Sample records for praziquantel em uma

  1. 21 CFR 520.1200 - Ivermectin, fenbendazole, and praziquantel tablets.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...Ivermectin, fenbendazole, and praziquantel tablets. 520.1200 Section 520.1200 Food...Ivermectin, fenbendazole, and praziquantel tablets. (a) Specifications . Each chewable tablet contains either: (1) 68...

  2. 21 CFR 520.1200 - Ivermectin, fenbendazole, and praziquantel tablets.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...Ivermectin, fenbendazole, and praziquantel tablets. 520.1200 Section 520.1200 Food...Ivermectin, fenbendazole, and praziquantel tablets. (a) Specifications . Each chewable tablet contains either: (1) 68...

  3. Praziquantel, Mefloquine-Praziquantel, and Mefloquine-Artesunate-Praziquantel against Schistosoma haematobium: A Randomized, Exploratory, Open-Label Trial

    PubMed Central

    Keiser, Jennifer; Silué, Kigbafori D.; Adiossan, Lukas K.; N'Guessan, Nicaise A.; Monsan, N'Chou; Utzinger, Jürg; N'Goran, Eliézer K.

    2014-01-01

    Background Treatment and morbidity control of schistosomiasis relies on a single drug, praziquantel. Hence, there is a pressing need to develop additional therapeutics against schistosomiasis. The antimalarial drug mefloquine shows antischistosomal activity in animal models and clinical trials, which calls for further investigations. Methodology We comparatively assessed the efficacy and tolerability of the following treatments against Schistosoma haematobium in school-aged children in Côte d'Ivoire: (i) praziquantel (40 mg/kg; standard treatment); (ii) mefloquine (25 mg/kg) combined with praziquantel (40 mg/kg); and (iii) mefloquine-artesunate (3× (100 mg artesunate +250 mg mefloquine)) combined with praziquantel (40 mg/kg) (treatments administered on subsequent days). Two urine samples were collected before, and on days 21–22 and 78–79 after the first dosing. Principal Findings Sixty-one children were present on all examination time points and had complete datasets. No difference in efficacy was observed between the three treatment groups on either follow-up. On the 21–22 day posttreatment follow-up, based on available case analysis, cure rates of 33% (95% confidence interval (CI) 11–55%), 29% (95% CI 8–50%), and 26% (95% CI 5–48%) were observed for praziquantel, mefloquine-artesunate-praziquantel, and mefloquine-praziquantel, respectively. The corresponding egg reduction rates were 94% and above. On the second follow-up, observed cure rates ranged from 19% (praziquantel) to 33% (mefloquine-artesunate-praziquantel), and egg reduction rates were above 90%. Praziquantel monotherapy was the best tolerated treatment. In the mefloquine-artesunate-praziquantel group, adverse events were reported by 91% of the participants, and in the mefloquine-praziquantel group, 95% experienced adverse events. With the exception of abdominal pain at moderate severity, adverse events were mild. Conclusions/Significance The addition of mefloquine or mefloquine-artesunate does not increase the efficacy of praziquantel against chronic S. haematobium infection. Additional studies are necessary to elucidate the effect of the combinations against acute schistosomiasis. PMID:25033291

  4. (7) PRÁTICAS DE EDUCAÇÃO AMBIENTAL EM AULAS DE QUÍMICA EM UMA VISÃO SOCIOAMBIENTAL: PERSPECTIVAS E DESAFIOS

    Microsoft Academic Search

    Wildson L. P. Santos; Patrícia F. L. Machado; Roseli T. Matsunaga; Elton L. Silva; Erlete S. Vasconcellos; Valéria R. Santana

    2010-01-01

    Neste artigo, são apresentados resultados obtidos em quatro estudos de casos sobre a introdução de educação ambiental em uma visão socioambiental em aulas de Química. A discussão dos resultados levanta reflexões sobre perspectivas e desafios para a educação ambiental no ensino de Química. São demonstradas sugestões de atividades possíveis de serem desenvolvidas em aulas de Químicas. Várias fontes de dados

  5. Praziquantel Treatment in Trematode and Cestode Infections: An Update

    PubMed Central

    2013-01-01

    Status and emerging issues in the use of praziquantel for treatment of human trematode and cestode infections are briefly reviewed. Since praziquantel was first introduced as a broadspectrum anthelmintic in 1975, innumerable articles describing its successful use in the treatment of the majority of human-infecting trematodes and cestodes have been published. The target trematode and cestode diseases include schistosomiasis, clonorchiasis and opisthorchiasis, paragonimiasis, heterophyidiasis, echinostomiasis, fasciolopsiasis, neodiplostomiasis, gymnophalloidiasis, taeniases, diphyllobothriasis, hymenolepiasis, and cysticercosis. However, Fasciola hepatica and Fasciola gigantica infections are refractory to praziquantel, for which triclabendazole, an alternative drug, is necessary. In addition, larval cestode infections, particularly hydatid disease and sparganosis, are not successfully treated by praziquantel. The precise mechanism of action of praziquantel is still poorly understood. There are also emerging problems with praziquantel treatment, which include the appearance of drug resistance in the treatment of Schistosoma mansoni and possibly Schistosoma japonicum, along with allergic or hypersensitivity reactions against praziquantel treatment. To cope with and overcome these problems, combined use of drugs, i.e., praziquantel and other newly introduced compounds such as triclabendazole, artemisinins, and tribendimidine, is being tried. PMID:24265948

  6. 21 CFR 520.1871 - Praziquantel and pyrantel.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... (a) Specifications . (1) Each tablet contains 18.2 milligrams (mg) praziquantel...pyrantel pamoate). (2) Each chewable tablet contains 30 mg praziquantel and 30 mg...chapter. (1) See No. 000859 for use of tablet described in paragraph (a)(1)...

