the basic principles in induction linacs.)

  11. Basic Principles in Oncology

    NASA Astrophysics Data System (ADS)

    Vogl, Thomas J.

    The evolving field of interventional oncology can only be considered as a small integrative part in the complex area of oncology. The new field of interventional oncology needs a standardization of the procedures, the terminology, and criteria to facilitate the effective communication of ideas and appropriate comparison between treatments and new integrative technology. In principle, ablative therapy is a part of locoregional oncological therapy and is defined either as chemical ablation using ethanol or acetic acid, or thermotherapies such as radiofrequency, laser, microwave, and cryoablation. All these new evolving therapies have to be exactly evaluated and an adequate terminology has to be used to define imaging findings and pathology. All the different technologies and evaluated therapies have to be compared, and the results have to be analyzed in order to improve the patient outcome.

  12. Neuronavigation. Principles. Surgical technique.

    PubMed

    Ivanov, Marcel; Ciurea, Alexandru Vlad

    2009-01-01

    Neuronavigation and stereotaxy are techniques designed to help neurosurgeons precisely localize different intracerebral pathological processes by using a set of preoperative images (CT, MRI, fMRI, PET, SPECT etc.). The development of computer assisted surgery was possible only after a significant technological progress, especially in the area of informatics and imagistics. The main indications of neuronavigation are represented by the targeting of small and deep intracerebral lesions and choosing the best way to treat them, in order to preserve the neurological function. Stereotaxis also allows lesioning or stimulation of basal ganglia for the treatment of movement disorders. These techniques can bring an important amount of confort both to the patient and to the neurosurgeon. Neuronavigation was introduced in Romania around 2003, in four neurosurgical centers. We present our five-years experience in neuronavigation and describe the main principles and surgical techniques. PMID:20108488

  13. Dynamical principles in neuroscience

    SciTech Connect

    Rabinovich, Mikhail I.; Varona, Pablo; Selverston, Allen I.; Abarbanel, Henry D. I.

    2006-10-15

    Dynamical modeling of neural systems and brain functions has a history of success over the last half century. This includes, for example, the explanation and prediction of some features of neural rhythmic behaviors. Many interesting dynamical models of learning and memory based on physiological experiments have been suggested over the last two decades. Dynamical models even of consciousness now exist. Usually these models and results are based on traditional approaches and paradigms of nonlinear dynamics including dynamical chaos. Neural systems are, however, an unusual subject for nonlinear dynamics for several reasons: (i) Even the simplest neural network, with only a few neurons and synaptic connections, has an enormous number of variables and control parameters. These make neural systems adaptive and flexible, and are critical to their biological function. (ii) In contrast to traditional physical systems described by well-known basic principles, first principles governing the dynamics of neural systems are unknown. (iii) Many different neural systems exhibit similar dynamics despite having different architectures and different levels of complexity. (iv) The network architecture and connection strengths are usually not known in detail and therefore the dynamical analysis must, in some sense, be probabilistic. (v) Since nervous systems are able to organize behavior based on sensory inputs, the dynamical modeling of these systems has to explain the transformation of temporal information into combinatorial or combinatorial-temporal codes, and vice versa, for memory and recognition. In this review these problems are discussed in the context of addressing the stimulating questions: What can neuroscience learn from nonlinear dynamics, and what can nonlinear dynamics learn from neuroscience?.

  14. Fault Management Guiding Principles

    NASA Technical Reports Server (NTRS)

    Newhouse, Marilyn E.; Friberg, Kenneth H.; Fesq, Lorraine; Barley, Bryan

    2011-01-01

    Regardless of the mission type: deep space or low Earth orbit, robotic or human spaceflight, Fault Management (FM) is a critical aspect of NASA space missions. As the complexity of space missions grows, the complexity of supporting FM systems increase in turn. Data on recent NASA missions show that development of FM capabilities is a common driver for significant cost overruns late in the project development cycle. Efforts to understand the drivers behind these cost overruns, spearheaded by NASA's Science Mission Directorate (SMD), indicate that they are primarily caused by the growing complexity of FM systems and the lack of maturity of FM as an engineering discipline. NASA can and does develop FM systems that effectively protect mission functionality and assets. The cost growth results from a lack of FM planning and emphasis by project management, as well the maturity of FM as an engineering discipline, which lags behind the maturity of other engineering disciplines. As a step towards controlling the cost growth associated with FM development, SMD has commissioned a multi-institution team to develop a practitioner's handbook representing best practices for the end-to-end processes involved in engineering FM systems. While currently concentrating primarily on FM for science missions, the expectation is that this handbook will grow into a NASA-wide handbook, serving as a companion to the NASA Systems Engineering Handbook. This paper presents a snapshot of the principles that have been identified to guide FM development from cradle to grave. The principles range from considerations for integrating FM into the project and SE organizational structure, the relationship between FM designs and mission risk, and the use of the various tools of FM (e.g., redundancy) to meet the FM goal of protecting mission functionality and assets.

  15. General anesthesia

    MedlinePlus

    ... up tired and groggy in the recovery or operating room. You may also feel sick to your ... 3. Sherwood ER, Williams CG, Prough DS. Anesthesiology principles, pain management, and conscious sedation. In: Townsend CM, ...

  16. What is the outcome of applying principlism?

    PubMed

    Hine, Kristen

    2011-12-01

    The four principles approach to bioethics, an approach most associated with the work of Tom Beauchamp and James Childress, is supposed to provide a framework for reasoning through moral issues in medicine. One might wonder, if one were to guide one's thinking by the method suggested by principlism, will one identify and perform the objectively morally right action? Will one's decision making be justified, and consequently, will the action that flows from that decision itself be justified? In this paper, I show that principlism can, and has been, characterized in these two different ways. I also argue that when it is understood according to the first characterization, the view cannot be put into practice. However, when it is understood as an account of justification, there is reason to think that it is indeed action-guiding. Given the problems that confront the first version of the view, perhaps it is best to understand principlism, and biomedical ethical theories generally, not as action-guiding theories of right action, but rather, as procedures by which one's decisions and actions in medicine can achieve a reasonable degree of moral justification. PMID:21710224

  17. Principles of effective performance measurement

    SciTech Connect

    Stevens, D.F.

    1996-07-01

    As with any endeavor connected with trendy words and phrases, {open_quotes}performance measurement{close_quotes} means different things to different people. To some, performance means {open_quotes}customer satisfaction{close_quotes}, and little, if anything, else. To others, it is productivity; to still others, it is procedural. In most real-world situations there are elements of all three of these dimensions. Whatever your definition of performance, it is important that it be clear in your own mind what you are trying to achieve, and that you make sure that those working with and for you have the same understanding. This paper is written from the point of view that performance is primarily productivity; after acceptable productivity is achieved, performance is customer satisfaction. I consider performance to be procedural only insofar as necessary to maintain legality and propriety. Rather than adopting the standard bureaucratic approach to procedure (i.e., everything not required is forbidden), I believe that consistently excellent performance demands the complementary philosophy: everything not forbidden is permitted. Remember: wars are won by the general who knows when to break the rules. The principles enunciated below are not unique to DOE or to the office environment: They are applicable to any performance measurement program. I have tried, however, to provide examples that apply to the office or that are likely to be familiar to those of us working with office information technology today.

  18. Culturing conceptions: From first principles

    NASA Astrophysics Data System (ADS)

    Roth, Wolff-Michael; Lee, Yew Jin; Hwang, Sungwon

    2008-07-01

    Over the past three decades, science educators have accumulated a vast amount of information on conceptions--variously defined as beliefs, ontologies, cognitive structures, mental models, or frameworks--that generally (at least initially) have been derived from interviews about certain topics. During the same time period, cultural studies has emerged as a field in which everyday social practices are interrogated with the objective to understand culture in all its complexity. Science educators have however yet to ask themselves what it would mean to consider the possession of conceptions as well as conceptual change from the perspective of cultural studies. The purpose of this article is thus to articulate in and through the analysis of an interview about natural phenomenon the first principles of such a cultural approach to scientific conceptions. Our bottom-up approach in fact leads us to develop the kind of analyses and theories that have become widespread in cultural studies. This promises to generate less presupposing and more parsimonious explanations of this core issue within science education than if conceptions are supposed to be structures inhabiting the human mind.

