Note: This page contains sample records for the topic post authorization safety from Science.gov.
While these samples are representative of the content of Science.gov,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of Science.gov
to obtain the most current and comprehensive results.
Last update: November 12, 2013.
1

Linkage Between Post-Closure Safety Case Review and the Authorization Process for Radioactive Waste Disposal Facilities  

SciTech Connect

The Environment Agency (the Agency) has responsibilities under the Radioactive Substances Act of 1993 for regulating the disposal and storage of radioactive wastes in England and Wales, including regulation of the disposal site for UK solid low-level waste (LLW) at Drigg in Cumbria, NW England. To help inform the next review of the Drigg disposal authorization, the Agency has required the operator, British Nuclear Fuels plc to submit a Post-Closure Safety Case which will assess the potential long-term impacts from the site. With the aim of using best practice to determine authorization conditions, the Agency contracted Galson Sciences, Ltd to undertake an international survey of authorization procedures for comparable facilities in other countries. This paper provides an overview of the findings from the international survey.

Streatfield, I. J.; Duerden, S. L.; Yearsley, R. A.; Bennett, D. G.

2003-02-27

2

CRITICALITY SAFETY POSTING GUIDELINES  

SciTech Connect

This document provides a set of guidelines in the preparation of criticality safety postings. Guidance is provided in word choice, word arrangement, common human factors considerations. and use of color to highlight limits, cautions, and permissives.

JENSEN, M.A.

2001-11-01

3

Training in Post-authorization Pharmacovigilance  

PubMed Central

Post-authorization pharmacovigilance refers to all the activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problems, from the time a product gets the authorization to be marketed in a territory. The ultimate objective of pharmacovigilance is patient safety. To ensure this, any responsible pharmaceutical company will readily vouch for the importance of all these activities, each requiring specific training for efficient and effective execution. Having a well planned job specific training curriculum can help the organization realize its goals and objectives by covering the gaps between current and desired job performance levels and existing competencies of its employees. Apart from this, trainings can help in problem solving, increasing productivity and prepare for and respond to future changes in the organization or job duties. As the pharmaceutical business continues to grow, increasing numbers of skilled people are required to manage resultant increase in pharmacovigilance activities to remain compliant. Thus, the need for training qualified resources to develop into highly skilled pharmacovigilance professionals is the need of the hour. Currently, the supply-demand situation for skilled manpower is highly skewed in favor of the demand, as this field is relatively new in India and elsewhere. It is interesting to note that not many resources, be it internet, literature or books, are available specifically addressing the need of the industry to guide them on training requirements to set up and maintain a competent pharmacovigilance department. This article aims to present a comprehensive perspective on the trainings required in the post authorization scenario pertaining to pharmacovigilance activities and suggest ways to manage these in an efficient way so as to be compliant with the global norms and best practices.

Ahuja, Vivek; Sharma, Varun

2010-01-01

4

Post-marketing Monitoring of Vaccine Safety  

Center for Biologics Evaluation and Research (CBER)

Text Version... Post-marketing Monitoring of Vaccine Safety Pediatric Advisory Committee Meeting May 8, 2012 ... Data Minin Page 15. CDC Vaccine Safety Datalink ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

5

[Post-authorization research, registries, and drug development].  

PubMed

In the last decade regulators, payers and health care providers tried to react to three major problems in drug development and drug use in clinical practice: the pharmaceutical R&D productivity crisis, the immaturity of benefit-risk profile for several newly approved drugs and the overall impact on economic sustainability of reimbursing new high cost drugs in their systems. The potentiality of create a continuum between the evidence requirements relevant for registration, for reimbursement and for post authorization research is clear. All different parties involved, like regulators, HTA agencies, scientific communities and manufacturers, are working to improve the knowledge profile of new drugs in order to anticipate the patient access to innovation, limiting or preventing the clinical and economical risks deriving from an incomplete safety and effectiveness profile. The Italian example of "New Drugs AIFA Registries", with or without the application of risk sharing schemes (cost sharing, pay for performance, etc.), introduced a new process and increased the sensitivity on this topic. However this might probably represents only a partial answer to the problem of how to set up the governance of coverage with evidence, drug utilization monitoring, comparative effectiveness research, outcome research programs and may be how to link them to access, pricing and reimbursement. The step change in post authorization research could be to "integrate" different sources and stakeholders in a wider and continuous approach, in a well designed and inclusive "second generation" HTA approach, where all resources (competencies, data, funding) will concur to increase the evidence profile and reduce the risks, and where any "evidence generation approach" is really compliant with the standard and rules of best research practices. PMID:23801233

Patarnello, Francesca; Recchia, Giuseppe

2013-06-01

6

The relative burden of haemophilia A and the impact of target joint development on health-related quality of life: results from the ADVATE Post-Authorization Safety Surveillance (PASS) study.  

PubMed

Studies with haemophilia A (HA) patients have shown burden in health-related quality of life (HRQOL) when compared with general population norms. In the current study, HA patients' SF-36v2 health survey scores were compared with general population norms and to patients with other chronic conditions. The impact of target joints (TJs) on HRQOL was also examined. The sample was a subset of HA patients enrolled in the Post-Authorization Safety Surveillance (PASS) programme: a prospective open-label study in which ADVATE [Antihaemophilic Factor (Recombinant), Plasma/Albumin-Free Method] was prescribed. A total of 205 patients who were ? 18 years old and had SF-36v2 baseline scores were selected for this study. To measure the burden of HA on HRQOL, manova analyses compared these SF-36v2 scores to age- and gender-matched general population US and EU norms and to patients from other chronic condition groups. manova and correlational analyses examined the relations among TJ, age and SF-36v2 scores. Comparisons with general population norms confirm that HA negatively impacts physical, but not mental, HRQOL. Comparison with other chronic conditions shows the physical burden of HA is greater than for chronic back pain but similar to diabetes and rheumatoid arthritis, while the mental burden of HA is less than for all three patient groups. The presence of TJs was negatively associated with physical HRQOL, although this association was much larger for older patients (45+ years) than for younger ones. Physical, but not mental, HRQOL is diminished in HA patients. Target joints are associated with lower physical HRQOL, although this effect is moderated by age. PMID:21332888

Klamroth, R; Pollmann, H; Hermans, C; Faradji, A; Yarlas, A S; Epstein, J D; Ewenstein, B M

2011-02-21

7

[Advertising and safety in skiing (author's transl)].  

PubMed

Pertinent accident statistics show that, opposed to the need for safety which ought to be expected, there is an insufficiently practiced safety consciousness. The objective probability of getting into danger rises with the increasing readiness to take risks. Advertising tries to influence the potential customer quantitatively and qualitatively in such a way that he believes that his secret desires will be fulfilled by the acquisition and use of certain products. The mechanism of character transference through paralogical conclusions required for this shows parallels to the logic schizophrenia. Both sponsors and ad-men can contribute decisively to safety in skiing if they dispense with the use of certain attributes in their advertisements. PMID:403434

Neff, G; Nöth, W

1977-02-11

8

Lack of Authority Hampers Attempts to Increase Cosmetic Safety.  

National Technical Information Service (NTIS)

The Congress should authorize the Food and Drug Administration to require cosmetic manufacturers to prove the safety of their products. Because the agency does not have enough authority to effectively regulate cosmetics, products are being marketed which ...

1978-01-01

9

76 FR 63988 - Pilot Project on NAFTA Trucking Provisions; Pre-Authorization Safety Audits  

Federal Register 2010, 2011, 2012, 2013

...Project on NAFTA Trucking Provisions; Pre-Authorization Safety Audits AGENCY: Federal Motor Carrier Safety Administration (FMCSA...data and information concerning the Pre-Authorization Safety Audits (PASAs) for two motor carriers that applied to...

2011-10-14

10

Meanctra: Post-licensure Pediatric Safety and Adverse Event ...  

Center for Biologics Evaluation and Research (CBER)

Text Version... Post-licensure Pediatric Safety and Adverse Event Review Pediatric Advisory Committee Meeting ... 9 Page 10. Adverse Events Reported to VAERS ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

11

78 FR 28897 - Tennessee Valley Authority; Establishment of Atomic Safety and Licensing Board  

Federal Register 2010, 2011, 2012, 2013

...Tennessee Valley Authority; Establishment of Atomic Safety and Licensing Board Pursuant to...321, notice is hereby given that an Atomic Safety and Licensing Board (Board) is...judges: Alex S. Karlin, Chairman, Atomic Safety and Licensing Board Panel,...

2013-05-16

12

23 CFR 1200.4 - State Highway Safety Agency-Authority and functions.  

Code of Federal Regulations, 2013 CFR

...2013-04-01 false State Highway Safety Agency-Authority and functions. 1200... Highways NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION AND FEDERAL HIGHWAY ADMINISTRATION...TRANSPORTATION PROCEDURES FOR STATE HIGHWAY SAFETY PROGRAMS UNIFORM PROCEDURES FOR...

2013-04-01

13

Post-Approval Drug Safety Surveillance  

PubMed Central

Following the drug-approval process, concerns remain regarding the safety of new drugs that are introduced into the marketplace. In the case of rare adverse events, the number of subjects that are treated in randomized controlled trials is invariably inadequate to determine the safety of the new pharmaceutical. Identifying safety signals for new and/or existing drugs is a major priority in the protection of public health. Unfortunately, design, analysis, and available data are often quite limited for detecting in a timely fashion any potentially harmful effects of drugs. In this review, we examine a variety of approaches for determining the possibility of adverse drug reactions. Our review includes spontaneous reports, meta-analysis of randomized controlled clinical trials, ecological studies, and analysis of medical claims data. We consider both experimental design and analytic problems as well as potential solutions. Many of these methodologies are then illustrated through application to data on the possible relationship between taking antidepressants and increased risk of suicidality.

Amatya, Anup K.; Hur, Kwan; Marcus, Sue M.; Bhaumik, Dulal K.; Mann, J. John

2009-01-01

14

Methods for observational post-licensure medical product safety surveillance.  

PubMed

Post-licensure medical product safety surveillance is important for detecting adverse events potentially not identified pre-licensure. Historically, post-licensure safety monitoring has been accomplished using passive reporting systems and by conducting formal Phase IV randomized trials or large epidemiological studies, also known as safety surveillance or pharmacovigilance studies. However, crucial gaps in the safety evidence base provided by these approaches have led to high profile product withdrawals and growing public concern about unknown health risks associated with licensed products. To address the limitations of existing surveillance systems and to facilitate more accurate and rapid detection of safety problems, new systems involving active surveillance of large, population-based cohorts using observational health care utilization databases are being developed. In this article, we review common statistical methods that have been employed previously for post-licensure safety monitoring, including data mining and sequential hypothesis testing, and assess which methods may be promising for potential use within this newly proposed prospective observational cohort monitoring framework. We discuss gaps in existing approaches and identify areas where methodological development is needed to improve the success of safety surveillance efforts in this setting. PMID:22138688

Nelson, Jennifer C; Cook, Andrea J; Yu, Onchee; Zhao, Shanshan; Jackson, Lisa A; Psaty, Bruce M

2011-12-01

15

30 CFR 75.363 - Hazardous conditions and violations of mandatory health or safety standards; posting, correcting...  

Code of Federal Regulations, 2013 CFR

...conditions and violations of mandatory health or safety standards; posting, correcting... Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY...

2013-07-01

16

Safety Signals Using Proportional Reporting Ratios from Company and Regulatory Authority Databases  

Microsoft Academic Search

Databases held by regulatory agencies and by pharmaceutical companies may be used to detect safety signals. We compared the utility of a company safety database with those from two large regulatory authority databases in assessing potential safety signals in order to understand how the different sources may be used. Proportional reporting ratios (PRRs) were calculated from the company database for

Andrzej Czarnecki; Simon Voss

2008-01-01

17

Assessment of consumer food safety education provided by local authorities in the UK  

Microsoft Academic Search

Purpose – The purpose of this paper is to examine the extent, sources, diversity, costs, formats and content of food safety educational interventions for consumers provided by UK Local Authorities (LAs). Inadequate implementation of food safety practices in the home is known to contribute to the incidence of foodborne disease and therefore effective food safety education concerning risks and correct

Elizabeth C. Redmond; Christopher J. Griffith

2006-01-01

18

Student-observed surgical safety practices across an urban regional health authority  

Microsoft Academic Search

Background and aimRecognising the global push for patient safety in healthcare, students in medicine and nursing participated in a project to compare surgical safety practices in the Winnipeg Regional Health Authority (WRHA) with the WHO surgical safety checklist.MethodologyStudents volunteered to participate and were oriented to operating room (OR) protocol and the WHO surgical safety checklist. Over a 1-month period, 130

Jessica Spence; Barb Goodwin; Carol Enns; Heather Dean

2011-01-01

19

[Post traumatic schizophrenic bouts: with regard to 6 cases of traumatic schizophrenia (author's transl)].  

PubMed

The authors describe 6 cases of post-traumatic schizophrenia and make a critical review of the literature concerning this unusual post-traumatic personality disturbance. Various schizophrenic manifestations are observed: they principally consist of delusion, hallucination, paranoid and mystical ideas, autism, psychomotor instability, fugues. Post-traumatic schizophrenia occurs mostly in young men, before thirty years. The severity of traumatic brain injury appears irrelevant in its genesis. Temporal lobes are more often involved (one third of the cases). Pre-traumatic personality disturbances are the main factor as demonstrated by the anamnesis and by the results of Rorschach test. PMID:7094869

De Mol, J; Violon, A; Brihaye, J

1982-01-01

20

Post-earthquake building safety assessments for the Canterbury Earthquakes  

USGS Publications Warehouse

This paper explores the post-earthquake building assessment program that was utilized in Christchurch, New Zealand following the Canterbury Sequence of earthquakes beginning with the Magnitude (Mw.) 7.1 Darfield event in September 2010. The aftershocks or triggered events, two of which exceeded Mw 6.0, continued with events in February and June 2011 causing the greatest amount of damage. More than 70,000 building safety assessments were completed following the February event. The timeline and assessment procedures will be discussed including the use of rapid response teams, selection of indicator buildings to monitor damage following aftershocks, risk assessments for demolition of red-tagged buildings, the use of task forces to address management of the heavily damaged downtown area and the process of demolition. Through the post-event safety assessment program that occurred throughout the Canterbury Sequence of earthquakes, many important lessons can be learned that will benefit future response to natural hazards that have potential to damage structures.

Marshall, J.; Barnes, J.; Gould, N.; Jaiswal, K.; Lizundia, B.; Swanson, D.; Turner, F.

2012-01-01

21

Regulations concerning the organisation and functions of the Nuclear Safety Authority.  

National Technical Information Service (NTIS)

The Regulations lay down the Nuclear Safety Authority's responsibilities under the 1972 Act on Nuclear Energy Activities and provide for its composition and work organisation. (Atomindex citation 23:009179)

1973-01-01

22

Authoring.  

ERIC Educational Resources Information Center

|Describes how the integration of sound and images in multimedia presentations may affect the future of writing. Discusses the impact on the concepts of "author" and "authorship." Focuses on the importance of knowing how integrated media texts work. Posits that children already perceive the relationship between image, word, and sound as being…

Moore, Phil

1994-01-01

23

Reevaluating nuclear safety and security in a post 9/11 era.  

SciTech Connect

This report has the following topics: (1) Changing perspectives on nuclear safety and security; (2) Evolving needs in a post-9/11 era; (3) Nuclear Weapons--An attractive terrorist target; (4) The case for increased safety; (5) Evolution of current nuclear weapons safety and security; (6) Integrated surety; (7) The role of safety and security in enabling responsiveness; (8) Advances in surety technologies; and (9) Reevaluating safety.

Booker, Paul M.; Brown, Lisa M.

2005-07-01

24

Scientific Method and the Regulation of Health and Nutritional Claims by the European Food Safety Authority  

Microsoft Academic Search

The protection of European consumers from the false or misleading scientific and nutritional claims of food manufacturers took a step forward with the recent opinions of the European Food Safety Authority (EFSA). As a risk assessment agency, the EFSA recently assessed and rejected a vast number of food claim forcing the withdrawal of many claims from leading manufacturers. Focusing on

Darren Hoad

2011-01-01

25

The fifth anniversary of the European Food Safety Authority (EFSA): Mission, organization, functioning and main results  

Microsoft Academic Search

The European Food Safety Authority (EFSA), founded by Regulation EC 178\\/2002, is now in its fifth year of activity and has already gone through a positive external evaluation procedure. This paper takes the reader through the many objectives of this Organization in defining the mission of EFSA as well as the organizational structure that has been developed so far in

Marco Silano; Vittorio Silano

2008-01-01

26

Scientific Method and the Regulation of Health and Nutritional Claims by the European Food Safety Authority  

ERIC Educational Resources Information Center

|The protection of European consumers from the false or misleading scientific and nutritional claims of food manufacturers took a step forward with the recent opinions of the European Food Safety Authority (EFSA). As a risk assessment agency, the EFSA recently assessed and rejected a vast number of food claim forcing the withdrawal of many claims…

Hoad, Darren

2011-01-01

27

British Muslims and community safety post- September 11th  

Microsoft Academic Search

This article examines the community safety issues facing British Muslims. The events of September 11th have had a particular impact upon Muslims' experiences of crime, criminal justice and their feelings of (un)safety. As such, agencies working in the criminal justice and community safety sectors must take into consideration British Muslim identities and the specific needs of Muslim communities.

Basia Spalek

2005-01-01

28

Request for post-marketing safety data for Cervarix, October 2 ...  

Center for Biologics Evaluation and Research (CBER)

... Approval History, Letters, Reviews, and Related Documents - Cervarix. -. Request for post-marketing safety data for Cervarix, October 2, 2007. ... More results from www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts

29

Maritime Safety in the Post-Prestige Era  

Microsoft Academic Search

The Prestige accident is perhaps the last among a series of serious marine accidents that have significantly shaped the formulation of maritime safety policy worldwide. The main thesis of this paper is that in spite of recent progress in this area there is still a long way to achieve a truly 'proactive' maritime safety regime. A qualitative assessment on the

Harilaos N. Psaraftis

30

Transition temperature considerations when extrapolating safety-related equipment post-accident operating times  

Microsoft Academic Search

Qualified life is the period of operational aging time prior to an accident event (assumed to be a postulated high energy pipe break) that an item of safety-related equipment is assured by test and analysis to remain capable of performing its post-accident safety function. Qualified post-accident operating time is the amount of time after an accident begins that an item

Greg M. Hostetter; David A. Horvath

2003-01-01

31

Transition temperature considerations when extrapolating safety-related equipment post-accident operating times  

Microsoft Academic Search

Qualified life is the amount of aging time prior to an accident that an item of safety-related equipment is assured by test and analysis to still be capable of performing its safety function even when exposed to the harsh environment of that accident (assumed to be a postulated high energy pipe break). Qualified post-accident operating time is the amount of

Greg M. Hostetter; David A. Horvath

2004-01-01

32

Review of CBER's Current and Planned Post-marketing Safety ...  

Center for Biologics Evaluation and Research (CBER)

Text Version... Review adverse event reports, pharmacovigilance plans, study protocols ... Overall plan is to ... review of CBER's current and planned post-marketing ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

33

[Necessity of applying pharmacovigilance in post-marketing safety monitoring of traditional Chinese medicine injections].  

PubMed

Traditional Chinese medicine (TCM) injection has become one of the hotspots in the new TCM research and development. The serious adverse drug reactions happened in clinical have arosed attention widely in the whole society. It's very urgent to monitor the post-marketing safety of TCM injections. This paper elucidated the pharmacovigilance's necessity in the post-marketing safety monitoring of TCM injections, basing on the reason of safety problem of TCM injections and the future developing trend of adverse drug reaction monitoring. Also, this paper introduced the rapid signal detection method of spontaneous reporting system database by data mining technology. PMID:18536393

Wang, Hai-Nan; Chen, Wen; Fu, Zheng; Du, Wen-min; He, Jia

2008-03-01

34

10 CFR 35.57 - Training for experienced Radiation Safety Officer, teletherapy or medical physicist, authorized...  

Code of Federal Regulations, 2013 CFR

...2013-01-01 false Training for experienced Radiation Safety Officer, teletherapy or medical... § 35.57 Training for experienced Radiation Safety Officer, teletherapy or medical...1) An individual identified as a Radiation Safety Officer, a teletherapy...

2013-01-01

35

Qualified presumption of safety (QPS): a generic risk assessment approach for biological agents notified to the European Food Safety Authority (EFSA)  

Microsoft Academic Search

Qualified Presumption of Safety (QPS) is a generic risk assessment approach applied by the European Food Safety Authority (EFSA) to notified biological agents aiming at simplifying risk assessments across different scientific Panels and Units. The aim of this review is to outline the implementation and value of the QPS assessment for EFSA and to explain its principles such as the

Renata G. K. Leuschner; Tobin P. Robinson; Marta Hugas; Pier Sandro Cocconcelli; Florence Richard-Forget; Günter Klein; Tine R. Licht; Christophe Nguyen-The; Amparo Querol; Malcolm Richardson; Juan E. Suarez; Ulf Thrane; Just M. Vlak; Atte von Wright

2010-01-01

36

Safe Physical Activity Environments--To What Extent Are Local Government Authorities Auditing the Safety of Grassed Sporting Grounds?  

ERIC Educational Resources Information Center

Physical activity (PA) participation is influenced by the safety of the settings in which it is undertaken. This study describes the grounds assessment practices of Local Government Authorities (LGAs) in Victoria, Australia to ensure the safety of grassed sporting grounds. It also makes recommendations for improving these practices to maximise the…

Otago, Leonie; Swan, Peter; Donaldson, Alex; Payne, Warren; Finch, Caroline

2009-01-01

37

41 CFR 302-9.209 - Under what conditions may my agency authorize me to transport from my post of duty a replacement...  

Code of Federal Regulations, 2012 CFR

...false Under what conditions may my agency authorize me to transport from my post of duty a replacement POV purchased at that post...209 Under what conditions may my agency authorize me to transport from my post of duty a replacement POV purchased at that...

2012-07-01

38

41 CFR 302-9.209 - Under what conditions may my agency authorize me to transport from my post of duty a replacement...  

Code of Federal Regulations, 2011 CFR

...false Under what conditions may my agency authorize me to transport from my post of duty a replacement POV purchased at that post...209 Under what conditions may my agency authorize me to transport from my post of duty a replacement POV purchased at that...

2011-07-01

39

Private authority and disaster relief: The cases of post-tsunami Aceh and Nias  

Microsoft Academic Search

This article explores the rise of private authority in globalized disaster relief scenarios by looking at the case of nongovernmental organizations (NGOs) operating in Aceh and its neighboring region, Nias, after the December 2004 Indian Ocean tsunami. The author places the growing strength and presence of NGOs within the larger context of weak, cash-strapped local governments under decentralization schemes promoted

Chhandasi Pandya

2006-01-01

40

77 FR 71454 - Notice of Atomic Safety And Licensing Board Reconstitution, Tennessee Valley Authority (Watts Bar...  

Federal Register 2010, 2011, 2012, 2013

...09-893-01-OL-BD01] Notice of Atomic Safety And Licensing Board Reconstitution...2.313(c) and 2.321(b), the Atomic Safety and Licensing Board (Board) in...Hawkens, Chief Administrative Judge, Atomic Safety and Licensing Board Panel....

2012-11-30

41

Why the European Food Safety Authority was right to reject health claims for probiotics.  

PubMed

Probiotics are microbes that are claimed to promote health and well-being when added to foods. However, the European Food Safety Authority (EFSA) has so far advised negatively about health claims for probiotics. Companies and scientists have protested against these rejections, sometimes in vigorous language. I argue that EFSA could not have acted differently, given EU regulations and the lack of convincing evidence for some of the claimed effects of probiotics on human health and well-being. One EU regulation that makes it hard to demonstrate the benefits of probiotics is the prohibition of medical claims, i.e. claims that a food prevents or cures a disease. If this prohibition did not exist, manufacturers of nutritional treatments might circumvent the costly procedures required for drugs, and market their products to ill people without thorough proof that they are effective and safe. However, the prohibition is also a legal fiction, because promotion of health and prevention of disease is largely the same thing. EFSA has recently indicated that it will allow health claims based on the ability of probiotics to reduce infections. To a certain extent, this abolishes the distinction between health claims and medical claims. It remains to be seen if probiotics producers can convince EFSA that their products prevent or cure infections and other diseases in humans. PMID:22683835

Katan, M B

2012-06-01

42

Back to the Future: Leadership, Tradition, and Authority in a Post-Critical Age  

ERIC Educational Resources Information Center

|Both modern and postmodern approaches to knowledge view tradition and authority with suspicion, even contempt, though each approach does so in different ways. Our profession vacillates between those epistemological orientations, struggling to find direction and meaning. Leadership, in particular, is in a quandary; what does leadership look like…

Hawkins, Andrew

2010-01-01

43

10 CFR 35.57 - Training for experienced Radiation Safety Officer, teletherapy or medical physicist, authorized...  

Code of Federal Regulations, 2010 CFR

...medical physicist, authorized user, nuclear pharmacist, and authorized nuclear pharmacist. 35.57 Section 35.57 Energy NUCLEAR...medical physicist, authorized user, nuclear pharmacist, and authorized nuclear pharmacist....

2010-01-01

44

10 CFR 35.57 - Training for experienced Radiation Safety Officer, teletherapy or medical physicist, authorized...  

Code of Federal Regulations, 2010 CFR

...medical physicist, authorized user, nuclear pharmacist, and authorized nuclear pharmacist. 35.57 Section 35.57 Energy NUCLEAR...medical physicist, authorized user, nuclear pharmacist, and authorized nuclear pharmacist....

2009-01-01

45

Motor Vehicle Safety Authorization Act of 1986. House of Representatives, Ninety-Ninth Congress, Second Session, September 17, 1986  

SciTech Connect

The House Committee on Energy and Commerce suggests several amendments to H.R. 2248, which authorizes National Highway Traffic Safety Administration appropriations for 1987-1988. The legislation addresses such safety issues as the requirement that dealers inform potential buyers of true odometer readings, tire registration, bumper strength, and defects. The report covers automobile recalls of the past decade, the need for safety standard equality certification for imports, and state safety inspection programs. Oversight hearings and findings of the committee also addressed mandatory seat belt use. The bill affects the National Traffic and Motor Vehicle Safety Act of 1966 and the Motor Vehicle Information and Cost Savings Act. The report notes several areas of compromise.

Not Available

1986-01-01

46

Structural safety assessment under the low temperature of KSTAR superconducting magnet-supporting post  

NASA Astrophysics Data System (ADS)

A magnet-supporting post installed between the lower TF coil cooled by 4.5 K supercritical helium and the cryostat base is one of the most important components of the superconducting magnet-supporting structure for KSTAR Tokamak. This structure should be flexible to absorb thermal shrink of the magnet and should also be rigid to support the magnet weight and the plasma disruption load. The post was designed with stainless steel (SS) 316 LN and carbon fiber reinforced plastic (CFRP) that has low thermal conductivity and high structural strength at low temperature. In order to verify the fabricability and the structural safety, a whole scale prototype of the KSTAR magnet-supporting post was manufactured and tested. Both static and compressive cyclic load tests under the maximum plasma vertical disruption load and the magnet dead weight were performed. The test results showed that the magnet-supporting post of KSTAR Tokamak was fabricable and structurally rigid.

Her, N. I.; Sa, J. W.; Cho, S.; Do, C. J.; Choi, C. H.; Kim, B. C.; Im, K. H.; Kyum, M.; Kim, W. C.; Kim, G. H.; Yoo, B. J.; Oh, Y. K.; Kim, D. L.; Kwon, M.; Lee, G. S.; Kstar Team

2001-01-01

47

The Food and Drug Administration's Post-Licensure Rapid Immunization Safety Monitoring program: strengthening the federal vaccine safety enterprise.  

PubMed

In 2009, the Department of Health and Human Services created the new Post-Licensure Rapid Immunization Safety Monitoring (PRISM) program, which used data from national health insurance plans and immunization registries to monitor the safety of the H1N1 influenza vaccine. PRISM has now been integrated into the FDA's Mini-Sentinel pilot program. It strengthens the federal vaccine safety enterprise in two important ways. First, PRISM monitors the largest US general population cohort designated for active surveillance of vaccine safety. Second, PRISM links data from health plans with data from state and city immunization registries, which were a crucial source of exposure data in the H1N1 vaccine evaluation. The Mini-Sentinel data that support PRISM are updated quarterly, and PRISM can conduct medical record review for validation of computerized data. The FDA has structured PRISM as a program that includes specific vaccine evaluations, development of an operational framework to guide the design of vaccine safety evaluations, and development of new statistical methods. A human papillomavirus vaccine, Gardasil, and two rotavirus vaccines, RotaTeq and Rotarix, have been chosen for surveillance in the current cycle because their evaluations would benefit most from PRISM's large cohort size. The PRISM program creates important opportunities by offering a robust, responsive new surveillance program with features complementary to existing systems. Methodological and logistical lessons can be shared among PRISM and other surveillance systems, offering potential synergies. FDA and PRISM will work to maximize the program's unique strengths and contributions to a unified federal vaccine safety enterprise. PMID:22262619

Nguyen, Michael; Ball, Robert; Midthun, Karen; Lieu, Tracy A

2012-01-01

48

41 CFR 302-9.203 - Is there any circumstance under which I may be authorized to transport my POV from a post of duty...  

Code of Federal Regulations, 2011 CFR

...Is there any circumstance under which I may be authorized to transport my POV from a post of duty before completing my service agreement...Is there any circumstance under which I may be authorized to transport my POV from a post of duty before completing my service...

2011-07-01

49

41 CFR 302-9.203 - Is there any circumstance under which I may be authorized to transport my POV from a post of duty...  

Code of Federal Regulations, 2012 CFR

...Is there any circumstance under which I may be authorized to transport my POV from a post of duty before completing my service agreement...Is there any circumstance under which I may be authorized to transport my POV from a post of duty before completing my service...

2012-07-01

50

49 CFR Appendix A to Subpart E of... - Explanation of Pre-Authorization Safety Audit Evaluation Criteria for Mexico-Domiciled Motor...  

Code of Federal Regulations, 2010 CFR

...Pre-Authorization Safety Audit Evaluation Criteria for Mexico-Domiciled Motor Carriers A Appendix...AUTHORITY Special Rules for Certain Mexico-domiciled Carriers Pt. 365, Subpt...Pre-Authorization Safety Audit Evaluation Criteria for Mexico-Domiciled Motor Carriers I....

2009-10-01

51

49 CFR Appendix A to Subpart E of... - Explanation of Pre-Authorization Safety Audit Evaluation Criteria for Mexico-Domiciled Motor...  

Code of Federal Regulations, 2010 CFR

...Pre-Authorization Safety Audit Evaluation Criteria for Mexico-Domiciled Motor Carriers A Appendix...AUTHORITY Special Rules for Certain Mexico-domiciled Carriers Pt. 365, Subpt...Pre-Authorization Safety Audit Evaluation Criteria for Mexico-Domiciled Motor Carriers I....

2010-10-01

52

Post-marketing surveillance study of the safety and efficacy of sildenafil prescribed in primary care to erectile dysfunction patients  

Microsoft Academic Search

In order to investigate the safety and efficacy of sildenafil prescribed in primary care, a post-marketing surveillance study was undertaken. A total of 651 men with erectile dysfunction (ED) were enrolled from 31 family physicians in Korea from December 1999 to July 2002. Patients were regularly followed up to ascertain the safety and efficacy of sildenafil. Of the 651 patients

S Sunwoo; Y S Kim; B L Cho; K S Cheon; H G Seo; M K Rho; Y S Cheong; M H Hong; S W Kim; D H Kim

2005-01-01

53

The safety of post-exposure vaccination of mice infected with Mycobacterium tuberculosis.  

PubMed

New post-exposure tuberculosis vaccination strategies are being developed to prevent disease in individuals latently infected with Mycobacterium tuberculosis. However, concerns about the potential induction of deleterious Koch-like reactions after immunization of persons with latent tuberculosis has limited progress in assessing the effectiveness of post-exposure vaccination. To evaluate the safety of immunization after M. tuberculosis infection, two mouse models were established, a drug treatment low bacterial burden model and an active disease model. Twelve different M. tuberculosis antigen preparations and vaccines (including DNA, subunit, viral vectored, and live, attenuated vaccines) were evaluated using these mouse models. In the low bacterial burden model, post-exposure vaccination did not induce significant reactivational disease and only injection of BCG evoked increases in lung inflammatory responses at 1 month after the immunizations. Additionally, although significant increases in lung inflammation were seen for animals injected with the hps65 DNA vaccine or a M. tuberculosis culture supernatant preparation, no differences in the survival periods were detected between vaccinated and non-vaccinated mice at 10 months post-immunization using the low bacterial burden model. For the active disease model, significantly more lung inflammation was observed at 1 month after administration of the hsp65 DNA vaccine but none of the antigen preparations tested increased the lung bacterial burdens at this early time point. Furthermore, vaccination of diseased mice with BCG or TB DNA vaccines did not significantly affect mortality rates compared to non-vaccinated controls at 10 months post-immunization. Overall, these data suggest that while the potential risk of inducing Koch-like reactions is low after immunization of persons with latent tuberculosis, extreme caution is still needed as post-exposure vaccines progress from pre-clinical experiments into the initial phases of clinical testing. PMID:18809446

Derrick, Steven C; Perera, L P; Dheenadhayalan, Veerabadran; Yang, Amy; Kolibab, Kristopher; Morris, Sheldon L

2008-09-20

54

41 CFR 302-9.172 - Under what conditions may my agency authorize transportation of a replacement POV to my post of...  

Code of Federal Regulations, 2011 CFR

...conditions may my agency authorize transportation of a replacement POV to my post of...System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 9-ALLOWANCES FOR TRANSPORTATION AND EMERGENCY STORAGE OF A...

2011-07-01

55

41 CFR 302-9.140 - Under what specific conditions may my agency authorize transportation of a POV to my post of duty...  

Code of Federal Regulations, 2011 CFR

...conditions may my agency authorize transportation of a POV to my post of duty upon...System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 9-ALLOWANCES FOR TRANSPORTATION AND EMERGENCY STORAGE OF A...