  7. Praziquantel treatment in trematode and cestode infections: an update.

    PubMed

    Chai, Jong-Yil

    2013-03-01

    Status and emerging issues in the use of praziquantel for treatment of human trematode and cestode infections are briefly reviewed. Since praziquantel was first introduced as a broadspectrum anthelmintic in 1975, innumerable articles describing its successful use in the treatment of the majority of human-infecting trematodes and cestodes have been published. The target trematode and cestode diseases include schistosomiasis, clonorchiasis and opisthorchiasis, paragonimiasis, heterophyidiasis, echinostomiasis, fasciolopsiasis, neodiplostomiasis, gymnophalloidiasis, taeniases, diphyllobothriasis, hymenolepiasis, and cysticercosis. However, Fasciola hepatica and Fasciola gigantica infections are refractory to praziquantel, for which triclabendazole, an alternative drug, is necessary. In addition, larval cestode infections, particularly hydatid disease and sparganosis, are not successfully treated by praziquantel. The precise mechanism of action of praziquantel is still poorly understood. There are also emerging problems with praziquantel treatment, which include the appearance of drug resistance in the treatment of Schistosoma mansoni and possibly Schistosoma japonicum, along with allergic or hypersensitivity reactions against praziquantel treatment. To cope with and overcome these problems, combined use of drugs, i.e., praziquantel and other newly introduced compounds such as triclabendazole, artemisinins, and tribendimidine, is being tried. PMID:24265948

  8. Inhibition of phosphoinositide turnover by praziquantel in Schistosoma mansoni.

    PubMed

    Wiest, P M; Li, Y; Olds, G R; Bowen, W D

    1992-08-01

    The effect of praziquantel on phosphoinositide turnover was examined in Schistosoma mansoni to determine if this anthelminthic modulates signal transduction pathways in parasites. Adult worms were radiolabeled with [3H]myoinositol for 24 hr and total inositol phosphate levels determined in the presence of praziquantel. Praziquantel inhibited inositol phosphate turnover when activated with NaF plus AlCl3 or with the nonhydrolyzable guanine nucleotide-binding protein analogue GTP gamma S. Furthermore, praziquantel decreased basal turnover of inositol phosphates. Inhibition was seen in both male and female worms as well as in schistosomula. These data indicate that inhibition of phosphoinositide turnover may contribute to the effect of praziquantel on parasite survival within the definitive host. PMID:1321906

  9. O que TerraMA2 ? ... um sistema computacional, baseado em uma

    E-print Network

    Domingues, Margarete Oliveira

    O que é TerraMA2 ? ... é um sistema computacional, baseado em uma arquitetura de serviços, aberta exemplos são: qualidade do ar, qualidade da água, epidemias, gasodutos, barragens de rejeito em área de marés com ressacas em regiões portuárias, dentre outros. Que tipos de dados posso coletar na internet

  10. 21 CFR 524.775 - Emodepside and praziquantel.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...12 mg/kg) praziquantel applied as a single topical dose. (2) Indications for use . For the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm...

  11. 21 CFR 524.775 - Emodepside and praziquantel.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...12 mg/kg) praziquantel applied as a single topical dose. (2) Indications for use . For the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm...

  12. 21 CFR 524.775 - Emodepside and praziquantel.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...12 mg/kg) praziquantel applied as a single topical dose. (2) Indications for use . For the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm...

  13. 21 CFR 524.775 - Emodepside and praziquantel.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...12 mg/kg) praziquantel applied as a single topical dose. (2) Indications for use . For the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm...

  14. 21 CFR 524.775 - Emodepside and praziquantel.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...12 mg/kg) praziquantel applied as a single topical dose. (2) Indications for use. For the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm...

  15. Effects of praziquantel on experimental Schistosoma bovis infection in goats

    Microsoft Academic Search

    Maria V. Johansen; Jesper Monrad; Niels Ø. Christensen

    1996-01-01

    The effect of praziquantel against experimental Schistosoma bovis infection in West African Dwarf goats was investigated. Thirty goats were exposed to 2000 cercariae each and 15 of those received a praziquantel treatment (60 mg kg?1) 13 weeks post-infection. One day, 1 week and 4 weeks post-treatment representative goats from each group were killed and worms were recovered by perfusion. For

  16. 21 CFR 520.1872 - Praziquantel, pyrantel pamoate, and febantel tablets.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...Praziquantel, pyrantel pamoate, and febantel tablets. 520.1872 Section 520.1872 Food and...Praziquantel, pyrantel pamoate, and febantel tablets. (a) Specifications . Each tablet or chewable tablet contains either:...

  17. 21 CFR 520.1872 - Praziquantel, pyrantel pamoate, and febantel tablets.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...Praziquantel, pyrantel pamoate, and febantel tablets. 520.1872 Section 520.1872 Food and...Praziquantel, pyrantel pamoate, and febantel tablets. (a) Specifications . Each tablet or chewable tablet contains either:...