  19. Design principles for riboswitch function.

    PubMed

    Beisel, Chase L; Smolke, Christina D

    2009-04-01

    Scientific and technological advances that enable the tuning of integrated regulatory components to match network and system requirements are critical to reliably control the function of biological systems. RNA provides a promising building block for the construction of tunable regulatory components based on its rich regulatory capacity and our current understanding of the sequence-function relationship. One prominent example of RNA-based regulatory components is riboswitches, genetic elements that mediate ligand control of gene expression through diverse regulatory mechanisms. While characterization of natural and synthetic riboswitches has revealed that riboswitch function can be modulated through sequence alteration, no quantitative frameworks exist to investigate or guide riboswitch tuning. Here, we combined mathematical modeling and experimental approaches to investigate the relationship between riboswitch function and performance. Model results demonstrated that the competition between reversible and irreversible rate constants dictates performance for different regulatory mechanisms. We also found that practical system restrictions, such as an upper limit on ligand concentration, can significantly alter the requirements for riboswitch performance, necessitating alternative tuning strategies. Previous experimental data for natural and synthetic riboswitches as well as experiments conducted in this work support model predictions. From our results, we developed a set of general design principles for synthetic riboswitches. Our results also provide a foundation from which to investigate how natural riboswitches are tuned to meet systems-level regulatory demands. PMID:19381267

  20. Design principles underlying circadian clocks.

    PubMed Central

    Rand, D. A.; Shulgin, B. V.; Salazar, D.; Millar, A. J.

    2004-01-01

    A fundamental problem for regulatory networks is to understand the relation between form and function: to uncover the underlying design principles of the network. Circadian clocks present a particularly interesting instance, as recent work has shown that they have complex structures involving multiple interconnected feedback loops with both positive and negative feedback. While several authors have speculated on the reasons for this, a convincing explanation is still lacking.We analyse both the flexibility of clock networks and the relationships between various desirable properties such as robust entrainment, temperature compensation, and stability to environmental variations and parameter fluctuations. We use this to argue that the complexity provides the flexibility necessary to simultaneously attain multiple key properties of circadian clocks. As part of our analysis we show how to quantify the key evolutionary aims using infinitesimal response curves, a tool that we believe will be of general utility in the analysis of regulatory networks. Our results suggest that regulatory and signalling networks might be much less flexible and of lower dimension than their apparent complexity would suggest. PMID:16849158

  1. Principles of Naval Engineering.

    ERIC Educational Resources Information Center

    Naval Personnel Program Support Activity, Washington, DC.

    Fundamentals of shipboard machinery, equipment, and engineering plants are presented in this text prepared for engineering officers. A general description is included of the development of naval ships, ship design and construction, stability and buoyancy, and damage and casualty control. Engineering theories are explained on the background of ship…

  2. Energy conservation principles

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This paper and presentation discuss preliminary findings from energy audits conducted in cotton gins in six states including the allocation of motor horse power and kilowatt hours energy consumption per bale. General inferences will be drawn from information collected at gin plants of various bale...

  3. Using Principles of Programmed Instruction

    ERIC Educational Resources Information Center

    Huffman, Harry

    1971-01-01

    Although programmed instruction in accounting is available, it is limited in scope and in acceptance. Teachers, however, may apply principles of programming to the individualizing of instruction. (Author)

  4. Principles of alternative gerontology

    PubMed Central

    Bilinski, Tomasz; Bylak, Aneta; Zadrag-Tecza, Renata

    2016-01-01

    Surveys of taxonomic groups of animals have shown that contrary to the opinion of most gerontologists aging is not a genuine trait. The process of aging is not universal and its mechanisms have not been widely conserved among species. All life forms are subject to extrinsic and intrinsic destructive forces. Destructive effects of stochastic events are visible only when allowed by the specific life program of an organism. Effective life programs of immortality and high longevity eliminate the impact of unavoidable damage. Organisms that are capable of agametic reproduction are biologically immortal. Mortality of an organism is clearly associated with terminal specialisation in sexual reproduction. The longevity phenotype that is not accompanied by symptoms of senescence has been observed in those groups of animals that continue to increase their body size after reaching sexual maturity. This is the result of enormous regeneration abilities of both of the above-mentioned groups. Senescence is observed when: (i) an organism by principle switches off the expression of existing growth and regeneration programs, as in the case of imago formation in insect development; (ii) particular programs of growth and regeneration of progenitors are irreversibly lost, either partially or in their entirety, in mammals and birds. “We can't solve problems by using the same kind of thinking we used when we created them.” (Ascribed to Albert Einstein) PMID:27017907

  5. Principles of alternative gerontology.

    PubMed

    Bilinski, Tomasz; Bylak, Aneta; Zadrag-Tecza, Renata

    2016-04-01

    Surveys of taxonomic groups of animals have shown that contrary to the opinion of most gerontologists aging is not a genuine trait. The process of aging is not universal and its mechanisms have not been widely conserved among species. All life forms are subject to extrinsic and intrinsic destructive forces. Destructive effects of stochastic events are visible only when allowed by the specific life program of an organism. Effective life programs of immortality and high longevity eliminate the impact of unavoidable damage. Organisms that are capable of agametic reproduction are biologically immortal. Mortality of an organism is clearly associated with terminal specialisation in sexual reproduction. The longevity phenotype that is not accompanied by symptoms of senescence has been observed in those groups of animals that continue to increase their body size after reaching sexual maturity. This is the result of enormous regeneration abilities of both of the above-mentioned groups. Senescence is observed when: (i) an organism by principle switches off the expression of existing growth and regeneration programs, as in the case of imago formation in insect development; (ii) particular programs of growth and regeneration of progenitors are irreversibly lost, either partially or in their entirety, in mammals and birds. PMID:27017907

  6. Principles of Bioremediation Assessment

    NASA Astrophysics Data System (ADS)

    Madsen, E. L.

    2001-12-01

    Although microorganisms have successfully and spontaneously maintained the biosphere since its inception, industrialized societies now produce undesirable chemical compounds at rates that outpace naturally occurring microbial detoxification processes. This presentation provides an overview of both the complexities of contaminated sites and methodological limitations in environmental microbiology that impede the documentation of biodegradation processes in the field. An essential step toward attaining reliable bioremediation technologies is the development of criteria which prove that microorganisms in contaminated field sites are truly active in metabolizing contaminants of interest. These criteria, which rely upon genetic, biochemical, physiological, and ecological principles and apply to both in situ and ex situ bioremediation strategies include: (i) internal conservative tracers; (ii) added conservative tracers; (iii) added radioactive tracers; (iv) added isotopic tracers; (v) stable isotopic fractionation patterns; (vi) detection of intermediary metabolites; (vii) replicated field plots; (viii) microbial metabolic adaptation; (ix) molecular biological indicators; (x) gradients of coreactants and/or products; (xi) in situ rates of respiration; (xii) mass balances of contaminants, coreactants, and products; and (xiii) computer modeling that incorporates transport and reactive stoichiometries of electron donors and acceptors. The ideal goal is achieving a quantitative understanding of the geochemistry, hydrogeology, and physiology of complex real-world systems.