2011-07-01

56

41 CFR 302-9.170 - Under what specific conditions may my agency authorize transportation of a POV to my post of duty...  

Code of Federal Regulations, 2012 CFR

...conditions may my agency authorize transportation of a POV to my post of duty subsequent...System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 9-ALLOWANCES FOR TRANSPORTATION AND EMERGENCY OR TEMPORARY...

2012-07-01

57

41 CFR 302-9.172 - Under what conditions may my agency authorize transportation of a replacement POV to my post of...  

Code of Federal Regulations, 2012 CFR

...conditions may my agency authorize transportation of a replacement POV to my post of...System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 9-ALLOWANCES FOR TRANSPORTATION AND EMERGENCY OR TEMPORARY...

2012-07-01

58

41 CFR 302-9.140 - Under what specific conditions may my agency authorize transportation of a POV to my post of duty...  

Code of Federal Regulations, 2012 CFR

...conditions may my agency authorize transportation of a POV to my post of duty upon...System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 9-ALLOWANCES FOR TRANSPORTATION AND EMERGENCY OR TEMPORARY...

2012-07-01

59

PAT-1 safety analysis report addendum author responses to request for additional information.  

SciTech Connect

The Plutonium Air Transportable Package, Model PAT-1, is certified under Title 10, Code of Federal Regulations Part 71 by the U.S. Nuclear Regulatory Commission (NRC) per Certificate of Compliance (CoC) USA/0361B(U)F-96 (currently Revision 9). The National Nuclear Security Administration (NNSA) submitted SAND Report SAND2009-5822 to NRC that documented the incorporation of plutonium (Pu) metal as a new payload for the PAT-1 package. NRC responded with a Request for Additional Information (RAI), identifying information needed in connection with its review of the application. The purpose of this SAND report is to provide the authors responses to each RAI. SAND Report SAND2010-6106 containing the proposed changes to the Addendum is provided separately.

Weiner, Ruth F.; Schmale, David T.; Kalan, Robert J.; Akin, Lili A.; Miller, David Russell; Knorovsky, Gerald Albert; Yoshimura, Richard Hiroyuki; Lopez, Carlos; Harding, David Cameron; Jones, Perry L.; Morrow, Charles W.

2010-09-01

60

Assessing the safety of post-exposure rabies immunization in pregnancy.  

PubMed

Fourteen pregnant women who received rabies post-exposure prophylaxis (PEP) at the anti-rabies clinic (ARC) of Kempegowda Institute of Medical Sciences (KIMS) were followed up for assessing the safety of modern rabies vaccines and equine rabies immunoglobulin (ERIG) in pregnancy. The women were in the age range of 18-28 years, mostly from urban area (64%) and exposed to suspect rabid dogs (86%). They had received purified vero cell rabies vaccine (Verorab = 8 and Abhayrab = 4), purified chick embryo cell vaccine (Rabipur = 2) by Essen regimen; and equine rabies immunoglobulin (Equirab = 7 and Pasteur anti-rabies serum = 1). None of the pregnant women reported any adverse events to either vaccine or equine rabies immunoglobulin. All had safe vaginal deliveries and in all cases both the mother and the child were found to be healthy and normal. PMID:17375003

Sudarshan, M K; Giri, M S Ananda; Mahendra, B J; Venkatesh, G M; Sanjay, T V; Narayana, D H Ashwath; Ravish, H S

2007-05-06

61

Index to Nuclear Safety. A technical progress review by chronology, permuted title, and author. Vol 11, No. 1 through Vol. 16, No. 6  

SciTech Connect

This index to Nuclear Safety covers articles in Nuclear Safety Vol. 11, No. 1 (Jan.-Feb. 1970) through Vol. 16, No. 6 (Nov.-Dec. 1975). Included in the index is a chronological list of articles (including abstract) followed by both a KWIC index and an Author Index. Nuclear Safety is a bimonthly technical progress review prepared by the Nuclear Safety Information Center and covers all safety aspects of nuclear power reactors and associated facilities. The index lists over 300 technical articles in the last six years of publication.

Cottrell, W.B.; Klein, A.

1976-04-01

62

Efficacy and Safety of the Angioseal Vascular Closure Device Post Antegrade Puncture  

SciTech Connect

In this study, the efficacy and safety of the Angioseal vascular closure device post antegrade puncture of the common femoral artery (CFA) for lower limb vascular interventional procedures are evaluated. A retrospective analysis of the medical records of 60 consecutive patients who were referred for interventional procedures in the superficial femoral artery (SFA) or popliteal artery (popl. art.) was performed. Antegrade puncture was successfully performed in 58 of 60 patients (96.6%). Indications included right SFA angioplasty (n = 35), left SFA angioplasty (n = 17), right popl. art. angioplasty (n = 5), and left popl. art. angioplasty (n = 1). Hemostasis was achieved by, on an intention-to-treat basis, the Angioseal vascular closure device in 46 patients and manual compression in 12 patients. Manual compression was used instead of Angioseal because of severe calcified arterial wall plaques (n = 7), failed deployment of the Angioseal (n = 4), and left SFA dissection (n = 1). There were no major recorded complications in the Angioseal group despite the use of antiplatelet or anticoagulant medications. Twenty-three (50%) of the patients in the Angioseal group were discharged within 24 h. Thirty-seven of the 46 patients who received an Angioseal device had undergone a previous ipsilateral CFA puncture (time range, 2 days to 56 months; mean, 6.2 months). Nine of these patients had undergone ipsilateral Angioseal deployment in the previous 3 months. We conclude that the Angioseal vascular closure device is a safe and efficient means of achieving hemostasis post antegrade puncture.

Looby, S.; Keeling, A. N.; McErlean, A.; Given, M. F.; Geoghegan, T.; Lee, M. J. [Beaumont Hospital, Department of Radiology (Ireland)], E-mail: mlee@rcsi.ie

2008-05-15

63

Safety of the long-acting neuraminidase inhibitor laninamivir octanoate hydrate in post-marketing surveillance.  

PubMed

Laninamivir octanoate hydrate (laninamivir) is a long-acting neuraminidase inhibitor (NAI) that completes treatment with only a single inhalation. It was launched in Japan in October 2010 as an anti-influenza agent. A post-marketing surveillance study was conducted in the 2010/2011 influenza season to assess the safety of this drug in clinical settings. Adverse drug reactions (ADRs) were observed in 50 patients (59 events) out of 3542 patients subjected to safety evaluation (incidence 1.41%). Commonly reported ADRs were psychiatric disorders (abnormal behaviour, etc.), gastrointestinal disorders (diarrhoea, nausea, etc.) and nervous system disorders (dizziness, etc.), with incidences of 0.48% (n=17), 0.45% (n=16) and 0.17% (n=6), respectively. No serious ADRs occurred. ADRs usually emerged on the day on which laninamivir was inhaled (52.5%) and ADRs emerged within 3 days after inhalation in >90% of adversely affected patients. ADRs resolved or improved within 3 days in >85% of patients. The incidence of adverse events involving abnormal behaviour was 3.1% (30/959) among patients <10 years of age, 0.7% (8/1088) among patients aged 10-19 years, 0.1% (2/1431) among adult patients aged 20-64 years and 0.0% (0/64) among patients aged ?65 years. It was confirmed that laninamivir is unlikely to cause delayed ADRs or a prolonged duration of ADRs despite this drug being a long-acting NAI. Furthermore, the incidence of ADRs was not found to have increased compared with that observed during clinical trials, and the types of ADR observed during this study were similar to those previously observed. Thus, laninamivir octanoate hydrate was confirmed to have no noticeable problem with safety. PMID:22871369

Kashiwagi, Seizaburo; Yoshida, Sanae; Yamaguchi, Hiroki; Niwa, Shinpei; Mitsui, Noriko; Tanigawa, Masatoshi; Shiosakai, Kazuhito; Yamanouchi, Naoki; Shiozawa, Tomoo; Yamaguchi, Fumie

2012-08-04

64

Technical challenges in designing post-marketing eCRFs to address clinical safety and pharmacovigilance needs.  

PubMed

To identify key challenges and propose technical considerations in designing electronic case report form (eCRF) for post-marketing studies, the author undertakes a comprehensive literature review of peer reviewed and grey literature to assess the key aspects, processes, standards, recommendations, and best practices in designing eCRFs based on industry experience in designing and supporting electronic data capture (EDC) studies. Literature search using strings on MEDLINE and PUBMED returned few papers directly related to CRF design. Health informatics and general practice journals were searched and results reviewed. Many conference, government commission, health professional and special interests group websites provide relevant information from practical experience - summarization of this information is presented. Further, we presented a list of concrete technical considerations in dealing with EDC technology/system limitations based on literature assessment and industry implementation experience. It is recognized that cross-functional teams be involved in eCRF design process and decision making. To summarize the keys in designing eCRFs to address post-market study safety and pharmacovigilance needs, the first is to identify required data elements from the study protocol supporting data analyses and reporting requirements. Secondly, accepted best practices, CDASH & CDISC guidelines, and company internal or therapeutic unit standard should be considered and applied. Coding (MedDRA & WHODD) mapping should be managed and implemented as well when possible. Finally, we need to be on top of the EDC technologies, challenge the technologies, drive EDC improvement via working with vendors, and utilize the technologies to drive clinical effectiveness. PMID:19900576

Lu, Zhengwu

2009-11-10

65

[Studies on pre- and post-natal malnutrition in albino rats. Partial ponderal and biochemic recuperation (author's transl)].  

PubMed

Attempts at restoring the state of malnutrition experimentally induced in rats during pre- and post-natal periods, led to the following remarks: 1) animals fed a normal diet soon improved their weight and levels of this blood proteins; 2) the restoration levels obtained at the end of 120 days of treatment did not reach, however, that obtained by the control animals. PMID:814588

Campos, D G; Madi, K

66

30 CFR 774.11 - Post-permit issuance requirements for regulatory authorities and other actions based on ownership...  

Code of Federal Regulations, 2013 CFR

...REQUIREMENTS; AND OTHER ACTIONS BASED ON OWNERSHIP, CONTROL, AND VIOLATION...regulatory authorities and other actions based on ownership, control, and violation...written preliminary finding must be based on evidence sufficient to establish a...

2013-07-01

67

Evaluation of the safety and efficacy of micafungin in Japanese patients with deep mycosis: a post-marketing survey report  

Microsoft Academic Search

The safety and efficacy of micafungin were evaluated in a Japanese post-marketing survey involving 1,142 patients with deep\\u000a mycosis caused by Candida or Aspergillus. The overall clinical response was 83.0%, and the respective responses for patients with candidiasis or aspergillosis were\\u000a 86.3 and 70.8%. With regard to drug reactions, 562 adverse reactions were observed in 28.5% of patients. Among the

Tomoko Hanadate; Masahiro Wakasugi; Keizo Sogabe; Toshimitsu Kobayashi; Hisanori Horita; Ikuo Kawamura; Yasuhiro Hori; Keita Matsui; Yo Hoshino; Masahiro Sou

68

Institutional Response to Ohio's Campus Safety Initiatives: A Post-Virginia Tech Analysis  

ERIC Educational Resources Information Center

The purpose of this study was to examine how institutions of higher education were responding to unprecedented state involvement in campus safety planning and policymaking in the aftermath of the Virginia Tech tragedy. Focused on Ohio, a state in which a state-level task force was convened and charged to promulgate campus safety recommendations…

Jackson, Natalie Jo

2009-01-01

69

Institutional Response to Ohio's Campus Safety Initiatives: A Post-Virginia Tech Analysis  

ERIC Educational Resources Information Center

|The purpose of this study was to examine how institutions of higher education were responding to unprecedented state involvement in campus safety planning and policymaking in the aftermath of the Virginia Tech tragedy. Focused on Ohio, a state in which a state-level task force was convened and charged to promulgate campus safety recommendations…

Jackson, Natalie Jo

2009-01-01

70

Not that soft or informal: a response to Eberlein and Grande's account of regulatory governance in the EU with special reference to the European Food Safety Authority (EFSA)  

Microsoft Academic Search

This article is concerned with the dynamics of an increasingly complex and differentiated European regulatory state. It embraces the concept of ‘regulatory regime’ but asserts that this notion needs to be developed further if it is to capture both the complexity and the dynamism of regulatory bodies, including the European Food Safety Authority. The article takes issue with Eberlein and

Ed Randall

2006-01-01

71

Methodological characteristics of the national dietary surveys carried out in the European Union as included in the European Food Safety Authority (EFSA) Comprehensive European Food Consumption Database  

Microsoft Academic Search

In 2009 competent organisations in the European Union provided the European Food Safety Authority (EFSA) with data from the most recent national dietary survey at the level of individuals’ consumption. Twenty different Member States provided EFSA with data from 22 different national dietary surveys, with consumption figures for adults and, when available, for children. Member States’ dietary data were assembled

C. Merten; P. Ferrari; M. Bakker; A. Boss; Á. Hearty; C. Leclercq; O. Lindtner; C. Tlustos; P. Verger; J. L. Volatier; D. Arcella

2011-01-01

72

A study on the mechanical stress relieving and safety assessment without post-weld heat treatment  

Microsoft Academic Search

For full welded body valve, the temperature of grommet cannot exceed 150°C in order to prevent it from damaging and assure the tightness and the service life of valve. Therefore, post-weld heat treatment (PWHT) cannot be used to relieve the residual stresses. In this study, the effect of the mechanical stress relieving (MSR) treatment on the residual stresses was studied

Jijin Xu; Ligong Chen; Chunzhen Ni

2007-01-01

73

Post-marketing surveillance of the safety and effectiveness of tacrolimus in 3,267 Japanese patients with rheumatoid arthritis.  

PubMed

OBJECTIVES: A post-marketing surveillance (PMS) program was implemented to assess the safety and effectiveness of tacrolimus (TAC) in Japanese rheumatoid arthritis (RA) patients and to identify risk factors related to adverse drug reactions (ADRs). METHODS: Patients were registered centrally and monitored for all adverse events (AEs) for 24 weeks. Effectiveness was evaluated using the Disease Activity Score 28-CRP (DAS28-CRP). RESULTS: Data from 3,172 patients (mean age 62.2 years) were evaluated in the safety analysis. Of the safety population, 78.5 %were female and 25.9 % were in Steinbrocker's functional class 3 or 4. TAC was prescribed as monotherapy in 52.5 % and the most common concomitant disease modifying antirheumatic drug (DMARD) was methotrexate, used in 28.9 % of the patients. The incidence of AEs, serious AEs (SAEs), ADRs and serious ADRs were 41.2, 6.4, 36.0, and 4.9 %, respectively. The most frequent serious ADR category was infections and infestations. Age ?65 years, concurrent renal dysfunction, and concurrent diabetes mellitus were identified as significant risk factors for ADR. Based on EULAR response criteria, 65.4 % of the patients showed moderate or good response. CONCLUSIONS: The results demonstrate that TAC is well tolerated by Japanese patients with active RA, including those receiving concomitant methotrexate, in the real world. PMID:23670404

Takeuchi, Tsutomu; Kawai, Shinichi; Yamamoto, Kazuhiko; Harigai, Masayoshi; Ishida, Kota; Miyasaka, Nobuyuki

2013-05-14

74

An update on the safety and tolerability of pimecrolimus cream 1%: evidence from clinical trials and post-marketing surveillance.  

PubMed

In this report, we review the data on the safety and tolerability of pimecrolimus cream 1% (Elidel) from clinical trials and post-marketing surveillance in patients with atopic dermatitis. These data demonstrate that topically applied pimecrolimus is minimally absorbed through the skin and has a favourable safety margin. The most common treatment-related adverse events are transient local reactions, particularly skin burning (16.1 and 12.9 events per 1,000 patient-months of follow-up in adults and children, respectively). When compared to the vehicle, the use of pimecrolimus cream 1% is associated with an increased incidence of herpes simplex virus infections in children (relative risk: 2.5; 95% confidence interval: 1.2-5.8; p = 0.017). However, pimecrolimus cream 1% does not increase the incidence of any skin infection in comparison with moderately potent topical corticosteroids and lacks other corticosteroid-related side effects such as skin atrophy. While cases of malignancy have been reported in patients who have used pimecrolimus cream 1%, there is no clinical evidence to establish that treatment with pimecrolimus cream 1% increases the risk of malignancy. PMID:18174691

Langley, Richard G B; Luger, Thomas A; Cork, Michael J; Schneider, Dirk; Paul, Carle

2007-12-18

75

Human pregnancy safety for agents used to treat rheumatoid arthritis: adequacy of available information and strategies for developing post-marketing data  

PubMed Central

For female patients with rheumatoid arthritis, the availability of a host of new disease modifying antirheumatic drugs has raised important questions about fetal safety if a woman becomes pregnant while she is being treated. In addition, there is limited safety information regarding many of the older medications commonly used to treat rheumatoid arthritis in women of reproductive age. Current summary pregnancy risk information for selected medications used to treat rheumatoid arthritis is reviewed in the context of the pregnancy label category. In addition, the strengths and weaknesses of post-marketing strategies for developing new pregnancy safety information are described.

Chambers, Christina D; Tutuncu, Zuhre N; Johnson, Diana; Jones, Kenneth L

2006-01-01

76

Public investment in strengthening Veterinary Services and other food safety authorities: issues affecting developed and developing countries.  

PubMed

During the negotiation of the Agreement on the Application of Sanitary and Phytosanitary Measures (the SPS Agreement), there was clear recognition of the problems that developing countries would face in complying with the SPS Agreement. The agreement included provisions related to technical assistance and special differential treatment for developing countries. Both topics are discussed in the SPS Committee as a regular agenda item and have been subject to substantive consideration during both reviews of the SPS Agreement, in 1999 and latterly in 2005. The SPS Committee is currently considering proposals to make these provisions more precise, effective and operational. The Standards and Trade Development Facility (STDF) was formally established in mid-2002 by the Food and Agriculture Organization, World Organisation for Animal Health (OIE), World Bank, World Health Organization and World Trade Organization as a financing and coordinating mechanism. The STDF maintains a database which provides information on SPS-related technical assistance and capacity-building projects. From the limited data gathered, it would appear that the focus of the technical assistance provided so far has been knowledge transfer. Only a small minority of the projects reported deal with the strengthening of hard infrastructure such as laboratory facilities. It is also clear that in terms of the overall number and value of projects, animal health lags well behind the food safety sector. The World Bank estimates that annual expenditure by donor agencies on trade-related SPS programmes has been running at some USdollars 65 million to USdollars 70 million annually. However, there is under-reporting of technical cooperation activities in the STDF database. PMID:17094711

Roberts, M

2006-08-01

77

41 CFR 302-9.175 - When I am authorized to transport a POV, including a replacement POV, to my post of duty...  

Code of Federal Regulations, 2012 CFR

...post of duty subsequent to the time of my assignment to that post...Property Management Federal Travel Regulation System RELOCATION...Transportation Subsequent to the Time of Assignment § 302-9...post of duty subsequent to the time of my assignment to that...

2012-07-01

78

Post-test examination observations for the W-2 SLSF experiment. [Sodium Loop Safety Facility  

SciTech Connect

Gamma scanning measurements revealed that the axial power profile in these test trains was more peaked than expected based on pretest calculations and critical facility measurements. These results implied that the thermal flux incident on the test assembly was greater than expected, which was manifested in highly skewed and extensive fuel melting zones in the outer pin fuel pellets. Observations indicated that the extent of fuel melting near the midplane exceeded 90% of the pellet radius in some of the outer fuel pins toward the end of the overpower transient, with penetration of molten fuel to the cladding inner surface. It is postulated that this extensive fuel melting and penetration combined with bowing-induced high temperature oscillations to produce the initial disruptive failure in an outer pin at the midplane. Subsequent failure events were induced by the inrush of argon fill gas following rupture of the fluted duct tube. Up to one-third of the total fuel inventory was expelled from the test pin bundle into the coolant channels, with substantial upward sweepout of the ejected fuel noted in the post-test examination. The overall nature of the failure event was judged to be relatively nonviolent, based largely on the survival of unclad, free standing fuel pellet columns in the upper levels of the test section. The observed midplane failure in the W-2 experiment has been attributed to conditions unique to the test. These conditions would not exist in full-size LMFBR fuel assemblies, for which fuel pin failure under slow, unprotected TOP conditions would be expected by a different mode at a higher elevation.

Pitner, A.L.; Smith, D.E; Culley, G.E.

1983-09-01

79

Efficacy and Safety of As-Needed, Post Bedtime Dosing with Indiplon in Insomnia Patients with Chronic Difficulty Maintaining Sleep  

PubMed Central

Objective: To evaluate the efficacy and tolerability of immediate release indiplon capsules in patients with chronic insomnia using an “as-needed” dosing strategy in response to difficulty falling back to sleep following a middle of the night, nocturnal awakening. Methods: Adult outpatients (N=264; 71% female; age, 46 years) who met DSM-IV criteria for primary insomnia, with average total sleep time (TST) <6.5 hours and >8 nights in the past month with nocturnal awakenings, were randomized to 4 weeks of double-blind treatment with 10mg or 20mg indiplon capsules, or placebo. The primary endpoint was latency to sleep onset post-dosing after a middle of the night awakening (LSOpd). Secondary endpoints included patients' subjective assessment of total sleep time (sTSTpd). Next day residual effects were evaluated by a 100mm Visual Analog Scale (VAS) rating of sleepiness. Results: Both doses of indiplon significantly reduced LSOpd at all time-points. Compared to placebo (45.2 min), the 4-week least squares (LS) mean LSOpd was 36.5 min in the indiplon 10mg group (P=0.0023) and 34.4 min in the indiplon 20mg group (P<0.0001). The 4-week LS mean sTSTpd was higher in the indiplon 10mg group (253 min) and 20mg group (278 min) compared to placebo (229 min; P<0.01 for both comparisons). There was no increase observed in VAS ratings of next-day sleepiness for either dose of indiplon when compared to placebo. Indiplon was well-tolerated at both doses. Conclusions: Patients with chronic insomnia with nocturnal awakenings achieved significant and sustained improvement in sleep parameters while utilizing an as-needed post bedtime dosing strategy with indiplon capsules. Indiplon was well-tolerated, with no self-rated, next-day residual effects. Citation: Roth T; Zammit GK; Scharf MB; Farber R. Efficacy and safety of as-needed, post bedtime dosing with indiplon in insomnia patients with chronic difficulty maintaining sleep. SLEEP 2007;30(12):1731-1738.

Roth, Thomas; Zammit, Gary K.; Scharf, Martin B.; Farber, Robert

2007-01-01

80

An Algorithm for Mining Adverse-Event Datasets for Detection of Post Safety Concern of a Drug  

Microsoft Academic Search

Signal detection from Adverse Event Reports (AERs) is important for identifying and analysing drug safety concern after a drug has been released into the market. A safety signal is defined as a possible causal relation between an adverse event and a drug. There are a number of safety signal detection algorithms available for detecting drug safety concern. They compare the

Debashis Biswas

2010-01-01

81

[Safety and efficacy of docetaxel in prostate cancer patients: based on the post-marketing surveillance in Japan].  

PubMed

The safety and efficacy of docetaxel in prostate cancer were evaluated based on the results of post-marketing surveillance. 149 patients were enrolled between September 2008 and May 2010. The starting dose of docetaxel was 75 mg/m˛ in 53 patients(36%), 70 mg/m˛ in 55 (37%), and ? 60 mg/m˛ in 41(28%). The median number of treatment cycles was 8 (range, 1 to 10). There was no age difference observed in the starting doses and the treatment cycles. The most common ? grade 3 adverse drug reactions (ADRs) were neutropenia (71%)and leukocytopenia (51%), and they occurred more frequently in patients receiving ? 70 mg/m˛. However, the multi-variate analyses revealed that ? grade 3 ADRs did not correlate with the starting doses. Infection-related events (? grade 3) and interstitial pneumonia were observed in 15% and 1% of patients, respectively. Prostate-specific-antigen (PSA) flare appeared in 19% of 95 evaluable patients at median period of 26 days from treatment initiation. It continued with median duration of 39. 5 days. PSA response rate as defined ? 50% level decline was 37%(95%confidence interval: 27-47) in evaluable patients. It was low in patients receiving ? 60 mg/m˛ (18%). There was no notable difference between patients with initial dose of 75 and 70 mg/m˛. Further investigation for the longer term is warranted. PMID:22504677

Mera, Takeshi; Saijo, Nagahiro; Akaza, Hideyuki

2012-04-01

82

47 CFR 0.392 - Authority delegated.  

Code of Federal Regulations, 2012 CFR

...Delegations of Authority Public Safety and Homeland Security Bureau § 0.392 Authority...delegated. The Chief, Public Safety and Homeland Security Bureau, is hereby delegated... (a) The Chief, Public Safety and Homeland Security Bureau shall not have...

2012-10-01

83

49 CFR 198.11 - Grant authority.  

Code of Federal Regulations, 2012 CFR

...HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY REGULATIONS FOR GRANTS TO AID STATE PIPELINE SAFETY PROGRAMS Grant Allocation § 198.11 Grant authority. The pipeline safety laws (49...

2012-10-01

84

41 CFR 302-9.171 - If circumstances warrant an authorization to transport a POV to my post of duty after my...  

Code of Federal Regulations, 2011 CFR

...Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES... Pov Transportation Subsequent to the Time of Assignment § 302-9.171 If...provided a service agreement was signed at the time of your assignment to the post of...

2011-07-01

85

41 CFR 302-9.171 - If circumstances warrant an authorization to transport a POV to my post of duty after my...  

Code of Federal Regulations, 2012 CFR

...Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES... Pov Transportation Subsequent to the Time of Assignment § 302-9.171 If...provided a service agreement was signed at the time of your assignment to the post of...

2012-07-01

86

Post-marketing safety monitoring of a new group B meningococcal vaccine in New Zealand, 2004-2006.  

PubMed

New Zealand introduced a new outer membrane vesicle vaccine in 2004 to combat an epidemic of group B meningococcal disease. An Independent Safety Monitoring Board oversaw intensive safety monitoring, which included hospital surveillance, health professional reporting (passive and active) and mortality monitoring. With over three million doses administered to individuals aged under 20 years, the monitoring results provide consistent evidence supporting the vaccine's safety. PMID:17660718

McNicholas, Anne; Galloway, Yvonne; Stehr-Green, Paul; Reid, Stewart; Radke, Sarah; Sexton, Kerry; Kieft, Charlotte; Macdonald, Claire; Neutze, Jocelyn; Drake, Ross; Isaac, Dorothy; O'Donnell, Mary; Tatley, Michael; Oster, Philipp; O'Hallahan, Jane

2007-05-18

87

Methodological characteristics of the national dietary surveys carried out in the European Union as included in the European Food Safety Authority (EFSA) Comprehensive European Food Consumption Database.  

PubMed

In 2009 competent organisations in the European Union provided the European Food Safety Authority (EFSA) with data from the most recent national dietary survey at the level of individuals' consumption. Twenty different Member States provided EFSA with data from 22 different national dietary surveys, with consumption figures for adults and, when available, for children. Member States' dietary data were assembled into the EFSA Comprehensive European Food Consumption Database. In this paper an overview of the methodologies and protocols employed in the different national dietary surveys is provided. Specifically, details about dietary assessment methods, interview administration, sampling design, portion size estimation, dietary software, evaluation of under-reporting and non-dietary information collected are described. This information is crucial to evaluate the level of accuracy of food consumption data and to anticipate and acknowledge the utmost important sources of heterogeneity of national databases included in the Comprehensive Database. The Comprehensive Database constitutes a unique resource for the estimation of consumption figures across the European Union and represents a useful tool to assess dietary exposure to hazardous substances and nutrient intake in Europe. Nevertheless, the many substantial methodological differences that characterise the Comprehensive Database are acknowledged and critically discussed. PMID:21732710

Merten, C; Ferrari, P; Bakker, M; Boss, A; Hearty, A; Leclercq, C; Lindtner, O; Tlustos, C; Verger, P; Volatier, J L; Arcella, D

2011-07-06

88

An evaluation of efficacy and safety of reboxetine in elderly patients affected by “retarded” post-stroke depression  

Microsoft Academic Search

Depression occurs frequently in post-stroke patients and appears to be associated with an impairment in their rehabilitation and functional recovery. Although selective serotonin reuptake inhibitors (SSRI) are often used in post-stroke depression (PSD), it has been observed that only a subset of patients is responsive to this treatment. Other patients respond to tricyclic antidepressants or MAO inhibitors, which, however, may

Liborio Rampello; Alessandro Alvano; Santina Chiechio; Rocco Raffaele; Ignazio Vecchio; Mariano Malaguarnera

2005-01-01

89

Index to Nuclear Safety: A Technical Progress Review by Chronology, Permuted Title, and Author, Volume 11(1) through Volume 21(6).  

National Technical Information Service (NTIS)

This index to Nuclear Safety covers articles published in Nuclear Safety, Vol. 11, No. 1 (January-February 1970 through Vol. 21, No. 6 (November-December 1980). The index is divided into three sections: a chronological list of articles (including abstract...

W. B. Cottrell M. Passiakos

1981-01-01

90

Index to Nuclear Safety: A Technical Progress Review by Chronology, Permuted Title, and Author, Volume 11(1) through Volume 20(6).  

National Technical Information Service (NTIS)

This index to Nuclear Safety, a bimonthly technical progress review, covers articles published in Nuclear Safety, Vol. II, No. 1 (January-February 1970), through Vol. 20, No. 6 (November-December 1979). It is divided into three sections: a chronological l...

W. B. Cottrell M. Passiakos

1980-01-01

91

77 FR 52633 - Public Safety and Homeland Security Bureau Seeks Comment on Post-Reconfiguration 800 MHz Band...  

Federal Register 2010, 2011, 2012, 2013

...800 MHz Band Plan Along the U.S.-Mexico Border AGENCY: Federal Communications...band channel plans along the U.S.-Mexico border. The Public Safety and Homeland...MHz channel plans along the U.S.-Mexico border. DATES: Comments are due on...

2012-08-30

92

Assessment of the safety of US nuclear weapons and related nuclear test requirements: A post-Bush Initiative update  

Microsoft Academic Search

The Nuclear Weapons Reduction Initiative announced by President Bush on September 27, 1991, is described herein as set forth in Defense Secretary Cheney`s Nuclear Arsenal Reduction Order issued September 28, 1991. The implications of the Bush Initiative for improved nuclear weapons safety are assessed in response to a request by US Senators Harkin, Kennedy, and Wirth to the Lawrence Livermore

Kidder

1991-01-01

93

Health and safety conditions of building maintenance sites in Nigeria: Evaluating the post occupancy contaminations of timber buildings by microorganisms  

Microsoft Academic Search

This research assessed the safety of the environmental conditions of timber buildings as maintenance sites from cultivable microorganisms under various climatic conditions in Nigeria. Several site illnesses leading to poor work and reduced productivity on construction sites have been attributed to unidentified microorganisms or their metabolites. To identify the microorganisms, bulk samples were collected on timber buildings classified as maintenance

I. H. Mshelgaru; O. S. Olonitola

2010-01-01

94

Intellectual Authority and Institutional Authority.  

ERIC Educational Resources Information Center

|This essay examines the idea of intellectual authority as reflected in legal and literary theory and reviews empirical studies of effects of institutional authority on acceptance/rejection of papers by juried journals. It refutes ideas of Stanley Fish that an author's background (his/her "institutional authority") are relevant in evaluating the…

Collier, Charles W.

1992-01-01

95

Surveillance for adverse events following receipt of pandemic 2009 H1N1 vaccine in the Post-Licensure Rapid Immunization Safety Monitoring (PRISM) System, 2009-2010.  

PubMed

The Post-Licensure Rapid Immunization Safety Monitoring (PRISM) system is a cohort-based active surveillance network initiated by the US Department of Health and Human Services to supplement preexisting and other vaccine safety monitoring systems in tracking the safety of monovalent pandemic 2009 H1N1 influenza vaccine in the United States during 2009-2010. PRISM investigators conducted retrospective analysis to determine whether 2009 H1N1 vaccination was associated with increased risk of any of 14 prespecified outcomes. Five health insurance and associated companies with 38 million members and 9 state/city immunization registries contributed records on more than 2.6 million doses of 2009 H1N1 vaccine. Data on outcomes came from insurance claims. Complementary designs (self-controlled risk interval, case-centered, and current-vs.-historical comparison) were used to optimize control for confounding and statistical power. The self-controlled risk interval analysis of chart-confirmed Guillain-Barré syndrome found an elevated but not statistically significant incidence rate ratio following receipt of inactivated 2009 H1N1 vaccine (incidence rate ratio = 2.50, 95% confidence interval: 0.42, 15.0) and no cases following live attenuated 2009 H1N1 vaccine. The study did not control for infection prior to Guillain-Barré syndrome, which may have been a confounder. The risks of other health outcomes of interest were generally not significantly elevated after 2009 H1N1 vaccination. PMID:22582207

Yih, W Katherine; Lee, Grace M; Lieu, Tracy A; Ball, Robert; Kulldorff, Martin; Rett, Melisa; Wahl, Peter M; McMahill-Walraven, Cheryl N; Platt, Richard; Salmon, Daniel A

2012-05-11

96

Safety and efficacy of ketorolac tromethamine 0.4% ophthalmic solution in post-photorefractive keratectomy patients  

Microsoft Academic Search

Purpose: To evaluate the safety and analgesic efficacy of ketorolac tromethamine 0.4% ophthalmic solution in postoperative photorefractive keratectomy (PRK) patients.Setting: Fifteen clinical sites in the eastern and southern United States.Methods: This pooled analysis of 2 multicenter, randomized, double-masked, vehicle-controlled, parallel-group studies comprised 313 patients having unilateral PRK. After surgery, patients were treated with 1 drop of ketorolac tromethamine 0.4% ophthalmic

Kerry D Solomon; Eric D Donnenfeld; Michael Raizman; Helga P Sandoval; Katherine Stern; Amanda VanDenburgh; Janet K Cheetham; Rhett Schiffman

2004-01-01

97

Patient Safety Organizations  

MedlinePLUS

... mail Updates Welcome to AHRQ's Patient Safety Organization Web Site The Patient Safety and Quality Improvement Act of 2005 (Patient Safety Act) authorized the creation of Patient Safety Organizations (PSOs) to improve the ...