  18. In vitro uptake of /sup 14/C-praziquantel by cestodes, trematodes, and a nematode

    SciTech Connect

    Andrews, P.; Thomas, H.; Weber, H.

    1980-12-01

    /sup 14/C-praziquantel was rapidly taken up by Schistosoma mansoni, Fasciola hepatica, Hymenolepis nana, and isolated strobilocerci of Taenia taeniaeformis. Schistosoma mansoni lost praziquantel rapidly to drug-free medium. Chromatography of extracts prepared after incubation of S. mansoni and H. nana yielded no indication that praziquantel was metabolized. Autoradiography revealed a uniform distribution of praziquantel throughout the tissues of S. mansoni and H. nana. Uptake was considerably slower in the nematode Heterakis spumosa and apparently via the oral route.

  19. Cytochalasin D abolishes the schistosomicidal activity of praziquantel.

    PubMed

    Pica-Mattoccia, Livia; Valle, Cristiana; Basso, Annalisa; Troiani, Anna Rita; Vigorosi, Fabio; Liberti, Piero; Festucci, Alfredo; Cioli, Donato

    2007-04-01

    To test the hypothesis that calcium channels of schistosomes are the targets for the action of praziquantel, we subjected schistosomes in vitro to pharmacological agents capable of interfering with the functioning of calcium channels. After 1-h exposure to these agents, praziquantel was added and incubation continued overnight. Worms were then washed, resuspended in drug-free medium and observed during the following 7-10 days. About 50% of schistosomes pre-exposed to the calcium channel blockers nicardipine and nifedipine were able to survive a praziquantel concentration (3 microM) that normally killed the majority of adult male worms. Since the organization of the actin cytoskeleton controls the activity of calcium channels in a number of different systems, we also pre-exposed schistosomes to the actin depolymerizing agent cytochalasin D. This treatment rendered the parasites completely refractory to the effects of very high praziquantel levels (up to 36 microM). These results are consistent with the hypothesis that schistosome calcium channels are involved in the mechanism of action of praziquantel. PMID:17083933

  20. ARALES DE LAGOAS EM UMA ÁREA DO SEMI-ÁRIDO BAIANO

    Microsoft Academic Search

    Márcia Gonçalves Bezerra; Flávio França

    RESUMO — O presente trabalho trata das espécies de Arales ocorrentes em lagoas de uma área do semi-árido baiano. A ordem apresenta, no local, duas famílias com cinco espécies: Lemna valdiviana Phil., Lemna aequinoctialis Welwitsch, Wolffiella lingulata (Hegelm.) Hegelm. e Wolffia columbiana Karsten (LEMNACEAE) e Pistia stratiotes L. (ARACEAE). PALAVRAS-CHAVE: Arales; plantas aquáticas; Lemnaceae; Araceae. ABSTRACT — This paper presents

  1. Operadores positivos em dimens\\~ao finita: uma caracteriza\\c{c}\\~ao

    E-print Network

    Fassarella, L

    2011-01-01

    A characterization of positive operators in finite dimensional complex vector spaces based on the Routh-Hurwitz Criterion. ----- Uma caracteriza\\c{c}\\~ao dos operadores positivos em espa\\c{c}os vetoriais complexos de dimens\\~ao finita a partir do Crit\\'erio de Routh-Hurwitz.

  2. 21 CFR 520.903d - Febantel-praziquantel paste.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...milligrams of praziquantel per kilogram of body weight (1 gram of paste per 5 pounds body weight) administered by mouth on a full stomach once daily for 3 days. (2) Indications for use. (i) Dogs and puppies: For removal of hookworms (Ancylostoma...

  3. 21 CFR 520.903d - Febantel-praziquantel paste.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...milligrams of praziquantel per kilogram of body weight (1 gram of paste per 5 pounds body weight) administered by mouth on a full stomach once daily for 3 days. (2) Indications for use. (i) Dogs and puppies: For removal of hookworms (Ancylostoma...

  4. Praziquantel Affects the Regulatory Myosin Light Chain of Schistosoma mansoni

    Microsoft Academic Search

    Munirathinam Gnanasekar; Ashok M. Salunkhe; A. Krishna Mallia; Yi Xun He; Ramaswamy Kalyanasundaram

    2009-01-01

    Praziquantel (PZQ) is the drug of choice for schistosomiasis and probably is the only highly effective drug currently available for treating schistosomiasis-infected individuals. The mode of action of PZQ involves increasing the calcium uptake of the parasite, resulting in tegumental damage and death of the parasite. Despite its remarkable function, the target of PZQ has not been identified yet. To

  5. Liver flukes in dogs and treatment with praziquantel.

    PubMed

    Schuster, R K; Heidrich, J; Pauly, A; Nöckler, K

    2007-12-25

    Opisthorchiid eggs were found in 6 out of 27 (22%) huskies while an ELISA detected antibodies against Opisthorchis felineus and Metorchis bilis in 24 (89%) and 25 (93%) sera taken from these dogs, respectively. All dogs showed an increased activity of glutamate dehydrogenase while aspartate aminotransferase was normal in all samples. Ten weeks after treatment with praziquantel no fluke eggs were found in the faeces from any animal and antibody titres dropped in all animals. PMID:17981396

  6. THE ACUTE TOXICITY OF PRAZIQUANTEL TO GRASS CARP AND GOLDEN SHINERS

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Acute praziquantel toxicity and no observable effect concentrations (NOEC), were determined in the laboratory for grass carp and golden shiners, two commercially raised cyprinids known to harbor Asian tapeworm Bothriocephalus acheilognathi. Praziquantel is an anthelmintic used to treat fish with ta...

