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Sample records for placa vulnerable solitaria

  1. Vulnerability.

    PubMed

    Cunha, Thiago; Garrafa, Volnei

    2016-04-01

    Collating the concepts of vulnerability through five regional perspectives on bioethics from the United States, Europe, Latin America, Africa, and Asia, this article proposes a means of integration between the different approaches in order to seek a theoretical and normative basis for the field of global bioethics. It argues that only through opening continuous, critical, and self-critical dialogue within the international bioethical community will it be possible to achieve a sufficiently global understanding of vulnerability that is capable of identifying the means needed for addressing the conditions that leave certain groups and individuals more susceptible to "wounding" than others. PMID:26957445

  2. "Candidatus Fokinia solitaria", a Novel "Stand-Alone" Symbiotic Lineage of Midichloriaceae (Rickettsiales).

    PubMed

    Szokoli, Franziska; Sabaneyeva, Elena; Castelli, Michele; Krenek, Sascha; Schrallhammer, Martina; Soares, Carlos A G; da Silva-Neto, Inacio D; Berendonk, Thomas U; Petroni, Giulio

    2016-01-01

    Recently, the family Midichloriaceae has been described within the bacterial order Rickettsiales. It includes a variety of bacterial endosymbionts detected in different metazoan host species belonging to Placozoa, Cnidaria, Arthropoda and Vertebrata. Representatives of Midichloriaceae are also considered possible etiological agents of certain animal diseases. Midichloriaceae have been found also in protists like ciliates and amoebae. The present work describes a new bacterial endosymbiont, "Candidatus Fokinia solitaria", retrieved from three different strains of a novel Paramecium species isolated from a wastewater treatment plant in Rio de Janeiro (Brazil). Symbionts were characterized through the full-cycle rRNA approach: SSU rRNA gene sequencing and fluorescence in situ hybridization (FISH) with three species-specific oligonucleotide probes. In electron micrographs, the tiny rod-shaped endosymbionts (1.2 x 0.25-0.35 μm in size) were not surrounded by a symbiontophorous vacuole and were located in the peripheral host cytoplasm, stratified in the host cortex in between the trichocysts or just below them. Frequently, they occurred inside autolysosomes. Phylogenetic analyses of Midichloriaceae apparently show different evolutionary pathways within the family. Some genera, such as "Ca. Midichloria" and "Ca. Lariskella", have been retrieved frequently and independently in different hosts and environmental surveys. On the contrary, others, such as Lyticum, "Ca. Anadelfobacter", "Ca. Defluviella" and the presently described "Ca. Fokinia solitaria", have been found only occasionally and associated to specific host species. These last are the only representatives in their own branches thus far. Present data do not allow to infer whether these genera, which we named "stand-alone lineages", are an indication of poorly sampled organisms, thus underrepresented in GenBank, or represent fast evolving, highly adapted evolutionary lineages. PMID:26731731

  3. Archivo de placas astrométricas del Observatorio de La Plata

    NASA Astrophysics Data System (ADS)

    di Sisto, R.; Orellana, R. B.

    Se ha realizado una base de datos con las placas fotográficas obtenidas con el Astrográfico del Observatorio de La Plata. Se han clasificado un total de 3000 placas obtenidas para asteroides y cometas. El acceso a la base de datos se hará por FTP y la misma contendrá la siguiente información: fecha y tiempo de exposición, coordenadas del centro de placa, tipo de emulsión fotográfica, estado de la placa, objeto fotografiado.

  4. Structure, synthesis and orientation of microfibrils. VI. The role of ions in microfibril deposition in Oocystis solitaria.

    PubMed

    Quader, H; Robinson, D G

    1979-10-01

    The action of a series of chelators, cryptates and ionophores on microfibril deposition and the presence of cortical microtubules in Oocystis solitaria has been investigated. Having a potent inhibitory effect on cellulose synthesis were the calcium ionophores A 23187 and X-537A, the flourescent calcium chelator chlorotetracycline and the cryptates 211 and 221. Only at unphysiological concentrations, e.g. 100 mM or more, were the chelators EDTA and EGTA effective in completely inhibitory cellulose synthesis. A reduction in the rate of cellulose synthesis was observed with the sodium-selectiv ionophore dianemycin. This partial inhibition was independent of the ionophore concentration. Without effect on microfibril deposition were the potassium-selective ionophore valinomycin and cryptate 222. In all cases, whether cellulose synthesis is blocked or not, none of the above agents prevented the reassembly of cortical microtubules when applied during the recovery from colchicine treatment. Destruction of cortical microtubules through the calcium ionophore may be achieved, but only when additional (2 mM) calcium is added to the culture medium. PMID:118010

  5. Vulnerable groups*.

    PubMed

    Pankhurst, A

    1984-09-01

    As a rule, refugees arrive in their host country with a bare minimum of possessions; in this respect every refugee can be classified as vulnerable. However, a certain category is especially at risk, namely those persons who would be considered vulnerable in a "normal society." These people are doubly in need of assistance, firstly, inasmuch as they are refugees and secondly, insofar as they are vulnerable. If these refugees can be helped to overcome (or at least reduce) their handicaps, they can begin to become self-reliant and form an active, productive parts of their community, rather than remaining an extra burden to an already vulnerable part of the society in their country of asylum. Whilst their able-bodied companions work in the fields or the towns, part of this category can be trained and usefully employed in sectors of work that do not require great mobility or physical fitness (such as handicrafts, trade, teaching and services).. PMID:20958575

  6. Medición de placas astrométricas obtenidas con el telescopio Astrográfico de La Plata

    NASA Astrophysics Data System (ADS)

    di Sisto, R. P.; Orellana, R.

    El Observatorio de La Plata cuenta con un gran número de placas de asteroides y cometas obtenidas con el telescopio astrográfico, que cubren gran parte del cielo del hemisferio sur. En 1996 se recopilaron y clasificaron 2187 placas (Beca para estudiantes de la AAA 1996) de las cuales 2031 corresponden a asteroides. Los datos de cada placa se volcaron en una base de datos creada para facilitar su manejo y preservar la información. A partir de este trabajo se revisaron los MPC electrónicos y se identificaron aquellas placas de asteroides pertenecientes a nuestra base de datos cuyos resultados no fueron publicados en los mismos. De un total de 400 placas que no aparecían publicadas sobresalía un paquete constituído por 40 placas obtenidas en 1977. Estas últimas fueron reducidas utilizando las posiciones y movimientos propios de las estrellas de referencia obtenidas del catálogo SAO 2000 dadas para el sistema FK5. Las posiciones calculadas fueron enviadas y publicadas en los Minor Planet Circulars (MPC).

  7. Software Vulnerability Taxonomy Consolidation

    SciTech Connect

    Polepeddi, S

    2004-12-08

    In today's environment, computers and networks are increasing exposed to a number of software vulnerabilities. Information about these vulnerabilities is collected and disseminated via various large publicly available databases such as BugTraq, OSVDB and ICAT. Each of these databases, individually, do not cover all aspects of a vulnerability and lack a standard format among them, making it difficult for end-users to easily compare various vulnerabilities. A central database of vulnerabilities has not been available until today for a number of reasons, such as the non-uniform methods by which current vulnerability database providers receive information, disagreement over which features of a particular vulnerability are important and how best to present them, and the non-utility of the information presented in many databases. The goal of this software vulnerability taxonomy consolidation project is to address the need for a universally accepted vulnerability taxonomy that classifies vulnerabilities in an unambiguous manner. A consolidated vulnerability database (CVDB) was implemented that coalesces and organizes vulnerability data from disparate data sources. Based on the work done in this paper, there is strong evidence that a consolidated taxonomy encompassing and organizing all relevant data can be achieved. However, three primary obstacles remain: lack of referencing a common ''primary key'', un-structured and free-form descriptions of necessary vulnerability data, and lack of data on all aspects of a vulnerability. This work has only considered data that can be unambiguously extracted from various data sources by straightforward parsers. It is felt that even with the use of more advanced, information mining tools, which can wade through the sea of unstructured vulnerability data, this current integration methodology would still provide repeatable, unambiguous, and exhaustive results. Though the goal of coalescing all available data, which would be of use to system administrators, software developers and vulnerability researchers is not yet achieved, this work has resulted in the most exhaustive collection of vulnerability data to date.

  8. What Does Vulnerability Mean?

    ERIC Educational Resources Information Center

    Parley, Fiona F

    2011-01-01

    Protection of those deemed vulnerable has received increasing attention since 2000. This article reports on care staff views of vulnerability using original data from a research study (Parley. "Vulnerability and abuse: an exploration of views of care staff working with people who have learning disabilities," PhD Thesis, 2007) in which care staff…

  9. What Does Vulnerability Mean?

    ERIC Educational Resources Information Center

    Parley, Fiona F

    2011-01-01

    Protection of those deemed vulnerable has received increasing attention since 2000. This article reports on care staff views of vulnerability using original data from a research study (Parley. "Vulnerability and abuse: an exploration of views of care staff working with people who have learning disabilities," PhD Thesis, 2007) in which care staff…

  10. Shared vulnerabilities in research.

    PubMed

    Chwang, Eric

    2014-01-01

    The U.S. Code of Federal Regulations governing federally funded research on human subjects assumes that harmful research is sometimes morally justifiable because the beneficiaries of that research share a particular vulnerability with its subjects. In this article, I argue against this assumption, which occurs in every subpart of the Code of Federal Regulations that deals with specific vulnerable populations (pregnant women, fetuses, neonates, prisoners, and children). I argue that shared vulnerability is no exception to the general principle that harming one person in order to benefit another is no more justifiable if the two people have traits in common. Further, shared vulnerability is not a reasonable proxy for any morally relevant desideratum of research, in particular the desire to benefit the worst off, the desire to avoid exploitation, and the desire to use vulnerable populations in research only when necessary. PMID:25369404

  11. Facility Environmental Vulnerability Assessment

    SciTech Connect

    Van Hoesen, S.D.

    2001-07-09

    From mid-April through the end of June 2001, a Facility Environmental Vulnerability Assessment (FEVA) was performed at Oak Ridge National Laboratory (ORNL). The primary goal of this FEVA was to establish an environmental vulnerability baseline at ORNL that could be used to support the Laboratory planning process and place environmental vulnerabilities in perspective. The information developed during the FEVA was intended to provide the basis for management to initiate immediate, near-term, and long-term actions to respond to the identified vulnerabilities. It was expected that further evaluation of the vulnerabilities identified during the FEVA could be carried out to support a more quantitative characterization of the sources, evaluation of contaminant pathways, and definition of risks. The FEVA was modeled after the Battelle-supported response to the problems identified at the High Flux Beam Reactor at Brookhaven National Laboratory. This FEVA report satisfies Corrective Action 3A1 contained in the Corrective Action Plan in Response to Independent Review of the High Flux Isotope Reactor Tritium Leak at the Oak Ridge National Laboratory, submitted to the Department of Energy (DOE) ORNL Site Office Manager on April 16, 2001. This assessment successfully achieved its primary goal as defined by Laboratory management. The assessment team was able to develop information about sources and pathway analyses although the following factors impacted the team's ability to provide additional quantitative information: the complexity and scope of the facilities, infrastructure, and programs; the significantly degraded physical condition of the facilities and infrastructure; the large number of known environmental vulnerabilities; the scope of legacy contamination issues [not currently addressed in the Environmental Management (EM) Program]; the lack of facility process and environmental pathway analysis performed by the accountable line management or facility owner; and poor facility and infrastructure drawings. The assessment team believes that the information, experience, and insight gained through FEVA will help in the planning and prioritization of ongoing efforts to resolve environmental vulnerabilities at UT-Battelle--managed ORNL facilities.

  12. Fleshing out vulnerability.

    PubMed

    Tavaglione, Nicolas; Martin, Angela K; Mezger, Nathalie; Durieux-Paillard, Sophie; François, Anne; Jackson, Yves; Hurst, Samia A

    2015-02-01

    In the literature on medical ethics, it is generally admitted that vulnerable persons or groups deserve special attention, care or protection. One can define vulnerable persons as those having a greater likelihood of being wronged - that is, of being denied adequate satisfaction of certain legitimate claims. The conjunction of these two points entails what we call the Special Protection Thesis. It asserts that persons with a greater likelihood of being denied adequate satisfaction of their legitimate claims deserve special attention, care or protection. Such a thesis remains vague, however, as long as we do not know what legitimate claims are. This article aims at dispelling this vagueness by exploring what claims we have in relation to health care - thus fleshing out a claim-based conception of vulnerability. We argue that the Special Protection Thesis must be enriched as follows: If individual or group X has a greater likelihood of being denied adequate satisfaction of some of their legitimate claims to (i) physical integrity, (ii) autonomy, (iii) freedom, (iv) social provision, (v) impartial quality of government, (vi) social bases of self-respect or (vii) communal belonging, then X deserves special attention, care or protection. With this improved understanding of vulnerability, vulnerability talk in healthcare ethics can escape vagueness and serve as an adequate basis for practice. PMID:24602115

  13. Threats and vulnerabilities

    NASA Astrophysics Data System (ADS)

    Ahonen, Pasi; Alahuhta, Petteri; Daskala, Barbara; Delaitre, Sabine; Hert, Paul De; Lindner, Ralf; Maghiros, Ioannis; Moscibroda, Anna; Schreurs, Wim; Verlinden, Michiel

    In this chapter, we present a review of threats and vulnerabilities that could afflict society and individuals in the AmI world in the context of the key policy issues of privacy, identity, trust, security and digital divide. We define a threat as the potential for one or more unwanted consequences caused by a circumstance, capability, action or event that could be harmful to a system or person. Threats can be caused naturally, accidentally or intentionally. In essence, a threat is a ubiquitous phenomenon. A vulnerability is a flaw or weakness in a system's design, its implementation, operation or management that could be exploited to violate the system and, consequently, cause a threat. Vulnerabilities may have different dimensions: technical, functional or behavioural.1

  14. Imaging the vulnerable plaque.

    PubMed

    Vancraeynest, David; Pasquet, Agnes; Roelants, Véronique; Gerber, Bernhard L; Vanoverschelde, Jean-Louis J

    2011-05-17

    Cardiovascular diseases are still the primary causes of mortality in the United States and in Western Europe. Arterial thrombosis is triggered by a ruptured atherosclerotic plaque and precipitates an acute vascular event, which is responsible for the high mortality rate. These rupture-prone plaques are called "vulnerable plaques." During the past decades, much effort has been put toward accurately detecting the presence of vulnerable plaques with different imaging techniques. In this review, we provide an overview of the currently available invasive and noninvasive imaging modalities used to detect vulnerable plaques. We will discuss the upcoming challenges in translating these techniques into clinical practice and in assigning them their exact place in the decision-making process. PMID:21565634

  15. Energy vulnerability relationships

    SciTech Connect

    Shaw, B.R.; Boesen, J.L.

    1998-02-01

    The US consumption of crude oil resources has been a steadily growing indicator of the vitality and strength of the US economy. At the same time import diversity has also been a rapidly developing dimension of the import picture. In the early 1970`s, embargoes of crude oil from Organization of Producing and Exporting Countries (OPEC) created economic and political havoc due to a significant lack of diversity and a unique set of economic, political and domestic regulatory circumstances. The continued rise of imports has again led to concerns over the security of our crude oil resource but threats to this system must be considered in light of the diversity and current setting of imported oil. This report develops several important issues concerning vulnerability to the disruption of oil imports: (1) The Middle East is not the major supplier of oil to the United States, (2) The US is not vulnerable to having its entire import stream disrupted, (3) Even in stable countries, there exist vulnerabilities to disruption of the export stream of oil, (4) Vulnerability reduction requires a focus on international solutions, and (5) DOE program and policy development must reflect the requirements of the diverse supply. Does this increasing proportion of imported oil create a {open_quotes}dependence{close_quotes}? Does this increasing proportion of imported oil present a vulnerability to {open_quotes}price shocks{close_quotes} and the tremendous dislocations experienced during the 1970`s? Finally, what is the vulnerability of supply disruptions from the current sources of imported oil? If oil is considered to be a finite, rapidly depleting resource, then the answers to these questions must be {open_quotes}yes.{close_quotes} However, if the supply of oil is expanding, and not limited, then dependence is relative to regional supply sources.

  16. Plutonium Vulnerability Management Plan

    SciTech Connect

    1995-03-01

    This Plutonium Vulnerability Management Plan describes the Department of Energy`s response to the vulnerabilities identified in the Plutonium Working Group Report which are a result of the cessation of nuclear weapons production. The responses contained in this document are only part of an overall, coordinated approach designed to enable the Department to accelerate conversion of all nuclear materials, including plutonium, to forms suitable for safe, interim storage. The overall actions being taken are discussed in detail in the Department`s Implementation Plan in response to the Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 94-1. This is included as Attachment B.

  17. The Strength of Vulnerability

    ERIC Educational Resources Information Center

    Gilliam, Bobby; Franklin, John Travis

    2004-01-01

    Many aspects of our work with at-risk children are spiritual by nature. A whole generation of at-risk children are crying out and asking hard questions. Although we certainly will not have all the answers, a shared experience of the very vulnerability of our human condition can turn this into a strength for us and our children. The authors propose…

  18. Biological Vulnerability to Alcoholism.

    ERIC Educational Resources Information Center

    Schuckit, Marc A.

    1987-01-01

    Reviews the role of biological factors in the risk for alcoholism. Notes the importance of the definition of primary alcoholism and highlights data indicating that this disorder is genetically influenced. In studies of men at high risk for the future development of alcoholism, vulnerability shows up in reactions to ethanol brain wave amplitude and…

  19. Inflammation and plaque vulnerability.

    PubMed

    Hansson, G K; Libby, P; Tabas, I

    2015-11-01

    Atherosclerosis is a maladaptive, nonresolving chronic inflammatory disease that occurs at sites of blood flow disturbance. The disease usually remains silent until a breakdown of integrity at the arterial surface triggers the formation of a thrombus. By occluding the lumen, the thrombus or emboli detaching from it elicits ischaemic symptoms that may be life-threatening. Two types of surface damage can cause atherothrombosis: plaque rupture and endothelial erosion. Plaque rupture is thought to be caused by loss of mechanical stability, often due to reduced tensile strength of the collagen cap surrounding the plaque. Therefore, plaques with reduced collagen content are thought to be more vulnerable than those with a thick collagen cap. Endothelial erosion, on the other hand, may occur after injurious insults to the endothelium instigated by metabolic disturbance or immune insults. This review discusses the molecular mechanisms involved in plaque vulnerability and the development of atherothrombosis. PMID:26260307

  20. Reducing natural disaster vulnerability

    NASA Astrophysics Data System (ADS)

    Zielinski, Sarah

    2006-04-01

    Because poor countries are vulnerable to the impact of natural disasters, the U.K. Department for International Development (DFID) launched on 30 March a new policy to better integrate natural disaster risk reduction into development and humanitarian activities. Gareth Thomas, U.K. development minister, said, ``There is nothing we can do to stop hurricanes, tsunamis, and earthquakes from striking. But what we can do is help put simple measures in place, such as better built houses, schools, and hospitals alongside more high-tech early warning systems to reduce the loss of life.''

  1. Beyond 'vulnerable groups': contexts and dynamics of vulnerability.

    PubMed

    Zarowsky, Christina; Haddad, Slim; Nguyen, Vinh-Kim

    2013-03-01

    This paper reviews approaches to vulnerability in public health, introducing a series of 10 papers addressing vulnerability in health in Africa. We understand vulnerability as simultaneously a condition and a process. Social inequalities are manifest in and exacerbate three key dimensions of vulnerability: the initial level of wellbeing, the degree of exposure to risk, and the capacity to manage risk effectively. We stress the dynamic interactions linking material and social deprivation, poverty, powerlessness and ill health: risks or shocks and their health impacts are intimately interconnected and reinforce each other in a cycle which in the absence of effective interventions, increases vulnerability. An inductive process which does not begin with an a priori definition or measurement of 'vulnerability' and which does not assume the existence of fixed 'vulnerable groups' allowed us both to re-affirm core aspects of existing conceptual frameworks, and to engage in new ways with literature specifically addressing vulnerability and resilience at the population level as well as with literature - for example in ecology, and on the concept of frailty in research on aging - with which researchers on health and poverty in Africa may not be familiar. We invite conceptual and empirical work on vulnerability in complex systems frameworks. These perspectives emphasize contexts and nonlinear causality thus supporting analyses of vulnerability and resilience as both markers and emergent properties of dynamic interactions. We accept a working definition of vulnerability, and recognize that some definable groups of people are more likely than others to suffer harm from exposure to health risks. But we suggest that the real work - at both intellectual and policy/political levels - lies in understanding and responding to the dynamics, meanings and power relations underlying actual instances and processes of vulnerability and harm. PMID:23549696

  2. Common Control System Vulnerability

    SciTech Connect

    Trent Nelson

    2005-12-01

    The Control Systems Security Program and other programs within the Idaho National Laboratory have discovered a vulnerability common to control systems in all sectors that allows an attacker to penetrate most control systems, spoof the operator, and gain full control of targeted system elements. This vulnerability has been identified on several systems that have been evaluated at INL, and in each case a 100% success rate of completing the attack paths that lead to full system compromise was observed. Since these systems are employed in multiple critical infrastructure sectors, this vulnerability is deemed common to control systems in all sectors. Modern control systems architectures can be considered analogous to today's information networks, and as such are usually approached by attackers using a common attack methodology to penetrate deeper and deeper into the network. This approach often is composed of several phases, including gaining access to the control network, reconnaissance, profiling of vulnerabilities, launching attacks, escalating privilege, maintaining access, and obscuring or removing information that indicates that an intruder was on the system. With irrefutable proof that an external attack can lead to a compromise of a computing resource on the organization's business local area network (LAN), access to the control network is usually considered the first phase in the attack plan. Once the attacker gains access to the control network through direct connections and/or the business LAN, the second phase of reconnaissance begins with traffic analysis within the control domain. Thus, the communications between the workstations and the field device controllers can be monitored and evaluated, allowing an attacker to capture, analyze, and evaluate the commands sent among the control equipment. Through manipulation of the communication protocols of control systems (a process generally referred to as ''reverse engineering''), an attacker can then map out the control system processes and functions. With the detailed knowledge of how the control data functions, as well as what computers and devices communicate using this data, the attacker can use a well known Man-in-the-Middle attack to perform malicious operations virtually undetected. The control systems assessment teams have used this method to gather enough information about the system to craft an attack that intercepts and changes the information flow between the end devices (controllers) and the human machine interface (HMI and/or workstation). Using this attack, the cyber assessment team has been able to demonstrate complete manipulation of devices in control systems while simultaneously modifying the data flowing back to the operator's console to give false information of the state of the system (known as ''spoofing''). This is a very effective technique for a control system attack because it allows the attacker to manipulate the system and the operator's situational awareness of the perceived system status. The three main elements of this attack technique are: (1) network reconnaissance and data gathering, (2) reverse engineering, and (3) the Man-in-the-Middle attack. The details of this attack technique and the mitigation techniques are discussed.

  3. Vulnerability and Trustworthiness.

    PubMed

    Barnard, David

    2016-04-01

    Although recent literature on professionalism in healthcare abounds in recommended character traits, attitudes, or behaviors, with a few exceptions, the recommendations are untethered to any serious consideration of the contours and ethical demands of the healing relationship. This article offers an approach based on the professional's commitment to trustworthiness in response to the vulnerability of those seeking professional help. Because our willingness and ability to trust health professionals or healthcare institutions are affected by our personality, culture, race, age, prior experiences with illness and healthcare, and socioeconomic and political circumstances-"the social determinants of trust"-the attitudes and behaviors that actually do gain trust are patient and context specific. Therefore, in addition to the commitment to cultivating attitudes and behaviors that embody trustworthiness, professionalism also includes the commitment to actually gaining a patient's or family's trust by learning, through individualized dialogue, which conditions would win their justified trust, given their particular history and social situation. PMID:26957454

  4. The Vulnerability of Elderly Consumers.

    ERIC Educational Resources Information Center

    McGhee, Jerrie L.

    1983-01-01

    Reviews research on the vulnerability of the elderly to consumer fraud. Patterns of consumption, situational characteristics, education and product knowledge, psychological losses, social isolation, and psychosocial transitions influence the elderly's vulnerability and ability to cope with consumer abuse. Higher educational attainment and greater…

  5. Simulation with PLACA/DPLACA of thermal and mechanical phenomena in monolithic and dispersed fuel plates

    SciTech Connect

    Soba, Alejandro; Denis, Alicia

    2008-07-15

    The codes PLACA and DPLACA simulate the irradiation behavior of fuels for research reactors under normal operation conditions. They represent, respectively, plate-type fuels of the monolithic and dispersed types. Both codes contain about thirty interconnected and mutually dependent models structured in a modular scheme. This characteristic gives to the codes a large versatility. To simulate U-Mo/Al dispersion fuels, where the growth of an interaction layer can provoke uncontrolled swelling, a diffusion model with two moving boundaries has been developed. It assumes that the kinetics of both layer boundaries is determined by diffusion of U and Al through the layer. The codes make possible a detailed simulation of the evolution of the more relevant physical parameters of a fuel plate during its permanence within a reactor. Both codes were applied to simulate irradiation histories for which experimental data are available. The good quality of the codes predictions reveals the correct performance of the models involved and the appropriate coupling of the ensemble. (author)

  6. Cultural vulnerability and professional narratives.

    PubMed

    Gunaratnam, Yasmin

    2011-01-01

    In this article the author draws upon research with palliative care professionals in the United Kingdom to discuss the value of a stance of cultural vulnerability in intercultural care. Cultural vulnerability recognizes the reality, but also the ethical value of uncertainty and not-knowing in care. Attentiveness to professional narratives is advocated as vital in the development of greater understanding of cultural vulnerability and its effects. The role of cultural identifications and the politics of racism in social work narratives is given specific attention. PMID:22150178

  7. The vulnerable and the susceptible.

    PubMed

    Kottow, Michael H

    2003-10-01

    Human beings are essentially vulnerable in the view that their existence qua humans is not given but constructed. This vulnerability received basic protection from the State, expressed in the form of the universal rights all citizens are meant to enjoy. In addition, many individuals fall prey to destitution and deprivation, requiring social action aimed at recognising the specific harms they suffer and providing remedial assistance to palliate or remove their plights. Citizens receive protection against their biologic vulnerability by means of an in rem right to health [care], which is more an attitude of protection than a specific programme. When individuals become susceptible, that is, biologically weak or diseased, they also increase their predisposition to additional harm, and require social actions to treat their demeaned condition. Such assistance takes the form of positive healthcare rights. Research on human beings has been slow to observe that the subjects recruited are susceptible, especially so if research is done in less developed countries. By mislabelling them as vulnerable--a characteristic they share with all humans--sponsors avoid registering the deprivation these people suffer, and the ethical obligation to offer them remedial help. The distinction between vulnerability and susceptibility also marks the difference between being intact but fragile--vulnerable--and being injured and predisposed to compound additional harm--susceptible. Awareness of this difference should give additional force to the rejection of double standards in research ethics. PMID:14959710

  8. Are Vulnerability Disclosure Deadlines Justified?

    SciTech Connect

    Miles McQueen; Jason L. Wright; Lawrence Wellman

    2011-09-01

    Vulnerability research organizations Rapid7, Google Security team, and Zero Day Initiative recently imposed grace periods for public disclosure of vulnerabilities. The grace periods ranged from 45 to 182 days, after which disclosure might occur with or without an effective mitigation from the affected software vendor. At this time there is indirect evidence that the shorter grace periods of 45 and 60 days may not be practical. However, there is strong evidence that the recently announced Zero Day Initiative grace period of 182 days yields benefit in speeding up the patch creation process, and may be practical for many software products. Unfortunately, there is also evidence that the 182 day grace period results in more vulnerability announcements without an available patch.

  9. Identifying and mapping community vulnerability.

    PubMed

    Morrow, B H

    1999-03-01

    Disaster vulnerability is socially constructed, i.e., it arises out of the social and economic circumstances of everyday living. Most often discussed from the perspective of developing nations, this article extends the argument using American demographic trends. Examples from recent disasters, Hurricane Andrew in particular, illustrate how certain categories of people, such as the poor, the elderly, women-headed households and recent residents, are at greater risk throughout the disaster response process. Knowledge of where these groups are concentrated within communities and the general nature of their circumstances is an important step towards effective emergency management. Emergency planners, policy-makers and responding organisations are encouraged to identify and locate high-risk sectors on Community Vulnerability Maps, integrating this information into GIS systems where feasible. Effective disaster management calls for aggressively involving these neighbourhoods and groups at all levels of planning and response, as well as mitigation efforts that address the root causes of vulnerability. PMID:10204285

  10. Molecular Imaging of Plaque Vulnerability

    PubMed Central

    Tavakoli, Sina; Vashist, Aseem; Sadeghi, Mehran M.

    2014-01-01

    Over the past decade significant progress has been made in the development of novel imaging strategies focusing on the biology of the vessel wall for identification of vulnerable plaques. While the majority of these studies are still in the preclinical stage, few techniques (e.g., 18F-FDG and 18F-NaF PET imaging) have already been evaluated in clinical studies with promising results. Here, we will briefly review the pathobiology of atherosclerosis and discuss molecular imaging strategies that have been developed to target these events, with an emphasis on mechanisms that are associated with atherosclerotic plaque vulnerability. PMID:25124827

  11. Food Chain Security and Vulnerability

    NASA Astrophysics Data System (ADS)

    Brunet, Sébastien; Delvenne, Pierre; Claisse, Frédéric

    In our contemporary societies, the food chain could be defined as a macro-technical system, which depends on a wide variety of actors and risks analysis methods. In this contribution, risks related to the food chain are defined in terms of "modern risks" (Beck 1992). The whole national economic sector of food production/distribution is vulnerable to a local accident, which can affect the functioning of food chain, the export programs and even the political system. Such a complex socio-technical environment is undoubtedly vulnerable to intentional act such as terrorism.

  12. REGIONAL VULNERABILITY: A CONCEPTUAL FRAMEWORK

    EPA Science Inventory

    Regional vulnerability assessment, or ReVA, is an approach to place-based ecological risk assessment that is currently under development by the Office of Research and Development of the U.S. Environmental Protection Agency (EPA). The assessment is done at the scale of EPA region...

  13. Vulnerabilities of Academically Gifted Students.

    ERIC Educational Resources Information Center

    Pfeiffer, Steven I.; Stocking, Vicki B.

    2000-01-01

    Gifted students and youth possess a set of personality characteristics that make them uniquely vulnerable. School personnel and parents need to be aware of these risk factors so that they can provide coordinated educational and social opportunities to foster resilience. They must also be ready to offer preventive and therapeutic mental health…

  14. The vulnerable patient with chronic kidney disease.

    PubMed

    Schlieper, Georg; Hess, Katharina; Floege, Jürgen; Marx, Nikolaus

    2016-03-01

    Patients with chronic kidney disease (CKD) exhibit an increased cardiovascular risk. The high susceptibility to cardiovascular disease renders CKD patients 'vulnerable patients'. The overall cardiovascular risk of a vulnerable patient with CKD is determined by the components of the vulnerable myocardium, the vulnerable vessel and the vulnerable blood which in sum contribute to the increased morbidity and mortality risk in CKD patients. Future therapeutic strategies to reduce cardiovascular morbidity and mortality in this high-risk population should address all three aspects of vulnerability in CKD patients. PMID:25744273

  15. Assessing European wild fire vulnerability

    NASA Astrophysics Data System (ADS)

    Oehler, F.; Oliveira, S.; Barredo, J. I.; Camia, A.; Ayanz, J. San Miguel; Pettenella, D.; Mavsar, R.

    2012-04-01

    Wild fire vulnerability is a measure of potential socio-economic damage caused by a fire in a specific area. As such it is an important component of long-term fire risk management, helping policy-makers take informed decisions about adequate expenditures for fire prevention and suppression, and to target those regions at highest risk. This paper presents a first approach to assess wild fire vulnerability at the European level. A conservative approach was chosen that assesses the cost of restoring the previous land cover after a potential fire. Based on the CORINE Land Cover, a restoration cost was established for each land cover class at country level, and an average restoration time was assigned according to the recovery capacity of the land cover. The damage caused by fire was then assessed by discounting the cost of restoring the previous land cover over the restoration period. Three different vulnerability scenarios were considered assuming low, medium and high fire severity causing different levels of damage. Over Europe, the potential damage of wild land fires ranges from 10 - 13, 732 Euro*ha-1*yr-1 for low fire severity, 32 - 45,772 Euro*ha-1*yr-1 for medium fire severity and 54 - 77,812 Euro*ha-1*yr-1 for high fire severity. The least vulnerable are natural grasslands, moors and heathland and sclerophyllous vegetation, while the highest cost occurs for restoring broad-leaved forest. Preliminary validation comparing these estimates with official damage assessments for past fires shows reasonable results. The restoration cost approach allows for a straightforward, data extensive assessment of fire vulnerability at European level. A disadvantage is the inherent simplification of the evaluation procedure with the underestimation of non-markets goods and services. Thus, a second approach has been developed, valuing individual wild land goods and services and assessing their annual flow which is lost for a certain period of time in case of a fire event. However, due to limitations in data availability, this approach of environmental accounting is not fully implemented yet. Keywords: fire vulnerability, damage assessment, land cover restoration, long-term fire risk, European scale

  16. MID-ATLANTIC REGIONAL VULNERABILITY ASSESSMENT

    EPA Science Inventory

    ORD's Regional Vulnerability Assessment (REVA) Program is developing and demonstrating approaches to assess current and future environmental vulnerabilities so that risk management activities can be targeted. The sister program to EMA.P (Environmental Monitoring Assessment Progr...

  17. Vulnerability genes or plasticity genes?

    PubMed Central

    Belsky, J; Jonassaint, C; Pluess, M; Stanton, M; Brummett, B; Williams, R

    2009-01-01

    The classic diathesis–stress framework, which views some individuals as particularly vulnerable to adversity, informs virtually all psychiatric research on behavior–gene–environment (G × E) interaction. An alternative framework of ‘differential susceptibility' is proposed, one which regards those most susceptible to adversity because of their genetic make up as simultaneously most likely to benefit from supportive or enriching experiences—or even just the absence of adversity. Recent G × E findings consistent with this perspective and involving monoamine oxidase-A, 5-HTTLPR (5-hydroxytryptamine-linked polymorphic region polymorphism) and dopamine receptor D4 (DRD4) are reviewed for illustrative purposes. Results considered suggest that putative ‘vulnerability genes' or ‘risk alleles' might, at times, be more appropriately conceptualized as ‘plasticity genes', because they seem to make individuals more susceptible to environmental influences—for better and for worse. PMID:19455150

  18. Spatial differences in drought vulnerability

    NASA Astrophysics Data System (ADS)

    Per?ec Tadi?, M.; Cindi?, K.; Gaji?-?apka, M.; Zaninovi?, K.

    2012-04-01

    Drought causes the highest economic losses among all hydro-meteorological events in Croatia. It is the most frequent hazard, which produces the highest damages in the agricultural sector. The climate assessment in Croatia according to the aridity index (defined as the ratio of precipitation and potential evapotranspiration) shows that the susceptibility to desertification is present in the warm part of the year and it is mostly pronounced in the Adriatic region and the eastern Croatia lowland. The evidence of more frequent extreme drought events in the last decade is apparent. These facts were motivation to study the drought risk assessment in Croatia. One step in this issue is the construction of the vulnerability map. This map is a complex combination of the geomorphologic and climatological inputs (maps) that are presumed to be natural factors which modify the amount of moisture in the soil. In this study, the first version of the vulnerability map is followed by the updated one that additionally includes the soil types and the land use classes. The first input considered is the geomorphologic slope angle calculated from the digital elevation model (DEM). The SRTM DEM of 100 m resolution is used. The steeper slopes are more likely to lose water and to become dryer. The second climatological parameter, the solar irradiation map, gives for the territory of Croatia the maximum irradiation on the coast. The next meteorological parameter that influences the drought vulnerability is precipitation which is in this assessment included through the precipitation variability expressed by the coefficient of variation. Larger precipitation variability is related with the higher drought vulnerability. The preliminary results for Croatia, according to the recommended procedure in the framework of Drought Management Centre for Southeastern Europe (DMCSEE project), show the most sensitive areas to drought in the southern Adriatic coast and eastern continental lowland.

  19. Urban surface temperature vulnerability assessments

    NASA Astrophysics Data System (ADS)

    Jenerette, D.; Buyantuyev, A.; Harlan, S.; Grossman-Clarke, S.; Ruddell, B. L.; Myint, S. W.

    2013-12-01

    Urban surface temperatures vary greatly in space and time. This variation is in part regulated by impervious surface characteristics, vegetation, water availability, and regional climate changes. The effects of urban surface temperature variation can influence distributions of urban risks and when moderated by potential coping can lead to drastically different vulnerabilities. To better understand future vulnerabilities we conducted two analyses focused on the Phoenix, AZ metropolitan region. First, we examined microscale variation in surface temperature patterns and compared these with parcel level variation for a subset of more than 30 neighborhoods. Temperatures of each parcel and different land covers within the parcel were compared within and across neighborhoods. We are linking these data with interviews conducted for a subset of residents within each neighborhood. These studies are showing a strong relationship between neighborhood variation and surface temperature patterns. The second study combined recently developed relationships between vegetation, meteorology, and land surface temperature with future scenarios of climate, land cover, and socioeconomic variation. These scenarios suggest different future trajectories of land surface temperatures depending on interactive changes in these dominant drivers. Together these studies highlight the both the microscale variation and potential future variation in vulnerability to extreme surface temperature in this hot arid metropolitan region.

  20. Measuring vulnerability to disaster displacement

    NASA Astrophysics Data System (ADS)

    Brink, Susan A.; Khazai, Bijan; Power, Christopher; Wenzel, Friedemann

    2015-04-01

    Large scale disasters can cause devastating impacts in terms of population displacement. Between 2008 and 2013, on average 27 million people were displaced annually by disasters (Yonetani 2014). After large events such as hurricane Katrina or the Port-au-Prince earthquake, images of inadequate public shelter and concerns about large scale and often inequitable migration have been broadcast around the world. Population displacement can often be one of the most devastating and visible impacts of a natural disaster. Despite the importance of population displacement in disaster events, measures to understand the socio-economic vulnerability of a community often use broad metrics to estimate the total socio-economic risk of an event rather than focusing on the specific impacts that a community faces in a disaster. Population displacement is complex and multi-causal with the physical impact of a disaster interacting with vulnerability arising from the response, environmental issues (e.g., weather), cultural concerns (e.g., expectations of adequate shelter), and many individual factors (e.g., mobility, risk perception). In addition to the complexity of the causes, population displacement is difficult to measure because of the wide variety of different terms and definitions and its multi-dimensional nature. When we speak of severe population displacement, we may refer to a large number of displaced people, an extended length of displacement or associated difficulties such as poor shelter quality, risk of violence and crime in shelter communities, discrimination in aid, a lack of access to employment or other difficulties that can be associated with large scale population displacement. We have completed a thorough review of the literature on disaster population displacement. Research has been conducted on historic events to understand the types of negative impacts associated with population displacement and also the vulnerability of different groups to these impacts. We aggregate these ideas into a framework of disaster displacement vulnerability that distinguishes between three main aspects of disaster displacement. Disaster displacement can be considered in terms of the number of displaced people and the length of that displacement. However, the literature emphasizes that the severity of disaster displacement can not be measured completely in quantitative terms. Thus, we include a measure representing people who are trapped and unable to leave their homes due to mobility, resources or for other reasons. Finally the third main aspect considers the difficulties that are associated with displacement and reflects the difference between the experiences of those who are displaced into safe and supportive environments as compared to those whose only alternate shelter is dangerous and inadequate for their needs. Finally, we apply the framework to demonstrate a methodology to estimate vulnerability to disaster displacement. Using data from the Global Earthquake Model (GEM) Social and Economic Vulnerability sub-National Database, we generate an index to measure the vulnerability of Japanese prefectures to the dimensions of displacement included in the framework. References Yonitani, M. (2014). Global Estimates 2014: People displaced by disasters. http://www.internal-displacement.org/publications/2014/global-estimates-2014-people-displaced-by-disasters/

  1. Research on security vulnerability of chip

    NASA Astrophysics Data System (ADS)

    Chen, Zhifeng; Li, Qingbao; Li, Zhou

    2013-03-01

    The 21st century is the information era. IC (Integrated Circuit) is the basis of the modern information industry. The security vulnerability or back door of IC is directly related to the entire information system security. From the perspective of information security, security vulnerability of chip is led out through the practical examples and then the importance of security vulnerability of chip is emphasized. By comparing the security vulnerability of chip with the software virus, the characteristics of the chip vulnerabilities are summed up. Moreover, this paper describes the security vulnerability models of different control logic chips, combinational and sequential logic chips models. Finally it puts forward two kinds of detecting methods of security vulnerability of chip against the two models.

  2. Dynamics of immune system vulnerabilities

    NASA Astrophysics Data System (ADS)

    Stromberg, Sean P.

    The adaptive immune system can be viewed as a complex system, which adapts, over time, to reflect the history of infections experienced by the organism. Understanding its operation requires viewing it in terms of tradeoffs under constraints and evolutionary history. It typically displays "robust, yet fragile" behavior, meaning common tasks are robust to small changes but novel threats or changes in environment can have dire consequences. In this dissertation we use mechanistic models to study several biological processes: the immune response, the homeostasis of cells in the lymphatic system, and the process that normally prevents autoreactive cells from entering the lymphatic system. Using these models we then study the effects of these processes interacting. We show that the mechanisms that regulate the numbers of cells in the immune system, in conjunction with the immune response, can act to suppress autoreactive cells from proliferating, thus showing quantitatively how pathogenic infections can suppress autoimmune disease. We also show that over long periods of time this same effect can thin the repertoire of cells that defend against novel threats, leading to an age correlated vulnerability. This vulnerability is shown to be a consequence of system dynamics, not due to degradation of immune system components with age. Finally, modeling a specific tolerance mechanism that normally prevents autoimmune disease, in conjunction with models of the immune response and homeostasis we look at the consequences of the immune system mistakenly incorporating pathogenic molecules into its tolerizing mechanisms. The signature of this dynamic matches closely that of the dengue virus system.

  3. Scenarios for coastal vulnerability assessment

    USGS Publications Warehouse

    Nicholls, Robert J.; Woodroffe, Colin D.; Burkett, Virginia; Hay, John; Wong, Poh Poh; Nurse, Leonard

    2011-01-01

    Coastal vulnerability assessments tend to focus mainly on climate change and especially on sea-level rise. Assessment of the influence of nonclimatic environmental change or socioeconomic change is less well developed and these drivers are often completely ignored. Given that the most profound coastal changes of the twentieth century due to nonclimate drivers are likely to continue through the twenty-first century, this is a major omission. It may result in not only overstating the importance of climate change but also overlooking significant interactions of climate change and other drivers. To support the development of policies relating to climate change and coastal management, integrated assessments of climatic change in coastal areas are required, including the effects of all the relevant drivers. This chapter explores the development of scenarios (or "plausible futures") of relevant climate and nonclimate drivers that can be used for coastal analysis, with an emphasis on the nonclimate drivers. It shows the importance of analyzing the impacts of climate change and sea-level rise in a broader context of coastal change and all its drivers. This will improve the analysis of impacts, key vulnerabilities, and adaptation needs and, hence, inform climate and coastal policy. Stakeholder engagement is important in the development of scenarios, and the underlying assumptions need to be explicit, transparent, and open to scientific debate concerning their uncertainties/realism and likelihood.

  4. Vulnerability of network of networks

    NASA Astrophysics Data System (ADS)

    Havlin, S.; Kenett, D. Y.; Bashan, A.; Gao, J.; Stanley, H. E.

    2014-10-01

    Our dependence on networks - be they infrastructure, economic, social or others - leaves us prone to crises caused by the vulnerabilities of these networks. There is a great need to develop new methods to protect infrastructure networks and prevent cascade of failures (especially in cases of coupled networks). Terrorist attacks on transportation networks have traumatized modern societies. With a single blast, it has become possible to paralyze airline traffic, electric power supply, ground transportation or Internet communication. How, and at which cost can one restructure the network such that it will become more robust against malicious attacks? The gradual increase in attacks on the networks society depends on - Internet, mobile phone, transportation, air travel, banking, etc. - emphasize the need to develop new strategies to protect and defend these crucial networks of communication and infrastructure networks. One example is the threat of liquid explosives a few years ago, which completely shut down air travel for days, and has created extreme changes in regulations. Such threats and dangers warrant the need for new tools and strategies to defend critical infrastructure. In this paper we review recent advances in the theoretical understanding of the vulnerabilities of interdependent networks with and without spatial embedding, attack strategies and their affect on such networks of networks as well as recently developed strategies to optimize and repair failures caused by such attacks.

  5. Metadata for selecting or submitting generic seismic vulnerability functions via GEM's vulnerability database

    USGS Publications Warehouse

    Jaiswal, Kishor

    2013-01-01

    This memo lays out a procedure for the GEM software to offer an available vulnerability function for any acceptable set of attributes that the user specifies for a particular building category. The memo also provides general guidelines on how to submit the vulnerability or fragility functions to the GEM vulnerability repository, stipulating which attributes modelers must provide so that their vulnerability or fragility functions can be queried appropriately by the vulnerability database. An important objective is to provide users guidance on limitations and applicability by providing the associated modeling assumptions and applicability of each vulnerability or fragility function.

  6. Assessing human vulnerability: Daytime residential distribution as a vulnerability indicator

    NASA Astrophysics Data System (ADS)

    Gokesch, Karin; Promper, Catrin; Papathoma-Köhle, Maria; Glade, Thomas

    2014-05-01

    Natural hazard risk management is based on detailed information on potential impacts of natural hazards. Especially concerning fast onset hazards such as flash floods, earthquakes but also debris flows and landslides, knowing potential hotspots of impact to both, assets and human lives is essential. This information is important for emergency management and decision making in the response phase of the disaster management cycle. Emergency managers are in need of information regarding not only the number of humans being potentially affected but also the respective vulnerability of the group affected based on characteristics such as age, income, health condition, mobility, etc. regarding a certain hazard. The analysis presented focuses on the distribution of the population, assuming a certain pattern of people in a certain radius of action. The method applied is based on a regular pattern of movement of different groups of people and a pattern of presence in certain units, e.g. schools, businesses or residential buildings. The distribution is calculated on a minimum of available data including the average household size, as well as information on building types. The study area is located in the Southwest of Lower Austria, Austria. The city of Waidhofen/Ybbs can be regarded as a regional center providing basic infrastructure, shops and schools. The high concentration of buildings combining shops and residential units leads to a high damage potential throughout the whole study area. The presented results indicate the population distribution within the study area on an average working day. It is clear that explicitly high numbers of people are located in specific buildings (e.g. schools and hospitals) which also include highly vulnerable groups especially to fast onset hazards. The results provide emergency services with the information that they need in order to intervene directly where large numbers of victims or people that need to be evacuated are located. In this way, emergency services can focus and prioritize their actions in order to save lives and reduce the number of potential victims.

  7. Measuring and incorporating vulnerability into conservation planning.

    PubMed

    Wilson, Kerrie; Pressey, Robert L; Newton, Adrian; Burgman, Mark; Possingham, Hugh; Weston, Chris

    2005-05-01

    Conservation planning is the process of locating and designing conservation areas to promote the persistence of biodiversity in situ. To do this, conservation areas must be able to mitigate at least some of the proximate threats to biodiversity. Information on threatening processes and the relative vulnerability of areas and natural features to these processes is therefore crucial for effective conservation planning. However, measuring and incorporating vulnerability into conservation planning have been problematic. We develop a conceptual framework of the role of vulnerability assessments in conservation planning and propose a definition of vulnerability that incorporates three dimensions: exposure, intensity, and impact. We review and categorize methods for assessing the vulnerability of areas and the features they contain and identify the relative strengths and weaknesses of each broad approach. Our review highlights the need for further development and evaluation of approaches to assess vulnerability and for comparisons of their relative effectiveness. PMID:15920667

  8. NV: Nessus Vulnerability Visualization for the Web

    SciTech Connect

    Harrison, Lane; Spahn, Riley B; Iannacone, Michael D; Downing, Evan P; Goodall, John R

    2012-01-01

    Network vulnerability is a critical component of network se- curity. Yet vulnerability analysis has received relatively lit- tle attention from the security visualization community. In this paper we describe nv, a web-based Nessus vulnerability visualization. Nv utilizes treemaps and linked histograms to allow system administrators to discover, analyze, and man- age vulnerabilities on their networks. In addition to visual- izing single Nessus scans, nv supports the analysis of sequen- tial scans by showing which vulnerabilities have been fixed, remain open, or are newly discovered. Nv was also designed to operate completely in-browser, to avoid sending sensitive data to outside servers. We discuss the design of nv, as well as provide case studies demonstrating vulnerability analysis workflows which include a multiple-node testbed and data from the 2011 VAST Challenge.

  9. Assessing the Security Vulnerabilities of Correctional Facilities

    SciTech Connect

    Morrison, G.S.; Spencer, D.S.

    1998-10-27

    The National Institute of Justice has tasked their Satellite Facility at Sandia National Laboratories and their Southeast Regional Technology Center in Charleston, South Carolina to devise new procedures and tools for helping correctional facilities to assess their security vulnerabilities. Thus, a team is visiting selected correctional facilities and performing vulnerability assessments. A vulnerability assessment helps to identi~ the easiest paths for inmate escape, for introduction of contraband such as drugs or weapons, for unexpected intrusion fi-om outside of the facility, and for the perpetration of violent acts on other inmates and correctional employees, In addition, the vulnerability assessment helps to quantify the security risks for the facility. From these initial assessments will come better procedures for performing vulnerability assessments in general at other correctional facilities, as well as the development of tools to assist with the performance of such vulnerability assessments.

  10. Mining Bug Databases for Unidentified Software Vulnerabilities

    SciTech Connect

    Dumidu Wijayasekara; Milos Manic; Jason Wright; Miles McQueen

    2012-06-01

    Identifying software vulnerabilities is becoming more important as critical and sensitive systems increasingly rely on complex software systems. It has been suggested in previous work that some bugs are only identified as vulnerabilities long after the bug has been made public. These vulnerabilities are known as hidden impact vulnerabilities. This paper discusses the feasibility and necessity to mine common publicly available bug databases for vulnerabilities that are yet to be identified. We present bug database analysis of two well known and frequently used software packages, namely Linux kernel and MySQL. It is shown that for both Linux and MySQL, a significant portion of vulnerabilities that were discovered for the time period from January 2006 to April 2011 were hidden impact vulnerabilities. It is also shown that the percentage of hidden impact vulnerabilities has increased in the last two years, for both software packages. We then propose an improved hidden impact vulnerability identification methodology based on text mining bug databases, and conclude by discussing a few potential problems faced by such a classifier.

  11. Proliferation Vulnerability Red Team report

    SciTech Connect

    Hinton, J.P.; Barnard, R.W.; Bennett, D.E.

    1996-10-01

    This report is the product of a four-month independent technical assessment of potential proliferation vulnerabilities associated with the plutonium disposition alternatives currently under review by DOE/MD. The scope of this MD-chartered/Sandia-led study was limited to technical considerations that could reduce proliferation resistance during various stages of the disposition processes below the Stored Weapon/Spent Fuel standards. Both overt and covert threats from host nation and unauthorized parties were considered. The results of this study will be integrated with complementary work by others into an overall Nonproliferation and Arms Control Assessment in support of a Secretarial Record of Decision later this year for disposition of surplus U.S. weapons plutonium.

  12. Predicting Vulnerability Risks Using Software Characteristics

    ERIC Educational Resources Information Center

    Roumani, Yaman

    2012-01-01

    Software vulnerabilities have been regarded as one of the key reasons for computer security breaches that have resulted in billions of dollars in losses per year (Telang and Wattal 2005). With the growth of the software industry and the Internet, the number of vulnerability attacks and the ease with which an attack can be made have increased. From…

  13. Design Vulnerability Assessments for Safeguards Sealing Systems

    SciTech Connect

    Brockman, Linda; Johnston, Roger; Kravtchenko, Victor; Undem, Halvor A.; Wishard, Bernard

    2010-08-11

    The International Atomic Energy Agency (the "Agency") engages in a rigorous equipment authorization process prior to deploying Safeguards instrumentation, including Safeguards sealing systems, for world-wide use. A positive result from a vulnerability assessment is one of the many requirements that must be met prior to instrumentation deployment. Given the long time period in the Safeguards instrumentation development cycle, the substantial Member State investments made, and the significant Agency staff time required, a negative result for the vulnerability assessment can result in the loss of time, considerable additional expense, or even the failure to deploy an instrument or sealing system at all. First suggested in 1998 by the General Physics Institute in Moscow, an approach that incorporates a design vulnerability assessment minimizes the risk of deployment failure by teaming a public sector vulnerability assessment team with the instrument or sealing system design team in order to identify, at the earliest possible design stage, inherent vulnerabilities. Involving the vulnerability assessors early and often in the design and development process avoids many of the problems inherent in evaluating security vulnerabilities only after the design is finalized. The disadvantages include increased costs and time to deployment. An improved pressure-sensitive adhesive label seal, called the "VOID-3 seal" was developed for the Agency using this design vulnerability assessment process.

  14. Predicting Vulnerability Risks Using Software Characteristics

    ERIC Educational Resources Information Center

    Roumani, Yaman

    2012-01-01

    Software vulnerabilities have been regarded as one of the key reasons for computer security breaches that have resulted in billions of dollars in losses per year (Telang and Wattal 2005). With the growth of the software industry and the Internet, the number of vulnerability attacks and the ease with which an attack can be made have increased. From…

  15. Infrastructure Vulnerability Assessment Model (I-VAM).

    PubMed

    Ezell, Barry Charles

    2007-06-01

    Quantifying vulnerability to critical infrastructure has not been adequately addressed in the literature. Thus, the purpose of this article is to present a model that quantifies vulnerability. Vulnerability is defined as a measure of system susceptibility to threat scenarios. This article asserts that vulnerability is a condition of the system and it can be quantified using the Infrastructure Vulnerability Assessment Model (I-VAM). The model is presented and then applied to a medium-sized clean water system. The model requires subject matter experts (SMEs) to establish value functions and weights, and to assess protection measures of the system. Simulation is used to account for uncertainty in measurement, aggregate expert assessment, and to yield a vulnerability (Omega) density function. Results demonstrate that I-VAM is useful to decisionmakers who prefer quantification to qualitative treatment of vulnerability. I-VAM can be used to quantify vulnerability to other infrastructures, supervisory control and data acquisition systems (SCADA), and distributed control systems (DCS). PMID:17640208

  16. Amyotrophic lateral sclerosis: cell vulnerability or system vulnerability?

    PubMed Central

    Talbot, Kevin

    2014-01-01

    Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease with clinical, pathological and genetic overlap with frontotemporal dementia (FTD). No longer viewed as one disease with a single unified cause, ALS is now considered to be a clinicopathological syndrome resulting from a complex convergence of genetic susceptibility, age-related loss of cellular homeostasis, and possible environmental influences. The rapid increase in recent years of the number of genes in which mutations have been associated with ALS has led to in vitro and in vivo models that have generated a wealth of data indicating disruption of specific biochemical pathways and sub-cellular compartments. Data implicating pathways including protein misfolding, mRNA splicing, oxidative stress, proteosome and mitochondrial dysfunction in the pathogenesis of ALS reinforce a disease model based on selective age-dependent vulnerability of a specific population of cells. To the clinical neurologist, however, ALS presents as a disease of focal onset and contiguous spread. Characteristic regional patterns of involvement and progression suggest that the disease does not proceed randomly but via a restricted number of anatomical pathways. These clinical observations combined with electrophysiological and brain-imaging studies underpin the concept of ALS at the macroscopic level as a ‘system degeneration’. This dichotomy between cellular and systems neurobiology raises the fundamental questions of what initiates the disease process in a specific anatomical site and how the disease is propagated. Is the essence of ALS a cell-to-cell transmission of pathology with, for example, a ‘prion-like’ mechanism, or does the cellular pathology follow degeneration of specific synaptic networks? Elucidating the interaction between cellular degeneration and system level degeneration will aid modeling of the disease in the earliest phases, improve the development of sensitive markers of disease progression and response to therapy, and expand our understanding of the biological basis of clinical and pathological heterogeneity. PMID:24010870

  17. Vulnerability, Health Agency and Capability to Health.

    PubMed

    Straehle, Christine

    2016-01-01

    One of the defining features of the capability approach (CA) to health, as developed in Venkatapuram's book Health Justice, is its aim to enable individual health agency. Furthermore, the CA to health hopes to provide a strong guideline for assessing the health-enabling content of social and political conditions. In this article, I employ the recent literature on the liberal concept of vulnerability to assess the CA. I distinguish two kinds of vulnerability. Considering circumstantial vulnerability, I argue that liberal accounts of vulnerability concerned with individual autonomy, align with the CA to health. Individuals should, as far as possible, be able to make health-enabling decisions about their lives, and their capability to do so should certainly not be hindered by public policy. The CA to health and a vulnerability-based analysis then work alongside to define moral responsibilities and designate those who hold them. Both approaches demand social policy to address circumstances that hinder individuals from taking health-enabling decisions. A background condition of vulnerability, on the other hand, even though it hampers the capability for health, does not warrant the strong moral claim proposed by the CA to health to define health as a meta-capability that should guide social policy. Nothing in our designing social policy could change the challenge to health agency when we deal with background conditions of vulnerability. PMID:26686329

  18. Determining Vulnerability Importance in Environmental Impact Assessment

    SciTech Connect

    Toro, Javier; Duarte, Oscar; Requena, Ignacio; Zamorano, Montserrat

    2012-01-15

    The concept of vulnerability has been used to describe the susceptibility of physical, biotic, and social systems to harm or hazard. In this sense, it is a tool that reduces the uncertainties of Environmental Impact Assessment (EIA) since it does not depend exclusively on the value assessments of the evaluator, but rather is based on the environmental state indicators of the site where the projects or activities are being carried out. The concept of vulnerability thus reduces the possibility that evaluators will subjectively interpret results, and be influenced by outside interests and pressures during projects. However, up until now, EIA has been hindered by a lack of effective methods. This research study analyzes the concept of vulnerability, defines Vulnerability Importance and proposes its inclusion in qualitative EIA methodology. The method used to quantify Vulnerability Importance is based on a set of environmental factors and indicators that provide a comprehensive overview of the environmental state. The results obtained in Colombia highlight the usefulness and objectivity of this method since there is a direct relation between this value and the environmental state of the departments analyzed. - Research Highlights: Black-Right-Pointing-Pointer The concept of vulnerability could be considered defining Vulnerability Importance included in qualitative EIA methodology. Black-Right-Pointing-Pointer The use of the concept of environmental vulnerability could reduce the subjectivity of qualitative methods of EIA. Black-Right-Pointing-Pointer A method to quantify the Vulnerability Importance proposed provides a comprehensive overview of the environmental state. Black-Right-Pointing-Pointer Results in Colombia highlight the usefulness and objectivity of this method.

  19. Vulnerability indicators of sea water intrusion.

    PubMed

    Werner, Adrian D; Ward, James D; Morgan, Leanne K; Simmons, Craig T; Robinson, Neville I; Teubner, Michael D

    2012-01-01

    In this paper, simple indicators of the propensity for sea water intrusion (SWI) to occur (referred to as "SWI vulnerability indicators") are devised. The analysis is based on an existing analytical solution for the steady-state position of a sharp fresh water-salt water interface. Interface characteristics, that is, the wedge toe location and sea water volume, are used in quantifying SWI in both confined and unconfined aquifers. Rates-of-change (partial derivatives of the analytical solution) in the wedge toe or sea water volume are used to quantify the aquifer vulnerability to various stress situations, including (1) sea-level rise; (2) change in recharge (e.g., due to climate change); and (3) change in seaward discharge. A selection of coastal aquifer cases is used to apply the SWI vulnerability indicators, and the proposed methodology produces interpretations of SWI vulnerability that are broadly consistent with more comprehensive investigations. Several inferences regarding SWI vulnerability arise from the analysis, including: (1) sea-level rise impacts are more extensive in aquifers with head-controlled rather than flux-controlled inland boundaries, whereas the opposite is true for recharge change impacts; (2) sea-level rise does not induce SWI in constant-discharge confined aquifers; (3) SWI vulnerability varies depending on the causal factor, and therefore vulnerability composites are needed that differentiate vulnerability to such threats as sea-level rise, climate change, and changes in seaward groundwater discharge. We contend that the approach is an improvement over existing methods for characterizing SWI vulnerability, because the method has theoretical underpinnings and yet calculations are simple, although the coastal aquifer conceptualization is highly idealized. PMID:21434909

  20. DOE contractor vulnerability analysis: DPA or MAIT

    SciTech Connect

    Six, D.E.; Nichols, D.H.

    1980-01-01

    Two vulnerability analysis techniques, Diversion Path Analysis (DPA) and Matrix Analysis of the Insider Threat (MAIT), were applied by EG and G Idaho, Inc. Safeguards and Security to the same item accountable SNM storage area at INEL. Technical and cost data for each methodology were collected and compared. A recommendation that MAIT be utilized for future vulnerability analyses of item accountable SNM storage and use areas operated by EG and G Idaho for DOE-ID resulted. Unclassified results of the two techniques and MAIT/DPA technical and cost comparisons will be presented which show that MAIT can be used for vulnerability analyses to comply with Department of Energy (DOE) requirements.

  1. Understanding the Code: safeguarding vulnerable adults.

    PubMed

    Griffith, Richard

    2015-11-01

    Under the provisions of the Nursing and Midwifery Council's revised Code (2015) , all district and community nurses have a professional duty to safeguard vulnerable adults from abuse. With adult abuse continuing to increase, all members of the district and community nursing teams are well placed to identify and take action to safeguard the vulnerable. In this article, Richard Griffith explains how the Care Act 2014 seeks to improve the safeguarding of vulnerable adults and the role of district and community nurses in that process. PMID:26551387

  2. Managing risk with climate vulnerability science

    NASA Astrophysics Data System (ADS)

    Stern, Paul C.; Ebi, Kristie L.; Leichenko, Robin; Olson, Richard Stuart; Steinbruner, John D.; Lempert, Robert

    2013-07-01

    Climate information alone cannot be sufficient for anticipating and reducing climate impacts. Enhanced vulnerability science is needed, including local to global monitoring, to support effective anticipatory efforts to increase societal resilience to potentially disruptive events.

  3. Culturally safe research with vulnerable populations.

    PubMed

    Wilson, Denise; Neville, Stephen

    2009-08-01

    Culturally safe research processes, methodologies, and mutually aligned research endeavours are a fundamental right of those being researched. Vulnerable populations are at risk of experiencing inequalities in health experiences and health outcomes, and research beneficial to those being researched is crucial to address disparities. Often vulnerable populations are exposed to research that is driven by dominant epistemologies, research methodologies, and socio-cultural lenses that can exacerbate their vulnerability, negating their socio-cultural reality. In this paper it is contended that researchers should review the way in which research is constructed and developed by creating a culturally safe space for research to occur with those who are vulnerable. A framework based on partnership, participation, protection, and power is presented as a way of creating culturally safe research. PMID:19715497

  4. Housing concerns of vulnerable older Canadians.

    PubMed

    Weeks, Lori E; LeBlanc, Kristal

    2010-09-01

    Preparing for the future housing needs of older adults is imperative in countries with an aging population, but little is known about these issues among vulnerable older adults. This study used a qualitative approach to identify key housing concerns in this group. A total of 84 vulnerable older adults including Aboriginal elders, those with various disabilities, and ethnic minorities participated in 10 focus groups. The Canadian Mortgage and Housing Corporation's (CMHC's) standards of core housing need provided a framework for data analysis, along with the identification of additional key housing themes across and within groups of vulnerable older adults. The results provide insight into preferred housing characteristics, regardless of housing form. Additionally, the results provide insight into how to support vulnerable older adults who choose to remain in their homes and communities and how to help ensure that appropriate housing is developed that meets the needs of this diverse population. PMID:20712917

  5. Ecology: Ecosystem vulnerability to ocean warming

    NASA Astrophysics Data System (ADS)

    Tittensor, Derek P.

    2015-12-01

    Analysis of the temperature ranges occupied by marine species finds that the vulnerability of ecological communities to global warming may depend more on organismal physiology than on the magnitude of change. See Article p.88

  6. [Aged woman's vulnerability related to AIDS].

    PubMed

    Silva, Carla Marins; Lopes, Fernanda Maria do Valle Martins; Vargens, Octavio Muniz da Costa

    2010-09-01

    This article is a systhematic literature review including the period from 1994 to 2009, whose objective was to discuss the aged woman's vulnerability in relation to Acquired Imunodeficiency Syndrome (Aids). The search for scientific texts was accomplished in the following databases: Biblioteca Virtual em Saúde, Scientific Eletronic Library Online (SciELO), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) and Medical Literature Analysis and Retrieval System Online (MEDLINE). The descriptors used were vulnerability, woman and Aids. Eighteen texts were analyzed, including articles in scientific journals, thesis and dissertations. As a conclusion, it was noted that aged women and vulnerability to Aids are directly related, through gender characteristics including submission and that were built historical and socially. We consider as fundamental the development of studies which may generate publications accessible to women, in order to help them see themselves as persons vulnerable to Aids contagion just for being women. PMID:21574329

  7. Salt vulnerability assessment methodology for urban streams

    NASA Astrophysics Data System (ADS)

    Betts, A. R.; Gharabaghi, B.; McBean, E. A.

    2014-09-01

    De-icing agents such as road salts while used for winter road maintenance can cause negative effects on urban stream water quality and drinking water supplies. A new methodology using readily available spatial data to identify Salt Vulnerable Areas (SVAs) for urban streams is used to prioritize implementation of best management practices. The methodology calculates the probable chloride concentration statistics at specified points in the urban stream network and compares the results with known aquatic species exposure tolerance limits to characterize the vulnerability scores. The approach prioritizes implementation of best management practices to areas identified as vulnerable to road salt. The vulnerability assessment is performed on seven sites in four watersheds in the Greater Toronto Area and validated using the Hanlon Creek watershed in Guelph. The mean annual in-stream chloride concentration equation uses readily available spatial data - with province-wide coverage - that can be easily used in any urban watershed.

  8. Camana, Peru, and Tsunami Vulnerability

    NASA Technical Reports Server (NTRS)

    2002-01-01

    A tsunami washed over the low-lying coastal resort region near Camana, southern Peru, following a strong earthquake on June 23, 2001. The earthquake was one of the most powerful of the last 35 years and had a magnitude of 8.4. After the initial quake, coastal residents witnessed a sudden drawdown of the ocean and knew a tsunami was imminent. They had less than 20 minutes to reach higher ground before the tsunami hit. Waves as high as 8 m came in four destructive surges reaching as far as 1.2 km inland. The dashed line marks the approximate area of tsunami inundation. Thousands of buildings were destroyed, and the combined earthquake and tsunami killed as many as 139 people. This image (ISS004-ESC-6128) was taken by astronauts onboard the International Space Station on 10 January 2002. It shows some of the reasons that the Camana area was so vulnerable to tsunami damage. The area has a 1 km band of coastal plain that is less than 5 m in elevation. Much of the plain can be seen by the bright green fields of irrigated agriculture that contrast with the light-colored desert high ground. Many of the tsunami-related deaths were workers in the onion fields in the coastal plain that were unwilling to leave their jobs before the end of the shift. A number of lives were spared because the tsunami occurred during the resort off-season, during the daylight when people could see the ocean drawdown, and during one of the lowest tides of the year. Information on the Tsunami that hit Camana can be found in a reports on the visit by the International Tsunami Survey Team and the USC Tsunami Research Lab. Earthquake Epicenter, Peru shows another image of the area. Image provided by the Earth Sciences and Image Analysis Laboratory at Johnson Space Center. Additional images taken by astronauts and cosmonauts can be viewed at the NASA-JSC Gateway to Astronaut Photography of Earth.

  9. Application of PRA to HEMP vulnerability analysis

    SciTech Connect

    Mensing, R.W.