98

Safety and Tolerability of Adjunctive Aripiprazole in Major Depressive Disorder: A Pooled Post Hoc Analysis (studies CN138-139 and CN138-163)  

PubMed Central

Objective: To evaluate the safety and tolerability of aripiprazole adjunctive to standard antidepressant therapy (ADT) for patients with major depressive disorder (DSM-IV-TR criteria). Method: Data from 2 identical studies of aripiprazole augmentation (8 weeks of prospective ADT treatment followed by 6 weeks of randomized double-blind adjunctive treatment) were pooled. The incidence of treatment-emergent adverse events (TEAEs) and weight, electrocardiogram (ECG), and laboratory measurements were assessed during the 6-week phase, including time course, severity, resolution, and predictors. The studies were conducted from June 2004 to April 2006 and September 2004 to December 2006. Results: The safety analysis included 737 outpatients (aripiprazole, n = 371; placebo, n = 366). The majority of patients completed the trials (aripiprazole, 86%; placebo, 88%). Common TEAEs (? 5% and twice the placebo rate) with aripiprazole were akathisia (25%), restlessness (12%), insomnia (8%), fatigue (8%), blurred vision (6%), and constipation (5%). Most TEAEs were of mild to moderate severity (aripiprazole, 89%; placebo, 95%). TEAE rates in the aripiprazole and placebo groups were not affected by ADT, age, or gender. Discontinuation due to TEAEs was low (aripiprazole, 3%; placebo, 1%). Mean weight change was higher with aripiprazole versus placebo (1.73 kg vs 0.38 kg, P < .001). At endpoint, clinical laboratory parameters, vital signs, and ECG indices (including QTc interval) were similar between groups. Akathisia with aripiprazole generally occurred in the first 3 weeks (76%), was of mild to moderate severity (92%), and led to discontinuation in 3 patients (0.8%). Within the aripiprazole group, age (18–40 years) was the only positive predictor for akathisia. Conclusions: In this short-term post hoc analysis, aripiprazole as augmentation to ADT demonstrated a safety and tolerability profile similar to that in monotherapy studies in other psychiatric populations. Controlled long-term safety and efficacy data of aripiprazole as adjunctive to ADT are warranted. Trial Registration: clinicaltrials.gov Identifiers: NCT00095823 (CN138-139) and NCT00095758 (CN138-163)

Thase, Michael E.; Trivedi, Madhukar H.; Fava, Maurizio; Han, Jian; Van Tran, Quynh; Pikalov, Andrei; Qi, Ying; Carlson, Berit X.; Marcus, Ronald N.; Berman, Robert M.

2009-01-01

99

The flawed basis for FDA post-marketing safety decisions: the example of anti-depressants and children.  

PubMed

The FDA (February 3, 2005) issued a black box warning that all antidepressants increase the risk of suicidal thinking and behavior in children and adolescents that must be cited in all advertising as well as included in the package insert. Following this, there was a sharp decrease in antidepressant prescriptions for children with uncertain public health impact. The current black box does not claim that these medications increase the risk of completed suicides, although this is the clear implication of the term 'suicidality'. The interpretation by the press is unequivocal that lethal outcomes prompted this action. This review concludes the following: (1) Since no suicide occurred in clinical trials of approximately 4400 children, the analyses relied upon 'suicidality' as a surrogate. (2) The classification of adverse events by the Columbia group necessarily relied on inferences, because the available evidence was not prospectively collected for this purpose. (3) The data analysis relied on a composite variable labeled 'suicidality', an unvalidated, inappropriate surrogate. Specific criticisms of analytic procedures and inferences are presented. The failure of the FDA's post-marketing surveillance system is reviewed. The data necessary for objective evaluations of possible post-marketing harm cannot be gathered by the current process. Proper prospective post-marketing surveillance by linked computerized medical records is a crucial issue that deserves major public and political attention and prompt action. PMID:16395296

Klein, Donald F

2006-04-01

100

49 CFR Appendix to Subpart H of... - Explanation of Pre-Authorization Safety Audit Evaluation Criteria for Non-North America-Domiciled...  

Code of Federal Regulations, 2010 CFR

...accident; or one or more motor vehicles incurring disabling...accident requiring the motor vehicle to be transported...a tow truck or other motor vehicle. (2) [Reserved...basic safety management controls in Factor 6, Accident...avoided it by taking steps within his/her...

2010-10-01

101

49 CFR Appendix to Subpart H of... - Explanation of Pre-Authorization Safety Audit Evaluation Criteria for Non-North America-Domiciled...  

Code of Federal Regulations, 2010 CFR

...accident; or one or more motor vehicles incurring disabling...accident requiring the motor vehicle to be transported...a tow truck or other motor vehicle. (2) [Reserved...basic safety management controls in Factor 6, Accident...avoided it by taking steps within his/her...

2009-10-01

102

H. R. 2092(Report No. 99-121, Parts I, II, and III): a bill to amend the Natural Gas Pipeline Safety Act of 1968 and the Hazardous Liquid Pipeline Safety Act of 1979 to authorize appropriations for fiscal years 1986 and 1987, and for other purposes. Introduced in the House of Representatives, Nineth-Ninth Congress, First Session, April 17, 1985  

SciTech Connect

Parts I, II, and III of the House report amend the Natural Gas Pipeline Safety Act of 1968 and the Hazardous Liquid Pipeline Safety Act of 1979 to preclude discriminatory tax treatment by states and local governments imposing an overvalued assessment against interstate gas transmission for ad valorem taxes. The amendment clarifies assessment terms and stipulates that federal courts may intervene if tax assessments exceed five per cent of true market value. The bill also authorizes the fiscal year 1986 and 1987 appropriations.

Not Available

1985-01-01

103

Methodological approaches to developing and establishing the body of evidence on post-marketing Chinese medicine safety.  

PubMed

Evidence based medicine demands the highest form of scientific evidence to demonstrate the efficacy and clinical effectiveness for any therapeutic intervention in order to provide best care. It is however accepted that in the absence of scientific evidence, personal experience and expert opinion together with professional judgement are critical. Obtaining evidence for drug safety, postmarketing surveillance (PMS) has focussed on follow up of observational cohorts exposed to a particular drug in order to estimate the incidence of adverse drug reactions (ADRs). Evidence on PMS of Chinese herbal products is still limited, in particular for herbal injections. The aim of this article is to suggest a new model of ascertaining the safety of Chinese medicine using a more comprehensive approach for collecting data. To collect safety data on the Chinese herbal injection, Kudiezi, a mixed methods approach is proposed using 18 hospital information systems to detect ADRs in order to prospectively observe 30,000 patients over 3 years. Evidence will also be collected using a questionnaire survey and through a sample of semi structured interviews. This information based on the expert opinion and the experience of clinicians will produce additional data on the frequency and types of side effects in clinical practice. Furthermore semi structured interviews with a random sample of patients receiving the injection will be carried out to ascertain any potential side effects missed. It is hoped that this comprehensive approach to data collection will accumulate wider evidence based on individual traditional Chinese medicine care and treatment and provide important feedback to the national data collection system to ensure completeness of ADR data recording, monitoring and any potential wider effects through developing improved ADR guidelines. PMID:23818200

Liao, Xing; Robinson, Nicola

2013-07-02

104

New concept for immediate breast reconstruction for invasive cancers: feasibility, oncological safety and esthetic outcome of post-neoadjuvant therapy immediate breast reconstruction versus delayed breast reconstruction: a prospective pilot study  

Microsoft Academic Search

Feasibility and oncological safety of post-adjuvant skin-sparing mastectomy (SSM) plus immediate breast reconstruction (IBR)\\u000a cannot be evaluated by randomized trials. However, comparative study could modify guidelines for the oncosurgical treatment\\u000a of invasive breast cancer. Our study compared the feasibility, oncological safety and esthetic outcome of SSM plus latissimus\\u000a dorsi (LD) flap IBR after chemotherapy (CT) and radiotherapy (RT) with the

Pierre Ludovic Giacalone; Gauthier Rathat; Jean Pierre Daures; Paul Benos; David Azria; Caroline Rouleau

2010-01-01

105

Safety and immunogenicity of two freeze-dried Vero cell rabies vaccines for human use in post-exposure prophylaxis.  

PubMed

To provide basis for human rabies vaccination in China, the safety and immunogenicity of two freeze-dried Vero cell rabies vaccines for human use were assessed. A total of 250 volunteers were enrolled and divided into two groups: volunteers in Group A (n=200) were vaccinated five doses of Speeda Vero cell rabies vaccine manufactured by Liaoning Chengda Biotechnology Co. Ltd. on day 0, 3, 7, 14, 28 after exposure. Volunteers in Group B (n=50) were treated with Verorab Vero cell rabies vaccine manufactured by Sanofi Pasteur on the same schedule. The local and systematic adverse reactions were observed. Serum neutralizing antibody levels of 80 individuals in Group A and 50 individuals in Group B were tested with RFFIT on day 7, 14, 45, 180, 360 after the first dose. The seroconversion rates in Groups A and B were 40.3% and 37.0% on day 7 after the first dose, 95.5% and 97.7% on day 14, 100% and 100% on day 45, 100% and 100% on day 180, 89.1% and 89.5% on day 360 respectively, indicating no significant differences between the two groups. And no significant differences were found between the neutralizing antibody geometric mean titers (GMTs) of the two groups on day 7, 14, 45, 180 and 360 after the first dose, with the GMTs of day 14, 45, 180 and 360 all higher than 0.5IU/ml. Antibody levels of the two groups peaked around 2 weeks after the full vaccination program, followed by a 55% decrease up to day 180 and another 76% decrease up to day 360. Both groups experienced occasions of transient fever, rash, edema, and scleroma after vaccination. Neither group had any severe adverse reactions. It was concluded that both vaccines showed satisfactory safety and immunogenicity. Booster vaccination is recommended following another exposure after six months since the full vaccination program. PMID:21296694

Wang, Ling-yun; Sun, Mei-ping; Zhang, Xue-chun; Suo, Luo-dan; Xu, Ruo-hui; Zou, Yan-jie; Zuo, Li-bo; Qi, Hua

2011-02-03

106

Author! Author!”: Shakespeare and biography  

Microsoft Academic Search

Since 1996, not a year has passed without the publication of at least one Shakespeare biography. Yet for many years the place of the author in the practice of understanding literary works has been problematized, and even on occasions eliminated. Criticism reads the “works”, and may or may not refer to an author whose “life” contributed to their meaning. Biography

Graham Holderness

2009-01-01

107

Safety of besifloxacin ophthalmic suspension 0.6% in refractive surgery: a retrospective chart review of post-LASIK patients  

PubMed Central

Background To evaluate the safety of besifloxacin ophthalmic suspension 0.6% when used in laser-assisted in situ keratomileusis (LASIK) prophylactic antibiotic regimens. Methods Retrospective surveillance of LASIK surgery cases where besifloxacin ophthalmic suspension 0.6% or moxifloxacin ophthalmic solution 0.5% were prescribed as prophylactic medications. Surgeons from nine US surgical centers provided retrospective case information on surgical outcomes from consecutive cases and reported any adverse events related to the antibacterial used. The primary endpoint was the incidence of adverse drug reactions. Results A total of 801 case reports (801 eyes; 534 besifloxacin, 267 moxifloxacin) were obtained. The mean (standard deviation [SD]) age at time of surgery was 36.1 (10.6) years. The mean (SD) duration of antibiotic treatment was 8.6 (2.2) days in the besifloxacin group and 8.0 (2.3) in the moxifloxacin group; daily dosing frequency was higher in the moxifloxacin group preoperatively, on the day of surgery, and postoperatively. There were no reports of adverse drug reactions for the 801 eyes in this surveillance. There were no differences between the besifloxacin and moxifloxacin treatment groups in rates of unexpected corneal findings (2.1% vs 1.5%, P = 0.949). The distribution of final visual acuity for the besifloxacin and moxifloxacin groups were similar (P = 0.793). Most cases had a final visual acuity of 20/20 or better. Conclusion In this retrospective surveillance study, the prophylactic use of besifloxacin ophthalmic suspension 0.6% and moxifloxacin ophthalmic solution 0.5% in patients undergoing LASIK surgery was not associated with any adverse drug reactions.

Nielsen, Steven A; McDonald, Marguerite B; Majmudar, Parag A

2013-01-01

108

Author's Guidelines  

Microsoft Academic Search

The process of publication of an article in any magazine or journal can seem quite difficult for aspiring authors. If you intend getting published then you need a knowledge of the requirements of the particular magazine, its readership profile, its style and, obviously, an interesting topic. I have placed the actual content of the article last, not because the content

Mike Grace

2001-01-01

109

Author's Response  

Microsoft Academic Search

The author responds to a selection of the major challenges and questions raised by his colleagues in this volume: How should the limitations presented by the international arena affect one's priorities in designing foreign policy? What role can be played by nonstate actors in building basic security? What is the role of ideology in explaining violent behavior, and what is

Amitai Etzioni

2008-01-01

110

A right hemisphere safety backup at work: hypotheses for deep hypnosis, post-traumatic stress disorder, and dissociation identity disorder.  

PubMed

Problem theory points to an a priori relation between six key problems of living, to which people have adapted through evolution. Children are guided through the problems one by one, learning to switch between them automatically and unawares. The first problem of raising hope of certainty (about the environment), is dealt with in the right hemisphere (RH). The second of raising hope of freedom (or power to control), is dealt with in the left hemisphere (LH). Here adventurousness and ignoring the goodness of outcomes potentially create recklessness. When uncertainty rises the RH activates a backup with an override that substitutes immobility, takes over sensory inputs, but allows obedience to parental commands, and a cut-out that stops new work on the freedom problem. Support for the use of the backup by infants is found in the immobility that precedes the crying in strange conditions, and in childhood EEGs. The hypothesis that the backup is active in deep hypnosis imposes accord on findings that appear contradictory. For example it accounts for why observations during deep hypnosis emphasize the activity of the RH, but observations of responsive people not under hypnosis emphasize the activity of the LH. The hypothesis that the backup is active in post-traumatic stress disorder (PTSD) is supported by (a) fMRI observations that could reflect the cut-out, in that part of the precuneus has low metabolism, (b) the recall of motionlessness at the time of the trauma, (c) an argument that playing dead as a defence against predators is illogical, (d) the ease of hypnosis. With dissociative identity disorder (DID), the theory is consistent with up to six alters that have executive control and one trauma identity state where childhood traumas are re-experienced. Support for the cut-out affecting the trauma identity state comes from suppression of part of the precuneus and other parts of the parietal lobe when the trauma identity state is salient and a general script about a trauma is listened to. Support also comes from the ease of hypnosis. The cut-out acts independently of the override. It is linked to low metabolism at the same point in the left precuneus by evidence from all three conditions, hypnosis, PTSD and DID. The concept of dissociation is not required with any of the hypotheses. PMID:23790686

Burnand, Gordon

2013-06-19

111

Safety Evaluation Report for the Tennessee Valley Authority's Plan to Decommission its Low-Level Radioactive Waste Burial Site at Muscle Shoals, Alabama  

SciTech Connect

From 1966 to 1981, the Tennessee Valley Authority (TVA) operated a burial site, licensed under the former 10 CFR 20.304, for low-level radioactive waste on its Muscle Shoals, Alabama, reservation. TVA submitted a decommissioning plan for the burial site and requested approval for unrestricted use of the site. The Nuclear Regulatory Commission requested Oak Ridge National Laboratory (ORNL) to evaluate this plan to determine if the site meets the radiological requirements for unrestricted use as specified in 10 CFR 20.1402; that is, an average member of the critical group would not receive more than 25 mrem/y from residual radioactivity at the TVA Low-Level Radioactive Waste Burial Site and the radioactivity has been reduced to levels as low as reasonably achievable (ALARA).

Gant, K.S.; Kettelle, R.H.

1998-11-01

112

Post-marketing Safety Evaluation of S-1 in Patients with Inoperable or Recurrent Breast Cancer: Especially in Patients Treated with S-1 + Trastuzumab  

PubMed Central

Objective The purpose of this study was to assess the safety of S-1 in Japanese in inoperable or recurrent breast cancer patients. Methods A prospective post-marketing surveillance was performed at 313 sites in Japan in patients with inoperable or recurrent breast cancer treated with S-1. We examined 1361 patients between January 2006 and December 2007 with regard to the incidence of adverse drug reactions graded by the Common Terminology Criteria for Adverse Events (CTCAE), version 3.0. Results At least one adverse drug reaction was encountered by 858 patients, with an overall incidence of 63.0% (858/1361). The incidence of Grade 3 or higher adverse drug reactions in a descending order was 14.7% (200/1361). In this study, the most common combination drug was trastuzumab. The overall incidence of adverse drug reactions was 63.5% (431/679 patients) in patients treated with S-1 alone, and 55.9% (66/118 patients) in patients treated with S-1 + trastuzumab. Conclusions Monotherapy with S-1 or combination therapy with S-1 + trastuzumab was well tolerated for inoperable or recurrent breast cancer patients.

Saito, Yuki; Oshitanai, Risa; Terao, Mayako; Terada, Mizuho; Tsuda, Banri; Okamura, Takuho; Suzuki, Yasuhiro; Tokuda, Yutaka

2011-01-01

113

Safety and efficacy of fasudil monotherapy and fasudil-ozagrel combination therapy in patients with subarachnoid hemorrhage: sub-analysis of the post-marketing surveillance study.  

PubMed

Sub-analysis of the fasudil post-marketing surveillance study compared the safety and efficacy of fasudil plus ozagrel to fasudil only. A total of 3690 patients received fasudil and 1138 received fasudil plus ozagrel between 1995 and 2000. The occurrence of adverse events, occurrence of low density areas associated with vasospasm on computed tomography, absence of symptomatic vasospasm, and poor clinical outcomes associated with vasospasm were compared between the fasudil and fasudil plus ozagrel groups. The pharmacokinetics of fasudil were assessed in 5 patients with subarachnoid hemorrhage. The drug interaction between fasudil and ozagrel was pharmacologically investigated in vitro and in vivo. The occurrence of adverse events and clinical outcomes were similar between the two groups. The occurrences of symptomatic vasospasm and low density areas were lower in the fasudil group than in the fasudil plus ozagrel group. The average trough value (8-hour value) of the fasudil active metabolite, hydroxyfasudil, was 50 nM. Fasudil showed no pharmacological interaction with ozagrel. The combination of fasudil plus ozagrel was well tolerated, but did not result in better efficacy than fasudil only. PMID:18574328

Suzuki, Yoshio; Shibuya, Masato; Satoh, Shin-ichi; Sugiyama, Hirotoshi; Seto, Minoru; Takakura, Kintomo

2008-06-01

114

Medical Oxygen Safety  

MedlinePLUS

... Medical Oxygen Medical Safety Post “No Smoking” “No Open Flames” in and outside the home to remind people not to smoke. Your Source for SAFETY Information NFPA Public Education Division | www. ...

115

Microbiological Safety Bibliography.  

National Technical Information Service (NTIS)

More than a thousand articles on biological safety in infectious disease laboratories are listed for the use of supervisors responsible for the safety of laboratory personnel. An author index is included. (Author)

G. B. Phillips J. V. Jemski

1965-01-01

116

Post Approval Safety Data Management  

Center for Biologics Evaluation and Research (CBER)

Text Version... relevant published abstracts from meetings and draft ... is determined that the case meets minimum criteria ... receipt of a case meeting minimum criteria ... More results from www.fda.gov/downloads/drugs/guidancecomplianceregulatoryinformation

117

FFTF Authorization Agreement  

SciTech Connect

The purpose of the Authorization Agreement is to serve as a mechanism whereby the U.S. Department of Energy, Richland Operations Office (RL) and Fluor Hanford (FH) jointly clarify and agree to key conditions for conducting work safely and efficiently in the Fast Flux Test Facility (FFTF). Work must be accomplished in a manner that achieves high levels of quality while protecting the environment and the safety and health of workers and the public, and complying with applicable contractual and regulatory requirements. It is the intent of this Agreement to address those items of significant importance in establishing and supporting the FFTF Authorization Envelope, but this Agreement in no way alters the terms and conditions of the Project Hanford Management Contract (PHMC), Contract Number DE-AC06-96RL13200.

DAUTEL, W.A.

2000-09-25

118

Human pregnancy safety for agents used to treat rheumatoid arthritis: adequacy of available information and strategies for developing post-marketing data  

Microsoft Academic Search

For female patients with rheumatoid arthritis, the availability of a host of new disease modifying antirheumatic drugs has raised important questions about fetal safety if a woman becomes pregnant while she is being treated. In addition, there is limited safety information regarding many of the older medications commonly used to treat rheumatoid arthritis in women of reproductive age. Current summary

Christina D Chambers; Zuhre N Tutuncu; Diana Johnson; Kenneth L Jones

2006-01-01

119

Food allergy and intolerance: an international chemical safety perspective 1 The views expressed are those of the author and do not necessarily reflect the decision or stated policy of the World Health Organization. 1  

Microsoft Academic Search

Chemical safety is concerned with the assessment of human health (and environmental) risks and their management. The safety of chemicals in food, present as normal constituents, intentional additives, contaminants or residues is part of chemical safety. Morbidity and mortality due to allergenic chemicals and allergic hypersensitization are being addressed on a global basis. As part of this, international efforts are

Edward Smith

1997-01-01

120

Authors and publication practices.  

PubMed

Although authors are usually considered to be the main perpetrators of research and publication misconduct, any person involved in the process has the potential to offend. Editors may breach ethical standards particularly with respect to conflicts of interest. In the same way that authors are now required to declare competing interests, notably commercial affiliations, financial interests and personal connections, so must editors. Editors can influence the chances of acceptance or rejection of a paper by reviewer selection. Reviewers should also be ready to disclose conflicts of interest. They must ensure that their reviews are evidence based and free from destructive criticism driven by self interest. It seems likely that ultimately we will progressively move towards 'open' peer review in which both the authors and the reviewers are known to each other. There is an urgent need for increased transparency of the relationship between editors and owners. The events of the last few years indicate that unless this interface is fully understood by all parties, conflicts may arise. There is also a need for a radical overhaul in the relationship between journals, journal editors and the biomedical industry. It is now increasingly accepted that all clinical trials should be registered in a centrally held database and that protocols should include the primary and secondary outcome measures and the intended approach to data analysis thereby avoiding opportunistic post hoc analyses. However, the even more radical proposal that journals should cease to publish clinical trials sponsored by industry deserves wider debate. PMID:16501646

Farthing, Michael J G

2006-01-01

121

Safety evaluation report related to the operation of Watts Bar Nuclear Plant, Units 1 and 2, Docket Nos. 50-390 and 50-391, Tennessee Valley Authority. Supplement number 20  

SciTech Connect

This report supplements the Safety Evaluation Report (SER), NUREG-0847 (June 1982), Supplement No. 1 (September 1982), Supplement No. 2 (January 1984), Supplement No. 3 (January 1985), Supplement No. 4 (March 1985), Supplement No. 5 (November 1990), Supplement No. 6 (April 1991), Supplement No. 7 (September 1991), Supplement No. 8 (January 1992), Supplement No. 9 (June 1992), Supplement No. 10 (October 1992), Supplement No. 11 (April 1993), Supplement No. 12 (October 1993), Supplement No. 13 (April 1994), Supplement No. 14 (December 1994), Supplement No. 15 (June 1995), Supplement No. 16 (September 1995), Supplement No. 17 (October 1995), Supplement No. 18 (October 1995), and Supplement No. 19 (November 1995) issued by the Office of Nuclear Reactor Regulation of the US Nuclear Regulatory Commission with respect to the application filed by the Tennessee Valley Authority, as applicant and owner, for licenses to operate the Watts Bar Nuclear Plant, Units 1 and 2 (Docket Nos. 50-390 and 50-391). The facility is located in Rhea County, Tennessee, near the Watts Bar Dam on the Tennessee River. This supplement provides recent information regarding resolution of some of the issues identified in the SER.

NONE

1996-02-01

122

Vaccine safety.  

PubMed

Brief reports are presented on Swissmedic's experiences with PaniFlow, a tool to monitor Adverse Events Following Immunization (AEFI) of pandemic influenza (H1N1) 2009 vaccines and UMC's updates on AEFI of these vaccines; on WHO's Global Network for Post-marketing Surveillance of Prequalified Vaccines and India joining the network; the June 2010 meeting of the Global Advisory Committee on Vaccine Safety. PMID:21673419

Labadie, Jerry

2011-01-01

123

Highway Safety Program Manual: Volume 3: Motorcycle Safety.  

ERIC Educational Resources Information Center

|Volume 3 of the 19-volume Highway Safety Program Manual (which provides guidance to State and local governments on preferred highway safety practices) concentrates on aspects of motorcycle safety. The purpose and specific objectives of a State motorcycle safety program are outlined. Federal authority in the highway safety area and general…

National Highway Traffic Safety Administration (DOT), Washington, DC.

124

Xyzal: Safety Review  

Center for Biologics Evaluation and Research (CBER)

Text Version... The purpose of this review is to provide the Pediatric Advisory Committee (PAC) with post- marketing safety data ... Medical Dictionary for Regulatory ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

125

Safety First!  

ERIC Educational Resources Information Center

|In this article, the author relates how a hands-on chemistry investigation provided her the inspiration to develop an effective safety lesson for her third grade chemistry class. She began the lesson by demonstrating the use of pH indicator paper to show that ordinary household (white) vinegar was an acid. With the students, she wondered aloud…

Longfield, Judith

2006-01-01

126

[The authorization of clinical trials by the federal authorities].  

PubMed

Since 2004, clinical trials of medicinal products have to be approved by the federal authorities in Germany. Authorization is necessary in addition to the favorable opinion of the concerned ethics committee. This procedure has undoubtedly resulted in larger expenditures with respect to time and costs of planning and conducting of clinical trials. However, the implementation of Good Clinical Practice has also increased both safety for the trial subjects and validity of the data. The most important laws and regulations, definitions, the procedures for submitting a clinical trial application as well as subsequent amendments are described and further information is provided. PMID:19266174

Schriever, J; Schwarz, G; Steffen, C; Krafft, H

2009-04-01

127

47 CFR 95.1203 - Authorized locations.  

Code of Federal Regulations, 2011 CFR

... FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PERSONAL RADIO SERVICES Medical Device Radiocommunication Service (MedRadio) § 95.1203 Authorized locations. MedRadio operation is...

2011-10-01

128

48 CFR 23.502 - Authority.  

Code of Federal Regulations, 2012 CFR

...ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Drug-Free Workplace 23.502 Authority. Drug-Free Workplace...

2012-10-01

129

77 FR 50637 - Schedule of Fees Authorized  

Federal Register 2010, 2011, 2012, 2013

...Notice 2] RIN 2127-AL09 Schedule of Fees Authorized AGENCY: National Highway Traffic...SUMMARY: This document adopts fees for Fiscal Year 2013 and until further...vehicle safety standards (FMVSS). These fees are needed to maintain the registered...

2012-08-22

130

Post-Tensioned Glass Beams  

Microsoft Academic Search

At Delft University, glass researchers have developed a revolutionary safety concept for glass beams. This safety concept\\u000a shows some analogy with reinforced concrete; glass beams are reinforced and\\/or post-tensioned by adding (stainless) steel\\u000a to the layout of the beam.

C. Louter; J. van Heusden; F. Veer; J. Vambersky; H. Boer; J. Versteegen

131

10 CFR 76.81 - Authorized use of radioactive material.  

Code of Federal Regulations, 2010 CFR

...Authorized use of radioactive material. 76.81 Section 76... CERTIFICATION OF GASEOUS DIFFUSION PLANTS Safety § 76.81 Authorized use of radioactive material. Unless otherwise authorized...possession and use of radioactive material to the locations...

2009-01-01

132

10 CFR 76.81 - Authorized use of radioactive material.  

Code of Federal Regulations, 2010 CFR

...Authorized use of radioactive material. 76.81 Section 76... CERTIFICATION OF GASEOUS DIFFUSION PLANTS Safety § 76.81 Authorized use of radioactive material. Unless otherwise authorized...possession and use of radioactive material to the locations...

2010-01-01

133

Post tracheal extubation stridor  

PubMed Central

The authors report an unusual case of post extubation stridor resulting in insertion of a tracheostomy. Regional anaesthesia using interscalene nerve blockade in the presence of an unrecognised contralateral recurrent laryngeal nerve palsy resulted in bilateral recurrent laryngeal nerve palsies. The authors discuss the differential causes of stridor and recurrent laryngeal nerve palsy, their importance and way of identification on preoperative assessment.

Hollister, Nigel; Altemimi, Harith; West, Martyn

2011-01-01

134

Post tracheal extubation stridor.  

PubMed

The authors report an unusual case of post extubation stridor resulting in insertion of a tracheostomy. Regional anaesthesia using interscalene nerve blockade in the presence of an unrecognised contralateral recurrent laryngeal nerve palsy resulted in bilateral recurrent laryngeal nerve palsies. The authors discuss the differential causes of stridor and recurrent laryngeal nerve palsy, their importance and way of identification on preoperative assessment. PMID:22689277

Hollister, Nigel; Altemimi, Harith; West, Martyn

2011-05-16

135

Post Planned Obsolescence  

Microsoft Academic Search

How to extend product life circle through innovative design is the responsibility of designer. Through analyzing the reasonable content in żPlanned Obsolescenceż and the series design of Ricoh R digital camera, the author bring forward to the product series design model of żpost planned obsolescenceż. The author points that feature is the core of the model, and technology, function and

Wei Sun; Ping Sun

2008-01-01

136

48 CFR 605.502 - Authority.  

Code of Federal Regulations, 2012 CFR

...PUBLICIZING CONTRACT ACTIONS Paid Advertisements 605.502 Authority. (a) For paid advertisements in newspapers within the United...by overseas posts necessitating paid advertisements in newspapers outside the...

2012-10-01

137

48 CFR 605.502 - Authority.  

Code of Federal Regulations, 2011 CFR

...PUBLICIZING CONTRACT ACTIONS Paid Advertisements 605.502 Authority. (a) For paid advertisements in newspapers within the United...by overseas posts necessitating paid advertisements in newspapers outside the...

2011-10-01

138

Efficacy and safety of growth hormone replacement therapy in Japanese adults with growth hormone deficiency: a post-marketing observational study.  

PubMed

This large-scale observational study examined the long-term effectiveness and safety of growth hormone (GH) replacement therapy for adult GH deficiency (GHD) in Japanese clinical practice using the Hypopituitary Control and Complications Study database. The study included 402 GHD patients for safety analyses and a subset of 209 patients (149 adult-onset and 60 childhood-onset GHD patients) who had not previously received GH replacement therapy for the efficacy analyses. Data on clinical, metabolic, quality of life (QoL) characteristics, and all adverse events (AEs) were collected at baseline (start of GH treatment), 6 months, 1 year and 2 years. Over the observation period, there were improvements from baseline in insulin-like growth factor-I standard deviation scores (P < 0.001), although the changes in metabolic parameters were minimal. QoL (Short Form-36) Z-scores significantly increased from baseline in both onset-type groups for several subscale domains (P < 0.05). A total of 145 (36.1%) patients experienced ?1 AE. Common AEs were hyperlipidaemia (2.7%) and hyperinsulinaemia (2.2%). Some patients experienced recurrent hypothalamic/pituitary tumour (events per 1000 patient-years: 2.78), new benign (0.93), malignant tumour (10.28) or other new tumour (0.93), new diabetes mellitus (7.45), and new stroke (3.71). Seven patients died during the observation period. Our safety findings are inconclusive about the associations between GH replacement and AEs, although the incidence of diabetes mellitus and cardiovascular events are similar to those reported in the Japanese general population. In conclusion, the key beneficial effects of GH replacement therapy for GHD are observed in routine clinical practice in Japan. PMID:23823978

Shimatsu, Akira; Tai, Shigeru; Imori, Makoto; Ihara, Katsuichiro; Taketsuna, Masanori; Funai, Jumpei; Tanaka, Toshiaki; Teramoto, Akira; Irie, Minoru; Chihara, Kazuo

2013-07-04

139

[Evidences of safety and tolerability of the zoledronic acid 5 mg yearly in the post-menopausal osteoporosis: the HORIZON project].  

PubMed

Bisphosphonates are the most commonly prescribed medications for the treatment of osteoporosis. Despite evidence supporting the anti-fracture efficacy of aminobisphosphonates approximately 50% of patients do not follow their prescribed treatment regimen and/or discontinue treatment within the first year. Poor compliance is associated with negative outcomes, including increased fracture risk. Tolerability and safety are among the causes of poor compliance. Intravenous bisphosphonates avoids the gastrointestial intolerance and the complex dosing instruction of the oral route ensuring full compliance which may provide improved efficacy. However, there are some concerns regarding potent intravenous bisphosphonates as zoledronic acid with respect to tolerability, mainly the acute phase response and to safety, mainly a theoretical risk of over suppression of bone turnover, renal toxicity and osteonecrosis of the jaw. In the HORIZON study, 152 patients on active treatment (82) or placebo (70) underwent to a bone biopsy after double tetracycline labeling. Bone biopsies (iliac crest) were obtained at the final visit at month 36, 1 year after the last infusion. The biopsies were analyzed by histomorphometry on bone sections and by micro-CT (microCT) analysis. One hundred forthy-three biopsies (76 zoledronic acid, 67 placebo) had at least one microCT parameter measured and 111 were available for quantitative histomorphometry (59 zoledronic acid, 52 placebo). Micro-CT analysis of bone structure revealed higher trabecular bone volume (BV/TV), decreased trabecular separation (Tb.Sp), and a strong trend towards improvement in connectivity density in biopsies obtained from patients treated with zoledronic acid, indicating preservation of trabecular bone structure with respect to placebo. Histomorphometric analysis obtained from patients treated with zoledronic acid exhibited reduction of bone turnover, as suggested by decreased activation frequency (Ac.F) by 63%, mineralizing surface (MS/BS), bone formation rate (BFR/BV). In addition, mineral appositional rate (MAR), reflecting the bone-forming capacity of osteoblastic teams at the bone multicellular unit (BMU) level, was significantly higher in patients on active treatment. No sign of excessive suppression of bone turnover or mineralization impairment was detected, confirming the safety of the treatment with intravenous zoledronic acid once a year. These interesting findings are discussed in the article, particularly in terms of new histomorphometric results and clinical findings supporting the tolerability and safety of zoledronic acid. PMID:19370189

Dalle Carbonare, L; Bertoldo, F; Lo Cascio, V

140

FDA Regulations No Longer Authorize the Use of BPA in ...  