  7. Uso de modelos mecânicos em curso informal de astronomia para deficientes visuais. Resgate de uma experiência

    NASA Astrophysics Data System (ADS)

    Tavares, E. T., Jr.; Klafke, J. C.

    2003-08-01

    O presente trabalho propõe-se a resgatar uma experiência que teve lugar no Planetário de São Paulo nos anos 60. Em 1962, o Sr. Acácio, então com 37 anos, deficiente visual desde os 27, passou a assistir às aulas ministradas pelo Prof. Aristóteles Orsini aos integrantes do corpo de servidores do Planetário. O Sr. Acácio era o único deficiente da turma e, embora possuísse conhecimentos básicos e relativamente avançados de matemática, enfrentava dificuldades na compreensão e acompanhamento da exposição, como também em estudos posteriores. Com o intuito de auxiliá-lo na superação desses problemas, o Prof. Orsini solicitou a construção de modelos mecânicos que, através do sentido do tato, permitissem o acompanhamento das aulas e a transposição do modelo para o "constructo" mental. Essa prática mostrou-se tão eficaz que facilitou sobejamente o aprendizado da matéria pelo sujeito. O Sr. Acácio passou a integrar o corpo de professores do Planetário/Escola Municipal de Astrofísica, tendo ficado responsável pelo curso de "Introdução à Astronomia" por vários anos. Além disso, a experiência foi tão bem sucedida que alguns dos modelos tiveram seus elementos constitutivos pintados diferencialmente para serem utilizados em cursos regulares do Planetário, tornando-se parte integrante do conjunto de recursos didáticos da instituição. É pensando nessa eficácia, tanto em seu objetivo original permitir o aprendizado de um deficiente visual quanto no subsidiário recurso didático sistemático da instituição que decidimos resgatar essa experiência. Estribados nela, acreditamos ser extremamente produtivo, em termos educacionais, o aperfeiçoamento dos modelos originais, agora resgatados e restaurados, e a criação de outros que pudessem ser utilizados no ensino dessa ciência a deficientes visuais.

  8. Synthesis of fluorescent derivatives of praziquantel: cell-imaging and interaction with Schistosoma japonicum cercariae.

    PubMed

    Xie, Yunzhi; Li, Yibao; Wu, Yongquan; Liu, Chunhua; Li, Xiaokang; Li, Xun; Fan, Xiaolin

    2013-09-28

    Schistosomiasis is one of the most burdensome of the neglected tropical diseases. Praziquantel is a recommended drug for treatment against all forms of schistosomiasis. To investigate the interaction between praziquantel and Schistosoma japonicum cercariae, two praziquantel derivatives (PZQ-2 and PZQ-3) and one praziquantel fluorescent derivative (PZQ-5) have been synthesized and characterized using nuclear magnetic resonance spectroscopy (NMR) and MS spectra. The cytotoxicity of PZQ-2, PZQ-3 and PZQ-5 was measured by performing the methyl thiazolyl tetrazolium (MTT) assay. The cell viability for them shows that the three compounds exhibit low cytotoxicity to HeLa cells. Cell imaging experiments demonstrate that PZQ-5 is biocompatible and cell-permeable, which indicates that PZQ-5 is suitable for studying their interaction. Confocal fluorescence microscopy revealed that PZQ-5 is mainly located at the cercarial tegument, which leads to the death of cercariae with the increase in time. PMID:23925274

  9. Comparison of albendazole, mebendazole and praziquantel chemotherapy of Echinococcus multilocularis in a gerbil model

    Microsoft Academic Search

    D H Taylor; D L Morris; D Reffin; K S Richards

    1989-01-01

    The efficacy of albendazole (50 mg\\/kg\\/d), mebendazole (50 mg\\/kg\\/d) and praziquantel (500 mg\\/kg\\/d) against established intraperitoneal infections of Echinococcus multilocularis in gerbils was compared by monitoring parasite weight and making ultrastructural observations on treated and untreated material. Praziquantel was the most active protoscolicidal agent, reducing protoscolex viability to less than 2%, although it did not inhibit cyst growth. Albendazole was

  10. Transdermal evaporation delivery system of praziquantel for schistosomiasis japonicum chemotherapy.

    PubMed

    Wang, Lei; Zheng, Xinsheng; Fang, Yan; Wang, Yi; Duan, Cunzheng; Yao, Baoan

    2011-07-01

    A transdermal evaporation delivery system (TEDS) of praziquantel (PZQ) was developed by selecting ethylene glycol monophenyl ether as a nonvolatile component solvent and ethanol as a volatile component solvent to control efficiently the transmission and morbidity of the global schistosomiasis, providing a convenient administration system of PZQ for both humans and domestic animals. The solubility of PZQ in TEDS was more than 400 mg/mL when the ethanol concentration was 50% (w/w) in the solvent mixture at 32 °C, enabling to adapt requirements for the treatment of schistosomiasis. The highest serum drug concentration reached 35.93 µg/mL after transdermal administration of TEDS of PZQ in rabbits, being 6.3-fold higher than that after oral administration at the same dose. The TEDS of PZQ achieved treatment efficacy with the worm reduction of 100% when it was applied in the experimental treatment of Schistosoma japonicum in rabbits. The TEDS of PZQ that provides passive and nonocclusive delivery, having the inexpensive cost, low skin irritation rates, and precise dose of administration, should find application in the transmission control and chemotherapy of global schistosomiasis. PMID:21319162

  11. Comparison of albendazole, mebendazole and praziquantel chemotherapy of Echinococcus multilocularis in a gerbil model.