    1985-09-01

    Vulnerability analyses of large systems, e.g., control and communication centers, aircraft, ships, are subject to many uncertainties. A basic source of uncertainty is the random variation inherent in the physical world. Thus, vulnerability is appropriately described by an estimate of the probability of survival (or failure). A second source of uncertainty that also needs to be recognized is the uncertainty associated with the analysis or estimation process itself. This uncertainty, often called modeling uncertainty, has many contributors. There are the approximations introduced by using mathematical models to describe reality. Also, the appropriate values of the model parameters are derived from several sources, e.g., based on experimental or test data, based on expert judgment and opinion. In any case, these values are subject to uncertainty. This uncertainty must be considered in the description of vulnerability. Thus, the estimate of the probability of survival is not a single value but a range of values. Probabilistic risk analysis (PRA) is a methodology which deals with these uncertainty issues. This report discusses the application of PRA to HEMP vulnerability analyses. Vulnerability analysis and PRA are briefly outlined and the need to distinguish between random variation and modeling uncertainty is discussed. Then a sequence of steps appropriate for applying PRA to vulnerability problems is outlined. Finally, methods for handling modeling uncertainty are identified and discussed.

  10. Global Distributions of Vulnerability to Climate Change

    SciTech Connect

    Yohe, Gary; Malone, Elizabeth L.; Brenkert, Antoinette L.; Schlesinger, Michael; Meij, Henk; Xiaoshi, Xing

    2006-12-01

    Signatories of the United Nations Framework Convention on Climate Change (UNFCCC) have committed themselves to addressing the “specific needs and special circumstances of developing country parties, especially those that are particularly vulnerable to the adverse effects of climate change”.1 The Intergovernmental Panel on Climate Change (IPCC) has since concluded with high confidence that “developing countries will be more vulnerable to climate change than developed countries”.2 In their most recent report, however, the IPCC notes that “current knowledge of adaptation and adaptive capacity is insufficient for reliable prediction of adaptations” 3 because “the capacity to adapt varies considerably among regions, countries and socioeconomic groups and will vary over time”.4 Here, we respond to the apparent contradiction in these two statements by exploring how variation in adaptive capacity and climate impacts combine to influence the global distribution of vulnerability. We find that all countries will be vulnerable to climate change, even if their adaptive capacities are enhanced. Developing nations are most vulnerable to modest climate change. Reducing greenhouse-gas emissions would diminish their vulnerabilities significantly. Developed countries would benefit most from mitigation for moderate climate change. Extreme climate change overwhelms the abilities of all countries to adapt. These findings should inform both ongoing negotiations for the next commitment period of the Kyoto Protocol and emerging plans for implementing UNFCCC-sponsored adaptation funds.

  11. Vulnerability assessment of mining subsidence hazards.

    PubMed

    Deck, Olivier; Verdel, Thierry; Salmon, Romuald

    2009-10-01

    Between 1996 and 1999, five mining subsidence events occurred in the iron-ore field in Lorraine, France, and damaged several hundred buildings. Because of the thousand hectares of undermined areas, an assessment of the vulnerability of buildings and land is necessary for risk management. Risk assessment methods changed from initial risk management decisions that took place immediately after the mining subsidence to the risk assessment studies that are currently under consideration. These changes reveal much about the complexity of the vulnerability concept and about difficulties in developing simple and relevant methods for its assessment. The objective of this article is to present this process, suggest improvements on the basis of theoretical definitions of the vulnerability, and give an operational example of vulnerability assessment in the seismic field. The vulnerability is divided into three components: weakness, stakes value, and resilience. Final improvements take into account these three components and constitute an original method of assessing the vulnerability of a city to subsidence. PMID:19473313

  12. Placas and Murals

    ERIC Educational Resources Information Center

    Romotsky, Jerry; Romotsky, Sally

    1974-01-01

    Presented examples of graffiti as seen in the barrios of East Los Angeles that told of the past and demonstrated how graffiti could be used in a positive fashion reflecting the positive aspirations, interests, and identities of the residents. (Author/RK)

  13. Drought vulnerability assesssment and mapping in Morocco

    NASA Astrophysics Data System (ADS)

    Imani, Yasmina; Lahlou, Ouiam; Bennasser Alaoui, Si; Naumann, Gustavo; Barbosa, Paulo; Vogt, Juergen

    2014-05-01

    Drought vulnerability assessment and mapping in Morocco Authors: Yasmina Imani 1, Ouiam Lahlou 1, Si Bennasser Alaoui 1 Paulo Barbosa 2, Jurgen Vogt 2, Gustavo Naumann 2 1: Institut Agronomique et Vétérinaire Hassan II (IAV Hassan II), Rabat Morocco. 2: European Commission, Joint Research Centre (JRC), Institute for Environment and Sustainability (IES), Ispra, Italy. In Morocco, nearly 50% of the population lives in rural areas. They are mostly small subsistent farmers whose production depends almost entirely on rainfall. They are therefore very sensitive to drought episodes that may dramatically affect their incomes. Although, as a consequence of the increasing frequency, length and severity of drought episodes in the late 90's, the Moroccan government decided, to move on from a crisis to a risk management approach, drought management remains in practice mainly reactive and often ineffective. The lack of effectiveness of public policy is in part a consequence of the poor understanding of drought vulnerability at the rural community level, which prevents the development of efficient mitigation actions and adaptation strategies, tailored to the needs and specificities of each rural community. Thus, the aim of this study is to assess and map drought vulnerability at the rural commune level in the Oum Er-Rbia basin which is a very heterogeneous basin, showing a big variability of climates, landscapes, cropping systems and social habits. Agricultural data collected from the provincial and local administrations of Agriculture and socio-economic data from the National Department of Statistics were used to compute a composite vulnerability index (DVI) integrating four different components: (i) the renewable natural capacity, (ii) the economic capacity, (iii) human and civic resources, and (iv) infrastructure and technology. The drought vulnerability maps that were derived from the computation of the DVI shows that except very specific areas, most of the Oum er Rbia basin is highly vulnerable to drought. The mountainous areas present the most favorable annual rainfall. That contributes to explain their low DVI. In the provinces that present the highest vulnerability to drought, spots presenting a lower vulnerability correspond to large irrigated perimeters. Overall, the main output of this study were to show how the DVI can allow detecting the differences in vulnerability in the different rural communes providing, therefore, a tool for more effective drought management practices. The analysis of the 4 dimensions of the DVI showed that at the river basin level, the mean annual rainfall, the percentage of irrigated lands, The Cereal / Fruit trees and market crops ratio, the land status, the farm's sizes, the adult literacy rate and the access to improved drinking water represent the major drivers of vulnerability. They may therefore be targeted in priority by mitigation and adaptation actions.

  14. Cyber/Physical Security Vulnerability Assessment Integration

    SciTech Connect

    MacDonald, Douglas G.; Clements, Samuel L.; Patrick, Scott W.; Perkins, Casey J.; Muller, George; Lancaster, Mary J.; Hutton, William J.

    2013-02-28

    Securing high value and critical assets is one of the biggest challenges facing this nation and others around the world. In modern integrated systems, there are four potential modes of attack available to an adversary: • physical only attack, • cyber only attack, • physical-enabled cyber attack, • cyber-enabled physical attack. Blended attacks involve an adversary working in one domain to reduce system effectiveness in another domain. This enables the attacker to penetrate further into the overall layered defenses. Existing vulnerability assessment (VA) processes and software tools which predict facility vulnerabilities typically evaluate the physical and cyber domains separately. Vulnerabilities which result from the integration of cyber-physical control systems are not well characterized and are often overlooked by existing assessment approaches. In this paper, we modified modification of the timely detection methodology, used for decades in physical security VAs, to include cyber components. The Physical and Cyber Risk Analysis Tool (PACRAT) prototype illustrates an integrated vulnerability assessment that includes cyber-physical interdependencies. Information about facility layout, network topology, and emplaced safeguards is used to evaluate how well suited a facility is to detect, delay, and respond to attacks, to identify the pathways most vulnerable to attack, and to evaluate how often safeguards are compromised for a given threat or adversary type. We have tested the PACRAT prototype on critical infrastructure facilities and the results are promising. Future work includes extending the model to prescribe the recommended security improvements via an automated cost-benefit analysis.

  15. Vulnerabilities in snakebites in Sao Paulo, Brazil

    PubMed Central

    Bertolozzi, Maria Rita; Scatena, Camila Morato da Conceição; França, Francisco Oscar de Siqueira

    2015-01-01

    ABSTRACT OBJECTIVE To describe elements of vulnerability of victims of snakebite. METHODS This qualitative, descriptive, cross-sectional study had, as theoretical framework, the concept of vulnerability in individual, social, and programmatic dimensions. We interviewed 21 patients admitted into a hospital specialized in the care of accidents caused by venomous animals. The interviews were analyzed according to a discourse analysis technique. RESULTS Patients were mainly young men, living in remote countryside areas, where health services frequently have limited resources. We found social and individual conditions of vulnerability, such as precarious schooling, low professional qualification, housing without access to piped water, no sewage treated, and no regular garbage collection, and lack of knowledge on this health problem. Regarding the programmatic dimension, we found limited accessibility to the health services that could affect the prognosis and the frequency of sequelae and deaths. CONCLUSIONS Considering such vulnerabilities evoke the need to improve the program for control the Accidents by Venomous Animals and the training of health workers, we highlight the potential use of the concept of vulnerability, which may amplify the understanding and the recommendations for the practice and education related to snakebites. PMID:26603351

  16. Creativity and psychopathology: a shared vulnerability model.

    PubMed

    Carson, Shelley H

    2011-03-01

    Creativity is considered a positive personal trait. However, highly creative people have demonstrated elevated risk for certain forms of psychopathology, including mood disorders, schizophrenia spectrum disorders, and alcoholism. A model of shared vulnerability explains the relation between creativity and psychopathology. This model, supported by recent findings from neuroscience and molecular genetics, suggests that the biological determinants conferring risk for psychopathology interact with protective cognitive factors to enhance creative ideation. Elements of shared vulnerability include cognitive disinhibition (which allows more stimuli into conscious awareness), an attentional style driven by novelty salience, and neural hyperconnectivity that may increase associations among disparate stimuli. These vulnerabilities interact with superior meta-cognitive protective factors, such as high IQ, increased working memory capacity, and enhanced cognitive flexibility, to enlarge the range and depth of stimuli available in conscious awareness to be manipulated and combined to form novel and original ideas. PMID:21443821

  17. Nuclear Molecular Imaging for Vulnerable Atherosclerotic Plaques

    PubMed Central

    Lee, Soo Jin

    2015-01-01

    Atherosclerosis is an inflammatory disease as well as a lipid disorder. Atherosclerotic plaque formed in vessel walls may cause ischemia, and the rupture of vulnerable plaque may result in fatal events, like myocardial infarction or stroke. Because morphological imaging has limitations in diagnosing vulnerable plaque, molecular imaging has been developed, in particular, the use of nuclear imaging probes. Molecular imaging targets various aspects of vulnerable plaque, such as inflammatory cell accumulation, endothelial activation, proteolysis, neoangiogenesis, hypoxia, apoptosis, and calcification. Many preclinical and clinical studies have been conducted with various imaging probes and some of them have exhibited promising results. Despite some limitations in imaging technology, molecular imaging is expected to be used both in the research and clinical fields as imaging instruments become more advanced. PMID:26357491

  18. Ethical aspects of vulnerability in research.

    PubMed

    Weisser-Lohmann, Elisabeth

    2012-11-01

    In connection with research on humans, the term "vulnerability" is only appropriate to identify the special need for protection of certain sections of the population and individuals, if this term refers to the additional risk of certain groups of subjects. Authors who focus on the additional risk suffering of a subject group when defining vulnerability succeed in considering the specific worthiness of protection in a context-sensitive way. The attempt to define the risk-benefit assessment for vulnerable subject groups on a binding basis faces considerable difficulties. This assessment depends both on the research situation and on the test subject. The normative aspect of this decision could be solved by referring to Rawl's decision model of an original position. In cases where there is no benefit for the subject, arguments in the discussion of the risks and benefits that are based on a "group or overall benefit" and an "objective interest," cannot be fully sustained. PMID:23205001

  19. Narcissistic grandiosity and narcissistic vulnerability in psychotherapy.

    PubMed

    Pincus, Aaron L; Cain, Nicole M; Wright, Aidan G C

    2014-10-01

    This article briefly summarizes the empirical and clinical literature underlying a contemporary clinical model of pathological narcissism. Unlike the DSM Narcissistic Personality Disorder (NPD), this clinical model identifies and differentiates between two phenotypic themes of dysfunction-narcissistic grandiosity and narcissistic vulnerability-that can be expressed both overtly and covertly in patients' ways of thinking, feeling, behaving, and participating in treatment. Clinical recognition that narcissistic patients can and often do present for psychotherapy in vulnerable states of depression, anxiety, shame, and even suicidality increases the likelihood of accurate diagnosis and effective treatment planning. This article provides case examples derived from psychotherapies with narcissistic patients to demonstrate how narcissistic grandiosity and narcissistic vulnerability concurrently present in patients who seek treatment. PMID:24446581

  20. Assessing species vulnerability to climate change

    NASA Astrophysics Data System (ADS)

    Pacifici, Michela; Foden, Wendy B.; Visconti, Piero; Watson, James E. M.; Butchart, Stuart H. M.; Kovacs, Kit M.; Scheffers, Brett R.; Hole, David G.; Martin, Tara G.; Akçakaya, H. Resit; Corlett, Richard T.; Huntley, Brian; Bickford, David; Carr, Jamie A.; Hoffmann, Ary A.; Midgley, Guy F.; Pearce-Kelly, Paul; Pearson, Richard G.; Williams, Stephen E.; Willis, Stephen G.; Young, Bruce; Rondinini, Carlo

    2015-03-01

    The effects of climate change on biodiversity are increasingly well documented, and many methods have been developed to assess species' vulnerability to climatic changes, both ongoing and projected in the coming decades. To minimize global biodiversity losses, conservationists need to identify those species that are likely to be most vulnerable to the impacts of climate change. In this Review, we summarize different currencies used for assessing species' climate change vulnerability. We describe three main approaches used to derive these currencies (correlative, mechanistic and trait-based), and their associated data requirements, spatial and temporal scales of application and modelling methods. We identify strengths and weaknesses of the approaches and highlight the sources of uncertainty inherent in each method that limit projection reliability. Finally, we provide guidance for conservation practitioners in selecting the most appropriate approach(es) for their planning needs and highlight priority areas for further assessments.

  1. Mapping Regional Drought Vulnerability: a Case Study

    NASA Astrophysics Data System (ADS)

    Karamouz, M.; Zeynolabedin, A.; Olyaei, M. A.

    2015-12-01

    Drought is among the natural disaster that causes damages and affects many people's life in many part of the world including in Iran. Recently, some factors such as climate variability and the impact of climate change have influenced drought frequency and intensity in many parts of the world. Drought can be divided into four categories of meteorological, hydrological, agricultural and social-economic. In meteorological the important feature is lack of rainfall. In hydrological drought river flows and dam storage are considered. Lack of soil moisture is the key factor in agricultural droughts while in social-economic type of drought the relation between supply and demand and social-economic damages due to water deficiency is studied. While the first three types relates to the lack of some hydrological characteristics, social-economic type of drought is actually the consequence of other types expressed in monetary values. Many indices are used in assessing drought; each has its own advantages and disadvantages and can be used for specific types of drought. Therefore knowing the types of drought can provide a better understanding of shortages and their characteristics. Drought vulnerability is a concept which shows the likelihood of damages from hazard in a particular place by focusing on the system status prior to the disaster. Drought vulnerability has been viewed as a potential for losses in the region due to water deficiency at the time of drought. In this study the application of vulnerability concept in drought management in East Azarbaijan province in Iran is investigated by providing vulnerability maps which demonstrates spatial characteristics of drought vulnerability. In the first step, certain governing parameters in drought analysis such as precipitation, temperature, land use, topography, solar radiation and ground water elevation have been investigated in the region. They are described in details and calculated in suitable time series. Vulnerabilities are ranked in 5 intervals and for each parameter vulnerability maps are prepared in GIS environment. Selection of theses parameters are based on factors such as regional features and availability of data. Considering the fact that the aforementioned parameters have different level of importance in vulnerability maps, different weights are assigned to the parameters considering how critical each parameter is in the overall drought analysis. Expert's opinion is selected in assigning weights. A multi-criteria decision making (MCDM) framework is used to check the consistency of the provided information. Then the weighted maps are overlaid to find the overall vulnerability map. The map shows very low, low, medium, intense and very intense regional vulnerabilities. According to the results, the west part of East Azarbaijan province is the most vulnerable region to drought which is expected due to the vicinity of this part to Urumia Lake that has been lost most of its water during the last decades. The least vulnerable part seems to be the Eastern part of the province with longer lasting resources. Taking into consideration that Caspian Sea is near this part with high precipitation record, the outcome of this study is in line with the general expectations. The result of this study can be used for preparedness planning and for allocating resources for facing droughts in this region.

  2. Regional tsunami vulnerability analysis through ASTER imagery

    NASA Astrophysics Data System (ADS)

    Dall'Osso, Filippo; Cavalletti, Alessandra; Immordino, Francesco; Gonella, Marco

    2010-05-01

    Analysis of vulnerability to natural hazards is a key issue of prevention measures within ICZM. Knowledge of susceptibility to damage and how this is distributed along the coast allows to optimize possible prevention and mitigation actions. The present study focuses on tsunami vulnerability of a large extension of coastline: the entire westerly Thailand's coast. The work is a follow up of the CRATER project (Coastal Risk Analysis for Tsunamis and Environmental Remediation) carried out on the aftermath of the 26th December 2004 Tsunami event. Vulnerability is analyzed considering an inundation scenario given by a tsunami of seismic origin, causing a maximum run-up of 25m.. An innovative methodology have been here developed and applied, based on the combined use of ASTER (Advanced Spaceborn Thermal Emission and Reflection Radiometer) satellite imagery, SRTM v-3 (Shuttle Radar Topography Mission - version #3) DEMs and GIS. Vulnerability level has been calculated combining information on coastal geomorphology, land use, topography and distance from the shoreline. Land use has been extrapolated from ASTER images through a multi-spectral analysis (a pixel-based and supervised classification process) of ASTER bands 1 to 9, plus one band for the NDVI index (Normalized Difference Vegetation Index). Coastal geomorphology has been obtained through a photo-interpretation process. Results have been organized in a set of vectorial vulnerability maps with horizontal resolution of 90m. The proposed methodology has the great advantage of being repeatable for any case of vulnerability analysis at small-medium scale (i.e. at Regional/National level) with a moderate investment in term of costs and human resources.

  3. Microbiological Food Safety for Vulnerable People

    PubMed Central

    Lund, Barbara M.

    2015-01-01

    Foodborne pathogens are more likely to cause infection and to result in serious consequences in vulnerable people than in healthy adults. People with some increase in susceptibility may form nearly 20% of the population in the UK and the USA. Conditions leading to increased susceptibility are listed. The main factors leading to foodborne disease caused by major pathogens are outlined and examples are given of outbreaks resulting from these factors. Measures to prevent foodborne disease include procedures based on Hazard Analysis Critical Control Point principles and prerequisite programmes and, especially for vulnerable people, the use of lower-risk foods in place of higher-risk products. PMID:26308030

  4. [Concepts of vulnerability of psychiatric diseases].

    PubMed

    Stamm, R; Bühler, K E

    2001-07-01

    Despite intensive research in recent decades, the search for the aetiopathogenesis of psychiatric diseases is just as relevant as ever. In recent years, ideas of the aetiopathogenesis of psychotic diseases based on the concept of "vulnerability" in its diverse variations and developments have been gained increasingly ground. The publications of Zubin and associates above all have contributed to a "vulnerability model". According to this descriptive model, schizophrenic disturbances develop as a result of stimuli/irritants or stress factors under modulation of the social and physical environment as well as dependent on the premorbid personality. The increased vulnerability which gives rise to this is perceived as a threshold descensus of the individual towards stimuli/irritants (with a deficit counter--irritants impulses). Apart from that, multi-causality of vulnerability is assumed as the starting point, whereby there is the possibility of several therapy approaches. Moreover, contrary to the prevailing pessimistic view that schizophrenia is a process-type progressive disease, an episodic nature of schizophrenic psychoses is postulated with a prognosis that is indeed positive in the long term. In recent years, although often not explicitly stated, Zubin's concept of vulnerability was also indubitably subjected to various further developments (the vulnerability stress model by Nuechterlein and associates as also the integrative psycho-biological schizophrenia model by Ciompi may serve as examples). Worth mentioning are also various new concepts from system sciences (such as those from cybernetics, synergetics, the chaos theory, the communication theory, structure determinism etc.), which endeavour to clarify the problem of psychosis. The evaluation of central neurophysiological function deviations with schizophrenics and their relations has so far been oriented above all towards the vulnerability model of Zubin and Nuechterlein, which differentiates temporarily relatively stable trait markers with generally unaltered expressivity at the pre-, intra-, and post-psychotic stages as well as episode markers and intermediate markers. However, specific factors contributing to the pathogenesis of schizophrenic disturbances have not as yet been found, in addition, there is still a multitude of methodological problems and distinctive features to fulfill the expectation of a comprehensive concept with which the whole complexity of the occurrence, the progress, and the outcome of psychoses can be explained. Reintroduction of the concept of vulnerability experienced, as Schmidt-Degenhardt put it, "a renaissance in use that appeared almost inflationary and a completely dubious popularisation ... without reference to its historical implications...". Consequently, a critical view of the use of this term would appear to be necessary. PMID:11488245

  5. Climate challenges, vulnerabilities, and food security

    PubMed Central

    Nelson, Margaret C.; Ingram, Scott E.; Dugmore, Andrew J.; Streeter, Richard; Peeples, Matthew A.; McGovern, Thomas H.; Hegmon, Michelle; Arneborg, Jette; Brewington, Seth; Spielmann, Katherine A.; Simpson, Ian A.; Strawhacker, Colleen; Comeau, Laura E. L.; Torvinen, Andrea; Madsen, Christian K.; Hambrecht, George; Smiarowski, Konrad

    2016-01-01

    This paper identifies rare climate challenges in the long-term history of seven areas, three in the subpolar North Atlantic Islands and four in the arid-to-semiarid deserts of the US Southwest. For each case, the vulnerability to food shortage before the climate challenge is quantified based on eight variables encompassing both environmental and social domains. These data are used to evaluate the relationship between the “weight” of vulnerability before a climate challenge and the nature of social change and food security following a challenge. The outcome of this work is directly applicable to debates about disaster management policy. PMID:26712017

  6. Assessment of Chemical and Radiological Vulnerabilities

    SciTech Connect

    SETH, S.S.

    2000-05-17

    Following the May 14, 1997 chemical explosion at Hanford's Plutonium Reclamation Facility, the Department of Energy Richland Operations Office and its prime contractor, Fluor Hanford, Inc., completed an extensive assessment to identify and address chemical and radiological safety vulnerabilities at all facilities under the Project Hanford Management Contract. This was a challenging undertaking because of the immense size of the problem, unique technical issues, and competing priorities. This paper focuses on the assessment process, including the criteria and methodology for data collection, evaluation, and risk-based scoring. It does not provide details on the facility-specific results and corrective actions, but discusses the approach taken to address the identified vulnerabilities.

  7. Climate challenges, vulnerabilities, and food security.

    PubMed

    Nelson, Margaret C; Ingram, Scott E; Dugmore, Andrew J; Streeter, Richard; Peeples, Matthew A; McGovern, Thomas H; Hegmon, Michelle; Arneborg, Jette; Kintigh, Keith W; Brewington, Seth; Spielmann, Katherine A; Simpson, Ian A; Strawhacker, Colleen; Comeau, Laura E L; Torvinen, Andrea; Madsen, Christian K; Hambrecht, George; Smiarowski, Konrad

    2016-01-12

    This paper identifies rare climate challenges in the long-term history of seven areas, three in the subpolar North Atlantic Islands and four in the arid-to-semiarid deserts of the US Southwest. For each case, the vulnerability to food shortage before the climate challenge is quantified based on eight variables encompassing both environmental and social domains. These data are used to evaluate the relationship between the "weight" of vulnerability before a climate challenge and the nature of social change and food security following a challenge. The outcome of this work is directly applicable to debates about disaster management policy. PMID:26712017

  8. Targeting the vulnerable: a review of the necessity and feasibility of targeting vulnerable households.

    PubMed

    Jaspars, S; Shoham, J

    1999-12-01

    This article examines whether it is possible to target vulnerable households within a geographically defined area. It looks first at the justification for targeting and then reviews recent practical experience in actually trying to reach vulnerable groups. As complex emergencies increasingly last longer, strategies to target vulnerable households are common in the protracted phase of the emergency. While this is often necessary because of a decline in resources, it is not always justified by an improvement in nutritional status or food security of the beneficiary population. Common target groups are the poor and the malnourished, but in complex emergencies these are not always the most vulnerable. Moreover, recent practical experience has shown considerable difficulties in targeting the poor. Methods to target the poor rely on community-based relief committees, whose priorities are not necessarily the same as those of external agencies. This paper gives examples of such targeted assistance programmes in Kenya, south Sudan and Tanzania. The paper concludes that situations where targeting vulnerable households is justified and feasible are extremely limited. It is suggested that if targeting has to be done because of scarce resources, this should be done on a geographical basis and on the basis of nutritional status. Case-study material shows that it is essential to understand the political determinants of vulnerability and to design methods that will reach the most vulnerable. PMID:10643112

  9. The vulnerability cube: a multi-dimensional framework for assessing relative vulnerability.

    PubMed

    Lin, Brenda B; Morefield, Philip E

    2011-09-01

    The diversity and abundance of information available for vulnerability assessments can present a challenge to decision-makers. Here we propose a framework to aggregate and present socioeconomic and environmental data in a visual vulnerability assessment that will help prioritize management options for communities vulnerable to environmental change. Socioeconomic and environmental data are aggregated into distinct categorical indices across three dimensions and arranged in a cube, so that individual communities can be plotted in a three-dimensional space to assess the type and relative magnitude of the communities' vulnerabilities based on their position in the cube. We present an example assessment using a subset of the USEPA National Estuary Program (NEP) estuaries: coastal communities vulnerable to the effects of environmental change on ecosystem health and water quality. Using three categorical indices created from a pool of publicly available data (socioeconomic index, land use index, estuary condition index), the estuaries were ranked based on their normalized averaged scores and then plotted along the three axes to form a vulnerability cube. The position of each community within the three-dimensional space communicates both the types of vulnerability endemic to each estuary and allows for the clustering of estuaries with like-vulnerabilities to be classified into typologies. The typologies highlight specific vulnerability descriptions that may be helpful in creating specific management strategies. The data used to create the categorical indices are flexible depending on the goals of the decision makers, as different data should be chosen based on availability or importance to the system. Therefore, the analysis can be tailored to specific types of communities, allowing a data rich process to inform decision-making. PMID:21638079

  10. Prediction of vulnerable zones for reactive substances

    SciTech Connect

    Miller, M.K. ); Wong, K.F.V.

    1993-10-01

    Emergency planning committees across the US are preparing emergency response plans for the release of extremely hazardous substances into the atmosphere. These plans include the use of models to predict the atmospheric dispersion of the extremely hazardous substances. The US Environmental Protection Agency has produced a list of extremely hazardous substances and their concentrations where there is immediate danger to life and health, the Technical guidance for Hazards Analysis. An area where the concentration of substance reaches a level detrimental to life is called the vulnerable zone. When a hazardous substance such as fluorine is released into moist air the resulting mixture becomes more toxic due to the interaction of fluorine and water vapor. Data used by the local planning committees to determine the emergency planning levels of the toxic substance usually do not take this reaction into the plume calculations. This paper describes the effect of the vulnerable zone determination for the extremely hazardous substances which can react with the atmospheric environment. This paper determines the vulnerable zones for two reactive substances; in one case the vulnerable zone is misrepresented by 1,700 percent, and in the other case, the substance is not even included as an extremely hazardous substance.

  11. African agriculture especially vulnerable to warming climate

    NASA Astrophysics Data System (ADS)

    Wendel, JoAnna

    2014-09-01

    Malnourishment across Africa could jump 40% by 2050 due to climate change, according to the Africa Agriculture Status Report 2014 (AASR), released on 2 September. With temperatures predicted to rise 1.5°C-2.5°C by midcentury, African smallholder farms, which are generally run by one family, are more vulnerable than ever, the report finds.

  12. Perceived Vulnerability to Disease Predicts Environmental Attitudes

    ERIC Educational Resources Information Center

    Prokop, Pavol; Kubiatko, Milan

    2014-01-01

    Investigating predictors of environmental attitudes may bring valuable benefits in terms of improving public awareness about biodiversity degradation and increased pro-environmental behaviour. Here we used an evolutionary approach to study environmental attitudes based on disease-threat model. We hypothesized that people vulnerable to diseases may…

  13. Cosmopolitan Sensitivities, Vulnerability, and Global Englishes

    ERIC Educational Resources Information Center

    Jacobsen, Ushma Chauhan

    2015-01-01

    This paper is the outcome of an afterthought that assembles connections between three elements: the ambitions of cultivating cosmopolitan sensitivities that circulate vibrantly in connection with the internationalization of higher education, a course on Global Englishes at a Danish university and the sensation of vulnerability. It discusses the…

  14. Retrieval from Memory: Vulnerable or Inviolable?

    ERIC Educational Resources Information Center

    Jones, Dylan M.; Marsh, John E.; Hughes, Robert W.

    2012-01-01

    We show that retrieval from semantic memory is vulnerable even to the mere presence of speech. Irrelevant speech impairs semantic fluency--namely, lexical retrieval cued by a semantic category name--but only if it is meaningful (forward speech compared to reversed speech or words compared to nonwords). Moreover, speech related semantically to the…

  15. Chemical Safety Vulnerability Working Group Report

    SciTech Connect

    Not Available

    1994-09-01

    This report marks the culmination of a 4-month review conducted to identify chemical safety vulnerabilities existing at DOE facilities. This review is an integral part of DOE's efforts to raise its commitment to chemical safety to the same level as that for nuclear safety.

  16. CYBER/PHYSICAL SECURITY VULNERABILITY ASSESSMENT INTEGRATION

    SciTech Connect

    MacDonald, Douglas G.; Key, Brad; Clements, Samuel L.; Hutton, William J.; Craig, Philip A.; Patrick, Scott W.; Crawford, Cary E.

    2011-07-17

    This internally funded Laboratory-Directed R&D project by the Pacific Northwest National Laboratory, in conjunction with QinetiQ North America, is intended to identify and properly assess areas of overlap (and interaction) in the vulnerability assessment process between cyber security and physical protection. Existing vulnerability analysis (VA) processes and software tools exist, and these are heavily utilized in the determination of predicted vulnerability within the physical and cyber security domains. These determinations are normally performed independently of one another, and only interact on a superficial level. Both physical and cyber security subject matter experts have come to realize that though the various interactive elements exist, they are not currently quantified in most periodic security assessments. This endeavor aims to evaluate both physical and cyber VA techniques and provide a strategic approach to integrate the interdependent relationships of each into a single VA capability. This effort will also transform the existing suite of software currently utilized in the physical protection world to more accurately quantify the risk associated with a blended attack scenario. Performance databases will be created to support the characterization of the cyber security elements, and roll them into prototype software tools. This new methodology and software capability will enable analysts to better identify and assess the overall risk during a vulnerability analysis.

  17. Vulnerability--A New View of Schizophrenia

    ERIC Educational Resources Information Center

    Zubin, Joseph; Spring, Bonnie

    1977-01-01

    Although descriptive and etiological approaches to psychopathology have made notable advances, they seem to have reached a plateau. After reviewing the six approaches to etiology that now preempt the field--ecological, developmental, learning, genetic, internal environment, and neurophysiological models--a second-order model, vulnerability, is…

  18. Who's Vulnerable in Infant Child Care Centers?

    ERIC Educational Resources Information Center

    Kendall, Earline D.; Moukaddem, Virginia E.

    1992-01-01

    Maintains that infants and toddlers, parents, and child caregivers are vulnerable to a variety of infectious diseases from infant-toddler child care centers. These diseases include infectious diarrhea; rubella; cytomeglovirus; hepatitis A, and haemophilus influenza type B. Suggests ways to prevent the spread of such diseases. (BB)

  19. A physical approach on flood risk vulnerability

    NASA Astrophysics Data System (ADS)

    Mazzorana, Bruno; Fuchs, Sven; Keiler, Margreth

    2013-04-01

    The design of efficient flood risk mitigation strategies and their subsequent implementation relies on a careful vulnerability analysis of the elements exposed to flood hazard. Recently, extensive research efforts were undertaken to develop and refine empirical relationships linking the structural vulnerability of buildings to the intensity of the impacting water-related hazard processes. These empirical vulnerability functions allow for an estimation of the expected direct losses as a result of the hazard scenario on the basis of a spatially explicit representation of the process patterns and the elements at risk, and improve both risk assessments and cost-benefit analyses of planned mitigation strategies. However, due to the underlying empiricism of such vulnerability functions, the physics of the damage generating mechanisms remain unveiled, and, as such, the applicability of the empirical approach for planning hazard-proof residential buildings is rather limited. Therefore, we propose a conceptual assessment scheme to close this gap. This assessment scheme comprises distinct analytical steps: (a) modelling the process intensity and (b) the impact on the element at risk exposed, (c) the physical response of the building envelope, (d) the damage accounting and (f) the economic damage valuation. This dynamic assessment supports all relevant planning activities with respect to a minimisation of flood hazard losses, and can be implemented in the operational risk assessment procedure.

  20. Criminal injuries compensation: Protecting vulnerable applicants.

    PubMed

    Guthrie, Robert

    2015-09-01

    Each year large numbers of persons sustain injury as a consequence of criminal behaviour. All Australian jurisdictions provide State-funded compensation to those harmed in this way. In the case of vulnerable applicants, the Assessor must consider not simply the appropriate and fair amount of compensation, but also how a person will be affected by the payment of compensation. Often a vulnerable applicant will apply through a guardian or a public trustee, although many apply in person. This article examines the use of legislative provisions, rules, regulations and practices in the various Australian jurisdictions in relation to how vulnerable applicants may be protected and supported once an award of compensation is made in their favour. Most jurisdictions provide for a mechanism by which compensation may be held in trust where the Assessor considers that the applicant may be unable to manage his or her financial affairs in his or her best interests. This article explores what factors are taken into account by Assessors in the absence of and pursuant to legislative directions. It considers how the approach may vary across jurisdictions and creative approaches to financial protection of vulnerable applicants. PMID:26554206

  1. DEMONSTRATING APPLICATIONS OF REGIONAL VULNERABILITY ASSESSMENT

    EPA Science Inventory

    This task is designed to respond to 2 Congressional earmarks of $1,000,000 to the Canaan Valley Institute (CVI) to work in close coordination with the Regional Vulnerability Assessment (ReVA) initiative to develop research and educational tools using integrative technologies to p...

  2. Detecting the vulnerable plaque in patients.

    PubMed

    Gonçalves, I; den Ruijter, H; Nahrendorf, M; Pasterkamp, G

    2015-11-01

    Atherosclerosis is a systemic condition that eventually evolves into vulnerable plaques and cardiovascular events. Pathology studies reveal that rupture-prone atherosclerotic plaques have a distinct morphology, namely a thin, inflamed fibrous cap covering a large lipidic and necrotic core. With the fast development of imaging techniques in the last decades, detecting vulnerable plaques thereby identifying individuals at high risk for cardiovascular events has become of major interest. Yet, in current clinical practice, there is no routine use of any vascular imaging modality to assess plaque characteristics as each unique technique has its pros and cons. This review describes the techniques that may evolve into screening tool for the detection of the vulnerable plaque. Finally, it seems that plaque morphology has been changing in the last decades leading to a higher prevalence of 'stable' atherosclerotic plaques, possibly due to the implementation of primary prevention strategies or other approaches. Therefore, the nomenclature of vulnerable plaque lesions should be very carefully defined in all studies. PMID:26306911

  3. Perceived Vulnerability to Disease Predicts Environmental Attitudes

    ERIC Educational Resources Information Center

    Prokop, Pavol; Kubiatko, Milan

    2014-01-01

    Investigating predictors of environmental attitudes may bring valuable benefits in terms of improving public awareness about biodiversity degradation and increased pro-environmental behaviour. Here we used an evolutionary approach to study environmental attitudes based on disease-threat model. We hypothesized that people vulnerable to diseases may…

  4. Cosmopolitan Sensitivities, Vulnerability, and Global Englishes

    ERIC Educational Resources Information Center

    Jacobsen, Ushma Chauhan

    2015-01-01

    This paper is the outcome of an afterthought that assembles connections between three elements: the ambitions of cultivating cosmopolitan sensitivities that circulate vibrantly in connection with the internationalization of higher education, a course on Global Englishes at a Danish university and the sensation of vulnerability. It discusses the…

  5. Educational and Vocational Exploration in Vulnerable Youth

    ERIC Educational Resources Information Center

    Taylor, Sarah

    2011-01-01

    Though numerous studies indicate that youth and young adults who are involved in one or more social service systems have poor educational and employment outcomes, little is known about the pathways to employment and education in this population. In this qualitative study of educational and employment exploration in vulnerable youth, 11 individuals…

  6. Evaluating Youth Work with Vulnerable Young People.

    ERIC Educational Resources Information Center

    Furlong, Andy; Cartmel, Fred; Powney, Janet; Hall, Stuart

    This report presents the results of an 18-month research project that studied the effectiveness of youth work with vulnerable young people. The research, representing six distinct geographical areas of Scotland characterized by disadvantage, focused on young people aged 13 to 16. In each neighborhood, the project examined the experiences of young…

  7. Seismic vulnerability assessments in risk analysis

    NASA Astrophysics Data System (ADS)

    Frolova, Nina; Larionov, Valery; Bonnin, Jean; Ugarov, Alexander

    2013-04-01

    The assessment of seismic vulnerability is a critical issue within natural and technological risk analysis. In general, there are three common types of methods used for development of vulnerability functions of different elements at risk: empirical, analytical and expert estimations. The paper addresses the empirical methods for seismic vulnerability estimation for residential buildings and industrial facilities. The results of engineering analysis of past earthquake consequences, as well as the statistical data on buildings behavior during strong earthquakes presented in the different seismic intensity scales, are used to verify the regional parameters of mathematical models in order to simulate physical and economic vulnerability for different building types classified according to seismic scale MMSK-86. Verified procedure has been used to estimate the physical and economic vulnerability of buildings and constructions against earthquakes for the Northern Caucasus Federal region of the Russian Federation and Krasnodar area, which are characterized by rather high level of seismic activity and high population density. In order to estimate expected damage states to buildings and constructions in the case of the earthquakes according to the OSR-97B (return period T=1,000 years) within big cities and towns, they were divided into unit sites and their coordinates were presented as dots located in the centers of unit sites. Then the indexes obtained for each unit site were summed up. The maps of physical vulnerability zoning for Northern Caucasus Federal region of the Russian Federation and Krasnodar area includes two elements: percent of different damage states for settlements with number of inhabitants less than 1,000 and vulnerability for cities and towns with number of inhabitants more than 1,000. The hypsometric scale is used to represent both elements on the maps. Taking into account the size of oil pipe line systems located in the highly active seismic zones in the Russian Federation the corresponding procedures have been developed. They are based on mathematical modeling of the system elements' interaction: the oil pipe line and ground, in the case of seismic loads. As a result the dependence-ships between the probability of oil pipe line system to be damaged, and the intensity of shaking in grades of seismic scales have been obtained. The following three damage states for oil pipe line systems have been considered: light damage - elastic deformation of the linear part; localized plastic deformation without breaching the pipeline; average damage - significant plastic deformation of the linear part; fistulas in some areas; complete destruction - large horizontal and vertical displacements of the linear part; mass fistulas, cracks; "guillotine break" of pipe line in some areas.

  8. The specificity of cognitive vulnerabilities to emotional disorders: anxiety sensitivity, looming vulnerability and explanatory style.

    PubMed

    Reardon, John M; Williams, Nathan L

    2007-01-01

    Mood and anxiety disorders share considerable phenomenological and diagnostic overlap. Several models have advanced the understanding of the phenomenological overlap of anxiety and depression; however, identification of disorder-specific etiological mechanisms remains elusive. Recently, research has advanced several cognitive vulnerability-stress models proposing that one's characteristic way of attending to, interpreting, and remembering negative events contributes vulnerability to psychopathology. These cognitive vulnerabilities may elucidate specific etiological mechanisms that distinguish mood and anxiety pathology. The present study examines the specificity of three cognitive vulnerability constructs, the looming cognitive style, anxiety sensitivity, and explanatory style, in the prediction of latent anxiety disorder symptoms and latent depression symptoms. Structural equation modeling analyses indicated that the looming cognitive style demonstrated specificity predicting only anxiety disorder symptoms whereas anxiety sensitivity and a pessimistic explanatory style predicted both anxiety disorder and mood disorder symptoms. Implications for future research are discussed. PMID:17070666

  9. Health sector approach to vulnerability reduction and emergency preparedness.

    PubMed

    Ben Yahmed, S; Koob, P

    1996-01-01

    Vulnerability is increasing year by year. Statistics show that not only are the human and economic costs of emergencies and disasters increasing, but that the cost of relief assistance has increased 10-fold in the last 11 years. Relief assistance alone can lead to increased vulnerability, by reducing development assistance and leading to further social crises The concept of vulnerability consist of two aspects, susceptibility and resilience; vulnerability reduction aims to reduce susceptibility to hazards and increase community resilience to emergencies. Vulnerability reduction involves vulnerability assessment, hazard prevention and mitigation, and emergency preparedness. Vulnerability reduction aims to decrease community susceptibility and increase community resilience, and can focus on emergencies thus preventing many disasters. Vulnerability reduction protects human development, and prepared communities can maintain and improve their level of development. Vulnerability reduction is the responsibility of all, including the health sector, and all sectors at all levels must assist communities to participate in reducing vulnerability. The health sector work in vulnerability reduction requires coordination at all levels within a country. WHO has been assisting in this work at the international, regional and country levels for many years. There is a need for statistical indicators of vulnerability and the harm caused by major emergencies. Data from these indicators will assist in monitoring and evaluating vulnerability reduction, and targeting communities at risk. PMID:9170230

  10. Aircraft vulnerability analysis by modeling and simulation

    NASA Astrophysics Data System (ADS)

    Willers, Cornelius J.; Willers, Maria S.; de Waal, Alta

    2014-10-01

    Infrared missiles pose a significant threat to civilian and military aviation. ManPADS missiles are especially dangerous in the hands of rogue and undisciplined forces. Yet, not all the launched missiles hit their targets; the miss being either attributable to misuse of the weapon or to missile performance restrictions. This paper analyses some of the factors affecting aircraft vulnerability and demonstrates a structured analysis of the risk and aircraft vulnerability problem. The aircraft-missile engagement is a complex series of events, many of which are only partially understood. Aircraft and missile designers focus on the optimal design and performance of their respective systems, often testing only in a limited set of scenarios. Most missiles react to the contrast intensity, but the variability of the background is rarely considered. Finally, the vulnerability of the aircraft depends jointly on the missile's performance and the doctrine governing the missile's launch. These factors are considered in a holistic investigation. The view direction, altitude, time of day, sun position, latitude/longitude and terrain determine the background against which the aircraft is observed. Especially high gradients in sky radiance occur around the sun and on the horizon. This paper considers uncluttered background scenes (uniform terrain and clear sky) and presents examples of background radiance at all view angles across a sphere around the sensor. A detailed geometrical and spatially distributed radiometric model is used to model the aircraft. This model provides the signature at all possible view angles across the sphere around the aircraft. The signature is determined in absolute terms (no background) and in contrast terms (with background). It is shown that the background significantly affects the contrast signature as observed by the missile sensor. A simplified missile model is constructed by defining the thrust and mass profiles, maximum seeker tracking rate, maximum guidance acceleration and seeker sensitivity. For the purpose of this investigation the aircraft is equipped with conventional pyrotechnic decoy flares and the missile has no counter-countermeasure means (security restrictions on open publication). This complete simulation is used to calculate the missile miss distance, when the missile is launched from different locations around the aircraft. The miss distance data is then graphically presented showing miss distance (aircraft vulnerability) as a function of launch direction and range. The aircraft vulnerability graph accounts for aircraft and missile characteristics, but does not account for missile deployment doctrine. A Bayesian network is constructed to fuse the doctrinal rules with the aircraft vulnerability data. The Bayesian network now provides the capability to evaluate the combined risk of missile launch and aircraft vulnerability. It is shown in this paper that it is indeed possible to predict the aircraft vulnerability to missile attack in a comprehensive modelling and a holistic process. By using the appropriate real-world models, this approach is used to evaluate the effectiveness of specific countermeasure techniques against specific missile threats. The use of a Bayesian network provides the means to fuse simulated performance data with more abstract doctrinal rules to provide a realistic assessment of the aircraft vulnerability.

  11. Vendor System Vulnerability Testing Test Plan

    SciTech Connect

    James R. Davidson

    2005-01-01

    The Idaho National Laboratory (INL) prepared this generic test plan to provide clients (vendors, end users, program sponsors, etc.) with a sense of the scope and depth of vulnerability testing performed at the INL’s Supervisory Control and Data Acquisition (SCADA) Test Bed and to serve as an example of such a plan. Although this test plan specifically addresses vulnerability testing of systems applied to the energy sector (electric/power transmission and distribution and oil and gas systems), it is generic enough to be applied to control systems used in other critical infrastructures such as the transportation sector, water/waste water sector, or hazardous chemical production facilities. The SCADA Test Bed is established at the INL as a testing environment to evaluate the security vulnerabilities of SCADA systems, energy management systems (EMS), and distributed control systems. It now supports multiple programs sponsored by the U.S. Department of Energy, the U.S. Department of Homeland Security, other government agencies, and private sector clients. This particular test plan applies to testing conducted on a SCADA/EMS provided by a vendor. Before performing detailed vulnerability testing of a SCADA/EMS, an as delivered baseline examination of the system is conducted, to establish a starting point for all-subsequent testing. The series of baseline tests document factory delivered defaults, system configuration, and potential configuration changes to aid in the development of a security plan for in depth vulnerability testing. The baseline test document is provided to the System Provider,a who evaluates the baseline report and provides recommendations to the system configuration to enhance the security profile of the baseline system. Vulnerability testing is then conducted at the SCADA Test Bed, which provides an in-depth security analysis of the Vendor’s system.b a. The term System Provider replaces the name of the company/organization providing the system being evaluated. This can be the system manufacturer, a system user, or a third party organization such as a government agency. b. The term Vendor (or Vendor’s) System replaces the name of the specific SCADA/EMS being tested.

  12. Empirical Estimates and Observations of 0Day Vulnerabilities

    SciTech Connect

    Miles A. McQueen; Trevor A. McQueen; Wayne F. Boyer; May R. Chaffin

    2009-01-01

    We define a 0Day vulnerability to be any vulnerability, in deployed software, that has been discovered by at least one person but has not yet been publicly announced or patched. These 0Day vulnerabilities are of particular interest when assessing the risk to a system from exploit of vulnerabilities which are not generally known to the public or, most importantly, to the owners of the system. Using the 0Day definition given above, we analyzed the 0Day lifespans of 491 vulnerabilities and conservatively estimated that in the worst year there were on average 2500 0Day vulnerabilities in existence on any given day. Then using a small but intriguing set of 15 0Day vulnerability lifespans representing the time from actual discovery to public disclosure, we made a more aggressive estimate. In this case, we estimated that in the worst year there were, on average, 4500 0Day vulnerabilities in existence on any given day.

  13. On the Library and Information Literacy Education of Vulnerable Groups

    ERIC Educational Resources Information Center

    Zhu, Tian-hui

    2009-01-01

    This paper defines and classifies vulnerable groups, elaborates the necessity of information literacy education of vulnerable groups, analyzes the feasibility for the library to carry out the education, and then discusses specific measures taken by the library to fulfill it.

  14. Psychological Vulnerability to Completed Suicide: A Review of Empirical Studies.

    ERIC Educational Resources Information Center

    Conner, Kenneth R.; Duberstein, Paul R.; Conwell, Yeates; Seidlitz, Larry; Caine, Eric D.

    2001-01-01

    This article reviews empirical literature on psychological vulnerability to completed suicide. Five constructs have been consistently associated with completed suicide: impulsivity/aggression; depression; anxiety; hopelessness; and self-consciousness/social disengagement. Current knowledge of psychological vulnerability could inform social…

  15. Selective Neuronal Vulnerability in Human Prion Diseases

    PubMed Central

    Guentchev, Marin; Wanschitz, Julia; Voigtländer, Till; Flicker, Helga; Budka, Herbert

    1999-01-01

    Human transmissible spongiform encephalopathies (TSEs) or prion diseases are neurodegenerative disorders of infectious, inherited or sporadic origin and include Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scheinker disease (GSS), kuru and fatal familial insomnia (FFI). Clinicopathologic features of FFI differ markedly from other human TSEs. Previous studies demonstrated selective neuronal vulnerability of parvalbumin positive (PV+) GABAergic inhibitory interneurons in sporadic CJD and experimental TSEs. In this report we show uniform severe loss of PV+ neurons also in other TSEs such as GSS, kuru, new variant and familial CJD. In contrast, these neurons are mostly well preserved, or only moderately reduced, in FFI. Only PV+ neurons surrounded by isolectin-B4 positive perineuronal nets were severely affected in TSEs, suggesting a factor residing in this type of extracellular matrix around PV+ neurons as modulator for the selective neuronal vulnerability. PMID:10550300

  16. The Vulnerable Faces of Pathological Gambling

    PubMed Central

    2005-01-01

    Pathological gambling is an emerging psychiatric disorder that has medical, psychiatric, and social consequences. Recently, research has been focusing on identifying which portions of the population are most vulnerable to developing problems related to ongoing gambling. Specific populations of interest have included adolescents, elderly, minorities, those with comorbid psychiatric or substance use disorders, and gender differences. Each group possesses unique biological, psychological, and/or social characteristics that confer a vulnerability to develop pathological gambling behaviors. Being able to recognize those who are at risk to become pathological gamblers is the first step toward developing effective prevention and early intervention programs. This is Part Two of a three-part series on pathological gambling. Part One appeared in the March issue of Psychiatry 2005. PMID:21179650

  17. Module three: vulnerable/special participant populations.

    PubMed

    Lott, Jason P

    2005-03-01

    ABSTRACT This module is designed to sensitise you to the special needs of participants who belong to populations that are more vulnerable than other participant populations. These populations typically include incompetent persons women who may or may not be pregnant, children, prisoners and refugees, impoverished people, and ethnic minorities. These and similar groups deserve special consideration for a number of important ethical and historical reasons, specifically those that surround the potential for exploitation, problems with informed consent, and concerns about respect for participant autonomy. This module introduces modus operandi that are based on national and international research guidelines for dealing with vulnerable/special participant populations, offering contextually-dependent advice and relevant ethical considerations/arguments for and against their involvement in scientific research endeavours. PMID:15748177

  18. Vulnerability, diversity and scarcity: on universal rights.

    PubMed

    Turner, Bryan Stanley; Dumas, Alex

    2013-11-01

    This article makes a contribution to the on-going debates about universalism and cultural relativism from the perspective of sociology. We argue that bioethics has a universal range because it relates to three shared human characteristics,--human vulnerability, institutional precariousness and scarcity of resources. These three components of our argument provide support for a related notion of 'weak foundationalism' that emphasizes the universality and interrelatedness of human experience, rather than their cultural differences. After presenting a theoretical position on vulnerability and human rights, we draw on recent criticism of this approach in order to paint a more nuanced picture. We conclude that the dichotomy between universalism and cultural relativism has some conceptual merit, but it also has obvious limitations when we consider the political economy of health and its impact on social inequality. PMID:23846549

  19. Information systems vulnerability: A systems analysis perspective

    SciTech Connect

    Wyss, G.D.; Daniel, S.L.; Schriner, H.K.; Gaylor, T.R.

    1996-07-01

    Vulnerability analyses for information systems are complicated because the systems are often geographically distributed. Sandia National Laboratories has assembled an interdisciplinary team to explore the applicability of probabilistic logic modeling (PLM) techniques (including vulnerability and vital area analysis) to examine the risks associated with networked information systems. The authors have found that the reliability and failure modes of many network technologies can be effectively assessed using fault trees and other PLM methods. The results of these models are compatible with an expanded set of vital area analysis techniques that can model both physical locations and virtual (logical) locations to identify both categories of vital areas simultaneously. These results can also be used with optimization techniques to direct the analyst toward the most cost-effective security solution.

  20. An Empirical Measure of Computer Security Strength for Vulnerability Remediation

    ERIC Educational Resources Information Center

    Villegas, Rafael

    2010-01-01

    Remediating all vulnerabilities on computer systems in a timely and cost effective manner is difficult given that the window of time between the announcement of a new vulnerability and an automated attack has decreased. Hence, organizations need to prioritize the vulnerability remediation process on their computer systems. The goal of this…

  1. Reconceptualizing Vulnerability in Personal Narrative Writing with Youths

    ERIC Educational Resources Information Center

    Johnson, Elisabeth

    2014-01-01

    Through a student/teacher classroom conflict, the author explores ways adults produce student writers as vulnerable. Drawing on post-structural concepts of adolescence, identity production, interrogation, and vulnerability, the author details how an English teacher invited students to perform vulnerability in personal narratives about issues like…

  2. Supporting Community in Schools: The Relationship of Resilience and Vulnerability.

    ERIC Educational Resources Information Center

    Calderwood, Patricia E.

    This paper examines the role of community in education. It focuses on the relation between vulnerability and resilience and how this dialectic is fundamental to the workings of community. Community without vulnerability is impoverished since it offers no chance to build resilience. However, vulnerabilities may be perceived as flaws that could be…

  3. Reconceptualizing Vulnerability in Personal Narrative Writing with Youths

    ERIC Educational Resources Information Center

    Johnson, Elisabeth

    2014-01-01

    Through a student/teacher classroom conflict, the author explores ways adults produce student writers as vulnerable. Drawing on post-structural concepts of adolescence, identity production, interrogation, and vulnerability, the author details how an English teacher invited students to perform vulnerability in personal narratives about issues like…

  4. An Empirical Measure of Computer Security Strength for Vulnerability Remediation

    ERIC Educational Resources Information Center

    Villegas, Rafael

    2010-01-01

    Remediating all vulnerabilities on computer systems in a timely and cost effective manner is difficult given that the window of time between the announcement of a new vulnerability and an automated attack has decreased. Hence, organizations need to prioritize the vulnerability remediation process on their computer systems. The goal of this…

  5. NASA's Research in Aircraft Vulnerability Mitigation

    NASA Technical Reports Server (NTRS)

    Allen, Cheryl L.

    2005-01-01

    Since its inception in 1958, the National Aeronautics and Space Administration s (NASA) role in civil aeronautics has been to develop high-risk, high-payoff technologies to meet critical national aviation challenges. Following the events of Sept. 11, 2001, NASA recognized that it now shared the responsibility for improving homeland security. The NASA Strategic Plan was modified to include requirements to enable a more secure air transportation system by investing in technologies and collaborating with other agencies, industry, and academia. NASA is conducting research to develop and advance innovative and commercially viable technologies that will reduce the vulnerability of aircraft to threats or hostile actions, and identify and inform users of potential vulnerabilities in a timely manner. Presented in this paper are research plans and preliminary status for mitigating the effects of damage due to direct attacks on civil transport aircraft. The NASA approach to mitigation includes: preventing loss of an aircraft due to a hit from man-portable air defense systems; developing fuel system technologies that prevent or minimize in-flight vulnerability to small arms or other projectiles; providing protection from electromagnetic energy attacks by detecting directed energy threats to aircraft and on/off-board systems; and minimizing the damage due to high-energy attacks (explosions and fire) by developing advanced lightweight, damage-resistant composites and structural concepts. An approach to preventing aircraft from being used as weapons of mass destruction will also be discussed.

  6. Network vulnerability assessment using Bayesian networks

    NASA Astrophysics Data System (ADS)

    Liu, Yu; Man, Hong

    2005-03-01

    While computer vulnerabilities have been continually reported in laundry-list format by most commercial scanners, a comprehensive network vulnerability assessment has been an increasing challenge to security analysts. Researchers have proposed a variety of methods to build attack trees with chains of exploits, based on which post-graph vulnerability analysis can be performed. The most recent approaches attempt to build attack trees by enumerating all potential attack paths, which are space consuming and result in poor scalability. This paper presents an approach to use Bayesian network to model potential attack paths. We call such graph as "Bayesian attack graph". It provides a more compact representation of attack paths than conventional methods. Bayesian inference methods can be conveniently used for probabilistic analysis. In particular, we use the Bucket Elimination algorithm for belief updating, and we use Maximum Probability Explanation algorithm to compute an optimal subset of attack paths relative to prior knowledge on attackers and attack mechanisms. We tested our model on an experimental network. Test results demonstrate the effectiveness of our approach.

  7. Vulnerability assessment using two complementary analysis tools

    SciTech Connect

    Paulus, W.K.

    1993-07-01

    To analyze the vulnerability of nuclear materials to theft or sabotage, Department of Energy facilities have been using, since 1989, a computer program called ASSESS, Analytic System and Software for Evaluation of Safeguards and Security. During the past year Sandia National Laboratories has began using an additional program, SEES, Security Exercise Evaluation Simulation, enhancing the picture of vulnerability beyond what either program achieves alone. ASSESS analyzes all possible paths of attack on a target and, assuming that an attack occurs, ranks them by the probability that a response force of adequate size can interrupt the attack before theft or sabotage is accomplished. A Neutralization module pits, collectively, a security force against the interrupted adversary force in a fire fight and calculates the probability that the adversaries are defeated. SEES examines a single scenario and simulates in detail the interactions among all combatants. Its output includes shots fired between shooter and target, and the hits and kills. Whereas ASSESS gives breadth of analysis, expressed statistically and performed relatively quickly, SEES adds depth of detail, modeling tactical behavior. ASSESS finds scenarios that exploit the greatest weaknesses of a facility. SEES explores these scenarios to demonstrate in detail how various tactics to nullify the attack might work out. Without ASSESS to find the facility weaknesses, it is difficult to focus SEES objectively on scenarios worth analyzing. Without SEES to simulate the details of response vs. adversary interaction, it is not possible to test tactical assumptions and hypotheses. Using both programs together, vulnerability analyses achieve both breadth and depth.

  8. Assessment of Groundwater Vulnerability in Changwon, Korea

    NASA Astrophysics Data System (ADS)

    Lim, J.; Bae, G.; Lee, K.; Suk, H.

    2005-12-01

    In Book-Myeon and Daesan-Myeon in Changwon city, South Korea, riverbank filtration and groundwater pumping plants have been constructed and pumping wells have been operated to extract water from the subsurface. To keep the quality of water that is extracted from those pumping wells to a proper level, contaminant discharge from the background area is needed to be controlled. Knowing the vulnerability of groundwater to contaminants is important for this. The adjoint backward equation of advection dispersion equation is applied in assessing the vulnerability of groundwater. The location and travel time probability of contaminants to a pumping well is derived from the adjoint backward equation. The backward probability model has an advantage that it is physically based on the process of contaminant transport. It can be used to predict the impact of contamination event to a well. With the backward probability model one can have information about the travel time and location of the contaminant discharged at any point in the field site to the pumping well. This method is applied to Book-Myeon and Daesan-Myeon to assess the vulnerability of groundwater from pumping wells to contaminant. From the result of the backward probability model, the information about the location of high risk and the acceptable quantity of contaminant discharge from the background area are given. This information can be useful in setting the better management plan to protect the water quality of the water supply plants.

  9. Vulnerability of Coastal Communities from Storm Surge and Flood Disasters.

    PubMed

    Bathi, Jejal Reddy; Das, Himangshu S

    2016-01-01

    Disasters in the form of coastal storms and hurricanes can be very destructive. Preparing for anticipated effects of such disasters can help reduce the public health and economic burden. Identifying vulnerable population groups can help prioritize resources for the most needed communities. This paper presents a quantitative framework for vulnerability measurement that incorporates both socioeconomic and flood inundation vulnerability. The approach is demonstrated for three coastal communities in Mississippi with census tracts being the study unit. The vulnerability results are illustrated as thematic maps for easy usage by planners and emergency responders to assist in prioritizing their actions to vulnerable populations during storm surge and flood disasters. PMID:26907313

  10. Vulnerability of Coastal Communities from Storm Surge and Flood Disasters

    PubMed Central

    Bathi, Jejal Reddy; Das, Himangshu S.

    2016-01-01

    Disasters in the form of coastal storms and hurricanes can be very destructive. Preparing for anticipated effects of such disasters can help reduce the public health and economic burden. Identifying vulnerable population groups can help prioritize resources for the most needed communities. This paper presents a quantitative framework for vulnerability measurement that incorporates both socioeconomic and flood inundation vulnerability. The approach is demonstrated for three coastal communities in Mississippi with census tracts being the study unit. The vulnerability results are illustrated as thematic maps for easy usage by planners and emergency responders to assist in prioritizing their actions to vulnerable populations during storm surge and flood disasters. PMID:26907313

  11. Not the usual suspects: addressing layers of vulnerability.

    PubMed

    Luna, Florencia; Vanderpoel, Sheryl

    2013-07-01

    This paper challenges the traditional account of vulnerability in healthcare which conceptualizes vulnerability as a list of identifiable subpopulations. This list of 'usual suspects', focusing on groups from lower resource settings, is a narrow account of vulnerability. In this article we argue that in certain circumstances middle-class individuals can be also rendered vulnerable. We propose a relational and layered account of vulnerability and explore this concept using the case study of cord blood (CB) banking. In the first section, two different approaches to 'vulnerability' are contrasted: categorical versus layered. In the second section, we describe CB banking and present a case study of CB banking in Argentina. We examine the types of pressure that middle-class pregnant women feel when considering CB collection and storage. In section three, we use the CB banking case study to critique the categorical approach to vulnerability: this model is unable to account for the ways in which these women are vulnerable. A layered account of vulnerability identifies several ways in which middle-class women are vulnerable. Finally, by utilizing the layered approach, this paper suggests how public health policies could be designed to overcome vulnerabilities. PMID:23718852

  12. Technological solution for vulnerable communities: How does its approach matter?

    NASA Astrophysics Data System (ADS)

    Sianipar, C. P. M.; Dowaki, K.; Yudoko, G.

    2014-06-01

    Vulnerability is an emerging term for both scientific communities and practitioners. Vulnerabilities attributed to a particular community are then aggregated to state it as a vulnerable community. Vulnerability-related study is recognized as an interdisciplinary one due to the complex characteristics of vulnerabilities in each contextual situation. In common understandings, technology is recognized as an interdisciplinary solution, making it possible for supporting any activity in eradicating vulnerability. This study aims to observe such possibilities. Literature survey is taken to investigate the interconnection between vulnerability eradication and technology. Brief comparison between several developing countries and particular focus on Indonesia become a medium of further investigation to reveal issues surrounding technology-related efforts for vulnerability eradication in vulnerable communities. The study reveals that developing countries, particularly Indonesia, tend to adopt approaches from Northern hemisphere, including transferring technologies from developed countries without proper propagation. It means that local knowledge and power are largely ignored in the pursuit of local problem solving for vulnerability eradication. These facts become a signpost to emphasize that approach in implementing technological solution for such purpose is the critical mechanism to ensure the success in every contextual situation. Then, looking at the results of this brief study, its emphasis indicates further requirements to shift the paradigm of typical community development to contextual community empowerment in order to ensure the continuity of every technological solution for a consistent eradication of local vulnerabilities, including possible changes of required approach alongside the shift.

  13. Karst morphology and groundwater vulnerability of high alpine karst plateaus

    NASA Astrophysics Data System (ADS)

    Plan, Lukas; Decker, Kurt; Faber, Robert; Wagreich, Michael; Grasemann, Bernhard

    2009-07-01

    High alpine karst plateaus are recharge areas for major drinking water resources in the Alps and many other regions. Well-established methods for the vulnerability mapping of groundwater to contamination have not been applied to such areas yet. The paper characterises this karst type and shows that two common vulnerability assessment methods (COP and PI) classify most of the areas with high vulnerability classes. In the test site on the Hochschwab plateau (Northern Calcareous Alps, Austria), overlying layers are mostly absent, not protective or even enhance point recharge, where they have aquiclude character. The COP method classifies 82% of the area as highly or extremely vulnerable. The resulting maps are reasonable, but do not differentiate vulnerabilities to the extent that the results can be used for protective measures. An extension for the upper end of the vulnerability scale is presented that allows identifying ultra vulnerable areas. The proposed enhancement of the conventional approach points out that infiltration conditions are of key importance for vulnerability. The method accounts for karst genetical and hydrologic processes using qualitative and quantitative properties of karst depressions and sinking streams including parameters calculated from digital elevations models. The method is tested on the Hochschwab plateau where 1.7% of the area is delineated as ultra vulnerable. This differentiation could not be reached by the COP and PI methods. The resulting vulnerability map highlights spots of maximum vulnerability and the combination with a hazard map enables protective measures for a manageable area and number of sites.

  14. Cultural knowledge and local vulnerability in African American communities

    NASA Astrophysics Data System (ADS)

    Miller Hesed, Christine D.; Paolisso, Michael

    2015-07-01

    Policymakers need to know what factors are most important in determining local vulnerability to facilitate effective adaptation to climate change. Quantitative vulnerability indices are helpful in this endeavour but are limited in their ability to capture subtle yet important aspects of vulnerability such as social networks, knowledge and access to resources. Working with three African American communities on Maryland’s Eastern Shore, we systematically elicit local cultural knowledge on climate change and connect it with a scientific vulnerability framework. The results of this study show that: a given social-ecological factor can substantially differ in the way in which it affects local vulnerability, even among communities with similar demographics and climate-related risks; and social and political isolation inhibits access to sources of adaptive capacity, thereby exacerbating local vulnerability. These results show that employing methods for analysing cultural knowledge can yield new insights to complement those generated by quantitative vulnerability indices.

  15. Assessing flood vulnerability using a rule-based fuzzy system.

    PubMed

    Yazdi, J; Neyshabouri, S A A S

    2012-01-01

    Population growth and urbanization in the last decades have increased the vulnerability of properties and societies in flood-prone areas. Vulnerability analysis is one of the main factors used to determine the necessary measures of flood risk reduction in floodplains. At present, the vulnerability of natural disasters is analyzed by defining the various physical and social indices. This study presents a model based on a fuzzy rule-based system to address various ambiguities and uncertainties from natural variability, and human knowledge and preferences in vulnerability analysis. The proposed method is applied for a small watershed as a case study and the obtained results are compared with one of the index approaches. Both approaches present the same ranking for the sub-basin's vulnerability in the watershed. Finally, using the scores of vulnerability in different sub-basins, a vulnerability map of the watershed is presented. PMID:22907463

  16. Evaluating regional vulnerability to climate change: purposes and methods

    SciTech Connect

    Malone, Elizabeth L.; Engle, Nathan L.

    2011-03-15

    As the emphasis in climate change research, international negotiations, and developing-country activities has shifted from mitigation to adaptation, vulnerability has emerged as a bridge between impacts on one side and the need for adaptive changes on the other. Still, the term vulnerability remains abstract, its meaning changing with the scale, focus, and purpose of each assessment. Understanding regional vulnerability has advanced over the past several decades, with studies using a combination of indicators, case studies and analogues, stakeholder-driven processes, and scenario-building methodologies. As regions become increasingly relevant scales of inquiry for bridging the aggregate and local, for every analysis, it is perhaps most appropriate to ask three “what” questions: “What/who is vulnerable?,” “What is vulnerability?,” and “Vulnerable to what?” The answers to these questions will yield different definitions of vulnerability as well as different methods for assessing it.

  17. HIV vulnerabilities and conflict dynamics. Understanding HIV vulnerabilities in the context of Nepal's conflict.

    PubMed

    Dang, S

    2007-01-01

    The purpose of this research is to understand how Nepal's conflict is affecting vulnerabilities to HIV and exposure to the virus among females and males. Data was primarily collected during a three-week exploratory field study of Surkhet district in 2005. Twenty key informants and 35 stakeholders were interviewed, with the results triangulated by six focus groups. Documentary sources complement this data. A sociological model is designed depicting how the impact of the conflict and the responses of those affected have given rise to three different vulnerabilities to HIV: imposed contextual, conditional contextual and internalised. The paper concludes that the majority of those affected by Nepal's conflict are more vulnerable to the disease and that exposure to the virus may be increasing with forced displacement and migration. PMID:18277532

  18. Systemic vulnerability model for coastal erosion processes

    NASA Astrophysics Data System (ADS)

    Greco, M.; Martino, G.; Guariglia, A.