Center for Food Safety and Applied Nutrition (CFSAN)

... The agency's current safety review supports the safety of BPA for use in the manufacture of food contact articles as authorized in the food additive ... More results from www.fda.gov/food/newsevents/constituentupdates

141

42 CFR 3.416 - Authority to settle.  

Code of Federal Regulations, 2012 CFR

...Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS PATIENT SAFETY ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT Enforcement Program § 3.416 Authority to settle. Nothing in this subpart...

2012-10-01

142

42 CFR 3.514 - Authority to settle.  

Code of Federal Regulations, 2012 CFR

...Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS PATIENT SAFETY ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT Enforcement Program § 3.514 Authority to settle. The Secretary has...

2012-10-01

143

42 CFR 3.416 - Authority to settle.  

Code of Federal Regulations, 2011 CFR

...Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS PATIENT SAFETY ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT Enforcement Program § 3.416 Authority to settle. Nothing in this subpart...

2011-10-01

144

42 CFR 3.508 - Authority of the ALJ.  

Code of Federal Regulations, 2012 CFR

...Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS PATIENT SAFETY ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT Enforcement Program § 3.508 Authority of the ALJ. (a) The ALJ must...

2012-10-01

145

42 CFR 3.508 - Authority of the ALJ.  

Code of Federal Regulations, 2011 CFR

...Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS PATIENT SAFETY ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT Enforcement Program § 3.508 Authority of the ALJ. (a) The ALJ must...

2011-10-01

146

42 CFR 3.514 - Authority to settle.  

Code of Federal Regulations, 2011 CFR

...Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS PATIENT SAFETY ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT Enforcement Program § 3.514 Authority to settle. The Secretary has...

2011-10-01

147

29 CFR 1903.3 - Authority for inspection.  

Code of Federal Regulations, 2013 CFR

...Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR INSPECTIONS, CITATIONS AND PROPOSED PENALTIES § 1903.3 Authority for inspection. (a) Compliance Safety and Health...

2013-07-01

148

A Multidimensional Examination of Campus Safety: Victimization, Perceptions of Danger, Worry about Crime, and Precautionary Behavior among College Women in the Post-Clery Era  

ERIC Educational Resources Information Center

|Using data from a spring 2004 telephone survey of 1,010 female undergraduate and graduate students at one southeastern state university, the authors examine the objective and subjective experiences with sexual assault or coercion, physical assault, and stalking among college women, paying particular attention to whether actual victimization…

Wilcox, Pamela; Jordan, Carol E.; Pritchard, Adam J.

2007-01-01

149

jessies author project  

NSDL National Science Digital Library

Students will discover authors by visiting websites. Then they will write a letter to an author. Choose five different authors and answer the questions below about each author. 1. Write the name of the author. 2. Where and when was this author born? 3. Name five books this author has written. 4. Tell one interesting thing you found on his or her website. 5. Tell one fact about ...

Meikle, Mrs.

2009-11-13

150

Efficacy and Safety of Clindamycin Phosphate 1.2% and Tretinoin 0.025% Gel for the Treatment of Acne and Acne-induced Post-inflammatory Hyperpigmentation in Patients with Skin of Color  

PubMed Central

Objective: To assess the efficacy and safety of a topical gel containing clindamycin 1.2% and tretinoin 0.025% for the treatment of acne and acne-induced postinflammatory hyperpigmentation (PIH) in darker skinned patients. Design: Randomized, double-blind, placebo-controlled study. Setting: Two United States clinical sites. Participants: Thirty-three patients 12 years of age or older with skin types IV to VI, mild-to-moderate facial acne, and PIH were enrolled. Measurements: Patients applied clindamycin phosphate/tretinoin gel or a nonmedicated vehicle each evening and a sun protection factor 30 sunscreen daily. Changes in skin erythema and hyperpigmentation were measured using a chromameter and photographic images. Efficacy was assessed using the Evaluators Global Acne Severity Scale, lesion counts, Post-inflammatory Hyperpigmentation Severity Scales and Patient’s Global Assessment Scale. Safety and tolerability were assessed by adverse event reports and a Safety Assessment Scale. Results: The mean (SD) baseline inflammatory lesion count was 11.9 (11.1) in clindamycin/tretinoin-treated patients, decreasing by 5.5 (6.56) after 12 weeks while the mean baseline inflammatory lesion count was 13.6 (11.15) in placebo-treated patients, decreasing by 4.1 (11.36) (p=0.05 for change from baseline, clindamycin/tretinoin vs. placebo). Clindamycin/tretinoin-treated patients generally demonstrated superior efficacy versus placebo treatment. The clindamycin/tretinoin topical gel was well tolerated, causing little or no irritation, although one patient withdrew due to periorbital edema of moderate severity possibly related to clindamycin/tretinoin gel. Conclusion: Although limited by small sample size, the results of this pilot study suggest clindamycin phosphate 1.2% and tretinoin 0.025% topical gel is a safe and effective option for treating mild-to-moderate acne in patients with skin of color.

Young, Cherie M.; Kindred, Chesahna; Taylor, Susan C.

2012-01-01

151

Efficacy and Safety of Clindamycin Phosphate 1.2% and Tretinoin 0.025% Gel for the Treatment of Acne and Acne-induced Post-inflammatory Hyperpigmentation in Patients with Skin of Color.  

PubMed

Objective: To assess the efficacy and safety of a topical gel containing clindamycin 1.2% and tretinoin 0.025% for the treatment of acne and acne-induced postinflammatory hyperpigmentation (PIH) in darker skinned patients. Design: Randomized, double-blind, placebo-controlled study. Setting: Two United States clinical sites. Participants: Thirty-three patients 12 years of age or older with skin types IV to VI, mild-to-moderate facial acne, and PIH were enrolled. Measurements: Patients applied clindamycin phosphate/tretinoin gel or a nonmedicated vehicle each evening and a sun protection factor 30 sunscreen daily. Changes in skin erythema and hyperpigmentation were measured using a chromameter and photographic images. Efficacy was assessed using the Evaluators Global Acne Severity Scale, lesion counts, Post-inflammatory Hyperpigmentation Severity Scales and Patient's Global Assessment Scale. Safety and tolerability were assessed by adverse event reports and a Safety Assessment Scale. Results: The mean (SD) baseline inflammatory lesion count was 11.9 (11.1) in clindamycin/tretinoin-treated patients, decreasing by 5.5 (6.56) after 12 weeks while the mean baseline inflammatory lesion count was 13.6 (11.15) in placebo-treated patients, decreasing by 4.1 (11.36) (p=0.05 for change from baseline, clindamycin/tretinoin vs. placebo). Clindamycin/tretinoin-treated patients generally demonstrated superior efficacy versus placebo treatment. The clindamycin/tretinoin topical gel was well tolerated, causing little or no irritation, although one patient withdrew due to periorbital edema of moderate severity possibly related to clindamycin/tretinoin gel. Conclusion: Although limited by small sample size, the results of this pilot study suggest clindamycin phosphate 1.2% and tretinoin 0.025% topical gel is a safe and effective option for treating mild-to-moderate acne in patients with skin of color. PMID:22798973

Callender, Valerie D; Young, Cherie M; Kindred, Chesahna; Taylor, Susan C

2012-07-01

152

Efficacy and safety of azelaic acid (AzA) gel 15% in the treatment of post-inflammatory hyperpigmentation and acne: a 16-week, baseline-controlled study.  

PubMed

Although there are few differences in the incidence and pathophysiology of acne across various races and ethnicities, there is some evidence that black patients may have larger sebaceous glands and increased sebum production. Of greater clinical relevance, patients with darker skin types are at increased risk for the development of post-inflammatory hyperpigmentation (PIH), which some find as or more troubling than acne itself. This common and bothersome sequelum of acne can be difficult to manage in this population. Topical azelaic acid gel is recognized to have anti-tyrosinase activity, suggesting it may be a suitable treatment option for mild-to-moderate acne with associated moderate-to-severe PIH. This pilot study demonstrates the efficacy of topical AzA gel 15% when applied twice daily for the reduction of both acne and PIH. J PMID:21637899

Kircik, Leon H

2011-06-01

153

Interactive Video Authoring Systems.  

ERIC Educational Resources Information Center

|Five articles describe the following microcomputer-based interactive video authoring aids: (1) IBM's Learning System/1; (2) Video Nova Authoring System; (3) IMSATT Corporation's expert-based authoring system; (4) the System for Authoring Microtraining (SAM); and (5) Omnicom's Content Expert Interviewer and Interactive Design and Authoring System.…

Taylor, Timothy D.; And Others

1987-01-01

154

Accelerator production of tritium authorization basis strategy  

Microsoft Academic Search

The Accelerator Production of Tritium (APT) project has proposed a strategy to develop the APT authorization basis and safety case based on DOE orders and fundamental requirements for safe operation. The strategy is viable regardless of whether the APT is regulated by DOE or by an external regulatory body. Currently the operation of Department of Energy (DOE) facilities is authorized

L. A. Miller; J. Edwards; S. Rose

1996-01-01

155

Authorize Compound Orders  

Cancer.gov

Home What's New Discovery Development Pathways Grants/Contracts Site Search Data Search NCI View Status / Authorize Orders Authorized representatives: Authorize Compound Orders If you ordered compounds from the DTP and wish to view the status of your

156

Authoring Considerations for Hypertext.  

ERIC Educational Resources Information Center

|Discusses some of the major aspects of authoring hypertext documents and databases as forms of interactive instruction. Highlights include knowledge structuring; root documents; authoring tools; screen formats; computer graphics; collaboration among authors; cognitive processes; and degree of learner control. (LRW)|

Kearsley, Greg

1988-01-01

157

Safety and efficacy of botox injection in alleviating post-operative pain and improving quality of life in lower extremity limb lengthening and deformity correction  

PubMed Central

Background Distraction osteogenesis is the standard treatment for the management of lower limb length discrepancy of more than 3 cm and bone loss secondary to congenital anomalies, trauma or infection. This technique consists of an osteotomy of the bone to be lengthened, application of an external fixator, followed by gradual and controlled distraction of the bone ends. Although limb lengthening using the Ilizarov distraction osteogenesis principle yields excellent results in most cases, the technique has numerous problems and is not well tolerated by many children. The objective of the current study is to determine if Botulinum Toxin A (BTX-A), which is known to possess both analgesic and paralytic actions, can be used to alleviate post-operative pain and improve the functional outcome of children undergoing distraction osteogenesis. Methods/Design The study design consists of a multi centre, randomized, double-blinded, placebo-controlled trial. Patients between ages 5–21 years requiring limb lengthening or deformity correction using distraction will be recruited from 6 different sites (Shriners Hospital for Children in Montreal, Honolulu, Philadelphia and Portland as well as DuPont Hospital for Children in Wilmington, Delaware and Hospital for Sick Children in Toronto, Ont). Approximately 150 subjects will be recruited over 2 years and will be randomized to either receive 10 units per Kg of BTX-A or normal saline (control group) intraoperatively following the surgery. Functional outcome effects will be assessed using pain scores, medication dosages, range of motion, flexibility, strength, mobility function and quality of life of the patient. IRB approval was obtained from all sites and adverse reactions will be monitored vigorously and reported to IRB, FDA and Health Canada. Discussion BTX-A injection has been widely used world wide with no major side effects reported. However, to the best of our knowledge, this is the first time BTX-A is being used under the context of limb lengthening and deformity correction. Trial Registration NCT00412035

Hamdy, Reggie C; Montpetit, Kathleen; Ruck-Gibis, Joanne; Thorstad, Kelly; Raney, Ellen; Aiona, Michael; Platt, Robert; Finley, Allen; Mackenzie, William; McCarthy, James; Narayanan, Unni

2007-01-01

158

The State of Authority.  

ERIC Educational Resources Information Center

|Describes the results of surveys that examined how academic libraries are employing authority control, the impact of AACR2 and online catalogs on the need for authority control, and the effect of OCLC cataloging on a university library catalog established without authority control for corporate or personal names. (62 references) (Author/CLB)|

Baer, Nadine L.; Johnson, Karl E.

1988-01-01

159

200 Area Deactivation Project Facilities Authorization Envelope Document  

SciTech Connect

Project facilities as required by HNF-PRO-2701, Authorization Envelope and Authorization Agreement. The Authorization Agreements (AA's) do not identify the specific set of environmental safety and health requirements that are applicable to the facility. Therefore, the facility Authorization Envelopes are defined here to identify the applicable requirements. This document identifies the authorization envelopes for the 200 Area Deactivation.

DODD, E.N.

2000-03-28

160

Author! Author! Making Kids Laugh: Jon Scieszka  

ERIC Educational Resources Information Center

|This article presents a brief biography of author Jon Scieszka, best known for his first published title, "The True Story of the Three Little Pigs!" which has become a modern classic. The publication of this creative and inventive title led to the numerous fractured fairy tales published since its release in 1989. His books have received numerous…

Brodie, Carolyn S.

2004-01-01

161

Author! Author! Seymour Simon: Science Writer Extraordinaire  

ERIC Educational Resources Information Center

|This column presents a brief biography of author Seymour Simon, whose topics for children's photo essays include icebergs, gorillas, thunderstorms, optical illusions, snakes, air, water, planets, airplanes, volcanoes, cars, the brain, bridges, bugs, crocodiles, skyscrapers, sharks, and paper airplanes. Though he is best known in the style and an…

Brodie, Carolyn S.

2005-01-01

162

Clinical Safety Assessment for Rotavirus Vaccines  

Center for Biologics Evaluation and Research (CBER)

Text VersionMonitoring Safety of Rotavirus Vaccines. ... Two post licensure safety signals: Increased risk posed by rotavirus vaccines to infants with SCID; ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

163

Safety of rFVIIa in hemodynamically unstable polytrauma patients with traumatic brain injury: post hoc analysis of 30 patients from a prospective, randomized, placebo-controlled, double-blind clinical trial  

PubMed Central

Background Trauma is a leading cause of mortality and morbidity, with traumatic brain injury (TBI) and uncontrolled hemorrhage responsible for the majority of these deaths. Recombinant activated factor VIIa (rFVIIa) is being investigated as an adjunctive hemostatic treatment for bleeding refractory to conventional replacement therapy in trauma patients. TBI is a common component of polytrauma injuries. However, the combination of TBI with polytrauma injuries is associated with specific risk factors and treatment modalities somewhat different from those of polytrauma without TBI. Although rFVIIa treatment may offer added potential benefit for patients with combined TBI and polytrauma, its safety in this population has not yet been assessed. We conducted a post hoc sub analysis of patients with TBI and severe blunt polytrauma enrolled into a prospective, international, double-blind, randomized, placebo-controlled study. Methods A post hoc analysis of study data was performed for 143 patients with severe blunt trauma enrolled in a prospective, randomized, placebo-controlled study, evaluating the safety and efficacy of intravenous rFVIIa (200 + 100 + 100 ?g/kg) or placebo, to identify patients with a computed tomography (CT) diagnosis of TBI. The incidences of ventilator-free days, intensive care unit-free days, and thromboembolic, serious, and adverse events within the 30-day study period were assessed in this cohort. Results Thirty polytrauma patients (placebo, n = 13; rFVIIa, n = 17) were identified as having TBI on CT. No significant differences in rates of mortality (placebo, n = 6, 46%, 90% confidence interval (CI): 22% to 71%; rFVIIa, n = 5, 29%, 90% CI: 12% to 56%; P = 0.19), in median numbers of intensive care unit-free days (placebo = 0, rFVIIa = 3; P = 0.26) or ventilator-free days (placebo = 0, rFVIIa = 10; P = 0.19), or in rates of thromboembolic adverse events (placebo, 15%, 90% CI: 3% to 51%; rFVIIa, 0%, 90% CI: 0% to 53%; P = 0.18) or serious adverse events (placebo, 92%, 90% CI: 68% to 98%; rFVIIa, 82%, 90% CI: 60% to 92%; P = 0.61) were observed between treatment groups. Conclusion The use of a total dose of 400 (200 + 100 + 100) ?g/kg rFVIIa in this group of hemodynamically unstable polytrauma patients with TBI was not associated with an increased risk of mortality or with thromboembolic or adverse events.

Kluger, Yoram; Riou, Bruno; Rossaint, Rolf; Rizoli, Sandro B; Boffard, Kenneth David; Choong, Philip Iau Tsau; Warren, Brian; Tillinger, Michael

2007-01-01

164

Toddler drowning prevention: Teaching parents about water safety in conjunction with their child's in-water lessons  

Microsoft Academic Search

The primary objective of the study was to develop a parent education programme that addressed parental misconceptions of toddler water safety previously identified by the authors. Parents (n = 106) of 2 – 4-year-old toddlers enrolled in swim school lessons completed a self-directed questionnaire before and after a 10-week poolside water safety programme. Differences in pre- and post-programme knowledge and beliefs were measured by

K. Moran

2006-01-01

165

20 CFR 725.706 - Authorization to provide medical services.  

Code of Federal Regulations, 2013 CFR

...2013-04-01 false Authorization to provide medical services. 725.706 Section 725...MINE SAFETY AND HEALTH ACT, AS AMENDED Medical Benefits and Vocational Rehabilitation § 725.706 Authorization to provide medical services. (a) Except as...

2013-04-01

166

36 CFR 1004.3 - Authorized emergency vehicles.  

Code of Federal Regulations, 2011 CFR

...2011-07-01 false Authorized emergency vehicles. 1004.3 Section 1004.3 Parks...and Public Property PRESIDIO TRUST VEHICLES AND TRAFFIC SAFETY § 1004.3 Authorized emergency vehicles. (a) The operator of an...

2011-07-01

167

36 CFR 1004.3 - Authorized emergency vehicles.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 false Authorized emergency vehicles. 1004.3 Section 1004.3 Parks...and Public Property PRESIDIO TRUST VEHICLES AND TRAFFIC SAFETY § 1004.3 Authorized emergency vehicles. (a) The operator of an...

2012-07-01

168

78 FR 52457 - Transfers of Operating Authority Registration  

Federal Register 2010, 2011, 2012, 2013

...Safety Administration 49 CFR Part 365 Transfers of Operating Authority Registration AGENCY...and legal interpretation for recording transfers of operating authority registration by...of 49 CFR part 365, subpart D, ``Transfer of Operating Rights under 49...

2013-08-23

169

33 CFR 96.430 - How does an organization submit a request to be authorized?  

Code of Federal Regulations, 2013 CFR

...RULES FOR THE SAFE OPERATION OF VESSELS AND SAFETY MANAGEMENT SYSTEMS Authorization...CG-521), Office of Design and Engineering...this part for safety management auditing and certification...C9001 for safety management auditing and...

2013-07-01

170

And Speaking of Authority...  

ERIC Educational Resources Information Center

|Over breakfast at the American Library Association (ALA) Annual Conference, this author was asked, "What is authority? What does one know about the ways in which he/she determines credibility? Whom do you trust?" In this article, the author focuses on these questions in terms of administrators who have control over libraries. She provides a…

Williams, Connie

2010-01-01

171

National Transportation Safety Board Railroad Accident Report: Derailment of Washington Metropolitan Area Transit Authority Train near the Mt. Vernon Square Station, Washington, D.C. on January 7, 2007.  

National Technical Information Service (NTIS)

On January 7, 2007, about 3:45 p.m. Eastern Standard Time, northbound Washington Metropolitan Area Transit Authority Metrorail train 504 derailed one car as the train traversed a crossover from track 2 to track 1. The accident occurred in an underground t...

2007-01-01

172

Efficacy of current EC meat inspection procedures and some proposed revisions with respect to microbiological safety: a critical review  

Microsoft Academic Search

This paper presents an evaluation of the current EC meat inspection procedures, and some of their proposed revisions, in relation to their efficacy in assuring the microbiological safety and quality of meat, and the difficulties for health authorities and industry in providing such an assurance. It is concluded that neither the current nor the proposed revisions of ante and post

BR Berends; JM Snijders; JG van Logtestijn

1993-01-01

173

42 CFR 3.544 - Post hearing briefs.  

Code of Federal Regulations, 2012 CFR

...Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS PATIENT SAFETY ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT Enforcement Program § 3.544 Post hearing briefs. The ALJ may require the...

2012-10-01

174

42 CFR 3.544 - Post hearing briefs.  

Code of Federal Regulations, 2011 CFR

...Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS PATIENT SAFETY ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT Enforcement Program § 3.544 Post hearing briefs. The ALJ may require the...

2011-10-01

175

Lightning Safety  

MedlinePLUS

Lightning Safety: When Thunder Roars, Go Indoors! What's New? September 2013 Lightning Safety Blog What You Need to Know: Tips for Safety NWS Lightning Safety Awareness Message 2013 Lightning Deaths in 2013 ...

176

Author names and affiliations  

Microsoft Academic Search

Road rage is a topic that receives consistent attention in both the road safety literature and media. Before Australian research can address the underlying factors associated with road rage, there is a need for a valid instrument appropriate for use in this context. The present program of research consisted of two studies. Study 1 used a university sample to adjust

Nerida L. Lealab; Nancy A. Pachana

177

Authoring tool evaluation  

SciTech Connect

This paper discusses and evaluates a number of authoring tools currently on the market. The tools evaluated are Visix Galaxy, NeuronData Open Interface Elements, Sybase Gain Momentum, XVT Power++, Aimtech IconAuthor, Liant C++/Views, and Inmark Technology zApp. Also discussed is the LIST project and how this evaluation is being used to fit an authoring tool to the project.

Wilson, A.L.; Klenk, K.S.; Coday, A.C.; McGee, J.P.; Rivenburgh, R.R.; Gonzales, D.M.; Mniszewski, S.M.

1994-09-15

178

Collaborative Courseware Authoring Support  

Microsoft Academic Search

We refined our knowledge classification and indexing approach applied in our previously developed system AIMS (Agent-based Information Management System) by introducing ontology-oriented support for collaborative courseware authoring. In order to provide a basis for formal semantics and reasoning in performing generic authoring tasks, we add ontology-based layers in the courseware authoring architecture. Ontological structuring also opens the way for cooperative

Darina Dicheva; Lora Aroyo; Alexandra Cristea

2002-01-01

179

Twentieth-century Authors  

NSDL National Science Digital Library

College and Research Library News has posted this new annotated directory to aid students and researchers working with English literature of the twentieth century. This site focuses on major English-language writers, offering mainly "biographical and bibliographic information, with some information on literary criticism."

180

Parental authority questionnaire.  

PubMed

A questionnaire was developed for the purpose of measuring Baumrind's (1971) permissive, authoritarian, and authoritative parental authority prototypes. It consists of 30 items per parent and yields permissive, authoritarian, and authoritative scores for both the mother and the father; each of these scores is derived from the phenomenological appraisals of the parents' authority by their son or daughter. The results of several studies have supported the Parental Authority Questionnaire as a psychometrically sound and valid measure of Baumrind's parental authority prototypes, and they have suggested that this questionnaire has considerable potential as a valuable tool in the investigation of correlates of parental permissiveness, authoritarianism, and authoritativeness. PMID:16370893

Buri, J R

1991-08-01

181

Surveillance: Post Drug-Approval Activities  

Center for Drug Evaluation (CDER)

... Surveillance: Post Drug-Approval Activities. A vital part of CDER's mission is to monitor the safety and effectiveness of drugs that are currently ... More results from www.fda.gov/drugs/guidancecomplianceregulatoryinformation/surveillance

182

The Voice of Authority  

ERIC Educational Resources Information Center

In the last part of 2011, conversations swirled around the Internet and print about the assault on museum authority. The Marcus Institute for Digital Education in the Arts (MIDEA) summarized some of the discussion in their blog entry "The Participatory Museum and a New Authority." Other sites joined in the discussion, for example, the Museum Geek…

Wetterlund, Kris

2012-01-01

183

Question the Author  

NSDL National Science Digital Library

This web page describes the comprehension strategy of Question the Author (QtA), a strategy in which students pose questions while reading nonfiction text. Students pose questions about the author's purpose in including certain phrases or forms of information while reading. Sample questions are provided in a three-step instructional sequence. References are included.

2012-01-01

184

Informal Authority in Organizations  

Microsoft Academic Search

We assert that decision rights in organizations are not contractible: the boss can always overturn a subordinate's decision, so formal authority resides only at the top. Although decision rights cannot be formally delegated, they might be informally delegated through self-enforcing relational contracts. We examine the feasibility of informal authority in two informational environments. We show that different information structures produce

George Baker; Robert Gibbons; Kevin J Murphy

1999-01-01

185

Central Authority and Order  

Microsoft Academic Search

Strong central authorities are able to effectively manage costly defection, but are unable to adequately address lesser conflicts because of limits to their ability to monitor and enforce. We argue, counterintuitively, that these limitations build coop- eration and trust among subordinates:the limitations contribute to the production of order. First, limits to authority leave space for locally informed decentralized enforce- ment.

Emily Erikson; Joseph M. Parent

2007-01-01

186

Authoring of Adaptive Hypermedia  

Microsoft Academic Search

This paper briefly describes the important topic of Authoring of Adaptive Hypermedia that is central to this Special Issue especially from the point of view of education, as well as the papers selected and the reason for this selection. The papers are based on selected, invited papers of the second Workshop on Authoring of Adaptive and Adaptable Educational Hypermedia at

Alexandra Cristea

2005-01-01

187

78 FR 12065 - Patient Safety Organizations: Delisting for Cause for Independent Data Safety Monitoring, Inc.  

Federal Register 2010, 2011, 2012, 2013

...Healthcare Research and Quality Patient Safety Organizations: Delisting for...to correct a deficiency. The Patient Safety and Quality Improvement Act of 2005 (Patient Safety Act) authorizes the listing...

2013-02-21

188

41 CFR 302-9.206 - What should I do if there is no port or terminal at my authorized point of origin or authorized...  

Code of Federal Regulations, 2011 CFR

...authorized point of origin or authorized destination when I transport a POV from my post of duty? 302-9.206 Section 302-9...authorized point of origin or authorized destination when I transport a POV from my post of duty? If there is no port or...

2011-07-01

189

41 CFR 302-9.206 - What should I do if there is no port or terminal at my authorized point of origin or authorized...  

Code of Federal Regulations, 2012 CFR

...authorized point of origin or authorized destination when I transport a POV from my post of duty? 302-9.206 Section 302-9...authorized point of origin or authorized destination when I transport a POV from my post of duty? If there is no port or...

2012-07-01

190

Young Adult Authors on the Internet.  

ERIC Educational Resources Information Center

|Discusses publishing on the Internet by young authors. Describes "fan-fiction" Web sites where fans write passages that link to characters in popular books, television shows, or movies; fan-fiction inspired by the Disney film "Newsies"; posting short stories on Web pages; poetry, book reviews, and other publications; the attraction of the…

Flench, Chris Ebert

1999-01-01

191

Authorization basis requirements comparison report  

SciTech Connect

The TWRS Authorization Basis (AB) consists of a set of documents identified by TWRS management with the concurrence of DOE-RL. Upon implementation of the TWRS Basis for Interim Operation (BIO) and Technical Safety Requirements (TSRs), the AB list will be revised to include the BIO and TSRs. Some documents that currently form part of the AB will be removed from the list. This SD identifies each - requirement from those documents, and recommends a disposition for each to ensure that necessary requirements are retained when the AB is revised to incorporate the BIO and TSRs. This SD also identifies documents that will remain part of the AB after the BIO and TSRs are implemented. This document does not change the AB, but provides guidance for the preparation of change documentation.

Brantley, W.M.

1997-08-18

192

TV Station Authorization Report.  

National Technical Information Service (NTIS)

A list of cable television stations authorized to broadcast television station programs identified by call letters and location is given. This includes the community name, the cable television operator's legal name, and the number of subscribers for each ...

1979-01-01

193

Corporate Author Headings.  

National Technical Information Service (NTIS)

This list of corporate author headings represents a coordinated effort of Government agencies to facilitate the exchange of scientific and technical cataloging information. Of particular value are the extensive cross references which indicate variant name...

1970-01-01

194

Today's Authors, Tomorrow's Scientists  

NSDL National Science Digital Library

Although not all teachers can invite scientists into classrooms on a regular basis, they can invite them into their students' worlds through literature. Here the author shares how she used the nonfiction selection, Science to the Rescue (Markle 1

Porter, Diana

2009-10-01

195

FDA Drug Safety Communication: Safety review of post ...  

Center for Drug Evaluation (CDER)

... Pradaxa is a blood thinning (anticoagulant) medication used to reduce the risk of stroke in patients with non-valvular atrial fibrillation (AF), the most ... More results from www.fda.gov/drugs/drugsafety

196

Authoring systems reassessed  

Microsoft Academic Search

A study of authoring system technology was done to update a previous study done in 1985. While the earlier study focused on\\u000a software selection methods, the current one emphasizes trends in authoring tool characteristics, vendor approaches to the\\u000a market-place, and evaluation methods. It also raises questions about some of the often tacit assumptions underlying the technology's\\u000a development and use.

Craig Locatis; Eldon Ullmer; Victor Carr; Richard Banvard; Quang Le; Raulie Lo; Matthew Williamson

1992-01-01

197

Commentary: Obscured Authority  

Microsoft Academic Search

\\u000a In the case discussion of Heineken and the promotion girls in Cambodia we address the question to what extent Heineken is\\u000a responsible for the well-being of promotion girls in Cambodia. Heineken’s authority in Cambodia is obscured: at best it has\\u000a a shared authority, in this case with Heineken’s Asian partners, the Cambodian government and the establishment owners. In\\u000a examining Heineken’s

Raoul Wirtz; Edgar Karssing; Gemma Crijns

2011-01-01

198

Authors and publication practices  

Microsoft Academic Search

Although authors are usually considered to be the main perpetrators of research and publication misconduct, any person involved\\u000a in the process has the potential to offend. Editors may breach ethical standards particularly with respect to conflicts of\\u000a interest. In the same way that authors are now required to declare competing interests, notably commercial affiliations, financial\\u000a interests and personal connections, so

Michael J. G. Farthing

2006-01-01

199

Post Clamp.  

National Technical Information Service (NTIS)

A pair of spaced collars are mounted at right angles on a clamp body by retaining rings which enable the collars to rotate with respect to the clamp body. Mounting posts extend through aligned holes in the collars and clamp body. Each collar can be clampe...

J. K. Ramsey E. M. Meyn

1989-01-01

200

30 CFR 57.6502 - Safety fuse.  

Code of Federal Regulations, 2010 CFR

...2009-07-01 2009-07-01 false Safety fuse. 57.6502 Section 57.6502 Mineral...Blasting-Surface and Underground § 57.6502 Safety fuse. (a) The burning rate of each spool of safety fuse to be used shall be measured, posted...

2009-07-01

201

30 CFR 56.6502 - Safety fuse.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Safety fuse. 56.6502 Section 56.6502 Mineral...Nonelectric Blasting § 56.6502 Safety fuse. (a) The burning rate of each spool of safety fuse to be used shall be measured, posted...

2010-07-01

202

30 CFR 56.6502 - Safety fuse.  

Code of Federal Regulations, 2010 CFR

...2009-07-01 2009-07-01 false Safety fuse. 56.6502 Section 56.6502 Mineral...Nonelectric Blasting § 56.6502 Safety fuse. (a) The burning rate of each spool of safety fuse to be used shall be measured, posted...

2009-07-01

203

ARPA Authoring System.  

National Technical Information Service (NTIS)

The work during this reporting period has concentrated on preparations for a full-scale test of the ARPA Authoring System in FY 78. A five-stage procedure has been developed for management of task-oriented lesson development in the on-the-job environment....

W. P. Harris

1977-01-01

204

Authoring with Video  

ERIC Educational Resources Information Center

|Teachers are hungry for strategies that will motivate their students to engage in reading and writing. One promising method is the Authoring With Video (AWV) approach, which encourages teachers to use captioning software and digital video in writing assignments. AWV builds on students' fascination with television and video but removes the audio…

Strassman, Barbara K.; O'Connell, Trisha

2007-01-01

205

Author Identification Systems  

ERIC Educational Resources Information Center

|Many efforts are currently underway to disambiguate author names and assign unique identification numbers so that publications by a given scholar can be reliably grouped together. This paper reviews a number of operational and in-development services. Some systems like ResearcherId.Com depend on self-registration and self-identification of a…

Wagner, A. Ben

2009-01-01

206

FDA Authority Over Cosmetics  

MedlinePLUS

FDA Authority Over Cosmetics March 3, 2005; updated August 3, 2013 In the United States, federal laws are enacted by Congress. In order ... license to operate? What kinds of products are “cosmetics” under the law? The FD&C Act defines ...

207

Authoring adaptive multimedia services  

Microsoft Academic Search

In this paper, we describe new content authoring issues related to mobility and cross-platform multimedia systems. We present the novel architecture for Content Provider Interface (CPI), which provides the necessary tools for creation and delivery of mobile multimedia services across heterogeneous environments. CPI is a fully implemented system and set of tools for creating and updating new multimedia services delivered

Tuomas T. T. Polvi; Antti T. Koivisto; Jaakko J. Sauvola

2001-01-01

208

Authors on Film.  

ERIC Educational Resources Information Center

|Different authors' attitudes toward film are revealed through five different sections of this book: (1) articles, essays, and reviews pertaining to the silent cinema and the transition to sound; (2) general statements on the film medium or filmmakers and their messages; (3) essays dealing with the problems, involvements, and reflections of the…

Geduld, Harry M., Ed.

209

Reengineering Name Authority Control.  

ERIC Educational Resources Information Center

|Describes a model for the standardization of names in bibliographic databases. Discusses a prototype that was developed to demonstrate feasibility of the model, and investigates the impact of implementing the model. Findings suggested that the new model will revolutionize name authority control and that the prototype verifies the technical…

Snyman, M. M. M.; Van Rensburg, M. Jansen

1999-01-01

210

Case Authors Directory  

NSDL National Science Digital Library

One of our goals is to build a community of case study teachers in science and engineering. Our directory lists all our case authors as well as case method practitioners (many of them trained by us) teaching in high school, community college, and university settings.

2010-01-01

211

FFTF Authorization Agreement  

SciTech Connect

The purpose of the Authorization Agreement is to serve as a mechanism whereby the U.S. Department of Energy, Richland Operations Office (RL) and Fluor Hanford (FH) jointly clarify and agree to key conditions for conducting work safely and efficiently.