  7. Great Lakes Literacy Principles

    NASA Astrophysics Data System (ADS)

    Fortner, Rosanne W.; Manzo, Lyndsey

    2011-03-01

    Lakes Superior, Huron, Michigan, Ontario, and Erie together form North America's Great Lakes, a region that contains 20% of the world's fresh surface water and is home to roughly one quarter of the U.S. population (Figure 1). Supporting a $4 billion sport fishing industry, plus $16 billion annually in boating, 1.5 million U.S. jobs, and $62 billion in annual wages directly, the Great Lakes form the backbone of a regional economy that is vital to the United States as a whole (see http://www.miseagrant.umich.edu/downloads/economy/11-708-Great-Lakes-Jobs.pdf). Yet the grandeur and importance of this freshwater resource are little understood, not only by people in the rest of the country but also by many in the region itself. To help address this lack of knowledge, the Centers for Ocean Sciences Education Excellence (COSEE) Great Lakes, supported by the U.S. National Science Foundation and the National Oceanic and Atmospheric Administration, developed literacy principles for the Great Lakes to serve as a guide for education of students and the public. These “Great Lakes Literacy Principles” represent an understanding of the Great Lakes' influences on society and society's influences on the Great Lakes.

  8. Principles and the Development of Physical Theory: Case Studies

    NASA Astrophysics Data System (ADS)

    Hovis, Robert Corby

    Three separate articles make up the chapters of this dissertation. They were written with different aims and audiences in mind, but each deals in some way with one or more "principles" that have been invoked in argumentation and explanation in the physical sciences. The principles of concern are propositions which have an "aesthetic" or "foundational" or "philosophical" character and which are (or have been) generally believed to be widely applicable or particularly powerful--for example, the Principle of Plenitude, the Principle of Mathematical Beauty, Occam's Razor, the Cosmological Principle, and the Copernican Principle. Chapter 1 provides an overview of the nature and uses of principles in scientific reasoning and examines in some detail the use of the Principle of Plenitude in the introduction of "tachyons" (faster-than-light particles) into theoretical physics during the 1960s. Chapter 2 is a short biography of P. A. M. Dirac (1902-1984), one of the founders of quantum mechanics, who believed that the Principle of Mathematical Beauty should serve as physicists' guide to truth. Chapter 3 traces the history of the idea of faster-than-light particles in physics since the late 1800s; this idea matured with the rise of the subfield of tachyon physics in the 1960s, and (as mentioned above) physicists appealed to the Principle of Plenitude to argue for the existence of the particles, which are still only hypothetical. According to the thesis developed in these chapters, the epistemological status of principles has evolved over the history of science. While they were once hallowed as a priori truths, in modern science they have increasingly been employed critically, in light of the results of scientific inquiry. That is, science has moved toward making principles testable, subject to rejection or revision, on a par with other scientific propositions.

  9. Generalized Communities in Networks.

    PubMed

    Newman, M E J; Peixoto, Tiago P

    2015-08-21

    A substantial volume of research is devoted to studies of community structure in networks, but communities are not the only possible form of large-scale network structure. Here, we describe a broad extension of community structure that encompasses traditional communities but includes a wide range of generalized structural patterns as well. We describe a principled method for detecting this generalized structure in empirical network data and demonstrate with real-world examples how it can be used to learn new things about the shape and meaning of networks. PMID:26340218

  10. Generalized Communities in Networks

    NASA Astrophysics Data System (ADS)

    Newman, M. E. J.; Peixoto, Tiago P.

    2015-08-01

    A substantial volume of research is devoted to studies of community structure in networks, but communities are not the only possible form of large-scale network structure. Here, we describe a broad extension of community structure that encompasses traditional communities but includes a wide range of generalized structural patterns as well. We describe a principled method for detecting this generalized structure in empirical network data and demonstrate with real-world examples how it can be used to learn new things about the shape and meaning of networks.

  11. Science and Students with Mild Disabilities: Principles of Universal Design.

    ERIC Educational Resources Information Center

    Cawley, John F.; Foley, Teresa E.; Miller, James

    2003-01-01

    This article proposes incorporating principles of universal design into elementary school science programming. Advantages include increasing access to the general education curriculum, enhancing student progress in science, and framing the general education curriculum to make it more appropriate for students with disabilities. Of five models of…

  12. Non-differentiable variational principles

    NASA Astrophysics Data System (ADS)

    Cresson, Jacky

    2005-07-01

    We develop a calculus of variations for functionals which are defined on a set of non-differentiable curves. We first extend the classical differential calculus in a quantum calculus, which allows us to define a complex operator, called the scale derivative, which is the non-differentiable analogue of the classical derivative. We then define the notion of extremals for our functionals and obtain a characterization in term of a generalized Euler-Lagrange equation. We finally prove that solutions of the Schrödinger equation can be obtained as extremals of a non-differentiable variational principle, leading to an extended Hamilton's principle of least action for quantum mechanics. We compare this approach with the scale relativity theory of Nottale, which assumes a fractal structure of space-time.Résumé (Principes variationnels non différentiable). Nous développons un calcul des variations pour des fonctionnelles définies sur un ensemble de courbes non différentiables. Pour cela, nous étendons le calcul différentiel classique, en calcul appelé calcul quantique, qui nous permet de définir un opérateur à valeur complexes, appelé dérivée d'échelle, qui est l'analogue non différentiable de la dérivée usuelle. On définit alors la notion d'extremale pour ces fonctionnelles pour lesquelles nous obtenons une caractérisation via une équation d'Euler-Lagrange généralisée. On prouve enfin que les solutions de l'équation de Schrödinger peuvent s'obtenir comme solution d'un problème variationnel non différentiable, étendant ainsi le principe de moindre action de Hamilton au cadre de la mécanique quantique. On discute enfin la connexion entre ce travail et la théorie de la relativité d'échelle développée par Nottale, et qui suppose une structure fractale de l'espace-temps.

  13. Physical Principles of Evolution

    NASA Astrophysics Data System (ADS)

    Schuster, Peter

    Theoretical biology is incomplete without a comprehensive theory of evolution, since evolution is at the core of biological thought. Evolution is visualized as a migration process in genotype or sequence space that is either an adaptive walk driven by some fitness gradient or a random walk in the absence of (sufficiently large) fitness differences. The Darwinian concept of natural selection consisting in the interplay of variation and selection is based on a dichotomy: All variations occur on genotypes whereas selection operates on phenotypes, and relations between genotypes and phenotypes, as encapsulated in a mapping from genotype space into phenotype space, are central to an understanding of evolution. Fitness is conceived as a function of the phenotype, represented by a second mapping from phenotype space into nonnegative real numbers. In the biology of organisms, genotype-phenotype maps are enormously complex and relevant information on them is exceedingly scarce. The situation is better in the case of viruses but so far only one example of a genotype-phenotype map, the mapping of RNA sequences into RNA secondary structures, has been investigated in sufficient detail. It provides direct information on RNA selection in vitro and test-tube evolution, and it is a basis for testing in silico evolution on a realistic fitness landscape. Most of the modeling efforts in theoretical and mathematical biology today are done by means of differential equations but stochastic effects are of undeniably great importance for evolution. Population sizes are much smaller than the numbers of genotypes constituting sequence space. Every mutant, after all, has to begin with a single copy. Evolution can be modeled by a chemical master equation, which (in principle) can be approximated by a stochastic differential equation. In addition, simulation tools are available that compute trajectories for master equations. The accessible population sizes in the range of 10^7le Nle 10

  14. Principles of ecosystem sustainability

    SciTech Connect

    Chapin, F.S. III; Torn, M.S.; Tateno, Masaki

    1996-12-01

    Many natural ecosystems are self-sustaining, maintaining an characteristic mosaic of vegetation types of hundreds to thousands of years. In this article we present a new framework for defining the conditions that sustain natural ecosystems and apply these principles to sustainability of managed ecosystems. A sustainable ecosystem is one that, over the normal cycle of disturbance events, maintains its characteristics diversity of major functional groups, productivity, and rates of biogeochemical cycling. These traits are determined by a set of four {open_quotes}interactive controls{close_quotes} (climate, soil resource supply, major functional groups of organisms, and disturbance regime) that both govern and respond to ecosystem processes. Ecosystems cannot be sustained unless the interactive controls oscillate within stable bounds. This occurs when negative feedbacks constrain changes in these controls. For example, negative feedbacks associated with food availability and predation often constrain changes in the population size of a species. Linkages among ecosystems in a landscape can contribute to sustainability by creating or extending the feedback network beyond a single patch. The sustainability of managed systems can be increased by maintaining interactive controls so that they form negative feedbacks within ecosystems and by using laws and regulations to create negative feedbacks between ecosystems and human activities, such as between ocean ecosystems and marine fisheries. Degraded ecosystems can be restored through practices that enhance positive feedbacks to bring the ecosystem to a state where the interactive controls are commensurate with desired ecosystem characteristics. The possible combinations of interactive controls that govern ecosystem traits are limited by the environment, constraining the extent to which ecosystems can be managed sustainably for human purposes. 111 refs., 3 figs., 2 tabs.