    PubMed Central

    Taylor, D H; Morris, D L; Reffin, D; Richards, K S

    1989-01-01

    The efficacy of albendazole (50 mg/kg/d), mebendazole (50 mg/kg/d) and praziquantel (500 mg/kg/d) against established intraperitoneal infections of Echinococcus multilocularis in gerbils was compared by monitoring parasite weight and making ultrastructural observations on treated and untreated material. Praziquantel was the most active protoscolicidal agent, reducing protoscolex viability to less than 2%, although it did not inhibit cyst growth. Albendazole was the most effective agent in reducing cyst growth and was, when compared with other regimes significantly more effective than mebendazole (p less than 0.05), praziquantel (p less than 0.01) or untreated controls (p less than 0.01). Images Fig. 2 Fig. 3 Fig. 4 Fig. 5 Fig. 6 Fig. 7 Fig. 8 Fig. 9 PMID:2583567

  12. A Fluorometric method for the determination of praziquantel in blood-plasma and urine

    Microsoft Academic Search

    J. Pütter

    1979-01-01

    Summary  Some physicochemical data of praziquantel which may have analytical relevance are reported.\\u000a \\u000a For the quantitative determination praziquantel is extracted from plasma or urine by means of organic solvents and then hydrolyzed\\u000a in an aqueous alkaline solution. The hydrolyzed product is reacted with dansyl-chloride (5-dimethylaminonaphthalene-sulfonylchloride).\\u000a The dansylated compound is separated and quantified fluorometrically.\\u000a \\u000a \\u000a \\u000a The limit of determination is 3 JUg\\/1 in

  13. Failure of one-day praziquantel treatment in patients with multiple neurocysticercosis lesions.

    PubMed

    Pretell, E J; García, H H; Gilman, R H; Saavedra, H; Martinez, M

    2001-10-01

    A recently described one-day regimen of praziquantel (PZQ) therapy for neurocysticercosis (NCC), three doses of 25 mg/k given at 2 h intervals, was applied in eight patients with viable NCC cysts without any evidence of inflammation. Resolution of lesions in computed tomography (CT) was observed in all five patients with a single cyst, whereas all cysts survived in three patients with multiple brain parasites. One-day praziquantel is a good regimen for patients with a single viable brain cysticercus but is poorly effective for multiple cysts. PMID:11532559

  14. Effectiveness of different approaches to mass delivery of praziquantel among school-aged children in rural communities in Nigeria.

    PubMed

    Mafe, M A; Appelt, B; Adewale, B; Idowu, E T; Akinwale, O P; Adeneye, A K; Manafa, O U; Sulyman, M A; Akande, O D; Omotola, B D

    2005-02-01

    Schistosomiasis is hyperendemic in Nigeria. The national policy on schistosomiasis control has adopted praziquantel as the main drug of use in the control strategy aimed at reducing morbidity. However, the best delivery channel for praziquantel in schistosomiasis control in Nigeria is yet to be determined. This study assessed different channels for praziquantel delivery in a mass treatment effort. Three groups, each of two communities, were assigned to one of the following three channels: health facility (HF), school, and community for mass delivery of praziquantel to school-aged children. Distributors were trained on all aspects of praziquantel distribution and sufficient praziquantel tablets were provided for the drug distribution within 3 weeks following which an evaluation of the drug distribution by the different treatment channels was conducted. Overall, the community channel of delivery achieved the best coverage of 72.2% (range: 69-73%) compared to 44.3% (range: 39.5-62%) and 28.5% (range: 26.3-74.5%) for the HF and school channels, respectively. Community channel of praziquantel delivery as shown in this study ensures good coverage of both in and out-of-school children. PMID:15652332

  15. Praziquantel sensitivity of Kenyan Schistosoma mansoni isolates and the generation of a laboratory strain with reduced susceptibility to the drug

    PubMed Central

    Mwangi, Ibrahim N.; Sanchez, Melissa C.; Mkoji, Gerald M.; Agola, Lelo E.; Runo, Steven M.; Cupit, Pauline M.; Cunningham, Charles