DAUTEL, W.A.

2000-02-25

212

Comparing American Authors  

NSDL National Science Digital Library

How are Edgar Allen Poe and Mark Twain similar? How similar are Edgar Allen Poe and Mark Twain really? They are two of the greatest authors from the 19th Century but they appear to be very different. Read section 7 here of Mark Twain s Style and then read this excerpt from Twain's Tom Sawyer to fully understand his writing style. What things ...

Hall, Ms.

2010-03-24

213

10 CFR 76.81 - Authorized use of radioactive material.  

Code of Federal Regulations, 2013 CFR

...2013-01-01 false Authorized use of radioactive material. 76.81 Section 76...Safety § 76.81 Authorized use of radioactive material. Unless otherwise authorized...shall confine its possession and use of radioactive material to the locations...

2013-01-01

214

The safety envelope: managing the safety culture  

Microsoft Academic Search

The commercial nuclear industry, the US Naval Nuclear Propulsion Program, and the DOE nuclear complex have used various models to operate and manage complex nuclear facilities in a safe manner. These models have focused primarily on operating parameters and design control. Using the idea of a safety envelope, the authors describe a new model that depicts the interrelationship of these

E. B. Blackwood; W. E. Carnes; M. H. Sturdivant

1992-01-01

215

The Author's Report  

NASA Astrophysics Data System (ADS)

The referee's report is a standard rite of passage for an author of articles in The Physics Teacher. Will the referee (and the editor) agree with the basic premise and the details of your carefully thought-out article? I have faced this moment of truth many times; the majority of them were during the editorship of Cliff Swartz. These reminiscences are as much about the journal as Cliff, for, to many of us, the two seemed inseparable.

Greenslade, Thomas B.

2011-01-01

216

47 CFR 0.314 - Additional authority delegated.  

Code of Federal Regulations, 2012 CFR

...authority for operation without monitors, plate ammeter, plate volmeter, base current meter, common point meter, and transmission line meter from FM and television stations. (b)(1) Extend the Communications Act Safety Radiotelephony...

2012-10-01

217

48 CFR 50.102-1 - Delegation of authority.  

Code of Federal Regulations, 2012 CFR

...CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 50.102-1 Delegation...amount, authority to indemnify against unusually hazardous or nuclear risks, including extension of such indemnification to...

2012-10-01

218

48 CFR 50.102-1 - Delegation of authority.  

Code of Federal Regulations, 2011 CFR

...CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 50.102-1 Delegation...amount, authority to indemnify against unusually hazardous or nuclear risks, including extension of such indemnification to...

2011-10-01

219

50 CFR 38.4 - Authorized functions, powers, and duties.  

Code of Federal Regulations, 2010 CFR

...NATIONAL WILDLIFE REFUGE SYSTEM MIDWAY ATOLL NATIONAL WILDLIFE REFUGE Executive Authority...Lawful removal of person from the Midway Atoll National Wildlife Refuge for cause; ...safety of persons and property on Midway Atoll National Wildlife Refuge; and...

2009-10-01

220

47 CFR 101.139 - Authorization of transmitters.  

Code of Federal Regulations, 2012 CFR

...CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Technical Standards § 101.139 Authorization...operational fixed and common carrier fixed point-to-point microwave and point-to-multipoint services under this part...

2012-10-01

221

47 CFR 101.139 - Authorization of transmitters.  

Code of Federal Regulations, 2011 CFR

...CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Technical Standards § 101.139 Authorization...operational fixed and common carrier fixed point-to-point microwave and point-to-multipoint services under this part...

2011-10-01

222

[Activity and safety of fenspiride in bronchial hyperexudation (author's transl)].  

PubMed

This clinical trial of fenspiride (injectable and sustained-release 80 mg tablet) was carried out on patients selected because their bronchopathy was of a hypersecretory type. Interesting results were observed in 20 out of 37 cases, but they were often delayed. This group of patients included a high proportion of patients with major hypersecretion; the efficacy of fenspiride is often evident, (in 8 out of 11 cases) but it is unpredictable individually. It can be concluded from this trial that a long term treatment with fenspiride, well tolerated, can usefully be tried in patients with predominant signs of bronchial hyperexudation. PMID:42144

de Labarthe, B; Gosset, X; Dourmap, C; Delaval, P; Le Rest, R

223

49 CFR 218.61 - Authority to deactivate safety devices.  

Code of Federal Regulations, 2012 CFR

...a train movement under part 232 of this chapter: (3) The locomotive is dead-in-tow; or (4) The locomotive is a mid-train slave unit being controlled by radio from a remote location. (c) If a locomotive is equipped with a device...

2012-10-01

224

49 CFR 218.61 - Authority to deactivate safety devices.  

Code of Federal Regulations, 2011 CFR

...a train movement under part 232 of this chapter: (3) The locomotive is dead-in-tow; or (4) The locomotive is a mid-train slave unit being controlled by radio from a remote location. (c) If a locomotive is equipped with a device...

2011-10-01

225

Radiation safety systems at the NSLS  

SciTech Connect

This report describes design principles that were used to establish the radiation safety systems at the National Synchrotron Light Source. The author described existing safety systems and the history of partial system failures. 1 fig. (TEM)

Dickinson, T.

1987-04-01

226

[Bisalbuminemia (author's transl)].  

PubMed

After a review of first two causes of bisalbuminemia: genetic mutation and overdosage during antibiotherapy with beta-lactamines, the authors underline the importance of searching for a bisalbuminemia during the course of pancreatic disease or when confronted with a serous collection, particularly an ascite of undetermined origin. Effectively, the finding of a bisalbuminemia in these two circumstances, after having eliminated the first two etiologies, permits the confirmation of the diagnostic of a pancreatic fistula. This diagnostic should imply exploratory surgery, even without other confirmation, and a per-op. wirsungography if the fistula is not visible macroscopically. The surgical correction of the fistula cures the patient and the bisalbuminemia disappears in several hours. PMID:7114524

Albaret, S; Cavellat, J F; Jeudy, C; Delhumeau, A; Cavellat, M

1981-01-01

227

Electronic authoring tools  

SciTech Connect

More than a decade ago, word processing software revolutionized the way documents were prepared, and productivity was increased. But the editing and formatting capabilities of most word processors did very little to prevent errors in spelling, typing, grammar, diction, style, or organization from slipping through to the final documents. In the past few years, the number of software tools that aid the author has increased substantially. They now vary in scope from simple spelling checkers to sophisticated diction analyzers and idea processors. Moreover, writing-aid-software described in this report is now available for many types of computing systems, including personal computers, scientific workstations, and mainframes. The various pieces of software can be used in interactive or non-interactive (batch) modes.

Hurford, J.M.

1987-01-01

228

A question of authority  

SciTech Connect

A Question of Authority. This article deals with a certain scenario and several reviewers are to give their opinion. This one is in regards to - Suspending an IACUC approved animal use activity is about the last thing a research institution wants to do. Consider the predicament that the Great Eastern University IACUC faced when Dr. Janet Jenkins, the Attending Veterinarian, suspended all animal use activity on an approved protocol of Dr. Roy Maslo. Jenkins had the IACUCs authority to temporarily suspend a protocol, subject to review by a quorum of the full committee. She alleged that Maslo used mice from his breeding colony, not purchased rats, to begin a new study. Jenkins saw Maslos technicians bringing mouse cages to a procedure room and setting up for a minor survival surgery. She asked them to wait until she clarified things as she felt confident that the protocol called for rats. She called Maslo and asked him if the study had been approved for mice, to which he responded affirmatively. Still not feeling quite assured, she went to her office, reviewed the protocol, and found only rat studies described. She also called the IACUC office to see if there were any approved amendments which she may not have received, and was told that there were none. By the time she returned, one procedure was completed. Understandably upset, she informed the technicians and Maslo that any further activity on the protocol was suspended until the issue was resolved. Jenkins informed the IACUC chairman who in turned called an emergency meeting of the committee.

Morgan, Earl W. (BATTELLE (PACIFIC NW LAB))

2003-10-15

229

Comparison of commercial/industry and nuclear weapons safety concepts.  

National Technical Information Service (NTIS)

In this paper the authors identify factors which influence the safety philosophy used in the US commercial/industrial sector and compare them against those factors which influence nuclear weapons safety. Commercial/industrial safety is guided by private a...

R. R. Bennett D. A. Summers

1996-01-01

230

30 CFR 57.12022 - Authorized persons at major electrical installations.  

Code of Federal Regulations, 2013 CFR

...LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Electricity Surface and Underground § 57.12022 Authorized persons at major electrical installations. Areas containing...

2013-07-01

231

30 CFR 56.12022 - Authorized persons at major electrical installations.  

Code of Federal Regulations, 2013 CFR

...DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Electricity § 56.12022 Authorized persons at major electrical installations. Areas containing major electrical...

2013-07-01

232

Material Safety Data Sheets  

NSDL National Science Digital Library

The Loctite corporation, which manufactures sealants, adhesives and coatings, has recently posted online a searchable database of materials safety information pages. Users enter keywords to retrieve listings of composition, physical properties, toxicity, and stability of compounds. Recommendations for storage and disposal, emergency first aid, and fire management are also provided. The database features Loctite products exclusively, but it does contain substantial listings that researchers and workers handling chemicals might need.

2005-12-13

233

Authoring adaptive multimedia services  

NASA Astrophysics Data System (ADS)

In this paper, we describe new content authoring issues related to mobility and cross-platform multimedia systems. We present the novel architecture for Content Provider Interface (CPI), which provides the necessary tools for creation and delivery of mobile multimedia services across heterogeneous environments. CPI is a fully implemented system and set of tools for creating and updating new multimedia services delivered via a mobile adaptive multimedia service platform called Princess. CPI is based on an object-oriented database for editing and storing media objects, which are interpreted to service catalogs and presentations. Additionally, CPI is capable of creating rich notifications to the system to dynamically report content updates and allows users to create and use templates to establish new media objects, combine databases and preview presentations outside the service platform. The proposed approach addresses the requirements and difficulties of the cross-platform multimedia systems by integrating data management, service logic and modular service/presentation design together in a unique way with dynamic content updates and notification features, as well as user group management.

Polvi, Tuomas T.; Koivisto, Antti T.; Sauvola, Jaakko J.

2001-11-01

234

Patient safety in clinical research articles.  

PubMed

Patient safety has remained one of the most important priorities over the past decade, particularly in hospital settings. Implementation of patient safety measures has focused not only on reducing medication and surgical errors but also on the development of a culture of safety, including enhanced communication among all healthcare stakeholders. Academic medicine may further contribute to the culture of safety if all relevant clinical article submissions address patient safety. In order to improve communication between the authors of clinical research articles and practicing physicians, we propose that each clinical research article may be accompanied by a clear statement from the authors regarding practice implications and patient safety. PMID:23910178

Vintzileos, Anthony M; Finamore, Peter S; Sicuranza, Genevieve B; Ananth, Cande V

2013-08-01

235

324 Building safety basis criteria document  

SciTech Connect

The Safety Basis Criteria document describes the proposed format, content, and schedule for the preparation of an updated Safety Analysis Report (SAR) and Operational Safety Requirements document (OSR) for the 324 Building. These updated safety authorization basis documents are intended to cover stabilization and deactivation activities that will prepare the facility for turnover to the Environmental Restoration Contractor for final decommissioning. The purpose of this document is to establish the specific set of criteria needed for technical upgrades to the 324 Facility Safety Authorization Basis, as required by Project Hanford Procedure HNF-PRO-705, Safety Basis Planning, Documentation, Review, and Approval.

STEFFEN, J.M.

1999-06-02

236

Finding interesting posts in Twitter based on retweet graph analysis  

Microsoft Academic Search

Millions of posts are being generated in real-time by users in social networking services, such as Twitter. However, a considerable number of those posts are mundane posts that are of interest to the authors and possibly their friends only. This paper investigates the problem of automatically discovering valuable posts that may be of potential interest to a wider audience. Specifically,

Min-Chul Yang; Jung-Tae Lee; Seung-Wook Lee; Hae-Chang Rim

2012-01-01

237

Patient Safety  

MedlinePLUS

Patient safety is one of the nation's most pressing health care challenges. A 1999 report by the Institute ... each year as the result of lapses in patient safety. There are things you can do to help ...

238

Safety Alert  

Center for Biologics Evaluation and Research (CBER)

Text VersionPage 1. Safety Alert If you are being treated for asthma, taking a long-acting beta agonist (LABA) ... Page 2. Early Safety Alert ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

239

Safety Activities  

ERIC Educational Resources Information Center

|This article presents 10 safety activities for children. Among others, car and bus safety activities helps children develop social and language skills as they simulate riding safely in a car or bus.|

Early Childhood Today, 2005

2005-01-01

240

Hand Safety  

MedlinePLUS

... Hand Safety Currently selected Hand Surgeons Agree: Leave Fireworks to the Professionals Keep Your Hands Safe: Follow ... Hand Safety Currently selected Hand Surgeons Agree: Leave Fireworks to the Professionals Keep Your Hands Safe: Follow ...

241

Safety Rules  

NSDL National Science Digital Library

Safety is an important part of a science lesson or activity. This safety material is part of a series of hands-on science activities designed to arouse student interest. Sixteen rules reinforce common safety concerns for science classrooms. Among the safety rules are the recommendations that teachers practice demonstrations before presenting them, make proper eyewear and shields available, use customary disposal techniques, and possess a thorough knowledge of the chemical reactions being used. Copyright 2005 Eisenhower National Clearinghouse

Mid-continent Research for Education and Learning (McREL); Jacobs, Steve

2004-01-01

242

47 CFR 80.311 - Authority for distress transmission.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 2011-10-01 false Authority for distress transmission. 80.311 Section 80.311 Telecommunication FEDERAL...and Safety Procedures § 80.311 Authority for distress transmission. A mobile station in distress may use any means at...

2011-10-01

243

47 CFR 80.311 - Authority for distress transmission.  

Code of Federal Regulations, 2012 CFR

...2012-10-01 2012-10-01 false Authority for distress transmission. 80.311 Section 80.311 Telecommunication FEDERAL...and Safety Procedures § 80.311 Authority for distress transmission. A mobile station in distress may use any means at...

2012-10-01

244

29 CFR 1975.2 - Basis of authority.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Basis of authority. 1975.2 Section 1975.2 Labor Regulations Relating to Labor (Continued...WILLIAMS-STEIGER OCCUPATIONAL SAFETY AND HEALTH ACT OF 1970 § 1975.2 Basis of authority. The power of...

2010-07-01

245

Systematic Model-Based Safety Assessment via Probabilistic Model Checking  

Microsoft Academic Search

Safety assessment is a well-established process for assuring the safety and reliability of critical (aeronautical) systems. It uses probabilistic (quantitative) analysis to provide precise measures about the safety requirements of a system. Traditionally, quantitative safety assessment uses fault-tree analysis, but certification authorities also allow the use of Markov models. In this paper we propose a strategy for quantitative safety assessment

Adriano Gomes; Alexandre Mota; Augusto Sampaio; Felipe Ferri; Julio Buzzi

2010-01-01

246

Diversity and safety hazards of bacteria involved in meat fermentations  

Microsoft Academic Search

Food safety is a major concern for consumers and a major issue for industry which has become aware of the importance of the starter safety assessment. In the European Union, the Food Safety Authority has introduced the Qualified Presumption of Safety (QPS) approach for safety assessment of microorganisms throughout the food chain. This assessment relies on: taxonomy, familiarity, pathogenicity and

Régine Talon; Sabine Leroy

2011-01-01

247

LEMONADE: A Flexible Authoring Tool for Integrated Mobile Learning Scenarios  

Microsoft Academic Search

Most of the existing mobile learning environments for supporting field trip activities are limited to specific domains or contents and do not support authoring. We present a framework for planning and conducting field trips with mobile devices called LEMONADE, which provides full cycle support for authoring and conducting field trips, as well as for post-trip reporting and reflection activities. LEMONADE

Adam Giemza; Lars Bollen; Peter Seydel; André Overhagen; H. Ulrich Hoppe

2010-01-01

248

Monitoring the Safety of Clinical Trials  

MedlinePLUS

... Statistics Research & Funding News About NCI Learn About Clinical Trials Posted: 02/06/2001 Reviewed: 05/01/2006 ... Trials States Requiring Coverage Monitoring the Safety of Clinical Trials If you are thinking about participating in a ...

249

FDA Drug Safety Communication: Updated information about ...  

Center for Drug Evaluation (CDER)

... is in follow-up to the FDA Drug Safety Communication posted on 7 ... in patients receiving other psychiatric drugs with lesser degrees of serotonergic ... More results from www.fda.gov/drugs/drugsafety

250

Hanford site post NPH building inspection plan  

SciTech Connect

This plan establishes consistent post-NPH building inspection procedures and defines a procedure for prioritization of buildings for inspection to ensure the safety of facilities prior to reentry. Qualification of systems for restart of operation is not included. This plan takes advantage, where possible, of existing national procedures for post-NPH inspection of buildings, of existing structural design and evaluation documentation of Hanford facilities, and current and proposed seismic instrumentation located throughout the Hanford site. A list of buildings, prioritized according to current building safety function and building vulnerability (without regard for or information about a damaging natural forces event) is provided.

Wagenblast, G.R., Westinghouse Hanford

1996-09-12

251

Effectiveness of Enhanced Safety Management  

SciTech Connect

This paper discusses the development of an Enhanced Safety Management (ESM) campaign to improve safety and reduce risk in oil and gas exploration. The essentials of ESM are summarized by the author. The paper addresses the method developed to implement ESM and how the control of process designs to control operations minimizes the risk of a major accident.

Waterfall, K.W. (Sarawak Shell Bhd. (MY))

1988-01-01

252

Automatic authoring in the LAOS AHS authoring model  

Microsoft Academic Search

In this paper, we extend the automatic authoring techniques that can be built based on the LAOS model, a five-layer AHS authoring model. As the LAOS model itself is fairly complex, although information-rich, an adaptive hypermedia author needs a lot of system support to be able to populate all its levels with the corresponding information. Therefore, such automatic authoring techniques,

Alexandra I. Cristea

2003-01-01

253

School Safety in France.  

ERIC Educational Resources Information Center

|Describes the "Observatoire national de la securite des etablissements scolaires et d'enseignement superieur," a national agency established by the French government in 1995 to ensure safety in schools and colleges. Its annual reports, drawn up in conjunction with experts, are sent out to government, public authorities, and any stakeholders with…

PEB Exchange, 2003

2003-01-01

254

School Security and Safety.  

ERIC Educational Resources Information Center

The author contends that safety and accident prevention should be given primary consideration in a school system's risk management program. He argues that accidents and losses are symptoms of defects in the management system. Two classes of loss discussed are (1) accidental -- injury/loss resulting from unintended events; and (2) purposeful --…

Licht, Kenneth F.

255

Robotic safety  

SciTech Connect

The introduction of industrial robots in the workplace has improved safety by reducing human exposure to some of the traditional hazardous tasks and environments, yet at the same time robots have introduced new hazards in the workplace. There are currently no national consensus standards for robotic safety in the US. This report discusses the hazards associated with industrial robots and provides safety guidelines to protect workers from these hazards. In conclusion, it is the responsibility of manufacturers and users of industrial robots to develop and implement robotic safety guidelines for each application to ensure worker safety. 13 references.

Kessel, D.S.

1984-10-01

256

47 CFR 90.437 - Posting station licenses.  

Code of Federal Regulations, 2012 CFR

...2012-10-01 false Posting station licenses. 90.437...Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED...90.437 Posting station licenses. (a...authorization for each base or fixed station at a fixed...

2012-10-01

257

47 CFR 90.437 - Posting station licenses.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 false Posting station licenses. 90.437...Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED...90.437 Posting station licenses. (a...authorization for each base or fixed station at a fixed...

2011-10-01

258

76 FR 74585 - Railroad Workplace Safety; Adjacent-Track On-Track Safety for Roadway Workers  

Federal Register 2010, 2011, 2012, 2013

...publication. FRA is not authorized to impose a penalty on persons for violating information...214 Occupational safety and health, Penalties, Railroad safety. The Final Rule...Appendix A to Part 214--Schedule of Civil Penalties...

2011-11-30

259

Efficacy and safety of a subacromial continuous ropivacaine infusion for post-operative pain management following arthroscopic rotator cuff surgery: A protocol for a randomised double-blind placebo-controlled trial  

Microsoft Academic Search

BACKGROUND: Major shoulder surgery often results in severe post-operative pain and a variety of interventions have been developed in an attempt to address this. The continuous slow infusion of a local anaesthetic directly into the operative site has recently gained popularity but it is expensive and as yet there is little conclusive evidence that it provides additional benefits over other

Jennifer A Coghlan; Andrew Forbes; Simon N Bell; Rachelle Buchbinder

2008-01-01

260

Authors as Citers over Time.  

ERIC Educational Resources Information Center

|Explores the tendency of authors to re-cite themselves and others in multiple works over time, using the insights gained to build citation theory. Defines the set of all authors whom an author cites as that author's citation identity. As illustrated by the top re-citees of the eight information scientists selected as test cases, identities are…

White, Howard D.

2001-01-01

261

Safety in Riding Programs: A Director's Guide.  

ERIC Educational Resources Information Center

|Camp riding programs should be examined regularly for liability and risk management issues. Elements of a basic safety assessment include requiring proper safety apparel, removing obstructions from riding rings, ensuring doors and gates are closed, requiring use of lead ropes, securing equine medications, banning smoking, posting written…

Kpachavi, Teresa

1996-01-01

262

PILOTS Database Instruments Authority List.  

National Technical Information Service (NTIS)

Lists all projective tests, self-report questionnaires, structured interviews, and other assessment instruments that have been used in papers indexed in the PILOTS database, an electronic index to published literature on post-traumatic stress disorder and...

F. Lerner

1995-01-01

263

Pilots Database: Instruments Authority List.  

National Technical Information Service (NTIS)

Lists all projective tests, self-report questionnaires, structured interviews, and other instruments that have been used in papers indexed in the PILOTS database, and electronic index to published literature on post-traumatic stress disorder and other men...

F. Lerner

2001-01-01

264

Nuclear Safety  

SciTech Connect

This review journal covers significant developments in the field of nuclear safety. Its scope includes the analysis and control of hazards associated with nuclear energy, operations involving fissionable materials, and the products of nuclear fission and their effects on the environment. Primary emphasis is on safety in reactor design, construction, and operation; however, the safety aspects of the entire fuel cycle, including fuel fabrication, spent-fuel processing, nuclear waste disposal, handling of radioisotopes, and environmental effects of these operations, are also treated.

Not Available

1992-01-01

265

The Allure of Authors: Author Studies in the Elementary Classroom.  

ERIC Educational Resources Information Center

|Noting that readers of all ages seek out favorite authors, this book offers a model that encourages readers to respond aesthetically, biographically, and critically to an author's literature. At the heart of the book are four author studies that were implemented with children at various grade levels. These studies span the genres of picture…

Jenkins, Carol Brennan

266

14. Typical interior stairwell, demonstrating bannister and post. The grating ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. Typical interior stairwell, demonstrating bannister and post. The grating is a safety device to prevent falls. - Roanoke Veterans Administration Hospital, Building No. 6, 1970 Roanoke Boulevard, Salem, Salem, VA

267

Post-harvest seedling recruitment following mountain pine beetle ...  

Treesearch

Title: Post-harvest seedling recruitment following mountain pine beetle infestation of ... pine beetle (Dendroctonus ponderosae Hopkins) has created management ... wildfire risk, human safety, and scenic, wildlife, and watershed resources in ...

268

Lab Safety  

NSDL National Science Digital Library

The North Carolina Community College System BioNetwork's interactive eLearning tools (IETs) are reusable chunks of training that can be deployed in a variety of courses or training programs. IETs are designed to enhance, not replace hands-on training. Learners are able to enter a hands-on lab experience better prepared and more confident. This particular IET delves into laboratory safety, and covers interacting with the lab environment and a new lab partner. Topics covered include proper dress, housekeeping, safety equipment, mixing, fire safety, and spills. When the module is completed, visitors will be able to demonstrate proper lab safety techniques.

2012-11-06

269

Pedestrian Safety  

MedlinePLUS

... should go here Social Media ACEP in Social Media Campaigns Campaigns Read Patient Stories Health News About Emergencies Childhood / Student Emergencies Diseases & Infections Disaster Preparedness Elderly Safety ...

270

Nuclear Safety  

SciTech Connect

Nuclear Safety is a review journal that covers significant developments in the field of nuclear safety. Its scope includes the analysis and control of hazards associated with nuclear energy, operations involving fissionable materials, and the products of nuclear fission and their effects on the environment. Primary emphasis is on safety in reactor design, construction, and operation; however, the safety aspects of the entire fuel cycle, including fuel fabrication, spent-fuel processing, nuclear waste disposal, handling of radioisotopes, and environmental effects of these operations, are also treated.

Silver, E.G. (ed.)

1990-01-01

271

5 CFR 591.204 - Who can receive COLAs and post differentials?  

Code of Federal Regulations, 2013 CFR

... 2013-01-01 false Who can receive COLAs and post differentials? 591.204 Section...Differentials § 591.204 Who can receive COLAs and post differentials? (a) Agencies pay COLAs and post differentials authorized...

2013-01-01

272

10 CFR 35.2024 - Records of authority and responsibilities for radiation protection programs.  

Code of Federal Regulations, 2013 CFR

...Records of authority and responsibilities for radiation protection programs. 35.2024 Section...of authority and responsibilities for radiation protection programs. (a) A...duties, and responsibilities of the Radiation Safety Officer as required by §...

2013-01-01

273

46 CFR 2.01-30 - Delegation of OCMI signature authority.  

Code of Federal Regulations, 2011 CFR

...Delegation of OCMI signature authority. The Officer in Charge, Marine Inspection, may redelegate signature authority for documents issued under...and each Marine Safety Unit Commanding Officer within his or her...

2011-10-01

274

46 CFR 2.01-30 - Delegation of OCMI signature authority.  

Code of Federal Regulations, 2012 CFR

...Delegation of OCMI signature authority. The Officer in Charge, Marine Inspection, may redelegate signature authority for documents issued under...and each Marine Safety Unit Commanding Officer within his or her...

2012-10-01

275

The safety leadership.  

PubMed

In this paper the authors present a careful consideration about the role of leadership, the fundamental element for the success of Behavior-Based Safety (B-BS) programs within companies. Lees and Faulkner have been training, coaching and writing about Behavior-Based Safety for the last ten years. Considerable data has been gathered during this process and the paramount factor in its success is leadership. An effective leader can create many spectacular successes. The success stories are all predicated on good leadership, without that a good product, great processes and quality people are all wasted and often find themselves on the rocks of frustration. PMID:20518204

Lees, Howard; Faulkner, Bruce

276

Defying Unjust Authority: An Exploratory Study.  

PubMed

This research explores the psychological factors potentially involved in fostering disobedience to an unjust authority. Our paradigm was modeled after that of the Utrecht Studies on Obedience (Meeus and Raaijmakers European Journal of Social Psychology 16:311-324, 1986) in which participants are ordered to give each of 15 increasingly hostile comments to a participant/victim whenever he fails a trial. Although 30% of our sample followed commands to insult the other participant (confederate), the majority did refuse to do so at some point in the escalating hostility sequence. Our procedure utilized conditions known from prior research to increase the ratio of disobedience to obedience: proximity of teacher to learner plus remote authority. In order to better understand some of the cognitive and affective processes that may predict such defiant behaviour, we utilized a variety of measures, among them, behavioural observations, individual difference assessments, and in depth post-experimental interviews. PMID:20461226

Bocchiaro, Piero; Zimbardo, Philip G

2010-05-01

277

Post-Traumatic Stress Disorder (PTSD)  

MedlinePLUS

... may be helpful in improving the symptoms of PTSD. More research is needed to fully understand the safety and ... pdf. Accessed Jan. 5, 2011. Nakell L. Adult post-traumatic stress disorder: Screening and treating in primary care. ... Accessed Jan. 5, 2011. ...

278

Expansion of passive safety function  

SciTech Connect

Expansion of the use of passive safety functions is proposed. Two notions are presented. One is that, in the design of passive safety nuclear reactors where aversion of active components is stressed, some active components are purposely introduced, by which a system is built in such a way that it behaves in an apparently passive manner. The second notion is that, instead of using a passive safety function alone, a passive safety function is combined with some active components, relating the passivity in the safety function with enhanced controllability in normal operation. The nondormant system which the authors propose is one example of the first notion. This is a system in which a standby safety system is a portion of the normal operation system. An interpretation of the nondormant system via synergetics is made. As an example of the second notion, a PIUS density lock aided with active components is proposed and is discussed.

Inai, Nobuhiko; Nei, Hiromichi; Kumada, Toshiaki

1995-07-01

279

Parental Authority in Divorced Families  

Microsoft Academic Search

This work examines the possible differences between divorced mothers and mothers of intact families in their inclinations to exert parental authority, and the possible relationship between the degree of parental authority and children's personal and social adjustment. For the purposes of the study, we developed the Haifa Parental Authority Questionnaire, which is a situation-depicted test based on a conceptual analysis

Amnon Lazar; Joseph Guttmann; Liat Abas

2009-01-01

280

Enhancing Author's Voice through Scripting  

ERIC Educational Resources Information Center

|The authors suggest using scripting as a strategy to mentor and enhance author's voice in writing. Through gradual release, students use authentic literature as a model for writing with voice. The authors also propose possible extensions for independent practice, integration across content areas, and tips for evaluation.|

Young, Chase J.; Rasinski, Timothy V.

2011-01-01

281

EASE: Evolutional Authoring Support Environment  

Microsoft Academic Search

How smart should we be in order to cope with the complex authoring process of smart courseware? Lately this question gains more attention with attempts to simplify the process and efforts to define authoring systems and tools to support it. The goal of this paper is to specify an evolutional perspective on the Intelligent Educational Systems (IES) authoring and in

Lora Aroyo; Akiko Inaba; Larisa N. Soldatova; Riichiro Mizoguchi

2004-01-01

282

Authority Control on the Web.  

ERIC Educational Resources Information Center

|This paper discusses how the authority control performed by libraries can help the World Wide Web and suggests some next steps in making this resource of authority records available and used internationally. Topics addressed include: (1) characteristics of the Web; (2) precision and recall; (3) connecting international authority files, including…

Tillett, Barbara B.

283

Robot safety  

Microsoft Academic Search

An overview of the analysis which should be undertaken with regard to safety where robotic systems are used. Looks at accidents associated with these systems and the legislation covering their operation in the workplace. Outlines general guidelines for robotic system design, implementation and maintenance and the various factors which should be considered with regard to safety. Describes a proposed International

G R Ward; S R G Went

1995-01-01

284

Robotic safety  

Microsoft Academic Search

The introduction of industrial robots in the workplace has improved safety by reducing human exposure to some of the traditional hazardous tasks and environments, yet at the same time robots have introduced new hazards in the workplace. There are currently no national consensus standards for robotic safety in the US. This report discusses the hazards associated with industrial robots and

Kessel

1984-01-01

285

Safety Matters  

Microsoft Academic Search

As a result of Columbine and other events, states and districts across the United States have responded with vigor to a call for a renewed focus on school safety. This paper examined one such effort undertaken by Harrison County Public Schools, located in West Virginia. The district received federal funding for surveillance equipment used to enhance safety efforts at middle

Ethan Heinen; Jaci Webb-Dempsey; Lucas Moore; Craig McClellan; Carl Friebel

2007-01-01

286

Safety Systems  

ERIC Educational Resources Information Center

|Colleges across the country are rising to the task by implementing safety programs, response strategies, and technologies intended to create a secure environment for teachers and students. Whether it is preparing and responding to a natural disaster, health emergency, or act of violence, more schools are making campus safety a top priority. At…

Halligan, Tom

2009-01-01

287

Safety First  

ERIC Educational Resources Information Center

|Ned Miller does not take security lightly. As director of campus safety and emergency management at the Des Moines Area Community College (DMACC), any threat requires serious consideration. As community college administrators adopt a more proactive approach to campus safety, many institutions are experimenting with emerging technologies,…

Taft, Darryl

2011-01-01

288

Safety First!  

NSDL National Science Digital Library

Working with young children and chemicals requires attention to safety. This article details the experiences of a third-grade teacher who used a "disaster" to create a hands-on inquiry that introduces children to chemistry safety during a third-grade acid/base exploration.

Longfield, Judith

2006-02-01

289

Nuclear Power - Post Fukushima  

NASA Astrophysics Data System (ADS)

The extreme events that led to the prolonged power outage at the Fukushima Daiicchi nuclear plant have highlighted the importance of assuring a means for stable long term cooling of the nuclear fuel and containment following a complete station blackout. Legislative bodies, regulatory agencies and industry are drawing lessons from those events and considering what changes, if any, are needed to nuclear power, post Fukushima. The enhanced safety of a new class of reactor designed by NuScale Power is drawing significant attention in light of the Fukushima events. During normal operation, each NuScale containment is fully immersed in a water-filled stainless steel lined concrete pool that resides underground. The pool, housed in a Seismic Category I building, is large enough to provided 30 days of core and containment cooling without adding water. After 30 days, the decay heat generations coupled with thermal radiation heat transfer is completely adequate to remove core decay heat for an unlimited period of time. These passive power systems can perform their function without requiring an external supply of water of power. An assessment of the NuScale passive systems is being performed through a comprehensive test program that includes the NuScale integral system test facility at Oregon State University

Reyes, Jose, Jr.

2011-10-01

290

42 CFR 84.310 - Post-approval testing.  

Code of Federal Regulations, 2012 CFR

...2012-10-01 false Post-approval testing. 84.310 Section 84...SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY...84.310 Post-approval testing. (a) NIOSH will periodically...c) NIOSH will conduct such testing pursuant to the methods...