  15. Generalized higher gauge theory

    NASA Astrophysics Data System (ADS)

    Ritter, Patricia; Sämann, Christian; Schmidt, Lennart

    2016-04-01

    We study a generalization of higher gauge theory which makes use of generalized geometry and seems to be closely related to double field theory. The local kinematical data of this theory is captured by morphisms of graded manifolds between the canonical exact Courant Lie 2-algebroid T M ⊕ T ∗ M over some manifold M and a semistrict gauge Lie 2-algebra. We discuss generalized curvatures and infinitesimal gauge transformations. Finite gauge transformation as well as global kinematical data are then obtained from principal 2-bundles over 2-spaces. As dynamical principle, we consider first the canonical Chern-Simons action for such a gauge theory. We then show that a previously proposed 3-Lie algebra model for the six-dimensional (2,0) theory is very naturally interpreted as a generalized higher gauge theory.

  16. The base rate principle and the fairness principle in social judgment.

    PubMed

    Cao, Jack; Banaji, Mahzarin R

    2016-07-01

    Meet Jonathan and Elizabeth. One person is a doctor and the other is a nurse. Who is the doctor? When nothing else is known, the base rate principle favors Jonathan to be the doctor and the fairness principle favors both individuals equally. However, when individuating facts reveal who is actually the doctor, base rates and fairness become irrelevant, as the facts make the correct answer clear. In three experiments, explicit and implicit beliefs were measured before and after individuating facts were learned. These facts were either stereotypic (e.g., Jonathan is the doctor, Elizabeth is the nurse) or counterstereotypic (e.g., Elizabeth is the doctor, Jonathan is the nurse). Results showed that before individuating facts were learned, explicit beliefs followed the fairness principle, whereas implicit beliefs followed the base rate principle. After individuating facts were learned, explicit beliefs correctly aligned with stereotypic and counterstereotypic facts. Implicit beliefs, however, were immune to counterstereotypic facts and continued to follow the base rate principle. Having established the robustness and generality of these results, a fourth experiment verified that gender stereotypes played a causal role: when both individuals were male, explicit and implicit beliefs alike correctly converged with individuating facts. Taken together, these experiments demonstrate that explicit beliefs uphold fairness and incorporate obvious and relevant facts, but implicit beliefs uphold base rates and appear relatively impervious to counterstereotypic facts. PMID:27325760

  17. The Seven Cardinal Principles Revisited

    ERIC Educational Resources Information Center

    Shane, Harold G.

    1976-01-01

    The seven cardinal principles of education as stated in 1918--health, command of fundamental processes; worthy home membership, vocation; citizenship, use of leisure, and ethical character--were reassessed by panelists and the future development of each principle examined in the light of a changing world. (JD)

  18. Multimedia Principle in Teaching Lessons

    ERIC Educational Resources Information Center

    Kari Jabbour, Khayrazad

    2012-01-01

    Multimedia learning principle occurs when we create mental representations from combining text and relevant graphics into lessons. This article discusses the learning advantages that result from adding multimedia learning principle into instructions; and how to select graphics that support learning. There is a balance that instructional designers…

  19. Children's Understanding of Conversational Principles.

    ERIC Educational Resources Information Center

    Conti, Daniel J.; Camras, Linda A.

    1984-01-01

    Investigates the development of awareness of conversational principles in preschool, first-, and third-grade children by presenting them with short stories ending with a verbal statement by a story character. Results suggest that children's understanding of conversational principles improves considerably between preschool and first grade.…

  20. Ideario Educativo (Principles of Education).

    ERIC Educational Resources Information Center

    Consejo Nacional Tecnico de la Educacion (Mexico).

    This document is an English-language abstract (approximately 1,500 words) which discusses an overall educational policy for Mexico based on Constitutional principles and those of humanism. The basic principles that should guide Mexican education as seen by the National Technical Council for Education are the following: (1) love of country; (2)…

  1. Principles of Play for Soccer

    ERIC Educational Resources Information Center

    Ouellette, John

    2004-01-01

    Soccer coaches must understand the principles of play if they want to succeed. The principles of play are the rules of action that support the basic objectives of soccer and the foundation of a soccer coaching strategy. They serve as a set of permanent criteria that coaches can use to evaluate the efforts of their team. In this article, the author…

  2. Meaty Principles for Environmental Educators.

    ERIC Educational Resources Information Center

    Rockcastle, V. N.

    1985-01-01

    Suggests that educated persons should be exposed to a body of conceptual knowledge which includes basic principles of the biological and physical sciences. Practical examples involving force, sound, light, waves, and density of water are cited. A lesson on animal tracks using principles of force and pressure is also described. (DH)

  3. Hamilton's principle in stochastic mechanics

    NASA Astrophysics Data System (ADS)

    Pavon, Michele

    1995-12-01

    In this paper we establish three variational principles that provide new foundations for Nelson's stochastic mechanics in the case of nonrelativistic particles without spin. The resulting variational picture is much richer and of a different nature with respect to the one previously considered in the literature. We first develop two stochastic variational principles whose Hamilton-Jacobi-like equations are precisely the two coupled partial differential equations that are obtained from the Schrödinger equation (Madelung equations). The two problems are zero-sum, noncooperative, stochastic differential games that are familiar in the control theory literature. They are solved here by means of a new, absolutely elementary method based on Lagrange functionals. For both games the saddle-point equilibrium solution is given by the Nelson's process and the optimal controls for the two competing players are precisely Nelson's current velocity v and osmotic velocity u, respectively. The first variational principle includes as special cases both the Guerra-Morato variational principle [Phys. Rev. D 27, 1774 (1983)] and Schrödinger original variational derivation of the time-independent equation. It also reduces to the classical least action principle when the intensity of the underlying noise tends to zero. It appears as a saddle-point action principle. In the second variational principle the action is simply the difference between the initial and final configurational entropy. It is therefore a saddle-point entropy production principle. From the variational principles it follows, in particular, that both v(x,t) and u(x,t) are gradients of appropriate principal functions. In the variational principles, the role of the background noise has the intuitive meaning of attempting to contrast the more classical mechanical features of the system by trying to maximize the action in the first principle and by trying to increase the entropy in the second. Combining the two variational

  4. Quantum Superposition, Collapse, and the Default Specification Principle

    NASA Astrophysics Data System (ADS)

    Nikkhah Shirazi, Armin

    2014-03-01

    Quantum Superposition and collapse lie at the heart of the difficulty in understanding what quantum mechanics is exactly telling us about reality. We present here a principle which permits one to formulate a simple and general mathematical model that abstracts these features out of quantum theory. A precise formulation of this principle in terms of a set-theoretic axiom added to standard set theory may directly connect the foundations of physics to the foundations of mathematics.