    2010-09-01

    Many coastal areas constitute an extraordinary environmental worth and economic value resource continuously exposed to an unceasing transformation due to climatic and anthropic factors. The pressure factor overloads carry out an amplification of environmental degradation and economic rent decrease of these territories producing a disruption of normal and anticipated community growth. This paper copes with coastal erosion problem by a systemic vulnerability model application and environmental indicators approach. Through the definition of an original indicator depending on the observed annual rate of coastal erosion and wave climate parameters, such an approach allow scenario generation and it is useful and powerful planning and management tool. The model has been applied on the test case of Ionian Coast of Basilicata Region located in the southern part of Italy, in the middle of Mediterranean basin. The littoral area is constituted of sandy shores of about 50 km length and 5 river deltas take place. Looking at the shoreline in terms of displacements, a shift of a coastal part is a function of grain size characteristics of the shore sands and of the wave climate. Therefore the selected index taking into account the energy stress affecting the shore area, characterizing the territorial system state and finalized to vulnerability estimation, is defined through the maximum annual erosion,tE, and the surface-wave parameters (H,T) corresponding to the wave-generated bottom orbital velocities higher than critical velocity matches with the bottom incipient transport condition. The resulting coefficient ? (? = tE? ? gH2-?T) is obviously dimensionless and represents the part of the available power in the seas, dissipated by erosion processes. If ? increases, the system integrity decreases and the system vulnerability increases. Available data, in terms of topographic/bathymetric information referred to the period 1873-2008, were utilized to derive tE by the use of a GIS-CAD "comb model" developed at the University of Basilicata, in which the full shoreline length was divided in 92 segments corresponding to 500 m for each one. Wave climate data were estimated from wind data by use of a hindcasting method for the observation period 1987-2010. Grain size characteristic of the shore sands were acquired by a in situ measurement campaigns. The ? index gives a synthetic representation of the coastal erosion and progress processes exclusively due to climatic actions and the information derived in terms of vulnerability is distributed on the coastal territory. Results show heterogeneous trends, with relevant difference in vulnerability response among the morphological elements. In particular, the river deltas represent a critical location with significant exposition. By the analyses performed, the southern part of the coast, located near the delta of Sinni river, seems to be more sensible to the vulnerability respect to the other part of the test area.

  19. Earthquakes, vulnerability and disaster risk: Georgia case

    NASA Astrophysics Data System (ADS)

    Tsereteli, Nino; Varazanashvili, Otar; Askan, Aysegul

    2015-04-01

    The Republic of Georgia, located on the East coast of the Black Sea, is prone to multiple natural hazards, the most dangerous and devastating of which are strong earthquakes. This work issues a call for advance planning and action to reduce natural disaster risks, notably seismic risk through the investigation of vulnerability and seismic hazard for Georgia. Ground motion prediction equations are essential for several purposes ranging from seismic design and analysis to probabilistic seismic hazard assessment. Seismic hazard maps were calculated based on modern approach of selecting and ranking global and regional ground motion prediction equation for region. We have also applied the host-to-target method in two regions in Georgia with different source mechanisms. According to the tectonic regime of the target areas, two different regions are chosen as host regions. One of them is the North Anatolian Fault zone in Turkey with the dominant strike-slip source mechanism while the other is Tabas in Iran with mostly events of reverse mechanism. We performed stochastic finite-fault simulations in both host and target areas and employed the hybrid-empirical method as introduced and outlined in Campbell (2003). An initial hybrid empirical ground motion model is developed for PGA and SA at selected periods for Georgia. An application of these coefficients for ground motion models have been used in probabilistic seismic hazard assessment. Intensity based vulnerability study were completed for Georgian buildings. Finally, Probabilistic seismic risk assessment in terms of structural damage and casualties were calculated. This methodology gave prediction of damage and casualty for a given probability of recurrence, based on a probabilistic seismic hazard model, population distribution, inventory, and vulnerability of buildings

  20. Ruptures of vulnerability: Linda Stein's Knight Series.

    PubMed

    Bible, Ann Vollmann

    2010-01-01

    Drawing on the work of Monique Wittig, this article understands Linda Stein's Knight Series as a lacunary writing communicating both her challenges to come to representation and her creative registration of subjectivity. The argument is grounded in an exploration of the rich interplay of power and vulnerability across the series as against the discourse of escapist fashion. Specifically, Stein's critical contradictions of inside and outside, conflated temporality, disjunctions between decoration and abstraction, and fluidity of sex and gender are examined. The discussion is elaborated through consideration of the work of Julia Kristeva, Elizabeth Grosz, and Hayao Miyazaki. PMID:20408009

  1. Children of Darfur: a vulnerable population.

    PubMed

    Chaikin, Jennifer

    2008-02-01

    Four years of intense war in Darfur has created an entire generation of children who might never recover. Children in this region are particularly vulnerable and suffer from issues including physical and psychological illness, malnutrition, rape and unlawful military recruitment. This international crisis is among the most important public health issues in the world. The responsibility of the international community to these children is significant and required to break this cycle. This paper will discuss the concerns surrounding these children, how current strategies are failing and proposed public health nursing interventions. PMID:18190487

  2. Research with protected populations--vulnerable participants.

    PubMed

    Rogers, Bonnie

    2005-04-01

    Workers as study participants are a vulnerable population and additional considerations for their protection in research are needed. Issues related to invasion of privacy and coercion to participate in research studies must be carefully weighed and closely monitored. Worker autonomy must be fostered with respect to assuring that informed consent is given, meaning the information transferred is understood. Research will add to the body of knowledge and advance nursing practice, but one must always remember that risks and benefits must be balanced to achieve appropriate end results. PMID:15853290

  3. Modelling farm vulnerability to flooding: A step toward vulnerability mitigation policies appraisal

    NASA Astrophysics Data System (ADS)

    Brémond, P.; Abrami, G.; Blanc, C.; Grelot, F.

    2009-04-01

    Recent catastrophic flood events such as Elbe in 2002 or Rhône in 2003 have shown limits of flood management policies relying on dykes protection: worsening of flood impacts downstream, increased damage by dykes rupture. Those events, among others, contributes to radical changes on the philosophy of flood prevention, with the promotion of new orientations for mitigating flood exposition. Two new trends may have a significant impact on rural areas: floodplain restoration and vulnerability mitigation. The Rhône River program, which is an contract of objectives signed between French Government and local collectivites, is highly illustrative of these new trends and their impact on agricultural sector. In this program, it appears that areas to be concerned by floodplain restoration are agricultural ones, because their supposed vulnerability to flood is expected to be less important to urban areas. As a consequence, agricultural sector is particularly concerned by planned actions on mitigation of assets vulnerability, an important part of the program (financial support of European Union of 7.5 Million euros). Mitigation of agricultural assets vulnerability reveals particularly interesting for two following reasons. Firstly, it is a way to maintain agricultural activities in floodplains yet existing, without promoting flood protection. Secondly, in case of floodplain restoration, vulnerability mitigation is a way for local authorities to compensate over-flooding impacts. In practice, local authorities may financially support farmers for implementing measures to mitigate their farm vulnerability. On the Rhône River, an important work has already been done to identify farm vulnerability to flooding, and propose measures to mitigate it. More than 3 000 farms exposed to flood risk have been identified representing 88 690 ha of agricultural areas which is estimated to generate damage between 400 and 800 Million euros depending on the season of occurrence for a catastrophic flood. In the case of farm activities, vulnerability mitigation consists in implementing measures which can be: physical (equipment or electric power system elevation), organizational (emergency or recovery plan) or financial (insurance). These measures aim at decreasing the total damage incurred by farmers in case of flooding. For instance, if equipment is elevated, it will not suffer direct damage such as degradation. As a consequence, equipment will be available to continue production or recovery tasks, thus, avoiding indirect damage such as delays, indebtedness… The effects of these policies on farms, in particular vulnerability mitigation cannot be appraised using current methodologies mainly because they do not consider farm as a whole and focus on direct damage at the land plot scale (loss of yield). Moreover, since vulnerability mitigation policies are quite recent, few examples of implementation exist and no feedback experience can be processed. Meanwhile, decision makers and financial actors require more justification of the efficiency of public fund by economic appraisal of the projects. On the Rhône River, decision makers asked for an economic evaluation of the program of farm vulnerability mitigation they plan to implement. This implies to identify the effects of the measures to mitigate farm vulnerability, and to classify them by comparing their efficacy (avoided damage) and their cost of implementation. In this presentation, we propose and discuss a conceptual model of vulnerability at the farm scale. The modelling, in Unified Modelling Language, enabled to represent the ties between spatial, organizational and temporal dimensions, which are central to understanding of farm vulnerability and resilience to flooding. Through this modelling, we encompass three goals: To improve the comprehension of farm vulnerability and create a framework that allow discussion with experts of different disciplines as well as with local farmers; To identify data which are needed to implement the model and to collect them, specifically using the focus group method; Based on the conceptual model, to program a mathematical model which will be used to simulate damage (direct and indirect) on farm due to flood. This last objective should enable us to appraise policy to mitigate vulnerability which is planned to be implemented on Rhône River at the individual and regional scale. Finally, we discuss the possibility to use the UML modelling to develop a multi-agent system approach which could be interesting to take into account ties between farmers (solidarity, loan of equipment) or systemic effects due to the damage incurred by economic partners (loss of market share). Keywords vulnerability, UML modelling, farming systems, flood, mitigation policy, economic valuation

  4. Perspectives on contextual vulnerability in discourses of climate conflict

    NASA Astrophysics Data System (ADS)

    Okpara, U. T.; Stringer, L. C.; Dougill, A. J.

    2016-02-01

    The science of climate security and conflict is replete with controversies. Yet the increasing vulnerability of politically fragile countries to the security consequences of climate change is widely acknowledged. Although climate conflict reflects a continuum of conditional forces that coalesce around the notion of vulnerability, how different portrayals of vulnerability influence the discursive formation of climate conflict relations remains an exceptional but under-researched issue. This paper combines a systematic discourse analysis with a vulnerability interpretation diagnostic tool to explore (i) how discourses of climate conflict are constructed and represented, (ii) how vulnerability is communicated across discourse lines, and (iii) the strength of contextual vulnerability against a deterministic narrative of scarcity-induced conflict, such as that pertaining to land. Systematically characterising climate conflict discourses based on the central issues constructed, assumptions about mechanistic relationships, implicit normative judgements and vulnerability portrayals, provides a useful way of understanding where discourses differ. While discourses show a wide range of opinions "for" and "against" climate conflict relations, engagement with vulnerability has been less pronounced - except for the dominant context centrism discourse concerned about human security (particularly in Africa). In exploring this discourse, we observe an increasing sense of contextual vulnerability that is oriented towards a concern for complexity rather than predictability. The article concludes by illustrating that a turn towards contextual vulnerability thinking will help advance a constructivist theory-informed climate conflict scholarship that recognises historicity, specificity, and variability as crucial elements of contextual totalities of any area affected by climate conflict.

  5. Perspectives on contextual vulnerability in discourses of climate conflict

    NASA Astrophysics Data System (ADS)

    Okpara, U. T.; Stringer, L. C.; Dougill, A. J.

    2015-12-01

    The science of climate security and conflict is replete with controversies. Yet the increasing vulnerability of politically fragile countries to the security consequences of climate change is widely acknowledged. Although climate conflict reflects a continuum of conditional forces that coalesce around the notion of vulnerability, how different portrayals of vulnerability influence the discursive formation of climate conflict relations remains an exceptional but under-researched issue. This paper combines a systematic discourse analysis with a vulnerability interpretation diagnostic tool to explore: (i) how discourses of climate conflict are constructed and represented, (ii) how vulnerability is communicated across discourse lines, and (iii) the strength of contextual vulnerability against a deterministic narrative of scarcity-induced conflict, such as that pertaining to land. Systematically characterising climate conflict discourses based on the central issues constructed, assumptions about mechanistic relationships, implicit normative judgements and vulnerability portrayals, provides a useful way of understanding where discourses differ. While discourses show a wide range of opinions "for" and "against" climate conflict relations, engagement with vulnerability has been less pronounced - except for the dominant context centrism discourse concerned about human security (particularly in Africa). In exploring this discourse, we observe an increasing sense of contextual vulnerability that is oriented towards a concern for complexity rather than predictability. The article concludes by illustrating that a turn towards contextual vulnerability thinking will help advance a constructivist theory-informed climate conflict scholarship that recognises historicity, specificity and variability as crucial elements of contextual totalities of any area affected by climate conflict.

  6. Market mechanisms protect the vulnerable brain

    PubMed Central

    Ramchandran, Kanchna; Nayakankuppam, Dhananjay; Berg, Joyce; Tranel, Daniel

    2011-01-01

    Markets are mechanisms of social exchange, intended to facilitate trading. However, the question remains as to whether markets would help or hurt individuals with decision-makings deficits, as is frequently encountered in the case of cognitive aging. Essential for predicting future gains and losses in monetary and social domains, the striatal nuclei in the brain undergo structural, neurochemical, and functional decline with age. We correlated the efficacy of market mechanisms with dorsal striatal decline in an aging population, by using market based trading in the context of the 2008 U.S Presidential Elections (primary cycle). Impaired decision-makers displayed higher prediction error (difference between their prediction and actual outcome). Lower in vivo caudate volume was also associated with higher prediction error. Importantly, market-based trading protected older adults with lower caudate volume to a greater extent from their own poorly calibrated predictions. Counterintuitive to the traditional public perception of the market as a fickle, risky proposition where vulnerable traders are most surely to be burned, we suggest that market-based mechanisms protect individuals with brain-based decision-making vulnerabilities. PMID:21600226

  7. Evaluating intensity parameters for debris flow vulnerability

    NASA Astrophysics Data System (ADS)

    Keiler, Margreth

    2014-05-01

    In mountain regions natural hazard processes such as debris flows or hyper-concentrated flows repeatedly lead to high damages. After an event, detailed documentation of the meteorological, hydrological and geomorphological indicators are standardized, and additional data on debris covering run out areas, indicators for processes velocity and transported volumes are gathered. Information on deposition height of debris is an important parameter to estimate the intensity of the process impacting the buildings and infrastructure and hence to establish vulnerability curves. However, the deposition height of mobilized material in settlements and on infrastructure is mostly not directly evaluated because recovery work starts immediately or even during the event leading to a removal of accumulated material. Different approaches exist to reconstruct deposition heights after torrent events, such as mind mapping, comparison of LIDAR-based DEM before and after the event as well as the reconstruction by using photo documentation and the estimation of deposition heights according to standardised elements at buildings and infrastructure. In our study, these different approaches to estimate deposition height and the spatial distribution of the accumulated material are applied and compared against each other by using the case study of the debris flow event in Brienz (Switzerland) which occurred during the serve flood events of August 2005 in the Alps. Within the analysis, different factors including overall costs and time consumption (manpower, equipment), accuracy and preciseness are compared and evaluated to establish optimal maps of the extent and deposition depth after torrent events and to integrate this information in the vulnerability analysis.

  8. Reducing societal vulnerability to drought: A methodology

    SciTech Connect

    Wilhite, D.A.

    1995-12-31

    Given worldwide experience with drought during the past several decades and the magnitude of associated impacts, it is apparent that vulnerability to extended periods of water shortage is escalating. Developing a national or provincial drought policy and preparedness plan is a complicated but essential first step toward reducing societal vulnerability. Until recently, nations had devoted little effort to drought preparedness, preferring instead the reactive or crisis management approach. Presently, an increasing number of nations are pursuing a more proactive approach that emphasizes the principles of risk management and sustainable development. Because of the multitude of impacts associated with drought and the numerous governmental agencies that have responsibility for some aspect of monitoring, assessment, mitigation, and planning, developing a policy and plan must be an integrated process within and between levels of government. This paper outlines a generic process that can be adopted by governments that desire to develop a more comprehensive and long-term approach to drought management and planning. Countries and states or provincial authorities that have adopted this approach is presented as case studies. This process is timely, given the declaration of the 1990s as the International Decade for Natural Disaster Reduction and the recent International Convention to Combat Desertification and Drought (June, 1994), an offshoot of deliberations at the United Nations Conference on Environment and Development.

  9. [Neuroethics and Human Vulnerability in Philosophical Perspective].

    PubMed

    Marcos, Alfredo

    2015-01-01

    This article tries to assess the potentials and limits of neuroethics. It argues that neuroscience and ethics should collaborate each other with mutual respect and preservation of their respective identities, scientific in the first case and philosophical in the second one ( neuroethics as cooperation). The text develops also a criticism in front of any attempt to replace the philosophical ethics by the neurosciences ( neuroethics as substitution). Consequently, the most appropriate ontological and anthropological foundations are explored to develop a cooperative neuroethics. These foundations refer to the Aristotelian hylomorphic conception of the substances. On such foundations it is possible to develop a collaborative neuroethics which includes two aspects: on the one hand, we have an ethics of neuroscience and, on the other one, a neuroscience of ethics. The first one shows us how to conduct neuroscience while preserving human dignity. The second one teaches us about the neurobiological basis of our moral agency. These bases enable our moral behavior without determining it. By studying them our vulnerability as moral agents emerges as evidence. This vulnerability, which is rooted in the very human nature, must be, as it is argued along the last pages of the text, recognized as well as mitigated. PMID:26546795

  10. The Mental Vulnerability Questionnaire: a psychometric evaluation.

    PubMed

    Eplov, Lene Falgaard; Petersen, Janne; Jørgensen, Torben; Johansen, Christoffer; Birket-Smith, Morten; Lyngberg, Ann Christine; Mortensen, Erik Lykke

    2010-12-01

    The Mental Vulnerability Questionnaire was originally a 22 item scale, later reduced to a 12 item scale. In population studies the 12 item scale has been a significant predictor of health and illness. The scale has not been psychometrically evaluated for more than 30 years, and the aim of the present study was both to evaluate the psychometric properties of the 22 and 12 item scales and of three new scales. The main study sample was a community sample comprising more than 6,000 men and women. In this sample the coefficients of homogeneity were all over 0.30 for the three new scales, but below 0.30 for the 12 and the 22 item scales. All five Mental Vulnerability scales had positively skewed score distributions which were associated significantly with both SCL-90-R symptom scores and NEO-PI-R personality scales (primarily Neuroticism and Extraversion). Coefficient alpha was highest for the 22 and 12 item scales, and the two scales also showed the highest long-term stability. The three new scales reflect relatively independent dimensions of Psychosomatic Symptoms, Mental Symptoms, and Interpersonal Problems, but because of reliability problems it remains an open question whether they will prove useful as predictors of health and morbidity. PMID:20642738

  11. Market mechanisms protect the vulnerable brain.

    PubMed

    Ramchandran, Kanchna; Nayakankuppam, Dhananjay; Berg, Joyce; Tranel, Daniel; Denburg, Natalie L

    2011-07-01

    Markets are mechanisms of social exchange, intended to facilitate trading. However, the question remains as to whether markets would help or hurt individuals with decision-makings deficits, as is frequently encountered in the case of cognitive aging. Essential for predicting future gains and losses in monetary and social domains, the striatal nuclei in the brain undergo structural, neurochemical, and functional decline with age. We correlated the efficacy of market mechanisms with dorsal striatal decline in an aging population, by using market based trading in the context of the 2008 U.S. Presidential Elections (primary cycle). Impaired decision-makers displayed higher prediction error (difference between their prediction and actual outcome). Lower in vivo caudate volume was also associated with higher prediction error. Importantly, market-based trading protected older adults with lower caudate volume to a greater extent from their own poorly calibrated predictions. Counterintuitive to the traditional public perception of the market as a fickle, risky proposition where vulnerable traders are most surely to be burned, we suggest that market-based mechanisms protect individuals with brain-based decision-making vulnerabilities. PMID:21600226

  12. Vulnerability: the crossroads of frailty and delirium.

    PubMed

    Quinlan, Nicky; Marcantonio, Edward R; Inouye, Sharon K; Gill, Thomas M; Kamholz, Barbara; Rudolph, James L

    2011-11-01

    Frailty and delirium, although seemingly distinct syndromes, both result in significant negative health outcomes in older adults. Frailty and delirium may be different clinical expressions of a shared vulnerability to stress in older adults, and future research will determine whether this vulnerability is age related, pathological, genetic, environmental, or most likely, a combination of all of these factors. This article explores the clinical overlap of frailty and delirium, describes possible pathophysiological mechanisms linking the two, and proposes research opportunities to further knowledge of the interrelationships between these important geriatric syndromes. Frailty, a diminished ability to compensate for stressors, is generally viewed as a chronic condition, whereas delirium is an acute change in attention and cognition, but there is a developing literature on transitions in frailty status around acute events, as well as on delirium as a chronic, persistent condition. If frailty predisposes an individual to delirium, and delirium delays recovery from a stressor, then both syndromes may contribute to a downward spiral of declining function, increasing risk, and negative outcomes. In addition, frailty and delirium may have shared pathophysiology, such as inflammation, atherosclerosis, and chronic nutritional deficiencies, which will require further investigation. The fields of frailty and delirium are rapidly evolving, and future research may help to better define the interrelationship of these common and morbid geriatric syndromes. Because of the heterogeneous pathophysiology and presentation associated with frailty and delirium, typical of all geriatric syndromes, multicomponent prevention and treatment strategies are most likely to be effective and should be developed and tested. PMID:22091571

  13. Evaluating operating system vulnerability to memory errors.

    SciTech Connect

    Ferreira, Kurt Brian; Bridges, Patrick G.; Pedretti, Kevin Thomas Tauke; Mueller, Frank; Fiala, David; Brightwell, Ronald Brian

    2012-05-01

    Reliability is of great concern to the scalability of extreme-scale systems. Of particular concern are soft errors in main memory, which are a leading cause of failures on current systems and are predicted to be the leading cause on future systems. While great effort has gone into designing algorithms and applications that can continue to make progress in the presence of these errors without restarting, the most critical software running on a node, the operating system (OS), is currently left relatively unprotected. OS resiliency is of particular importance because, though this software typically represents a small footprint of a compute node's physical memory, recent studies show more memory errors in this region of memory than the remainder of the system. In this paper, we investigate the soft error vulnerability of two operating systems used in current and future high-performance computing systems: Kitten, the lightweight kernel developed at Sandia National Laboratories, and CLE, a high-performance Linux-based operating system developed by Cray. For each of these platforms, we outline major structures and subsystems that are vulnerable to soft errors and describe methods that could be used to reconstruct damaged state. Our results show the Kitten lightweight operating system may be an easier target to harden against memory errors due to its smaller memory footprint, largely deterministic state, and simpler system structure.

  14. Airport vulnerability assessment: an analytical approach

    NASA Astrophysics Data System (ADS)

    Lazarick, Richard T.

    1998-12-01

    The Airport Vulnerability Assessment Project (AVAP) is the direct result of congressional funding of recommendation 3.13 of the White House Commission on Aviation Safety and Security. This project takes a new approach to the assessment of U.S. commercial airports. AVAP uses automation, analytical methods and tools to evaluate vulnerability and risk, and to analyze cost/benefits in a more quantitative manner. This paper addresses both the process used to conduct this program, as well as a generalized look at the results, which have been achieved for the initial airport assessments. The process description covers the acquisition approach, the project structure, and a review of the various methodologies and tools being used by the sever performing organizations (Abacus Technology, Battelle, CTI, Lockwood Greene, Naval Facilities Engineering Service Center, SAIC, and Science & Engineering Associates). The tools described include ASSESS, SAM, RiskWatch, CASRAP, and AVAT. Included in the process is the utilization of an advisory panel made up predominantly of experts from the National Laboratories 9Sandia, Oak Ridge, Argonne and Brookhaven). The results portion addresses the findings and products resulting from the initial airport assessments. High level (unrestricted) summaries of the results are presented, along with initial trends in commonly recommended security improvements (countermeasures). Opportunities for the application of optics technology are identified.

  15. Vulnerability analysis methods for road networks

    NASA Astrophysics Data System (ADS)

    Bíl, Michal; Vodák, Rostislav; Kube?ek, Jan; Rebok, Tomáš; Svoboda, Tomáš

    2014-05-01

    Road networks rank among the most important lifelines of modern society. They can be damaged by either random or intentional events. Roads are also often affected by natural hazards, the impacts of which are both direct and indirect. Whereas direct impacts (e.g. roads damaged by a landslide or due to flooding) are localized in close proximity to the natural hazard occurrence, the indirect impacts can entail widespread service disabilities and considerable travel delays. The change in flows in the network may affect the population living far from the places originally impacted by the natural disaster. These effects are primarily possible due to the intrinsic nature of this system. The consequences and extent of the indirect costs also depend on the set of road links which were damaged, because the road links differ in terms of their importance. The more robust (interconnected) the road network is, the less time is usually needed to secure the serviceability of an area hit by a disaster. These kinds of networks also demonstrate a higher degree of resilience. Evaluating road network structures is therefore essential in any type of vulnerability and resilience analysis. There are a range of approaches used for evaluation of the vulnerability of a network and for identification of the weakest road links. Only few of them are, however, capable of simulating the impacts of the simultaneous closure of numerous links, which often occurs during a disaster. The primary problem is that in the case of a disaster, which usually has a large regional extent, the road network may remain disconnected. The majority of the commonly used indices use direct computation of the shortest paths or time between OD (origin - destination) pairs and therefore cannot be applied when the network breaks up into two or more components. Since extensive break-ups often occur in cases of major disasters, it is important to study the network vulnerability in these cases as well, so that appropriate steps can be taken in order to make it more resilient. Performing such an analysis of network break-ups requires consideration of the network as a whole, ideally identifying all the cases generated by simultaneous closure of multiple links and evaluating them using various criteria. The spatial distribution of settlements, important companies and the overall population in the nodes of the network are several factors, apart from the topology of the network which could be taken into account when computing vulnerability indices and identifying the weakest links and/or weakest link combinations. However, even for small networks (i.e., hundreds of nodes and links), the problem of break-up identification becomes extremely difficult to resolve. The naive approaches of the brute force examination consequently fail and more elaborated algorithms have to be applied. We address the problem of evaluating the vulnerability of road networks in our work by simulating the impacts of the simultaneous closure of multiple roads/links. We present an ongoing work on a sophisticated algorithm focused on the identification of network break-ups and evaluating them by various criteria.

  16. Vulnerability of housing buildings in Bucharest, Romania

    NASA Astrophysics Data System (ADS)

    Bostenaru, M.

    2009-04-01

    The author participates to the World Housing Encyclopedia project (www.world-housing.net), an internet based database of housing buildings in earthquake prone areas of the world. This is a voluntary project run by the Earthquake Engineering Research Institute, Oakland, California and the International Association of Earthquake Engineering, financial means being available only for the website where the information is shared. For broader dissemination in 2004 a summary publication of the reports to date was published. The database can be querried for various parameters and browsed after geographic distribution. Participation is open to any housing experts. Between 2003 and 2006 the author was also member of the editorial board. The author contributed numerous reports about building types in Romania, and each one about building types in Germany and Switzerland. This presentation will be about the contributed reports on building types in Romania. To the Encyclopedia eight reports on building types from Bucharest were contributed, while in further research of the author one more was similarly described regarding the vulnerability and the seismic retrofit. The selection of these types was done considering the historic development of the built substance in Bucharest from 1850 on, time from which a representative amount of housing buildings which can be classified in typologies can be found in Bucharest. While the structural types are not necessarily characteristic for the style, since the style has other time limits, often appearing before the type became common and then remaining being practiced also after another style gained ground, a historic succession can be seen also in this case. The nine types considered can be grouped in seven time categories: - the time 1850-1880, for a vernacular housing type with masonry load bearing walls and timber floors, - the time 1880-1920, for the type of two storey or multi-storey house with masonry walls and timber floors (in which stylistically the "national style" flourished), - the time 1920-1940 for the type with reinforced concrete skeleton for gravitational loads only (in which the "interwar style" or Romanian Modernism flourished), - the time immediately after 1940 (when a strong earthquake struck Bucharest), somehow 1940-1947, when the former structural type was continued, but with some improvements, for which a type with reinforced concrete diagonals was considered, - the time 1947-1977, before the strong earthquake from 1977, when cast-in-situ reinforced concrete structural wall buildings were spread. Two types are considered, one which displayed low earthquake vulnerability and one which displayed high earthquake vulnerability, - the time 1977-1989, after the strong earthquake from 1977 and before the fall on the communist regime, when taking as a reason the strong earthquake the regime started to implement another type of buildings, which structurally often were still reinforced concrete structural wall type, but prefabricated, - the time after 1989, when for more flexibility moment resisting frame was built, and also some of the unfinished moment resisting frame buildings were completed. To have such a complete description of all the building type in a country is not common for the World Housing Encyclopedia, and having them for Romania was due to a particular effort of the author. At the same time the database allows finding similar types in other parts of the world. Broadly speaking, each report included two sections, the first one more extended, on the vulnerability of buildings and the second on the seismic retrofit. The reports contain completed check lists, descriptions of the structural system, photographs and drawings. The accent in this presentation will be on the identification of seismic deficiencies and earthquake resilient features, and the connected typical damages, which all describe the vulnerability.

  17. Social vulnerability assessment: a growing practice in Europe?

    NASA Astrophysics Data System (ADS)

    Tapsell, S.; McC arthy, S.

    2012-04-01

    This paper builds upon work on social vulnerability from the CapHaz-Net consortium, an ongoing research project funded by the European Commission in its 7th Framework Programme. The project focuses on the social dimensions of natural hazards, as well as on regional practices of risk prevention and management, and aims at improving the resilience of European societies to natural hazards, paying particular attention to social capacity building. The topic of social vulnerability is one of seven themes being addressed in the project. There are various rationales for examining the relevance of social vulnerability to natural hazards. Vulnerability assessment has now been accepted as a requirement for the effective development of emergency management capability, and assessment of social vulnerability has been recognised as being integral to understanding the risk to natural hazards. The aim of our research was to examine social vulnerability, how it might be understood in the context of natural hazards in Europe, and how social vulnerability can be addressed to increase social capacity. The work comprised a review of research on social vulnerability to different natural hazards within Europe and included concepts and definitions of social vulnerability (and related concepts), the purpose of vulnerability assessment and who decides who is vulnerable, different approaches to assessing or measuring social vulnerability (such as the use of 'classical' quantitative vulnerability indicators and qualitative community-based approaches, along with the advantages and disadvantages of both), conceptual frameworks for assessing social vulnerability and three case studies of social vulnerability studies within Europe: flash floods in the Italian Alps, fluvial flooding in Germany and heat waves in Spain. The review reveals variable application of social vulnerability analysis across Europe and there are indications why this might be the case. Reasons could range from the scale of country policy and the particular risk management focus to the smaller scale risk management perceptions of the analysis techniques employed being to resource expensive, difficult to interpret or to operationalise. This paper will provide a context with some empirical examples to perhaps explain the growing popularity of concepts such as resilience and capacity building which lie more comfortably with policy makers and risk managers as concepts which focus on the solution rather than identifying a problem by assessing social vulnerability.

  18. Social vulnerability indicators as a sustainable planning tool

    SciTech Connect

    Lee, Yung-Jaan

    2014-01-15

    In the face of global warming and environmental change, the conventional strategy of resource centralization will not be able to cope with a future of increasingly extreme climate events and related disasters. It may even contribute to inter-regional disparities as a result of these events. To promote sustainable development, this study offers a case study of developmental planning in Chiayi, Taiwan and a review of the relevant literature to propose a framework of social vulnerability indicators at the township level. The proposed framework can not only be used to measure the social vulnerability of individual townships in Chiayi, but also be used to capture the spatial developmental of Chiayi. Seventeen social vulnerability indicators provide information in five dimensions. Owing to limited access to relevant data, the values of only 13 indicators were calculated. By simply summarizing indicators without using weightings and by using zero-mean normalization to standardize the indicators, this study calculates social vulnerability scores for each township. To make social vulnerability indicators more useful, this study performs an overlay analysis of social vulnerability and patterns of risk associated with national disasters. The social vulnerability analysis draws on secondary data for 2012 from Taiwan's National Geographic Information System. The second layer of analysis consists of the flood potential ratings of the Taiwan Water Resources Agency as an index of biophysical vulnerability. The third layer consists of township-level administrative boundaries. Analytical results reveal that four out of the 18 townships in Chiayi not only are vulnerable to large-scale flooding during serious flood events, but also have the highest degree of social vulnerability. Administrative boundaries, on which social vulnerability is based, do not correspond precisely to “cross-administrative boundaries,” which are characteristics of the natural environment. This study adopts an exploratory approach that provides Chiayi and other government agencies with a foundation for sustainable strategic planning for environmental change. The final section offers four suggestions concerning the implications of social vulnerability for local development planning. -- Highlights: • This study proposes a framework of social vulnerability indicators at the township level in Chiayi County, Taiwan. • Seventeen social vulnerability indicators are categorized into four dimensions. • This study performs a three-layer overlay analysis of social vulnerability and natural disaster risk patterns. • 4 out of the 18 townships not only have potential for large-scale flooding, but also high degree of social vulnerability. • This study provides a foundation for sustainable strategic planning to deal with environmental change. • Four suggestions are proposed regarding the implications of social vulnerability for local development planning.

  19. Susceptibility to mountain hazards in Austria - paradigms of vulnerability revisited

    NASA Astrophysics Data System (ADS)

    Fuchs, Sven

    2010-05-01

    The concept of vulnerability is pillared by multiple disciplinary theories underpinning either a technical or a social origin of the concept and resulting in a range of paradigms for either a qualitative or quantitative assessment of vulnerability. However, efforts to reduce susceptibility to hazards and to create disaster-resilient communities require intersections among these theories, since human activity cannot be seen independently from the environmental setting. Acknowledging different roots of disciplinary paradigms, issues determining structural, economic, institutional and social vulnerability are discussed with respect to mountain hazards in Austria. The underlying idea of taking such an integrative viewpoint was the cognition that human action in mountain environments affects the state of vulnerability, and the state of vulnerability in turn shapes the possibilities of human action. It is argued that structural vulnerability as originator results in considerable economic vulnerability, generated by the institutional settings of dealing with natural hazards and shaped by the overall societal framework. Hence, the vulnerability of a specific location and within a considered point of time is triggered by the hazardous event and the related physical susceptibility of structures, such as buildings located on a torrent fan. Depending on the specific institutional settings, economic vulnerability of individuals or of the society results, above all with respect to imperfect loss compensation mechanisms in the areas under investigation. While this potential for harm can be addressed as social vulnerability, the concept of institutional vulnerability has been developed with respect to the overall political settings of governmental risk management. As a result, the concept of vulnerability, as being used in natural sciences, can be extended by integration of possible reasons why such physical susceptibility of structures exists, and by integration of compensation mechanisms and coping strategies being developed within social sciences. If vulnerability and its counterpart, resilience, is analysed and evaluated by using a comprehensive approach, a better understanding of the vulnerability-influencing parameters could be achieved, taking into account the interdependencies and interactions between the disciplinary foci. Thereby the overall aim of this work is not to develop another integrative approach for vulnerability assessment, different approaches are rather applied by using a vulnerability-of-place criterion, and key issues of vulnerability are reconsidered aiming at a general illustration of the situation in a densely populated mountain region of Europe.

  20. Childhood physical abuse and aggression: Shame and narcissistic vulnerability.

    PubMed

    Keene, Amanda C; Epps, James

    2016-01-01

    This study examined narcissistic vulnerability and shame-proneness as potential mediators between childhood physical abuse (CPA) and adult anger and aggression. Participants were 400 undergraduate students, 134 of whom had a history of CPA. All participants completed self-report questionnaires assessing history of CPA, shame-proneness, narcissistic vulnerability, physical aggression, trait anger, and hostility. Results indicated abused participants were more angry and aggressive and experienced higher levels of shame-proneness and narcissistic vulnerability than nonabused participants. Multiple mediation analyses showed that narcissistic vulnerability, but not shame-proneness, partially mediated the relation between abuse and physical aggression. However, narcissistic vulnerability and shame-proneness both emerged as partial mediators between abuse and the anger and hostility variables. These findings suggest that narcissistic vulnerability and shame-proneness may function as mediators of adjustment following childhood maltreatment. Study limitations and recommendations for future research are discussed. PMID:26560235

  1. Cyber Security Vulnerability Impact on I&C Reliability

    SciTech Connect

    Hadley, Mark D.; McBride, Justin B.

    2006-11-01

    We present a discussion of the cyber security vulnerability impact on instrument and control reliability. In the discussion we demonstrate the likely vector of attack and vulnerabilities associated with commodity hardware, protocols and communication media. The current fleet of nuclear power plants in the United States utilizes aging analog instrument and control systems which are more frequently suffering from obsolescence and failure. The commodity equipment available now and in the near future incorporates features from information technology systems which compound cyber vulnerabilities.

  2. Intravascular probe for detection of vulnerable plaque

    NASA Astrophysics Data System (ADS)

    Patt, Bradley E.; Iwanczyk, Jan S.; MacDonald, Lawrence R.; Yamaguchi, Yuko; Tull, Carolyn R.; Janecek, Martin; Hoffman, Edward J.; Strauss, H. William; Tsugita, Ross; Ghazarossian, Vartan

    2001-12-01

    Coronary angiography is unable to define the status of the atheroma, and only measures the luminal dimensions of the blood vessel, without providing information about plaque content. Up to 70% of heart attacks are caused by minimally obstructive vulnerable plaques, which are too small to be detected adequately by angiography. We have developed an intravascular imaging detector to identify vulnerable coronary artery plaques. The detector works by sensing beta or conversion electron radiotracer emissions from plaque-binding radiotracers. The device overcomes the technical constraints of size, sensitivity and conformance to the intravascular environment. The detector at the distal end of the catheter uses six 7mm long by 0.5mm diameter scintillation fibers coupled to 1.5m long plastic fibers. The fibers are offset from each other longitudinally by 6mm and arranged spirally around a guide wire in the catheter. At the proximal end of the catheter the optical fibers are coupled to an interface box with a snap on connector. The interface box contains a position sensitive photomultiplier tube (PSPMT) to decode the individual fibers. The whole detector assembly fits into an 8-French (2.7 mm in diameter) catheter. The PSPMT image is further decoded with software to give a linear image, the total instantaneous count rate and an audio output whose tone corresponds to the count rate. The device was tested with F-18 and Tl-204 sources. Spectrometric response, spatial resolution, sensitivity and beta to background ratio were measured. System resolution is 6 mm and the sensitivity is >500 cps / micrometers Ci when the source is 1 mm from the detector. The beta to background ratio was 11.2 for F-18 measured on a single fiber. The current device will lead to a system allowing imaging of labeled vulnerable plaque in coronary arteries. This type of signature is expected to enable targeted and cost effective therapies to prevent acute coronary artery diseases such as: unstable angina, acute myocardial infarction, and sudden cardiac death.

  3. Assessing Vulnerability to Drought on a pan-European scale

    NASA Astrophysics Data System (ADS)

    Urquijo, Julia; De Stefano, Lucia; González-Tánago, Itziar; Blauhut, Veit; Stahl, Kerstin

    2014-05-01

    During the past decade, a number of theoretical frameworks have been defined within the Disaster Risk Reduction and Climate Change communities to assess drought vulnerability at different scales, sectors, socio-political contexts, and geo-climatic conditions. However, there is still little consensus around the criteria, dimensions and factors used in these assessments; and none of them has been applied at a pan-European scale. This is due to a triple complexity. Firstly, drought as a natural hazard is a complex phenomenon due to the difficulty of determining its onset and its multiscale, multifaceted and dynamic nature. Secondly, there is an on-going debate regarding the concept of vulnerability and its constitutive elements, together with an important diversity of theoretical approaches to assess it. Finally, Europe's diversity in bioclimatic conditions, national water use practice and water use policies adds a challenging characteristic for working on pan-European scale. This work addresses the challenge of defining a methodological approach to the assessment of vulnerability factors to drought at a pan-European scale. For this purpose, we first review existing conceptual frameworks as well as of past initiatives for drought vulnerability assessment. The literature review showed that the high complexity of drought vulnerability assessment requires a clear definition of the concept of vulnerability and the associated terms, and that, before undertaking any assessment, it is necessary to clearly define the "vulnerable unit" i.e. replying to the questions 'whose vulnerability is being assessed?' and 'vulnerability to what type of impact?'. In this context, this work proposes the application of a factor-based approach, consisting in the analysis of significant factors that influence vulnerability in the context of specific situations of potential vulnerability. Those situations are framed within the specific drought characteristics of four different geoclimatic macro -regions in Europe (Southern Europe; Central Europe; Eastern Europe; Northern Europe), to allow for comparison among similar vulnerability units within each region. These 'situations' are proposed as a suitable way to delimit vulnerability conditions, as they make explicit under which assumptions are we operating when undertaking the assessment. Vulnerability factors were determined based on literature review and expert-based validation while the vulnerability situations were derived from a database of registered drought impacts by sectors (European Drought Impact Report Inventory, EDII). The resulting picture is both informative and diagnostic: it provides guidance for the identification of areas and sectors where drought impact needs to be mitigated, and allows for the identification of issues (e.g. adaptive capacity features) that should be addressed to achieve that mitigation of drought impact. The approach is being tested for drought vulnerability assessment on a pan-European scale.

  4. Empirical Estimates of 0Day Vulnerabilities in Control Systems

    SciTech Connect

    Miles A. McQueen; Wayne F. Boyer; Sean M. McBride; Trevor A. McQueen

    2009-01-01

    We define a 0Day vulnerability to be any vulnerability, in deployed software, which has been discovered by at least one person but has not yet been publicly announced or patched. These 0Day vulnerabilities are of particular interest when assessing the risk to well managed control systems which have already effectively mitigated the publicly known vulnerabilities. In these well managed systems the risk contribution from 0Days will have proportionally increased. To aid understanding of how great a risk 0Days may pose to control systems, an estimate of how many are in existence is needed. Consequently, using the 0Day definition given above, we developed and applied a method for estimating how many 0Day vulnerabilities are in existence on any given day. The estimate is made by: empirically characterizing the distribution of the lifespans, measured in days, of 0Day vulnerabilities; determining the number of vulnerabilities publicly announced each day; and applying a novel method for estimating the number of 0Day vulnerabilities in existence on any given day using the number of vulnerabilities publicly announced each day and the previously derived distribution of 0Day lifespans. The method was first applied to a general set of software applications by analyzing the 0Day lifespans of 491 software vulnerabilities and using the daily rate of vulnerability announcements in the National Vulnerability Database. This led to a conservative estimate that in the worst year there were, on average, 2500 0Day software related vulnerabilities in existence on any given day. Using a smaller but intriguing set of 15 0Day software vulnerability lifespans representing the actual time from discovery to public disclosure, we then made a more aggressive estimate. In this case, we estimated that in the worst year there were, on average, 4500 0Day software vulnerabilities in existence on any given day. We then proceeded to identify the subset of software applications likely to be used in some control systems, analyzed the associated subset of vulnerabilities, and characterized their lifespans. Using the previously developed method of analysis, we very conservatively estimated 250 control system related 0Day vulnerabilities in existence on any given day. While reasonable, this first order estimate for control systems is probably far more conservative than those made for general software systems since the estimate did not include vulnerabilities unique to control system specific components. These control system specific vulnerabilities were unable to be included in the estimate for a variety of reasons with the most problematic being that the public announcement of unique control system vulnerabilities is very sparse. Consequently, with the intent to improve the above 0Day estimate for control systems, we first identified the additional, unique to control systems, vulnerability estimation constraints and then investigated new mechanisms which may be useful for estimating the number of unique 0Day software vulnerabilities found in control system components. We proceeded to identify a number of new mechanisms and approaches for estimating and incorporating control system specific vulnerabilities into an improved 0Day estimation method. These new mechanisms and approaches appear promising and will be more rigorously evaluated during the course of the next year.

  5. An integrated approach to vulnerability assessment.

    SciTech Connect

    Tidwell, Vincent Carroll; Jurado, Sariah Ruth; Silva, Consuelo Juanita

    2005-03-01

    How might the quality of a city's delivered water be compromised through natural or malevolent causes? What are the consequences of a contamination event? What water utility assets are at greatest risk to compromise? Utility managers have been scrambling to find answers to these questions since the events of 9/11. However, even before this date utility mangers were concerned with the potential for system contamination through natural or accidental causes. Unfortunately, an integrated tool for assessing both the threat of attack/failure and the subsequent consequence is lacking. To help with this problem we combine Markov Latent Effects modeling for performing threat assessment calculations with the widely used pipe hydraulics/transport code, EPANET, for consequences analysis. Together information from these models defines the risk posed to the public due to natural or malevolent contamination of a water utility system. Here, this risk assessment framework is introduced and demonstrated within the context of vulnerability assessment for water distribution systems.

  6. Costs of strikes between vulnerable missile forces

    SciTech Connect

    Canavan, G.H.

    1997-02-01

    This note derives the first and second strike magnitudes and costs for strikes between vulnerable missile forces with multiple warheads. The extension to mixes with invulnerable missiles is performed in a companion note. Stability increases as the number of weapons per missile is reduced. The optimal allocation of weapons between missiles and value is significant in predicting the stability impact of the reduction of the number of weapons per missile at large numbers of missiles, less significant in reducing the number of missiles for fixed weapons per missile. At low numbers of missiles, the stability indices for singlet and triplet configurations are comparable, as are the number of weapons each would deliver on value targets.

  7. The Vulnerable Indian One Rupee Coin.

    PubMed

    Krishnamurthy, Arvind; Ramshankar, Vijayalakshmi

    2013-01-01

    Coins are the most commonly ingested foreign body encountered in the pediatric population, with a peak incidence between 6 months and 3 years of age. Although some ingested coins may be aspirated, most coins pass through the alimentary tract without causing any complications. Coins in the esophagus causing symptoms require immediate removal. The management of asymptomatic coins has been a perplexing problem to the clinicians for decades. We recently managed an interesting case of an impacted Indian one rupee coin in the esophagus of a 13-year-old girl, by performing a simple yet novel technique, by using a conventional flexible endoscopic biopsy forceps. Further, reviewing the literature we inferred that the rounded, stainless steel Indian one rupee coin with a diameter of 25 mm, by itself seems to be vulnerable for impaction in the esophagus and therefore needs to be promptly addressed even if asymptomatic. PMID:26664846

  8. Method and tool for network vulnerability analysis

    DOEpatents

    Swiler, Laura Painton; Phillips, Cynthia A.

    2006-03-14

    A computer system analysis tool and method that will allow for qualitative and quantitative assessment of security attributes and vulnerabilities in systems including computer networks. The invention is based on generation of attack graphs wherein each node represents a possible attack state and each edge represents a change in state caused by a single action taken by an attacker or unwitting assistant. Edges are weighted using metrics such as attacker effort, likelihood of attack success, or time to succeed. Generation of an attack graph is accomplished by matching information about attack requirements (specified in "attack templates") to information about computer system configuration (contained in a configuration file that can be updated to reflect system changes occurring during the course of an attack) and assumed attacker capabilities (reflected in "attacker profiles"). High risk attack paths, which correspond to those considered suited to application of attack countermeasures given limited resources for applying countermeasures, are identified by finding "epsilon optimal paths."

  9. MODELING UNDERGROUND STRUCTURE VULNERABILITY IN JOINTED ROCK

    SciTech Connect

    R. SWIFT; D. STEEDMAN

    2001-02-01

    The vulnerability of underground structures and openings in deep jointed rock to ground shock attack is of chief concern to military planning and security. Damage and/or loss of stability to a structure in jointed rock, often manifested as brittle failure and accompanied with block movement, can depend significantly on jointed properties, such as spacing, orientation, strength, and block character. We apply a hybrid Discrete Element Method combined with the Smooth Particle Hydrodynamics approach to simulate the MIGHTY NORTH event, a definitive high-explosive test performed on an aluminum lined cylindrical opening in jointed Salem limestone. Representing limestone with discrete elements having elastic-equivalence and explicit brittle tensile behavior and the liner as an elastic-plastic continuum provides good agreement with the experiment and damage obtained with finite-element simulations. Extending the approach to parameter variations shows damage is substantially altered by differences in joint geometry and liner properties.

  10. Protection of vulnerable adults: an interdisciplinary workshop.

    PubMed

    Day, Mary Rose; Bantry-White, Eleanor; Glavin, Pauline

    2010-09-01

    This paper reports on the development, delivery, content and student evaluation of a comprehensive elder abuse and self-neglect workshop for public health nursing and social work students.The workshop provided an interdisciplinary shared learning experience for the students to prepare them for their critical role in safeguarding vulnerable adults. The aim of the workshop was to increase knowledge, awareness and understanding of roles and responsibilities and critical practice problems in the prevention and management of elder abuse and self-neglect. The shared learning approach provided clarity on roles and responsibility, valuing and respecting the contribution of each team member. The importance of building communication and trust with team members and clients was seen as critical. Through case studies and group discussion, assessment and practice skills were developed and awareness heightened on the complexity of the critical practice problems and ethical issues. PMID:20879664

  11. Ecosystems Vulnerability Challenge and Prize Competition

    NASA Astrophysics Data System (ADS)

    Smith, J. H.; Frame, M. T.; Ferriter, O.; Recker, J.

    2014-12-01

    Stimulating innovation and private sector entrepreneurship is an important way to advance the preparedness of communities, businesses and individuals for the impacts of climate change on certain aspects of ecosystems, such as: fire regimes; water availability; carbon sequestration; biodiversity conservation; weather-related hazards, and the spread of invasive species. The creation of tools is critical to help communities and natural resource managers better understand the impacts of climate change on ecosystems and the potential resulting implications for ecosystem services and conservation efforts. The Department of the Interior is leading an interagency effort to develop the Ecosystems Vulnerability theme as part of the President's Climate Action Plan. This effort will provide seamless access to relevant datasets that can help address such issues as: risk of wildfires to local communities and federal lands; water sensitivity to climate change; and understanding the role of ecosystems in a changing climate. This session will provide an overview of the proposed Ecosystem Vulnerability Challenge and Prize Competition, outlining the intended audience, scope, goals, and overall timeline. The session will provide an opportunity for participants to offer new ideas. Through the Challenge, access will be made available to critical datasets for software developers, engineers, scientists, students, and researchers to develop and submit applications addressing critical science issues facing our Nation today. Application submission criteria and guidelines will also be discussed. The Challenge will be open to all sectors and organizations (i.e. federal, non-federal, private sector, non-profits, and universities) within the United States. It is anticipated the Challenge will run from early January 2015 until spring of 2015.

  12. Social Vulnerability and Ebola Virus Disease in Rural Liberia

    PubMed Central

    2015-01-01

    The Ebola virus disease (EVD) epidemic that has stricken thousands of people in the three West African countries of Liberia, Sierra Leone, and Guinea highlights the lack of adaptive capacity in post-conflict countries. The scarcity of health services in particular renders these populations vulnerable to multiple interacting stressors including food insecurity, climate change, and the cascading effects of disease epidemics such as EVD. However, the spatial distribution of vulnerable rural populations and the individual stressors contributing to their vulnerability are unknown. We developed a Social Vulnerability Classification using census indicators and mapped it at the district scale for Liberia. According to the Classification, we estimate that districts having the highest social vulnerability lie in the north and west of Liberia in Lofa, Bong, Grand Cape Mount, and Bomi Counties. Three of these counties together with the capital Monrovia and surrounding Montserrado and Margibi counties experienced the highest levels of EVD infections in Liberia. Vulnerability has multiple dimensions and a classification developed from multiple variables provides a more holistic view of vulnerability than single indicators such as food insecurity or scarcity of health care facilities. Few rural Liberians are food secure and many cannot reach a medical clinic in <80 minutes. Our results illustrate how census and household survey data, when displayed spatially at a sub-county level, may help highlight the location of the most vulnerable households and populations. Our results can be used to identify vulnerability hotspots where development strategies and allocation of resources to address the underlying causes of vulnerability in Liberia may be warranted. We demonstrate how social vulnerability index approaches can be applied in the context of disease outbreaks, and our methods are relevant elsewhere. PMID:26325519

  13. Modeling groundwater vulnerability to pollution using Optimized DRASTIC model

    NASA Astrophysics Data System (ADS)

    Mogaji, Kehinde Anthony; San Lim, Hwee; Abdullar, Khiruddin

    2014-06-01

    The prediction accuracy of the conventional DRASTIC model (CDM) algorithm for groundwater vulnerability assessment is severely limited by the inherent subjectivity and uncertainty in the integration of data obtained from various sources. This study attempts to overcome these problems by exploring the potential of the analytic hierarchy process (AHP) technique as a decision support model to optimize the CDM algorithm. The AHP technique was utilized to compute the normalized weights for the seven parameters of the CDM to generate an optimized DRASTIC model (ODM) algorithm. The DRASTIC parameters integrated with the ODM algorithm predicted which among the study areas is more likely to become contaminated as a result of activities at or near the land surface potential. Five vulnerability zones, namely: no vulnerable(NV), very low vulnerable (VLV), low vulnerable (LV), moderate vulnerable (MV) and high vulnerable (HV) were identified based on the vulnerability index values estimated with the ODM algorithm. Results show that more than 50% of the area belongs to both moderate and high vulnerable zones on the account of the spatial analysis of the produced ODM-based groundwater vulnerability prediction map (GVPM).The prediction accuracy of the ODM-based - GVPM with the groundwater pH and manganese (Mn) concentrations established correlation factors (CRs) result of 90 % and 86 % compared to the CRs result of 62 % and 50 % obtained for the validation accuracy of the CDM - based GVPM. The comparative results, indicated that the ODM-based produced GVPM is more reliable than the CDM - based produced GVPM in the study area. The study established the efficacy of AHP as a spatial decision support technique in enhancing environmental decision making with particular reference to future groundwater vulnerability assessment.

  14. 7 CFR 1730.27 - Vulnerability and Risk Assessment (VRA).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 11 2013-01-01 2013-01-01 false Vulnerability and Risk Assessment (VRA). 1730.27 Section 1730.27 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES... Requirements § 1730.27 Vulnerability and Risk Assessment (VRA). (a) Each borrower with an approved RUS...

  15. 7 CFR 1730.27 - Vulnerability and Risk Assessment (VRA).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 11 2012-01-01 2012-01-01 false Vulnerability and Risk Assessment (VRA). 1730.27 Section 1730.27 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES... Requirements § 1730.27 Vulnerability and Risk Assessment (VRA). (a) Each borrower with an approved RUS...

  16. 7 CFR 1730.27 - Vulnerability and Risk Assessment (VRA).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 11 2014-01-01 2014-01-01 false Vulnerability and Risk Assessment (VRA). 1730.27 Section 1730.27 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES... Requirements § 1730.27 Vulnerability and Risk Assessment (VRA). (a) Each borrower with an approved RUS...

  17. 7 CFR 1730.27 - Vulnerability and Risk Assessment (VRA).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Vulnerability and Risk Assessment (VRA). 1730.27 Section 1730.27 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES... Requirements § 1730.27 Vulnerability and Risk Assessment (VRA). (a) Each borrower with an approved RUS...

  18. 7 CFR 1730.27 - Vulnerability and Risk Assessment (VRA).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 11 2011-01-01 2011-01-01 false Vulnerability and Risk Assessment (VRA). 1730.27 Section 1730.27 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES... Requirements § 1730.27 Vulnerability and Risk Assessment (VRA). (a) Each borrower with an approved RUS...

  19. Social Vulnerability Scale for Older Adults: Validation Study

    ERIC Educational Resources Information Center

    Pinsker, Donna M.; Stone, Valerie; Pachana, Nancy; Greenspan, Stephen

    2006-01-01

    The Social Vulnerability Scale (SVS), an informant-report of social vulnerability for older adults, was piloted in a sample of 167 undergraduate students (63 male, 104 female) from the University of Queensland. Participants aged 18 - 53 (M = 25.53 years, SD = 7.83 years) completed the SVS by rating a relative or friend aged [greater than or equal…

  20. International Space Station: Meteoroid/Orbital Debris Survivability and Vulnerability

    NASA Technical Reports Server (NTRS)

    Graves, Russell

    2000-01-01

    This slide presentation reviews the surviability and vulnerability of the International Space Station (ISS) from the threat posed by meteoroid and orbital debris. The topics include: (1) Space station natural and induced environments (2) Meteoroid and orbital debris threat definition (3) Requirement definition (4) Assessment methods (5) Shield development and (6) Component vulnerability

  1. A framework for understanding old-age vulnerabilities

    PubMed Central

    SCHRÖDER-BUTTERFILL, ELISABETH; MARIANTI, RULY

    2007-01-01

    Identifying vulnerable older people and understanding the causes and consequences of their vulnerability is of human concern and an essential task of social policy. To date, vulnerability in old age has mainly been approached by identifying high risk groups, like the poor, childless, frail or isolated. Yet vulnerability is the outcome of complex interactions of discrete risks, namely of being exposed to a threat, of a threat materialising, and of lacking the defences or resources to deal with a threat. In this article, we review approaches to vulnerability in various disciplines in order to develop a systematic framework for approaching vulnerability. This framework distinguishes and examines the interactions among the domains of exposure, threats, coping capacities and outcomes. Drawing on European and Asian gerontological literature, we discuss what might be meant by these domains and their place in the understanding of vulnerability in old age. Two case studies are presented - one on homelessness in Britain, the other on familial care provision in Indonesia - to illustrate the ways in which specific vulnerabilities are created and distributed over the lifecourse. PMID:23750062

  2. A quantitative vulnerability function for fluvial sediment transport

    NASA Astrophysics Data System (ADS)

    Totschnig, Reinhold; Sedlacek, Walter; Fuchs, Sven

    2010-05-01

    In quantitative risk assessment, risk is expressed as a function of hazard, elements at risk exposed, and the vulnerability. From a natural sciences perspective, vulnerability is defined as the expected degree of loss for an element at risk as a consequence of a certain event. The resulting value is dependent on the impacting process intensity and the susceptibility of the elements at risk, and ranges from 0 (no damage) to 1 (complete destruction). With respect to torrent processes, i.e. fluvial sediment transport, the concept of vulnerability - though widely acknowledged - did not result in any sound quantitative relationship between process intensities and vulnerability values so far, even if considerable loss occurred during recent years. To close this gap and establish this relationship, data from three well-documented torrent events in the Austrian Alps was used to derive a quantitative vulnerability function applicable to residential buildings located on torrent fans. The method applied followed a spatial approach, and was based on process intensities, the spatial characteristics of elements at risk, and average reconstruction values on a local scale. The results suggest a modified Weibull function to fit best to the observed damage pattern if vulnerability is quantified in absolute values, and a modified Frechet function if vulnerability is quantified relatively in relation to the individual building height. The vulnerability relationship obtained is applicable to a mixed type of construction used in European mountain regions, composed from brick masonry and concrete, a typical design in post-1950s building craft in alpine countries.

  3. Assessing local vulnerability to climate change in Ecuador.

    PubMed

    Fernandez, Mario Andres; Bucaram, Santiago J; Renteria, Willington

    2015-01-01

    Vulnerability assessments have become necessary to increase the understanding of climate-sensitive systems and inform resource allocation in developing countries. Challenges arise when poor economic and social development combines with heterogeneous climatic conditions. Thus, finding and harmonizing good-quality data at local scale may be a significant hurdle for vulnerability research. In this paper we assess vulnerability to climate change at a local level in Ecuador. We take Ecuador as a case study as socioeconomic data are readily available. To incorporate the spatial and temporal pattern of the climatic variables we use reanalysis datasets and empirical orthogonal functions. Our assessment strategy relies on the statistical behavior of climatic and socioeconomic indicators for the weighting and aggregation mechanism into a composite vulnerability indicator. Rather than assuming equal contribution to the formation of the composite indicator, we assume that the weights of the indicators vary inversely as the variance over the cantons (administrative division of Ecuador). This approach captures the multi-dimensionality of vulnerability in a comprehensive form. We find that the least vulnerable cantons concentrate around Ecuador's largest cities (e.g. Quito and Guayaquil); however, approximately 20 % of the national population lives in other cantons that are categorized as highly and very highly vulnerable to climate change. Results also show that the main determinants of high vulnerability are the lack of land tenure in agricultural areas and the nonexistence of government-funded programs directed to environmental and climate change management. PMID:26640750

  4. Development and Demography of Perceived Vulnerability in Youngsters.

    ERIC Educational Resources Information Center

    Gochman, David S.

    In order to assess children's perceived vulnerability to health problems, a longitudinal study was designed to observe third and seventh graders at five intervals over a 2-year period. The hypotheses tested concerned relationships between perceived vulnerability to health problems and age, sex, and socioeconomic status. Data were obtained from a…

  5. Temporal and spatial changes in social vulnerability to natural hazards

    PubMed Central

    Cutter, Susan L.; Finch, Christina

    2008-01-01

    During the past four decades (1960–2000), the United States experienced major transformations in population size, development patterns, economic conditions, and social characteristics. These social, economic, and built-environment changes altered the American hazardscape in profound ways, with more people living in high-hazard areas than ever before. To improve emergency management, it is important to recognize the variability in the vulnerable populations exposed to hazards and to develop place-based emergency plans accordingly. The concept of social vulnerability identifies sensitive populations that may be less likely to respond to, cope with, and recover from a natural disaster. Social vulnerability is complex and dynamic, changing over space and through time. This paper presents empirical evidence on the spatial and temporal patterns in social vulnerability in the United States from 1960 to the present. Using counties as our study unit, we found that those components that consistently increased social vulnerability for all time periods were density (urban), race/ethnicity, and socioeconomic status. The spatial patterning of social vulnerability, although initially concentrated in certain geographic regions, has become more dispersed over time. The national trend shows a steady reduction in social vulnerability, but there is considerable regional variability, with many counties increasing in social vulnerability during the past five decades. PMID:18268336

  6. [Assessment of eco-environmental vulnerability of Hainan Island, China].

    PubMed

    Huang, Bao-rong; Ouyang, Zhi-yun; Zhang, Hui-zhi; Zhang, Li-hua; Zheng, Hua

    2009-03-01

    Based on the assessment method of environmental vulnerability constructed by SOPAC and UNEP, this paper constructed an indicator system from three sub-themes including hazard, resistance, and damage to assess the eco-environmental vulnerability of Hainan Island. The results showed that Hainan Island was suffering a middling level eco-environmental hazard, and the main hazards came from some intensive human activities such as intensive agriculture, mass tourism, mining, and a mass of solid wastes thrown by islanders and tourists. Some geographical characters such as larger land area, larger altitude range, integrated geographical form, and abundant habitat types endowed Hainan Island higher resistance to environmental hazards. However, disturbed by historical accumulative artificial and natural hazards, the Island ecosystem had showed serious ecological damage, such as soil degradation and biodiversity loss. Comprehensively considered hazard, resistance, damage, and degradation, the comprehensive environmental vulnerability of the Island was at a middling level. Some indicators showed lower vulnerability, but some showed higher vulnerability. PMID:19637604

  7. Analyses Of Two End-User Software Vulnerability Exposure Metrics

    SciTech Connect

    Jason L. Wright; Miles McQueen; Lawrence Wellman

    2012-08-01

    The risk due to software vulnerabilities will not be completely resolved in the near future. Instead, putting reliable vulnerability measures into the hands of end-users so that informed decisions can be made regarding the relative security exposure incurred by choosing one software package over another is of importance. To that end, we propose two new security metrics, average active vulnerabilities (AAV) and vulnerability free days (VFD). These metrics capture both the speed with which new vulnerabilities are reported to vendors and the rate at which software vendors fix them. We then examine how the metrics are computed using currently available datasets and demonstrate their estimation in a simulation experiment using four different browsers as a case study. Finally, we discuss how the metrics may be used by the various stakeholders of software and to software usage decisions.

  8. Nutritional Vulnerability in Older Adults: A Continuum of Concerns

    PubMed Central

    Porter Starr, Kathryn N.; McDonald, Shelley R.; Bales, Connie W.

    2015-01-01

    A nutritionally vulnerable older adult has a reduced physical reserve that limits the ability to mount a vigorous recovery in the face of an acute health threat or stressor. Often this vulnerability contributes to more medical complications, longer hospital stays, and increased likelihood of nursing home admission. We have characterized in this review the etiology of nutritional vulnerability across the continuum of the community, hospital, and long term care settings. Frail older adults may become less vulnerable with strong, consistent, and individualized nutritional care. Interventions for the vulnerable older adult must take their nutritional needs into account to optimize resiliency in the face of the acute and/or chronic health challenges they will surely face in their life course. PMID:26042189

  9. Transplanting Supersites of HIV-1 Vulnerability

    PubMed Central

    Yang, Yongping; Gorman, Jason; Ofek, Gilad; Srivatsan, Sanjay; Druz, Aliaksandr; Lees, Christopher R.; Lu, Gabriel; Soto, Cinque; Stuckey, Jonathan; Burton, Dennis R.; Koff, Wayne C.; Connors, Mark; Kwon, Peter D.

    2014-01-01

    One strategy for isolating or eliciting antibodies against a specific target region on the envelope glycoprotein trimer (Env) of the human immunodeficiency virus type 1 (HIV-1) involves the creation of site transplants, which present the target region on a heterologous protein scaffold with preserved antibody-binding properties. If the target region is a supersite of HIV-1 vulnerability, recognized by a collection of broadly neutralizing antibodies, this strategy affords the creation of “supersite transplants”, capable of binding (and potentially eliciting) antibodies similar to the template collection of effective antibodies. Here we transplant three supersites of HIV-1 vulnerability, each targeted by effective neutralizing antibodies from multiple donors. To implement our strategy, we chose a single representative antibody against each of the target supersites: antibody 10E8, which recognizes the membrane-proximal external region (MPER) on the HIV-1 gp41 glycoprotein; antibody PG9, which recognizes variable regions one and two (V1V2) on the HIV-1 gp120 glycoprotein; and antibody PGT128 which recognizes a glycopeptide supersite in variable region 3 (glycan V3) on gp120. We used a structural alignment algorithm to identify suitable acceptor proteins, and then designed, expressed, and tested antigenically over 100-supersite transplants in a 96-well microtiter-plate format. The majority of the supersite transplants failed to maintain the antigenic properties of their respective template supersite. However, seven of the glycan V3-supersite transplants exhibited nanomolar affinity to effective neutralizing antibodies from at least three donors and recapitulated the mannose9-N-linked glycan requirement of the template supersite. The binding of these transplants could be further enhanced by placement into self-assembling nanoparticles. Essential elements of the glycan V3 supersite, embodied by as few as 3 N-linked glycans and ?25 Env residues, can be segregated into acceptor scaffolds away from the immune-evading capabilities of the rest of HIV-1 Env, thereby providing a means to focus the immune response on the scaffolded supersite. PMID:24992528

  10. Regional vulnerability of longitudinal cortical association connectivity

    PubMed Central

    Ceschin, Rafael; Lee, Vince K.; Schmithorst, Vince; Panigrahy, Ashok

    2015-01-01

    Preterm born children with spastic diplegia type of cerebral palsy and white matter injury or periventricular leukomalacia (PVL), are known to have motor, visual and cognitive impairments. Most diffusion tensor imaging (DTI) studies performed in this group have demonstrated widespread abnormalities using averaged deterministic tractography and voxel-based DTI measurements. Little is known about structural network correlates of white matter topography and reorganization in preterm cerebral palsy, despite the availability of new therapies and the need for brain imaging biomarkers. Here, we combined novel post-processing methodology of probabilistic tractography data in this preterm cohort to improve spatial and regional delineation of longitudinal cortical association tract abnormalities using an along-tract approach, and compared these data to structural DTI cortical network topology analysis. DTI images were acquired on 16 preterm children with cerebral palsy (mean age 5.6 ± 4) and 75 healthy controls (mean age 5.7 ± 3.4). Despite mean tract analysis, Tract-Based Spatial Statistics (TBSS) and voxel-based morphometry (VBM) demonstrating diffusely reduced fractional anisotropy (FA) reduction in all white matter tracts, the along-tract analysis improved the detection of regional tract vulnerability. The along-tract map-structural network topology correlates revealed two associations: (1) reduced regional posterior–anterior gradient in FA of the longitudinal visual cortical association tracts (inferior fronto-occipital fasciculus, inferior longitudinal fasciculus, optic radiation, posterior thalamic radiation) correlated with reduced posterior–anterior gradient of intra-regional (nodal efficiency) metrics with relative sparing of frontal and temporal regions; and (2) reduced regional FA within frontal–thalamic–striatal white matter pathways (anterior limb/anterior thalamic radiation, superior longitudinal fasciculus and cortical spinal tract) correlated with alteration in eigenvector centrality, clustering coefficient (inter-regional) and participation co-efficient (inter-modular) alterations of frontal–striatal and fronto-limbic nodes suggesting re-organization of these pathways. Both along tract and structural topology network measurements correlated strongly with motor and visual clinical outcome scores. This study shows the value of combining along-tract analysis and structural network topology in depicting not only selective parietal occipital regional vulnerability but also reorganization of frontal–striatal and frontal–limbic pathways in preterm children with cerebral palsy. These finding also support the concept that widespread, but selective posterior–anterior neural network connectivity alterations in preterm children with cerebral palsy likely contribute to the pathogenesis of neurosensory and cognitive impairment in this group. PMID:26509119

  11. Tsunami survivors' perspectives on vulnerability and vulnerability reduction: evidence from Koh Phi Phi Don and Khao Lak, Thailand.