2012-10-01

291

A Prospective, Open-label Study to Compare the Efficacy and the Safety of Topical Loteprednol Etabonate and Topical Flurbiprofen Sodium in Patients with Post-Operative Inflammation after Cataract Extraction  

PubMed Central

Purpose To study the effect of the topical Non-Steroidal Anti Inflammatory Drug (NSAID), Flurbiprofen 0.03%, as an alternative to the topical steroids for the postoperative control of inflammation in cataract surgeries. Methods The effect of the topical NSAID, flurbiprofen sodium 0.03%, was studied and compared with that of the topical steroid – Loteprednol etabonate 0.5% suspension (as eye drops) in a prospective, open labelled study. Both the groups (20 patients each) were similar in the baseline parameters. The postoperative inflammatory response following the standard, small incision, extra capsular cataract extraction was assessed in both the groups for 28 post-operative days. The parameters which were considered for the study were conjunctival hyperaemia, ciliary congestion, corneal oedema, cells in the anterior chamber, aqueous flare and ocular pain. The severity of the postoperative inflammatory responses for both the drugs was graded on the post-operative days 1, 7, 14, 21 and 28 and it was statistically analyzed. Results The 2 groups did not differ statistically in the effect of the treatment for any of the variables, which included aqueous cells, flare, ciliary congestion and conjunctival congestion (p< 0.001). Both the drugs were well tolerated and no severe adverse Drug Reactions (ADRs) were caused by the topical NSAID and the topical steroid. Conclusion The topical NSAID, Flurbiprofen, is as effective as the topical corticosteroid, Loteprednol and it can be used as an alternative in the routine postoperative treatment following uncomplicated cataract surgeries.

Bannale, Sheshidhar G.; Pundarikaksha, H.P.; Sowbhagya, H.N.

2012-01-01

292

31 CFR 586.515 - Payments for services rendered by the Government of the FRY (S&M) to aircraft authorized...  

Code of Federal Regulations, 2010 CFR

...FRY (S&M) to aircraft authorized; aircraft and maritime safety. 586.515 Section 586.515 Money and Finance...FRY (S&M) to aircraft authorized; aircraft and maritime safety. (a) Payments to the Government of the...

2010-07-01

293

31 CFR 586.515 - Payments for services rendered by the Government of the FRY (S&M) to aircraft authorized...  

Code of Federal Regulations, 2010 CFR

...FRY (S&M) to aircraft authorized; aircraft and maritime safety. 586.515 Section 586.515 Money and Finance...FRY (S&M) to aircraft authorized; aircraft and maritime safety. (a) Payments to the Government of the...

2009-07-01

294

Author! Author! Jan Brett: Hedgehogs, Trolls, and a Gingerbread Baby  

ERIC Educational Resources Information Center

|This column presents a brief biography of author Jan Brett. According to Jan Brett's official webpage, there have been more than twenty-eight million of her books printed. Her titles can always be found on the best-selling children's book author/illustrator lists. Brett is one of the most beloved and recognized children's book illustrators and is…

Brodie, Carolyn S.

2005-01-01

295

Networking and Authority Control: Online Catalog Authority Control in Illinois.  

ERIC Educational Resources Information Center

|Discussion of online authority control in library catalogs highlights a system for shared authority work among libraries participating in the Illinois statewide online union catalog, ILLINET Online. Topics discussed include the design of the ILLINET Online database; staff training procedures; documentation in the form of manuals; communication;…

Henigman, Barbara

1991-01-01

296

The Author-Topic Model for Authors and Documents  

Microsoft Academic Search

We introduce the author-topic model, a gen- erative model for documents that extends La- tent Dirichlet Allocation (LDA; Blei, Ng, & Jordan, 2003) to include authorship informa- tion. Each author is associated with a multi- nomial distribution over topics and each topic is associated with a multinomial distribution over words. A document with multiple au- thors is modeled as a

Michal Rosen-Zvi; Thomas L. Griffiths; Mark Steyvers; Padhraic Smyth

2004-01-01

297

Challenges to Legitimacy in Food Safety Governance? The Case of the European Food Safety Authority (EFSA)  

Microsoft Academic Search

The ‘old’ forms of governance have been criticized for being neither sufficiently democratic nor effective. The popularity of ‘new’ modes of governance includes the embracing of values — integral to democratic processes — such as legitimacy, public accountability and trust. By relating parts of this ‘old?vs.?new’ distinction to March and Olsen’s dichotomy of aggregative vs. integrative political processes, the aim

Mikael Klintman; Annica Kronsell

2010-01-01

298

What Authors and Illustrators Do  

NSDL National Science Digital Library

This project will connect you with several author/illustrator websites and interviews that show what processes they have to go through to create their stories and/or illustrations. AUTHORS Pre-Lesson Activity Have students (in pairs or small groups) list different tasks/steps an author will take when writing a book. After they have their lists call on different groups to tell you one thing they have written down. If the other groups have ...

B, Miss

2009-07-09

299

[Unguis incarnatus syndrome (author's transl)].  

PubMed

Authors establish the occurrence of unguis incarnatus syndrome of Steigleder and Stober-Münster in 114 patients with ingrowing nails. Disturbed carbohydrate metabolism deserves particular attention. PMID:7222890

Reszler, M; Mari, B

1981-02-01

300

The Author and His Work  

ERIC Educational Resources Information Center

|Continuing series on contemporary Spanish authors. Covers the writings of Alonso Zamora Vicente, Ramon de Garciasol, Julio Manegat, Concha Castroviejo, Carlos Muniz, and Angel Palomino Jimenez. (DS)|

Spain Today, 1972

1972-01-01

301

Unreviewed safety question determination application guide  

SciTech Connect

The basic purpose of the Unreviewed Safety Question Determination (USQD) process is to ascertain if a change to a facility can be made without a prior safety review and approval by the original approving body. The USQD process judges whether the change could result in the facility being outside its authorization basis. If the change could result in the facility being outside its authorization basis, the change involves an Unreviewed Safety Question (USQ). The authorization basis consists of those aspects of the facility design basis relied upon by the original approving body to authorize operation. The authorization basis would typically include the facility Safety Analysis Report, Technical Safety Requirements (TSRs), Operational Safety Requirements (OSRs), Technical Specifications, DOE-issued Safety Evaluation Reports, Safety Analysis Report Update Program documents, Safety Studies, Safety Assessments, Risk Assessments, Facility Safety Evaluations, and any applicable commitments made to comply with Department of Energy (DOE) orders or policies. Steps in the USQD process include defining the changes being evaluated; evaluating the process by which the change is accomplished; then the potential effects of the change are compared to the authorization basis for the facility to determine if the change could result in the facility being outside is authorization basis. The USQD will provide input to the change control board for facilities placed under configuration management to aid their understanding of the extent of a proposed change and whether or not the change should be authorized. The USQD will also provide input to the categorization of reportable occurrences under DOE Order 5000.3A, Occurrence Reporting and Processing of Operations Information. This report provides an overview of the steps in the USQD process and detailed instructions and examples intended primarily for use by the personnel who perform, review, and approve the USQDs. 3 refs., 3 figs.

Not Available

1991-09-01

302

Aerospace Safety  

NSDL National Science Digital Library

This site from SpaceTEC National Aerospace Technical Education Center presents materials on aerospace safety. Topics include hazard communications, lockout/tagout, confined space entry, fall protection, PPE, firefighting and bloodborne pathogens.

2010-10-18

303

Robotic Safety.  

National Technical Information Service (NTIS)

The introduction of industrial robots in the workplace has improved safety by reducing human exposure to some of the traditional hazardous tasks and environments, yet at the same time robots have introduced new hazards in the workplace. There are currentl...

D. S. Kessel

1984-01-01

304

Auto Safety  

MedlinePLUS

... until they have reached the maximum weight and height limits recommended by the manufacturer. Many parents have ... a crash. So it's essential to follow the height and weight guidelines on the child safety seat ...

305

Skateboarding Safety  

MedlinePLUS

... SAFETY Like other sports activities, skateboarding has risks. Vehicle traffic, trick riding, and excessive speed can lead ... t become another statistic. ? Stay clear of moving vehicles. Some of the most common and severe skateboarding ...

306

Bike Safety  

MedlinePLUS

... have to wear special clothing to enjoy the sport of biking. But the right clothing can increase ... MORE ON THIS TOPIC Getting Exercise in College Sports and Exercise Safety Choosing the Right Sport for ...

307

Lawnmower Safety  

MedlinePLUS

... not remove safety devices, shields, or guards on switches. Add fuel before starting the engine, not when ... mower from tipping over. Do not cut wet grass. Top of page Last reviewed: March 2012 AAOS ...

308

Evaluation of autoimmune safety signal in observational vaccine safety studies  

PubMed Central

Autoimmune safety evaluation is an important component of post-licensure vaccine safety evaluation. Recently, we published the findings from a large observational safety study of the quadrivalent human papillomavirus vaccine in females. From this study, based on two large managed care organizations, we have obtained some empirical data that may prove useful for the design of future vaccine safety studies within a managed care environment. For autoimmune conditions, a major challenge in vaccine safety study is to determine true incident cases in relation to the timing of vaccination. We found expert case review of medical records an indispensable component for autoimmune safety studies based on electronic health records. Case identification should also be expanded to include the use of laboratory test results or other relevant measures in addition to the disease specific ICD-9 diagnosis codes, when applicable. Furthermore, we recommend the parallel use of both safety signal evaluation that involves pattern evaluation for conditions that are more common, and statistical comparisons for conditions that are rather rare. Finally, we recommend an accompanying vaccine uptake study to understand the potential selection bias and confounding in a given study population that should be addressed with data collection and analytical techniques.

Chao, Chun; Jacobsen, Steven

2012-01-01

309

Safety Guidelines  

NSDL National Science Digital Library

In order for students to inquire confidently, we must create safe classroom environments. Safety is not just a set of rules but a state of mind, and perhaps, most importantly, it is an attitude and a set of skills that carry over into a students' daily life. But research also shows that the space in which students inquire is vital to their safety and security. This chapter summarizes some of the important factors that contribute to safe laboratory environments.

Biehle, James T.; Motz, Lamoine L.; West, Sandra S.

2007-01-01

310

Safety Information  

Center for Drug Evaluation (CDER)

... Etanercept (Enbrel), Immunex Corp., Post-marketing reports of adverse events of rare cases of nervous system disorders including demyelinating ... More results from www.fda.gov/drugs/developmentapprovalprocess/howdrugsaredevelopedandapproved

311

Measuring patient safety culture in Taiwan using the Hospital Survey on Patient Safety Culture (HSOPSC)  

Microsoft Academic Search

BACKGROUND: Patient safety is a critical component to the quality of health care. As health care organizations endeavour to improve their quality of care, there is a growing recognition of the importance of establishing a culture of patient safety. In this research, the authors use the Hospital Survey on Patient Safety Culture (HSOPSC) questionnaire to assess the culture of patient

I-Chi Chen; Hung-Hui Li

2010-01-01

312

Retrofitting Software Safety in an Implantable Medical Device  

Microsoft Academic Search

Regulatory agencies are requiring companies to systematically demonstrate software safety in their implantable devices, even those already developed. The authors devised a rigorous software safety analysis technique and applied it to a nearly-completed cardiac rhythm management device. They were able to identify safety faults, modify the software to mitigate them, and verify overall safety

Ramin Mojdehbakhsh; Wei-tek Tsai; Shekhar H. Kirani; Lynn Elliott

1994-01-01

313

Safety Education--An Essential Element of Technical Training  

ERIC Educational Resources Information Center

After tracing the background of the safety movement, provisions of recent safety legislation, and the ecological and environmental impact of industrial processes, the author stresses the need for safety education in technical education programs to prepare future employees for industrial safety requirements. (MF)

Glazener, Everett R.; Comstock, Thomas W.

1978-01-01

314

Risk management for distributed authorization  

Microsoft Academic Search

Distributed authorization takes into account several elements, includ- ing certiflcates that may be provided by non-local actors. While most trust management systems treat all assertions as equally valid up to certiflcate authentication, realistic considerations may associate risk with some of these elements, for example some actors may be less trusted than others. Furthermore, practical online authorization may require certain levels

Christian Skalka; Xiaoyang Sean Wang; Peter C. Chapin

2007-01-01

315

The Classes of Authoring Programs.  

ERIC Educational Resources Information Center

|Provides an overview of developments in authoring tools and describes ways to categorize products by platform, type of end-product, sophistication of end-product, and authoring metaphor. Discusses products from AimTech, Allegiant, Allen Communication, Asymetrix, Corel, Discovery Systems International, Enigma, Harrow Media, Horizons, Innovus,…

Kozel, Kathy

1997-01-01

316

Young Chinese Children's Authority Concepts  

ERIC Educational Resources Information Center

Using multilevel analyses, we examined the influence of domain (moral, conventional, and personal) and the familiarity of different authority figures (mother, teacher, person in charge, and stranger) in public, school, or home settings in 123 four to seven-year-old Chinese children (M = 5.6 years) in Hong Kong. Children affirmed authority more for…

Yau, Jenny; Smetana, Judith G.; Metzger, Aaron

2009-01-01

317

The Author and the Reviewers.  

ERIC Educational Resources Information Center

The diversity of textbook and scholarly book reviewers makes it difficult for an author to deal with reviews in any systematic or preplanned manner. There are, however, several helpful working assumptions: (1) the reviewer is always right, (2) the author is always right in principle but frequently wrong in practice, (3) the publisher wants what…

DeVito, Joseph A.

318

Political Authority and Bureaucratic Resilience  

Microsoft Academic Search

This article discusses the nature of administrative reform in Japan. It analyses government strategies of reform in relation to the nature of bureaucracy and political authority. There is interaction between bureaucrats and politicians, characterized by cooperation among those sharing common expertise. However, such cooperation results in weaker political authority over bureaucracy. Administrative reform in Japan has not failed entirely, but

Shun'ichi Furukawa

1999-01-01

319

Powells.com: Author Interviews  

NSDL National Science Digital Library

A number of publishing houses and well-regarded independent booksellers have placed author interviews on their respective Web sites, but this particular one from the massive Powell's Books in Portland, Oregon may be one of the most intriguing online collections available. Containing over 50 interviews, the authors profiled here include Ann Patchett, David Halberstam, Paul Theroux, Susan Orlean, and Deepak Chopra. Several of the interviews are particularly interesting, including the one conducted with Erik Larson (author of The White City, a tale that intertwines different stories about late 19th century Chicago together) and one with Michael Chabon, the author who won the Pulitzer Prize for the Amazing Adventures of Kavalier & Clay. Finally, visitors have the opportunity to take a look at related publications from Powell's, such as a compilation of lengthy interviews with 22 different authors.

320

ONSITE TRANSPORTATION AUTHORIZATION CHALLENGES AT THE SAVANNAH RIVER SITE  

SciTech Connect

Prior to 2008, transfers of radioactive material within the Savannah River Site (SRS) boundary, referred to as onsite transfers, were authorized by Transportation Safety Basis (TSB) documents that only required approval by the SRS contractor. This practice was in accordance with the existing SRS Transportation Safety Document (TSD). In 2008 the Department of Energy Savannah River Field Office (DOE-SR) requested that the SRS TSD be revised to require DOE-SR approval of all Transportation Safety Basis (TSB) documents. As a result, the primary SRS contractor embarked on a multi-year campaign to consolidate old or generate new TSB documents and obtain DOE-SR approval for each. This paper focuses on the challenges incurred during the rewriting or writing of and obtaining DOE-SR approval of all Savannah River Site Onsite Transportation Safety Basis documents.

Watkins, R.; Loftin, B.; Hoang, D.; Maxted, M.

2012-05-30

321

48 CFR 1450.102-1 - Delegation of authority.  

Code of Federal Regulations, 2011 CFR

...CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 1450.102-1 Delegation of authority. The AS/PMB shall approve all actions under FAR Part 50, except for actions in excess of $55,000, actions which increase the contract...

2011-10-01

322

48 CFR 1450.102-1 - Delegation of authority.  

Code of Federal Regulations, 2012 CFR

...CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 1450.102-1 Delegation of authority. The AS/PMB shall approve all actions under FAR Part 50, except for actions in excess of $55,000, actions which increase the contract...

2012-10-01

323

Lightning protection of full authority digital electronic systems  

Microsoft Academic Search

Modern electronic systems are vulnerable to transient and they now provide safety critical functions such as full authority digital electronic control (FADEC) units for fly by wire aircraft. Of the traditional suppression technologies available diodes have gained the wider acceptance, however, they lack the current handling capacity to meet existing threat levels. The development of high speed fold back devices

David Crofts

1991-01-01

324

47 CFR 78.33 - Special temporary authority.  

Code of Federal Regulations, 2012 CFR

...written request shall be submitted within ten (10) days thereafter. (b...safety of life and property; (10) Plate power input to final radio frequency stage...temporary authority shall be filed at least ten (10) days prior to the date of...

2012-10-01

325

47 CFR 78.33 - Special temporary authority.  

Code of Federal Regulations, 2011 CFR

...written request shall be submitted within ten (10) days thereafter. (b...safety of life and property; (10) Plate power input to final radio frequency stage...temporary authority shall be filed at least ten (10) days prior to the date of...

2011-10-01

326

Hanford Generic Interim Safety Basis  

SciTech Connect

The purpose of this document is to identify WHC programs and requirements that are an integral part of the authorization basis for nuclear facilities that are generic to all WHC-managed facilities. The purpose of these programs is to implement the DOE Orders, as WHC becomes contractually obligated to implement them. The Hanford Generic ISB focuses on the institutional controls and safety requirements identified in DOE Order 5480.23, Nuclear Safety Analysis Reports.

Lavender, J.C.

1994-09-09

327

Tutorial for Authors and Referees  

NASA Astrophysics Data System (ADS)

Editors from Physical Review Letters and Physical Review will provide information and tips for our less experienced referees and authors. This session is aimed at anyone looking to submit to or review for any of the APS journals, as well as anyone who would like to learn more about the authoring and refereeing processes. Topics for discussion will include advice on how to write good manuscripts, similarities and differences in writing referee reports for PRL and PR, and other ways in which authors, referees, and editors can work together productively. Following a short presentation from the editors, there will be a moderated discussion. Refreshments will be served.

Pm–3:30PM

2012-03-01

328

Indiana Authors and Their Books  

NSDL National Science Digital Library

The Hoosier State has produced its share of well-known authors, including Theodore Dreiser, Booth Tarkington, and James Whitcomb Riley. This remarkable project from Indiana University digitized the three-volume reference work, "Indiana Authors and Their Books," which covers the years from 1816 to 1980 and contains approximately 7,000 author entries. The project was made possible via funding from the Institute of Museum and Library Services and visitors can make their way through the finished effort here. Visitors may browse by Authors, Books, or Years, or search for a particular term. Regardless of where one starts their exploration within this troika, they will end up spending more time here than originally planned.

329

The Author and His Works  

ERIC Educational Resources Information Center

Works of Emilio Garcia Gomez, Dario Fernandez Florez, Armando Lopez Salinas, Jaime de Arminan, Luis Lopez Anglada, and Carmen Bravo Villasante are analyzed in this continuing series on Spanish authors. (DS)

Spain Today, 1971

1971-01-01

330

Elkhorn ruling boosts state authority  

Microsoft Academic Search

On 31 May 1994, a landmark U.S. Supreme Court decision expanded state authority to establish conditions to protect water quality and included stream flows, aesthetics, and, potentially, other elements in a broad definition of water quality. Called the {open_quotes}Elkhorn case{close_quotes} the Supreme Court ruled that the state of Washington Department of Ecology has authority to set instream flows for fish

Beecher

1995-01-01

331

Tank Farms Technical Safety Requirements [VOL 1 and 2  

SciTech Connect

The Technical Safety Requirements (TSRs) define the acceptable conditions, safe boundaries, basis thereof, and controls to ensure safe operation during authorized activities, for facilities within the scope of the Tank Waste Remediation System (TWRS) Final Safety Analysis Report (FSAR).

CASH, R.J.

2000-12-28

332

OSHA Laboratory Standard: Driving Force for Laboratory Safety!  

ERIC Educational Resources Information Center

Discusses the Occupational Safety and Health Administration's (OSHA's) Laboratory Safety Standards as the major driving force in establishing and maintaining a safe working environment for teachers and students. (Author)

Roy, Kenneth R.

2000-01-01

333

OSHA Laboratory Standard: Driving Force for Laboratory Safety!  

ERIC Educational Resources Information Center

|Discusses the Occupational Safety and Health Administration's (OSHA's) Laboratory Safety Standards as the major driving force in establishing and maintaining a safe working environment for teachers and students. (Author)|

Roy, Kenneth R.

2000-01-01

334

75 FR 5172 - Solicitation of Nominations for Members of the Transit Rail Advisory Committee for Safety  

Federal Register 2010, 2011, 2012, 2013

...Nominations for Members of the Transit Rail Advisory Committee for Safety AGENCY...for individuals to serve on the Transit Rail Advisory Committee for Safety (TRACS...and regulations for enhancing safety in rail transit should FTA be given authority...

2010-02-01

335

7 CFR 2.53 - Administrator, Food Safety and Inspection Service.  

Code of Federal Regulations, 2010 CFR

... 2009-01-01 false Administrator, Food Safety and Inspection Service. 2.53 Section...Delegations of Authority by the Under Secretary for Food Safety § 2.53 Administrator, Food Safety and Inspection Service. (a)...

2009-01-01

336

7 CFR 2.53 - Administrator, Food Safety and Inspection Service.  

Code of Federal Regulations, 2010 CFR

... 2010-01-01 false Administrator, Food Safety and Inspection Service. 2.53 Section...Delegations of Authority by the Under Secretary for Food Safety § 2.53 Administrator, Food Safety and Inspection Service. (a)...

2010-01-01

337

Problems in Establishing a Name Authority File for Nigerian Authors.  

National Technical Information Service (NTIS)

Establishing name authority files in such multilingual nations as Nigeria is complicated by the existence of some 400 languages and dialects, although only about 15 percent of these have been written or used in publications--English is used as the officia...

B. S. Bankole

1979-01-01

338

Problems in Establishing a Name Authority File for Nigerian Authors.  

ERIC Educational Resources Information Center

Establishing name authority files in such multilingual nations as Nigeria is complicated by the existence of some 400 languages and dialects, although only about 15 percent of these have been written or used in publications--English is used as the official language and the medium of intercommunication between tribes. Traditionally, Nigerians have…

Bankole, Beatrice S.

339

Problems in Establishing a Name Authority File for Nigerian Authors.  

ERIC Educational Resources Information Center

|Establishing name authority files in such multilingual nations as Nigeria is complicated by the existence of some 400 languages and dialects, although only about 15 percent of these have been written or used in publications--English is used as the official language and the medium of intercommunication between tribes. Traditionally, Nigerians have…

Bankole, Beatrice S.

340

Author! Author! Amazing Cartoonist, Gifted Writer: William Steig  

ERIC Educational Resources Information Center

This article gives a brief biography of William Steig, one of America's best-known cartoonists and, later in life, a beloved children's author and illustrator. A major motion picture based on Steig's picture book "Shrek!" won the first Oscar in the category of best animated feature film in 2002. Steig passed away at the age of 95 in October, 2003.…

Brodie, Carolyn S.

2004-01-01

341

Prediction of post-post-perovskite transitions  

NASA Astrophysics Data System (ADS)

In the Earth, the post-perovskite structure is the final form of MgSiO3. However, in the solar giants and exoplanets in which pressure is much higher than the Earth, we can expect further phase transitions beyond the post-perovskite phase, i.e., post-post-perovskite transitions. Here we propose by first principles two candidates of crystalline post-post-perovskite phases of NaMgF3, which is a low-pressure analog of MgSiO3: U2S3-type and P63/mmc phases. Then we demonstrate that Al2O3 should undergo a transition to the U2S3-type phase at ~3.7 Mbar. This transformation should be important for the analysis of shock data in this pressure range, since alumina is used as window material. Our calculated compression curves agree with shock data excellently, suggesting the presence of two phase transitions (corundum-to-Rh2O3(II)-type and Rh2O3(II)-type-to-CaIrO3-type) in shock data. Our prediction also suggests that the multi-Mbar crystal chemistry of planet-forming minerals might be related to that of the rare-earth sulfides. Computations were performed at the Minnesota Supercomputing Institute. Research was supported by NSF grants EAR-0135533, EAR-0230319, and ITR-0428774 (VLab).

Umemoto, K.

2008-12-01

342

Post-Concussion Syndrome  

Microsoft Academic Search

\\u000a The post-concussion syndrome (a.k.a., post-concussive disorder and post concussional disorder) has been controversial for\\u000a decades. Without question, an acute post-concussion syndrome can be caused by the neurobiology of a mild traumatic brain injury (MTBI). Without question, a post-concussion\\u000a syndrome can be worsened by psychological distress, social psychological factors (e.g., the nocebo effect, iatrogenesis, and\\u000a misattributions), personality characteristics, and co-occurring conditions

Grant L. Iverson; Rael T. Lange

343

Online Safety.  

ERIC Educational Resources Information Center

|Describes provisions of Children's Internet Protection Act, which school districts are required to implement on or before October 31, 2001, involving the development and public dissemination of federally mandated Internet-safety policy to prevent minors from accessing inappropriate and harmful material. Provides suggestions to protect children…

Levine, Elliott

2001-01-01

344

Safety Resources.  

ERIC Educational Resources Information Center

|Lists 72 organizations and programs that deal with child safety, grouped by the following categories: (1) general; (2) general violence; (3) gun violence; (4) media violence; (5) drugs and alcohol; (6) child abuse and at-risk children; (7) parenting programs; (8) community service programs; (9) leadership programs; (10) peer counseling; (11)…

Hoot, James L.; Bartkowiak, Elaine T.

1994-01-01

345

Roadside Safety.  

National Technical Information Service (NTIS)

The 12 papers in the report deal with the following areas: some recent developments in timber pole safety by design; Pennsylvania's guide rail standards; a cost-effective change; events that produce occupant injury in longitudinal barrier accidents; low-m...

D. L. Ivey J. R. Morgan L. C. Schultz M. H. Ray J. D. Michie

1986-01-01

346

Farm Safety  

PubMed Central

Accident and safety are related terms; the higher the accident rate in any industry, the greater is the need for safety measures designed to prevent accidents. This article discusses the accident and safety problems in agriculture, which includes horticulture and forestry. There is still a tendency among townspeople to think of the countryside as peaceful and tranquil, a place where nothing happens very quickly and far removed from violent death or crippling injury. This pleasant rustic picture has undergone a striking change in the last 30 years owing to considerable agricultural mechanization and the development of chemical pesticides, which have brought new dangers to those who live and work on the land. Although men have readily adapted themselves to new machines and methods, they have not proved as able to recognize new dangers and learn how to guard against them. In consequence, accidents have increased to such an extent that the whole industry has realized the need for positive preventive measures. In this country, it is generally accepted that an employer of labour has a responsibility to provide safe working conditions for those he employs. Farm safety legislation goes a little further and usually requires an employer to provide necessary safeguards, with the added requirement on a worker to make use of them. It is a feature of accident prevention work that it never reaches a stage when it can be regarded as complete. Even when a reduction in accidents has been achieved, the effort must be sustained or the trend will be quickly reversed. Images

Wilson, G. S.

1966-01-01

347

Radiation Safety  

Microsoft Academic Search

Nursing and radiology staff members can have a difficult time coexisting and communicating as they strive to provide quality care for patients. Misconceptions about safe radiologic practice within the practice of perioperative nursing occur because members of these professional fields are unfamiliar with each other's knowledge and practice guidelines. This article provides an overview of radiologic practice and safety.

Michael Shymko; Tina Marie Shymko

1998-01-01

348

Cryogenics safety  

Microsoft Academic Search

The safety hazards associated with handling cryogenic fluids are discussed in detail. These hazards include pressure buildup when a cryogenic fluid is heated and becomes a gas, potential damage to body tissues due to surface contact, toxic risk from breathing air altered by cryogenic fluids, dangers of air solidification, and hazards of combustible cryogens such as liquified oxygen, hydrogen, or

Reider

1977-01-01

349

Bike Safety  

MedlinePLUS

... chirping. What could be more perfect than a bike ride? But wait! Before you pull your bike out of the garage, let's find out how ... two wheels. Why Is Bicycle Safety So Important? Bike riding is a lot of fun, but accidents ...

350

School Safety.  

ERIC Educational Resources Information Center

|The articles in this issue dealing with school safety discusses what rural and small urban settings are doing to prevent violence and to educate young people about prosocial alternatives to violence. The research is quite clear that female, minority, and gay students are the targets of a disproportionate amount of harassment and violence, both in…

The Newsletter of the Comprehensive Center-Region VI, 1999

1999-01-01

351

Effects of 28 days of resistance exercise while consuming commercially available pre- and post-workout supplements, NO-Shotgun® and NO-Synthesize® on body composition, muscle strength and mass, markers of protein synthesis, and clinical safety markers in males  

PubMed Central

Purpose The effects of 28 days of heavy resistance training while ingesting the pre- and post-workout supplements, NO-Shotgun® and NO-Synthesize® were determined on body composition, muscle strength and mass, markers of protein synthesis, and clinical safety markers. Methods Nineteen non-resistance-trained males participated in a resistance training program 4 times/week for 28 days while either ingesting 27 g/day of carbohydrate (CARB) or NO-Shotgun® 30 min pre-exercise and 27 g/day of carbohydrate or NO- Synthesize® 30 min post-exercise (NOSS). Data were analyzed with separate 2 × 2 ANOVA (p < 0.05). Results Total body mass was increased in both groups (p = 0.001), but not different between groups. Fat mass was unchanged with CARB, but NOSS decreased fat mass (p = 0.026). Both groups increased fat-free mass (p = 0.001); however, the increases were greater with NOSS (p = 0.023). NOSS underwent greater increases in upper-body (p = 0.023) and lower-body (p = 0.035) strength than CARB. Myofibrillar protein significantly increased in both groups (p = 0.041), with NOSS being greater than CARB (p = 0.049). All of the MHC isoforms were significantly increased in both groups; however, NOSS was greater than CARB for MHC 1 (p = 0.013) and MHC 2A (p = 0.046). All of the myogenic regulatory factors were significantly increased in both groups; however, NOSS was greater than CARB for Myo-D (p = 0.038) and MRF-4 (p = 0.001). For the whole blood and serum clinical chemistry markers, all variables remained within normal clinical ranges. Conclusions Heavy resistance training for 28 days, with NO-Shotgun® and NO-Synthesize® ingested before and after exercise, respectively, significantly improved body composition and increased muscle mass and performance without abnormally impacting any of the clinical chemistry markers.

2011-01-01

352

78 FR 53494 - Dam Safety Modifications at Cherokee, Fort Loudoun, Tellico, and Watts Bar Dams  

Federal Register 2010, 2011, 2012, 2013

...TENNESSEE VALLEY AUTHORITY Dam Safety Modifications at Cherokee, Fort Loudoun, Tellico, and Watts Bar Dams AGENCY: Tennessee Valley Authority...environmental impact statement (EIS) for the dam safety modifications at Cherokee,...

2013-08-29

353

Achieving Journalistic Authority through Narrative.  

ERIC Educational Resources Information Center

|Examines how journalists use three narrative strategies (synecdoche, omission, and personalization) to assert their authority in their retellings of the John F. Kennedy assassination. Finds that, by giving themselves a central position within the story, journalists make the assassination story as much about American journalists as about Kennedy's…

Zelizer, Barbie

1990-01-01

354

Authorization recycling in RBAC systems  

Microsoft Academic Search

As distributed applications increase in size and complexity, tradi- tional authorization mechanisms based on a single policy decision point are increasingly fragile because this decision point represents a single point of failure and a performance bottleneck. Authoriza- tion recycling is one technique that has been used to address these challenges. This paper introduces and evaluates the mechanisms for autho- rization

Qiang Wei; Jason Crampton; Konstantin Beznosov; Matei Ripeanu

2008-01-01

355

PARTISAN CONFLICTS OVER PRESIDENTIAL AUTHORITY  

Microsoft Academic Search

A prevailing view in the legal and political science literature assumes that power holders seek to expand or contract their constitutional authority based on incentives that are intrinsic to the logic of the institutional offices they occupy. For instance, it is generally assumed that Presidents are empire builders who will almost always prefer maximum flexibility in shaping their policy objectives,

Jide Okechuku Nzelibe

2011-01-01

356

Regional Mobility Authorities in Texas  

Microsoft Academic Search

A regional mobility authority (RMA) is an innovative tool that brings transportation decisions to the local levels and provides local governments the opportunity to accelerate needed projects. An RMA improves mobility, enhances economic development, and provides potential revenue sources through designing, constructing, operating and maintaining tolled or non-tolled roadways, passenger and freight rail, airports, and pedestrian and bicycle facilities.

David L. Bruno; Charles R. Stevens

357

The Role of Faculty Authority.  

ERIC Educational Resources Information Center

|A strong trend toward a federated structure in colleges and universities is affectin g faculty authority by weakening faculty as a whole and strengthening the faculty in its many parts. The collection of professional experts on one campus represents a system of groups with similar status and power that coexist or battle with each other within the…

Clark, Burton R.

358

A Virtual International Authority File.  

ERIC Educational Resources Information Center

|A pool of authority records for bibliographic entities (persons, corporate bodies, works/expressions, concepts, objects, events, and places) to use on the Internet is of interest, not only to libraries and their users, but also to publishers, copyright and rights management organizations, museums, and archives. This paper explores different…

Tillett, Barbara B.

359

Misconduct by researchers and authors  

Microsoft Academic Search

Most scientific research is conducted properly and reported honestly but a few authors invent or manipulate data to reach fraudulent conclusions. Other types of misconduct include deliberately providing incomplete or improperly processed data, failure to follow ethical procedures, failure to obtain informed consent, breach of patient confidentiality, improper award or denial of authorship, failure to declare competing interests, duplicate submission

Harvey Marcovitch

2007-01-01

360

Author Identification using Stylometric Features  

Microsoft Academic Search

In this work we present a strategy for author identification for documents written in Portuguese. It takes into account a writer-independent model which reduces the pattern recognition problem to a single model and two classes, hence, makes it possible to build robust system even when few genuine samples per writer are available. We also introduce a stylometric feature set, which

Daniel Pavelec; Edson J. R. Justino; Luiz S. Oliveira

2007-01-01

361

Food safety regulation and the firm: understanding the compliance process 1 Financial support from the Ministry of Agriculture, Fisheries and Food (MAFF) is acknowledged. However, the views expressed in this paper reflect those of the author and not necessarily those of MAFF. 1  

Microsoft Academic Search

An understanding of the process by which businesses comply with legal requirements is an essential, although frequently ignored, aspect of food safety regulation. The process of compliance is investigated through a postal survey and in-depth interviews with technical directors in a cross-section of food manufacturers and retailers in the UK. Although there are differences in the specific manner in which

Spencer Henson; Michael Heasman

1998-01-01

362

Workplace Safety and Health Topics: Safety & Prevention  

MedlinePLUS

... About CDC.gov . NIOSH Home Workplace Safety & Health Topics NIOSH NIOSH A-Z Index What's New on ... New Archive 1996-1997 Workplace Safety and Health Topics Industries & Occupations Hazards & Exposures Diseases & Injuries Safety & Prevention ...