  5. The duality principle and inversion of Laplace-Stielties transforms

    NASA Astrophysics Data System (ADS)

    Pavelyev, A. G.

    2016-04-01

    The fundamental relation between the Laplace transform, the Stielties transform, and the generalized integral equation of refraction is revealed, and a duality principle is formulated for the solution of inverse problems of radio physics. New formulas of the Laplace-transform inversion satisfying the duality principle are obtained. There is no necessity of contour integration in a complex plane for the relations found, which considerably simplifies the reconstruction of originals and makes it possible to control systematic errors in the experimental data.

  6. On Mach's principle

    NASA Astrophysics Data System (ADS)

    Assis, A. K. T.

    1989-08-01

    We propose the postulate that the resultant force acting on any body is zero. With this postulate and with a Weber force law for gravitation, we obtain equations of motion and conclude that all inertial forces are due to gravitational interaction with other bodies in the universe, as suggested by Mach. We then obtain the same value for the advance of the perhelion of the planets as is given by general relativity. All this is accomplished in a strictly relational theory. Finally, we relate these points to topical questions of electrodynamics raised by the experimental studies of Graneau and Pappas.

  7. An Inconvenient Principle

    NASA Astrophysics Data System (ADS)

    Bellac, Michel Le

    2014-11-01

    At the end of the XIXth century, physics was dominated by two main theories: classical (or Newtonian) mechanics and electromagnetism. To be entirely correct, we should add thermodynamics, which seemed to be grounded on different principles, but whose links with mechanics were progressively better understood thanks to the work of Maxwell and Boltzmann, among others. Classical mechanics, born with Galileo and Newton, claimed to explain the motion of lumps of matter under the action of forces. The paradigm for a lump of matter is a particle, or a corpuscle, which one can intuitively think of as a billiard ball of tiny dimensions, and which will be dubbed a micro-billiard ball in what follows. The second main component of XIXth century physics, electromagnetism, is a theory of the electric and magnetic fields and also of optics, thanks to the synthesis between electromagnetism and optics performed by Maxwell, who understood that light waves are nothing other than a particular case of electromagnetic waves. We had, on the one hand, a mechanical theory where matter exhibiting a discrete character (particles) was carried along well localized trajectories and, on the other hand, a wave theory describing continuous phenomena which did not involve transport of matter. The two theories addressed different domains, the only obvious link being the law giving the force on a charged particle submitted to an electromagnetic field, or Lorentz force. In 1905, Einstein put an end to this dichotomic wave/particle view and launched two revolutions of physics: special relativity and quantum physics. First, he showed that Newton's equations of motion must be modified when the particle velocities are not negligible with respect to that of light: this is the special relativity revolution, which introduces in mechanics a quantity characteristic of optics, the velocity of light. However, this is an aspect of the Einsteinian revolution which will not interest us directly, with the exception

  8. Cosmological implications of the Machian principle.

    PubMed

    Fahr, Hans J; Zoennchen, Jochen H

    2006-12-01

    The famous idea of Ernst Mach concerning the non-absolute but relational character of particle inertia is taken up in this paper and is reinvestigated with respect to its cosmological implications. From Thirring's general relativistic study of the old Newtonian problem of the relativity of rotations in different reference systems, it appears that the equivalence principle with respect to rotating reference systems, if at all, can only be extended to the system of the whole universe, if the mass of the universe scales with the effective radius or extent of the universe. A reanalysis of Thirring's derivations still reveals this astonishing result, and thus the general question must be posed: how serious this result has to be taken with respect to cosmological implications. As we will show, the equivalence principle is, in fact, fulfilled by a universe with vanishing curvature, i.e. with a curvature parameter k = 0, which just has the critical density rho (crit) = (3H)(2)/8piG, where H is the Hubble constant. It turns out, however, that this principle can only permanently be fulfilled in an evolving cosmos, if the cosmic mass density, different from its conventional behaviour, varies with the reciprocal of the squared cosmic scale. This, in fact, would automatically be realized, if the mass of each cosmic particle scales with the scale of the universe. The latter fact, on one hand, is a field-theoretical request from a general relativistic field theory which fulfills H. Weyl's requirement of a conformal scale invariance. On the other hand, it can perhaps also be concluded on purely physical grounds, when taking into account that as source of the cosmic metrics only an effective mass density can be taken. This mass density represents the bare mass density reduced by its mass equivalent of gravitational self-binding energy. Some interesting cosmological conclusions connected with this fact are pointed out in this paper. PMID:16944092

  9. Cosmological implications of the Machian principle

    NASA Astrophysics Data System (ADS)

    Fahr, Hans J.; Zoennchen, Jochen H.

    2006-12-01

    The famous idea of Ernst Mach concerning the non-absolute but relational character of particle inertia is taken up in this paper and is reinvestigated with respect to its cosmological implications. From Thirring’s general relativistic study of the old Newtonian problem of the relativity of rotations in different reference systems, it appears that the equivalence principle with respect to rotating reference systems, if at all, can only be extended to the system of the whole universe, if the mass of the universe scales with the effective radius or extent of the universe. A reanalysis of Thirring’s derivations still reveals this astonishing result, and thus the general question must be posed: how serious this result has to be taken with respect to cosmological implications. As we will show, the equivalence principle is, in fact, fulfilled by a universe with vanishing curvature, i.e. with a curvature parameter k = 0, which just has the critical density ρ _{{crit}} = {3H2 } {8π G}, where H is the Hubble constant. It turns out, however, that this principle can only permanently be fulfilled in an evolving cosmos, if the cosmic mass density, different from its conventional behaviour, varies with the reciprocal of the squared cosmic scale. This, in fact, would automatically be realized, if the mass of each cosmic particle scales with the scale of the universe. The latter fact, on one hand, is a field-theoretical request from a general relativistic field theory which fulfills H. Weyl’s requirement of a conformal scale invariance. On the other hand, it can perhaps also be concluded on purely physical grounds, when taking into account that as source of the cosmic metrics only an effective mass density can be taken. This mass density represents the bare mass density reduced by its mass equivalent of gravitational self-binding energy. Some interesting cosmological conclusions connected with this fact are pointed out in this paper.

  10. Principles and techniques for designing precision machines

    SciTech Connect

    Hale, L C

    1999-02-01

    This thesis is written to advance the reader's knowledge of precision-engineering principles and their application to designing machines that achieve both sufficient precision and minimum cost. It provides the concepts and tools necessary for the engineer to create new precision machine designs. Four case studies demonstrate the principles and showcase approaches and solutions to specific problems that generally have wider applications. These come from projects at the Lawrence Livermore National Laboratory in which the author participated: the Large Optics Diamond Turning Machine, Accuracy Enhancement of High- Productivity Machine Tools, the National Ignition Facility, and Extreme Ultraviolet Lithography. Although broad in scope, the topics go into sufficient depth to be useful to practicing precision engineers and often fulfill more academic ambitions. The thesis begins with a chapter that presents significant principles and fundamental knowledge from the Precision Engineering literature. Following this is a chapter that presents engineering design techniques that are general and not specific to precision machines. All subsequent chapters cover specific aspects of precision machine design. The first of these is Structural Design, guidelines and analysis techniques for achieving independently stiff machine structures. The next chapter addresses dynamic stiffness by presenting several techniques for Deterministic Damping, damping designs that can be analyzed and optimized with predictive results. Several chapters present a main thrust of the thesis, Exact-Constraint Design. A main contribution is a generalized modeling approach developed through the course of creating several unique designs. The final chapter is the primary case study of the thesis, the Conceptual Design of a Horizontal Machining Center.

  11. Principles of Pharmacotherapy: I. Pharmacodynamics

    PubMed Central

    Pallasch, Thomas J.