    2014-01-01

    Schistosomiasis is a neglected tropical disease caused by blood-dwelling flukes of the genus Schistosoma. While the disease may affect as many as 249 million people, treatment largely relies on a single drug, praziquantel. The near exclusive use of this drug for such a prevalent disease has led to concerns regarding the potential for drug resistance to arise and the effect this would have on affected populations. In this study, we use an in vitro assay of drug sensitivity to test the effect of praziquantel on miracidia hatched from eggs obtained from fecal samples of Kenyan adult car washers and sand harvesters as well as school children. Whereas in a previous study we found the car washers and sand harvesters to harbor Schistosoma mansoni with reduced praziquantel sensitivity, we found no evidence for the presence of such strains in any of the groups tested here. Using miracidia derived from seven car washers to infect snails, we used the shed cercariae to establish a strain of S. mansoni with significantly reduced praziquantel sensitivity in mice. This was achieved within 5 generations by administering increasing doses of praziquantel to the infected mice until the parasites could withstand a normally lethal dose. This result indicates that while the threat of praziquantel resistance may have diminished in the Kenyan populations tested here, there is a strong likelihood it could return if sufficient praziquantel pressure is applied. PMID:25516840

  16. Activity of tribendimidine and praziquantel combination therapy against the liver fluke Opisthorchis viverrini in vitro and in vivo.

    PubMed

    Keiser, J; Adelfio, R; Vargas, M; Odermatt, P; Tesana, S

    2013-06-01

    Opisthorchiasis, caused by the liver fluke Opisthorchis viverrini, a food-borne trematode, is an important public health problem; however, only a single drug, praziquantel is available. We investigated tribendimidine-praziquantel combinations against O. viverrini in vitro and in vivo. The IC50 values of 0.16 ?g/ml and 0.05 ?g/ml were determined for praziquantel and tribendimidine, respectively, against adult O. viverrini in vitro. When O. viverrini was exposed to both drugs simultaneously (using a drug ratio based on the IC50 (1:3.2)) a synergistic effect was calculated (combination index (CI) at the IC50= 0.7). A similar result was observed when drug addition in vitro was spaced by the respective half-lives of the drugs (a CI of 0.78 at the IC50 for tribendimidine followed by praziquantel and a CI of 0.47 at the IC50 for praziquantel followed by tribendimidine). In vivo median-effect dose (ED50) values of 191 mg/kg and 147 mg/kg were calculated for praziquantel and tribendimidine, respectively. Low to moderate worm burden reductions (38-62%) were observed in O. viverrini infected hamsters when both drugs were administered simultaneously or on subsequent days, pointing to antagonistic effects in vivo. Further studies are necessary to understand the striking differences between the in vitro and in vivo observations using combinations of praziquantel and tribendimidine on O. viverrini. PMID:22892101

  17. Combination chemotherapy against Clonorchis sinensis: experiments with artemether, artesunate, OZ78, praziquantel, and tribendimidine in a rat model.

    PubMed

    Keiser, Jennifer; Xiao, Shu-Hua; Smith, Thomas A; Utzinger, Jürg

    2009-09-01

    Caused by the Chinese liver fluke Clonorchis sinensis, clonorchiasis is of growing public health importance. Treatment and control of the disease rely on a single drug, praziquantel, and little information regarding combination chemotherapy is available. Here, we evaluated the in vivo efficacy of praziquantel combined with artemether, artesunate, OZ78, and tribendimidine, as well as an artesunate-tribendimidine combination against C. sinensis, in a rat model. Data from previous experiments were included, and negative binomial regression analyses were carried out to determine dose-response relationships and to study the effect of drug combination. All drugs given in monotherapy were efficacious in killing the worms; doses of 16 and 70 mg/kg of body weight of artesunate, for example, reduced worm burden by 50% and 95%, respectively. Artemether and OZ78 (12.5 to 50 mg/kg) showed dose-dependent killing of worms but no significant drug interactions when given with 150 mg/kg praziquantel, suggesting independent additive effects. In contrast, artesunate and tribendimidine (12.5 to 50 mg/kg) showed synergistic interactions with 150 mg/kg praziquantel. When low doses of 3.1 and 6.25 mg/kg OZ78 and artemether, respectively, were combined with praziquantel (150 mg/kg) an increased worm survival, above the level observed with praziquantel monotherapy, was noted. A similar antagonism was seen when praziquantel (75 mg/kg) was combined with several of the companion drugs at various doses. In conclusion, in vivo efficacy of praziquantel, the artemisinins, OZ78, and tribendimidine against C. sinensis is confirmed, and combination chemotherapy with praziquantel produces synergistic and antagonistic effects depending on the doses administered. Further preclinical investigations are warranted. PMID:19581454

  18. Combination Chemotherapy against Clonorchis sinensis: Experiments with Artemether, Artesunate, OZ78, Praziquantel, and Tribendimidine in a Rat Model?