363

Safety harness  

DOEpatents

A safety harness to be worn by a worker, especially a worker wearing a plastic suit thereunder for protection in a radioactive or chemically hostile environment, which safety harness comprises a torso surrounding portion with at least one horizontal strap for adjustably securing the harness about the torso, two vertical shoulder straps with rings just forward of the of the peak of the shoulders for attaching a life-line and a pair of adjustable leg supporting straps releasibly attachable to the torso surrounding portion. In the event of a fall, the weight of the worker, when his fall is broken and he is suspended from the rings with his body angled slightly back and chest up, will be borne by the portion of the leg straps behind his buttocks rather than between his legs. Furthermore, the supporting straps do not restrict the air supplied through hoses into his suit when so suspended.

Gunter, Larry W. (615 Sand Pit Rd., Leesville, SC 29070)

1993-01-01

364

Safety harness  

DOEpatents

A safety harness to be worn by a worker, especially a worker wearing a plastic suit thereunder for protection in a radioactive or chemically hostile environment. The safety harness comprises a torso surrounding portion with at least one horizontal strap for adjustably securing the harness about the torso, two vertical shoulder straps with rings just forward of the of the peak of the shoulders for attaching a life-line and a pair of adjustable leg supporting straps releasibly attachable to the torso surrounding portion. In the event of a fall, the weight of the worker, when his fall is broken and he is suspended from the rings with his body angled slightly back and chest up, will be borne by the portion of the leg straps behind his buttocks rather than between his legs. Furthermore, the supporting straps do not restrict the air supplied through hoses into his suit when so suspended.

Gunter, L.W.

1991-04-08

365

Biologics Post-Market Activities  

Center for Biologics Evaluation and Research (CBER)

... These post-market activities include lot release (for some products), post-marketing adverse event reporting, and post-marketing study ... More results from www.fda.gov/biologicsbloodvaccines/guidancecomplianceregulatoryinformation/post-marketactivities

366

14 CFR 431.71 - Public safety responsibility.  

Code of Federal Regulations, 2013 CFR

...ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING LAUNCH AND REENTRY OF A REUSABLE LAUNCH VEHICLE (RLV) Post-Licensing Requirements-Reusable Launch Vehicle Mission License Terms and Conditions § 431.71 Public safety...

2013-01-01

367

Drug Safety Information – FDA's Communication to the Public  

Center for Drug Evaluation (CDER)

Text Version... 8 8. What other Safety Information Does FDA Post on Its Web Site?....9 9. What Other Methods Are ... More results from www.fda.gov/downloads/drugs/guidancecomplianceregulatoryinformation

368

Food Safety  

Microsoft Academic Search

Food can never be entirely safe. Food safety is threatened by numerous pathogens that cause a variety of foodborne diseases,\\u000a algal toxins that cause mostly acute disease, and fungal toxins that may be acutely toxic but may also have chronic sequelae,\\u000a such as teratogenic, immunotoxic, nephrotoxic, and estrogenic effects. Perhaps more worrisome, the industrial activities of\\u000a the last century and

Andrea Borchers; Suzanne S. Teuber; Carl L. Keen; M. Eric Gershwin

2010-01-01

369

Designing Hypermedia Documentation for Safety Critical Applications  

Microsoft Academic Search

The paper discusses the requirements for authoring methodologies for large multimedia systems to be used for technical documentation in the domain of `safety critical' industries. In such industries the documentation used to support maintenance and repair may itself be safety critical, in that incorrect documentation can lead to incorrect maintenance procedures. Design issues for such systems include those of the

R. M. Newman; Coventry CV

2000-01-01

370

Occupational safety and health law handbook  

Microsoft Academic Search

This book reviews the regulations and standards governing the protection of employees in the workplace and provides insight into dealing with pertinent regulations and regulatory authorities. Written for safety professionals, industrial hygienists, human resource professionals, attorneys, and students, this companion to Government Institutes' best-selling ``Environmental Law Handbook'' offers the legal fundamentals behind occupational safety and health laws in one concise

D. G. Sarvadi

1999-01-01

371

Cultural Safety: Lessons from Maori Wisdom.  

ERIC Educational Resources Information Center

|Cultural safety has its current origins among the Maori peoples of New Zealand. The reader is encouraged to consider how rituals of encounter that promote cultural safety might enhance the cultural competence of workers and improve the quality of services offered in a variety of settings. (Author)|

Fulcher, Leon C.

2001-01-01

372

Good Practices Guide for Bicycle Safety Education.  

ERIC Educational Resources Information Center

|The purpose of this guide is to serve as an informational resource for educators and other interested professionals in planning and developing bicycle safety education programs. The guide examines 15 existing bicycle safety education programs in the United States and one from Canada. (Author)|

Department of Transportation, Washington, DC.

373

Computer-Aided Safety Interlock Systems.  

National Technical Information Service (NTIS)

Industrial process systems must be locked-out of disastrous operation modes. Here the problem of safety interlock system design is formulated in sequential logic and computer-aided interlock capability developed. (Author)

D. F. Rudd J. R. Rivas

1973-01-01

374

Elkhorn ruling boosts state authority  

SciTech Connect

On 31 May 1994, a landmark U.S. Supreme Court decision expanded state authority to establish conditions to protect water quality and included stream flows, aesthetics, and, potentially, other elements in a broad definition of water quality. Called the {open_quotes}Elkhorn case{close_quotes} the Supreme Court ruled that the state of Washington Department of Ecology has authority to set instream flows for fish (primarily steelhead, chinook, and coho salmon) as a condition of a Water Quality Certification (WQC) issued by the state under Section 401 of the federal Clean Water Act (CWA). The case surrounded the petitioners (applicants) proposed building of the Elkhorn Hydroelectric Project on the Dosewallips River, Washington. The project would have consisted of a dam near the boundary of Olympic National Park and a pipeline to carry diverted water around a 1.2-mile bypass reach to a powerhouse at Olympic National Forest`s Elkhorn Campground.

Beecher, H.A. [Washington Department of Fish and Wildlife, Olympia, WA (United States)

1995-03-01

375

[Amniotic band syndrome (author's transl)].  

PubMed

The authors present a critical revision of the literature concerning the pathogenic hypotheses and the opinions, during the centuries, about the origin of the deformities caused by amniotic bands. Here they describe two cases of severe deformities caused by amniotic bands which can be classified in types I and V according to Onnipoff and Hall. In the first case the newborn died immediately after the birth: the other one lives in good health after multiple surgical operations. In accordance with the anatomical reports that were found using very specific techniques and methods, the authors are inclined to accept Torpin's hypothesis, which affirms that the initial moment of the series of events which causes the formation of the amniotic bands is the breakage of the amniotic sac. PMID:7201131

Cagini, P; Barboni, G; Trabalza, N; Cappuccini, B; Perocchi, F; Vecchiarelli, G

376

FDA Drug Safety Newsletter  

Center for Drug Evaluation (CDER)

... Section Contents Menu. Drug Safety and Availability. FDA Drug Safety Newsletter. ... FDA Drug Safety Newsletter. The FDA Drug Safety ... More results from www.fda.gov/drugs/drugsafety/drugsafetynewsletter

377

Medical Device Safety  

MedlinePLUS

... Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Medical Devices Home Medical Devices Medical Device Safety - Section Contents ... Medical Product Safety Network Emergency Situations (Medical Devices) - Medical Device Safety Search the Medical Device Safety Section Medical ...

378

Strenghening Safeguards Authorities and Institutions  

SciTech Connect

The International Atomic Energy Agency (IAEA) safeguards system has changed in major ways from the establishment of the IAEA in 1957 until the present. Changes include strengthening the legal framework of safeguards; improvements in concepts and approaches for safeguards implementation; and significant improvements in the technical tools available to inspectors. In this paper, we explore three broad areas related to strengthening safeguards authorities and institutions: integrated safeguards and State-Level Approaches; special inspections; and NPT withdrawal and the continuation of safeguards.

Goodman,M.; Lockwood, d.; Rosenthal, M.D.; Tape, J.W.

2008-06-06

379

Electrical hot working safety program  

Microsoft Academic Search

An internal review of the safety practices for a large Canadian chemical plant indicated that the established procedures for electrical hot work needed to be expanded and formalized. Here, the authors describe how the practices were expanded into a comprehensive electrical hot work program that included a philosophy, controls, qualifications, and safe work methods. The program resulted in changes that

J. M. Gallagher; B. McClung

1996-01-01

380

PERSONAL SAFETY IN DANGEROUS PLACES  

Microsoft Academic Search

Personal safety during fieldwork is seldom addressed directly in the literature. Drawing from many prior years of ethnographic research and from field experience while studying crack distributors in New York City, the authors provide a variety of strategies by which ethnographic research can be safely conducted in dangerous settings. By projecting an appropriate demeanor, ethnographers can seek others for protector

TERRY WILLIAMS; ELOISE DUNLAP; BRUCE D. JOHNSON; ANSLEY HAMID

1992-01-01

381

Decreasing Ambiguity of the Safety Culture Concept  

SciTech Connect

The status of the concept of ''safety culture'' is reviewed. It has not sufficiently taken root. One cause for this is the abstract nature of the concept. Organizations must become aware of the necessity of improving safety and have sufficient power to promote this. The culture of safety must be instilled in each employee, so that each of them will feel responsible for identifying weak points in plant safety. The authors devised a tool for a self-assessment of the safety culture. The tool will bring to light information divides, communication gaps, etc. Recognizing the vulnerabilities of the organization by themselves and discussing these weak points among them is the first step to decrease the ambiguity of the safety culture. The next step is to make these gaps known along with agreed-upon countermeasures. The concept of safety culture will be greatly clarified in this way and lead to safer nuclear power plants.

Inoue, Shiichiro; Hosoda, Satoshi; Suganuma, Takashi; Monta, Kazuo; Kameda, Akiyuki

2001-06-17

382

9 CFR 592.10 - Authority.  

Code of Federal Regulations, 2013 CFR

...10 Section 592.10 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ...spirit and intent of the regulations in this part. The Food Safety Inspection Service and its officers and employees...

2013-01-01

383

47 CFR 80.1103 - Equipment authorization.  

Code of Federal Regulations, 2012 CFR

... FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS) Equipment Requirements for Ship Stations § 80.1103 Equipment...

2012-10-01

384

47 CFR 80.1103 - Equipment authorization.  

Code of Federal Regulations, 2011 CFR

... FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS) Equipment Requirements for Ship Stations § 80.1103 Equipment...

2011-10-01

385

40 CFR 761.30 - Authorizations.  

Code of Federal Regulations, 2013 CFR

...at a concentration level of Hydraulic systems that were in operation after...concentration level of Hydraulic systems may only be serviced with fluids...fence posts, sign posts, or bridge supports), as temporary flume at...

2013-07-01

386

Scope on Safety: Proactive safety  

NSDL National Science Digital Library

Horrifying stories of accidents in the science lab abound. You may think that such accidents could never happen in your lab, but accidents do happen even in the most controlled environments. So, the best thing you can do to protect yourselves and your students is to implement and document proactive safety procedures. The following actions are recommended to reduce accidents in the lab and litigation in the courtroom.

Roy, Ken

2006-09-01

387

43 CFR 11.90 - What documentation must the authorized official prepare after completing the assessment?  

Code of Federal Regulations, 2012 CFR

...the assessment? 11.90 Section 11.90 Public Lands: Interior Office of the Secretary of the Interior NATURAL RESOURCE DAMAGE ASSESSMENTS Post-Assessment Phase § 11.90 What documentation must the authorized official...

2012-10-01

388

43 CFR 11.90 - What documentation must the authorized official prepare after completing the assessment?  

Code of Federal Regulations, 2011 CFR

...the assessment? 11.90 Section 11.90 Public Lands: Interior Office of the Secretary of the Interior NATURAL RESOURCE DAMAGE ASSESSMENTS Post-Assessment Phase § 11.90 What documentation must the authorized official...

2011-10-01

389

76 FR 47197 - Authorization of Emergency Use of Oral Formulations of Doxycycline; Availability  

Federal Register 2010, 2011, 2012, 2013

...doxycycline for the post-exposure prophylaxis of inhalational anthrax during a public health emergency involving aerosolized Bacillus anthracis (B. anthracis). FDA is issuing this Authorization under the Federal Food, Drug, and Cosmetic Act (the...

2011-08-04

390

Diplomatic and Consular Immunity: Guidance for Law Enforcement and Judicial Authorities.  

National Technical Information Service (NTIS)

International Law, To Which The United States is firmly committed, requires that law enforcement authorities of the United States extend certain privileges and immunities to members of foreign diplomatic missions and consular posts. Most of these privileg...

1998-01-01

391

Post-Keynesian Theory: An Overview.  

ERIC Educational Resources Information Center

|The evolution and current position of post-Keynesian economic theory are examined. The theory is based on Keynes' exposition of effective demand in a monetary production economy determining the level of employment, rather than through supply and demand in the "real" and "monetary" sectors determining the level of real output. (Author/RM)|

Kregel, J. A.

1983-01-01

392

PostDoctoral Social Work Practice Experience  

Microsoft Academic Search

The authors of this article conducted a survey among all faculty members who had been hired within the past five years in colleges, schools or departments of social work among the Big Ten Universities. The aim was to determine the value and relevance of post-doctoral non-academic experience in academic settings as measured by faculty salary and rank. Results from this

Carla M. Curtis; Maria Julia

1996-01-01

393

Post-Error Adjustments  

PubMed Central

When our brain detects an error, this process changes how we react on ensuing trials. People show post-error adaptations, potentially to improve their performance in the near future. At least three types of behavioral post-error adjustments have been observed. These are post-error slowing (PES), post-error reduction of interference, and post-error improvement in accuracy (PIA). Apart from these behavioral changes, post-error adaptations have also been observed on a neuronal level with functional magnetic resonance imaging and electroencephalography. Neuronal post-error adaptations comprise activity increase in task-relevant brain areas, activity decrease in distracter-encoding brain areas, activity modulations in the motor system, and mid-frontal theta power increases. Here, we review the current literature with respect to these post-error adjustments, discuss under which circumstances these adjustments can be observed, and whether the different types of adjustments are linked to each other. We also evaluate different approaches for explaining the functional role of PES. In addition, we report reanalyzed and follow-up data from a flanker task and a moving dots interference task showing (1) that PES and PIA are not necessarily correlated, (2) that PES depends on the response–stimulus interval, and (3) that PES is reliable on a within-subject level over periods as long as several months.

Danielmeier, Claudia; Ullsperger, Markus

2011-01-01

394

Post-abortion mania.  

PubMed

We describe case histories of three women with post-abortion mania, including two women who underwent a change in diagnosis from bipolar II to bipolar I disorder and another woman who had no prior history of psychiatric disturbance. It is argued that the study of post-abortion mania should provide an opportunity to better understand the aetiology of puerperal mania. PMID:23381493

Sharma, Verinder; Sommerdyk, Christina; Sharma, Sapna

2013-02-05

395

10 CFR 63.31 - Construction authorization.  

Code of Federal Regulations, 2010 CFR

...Authorization § 63.31 Construction authorization. On...Commission may authorize construction of a geologic repository...part; (iii) DOE's quality assurance program complies...for is the issuance of the construction authorization, with...

2013-01-01

396

48 CFR 2805.502 - Authority.  

Code of Federal Regulations, 2011 CFR

...6 2011-10-01 2011-10-01 false Authority. 2805.502 Section...Authority. (a) Authorization for paid advertising is required for newspapers only... (b) Authority to purchase paid advertising must be granted in writing by an...

2011-10-01

397

1 CFR 21.45 - Nonstatutory authority.  

Code of Federal Regulations, 2012 CFR

...OF DOCUMENTS SUBJECT TO CODIFICATION Citations of Authority Placement § 21.45 Nonstatutory authority. Citation to a nonstatutory document as authority shall be placed after the statutory citations. For example: Authority:...

2012-01-01

398

1 CFR 21.45 - Nonstatutory authority.  

Code of Federal Regulations, 2013 CFR

...OF DOCUMENTS SUBJECT TO CODIFICATION Citations of Authority Placement § 21.45 Nonstatutory authority. Citation to a nonstatutory document as authority shall be placed after the statutory citations. For example: Authority:...

2013-01-01

399

14 CFR 1203b.103 - Arrest authority.  

Code of Federal Regulations, 2013 CFR

...ARREST AUTHORITY AND USE OF FORCE BY NASA SECURITY FORCE PERSONNEL § 1203b.103 Arrest authority. (a) NASA security force personnel may exercise...arrest authority. (b) The authority of NASA security force personnel to make a...

2013-01-01

400

Safety design of prototype fast breeder reactor  

SciTech Connect

The basic design and safety design of Prototype Fast Breeder Reactor (PFBR) is presented. Design aspects covered include safety classification, seismic categorization, design basis conditions, design safety limits, core physics, core monitoring, shutdown system, decay heat removal system, protection against sodium leaks and tube leaks in steam generator, plant layout, radiation protection, event analysis, beyond design basis accidents, integrity of primary containment, reactor containment building and design pressure resulting from core disruptive accident. The measures provided in the design represent a robust case of the safety of the reactor. (authors)

Bhoje, S.B.; Chetal, S.C.; Singh, Om Pal [Indira Gandhi Centre for Atomic Research, Kalpakkam (India)

2004-07-01

401

National Awareness Initiative: The School Safety Report Card.  

ERIC Educational Resources Information Center

The School Safety Report Card is a promising awareness initiative on the World Wide Web that surveys stakeholders about school-safety issues. Results are confidential and anonymous and will be posted on the web. The model outlines the conceptual, behavioral, and psychological components for identifying and helping at-risk students. (MLH)

Wilen, Saul B.; Fagan, Ruth N.; Van Wert, Frederick

2001-01-01

402

Epidemiological designs for vaccine safety assessment: Methods and pitfalls  

Microsoft Academic Search

Three commonly used designs for vaccine safety assessment post licensure are cohort, case-control and self-controlled case series. These methods are often used with routine health databases and immunisation registries. This paper considers the issues that may arise when designing an epidemiological study, such as understanding the vaccine safety question, case definition and finding, limitations of data sources, uncontrolled confounding, and

Nick Andrews

403

Safety alert for fentanyl buccal tablets.  

PubMed

On September 13, 2007, the United States Food and Drug Administration posted a safety alert for fentanyl buccal tablets (Fentora). The announcement and hyperlinks to the Dear Doctor and Dear Healthcare Professional Letters that were distributed by the sponsor are presented. PMID:19062355

2008-01-01

404

National Authority for Health: France.  

PubMed

The French National Authority for Health (Haute Autorité de Santé, or HAS) was established to assist France's public institutions in optimizing the basket of reimbursable goods and services and to help health care professionals continuously improve their clinical practice by defining best-care standards and identifying relevant tools and methods. HAS carries out single technology assessment (STA) and multiple technology assessment (MTA), assessing both the intrinsic benefit of the new technology and its effectiveness compared with that of existing technologies. A new treatment may not be covered unless it provides either improved benefit or lower cost, and STA is mandatory before a new drug, device, or medical procedure can be added to the benefit list for sickness funds. While HAS recommendations are advisory, the decision-making bodies (the Ministry of Health or the union of sickness funds) accept its findings in most cases. PMID:19639712

Rochaix, Lise; Xerri, Bertrand

2009-07-01

405

Misconduct by researchers and authors.  

PubMed

Most scientific research is conducted properly and reported honestly but a few authors invent or manipulate data to reach fraudulent conclusions. Other types of misconduct include deliberately providing incomplete or improperly processed data, failure to follow ethical procedures, failure to obtain informed consent, breach of patient confidentiality, improper award or denial of authorship, failure to declare competing interests, duplicate submission and plagiarism. Editors, peer reviewers and publishers may also act wrongly. Good practice guidelines are available from the International Committee of Medical Journal Editors (The Vancouver Group) and the Council of Science Editors, amongst others. The Committee on Publication Ethics provides flowcharts to assist editors deal with authorial misconduct. Examples are provided of cases involving epidemiological or public health research, reported to COPE over the last 9 years. Suggestions are offered as to how misconduct might be handled in future. PMID:18001665

Marcovitch, Harvey

406

Product Safety: Liability, R&D, and Signaling  

Microsoft Academic Search

The authors develop a monopoly model of product design and safety signaling incorporating a parametric liability specification. The firm first engages in R&D to affect the safety of its product. Since the outcome of R&D trials is unobservable to consumers, the firm then chooses its price, understanding that consumers may draw inferences from the price about the product's safety. Consumers

Andrew F Daughety; Jennifer F Reinganum

1995-01-01

407

A safety-focused verification using software fault trees  

Microsoft Academic Search

When developing safety-critical software such as reactor protection systems (RPS) in nuclear power plants, a demonstration of software trust (e.g., safety) is not only absolutely essential but also usually mandated by government authorities. While automated generation of fault trees has become possible with increased use of formal specifications, industrial use of fault trees has been limited primarily to safety demonstrations

Sungdeok Cha; Junbeom Yoo

408

Highway Safety Program Manual: Volume 15: Police Traffic Services.  

ERIC Educational Resources Information Center

|Volume 15 of the 19-volume Highway Safety Program Manual (which provides guidance to State and local governments on preferred highway safety practices) focuses on police traffic services. The purpose and objectives of a police services program are described. Federal authority in the areas of highway safety and policies regarding a police traffic…

National Highway Traffic Safety Administration (DOT), Washington, DC.

409

Ship Inspection Strategies: Effects on Maritime Safety and Environmental Protection  

Microsoft Academic Search

Global trade depends for a large part on maritime transport, and safe ships are needed not only to protect precious cargo but also to prevent environmental damage. Flag state and port state authorities spend much effort in ship safety inspections to ensure a minimum safety level and to prevent casualties. This paper investigates the safety gains of current inspection rules

C. Heij; G. E. Bijwaard; S. Knapp

2010-01-01

410

Age, Trust, and Perceived Safety from Crime in Rural Areas.  

ERIC Educational Resources Information Center

Examined the relationship of age and trust to perceived safety from crime among 891 rural residents from a statewide victim study. Trust was found to be a more important predictor of perceived safety than age, isolation, and income. Age had a direct, independent effect on perceived safety. (Author/NRB)

Mullen, Robert E.; Donnermeyer, Joseph F.

1985-01-01

411

[An analysis of appeals against the ruling of the occupational physician's lodged to the Department of Prevention and Safety in the Working Environment--Health Prevention and Occupational Epidemiology Operative Unit within the A.S.P. Palermo (Palermo Health Authority), years 2008-2010].  

PubMed

The purpose of this study is to analyze the appeals against a "suitability judgment for work" lodged to the U.O.S. "Health Prevention and Occupational Epidemiology Operative Unit" of Department of Prevention and Safety in the Working Environment within the ASP Palermo (U.O.S.), from 2008 to 2010. Studying the appeals gives an indirect view on the occupational physician activity and allows to monitor their actions, analysis aims at highlighting those issues around which any planning and implementation of coordination activities should be focused. PMID:23405625

Marsala, M G L; Morici, M; Lacca, G; Curcurů, L; Eduardo, E Costagliola; Ilardo, S; Trapani, E; Caracausi, R; Firenze, A

412

Delivering safety  

Microsoft Academic Search

In the United Kingdom there have been significant recent changes to the management of civil nuclear liabilities. With the formation in April 2005 of the Nuclear Decommissioning Authority (NDA), ownership of the civil nuclear licensed sites in the UK, including the Magnox Reactor Stations, passed to this new organisation. The NDAs mission is to seek acceleration of the nuclear clean

N. D. Baldwin; K. G. Spooner; P. Walkden

2007-01-01

413

Strain balanced quantum posts  

SciTech Connect

Quantum posts are assembled by epitaxial growth of closely spaced quantum dot layers, modulating the composition of a semiconductor alloy, typically InGaAs. In contrast with most self-assembled nanostructures, the height of quantum posts can be controlled with nanometer precision, up to a maximum value limited by the accumulated stress due to the lattice mismatch. Here, we present a strain compensation technique based on the controlled incorporation of phosphorous, which substantially increases the maximum attainable quantum post height. The luminescence from the resulting nanostructures presents giant linear polarization anisotropy.

Alonso-Alvarez, D.; Alen, B.; Ripalda, J. M.; Llorens, J. M.; Taboada, A. G.; Briones, F. [IMM-Instituto de Microelectronica de Madrid (CNM-CSIC), Isaac Newton 8, 28760 Tres Cantos (Spain); Roldan, M. A.; Hernandez-Saz, J.; Hernandez-Maldonado, D.; Herrera, M.; Molina, S. I. [Departamento de Ciencia de los Materiales e Ing. Metalurgica y Q. I., Universidad de Cadiz, Campus Universitario de Puerto Real, 11510 Puerto Real, Cadiz (Spain)

2011-04-25

414

42 CFR 1005.19 - Post-hearing briefs.  

Code of Federal Regulations, 2011 CFR

...OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OIG AUTHORITIES APPEALS OF EXCLUSIONS, CIVIL MONEY PENALTIES AND ASSESSMENTS § 1005.19 Post-hearing briefs. The ALJ may require the parties to file post-hearing...

2011-10-01

415

An Unusual Etiology of Post-traumatic Meningitis.  

PubMed

: Clostridium perfringens and related species are well-known culprits of post-traumatic soft tissue and bone infection. However, central nervous system involvement with these organisms spontaneously or subsequent to trauma is unusual. The authors reported a case of post-traumatic meningitis in which both C perfringens and Enterococcus faecium were isolated. PMID:23588266

Griffin, Allen T; Arnold, Forest W

2013-10-01

416

Safety Evaluation Report of the Waste Isolation Pilot Plant Contact Handled (CH) Waste Documented Safety Analysis  

Microsoft Academic Search

This Safety Evaluation Report (SER) documents the Department of Energyâs (DOE's) review of Revision 9 of the Waste Isolation Pilot Plant Contact Handled (CH) Waste Documented Safety Analysis, DOE\\/WIPP-95-2065 (WIPP CH DSA), and provides the DOE Approval Authority with the basis for approving the document. It concludes that the safety basis documented in the WIPP CH DSA is comprehensive, correct,

2005-01-01

417

Gardasil® Post-licensure Pediatric Safety and Adverse Event ...  

Center for Biologics Evaluation and Research (CBER)

Text Version... 142 Yes Erythema 134 Yes Vomiting 134 Yes Injection site pain 131 Yes Fall 124 Syncope sometimes resulting in falling with injury 12 Page 13. ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

418

40 CFR 170.235 - Posted pesticide safety information.  

Code of Federal Regulations, 2013 CFR

...the establishment or a restricted-entry interval has been in effect, the handler employer shall display, in accordance with...displayed in a central location on the farm or in the nursery or greenhouse where it can be readily seen and read by handlers....

2013-07-01

419

40 CFR 170.135 - Posted pesticide safety information.  

Code of Federal Regulations, 2013 CFR

...the establishment or a restricted-entry interval has been in effect, the agricultural employer shall display, in accordance...displayed in a central location on the farm or in the nursery or greenhouse where it can be readily seen and read by workers....

2013-07-01

420

FDA Drug Safety Communication: FDA requires post-market ...  

Center for Drug Evaluation (CDER)

... Drug Administration (FDA) is requiring the manufacturers of LABAs to conduct five randomized, double-blind, controlled clinical trials comparing the ... More results from www.fda.gov/drugs/drugsafety

421

Review of CBER's Current and Planned Post-marketing Safety ...  

Center for Biologics Evaluation and Research (CBER)

Text Version... s es a nd a na ly s is too ls FDA / CBER us es fo r id ent ifying sa fet ys ig na ls fo r CBER r eg u la t ed pr oducts in FDA s po nt a neo usr epo rt ing ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

422

Safety training methods  

Microsoft Academic Search

The book provides information necessary for the design, implementation and monitoring of occupational safety training programs. The place of the safety training program within a company is discussed, and the practical aspects of safety and health training programs are considered. OSHA safety and health training requirements are examined, together with the role of the supervisor in safety training and means

J. B. Revelle

1980-01-01

423

Rebuilding a safety culture  

NASA Astrophysics Data System (ADS)

The development of a culture of safety and NASA since the Challenger accident is reviewed. The technical elements of the strengthened NASA safety program are described, including problem reporting, risk/assessment/risk management, operational safety, and safety assurance are addressed. Future directions in the development of safety are considered.

Rodney, George A.

1991-11-01

424

Post-Polio Syndrome  

MedlinePLUS

... for post-polio syndrome. Causes CLICK TO ENLARGE Nerve cell (neuron) Nobody knows exactly what causes the signs ... polio syndrome rests on the idea of degenerating nerve cells. When poliovirus infects your body, it affects nerve ...

425

Evaluation of Hepatitis A Vaccine in Post-Exposure Prophylaxis, The Netherlands, 2004-2012  

PubMed Central

Background The secondary attack rate of hepatitis A virus (HAV) among contacts of cases is up to 50%. Historically, contacts were offered immunoglobulin (IG, a human derived blood product) as post-exposure prophylaxis (PEP). Amid safety concerns about IG, HAV vaccine is increasingly recommended instead. Public health authorities’ recommendations differ, particularly for healthy contacts ?40 years old, where vaccine efficacy data is limited. We evaluated routine use of HAV vaccine as an alternative to immunoglobulin in PEP, in those considered at low risk of severe infection in the Netherlands. Methods Household contacts of acute HAV cases notified in Amsterdam (2004-2012) were invited ?14 days post-exposure, for baseline anti-HAV testing and PEP according to national guidelines: immunoglobulin if at risk of severe infection, or hepatitis A vaccine if healthy and at low risk (aged <30, or, 30-50 years and vaccinated <8 days post-exposure). Incidence of laboratory confirmed secondary infection in susceptible contacts was assessed 4-8 weeks post-exposure. In a vaccinated subgroup, relative risk (RR) of secondary infection with estimated using Poisson regression. Results Of 547 contacts identified, 191 were susceptible to HAV. Per-protocol, 167 (87%) were vaccinated (mean:6.7 days post-exposure, standard deviation(sd)=3.3) and 24 (13%) were given immunoglobulin (mean:9.7 days post-exposure, sd=2.8). At follow-up testing, 8/112 (7%) had a laboratory confirmed infection of whom 7 were symptomatic. All secondary infections occurred in vaccinated contacts, and half were >40 years of age. In healthy contacts vaccinated per-protocol ?8 days post-exposure, RRref. ?15 years of secondary infection in those >40 years was 12.0 (95%CI:1.3-106.7). Conclusions Timely administration of HAV vaccine in PEP was feasible and the secondary attack rate was low in those <40 years. Internationally, upper age-limits for post-exposure vaccination vary. Pending larger studies, immunoglobulin should be considered PEP of choice in people >40 years of age and those vulnerable to severe disease.

Whelan, Jane; Sonder, Gerard J.; Bovee, Lian; Speksnijder, Arjen; van den Hoek, Anneke

2013-01-01

426

A comparison of commercial/industry and nuclear weapons safety concepts  

SciTech Connect

In this paper the authors identify factors which influence the safety philosophy used in the US commercial/industrial sector and compare them against those factors which influence nuclear weapons safety. Commercial/industrial safety is guided by private and public safety standards. Generally, private safety standards tend to emphasize product reliability issues while public (i.e., government) safety standards tend to emphasize human factors issues. Safety in the nuclear weapons arena is driven by federal requirements and memoranda of understanding (MOUs) between the Departments of Defense and Energy. Safety is achieved through passive design features integrated into the nuclear weapon. Though the common strand between commercial/industrial and nuclear weapons safety is the minimization of risk posed to the general population (i.e., public safety), the authors found that each sector tends to employ a different safety approach to view and resolve high-consequence safety issues.

Bennett, R.R.; Summers, D.A.

1996-07-01

427

Safety evaluation for packaging CPC metal boxes  

Microsoft Academic Search

This Safety Evaluation for Packaging (SEP) provides authorization for the use of Container Products Corporation (CPC) metal boxes, as described in this document, for the interarea shipment of radioactive contaminated equipment and debris for storage in the Central Waste Complex (CWC) or T Plant located in the 200 West Area. Authorization is granted until November 30, 1995. The CPC boxes

1995-01-01

428

48 CFR 23.402 - Authorities.  

Code of Federal Regulations, 2012 CFR

...REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE...2007, Strengthening Federal Environmental, Energy, and Transportation Management. (d)...

2012-10-01

429

International Peer Review of FSANZ GM Food Safety Assessment Process  

Microsoft Academic Search

FSANZ has established itself internationally as one of the leading regulatory authorities to regulate and conduct safety assessment of Genetically Modified (GM) foods. A small but knowledgeable, dedicated team of scientists in the Risk Assessment Chemical Safety Section and Product Safety Standards Section of FSANZ routinely conduct robust, risk-based and evidence-based pre-market safety assessment of GM foods. FSANZ has also

William Yan

430

77 FR 41190 - Revised Document Posted: NIOSH List of Antineoplastic and Other Hazardous Drugs in Healthcare...  

Federal Register 2010, 2011, 2012, 2013

...SERVICES Centers for Disease Control and Prevention [Docket Number NIOSH-190] Revised Document Posted: NIOSH List of Antineoplastic and Other Hazardous Drugs in Healthcare Settings 2012, Correction AGENCY: National Institute for Occupational Safety...

2012-07-12

431

A comparison of commercial\\/industry and nuclear weapons safety concepts  

Microsoft Academic Search

In this paper the authors identify factors which influence the safety philosophy used in the US commercial\\/industrial sector and compare them against those factors which influence nuclear weapons safety. Commercial\\/industrial safety is guided by private and public safety standards. Generally, private safety standards tend to emphasize product reliability issues while public (i.e., government) safety standards tend to emphasize human factors

R. R. Bennett; D. A. Summers

1996-01-01

432

Autonomous Flight Safety System.  