    1988-01-01

    This paper and the ensuing series present the principles guiding and affecting the ability of drugs to produce therapeutic benefit or untoward harm. The principles of pharmacodynamics and pharmacokinetics, the physiologic basis of adverse drug reactions and suitable antidotal therapy, and the biologic basis of drug allergy, drug-drug interactions, pharmacogenetics, teratology and hematologic reactions to chemicals are explored. These principles serve to guide those administering and using drugs to attain the maximum benefit and least attendant harm from their use. Such is the goal of rational therapeutics. PMID:3046440

  12. The uncertainty principle and quantum chaos

    NASA Technical Reports Server (NTRS)

    Chirikov, Boris V.

    1993-01-01

    The conception of quantum chaos is described in some detail. The most striking feature of this novel phenomenon is that all the properties of classical dynamical chaos persist here but, typically, on the finite and different time scales only. The ultimate origin of such a universal quantum stability is in the fundamental uncertainty principle which makes discrete the phase space and, hence, the spectrum of bounded quantum motion. Reformulation of the ergodic theory, as a part of the general theory of dynamical systems, is briefly discussed.

  13. Duality in a maximum generalized entropy model

    NASA Astrophysics Data System (ADS)

    Eguchi, Shinto; Komori, Osamu; Ohara, Atsumi

    2015-01-01

    This paper discusses a possible generalization for the maximum entropy principle. A class of generalized entropy is introduced by that of generator functions, in which the maximum generalized distribution model is explicitly derived including q-Gaussian distributions, Wigner semicircle distributions and Pareto distributions. We define a totally geodesic subspace in the total space of all probability density functions in a framework of information geometry. The model of maximum generalized entropy distributions is shown to be totally geodesic. The duality of the model and the estimation in the maximum generalized principle is elucidated to give intrinsic understandings from the point of information geometry.

  14. Epigenetics: Principles and Practice

    PubMed Central

    Hamilton, James P.

    2011-01-01

    Epigenetics is defined as heritable changes in gene expression that are, unlike mutations, not attributable to alterations in the sequence of DNA. The predominant epigenetic mechanisms are DNA methylation, modifications to chromatin, loss of imprinting and non-coding RNA. Epigenetic regulation of gene expression appears to have long-term effects and wide-ranging effects on health. Diet and environmental exposures may potentially alter the level and scope of epigenetic regulation, thus interesting developments in the study of epigenetics might explain correlations that researchers have found between lifestyle and risk of disease. Aberrant epigenetic patterns have been linked to a number of digestive diseases including Barrett's esophagus, cirrhosis, inflammatory bowel disease, and numerous gastrointestinal malignancies. In fact, many exciting discoveries about epigenetics in general have been made by studying diseases of the gastrointestinal tract and hepatobiliary tree. Epigenetic modifications of DNA in cancer and precancerous lesions offer hope and the promise of novel biomarkers for early cancer detection, prediction, prognosis, and response to treatment. Furthermore, reversal of epigenetic changes represents a potential target of novel therapeutic strategies and medication design. In the future, it is anticipated that innovative diagnostic tests, treatment regimens, and even lifestyle modifications will be based on epigenetic mechanisms and be incorporated into the practice of medicine. PMID:21734376

  15. Principles of allocation of health care resources.

    PubMed Central

    Knox, E G

    1978-01-01

    The methods and principles of allocating centrally provided health care resources to regions and areas are reviewed using the report of the Resource Allocation Working Party (RAWP) (Department of Health and Social Security, 1976) and the consultative document (Department of Health and Social Security, 1976a) as a basis. A range of practical problems arising from these papers (especially the report of the RAWP) is described and traced to the terms of reference. It is concluded that the RAWP misinterpreted aspects of social and administrative reality, and it failed to recognise clearly that the several principles on which it had to work conflicted with each other and demanded decisions of priority. The consequential errors led to (a) an injudicious imposition of 'objectivity' at all levels of allocation, (b) an unjustified insistence that the same method be used at each administrative level in an additive and transitive manner, (c) the exclusion of general practitioner services from their considerations, (d) a failure to delineate those decisions which are in fact political decisions, thus to concatenate them, inappropriately, with technical and professional issues. The main requirement in a revised system is for a mechanism which allocates different priorities to different principles at each appropriate administrative and distributive level, and adapts the working methods of each tier to meet separately defined objectives. PMID:262585

  16. Economic principles motivating social attention in humans.

    PubMed

    Hayden, Benjamin Y; Parikh, Purak C; Deaner, Robert O; Platt, Michael L

    2007-07-22

    We know little about the processes by which we evaluate the opportunity to look at another person. We propose that behavioural economics provides a powerful approach to understanding this basic aspect of social attention. We hypothesized that the decision process culminating in attention to another person follows the same economic principles that govern choices about rewards such as food, drinks and money. Specifically, such rewards are discounted as a function of time, are tradable for other rewards, and reinforce work. Behavioural and neurobiological evidence suggests that looking at other people can also be described as rewarding, but to what extent these economic principles apply to social orienting remains unknown. Here, we show that the opportunity to view pictures of the opposite sex is discounted by delay to viewing, substitutes for money and reinforces work. The reward value of photos of the opposite sex varied with physical attractiveness and was greater in men, suggesting differential utility of acquiring visual information about the opposite sex in men and women. Together, these results demonstrate that choosing whom to look at follows a general set of economic principles, implicating shared neural mechanisms in both social and non-social decision making. PMID:17490943

  17. Probing Quantum Violations of the Equivalence Principle

    NASA Astrophysics Data System (ADS)

    Adunas, G. Z.; Rodriguez-Milla, E.; Ahluwalia, D. V.

    2001-02-01

    The joint realm of quantum mechanics and general-relativistic description of gravitation is becoming increasingly accessible to terrestrial experiments and observations. In this essay we study the emerging indications of the violation of equivalence principle (VEP). While the solar neutrino anomaly may find its natural explanation in a VEP, the statistically significant discrepancy observed in the gravitationally induced phases of neutron interferometry seems to be the first indication of a VEP. However, such a view would seem immediately challenged by the atomic interferometry results. The latter experiments see no indications of VEP, in apparent contradiction to the neutron interferometry results. Here we show that these, and related torsion pendulum experiments, probe different aspects of gravity; and that current experimental techniques, when coupled to the solar-neutrino data, may be able to explore quantum mechanically induced violations of the equivalence principle. We predict quantum violation of the equivalence principle (qVEP) for next generation of atomic interferometry experiments. The prediction entails comparing free fall of two different linear superpositions of Cesium atomic states.

  18. A Free Energy Principle for Biological Systems

    PubMed Central

    Karl, Friston

    2012-01-01

    This paper describes a free energy principle that tries to explain the ability of biological systems to resist a natural tendency to disorder. It appeals to circular causality of the sort found in synergetic formulations of self-organization (e.g., the slaving principle) and models of coupled dynamical systems, using nonlinear Fokker Planck equations. Here, circular causality is induced by separating the states of a random dynamical system into external and internal states, where external states are subject to random fluctuations and internal states are not. This reduces the problem to finding some (deterministic) dynamics of the internal states that ensure the system visits a limited number of external states; in other words, the measure of its (random) attracting set, or the Shannon entropy of the external states is small. We motivate a solution using a principle of least action based on variational free energy (from statistical physics) and establish the conditions under which it is formally equivalent to the information bottleneck method. This approach has proved useful in understanding the functional architecture of the brain. The generality of variational free energy minimisation and corresponding information theoretic formulations may speak to interesting applications beyond the neurosciences; e.g., in molecular or evolutionary biology. PMID:23204829

  19. Get Provoked: Applying Tilden's Principles.

    ERIC Educational Resources Information Center

    Shively, Carol A.