    PubMed Central

    Keiser, Jennifer; Xiao, Shu-Hua; Smith, Thomas A.; Utzinger, Jürg

    2009-01-01

    Caused by the Chinese liver fluke Clonorchis sinensis, clonorchiasis is of growing public health importance. Treatment and control of the disease rely on a single drug, praziquantel, and little information regarding combination chemotherapy is available. Here, we evaluated the in vivo efficacy of praziquantel combined with artemether, artesunate, OZ78, and tribendimidine, as well as an artesunate-tribendimidine combination against C. sinensis, in a rat model. Data from previous experiments were included, and negative binomial regression analyses were carried out to determine dose-response relationships and to study the effect of drug combination. All drugs given in monotherapy were efficacious in killing the worms; doses of 16 and 70 mg/kg of body weight of artesunate, for example, reduced worm burden by 50% and 95%, respectively. Artemether and OZ78 (12.5 to 50 mg/kg) showed dose-dependent killing of worms but no significant drug interactions when given with 150 mg/kg praziquantel, suggesting independent additive effects. In contrast, artesunate and tribendimidine (12.5 to 50 mg/kg) showed synergistic interactions with 150 mg/kg praziquantel. When low doses of 3.1 and 6.25 mg/kg OZ78 and artemether, respectively, were combined with praziquantel (150 mg/kg) an increased worm survival, above the level observed with praziquantel monotherapy, was noted. A similar antagonism was seen when praziquantel (75 mg/kg) was combined with several of the companion drugs at various doses. In conclusion, in vivo efficacy of praziquantel, the artemisinins, OZ78, and tribendimidine against C. sinensis is confirmed, and combination chemotherapy with praziquantel produces synergistic and antagonistic effects depending on the doses administered. Further preclinical investigations are warranted. PMID:19581454

  19. Removal and Quantification of Asian Tapeworm from Bonytail Chub Using Praziquantel

    Microsoft Academic Search

    David L. Ward

    2007-01-01

    The spread of the Asian tapeworm Bothriocephalus acheilognathi has been identified as a potential threat to endangered cyprinid fishes, such as bonytail Gila elegans and humpback chub G. cypha. Praziquantel is often used to remove Asian tapeworms from these species, but little information is available on the effectiveness or side effects of these treatments. I performed laboratory experiments using bonytails

  20. Effect of Chemotherapy with Praziquantel on the Production of Cytokines and Morbidity Associated with Schistosomiasis Mansoni

    Microsoft Academic Search

    P. Martins-Leite; G. Gazzinelli; L. F. Alves-Oliveira; A. Gazzinelli; L. C. C. Malaquias; R. Correa-Oliveira; A. Teixeira-Carvalho; A. M. S. Silveira

    2008-01-01

    The objective of the present study was to test the hypothesis that treatment of schistosomiasis mansoni with praziquantel can alter significantly the immune response of patients and generate a reversal of the level of fibrosis. Peripheral blood mononuclear cell (PBMC) samples were collected from, and abdominal ultrasound examinations conducted on, volunteers infected with Schistosoma mansoni and living in an area

  1. Determination of the minmum effective dosages of praziquantel, albendazole, and mebendazole against Clonorchis sinensis infection in rats.

    PubMed

    Fan, Ping-Chin; Wu, Chin-Cheng; Huang, Ping; Yen, Chih-Wei

    2005-10-01

    In order to determine the minimum effective dosages of praziquantel, albendazole, and mebendazole against Clonorchis sinensis infection in Sprague-Dawley rats, each rat was infected with 30 metacercariae and treated with one of three drugs. The rats were killed and examined 25 days after praziquantel treatment or 11 days after albendazole or mebendazole treatment. The minimum effective dosages were a single dose of praziquantel 375 mg/kg, albendazole 150 mg/kg, and mebendazole 150 mg/kg. Trials are required to determine whether these dosages are useful in the treatment of human clonorchiasis. PMID:16302447

  2. Safety of the Combined Use of Praziquantel and Albendazole in the Treatment of Human Hydatid Disease

    PubMed Central

    Alvela-Suárez, Lucía; Velasco-Tirado, Virginia; Belhassen-Garcia, Moncef; Novo-Veleiro, Ignacio; Pardo-Lledías, Javier; Romero-Alegría, Angela; Pérez del Villar, Luis; Valverde-Merino, María Paz; Cordero-Sánchez, Miguel

    2014-01-01

    There is still no well-established consensus about the clinical management of hydatidosis. Currently, surgery continues to be the first therapeutic option, although treatment with anti-parasitic drugs is indicated as an adjuvant to surgery to decrease the number of relapses and hydatid cyst size. When surgery is not possible, medical treatment is indicated. Traditionally, albendazole was used in monotherapy as the standard treatment. However, combined therapy with albendazole plus praziquantel appears to improve anti-parasitic effectiveness. To date, no safety studies focusing on such combined therapy have been published for the treatment of hydatidosis. In this work, we analyze the adverse effects seen in 57 patients diagnosed with hydatidosis who were treated with praziquantel plus albendazole combined therapy between 2006 and 2010. PMID:24615131

  3. Field trial of praziquantel for control of fishborne zoonotic trematodes in reservoir hosts in Vietnam

    Microsoft Academic Search

    Nguyen Thi Lan Anh; Henry Madsen; Dao Thi Ha Thanh; Anders Dalsgaard; K. Darwin Murrell

    2010-01-01

    This field trial was conducted to determine whether 40 or 75mg\\/kg of praziquantel is suitable for treatment of fishborne zoonotic trematodes (FZT) in naturally infected dogs (n=10) and cats (n=11). Three days after treatment all animals at either dose were negative for small trematode eggs. In two cats and one dog treated with 75mg\\/kg, however, a few damaged eggs were

  4. Short regimen of praziquantel in the treatment of single brain enhancing lesions.

    PubMed

    Pretell, E J; Garcia, H H; Custodio, N; Padilla, C; Alvarado, M; Gilman, R H; Martinez, M