    PubMed

    Steckley, Marylynn; Doberstein, Brent

    2011-07-01

    This paper presents the results of primary research with 40 survivors of the 2004 Indian Ocean tsunami in two communities: Khao Lak (n=20) and Koh Phi Phi Don (n=20), Thailand. It traces tsunami survivors' perceptions of vulnerability, determines whether residents felt that the tsunami affected different communities differently, identifies the populations and sub-community groups that survivors distinguished as being more vulnerable than others, highlights community-generated ideas about vulnerability reduction, and pinpoints a range of additional vulnerability reduction actions. Tsunami survivors most consistently identified the 'most vulnerable' community sub-populations as women, children, the elderly, foreigners, and the poor. In Khao Lak, however, respondents added 'Burmese migrants' to this list, whereas in Koh Phi Phi Don, they added 'Thai Muslims'. Results suggest that the two case study communities, both small, coastal, tourism-dominated communities no more than 100 kilometres apart, have differing vulnerable sub-groups and environmental vulnerabilities, requiring different post-disaster vulnerability reduction efforts. PMID:21083848

  12. Environmental deterioration increases tadpole vulnerability to predation.

    PubMed

    Squires, Zoe E; Bailey, Paul C E; Reina, Richard D; Wong, Bob B M

    2008-08-23

    Human-induced environmental change is occurring at an unprecedented rate and scale. Many freshwater habitats, in particular, have been degraded as a result of increased salinity. Little is known about the effects of anthropogenic salinization on freshwater organisms, especially at sublethal concentrations, where subtle behavioural changes can have potentially drastic fitness consequences. Using a species of Australian frog (Litoria ewingii), we experimentally examined the effects of salinization on tadpole behaviour and their vulnerability to a predatory dragonfly nymph (Hemianax papuensis). We found that tadpoles exposed to an ecologically relevant concentration of salt (15% seawater, SW) were less active than those in our freshwater control (0.4% SW). Tadpoles in elevated salinity also experienced a higher risk of predation, even though the strike rate of the predator did not differ between salt and freshwater treatments. In a separate experiment testing the burst-speed performance of tadpoles, we found that tadpoles in saltwater were slower than those in freshwater. Thus, it would appear that salt compromised the anti-predator response of tadpoles and made them more susceptible to being captured. Our results demonstrate that environmentally relevant concentrations of aquatic contaminants can, even at sublethal levels, severely undermine the fitness of exposed organisms. PMID:18492650

  13. Somatostatin, neuronal vulnerability and behavioral emotionality

    PubMed Central

    Lin, LC; Sibille, E

    2014-01-01

    Somatostatin (SST) deficits are common pathological features in depression and other neurological disorders with mood disturbances, but little is known about the contribution of SST deficits to mood symptoms or causes of these deficits. Here we show that mice lacking Sst (SstKO) exhibit elevated behavioral emotionality, high basal plasma corticosterone and reduced gene expression of Bdnf, Cortistatin, and Gad67, together recapitulating behavioral, neuroendocrine and molecular features of human depression. Studies in SstKO and heterozygous (SstHZ) mice show that elevated corticosterone is not sufficient to reproduce the behavioral phenotype, suggesting a putative role for Sst cell-specific molecular changes. Using laser-capture microdissection, we show that cortical SST-positive interneurons display significantly greater transcriptome deregulations after chronic stress compared to pyramidal neurons. Protein translation through eukaryotic initiation factor 2 (EIF2) signaling, a pathway previously implicated in neurodegenerative diseases, was most affected and suppressed in stress-exposed SST neurons. We then show that activating EIF2 signaling through EIF2 kinase inhibition mitigated stress-induced behavioral emotionality in mice. Together, our data suggest that (1) low SST plays a causal role in mood-related phenotypes, (2) deregulated EIF2-mediated protein translation may represent a mechanism for vulnerability of SST neurons, and (3) that global EIF2 signaling has antidepressant/anxiolytic potential. PMID:25600109

  14. Tracking Nile Delta vulnerability to Holocene change.

    PubMed

    Marriner, Nick; Flaux, Clément; Morhange, Christophe; Stanley, Jean-Daniel

    2013-01-01

    Understanding deltaic resilience in the face of Holocene climate change and human impacts is an important challenge for the earth sciences in characterizing the full range of present and future wetland responses to global warming. Here, we report an 8000-year mass balance record from the Nile Delta to reconstruct when and how this sedimentary basin has responded to past hydrological shifts. In a global Holocene context, the long-term decrease in Nile Delta accretion rates is consistent with insolation-driven changes in the 'monsoon pacemaker', attested throughout the mid-latitude tropics. Following the early to mid-Holocene growth of the Nile's deltaic plain, sediment losses and pronounced erosion are first recorded after ~4000 years ago, the corollaries of falling sediment supply and an intensification of anthropogenic impacts from the Pharaonic period onwards. Against the backcloth of the Saharan 'depeopling', reduced river flow underpinned by a weakening of monsoonal precipitation appears to have been particularly conducive to the expansion of human activities on the delta by exposing productive floodplain lands for occupation and irrigation agriculture. The reconstruction suggests that the Nile Delta has a particularly long history of vulnerability to extreme events (e.g. floods and storms) and sea-level rise, although the present sediment-starved system does not have a direct Holocene analogue. This study highlights the importance of the world's deltas as sensitive archives to investigate Holocene geosystem responses to climate change, risks and hazards, and societal interaction. PMID:23922692

  15. Physiological Phenotype and Vulnerability in Parkinson's Disease

    PubMed Central

    Surmeier, D. James; Guzman, Jaime N.; Sanchez, Javier; Schumacker, Paul T.

    2012-01-01

    This review will focus on the principles underlying the hypothesis that neuronal physiological phenotype—how a neuron generates and regulates action potentials—makes a significant contribution to its vulnerability in Parkinson's disease (PD) and aging. A cornerstone of this hypothesis is that the maintenance of ionic gradients underlying excitability can pose a significant energetic burden for neurons, particularly those that have sustained residence times at depolarized membrane potentials, broad action potentials, prominent Ca2+ entry, and modest intrinsic Ca2+ buffering capacity. This energetic burden is shouldered in neurons primarily by mitochondria, the sites of cellular respiration. Mitochondrial respiration increases the production of damaging superoxide and other reactive oxygen species (ROS) that have widely been postulated to contribute to cellular aging and PD. Many of the genetic mutations and toxins associated with PD compromise mitochondrial function, providing a mechanistic linkage between known risk factors and cellular physiology that could explain the pattern of pathology in PD. Because much of the mitochondrial burden created by this at-risk phenotype is created by Ca2+ entry through L-type voltage-dependent channels for which there are antagonists approved for human use, a neuroprotective strategy to reduce this burden is feasible. PMID:22762023

  16. Quantum key distribution: vulnerable if imperfectly implemented

    NASA Astrophysics Data System (ADS)

    Leuchs, G.

    2013-10-01

    We report several vulnerabilities found in Clavis2, the flagship quantum key distribution (QKD) system from ID Quantique. We show the hacking of a calibration sequence run by Clavis2 to synchronize the Alice and Bob devices before performing the secret key exchange. This hack induces a temporal detection efficiency mismatch in Bob that can allow Eve to break the security of the cryptosystem using faked states. We also experimentally investigate the superlinear behaviour in the single-photon detectors (SPDs) used by Bob. Due to this superlinearity, the SPDs feature an actual multi-photon detection probability which is generally higher than the theoretically-modelled value. We show how this increases the risk of detector control attacks on QKD systems (including Clavis2) employing such SPDs. Finally, we review the experimental feasibility of Trojan-horse attacks. In the case of Clavis2, the objective is to read Bob's phase modulator to acquire knowledge of his basis choice as this information suffices for constructing the raw key in the Scarani-Acin-Ribordy-Gisin 2004 (SARG04) protocol. We work in close collaboration with ID Quantique and for all these loopholes, we notified them in advance. Wherever possible, we or ID Quantique proposed countermeasures and they implemented suitable patches and upgrade their systems.

  17. Risk assessment by dynamic representation of vulnerability, exploitation, and impact

    NASA Astrophysics Data System (ADS)

    Cam, Hasan

    2015-05-01

    Assessing and quantifying cyber risk accurately in real-time is essential to providing security and mission assurance in any system and network. This paper presents a modeling and dynamic analysis approach to assessing cyber risk of a network in real-time by representing dynamically its vulnerabilities, exploitations, and impact using integrated Bayesian network and Markov models. Given the set of vulnerabilities detected by a vulnerability scanner in a network, this paper addresses how its risk can be assessed by estimating in real-time the exploit likelihood and impact of vulnerability exploitation on the network, based on real-time observations and measurements over the network. The dynamic representation of the network in terms of its vulnerabilities, sensor measurements, and observations is constructed dynamically using the integrated Bayesian network and Markov models. The transition rates of outgoing and incoming links of states in hidden Markov models are used in determining exploit likelihood and impact of attacks, whereas emission rates help quantify the attack states of vulnerabilities. Simulation results show the quantification and evolving risk scores over time for individual and aggregated vulnerabilities of a network.

  18. An Extreme-Value Approach to Anomaly Vulnerability Identification

    NASA Technical Reports Server (NTRS)

    Everett, Chris; Maggio, Gaspare; Groen, Frank

    2010-01-01

    The objective of this paper is to present a method for importance analysis in parametric probabilistic modeling where the result of interest is the identification of potential engineering vulnerabilities associated with postulated anomalies in system behavior. In the context of Accident Precursor Analysis (APA), under which this method has been developed, these vulnerabilities, designated as anomaly vulnerabilities, are conditions that produce high risk in the presence of anomalous system behavior. The method defines a parameter-specific Parameter Vulnerability Importance measure (PVI), which identifies anomaly risk-model parameter values that indicate the potential presence of anomaly vulnerabilities, and allows them to be prioritized for further investigation. This entails analyzing each uncertain risk-model parameter over its credible range of values to determine where it produces the maximum risk. A parameter that produces high system risk for a particular range of values suggests that the system is vulnerable to the modeled anomalous conditions, if indeed the true parameter value lies in that range. Thus, PVI analysis provides a means of identifying and prioritizing anomaly-related engineering issues that at the very least warrant improved understanding to reduce uncertainty, such that true vulnerabilities may be identified and proper corrective actions taken.

  19. Soil compaction vulnerability at Organ Pipe Cactus National Monument, Arizona

    USGS Publications Warehouse

    Webb, Robert H.; Nussear, Kenneth E.; Carmichael, Shinji; Esque, Todd C.

    2014-01-01

    Compaction vulnerability of different types of soils by hikers and vehicles is poorly known, particularly for soils of arid and semiarid regions. Engineering analyses have long shown that poorly sorted soils (for example, sandy loams) compact to high densities, whereas well-sorted soils (for example, eolian sand) do not compact, and high gravel content may reduce compaction. Organ Pipe Cactus National Monument (ORPI) in southwestern Arizona, is affected greatly by illicit activities associated with the United States–Mexico border, and has many soils that resource managers consider to be highly vulnerable to compaction. Using geospatial soils data for ORPI, compaction vulnerability was estimated qualitatively based on the amount of gravel and the degree of sorting of sand and finer particles. To test this qualitative assessment, soil samples were collected from 48 sites across all soil map units, and undisturbed bulk densities were measured. A scoring system was used to create a vulnerability index for soils on the basis of particle-size sorting, soil properties derived from Proctor compaction analyses, and the field undisturbed bulk densities. The results of the laboratory analyses indicated that the qualitative assessments of soil compaction vulnerability underestimated the area of high vulnerability soils by 73 percent. The results showed that compaction vulnerability of desert soils, such as those at ORPI, can be quantified using laboratory tests and evaluated using geographic information system analyses, providing a management tool that managers potentially could use to inform decisions about activities that reduce this type of soil disruption in protected areas.

  20. Groundwater vulnerability to pollution mapping of Ranchi district using GIS

    NASA Astrophysics Data System (ADS)

    Krishna, R.; Iqbal, J.; Gorai, A. K.; Pathak, G.; Tuluri, F.; Tchounwou, P. B.

    2015-12-01

    Groundwater pollution due to anthropogenic activities is one of the major environmental problems in urban and industrial areas. The present study demonstrates the integrated approach with GIS and DRASTIC model to derive a groundwater vulnerability to pollution map. The model considers the seven hydrogeological factors [Depth to water table ( D), net recharge ( R), aquifer media ( A), soil media ( S), topography or slope ( T), impact of vadose zone ( I) and hydraulic Conductivity( C)] for generating the groundwater vulnerability to pollution map. The model was applied for assessing the groundwater vulnerability to pollution in Ranchi district, Jharkhand, India. The model was validated by comparing the model output (vulnerability indices) with the observed nitrate concentrations in groundwater in the study area. The reason behind the selection of nitrate is that the major sources of nitrate in groundwater are anthropogenic in nature. Groundwater samples were collected from 30 wells/tube wells distributed in the study area. The samples were analyzed in the laboratory for measuring the nitrate concentrations in groundwater. A sensitivity analysis of the integrated model was performed to evaluate the influence of single parameters on groundwater vulnerability index. New weights were computed for each input parameters to understand the influence of individual hydrogeological factors in vulnerability indices in the study area. Aquifer vulnerability maps generated in this study can be used for environmental planning and groundwater management.

  1. Assessing the vulnerability of buildings to tsunami in Sydney

    NASA Astrophysics Data System (ADS)

    Dall'Osso, F.; Gonella, M.; Gabbianelli, G.; Withycombe, G.; Dominey-Howes, D.

    2009-12-01

    Australia is vulnerable to the impacts of tsunamis and exposure along the SE coast of New South Wales is especially high. Significantly, this is the same area reported to have been affected by repeated large magnitude tsunamis during the Holocene. Efforts are under way to complete probabilistic risk assessments for the region but local government planners and emergency risk managers need information now about building vulnerability in order to develop appropriate risk management strategies. We use the newly revised PTVA-3 Model (Dall'Osso et al., 2009) to assess the relative vulnerability of buildings to damage from a "worst case tsunami" defined by our latest understanding of regional risk - something never before undertaken in Australia. We present selected results from an investigation of building vulnerability within the local government area of Manly - an iconic coastal area of Sydney. We show that a significant proportion of buildings (in particular, residential structures) are classified as having "High" and "Very High" Relative Vulnerability Index scores. Furthermore, other important buildings (e.g., schools, nursing homes and transport structures) are also vulnerable to damage. Our results have serious implications for immediate emergency risk management, longer-term land-use zoning and development, and building design and construction standards. Based on the work undertaken here, we recommend further detailed assessment of the vulnerability of coastal buildings in at risk areas, development of appropriate risk management strategies and a detailed program of community engagement to increase overall resilience.

  2. Groundwater vulnerability to pollution mapping of Ranchi district using GIS

    PubMed Central

    Krishna, R.; Iqbal, J.; Pathak, G.; Tuluri, F.; Tchounwou, P. B.

    2015-01-01

    Groundwater pollution due to anthropogenic activities is one of the major environmental problems in urban and industrial areas. The present study demonstrates the integrated approach with GIS and DRASTIC model to derive a groundwater vulnerability to pollution map. The model considers the seven hydrogeological factors [Depth to water table (D), net recharge (R), aquifer media (A), soil media (S), topography or slope (T), impact of vadose zone (I) and hydraulic Conductivity(C)] for generating the groundwater vulnerability to pollution map. The model was applied for assessing the groundwater vulnerability to pollution in Ranchi district, Jharkhand, India. The model was validated by comparing the model output (vulnerability indices) with the observed nitrate concentrations in groundwater in the study area. The reason behind the selection of nitrate is that the major sources of nitrate in groundwater are anthropogenic in nature. Groundwater samples were collected from 30 wells/tube wells distributed in the study area. The samples were analyzed in the laboratory for measuring the nitrate concentrations in groundwater. A sensitivity analysis of the integrated model was performed to evaluate the influence of single parameters on groundwater vulnerability index. New weights were computed for each input parameters to understand the influence of individual hydrogeological factors in vulnerability indices in the study area. Aquifer vulnerability maps generated in this study can be used for environmental planning and groundwater management. PMID:26557470

  3. EDITORIAL: Groundwater resources, climate and vulnerability Groundwater resources, climate and vulnerability

    NASA Astrophysics Data System (ADS)

    Bovolo, C. Isabella; Parkin, Geoff; Sophocleous, Marios

    2009-09-01

    Groundwater is an important component of the freshwater system and its role is becoming even more prominent as the more accessible surface water resources become increasingly exploited to support increasing populations and development. Yet despite its significance, there has been comparatively little research conducted on groundwater relative to surface water resources, particularly in the context of climate change impact assessment. This focus issue has therefore been assembled to expand upon the currently limited knowledge of groundwater systems and their links with climate. Many of the papers included here explore the interrelated issues of groundwater resources, climate-related changes and vulnerabilities at a regional scale in different continents and globally. See the PDF for the full text of the editorial. Focus on Groundwater Resources, Climate and Vulnerability Contents Groundwater: from mystery to management T N Narasimhan Simulated response of groundwater to predicted recharge in a semi-arid region using a scenario of modelled climate change M W Toews and D M Allen Long-term climatic change and sustainable ground water resources management Hugo A Loáiciga Climate change and groundwater: India's opportunities for mitigation and adaptation Tushaar Shah Vulnerability to the impact of climate change on renewable groundwater resources: a global-scale assessment Petra Döll Influence of soil heterogeneity on evapotranspiration under shallow water table conditions: transient, stochastic simulations Stefan J Kollet Nutrient cycling and N2O emissions in a changing climate: the subsurface water system role Georgia Destouni and Amélie Darracq Rainfall intensity and groundwater recharge: empirical evidence from the Upper Nile Basin M Owor, R G Taylor, C Tindimugaya and D Mwesigwa

  4. EDITORIAL: Groundwater resources, climate and vulnerability Groundwater resources, climate and vulnerability

    NASA Astrophysics Data System (ADS)

    Bovolo, C. Isabella; Parkin, Geoff; Sophocleous, Marios

    2009-09-01

    Groundwater is an important component of the freshwater system and its role is becoming even more prominent as the more accessible surface water resources become increasingly exploited to support increasing populations and development. Yet despite its significance, there has been comparatively little research conducted on groundwater relative to surface water resources, particularly in the context of climate change impact assessment. This focus issue has therefore been assembled to expand upon the currently limited knowledge of groundwater systems and their links with climate. Many of the papers included here explore the interrelated issues of groundwater resources, climate-related changes and vulnerabilities at a regional scale in different continents and globally. See the PDF for the full text of the editorial. Focus on Groundwater Resources, Climate and Vulnerability Contents Groundwater: from mystery to management T N Narasimhan Simulated response of groundwater to predicted recharge in a semi-arid region using a scenario of modelled climate change M W Toews and D M Allen Long-term climatic change and sustainable ground water resources management Hugo A Loáiciga Climate change and groundwater: India's opportunities for mitigation and adaptation Tushaar Shah Vulnerability to the impact of climate change on renewable groundwater resources: a global-scale assessment Petra Döll Influence of soil heterogeneity on evapotranspiration under shallow water table conditions: transient, stochastic simulations Stefan J Kollet Nutrient cycling and N2O emissions in a changing climate: the subsurface water system role Georgia Destouni and Amélie Darracq Rainfall intensity and groundwater recharge: empirical evidence from the Upper Nile Basin M Owor, R G Taylor, C Tindimugaya and D Mwesigwa This focus issue is not yet complete, there are still letters at press and in review.

  5. Examining dimensions of vulnerability among children in Uganda.

    PubMed

    Kalibala, Samuel; Schenk, Katie D; Weiss, Deborah C; Elson, Lynne

    2012-01-01

    Insufficient data on the nature and extent of children's vulnerability in Uganda has challenged government and donors in priority setting, resource allocation and developing effective approaches to improve well-being. We conducted a population-based survey among a nationally representative sample of 2551 households, covering a total of 7946 children. We engaged national stakeholders in a priority-setting exercise to develop a scoring system to assess dimensions of children's vulnerability. The exercise identified individual and household characteristics to assess vulnerability--many of which had not been measured previously--to which numerical weights representing vulnerability level were assigned. Highly weighted characteristics included maternal death, disability, child labour and pregnancy before age 17. Psychosocial elements included living apart from siblings, having nobody to talk to and never visiting a living parent. According to this approach, an estimated 51.1% of children in Uganda (weighted for national population distribution) are considered critically or moderately vulnerable. It is to these children, equivalent to a national total of 8.7 million, that support services should be prioritised. However, survey data suggest that the most critically vulnerable children are under-represented in several types of support services. This pioneering, participatory methodology provides a rudimentary, but valuable, first step towards quantifying the vulnerability of children in Uganda and assessing their resource needs. It has been used by the Government of Uganda to determine subcategories of vulnerability for resource allocation. A major advantage is that it uses local contextual knowledge of child vulnerability rather than generic criteria applied in international surveys. Further analytical work is required to validate the methodology, link it to child well-being outcomes and devise a practical tool for service providers to refine programme targeting. The approach may be useful to national, regional or local service providers seeking an overview of their client base to monitor and improve programme-targeting efforts. PMID:21797733

  6. Attending to social vulnerability when rationing pandemic resources.

    PubMed

    Vawter, Dorothy E; Garrett, J Eline; Gervais, Karen G; Prehn, Angela Witt; DeBruin, Debra A

    2011-01-01

    Pandemic plans are increasingly attending to groups experiencing health disparities and other social vulnerabilities. Although some pandemic guidance is silent on the issue, guidance that attends to socially vulnerable groups ranges widely, some procedural (often calling for public engagement), and some substantive. Public engagement objectives vary from merely educational to seeking reflective input into the ethical commitments that should guide pandemic planning and response. Some plans that concern rationing during a severe pandemic recommend ways to protect socially vulnerable groups without prioritizing access to scarce resources based on social vulnerability per se. The Minnesota Pandemic Ethics Project (MPEP), a public engagement project on rationing scarce health resources during a severe influenza pandemic, agrees and recommends an integrated set of ways to attend to the needs of socially vulnerable people and avoid exacerbation of health disparities during a severe influenza pandemic. Among other things, MPEP recommends: 1. Engaging socially vulnerable populations to clarify unique needs and effective strategies; 2. Engaging socially vulnerable populations to elicit ethical values and perspectives on rationing; 3. Rejecting rationing based on race, socioeconomic class, citizenship, quality of life, length of life-extension and first-come, first-served; 4. Prioritizing those in the general population for access to resources based on combinations of risk (of death or severe complications from influenza, exposure to influenza, transmitting influenza to vulnerable groups) and the likelihood of responding well to the resource in question. 5. Protecting critical infrastructures on which vulnerable populations and the general public rely; 6. Identifying and removing access barriers during pandemic planning and response; and 7. Collecting and promptly analyzing data during the pandemic to identify groups at disproportionate risk of influenza-related mortality and serious morbidity and to optimize the distribution of resources. PMID:21595354

  7. Volcanic risk assessment: Quantifying physical vulnerability in the built environment

    NASA Astrophysics Data System (ADS)

    Jenkins, S. F.; Spence, R. J. S.; Fonseca, J. F. B. D.; Solidum, R. U.; Wilson, T. M.

    2014-04-01

    This paper presents structured and cost-effective methods for assessing the physical vulnerability of at-risk communities to the range of volcanic hazards, developed as part of the MIA-VITA project (2009-2012). An initial assessment of building and infrastructure vulnerability has been carried out for a set of broadly defined building types and infrastructure categories, with the likelihood of damage considered separately for projectile impact, ash fall loading, pyroclastic density current dynamic pressure and earthquake ground shaking intensities. In refining these estimates for two case study areas: Kanlaon volcano in the Philippines and Fogo volcano in Cape Verde, we have developed guidelines and methodologies for carrying out physical vulnerability assessments in the field. These include identifying primary building characteristics, such as construction material and method, as well as subsidiary characteristics, for example the size and prevalence of openings, that may be important in assessing eruption impacts. At-risk buildings around Kanlaon were found to be dominated by timber frame buildings that exhibit a high vulnerability to pyroclastic density currents, but a low vulnerability to failure from seismic shaking. Around Fogo, the predominance of unreinforced masonry buildings with reinforced concrete slab roofs suggests a high vulnerability to volcanic earthquake but a low vulnerability to ash fall loading. Given the importance of agriculture for local livelihoods around Kanlaon and Fogo, we discuss the potential impact of infrastructure vulnerability for local agricultural economies, with implications for volcanic areas worldwide. These methodologies and tools go some way towards offering a standardised approach to carrying out future vulnerability assessments for populated volcanic areas.

  8. Vulnerability of the Ecuador's Agricultural Sector as part of an Integrated Climate Change Vulnerability Study

    NASA Astrophysics Data System (ADS)

    Flores-Lopez, F.; Depsky, N. J.

    2014-12-01

    Earlier this year SEI, in conjunction with the Environmental Secretary of Quito, concluded a vulnerability analysis for the Metropolitan District of Quito (DMQ). The study analyzed future anthropogenic and natural hazards, and how these threats may be potentially exacerbated by a changing climate over the next 40 years. The focus of this abstract is specifically on the vulnerability of the agricultural sector.Overall, there is a lack of consensus amongst the results of long-term trends of precipitation in the Quito region. However, there is much more confidence in the trends of mean air temperature increase, and therefore this analysis focused specifically upon the effects of increasing temperatures upon Quito's agricultural sector. Effects of a roughly 2°C increase in mean air temperature by 2050 (corresponding to a relative CO2 concentration pathway within the GCMs of 8.5) was evaluated with respect to its potential effects upon the length of growing season for principal crops, and which of these crops are most vulnerable to the increased heat stress. Also studied was the potential expansion of agriculture into higher elevation areas, namely the sensitive 'paramo' alpine ecosystem, due to increasing arability of these areas as temperatures rise. The extent of cultivation of 'paramos' areas was estimated in order to assess the likely diminutive effects upon local hydrology and ecosystem well-being.Our results show that in fact it is expected that the increase in temperature would have a positive effect on the development of some crops, though the growing seasons would likely be shortened, which may be problematic given soil and rainfall constraints.Regarding expansion of agriculture into the 'paramo' highlands, results showed that each 200m zone above 3400masl would experience a marked increase in agricultural land conversion, ranging from 15 - 55km2, depending upon the zone. The lowest zones are expectedly the most vulnerable as they already exist at the interface of the current agricultural frontier. The need for additional adaptation, conservation, and land management planning initiatives in the region are echoed by these results, as well as need for further scrutiny of these issues under additional scenarios and sectoral lenses in order to best inform smart policy making in the DMQ.

  9. Vulnerability Assessment for Cascading Failures in Electric Power Systems

    SciTech Connect

    Baldick, R.; Chowdhury, Badrul; Dobson, Ian; Dong, Zhao Yang; Gou, Bei; Hawkins, David L.; Huang, Zhenyu; Joung, Manho; Kim, Janghoon; Kirschen, Daniel; Lee, Stephen; Li, Fangxing; Li, Juan; Li, Zuyi; Liu, Chen-Ching; Luo, Xiaochuan; Mili, Lamine; Miller, Stephen; Nakayama, Marvin; Papic, Milorad; Podmore, Robin; Rossmaier, John; Schneider, Kevin P.; Sun, Hongbin; Sun, Kai; Wang, David; Wu, Zhigang; Yao, Liangzhong; Zhang, Pei; Zhang, Wenjie; Zhang, Xiaoping

    2008-09-10

    Cascading failures present severe threats to power grid security, and thus vulnerability assessment of power grids is of significant importance. Focusing on analytic methods, this paper reviews the state of the art of vulnerability assessment methods in the context of cascading failures in three categories: steady-state modeling based analysis; dynamic modeling analysis; and non-traditional modeling approaches. The impact of emerging technologies including phasor technology, high-performance computing techniques, and visualization techniques on the vulnerability assessment of cascading failures is then addressed, and future research directions are presented.

  10. Drought vulnerability assessment for prioritising drought warning implementation

    NASA Astrophysics Data System (ADS)

    Naumann, Gustavo; Faneca Sànchez, Marta; Mwangi, Emmah; Barbosa, Paulo; Iglesias, Ana; Garrote, Luis; Werner, Micha

    2014-05-01

    Drought warning provides a potentially efficient approach to mitigation of drought impacts, and should be targeted at areas most vulnerable to being adversely impacted. Assessing drought vulnerability is, however, complex and needs to consider susceptibility to drought impact as well as the capacity to cope with drought. In this paper a Drought Vulnerability Index (DVI) is proposed that considers four primary components that reflect the capacity of society to adapt to drought; the renewable natural capital, the economic capacity, the human and civic resources, and the available infrastructure and technology. The DVI is established as a weighted combination of these four components, each a composite of selected indicators. Constituent indicators are calculated based on national and/or regional census data and statistics, and while the resulting DVI should not be considered an absolute measure of drought vulnerability it does provide for a prioritisation of areas that can be used to target drought warning efforts. Sensitivity analysis of weights applied show the established DVI to be robust. Through the DVI the development of drought forecasting and warning can be targeted at the most vulnerable areas. The proposed DVI is applied at both the continental scale in Africa to assess drought vulnerability of the different nations across Africa, and at the national level in Kenya, allowing for prioritisation of the counties within Kenya to drought vulnerability. Results show the relative vulnerability of countries and counties vulnerable to drought. At the continental scale, Somalia, Burundi, Niger, Ethiopia, Mali and Chad are found to be the countries most vulnerable to drought. At the national level, the relative vulnerability of the counties across Kenya is found, with counties in the North-East of Kenya having the highest values of DVI. At the country level results were compared with drought disaster information from the EM-DAT disaster database, showing a good agreement between recorded drought impact and the established DVI classes. Kenya counties most vulnerable to drought are primarily located in the North-East of the country, showing a reasonable agreement with the spatial distribution of impacts of the 2010/2011 drought, despite the drought itself being more widespread.

  11. Automated Vulnerability Detection for Compiled Smart Grid Software

    SciTech Connect

    Prowell, Stacy J; Pleszkoch, Mark G; Sayre, Kirk D; Linger, Richard C

    2012-01-01

    While testing performed with proper experimental controls can provide scientifically quantifiable evidence that software does not contain unintentional vulnerabilities (bugs), it is insufficient to show that intentional vulnerabilities exist, and impractical to certify devices for the expected long lifetimes of use. For both of these needs, rigorous analysis of the software itself is essential. Automated software behavior computation applies rigorous static software analysis methods based on function extraction (FX) to compiled software to detect vulnerabilities, intentional or unintentional, and to verify critical functionality. This analysis is based on the compiled firmware, takes into account machine precision, and does not rely on heuristics or approximations early in the analysis.

  12. Perfectionism and Depression: Vulnerabilities Nurses Need to Understand

    PubMed Central

    Melrose, Sherri

    2011-01-01

    Striving for excellence is an admirable goal. Adaptive or healthy perfectionism can drive ambition and lead to extraordinary accomplishments. High-achieving people often show signs of perfectionism. However, maladaptive, unhealthy, or neurotic perfectionism, where anything less than perfect is unacceptable, can leave individuals vulnerable to depression. In both personal and professional relationships, nurses need to understand how accepting only perfection in self and others is likely to lead to emotional distress. This paper reviews perfectionism as a personality style, comments on perfectionism and high achievement, discusses vulnerabilities to depression, identifies how to recognize perfectionists, and presents balancing strategies perfectionists can implement to lessen their vulnerability to depression. PMID:21994842

  13. Vulnerability of Rural Hospitals to Medicare Outpatient Payment Reform

    PubMed Central

    Mohr, Penny E.; Franco, Sheila J.; Blanchfield, Bonnie B.; Cheng, C. Michael; Evans, William N.

    1999-01-01

    Because the Balanced Budget Act (BBA) of 1997 requires implementation of a Medicare prospective payment system (PPS) for hospital outpatient services, the authors evaluated the potential impact of outpatient PPS on rural hospitals. Areas examined include: (1) How dependent are rural hospitals on outpatient revenue? (2) Are they more likely than urban hospitals to be vulnerable to payment reform? (3) What types of rural hospitals will be most vulnerable to reform? Using Medicare cost report data, the authors found that small size and government ownership are more common among rural than urban hospitals and are the most important determinants of vulnerability to payment reform. PMID:11481724

  14. Tracking Nile Delta Vulnerability to Holocene Change

    PubMed Central

    Marriner, Nick; Flaux, Clément; Morhange, Christophe; Stanley, Jean-Daniel

    2013-01-01

    Understanding deltaic resilience in the face of Holocene climate change and human impacts is an important challenge for the earth sciences in characterizing the full range of present and future wetland responses to global warming. Here, we report an 8000-year mass balance record from the Nile Delta to reconstruct when and how this sedimentary basin has responded to past hydrological shifts. In a global Holocene context, the long-term decrease in Nile Delta accretion rates is consistent with insolation-driven changes in the ‘monsoon pacemaker’, attested throughout the mid-latitude tropics. Following the early to mid-Holocene growth of the Nile’s deltaic plain, sediment losses and pronounced erosion are first recorded after ~4000 years ago, the corollaries of falling sediment supply and an intensification of anthropogenic impacts from the Pharaonic period onwards. Against the backcloth of the Saharan ‘depeopling’, reduced river flow underpinned by a weakening of monsoonal precipitation appears to have been particularly conducive to the expansion of human activities on the delta by exposing productive floodplain lands for occupation and irrigation agriculture. The reconstruction suggests that the Nile Delta has a particularly long history of vulnerability to extreme events (e.g. floods and storms) and sea-level rise, although the present sediment-starved system does not have a direct Holocene analogue. This study highlights the importance of the world’s deltas as sensitive archives to investigate Holocene geosystem responses to climate change, risks and hazards, and societal interaction. PMID:23922692

  15. Ultrasound Tissue Characterization of Vulnerable Atherosclerotic Plaque

    PubMed Central

    Picano, Eugenio; Paterni, Marco

    2015-01-01

    A thrombotic occlusion of the vessel fed by ruptured coronary atherosclerotic plaque may result in unstable angina, myocardial infarction or death, whereas embolization from a plaque in carotid arteries may result in transient ischemic attack or stroke. The atherosclerotic plaque prone to such clinical events is termed high-risk or vulnerable plaque, and its identification in humans before it becomes symptomatic has been elusive to date. Ultrasonic tissue characterization of the atherosclerotic plaque is possible with different techniques—such as vascular, transesophageal, and intravascular ultrasound—on a variety of arterial segments, including carotid, aorta, and coronary districts. The image analysis can be based on visual, video-densitometric or radiofrequency methods and identifies three distinct textural patterns: hypo-echoic (corresponding to lipid- and hemorrhage-rich plaque), iso- or moderately hyper-echoic (fibrotic or fibro-fatty plaque), and markedly hyperechoic with shadowing (calcific plaque). Hypoechoic or dishomogeneous plaques, with spotty microcalcification and large plaque burden, with plaque neovascularization and surface irregularities by contrast-enhanced ultrasound, are more prone to clinical complications than hyperechoic, extensively calcified, homogeneous plaques with limited plaque burden, smooth luminal plaque surface and absence of neovascularization. Plaque ultrasound morphology is important, along with plaque geometry, in determining the atherosclerotic prognostic burden in the individual patient. New quantitative methods beyond backscatter (to include speed of sound, attenuation, strain, temperature, and high order statistics) are under development to evaluate vascular tissues. Although not yet ready for widespread clinical use, tissue characterization is listed by the American Society of Echocardiography roadmap to 2020 as one of the most promising fields of application in cardiovascular ultrasound imaging, offering unique opportunities for the early detection and treatment of atherosclerotic disease. PMID:25950760

  16. Vulnerability of critical infrastructures : identifying critical nodes.

    SciTech Connect

    Cox, Roger Gary; Robinson, David Gerald

    2004-06-01

    The objective of this research was the development of tools and techniques for the identification of critical nodes within critical infrastructures. These are nodes that, if disrupted through natural events or terrorist action, would cause the most widespread, immediate damage. This research focuses on one particular element of the national infrastructure: the bulk power system. Through the identification of critical elements and the quantification of the consequences of their failure, site-specific vulnerability analyses can be focused at those locations where additional security measures could be effectively implemented. In particular, with appropriate sizing and placement within the grid, distributed generation in the form of regional power parks may reduce or even prevent the impact of widespread network power outages. Even without additional security measures, increased awareness of sensitive power grid locations can provide a basis for more effective national, state and local emergency planning. A number of methods for identifying critical nodes were investigated: small-world (or network theory), polyhedral dynamics, and an artificial intelligence-based search method - particle swarm optimization. PSO was found to be the only viable approach and was applied to a variety of industry accepted test networks to validate the ability of the approach to identify sets of critical nodes. The approach was coded in a software package called Buzzard and integrated with a traditional power flow code. A number of industry accepted test networks were employed to validate the approach. The techniques (and software) are not unique to power grid network, but could be applied to a variety of complex, interacting infrastructures.

  17. Rockfall vulnerability assessment for masonry buildings

    NASA Astrophysics Data System (ADS)

    Mavrouli, Olga

    2015-04-01

    The methodologies for the quantitative risk assessment vary in function of the application scale and the available data. For fragmental rockfalls, risk calculation requires data for the expected damage of the exposed elements due to potential rock block impacts with a range of trajectories, magnitudes and intensities. Although the procedures for the quantification of the rock block characteristics in terms of magnitude-frequency relationships are well established, there are few methodologies for the calculation of the vulnerability, and these are usually empirical or judgmental. The response of buildings to rock block impacts using analytical methods has been mainly realised so far for reinforced concrete buildings, and some fragility curves have been calculated with the results, indicating the potential damage for a range of rock block characteristics. Masonry buildings, as a common structural typology in mountainous areas, are in many cases impacted by rock blocks during rockfalls. Their response presents some peculiarities in comparison with reinforced-concrete structures given the non-homogeneity and variability of the compound materials (blocks and mortar), their orthotropy, low strength in tension, the statically indeterminate load-bearing system and the non-monolithic connections. To this purpose, analytical procedures which are specifically adapted to masonry structures should be used for the evaluation of the expected damage due to rock impacts. In this contribution we discuss the application of the analytical approach for the assessment of the expected damage in rockfall prone areas and the simulation assumptions that can be made concerning the materials, geometry, loading and the relevant simplifications. The amount of uncertainties introduced during their analytical simulation is high due to the dispersion of the data for material mechanical properties and the construction techniques and quality and thus a probabilistic assessment is suggested. The random nature of the rockfall as far as it concerns the magnitude and the intensity of the rock blocks can also be introduced using parametric analyses.

  18. Early brain vulnerability in Wolfram syndrome.

    PubMed

    Hershey, Tamara; Lugar, Heather M; Shimony, Joshua S; Rutlin, Jerrel; Koller, Jonathan M; Perantie, Dana C; Paciorkowski, Alex R; Eisenstein, Sarah A; Permutt, M Alan

    2012-01-01

    Wolfram Syndrome (WFS) is a rare autosomal recessive disease characterized by insulin-dependent diabetes mellitus, optic nerve atrophy, diabetes insipidus, deafness, and neurological dysfunction leading to death in mid-adulthood. WFS is caused by mutations in the WFS1 gene, which lead to endoplasmic reticulum (ER) stress-mediated cell death. Case studies have found widespread brain atrophy in late stage WFS. However, it is not known when in the disease course these brain abnormalities arise, and whether there is differential vulnerability across brain regions and tissue classes. To address this limitation, we quantified regional brain abnormalities across multiple imaging modalities in a cohort of young patients in relatively early stages of WFS. Children and young adults with WFS were evaluated with neurological, cognitive and structural magnetic resonance imaging measures. Compared to normative data, the WFS group had intact cognition, significant anxiety and depression, and gait abnormalities. Compared to healthy and type 1 diabetic control groups, the WFS group had smaller intracranial volume and preferentially affected gray matter volume and white matter microstructural integrity in the brainstem, cerebellum and optic radiations. Abnormalities were detected in even the youngest patients with mildest symptoms, and some measures did not follow the typical age-dependent developmental trajectory. These results establish that WFS is associated with smaller intracranial volume with specific abnormalities in the brainstem and cerebellum, even at the earliest stage of clinical symptoms. This pattern of abnormalities suggests that WFS has a pronounced impact on early brain development in addition to later neurodegenerative effects, representing a significant new insight into the WFS disease process. Longitudinal studies will be critical for confirming and expanding our understanding of the impact of ER stress dysregulation on brain development. PMID:22792385

  19. Ultrasound tissue characterization of vulnerable atherosclerotic plaque.

    PubMed

    Picano, Eugenio; Paterni, Marco

    2015-01-01

    A thrombotic occlusion of the vessel fed by ruptured coronary atherosclerotic plaque may result in unstable angina, myocardial infarction or death, whereas embolization from a plaque in carotid arteries may result in transient ischemic attack or stroke. The atherosclerotic plaque prone to such clinical events is termed high-risk or vulnerable plaque, and its identification in humans before it becomes symptomatic has been elusive to date. Ultrasonic tissue characterization of the atherosclerotic plaque is possible with different techniques--such as vascular, transesophageal, and intravascular ultrasound--on a variety of arterial segments, including carotid, aorta, and coronary districts. The image analysis can be based on visual, video-densitometric or radiofrequency methods and identifies three distinct textural patterns: hypo-echoic (corresponding to lipid- and hemorrhage-rich plaque), iso- or moderately hyper-echoic (fibrotic or fibro-fatty plaque), and markedly hyperechoic with shadowing (calcific plaque). Hypoechoic or dishomogeneous plaques, with spotty microcalcification and large plaque burden, with plaque neovascularization and surface irregularities by contrast-enhanced ultrasound, are more prone to clinical complications than hyperechoic, extensively calcified, homogeneous plaques with limited plaque burden, smooth luminal plaque surface and absence of neovascularization. Plaque ultrasound morphology is important, along with plaque geometry, in determining the atherosclerotic prognostic burden in the individual patient. New quantitative methods beyond backscatter (to include speed of sound, attenuation, strain, temperature, and high order statistics) are under development to evaluate vascular tissues. Although not yet ready for widespread clinical use, tissue characterization is listed by the American Society of Echocardiography roadmap to 2020 as one of the most promising fields of application in cardiovascular ultrasound imaging, offering unique opportunities for the early detection and treatment of atherosclerotic disease. PMID:25950760

  20. 77 FR 28894 - Maritime Vulnerability Self-Assessment Tool

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    ...-1933, email TSA-OSCCommunications@tsa.dhs.gov . SUPPLEMENTARY INFORMATION: On December 5, 2003 (68 FR... SECURITY Transportation Security Administration Maritime Vulnerability Self-Assessment Tool AGENCY...- assessment tool. SUMMARY: The Transportation Security Administration (TSA) announces that the TSA...

  1. Soft Error Vulnerability of Iterative Linear Algebra Methods

    SciTech Connect

    Bronevetsky, G; de Supinski, B

    2008-01-19

    Devices are increasingly vulnerable to soft errors as their feature sizes shrink. Previously, soft error rates were significant primarily in space and high-atmospheric computing. Modern architectures now use features so small at sufficiently low voltages that soft errors are becoming important even at terrestrial altitudes. Due to their large number of components, supercomputers are particularly susceptible to soft errors. Since many large scale parallel scientific applications use iterative linear algebra methods, the soft error vulnerability of these methods constitutes a large fraction of the applications overall vulnerability. Many users consider these methods invulnerable to most soft errors since they converge from an imprecise solution to a precise one. However, we show in this paper that iterative methods are vulnerable to soft errors, exhibiting both silent data corruptions and poor ability to detect errors. Further, we evaluate a variety of soft error detection and tolerance techniques, including checkpointing, linear matrix encodings, and residual tracking techniques.

  2. Rethinking the vulnerability of minority populations in research.

    PubMed

    Rogers, Wendy; Lange, Margaret Meek

    2013-12-01

    The Belmont Report, produced in 1979 by a United States government commission, includes minority populations among its list of vulnerable research participants. In this article, we consider some previous attempts to understand the vulnerability of minorities in research, and then provide our own account. First we examine the question of the representation of minorities in research. Then we argue that the best understanding of minorities, vulnerability, and research will begin with a broad understanding of the risk of individual members of minority groups to poor health outcomes. We offer a typology of vulnerability to help with this task. Finally, we show how researchers should be guided by this broad analysis in the design and execution of their research. PMID:24134375

  3. Some More Vulnerable to Nicotine Addiction Than Others

    MedlinePLUS

    ... news/fullstory_154877.html Some More Vulnerable to Nicotine Addiction Than Others: Study Finding has implications for ... come into contact with a small amount of nicotine. "When you give people nicotine for the first ...

  4. Vulnerability of Oregon hydrologic landscapes and streamflow to climate change

    EPA Science Inventory

    Hydrologic classification systems can provide a basis for broadscale assessments of the hydrologic functions of landscapes and watersheds and their responses to stressors. Such assessments could be particularly useful in determining hydrologic vulnerability from climate change. ...

  5. Rethinking the Vulnerability of Minority Populations in Research

    PubMed Central

    Lange, Margaret Meek

    2013-01-01

    The Belmont Report, produced in 1979 by a United States government commission, includes minority populations among its list of vulnerable research participants. In this article, we consider some previous attempts to understand the vulnerability of minorities in research, and then provide our own account. First we examine the question of the representation of minorities in research. Then we argue that the best understanding of minorities, vulnerability, and research will begin with a broad understanding of the risk of individual members of minority groups to poor health outcomes. We offer a typology of vulnerability to help with this task. Finally, we show how researchers should be guided by this broad analysis in the design and execution of their research. PMID:24134375

  6. Breast Cancer Survivors Vulnerable for Thyroid Tumors, and Vice Versa

    MedlinePLUS

    ... nlm.nih.gov/medlineplus/news/fullstory_157105.html Breast Cancer Survivors Vulnerable for Thyroid Tumors, and Vice Versa: ... Chicago researchers who reviewed 37 published studies found breast cancer survivors were 1.55 times more likely to ...

  7. Assessing the Vulnerability of Older Americans to Climate Change

    EPA Science Inventory

    This project is comprised of a series of activities – listening sessions, literature reviews, and an expert elicitation research agenda-setting workshop – designed to examine and characterize the vulnerability of older adults to climate change and opportunities for adaptation. ...

  8. Assessing vulnerability to drought: identifying underlying factors across Europe

    NASA Astrophysics Data System (ADS)

    Urquijo, Julia; Gonzalez Tánago, Itziar; Ballesteros, Mario; De Stefano, Lucia

    2015-04-01

    Drought is considered one of the most severe and damaging natural hazards in terms of people and sectors affected and associated losses. Drought is a normal and recurrent climatic phenomenon that occurs worldwide, although its spatial and temporal characteristics vary significantly among climates. In the case of Europe, in the last thirty years, the region has suffered several drought events that have caused estimated economic damages over a €100 billion and have affected almost 20% of its territory and population. In recent years, there has been a growing awareness among experts and authorities of the need to shift from a reactive crisis approach to a drought risk management approach, as well as of the importance of designing and implementing policies, strategies and plans at country and river basin levels to deal with drought. The identification of whom and what is vulnerable to drought is a central aspect of drought risk mitigation and planning and several authors agree that societal vulnerability often determines drought risk more than the actual precipitation shortfalls. The final aim of a drought vulnerability assessment is to identify the underlying sources of drought impact, in order to develop policy options that help to enhance coping capacity and therefore to prevent drought impact. This study identifies and maps factors underlying vulnerability to drought across Europe. The identification of factors influencing vulnerability starts from the analysis of past drought impacts in four European socioeconomic sectors. This analysis, along with an extensive literature review, led to the selection of vulnerability factors that are both relevant and adequate for the European context. Adopting the IPCC model, vulnerability factors were grouped to describe exposure, sensitivity and adaptive capacity. The aggregation of these components has resulted in the mapping of vulnerability to drought across Europe at NUTS02 level. Final results have been compared with data from the European Drought Impact Report Inventory. For specific hotpots vulnerability factors are presented also through spider diagrams in order to allow policy and decision makers to identify underlying sources of vulnerability in the European context. This assessment offers an overall picture at a European level that strives to contribute to enhance the understanding of drought vulnerability across Europe.

  9. The hack attack - Increasing computer system awareness of vulnerability threats

    NASA Technical Reports Server (NTRS)

    Quann, John; Belford, Peter

    1987-01-01

    The paper discusses the issue of electronic vulnerability of computer based systems supporting NASA Goddard Space Flight Center (GSFC) by unauthorized users. To test the security of the system and increase security awareness, NYMA, Inc. employed computer 'hackers' to attempt to infiltrate the system(s) under controlled conditions. Penetration procedures, methods, and descriptions are detailed in the paper. The procedure increased the security consciousness of GSFC management to the electronic vulnerability of the system(s).

  10. Physical vulnerability of reinforced concrete buildings impacted by snow avalanches

    NASA Astrophysics Data System (ADS)

    Bertrand, D.; Naaim, M.; Brun, M.

    2010-07-01

    This paper deals with the assessment of physical vulnerability of civil engineering structures to snow avalanche loadings. In this case, the vulnerability of the element at risk is defined by its damage level expressed on a scale from 0 (no damage) to 1 (total destruction). The vulnerability of a building depends on its structure and flow features (geometry, mechanical properties, type of avalanche, topography, etc.). This makes it difficult to obtain vulnerability relations. Most existing vulnerability relations have been built from field observations. This approach suffers from the scarcity of well documented events. Moreover, the back analysis is based on both rough descriptions of the avalanche and the structure. To overcome this problem, numerical simulations of reinforced concrete structures loaded by snow avalanches are carried out. Numerical simulations allow to study, in controlled conditions, the structure behavior under snow avalanche loading. The structure is modeled in 3-D by the finite element method (FEM). The elasto-plasticity framework is used to represent the mechanical behavior of both materials (concrete and steel bars) and the transient feature of the avalanche loading is taken into account in the simulation. Considering a reference structure, several simulation campaigns are conducted in order to assess its snow avalanches vulnerability. Thus, a damage index is defined and is based on global and local parameters of the structure. The influence of the geometrical features of the structure, the compressive strength of the concrete, the density of steel inside the composite material and the maximum impact pressure on the damage index are studied and analyzed. These simulations allow establishing the vulnerability as a function of the impact pressure and the structure features. The derived vulnerability functions could be used for risk analysis in a snow avalanche context.

  11. Let them eat risk? Wealth, rights and disaster vulnerability.

    PubMed

    Boyce, J K

    2000-09-01

    Disaster-vulnerability reduction is an impure public good: when provided to one it is provided to others, but not equally provided to all. This means that in addition to the question of how much disaster-vulnerability reduction to provide, policymakers face the question of to whom it should be provided. This essay distinguishes between two broad classes of approaches to the latter question, one based on wealth, the other on rights. PMID:11026158

  12. Evaluation Of The Seismic Vulnerability of Fortified Structures

    SciTech Connect

    Baratta, Alessandro; Corbi, Ileana; Coppari, Sandro

    2008-07-08

    In the paper a prompt method to evaluate the seismic vulnerability of an ancient structure has been applied to the seismic vulnerability of the fortified structures in Italy, having as basics the elaboration of rather gross information about the state, the consistency and the history of the considered population of fabrics. The procedure proves to be rather effective and able to produce reliable results, despite the poor initial data.

  13. Vulnerability-attention analysis for space-related activities

    NASA Technical Reports Server (NTRS)

    Ford, Donnie; Hays, Dan; Lee, Sung Yong; Wolfsberger, John

    1988-01-01

    Techniques for representing and analyzing trouble spots in structures and processes are discussed. Identification of vulnerable areas usually depends more on particular and often detailed knowledge than on algorithmic or mathematical procedures. In some cases, machine inference can facilitate the identification. The analysis scheme proposed first establishes the geometry of the process, then marks areas that are conditionally vulnerable. This provides a basis for advice on the kinds of human attention or machine sensing and control that can make the risks tolerable.

  14. Population Evacuation: Assessing Biophysical Risk and Social Vulnerability to Floods

    NASA Astrophysics Data System (ADS)

    Sim, S.; Lee, D. H.

    2014-12-01

    A relatively new topic of environmental hazards research revolves around vulnerability to disasters. These studies focused separately on biophysical and social vulnerability perspectives. Only recently, community-based vulnerability studies have become common because of the recognition that combining social and biophysical components is important and practical (Cutter, et al., 2000; Cutter, et al., 2003; Turner, et al., 2003). Researchers have modeled vulnerability to analyze its spatial variation (Montz, Cross, and Cutter, 2006). This study aimed at developing a technical framework for community-based vulnerability to the specific hazards of floods. Developing a technical framework in this research used a "vulnerability of place" method (Hebb & Mortsch, 2007). The data reduction technique used was Principal Components Analysis (PCA) which allows for each variable to explain part of the vulnerability. The case study was on flooding in the Tennessee River Basin. The initial run with all 46 variables produced 13 components that explained 69.77% of the variance. Because of the relative homogeneity across the county (i.e., land use and soil types most vulnerable to flooding being located away from heavily populated areas) biophysical variables became less important in this region in creating overall risk scores. This is made all the more obvious by the number of social variables (17) compared to the number of biophysical variables (8) in the final components. The lowest risk block groups are located within the cities: central Florence, central, and central Madison. The highest risk block groups are in rural areas covered predominately with pasture and agricultural land or forests. They also lie near or within the 100 year floodplain.

  15. Climate change vulnerability of global hydropower generation

    NASA Astrophysics Data System (ADS)

    Farinosi, F.; De Cian, E.; Sue Wing, I.

    2014-12-01

    This paper explores the vulnerability of global hydropower generation to the variability in seasonal averages as well as changes in extreme conditions of precipitation, surface runoff, and temperature. A statistical model is used to estimate the elasticity of hydroelectricity generation to the historical variation (1962-2010) in precipitation or runoff, while controlling for potential confounding factors and temperature changes. The estimated elasticities, which informs about hydropower sensitivity to meteorological variations, are combined with changes in future exposure around 2050 in different warming scenarios as simulated by an ensemble of GCMs participating in the CMIP5 project (Taylor et al., 2012). We use a panel regression model to estimate the parameters characterizing a reduced-form relationship between hydropower electricity generation at country level, a set of meteorological indicators, and number of other covariates that control for time-invariant country-specific heterogeneity (country effect), unspecified exogenous influences affecting all countries and units (time effects), and other confounding factors such the electricity generation mix. The estimated model shows that total annual runoff has a significant impact on the annual generation from the small and medium-sized units, whereas large-sized units do not appear to be sensitive to the inter-annual variation in runoff. This finding is reasonably explained by the greater buffer effect of reservoir capacity, which sensibly increases the resilience of these plants to inter-annual runoff variability. In medium-sized units an increase in total runoff by 1% increases electricity generation by 0.028%. Small-sized units are more sensitivity to inter-annual variations in runoff, and the same change in total runoff (1%) increases electricity generation by 0.037%. Seasonal temperature has also a significant impact. A 1% increase in spring temperature reduces electricity generation by 1.63%, while a 1% increase in summer temperature reduces electricity generation by 1.58%. While an increased frequency of warm days has a positive coefficient. Including the SPI indicators reduces marginal effects of the inter-annual variation in total runoff from 0.028 to 0.022 for the medium units and from 0.037 to 0.031 for the small units.

  16. Debating space security: Capabilities and vulnerabilities

    NASA Astrophysics Data System (ADS)

    Sankaran, Jaganath

    The U.S. position in the debate on space security has been that (1) space-based systems could be developed and used to obtain decisive warfighting superiority over an adversary, and (2) these space-based systems, because they might give such an inordinate advantage over any adversary, will be attacked. The Russians and Chinese, in contrast, claim to be threatened by U.S. aspirations in space but deny that they pose a serious threat to U.S. space-based systems. They view the development of advanced military space systems by the United States as evidence of a growing gap of military capabilities limited only by technological—not political—constraints. They argue that U.S. missile defense systems operating in coordination with advanced satellite sensors would weaken their nuclear retaliatory potential. This dissertation argues that the positions held by both of these parties are more extreme than warranted. An analytical evaluation quickly narrows the touted capabilities and assumed vulnerabilities of space systems to a much smaller set of concerns that can be addressed by collaboration. Chapter 2: Operationally Responsive Space (ORS): Is 24/7 Warfighter Support Feasible? demonstrates the infeasibility of dramatically increasing U.S. warfighting superiority by using satellites. Chapter 3: What Can be Achieved by Attacking Satellites? makes the case that although U.S. armed forces rely extensively on its satellite infrastructure, that does not immediately make them desirable targets. The functions performed by military satellites are diffused among large constellations with redundancies. Also, some of the functions performed by these satellites can be substituted for by other terrestrial and aerial systems. Chapter 4: The Limits of Chinese Anti-Satellite Missiles demonstrates that anti-satellite (ASAT) intercepts are very complex under realistic conditions and that a potential adversary with space capabilities comparable to China's has very limited capability to use ASATs in a real-world battle scenario. Finally, in order to evaluate the chief concern raised by the Russians and Chinese, chapter 5: Satellites, Missile Defense and Space Security simulates a boost-phase missile defense system cued by the advanced Space Tracking and Surveillance (STSS) sensors. It demonstrates that even under best case assumptions, the STSS sensors are not good enough for the boost-phase missile defense system to successfully intercept and destroy an ICBM. Together, these chapters aim to narrow the contentions in the debate on space security thereby fostering the international colloboration and data sharing needed to ensure safe operations in space.

  17. Multimodal spectroscopy detects features of vulnerable atherosclerotic plaque.

    PubMed

    S?epanovi?, Obrad R; Fitzmaurice, Maryann; Miller, Arnold; Kong, Chae-Ryon; Volynskaya, Zoya; Dasari, Ramachandra R; Kramer, John R; Feld, Michael S

    2011-01-01

    Early detection and treatment of rupture-prone vulnerable atherosclerotic plaques is critical to reducing patient mortality associated with cardiovascular disease. The combination of reflectance, fluorescence, and Raman spectroscopy-termed multimodal spectroscopy (MMS)-provides detailed biochemical information about tissue and can detect vulnerable plaque features: thin fibrous cap (TFC), necrotic core (NC), superficial foam cells (SFC), and thrombus. Ex vivo MMS spectra are collected from 12 patients that underwent carotid endarterectomy or femoral bypass surgery. Data are collected by means of a unitary MMS optical fiber probe and a portable clinical instrument. Blinded histopathological analysis is used to assess the vulnerability of each spectrally evaluated artery lesion. Modeling of the ex vivo MMS spectra produce objective parameters that correlate with the presence of vulnerable plaque features: TFC with fluorescence parameters indicative of collagen presence; NC?SFC with a combination of diffuse reflectance ?-carotene?ceroid absorption and the Raman spectral signature of lipids; and thrombus with its Raman signature. Using these parameters, suspected vulnerable plaques can be detected with a sensitivity of 96% and specificity of 72%. These encouraging results warrant the continued development of MMS as a catheter-based clinical diagnostic technique for early detection of vulnerable plaques. PMID:21280896

  18. Multimodal spectroscopy detects features of vulnerable atherosclerotic plaque

    PubMed Central

    Š?epanovi?, Obrad R.; Fitzmaurice, Maryann; Miller, Arnold; Kong, Chae-Ryon; Volynskaya, Zoya; Dasari, Ramachandra R.; Kramer, John R.; Feld, Michael S.

    2011-01-01

    Early detection and treatment of rupture-prone vulnerable atherosclerotic plaques is critical to reducing patient mortality associated with cardiovascular disease. The combination of reflectance, fluorescence, and Raman spectroscopy—termed multimodal spectroscopy (MMS)—provides detailed biochemical information about tissue and can detect vulnerable plaque features: thin fibrous cap (TFC), necrotic core (NC), superficial foam cells (SFC), and thrombus. Ex vivo MMS spectra are collected from 12 patients that underwent carotid endarterectomy or femoral bypass surgery. Data are collected by means of a unitary MMS optical fiber probe and a portable clinical instrument. Blinded histopathological analysis is used to assess the vulnerability of each spectrally evaluated artery lesion. Modeling of the ex vivo MMS spectra produce objective parameters that correlate with the presence of vulnerable plaque features: TFC with fluorescence parameters indicative of collagen presence; NC?SFC with a combination of diffuse reflectance ?-carotene?ceroid absorption and the Raman spectral signature of lipids; and thrombus with its Raman signature. Using these parameters, suspected vulnerable plaques can be detected with a sensitivity of 96% and specificity of 72%. These encouraging results warrant the continued development of MMS as a catheter-based clinical diagnostic technique for early detection of vulnerable plaques. PMID:21280896

  19. Forest climate change Vulnerability and Adaptation Assessment in Himalayas

    NASA Astrophysics Data System (ADS)

    Chitale, V. S.; Shrestha, H. L.; Agarwal, N. K.; Choudhurya, D.; Gilani, H.; Dhonju, H. K.; Murthy, M. S. R.

    2014-11-01

    Forests offer an important basis for creating and safeguarding more climate-resilient communities over Hindu Kush Himalayan region. The forest ecosystem vulnerability assessment to climate change and developing knowledge base to identify and support relevant adaptation strategies is realized as an urgent need. The multi scale adaptation strategies portray increasing complexity with the increasing levels in terms of data requirements, vulnerability understanding and decision making to choose a particular adaptation strategy. We present here how such complexities could be addressed and adaptation decisions could be either directly supported by open source remote sensing based forestry products or geospatial analysis and modelled products. The forest vulnerability assessment under climate change scenario coupled with increasing forest social dependence was studied using IPCC Landscape scale Vulnerability framework in Chitwan-Annapurna Landscape (CHAL) situated in Nepal. Around twenty layers of geospatial information on climate, forest biophysical and forest social dependence data was used to assess forest vulnerability and associated adaptation needs using self-learning decision tree based approaches. The increase in forest fires, evapotranspiration and reduction in productivity over changing climate scenario was observed. The adaptation measures on enhancing productivity, improving resilience, reducing or avoiding pressure with spatial specificity are identified to support suitable decision making. The study provides spatial analytical framework to evaluate multitude of parameters to understand vulnerabilities and assess scope for alternative adaptation strategies with spatial explicitness.

  20. Multimodal spectroscopy detects features of vulnerable atherosclerotic plaque

    NASA Astrophysics Data System (ADS)

    Š?epanovi?, Obrad R.; Fitzmaurice, Maryann; Miller, Arnold; Kong, Chae-Ryon; Volynskaya, Zoya; Dasari, Ramachandra R.; Kramer, John R.; Feld, Michael S.

    2011-01-01

    Early detection and treatment of rupture-prone vulnerable atherosclerotic plaques is critical to reducing patient mortality associated with cardiovascular disease. The combination of reflectance, fluorescence, and Raman spectroscopy-termed multimodal spectroscopy (MMS)-provides detailed biochemical information about tissue and can detect vulnerable plaque features: thin fibrous cap (TFC), necrotic core (NC), superficial foam cells (SFC), and thrombus. Ex vivo MMS spectra are collected from 12 patients that underwent carotid endarterectomy or femoral bypass surgery. Data are collected by means of a unitary MMS optical fiber probe and a portable clinical instrument. Blinded histopathological analysis is used to assess the vulnerability of each spectrally evaluated artery lesion. Modeling of the ex vivo MMS spectra produce objective parameters that correlate with the presence of vulnerable plaque features: TFC with fluorescence parameters indicative of collagen presence; NC/SFC with a combination of diffuse reflectance ?-carotene/ceroid absorption and the Raman spectral signature of lipids; and thrombus with its Raman signature. Using these parameters, suspected vulnerable plaques can be detected with a sensitivity of 96% and specificity of 72%. These encouraging results warrant the continued development of MMS as a catheter-based clinical diagnostic technique for early detection of vulnerable plaques.

  1. Malware Sandbox Analysis for Secure Observation of Vulnerability Exploitation

    NASA Astrophysics Data System (ADS)

    Yoshioka, Katsunari; Inoue, Daisuke; Eto, Masashi; Hoshizawa, Yuji; Nogawa, Hiroki; Nakao, Koji

    Exploiting vulnerabilities of remote systems is one of the fundamental behaviors of malware that determines their potential hazards. Understanding what kind of propagation tactics each malware uses is essential in incident response because such information directly links with countermeasures such as writing a signature for IDS. Although recently malware sandbox analysis has been studied intensively, little work is done on securely observing the vulnerability exploitation by malware. In this paper, we propose a novel sandbox analysis method for securely observing malware's vulnerability exploitation in a totally isolated environment. In our sandbox, we prepare two victim hosts. We first execute the sample malware on one of these hosts and then let it attack the other host which is running multiple vulnerable services. As a simple realization of the proposed method, we have implemented a sandbox using Nepenthes, a low-interaction honeypot, as the second victim. Because Nepenthes can emulate a variety of vulnerable services, we can efficiently observe the propagation of sample malware. In the experiments, among 382 samples whose scan capabilities are confirmed, 381 samples successfully started exploiting vulnerabilities of the second victim. This indicates the certain level of feasibility of the proposed method.

  2. Latin hypercube approach to estimate uncertainty in ground water vulnerability

    USGS Publications Warehouse

    Gurdak, J.J.; McCray, J.E.; Thyne, G.; Qi, S.L.

    2007-01-01

    A methodology is proposed to quantify prediction uncertainty associated with ground water vulnerability models that were developed through an approach that coupled multivariate logistic regression with a geographic information system (GIS). This method uses Latin hypercube sampling (LHS) to illustrate the propagation of input error and estimate uncertainty associated with the logistic regression predictions of ground water vulnerability. Central to the proposed method is the assumption that prediction uncertainty in ground water vulnerability models is a function of input error propagation from uncertainty in the estimated logistic regression model coefficients (model error) and the values of explanatory variables represented in the GIS (data error). Input probability distributions that represent both model and data error sources of uncertainty were simultaneously sampled using a Latin hypercube approach with logistic regression calculations of probability of elevated nonpoint source contaminants in ground water. The resulting probability distribution represents the prediction intervals and associated uncertainty of the ground water vulnerability predictions. The method is illustrated through a ground water vulnerability assessment of the High Plains regional aquifer. Results of the LHS simulations reveal significant prediction uncertainties that vary spatially across the regional aquifer. Additionally, the proposed method enables a spatial deconstruction of the prediction uncertainty that can lead to improved prediction of ground water vulnerability. ?? 2007 National Ground Water Association.

  3. Seawater intrusion vulnerability indicators for freshwater lenses in strip islands

    NASA Astrophysics Data System (ADS)

    Morgan, L.; Werner, A. D.

    2014-12-01

    Freshwater lenses on small islands have been described as some of the most vulnerable aquifer systems in the world. Yet, little guidance is available regarding methods for rapidly assessing the vulnerability of freshwater lenses to the potential effects of climate change. To address this gap we employ a steady-state analytic modelling approach to develop seawater intrusion (SWI) vulnerability indicator equations. The vulnerability indicator equations quantify the propensity for SWI to occur in strip islands due to both recharge change and sea-level rise (SLR) (incorporating the effect of land surface inundation (LSI)). This work extends that of Werner et al. (2012) who developed SWI vulnerability indicator equations for unconfined and confined continental aquifers, and did not consider LSI. Flux-controlled and head-controlled conceptualisations of freshwater lenses are adopted. Under flux-controlled conditions the water table is able to rise unencumbered by land surface effects. Under head-controlled conditions the head is fixed at the centre of the lens due to, for example, centrally located topographic controls, surface water features or pumping. A number of inferences about SWI vulnerability in freshwater lenses can be made from the analysis: (1) SWI vulnerability indicators for SLR (under flux-controlled conditions) are proportional to lens thickness (or volume) and the rate of LSI and inversely proportional to island width; (2) SWI vulnerability indicators for recharge change (under flux-controlled conditions) are proportional to lens thickness (or volume) and inversely proportional to recharge; (3) SLR has greater impact under head-controlled conditions rather than flux-controlled conditions, whereas the opposite is the case for LSI and recharge change. Example applications to several case studies illustrate use of the method for rapidly ranking lenses according to vulnerability, thereby allowing for prioritisation of areas where further and more detailed SWI investigations may be required. References Werner, A.D., Ward, J.D., Morgan, L.K., Simmons, C.T., Robinson, N.I., Teubner, M.D., 2012. Vulnerability indicators of seawater intrusion. Ground Water 50(1), 48-58. doi:10.1111/j.1745-6584.2011.00817.x.