    1995-01-01

    This address given to the Division of Interpretation, Yellowstone National Park, Interpretive Training, June 1993, examines successes and failures in interpretive programs for adults and children in light of Tilden's principles. (LZ)

  20. Minimum Principles in Motor Control.

    PubMed

    Engelbrecht, Sascha E.

    2001-06-01

    Minimum (or minimal) principles are mathematical laws that were first used in physics: Hamilton's principle and Fermat's principle of least time are two famous example. In the past decade, a number of motor control theories have been proposed that are formally of the same kind as the minimum principles of physics, and some of these have been quite successful at predicting motor performance in a variety of tasks. The present paper provides a comprehensive review of this work. Particular attention is given to the relation between minimum theories in motor control and those used in other disciplines. Other issues around which the review is organized include: (1) the relation between minimum principles and structural models of motor planning and motor control, (2) the empirically-driven development of minimum principles and the danger of circular theorizing, and (3) the design of critical tests for minimum theories. Some perspectives for future research are discussed in the concluding section of the paper. Copyright 2001 Academic Press. PMID:11401453

  1. 10 CFR 1023.9 - General guidelines.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false General guidelines. 1023.9 Section 1023.9 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) CONTRACT APPEALS Overview: Organization, Functions and Authorities § 1023.9 General guidelines. (a) The principles of this Overview shall apply to all Board functions unless a specific provision of the relevant...

  2. 10 CFR 1023.9 - General guidelines.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false General guidelines. 1023.9 Section 1023.9 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) CONTRACT APPEALS Overview: Organization, Functions and Authorities § 1023.9 General guidelines. (a) The principles of this Overview shall apply to all Board...

  3. Generalized Entropic Uncertainty Relations with Tsallis' Entropy

    NASA Technical Reports Server (NTRS)

    Portesi, M.; Plastino, A.

    1996-01-01

    A generalization of the entropic formulation of the Uncertainty Principle of Quantum Mechanics is considered with the introduction of the q-entropies recently proposed by Tsallis. The concomitant generalized measure is illustrated for the case of phase and number operators in quantum optics. Interesting results are obtained when making use of q-entropies as the basis for constructing generalized entropic uncertainty measures.

  4. Teaching Evolutionary Theory as General Education.

    ERIC Educational Resources Information Center

    Todd, Paul

    1984-01-01

    Provides a rationale for including evolution as part of a college general education curriculum, discussing the content of evolutionary theory, instructional principles, Darwin's contributions, evolution and religion, and the relationship of evolution with current events. (DMM)

  5. Examining the suitability of the principle of subsidiarity for bioethics.

    PubMed

    Kotalik, Jaro

    2010-12-01

    The political and social principle of subsidiarity can be useful as a general principle of bioethics. The principle states that only those decisions and tasks that cannot be effectively decided upon or performed by a supported or subsidized lower level authority ought to be relegated to a more central or higher authority. The concept of subsidiarity has been embedded tacitly in Western political thought for two millennia, but it has been articulated expressly only in the twentieth century. The principle has unique strengths: it is the only principle that addresses the issue of locus of decision making; it is strongly linked to human dignity, democracy, and solidarity; and it can assist in reaching agreements on the common good. There are also potential drawbacks that need to be taken into account when developing rules and guidelines for the principle's application in bioethics. The principle is particularly helpful in public health ethics, but it is also of use in the ethics of personal care and human research ethics. PMID:21338030

  6. Positronium, antihydrogen, light, and the equivalence principle

    NASA Astrophysics Data System (ADS)

    Karshenboim, Savely G.

    2016-07-01

    While discussing a certain generic difference in effects of gravity on particles and antiparticles, various neutral particles (i.e. the particles which are identical with their antiparticles) could be a perfect probe. One such neutral particles is the positronium atom, which has been available for precision experiments for a few decades. The other important neutral particle is the photon. Behavior of light in the presence of a gravitational field has been the key both to build and develop the theory of general relativity and to verify it experimentally. The very idea of antigravity for antimatter strongly contradicts both the principles of general relativity and its experimentally verified consequences. Consideration of existing experimental results on photons and positrons makes antigravity impossible and leads to a conclusion that the deviation of the ratio of acceleration of the free fall of particles and antiparticles cannot exceed the level of 1× {10}-5.

  7. The precautionary principle and ecological hazards of genetically modified organisms.

    PubMed

    Giampietro, Mario

    2002-09-01

    This paper makes three points relevant to the application of the precautionary principle to the regulation of GMOs. i) The unavoidable arbitrariness in the application of the precautionary principle reflects a deeper epistemological problem affecting scientific analyses of sustainability. This requires understanding the difference between the concepts of "risk", "uncertainty" and "ignorance". ii) When dealing with evolutionary processes it is impossible to ban uncertainty and ignorance from scientific models. Hence, traditional risk analysis (probability distributions and exact numerical models) becomes powerless. Other forms of scientific knowledge (general principles or metaphors) may be useful alternatives. iii) The existence of ecological hazards per se should not be used as a reason to stop innovations altogether. However, the precautionary principle entails that scientists move away from the concept of "substantive rationality" (trying to indicate to society optimal solutions) to that of "procedural rationality" (trying to help society to find "satisficing" solutions). PMID:12436844

  8. Principles of Chemistry (by Michael Munowitz)

    NASA Astrophysics Data System (ADS)

    Kovac, Reviewed By Jeffrey

    2000-05-01

    At a time when almost all general chemistry textbooks seem to have become commodities designed by marketing departments to offend no one, it is refreshing to find a book with a unique perspective. Michael Munowitz has written what I can only describe as a delightful chemistry book, full of conceptual insight, that uses a novel and interesting pedagogic strategy. This is a book that has much to recommend it. This is the best-written general chemistry book I have ever read. An editor with whom I have worked recently remarked that he felt his job was to help authors make their writing sing. Well, the writing in Principles of Chemistry sings with the full, rich harmonies and creative inventiveness of the King's Singers or Chanticleer. Here is the first sentence of the introduction: "Central to any understanding of the physical world is one discovery of paramount importance, a truth disarmingly simple yet profound in its implications: matter is not continuous." This is prose to be savored and celebrated. Principles of Chemistry has a distinct perspective on chemistry: the perspective of the physical chemist. The focus is on simplicity, what is common about molecules and reactions; begin with the microscopic and build bridges to the macroscopic. The author's perspective is clear from the organization of the book. After three rather broad introductory chapters, there are four chapters that develop the quantum mechanical theory of atoms and molecules, including a strong treatment of molecular orbital theory. Unlike many books, Principles of Chemistry presents the molecular orbital approach first and introduces valence bond theory later only as an approximation for dealing with more complicated molecules. The usual chapters on descriptive inorganic chemistry are absent (though there is an excellent chapter on organic and biological molecules and reactions as well as one on transition metal complexes). Instead, descriptive chemistry is integrated into the development of

  9. Investigating underlying principles to guide health impact assessment

    PubMed Central

    Fakhri, Ali; Maleki, Mohammadreza; Gohari, Mahmoodreza; Harris, Patrick

    2014-01-01

    Background: Many countries conduct Health Impact Assessment (HIA) of their projects and policies to predict their positive and negative health impacts. In recent years many guides have been developed to inform HIA practice, largely reflecting local developments in HIA. These guides have often been designed for specific contexts and specific need, making the choice between guides difficult. The objective of the current study is to identify underlying principles in order to guide HIA practice in Iran. Methods: This study was conducted in three stages: 1) Studies comparing HIA guidelines were reviewed to identify criteria used for comparison seeking emphasized principles. 2) The HIA characteristics extracted from published papers were categorized in order to determine the principles that could guide HIA practice. 3) Finally, these principles were agreed by experts using nominal group technique. Results: The review of the studies comparing HIA guides demonstrated there are no clear comparison criteria for reviewing HIA guides and no study mentioned HIA principles. Investigating the HIA principles from peer-reviewed papers, we found 14 issues. These were, considering of general features in planning and conducting HIAs such as HIA stream, level, timing and type, considering of the wider socio-political and economic context, considering of economic, technical and legal aspects of HIA and capacities for HIA, rationality and comprehensiveness, using appropriate evidence, elaborating on HIA relation to other forms of Impact Assessment, considering of equity, and encouraging intersectoral and interdisciplinary cooperation, involvement of stakeholders and transparency as underlying principles to guide HIA practice. The results emphasize how critical these technical as well as tactical considerations are in the early scoping step of an HIA which plans the conduct of the HIA in reponse to local contextual issues. Conclusion: Determining the principles of HIA from peer