National Technical Information Service (NTIS)

Autonomous Flight Safety System (AFSS) is an independent flight safety system designed for small to medium sized expendable launch vehicles launching from or needing range safety protection while overlying relatively remote locations. AFSS replaces the ne...

B. Bull B. Ferrell J. Lanzi J. Simpson R. Zoerner S. Santuro

2004-01-01

433

National Safety Council  

MedlinePLUS

... Safety Council recognizes 2013 Class of NSC Rising Stars of Safety at its Congress & Expo The Council recognizes its latest class of NSC Rising Stars of Safety, in conjunction with its 2013 NSC ...

434

Project Nuclear Safety (PNS).  

National Technical Information Service (NTIS)

The annual report of the nuclear safety project (PNS) describes the work of the participating institutes in the fields of 1) safety and environmental protection in nuclear power plants, 2) safety and environmental protection in reprocessing plants, and 3)...

1978-01-01

435

Water Safety Lesson  

NSDL National Science Digital Library

Through role-playing and teacher presentation, students learn how to be safe around water. Students learn the three most important safety rules, ways to rescue someone from the water, boat safety, and ocean safety considerations.

Diego, The C.

2010-04-12

436

WashingtonPost.com WeatherPost  

NSDL National Science Digital Library

The Washington Post makes a bid for the already crowded Internet weather market with WeatherPost. Coverage includes current conditions and four-day forecasts for 3,600 cities worldwide, as well as snapshot and time-lapse satellite maps (provided by Accu Weather). For US cities, users may also access UV and air quality maps and data, as well as seasonal maps (snow cover, tanning index, heat index, and BeachCast) and other radar images such as precipitation. Users may enter a city name into the homepage search box, or may browse by country or state/province. The historical weather database offers compiled monthly average weather data for nearly 1,000 cities worldwide; the database is searchable. An aspect of the site that sets it apart from many other weather pages is the weather reference desk, which includes a weather glossary, weather calculators (JavaScript converters for temperature, wind chill, heat index, etc.) and a page devoted to storm chasers.

1997-01-01

437

The application of post-market monitoring to novel foods  

Microsoft Academic Search

The role of post-market monitoring (PMM) in the safety assessment of novel foods is critically discussed in order to derive guidelines as to in which situations the application of PMM might be warranted. Available data sources on food consumption and health status, and the methodologies for generating such data are reviewed. The paper suggests improvements to make them more applicable

P. Hepburn; J. Howlett; H. Boeing; A. Cockburn; A. Constable; A. Davi; N. de Jong; B. Moseley; R. Oberdörfer; C. Robertson; J. M. Wal; F. Samuels

2008-01-01

438

10 CFR 26.55 - Initial authorization.  

Code of Federal Regulations, 2013 CFR

...2013-01-01 2013-01-01 false Initial authorization. 26.55 Section 26.55 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Granting and Maintaining Authorization § 26.55 Initial authorization. (a) Before...

2013-01-01

439

10 CFR 26.71 - Maintaining authorization.  

Code of Federal Regulations, 2013 CFR

...2013-01-01 false Maintaining authorization. 26.71 Section 26.71 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Granting and Maintaining Authorization § 26.71 Maintaining authorization. (a)...

2013-01-01

440

10 CFR 26.59 - Authorization reinstatement.  

Code of Federal Regulations, 2013 CFR

...2013-01-01 false Authorization reinstatement. 26.59 Section 26.59 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Granting and Maintaining Authorization § 26.59 Authorization reinstatement. (a) In...

2013-01-01

441

15 CFR 4a.4 - Classification authority.  

Code of Federal Regulations, 2012 CFR

...Classification authority. Authority to originally classify information as Secret or Confidential may be exercised only by the Secretary of Commerce...Department is authorized to originally classify information as Top...

2012-01-01

442

14 CFR 183.49 - Authorized functions.  

Code of Federal Regulations, 2013 CFR

...2013-01-01 false Authorized functions. 183.49 Section 183.49 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION...ADMINISTRATOR Organization Designation Authorization § 183.49 Authorized functions. (a) Consistent with...

2013-01-01

443

10 CFR 60.31 - Construction authorization.  

Code of Federal Regulations, 2013 CFR

...2013-01-01 2013-01-01 false Construction authorization. 60.31 Section 60...WASTES IN GEOLOGIC REPOSITORIES Licenses Construction Authorization § 60.31 Construction authorization. Upon review and...

2013-01-01

444

48 CFR 2405.502 - Authority.  

Code of Federal Regulations, 2011 CFR

...PUBLICIZING CONTRACT ACTIONS Paid Advertisements 2405.502 Authority. Use of paid advertisements in newspapers, trade journals, and other media are authorized by Delegations or Redelegations of Authority, subject to the availability of funds....

2011-10-01

445

78 FR 4766 - Authority Citation Correction  

Federal Register 2010, 2011, 2012, 2013

...File No. S7-19-11] Authority Citation Correction AGENCY: Securities and Exchange...instruction pertaining to an authority citation. The Commission is publishing this technical...amendment to accurately reflect the authority citation in the Code of Federal...

2013-01-23

446

31 CFR 402.1 - Reproductions authorized.  

Code of Federal Regulations, 2010 CFR

...2009-07-01 2009-07-01 false Reproductions authorized. 402.1 Section...DEPARTMENT OF THE TREASURY REPRODUCTION OF CANCELED UNITED STATES INTERNAL REVENUE STAMPS § 402.1 Reproductions authorized. Authority...

2009-07-01

447

31 CFR 402.1 - Reproductions authorized.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Reproductions authorized. 402.1 Section...DEPARTMENT OF THE TREASURY REPRODUCTION OF CANCELED UNITED STATES INTERNAL REVENUE STAMPS § 402.1 Reproductions authorized. Authority...

2013-07-01

448

31 CFR 402.1 - Reproductions authorized.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Reproductions authorized. 402.1 Section...DEPARTMENT OF THE TREASURY REPRODUCTION OF CANCELED UNITED STATES INTERNAL REVENUE STAMPS § 402.1 Reproductions authorized. Authority...

2010-07-01

449

48 CFR 2805.502 - Authority.  

Code of Federal Regulations, 2012 CFR

...PUBLICIZING CONTRACT ACTIONS Paid Advertisements 2805.502 Authority. ...authority to approve publication of paid advertisements in newspapers has been delegated...official delegated such authority. No advertisement, notice, or proposal will be...

2012-10-01

450

48 CFR 1305.502 - Authority.  

Code of Federal Regulations, 2011 CFR

...ACQUISITION PLANNING PUBLICIZING CONTRACT ACTIONS Paid Advertisements 1305.502 Authority. The designee authorized to provide authorization for publication of paid advertisements in newspapers is set forth in CAM 1301.70. The...

2011-10-01

451

48 CFR 1305.502 - Authority.  

Code of Federal Regulations, 2012 CFR

...ACQUISITION PLANNING PUBLICIZING CONTRACT ACTIONS Paid Advertisements 1305.502 Authority. The designee authorized to provide authorization for publication of paid advertisements in newspapers is set forth in CAM 1301.70. The...

2012-10-01

452

48 CFR 405.502 - Authority.  

Code of Federal Regulations, 2012 CFR

...ACQUISITION PLANNING PUBLICIZING CONTRACT ACTIONS Paid Advertisements 405.502 Authority. (a) The authority vested in the agency head to authorize publication of paid advertisements in newspapers (44 U.S.C. 3702) is...

2012-10-01

453

47 CFR 24.131 - Authorized bandwidth.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 2011-10-01 false Authorized bandwidth. 24.131 Section 24.131 Telecommunication...SERVICES Narrowband PCS § 24.131 Authorized bandwidth. The authorized bandwidth of narrowband PCS channels will be 10...

2011-10-01

454

47 CFR 5.105 - Authorized bandwidth.  

Code of Federal Regulations, 2012 CFR

... 2012-10-01 false Authorized bandwidth. 5.105 Section 5.105 Telecommunication...Requirements § 5.105 Authorized bandwidth. Each authorization issued to...figure specifying the maximum necessary bandwidth for the emission used. The...

2012-10-01

455

47 CFR 24.131 - Authorized bandwidth.  

Code of Federal Regulations, 2012 CFR

...2012-10-01 2012-10-01 false Authorized bandwidth. 24.131 Section 24.131 Telecommunication...SERVICES Narrowband PCS § 24.131 Authorized bandwidth. The authorized bandwidth of narrowband PCS channels will be 10...

2012-10-01

456

46 CFR Sec. 21 - Delegations of authority.  

Code of Federal Regulations, 2012 CFR

...UNDER NATIONAL SHIPPING AUTHORITY MASTER LUMP SUM REPAIR CONTRACT-NSA-LUMPSUMREP Sec. 21 Delegations of authority. (a...Authority appears in several of the contract provisions of the NSA-LUMPSUMREP Contract. The respective representatives of...

2012-10-01

457

77 FR 26149 - Access Authorization Fees  

Federal Register 2010, 2011, 2012, 2013

...RIN 3150-AJ00 Access Authorization Fees AGENCY: Nuclear Regulatory Commission...amending the NRC's access authorization fees charged to licensees for work performed...authorization. The NRC's formula for calculating fees remains the same and is based on...

2012-05-03

458

Making Shop Safety Relevant to Occupational Safety  

ERIC Educational Resources Information Center

The McGuffey High School Vocational Agriculture Department, Claysville, Pennsylvania uses a shop safety demerit system, similar to those used in many industries, to relate safety to the real world of work. The system (context included) has proven effective in creating safety awareness. (EA)

Harshman, William C.

1974-01-01

459

Quality and safety aspects of infant nutrition.  

PubMed

Quality and safety aspects of infant nutrition are of key importance for child health, but oftentimes they do not get much attention by health care professionals whose interest tends to focus on functional benefits of early nutrition. Unbalanced diets and harmful food components induce particularly high risks for untoward effects in infants because of their rapid growth, high nutrient needs, and their typical dependence on only one or few foods during the first months of life. The concepts, standards and practices that relate to infant food quality and safety were discussed at a scientific workshop organized by the Child Health Foundation and the Early Nutrition Academy jointly with the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, and a summary is provided here. The participants reviewed past and current issues on quality and safety, the role of different stakeholders, and recommendations to avert future issues. It was concluded that a high level of quality and safety is currently achieved, but this is no reason for complacency. The food industry carries the primary responsibility for the safety and suitability of their products, including the quality of composition, raw materials and production processes. Introduction of new or modified products should be preceded by a thorough science based review of suitability and safety by an independent authority. Food safety events should be managed on an international basis. Global collaboration of food producers, food-safety authorities, paediatricians and scientists is needed to efficiently exchange information and to best protect public health. PMID:22699763

Koletzko, Berthold; Shamir, Raanan; Ashwell, Margaret

2012-06-06

460

Safety of Phenylpropanolamine  

Center for Drug Evaluation (CDER)

... Safety of Phenylpropanolamine. Food and Drug Administration Public Health Advisory Subject: Safety of Phenylpropanolamine. November 6, 2000. ... More results from www.fda.gov/drugs/drugsafety/postmarketdrugsafetyinformationforpatientsandproviders

461

Aristolochic Acid: Safety Alert  

Center for Food Safety and Applied Nutrition (CFSAN)

... Section Contents Menu. Recalls, Outbreaks & Emergencies. Safety Alerts & Advisories. -. Aristolochic Acid: Safety Alert. FDA ... More results from www.fda.gov/food/recallsoutbreaksemergencies/safetyalertsadvisories

462

National Ag Safety Database  

NSDL National Science Digital Library

A national central repository of agricultural health, safety, and injury prevention materials for the agricultural community and especially for agricultural safety specialists. Spanish materials are included.

2007-01-15

463

Farm Health and Safety  

MedlinePLUS

... jobs in the United States. Farms have many health and safety hazards, including Chemicals and pesticides Machinery, ... equipment can also reduce accidents. Occupational Safety and Health Administration

464

50 CFR 38.5 - Emergency authority.  

Code of Federal Regulations, 2012 CFR

...CONTINUED) THE NATIONAL WILDLIFE REFUGE SYSTEM MIDWAY ATOLL NATIONAL WILDLIFE REFUGE Executive Authority; Authorized...lawful acts necessary to protect life and property on Midway Atoll National Wildlife...

2012-10-01

465

50 CFR 38.5 - Emergency authority.  

Code of Federal Regulations, 2011 CFR

...CONTINUED) THE NATIONAL WILDLIFE REFUGE SYSTEM MIDWAY ATOLL NATIONAL WILDLIFE REFUGE Executive Authority; Authorized...lawful acts necessary to protect life and property on Midway Atoll National Wildlife...

2011-10-01

466

48 CFR 2001.102 - Authority.  

Code of Federal Regulations, 2011 CFR

... false Authority. 2001.102 Section 2001.102 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance...

2011-10-01

467

48 CFR 2001.102 - Authority.  

Code of Federal Regulations, 2012 CFR

... false Authority. 2001.102 Section 2001.102 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance...

2012-10-01

468

48 CFR 3405.502 - Authority.  

Code of Federal Regulations, 2012 CFR

...COMPETITION AND ACQUISITION PLANNING PUBLICIZING CONTRACT ACTIONS Paid Advertisements 3405.502 Authority. Authority to approve publication of paid advertisements in newspapers is delegated to the...

2012-10-01

469

Post-AGB Stars  

NASA Astrophysics Data System (ADS)

In this contribution, a review is presented on the ample data obtained on post-AGB stars, both on the central stars and their circumstellar material. The fast evolutionary phase is characterized by a rapid change in the properties of the objects, but the variety is so large that there is yet no clear consensus on how the detailed studies of individual objects are linked together by evolutionary channels. The absence of strong molecular veiling in the photospheres of the central stars, together with a spread in intrinsic metallicity make post-AGB stars very useful in constraining AGB chemical evolutionary models. We discuss the surprisingly wide variety of chemical signatures observed. The onset in the creation process of the panoply of structures and shapes observed in planetary nebulae occurs during the short post-AGB evolution, but the physical nature of the processes involved is still badly understood. In the rapidly growing field of circumstellar mineralogy, post-AGB stars have their story to tell and also the molecular envelope changes significantly due to dilution and hardening of the stellar radiation. The real-time evolution of some objects suffering a late thermal flash is reviewed and their possible link to other hydrogen-deficient objects is discussed. Any review on stellar evolution has a section on binaries and this contribution is no exception because binaries make up a significant fraction of the post-AGB stars known to date.

van Winckel, Hans

470

Food safety.  

PubMed

Food can never be entirely safe. Food safety is threatened by numerous pathogens that cause a variety of foodborne diseases, algal toxins that cause mostly acute disease, and fungal toxins that may be acutely toxic but may also have chronic sequelae, such as teratogenic, immunotoxic, nephrotoxic, and estrogenic effects. Perhaps more worrisome, the industrial activities of the last century and more have resulted in massive increases in our exposure to toxic metals such as lead, cadmium, mercury, and arsenic, which now are present in the entire food chain and exhibit various toxicities. Industrial processes also released chemicals that, although banned a long time ago, persist in the environment and contaminate our food. These include organochlorine compounds, such as 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (dichlorodiphenyl dichloroethene) (DDT), other pesticides, dioxins, and dioxin-like compounds. DDT and its breakdown product dichlorophenyl dichloroethylene affect the developing male and female reproductive organs. In addition, there is increasing evidence that they exhibit neurodevelopmental toxicities in human infants and children. They share this characteristic with the dioxins and dioxin-like compounds. Other food contaminants can arise from the treatment of animals with veterinary drugs or the spraying of food crops, which may leave residues. Among the pesticides applied to food crops, the organophosphates have been the focus of much regulatory attention because there is growing evidence that they, too, affect the developing brain. Numerous chemical contaminants are formed during the processing and cooking of foods. Many of them are known or suspected carcinogens. Other food contaminants leach from the packaging or storage containers. Examples that have garnered increasing attention in recent years are phthalates, which have been shown to induce malformations in the male reproductive system in laboratory animals, and bisphenol A, which negatively affects the development of the central nervous system and the male reproductive organs. Genetically modified foods present new challenges to regulatory agencies around the world because consumer fears that the possible health risks of these foods have not been allayed. An emerging threat to food safety possibly comes from the increasing use of nanomaterials, which are already used in packaging materials, even though their toxicity remains largely unexplored. Numerous scientific groups have underscored the importance of addressing this issue and developing the necessary tools for doing so. Governmental agencies such as the US Food and Drug Administration and other agencies in the USA and their counterparts in other nations have the increasingly difficult task of monitoring the food supply for these chemicals and determining the human health risks associated with exposure to these substances. The approach taken until recently focused on one chemical at a time and one exposure route (oral, inhalational, dermal) at a time. It is increasingly recognized, however, that many of the numerous chemicals we are exposed to everyday are ubiquitous, resulting in exposure from food, water, air, dust, and soil. In addition, many of these chemicals act on the same target tissue by similar mechanisms. "Mixture toxicology" is a rapidly growing science that addresses the complex interactions between chemicals and investigates the effects of cumulative exposure to such "common mechanism groups" of chemicals. It is to be hoped that this results in a deeper understanding of the risks we face from multiple concurrent exposures and makes our food supply safer. PMID:19911313

Borchers, Andrea; Teuber, Suzanne S; Keen, Carl L; Gershwin, M Eric

2010-10-01

471

Bromine Safety  

SciTech Connect

The production and handling in 1999 of about 200 million kilograms of bromine plus substantial derivatives thereof by Great Lakes Chemical Corp. and Albemarle Corporation in their southern Arkansas refineries gave OSHA Occupational Injury/Illness Rates (OIIR) in the range of 0.74 to 1.60 reportable OIIRs per 200,000 man hours. OIIRs for similar industries and a wide selection of other U.S. industries range from 1.6 to 23.9 in the most recent OSHA report. Occupational fatalities for the two companies in 1999 were zero compared to a range in the U.S.of zero for all computer manufacturing to 0.0445 percent for all of agriculture, forestry and fishing in the most recent OSHA report. These results show that bromine and its compounds can be considered as safe chemicals as a result of the bromine safety standards and practices at the two companies. The use of hydrobromic acid as an electrical energy storage medium in reversible PEM fuel cells is discussed. A study in 1979 of 20 megawatt halogen working fluid power plants by Oronzio de Nora Group found such energy to cost 2 to 2.5 times the prevailing base rate at that time. New conditions may reduce this relative cost. The energy storage aspect allows energy delivery at maximum demand times where the energy commands premium rates. The study also found marginal cost and performance advantages for hydrobromic acid over hydrochloric acid working fluid. Separate studies in the late 70s by General Electric also showed marginal performance advantages for hydrobromic acid.

Meyers, B

2001-04-09

472

Authenticity, Autonomy, and Authority: Feminist Jewish Learning among Post-Soviet Women  

ERIC Educational Resources Information Center

|This articles explores how a group of women in the Former Soviet Union grapple with questions of Jewish identity and Jewish "authenticity" as they participate in adult Jewish learning program that employs methods of feminist pedagogy and transformative learning. The study reflects on areas of dissonance between the transformational learning…

Grant, Lisa D.

2008-01-01

473

[Tubular permeability maintained in post-ischemic acute renal failure (author's transl)].  

PubMed

The effect of nearly total renal ischemia during a two hour period on glomerular filtration and urine composition was studied in relation to tubular permeability and tubular obstruction, two mechanisms that could explain renal insuficiency after iscehmia. Studies on creatinine clearance, micropuncture and microinjection of 14C-inulin into the proximal tubules by means of a hydraulic system were performed before and after the period of ischemia. Thirty minutes after the withdrawal of arterial obstruction, the animals exhibited a maintained diuresis, 50 per cent reduction in glomerular filtration in the superficial nephrons and in the total kidney, a reduction in the proximal fractional absorption of water, and also an increase in the urinary elimination of sodium. The glomerular filtrate of cortical nephorns obtained by micropuncture in anterior areas of the proximal tubules did not differ significantly from the one obtained by micropuncture in more distal areas. The inulin injected into the proximal tubules of a kidney was entirely eliminated by it. PMID:857278

López-Novoa, J M; Rengel, M A; Ortega, F J; Rodicio, J L; Hernando, L

1977-03-01

474

78 FR 60220 - Safety Zone; Fireworks Display, Willamette River, Oregon City, OR  

Federal Register 2010, 2011, 2012, 2013

The Coast Guard is establishing a safety zone in Oregon City, OR. This safety zone is necessary to help ensure the safety of the maritime public during a fireworks display and will do so by prohibiting unauthorized persons and vessels from entering the safety zones unless authorized by the Sector Columbia River Captain of the Port or his designated...

2013-10-01

475

Testing safety commitment in organizations through interpretations of safety artifacts  

Microsoft Academic Search

ProblemSafety culture relates to injuries and safety incidents in organizations, but is difficult to asses and measure. We describe a preliminary test of assessing an organization's safety culture by examining employee interpretations of organizational safety artifacts (safety signs).

Gil Luria; Anat Rafaeli

2008-01-01

476

Developing a culture of safety in the epilepsy monitoring unit: a retrospective study of safety outcomes.  

PubMed

This study retrospectively reviewed 971 consecutive admissions to our epilepsy monitoring unit (EMU) from July 2007 to May 2011 to compare falls and missed seizures before and after implementing stricter safety processes in May 2009. New safety processes included enhanced staff education, a falls prevention signed contract with patient/family, observation of video-EEG monitors only by EEG technologists, hourly nurse rounding, standby assistance for hygiene needs, and immediate review of adverse events. Wilcoxon's two-sample tests were used for statistical analysis of the two groups. Reduced events between pre-intervention (492 patients) and post-intervention (479 patients) were significant for missed seizures (26 pre- vs 6 post-intervention, p=0.009) but not for falls (12 pre- vs 7 post-intervention, p=0.694). Intensive safety efforts in the EMU produced a 15% reduction in the fall rate per 1000 patient days and a 77% decrease in missed seizures. This study shows stricter safety processes help improve EMU patient safety. PMID:23032129

Spanaki, Marianna V; McCloskey, Cathleen; Remedio, Virginia; Budzyn, D; Guanio, Joanne; Monroe, Traci; Barkley, Gregory L; Schultz, Lonni

2012-09-30

477

The Literary Life of Educational Authority  

ERIC Educational Resources Information Center

This article looks into the workings of educational authority. While scholarly debate in education usually promotes authority as either good or bad, the same debate seldom asks questions about how authority works. This article is, then, an answer to the question "How?" How does educational authority operate? It operates, it is suggested, in much…

Bingham, Charles

2006-01-01

478

Provision of information on regulatory authorities websites  

Microsoft Academic Search

Background: Several organizations have raised concerns about the excessive secrecy maintained by regulatory authorities around the world, in particular in the European Union, France, UK, Canada and Australia. However, limited research has assessed the provision of information by regulatory authorities. This study aimed to assess the type and availability of information provided on the regulatory authorities' websites. Methods: Regulatory authorities'

A. Vitry; J. Lexchin; L. Sasich; T. Dupin-Spriet; T. Reed; V. Bertele; S. Garattini; L. Toop; E. Hurley

2008-01-01

479

Authoring Intelligent Tutoring Systems for Disabled Learners  

Microsoft Academic Search

The purpose of this paper is to present an authoring tool for the development of a distance learning hypermedia intelligent tutoring system (HITS). Designed to satisfy guidelines of accessibility of the W3C recommendation for authors and learners that present disabilities, the authoring tool allows several authors geographically dispersed to cooperate to produce such tutors together. It consists of a shared

Said Talhi; Mahieddine Djoudi; Salima Ouadfel; Samir Zidat

480

An Authority Control Alternative for Small Colleges.  

ERIC Educational Resources Information Center

|Authority control improves users' access to a library's holdings by enhancing the ability to find and select materials. The AutoCat authority control system developed at Dickinson College (Carlisle, Pennsylvania) avoids the high initial costs of vendor clean up and Library of Congress authority tapes while reducing the labor involved in authority

Bechtel, Joan M.

1992-01-01

481

Post dryout heat transfer tests in a two-section heated tube  

Microsoft Academic Search

Experiments were carried out on a 4 m length of Inconel tube as part of the boiling water reactor safety studies program. Once dryout was established at the end of the first tube section, steady state post dryout measurements were made at several heat flux values over the second tube section. Transient dryout recovery from prefixed post dryout conditions over

G. Barzoni; G. P. Gaspari; R. Martini

1980-01-01

482

Safety: Preventive Medicine.  

ERIC Educational Resources Information Center

Underscores the need for community colleges to practice safety within the institutions and to instruct students in workplace safety procedures and requirements. Reviews Occupational Safety and Health Act (OSHA) regulations and their impact on industry and education. Looks at the legal responsibilities of colleges for safety. (DMM)

Kotula, John R.; Digenakis, Anthony

1985-01-01

483

Improving patient safety culture  

Microsoft Academic Search

Purpose – Improving hospital patient safety means an open and stimulating culture is needed. This article aims to describe a patient safety culture improvement approach in five Belgian hospitals. Design\\/methodology\\/approach – Patient safety culture was measured using a validated Belgian adaptation of the Hospital Survey on Patient Safety Culture (HSOPSC) questionnaire. Studies before (autumn 2005) and after (spring 2007) the

Johan Hellings; Ward Schrooten; Niek S. Klazinga; Arthur Vleugels

2010-01-01

484

Safety Standards for Projectors.  

ERIC Educational Resources Information Center

The safety of projectors and related viewing devices for school, home, and business use is of paramount importance. The Advisory Committee on Safety (ACOS) of the International Electrotechnical Commission (IEC) has established a working group to consider the problem of projector safety and to make recommendations for safety standards. (CMV)

Wyman, Raymond

1979-01-01

485

Safety class methodology  

Microsoft Academic Search

DOE Order 6430.1A, General Design Criteria (GDC), requires that DOE facilities be evaluated with respect to safety class items.'' Although the GDC defines safety class items, it does not provide a methodology for selecting safety class items. The methodology described in this paper was developed to assure that Safety Class Items at the Savannah River Site (SRS) are selected in

E. B. Donner; J. M. Low; C. R. Lux

1992-01-01

486

Safety class methodology  

Microsoft Academic Search

DOE Order 6430.1A, General Design Criteria (GDC), requires that DOE facilities be evaluated with respect to ``safety class items.`` Although the GDC defines safety class items, it does not provide a methodology for selecting safety class items. The methodology described in this paper was developed to assure that Safety Class Items at the Savannah River Site (SRS) are selected in

E. B. Donner; J. M. Low; C. R. Lux

1992-01-01

487

Reactor Safety Research Programs  

SciTech Connect

This document summarizes the work performed by Pacific Northwest laboratory from October 1 through December 31, 1979, for the Division of Reactor Safety Research within the Nuclear Regulatory Commission. Evaluation of nondestructive examination (NDE) techniques and instrumentation are reported; areas of investigation include demonstrating the feasibilty of determining structural graphite strength, evaluating the feasibilty of detecting and analyzing flaw growth in reactor pressure boundary systems, examining NDE reliability and probabilistic fracture mechanics, and assessing the remaining integrity of pressurized water reactor steam generator tubes where service-induced degradation has been indicated. Test assemblies and analytical support are being provided for experimental programs at other facilities. These programs include the loss-of-coolant accident simulation tests at the NRU reactor, Chalk River, Canada; the fuel rod deformation and post-accident coolability tests for the ESSOR Test Reactor Program, lspra, Italy; the blowdown and reflood tests in the test facility at Cadarache, France; the instrumented fuel assembly irradiation program at Halden, Norway; and the experimental programs at the Power Burst Facility, Idaho National Engineering Laboratory. These programs will provide data for computer modeling of reactor system and fuel performance during various abnormal operating conditions.

Dotson, CW

1980-08-01

488

Annotating Sanskrit Corpus: Adapting IL-POSTS  

Microsoft Academic Search

\\u000a In this paper we present an experiment on the use of the hierarchical Indic Languages POS\\u000a Tagset (IL-POSTS) (Baskaran et al 2008 a&b), developed by Microsoft Research India (MSRI) for tagging Indian languages, for\\u000a annotating Sanskrit corpus. Sanskrit is a language with richer morphology and relatively free word-order. The authors have\\u000a included and excluded certain tags according to the requirements

Girish Nath Jha; Madhav Gopal; Diwakar Mishra

2009-01-01

489

Analysis of US child care safety regulations.  

PubMed Central

BACKGROUND: With 1.9 million US children cared for in organized group child care, the safety of these children is a public health concern. In the absence of federal policy, each state has developed its own day care safety regulations. METHODS: After creating a set of 36 criteria from three sets of national guidelines, we assessed the safety regulations of 45 states. With a mailed survey of state day care regulatory personnel, we examined the processes of formulating and implementing safety policy in 47 states. RESULTS: For 24 of the 36 items, more than half the states' regulations were below the criteria or failed to mention the topic. Most notable is the inattention to playground safety, choking hazards, and firearms. CONCLUSION: The uneven quality of regulations may be a reflection of a regulatory process that is fragmented, with many different groups sharing authority and with limited involvement of injury prevention specialists.

Runyan, C W; Gray, D E; Kotch, J B; Kreuter, M W

1991-01-01

490

The safety of foods developed by biotechnology  

SciTech Connect

Recombinant DNA techniques are now being used to develop new plant varieties that will be sources of foods, such as fruits, vegetables, grains, and their by-products. These techniques enable developers to make specific genetic modifications in plants, including modifications that introduce substances into plants that could not be introduced by traditional methods. To ensure the safety of the resulting foods and to foster innovation, the FDA is taking the initiative, before foods from such plants are ready to enter the market, to see that there is an agreed upon scientific basis to evaluate the safety of whole foods and animal feeds derived from new plant varieties. Here, the authors summarize their regulatory framework and their approach to safety assessment and discuss its scientific basis. Their safety assessment approach addresses new varieties of food crops developed by both traditional and newer methods of genetic modification and provides guidance on how safety issues should be addressed.

Kessler, D.A.; Taylor, M.R.; Maryanski, J.H.; Flamm, E.L.; Kahl, L.S. (Food and Drug Administration, Rockville, Maryland (United States))

1992-06-26

491

Perinatal Safety: From Concept to Nursing Practice  

PubMed Central

Communication and teamwork problems are leading causes of documented preventable adverse outcomes in perinatal care. An essential component of perinatal safety is the organizational culture in which clinicians work. Clinicians’ individual and collective authority to question the plan of care and take action to change the direction of a clinical situation in the patient’s best interest can be viewed as their “agency for safety.” However, collective agency for safety and commitment to support nurses in their advocacy role is missing in many perinatal care settings. This paper draws from Organizational Accident Theory, High Reliability Theory, and Symbolic Interactionism to describe the nurse’s role in maintaining safety during labor and birth in acute care settings, and suggests actions for supporting the perinatal nurse at individual, group, and systems levels to achieve maximum safety in perinatal care.

Kennedy, Holly Powell

2010-01-01

492

POST NATAL ACUPUNCTURE  

Microsoft Academic Search

Traditional Chinese medicine has very firm ideas on the amount of care and rest appropriate to the first month or longer after childbirth that contrast with the modern emphasis on returning to normal activities within a week or two. Recovery after childbirth can be promoted by appropriate tonifying acupuncture treatments and dietary advice. Furthermore specific problems post-birth, for example persistent

Debra Betts

493

Post-radiotherapy acupuncture  

Microsoft Academic Search

SummaryShortly following mastectomy and radiotherapy 17 years ago for cancer of the breast, post-radiation brachial plexus neuralgia had developed, together with a weeping radiation ulcer along the scar. The lady also suffered from multiple sclerosis with peripheral sensation loss, such that she was unable to walk properly, often burnt her hands and arms, and could not manage fine movements of

Shanti Rajan

1999-01-01

494

Post-transplant hyperlipidaemia.  

PubMed Central

The correction of post-transplant hyperlipidaemia warrants the judicious and timely use of pharmacological agents with dietary modification and exercise. Reduction in hyperlipidaemia may have some role in decreasing the incidence of chronic rejection of allografts. The awareness that the morbidity and mortality of atherosclerotic disease may be lowered by active intervention will result in a better quality of life for transplant recipients.

Jindal, R. M.

1997-01-01

495

41 CFR 302-9.204 - What is the âauthorized point of originâ when I transport my POV from my post of duty?  

Code of Federal Regulations, 2011 CFR

...âauthorized point of originâ when I transport my POV from my post of duty...authorized point of originâ when I transport my POV from my post of duty...authorized point of originâ when you transport your POV from your post of...

2011-07-01

496

41 CFR 302-9.204 - What is the âauthorized point of originâ when I transport my POV from my post of duty?  

Code of Federal Regulations, 2012 CFR

...âauthorized point of originâ when I transport my POV from my post of duty...authorized point of originâ when I transport my POV from my post of duty...authorized point of originâ when you transport your POV from your post of...

2012-07-01

497

Safety Evaluation Report of the Waste Isolation Pilot Plant Contact Handled (CH) Waste Documented Safety Analysis  

SciTech Connect

This Safety Evaluation Report (SER) documents the Department of Energy’s (DOE's) review of Revision 9 of the Waste Isolation Pilot Plant Contact Handled (CH) Waste Documented Safety Analysis, DOE/WIPP-95-2065 (WIPP CH DSA), and provides the DOE Approval Authority with the basis for approving the document. It concludes that the safety basis documented in the WIPP CH DSA is comprehensive, correct, and commensurate with hazards associated with CH waste disposal operations. The WIPP CH DSA and associated technical safety requirements (TSRs) were developed in accordance with 10 CFR 830, Nuclear Safety Management, and DOE-STD-3009-94, Preparation Guide for U. S. Department of Energy Nonreactor Nuclear Safety Analysis Reports.

Washington TRU Solutions LLC

2005-09-01

498

61 FR 36286 - Delegation of Authority  

Federal Register 2010, 2011, 2012, 2013

...Requirements for the 1996 Summer Olympic Games, Atlanta, GA, to the Regional...other safety personnel during the Olympic Games. EFFECTIVE DATE: July 10, 1996...operations requirements for the XXVI Olympic Games. This regulation is to...

1996-07-10

499

48 CFR 23.201 - Authorities.  

Code of Federal Regulations, 2012 CFR

...ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Energy and Water Efficiency and Renewable Energy 23.201...

2012-10-01

500

48 CFR 23.201 - Authorities.  

Code of Federal Regulations, 2011 CFR

...ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Energy and Water Efficiency and Renewable Energy 23.201...

2011-10-01