  4. Coastal vulnerability: climate change and natural hazards perspectives

    NASA Astrophysics Data System (ADS)

    Romieu, E.; Vinchon, C.

    2009-04-01

    Introduction Studying coastal zones as a territorial concept (Integrated coastal zone management) is an essential issue for managers, as they have to consider many different topics (natural hazards, resources management, tourism, climate change…). The recent approach in terms of "coastal vulnerability" studies (since the 90's) is the main tool used nowadays to help them in evaluating impacts of natural hazards on coastal zones, specially considering climate change. This present communication aims to highlight the difficulties in integrating this concept in risk analysis as it is usually practiced in natural hazards sciences. 1) Coastal vulnerability as a recent issue The concept of coastal vulnerability mainly appears in the International panel on climate change works of 1992 (IPCC. 2001), where it is presented as essential for climate change adaptation. The concept has been defined by a common methodology which proposes the assessment of seven indicators, in regards to a sea level rise of 1m in 2100: people affected, people at risk, capital value at loss, land at loss, wetland at loss, potential adaptation costs, people at risk assuming this adaptation. Many national assessments have been implemented (Nicholls, et al. 1995) and a global assessment was proposed for three indicators (Nicholls, et al. 1999). The DINAS-Coast project reuses this methodology to produce the DIVA-tool for coastal managers (Vafeidis, et al. 2004). Besides, many other methodologies for national or regional coastal vulnerability assessments have been developed (review by (UNFCCC. 2008). The use of aggregated vulnerability indicators (including geomorphology, hydrodynamics, climate change…) is widespread: the USGS coastal vulnerability index is used worldwide and was completed by a social vulnerability index (Boruff, et al. 2005). Those index-based methods propose a vulnerability mapping which visualise indicators of erosion, submersion and/or socio economic sensibility in coastal zones. This concept is a great tool for policy makers to help managing their action and taking into account climate change (McFadden, et al. 2006). However, in those approaches, vulnerability is the output itself (cost of effective impacts, geomorphologic impacts…), but is not integrated it in a risk analysis. Furthermore, those studies emerged from a climatic perspective, which leads to consider climate change as a hazard or pressure whereas risk studies commonly consider hazards such as erosion and flooding, where climate change modifies the drivers of the hazard. 2) The natural hazards and socio economic perspectives In order to reduce impacts of natural hazards, decision makers need a complete risk assessment (probability of losses). Past studies on natural risks (landslide, earthquake...) highlighted the pertinence of defining risk as a combination of : (1)hazard occurrence and intensity, (2) exposition and (3)vulnerability of assets and population to this hazard (e.g. Douglas. 2007, Sarewitz, et al. 2003). Following the Renn and Klinke risk assessment frame, high uncertainties associated with coastal risks considering climatic and anthropic change highlights the importance of working on that concept of "vulnerability" (Klinke and Renn. 2002). Past studies on vulnerability assessment showed a frequently mentioned gap between "impact based" and "human based" points of view. It is nowadays a great issue for natural risk sciences. Many research efforts in FP7 projects such as MOVE and ENSURE focus on integrating the different dimensions of vulnerability (Turner, et al. 2003, Birkmann. 2006). Coastal risk studies highlight another issue of concern. We previously detailed the different use of the term "vulnerability" in the coastal context, quite different of the "natural risk's" use. Interaction of social, economic and physical sciences is considered within two french research projects (Vulsaco, Miseeva), in order to identify the vulnerability of a system to flooding or erosion (i.e. its characteristics that create potential harm), and integrate them in a risk assessment. Global change is considered by modifications of hazard, anthropogenic pressure and exposition, in order to point out possible modification of vulnerabilities. 3) Learning from both perspectives Coastal vulnerability in its "end in itself" and climate change dimension is a widespread tool for decision makers but it can be inadequate when vulnerability is a component of risk. This is mainly due to the consideration of climate change as a "hazard", so that coastal vulnerability is seen as the possible adverse impacts of climate change. As a matter of fact, this concept is clearly well considered by managers, who feel deeply concerned by climate change. However, coastal risk managers would gain in considering climate change more like a driver able to modify existing hazards than like the pressure in itself. Using this concept could lead to new perspectives of coastal risk mitigation for decision makers (social vulnerability, risk perception…), learning from other disciplines and sciences thanks to research projects such as MOVE (FP7). Acknowledgements The authors would like to thank the BRGM coastal team for rich discussions and fruitful collaborations in coastal vulnerability studies, more specially Déborah Idier for animating the Vulsaco project and Manuel Garcin for his work on tsunamis in Sri Lanka. They are also grateful to the MISEEVA and MOVE teams, which are doing some great trans-disciplinary work. References Birkmann, J., 2006. Measuring vulnerability to Natural Hazards : towards disaster resilient societies. United Nations University Press. Boruff, B. J., Emrich, C., Cutter, S. L., 2005. Erosion hazard vulnerability of US coastal counties. Journal of Coastal Research. 21, 932-942. Douglas, J., 2007. Physical vulnerability modelling in natural hazard risk assessment. Natural Hazards and Earth System Sciences. 7, 283-288. IPCC, 2001. Climate change 2001 : synthesis report. A contribution of working groups I, II and III to the Third Assesment Report of the Intergovernmental Panel on Climate Change. Klinke, A. and Renn, O., 2002. A new approach to risk evaluation and management : risk based, precaution based and discourse based strategies. Risk Analysis. 22, 1071-1094. McFadden, L., Nicholls, R.J., Penning-Rowsell, E. (Eds.), 2006. Managing coastal vulnerability. Elsevier Science. Nicholls, R. J., Hoozemans, F. M. J., Marchand, M., 1999. Increasing flood risk and wetland losses due to global sea-level rise: regional and global analyses. Global Environmental Change, Part A: Human and Policy Dimensions. 9, S69-S87. Nicholls, R. J., Leatherman, S. P., Volonte, C. R., 1995. Impacts and responses to sea-level rise; qualitative and quantitative assessments; Potential impacts of accelerated sea-level rise on developing countries. Journal of Coastal Research. Special issue 14, 26-43. Sarewitz, D., Pielke, R., Keykhah, M., 2003. Vulnerability and Risk: Some Thoughts from a Political and Policy Perspective. Risk Analysis. 23, 805-810. Turner, B. L.,II, Kasperson, R. E., Matson, P. A., McCarthy, J. J., Corell, R. W., Christensen, L., Eckley, N., Kasperson, J. X., Luers, A., Martello, M. L., Polsky, C., Pulsipher, A., Schiller, A., 2003. A framework for vulnerability analysis in sustainability science. Proceedings of the National Academy of Sciences, USA. 100, 8074-8079. UNFCCC, 2008. Compendium on methods and tools to evaluate impacts of vulnerability and adaptation to climate change. Vafeidis, A., Nicholls, R., McFadden, L., 2004. Developing a database for global vulnerability analysis of coastal zones: The DINAS-COAST project and the DIVA tool.

  5. Defining and Measuring Coastal Vulnerability and Resilience to Natural Hazards

    NASA Astrophysics Data System (ADS)

    Becker, M. K.; Hoagland, P.

    2014-12-01

    Accounting for an estimated 23 percent of the world's population, coastal communities face many types of natural hazards. In particular, they may be vulnerable to the effects of tropical cyclones, flooding due to tsunamis or storm surges, erosion, saltwater intrusion, and subsidence. These coastal hazards are further exacerbated by population growth and climate change. There is a lack of consensus in the literature about what constitutes vulnerability (negative impacts) and resilience (recovery from negative impacts) and how to measure these phenomena. While some important work has focused on the long-term effects of coastal hazards on economic growth, little has been done to understand, in quantitative terms, the extent to which coastal communities may be vulnerable to such hazards and, if so, whether they can be resilient. We surveyed nine indicators of human well-being in order to determine their potential suitability as measures of coastal vulnerability or resilience. Some measures, such as the Gross Domestic Product, the Human Development Index, and the Gini coefficient, comprise economic or distributional indicators of human welfare; others, such as the Social Vulnerability Index, are more complex and difficult to interpret. We selected per capita personal income as the most viable indicator, due largely to its simplicity and its availability over several decades. We used it to examine human community vulnerability and resilience to a specific coastal hazard—significant storm surges from major coastal hurricanes—in several US coastal metropolitan areas. We compiled data on per capita personal income from the US Bureau of Economic Analysis for 15 to 20 years prior and subsequent to four major hurricanes: Hugo, which hit the Charleston, South Carolina, metropolitan area in 1989; Bob, Cape Cod, Massachusetts, in 1991; Andrew, Miami, Florida, in 1992; and Opal, Pensacola, Florida, in 1995. Intervention analysis using linear regression suggests that these coastal areas exhibited the full range of possible combinations of vulnerability and resilience.

  6. Prediction of individualized therapeutic vulnerabilities in cancer from genomic profiles

    PubMed Central

    Aksoy, Bülent Arman; Demir, Emek; Babur, Özgün; Wang, Weiqing; Jing, Xiaohong; Schultz, Nikolaus; Sander, Chris

    2014-01-01

    Motivation: Somatic homozygous deletions of chromosomal regions in cancer, while not necessarily oncogenic, may lead to therapeutic vulnerabilities specific to cancer cells compared with normal cells. A recently reported example is the loss of one of the two isoenzymes in glioblastoma cancer cells such that the use of a specific inhibitor selectively inhibited growth of the cancer cells, which had become fully dependent on the second isoenzyme. We have now made use of the unprecedented conjunction of large-scale cancer genomics profiling of tumor samples in The Cancer Genome Atlas (TCGA) and of tumor-derived cell lines in the Cancer Cell Line Encyclopedia, as well as the availability of integrated pathway information systems, such as Pathway Commons, to systematically search for a comprehensive set of such epistatic vulnerabilities. Results: Based on homozygous deletions affecting metabolic enzymes in 16 TCGA cancer studies and 972 cancer cell lines, we identified 4104 candidate metabolic vulnerabilities present in 1019 tumor samples and 482 cell lines. Up to 44% of these vulnerabilities can be targeted with at least one Food and Drug Administration-approved drug. We suggest focused experiments to test these vulnerabilities and clinical trials based on personalized genomic profiles of those that pass preclinical filters. We conclude that genomic profiling will in the future provide a promising basis for network pharmacology of epistatic vulnerabilities as a promising therapeutic strategy. Availability and implementation: A web-based tool for exploring all vulnerabilities and their details is available at http://cbio.mskcc.org/cancergenomics/statius/ along with supplemental data files. Contact: statius@cbio.mskcc.org Supplementary information: Supplementary data are available at Bioinformatics online. PMID:24665131

  7. Vulnerability to climate change: people, place and exposure to hazard

    NASA Astrophysics Data System (ADS)

    Hutton, C. W.; Kienberger, S.; Amoako Johnson, F.; Allan, A.; Giannini, V.; Allen, R.

    2011-04-01

    The Human Dimension of the Twinning European and South Asian River Basins to Enhance Capacity and Implement Adaptive Management Approaches Project (EC-Project BRAHMATWINN) is aimed at developing socio-economic tools and context for the effective inclusion of the "Human Dimension" or socio-economic vulnerability into the overall assessment of climate risk in the twinned basins of the Upper Brahmaputra River Basin (UBRB), and the Upper Danube River Basin (UDRB) . This work is conducted in the light of stakeholder/actor analysis and the prevailing legal framework. In order to effectively achieve this end, four key research and associated activities were defined: 1. Identifying stakeholders and actors including: implement an approach to ensure a broad spread of appropriate stakeholder input to the assessment of vulnerability undertaken in Asia and Europe within the research activities of the project. 2. Contextualising legal framework: to provide an assessment of the governance framework relating to socio-environmental policy development within the study site administrative areas leading to the specific identification of related policy and legal recommendations. 3. Spatial analysis and mapping of vulnerability: providing a spatial assessment of the variation of vulnerability to pre-determined environmental stressors across the study areas with an additional specific focus on gender. 4. Inclusion of findings with the broader context of the BRAHMATWINN risk of climate change study through scenarios of hazard and vulnerability (subsequent chapters). This study utilises stakeholder inputs to effectively identify and map relative weightings of vulnerability domains, such as health and education in the context of pre-specified hazards such as flood. The process is underpinned by an adaptation of the IPCC (2001) which characterizes Risk as having the components of Hazard (physiographic component) and Vulnerability (socio-economic component).

  8. Assessing Agricultural Vulnerability in India using NDVI Data Products

    NASA Astrophysics Data System (ADS)

    Kaushalya, R.; Praveen Kumar, V.; Shubhasmita, S.

    2014-11-01

    Impact of climate change on Indian rainfed agriculture was assessed using temporal NDVI data products from AVHRR and MODIS. Agricultural vulnerability was analysed using CV of Max NDVI from NOAA-AVHRR (15-day, 8 km) and MODIS-TERRA (16-day, 250 m) NDVI data products from 1982-2012. AVHRR dataset was found suitable for estimating regional vulnerability at state and agro-eco-sub-region (AESR) level while MODIS dataset was suitable for drawing district-level strategy for adaptation and mitigation. Methodology was developed to analyse NDVI variations with spatial pattern of rainfall using 10 X 10 girded data and spatially interpolating it to estimate Standard Precipitation Index. Study indicated large variations in vegetation dynamics across India owing to bio-climate and natural resource base. IPCC framework of vulnerability and exposure was used to identify vulnerable region extending from arid western India to semi-arid and dry sub-humid regions in central India and southern peninsula. This is a major agricultural region in the country with sizable human and livestock population with millions of marginal and small farm holdings. Exposure to climatic variability at local and regional levels have national implications and study indicated that over 122 districts extending over 110 mha was vulnerable to climate change that spread across 26 typical AESR in 11 states in India. Of the 74 mha under agriculture in the region, MODIS dataset indicated 47 mha as agriculturally vulnerable while coarser resolution of AVHRR dataset indicated a conservative estimate of 29 mha. First ever estimates of agricultural vulnerability for India indicates 20.4 to 33.1 % agricultural land under risk from climate change.

  9. A Vulnerability Assessment Approach for Dams of Mississippi

    NASA Astrophysics Data System (ADS)

    Kuszmaul, J. S.; Gunter, B.; McGregor, G.; Holt, R. M.; Pickens, J.; Holtz, T.; Jones, T.; Phillips, P.

    2007-12-01

    As part of a state-wide effort to characterize the vulnerability of Mississippi's dams, we are developing a new set of vulnerability assessment tools. Our vulnerability assessment methods will consider earlier attempts to develop risk indexing methods for dams, but will be designed to be applied to Mississippi's entire database of over 3,700 dams. Unlike earlier efforts to dams, which emphasized hazards posed by the dams, our methods will be designed to consider intrinsic and extrinsic vulnerability, and consider consequences as well. Intrinsic sources of vulnerability consider such factors as the potential for unstable slopes, piping, and spillway inadequacy. Extrinsic sources of vulnerability will include features such as the potential for intentional or unintentional human acts. Other factors that will be included will be the potential for neglect of maintenance of the dam and susceptibility to interference from wildlife. Consequences will be assessed by considering the downstream population and economic resources that may be at risk due to an uncontrolled release of the reservoir. The analysis of these vulnerabilities and consequences is being calculated using a GIS-based database of all of Mississippi's dams along with population distribution, terrain, and economic resources across the state. Conventional methods of analysis of a dam breach or other uncontrolled release will still be necessary, but the extent to which downstream features and population are affected can be more readily identified. This approach facilitates assessment and decision making on a large dam inventory to permit resources within the state to be directed efficiently to dams that merit attention.

  10. Probabilistic seismic vulnerability and risk assessment of stone masonry structures

    NASA Astrophysics Data System (ADS)

    Abo El Ezz, Ahmad

    Earthquakes represent major natural hazards that regularly impact the built environment in seismic prone areas worldwide and cause considerable social and economic losses. The high losses incurred following the past destructive earthquakes promoted the need for assessment of the seismic vulnerability and risk of the existing buildings. Many historic buildings in the old urban centers in Eastern Canada such as Old Quebec City are built of stone masonry and represent un-measurable architectural and cultural heritage. These buildings were built to resist gravity loads only and generally offer poor resistance to lateral seismic loads. Seismic vulnerability assessment of stone masonry buildings is therefore the first necessary step in developing seismic retrofitting and pre-disaster mitigation plans. The objective of this study is to develop a set of probability-based analytical tools for efficient seismic vulnerability and uncertainty analysis of stone masonry buildings. A simplified probabilistic analytical methodology for vulnerability modelling of stone masonry building with systematic treatment of uncertainties throughout the modelling process is developed in the first part of this study. Building capacity curves are developed using a simplified mechanical model. A displacement based procedure is used to develop damage state fragility functions in terms of spectral displacement response based on drift thresholds of stone masonry walls. A simplified probabilistic seismic demand analysis is proposed to capture the combined uncertainty in capacity and demand on fragility functions. In the second part, a robust analytical procedure for the development of seismic hazard compatible fragility and vulnerability functions is proposed. The results are given by sets of seismic hazard compatible vulnerability functions in terms of structure-independent intensity measure (e.g. spectral acceleration) that can be used for seismic risk analysis. The procedure is very efficient for conducting rapid vulnerability assessment of stone masonry buildings. With modification of input structural parameters, it can be adapted and applied to any other building class. A sensitivity analysis of the seismic vulnerability modelling is conducted to quantify the uncertainties associated with each of the input parameters. The proposed methodology was validated for a scenario-based seismic risk assessment of existing buildings in Old Quebec City. The procedure for hazard compatible vulnerability modelling was used to develop seismic fragility functions in terms of spectral acceleration representative of the inventoried buildings. A total of 1220 buildings were considered. The assessment was performed for a scenario event of magnitude 6.2 at distance 15km with a probability of exceedance of 2% in 50 years. The study showed that most of the expected damage is concentrated in the old brick and stone masonry buildings.

  11. A Preliminary Tsunami Vulnerability Analysis for Yenikapi Region in Istanbul

    NASA Astrophysics Data System (ADS)

    Ceren Cankaya, Zeynep; Suzen, Lutfi; Cevdet Yalciner, Ahmet; Kolat, Cagil; Aytore, Betul; Zaytsev, Andrey

    2015-04-01

    One of the main requirements during post disaster recovery operations is to maintain proper transportation and fluent communication at the disaster areas. Ports and harbors are the main transportation hubs which must work with proper performance at all times especially after the disasters. Resilience of coastal utilities after earthquakes and tsunamis have major importance for efficient and proper rescue and recovery operations soon after the disasters. Istanbul is a mega city with its various coastal utilities located at the north coast of the Sea of Marmara. At Yenikapi region of Istanbul, there are critical coastal utilities and vulnerable coastal structures and critical activities occur daily. Fishery ports, commercial ports, small craft harbors, passenger terminals of intercity maritime transportation, water front commercial and/or recreational structures are some of the examples of coastal utilization which are vulnerable against marine disasters. Therefore their vulnerability under tsunami or any other marine hazard to Yenikapi region of Istanbul is an important issue. In this study, a methodology of vulnerability analysis under tsunami attack is proposed with the applications to Yenikapi region. In the study, high resolution (1m) GIS database of Istanbul Metropolitan Municipality (IMM) is used and analyzed by using GIS implementation. The bathymetry and topography database and the vector dataset containing all buildings/structures/infrastructures in the study area are obtained for tsunami numerical modeling for the study area. GIS based tsunami vulnerability assessment is conducted by applying the Multi-criteria Decision Making Analysis (MCDA). The tsunami parameters from deterministically defined worst case scenarios are computed from the simulations using tsunami numerical model NAMI DANCE. The vulnerability parameters in the region due to two different classifications i) vulnerability of buildings/structures and ii) vulnerability of (human) evacuation are defined and scored. The risk level is computed using tsunami intensity (level of flow depth from simulations) and vulnerability (structural and human-based) at each node in Yenikapi. The results are presented at high resolution (1m) and discussed. Acknowledgements: Partial support by EU 603839 ASTARTE Project, UDAP-C-12-14 of AFAD of Turkey, 108Y227 and 113M556 of TUBITAK Turkey, RAPSODI (CONCERT_Dis-021) of CONCERT-Japan Joint Call, 2011K140210 of DPT, Istanbul Metropolitan Municipality, Japan-Turkey Joint Research Project by JICA on earthquakes and tsunamis in Marmara Region by SATREPS are acknowledged.

  12. Defining Resilience and Vulnerability Based on Ontology Engineering Approach

    NASA Astrophysics Data System (ADS)

    Kumazawa, T.; Matsui, T.; Endo, A.

    2014-12-01

    It is necessary to reflect the concepts of resilience and vulnerability into the assessment framework of "Human-Environmental Security", but it is also in difficulty to identify the linkage between both concepts because of the difference of the academic community which has discussed each concept. The authors have been developing the ontology which deals with the sustainability of the social-ecological systems (SESs). Resilience and vulnerability are also the concepts in the target world which this ontology covers. Based on this point, this paper aims at explicating the semantic relationship between the concepts of resilience and vulnerability based on ontology engineering approach. For this purpose, we first examine the definitions of resilience and vulnerability which the existing literatures proposed. Second, we incorporate the definitions in the ontology dealing with sustainability of SESs. Finally, we focus on the "Water-Energy-Food Nexus Index" to assess Human-Environmental Security, and clarify how the concepts of resilience and vulnerability are linked semantically through the concepts included in these index items.

  13. A Heat Vulnerability Index and Adaptation Solutions for Pittsburgh, Pennsylvania.

    PubMed

    Bradford, Kathryn; Abrahams, Leslie; Hegglin, Miriam; Klima, Kelly

    2015-10-01

    With increasing evidence of global warming, many cities have focused attention on response plans to address their populations' vulnerabilities. Despite expected increased frequency and intensity of heat waves, the health impacts of such events in urban areas can be minimized with careful policy and economic investments. We focus on Pittsburgh, Pennsylvania and ask two questions. First, what are the top factors contributing to heat vulnerability and how do these characteristics manifest geospatially throughout Pittsburgh? Second, assuming the City wishes to deploy additional cooling centers, what placement will optimally address the vulnerability of the at risk populations? We use national census data, ArcGIS geospatial modeling, and statistical analysis to determine a range of heat vulnerability indices and optimal cooling center placement. We find that while different studies use different data and statistical calculations, all methods tested locate additional cooling centers at the confluence of the three rivers (Downtown), the northeast side of Pittsburgh (Shadyside/Highland Park), and the southeast side of Pittsburgh (Squirrel Hill). This suggests that for Pittsburgh, a researcher could apply the same factor analysis procedure to compare data sets for different locations and times; factor analyses for heat vulnerability are more robust than previously thought. PMID:26333158

  14. Correlation analysis of different vulnerability metrics on power grids

    NASA Astrophysics Data System (ADS)

    Ouyang, Min; Pan, Zhezhe; Hong, Liu; Zhao, Lijing

    2014-02-01

    Many scholars have used different metrics to quantify power grid vulnerability in the literature, but how correlated these metrics are is an interesting topic. This paper defines vulnerability as the performance drop of a power grid under a disruptive event, and selects six frequently used performance metrics, including efficiency (E), source-demand considered efficiency (SDE), largest component size (LCS), connectivity level (CL), clustering coefficient (CC), and power supply (PS), to respectively quantify power grid vulnerability V under different node or edge failure probabilities fp and then analyzes the correlation of these six vulnerability metrics. Taking the IEEE 300 power grid as an example, the results show that the flow-based metric V, which is equivalent to the important load shed metric in power engineering, has mild correlation with source-demand considered topology-based metrics V and V, but weak correlation with other topology-based metrics VE, V and V, which do not differentiate source-demand nodes. Similar results are also found in other types of failures, other system operation parameters and other power grids. Hence, one should be careful to use topology-based metrics to quantify the real vulnerability of power grids.

  15. Soft Error Vulnerability of Iterative Linear Algebra Methods

    SciTech Connect

    Bronevetsky, G; de Supinski, B

    2007-12-15

    Devices become increasingly vulnerable to soft errors as their feature sizes shrink. Previously, soft errors primarily caused problems for space and high-atmospheric computing applications. Modern architectures now use features so small at sufficiently low voltages that soft errors are becoming significant even at terrestrial altitudes. The soft error vulnerability of iterative linear algebra methods, which many scientific applications use, is a critical aspect of the overall application vulnerability. These methods are often considered invulnerable to many soft errors because they converge from an imprecise solution to a precise one. However, we show that iterative methods can be vulnerable to soft errors, with a high rate of silent data corruptions. We quantify this vulnerability, with algorithms generating up to 8.5% erroneous results when subjected to a single bit-flip. Further, we show that detecting soft errors in an iterative method depends on its detailed convergence properties and requires more complex mechanisms than simply checking the residual. Finally, we explore inexpensive techniques to tolerate soft errors in these methods.

  16. A unified framework for addiction: Vulnerabilities in the decision process

    PubMed Central

    Redish, A. David; Jensen, Steve; Johnson, Adam

    2013-01-01

    The understanding of decision-making systems has come together in recent years to form a unified theory of decision-making in the mammalian brain as arising from multiple, interacting systems (a planning system, a habit system, and a situation-recognition system). This unified decision-making system has multiple potential access points through which it can be driven to make maladaptive choices, particularly choices that entail seeking of certain drugs or behaviors. We identify 10 key vulnerabilities in the system: (1) moving away from homeostasis, (2) changing allostatic set points, (3) euphorigenic “reward-like” signals, (4) overvaluation in the planning system, (5) incorrect search of situation-action-outcome relationships, (6) misclassification of situations, (7) overvaluation in the habit system, (8) a mismatch in the balance of the two decision systems, (9) over-fast discounting processes, and (10) changed learning rates. These vulnerabilities provide a taxonomy of potential problems with decision-making systems. Although each vulnerability can drive an agent to return to the addictive choice, each vulnerability also implies a characteristic symptomology. Different drugs, different behaviors, and different individuals are likely to access different vulnerabilities. This has implications for an individual’s susceptibility to addiction and the transition to addiction, for the potential for relapse, and for the potential for treatment. PMID:18662461

  17. Do topological models provide good information about electricity infrastructure vulnerability?

    NASA Astrophysics Data System (ADS)

    Hines, Paul; Cotilla-Sanchez, Eduardo; Blumsack, Seth

    2010-09-01

    In order to identify the extent to which results from topological graph models are useful for modeling vulnerability in electricity infrastructure, we measure the susceptibility of power networks to random failures and directed attacks using three measures of vulnerability: characteristic path lengths, connectivity loss, and blackout sizes. The first two are purely topological metrics. The blackout size calculation results from a model of cascading failure in power networks. Testing the response of 40 areas within the Eastern U.S. power grid and a standard IEEE test case to a variety of attack/failure vectors indicates that directed attacks result in larger failures using all three vulnerability measures, but the attack-vectors that appear to cause the most damage depend on the measure chosen. While the topological metrics and the power grid model show some similar trends, the vulnerability metrics for individual simulations show only a mild correlation. We conclude that evaluating vulnerability in power networks using purely topological metrics can be misleading.

  18. Assessing groundwater vulnerability to agrichemical contamination in the Midwest US

    USGS Publications Warehouse

    Burkart, M.R.; Kolpin, D.W.; James, D.E.

    1999-01-01

    Agrichemicals (herbicides and nitrate) are significant sources of diffuse pollution to groundwater. Indirect methods are needed to assess the potential for groundwater contamination by diffuse sources because groundwater monitoring is too costly to adequately define the geographic extent of contamination at a regional or national scale. This paper presents examples of the application of statistical, overlay and index, and process-based modeling methods for groundwater vulnerability assessments to a variety of data from the Midwest U.S. The principles for vulnerability assessment include both intrinsic (pedologic, climatologic, and hydrogeologic factors) and specific (contaminant and other anthropogenic factors) vulnerability of a location. Statistical methods use the frequency of contaminant occurrence, contaminant concentration, or contamination probability as a response variable. Statistical assessments are useful for defining the relations among explanatory and response variables whether they define intrinsic or specific vulnerability. Multivariate statistical analyses are useful for ranking variables critical to estimating water quality responses of interest. Overlay and index methods involve intersecting maps of intrinsic and specific vulnerability properties and indexing the variables by applying appropriate weights. Deterministic models use process-based equations to simulate contaminant transport and are distinguished from the other methods in their potential to predict contaminant transport in both space and time. An example of a one-dimensional leaching model linked to a geographic information system (GIS) to define a regional metamodel for contamination in the Midwest is included.

  19. Climate variability and climate change vulnerability and adaptation. Workshop summary

    SciTech Connect

    Bhatti, N.; Cirillo, R.R.; Dixon, R.K.

    1995-12-31

    Representatives from fifteen countries met in Prague, Czech Republic, on September 11-15, 1995, to share results from the analysis of vulnerability and adaptation to global climate change. The workshop focused on the issues of global climate change and its impacts on various sectors of a national economy. The U.N. Framework Convention on Climate Change (FCCC), which has been signed by more than 150 governments worldwide, calls on signatory parties to develop and communicate measures they are implementing to respond to global climate change. An analysis of a country`s vulnerability to changes in the climate helps it identify suitable adaptation measures. These analyses are designed to determine the extent of the impacts of global climate change on sensitive sectors such as agricultural crops, forests, grasslands and livestock, water resources, and coastal areas. Once it is determined how vulnerable a country may be to climate change, it is possible to identify adaptation measures for ameliorating some or all of the effects.The objectives of the vulnerability and adaptation workshop were to: The objectives of the vulnerability and adaptation workshop were to: Provide an opportunity for countries to describe their study results; Encourage countries to learn from the experience of the more complete assessments and adjust their studies accordingly; Identify issues and analyses that require further investigation; and Summarize results and experiences for governmental and intergovernmental organizations.

  20. The influence of transport network vulnerability for maritime ports

    NASA Astrophysics Data System (ADS)

    Ruscă, F.; Roşca, E.; Rusca, A.; Roşca, M.; Burciu, S.

    2015-11-01

    The concepts of reliability and vulnerability are quite important in assessing the ability of transport networks from land to provide continuity in operation tacking in consideration the relation with seaports. Transport infrastructure modernizing and extension according to land use and sustainable development requirements still represents a challenging issue among policy makers, regional/local communities and scientists. The interest for the researches reliability and vulnerability for transport networks who connect maritime ports with interior city's is generate by the natural disasters, the terrorist acts, unconventional war, etc.. Transport network modelling enable the development of mathematical models used in evaluating the reliability and vulnerability. Nodes or link disruption could have an important impact over transport network users. In our paper we investigates the Romanian road network vulnerability related to Danube crossing versus maritime ports (Constanta and Mangalia) and its mitigation by improving network topology. We use Visum software to promote a methodology to assess road transport network vulnerability versus Romanian seaports and we propose some solutions to reduce probability of road transport network to fail.

  1. Urban flood risk mitigation: from vulnerability assessment to resilient city

    NASA Astrophysics Data System (ADS)

    Serre, D.; Barroca, B.

    2009-04-01

    Urban flood risk mitigation: from vulnerability assessment to resilient city Bruno Barroca1, Damien Serre2 1Laboratory of Urban Engineering, Environment and Building (L G U E H) - Université de Marne-la-Vallée - Pôle Ville, 5, Bd Descartes - Bâtiment Lavoisier - 77454 Marne la Vallée Cedex 2 - France 2City of Paris Engineering School, Construction - Environment Department, 15 rue Fénelon, 75010 Paris, France In France, as in Europe and more generally throughout the world, river floods have been increasing in frequency and severity over the last ten years, and there are more instances of rivers bursting their banks, aggravating the impact of the flooding of areas supposedly protected by flood defenses. Despite efforts made to well maintain the flood defense assets, we often observe flood defense failures leading to finally increase flood risk in protected area during major flood events. Furthermore, flood forecasting models, although they benefit continuous improvements, remain partly inaccurate due to uncertainties populated all along data calculation processes. These circumstances obliged stakeholders and the scientific communities to manage flood risk by integrating new concepts like stakes management, vulnerability assessments and more recently urban resilience development. Definitively, the goal is to reduce flood risk by managing of course flood defenses and improving flood forecasting models, but also stakes and vulnerability of flooded areas to achieve urban resilience face to flood events. Vulnerability to flood is essentially concentrated in urban areas. Assessing vulnerability of a city is very difficult. Indeed, urban area is a complex system composed by a sum of technical sub-systems as complex as the urban area itself. Assessing city vulnerability consists in talking into account each sub system vulnerability and integrating all direct and indirect impacts generally depending from city shape and city spatial organization. At this time, although some research activities have been undertaken, there are no specific methods and tools to assess flood vulnerability at the scale of the city. Indeed, by studying literature we can list some vulnerability indicators and a few Geographic Information System (GIS) tools. But generally indicators and GIS are not developed specifically at the city scale: often a regional scale is used. Analyzing vulnerability at this scale needs more accurate and formalized indicators and GIS tools. The second limit of existing GIS is temporal: even if vulnerability could be assessed and localized through GIS, such tools cannot assist city managers in their decision to efficiency recover after a severe flood event. Due to scale and temporal limits, methods and tools available to assess urban vulnerability need large improvements. Talking into account all these considerations and limits, our research is focusing on: • vulnerability indicators design; • recovery scenarios design; • GIS for city vulnerability assessment and recovery scenarios. Dealing with vulnerability indicators, the goal is to design a set of indicators of city sub systems. Sub systems are seen like assets of high value and complex and interdependent infrastructure networks (i.e. power supplies, communications, water, transport etc.). The infrastructure networks are critical for the continuity of economic activities as well as for the people's basic living needs. Their availability is also required for fast and effective recovery after flood disasters. The severity of flood damage therefore largely depends on the degree that both high value assets and critical urban infrastructure are affected, either directly or indirectly. To face the challenge of designing indicators, a functional model of the city system (and sub systems) has to be built to analyze the system response to flood solicitation. Then, a coherent and an efficient set of vulnerability of indicators could be built up. With such methods city stakeholders will be informed on how and how much their systems are vulnerable. It is a first level of information that has to be completed to become a real decision making tool. Indeed, we have seen that major floods cause almost always failures in the flood defense system. So potentially the city could face a flood event and managers recovery works. Knowing the vulnerability of the city, direct and indirect impacts, how can managers optimize recovery actions? Our research will focus first on proposing recovery scenarios based on the city system and second on vulnerability indicators to first limit damages during floods and to speed up recovery actions. At last, a GIS will be developed to assist stakeholders to take spatial measures to reduce city system weakness before a flood event and to help them to decide on how to optimize recovery actions after a flood event. Dealing with these two temporal scales will allow obtaining more flood resilient cities.

  2. Vulnerability of coastal livelihoods to shrimp farming: Insights from Mozambique.

    PubMed

    Blythe, Jessica; Flaherty, Mark; Murray, Grant

    2015-05-01

    Millions of people around the world depend on shrimp aquaculture for their livelihoods. Yet, the phenomenal growth of shrimp farming has often given rise to considerable environmental and social damage. This article examines the impacts of commercial, export-oriented shrimp aquaculture on local livelihood vulnerability by comparing the exposure, sensitivity, and adaptive capacity of shrimp farm employees with non-farm employees in rural Mozambique. Exposure to stressors was similar between the two groups. Shrimp farm employees had higher assets and higher adaptive capacity than non-farm employees. However, because their income is heavily dependent on a single commodity, shrimp farm employees were highly susceptible to the boom crop nature of intensive shrimp farming. The implications for aquaculture policy and vulnerability research are discussed. The article argues that coastal vulnerability is dynamic, variable, and influenced by multiple processes operating at multiple scales. PMID:25391555

  3. Assessing and managing freshwater ecosystems vulnerable to global change

    USGS Publications Warehouse

    Angeler, David G.; Allen, Craig R.; Birge, Hannah E.; Drakare, Stina; McKie, Brendan G.; Johnson, Richard K.

    2014-01-01

    Freshwater ecosystems are important for global biodiversity and provide essential ecosystem services. There is consensus in the scientific literature that freshwater ecosystems are vulnerable to the impacts of environmental change, which may trigger irreversible regime shifts upon which biodiversity and ecosystem services may be lost. There are profound uncertainties regarding the management and assessment of the vulnerability of freshwater ecosystems to environmental change. Quantitative approaches are needed to reduce this uncertainty. We describe available statistical and modeling approaches along with case studies that demonstrate how resilience theory can be applied to aid decision-making in natural resources management. We highlight especially how long-term monitoring efforts combined with ecological theory can provide a novel nexus between ecological impact assessment and management, and the quantification of systemic vulnerability and thus the resilience of ecosystems to environmental change.

  4. Mechanical vulnerability explains size-dependent mortality of reef corals.

    PubMed

    Madin, Joshua S; Baird, Andrew H; Dornelas, Maria; Connolly, Sean R

    2014-08-01

    Understanding life history and demographic variation among species within communities is a central ecological goal. Mortality schedules are especially important in ecosystems where disturbance plays a major role in structuring communities, such as coral reefs. Here, we test whether a trait-based, mechanistic model of mechanical vulnerability in corals can explain mortality schedules. Specifically, we ask whether species that become increasingly vulnerable to hydrodynamic dislodgment as they grow have bathtub-shaped mortality curves, whereas species that remain mechanically stable have decreasing mortality rates with size, as predicted by classical life history theory for reef corals. We find that size-dependent mortality is highly consistent between species with the same growth form and that the shape of size-dependent mortality for each growth form can be explained by mechanical vulnerability. Our findings highlight the feasibility of predicting assemblage-scale mortality patterns on coral reefs with trait-based approaches. PMID:24894390

  5. An holistic approach to beach erosion vulnerability assessment

    NASA Astrophysics Data System (ADS)

    Alexandrakis, George; Poulos, Serafim Ε.

    2014-08-01

    Erosion is a major threat for coasts worldwide, beaches in particular, which constitute one of the most valuable coastal landforms. Vulnerability assessments related to beach erosion may contribute to planning measures to counteract erosion by identifying, quantifying and ranking vulnerability. Herein, we present a new index, the Beach Vulnerability Index (BVI), which combines simplicity in calculations, easily obtainable data and low processing capacity. This approach provides results not only for different beaches, but also for different sectors of the same beach and enables the identification of the relative significance of the processes involved. It functions through the numerical approximation of indicators that correspond to the mechanisms related to the processes that control beach evolution, such as sediment availability, wave climate, beach morhodynamics and sea level change. The BVI is also intended to be used as a managerial tool for beach sustainability, including resilience to climate change impact on beach erosion.

  6. Detecting Network Vulnerabilities Through Graph TheoreticalMethods

    SciTech Connect

    Cesarz, Patrick; Pomann, Gina-Maria; Torre, Luis de la; Villarosa, Greta; Flournoy, Tamara; Pinar, Ali; Meza Juan

    2007-09-30

    Identifying vulnerabilities in power networks is an important problem, as even a small number of vulnerable connections can cause billions of dollars in damage to a network. In this paper, we investigate a graph theoretical formulation for identifying vulnerabilities of a network. We first try to find the most critical components in a network by finding an optimal solution for each possible cutsize constraint for the relaxed version of the inhibiting bisection problem, which aims to find loosely coupled subgraphs with significant demand/supply mismatch. Then we investigate finding critical components by finding a flow assignment that minimizes the maximum among flow assignments on all edges. We also report experiments on IEEE 30, IEEE 118, and WSCC 179 benchmark power networks.

  7. Economic vulnerability of timber resources to forest fires.

    PubMed

    y Silva, Francisco Rodríguez; Molina, Juan Ramón; González-Cabán, Armando; Machuca, Miguel Ángel Herrera

    2012-06-15

    The temporal-spatial planning of activities for a territorial fire management program requires knowing the value of forest ecosystems. In this paper we extend to and apply the economic valuation principle to the concept of economic vulnerability and present a methodology for the economic valuation of the forest production ecosystems. The forest vulnerability is analyzed from criteria intrinsically associated to the forest characterization, and to the potential behavior of surface fires. Integrating a mapping process of fire potential and analytical valuation algorithms facilitates the implementation of fire prevention planning. The availability of cartography of economic vulnerability of the forest ecosystems is fundamental for budget optimization, and to help in the decision making process. PMID:22343614

  8. Vulnerability in Clinical Research with Patients in Pain

    PubMed Central

    Tait, Raymond C.

    2011-01-01

    Some have characterized patients living with intractable pain as a vulnerable population in both clinical and research settings. Labeling the population as vulnerable, however, does not provide clarity regarding the potential risks that they face when they participate in research. Instead, research vulnerability for patients in pain is a function of an interaction between their pain conditions and elements of the research enterprise. Therefore, the identification of potential risks requires consideration not only of characteristics of patients with chronic pain, but also consideration of features of researchers, the quality of institutional oversight, and the medical/social environment within which the research is conducted. This paper provides an analysis of those risks and provides some suggestions as to how the risks might be better managed. PMID:19245603

  9. An holistic approach to beach erosion vulnerability assessment.

    PubMed

    Alexandrakis, George; Poulos, Serafim Ε

    2014-01-01

    Erosion is a major threat for coasts worldwide, beaches in particular, which constitute one of the most valuable coastal landforms. Vulnerability assessments related to beach erosion may contribute to planning measures to counteract erosion by identifying, quantifying and ranking vulnerability. Herein, we present a new index, the Beach Vulnerability Index (BVI), which combines simplicity in calculations, easily obtainable data and low processing capacity. This approach provides results not only for different beaches, but also for different sectors of the same beach and enables the identification of the relative significance of the processes involved. It functions through the numerical approximation of indicators that correspond to the mechanisms related to the processes that control beach evolution, such as sediment availability, wave climate, beach morhodynamics and sea level change. The BVI is also intended to be used as a managerial tool for beach sustainability, including resilience to climate change impact on beach erosion. PMID:25123815

  10. Vulnerability Management for an Enterprise Resource Planning System

    NASA Astrophysics Data System (ADS)

    Goel, Shivani; Kiran, Ravi; Garg, Deepak

    2012-09-01

    Enterprise resource planning (ERP) systems are commonly used in technical educational institutions(TEIs). ERP systems should continue providing services to its users irrespective of the level of failure. There could be many types of failures in the ERP systems. There are different types of measures or characteristics that can be defined for ERP systems to handle the levels of failure. Here in this paper, various types of failure levels are identified along with various characteristics which are concerned with those failures. The relation between all these is summarized. The disruptions causing vulnerabilities in TEIs are identified .A vulnerability management cycle has been suggested along with many commercial and open source vulnerability management tools. The paper also highlights the importance of resiliency in ERP systems in TEIs.

  11. Different gestational ages and changing vulnerability of the premature brain.

    PubMed

    Sannia, Andrea; Natalizia, Anna R; Parodi, Alessandro; Malova, Mariya; Fumagalli, Monica; Rossi, Andrea; Ramenghi, Luca A

    2015-11-01

    In recent decades, there has been a general increase in survival rates of preterm and low birth weight infants, but this overall decrease in perinatal mortality has not been accompanied by a decrease in long-term physical and mental disability. In order to reduce the long-term sequelae of prematurity and to establish preventive measures, it is important to identify risk factors since the main determinant of specific vulnerability to different types of lesions is gestational age. The regional tissue vulnerability at a given gestational age is probably determined by the local metabolic requirements together with specific cell characteristics and their level of maturation. In this article, we discuss the most common neonatal cerebral lesions (cerebellar haemorrhage, germinal matrix intraventricular haemorrhage, periventricular leukomalacia, arterial ischaemic stroke, cerebral vein sinus thrombosis and hypoxic-ischaemic encephalopathy) related to the gestational age-dependent vulnerability of the premature brain. PMID:23968292

  12. Chemical Safety Vulnerability Working Group report. Volume 1

    SciTech Connect

    Not Available

    1994-09-01

    The Chemical Safety Vulnerability (CSV) Working Group was established to identify adverse conditions involving hazardous chemicals at DOE facilities that might result in fires or explosions, release of hazardous chemicals to the environment, or exposure of workers or the public to chemicals. A CSV Review was conducted in 148 facilities at 29 sites. Eight generic vulnerabilities were documented related to: abandoned chemicals and chemical residuals; past chemical spills and ground releases; characterization of legacy chemicals and wastes; disposition of legacy chemicals; storage facilities and conditions; condition of facilities and support systems; unanalyzed and unaddressed hazards; and inventory control and tracking. Weaknesses in five programmatic areas were also identified related to: management commitment and planning; chemical safety management programs; aging facilities that continue to operate; nonoperating facilities awaiting deactivation; and resource allocations. Volume 1 contains the Executive summary; Introduction; Summary of vulnerabilities; Management systems weaknesses; Commendable practices; Summary of management response plan; Conclusions; and a Glossary of chemical terms.

  13. Vulnerability Analysis and Evaluation of Urban Road System in Tianjin

    NASA Astrophysics Data System (ADS)

    Liu, Y. Q.; Wu, X.

    In recent years, with the development of economy, the road construction of our country has entered into a period of rapid growth. The road transportation network has been expanding and the risk of disasters is increasing. In this paper we study the vulnerability of urban road system in Tianjin. After analyzed many risk factors of the urban road system security, including road construction, road traffic and the natural environment, we proposed an evaluation index of vulnerability of urban road system and established the corresponding evaluation index system. Based on the results of analysis and comprehensive evaluation, appropriate improvement measures and suggestions which may reduce the vulnerability of the road system and improve the safety and reliability of the road system are proposed.

  14. Physically based groundwater vulnerability assessment using sensitivity analysis methods.

    PubMed

    Beaujean, Jean; Lemieux, Jean-Michel; Dassargues, Alain; Therrien, René; Brouyère, Serge

    2014-01-01

    A general physically based method is presented to assess the vulnerability of groundwater to external pressures by numerical simulation of groundwater flow. The concept of groundwater vulnerability assessment considered here is based on the calculation of sensitivity coefficients for a user-defined groundwater state for which we propose several physically based indicators. Two sensitivity analysis methods are presented: the sensitivity equation method and the adjoint operator method. We show how careful selection of a method can significantly minimize the computational effort. An illustration of the general methodology is presented for the Herten aquifer analog (Germany). This application to a simple, yet insightful, case demonstrates the potential use of this general and physically based vulnerability assessment method to complex aquifers. PMID:24236887

  15. [Elements of adolescents' individual vulnerability to HIV/AIDS].

    PubMed

    Toledo, Melina Mafra; Takahashi, Renata Ferreira; De-La-Torre-Ugarte-Guanilo, Mónica Cecilia

    2011-01-01

    Adolescence is characterized by experimentation and discovery, the development of autonomy and close search of sexuality. The objective of this study was to identify the scientific evidences of literature on the elements of the individual dimension of adolescents' vulnerability of to the HIV/AIDS. Through the integrative review, in electronic data bases (Cinahl PubMed, Scopus, LILACS, Adolec, Dedalus, Digital Library of Brazilian of Teses and Dissertações (BDTD) and Portal of Thesis of University of São Paulo), works published between 1996 and 2006 were tracked. 41 studies compose the final sample. The most frequent element of individual vulnerability in the studies was the degree and quality of the knowledge on HI V/AIDS. The revision allowed identifying excellent scientific evidences of the individual vulnerability for the planning of the actions of prevention to the infection for the HIV in adolescents. PMID:21755225

  16. Mechanical vulnerability explains size-dependent mortality of reef corals

    PubMed Central

    Madin, Joshua S; Baird, Andrew H; Dornelas, Maria; Connolly, Sean R

    2014-01-01

    Understanding life history and demographic variation among species within communities is a central ecological goal. Mortality schedules are especially important in ecosystems where disturbance plays a major role in structuring communities, such as coral reefs. Here, we test whether a trait-based, mechanistic model of mechanical vulnerability in corals can explain mortality schedules. Specifically, we ask whether species that become increasingly vulnerable to hydrodynamic dislodgment as they grow have bathtub-shaped mortality curves, whereas species that remain mechanically stable have decreasing mortality rates with size, as predicted by classical life history theory for reef corals. We find that size-dependent mortality is highly consistent between species with the same growth form and that the shape of size-dependent mortality for each growth form can be explained by mechanical vulnerability. Our findings highlight the feasibility of predicting assemblage-scale mortality patterns on coral reefs with trait-based approaches. PMID:24894390

  17. Climate volatility deepens poverty vulnerability in developing countries

    NASA Astrophysics Data System (ADS)

    Ahmed, Syud A.; Diffenbaugh, Noah S.; Hertel, Thomas W.

    2009-07-01

    Extreme climate events could influence poverty by affecting agricultural productivity and raising prices of staple foods that are important to poor households in developing countries. With the frequency and intensity of extreme climate events predicted to change in the future, informed policy design and analysis requires an understanding of which countries and groups are going to be most vulnerable to increasing poverty. Using a novel economic-climate analysis framework, we assess the poverty impacts of climate volatility for seven socio-economic groups in 16 developing countries. We find that extremes under present climate volatility increase poverty across our developing country sample—particularly in Bangladesh, Mexico, Indonesia, and Africa—with urban wage earners the most vulnerable group. We also find that global warming exacerbates poverty vulnerability in many nations.

  18. Flood hazard, vulnerability, and risk assessment for human life

    NASA Astrophysics Data System (ADS)

    Pan, T.; Chang, T.; Lai, J.; Hsieh, M.; Tan, Y.; Lin, Y.

    2011-12-01

    Flood risk assessment is an important issue for the countries suffering tropical cyclones and monsoon. Taiwan is located in the hot zone of typhoon tracks in the Western Pacific. There are three to five typhoons landing Taiwan every year. Typhoons and heavy rainfalls often cause inundation disaster rising with the increase of population and the development of social economy. The purpose of this study is to carry out the flood hazard, vulnerability and risk in term of human life. Based on the concept that flood risk is composed by flood hazard and vulnerability, a inundation simulation is performed to evaluate the factors of flood hazard for human life according to base flood (100-year return period). The flood depth, velocity and rising ratio are the three factors of flood hazards. Furthermore, the factors of flood vulnerability are identified in terms of human life that are classified into two main factors, residents and environment. The sub factors related to residents are the density of population and the density of vulnerable people including elders, youngers and disabled persons. The sub factors related to environment include the the number of building floors, the locations of buildings, the and distance to rescue center. The analytic hierarchy process (AHP) is adopted to determine the weights of these factors. The risk matrix is applied to show the risk from low to high based on the evaluation of flood hazards and vulnerabilities. The Tseng-Wen River watershed is selected as the case study because a serious flood was induced by Typhoon Morakot in 2009, which produced a record-breaking rainfall of 2.361mm in 48 hours in the last 50 years. The results of assessing the flood hazard, vulnerability and risk in term of human life could improve the emergency operation for flood disaster to prepare enough relief goods and materials during typhoon landing.

  19. Selective Neuronal Vulnerability to Oxidative Stress in the Brain

    PubMed Central

    Wang, Xinkun; Michaelis, Elias K.

    2010-01-01

    Oxidative stress (OS), caused by the imbalance between the generation and detoxification of reactive oxygen and nitrogen species (ROS/RNS), plays an important role in brain aging, neurodegenerative diseases, and other related adverse conditions, such as ischemia. While ROS/RNS serve as signaling molecules at physiological levels, an excessive amount of these molecules leads to oxidative modification and, therefore, dysfunction of proteins, nucleic acids, and lipids. The response of neurons to this pervasive stress, however, is not uniform in the brain. While many brain neurons can cope with a rise in OS, there are select populations of neurons in the brain that are vulnerable. Because of their selective vulnerability, these neurons are usually the first to exhibit functional decline and cell death during normal aging, or in age-associated neurodegenerative diseases, such as Alzheimer's disease. Understanding the molecular and cellular mechanisms of selective neuronal vulnerability (SNV) to OS is important in the development of future intervention approaches to protect such vulnerable neurons from the stresses of the aging process and the pathological states that lead to neurodegeneration. In this review, the currently known molecular and cellular factors that contribute to SNV to OS are summarized. Included among the major underlying factors are high intrinsic OS, high demand for ROS/RNS-based signaling, low ATP production, mitochondrial dysfunction, and high inflammatory response in vulnerable neurons. The contribution to the selective vulnerability of neurons to OS by other intrinsic or extrinsic factors, such as deficient DNA damage repair, low calcium-buffering capacity, and glutamate excitotoxicity, are also discussed. PMID:20552050

  20. Research on vulnerability assessments of the Huanghe (Yellow River) delta

    NASA Astrophysics Data System (ADS)

    qiao, shuqing; shi, xuefa

    2014-05-01

    Coastal zone located at the juncture of the sea, river and land, and under the influence of both land and ocean (including atmosphere), especially the sea-level rise and human activities, are vulnerable to environment and ecology. At highest risk are coastal zone of South, Southeast and East Asia with dense populations, low elevations and inadequate adaptive capacity. In China, more than 40% of the population live on the 15% of the land in coastal area and more than 70% cities located around the coastal area. The Chinese coastal region, especially river delta area has been experienced erosion, seawater intrusion and decrease in biodiversity under the combined influence of sea-level rise, tectonic subsidence and flooding. Furthermore, some kinds of human activity, such as land use, building, dam construction, reclamation from the sea and waste dumping strengthen the vulnerability of environment and ecosystem in coastal region. The coastal hazards (e.g. coastal erosion, seawater intrusion, land subsidence) and vulnerability of the Huanghe (Yelllow River) delta area are studied during the past several years. A systematic coastal assessment index is built and an evaluation model is developed using the development platform of Visual studio.Net 2005. The assessment index system includes two parts, inherent (sea level rise rate, elevation, morphology, water and sediment discharge, mean tidal range, mean wave height etc) and specific vulnerability index (population density, GDP, land utilization, protection structures etc). The assessment index are determined the weight using Analytic hierarchy process (AHP) method. Based on the research results, we better understand the current status and future change of coastal vulnerability and hazards, discuss the impact of the natural possess and human activities. Furthermore, we provide defending strategies for coastal zone vulnerability and typical coastal hazards.

  1. Ten questions for evolutionary studies of disease vulnerability

    PubMed Central

    Nesse, Randolph M

    2011-01-01

    Many evolutionary applications in medicine rely on well-established methods, such as population genetics, phylogenetic analysis, and observing pathogen evolution. Approaches to evolutionary questions about traits that leave bodies vulnerable to disease are less well developed. Strategies for formulating questions and hypotheses remain unsettled, and methods for testing evolutionary hypotheses are unfamiliar to many in medicine. This article uses recent examples to illustrate successful strategies and some common challenges. Ten questions arise in the course of considering hypotheses about traits that leave bodies vulnerable to disease. Addressing them systematically can help minimize confusion and errors. PMID:25567972

  2. Tsunami Risk and Vulnerability Analysis for the City of Rhodes

    NASA Astrophysics Data System (ADS)

    Okal, E.; Fliouri, E.; Mitsoudis, D.; Synolakis, C. E.

    2012-12-01

    We present a vulnerability and risk analysis of tsunami hazard for the city of Rhodes. The tsunami hazard is assessed through computed values of the maximum inundation and maximum flow depth derived from a probabilistic scenario for a 1000-year time window, which incorporates hundreds of numerical simulations with MOST code. The data needed to identify tsunami vulnerable areas are gathered combining remote sensing techniques and GIS technology with surveyed observations and estimates of population data. Tsunami risk zones are defined on the basis of both estimated maximum inundation and maximum flow depth data and results are presented using GIS.

  3. Intensified tuberculosis case finding amongst vulnerable communities in southern India

    PubMed Central

    Ananthakrishnan, R.; Jacob, A. G.; Das, M.; Isaakidis, P.; Kumar, A. M. V.

    2015-01-01

    India mainly uses passive case finding to detect tuberculosis (TB) patients through the Revised National Tuberculosis Control Programme (RNTCP). An intensified case finding (ICF) intervention was conducted among vulnerable communities in two districts of Karnataka during July–December 2013; 658 sputum smear-positive TB cases were detected. The number of smear-positive cases detected increased by 8.8% relative to the pre-intervention period (July–December 2012) in intervention communities as compared to an 8.6% decrease in communities without the ICF intervention. ICF activities brought TB services closer to vulnerable communities, moderately increasing TB case detection rates. PMID:26767178

  4. Low vulnerability explosives (LOVEX) for mass-use warheads

    SciTech Connect

    Pruneda, C.; Jessop, E.; McGuire, R.

    1990-03-13

    There is an ongoing effort at Lawrence Livermore National Laboratory to develop explosives with a significantly lower vulnerability to battlefield environments (bullets, fragments, sympathetic detonation) than current explosives (TNT and Comp B) without sacrificing performance or increasing costs. The approach taken is to develop a composite explosive which is comprised of inexpensive fillers such as RDX, NaNO{sub 3}, Al and a low modulus binder system. The binder system uses nitroglycerin/triacetin as an energetic plasticizer. This paper discusses the experimental results to date in vulnerability, performance and processing. 7 refs., 8 figs., 6 tabs.

  5. Vulnerability Analysis Considerations for the Transportation of Special Nuclear Material

    SciTech Connect

    Nicholson, Lary G.; Purvis, James W.

    1999-07-21

    The vulnerability analysis methodology developed for fixed nuclear material sites has proven to be extremely effective in assessing associated transportation issues. The basic methods and techniques used are directly applicable to conducting a transportation vulnerability analysis. The purpose of this paper is to illustrate that the same physical protection elements (detection, delay, and response) are present, although the response force plays a dominant role in preventing the theft or sabotage of material. Transportation systems are continuously exposed to the general public whereas the fixed site location by its very nature restricts general public access.

  6. Vulnerabilities of mutant SWI/SNF complexes in cancer

    PubMed Central

    Helming, Katherine C.; Wang, Xiaofeng; Roberts, Charles W. M.

    2014-01-01

    Cancer genome sequencing efforts have revealed the novel theme that chromatin modifiers are frequently mutated across a wide spectrum of cancers. Mutations in genes encoding subunits of SWI/SNF (BAF) chromatin remodeling complexes are particularly prevalent, occurring in 20% of all human cancers. As these are typically loss-of-function mutations and not directly therapeutically targetable, central goals have been to elucidate mechanism and identify vulnerabilities created by these mutations. Here we discuss emerging data that these mutations lead to the formation of aberrant residual SWI/SNF complexes that constitute a specific vulnerability and discuss the potential for exploiting these dependencies in SWI/SNF-mutant cancers. PMID:25203320

  7. Integrating Science and Engineering to Reduce Vulnerability to Climate Extremes

    NASA Astrophysics Data System (ADS)

    Jones, Mari R.; Holland, Greg J.; Done, James M.

    2013-12-01

    How does our built environment make society vulnerable to climate extremes such as flooding? What knowledge is required by engineering designers and risk managers to address the associated risks? How can engineering/scientific approaches be adapted to reduce vulnerability to weather and climate extremes? These were some of the key questions posed during a recent workshop at the National Center for Atmospheric Research (NCAR), which was attended by climate scientists, civil engineering practitioners, and governmental departments. Engineering design encompasses a broad range of applications; to focus discussions, this workshop targeted the specific theme of water resources.

  8. Validating vulnerability functions for buildings exposed to Alpine torrent processes

    NASA Astrophysics Data System (ADS)

    Totschnig, R.; Fuchs, S.

    2012-04-01

    Vulnerability assessment is generally seen as an important component in the framework of risk assessment. Focusing on the physical vulnerability and following a natural science perspective, vulnerability functions can be used to quantify vulnerability by setting up a mathematical relationship between the degree of loss of an element at risk exposed and the corresponding intensity of the hazardous process. The examined elements at risk were defined as those buildings that were firstly located on the torrent fans of individual Austrian test sites and secondly characterised by mixed types of construction composed from brick masonry and concrete, however used for different purposes (private residential and commercial accommodation buildings). The degree of loss was calculated as the ratio between the damage and the reconstruction value of the corresponding building. The damage was quantitatively registered in terms of monetary loss after the event by professional damage appraisers. The reconstruction values were calculated based on an insurance approach using unit prices per m2. The intensity of the process (fluvial sediment transport and debris flow) was proxied for each individual building in terms of deposition height. Additionally, a relative intensity, composed from a ratio between the deposition height and the height of the affected building, was used to compensate the influence of different building heights on the degree of loss at a given process intensity. The determination of the degree of loss as well as the corresponding intensity yields a scatterplot of vulnerability values for each individual building; illustrating both the degree of loss (ordinate) and the process intensity (abscissa). Nonlinear regression approaches in terms of cumulative distribution functions were applied to derive the mathematical relation between process intensities and degrees of loss. The corresponding parameters were estimated by using a sequential quadratic programming algorithm based on a nonlinear least squares estimation. Based on first results published for fluvial sediment transport in torrents, this study pursued the following aims: (1) testing the possibility to merge the data based on different processes or building types to derive an overall vulnerability function for torrent processes; and (2) validating the final functions to show their practical applicability in Alpine areas outside of Austria. The conducted statistical tests confirmed that in case of absolute intensity a pooling of the vulnerability values for fluvial sediment transport and debris flows as well as for the two building types and the calculation of a joint vulnerability function is justifiable. In the case of relative intensity, commercial accommodation buildings showed higher vulnerability values than private residential buildings considering low intensity values of process intensities. Therefore, based on relative intensity, individual vulnerability functions are proposed for private residential and commercial accommodation buildings. Using data from an Italian validation test site, the broader applicability of the proposed vulnerability functions was confirmed.

  9. Our Shared Future: Social Media, Leadership, Vulnerability, and Digital Identity

    ERIC Educational Resources Information Center

    Stoller, Eric

    2013-01-01

    Social media have challenged us in our journey to support our students. Administrators have entered into new web-based conversations with one another and with their students. Personal branding has created a sense of performativity that conflicts with a growing trend towards online vulnerability. Our leaders have increasingly been engaged in…

  10. Development of hazard-compatible building fragility and vulnerability models

    USGS Publications Warehouse

    Karaca, E.; Luco, N.

    2008-01-01

    We present a methodology for transforming the structural and non-structural fragility functions in HAZUS into a format that is compatible with conventional seismic hazard analysis information. The methodology makes use of the building capacity (or pushover) curves and related building parameters provided in HAZUS. Instead of the capacity spectrum method applied in HAZUS, building response is estimated by inelastic response history analysis of corresponding single-degree-of-freedom systems under a large number of earthquake records. Statistics of the building response are used with the damage state definitions from HAZUS to derive fragility models conditioned on spectral acceleration values. Using the developed fragility models for structural and nonstructural building components, with corresponding damage state loss ratios from HAZUS, we also derive building vulnerability models relating spectral acceleration to repair costs. Whereas in HAZUS the structural and nonstructural damage states are treated as if they are independent, our vulnerability models are derived assuming "complete" nonstructural damage whenever the structural damage state is complete. We show the effects of considering this dependence on the final vulnerability models. The use of spectral acceleration (at selected vibration periods) as the ground motion intensity parameter, coupled with the careful treatment of uncertainty, makes the new fragility and vulnerability models compatible with conventional seismic hazard curves and hence useful for extensions to probabilistic damage and loss assessment.

  11. Vulnerabilities of children admitted to a pediatric inpatient care unit?

    PubMed Central

    de Oliveira, Larissa Natacha; Breigeiron, Márcia Koja; Hallmann, Sofia; Witkowski, Maria Carolina

    2014-01-01

    OBJECTIVE: To identify the vulnerabilities of children admitted to a pediatric inpatient unit of a university hospital. METHODS: Cross-sectional, descriptive study from April to September 2013 with36 children aged 30 days to 12 years old, admitted to medical-surgical pediatric inpatient units of a university hospital and their caregivers. Data concerning sociocultural, socioeconomic and clinical context of children and their families were collected by interview with the child caregiver and from patients, records, and analyzed by descriptive statistics. RESULTS: Of the total sample, 97.1% (n=132) of children had at least one type of vulnerability, the majority related to the caregiver's level of education, followed by caregiver's financial situation, health history of the child, caregiver's family situation, use of alcohol, tobacco, and illicit drugs by the caregiver, family's living conditions, caregiver's schooling, and bonding between the caregiver and the child. Only 2.9% (n=4) of the children did not show any criteria to be classified in a category of vulnerability. CONCLUSIONS: Most children were classified has having a social vulnerability. It is imperative to create networks of support between the hospital and the primary healthcare service to promote healthcare practices directed to the needs of the child and family. PMID:25511001

  12. Opening Pathways for Vulnerable Young People in Patagonia

    ERIC Educational Resources Information Center

    Hamilton, Mary Agnes; Hamilton, Stephen F.; Bianchi, Lucia; Bran, Jacqui

    2013-01-01

    New and improved institutions are needed to support the transition to adulthood of vulnerable young people. Existing institutions that should provide that support demonstrate structural lag: they have not adapted to changing circumstances. Action research was conducted in Por un Manana, an employment training program for low-income youth and young…

  13. Validating the soil vulnerability index for a claypan watershed

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Assessment studies of conservation efforts have shown that best management practices were not always implemented in the most vulnerable areas where they are most needed. While complex computer simulation models can be used to identify these areas, resources needed for using such models are beyond re...

  14. CONFU: Configuration Fuzzing Testing Framework for Software Vulnerability Detection

    PubMed Central

    Dai, Huning; Murphy, Christian; Kaiser, Gail

    2010-01-01

    Many software security vulnerabilities only reveal themselves under certain conditions, i.e., particular configurations and inputs together with a certain runtime environment. One approach to detecting these vulnerabilities is fuzz testing. However, typical fuzz testing makes no guarantees regarding the syntactic and semantic validity of the input, or of how much of the input space will be explored. To address these problems, we present a new testing methodology called Configuration Fuzzing. Configuration Fuzzing is a technique whereby the configuration of the running application is mutated at certain execution points, in order to check for vulnerabilities that only arise in certain conditions. As the application runs in the deployment environment, this testing technique continuously fuzzes the configuration and checks “security invariants” that, if violated, indicate a vulnerability. We discuss the approach and introduce a prototype framework called ConFu (CONfiguration FUzzing testing framework) for implementation. We also present the results of case studies that demonstrate the approach’s feasibility and evaluate its performance. PMID:21037923

  15. Early Detection Monitoring for Vulnerable Great Lakes Coastal Ecosystems

    EPA Science Inventory

    Great Lakes harbors/embayments are vulnerable to introduction of aquatic invasive species. Monitoring is needed to inform on new introductions, as well as to track success of prevention programs intended to limit spread. We have completed a pilot field case study in the Duluth-...

  16. Opening Pathways for Vulnerable Young People in Patagonia

    ERIC Educational Resources Information Center

    Hamilton, Mary Agnes; Hamilton, Stephen F.; Bianchi, Lucia; Bran, Jacqui

    2013-01-01

    New and improved institutions are needed to support the transition to adulthood of vulnerable young people. Existing institutions that should provide that support demonstrate structural lag: they have not adapted to changing circumstances. Action research was conducted in Por un Manana, an employment training program for low-income youth and young…

  17. Selective Prevention: Addressing Vulnerability to Problem Drug Use in Europe

    ERIC Educational Resources Information Center

    Burkhart, Gregor; Gyarmathy, V. Anna; Bo, Alessandra

    2011-01-01

    Following the 2003 publication of the European Union (EU) Council Recommendations and the 2005-2008 and 2009-2012 EU Drugs Action Plans, increasing attention has been given in EU member states' drug policies to populations that are vulnerable to problem drug use (PDU). Monitoring data reported to the EMCDDA by designated agencies from 30 countries…

  18. Working Vulnerability: Agency of Caring Children and Children's Rights

    ERIC Educational Resources Information Center

    Wihstutz, Anne

    2011-01-01

    A growing number of empirical studies deal with children's participation in care relationships in the family. Based on a review of empirical findings in the UK and Germany, this article discusses care-giving children in terms of vulnerability and agency. The focus is set on understandings of family life as interdependent and reciprocal…

  19. Regulatory Guide on Conducting a Security Vulnerability Assessment

    SciTech Connect

    Ek, David R.

    2016-01-01

    This document will provide guidelines on conducting a security vulnerability assessment at a facility regulated by the Radiation Protection Centre. The guidelines provide a performance approach assess security effectiveness. The guidelines provide guidance for a review following the objectives outlined in IAEA NSS#11 for Category 1, 2, & 3 sources.