  10. Principles of Chemistry (by Michael Munowitz)

    NASA Astrophysics Data System (ADS)

    Kovac, Reviewed By Jeffrey

    2000-05-01

    At a time when almost all general chemistry textbooks seem to have become commodities designed by marketing departments to offend no one, it is refreshing to find a book with a unique perspective. Michael Munowitz has written what I can only describe as a delightful chemistry book, full of conceptual insight, that uses a novel and interesting pedagogic strategy. This is a book that has much to recommend it. This is the best-written general chemistry book I have ever read. An editor with whom I have worked recently remarked that he felt his job was to help authors make their writing sing. Well, the writing in Principles of Chemistry sings with the full, rich harmonies and creative inventiveness of the King's Singers or Chanticleer. Here is the first sentence of the introduction: "Central to any understanding of the physical world is one discovery of paramount importance, a truth disarmingly simple yet profound in its implications: matter is not continuous." This is prose to be savored and celebrated. Principles of Chemistry has a distinct perspective on chemistry: the perspective of the physical chemist. The focus is on simplicity, what is common about molecules and reactions; begin with the microscopic and build bridges to the macroscopic. The author's perspective is clear from the organization of the book. After three rather broad introductory chapters, there are four chapters that develop the quantum mechanical theory of atoms and molecules, including a strong treatment of molecular orbital theory. Unlike many books, Principles of Chemistry presents the molecular orbital approach first and introduces valence bond theory later only as an approximation for dealing with more complicated molecules. The usual chapters on descriptive inorganic chemistry are absent (though there is an excellent chapter on organic and biological molecules and reactions as well as one on transition metal complexes). Instead, descriptive chemistry is integrated into the development of

  11. Principles of Virus Structural Organization

    PubMed Central

    Prasad, B.V. Venkataram; Schmid, Michael F

    2013-01-01

    Viruses, the molecular nanomachines infecting hosts ranging from prokaryotes to eukaryotes, come in different sizes, shapes and symmetries. Questions such as what principles govern their structural organization, what factors guide their assembly, how these viruses integrate multifarious functions into one unique structure have enamored researchers for years. In the last five decades, following Caspar and Klug's elegant conceptualization of how viruses are constructed, high resolution structural studies using X-ray crystallography and more recently cryo-EM techniques have provided a wealth of information on structures of variety of viruses. These studies have significantly furthered our understanding of the principles that underlie structural organization in viruses. Such an understanding has practical impact in providing a rational basis for the design and development of antiviral strategies. In this chapter, we review principles underlying capsid formation in a variety of viruses, emphasizing the recent developments along with some historical perspective. PMID:22297509

  12. The 4th Thermodynamic Principle?

    SciTech Connect

    Montero Garcia, Jose de la Luz; Novoa Blanco, Jesus Francisco

    2007-04-28

    It should be emphasized that the 4th Principle above formulated is a thermodynamic principle and, at the same time, is mechanical-quantum and relativist, as it should inevitably be and its absence has been one of main the theoretical limitations of the physical theory until today.We show that the theoretical discovery of Dimensional Primitive Octet of Matter, the 4th Thermodynamic Principle, the Quantum Hexet of Matter, the Global Hexagonal Subsystem of Fundamental Constants of Energy and the Measurement or Connected Global Scale or Universal Existential Interval of the Matter is that it is possible to be arrived at a global formulation of the four 'forces' or fundamental interactions of nature. The Einstein's golden dream is possible.

  13. Principle Paradigms Revisiting the Dublin Core 1:1 Principle

    ERIC Educational Resources Information Center

    Urban, Richard J.

    2012-01-01

    The Dublin Core "1:1 Principle" asserts that "related but conceptually different entities, for example a painting and a digital image of the painting, are described by separate metadata records" (Woodley et al., 2005). While this seems to be a simple requirement, studies of metadata quality have found that cultural heritage…

  14. RPL Dosimetry: Principles and Applications

    SciTech Connect

    Yamamoto, Takayoshi

    2011-05-05

    The principle of radio-photoluminescence (RPL) is applied to the glass dosimeter, which is one of the most excellent solid state dosimeters. The silver activated phosphate glass irradiated with ionizing radiations emits luminescence when exposed to UV light. This phenomenon is called RPL. The most characteristic features of the glass dosimeters are data accumulation and no fading. The basic principle of RPL is described and then how it is applied to the glass dosimeter is explained. Finally some applications of RPL will be introduced.

  15. Three basic principles of success.

    PubMed

    Levin, Roger

    2003-06-01

    Basic business principles all but ensure success when they are followed consistently. Putting strategies, objectives and tactics in place is the first step toward being able to document systems, initiate scripting and improve staff training. Without the basic steps, systems, scripting and training the practice for performance would be hit or miss, at best. More importantly, applying business principles ensures that limited practice resources are dedicated to the achievement of the strategy. By following this simple, three-step process, a dental practice can significantly enhance both financial success and dentist and staff satisfaction. PMID:12839415

  16. An Identification of Earth Science Principles Pertinent to the Junior High School Programs, and an Analysis of the Eighth Grade Alabama Textbooks in Terms of the Principles Contained Therein.

    ERIC Educational Resources Information Center

    Henson, Kenneth Tyrone

    The purpose of this study was to identify the earth science principles pertinent to current programs in general education at the junior high level, and to determine whether selected textbooks provide adequate representation of those principles. There were 121 principles identified as being essential to the understanding of these five earth science…

  17. Legal Principles in Preventing and Responding to School Violence.

    ERIC Educational Resources Information Center

    McCarthy, Martha M.; Webb, L. Dean

    2000-01-01

    School administrators are challenged to maintain the delicate balance between protecting individuals' rights and ensuring the general welfare by maintaining a safe, secure learning environment. Legal principles and precedents governing restrictions on student appearance, privacy and procedural rights, harassment and hate crimes, and suicide are…

  18. Helping Behavior, Dispositional Empathic Concern, and the Principle of Care

    ERIC Educational Resources Information Center

    Wilhelm, Mark Ottoni; Bekkers, Rene

    2010-01-01

    This research investigates the relative strength of two correlates of helping behavior: dispositional empathic concern and a moral principle to care about others. The empathy-helping and care-helping relationships are investigated using data from the General Social Survey, a nationally representative random sample of the U.S. adult population. Ten…

  19. 17 CFR 37.1300 - Core Principle 13-Financial resources.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... resources. 37.1300 Section 37.1300 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SWAP EXECUTION FACILITIES Financial Resources § 37.1300 Core Principle 13—Financial resources. (a) In general. The swap execution facility shall have adequate financial, operational, and managerial...

  20. Dynamic elastic Cournot-Nash principle with memory term

    NASA Astrophysics Data System (ADS)

    Barbagallo, Annamaria

    2013-10-01

    In the paper we consider the dynamic elastic oligopolistic market equilibrium problem in presence of production excesses and show the equivalence between the generalized Cournot-Nash principle and a quasi-variational inequality. Moreover, we present existence and regularity results for equilibrium solutions. Finally, we introduce a long term memory in order to take into account the delay effects in the noncooperative market.