  20. Perceived Vulnerability to Crime, Criminal Victimization Experience, and Television Viewing.

    ERIC Educational Resources Information Center

    Weaver, James; Wakshlag, Jacob

    1986-01-01

    Analysis of the relationship between undergraduate students' television viewing and their perceptions of personal vulnerability to crime reveals strength and direction of such associations are contingent upon viewer's source of criminal victimization experience, type of prime-time television viewed, and contextual nature of perception of personal…

  1. Reflecting on a Difficult Life: Narrative Construction in Vulnerable Adolescents

    ERIC Educational Resources Information Center

    McLean, Kate C.; Wood, Becky; Breen, Andrea V.

    2013-01-01

    We examined narrative processes of identity development as they related to desistance from delinquent behavior in a sample of vulnerable adolescents. Building on a robust theoretical and empirical foundation in the field of narrative identity, we examined processes of meaning-making and agency in relation to desistance. Thirty-one adolescents were…

  2. Autobiographical Memory as a Predictor of Depression Vulnerability in Girls

    ERIC Educational Resources Information Center

    Hipwell, Alison E.; Sapotichne, Brenna; Klostermann, Susan; Battista, Deena; Keenan, Kate

    2011-01-01

    Overgeneral autobiographical memory (AM), the tendency to recall categories of events when asked to provide specific instances from one's life, is purported to be a marker of depression vulnerability that develops in childhood. Although early adolescence is a period of risk for depression onset especially among girls, prospective examination of…

  3. The Linneweil Affair: A Study in Adolescent Vulnerability.

    ERIC Educational Resources Information Center

    Isser, Natalie

    1984-01-01

    Details the case of Elizabeth Linneweil, a Jewish child who was persuaded by her guardians to convert to Catholicism. The motives of the emotionally vulnerable adolescent--desire to conform, to please guardians, and to cement social bonding in the community--are discussed. (JAC)

  4. Emergency presentations by vulnerable road users: implications for injury prevention

    PubMed Central

    Meuleners, L B; Lee, A H; Haworth, C

    2006-01-01

    Most emergency presentations by vulnerable road users were the result of collisions that did not involve a motor vehicle. Many injuries occurred off?road without police attendance. Hence, reliance on official police records would underestimate the magnitude and scope of these injuries. Suggestions to provide a safer road environment are given. PMID:16461413

  5. Emergency presentations by vulnerable road users: implications for injury prevention.

    PubMed

    Meuleners, L B; Lee, A H; Haworth, C

    2006-02-01

    Most emergency presentations by vulnerable road users were the result of collisions that did not involve a motor vehicle. Many injuries occurred off-road without police attendance. Hence, reliance on official police records would underestimate the magnitude and scope of these injuries. Suggestions to provide a safer road environment are given. PMID:16461413

  6. Plants Vulnerability to Nitrogen Depends on Where They Grow

    USGS Multimedia Gallery

    USGS scientists teamed up with researchers from multiple universities and agencies to test plants’ vulnerability to atmospheric nitrogen pollution from agriculture and other human activities. The team, pictured here, analyzed data from more than 15,000 sites across the continental United State...

  7. The Vulnerable Researcher: Some Unanticipated Challenges of Doctoral Fieldwork

    ERIC Educational Resources Information Center

    Ballamingie, Patricia; Johnson, Sherrill

    2011-01-01

    This paper draws explicitly on the field experiences of two doctoral researchers in geography to elucidate some of the challenges and issues related to researcher vulnerability that are especially acute for graduate students. In spite of significant differences in context, both researchers experienced an unanticipated degree of professional…

  8. Autobiographical Memory as a Predictor of Depression Vulnerability in Girls

    ERIC Educational Resources Information Center

    Hipwell, Alison E.; Sapotichne, Brenna; Klostermann, Susan; Battista, Deena; Keenan, Kate

    2011-01-01

    Overgeneral autobiographical memory (AM), the tendency to recall categories of events when asked to provide specific instances from one's life, is purported to be a marker of depression vulnerability that develops in childhood. Although early adolescence is a period of risk for depression onset especially among girls, prospective examination of…

  9. Mapping vulnerability and conservation adaptation strategies under climate change

    NASA Astrophysics Data System (ADS)

    Watson, James E. M.; Iwamura, Takuya; Butt, Nathalie

    2013-11-01

    Identification of spatial gradients in ecosystem vulnerability to global climate change and local stressors is an important step in the formulation and implementation of appropriate countermeasures. Here we build on recent work to map ecoregional exposure to future climate, using an envelope-based gauge of future climate stability--defined as a measure of how similar the future climate of a region will be to the present climate. We incorporate an assessment of each ecoregion's adaptive capacity, based on spatial analysis of its natural integrity--the proportion of intact natural vegetation--to present a measure of global ecosystem vulnerability. The relationship between intactness (adaptive capacity) and stability (exposure) varies widely across ecoregions, with some of the most vulnerable, according to this measure, located in southern and southeastern Asia, western and central Europe, eastern South America and southern Australia. To ensure the applicability of these findings to conservation, we provide a matrix that highlights the potential implications of this vulnerability assessment for adaptation planning and offers a spatially explicit management guide.

  10. 6 CFR 27.400 - Chemical-terrorism vulnerability information.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... record contains Chemical-terrorism Vulnerability Information controlled by 6 CFR 27.400. Do not disclose to persons without a “need to know” in accordance with 6 CFR 27.400(e). Unauthorized release may... shall be treated as classified information in accordance with 6 CFR 27.400(h) and (i). (4) Other...

  11. 6 CFR 27.400 - Chemical-terrorism vulnerability information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... record contains Chemical-terrorism Vulnerability Information controlled by 6 CFR 27.400. Do not disclose to persons without a “need to know” in accordance with 6 CFR 27.400(e). Unauthorized release may... shall be treated as classified information in accordance with 6 CFR 27.400(h) and (i). (4) Other...

  12. 6 CFR 27.400 - Chemical-terrorism vulnerability information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... record contains Chemical-terrorism Vulnerability Information controlled by 6 CFR 27.400. Do not disclose to persons without a “need to know” in accordance with 6 CFR 27.400(e). Unauthorized release may... shall be treated as classified information in accordance with 6 CFR 27.400(h) and (i). (4) Other...

  13. 6 CFR 27.215 - Security vulnerability assessments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Security vulnerability assessments. 27.215 Section 27.215 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.215 Security...

  14. 6 CFR 27.400 - Chemical-terrorism vulnerability information.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... record contains Chemical-terrorism Vulnerability Information controlled by 6 CFR 27.400. Do not disclose to persons without a “need to know” in accordance with 6 CFR 27.400(e). Unauthorized release may... shall be treated as classified information in accordance with 6 CFR 27.400(h) and (i). (4) Other...

  15. 6 CFR 27.400 - Chemical-terrorism vulnerability information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... record contains Chemical-terrorism Vulnerability Information controlled by 6 CFR 27.400. Do not disclose to persons without a “need to know” in accordance with 6 CFR 27.400(e). Unauthorized release may... shall be treated as classified information in accordance with 6 CFR 27.400(h) and (i). (4) Other...

  16. Childhood Cancer and Vulnerability for Significant Academic Underachievement.

    ERIC Educational Resources Information Center

    Ott, Jeanne S.; And Others

    1982-01-01

    Learning difficulties related to childhood cancer were examined by comparison of 22 oncology patients and 22 children (6 to 17 years old) referred for psychiatric/psychological evaluation. Findings demonstrated, among children undergoing treatment of cancer, some academic vulnerabilities for which psychosocial aspects may not fully account.…

  17. Our Shared Future: Social Media, Leadership, Vulnerability, and Digital Identity

    ERIC Educational Resources Information Center

    Stoller, Eric

    2013-01-01

    Social media have challenged us in our journey to support our students. Administrators have entered into new web-based conversations with one another and with their students. Personal branding has created a sense of performativity that conflicts with a growing trend towards online vulnerability. Our leaders have increasingly been engaged in…

  18. REGIONAL VULNERABILITY ASSESSMENT: CREATING A CONTEXT FOR EVALUATING STREAM ACIDIFICATION

    EPA Science Inventory

    USEPA's Regional Vulnerability Assessment (ReVA) program is designed to identify ecosystems that are likely to vary beyond the range of natural variability and thereby experience reduced ecological integrity as a result of natural and human-induced stressors. ReVA makes use of r...

  19. International Student-Workers in Australia: A New Vulnerable Workforce

    ERIC Educational Resources Information Center

    Nyland, Chris; Forbes-Mewett, Helen; Marginson, Simon; Ramia, Gaby; Sawir, Erlenawati; Smith, Sharon

    2009-01-01

    In the period immediately preceding the 2007 Australian election, much attention was accorded to the impact of the nation's labour laws on vulnerable employees. This debate centred on specific groups including women, youth, migrants and workers on individual employment contracts. International students, by contrast, were ignored in the debate.…

  20. Extreme seismicity and disaster risks: Hazard versus vulnerability (Invited)

    NASA Astrophysics Data System (ADS)

    Ismail-Zadeh, A.

    2013-12-01

    Although the extreme nature of earthquakes has been known for millennia due to the resultant devastation from many of them, the vulnerability of our civilization to extreme seismic events is still growing. It is partly because of the increase in the number of high-risk objects and clustering of populations and infrastructure in the areas prone to seismic hazards. Today an earthquake may affect several hundreds thousand lives and cause significant damage up to hundred billion dollars; it can trigger an ecological catastrophe if occurs in close vicinity to a nuclear power plant. Two types of extreme natural events can be distinguished: (i) large magnitude low probability events, and (ii) the events leading to disasters. Although the first-type events may affect earthquake-prone countries directly or indirectly (as tsunamis, landslides etc.), the second-type events occur mainly in economically less-developed countries where the vulnerability is high and the resilience is low. Although earthquake hazards cannot be reduced, vulnerability to extreme events can be diminished by monitoring human systems and by relevant laws preventing an increase in vulnerability. Significant new knowledge should be gained on extreme seismicity through observations, monitoring, analysis, modeling, comprehensive hazard assessment, prediction, and interpretations to assist in disaster risk analysis. The advanced disaster risk communication skill should be developed to link scientists, emergency management authorities, and the public. Natural, social, economic, and political reasons leading to disasters due to earthquakes will be discussed.

  1. Critiquing War in the Classroom: Professor Positionality, Vulnerability, and Possibility

    ERIC Educational Resources Information Center

    Taber, Nancy

    2014-01-01

    This article describes an analytic autoethnographical research study focusing on my experiences developing, delivering, and evaluating course content critiquing war from a feminist anti-militarist perspective as a pre-tenured faculty member. Themes include: professional vulnerability, student resistance, pedagogical possibility, and scholarly…

  2. Critiquing War in the Classroom: Professor Positionality, Vulnerability, and Possibility

    ERIC Educational Resources Information Center

    Taber, Nancy

    2014-01-01

    This article describes an analytic autoethnographical research study focusing on my experiences developing, delivering, and evaluating course content critiquing war from a feminist anti-militarist perspective as a pre-tenured faculty member. Themes include: professional vulnerability, student resistance, pedagogical possibility, and scholarly…

  3. Vulnerability to shocks in the global seafood trade network

    NASA Astrophysics Data System (ADS)

    Gephart, Jessica A.; Rovenskaya, Elena; Dieckmann, Ulf; Pace, Michael L.; Brännström, Åke

    2016-03-01

    Trade can allow countries to overcome local or regional losses (shocks) to their food supply, but reliance on international food trade also exposes countries to risks from external perturbations. Countries that are nutritionally or economically dependent on international trade of a commodity may be adversely affected by such shocks. While exposure to shocks has been studied in financial markets, communication networks, and some infrastructure systems, it has received less attention in food-trade networks. Here, we develop a forward shock-propagation model to quantify how trade flows are redistributed under a range of shock scenarios and assess the food-security outcomes by comparing changes in national fish supplies to indices of each country’s nutritional fish dependency. Shock propagation and distribution among regions are modeled on a network of historical bilateral seafood trade data from UN Comtrade using 205 reporting territories grouped into 18 regions. In our model exposure to shocks increases with total imports and the number of import partners. We find that Central and West Africa are the most vulnerable to shocks, with their vulnerability increasing when a willingness-to-pay proxy is included. These findings suggest that countries can reduce their overall vulnerability to shocks by reducing reliance on imports and diversifying food sources. As international seafood trade grows, identifying these types of potential risks and vulnerabilities is important to build a more resilient food system.

  4. American Indian Adolescent Girls: Vulnerability to Sex Trafficking, Intervention Strategies

    ERIC Educational Resources Information Center

    Pierce, Alexandra

    2012-01-01

    The Minnesota Indian Women's Resource Center offers harm reduction programming to at-risk adolescent American Indian girls, including outreach, case management, advocacy, healthy sexuality education, and support groups. To evaluate program impact, participants are assessed at intake and every 6 months afterward for current vulnerability to…

  5. The vulnerability index calculation for determination of groundwater quality

    SciTech Connect

    Kurtz, D.A.; Parizek, R.R.

    1995-12-01

    Non-point source pollutants, such as pesticides, enter groundwater systems in a variety of means at wide-ranging concentrations. Risks in using groundwater in human consumption vary depending on the amounts of contaminants, the type of groundwater aquifer, and various use factors. We have devised a method of determining the vulnerability of an aquifer towards contamination with the Vulnerability Index. The Index can be used either as a comparative or an absolute index (comparative with a pure water source or aquifer spring or without comparison, assuming no peaks in the compared sample). Data for the calculation is obtained by extraction of a given water sample followed by analysis with a nitrogen/phosphorus detector on gas chromatography. The calculation uses the sum of peak heights as its determination. An additional peak number factor is added to emphasize higher numbers of compounds found in a given sample. Karst aquifers are considered to be highly vulnerable due to the large solution openings in its structure. Examples will be given of Vulnerability Indices taken from springs emanating from karst, intermediate, and diffuse flow aquifers taken at various times of the 1992 sampling year and compared with rainfall during that time. Comparisons will be made of the Index vs. rainfall events and vs. pesticide application data. The risk of using contaminated drinking water sources can be evaluated with the use of this index.

  6. 40 CFR 1400.4 - Vulnerable zone indicator system.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Vulnerable zone indicator system. 1400.4 Section 1400.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY AND DEPARTMENT OF JUSTICE ACCIDENTAL RELEASE PREVENTION REQUIREMENTS; RISK MANAGEMENT PROGRAMS UNDER THE CLEAN AIR ACT SECTION...

  7. 40 CFR 1400.4 - Vulnerable zone indicator system.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Vulnerable zone indicator system. 1400.4 Section 1400.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY AND DEPARTMENT OF JUSTICE ACCIDENTAL RELEASE PREVENTION REQUIREMENTS; RISK MANAGEMENT PROGRAMS UNDER THE CLEAN AIR ACT SECTION...

  8. Drug Prevention with Vulnerable Young People: A Review

    ERIC Educational Resources Information Center

    Roe, Stephen; Becker, Jane

    2005-01-01

    The aim of this study was to carry out a comprehensive and systematic review of the literature on drug-use prevention with vulnerable young people. A search of electronic databases was conducted to find evaluations of prevention programmes targeted at high-risk young people and including illegal drug use as an outcome measure. Sixteen relevant…

  9. Attacker-defender models and road network vulnerability.

    PubMed

    Bell, M G H; Kanturska, U; Schmöcker, J-D; Fonzone, A

    2008-06-13

    The reliability of road networks depends directly on their vulnerability to disruptive incidents, ranging in severity from minor disruptions to terrorist attacks. This paper presents a game theoretic approach to the analysis of road network vulnerability. The approach posits predefined disruption, attack or failure scenarios and then considers how to use the road network so as to minimize the maximum expected loss in the event of one of these scenarios coming to fruition. A mixed route strategy is adopted, meaning that the use of the road network is determined by the worst scenario probabilities. This is equivalent to risk-averse route choice. A solution algorithm suitable for use with standard traffic assignment software is presented, thereby enabling the use of electronic road navigation networks. A variant of this algorithm suitable for risk-averse assignment is developed. A numerical example relating to the central London road network is presented. The results highlight points of vulnerability in the road network. Applications of this form of network vulnerability analysis together with improved solution methods are discussed. PMID:18325875

  10. Assessing the Vulnerability of Older Americans to Climate Change

    EPA Science Inventory

    This project is comprised of a series of activities – listening sessions, literature reviews, and an expert elicitation research agenda-setting workshop – designed to examine and characterize the vulnerability of older adults to climate change and opportunities for adaptation. ...

  11. Selective Prevention: Addressing Vulnerability to Problem Drug Use in Europe

    ERIC Educational Resources Information Center

    Burkhart, Gregor; Gyarmathy, V. Anna; Bo, Alessandra

    2011-01-01

    Following the 2003 publication of the European Union (EU) Council Recommendations and the 2005-2008 and 2009-2012 EU Drugs Action Plans, increasing attention has been given in EU member states' drug policies to populations that are vulnerable to problem drug use (PDU). Monitoring data reported to the EMCDDA by designated agencies from 30 countries…

  12. Early Markers of Vulnerable Language Skill Development in Galactosaemia

    ERIC Educational Resources Information Center

    Lewis, Fiona M.; Coman, David J.; Syrmis, Maryanne

    2014-01-01

    There are no known biomedical or genetic markers to identify which infants with galactosaemia (GAL) are most at risk of poor language skill development, yet pre-linguistic communicative "red flag" behaviours are recognised as early identifiers of heightened vulnerability to impaired language development. We report on pre-linguistic…

  13. Tsunami Vulnerability Assessment of Casablanca - Morocco, Pilot Study

    NASA Astrophysics Data System (ADS)

    Omira, R.; Baptista, M. V.; Miranda, M.; Catita, C.; Toto, E.

    2007-12-01

    In this study we present a preliminary evaluation of the tsunami vulnerability of Casablanca area (Morocco) and the expected inundation from a tsunami generated in the North East Atlantic area in the Gulf of Cadiz using a combination of numerical modeling and GIS tools. The study area is the intensively occupied area of the Casablanca Harbor, a location that may be considered as one of the most vulnerable areas to tsunami hazard, along Morocco Atlantic coast, due to its location close to the source of moderate and strong magnitude earthquakes, the extension of low flat areas close to the sea and the existence of dwellings characterized by unstructured constructions. To study vulnerability and inundation we considered geomorphologic and artificial elements as well as the existence of defensive constructions. The inundation zone was divided in for sub-zones according to their height above sea level; the buildings were classed according to: building material, number of floors, conditions of foundation soil. The study area presents a large variety of constructions:1 storey buildings of 2- 2.5 m height, houses and stores of the ancient medina and some modern buildings. The results are presented, using GIS and show a preliminary "picture" of built stock behaviour in case of tsunami for Casablanca. The results clearly demonstrate that the vulnerability to tsunami impact is not uniform within the inundation zone. This work was developed in the framework of NEAREST and TRANSFER projects, EU.

  14. Unipolar Depression, Life Context Vulnerabilities, and Drinking to Cope

    ERIC Educational Resources Information Center

    Holahan, Charles J.; Moos, Rudolf H.; Holahan, Carole K.; Cronkite, Ruth C.; Randall, Patrick K.

    2004-01-01

    This study followed baseline samples of 424 unipolar depressed patients and 424 community controls across 10 years to investigate the association between depression and alcohol-related coping and to examine how life context vulnerabilities underlie the risk for depressed individuals to rely on drinking to cope. Findings supported all hypotheses.…

  15. AN OVERVIEW OF EPA'S REGIONAL VULNERABILITY ASSESSMENT (REVA) PROGRAM

    EPA Science Inventory

    Regional Vulnerability Assessment (ReVA) is a, approach to place-based ecological risk assessment that is currently under development by ORD. The pilot assessment will be done for the Mid-Atlantic region and builds on data collected for EMAP. ReVA is being developed to identify t...

  16. Intergenerational Transmission of Sexual Victimization Vulnerability as Mediated via Parenting

    ERIC Educational Resources Information Center

    Testa, Maria; Hoffman, Joseph H.; Livingston, Jennifer A.

    2011-01-01

    Objectives: Previous research suggests that women's early sexual victimization experiences may influence their parenting behaviors and increase the vulnerability of their children to being sexually victimized. The current study considered whether mother's sexual victimization experiences, in childhood and after age 14, were associated with the…

  17. Psychological Distress and Mortality: Are Women More Vulnerable?

    ERIC Educational Resources Information Center

    Ferraro, Kenneth F.; Nuriddin, Tariqah A.

    2006-01-01

    Does psychological distress increase mortality risk? If it does, are women more vulnerable than men to the effect of distress on mortality? Drawing from cumulative disadvantage theory, these questions are addressed with data from a 20-year follow-up of a national sample of adults ages 25-74. Event history analyses were performed to examine…

  18. Linking degradation status with ecosystem vulnerability to environmental change

    USGS Publications Warehouse

    Angeler, David G.; Baho, Didier L.; Allen, Craig R.; Johnson, Richard K.

    2015-01-01

    Environmental change can cause regime shifts in ecosystems, potentially threatening ecosystem services. It is unclear if the degradation status of ecosystems correlates with their vulnerability to environmental change, and thus the risk of future regime shifts. We assessed resilience in acidified (degraded) and circumneutral (undegraded) lakes with long-term data (1988–2012), using time series modeling. We identified temporal frequencies in invertebrate assemblages, which identifies groups of species whose population dynamics vary at particular temporal scales. We also assessed species with stochastic dynamics, those whose population dynamics vary irregularly and unpredictably over time. We determined the distribution of functional feeding groups of invertebrates within and across the temporal scales identified, and in those species with stochastic dynamics, and assessed attributes hypothesized to contribute to resilience. Three patterns of temporal dynamics, consistent across study lakes, were identified in the invertebrates. The first pattern was one of monotonic change associated with changing abiotic lake conditions. The second and third patterns appeared unrelated to the environmental changes we monitored. Acidified and the circumneutral lakes shared similar levels and patterns of functional richness, evenness, diversity, and redundancy for species within and across the observed temporal scales and for stochastic species groups. These similar resilience characteristics suggest that both lake types did not differ in vulnerability to the environmental changes observed here. Although both lake types appeared equally vulnerable in this study, our approach demonstrates how assessing systemic vulnerability by quantifying ecological resilience can help address uncertainty in predicting ecosystem responses to environmental change across ecosystems.

  19. Cognitive Vulnerability to Depression in Canadian and Chinese Adolescents

    ERIC Educational Resources Information Center

    Auerbach, Randy P.; Eberhart, Nicole K.; Abela, John R. Z.

    2010-01-01

    The goal of the current study was to compare diathesis-stress and transactional models of cognitive vulnerability to depression in samples of Canadian (n = 118) and Chinese (n = 405) adolescents. We utilized a six-month multi-wave, longitudinal design in order to examine whether (a) perceived control moderated the association between the…

  20. Spatial vulnerability of Australian urban populations to extreme heat events

    NASA Astrophysics Data System (ADS)

    Loughnan, Margaret; Tapper, Nigel; Phan, Thu; Lynch, Kellie; McInnes, Judith

    2013-04-01

    Extreme heat events pose a risk to the health of all individuals, especially the elderly and the chronically ill, and are associated with an increased demand for healthcare services. In order to address this problem, policy makers' need information about temperatures above which mortality and morbidity of the exposed population is likely to increase, where the vulnerable groups in the community are located, and how the risks from extreme heat events are likely to change in the future. This study identified threshold temperatures for all Australian capital cities, developed a spatial index of population vulnerability, and used climate model output to predict changes in the number of days exceeding temperature thresholds in the future, as well as changes in risk related to changes in urban density and an ageing population. The study has shown that daily maximum and minimum temperatures from the Bureau of Meteorology forecasts can be used to calculate temperature thresholds for heat alert days. The key risk factors related to adverse health outcomes were found to be areas with intense urban heat islands, areas with higher proportions of older people, and areas with ethnic communities. Maps of spatial vulnerability have been developed to provide information to assist emergency managers, healthcare professionals, and ancillary services develop heatwave preparedness plans at a local scale that target vulnerable groups and address heat-related health risks. The numbers of days exceeding current heat thresholds are predicted to increase over the next 20 to 40 years in all Australian capital cities.

  1. A physical approach on flood risk vulnerability of buildings

    NASA Astrophysics Data System (ADS)

    Mazzorana, B.; Simoni, S.; Scherer, C.; Gems, B.; Fuchs, S.; Keiler, M.

    2014-09-01

    The design of efficient hydrological risk mitigation strategies and their subsequent implementation relies on a careful vulnerability analysis of the elements exposed. Recently, extensive research efforts were undertaken to develop and refine empirical relationships linking the structural vulnerability of buildings to the impact forces of the hazard processes. These empirical vulnerability functions allow estimating the expected direct losses as a result of the hazard scenario based on spatially explicit representation of the process patterns and the elements at risk classified into defined typological categories. However, due to the underlying empiricism of such vulnerability functions, the physics of the damage-generating mechanisms for a well-defined element at risk with its peculiar geometry and structural characteristics remain unveiled, and, as such, the applicability of the empirical approach for planning hazard-proof residential buildings is limited. Therefore, we propose a conceptual assessment scheme to close this gap. This assessment scheme encompasses distinct analytical steps: modelling (a) the process intensity, (b) the impact on the element at risk exposed and (c) the physical response of the building envelope. Furthermore, these results provide the input data for the subsequent damage evaluation and economic damage valuation. This dynamic assessment supports all relevant planning activities with respect to a minimisation of losses, and can be implemented in the operational risk assessment procedure.

  2. A physical approach on flood risk vulnerability of buildings

    NASA Astrophysics Data System (ADS)

    Mazzorana, B.; Simoni, S.; Scherer, C.; Gems, B.; Fuchs, S.; Keiler, M.

    2014-02-01

    The design of efficient hydrological risk mitigation strategies and their subsequent implementation relies on a careful vulnerability analysis of the elements exposed. Recently, extensive research efforts were undertaken to develop and refine empirical relationships linking the structural vulnerability of buildings to the impact forces of the hazard processes. These empirical vulnerability functions allow estimating the expected direct losses as a result of the hazard scenario based on spatially explicit representation of the process patterns and the elements at risk classified into defined typological categories. However, due to the underlying empiricism of such vulnerability functions, the physics of the damage generating mechanisms for a well-defined element at risk with its peculiar geometry and structural characteristics remain unveiled, and, as such, the applicability of the empirical approach for planning hazard-proof residential buildings is limited. Therefore, we propose a conceptual assessment scheme to close this gap. This assessment scheme encompasses distinct analytical steps: modelling (a) the process intensity, (b) the impact on the element at risk exposed and (c) the physical response of the building envelope. Furthermore, these results provide the input data for the subsequent damage evaluation and economic damage valuation. This dynamic assessment supports all relevant planning activities with respect to a minimisation of losses, and can be implemented in the operational risk assessment procedure.

  3. Early Markers of Vulnerable Language Skill Development in Galactosaemia

    ERIC Educational Resources Information Center

    Lewis, Fiona M.; Coman, David J.; Syrmis, Maryanne

    2014-01-01

    There are no known biomedical or genetic markers to identify which infants with galactosaemia (GAL) are most at risk of poor language skill development, yet pre-linguistic communicative "red flag" behaviours are recognised as early identifiers of heightened vulnerability to impaired language development. We report on pre-linguistic…

  4. International Student-Workers in Australia: A New Vulnerable Workforce

    ERIC Educational Resources Information Center

    Nyland, Chris; Forbes-Mewett, Helen; Marginson, Simon; Ramia, Gaby; Sawir, Erlenawati; Smith, Sharon

    2009-01-01

    In the period immediately preceding the 2007 Australian election, much attention was accorded to the impact of the nation's labour laws on vulnerable employees. This debate centred on specific groups including women, youth, migrants and workers on individual employment contracts. International students, by contrast, were ignored in the debate.…

  5. Cross comparison of five popular groundwater pollution vulnerability index approaches

    NASA Astrophysics Data System (ADS)

    Brindha, K.; Elango, L.

    2015-05-01

    Identification of a suitable overlay and index method to map vulnerable zones for pollution in weathered rock aquifers was carried out in this study. DRASTIC and four models derived from it, namely Pesticide DRASTIC, modified DRASTIC, modified Pesticide DRASTIC and Susceptibility Index (SI) were compared by applying them to a weathered rock aquifer in southern India. The results were validated with the measured geochemical data. This study also introduces the use of temporal variation in the groundwater level and nitrate concentration in groundwater as input and for validation respectively to obtain more reliable and meaningful results. Sensitivity analysis of the vulnerability index maps highlight the importance of one parameter over another for a given hydrogeological setting, which will help to plan the field investigations based on the most or the least influential parameter. It is recommended to use modified Pesticide DRASTIC for weathered rock regions with irrigation practises and shallow aquifers (<20 m bgl). The crucial input due to land use should not be neglected and to be considered in any hydrogeological setting. It is better to estimate the specific vulnerability wherever possible rather than the intrinsic vulnerability as overlay and index methods are more suited for this purpose. It is also necessary to consider the maximum and minimum values of input parameters measured during a normal year in the models used for decision making.

  6. VIRAL TRANSPORT AND FATE MODELS FOR GROUND WATER VULNERABILITY

    EPA Science Inventory

    The purpose of this project is to develop a model to assess the vulnerability of public water systems to pathogens. It is focused on the sources, fate and transport of viruses in aquifer systems in specific hydrologic settings. It's intended to be used by resource managers or r...

  7. Family and social vulnerability: a study with octogenarians.

    PubMed

    Pavarini, Sofia Cristina Iost; Barha, Elizabeth Joan; Mendiondo, Marisa Silvana Zazzetta de; Filizola, Carmen Lucia Alves; Petrilli Filho, José Fernando; Santos, Ariene Angelini Dos

    2009-01-01

    In order to guide the development of dementia-related public policies for the elderly, it is important to identify factors that vary together with the social vulnerability of this population. This study aimed to identify the relationship between the São Paulo Social Vulnerability Index (IPVS) and various indicators of family support for elderly people over 80 years of age, who presented cognitive alterations (N=49). All ethical guidelines were followed. Data were collected at the homes of the elderly people. A large majority of the respondents lived with family members (88%). In half of the cases, the respondents lived with one (41%) or two (9%) other elderly persons. On average, there was one more non-elderly person living in the high vulnerability family context (M = 3.6, sd = 1.70) than in contexts of very low vulnerability (M = 2.4, sd = 1.07), F(2.43) = 3.364, p < 0.05. However, the functionality of the support provided by these family members needs to be verified, in each of these contexts. PMID:19669049

  8. Reflecting on a Difficult Life: Narrative Construction in Vulnerable Adolescents

    ERIC Educational Resources Information Center

    McLean, Kate C.; Wood, Becky; Breen, Andrea V.

    2013-01-01

    We examined narrative processes of identity development as they related to desistance from delinquent behavior in a sample of vulnerable adolescents. Building on a robust theoretical and empirical foundation in the field of narrative identity, we examined processes of meaning-making and agency in relation to desistance. Thirty-one adolescents were…

  9. Dyadic Vulnerability and Risk Profiling for Elder Neglect

    ERIC Educational Resources Information Center

    Fulmer, Terry; Paveza, Gregory; VandeWeerd, Carla; Fairchild, Susan; Guadagno, Lisa; Bolton-Blatt, Marguarette; Norman, Robert

    2005-01-01

    Purpose: Neglect of older adults accounts for 60% to 70% of all elder-mistreatment reports made to adult protective services. The purpose of this article is to report data from research, using a risk-and-vulnerability model, that captures the independent contributions of both the elder and the caregiver as they relate to the outcome of neglect.…

  10. Vulnerability Assessment of Selected Buildings Designated as Shelters: Grenada.

    ERIC Educational Resources Information Center

    Gibbs, Tony

    Educational facilities in the Caribbean often serve as shelters during natural hazards, but they often sustain as much damage as other buildings. This study investigated the physical vulnerability of schools, located in Grenada, to wind forces, torrential rain, and seismic forces in order to provide relevant local agencies with some of the input…

  11. Vulnerability Assessment of Selected Buildings Designated as Shelters: Anguilla.

    ERIC Educational Resources Information Center

    Gibbs, Tony

    Educational facilities in the Caribbean often serve roles as shelters during natural hazards, but they often sustain as much damage as other buildings. This study investigated the physical vulnerability of schools located on Anguilla to wind forces, torrential rain, and seismic forces in order to provide relevant local agencies with some of the…

  12. Vulnerability Assessment of Selected Buildings Designated as Shelters: Dominica.

    ERIC Educational Resources Information Center

    Agency for International Development (IDCA), Washington, DC.

    Educational facilities in the Caribbean often serve roles as shelters during natural hazards, but they often sustain as much damage as other buildings. This study investigated the physical vulnerability of schools located on Dominica to wind forces, torrential rain, and seismic forces in order to provide relevant local agencies with some of the…

  13. Assessing application vulnerability to radiation-induced SEUs in memory

    NASA Technical Reports Server (NTRS)

    Springer, P. L.

    2001-01-01

    One of the goals of the Remote Exploration and Experimentation (REE) project at JPL is to determine how vulnerable applications are to single event upsets (SEUs) when run in low radiation space environments using commercial-off-the-shelf (COTS) components.

  14. Psychological Distress and Mortality: Are Women More Vulnerable?

    ERIC Educational Resources Information Center

    Ferraro, Kenneth F.; Nuriddin, Tariqah A.

    2006-01-01

    Does psychological distress increase mortality risk? If it does, are women more vulnerable than men to the effect of distress on mortality? Drawing from cumulative disadvantage theory, these questions are addressed with data from a 20-year follow-up of a national sample of adults ages 25-74. Event history analyses were performed to examine…

  15. Vulnerability of the US to future sea level rise

    SciTech Connect

    Gornitz, V. . Goddard Inst. for Space Studies); White, T.W.; Cushman, R.M. )

    1991-01-01

    The differential vulnerability of the conterminous United States to future sea level rise from greenhouse climate warming is assessed, using a coastal hazards data base. This data contains information on seven variables relating to inundation and erosion risks. High risk shorelines are characterized by low relief, erodible substrate, subsidence, shoreline retreat, and high wave/tide energies. Very high risk shorelines on the Atlantic Coast (Coastal Vulnerability Index {ge}33.0) include the outer coast of the Delmarva Peninsula, northern Cape Hatteras, and segments of New Jersey, Georgia and South Carolina. Louisiana and sections of Texas are potentially the most vulnerable, due to anomalously high relative sea level rise and erosion, coupled with low elevation and mobile sediments. Although the Pacific Coast is generally the least vulnerable, because of its rugged relief and erosion-resistant substrate, the high geographic variability leads to several exceptions, such as the San Joaquin-Sacramento Delta area, the barrier beaches of Oregon and Washington, and parts of the Puget Sound Lowlands. 31 refs., 2 figs., 3 tabs.

  16. 6 CFR 27.215 - Security vulnerability assessments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Section 27.215 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.215 Security vulnerability assessments. (a) Initial Assessment. If the Assistant Secretary determines that a chemical facility is...

  17. 6 CFR 27.215 - Security vulnerability assessments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Section 27.215 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.215 Security vulnerability assessments. (a) Initial Assessment. If the Assistant Secretary determines that a chemical facility is...

  18. 6 CFR 27.215 - Security vulnerability assessments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Section 27.215 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.215 Security vulnerability assessments. (a) Initial Assessment. If the Assistant Secretary determines that a chemical facility is...

  19. 6 CFR 27.215 - Security vulnerability assessments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Section 27.215 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.215 Security vulnerability assessments. (a) Initial Assessment. If the Assistant Secretary determines that a chemical facility is...

  20. EPA'S REGIONAL VULNERABILITY ASSESSMENT PROGRAM (REVA) DEMONSTRATING RESULTS THROUGH PARTNERSHIPS

    EPA Science Inventory

    EPA's Regional Vulnerability Assessment (ReVA) program, a regional-scale comparative risk research effort, has been under development since 1998 with a pilot study focused on the Mid- Atlantic region. ReVA is part of the interagency Integrated Science for Ecosystem Challenges ini...

  1. Youth Work with Vulnerable Young People. Interchange No. 51.

    ERIC Educational Resources Information Center

    Powney, Janet; Furlong, Andy; Cartmel, Fred; Hall, Stuart

    Research was conducted in Scotland to evaluate the effectiveness of youth work with vulnerable young people, primarily between the ages of 13 and 16. Four complementary methods were adopted: (1) a survey of secondary school students; (2) a series of focus group interviews with young people with experience of youth work; (3) interviews with…

  2. Stressful Segregation Housing and Psychosocial Vulnerability in Prison Suicide Ideators

    ERIC Educational Resources Information Center

    Bonner, Ronald L.

    2006-01-01

    Psychosocially vulnerable prisoners under stressful conditions of confinement are ill prepared to cope and at risk for developing suicide intention. The present study examined the relationships of depression, hopelessness, reasons for living, mental health problem history, suicide attempt lethality history, and stressful segregation housing with…

  3. Vulnerability analysis for a drought Early Warning System

    NASA Astrophysics Data System (ADS)

    Angeluccetti, Irene; Demarchi, Alessandro; Perez, Francesca

    2014-05-01

    Early Warning Systems (EWS) for drought are often based on risk models that do not, or marginally, take into account the vulnerability factor. The multifaceted nature of drought (hydrological, meteorological, and agricultural) is source of coexistence for different ways to measure this phenomenon and its effects. The latter, together with the complexity of impacts generated by this hazard, causes the current underdevelopment of drought EWS compared to other hazards. In Least Developed Countries, where drought events causes the highest numbers of affected people, the importance of correct monitoring and forecasting is considered essential. Existing early warning and monitoring systems for drought produced at different geographic levels, provide only in a few cases an actual spatial model that tries to describe the cause-effect link between where the hazard is detected and where impacts occur. Integrate vulnerability information in such systems would permit to better estimate affected zones and livelihoods, improving the effectiveness of produced hazard-related datasets and maps. In fact, the need of simplification and, in general, of a direct applicability of scientific outputs is still a matter of concern for field experts and early warning products end-users. Even if the surplus of hazard related information produced right after catastrophic events has, in some cases, led to the creation of specific data-sharing platforms, the conveyed meaning and usefulness of each product has not yet been addressed. The present work is an attempt to fill this gap which is still an open issue for the scientific community as well as for the humanitarian aid world. The study aims at conceiving a simplified vulnerability model to embed into an existing EWS for drought, which is based on the monitoring of vegetation phenological parameters and the Standardized Precipitation Index, both produced using free satellite derived datasets. The proposed vulnerability model includes (i) a pure agricultural vulnerability and (ii) a systemic vulnerability. The first considers the agricultural potential of terrains, the diversity of cultivated crops and the percentage of irrigated area as main driving factors. The second vulnerability aspect consists of geographic units in which a set of socio-economic factors are modeled geographically on the basis of the physical accessibility to market centers in one case, and according to a spatial gravity model of market areas in another case. Results of the model applied to a case study (Niger) and evaluated with food insecurity data, are presented.

  4. Vulnerability assessment and risk perception: the case of the Arieş River Middle Basin

    NASA Astrophysics Data System (ADS)

    Ozunu, Al.; Botezan, C.

    2012-04-01

    Vulnerability assessment is influenced by a number of factors, including risk perception. This paper investigates the vulnerability of people living in the middle basin of the Aries river region, a former mining area, to natural and technologic hazards. The mining industry lead to significant environmental changes, which combined with the social problems caused by its decline (high unemployment rate, low income and old age) raised the level of the vulnerability in the area. This case study is unique, as it includes an evaluation of risk perception and its influence on the social vulnerability and resilience of local communities to disasters. Key words: vulnerability assessment, natural hazards, social vulnerability, risk perception

  5. Respect for Human Vulnerability: The Emergence of a New Principle in Bioethics.

    PubMed

    ten Have, Henk

    2015-09-01

    Vulnerability has become a popular though controversial topic in bioethics, notably since 2000. As a result, a common body of knowledge has emerged (1) distinguishing between different types of vulnerability, (2) criticizing the categorization of populations as vulnerable, and (3) questioning the practical implications. It is argued that two perspectives on vulnerability, i.e., the philosophical and political, pose challenges to contemporary bioethics discourse: they re-examine the significance of human agency, the primacy of the individual person, and the negativity of vulnerability. As a phenomenon of globalization, vulnerability can only be properly addressed in a global bioethics that takes the social dimension of human existence seriously. PMID:26160601

  6. Patterns of Freshwater Species Richness, Endemism, and Vulnerability in California.

    PubMed

    Howard, Jeanette K; Klausmeyer, Kirk R; Fesenmyer, Kurt A; Furnish, Joseph; Gardali, Thomas; Grantham, Ted; Katz, Jacob V E; Kupferberg, Sarah; McIntyre, Patrick; Moyle, Peter B; Ode, Peter R; Peek, Ryan; Quiñones, Rebecca M; Rehn, Andrew C; Santos, Nick; Schoenig, Steve; Serpa, Larry; Shedd, Jackson D; Slusark, Joe; Viers, Joshua H; Wright, Amber; Morrison, Scott A

    2015-01-01

    The ranges and abundances of species that depend on freshwater habitats are declining worldwide. Efforts to counteract those trends are often hampered by a lack of information about species distribution and conservation status and are often strongly biased toward a few well-studied groups. We identified the 3,906 vascular plants, macroinvertebrates, and vertebrates native to California, USA, that depend on fresh water for at least one stage of their life history. We evaluated the conservation status for these taxa using existing government and non-governmental organization assessments (e.g., endangered species act, NatureServe), created a spatial database of locality observations or distribution information from ~400 data sources, and mapped patterns of richness, endemism, and vulnerability. Although nearly half of all taxa with conservation status (n = 1,939) are vulnerable to extinction, only 114 (6%) of those vulnerable taxa have a legal mandate for protection in the form of formal inclusion on a state or federal endangered species list. Endemic taxa are at greater risk than non-endemics, with 90% of the 927 endemic taxa vulnerable to extinction. Records with spatial data were available for a total of 2,276 species (61%). The patterns of species richness differ depending on the taxonomic group analyzed, but are similar across taxonomic level. No particular taxonomic group represents an umbrella for all species, but hotspots of high richness for listed species cover 40% of the hotspots for all other species and 58% of the hotspots for vulnerable freshwater species. By mapping freshwater species hotspots we show locations that represent the top priority for conservation action in the state. This study identifies opportunities to fill gaps in the evaluation of conservation status for freshwater taxa in California, to address the lack of occurrence information for nearly 40% of freshwater taxa and nearly 40% of watersheds in the state, and to implement adequate protections for freshwater taxa where they are currently lacking. PMID:26147215

  7. Patterns of Freshwater Species Richness, Endemism, and Vulnerability in California

    PubMed Central

    Furnish, Joseph; Gardali, Thomas; Grantham, Ted; Katz, Jacob V. E.; Kupferberg, Sarah; McIntyre, Patrick; Moyle, Peter B.; Ode, Peter R.; Peek, Ryan; Quiñones, Rebecca M.; Rehn, Andrew C.; Santos, Nick; Schoenig, Steve; Serpa, Larry; Shedd, Jackson D.; Slusark, Joe; Viers, Joshua H.; Wright, Amber; Morrison, Scott A.

    2015-01-01

    The ranges and abundances of species that depend on freshwater habitats are declining worldwide. Efforts to counteract those trends are often hampered by a lack of information about species distribution and conservation status and are often strongly biased toward a few well-studied groups. We identified the 3,906 vascular plants, macroinvertebrates, and vertebrates native to California, USA, that depend on fresh water for at least one stage of their life history. We evaluated the conservation status for these taxa using existing government and non-governmental organization assessments (e.g., endangered species act, NatureServe), created a spatial database of locality observations or distribution information from ~400 data sources, and mapped patterns of richness, endemism, and vulnerability. Although nearly half of all taxa with conservation status (n = 1,939) are vulnerable to extinction, only 114 (6%) of those vulnerable taxa have a legal mandate for protection in the form of formal inclusion on a state or federal endangered species list. Endemic taxa are at greater risk than non-endemics, with 90% of the 927 endemic taxa vulnerable to extinction. Records with spatial data were available for a total of 2,276 species (61%). The patterns of species richness differ depending on the taxonomic group analyzed, but are similar across taxonomic level. No particular taxonomic group represents an umbrella for all species, but hotspots of high richness for listed species cover 40% of the hotspots for all other species and 58% of the hotspots for vulnerable freshwater species. By mapping freshwater species hotspots we show locations that represent the top priority for conservation action in the state. This study identifies opportunities to fill gaps in the evaluation of conservation status for freshwater taxa in California, to address the lack of occurrence information for nearly 40% of freshwater taxa and nearly 40% of watersheds in the state, and to implement adequate protections for freshwater taxa where they are currently lacking. PMID:26147215

  8. User friendly tools to target vulnerable areas at watershed scale: evaluation of the soil vulnerability and conductivity claypan indices

    Technology Transfer Automated Retrieval System (TEKTRAN)

    One finding of the Conservation Effects Assessment Program (CEAP) watershed studies was that Best Management practices (BMPs) were not always installed where most needed: in many watersheds, only a fraction of BMPs were implemented in the most vulnerable areas. While complex computer simulation mode...

  9. What if quality of damage data is poor: an Entity-Vulnerability approach for flood vulnerability assessment

    NASA Astrophysics Data System (ADS)

    Naso, Susanna; Chen, Albert S.; Djordjević, Slobodan; Aronica, Giuseppe T.

    2015-04-01

    The classical approach to flood defence, aimed at reducing the probability of flooding through hard defences, has been substituted by flood risk management approach which accepts the idea of coping with floods and aims at reducing not only the probability of flooding, but also the consequences. In this view, the concept of vulnerability becomes central, such as the (non-structural) measures for its increment. On 22 November 2011, an exceptional rainstorm hit the Longano catchment (North-East part of Sicily, Italy) producing local heavy rainfall, mud-debris flow and flash flooding. The flash flood involved property, buildings, roads and more than 100 commercial estates have suffered severe damages. Some days after the event, the municipality provided people forms to describe the damages that occurred on their properties. Unfortunately, the lack of common guidelines in compiling them, their coarseness and the impossibility to have monetary information on them (such us damage data from previous events), did not allow the implementation of a detailed damage analysis. What we're developing in this work is a method for a qualitative evaluation of the consequences of floods, based on vulnerability curves for structures and classes of entities at risk. The difficulty in deriving the vulnerability curves for different building typologies, as function of the water depth, was due to the lack of quantitative information both on damages caused by previous events and on buildings' value. To solve the problem we submitted a questionnaire to a team of experts asking for an estimation of building damages to different hypothetical inundation depths. What we wanted to obtain was deriving the vulnerability data from technicians' experience, believing in the fundamental importance of the collaboration among research and professional engineers. Through the elaboration and the synthesis of the experts' estimations we derived the vulnerability curves for different building typologies and for inundations of both short and long duration. At the same time we defined the classes of the variable Entity in function of both buildings' asset value and their importance for society. Once the buildings of different typologies are grouped, a GIS-based tool (using hazard information obtained from hydraulic modelling, building parcels, vulnerability curves and entity classes) is used to collocate each element at risk inside an Entity-Vulnerability matrix. The construction of a E-V matrix allow both to understand the actual situation of flood-prone area (and the possible consequences of a flood event) and to study the effectiveness of non-structural measures, just studying how their implementation modifies the distribution of elements at risk inside it. The proposed approach can be useful for authorities responsible for development and periodical review of adaptive flood risk management plans.

  10. Do the Most Vulnerable People Live in the Worst Slums? A Spatial Analysis of Accra, Ghana

    PubMed Central

    Jankowska, Marta M.; Weeks, John R.; Engstrom, Ryan

    2011-01-01

    Slums are examples of localized communities within third world urban systems representing a range of vulnerabilities and adaptive capacities. This study examines vulnerability in relation to flooding, environmental degradation, social-status, demographics, and health in the slums of Accra, Ghana by utilizing a place-based approach informed by fieldwork, remote sensing, census data, and geographically weighted regression. The study objectives are threefold: (1) to move slums from a dichotomous into a continuous classification and examine the spatial patterns of the gradient, (2) develop measures of vulnerability for a developing world city and model the relationship between slums and vulnerability, and (3) to assess if the most vulnerable individuals live in the worst slums. A previously developed slum index is utilized, and four new measures of vulnerability are developed through principle components analysis, including a novel component of health vulnerability based on child mortality. Visualizations of the vulnerability measures assess spatial patterns of vulnerability in Accra. Ordinary least squares, spatial, and geographically weighted regression model the ability of the slum index to predict the four vulnerability measures. The slum index performs well for three of the four vulnerability measures, but is least able to predict health vulnerability underscoring the complex relationship between slums and child mortality in Accra. Finally, quintile analysis demonstrates the elevated prevalence of high vulnerability in places with high slum index scores. PMID:22379509

  11. Free and Open Source Software for land degradation vulnerability assessment

    NASA Astrophysics Data System (ADS)

    Imbrenda, Vito; Calamita, Giuseppe; Coluzzi, Rosa; D'Emilio, Mariagrazia; Lanfredi, Maria Teresa; Perrone, Angela; Ragosta, Maria; Simoniello, Tiziana

    2013-04-01

    Nowadays the role of FOSS software in scientific research is becoming increasingly important. Besides the important issues of reduced costs for licences, legality and security there are many other reasons that make FOSS software attractive. Firstly, making the code opened is a warranty of quality permitting to thousands of developers around the world to check the code and fix bugs rather than rely on vendors claims. FOSS communities are usually enthusiastic about helping other users for solving problems and expand or customize software (flexibility). Most important for this study, the interoperability allows to combine the user-friendly QGIS with the powerful GRASS-GIS and the richness of statistical methods of R in order to process remote sensing data and to perform geo-statistical analysis in one only environment. This study is focused on the land degradation (i.e. the reduction in the capacity of the land to provide ecosystem goods and services and assure its functions) and in particular on the estimation of the vulnerability levels in order to suggest appropriate policy actions to reduce/halt land degradation impacts, using the above mentioned software. The area investigated is the Basilicata Region (Southern Italy) where large natural areas are mixed with anthropized areas. To identify different levels of vulnerability we adopted the Environmentally Sensitive Areas (ESAs) model, based on the combination of indicators related to soil, climate, vegetation and anthropic stress. Such indicators were estimated by using the following data-sources: - Basilicata Region Geoportal to assess soil vulnerability; - DESERTNET2 project to evaluate potential vegetation vulnerability and climate vulnerability; - NDVI-MODIS satellite time series (2000-2010) with 250m resolution, available as 16-day composite from the NASA LP DAAC to characterize the dynamic component of vegetation; - Agricultural Census data 2010, Corine Land Cover 2006 and morphological information to assess the vulnerability to anthropic factors mainly connected with agricultural and grazing management. To achieve the final ESAs Index depicting the overall vulnerability to degradation of the investigated area we applied the geometric mean to cross normalized indices related to each examined component. In this context QGIS was used to display data and to perform basic GIS calculations, whereas GRASS was used for map-algebra operations and image processing. Finally R was used for computing statistical analysis (Principal Component Analysis) aimed to determine the relative importance of each adopted indicator. Our results show that GRASS, QGIS and R software are suitable to map land degradation vulnerability and identify highly vulnerable areas in which rehabilitation/recovery interventions are urgent. In addition they allow us to put into evidence the most important drivers of degradation thus supplying basic information for the setting up of intervention strategies. Ultimately, Free Open Source Software deliver a fair chance for geoscientific investigations thanks to their high interoperability and flexibility enabling to preserve the accuracy of the data and to reduce processing time. Moreover, the presence of several communities that steadily support users allows for achieving high quality results, making free open source software a valuable and easy alternative to conventional commercial software.

  12. Hippocampal developmental vulnerability to methylmercury extends into prepubescence

    PubMed Central

    Obiorah, Maryann; McCandlish, Elizabeth; Buckley, Brian; DiCicco-Bloom, Emanuel

    2015-01-01

    The developing brain is sensitive to environmental toxicants such as methylmercury (MeHg), to which humans are exposed via contaminated seafood. Prenatal exposure in children is associated with learning, memory and IQ deficits, which can result from hippocampal dysfunction. To explore underlying mechanisms, we have used the postnatal day (P7) rat to model the third trimester of human gestation. We previously showed that a single low exposure (0.6 μg/gbw) that approaches human exposure reduced hippocampal neurogenesis in the dentate gyrus (DG) 24 h later, producing later proliferation and memory deficits in adolescence. Yet, the vulnerable stem cell population and period of developmental vulnerability remain undefined. In this study, we find that P7 exposure of stem cells has long-term consequences for adolescent neurogenesis. It reduced the number of mitotic S-phase cells (BrdU), especially those in the highly proliferative Tbr2+ population, and immature neurons (Doublecortin) in adolescence, suggesting partial depletion of the later stem cell pool. To define developmental vulnerability to MeHg in prepubescent (P14) and adolescent (P21) rats, we examined acute 24 h effects of MeHg exposure on mitosis and apoptosis. We found that low exposure did not adversely impact neurogenesis at either age, but that a higher exposure (5 μg/gbw) at P14 reduced the total number of neural stem cells (Sox2+) by 23% and BrdU+ cells by 26% in the DG hilus, suggesting that vulnerability diminishes with age. To determine whether these effects reflect changes in MeHg transfer across the blood brain barrier (BBB), we assessed Hg content in the hippocampus after peripheral injection and found that similar levels (~800 ng/gm) were obtained at 24 h at both P14 and P21, declining in parallel, suggesting that changes in vulnerability depend more on local tissue and cellular mechanisms. Together, we show that MeHg vulnerability declines with age, and that early exposure impairs later neurogenesis in older juveniles. PMID:26029035

  13. Climate Change and Infrastructure, Urban Systems, and Vulnerabilities

    SciTech Connect

    Wilbanks, Thomas J; Fernandez, Steven J

    2014-01-01

    This Technical Report on Climate Change and Infrastructure, Urban Systems, and Vulnerabilities has been prepared for the U.S. Department of Energy by the Oak Ridge National Laboratory in support of the U.S. National Climate Assessment (NCA). It is a summary of the currently existing knowledge base on its topic, nested within a broader framing of issues and questions that need further attention in the longer run. The report arrives at a number of assessment findings, each associated with an evaluation of the level of consensus on that issue within the expert community, the volume of evidence available to support that judgment, and the section of the report that provides an explanation for the finding. Cross-sectoral issues related to infrastructures and urban systems have not received a great deal of attention to date in research literatures in general and climate change assessments in particular. As a result, this technical report is breaking new ground as a component of climate change vulnerability and impact assessments in the U.S., which means that some of its assessment findings are rather speculative, more in the nature of propositions for further study than specific conclusions that are offered with a high level of confidence and research support. But it is a start in addressing questions that are of interest to many policymakers and stakeholders. A central theme of the report is that vulnerabilities and impacts are issues beyond physical infrastructures themselves. The concern is with the value of services provided by infrastructures, where the true consequences of impacts and disruptions involve not only the costs associated with the clean-up, repair, and/or replacement of affected infrastructures but also economic, social, and environmental effects as supply chains are disrupted, economic activities are suspended, and/or social well-being is threatened. Current knowledge indicates that vulnerability concerns tend to be focused on extreme weather events associated with climate change that can disrupt infrastructure services, often cascading across infrastructures because of extensive interdependencies threatening health and local economies, especially in areas where human populations and economic activities are concentrated in urban areas. Vulnerabilities are especially large where infrastructures are subject to multiple stresses, beyond climate change alone; when they are located in areas vulnerable to extreme weather events; and if climate change is severe rather than moderate. But the report also notes that there are promising approaches for risk management, based on emerging lessons from a number of innovative initiatives in U.S. cities and other countries, involving both structural and non-structural (e.g., operational) options.

  14. Vulnerability assessment at a national level in Georgia

    NASA Astrophysics Data System (ADS)

    Tsereteli, N.; Arabidze, V.; Varazanashvili, O.; Gugeshashvili, T.

    2012-04-01

    Vulnerability assessment at a national level in Georgia Nino Tsereteli, Vakhtang Arabidze, Otar Varazanashvili, Tengiz Gugeshashvili The risk always exists when cities are built on. Population growth in cities and urbanization in natural hazard-prone zones leads to infrastructure expansion. The goal of the society is to construct natural hazards resistant infrastructure and minimize the expected losses. This is a complicated task as there is always knowledge deficiency on real seismic hazard and vulnerability. Assessment of vulnerability is vital in risk analysis, as vulnerability is defined in many different ways. Work presented here mostly deals with assessment of infrastructure's and population vulnerability at national level in Georgia. This work was initiated by NATO SFP project "seismic Hazard and Risk Assessment for Southern Caucasus - Eastern Turkey Energy Corridors" and the two work packages WP4 (seismic risk) and WP5 (city scenarios) of risk module of EMME (Earthquake Model of the Middle East Region) project. First step was creation databases (inventory) of elements at risk in GIS. Element at risk were the buildings, population, pipelines. The inventories was studied and Created in GIS for the following categories: Building material, number of stories, number of entrances, condition of building, building period. For pipelines pipe tipe (continous or segmented), material, pipe diameter. Very important is to estimate the initial cost of building for assessment of economic losses. From this purpose the attempt was done and the algorithm of this estimation were prepared taking into account obtained the inventory. Build quality, reliability and durability are of special importance to corresponding state agencies and include different aesthetic, engineering, practical, social, technological and economical aspects. The necessity that all of these aspects satisfy existing normative requirements becomes evident as the building and structures come into exploitation. The long term usage of building is very complex. It relates to the reliability and durability of buildings. The long term usage and durability of a building is determined by the concept of depreciation. Depreciation of an entire building is calculated by summing the products of individual construction unit' depreciation rates and the corresponding value of these units within the building. This method of calculation is based on an assumption that depreciation is proportional to the building's (constructions) useful life. We used this methodology to create a matrix, which provides a way to evaluate the depreciation rates of buildings with different type and construction period and to determine their corresponding value. Finely some attempt was done to investigate how these structures were damaged by various hazards. In other words vulnerability curves were constrained on the basis on the relation between various hazard intensities and damage data.

  15. Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer

    Cancer.gov

    Published on Office of Cancer Genomics (http://ocg.cancer.gov) Home > Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell

  16. Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer

    Cancer.gov

    Published on Office of Cancer Genomics (https://ocg.cancer.gov) Home > Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer Systematic identification of molecular subtype-selective vulnerabilities in

  17. 77 FR 74685 - Chemical Facility Anti-Terrorism Standards (CFATS) Chemical-Terrorism Vulnerability Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-17

    ... (IFR), implementing this statutory mandate at 72 FR 17688. Section 550 of the Homeland Security... SECURITY Chemical Facility Anti-Terrorism Standards (CFATS) Chemical- Terrorism Vulnerability Information... financial information, Chemical-terrorism Vulnerability Information (CVI), Sensitive Security...

  18. MINIMIZING THE VULNERABILITY OF WATER SUPPLIES TO NATURAL AND TERRORIST THREATS

    EPA Science Inventory

    There is increasing concern that drinking water utilities may be vulnerable to attacks by terrorists. In the US the President's Commission on Critical Infrastructure Protection has concluded the US drinking water utilities are vulnerable to physical, cyber and biological terroris...

  19. VuWiki: An Ontology-Based Semantic Wiki for Vulnerability Assessments

    NASA Astrophysics Data System (ADS)

    Khazai, Bijan; Kunz-Plapp, Tina; Büscher, Christian; Wegner, Antje

    2014-05-01

    The concept of vulnerability, as well as its implementation in vulnerability assessments, is used in various disciplines and contexts ranging from disaster management and reduction to ecology, public health or climate change and adaptation, and a corresponding multitude of ideas about how to conceptualize and measure vulnerability exists. Three decades of research in vulnerability have generated a complex and growing body of knowledge that challenges newcomers, practitioners and even experienced researchers. To provide a structured representation of the knowledge field "vulnerability assessment", we have set up an ontology-based semantic wiki for reviewing and representing vulnerability assessments: VuWiki, www.vuwiki.org. Based on a survey of 55 vulnerability assessment studies, we first developed an ontology as an explicit reference system for describing vulnerability assessments. We developed the ontology in a theoretically controlled manner based on general systems theory and guided by principles for ontology development in the field of earth and environment (Raskin and Pan 2005). Four key questions form the first level "branches" or categories of the developed ontology: (1) Vulnerability of what? (2) Vulnerability to what? (3) What reference framework was used in the vulnerability assessment?, and (4) What methodological approach was used in the vulnerability assessment? These questions correspond to the basic, abstract structure of the knowledge domain of vulnerability assessments and have been deduced from theories and concepts of various disciplines. The ontology was then implemented in a semantic wiki which allows for the classification and annotation of vulnerability assessments. As a semantic wiki, VuWiki does not aim at "synthesizing" a holistic and overarching model of vulnerability. Instead, it provides both scientists and practitioners with a uniform ontology as a reference system and offers easy and structured access to the knowledge field of vulnerability assessments with the possibility for any user to retrieve assessments using specific research criteria. Furthermore, Vuwiki can serve as a collaborative knowledge platform that allows for the active participation of those generating and using the knowledge represented in the wiki.

  20. Overestimation of marsh vulnerability to sea level rise

    NASA Astrophysics Data System (ADS)

    Kirwan, Matthew L.; Temmerman, Stijn; Skeehan, Emily E.; Guntenspergen, Glenn R.; Fagherazzi, Sergio

    2016-03-01

    Coastal marshes are considered to be among the most valuable and vulnerable ecosystems on Earth, where the imminent loss of ecosystem services is a feared consequence of sea level rise. However, we show with a meta-analysis that global measurements of marsh elevation change indicate that marshes are generally building at rates similar to or exceeding historical sea level rise, and that process-based models predict survival under a wide range of future sea level scenarios. We argue that marsh vulnerability tends to be overstated because assessment methods often fail to consider biophysical feedback processes known to accelerate soil building with sea level rise, and the potential for marshes to migrate inland.

  1. Assessing the Vulnerability of Agriculture to Climate Change in Jordan

    NASA Astrophysics Data System (ADS)

    Khresat, Sa'eb; Shraidaeh, Fadi; Maddat, Amer

    2015-04-01

    Climate change represents one of the greatest environmental, social and economic threats facing Jordan. In particular, the combined effects of climate change and water scarcity threaten to affect food and water resources that are critical for livelihoods in Jordan. This is especially true for those communities who live in the dryland area in the country and who rely wholly on rain-fed agriculture. The exact nature and extent of the impact of climate change on temperature and precipitation distribution pattern remain uncertain and it is the poor and vulnerable who will be the most susceptible to climate change adverse effects. A vulnerability assessment of rain fed agriculture to climate change and variability in semi-arid parts of Jordan was conducted in 2014. The purpose of this study is to assess the vulnerability and resilience of the most vulnerable groups where rainfed and irrigated agriculture is practiced. Also, the study focused on quantifying the impacts on agricultural productivity in response to climate change. This will help policymakers and researchers better understand and anticipate the likely impacts of climate change on agriculture and on vulnerable communities in Jordan. Also, it will provide them with tools to identify and implement appropriate adaptation strategies. The data used includes; Representative Concentration Pathways (RCPs), RCP 4.5 and RCP 8.5 adopted by the IPCC for its fifth Assessment Report (AR5). Those pathways were used for climate modeling. A decision support system (DSSAT) for agricultural production was used to assess the impact of climate changes on agricultural production. This approach was used for the Identification of climate change risk and their impacts on Agriculture. Outputs from models are used to assess the vulnerability of farmers and crops to climate and socio-economic change by estimating their sensitivity and capacity to adapt to external factors as a means of identifying what causes the differences in their vulnerability. Based on the projection models for the area, average temperature in Jordan is projected to increase between 1.2 and 1.6°C by 2050. These upward temperature trends are projected to continue beyond 2050. Projections for precipitation trends are projected to decrease by 16% by the year 2050. Evaporation is likely to increase due to higher temperatures. This is likely to increase the incidence of drought potential since precipitation is projected to decrease. It is concluded that the Overall vulnerability of agriculture to climate change in Jordan is high, where impacts such as drought and increased temperatures and decreased precipitation will be more pronounced. Major implications on rain fed agriculture are possible shorter growing season, increasing moisture and heat stress to field and horticultural crops and eventually low income and food insecurity. There were different impacts among studied communities, which is related to the: economic capability, local knowledge, physical infrastructure, institutional capacity, modern technology used, age group of farmers and diversification of their income.

  2. Vulnerability and adaptation of US shellfisheries to ocean acidification

    NASA Astrophysics Data System (ADS)

    Ekstrom, Julia A.; Suatoni, Lisa; Cooley, Sarah R.; Pendleton, Linwood H.; Waldbusser, George G.; Cinner, Josh E.; Ritter, Jessica; Langdon, Chris; van Hooidonk, Ruben; Gledhill, Dwight; Wellman, Katharine; Beck, Michael W.; Brander, Luke M.; Rittschof, Dan; Doherty, Carolyn; Edwards, Peter E. T.; Portela, Rosimeiry

    2015-03-01

    Ocean acidification is a global, long-term problem whose ultimate solution requires carbon dioxide reduction at a scope and scale that will take decades to accomplish successfully. Until that is achieved, feasible and locally relevant adaptation and mitigation measures are needed. To help to prioritize societal responses to ocean acidification, we present a spatially explicit, multidisciplinary vulnerability analysis of coastal human communities in the United States. We focus our analysis on shelled mollusc harvests, which are likely to be harmed by ocean acidification. Our results highlight US regions most vulnerable to ocean acidification (and why), important knowledge and information gaps, and opportunities to adapt through local actions. The research illustrates the benefits of integrating natural and social sciences to identify actions and other opportunities while policy, stakeholders and scientists are still in relatively early stages of developing research plans and responses to ocean acidification.

  3. Intracoronary Imaging in the Detection of Vulnerable Plaques.

    PubMed

    Batty, Jonathan A; Subba, Shristy; Luke, Peter; Gigi, Li Wing Chi; Sinclair, Hannah; Kunadian, Vijay

    2016-03-01

    Coronary artery disease is the result of atherosclerotic changes to the coronary arterial wall, comprising endothelial dysfunction, vascular inflammation and deposition of lipid-rich macrophage foam cells. Certain high-risk atherosclerotic plaques are vulnerable to disruption, leading to rupture, thrombosis and the clinical sequelae of acute coronary syndrome. Though recognised as the gold standard for evaluating the presence, distribution and severity of atherosclerotic lesions, invasive coronary angiography is incapable of identifying non-stenotic, vulnerable plaques that are responsible for adverse cardiovascular events. The recognition of such limitations has impelled the development of intracoronary imaging technologies, including intravascular ultrasound, optical coherence tomography and near-infrared spectroscopy, which enable the detailed evaluation of the coronary wall and atherosclerotic plaques in clinical practice. This review discusses the present status of invasive imaging technologies; summarises up-to-date, evidence-based clinical guidelines; and addresses questions that remain unanswered with regard to the future of intracoronary plaque imaging. PMID:26879196

  4. Comprehensive care for vulnerable elderly veterans during disasters.

    PubMed

    Claver, Maria; Dobalian, Aram; Fickel, Jacqueline J; Ricci, Karen A; Mallers, Melanie Horn

    2013-01-01

    Despite problematic evacuation and sheltering of nursing home residents during Hurricanes Katrina and Rita, an exploration of the experiences of Veterans Health Administration (VHA) nursing homes (VANHs) is necessary for a comprehensive examination of the healthcare community's response to these disasters. VANH evacuations during these hurricanes have not been widely studied. This exploratory project aimed to provide information about the evacuation experiences and characteristics of vulnerable nursing home residents. Interviews with key informants from VHA facilities with nursing home staff and representatives revealed that physical harm, psychological distress, cognitive decline and increased social isolation were areas that deserved special attention for this vulnerable population. Moreover, physical, psychological and social needs were interconnected in that each influenced the others. Findings contribute to the general conversation about meeting the biopsychosocial needs of nursing home residents in an integrated healthcare delivery system and more broadly, the role of long-term care facilities in general in planning for future disasters. PMID:22901664

  5. Pandemic Influenza Preparedness and Vulnerable Populations in Tribal Communities

    PubMed Central

    Jim, Cheyenne; LaRoque, Mic; Mason, Cheryl; McLaughlin, Joe; Neel, Lisa; Powell, Terry; Weiser, Thomas; Bryan, Ralph T.

    2009-01-01

    American Indian and Alaska Native (AIAN) governments are sovereign entities with inherent authority to establish and administer public health programs within their communities and will be critical partners in national efforts to prepare for pandemic influenza. Within AIAN communities, some subpopulations will be particularly vulnerable during an influenza pandemic because of their underlying health conditions, whereas others will be at increased risk because of limited access to prevention or treatment interventions.We outline potential issues to consider in identifying and providing appropriate services for selected vulnerable populations within tribal communities. We also highlight pandemic influenza preparedness resources available to tribal leaders and their partners in state and local health departments, academia, community-based organizations, and the private sector. PMID:19461107

  6. [Human vulnerability under cosmetic surgery. A bioethic analysis].

    PubMed

    Ramos-Rocha de Viesca, Mariablanca

    2012-01-01

    Cosmetic surgery is one of the best examples of the current health empowerment. Aesthetic surgical interventions have been criticized because they expose the healthy individual to an unnecessary risk. In modern society the body has turned into a beauty depository with a commercial value. In published bioethics papers, analyses of the cosmetic problem pointed their attention on the freedom, autonomy and distributive justice. Mexico occupies fifth place in the world of cosmetic surgeries. Vulnerability is an inherent condition of man's existence and marks the limit of human dignity. UNESCO agrees that some populations are more inclined to vulnerability. The aim of this work is to demonstrate that those who wish to make a physical change had given up to social coercion and psychological problems. PMID:22768823

  7. Vulnerability and Resilience: A Study of High-Risk Adolescents

    PubMed Central

    Luthar, Suniya S.

    2014-01-01

    Factors that allow children to maintain socially competent behaviors despite stress were examined among 144 inner-city ninth-grade students with a mean age of 15.3 years. Stress was operationalized by scores on a negative life events scale, and definitions of social competence were based on peer ratings, teacher ratings, and school grades. Moderator variables examined included intelligence, internal locus of control, social skills, ego development, and positive life events. Following theoretical models by Garmezy and Rutter, distinctions were made between compensatory factors (which are directly related to competence) and protective/vulnerability factors (which interact with stress in influencing competence). Ego development was found to be compensatory against stress. Internality and social skills proved to be protective factors, while intelligence and positive events were involved in vulnerability processes. This study also revealed that children labeled as resilient were significantly more depressed and anxious than were competent children from low stress backgrounds. PMID:1914628

  8. Cue-Evoked Positive Affect, Depression Vulnerability and Smoking Years

    PubMed Central

    McChargue, Dennis E.; Doran, Neal

    2016-01-01

    Objectives To evaluate whether cue-evoked affective response would moderate the relationship between depression-proneness and smoking years. Methods Depression-proneness profiles were derived using clinician diagnosed personal and family histories of major depression, recurrent depression, trait-anhedonia, and ruminative coping styles (n=70). Affective distress was produced by idiographic, guided negative mood imageries in the presence of an in vivo cigarette exposure. Results Contrary to expectations, results showed that individuals less vulnerable to depression reported longer smoking histories. Stress-induced decreases in positive affect bolstered the association between depression vulnerability and smoking years. Conclusion Depression-proneness assumptions are challenged and implications to affective influences on smoking behavior are discussed. PMID:18844520

  9. [Vulnerability of adolescent students to STD / HIV in Imperatriz - Maranhao].

    PubMed

    Costa, Ana Cristina Pereira de Jesus; Lins, Anamaria Gomes; de Araújo, Márcio Flávio Moura; de Araújo, Thiago Moura; Gubert, Fabiane do Amaral; Vieira, Neiva Francenely Cunha

    2013-09-01

    The aim of this study was to investigate the vulnerability of adolescent students related to sexually transmitted diseases (STD) and the human immunodeficiency virus (HIV), identifying the main risk behaviors and prevention. This quantitative, cross-sectional study was performed in three public schools in Imperatriz--Maranhão, with 295 adolescents, using a structured questionnaire. The results show that: most young people (86.3%) who used a condom the last time they had intercourse, usually keep this practice, 82.8% of adolescents who understand the concept of HIV protect themselves against these infections and believe the main form of contamination is through sex, infected blood or through the placental barrier. We conclude that most teenager participants showed coherent knowledge about sexual practices and risk behaviors that make them vulnerable to STD/HIK presenting a positive aspect for the prevention of these diseases. PMID:24344601

  10. CARVE: The Carbon in Arctic Reservoirs Vulnerability Experiment

    NASA Technical Reports Server (NTRS)

    Miller, Charles E.; Dinardo, Steven J.

    2012-01-01

    The Carbon in Arctic Reservoirs Vulnerability Experiment (CARVE) is a NASA Earth Ventures (EV-1) investigation designed to quantify correlations between atmospheric and surface state variables for the Alaskan terrestrial ecosystems through intensive seasonal aircraft campaigns, ground-based observations, and analysis sustained over a 5-year mission. CARVE bridges critical gaps in our knowledge and understanding of Arctic ecosystems, linkages between the Arctic hydrologic and terrestrial carbon cycles, and the feedbacks from fires and thawing permafrost. CARVE's objectives are to: (1) Directly test hypotheses attributing the mobilization of vulnerable Arctic carbon reservoirs to climate warming; (2) Deliver the first direct measurements and detailed maps of CO2 and CH4 sources on regional scales in the Alaskan Arctic; and (3) Demonstrate new remote sensing and modeling capabilities to quantify feedbacks between carbon fluxes and carbon cycle-climate processes in the Arctic (Figure 1). We describe the investigation design and results from 2011 test flights in Alaska.

  11. Effective Health Risk Communication About Pandemic Influenza for Vulnerable Populations

    PubMed Central

    Tinker, Timothy

    2009-01-01

    The consequences of pandemic influenza for vulnerable populations will depend partly on the effectiveness of health risk communications. Strategic planning should fully consider how life circumstances, cultural values, and perspectives on risk influence behavior during a pandemic. We summarize recent scientific evidence on communication challenges and examine how sociocultural, economic, psychological, and health factors can jeopardize or facilitate public health interventions that require a cooperative public. If ignored, current communication gaps for vulnerable populations could result in unequal protection across society during an influenza pandemic. We offer insights on communication preparedness gleaned from scientific studies and the deliberations of public health experts at a meeting convened by the Centers for Disease Control and Prevention, May 1 and 2, 2008. PMID:19797744

  12. Vulnerability of a killer whale social network to disease outbreaks

    NASA Astrophysics Data System (ADS)

    Guimarães, Paulo R., Jr.; de Menezes, Márcio Argollo; Baird, Robin W.; Lusseau, David; Guimarães, Paulo; Dos Reis, Sérgio F.

    2007-10-01

    Emerging infectious diseases are among the main threats to conservation of biological diversity. A crucial task facing epidemiologists is to predict the vulnerability of populations of endangered animals to disease outbreaks. In this context, the network structure of social interactions within animal populations may affect disease spreading. However, endangered animal populations are often small and to investigate the dynamics of small networks is a difficult task. Using network theory, we show that the social structure of an endangered population of mammal-eating killer whales is vulnerable to disease outbreaks. This feature was found to be a consequence of the combined effects of the topology and strength of social links among individuals. Our results uncover a serious challenge for conservation of the species and its ecosystem. In addition, this study shows that the network approach can be useful to study dynamical processes in very small networks.

  13. Humanitarian responses to mass violence perpetrated against vulnerable populations.

    PubMed Central

    Gellert, G. A.

    1995-01-01

    This multidisciplinary review links three areas of legitimate inquiry for practitioners of medicine and public health. The first is occurrences of mass violence or genocide perpetrated against vulnerable populations, with a focus on the failure of national and international mechanisms to prevent or predict such violence. The second is evolving concepts of national sovereignty and an emerging framework in which the imperative to assist vulnerable populations supersedes a state's right to self determination. The last is how medical, public health, and other systems of surveillance and rapid assessment of mass violence can accelerate public awareness and facilitate structured, consistent political decision making to prevent mass violence and to provide international humanitarian assistance. Images p1000-a PMID:7580643

  14. Vulnerability, Sensitivity, and Coping/Adaptive Capacity Worldwide

    SciTech Connect

    Malone, Elizabeth L.; Brenkert, Antoinette L.

    2009-10-01

    Research and analyses have repeatedly shown that impacts of climate change will be unevenly distributed and will affect various societies in various ways. The severity of impacts will depend in part on ability to cope in the short term and adapt in the longer term. However, it has been difficult to find a comparative basis on which to assess differential impacts of climate change. This chapter describes the Vulnerability-Resilience Indicator Model that uses 18 proxy indicators, grouped into 8 elements, to assess on a quantitative basis the comparative potential vulnerability and resilience of countries to climate change. The model integrates socioeconomic and environmental information such as land use, crop production, water availability, per capita GDP, inequality, and health status. Comparative results for 160 countries are presented and analyzed.

  15. Vulnerability of complex networks under path-based attacks

    NASA Astrophysics Data System (ADS)

    Pu, Cun-Lai; Cui, Wei

    2015-02-01

    We investigate vulnerability of complex networks including model networks and real-world networks subject to path-based attacks. Specifically, we remove approximately the longest simple path from a network iteratively until there are no paths left in the network. We propose two algorithms, the random augmenting approach (RPA) and the Hamilton-path based approach (HPA), for finding the approximately longest simple path in a network. Results demonstrate that steps of longest-path attacks increase with network density linearly for random networks, while exponentially increasing for scale-free networks. The more homogeneous the degree distribution is, the more fragile the network, which is different from the previous results of node or edge attacks. HPA is generally more efficient than RPA in the longest-path attacks of complex networks. These findings further help us understand the vulnerability of complex systems, better protect complex systems, and design more tolerant complex systems.

  16. Vulnerable atherosclerotic plaque metalloproteinases and foam cell phenotypes

    PubMed Central

    Newby, Andrew C.; George, Sarah J.; Ismail, Yasmin; Johnson, Jason L.; Sala-Newby, Graciela B.; Thomas, Anita C.

    2010-01-01

    Summary Plaque rupture underlies most myocardial infarctions. Plaques vulnerable to rupture have thin fibrous caps, an excess of macrophages over vascular smooth muscle cells, large lipid cores, and depletion of collagen and other matrix proteins form the cap and lipid core. Production of matrix metalloproteinases from macrophages is prominent in human plaques, and studies in genetically modified mice imply a causative role for metalloproteinases in plaque vulnerability. Recent in-vitro studies on human monocyte-derived macrophages and on foam-cell macrophages generated in vivo suggest the existence of several macrophage phenotypes with distinct patterns of metalloproteinase expression. These phenotypes could play differing roles in cap, core and aneurysm formation. PMID:19492140

  17. Existential vulnerability: toward a psychopathology of limit situations.

    PubMed

    Fuchs, Thomas

    2013-01-01

    Jaspers' concept of limit situations seems particularly appropriate not only to elucidate outstanding existential situations in general, but also basic preconditions for the occurrence of mental disorders. For this purpose, the concept is first explained in Jaspers' sense and then related to an 'existential vulnerability' of mentally ill persons that makes them experience even inconspicuous events as distressing limit situations. In such situations, an otherwise hidden fundamental condition of existence becomes manifest for them, e.g. the fragility of one's own body, the inevitability of freedom, or the finiteness of life. This fundamental condition is found unbearable and, as a reaction, gives rise to mental illness. This concept of existential vulnerability is illustrated by some psychopathological examples. PMID:23860487

  18. A Neural Biomarker of Psychological Vulnerability to Future Life Stress

    PubMed Central

    Swartz, Johnna R.; Knodt, Annchen R.; Radtke, Spenser R.; Hariri, Ahmad R.

    2014-01-01

    Summary We all experience a host of common life stressors such as the death of a family member, medical illness, and financial uncertainty. While most of us are resilient to such stressors, continuing to function normally, for a subset of individuals, experiencing these stressors increases the likelihood of developing treatment-resistant, chronic psychological problems, including depression and anxiety. It is thus paramount to identify predictive markers of risk, particularly those reflecting fundamental biological processes that can be targets for intervention and prevention. Using data from a longitudinal study of 340 healthy young adults, we demonstrate that individual differences in threat-related amygdala reactivity predict psychological vulnerability to life stress occurring as much as 1 to 4 years later. These results highlight a readily assayed biomarker, threat-related amygdala reactivity, which predicts psychological vulnerability to commonly experienced stressors and represents a discrete target for intervention and prevention. PMID:25654256

  19. Caring for vulnerable ostomists: learning disabilities and stoma care.

    PubMed

    Parker, Michaela

    It is without doubt that people with learning difficulties are considered vulnerable and meeting the healthcare needs of this group in society is now recognised as a challenging task. This case study examines the implications of life with a stoma for one particular man with learning difficulties and reflects on the key issues that have influenced his care: stigma and isolation, general healthcare needs for people with learning disabilities and the association with stoma care, and the provision of care and whose role it is. Key findings include inconsistencies between primary, secondary and social care, resulting in lack of integration and flexibility in provision of care; lack of responsibility for care, with a 'pass the buck' response; lack of knowledge about stoma care in most care settings; and, as a stoma care nurse, the importance of personal instinct, along with persistence in advocating appropriate levels of care for vulnerable ostomists. PMID:23123618

  20. Subsidence vulnerability in shallow room-and-pillar mines

    SciTech Connect

    Missavage, R.

    1985-07-01

    Concern over mining-related subsidence is inhibiting the development of surface land uses in previously mined areas and is constraining the recovery of coal resources in areas with established land uses that might be impacted by subsequent subsidence. The determination of subsidence vulnerability of mined-out areas (especially abandoned mine areas) can be a useful tool in the design and location of surface structures. A model has been developed for assessing subsidence vulnerability in shallow room-and-pillar mines based on the flexural rigidity and strength characteristics of the overlying strata. The model does not predict the subsidence profile or when the subsidence will occur. It only predicts those areas that are likely to subside. This paper briefly describes the model and its testing.

  1. Accounting for the Impact of Impermeable Soil Layers on Pesticide Runoff and Leaching in a Landscape Vulnerability Model

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A regional-scale model that estimates landscape vulnerability of pesticide leaching and runoff (solution and particle adsorbed) underestimated runoff vulnerability and overestimated leaching vulnerability compared to measured data when applied to a gently rolling landscape in northeast Missouri. Man...

  2. Assessment of human–natural system characteristics influencing global freshwater supply vulnerability

    NASA Astrophysics Data System (ADS)

    Padowski, Julie C.; Gorelick, Steven M.; Thompson, Barton H.; Rozelle, Scott; Fendorf, Scott

    2015-10-01

    Global freshwater vulnerability is a product of environmental and human dimensions, however, it is rarely assessed as such. Our approach identifies freshwater vulnerability using four broad categories: endowment, demand, infrastructure, and institutions, to capture impacts on natural and managed water systems within the coupled human–hydrologic environment. These categories are represented by 19 different endogenous and exogenous characteristics affecting water supply vulnerability. By evaluating 119 lower per capita income countries (<10 725), we find that every nation experiences some form of vulnerability. Institutional vulnerability is experienced most commonly, occurring in 44 nations, and 23 countries suffer deficiencies in all four categories. Of these highly vulnerable countries, Jordan is the most vulnerable, reporting the greatest number of characteristics (5 of 19) at critical vulnerability levels, with Yemen and Djibouti nearly as vulnerable. Surprising similarities in vulnerability were also found among geographically disparate nations such as Vietnam, Sri Lanka, and Guatemala. Determining shared patterns of freshwater vulnerability provides insights into why water supply vulnerabilities are manifested in human–water systems at the national scale.

  3. 76 FR 55673 - Vulnerability Assessments in Support of the Climate Ready Estuaries Program: A Novel Approach...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-08

    ... AGENCY Vulnerability Assessments in Support of the Climate Ready Estuaries Program: A Novel Approach... period for the draft documents titled, Vulnerability Assessments in Support of the Climate Ready... Partnership (EPA/600/R-11/ 058a) and Vulnerability Assessments in Support of the Climate Ready...

  4. 75 FR 51806 - Climate Change Vulnerability Assessment: Four Case Studies of Water Utility Practices

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ... AGENCY Climate Change Vulnerability Assessment: Four Case Studies of Water Utility Practices AGENCY...-day public comment period for the draft document titled, ``Climate Change Vulnerability Assessment... utilities to assess their vulnerability to future climate change. The report is intended to illustrate...

  5. Social vulnerability to climate change in primary producers: A typology approach

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Adaptation in agro-ecological systems will be important for moderating the impacts of climate change. Vulnerability assessments provide the basis for developing strategies to reduce social vulnerability and plan for climate adaptation. Primary industries have been identified as the most vulnerable i...

  6. Multi-vulnerability assessment for flash flood risk management in East Attica, Greece

    NASA Astrophysics Data System (ADS)

    Karagiorgos, Konstantinos; Thaler, Thomas; Hübl, Johannes; Maris, Fotios; Mallinis, Giorgos; Fuchs, Sven

    2015-04-01

    Vulnerability assessment implies a quantitative evaluation of the individual vulnerability components such as elements at risk, their physical exposure and social characteristics. Current approaches in vulnerability research are driven by a divide between social scientists who tend to view vulnerability as representing a set of socio-economic factors, and scientists who view vulnerability in terms of the degree of loss to an element at risk. To close this gap, a multi-dimensional vulnerability analysis has been undertaken focusing on flash flood hazards in Greece. To represent physical vulnerability, an empirical relation between the process intensity and the degree of loss was established. With respect to social vulnerability, an assessment was undertaken by means of empirical data collection based on a door-to-door survey. In general, both physical and social vulnerability was comparable low, which is interpreted as a result from (a) specific building regulations in Greece as well as general design principles leading to less structural susceptibility of elements at risk exposed, and (b) a relatively low economic loss leading to less social vulnerability of citizens exposed. It is shown that a combination of different perspectives of vulnerability will lead to a better understanding of perceptions of actors regarding their vulnerabilities and capacities.

  7. Perceptions of Vulnerability to HIV/AIDS: A Comparison of Two College Cohorts, 1990 and 2005

    ERIC Educational Resources Information Center

    Teague, Susan M.

    2009-01-01

    Theories of preventive health behavior posit that perceived vulnerability to health threats motivates self-protective behavior. Fifteen years after an initial study of college students' perceptions of their vulnerability to HIV, a replication was conducted on the same campus in 2005. Comparisons between cohorts on vulnerability judgements were…

  8. Perceptions of Vulnerability to HIV/AIDS: A Comparison of Two College Cohorts, 1990 and 2005

    ERIC Educational Resources Information Center

    Teague, Susan M.

    2009-01-01

    Theories of preventive health behavior posit that perceived vulnerability to health threats motivates self-protective behavior. Fifteen years after an initial study of college students' perceptions of their vulnerability to HIV, a replication was conducted on the same campus in 2005. Comparisons between cohorts on vulnerability judgements were…

  9. Local spatial and temporal factors influencing population and societal vulnerability to natural disasters.

    PubMed

    Zhou, Yang; Li, Ning; Wu, Wenxiang; Wu, Jidong; Shi, Peijun

    2014-04-01

    The identification of societal vulnerable counties and regions and the factors contributing to social vulnerability are crucial for effective disaster risk management. Significant advances have been made in the study of social vulnerability over the past two decades, but we still know little regarding China's societal vulnerability profiles, especially at the county level. This study investigates the county-level spatial and temporal patterns in social vulnerability in China from 1980 to 2010. Based on China's four most recent population censuses of 2,361 counties and their corresponding socioeconomic data, a social vulnerability index for each county was created using factor analysis. Exploratory spatial data analysis, including global and local autocorrelations, was applied to reveal the spatial patterns of county-level social vulnerability. The results demonstrate that the dynamic characteristics of China's county-level social vulnerability are notably distinct, and the dominant contributors to societal vulnerability for all of the years studied were rural character, development (urbanization), and economic status. The spatial clustering patterns of social vulnerability to natural disasters in China exhibited a gathering-scattering-gathering pattern over time. Further investigations indicate that many counties in the eastern coastal area of China are experiencing a detectable increase in social vulnerability, whereas the societal vulnerability of many counties in the western and northern areas of China has significantly decreased over the past three decades. These findings will provide policymakers with a sound scientific basis for disaster prevention and mitigation decisions. PMID:24673569

  10. Vulnerable Children, Communities and Schools: Lessons from Three HIV/AIDS Affected Areas

    ERIC Educational Resources Information Center

    Kendall, Nancy; O'Gara, Chloe

    2007-01-01

    The growing number of children made vulnerable by HIV/AIDS threatens the achievement of Education for All (EFA) and Millennium Development goals. Policy recommendations assign schools key roles in meeting the needs of vulnerable children, but there is a dearth of evidence about how vulnerable children and schools interact in AIDS affected…

  11. Sensitivity of estuaries to sea level rise: Vulnerability indices

    NASA Astrophysics Data System (ADS)

    Prandle, David; Lane, Andrew

    2015-07-01

    This study addresses the question of how tidally-dominated estuaries will adapt to rises in mean sea level and changes in river flows associated with global climate change. The aim was to develop generic 'Vulnerability Indices' to provide immediate indications of relative resilience or sensitivity. Four indices indicate the likely impacts on: (1) Mass flow, (2) Energetics, (3) Vertical mixing and (4) Salinity intrusion.

  12. [Precarity, vulnerability, anticipating end-of-life care at home].

    PubMed

    Bonneval, Camille

    2016-02-01

    Many patients want to end their life at home. Care teams adapt to these wishes and organise a form of treatment which blends safety of care and the respect of the expectations of the patients and family members. When factors of precarity increase the vulnerability inherent to the end of life, caregivers anticipate and support as best as they can the difficulties encountered as testified by a hospital at home team in Dax. PMID:26861082

  13. Martyrdom redefined: self-destructive killers and vulnerable narcissism.

    PubMed

    Bobadilla, Leonardo

    2014-08-01

    Lankford shows that suicide terrorists have much in common with maladjusted persons who die by suicide. However, what differentiates suicidal killers from those who "only" commit suicide? A key element may be vulnerable narcissism. Narcissism has been simultaneously linked to interpersonal aggression, achievement, and depression. These traits may explain the paradoxical picture of a person who may appear "normal" in some aspects, and yet hate himself and others so intensely as to seek mutual destruction. PMID:25162842

  14. Temperature-based Instanton Analysis: Identifying Vulnerability in Transmission Networks

    SciTech Connect

    Kersulis, Jonas; Hiskens, Ian; Chertkov, Michael; Backhaus, Scott N.; Bienstock, Daniel

    2015-04-08

    A time-coupled instanton method for characterizing transmission network vulnerability to wind generation fluctuation is presented. To extend prior instanton work to multiple-time-step analysis, line constraints are specified in terms of temperature rather than current. An optimization formulation is developed to express the minimum wind forecast deviation such that at least one line is driven to its thermal limit. Results are shown for an IEEE RTS-96 system with several wind-farms.

  15. Women migrant workers' vulnerability to HIV infection in Hong Kong.

    PubMed

    Bandyopadhyay, M; Thomas, J

    2002-08-01

    Research on population mobility and HIV/AIDS risk among migrant populations is quite limited, and research on migrant women workers' vulnerability is further limited. Hong Kong, the Special Administrative Region of China, has currently about 200,000 women migrant workers working as domestic helps. This paper reports migrant women worker's access to AIDS-related health information and health care facilities, perceptions about vulnerability, and risk behaviour profile. Data was collected through a pre-tested questionnaire from a random sample of 2,010 women migrant workers. A majority of the migrant women workers (63.6%) have been living and working in Hong Kong for between 4-10 years. Fifty-four per cent of the respondents felt that being a female they were vulnerable to HIV infection. Overall, the knowledge regarding HIV/AIDS and its route of transmission is inadequate amongst the migrant women workers in Hong Kong. It appears that AIDS-related information education and communication needs of women migrants workers are not met by the current HIV prevention and care activities in Hong Kong. The study indicates that migrant women workers who experienced sexual violence (9%) in Hong Kong perceive themselves to be 'at risk' of HIV infection. Seventy per cent of the respondents reported that they have felt discriminated against in Hong Kong, of which 42% felt discriminated against in Hong Kong hospitals. Addressing discrimination in health care settings is an essential element of AIDS prevention. The discussion urges researchers and policy makers to pay more attention to the vulnerability of migrant women workers. PMID:12204153

  16. American Indian adolescent girls: vulnerability to sex trafficking, intervention strategies.

    PubMed

    Pierce, Alexandra Sandi

    2012-01-01

    The Minnesota Indian Women's Resource Center offers harm reduction programming to at-risk adolescent American Indian girls, including outreach, case management, advocacy, healthy sexuality education, and support groups. To evaluate program impact, participants are assessed at intake and every 6 months afterward for current vulnerability to commercial sexual exploitation, violence, and addiction. Evaluation results indicate frequent exposure to sex traffickers and suggest that harm reduction methods can help girls reduce risk of commercial sexual exploitation. PMID:22569724

  17. Vulnerability to mild predator stress in serotonin transporter knockout mice.

    PubMed

    Adamec, Robert; Burton, Paul; Blundell, Jacqueline; Murphy, Dennis L; Holmes, Andrew

    2006-06-01

    Effect of predator stress on rat and mouse anxiety-like behavior may model aspects of post traumatic stress disorder (PTSD). A single cat exposure of wild type (C57, CFW) mice can produce lasting anxiety-like effects in the elevated plus maze, light/dark box tests and startle. In addition, female but not male C57 mice are made more anxious in the plus maze by exposure to predator odors alone, suggesting differential vulnerability to predator stressors of differing intensity. There is a link between genetic variation in the serotonin (5-HT) transporter (SERT) and anxiety in humans. This prompted the generation of SERT knockout mice [see Holmes A, Murphy DL, Crawley, JN. Biol Psychiatry 2003;54(10):953-9]. Present work used these mice to determine if there was a link between vulnerability to the anxiogenic effects of predator odors and abnormalities of 5-HT transmission induced by a life long reduction in 5-HT reuptake. Wild type (WT, C57 background), heterozygous (SERT +/-, HET) mice and homozygous knockout (SERT -/-, KO) were assigned to handled control groups or groups exposed for 10 min to a large testing room rich in cat odor. One week after handling or room exposure, anxiety testing took place in the dark phase of the light/dark cycle, in red light. Predator odor exposure was selectively anxiogenic in the plus maze and light/dark box tests in SERT -/- mice. Exposure to predator odor did not potentiate startle. Findings suggest a role for abnormalities in 5-HT transmission in vulnerability to some of the lasting anxiogenic effects of species relevant stressors and possibly in vulnerability to PTSD. PMID:16546269

  18. Socioeconomic factors and vulnerability to outbreaks of leptospirosis in Nicaragua.

    PubMed

    Bacallao, Jorge; Schneider, Maria Cristina; Najera, Patricia; Aldighieri, Sylvain; Soto, Aida; Marquiño, Wilmer; Sáenz, Carlos; Jiménez, Eduardo; Moreno, Gilberto; Chávez, Octavio; Galan, Deise I; Espinal, Marcos A

    2014-08-01

    Leptospirosis is an epidemic-prone zoonotic disease that occurs worldwide, with more than 500,000 human cases reported annually. It is influenced by environmental and socioeconomic factors that affect the occurrence of outbreaks and the incidence of the disease. Critical areas and potential drivers for leptospirosis outbreaks have been identified in Nicaragua, where several conditions converge and create an appropriate scenario for the development of leptospirosis. The objectives of this study were to explore possible socioeconomic variables related to leptospirosis critical areas and to construct and validate a vulnerability index based on municipal socioeconomic indicators. Municipalities with lower socioeconomic status (greater unsatisfied basic needs for quality of the household and for sanitary services, and higher extreme poverty and illiteracy rates) were identified with the highest leptospirosis rates. The municipalities with highest local vulnerability index should be the priority for intervention. A distinction between risk given by environmental factors and vulnerability to risk given by socioeconomic conditions was shown as important, which also applies to the "causes of outbreaks" and "causes of cases". PMID:25153463

  19. Climate Change Vulnerability Assessment for Idaho National Laboratory

    SciTech Connect

    Christopher P. Ischay; Ernest L. Fossum; Polly C. Buotte; Jeffrey A. Hicke; Alexander Peterson

    2014-10-01

    The University of Idaho (UI) was asked to participate in the development of a climate change vulnerability assessment for Idaho National Laboratory (INL). This report describes the outcome of that assessment. The climate change happening now, due in large part to human activities, is expected to continue in the future. UI and INL used a common framework for assessing vulnerability that considers exposure (future climate change), sensitivity (system or component responses to climate), impact (exposure combined with sensitivity), and adaptive capacity (capability of INL to modify operations to minimize climate change impacts) to assess vulnerability. Analyses of climate change (exposure) revealed that warming that is ongoing at INL will continue in the coming decades, with increased warming in later decades and under scenarios of greater greenhouse gas emissions. Projections of precipitation are more uncertain, with multi model means exhibiting somewhat wetter conditions and more wet days per year. Additional impacts relevant to INL include estimates of more burned area and increased evaporation and transpiration, leading to reduced soil moisture and plant growth.

  20. Socioeconomic Factors and Vulnerability to Outbreaks of Leptospirosis in Nicaragua

    PubMed Central

    Bacallao, Jorge; Schneider, Maria Cristina; Najera, Patricia; Aldighieri, Sylvain; Soto, Aida; Marquiño, Wilmer; Sáenz, Carlos; Jiménez, Eduardo; Moreno, Gilberto; Chávez, Octavio; Galan, Deise I.; Espinal, Marcos A.

    2014-01-01

    Leptospirosis is an epidemic-prone zoonotic disease that occurs worldwide, with more than 500,000 human cases reported annually. It is influenced by environmental and socioeconomic factors that affect the occurrence of outbreaks and the incidence of the disease. Critical areas and potential drivers for leptospirosis outbreaks have been identified in Nicaragua, where several conditions converge and create an appropriate scenario for the development of leptospirosis. The objectives of this study were to explore possible socioeconomic variables related to leptospirosis critical areas and to construct and validate a vulnerability index based on municipal socioeconomic indicators. Municipalities with lower socioeconomic status (greater unsatisfied basic needs for quality of the household and for sanitary services, and higher extreme poverty and illiteracy rates) were identified with the highest leptospirosis rates. The municipalities with highest local vulnerability index should be the priority for intervention. A distinction between risk given by environmental factors and vulnerability to risk given by socioeconomic conditions was shown as important, which also applies to the “causes of outbreaks” and “causes of cases”. PMID:25153463

  1. Life histories predict vulnerability to overexploitation in parrotfishes

    NASA Astrophysics Data System (ADS)

    Taylor, Brett M.; Houk, Peter; Russ, Garry R.; Choat, J. Howard

    2014-12-01

    A scarcity of life-history data currently exists for many exploited coral reef fishes, hindering our ability to interpret fishery dynamics and develop sound conservation policies. In particular, parrotfishes (Family Labridae) represent a ubiquitous and ecologically important group that is increasingly prevalent in commercial and artisanal fisheries worldwide. We used both fishery-dependent and fishery-independent data to examine the effect of life histories on vulnerability to overexploitation in parrotfishes. Vulnerability for each species was derived from independent measures associated with both temporal (20-year catch records) and spatial datasets. Most life-history traits examined were significant predictors of vulnerability across species, but their relative utility differed considerably. Length-based traits (e.g., lengths at maturity and sex change, maximum length) were generally superior to age-based traits (e.g., life span), but one age-based trait, age at female maturation, was the best predictor. The results suggest that easily derived metrics such as maximum length can be effective measures of sensitivity to exploitation when applied to phylogenetically related multispecies assemblages, but more holistic and comprehensive age-based demographic data should be sought, especially in data-deficient and heavily impacted regions. Given the increasing prevalence of parrotfishes in the global coral reef harvest, species-specific responses demonstrate the capacity for heavy fishing pressure to alter parrotfish assemblages considerably.

  2. Improving delivery of primary care for vulnerable migrants

    PubMed Central

    Pottie, Kevin; Batista, Ricardo; Mayhew, Maureen; Mota, Lorena; Grant, Karen

    2014-01-01

    Abstract Objective To identify and prioritize innovative strategies to address the health concerns of vulnerable migrant populations. Design Modified Delphi consensus process. Setting Canada. Participants Forty-one primary care practitioners, including family physicians and nurse practitioners, who provided care for migrant populations. Methods We used a modified Delphi consensus process to identify and prioritize innovative strategies that could potentially improve the delivery of primary health care for vulnerable migrants. Forty-one primary care practitioners from various centres across Canada who cared for migrant populations proposed strategies and participated in the consensus process. Main findings The response rate was 93% for the first round. The 3 most highly ranked practice strategies to address delivery challenges for migrants were language interpretation, comprehensive interdisciplinary care, and evidence-based guidelines. Training and mentorship for practitioners, intersectoral collaboration, and immigrant community engagement ranked fourth, fifth, and sixth, respectively, as strategies to address delivery challenges. These strategies aligned with strategies coming out of the United States, Europe, and Australia, with the exception of the proposed evidence-based guidelines. Conclusion Primary health care practices across Canada now need to evolve to address the challenges inherent in caring for vulnerable migrants. The selected strategies provide guidance for practices and health systems interested in improving health care delivery for migrant populations. PMID:24452576

  3. Community clusters of tsunami vulnerability in the US Pacific Northwest.

    PubMed

    Wood, Nathan J; Jones, Jeanne; Spielman, Seth; Schmidtlein, Mathew C

    2015-04-28

    Many coastal communities throughout the world are threatened by local (or near-field) tsunamis that could inundate low-lying areas in a matter of minutes after generation. Although the hazard and sustainability literature often frames vulnerability conceptually as a multidimensional issue involving exposure, sensitivity, and resilience to a hazard, assessments often focus on one element or do not recognize the hazard context. We introduce an analytical framework for describing variations in population vulnerability to tsunami hazards that integrates (i) geospatial approaches to identify the number and characteristics of people in hazard zones, (ii) anisotropic path distance models to estimate evacuation travel times to safety, and (iii) cluster analysis to classify communities with similar vulnerability. We demonstrate this approach by classifying 49 incorporated cities, 7 tribal reservations, and 17 counties from northern California to northern Washington that are directly threatened by tsunami waves associated with a Cascadia subduction zone earthquake. Results suggest three primary community groups: (i) relatively low numbers of exposed populations with varied demographic sensitivities, (ii) high numbers of exposed populations but sufficient time to evacuate before wave arrival, and (iii) moderate numbers of exposed populations but insufficient time to evacuate. Results can be used to enhance general hazard-awareness efforts with targeted interventions, such as education and outreach tailored to local demographics, evacuation training, and/or vertical evacuation refuges. PMID:25870283

  4. Epigenetic vulnerability and the environmental influence on health.

    PubMed

    Gomes, Marcus Vinicius de Matos; Pelosi, Gislaine Garcia

    2013-08-01

    A growing body of evidence has drawn the attention of the scientific community by indicating the potential vulnerability to environmental changes of epigenetic mechanisms that control gene expression. Being critical components of normal development, the importance of epigenetic mechanisms for normal biology is illustrated by the fact that abnormal epigenetic patterns have increasingly been linked to the aetiology of various diseases including cancer, paediatric syndromes, autoimmune diseases, genetic disorders and even the molecular process of ageing. It is estimated that the degree of vulnerability to changes in epigenetic patterns is high during early embryonic development, a period of life in which epigenetic patterns are established and cell differentiation is intense. Moreover, increasing amounts of relevant data and information reveal that the environment might potentially impact on epigenetic patterns at every period of life. Within this context, in this study we will review the principles of epigenetic vulnerability to environmental changes, the impacts on development, the association with the origin of common diseases and also speculate about the potential of lifestyle changes to modulate epigenetic patterns and contribute to preventing common diseases. PMID:23828586

  5. Community clusters of tsunami vulnerability in the US Pacific Northwest

    PubMed Central

    Wood, Nathan J.; Jones, Jeanne; Spielman, Seth; Schmidtlein, Mathew C.

    2015-01-01

    Many coastal communities throughout the world are threatened by local (or near-field) tsunamis that could inundate low-lying areas in a matter of minutes after generation. Although the hazard and sustainability literature often frames vulnerability conceptually as a multidimensional issue involving exposure, sensitivity, and resilience to a hazard, assessments often focus on one element or do not recognize the hazard context. We introduce an analytical framework for describing variations in population vulnerability to tsunami hazards that integrates (i) geospatial approaches to identify the number and characteristics of people in hazard zones, (ii) anisotropic path distance models to estimate evacuation travel times to safety, and (iii) cluster analysis to classify communities with similar vulnerability. We demonstrate this approach by classifying 49 incorporated cities, 7 tribal reservations, and 17 counties from northern California to northern Washington that are directly threatened by tsunami waves associated with a Cascadia subduction zone earthquake. Results suggest three primary community groups: (i) relatively low numbers of exposed populations with varied demographic sensitivities, (ii) high numbers of exposed populations but sufficient time to evacuate before wave arrival, and (iii) moderate numbers of exposed populations but insufficient time to evacuate. Results can be used to enhance general hazard-awareness efforts with targeted interventions, such as education and outreach tailored to local demographics, evacuation training, and/or vertical evacuation refuges. PMID:25870283

  6. Npas4 deficiency increases vulnerability to juvenile stress in mice.

    PubMed

    Coutellier, Laurence; Gilbert, Valerie; Shepard, Ryan

    2015-12-15

    During specific windows of postnatal brain development, individuals are particularly susceptible to developing mental illnesses in adulthood. Adolescence is such a window during which environmental stress can have long-lasting consequences on social and cognitive functions. In individuals, highly vulnerable to stress, a relatively mild stressful situation can trigger the onset of psychiatric conditions. The genetic factors and mechanisms underlying vulnerability to stress are not well understood. Here, we show that variations in expression of the brain-specific transcription factor Npas4 contributes to the long-term consequences of juvenile stress on cognitive abilities. We observed that transgenic Npas4-deficient mice exposed to chronic mild stress during adolescence (but not during adulthood) develop prefrontal cortex-dependent cognitive deficits in adulthood, while the same stress did not affect Npas4 wild-type mice. These cognitive deficits were accompanied by fewer neuroblasts in the subventricular zone, and reduced ability of these immature neuronal cells to migrate away from this neurogenic zone toward cortical regions. These findings suggest for the first time that the transcription factor Npas4 could play a significant role in coping with juvenile stress. They also suggest that Npas4 could modulate resilience or vulnerability to stress by mediating the effects of stress on neurogenesis. PMID:25911220

  7. Parkinson’s disease: animal models and dopaminergic cell vulnerability

    PubMed Central

    Blesa, Javier; Przedborski, Serge

    2014-01-01

    Parkinson’s disease (PD) is a neurodegenerative disorder that affects about 1.5% of the global population over 65 years of age. A hallmark feature of PD is the degeneration of the dopamine (DA) neurons in the substantia nigra pars compacta (SNc) and the consequent striatal DA deficiency. Yet, the pathogenesis of PD remains unclear. Despite tremendous growth in recent years in our knowledge of the molecular basis of PD and the molecular pathways of cell death, important questions remain, such as: (1) why are SNc cells especially vulnerable; (2) which mechanisms underlie progressive SNc cell loss; and (3) what do Lewy bodies or α-synuclein reveal about disease progression. Understanding the variable vulnerability of the dopaminergic neurons from the midbrain and the mechanisms whereby pathology becomes widespread are some of the primary objectives of research in PD. Animal models are the best tools to study the pathogenesis of PD. The identification of PD-related genes has led to the development of genetic PD models as an alternative to the classical toxin-based ones, but does the dopaminergic neuronal loss in actual animal models adequately recapitulate that of the human disease? The selection of a particular animal model is very important for the specific goals of the different experiments. In this review, we provide a summary of our current knowledge about the different in vivo models of PD that are used in relation to the vulnerability of the dopaminergic neurons in the midbrain in the pathogenesis of PD. PMID:25565980

  8. General Vulnerability and Exposure Profile to Tsunami in Puerto Rico

    NASA Astrophysics Data System (ADS)

    Ruiz, R.; Huérfano-Moreno, V.

    2012-12-01

    The Puerto Rico archipelago, located in the seismically active Caribbean region, has been directly affected by tsunamis in the last two centuries. The M 7.3 tsunamigenic earthquake, which occurred on October 11, 1918, caused $29 million in damage, death of 116 people and 100 residents were reported as missing. Presently, deficiencies on urban planning have induced an increase on the number of vulnerable people living inside the tsunami flood areas. Tsunami-prone areas have been delimited for Puerto Rico based on numerical tsunami modeling. However, the demographic, social and physical (e.g. critical and essential facilities) characteristics of these areas have not been documented in detail. We are conducting a municipality and community-level tsunami vulnerability and exposure study using Geographical Information System (GIS) tool. The results of our study are being integrated into the Puerto Rico Disaster Decision Support Tool (DDST). The DDST is a tool that brings access, at no cost, to a variety of updated geo-referenced information for Puerto Rico. This tool provides internet-based scalable maps that will aid emergency managers and decision-makers on their responsibilities and will improve Puerto Rico communities' resilience against tsunami hazard. This project aims to provide an initial estimate of Puerto Rico vulnerability and exposure to tsunami and brings to the community a technological tool that will help increase their awareness of this hazard and to assist them on their decisions.

  9. Vulnerability to temperature-related mortality in Seoul, Korea

    NASA Astrophysics Data System (ADS)

    Son, Ji-Young; Lee, Jong-Tae; Anderson, G. Brooke; Bell, Michelle L.

    2011-07-01

    Studies indicate that the mortality effects of temperature may vary by population and region, although little is known about the vulnerability of subgroups to these risks in Korea. This study examined the relationship between temperature and cause-specific mortality for Seoul, Korea, for the period 2000-7, including whether some subgroups are particularly vulnerable with respect to sex, age, education and place of death. The authors applied time-series models allowing nonlinear relationships for heat- and cold-related mortality, and generated exposure-response curves. Both high and low ambient temperatures were associated with increased risk for daily mortality. Mortality risk was 10.2% (95% confidence interval 7.43, 13.0%) higher at the 90th percentile of daily mean temperatures (25 °C) compared to the 50th percentile (15 °C). Mortality risk was 12.2% (3.69, 21.3%) comparing the 10th (-1 °C) and 50th percentiles of temperature. Cardiovascular deaths showed a higher risk to cold, whereas respiratory deaths showed a higher risk to heat effect, although the differences were not statistically significant. Susceptible populations were identified such as females, the elderly, those with no education, and deaths occurring outside of a hospital for heat- and cold-related total mortality. Our findings provide supportive evidence of a temperature-mortality relationship in Korea and indicate that some subpopulations are particularly vulnerable.

  10. Assessment of floodplain vulnerability during extreme Mississippi River flood 2011.

    PubMed

    Goodwell, Allison E; Zhu, Zhenduo; Dutta, Debsunder; Greenberg, Jonathan A; Kumar, Praveen; Garcia, Marcelo H; Rhoads, Bruce L; Holmes, Robert R; Parker, Gary; Berretta, David P; Jacobson, Robert B

    2014-01-01

    Regional change in the variability and magnitude of flooding could be a major consequence of future global climate change. Extreme floods have the capacity to rapidly transform landscapes and expose landscape vulnerabilities through highly variable spatial patterns of inundation, erosion, and deposition. We use the historic activation of the Birds Point-New Madrid Floodway during the Mississippi and Ohio River Flooding of 2011 as a scientifically unique stress experiment to analyze indicators of floodplain vulnerability. We use pre- and postflood airborne Light Detection and Ranging data sets to locate erosional and depositional hotspots over the 540 km(2) agricultural Floodway. While riparian vegetation between the river and the main levee breach likely prevented widespread deposition, localized scour and deposition occurred near the levee breaches. Eroded gullies nearly 1 km in length were observed at a low ridge of a relict meander scar of the Mississippi River. Our flow modeling and spatial mapping analysis attributes this vulnerability to a combination of erodible soils, flow acceleration associated with legacy fluvial landforms, and a lack of woody vegetation to anchor soil and enhance flow resistance. Results from this study could guide future mitigation and adaptation measures in cases of extreme flooding. PMID:24512322

  11. Assessment of floodplain vulnerability during extreme Mississippi River flood 2011

    USGS Publications Warehouse

    Goodwell, Allison E.; Zhu, Zhenduo; Dutta, Debsunder; Greenberg, Jonathan A.; Kumar, Praveen; Garcia, Marcelo H.; Rhoads, Bruce L.; Holmes, Jr., Robert R.; Parker, Gary; Berretta, David P.; Jacobson, Robert B.

    2014-01-01

    Regional change in the variability and magnitude of flooding could be a major consequence of future global climate change. Extreme floods have the capacity to rapidly transform landscapes and expose landscape vulnerabilities through highly variable spatial patterns of inundation, erosion, and deposition. We use the historic activation of the Birds Point-New Madrid Floodway during the Mississippi and Ohio River Flooding of 2011 as a scientifically unique stress experiment to analyze indicators of floodplain vulnerability. We use pre- and postflood airborne Light Detection and Ranging data sets to locate erosional and depositional hotspots over the 540 km2 agricultural Floodway. While riparian vegetation between the river and the main levee breach likely prevented widespread deposition, localized scour and deposition occurred near the levee breaches. Eroded gullies nearly 1 km in length were observed at a low ridge of a relict meander scar of the Mississippi River. Our flow modeling and spatial mapping analysis attributes this vulnerability to a combination of erodible soils, flow acceleration associated with legacy fluvial landforms, and a lack of woody vegetation to anchor soil and enhance flow resistance. Results from this study could guide future mitigation and adaptation measures in cases of extreme flooding.

  12. Community clusters of tsunami vulnerability in the US Pacific Northwest

    USGS Publications Warehouse

    Wood, Nathan J.; Jones, Jeanne M.; Spielman, Seth; Schmidtlein, Mathew C.

    2015-01-01

    Many coastal communities throughout the world are threatened by local (or near-field) tsunamis that could inundate low-lying areas in a matter of minutes after generation. Although the hazard and sustainability literature often frames vulnerability conceptually as a multidimensional issue involving exposure, sensitivity, and resilience to a hazard, assessments often focus on one element or do not recognize the hazard context. We introduce an analytical framework for describing variations in population vulnerability to tsunami hazards that integrates (i) geospatial approaches to identify the number and characteristics of people in hazard zones, (ii) anisotropic path distance models to estimate evacuation travel times to safety, and (iii) cluster analysis to classify communities with similar vulnerability. We demonstrate this approach by classifying 49 incorporated cities, 7 tribal reservations, and 17 counties from northern California to northern Washington that are directly threatened by tsunami waves associated with a Cascadia subduction zone earthquake. Results suggest three primary community groups: (i) relatively low numbers of exposed populations with varied demographic sensitivities, (ii) high numbers of exposed populations but sufficient time to evacuate before wave arrival, and (iii) moderate numbers of exposed populations but insufficient time to evacuate. Results can be used to enhance general hazard-awareness efforts with targeted interventions, such as education and outreach tailored to local demographics, evacuation training, and/or vertical evacuation refuges.

  13. Enhancement of Aquifer Vulnerability Indexing Using the Analytic Element Method

    NASA Astrophysics Data System (ADS)

    Fredrick, K. C.; Becker, M. W.; Flewelling, D. M.; Silavisesreth, W.

    2003-12-01

    Indexing methods are used for the evaluation of aquifer vulnerability and establishing guidelines for the protection of ground-water resources. The principle of the indexing method is to use map layers of various influences on ground water to determine the overall vulnerability of an aquifer to anthropogenic stresses. The analytic element method (AEM) of ground-water flow modeling can be used to enhance indexing methods by rapidly calculating a potentiometric surface based primarily on surface water features. This potentiometric map can be combined with a digital elevation model to produce a map of depth to the water table. This is an improvement over simple water table interpolation methods because it is physically based and properly represents surface water features, hydraulic boundaries, and changes in hydraulic conductivity. The AEM software, SPLIT, is used in a geographic information system based graphical user interface to improve an aquifer vulnerability assessment for a valley-fill aquifer in western New York State. A GIS-based graphical user interface allows automated conversion of hydrography vector data into analytic elements.

  14. Indicators of hazard, vulnerability and risk in urban drainage.

    PubMed

    Hauger, M B; Mouchel, J M; Mikkelsen, P S

    2006-01-01

    An alternative definition of risk is proposed as risk being a function of the hazard, which is related to the risk source and the vulnerability, which is related to the risk object. The same hazard will not cause the same effect on all risk objects. Therefore, vulnerability is introduced as a system-dependent property to be the link between the hazard and the effect so that the combination of the occurrence of a hazard and the vulnerability of an object results in the effect. In risk communication indicators are helpful since they help to simplify the message that has to be communicated. Three examples (pluvial flooding of sewers, dissolved oxygen depletion in streams and discharge of chemicals to receiving waters) show that dependent on the risk problem possibilities for risk reduction lies either at the risk source or at the risk object. Therefore, it is important to have indicators that can be used when the possibilities of risk reduction are analysed. PMID:17120679

  15. An approach for modeling vulnerability of the network of networks

    NASA Astrophysics Data System (ADS)

    Zhang, Jianhua; Song, Bo; Zhang, Zhaojun; Liu, Haikuan

    2014-10-01

    In this paper, a framework is given to model the network of networks and to investigate the vulnerability of the network of networks subjected to failures. Because there are several redundant systems in infrastructure systems, the dependent intensity between two networks is introduced and adopted to discuss the vulnerability of the interdependent infrastructure networks subjected to failures. Shanghai electrified rail transit network is used to illustrate the feasibility and effectiveness of the proposed framework. Because the rail network is dependent on the power grid and communication network, the corresponding power grid and communication network are also included in this system. Meanwhile the failures to the power grid and communication network are utilized to investigate the vulnerability of the rail network. The results show that the rail network strongly depends on the power grid and weakly depends on the communication network, and the transport functionality loss of the rail network increases with the increase of dependent intensity. Meanwhile the highest betweenness node-based attack to the power grid and the largest degree node-based attack to the communication network can result in the most functionality losses to the rail network. Moreover, the functionality loss of the rail network has the smallest value when the tolerance parameter of the power grid equals 0.75 and the critical nodes of the power grid and communication network can be obtained by simulations.

  16. Rapid Assessment of Seismic Vulnerability in Palestinian Refugee Camps

    NASA Astrophysics Data System (ADS)

    Al-Dabbeek, Jalal N.; El-Kelani, Radwan J.

    Studies of historical and recorded earthquakes in Palestine demonstrate that damaging earthquakes are occurring frequently along the Dead Sea Transform: Earthquake of 11 July 1927 (ML 6.2), Earthquake of 11 February 2004 (ML 5.2). In order to reduce seismic vulnerability of buildings, losses in lives, properties and infrastructures, an attempt was made to estimate the percentage of damage degrees and losses at selected refugee camps: Al Ama`ri, Balata and Dhaishe. Assessing the vulnerability classes of building structures was carried out according to the European Macro-Seismic Scale 1998 (EMS-98) and the Fedral Emergency Management Agency (FEMA). The rapid assessment results showed that very heavy structural and non structural damages will occur in the common buildings of the investigated Refugee Camps (many buildings will suffer from damages grades 4 and 5). Bad quality of buildings in terms of design and construction, lack of uniformity, absence of spaces between the building and the limited width of roads will definitely increase the seismic vulnerability under the influence of moderate-strong (M 6-7) earthquakes in the future.

  17. European information on climate change impacts, vulnerability and adaptation

    NASA Astrophysics Data System (ADS)

    Jol, A.; Isoard, S.

    2010-09-01

    Vulnerability to natural and technological disasters is increasing due to a combination of intensifying land use, increasing industrial development, further urban expansion and expanding infrastructure and also climate change. At EU level the European Commission's White Paper on adaptation to climate change (published in 2009) highlights that adaptation actions should be focused on the most vulnerable areas and communities in Europe (e.g. mountains, coastal areas, river flood prone areas, Mediterranean, Arctic). Mainstreaming of climate change into existing EU policies will be a key policy, including within the Water Framework Directive, Marine Strategy Framework Directive, Nature protection and biodiversity policies, integrated coastal zone management, other (sectoral) policies (agriculture, forestry, energy, transport, health) and disaster risk prevention. 2010 is the international year on biodiversity and the Conference of Parties of the biodiversity convention will meet in autumn 2010 (Japan) to discuss amongst other post-2010 strategies, objectives and indicators. Both within the Biodiversity Convention (CBD) and the Climate Change Convention (UNFCCC) there is increasing recognition of the need for integration of biodiversity conservation into climate change mitigation and adaptation activities. Furthermore a number of European countries and also some regions have started to prepare and/or have adopted national adaptation plans or frameworks. Sharing of good practices on climate change vulnerability methods and adaptation actions is so far limited, but is essential to improve such plans, at national, sub national and local level where much of the adaptation action is already taking place and will be expanding in future, also involving increasingly the business community. The EU Clearinghouse on CC impacts, vulnerability and adaptation should address these needs and it is planned to be operational end of 2011. The EEA is expected to have a role in its development in 2010 and is likely to manage the system after 2011. The European Commission in its Communication in 2009 on disaster risk prevention also calls for improving and better sharing of data on disasters, disaster risk mapping and disaster risk management, in the context of the EU civil protection mechanism. Such information might also be linked to the planned EU Clearinghouse on climate change adaptation. The activities of EEA on climate change impacts, vulnerability and adaptation (including disaster risk reduction) include indicators of the impacts of climate change; a regularly updated overview of national assessments and adaptation plans on the EEA web site and specific focused reports, e.g. on adaptation to the challenges of changing water resources in the Alps (2009) and on analysis of past trends in natural disasters (due in 2010) and regular expert meetings and workshops with EEA member countries. The ECAC presentation will include the latest developments in the EU Clearinghouse on adaptation and progress in relevant EEA activities.

  18. Hydropower and sustainability: resilience and vulnerability in China's powersheds.

    PubMed

    McNally, Amy; Magee, Darrin; Wolf, Aaron T

    2009-07-01

    Large dams represent a whole complex of social, economic and ecological processes, perhaps more than any other large infrastructure project. Today, countries with rapidly developing economies are constructing new dams to provide energy and flood control to growing populations in riparian and distant urban communities. If the system is lacking institutional capacity to absorb these physical and institutional changes there is potential for conflict, thereby threatening human security. In this paper, we propose analyzing sustainability (political, socioeconomic, and ecological) in terms of resilience versus vulnerability, framed within the spatial abstraction of a powershed. The powershed framework facilitates multi-scalar and transboundary analysis while remaining focused on the questions of resilience and vulnerability relating to hydropower dams. Focusing on examples from China, this paper describes the complex nature of dams using the sustainability and powershed frameworks. We then analyze the roles of institutions in China to understand the relationships between power, human security and the socio-ecological system. To inform the study of conflicts over dams China is a particularly useful case study because we can examine what happens at the international, national and local scales. The powershed perspective allows us to examine resilience and vulnerability across political boundaries from a dynamic, process-defined analytical scale while remaining focused on a host of questions relating to hydro-development that invoke drivers and impacts on national and sub-national scales. The ability to disaggregate the affects of hydropower dam construction from political boundaries allows for a deeper analysis of resilience and vulnerability. From our analysis we find that reforms in China's hydropower sector since 1996 have been motivated by the need to create stability at the national scale rather than resilient solutions to China's growing demand for energy and water resource control at the local and international scales. Some measures that improved economic development through the market economy and a combination of dam construction and institutional reform may indeed improve hydro-political resilience at a single scale. However, if China does address large-scale hydropower construction's potential to create multi-scale geopolitical tensions, they may be vulnerable to conflict - though not necessarily violent - in domestic and international political arenas. We conclude with a look toward a resilient basin institution for the Nu/Salween River, the site of a proposed large-scale hydropower development effort in China and Myanmar. PMID:19013007

  19. Spectral CT imaging of vulnerable plaque with two independent biomarkers

    NASA Astrophysics Data System (ADS)

    Baturin, Pavlo; Alivov, Yahya; Molloi, Sabee

    2012-07-01

    The purpose of this paper is to investigate the feasibility of a novel four-material decomposition technique for assessing the vulnerability of plaque with two contrast materials spectral computer tomography (CT) using two independent markers: plaque's inflammation and spotty calcification. A simulation study was conducted using an energy-sensitive photon-counting detector for k-edge imaging of the coronary arteries. In addition to detecting the inflammation status, which is known as a biological marker of a plaque's vulnerability, we use spotty calcium concentration as an independent marker to test a plaque's vulnerability. We have introduced a new method for detecting and quantifying calcium concentrations in the presence of two contrast materials (iodine and gold), calcium and soft tissue background. In this method, four-material decomposition was performed on a pixel-by-pixel basis, assuming there was an arbitrary mixture of materials in the voxel. The concentrations of iodine and gold were determined by the k-edge material decomposition based on the maximum likelihood method. The calibration curves of the attenuation coefficients, with respect to the concentrations of different materials, were used to separate the calcium signal from both contrast materials and different soft tissues in the mixtures. Three different materials (muscle, blood and lipid) were independently used as soft tissue. The simulations included both ideal and more realistic energy resolving detectors to measure the polychromatic photon spectrum in single slice parallel beam geometry. The ideal detector was used together with a 3 cm diameter digital phantom to demonstrate the decomposition method while a more realistic detector and a 33 × 24 cm2 digital chest phantom were simulated to validate the vulnerability assessment technique. A 120 kVp spectrum was generated to produce photon flux sufficient for detecting contrast materials above the k-edges of iodine (33.2 keV) and gold (80.7 keV). By performing simulations on a 3 cm diameter digital phantom, we successfully identified four materials that were simultaneously present in the mixture at different proportions and in multiple locations on the phantom. Quantitative analysis with a chest digital phantom showed that the results for iodine, gold and calcium were highly correlated with the known concentrations. The analysis revealed a potentially powerful technique for assessing a plaque's vulnerability with two independent markers. High correlation and low relative errors between calculated and known materials’ concentrations showed that the method is feasible. This technique can potentially have a high clinical impact.

  20. Epidemiology of health and vulnerability among children orphaned and made vulnerable by HIV/AIDS in sub-Saharan Africa.

    PubMed

    Andrews, Gail; Skinner, Donald; Zuma, Khangelani

    2006-04-01

    The HIV/AIDS epidemic in sub-Saharan Africa has already orphaned a generation of children, and it is projected that by 2010, 18 million African children under the age of 18 are likely to be orphans from this single cause (UNICEF, 2005, The state of the Worlds Children: Childhood under threat. New York: UNICEF). Results from a Kellogg funded OVC project (Skinner et al., 2004, Definition of orphaned and vulnerable children. Cape Town: HSRC) supported the construct that the loss of either or both parents would indicate a situation of likely vulnerability of children. A key problem in the literature on the impact of orphanhood on the well-being of children, families and communities, is that the focus of assertions and predictions is often on the negative impact on 'AIDS orphans', or households. There are hardly any studies that compare the experiences of orphans with non-orphans. This paper thus attempts to fill that gap. It uses epidemiological data to explore the epidemiology of health and vulnerability of children within the context of AIDS in sub-Saharan Africa. Because of data limitations, only the following aspects are examined: (i) orphan status; (ii) household structure (in particular, grandparent headedness and female-headedness); (iii) illness of parents; (iv) poverty; and (v) access to services, especially schooling, health, social services. While recognizing the limitations of the analysis, data presented in this paper indicates that orphans in sub-Saharan Africa are more vulnerable than non-orphans. The authors conclude with some suggestions for policy makers and programme implementers, highlighting the importance of focusing on interventions that will have maximum impact on the health and well-being of children. PMID:16546789

  1. Do official hospitalizations predict medical vulnerability among the homeless?: a postdictive validity study of the vulnerability index.

    PubMed

    Cronley, Courtney; Petrovich, James; Spence-Almaguer, Emily; Preble, Kathleen

    2013-05-01

    The current study tested the postdictive validity of the Vulnerability Index (VI), an instrument used to assess medical vulnerability among people who are homeless. It also examined the relationship between hospitalization records and self-reported health status. The VI is based on self-reports of hospital utilization and chronic health conditions. Data were collected over a one-year period from individuals receiving homeless services in a southwestern city (N = 97, 53.3% male, 57.7% African American). Vulnerability Index scores and three subcomponents of the measure (chronic health conditions, substance use, and mental health problems) were regressed on official reports of past-year hospitalizations, controlling for gender and race, using four separate regression models. Official hospitalization records significantly predicted overall VI scores, but they did not predict the subcomponents of the measure. Results show that, within the current sample, official hospital records are predictive of overall VI scores and are correlated with self-reported hospitalization. The lack of relationship between hospital records and subcomponents of the VI may indicate an underutilization of health care for those with serious health conditions. PMID:23728023

  2. The arctic water resource vulnerability index: An integrated assessment tool for community resilience and vulnerability with respect to freshwater

    USGS Publications Warehouse

    Alessa, L.; Kliskey, A.; Lammers, R.; Arp, C.; White, D.; Hinzman, L.; Busey, R.

    2008-01-01

    People in the Arctic face uncertainty in their daily lives as they contend with environmental changes at a range of scales from local to global. Freshwater is a critical resource to people, and although water resource indicators have been developed that operate from regional to global scales and for midlatitude to equatorial environments, no appropriate index exists for assessing the vulnerability of Arctic communities to changing water resources at the local scale. The Arctic Water Resource Vulnerability Index (AWRVI) is proposed as a tool that Arctic communities can use to assess their relative vulnerability-resilience to changes in their water resources from a variety of biophysical and socioeconomic processes. The AWRVI is based on a social-ecological systems perspective that includes physical and social indicators of change and is demonstrated in three case study communities/watersheds in Alaska. These results highlight the value of communities engaging in the process of using the AWRVI and the diagnostic capability of examining the suite of constituent physical and social scores rather than the total AWRVI score alone. ?? 2008 Springer Science+Business Media, LLC.

  3. Putting vulnerability to climate change on the map: a review of approaches, benefits, and risks

    SciTech Connect

    Preston, Benjamin L

    2011-01-01

    There is growing demand among stakeholders across public and private institutions for spatially-explicit information regarding vulnerability to climate change at the local scale. However, the challenges associated with mapping the geography of climate change vulnerability are non-trivial, both conceptually and technically, suggesting the need for more critical evaluation of this practice. Here, we review climate change vulnerability mapping in the context of four key questions that are fundamental to assessment design. First, what are the goals of the assessment? A review of published assessments yields a range of objective statements that emphasize problem orientation or decision-making about adaptation actions. Second, how is the assessment of vulnerability framed? Assessments vary with respect to what values are assessed (vulnerability of what) and the underlying determinants of vulnerability that are considered (vulnerability to what). The selected frame ultimately influences perceptions of the primary driving forces of vulnerability as well as preferences regarding management alternatives. Third, what are the technical methods by which an assessment is conducted? The integration of vulnerability determinants into a common map remains an emergent and subjective practice associated with a number of methodological challenges. Fourth, who participates in the assessment and how will it be used to facilitate change? Assessments are often conducted under the auspices of benefiting stakeholders, yet many lack direct engagement with stakeholders. Each of these questions is reviewed in turn by drawing on an illustrative set of 45 vulnerability mapping studies appearing in the literature. A number of pathways for placing vulnerability

  4. Assessment Model of Ecoenvironmental Vulnerability Based on Improved Entropy Weight Method

    PubMed Central

    Zhang, Xianqi; Wang, Chenbo; Li, Enkuan; Xu, Cundong

    2014-01-01

    Assessment of ecoenvironmental vulnerability plays an important role in the guidance of regional planning, the construction and protection of ecological environment, which requires comprehensive consideration on regional resources, environment, ecology, society and other factors. Based on the driving mechanism and evolution characteristics of ecoenvironmental vulnerability in cold and arid regions of China, a novel evaluation index system on ecoenvironmental vulnerability is proposed in this paper. For the disadvantages of conventional entropy weight method, an improved entropy weight assessment model on ecoenvironmental vulnerability is developed and applied to evaluate the ecoenvironmental vulnerability in western Jilin Province of China. The assessing results indicate that the model is suitable for ecoenvironmental vulnerability assessment, and it shows more reasonable evaluation criterion, more distinct insights and satisfactory results combined with the practical conditions. The model can provide a new method for regional ecoenvironmental vulnerability evaluation. PMID:25133260

  5. Age-Related Psychophysiological Vulnerability to Phenylalanine in Phenylketonuria

    PubMed Central

    Leuzzi, Vincenzo; Mannarelli, Daniela; Manti, Filippo; Pauletti, Caterina; Locuratolo, Nicoletta; Carducci, Carla; Carducci, Claudia; Vanacore, Nicola; Fattapposta, Francesco

    2014-01-01

    Background: Phenylketonuria (PKU) is caused by the inherited defect of the phenylalanine hydroxylase enzyme, which converts phenylalanine (Phe) into tyrosine (Tyr). Neonatal screening programs and early treatment have radically changed the natural history of PKU. Nevertheless, an increased risk of neurocognitive and psychiatric problems in adulthood remains a challenging aspect of the disease. In order to assess the vulnerability of complex skills to Phe, we explored: (a) the effect of a rapid increase in blood Phe levels on event-related potentials (ERP) in PKU subjects during their second decade of life; (b) the association (if existing) between psychophysiological and neurocognitive features. Methods: Seventeen early-treated PKU subjects, aged 10–20, underwent ERP [mismatch negativity, auditory P300, contingent negative variation (CNV), and Intensity Dependence of Auditory Evoked Potentials] recording before and 2 h after an oral loading of Phe. Neurocognitive functioning, historical and concurrent biochemical values of blood Phe, Tyr, and Phe/Tyr ratio, were all included in the statistical analysis. Results: Event-related potential components were normally detected in all the subjects. In subjects younger than 13 CNV amplitude, W2-CNV area, P3b latency, and reaction times in motor responses were negatively influenced by Phe-loading. Independently from the psychophysiological vulnerability, some neurocognitive skills were more impaired in younger patients. No correlation was found between biochemical alterations and neurocognitive and psychophysiological findings. Conclusion: The vulnerability of the emerging neurocognitive functions to Phe suggests a strict metabolic control in adolescents affected by PKU and a neurodevelopmental approach in the study of neurocognitive outcome in PKU. PMID:25003100

  6. Approaches of Seismic Vulnerability Assessments in Near Real Time Systems

    NASA Astrophysics Data System (ADS)

    Frolova, Nina; Larionov, Valery; Bonnin, Jean; Ugarov, Alexander

    2014-05-01

    Data on seismic vulnerability of existing building stock and other elements at risk are rather important for near real time earthquake loss estimations by global systems. These data together with information on regional peculiarities of seismic intensity attenuation and other factors contribute greatly to the reliability of strong event consequences estimated in emergency mode. There are different approaches for vulnerability functions' development and the empirical one is most often used. It is based on analysis of engineering consequences of past strong events when well documented descriptions of damage to different building types and other elements at risk are available for the earthquake prone area under consideration. In the case such data do not exist the information from macroseismic scales may be used. Any approach of vulnerability functions' development requires the proper classification of buildings and structures under consideration. According to national and international building codes, as well as macroseismic scales different buildings' classifications exist. As a result the global systems, such as Extremum and PAGER, as well as GEM project make use of the non-unified information on building stock distribution worldwide. The paper addresses the issues of buildings' classification and city models in terms of these classifications. Distribution of different buildings types in Extremum and PAGER/GEM systems is analyzed for earthquake prone countries. The comparison of city models revealed significant differences which influence greatly earthquake loss estimations in emergency mode. The paper describes the practice of city models' development which make use of space images and web technology in social networks. It is proposed to use the G8 country (and other) initiatives related to open data and transparency aimed at improving building stock distribution and global population databases.

  7. Brain renin-angiotensin system and dopaminergic cell vulnerability

    PubMed Central

    Labandeira-García, Jose L.; Garrido-Gil, Pablo; Rodriguez-Pallares, Jannette; Valenzuela, Rita; Borrajo, Ana; Rodríguez-Perez, Ana I.

    2014-01-01

    Although the renin-angiotensin system (RAS) was classically considered as a circulating system that regulates blood pressure, many tissues are now known to have a local RAS. Angiotensin, via type 1 receptors, is a major activator of the NADPH-oxidase complex, which mediates several key events in oxidative stress (OS) and inflammatory processes involved in the pathogenesis of major aging-related diseases. Several studies have demonstrated the presence of RAS components in the basal ganglia, and particularly in the nigrostriatal system. In the nigrostriatal system, RAS hyperactivation, via NADPH-oxidase complex activation, exacerbates OS and the microglial inflammatory response and contributes to progression of dopaminergic degeneration, which is inhibited by angiotensin receptor blockers and angiotensin converting enzyme (ACE) inhibitors. Several factors may induce an increase in RAS activity in the dopaminergic system. A decrease in dopaminergic activity induces compensatory upregulation of local RAS function in both dopaminergic neurons and glia. In addition to its role as an essential neurotransmitter, dopamine may also modulate microglial inflammatory responses and neuronal OS via RAS. Important counterregulatory interactions between angiotensin and dopamine have also been observed in several peripheral tissues. Neurotoxins and proinflammatory factors may also act on astrocytes to induce an increase in RAS activity, either independently of or before the loss of dopamine. Consistent with a major role of RAS in dopaminergic vulnerability, increased RAS activity has been observed in the nigra of animal models of aging, menopause and chronic cerebral hypoperfusion, which also showed higher dopaminergic vulnerability. Manipulation of the brain RAS may constitute an effective neuroprotective strategy against dopaminergic vulnerability and progression of Parkinson’s disease. PMID:25071471

  8. Socio-Economic Vulnerability to Climate Change in California

    NASA Astrophysics Data System (ADS)

    Heberger, M. G.; Cooley, H.; Moore, E.; Garzon, C.

    2011-12-01

    The western United States faces a range of impacts from global climate change, including increases in extreme heat, wildfires, and coastal flooding and erosion; changes are also likely to occur in air quality, water availability, and the spread of infectious diseases. To date, a great deal of research has been done to forecast the physical effects of climate change, while less attention has been given to the factors make different populations more or less vulnerable to harm from such changes. For example, mortality rates from Hurricane Audrey, which struck the coast of Louisiana in 1957, were more than eight times higher among blacks than among whites. While disaster events may not discriminate, impacts on human populations are shaped by "intervening conditions" that determine the human impact of the flood and the specific needs for preparedness, response, and recovery. In this study, we analyze the potential impacts of climate change by using recent downscaled climate model outputs, creating a variety of statistics and visualizations to communicate potential impacts to community groups and decision makers, after several meetings with these groups to ask, "What types of information are most useful to you for planning?" We relate climate impacts to social vulnerability - defined as the intersection of the exposure, sensitivity, and adaptive capacity of a person or group of people - with a focus on the U.S. state of California. Understanding vulnerability factors and the populations that exhibit these factors are critical for crafting effective climate change policies and response strategies. It is also important to the emerging study of climate justice, which is the concept that no group of people should disproportionately bear the burden of climate impacts or the costs of mitigation and adaptation.

  9. Vulnerable yet agentic: independent child migrants and opportunity structures.

    PubMed

    Orgocka, Aida

    2012-01-01

    While agency and vulnerability have been central organizing concepts in analyzing independent child migration, studying these in isolation from the opportunity structures that define it provides only a partial picture of its occurrence. In introducing the five contributions to this volume, this chapter argues that agentic capacities emerge and interact across a spectrum of contextual influences that may undermine or promote these. Although most contributions offer insight from forced migration, they illustrate the fluidity of migration processes in general. This chapter also calls to move beyond compartmentalized approaches and oversimplified structural categories such as chronological age to describe independent child migration. PMID:22689520

  10. Multispectral optoacoustic tomography resolves smart probe activation in vulnerable plaques

    NASA Astrophysics Data System (ADS)

    Razansky, Daniel; Harlaar, Niels J.; Hillebrands, Jan-Luuk; Taruttis, Adrian; Herzog, Eva; Zeebregts, Clark; van Dam, Goitzen; Ntziachristos, Vasilis

    2011-03-01

    In this work, we show, for the first time to our knowledge, that multispectral optoacoustic tomography (MSOT) can deliver high resolution images of activatable molecular probe's distribution, sensitive to matrix metalloproteinases (MMP), deep within optically scattering human carotid specimen. It is further demonstrated that this method can be used in order to provide accurate maps of vulnerable plaque formations in atherosclerotic disease. Moreover, optoacoustic images can simultaneously show the underlining plaque morphology for accurate localization of MMP activity in three dimensions. This performance directly relates to small animal screening applications and to clinical potential as well.

  11. Emerging Approaches for Targeting Metabolic Vulnerabilities in Malignant Glioma.

    PubMed

    Clark, Peter M; Mai, Wilson X; Cloughesy, Timothy F; Nathanson, David A

    2016-02-01

    Malignant gliomas are intractable and among the most lethal human malignancies. Like other cancers, metabolic reprogramming is a key feature of glioma and is thought to accommodate the heightened nutrient requirements for tumor cell proliferation, growth, and survival. This metabolic rewiring, driven by oncogenic signaling and molded by the unique environment of the brain, may impose vulnerabilities that could be exploited therapeutically for increased tumor control. In this review, we discuss the prominent metabolic features of malignant glioma, the key pathways regulating glioma metabolism, and the potential therapeutic opportunities for targeting metabolic processes. PMID:26759318

  12. Electronic equipment vulnerability to fire released carbon fibers

    NASA Technical Reports Server (NTRS)

    Pride, R. A.; Mchatton, A. D.; Musselman, K. A.

    1980-01-01

    The vulnerability of electronic equipment to damage by carbon fibers released from burning aircraft type structural composite materials was investigated. Tests were conducted on commercially available stereo power amplifiers which showed that the equipment was damaged by fire released carbon fibers but not by the composite resin residue, soot and products of combustion of the fuel associated with burning the carbon fiber composites. Results indicate that the failure rates of the equipment exposed to the fire released fiber were consistent with predictions based on tests using virgin fibers.

  13. Disaster management: vulnerability and resilience in disaster recovery in Thailand.

    PubMed

    Busapathumrong, Pattamaporn

    2013-01-01

    This project explores disaster management in Thailand with a focus on the vulnerability and resilience of women, children, the elderly, and the disabled population and on the impact of disaster on these subpopulations. The 2 main findings deal with the major models of disaster management in Thailand and building resilience for social recovery. The selected 5 major models currently employed in disaster management in Thailand are the (a) model of royal project and international cooperation on disaster preparedness and response, (b) ASEAN Socio-Cultural Blueprint, (c) rights-based approach, (d) welfare mix model, and (e) knowledge management model. PMID:23679805

  14. Water vulnerabilities for existing coal-fired power plants.

    SciTech Connect

    Elcock, D.; Kuiper, J.; Environmental Science Division

    2010-08-19

    This report was funded by the U.S. Department of Energy's (DOE's) National Energy Technology Laboratory (NETL) Existing Plants Research Program, which has an energy-water research effort that focuses on water use at power plants. This study complements the Existing Plants Research Program's overall research effort by evaluating water issues that could impact power plants. Water consumption by all users in the United States over the 2005-2030 time period is projected to increase by about 7% (from about 108 billion gallons per day [bgd] to about 115 bgd) (Elcock 2010). By contrast, water consumption by coal-fired power plants over this period is projected to increase by about 21% (from about 2.4 to about 2.9 bgd) (NETL 2009b). The high projected demand for water by power plants, which is expected to increase even further as carbon-capture equipment is installed, combined with decreasing freshwater supplies in many areas, suggests that certain coal-fired plants may be particularly vulnerable to potential water demand-supply conflicts. If not addressed, these conflicts could limit power generation and lead to power disruptions or increased consumer costs. The identification of existing coal-fired plants that are vulnerable to water demand and supply concerns, along with an analysis of information about their cooling systems and related characteristics, provides information to help focus future research and development (R&D) efforts to help ensure that coal-fired generation demands are met in a cost-effective manner that supports sustainable water use. This study identified coal-fired power plants that are considered vulnerable to water demand and supply issues by using a geographical information system (GIS) that facilitated the analysis of plant-specific data for more than 500 plants in the NETL's Coal Power Plant Database (CPPDB) (NETL 2007a) simultaneously with 18 indicators of water demand and supply. Two types of demand indicators were evaluated. The first type consisted of geographical areas where specific conditions can generate demand vulnerabilities. These conditions include high projected future water consumption by thermoelectric power plants, high projected future water consumption by all users, high rates of water withdrawal per square mile (mi{sup 2}), high projected population increases, and areas projected to be in a water crisis or conflict by 2025. The second type of demand indicator was plant specific. These indicators were developed for each plant and include annual water consumption and withdrawal rates and intensities, net annual power generation, and carbon dioxide (CO{sub 2}) emissions. The supply indictors, which are also area based, include areas with low precipitation, high temperatures, low streamflow, and drought. The indicator data, which were in various formats (e.g., maps, tables, raw numbers) were converted to a GIS format and stored, along with the individual plant data from the CPPDB, in a single GIS database. The GIS database allowed the indicator data and plant data to be analyzed and visualized in any combination. To determine the extent to which a plant would be considered 'vulnerable' to a given demand or supply concern (i.e., that the plant's operations could be affected by water shortages represented by a potential demand or supply indicator), criteria were developed to categorize vulnerability according to one of three types: major, moderate, or not vulnerable. Plants with at least two major demand indicator values and/or at least four moderate demand indicator values were considered vulnerable to demand concerns. By using this approach, 144 plants were identified as being subject to demand concerns only. Plants with at least one major supply indicator value and/or at least two moderate supply indicator values were considered vulnerable to supply concerns. By using this approach, 64 plants were identified as being subject to supply concerns only. In addition, 139 plants were identified as subject to both demand and supply concerns. Therefore, a total of 347 plants were considered subject to demand concerns, supply concerns, or both demand and supply concerns.

  15. Rare Species Support Vulnerable Functions in High-Diversity Ecosystems

    PubMed Central

    Mouillot, David; Bellwood, David R.; Baraloto, Christopher; Chave, Jerome; Galzin, Rene; Harmelin-Vivien, Mireille; Kulbicki, Michel; Lavergne, Sebastien; Lavorel, Sandra; Mouquet, Nicolas; Paine, C. E. Timothy; Renaud, Julien; Thuiller, Wilfried

    2013-01-01

    Around the world, the human-induced collapses of populations and species have triggered a sixth mass extinction crisis, with rare species often being the first to disappear. Although the role of species diversity in the maintenance of ecosystem processes has been widely investigated, the role of rare species remains controversial. A critical issue is whether common species insure against the loss of functions supported by rare species. This issue is even more critical in species-rich ecosystems where high functional redundancy among species is likely and where it is thus often assumed that ecosystem functioning is buffered against species loss. Here, using extensive datasets of species occurrences and functional traits from three highly diverse ecosystems (846 coral reef fishes, 2,979 alpine plants, and 662 tropical trees), we demonstrate that the most distinct combinations of traits are supported predominantly by rare species both in terms of local abundance and regional occupancy. Moreover, species that have low functional redundancy and are likely to support the most vulnerable functions, with no other species carrying similar combinations of traits, are rarer than expected by chance in all three ecosystems. For instance, 63% and 98% of fish species that are likely to support highly vulnerable functions in coral reef ecosystems are locally and regionally rare, respectively. For alpine plants, 32% and 89% of such species are locally and regionally rare, respectively. Remarkably, 47% of fish species and 55% of tropical tree species that are likely to support highly vulnerable functions have only one individual per sample on average. Our results emphasize the importance of rare species conservation, even in highly diverse ecosystems, which are thought to exhibit high functional redundancy. Rare species offer more than aesthetic, cultural, or taxonomic diversity value; they disproportionately increase the potential breadth of functions provided by ecosystems across spatial scales. As such, they are likely to insure against future uncertainty arising from climate change and the ever-increasing anthropogenic pressures on ecosystems. Our results call for a more detailed understanding of the role of rarity and functional vulnerability in ecosystem functioning. PMID:23723735

  16. Structural vulnerability assessment using reliability of slabs in avalanche area

    NASA Astrophysics Data System (ADS)

    Favier, Philomène; Bertrand, David; Eckert, Nicolas; Naaim, Mohamed

    2013-04-01

    Improvement of risk assessment or hazard zoning requires a better understanding of the physical vulnerability of structures. To consider natural hazard issue such as snow avalanches, once the flow is characterized, highlight on the mechanical behaviour of the structure is a decisive step. A challenging approach is to quantify the physical vulnerability of impacted structures according to various avalanche loadings. The main objective of this presentation is to introduce methodology and outcomes regarding the assessment of vulnerability of reinforced concrete buildings using reliability methods. Reinforced concrete has been chosen as it is one of the usual material used to build structures exposed to potential avalanche loadings. In avalanche blue zones, structures have to resist to a pressure up to 30kPa. Thus, by providing systematic fragility relations linked to the global failure of the structure, this method may serve the avalanche risk assessment. To do so, a slab was numerically designed. It represented the avalanche facing wall of a house. Different configuration cases of the element in stake have been treated to quantify numerical aspects of the problem, such as the boundary conditions or the mechanical behaviour of the structure. The structure is analysed according to four different limit states, semi-local and global failures are considered to describe the slab behaviour. The first state is attained when cracks appear in the tensile zone, then the two next states are described consistent with the Eurocode, the final state is the total collapse of the structure characterized by the yield line theory. Failure probability is estimated in accordance to the reliability framework. Monte Carlo simulations were conducted to quantify the fragility to different loadings. Sensitivity of models in terms of input distributions were defined with statistical tools such as confidence intervals and Sobol's indexes. Conclusion and discussion of this work are established to well determine contributions, limits and future needs or developments of the research. First of all, this study provides spectrum of fragility curves of reinforced concrete structures which could be used to improve risk assessment. Second, the influence of the failure criterion picked up in this survey are discussed. Then, the weight of the statistical distribution choice is analysed. Finally, the limit between vulnerability and fragility relations is set up to establish the boundary use of our approach.

  17. Rare species support vulnerable functions in high-diversity ecosystems.

    PubMed

    Mouillot, David; Bellwood, David R; Baraloto, Christopher; Chave, Jerome; Galzin, Rene; Harmelin-Vivien, Mireille; Kulbicki, Michel; Lavergne, Sebastien; Lavorel, Sandra; Mouquet, Nicolas; Paine, C E Timothy; Renaud, Julien; Thuiller, Wilfried

    2013-01-01

    Around the world, the human-induced collapses of populations and species have triggered a sixth mass extinction crisis, with rare species often being the first to disappear. Although the role of species diversity in the maintenance of ecosystem processes has been widely investigated, the role of rare species remains controversial. A critical issue is whether common species insure against the loss of functions supported by rare species. This issue is even more critical in species-rich ecosystems where high functional redundancy among species is likely and where it is thus often assumed that ecosystem functioning is buffered against species loss. Here, using extensive datasets of species occurrences and functional traits from three highly diverse ecosystems (846 coral reef fishes, 2,979 alpine plants, and 662 tropical trees), we demonstrate that the most distinct combinations of traits are supported predominantly by rare species both in terms of local abundance and regional occupancy. Moreover, species that have low functional redundancy and are likely to support the most vulnerable functions, with no other species carrying similar combinations of traits, are rarer than expected by chance in all three ecosystems. For instance, 63% and 98% of fish species that are likely to support highly vulnerable functions in coral reef ecosystems are locally and regionally rare, respectively. For alpine plants, 32% and 89% of such species are locally and regionally rare, respectively. Remarkably, 47% of fish species and 55% of tropical tree species that are likely to support highly vulnerable functions have only one individual per sample on average. Our results emphasize the importance of rare species conservation, even in highly diverse ecosystems, which are thought to exhibit high functional redundancy. Rare species offer more than aesthetic, cultural, or taxonomic diversity value; they disproportionately increase the potential breadth of functions provided by ecosystems across spatial scales. As such, they are likely to insure against future uncertainty arising from climate change and the ever-increasing anthropogenic pressures on ecosystems. Our results call for a more detailed understanding of the role of rarity and functional vulnerability in ecosystem functioning. PMID:23723735

  18. Rethinking vulnerability analysis and governance with emphasis on a participatory approach.

    PubMed

    Rossignol, Nicolas; Delvenne, Pierre; Turcanu, Catrinel

    2015-01-01

    This article draws on vulnerability analysis as it emerged as a complement to classical risk analysis, and it aims at exploring its ability for nurturing risk and vulnerability governance actions. An analysis of the literature on vulnerability analysis allows us to formulate a three-fold critique: first, vulnerability analysis has been treated separately in the natural and the technological hazards fields. This separation prevents vulnerability from unleashing the full range of its potential, as it constrains appraisals into artificial categories and thus already closes down the outcomes of the analysis. Second, vulnerability analysis focused on assessment tools that are mainly quantitative, whereas qualitative appraisal is a key to assessing vulnerability in a comprehensive way and to informing policy making. Third, a systematic literature review of case studies reporting on participatory approaches to vulnerability analysis allows us to argue that participation has been important to address the above, but it remains too closed down in its approach and would benefit from embracing a more open, encompassing perspective. Therefore, we suggest rethinking vulnerability analysis as one part of a dynamic process between opening-up and closing-down strategies, in order to support a vulnerability governance framework. PMID:24924802

  19. Does the new EU Regulation on clinical trials adequately protect vulnerable research participants?

    PubMed

    Gennet, Éloïse; Andorno, Roberto; Elger, Bernice

    2015-07-01

    Vulnerable research participants deserve special protection because of their increased risks of being wronged. Yet, paradoxically, the conduct of trials involving vulnerable groups is sometimes inescapable to develop safe and efficient therapies suitable to these groups. The key question is therefore how to protect vulnerable research participants from harm and exploitation without excluding the populations they belong to from the benefits of research. The European Union faced this challenge in April 2014 when adopting the new Regulation on clinical trials, which will replace the currently applicable 2001 Clinical Trials Directive in 2016. In order to assess the protection of vulnerable persons in the new Regulation, this paper makes four suggestions: first, the need to adopt a risk-based approach to vulnerability in biomedical research; second, to better distinguish between decisional vulnerabilities and health-related vulnerabilities; third, to emphasise the need to preserve the freedom of consent of subjects with decisional vulnerability, who are more susceptible to undue influence; and finally to assert the need of actively promoting specific clinical trials involving people with physical or psychological vulnerabilities. In conclusion, this paper claims that the protection of vulnerable subjects still needs to be improved in the new EU Regulation. PMID:25951954

  20. Comparison and Evaluation of Global Scale Studies of Vulnerability and Risks to Climate Change

    NASA Astrophysics Data System (ADS)

    Muccione, Veruska; Allen, Simon K.; Huggel, Christian; Birkmann, Joern

    2015-04-01

    Understanding the present and future distribution of different climate change impacts and vulnerability to climate change is a central subject in the context of climate justice and international climate policy. Commonly, it is claimed that poor countries that contributed little to anthropogenic climate change are those most affected and most vulnerable to climate change. Such statements are backed by a number of global-scale vulnerability studies, which identified poor countries as most vulnerable. However, some studies have challenged this view, likewise highlighting the high vulnerability of richer countries. Overall, no consensus has been reached so far about which concept of vulnerability should be applied and what type of indicators should be considered. Furthermore, there is little agreement which specific countries are most vulnerable. This is a major concern in view of the need to inform international climate policy, all the more if such assessments should contribute to allocate climate adaptation funds as was invoked at some instances. We argue that next to the analysis of who is most vulnerable, it is also important to better understand and compare different vulnerability profiles assessed in present global studies. We perform a systematic literature review of global vulnerability assessments with the scope to highlight vulnerability distribution patterns. We then compare these distributions with global risk distributions in line with revised and adopted concepts by most recent IPCC reports. It emerges that improved differentiation of key drivers of risk and the understanding of different vulnerability profiles are important contributions, which can inform future adaptation policies at the regional and national level. This can change the perspective on, and basis for distributional issues in view of climate burden share, and therefore can have implications for UNFCCC financing instruments (e.g. Green Climate Fund). However, in order to better compare traditional vulnerability distributions with more recent conceptualisation of risks, more research should be devoted to global assessments of climate change risk distributions.

  1. Regional risk assessment for contaminated sites part 1: vulnerability assessment by multicriteria decision analysis.

    PubMed

    Zabeo, A; Pizzol, L; Agostini, P; Critto, A; Giove, S; Marcomini, A

    2011-11-01

    As highlighted in the EU Soil Communication, local contamination is one of the main soil threats and it is often related to present and past industrial activities which left a legacy of a high number of contaminated sites in Europe. These contaminated sites can be harmful to many different receptors according to their sensitivity/susceptibility to contamination, and specific vulnerability evaluations are needed in order to manage this widely spread environmental issue. In this paper a novel comprehensive vulnerability assessment framework to assess regional receptor susceptibility to contaminated site is presented. The developed methodology, which combines multi criteria decision analysis (MCDA) techniques and spatial analysis, can be applied to different receptors recognized as relevant for regional assessment. In order to characterize each receptor, picked parameters significant for the estimation of the vulnerability to contaminated sites have been selected, normalized and aggregated by means of multi criteria decision analysis (MCDA) techniques. The developed MCDA methodology, based on the Choquet integral, allows to include expert judgments for the elicitation of synergic and conflicting effects between involved criteria and is applied to all the geographical objects representing the identified receptors. To test the potential of the vulnerability methodology, it has been applied to a specific case study area in the upper Silesia region of Poland where it proved to be reliable and consistent with the environmental experts' expected results. The vulnerability assessment results indicate that groundwater is the most vulnerable receptor characterized by a wide area with vulnerability scores belonging to the highest vulnerability class. As far as the other receptors are concerned, human health and surface water are characterized by quite homogeneous vulnerability scores falling in the medium-high vulnerability classes, while protected areas resulted to be the less vulnerable receptor with only one protected area falling in the medium vulnerability class. The vulnerability assessment results will support the regional risk assessment for the ranking of potentially contaminated sites at regional scale. PMID:21723609

  2. Assessing mechanical vulnerability in water distribution networks under multiple failures

    NASA Astrophysics Data System (ADS)

    Berardi, Luigi; Ugarelli, Rita; Røstum, Jon; Giustolisi, Orazio

    2014-03-01

    Understanding mechanical vulnerability of water distribution networks (WDN) is of direct relevance for water utilities since it entails two different purposes. On the one hand, it might support the identification of severe failure scenarios due to external causes (e.g., natural or intentional events) which result into the most critical consequences on WDN supply capacity. On the other hand, it aims at figure out the WDN portions which are more prone to be affected by asset disruptions. The complexity of such analysis stems from the number of possible scenarios with single and multiple simultaneous shutdowns of asset elements leading to modifications of network topology and insufficient water supply to customers. In this work, the search for the most disruptive combinations of multiple asset failure events is formulated and solved as a multiobjective optimization problem. The higher vulnerability failure scenarios are detected as those causing the lower supplied demand due to the lower number of simultaneous failures. The automatic detection of WDN topology, subsequent to the detachments of failed elements, is combined with pressure-driven analysis. The methodology is demonstrated on a real water distribution network. Results show that, besides the failures causing the detachment of reservoirs, tanks, or pumps, there are other different topological modifications which may cause severe WDN service disruptions. Such information is of direct relevance to support planning asset enhancement works and improve the preparedness to extreme events.

  3. Vulnerability of cloud forest reserves in Mexico to climate change

    NASA Astrophysics Data System (ADS)

    Ponce-Reyes, Rocío; Reynoso-Rosales, Víctor-Hugo; Watson, James E. M.; Vanderwal, Jeremy; Fuller, Richard A.; Pressey, Robert L.; Possingham, Hugh P.

    2012-06-01

    Tropical montane cloud forests are among the most vulnerable terrestrial ecosystems to climate change owing to their restricted climatic requirements and their narrow and fragmented distribution. Although 12% of Mexican cloud forest is protected, it is not known whether reserves will ensure the persistence of the ecosystem and its endemic species under climate change. Here, we show that 68% of Mexico's cloud forest could vanish by 2080 because of climate change and more than 90% of cloud forest that is protected at present will not be climatically suitable for that ecosystem in 2080. Moreover, if we assume unprotected forests are cleared, 99% of the entire ecosystem could be lost through a combination of climate change and habitat loss, resulting in the extinction of about 70% of endemic cloud forest vertebrate species. Immediate action is required to minimize this loss--expansion of the protected-area estate in areas of low climate vulnerability is an urgent priority. Our analysis indicates that one key area for immediate protection is the Sierra de Juárez in Oaxaca. This area supports many endemic species and is expected to retain relatively large fragments of cloud forest despite rapid climate change.

  4. Vulnerability of ecosystems to climate change moderated by habitat intactness.

    PubMed

    Eigenbrod, Felix; Gonzalez, Patrick; Dash, Jadunandan; Steyl, Ilse

    2015-01-01

    The combined effects of climate change and habitat loss represent a major threat to species and ecosystems around the world. Here, we analyse the vulnerability of ecosystems to climate change based on current levels of habitat intactness and vulnerability to biome shifts, using multiple measures of habitat intactness at two spatial scales. We show that the global extent of refugia depends highly on the definition of habitat intactness and spatial scale of the analysis of intactness. Globally, 28% of terrestrial vegetated area can be considered refugia if all natural vegetated land cover is considered. This, however, drops to 17% if only areas that are at least 50% wilderness at a scale of 48×48 km are considered and to 10% if only areas that are at least 50% wilderness at a scale of 4.8×4.8 km are considered. Our results suggest that, in regions where relatively large, intact wilderness areas remain (e.g. Africa, Australia, boreal regions, South America), conservation of the remaining large-scale refugia is the priority. In human-dominated landscapes, (e.g. most of Europe, much of North America and Southeast Asia), focusing on finer scale refugia is a priority because large-scale wilderness refugia simply no longer exist. Action to conserve such refugia is particularly urgent since only 1 to 2% of global terrestrial vegetated area is classified as refugia and at least 50% covered by the global protected area network. PMID:25059822

  5. Salt vulnerability assessment methodology for municipal supply wells

    NASA Astrophysics Data System (ADS)

    Betts, Andrew; Gharabaghi, Bahram; McBean, Ed; Levison, Jana; Parker, Beth

    2015-12-01

    De-icing agents containing chloride ions used for winter road maintenance have the potential to negatively impact groundwater resources for drinking water supplies. A novel methodology using commonly-available geospatial data (land use, well head protection areas) and public accessible data (salt application rates, hydrometric data) to identify salt vulnerable areas (SVAs) for groundwater wells is developed to prioritize implementation of better management practices for road salt applications. The approach uses simple mass-balance terms to collect chloride input from 3 pathways: surface runoff, shallow interflow and baseflow. A risk score is calculated, which depends on the land use within the respective municipal supply well protection area. Therefore, it is plausible to avoid costly and extensive numerical modeling (which also would bear many assumptions, simplifications and uncertainties). The method is applied to perform a vulnerability assessment on twenty municipal water supply wells in the Grand River watershed, Ontario, Canada. The calculated steady-state groundwater recharge chloride concentration for the supply wells is strongly correlated to the measured transient groundwater chloride concentrations in the case study evaluation, with an R2 = 0.84. The new method provides a simple, robust, and practical method for municipalities to assess the long-term risk of chloride contamination of municipal supply wells due to road salt application.

  6. Major depression during interferon-α treatment: vulnerability and prevention

    PubMed Central

    Lotrich, Francis E.

    2009-01-01

    Major Depressive Disorder (MDD) during interferons (IFN-α) treatment can occur within a few months of therapy, and shares many homologies with other forms of MDD, Most patients are resilient to the side effect ofinterferon-induced depression (IFN-MDD), but 15% to 40% are vulnerable. Several studies have employed antidepressants to prevent the incidence of an IFN-MDD episode, and the results suggest that prophylactic antidepressants may be specifically useful in those with pre-existing subthreshold depressive symptoms andlor a history of prior MDD episodes. Several other potential markers of vulnerability for IFN-MDD have been implicated in assessments of nondepressed patients before they start IFN-α These include poor sleep quality, premorbid elevations in inflammatory cytokines, genetic polymorphisms in the serotonin system, personality, and social support. The interplay of these factors strongly predicts who is at risk for IFN-MDD, and indicates several potentially modifiable targets for the personalized prevention of IFN-MDD, PMID:20135899

  7. Emotional vulnerability and coping styles for resolving decisional conflict.

    PubMed

    Umeh, Kanayo; Omari-Asor, Lorraine

    2011-01-01

    This investigation supplements the study by D. Bouckenooghe, K. Vanderheyden, S. Mestdagh, and S. van Laethem (2007) on the role of cognitive dispositions in coping patterns for resolving decisional conflict. Literature suggests emotional vulnerabilities may significantly affect decision making. Thus, the present authors assessed the role of trait anxiety and depression in decision coping styles as specified by I. L. Janis and L. Mann's (1977) conflict-theory model. The participants--100 young adults--completed the Taylor Manifest Anxiety Scale (J. A. Taylor, 1953), Beck's Depression Inventory (A. T. Beck, R. A. Steer, & G. M. Garbin, 1988), and the Melbourne Decision-Making Questionnaire (L. Mann et al., 1998), which measures 4 coping strategies: vigilance, buck-passing, procrastination, and hypervigilance. Hierarchical multiple regression analysis, controlling for demographic and lifestyle factors, revealed trait anxiety and depression as significant predictors of procrastination and hypervigilance. Depression failed to predict buck-passing but functioned as an important moderator variable whereby trait anxiety better predicted hypervigilance in nondepressed participants. Consistent with past research, emotional dispositions failed to predict vigilance. Overall, these findings implicate emotional vulnerabilities in the quality of decision making but raise important questions about their unique and conditional effects. PMID:21834323

  8. Researching the vulnerables: issues of consent and ethical approval.

    PubMed

    Afolabi, M O S

    2012-12-01

    Imagine you are a biomedical scientist attempting to cross a busy, beggar-crowded road in Lagos. You suddenly notice that the loud horns of the speeding cars, trucks and trailers draw no visible physiologic response from any of the beggars including their children and babies, unlike the rest of the crowd. Consequently, certain questions such as the following begin to engage your mind: Is this phenomenon a kind of habituation? If so, is its onset the same for the blind ones amongst them? Have these beggars acquired a neural system absent from "normal" people? If so, just how long does it take for such a system to be established? At the very height of this creative outburst, you however realize that the informed consent and ethical approval you would need for this particular research differs from the type you have previously encountered in your career.... Although the above scenario suggests that new and difficult ethical questions may confront scientists while pursuing their curiosity, our research ethics guidelines do not currently address this issue. This paper explores some of the ethical challenges involved in carrying out basic research on vulnerable subjects such as beggars. It highlights how the notions of autonomy and informed consent in this context become vague, thus, liable to exploitation. Ultimately, the paper offers a useful framework in relation to developing a research ethics committee charged with the moral mandate of overseeing the integrity of research involving this vulnerable population in particular and basic biomedical research in general. PMID:23678631

  9. A Methodology for Assessing the Seismic Vulnerability of Highway Systems

    SciTech Connect

    Cirianni, Francis; Leonardi, Giovanni; Scopelliti, Francesco

    2008-07-08

    Modern society is totally dependent on a complex and articulated infrastructure network of vital importance for the existence of the urban settlements scattered on the territory. On these infrastructure systems, usually indicated with the term lifelines, are entrusted numerous services and indispensable functions of the normal urban and human activity.The systems of the lifelines represent an essential element in all the urbanised areas which are subject to seismic risk. It is important that, in these zones, they are planned according to opportune criteria based on two fundamental assumptions: a) determination of the best territorial localization, avoiding, within limits, the places of higher dangerousness; b) application of constructive technologies finalized to the reduction of the vulnerability.Therefore it is indispensable that in any modern process of seismic risk assessment the study of the networks is taken in the rightful consideration, to be integrated with the traditional analyses of the buildings.The present paper moves in this direction, dedicating particular attention to one kind of lifeline: the highway system, proposing a methodology of analysis finalized to the assessment of the seismic vulnerability of the system.

  10. Does inadequate sleep play a role in vulnerability to obesity?

    PubMed Central

    Knutson, Kristen L.

    2011-01-01

    The prevalence of obesity is increasing rapidly worldwide, which is cause for concern because obesity increases the risk of cardiovascular disease and diabetes, reduces life expectancy and impairs quality of life. A better understanding of the risk factors for obesity is therefore a critical global health concern and human biologists can play an important role in identifying these risk factors in various populations. The objective of this review is to present the evidence that inadequate sleep may be a novel risk factor associated with increased vulnerability to obesity and associated cardiometabolic disease. Experimental studies have found that short-term sleep restriction is associated with impaired glucose metabolism, dysregulation of appetite and increased blood pressure. Observational studies have observed cross-sectional associations between short sleep duration (generally <6 hours per night) and increased body mass index or obesity, prevalent diabetes and prevalent hypertension. Some studies also reported an association between self-reported long sleep duration (generally >8 hours per night) and cardiometabolic disease. A few prospective studies have found a significant increased risk of weight gain, incident diabetes and incident hypertension associated with inadequate sleep. Given the potential link between inadequate sleep and obesity, a critical next step is to identify the social, cultural and environmental determinants of sleep, which would help to identify vulnerable populations. Future human biology research should consider variation in sleep characteristics among different populations and determine whether the associations between sleep and obesity observed in Western populations persist elsewhere. PMID:22275135

  11. Climate Change, Health, and Vulnerability in Canadian Northern Aboriginal Communities

    PubMed Central

    Furgal, Christopher; Seguin, Jacinthe

    2006-01-01

    Background Canada has recognized that Aboriginal and northern communities in the country face unique challenges and that there is a need to expand the assessment of vulnerabilities to climate change to include these communities. Evidence suggests that Canada’s North is already experiencing significant changes in its climate—changes that are having negative impacts on the lives of Aboriginal people living in these regions. Research on climate change and health impacts in northern Canada thus far has brought together Aboriginal community members, government representatives, and researchers and is charting new territory. Methods and Results In this article we review experiences from two projects that have taken a community-based dialogue approach to identifying and assessing the effects of and vulnerability to climate change and the impact on the health in two Inuit regions of the Canadian Arctic. Conclusions The results of the two case projects that we present argue for a multi-stakeholder, participatory framework for assessment that supports the necessary analysis, understanding, and enhancement of capabilities of local areas to respond and adapt to the health impacts at the local level. PMID:17185292

  12. Initiation of reentry inside the vulnerable window of the heart

    NASA Astrophysics Data System (ADS)

    Baudenbacher, Petra; Baudenbacher, Franz; Aliev, Rubin; Wikswo, John

    2000-03-01

    Cardiac vulnerability refers to the initiation of self-sustained waves after the application of a stimulus in the wake of a propagating pulse, which can lead to arrhythmias and fibrillation. We used optical mapping of the transmembrane potential on the epicardium of Langendorff-perfused, di-4-ANNEPS stained isolated rabbit hearts. After a planar wave was launched by an S1 stimulus with line electrodes perpendicular to the fiber direction, an S2 stimulus was applied with a point electrode at a different location at a time ?T after S1. The S1 strength was 2-4×threshold S2=2×S1. The spatio-temporal dynamics of S2 responses shows three distinct excitation regions: For ?T>160ms, a point shaped hypopolarized region (make excitation) leads to propagation symmetrical in both directions perpendicular to the wire. For ?T<160ms, a dog-bone shaped hyperpolarized region is followed by a hypopolarized region (break excitation), leading to an asymmetrical curved wave due to partial functional block, and in some cases reentry, especially at shorter time intervals. For ?T<115ms, break excitation occurs without propagation. Stimulating inside the vulnerable window results in multiple responses due to functional block and allows us to extract the propagation velocity as a function of refractoriness.

  13. A conceptual model of people's vulnerability to floods

    NASA Astrophysics Data System (ADS)

    Milanesi, Luca; Pilotti, Marco; Ranzi, Roberto

    2015-01-01

    Hydraulic risk maps provide the baseline for land use and emergency planning. Accordingly, they should convey clear information on the potential physical implications of the different hazards to the stakeholders. This paper presents a vulnerability criterion focused on human stability in a flow specifically devised for rapidly evolving floods where life, before than economic values, might be threatened. The human body is conceptualized as a set of cylinders and its stability to slipping and toppling is assessed by forces and moments equilibrium. Moreover, a depth threshold to consider drowning is assumed. In order to widen its scope of application, the model takes the destabilizing effect of local slope (so far disregarded in the literature) and fluid density into account. The resulting vulnerability classification could be naturally subdivided in three levels (low, medium, and high) that are limited by two stability curves for children and adults, respectively. In comparison with the most advanced literature conceptual approaches, the proposed model is weakly parameterized and the computed thresholds fit better the available experimental data sets. A code that implements the proposed algorithm is provided.

  14. Ethical considerations in research. Focus on vulnerable groups.

    PubMed

    Ketefian, Shaké

    2015-01-01

    The purpose of this paper was to describe the need to protect the rights of human subjects participating in nursing research, and procedures for doing so. The path taken to the task at hand was to approach the topic by discussing the philosophical underpinnings of human subject protection and describing the approach for doing this in all cases where humans are used as research subjects. These underpinnings include specific ethical principles of respect for persons, beneficence, and justice, and the procedures used in the U.S. for protecting the rights of human subjects. Once the process was clarified, the considerations necessary to protect the special groups referred to as ''vulnerable'' are discussed. Given the author's access to U.S. documents and the fact that U.S. government agencies took early steps to formalize rules and regulations for the protection of human subjects, vulnerable or otherwise, the experience of the United States was selected for presentation. It is recognized that there are now relevant international documents that are exceedingly helpful, and also, that various countries may have their own guidelines for investigators to follow. In such cases researchers can engage in comparative analysis between their own guidance and the processes described here, and decide their path accordingly. PMID:26148168

  15. Cyclone disaster vulnerability and response experiences in coastal Bangladesh.

    PubMed

    Alam, Edris; Collins, Andrew E

    2010-10-01

    For generations, cyclones and tidal surges have frequently devastated lives and property in coastal and island Bangladesh. This study explores vulnerability to cyclone hazards using first-hand coping recollections from prior to, during and after these events. Qualitative field data suggest that, beyond extreme cyclone forces, localised vulnerability is defined in terms of response processes, infrastructure, socially uneven exposure, settlement development patterns, and livelihoods. Prior to cyclones, religious activities increase and people try to save food and valuable possessions. Those in dispersed settlements who fail to reach cyclone shelters take refuge in thatched-roof houses and big-branch trees. However, women and children are affected more despite the modification of traditional hierarchies during cyclone periods. Instinctive survival strategies and intra-community cooperation improve coping post cyclone. This study recommends that disaster reduction programmes encourage cyclone mitigation while being aware of localised realities, endogenous risk analyses, and coping and adaptation of affected communities (as active survivors rather than helpless victims). PMID:20561338

  16. Does topological information matter for power grid vulnerability?

    NASA Astrophysics Data System (ADS)

    Ouyang, Min; Yang, Kun

    2014-12-01

    Power grids, which are playing an important role in supporting the economy of a region as well as the life of its citizens, could be attacked by terrorists or enemies to damage the region. Depending on different levels of power grid information collected by the terrorists, their attack strategies might be different. This paper groups power grid information into four levels: no information, purely topological information (PTI), topological information with generator and load nodes (GLNI), and full information (including component physical properties and flow parameters information), and then identifies possible attack strategies for each information level. Analyzing and comparing power grid vulnerability under these attack strategies from both terrorists' and utility companies' point of view give rise to an approach to quantify the relative values of these three types of information, including PTI, GLNI, and component parameter information (CPI). This approach can provide information regarding the extent to which topological information matters for power system vulnerability decisions. Taking several test systems as examples, results show that for small attacks with p ? 0.1, CPI matters the most; when taking attack cost into consideration and assuming that the terrorists take the optimum cost-efficient attack intensity, then CPI has the largest cost-based information value.

  17. Does topological information matter for power grid vulnerability?

    PubMed

    Ouyang, Min; Yang, Kun

    2014-12-01

    Power grids, which are playing an important role in supporting the economy of a region as well as the life of its citizens, could be attacked by terrorists or enemies to damage the region. Depending on different levels of power grid information collected by the terrorists, their attack strategies might be different. This paper groups power grid information into four levels: no information, purely topological information (PTI), topological information with generator and load nodes (GLNI), and full information (including component physical properties and flow parameters information), and then identifies possible attack strategies for each information level. Analyzing and comparing power grid vulnerability under these attack strategies from both terrorists' and utility companies' point of view give rise to an approach to quantify the relative values of these three types of information, including PTI, GLNI, and component parameter information (CPI). This approach can provide information regarding the extent to which topological information matters for power system vulnerability decisions. Taking several test systems as examples, results show that for small attacks with p???0.1, CPI matters the most; when taking attack cost into consideration and assuming that the terrorists take the optimum cost-efficient attack intensity, then CPI has the largest cost-based information value. PMID:25554041

  18. Distinguishing adaptive plasticity from vulnerability in the aging hippocampus.

    PubMed

    Gray, D T; Barnes, C A

    2015-11-19

    Hippocampal circuits are among the best described networks in the mammalian brain, particularly with regard to the alterations that arise during normal aging. Decades of research indicate multiple points of vulnerability in aging neural circuits, and it has been proposed that each of these changes make a contribution to observed age-related cognitive deficits. Another view has been relatively overlooked - namely that some of these changes arise in adaptive response to protect network function in aged animals. This possibility leads to a rather different view on the biological variation of function in the brain of older individuals. Using the hippocampus as a model neural circuit we discuss how, in normally aged animals, some age-related changes may arise through processes of neural plasticity that serve to enhance network function rather than to hinder it. Conceptually disentangling the initial age-related vulnerabilities from changes that result in adaptive response will be a major challenge for the future research on brain aging. We suggest that a reformulation of how normal aging could be understood from an adaptive perspective will lead to a deeper understanding of the secrets behind successful brain aging and our recent cultural successes in facilitating these processes. PMID:26255677

  19. Public Health Consequences on Vulnerable Populations from Acute Chemical Releases

    PubMed Central

    Ruckart, Perri Zeitz; Orr, Maureen F.

    2008-01-01

    Data from a large, multi-state surveillance system on acute chemical releases were analyzed to describe the type of events that are potentially affecting vulnerable populations (children, elderly and hospitalized patients) in order to better prevent and plan for these types of incidents in the future. During 2003–2005, there were 231 events where vulnerable populations were within ¼ mile of the event and the area of impact was greater than 200 feet from the facility/point of release. Most events occurred on a weekday during times when day care centers or schools were likely to be in session. Equipment failure and human error caused a majority of the releases. Agencies involved in preparing for and responding to chemical emergencies should work with hospitals, nursing homes, day care centers, and schools to develop policies and procedures for initiating appropriate protective measures and managing the medical needs of patients. Chemical emergency response drills should involve the entire community to protect those that may be more susceptible to harm. PMID:21572842

  20. Midwifery care of poor and vulnerable women, 1925-2003.

    PubMed

    Raisler, Jeanne; Kennedy, Holly

    2005-01-01

    A systematic literature review of research on midwifery care of poor and vulnerable women from 1925 to 2003, which included topics studied, research methods used, and special issues and implications for future research, was performed; 44 studies published between 1955 and 2003 were identified. The majority were retrospective, descriptive studies. Outcomes examined included prenatal care visits, vaginal versus operative births, labor interventions, maternal and neonatal mortality and morbidity, birth weight, and cost-effectiveness. Studies showed that midwives predominantly serve vulnerable women who are young, poor, immigrants, or members of racial and ethnic minorities. Preterm birth prevention is emerging as a midwifery research focus. Health system changes are making it more difficult to provide effective care and counseling to disadvantaged women, especially in managed care settings. Extensive evidence documents excellent outcomes of midwifery care for the poor in urban and rural settings over the past three quarters of a century. Future research should include more intervention studies and use both qualitative and quantitative methods to investigate midwifery processes of care and the process-outcome connection. The research focus should broaden beyond childbirth to include gynecology, family planning, and primary care issues. Health disparities, cultural studies, obstetric interventions, and poor women's experiences of childbirth and midwifery care are important topics for future research. PMID:15749297

  1. Vulnerability of settlements around Mt. Cameroon volcano, Cameroon

    NASA Astrophysics Data System (ADS)

    Zogning, Appolinaire; Spinetti, Claudia; Ngouanet, Chretien; Tchoudam, David; Kouokam, Emmanuel; Thierry, Pierre; Bignami, Christian; Fabrizia Buongiorno, Maria; Ilaria Pannaccione Apa, Maria

    2010-05-01

    Located at the bottom of the Gulf of Guinea, Cameroon is exposed to a large variety of natural hazards, including volcanism. Most of the hazard are concentrated around the active volcano Mt. Cameroon which combines effusive and explosive types of activity. The threatened stakes are numerous and different exposed: people, settlements, industrial plantations, petrol refinery and many other factories and infrastructures. Until 2005, no risk management plans has been available. In 2006, the French Embassy in Cameroon, within the framework of a financial convention between Cameroon and France, put in place the GRINP (Management of Natural Risks and Civil Protection) project whose objective was to reinforce the capacity of Cameroon's civil protection department and thus, contribute to the improvement of the security of the population faced with catastrophes. The objective was to realize a Risk Prevention Plan at a local council scale, and taking into consideration the specific natural risks of each zone. The general objective of the RPP was to clearly draw land use maps for risks zones, showing the overlay of stakes with risk of different intensities. In 2008 European Commission funded the Mia-Vita project (Mitigating and Assessing Volcanic Impacts on Terrain and human Activities). The aim of the project is to improve the crisis management capabilities based on monitoring and early warning systems and secure communications; reduction of people's vulnerability and development of recovering capabilities after an event occurs for both local communities and ecological systems. Keyword: natural hazards, Mt. Cameroon, vulnerability, risk prevention plan

  2. Field information links permafrost carbon to physical vulnerabilities of thawing

    USGS Publications Warehouse

    Harden, Jennifer W.; Koven, Charles; Ping, Chien-Lu; Hugelius, Gustaf; McGuire, A. David; Camill, P.; Jorgenson, Torre; Kuhry, Peter; Michaelson, Gary; O'Donnell, Jonathan A.; Schuur, Edward A.G.; Tamocai, Charles; Johnson, K.; Grosse, G.

    2012-01-01

    Deep soil profiles containing permafrost (Gelisols) were characterized for organic carbon (C) and total nitrogen (N) stocks to 3m depths. Using the Community Climate System Model (CCSM4) we calculate cumulative probability functions (PDFs) for active layer depths under current and future climates. The difference in PDFs over time was multiplied by C and N contents of soil horizons in Gelisol suborders to calculate newly thawed C and N, Thawing ranged from 147 PgC with 10 PgN by 2050 (representative concentration pathway RCP scenario 4.5) to 436 PgC with 29 PgN by 2100 (RCP 8.5). Organic horizons that thaw are vulnerable to combustion, and all horizon types are vulnerable to shifts in hydrology and decomposition. The rates and extent of such losses are unknown and can be further constrained by linking field and modelling approaches. These changes have the potential for strong additional loading to our atmosphere, water resources, and ecosystems.

  3. The Vulnerability of Threatened Species: Adaptive Capability and Adaptation Opportunity

    PubMed Central

    Berry, Pam; Ogawa-Onishi, Yuko; McVey, Andrew

    2013-01-01

    Global targets to halt the loss of biodiversity have not been met, and there is now an additional Aichi target for preventing the extinction of known threatened species and improving their conservation status. Climate change increasingly needs to be factored in to these, and thus there is a need to identify the extent to which it could increase species vulnerability. This paper uses the exposure, sensitivity, and adaptive capacity framework to assess the vulnerability of a selection of WWF global priority large mammals and marine species to climate change. However, it divides adaptive capacity into adaptive capability and adaptation opportunity, in order to identify whether adaptation is more constrained by the biology of the species or by its environmental setting. Lack of evidence makes it difficult to apply the framework consistently across the species, but it was found that, particularly for the terrestrial mammals, adaptation opportunities seems to be the greater constraint. This framework and analysis could be used by conservationists and those wishing to enhance the resilience of species to climate change. PMID:24833051

  4. Optical coherence tomography for imaging the vulnerable plaque

    NASA Astrophysics Data System (ADS)

    Tearney, Guillermo J.; Jang, Ik-Kyung; Bouma, Brett E.

    2006-03-01

    While our understanding of vulnerable coronary plaque is still at an early stage, the concept that certain types of plaques predispose patients to developing an acute myocardial infarction continues to be at the forefront of cardiology research. Intracoronary optical coherence tomography (OCT) has been developed to both identify and study these lesions due to its distinct resolution advantage over other imaging modalities. We review clinical research conducted at the Massachusetts General Hospital over the past five years to develop, validate, and utilize this technology to improve our understanding of vulnerable plaque. Our results show that intracoronary OCT may be safely conducted in patients and that it provides abundant information regarding plaque microscopic morphology, which is essential to the identification and study of high-risk lesions. Even though many basic biological, clinical, and technological challenges must be addressed prior to widespread use of this technology, the unique capabilities of OCT ensure that it will have a prominent role in shaping the future of cardiology.

  5. Seismic vulnerability and risk assessment of Kolkata City, India

    NASA Astrophysics Data System (ADS)

    Nath, S. K.; Adhikari, M. D.; Devaraj, N.; Maiti, S. K.

    2014-04-01

    The city of Kolkata is one of the most urbanized and densely populated regions in the world, which is a major industrial and commercial hub of the Eastern and Northeastern region of India. In order to classify the seismic risk zones of Kolkata we used seismic hazard exposures on the vulnerability components namely, landuse/landcover, population density, building typology, age and height. We microzoned seismic hazard of the City by integrating seismological, geological and geotechnical themes in GIS which in turn is integrated with the vulnerability components in a logic-tree framework to estimate both the socio-economic and structural risk of the City. In both the risk maps, three broad zones have been demarcated as "severe", "high" and "moderate". There had also been a risk-free zone in the City. The damage distribution in the City due to the 1934 Bihar-Nepal Earthquake of Mw 8.1 well matches with the risk regime. The design horizontal seismic coefficients for the City have been worked out for all the predominant periods which indicate suitability of "A", "B" and "C" type of structures. The cumulative damage probabilities in terms of "slight", "moderate", "extensive" and "complete" have also been assessed for the significant four model building types viz. RM2L, RM2M, URML and URMM for each structural seismic risk zone in the City. Both the Seismic Hazard and Risk maps are expected to play vital roles in the earthquake inflicted disaster mitigation and management of the city of Kolkata.

  6. Cognitive Mechanisms Reciprocally Transmit Vulnerability between Depressive and Somatic Symptoms

    PubMed Central

    Harding, Kaitlin A.; Murphy, Karly M.

    2015-01-01

    Despite high comorbidity between depressive and somatic symptoms, cognitive mechanisms that transmit vulnerability between symptom clusters are largely unknown. Dampening, positive rumination, and brooding are three cognitive predictors of depression, with rumination theoretically indicated as a transdiagnostic vulnerability through amplifying and diminishing affect in response to events. Specifically, the excess negative affect and lack of positive affect characteristic of depressive symptoms and underlying somatic symptoms may cause and be caused by cognitive responses to events. Therefore, the current study examined whether comorbidity between depressive and somatic symptoms may be explained by the cognitive mechanisms of dampening and positive rumination in response to positive events and brooding in response to negative events among adults (N = 321) across eight weeks of assessment. We hypothesized that greater dampening and brooding would reciprocally predict greater depressive and somatic symptoms, while greater positive rumination would reciprocally predict fewer depressive and somatic symptoms. Mediation analyses in AMOS 22 indicated that dampening and brooding mediated reciprocal pathways between depressive and somatic symptoms, but positive rumination did not. Findings propose dampening and brooding as mechanisms of the reciprocal relationship between depressive and somatic symptoms through diminishing positive affect and amplifying negative affect in response to positive and negative events. PMID:26783455

  7. Seismic vulnerability study Los Alamos Meson Physics Facility (LAMPF)

    SciTech Connect

    Salmon, M.; Goen, L.K.

    1995-12-01

    The Los Alamos Meson Physics Facility (LAMPF), located at TA-53 of Los Alamos National Laboratory (LANL), features an 800 MeV proton accelerator used for nuclear physics and materials science research. As part of the implementation of DOE Order 5480.25 and in preparation for DOE Order 5480.28, a seismic vulnerability study of the structures, systems, and components (SSCs) supporting the beam line from the accelerator building through to the ends of die various beam stops at LAMPF has been performed. The study was accomplished using the SQUG GIP methodology to assess the capability of the various SSCs to resist an evaluation basis earthquake. The evaluation basis earthquake was selected from site specific seismic hazard studies. The goals for the study were as follows: (1) identify SSCs which are vulnerable to seismic loads; and (2) ensure that those SSCs screened during die evaluation met the performance goals required for DOE Order 5480.28. The first goal was obtained by applying the SQUG GIP methodology to those SSCS represented in the experience data base. For those SSCs not represented in the data base, information was gathered and a significant amount of engineering judgment applied to determine whether to screen the SSC or to classify it as an outlier. To assure the performance goals required by DOE Order 5480.28 are met, modifications to the SQUG GIP methodology proposed by Salmon and Kennedy were used. The results of this study ire presented in this paper.

  8. Chronic Stress, Drug Use, and Vulnerability to Addiction

    PubMed Central

    Sinha, Rajita

    2009-01-01

    Stress is a well-known risk factor in the development of addiction and in addiction relapse vulnerability. A series of population-based and epidemiological studies have identified specific stressors and individual-level variables that are predictive of substance use and abuse. Preclinical research also shows that stress exposure enhances drug self-administration and reinstates drug seeking in drug-experienced animals. The deleterious effects of early life stress, child maltreatment, and accumulated adversity on alterations in the corticotropin releasing factor and hypothalamic-pituitary-adrenal axis (CRF/HPA), the extrahypothalamic CRF, the autonomic arousal, and the central noradrenergic systems are also presented. The effects of these alterations on the corticostriatal-limbic motivational, learning, and adaptation systems that include mesolimbic dopamine, glutamate, and gamma-amino-butyric acid (GABA) pathways are discussed as the underlying pathophysiology associated with stress-related risk of addiction. The effects of regular and chronic drug use on alterations in these stress and motivational systems are also reviewed, with specific attention to the impact of these adaptations on stress regulation, impulse control, and perpetuation of compulsive drug seeking and relapse susceptibility. Finally, research gaps in furthering our understanding of the association between stress and addiction are presented, with the hope that addressing these unanswered questions will significantly influence new prevention and treatment strategies to address vulnerability to addiction. PMID:18991954

  9. Exposing asymmetric gray matter vulnerability in amyotrophic lateral sclerosis

    PubMed Central

    Devine, Matthew S.; Pannek, Kerstin; Coulthard, Alan; McCombe, Pamela A.; Rose, Stephen E.; Henderson, Robert D.

    2015-01-01

    Limb weakness in amyotrophic lateral sclerosis (ALS) is typically asymmetric. Previous studies have identified an effect of limb dominance on onset and spread of weakness, however relative atrophy of dominant and non-dominant brain regions has not been investigated. Our objective was to use voxel-based morphometry (VBM) to explore gray matter (GM) asymmetry in ALS, in the context of limb dominance. 30 ALS subjects were matched with 17 healthy controls. All subjects were right-handed. Each underwent a structural MRI sequence, from which GM segmentations were generated. Patterns of GM atrophy were assessed in ALS subjects with first weakness in a right-sided limb (n = 15) or left-sided limb (n = 15). Within each group, a voxelwise comparison was also performed between native and mirror GM images, to identify regions of hemispheric GM asymmetry. Subjects with ALS showed disproportionate atrophy of the dominant (left) motor cortex hand area, irrespective of the side of first limb weakness (p < 0.01). Asymmetric atrophy of the left somatosensory cortex and temporal gyri was only observed in ALS subjects with right-sided onset of limb weakness. Our VBM protocol, contrasting native and mirror images, was able to more sensitively detect asymmetric GM pathology in a small cohort, compared with standard methods. These findings indicate particular vulnerability of dominant upper limb representation in ALS, supporting previous clinical studies, and with implications for cortical organisation and selective vulnerability. PMID:25844330

  10. Application of Satellite Gravimetry for Water Resource Vulnerability Assessment

    NASA Technical Reports Server (NTRS)

    Rodell, Matthew

    2012-01-01

    The force of Earth's gravity field varies in proportion to the amount of mass near the surface. Spatial and temporal variations in the gravity field can be measured via their effects on the orbits of satellites. The Gravity Recovery and Climate Experiment (GRACE) is the first satellite mission dedicated to monitoring temporal variations in the gravity field. The monthly gravity anomaly maps that have been delivered by GRACE since 2002 are being used to infer changes in terrestrial water storage (the sum of groundwater, soil moisture, surface waters, and snow and ice), which are the primary source of gravity variability on monthly to decadal timescales after atmospheric and oceanic circulation effects have been removed. Other remote sensing techniques are unable to detect water below the first few centimeters of the land surface. Conventional ground based techniques can be used to monitor terrestrial water storage, but groundwater, soil moisture, and snow observation networks are sparse in most of the world, and the countries that do collect such data rarely are willing to share them. Thus GRACE is unique in its ability to provide global data on variations in the availability of fresh water, which is both vital to life on land and vulnerable to climate variability and mismanagement. This chapter describes the unique and challenging aspects of GRACE terrestrial water storage data, examples of how the data have been used for research and applications related to fresh water vulnerability and change, and prospects for continued contributions of satellite gravimetry to water resources science and policy.

  11. Chemical Safety Vulnerability Working Group report. Volume 3

    SciTech Connect

    Not Available

    1994-09-01

    The Chemical Safety Vulnerability (CSV) Working Group was established to identify adverse conditions involving hazardous chemicals at DOE facilities that might result in fires or explosions, release of hazardous chemicals to the environment, or exposure of workers or the public to chemicals. A CSV Review was conducted in 148 facilities at 29 sites. Eight generic vulnerabilities were documented related to: abandoned chemicals and chemical residuals; past chemical spills and ground releases; characterization of legacy chemicals and wastes; disposition of legacy chemicals; storage facilities and conditions; condition of facilities and support systems; unanalyzed and unaddressed hazards; and inventory control and tracking. Weaknesses in five programmatic areas were also identified related to: management commitment and planning; chemical safety management programs; aging facilities that continue to operate; nonoperating facilities awaiting deactivation; and resource allocations. Volume 3 consists of eleven appendices containing the following: Field verification reports for Idaho National Engineering Lab., Rocky Flats Plant, Brookhaven National Lab., Los Alamos National Lab., and Sandia National Laboratories (NM); Mini-visits to small DOE sites; Working Group meeting, June 7--8, 1994; Commendable practices; Related chemical safety initiatives at DOE; Regulatory framework and industry initiatives related to chemical safety; and Chemical inventory data from field self-evaluation reports.

  12. Treatment during a vulnerable developmental period rescues a genetic epilepsy.

    PubMed

    Marguet, Stephan Lawrence; Le-Schulte, Vu Thao Quyen; Merseburg, Andrea; Neu, Axel; Eichler, Ronny; Jakovcevski, Igor; Ivanov, Anton; Hanganu-Opatz, Ileana Livia; Bernard, Christophe; Morellini, Fabio; Isbrandt, Dirk

    2015-12-01

    The nervous system is vulnerable to perturbations during specific developmental periods. Insults during such susceptible time windows can have long-term consequences, including the development of neurological diseases such as epilepsy. Here we report that a pharmacological intervention timed during a vulnerable neonatal period of cortical development prevents pathology in a genetic epilepsy model. By using mice with dysfunctional Kv7 voltage-gated K(+) channels, which are mutated in human neonatal epilepsy syndromes, we demonstrate the safety and efficacy of the sodium-potassium-chloride cotransporter NKCC1 antagonist bumetanide, which was administered during the first two postnatal weeks. In Kv7 current-deficient mice, which normally display epilepsy, hyperactivity and stereotypies as adults, transient bumetanide treatment normalized neonatal in vivo cortical network and hippocampal neuronal activity, prevented structural damage in the hippocampus and restored wild-type adult behavioral phenotypes. Furthermore, bumetanide treatment did not adversely affect control mice. These results suggest that in individuals with disease susceptibility, timing prophylactically safe interventions to specific windows during development may prevent or arrest disease progression. PMID:26594844

  13. The Occurrence and Prevention of Foodborne Disease in Vulnerable People

    PubMed Central

    O'Brien, Sarah J.

    2011-01-01

    Abstract In developed countries, such as the United Kingdom and the United States, between 15% and 20% of the population show greater susceptibility than the general population to foodborne disease. This proportion includes people with primary immunodeficiency, patients treated with radiation or with immunosuppressive drugs for cancer and diseases of the immune system, those with acquired immune-deficiency syndrome and diabetics, people suffering from liver or kidney disease or with excessive iron in the blood, pregnant women, infants, and the elderly. Malnutrition and use of antacids, particularly proton-pump inhibitors, also increase susceptibility. We review the occurrence of infection by foodborne pathogens in these groups of people and measures to prevent infection. The nature and use of low microbial diets to reduce the risk of foodborne disease in immunocompromised patients are very variable. Diets for vulnerable people in care should exclude higher-risk foods, and vulnerable people in the community should receive clear advice about food safety, in particular avoidance of higher-risk foods and substitution of safer, nutritious foods. PMID:21561383

  14. Vessel maturation schedule determines vulnerability to neuronal injuries of prematurity

    PubMed Central

    Licht, Tamar; Dor-Wollman, Talia; Ben-Zvi, Ayal; Rothe, Gadiel; Keshet, Eli

    2015-01-01

    Premature birth is a major risk factor for multiple brain pathologies, notably periventricular leukomalacia (PVL), which is distinguished by bilateral necrosis of neural tissue around the ventricles and a sequela of neurological disturbances. The 2 hallmarks of brain pathologies of prematurity are a restricted gestational window of vulnerability and confinement of injury to a specific cerebral region. Here, we examined the proposition that both of these features are determined by the state of blood vessel immaturity. We developed a murine genetic model that allows for inducible and reversible VEGF blockade during brain development. Using this system, we determined that cerebral vessels mature in a centrifugal, wave-like fashion that results in sequential acquisition of a functional blood-brain barrier and exit from a VEGF-dependent phase, with periventricular vessels being the last to mature. This developmental program permitted selective ablation of periventricular vessels via episodic VEGF blockade within a specific, vulnerable gestational window. Enforced collapse of ganglionic eminence vessels and resultant periventricular neural apoptosis resulted in a PVL-like phenotype that recapitulates the primary periventricular lesion, ventricular enlargement, and the secondary cortical deficit in out-migrating GABAergic inhibitory interneurons. These findings provide an animal model that reproduces the temporal and spatial specificities of PVL and indicate that damage to VEGF-dependent, immature periventricular vessels contributes to PVL development. PMID:25689256

  15. Chemical Safety Vulnerability Working Group report. Volume 2

    SciTech Connect

    Not Available

    1994-09-01

    The Chemical Safety Vulnerability (CSV) Working Group was established to identify adverse conditions involving hazardous chemicals at DOE facilities that might result in fires or explosions, release of hazardous chemicals to the environment, or exposure of workers or the public to chemicals. A CSV Review was conducted in 148 facilities at 29 sites. Eight generic vulnerabilities were documented related to: abandoned chemicals and chemical residuals; past chemical spills and ground releases; characterization of legacy chemicals and wastes; disposition of legacy chemicals; storage facilities and conditions; condition of facilities and support systems; unanalyzed and unaddressed hazards; and inventory control and tracking. Weaknesses in five programmatic areas were also identified related to: management commitment and planning; chemical safety management programs; aging facilities that continue to operate; nonoperating facilities awaiting deactivation; and resource allocations. Volume 2 consists of seven appendices containing the following: Tasking memorandums; Project plan for the CSV Review; Field verification guide for the CSV Review; Field verification report, Lawrence Livermore National Lab.; Field verification report, Oak Ridge Reservation; Field verification report, Savannah River Site; and the Field verification report, Hanford Site.

  16. Seismic Vulnerability and Performance Level of confined brick walls

    SciTech Connect

    Ghalehnovi, M.; Rahdar, H. A.

    2008-07-08

    There has been an increase on the interest of Engineers and designers to use designing methods based on displacement and behavior (designing based on performance) Regarding to the importance of resisting structure design against dynamic loads such as earthquake, and inability to design according to prediction of nonlinear behavior element caused by nonlinear properties of constructional material.Economically speaking, easy carrying out and accessibility of masonry material have caused an enormous increase in masonry structures in villages, towns and cities. On the other hand, there is a necessity to study behavior and Seismic Vulnerability in these kinds of structures since Iran is located on the earthquake belt of Alpide.Different reasons such as environmental, economic, social, cultural and accessible constructional material have caused different kinds of constructional structures.In this study, some tied walls have been modeled with software and with relevant accelerator suitable with geology conditions under dynamic analysis to research on the Seismic Vulnerability and performance level of confined brick walls. Results from this analysis seem to be satisfactory after comparison of them with the values in Code ATC40, FEMA and standard 2800 of Iran.

  17. Applying a Comprehensive Contextual Climate Change Vulnerability Framework to New Zealand's Tourism Industry.

    PubMed

    Hopkins, Debbie

    2015-03-01

    Conceptualisations of 'vulnerability' vary amongst scholarly communities, contributing to a wide variety of applications. Research investigating vulnerability to climate change has often excluded non-climatic changes which may contribute to degrees of vulnerability perceived or experienced. This paper introduces a comprehensive contextual vulnerability framework which incorporates physical, social, economic and political factors which could amplify or reduce vulnerability. The framework is applied to New Zealand's tourism industry to explore its value in interpreting a complex, human-natural environment system with multiple competing vulnerabilities. The comprehensive contextual framework can inform government policy and industry decision making, integrating understandings of climate change within the broader context of internal and external social, physical, economic, and institutional stressors. PMID:24805920

  18. Savannah River Site management response plan for chemical safety vulnerability field assessment. Revision 1

    SciTech Connect

    Kahal, E.J.; Murphy, S.L.; Salaymeh, S.R.

    1994-09-01

    As part of the U.S. Department of Energy`s (DOE) initiative to identify potential chemical safety vulnerabilities in the DOE complex, the Chemical Safety Vulnerability Core Working Group issued a field verification assessment report. While the report concluded that Savannah River Site (SRS) is moving in a positive direction, the report also identified five chemical safety vulnerabilities with broad programmatic impact that are not easily nor quickly remedied. The May 1994 SRS Management Response Plan addressed the five SRS vulnerabilities identified in the field assessment report. The SRS response plan listed observations supporting the vulnerabilities and any actions taken or planned toward resolution. Many of the observations were resolved by simple explanations, such as the existence of implementation plans for Safety Analysis Report updates. Recognizing that correcting individual observations does not suffice in remedying the vulnerabilities, a task team was assembled to address the broader programmatic issues and to recommend corrective actions.

  19. Is There a Universal Understanding of Vulnerability? Experiences with Russian and Romanian Trainees in Research Ethics

    PubMed Central

    Loue, Sana; Loff, Bebe

    2014-01-01

    Vulnerability of participants in research and the provision of special protections for vulnerable research participants are key concepts in research ethics. Despite international consensus requiring special protections for vulnerable research participants, both the concept of vulnerability and the nature and adequacy of strategies to reduce vulnerability remain vague and, consequently, are subject to varying interpretations. We report on observations of the challenges faced in understanding this key concept by 20 Russian and Romanian trainees participating in a one-year M.A. training program in research ethics from 2000 through 2011. We describe how trainees’ understanding of and appreciation for the need for special protections of vulnerable research participants was nurtured. This paper is part of a collection of papers analyzing the Fogarty International Center's International Research Ethics Education and Curriculum Development program. PMID:24384513

  20. Mapping the groundwater vulnerability for pollution at the pan African scale

    NASA Astrophysics Data System (ADS)

    Ouedraogo, Issoufou; Defourny, Pierre; Vanclooster, Marnik

    2015-04-01

    We mapped the pan-African intrinsic and specific vulnerability of groundwater systems towards pollution. We compiled the most recent continental scale information on soil, land use, geology, hydrogeology and climate in a Geographical Information System (GIS) at the resolution of 15kmx15km and the 1:60,000,000 scale and implemented an indicator vulnerability model based on the DRASTIC method. The intrinsic vulnerability map reveals that groundwater is highly vulnerable in Central, West and some areas of North Africa, where the watertable is very low. The intrinsic vulnerability is very low in the large sedimentary basins of the African deserts where groundwater situates in very deep aquifers. The specific vulnerability is obtained by overlaying the intrinsic vulnerability with current land use. The specific vulnerability is high in North, Central, and West Africa and strongly related to water table depths and development of agricultural activities. Subsequently, we performed a sensitivity analysis to evaluate the relative importance of each indicator parameter on groundwater vulnerability for pollution. The sensitivity analysis indicated that the removal of the vadose zone impact, the depth of the groundwater, the hydraulic conductivity and the net recharge causes a large variation in the vulnerability index. The pan African assessment of groundwater vulnerability presented in this paper is expected to be of particular value for water policy and for designing water resources management programmes. We expect, however, that this assessment can be strongly improved when pan African monitoring data on groundwater pollution will be integrated in the assessment methodology. Keywords: groundwater vulnerability, pan-Africa, DRASTIC method, Sensitivity analysis, GIS