    2000-12-01

    Twenty-six patients with single enhancing brain lesion (SEL) were openly assigned to receive single-day praziquantel therapy (n=14), or not (n=12). From 14 treated patients, complete resolution was found in 11, partial resolution in two, and the remaining case was later diagnosed as an arteriovenous malformation. Side effects presented in only one patient and remitted in the same day with symptomatic treatment. Conversely, the lesions persisted unchanged in six of 12 patients in the non-treatment group. Untreated patients with persisting lesions were prescribed praziquantel treatment. After this, SELs disappeared in three cases, other diagnoses (brain tuberculoma and arteriovenous malformation) were made in two, and one was not evaluated. When analyzed in regard to the baseline serology, resolution of lesions on computed tomography was found in 13 (complete=12, partial=1) of 14 seropositive patients, whereas it only happened in six (complete=5, partial=1) of 12 seronegative patients. Serological screening defines a subset of SEL patients with good prognosis. If antiparasitic therapy is to be used in patients with SEL, and we cannot find a strong argument against it, single-day praziquantel is the regimen of choice based on duration, costs, and minimal side effects. PMID:11154807

  5. Efficacy and Safety of Praziquantel, Tribendimidine and Mebendazole in Patients with Co-infection of Clonorchis sinensis and Other Helminths

    PubMed Central

    Xu, Li-Li; Jiang, Bin; Duan, Ji-Hui; Zhuang, Shi-Feng; Liu, Yong-Chun; Zhu, Shi-Qiao; Zhang, Li-Ping; Zhang, Hao-Bing; Xiao, Shu-Hua; Zhou, Xiao-Nong

    2014-01-01

    Background Both tribendimidine and mebendazole are broad-spectrum drugs for anti-intestinal nematodes. We aim to assess the efficacy and safety of tribendimidine and mebendazole in patients with co-infection of Clonorchis sinensis and other helminths. Method We performed a randomized open-label trial in Qiyang, People's Republic of China. Eligible participants were randomly assigned to one of four groups: (i) a single dose of 400 mg tribendimidine, (ii) 200 mg tribendimidine twice daily, (iii) 75 mg/kg praziquantel divided in four doses within 2 days, and (iv) a single dose of 400 mg mebendazole. Cure rates and egg reduction rates were assessed, and adverse events were monitored after treatments. Uncured patients accepted the second treatment with the same drugs after the first treatment. Results 156 patients were eligible for the study. Results from the first treatment showed that the cure rates of single-dose tribendimidine and praziquantel against C. sinensis were 50% and 56.8%, respectively; the single-dose tribendimidine achieved the cure rate of 77.8% in the treatment for hookworm, which was significantly higher than that of praziquantel; Low cure rates were obtained in the treatment of single-dose tribendimidine against Ascaris lumbricoides and Trichuris trichiura (28.6% and 23.1%). Results of the second treatment illustrated the cure rates of tribendimidine and praziquantel against C. sinensis were 78.1% and 75%, respectively. Most adverse events were mild and transient. Adverse events caused by tribendimidine were significantly less than praziquantel. Conclusion Single-dose tribendimidine showed similar efficacy against C. sinensis as praziquantel with less adverse events, and achieved significantly higher cure rate in the treatment for hookworm than those of praziquantel and mebendazole. Low cure rates, which were still higher than other drugs, were obtained in the treatment of single-dose tribendimidine against Ascaris lumbricoides and Trichuris trichiura. Trial Registration Controlled-Trials.com ISRCTN55086560 PMID:25122121

  6. Comparative effect of mebendazole, albendazole, tribendimidine, and praziquantel in treatment of rats infected with Clonorchis sinensis.

    PubMed

    Xiao, Shu-hua; Xue, Jian; Xu, Li-li; Zhang, Yong-nian; Qiang, Hui-qin

    2011-03-01

    The aim of the study is to understand the anti-Clonorchis sinensis properties of mebendazole and albendazole, and compare to praziquantel and tribendimidine. Two hundred and thirty rats were divided into five batches for experimental treatment. In four batches, each rat was infected orally with 50 or 100 C. sinensis metacercariae. Twenty-eight to 46 days post-infection, groups of rats were treated orally with single doses of mebendazole, albendazole, praziquantel, tribendimidine, or multiple daily doses of albendazole. While in the remaining batch, mebendazole or praziquantel was administered to groups of rats infected each with 50 metacercariae for 7 or 14 days. In each batch of test, untreated but infected rats served as control. All rats were euthanized 2-4 weeks post-drug administration for assessment of efficacy. In the first batch of test, rats treated with mebendazole or tribendimidine at single doses of 150, 75, and 37.5 mg/kg resulted in worm burden reductions of 99.0%, 94.0%, and 73.1%, or 98.0%, 80.6%, and 60.4%, respectively. When rats were treated with albendazole at the same dose levels, no or poor effect was seen. In the second batch of test, promising effect against adult C. sinensis in rats treated with mebendazole or tribendimidine at single doses of 100 and 50 mg/kg were also observed, but under the single dose of 25 mg/kg, only tribendimidine still remained the effect. In the third batch of test, the aforementioned three single dose levels of mebendazole, albendazole and praziquantel were applied. Again, mebendazole exhibited higher effect and albendazole exhibited no or poor effect. While praziquantel, administered at a higher dose of 300 mg/kg, also showed promising effect. In the fourth batch of test, oral administration of albendazole at a daily dose of 150 or 100 mg/kg for 2 or 3 days resulted in moderate or higher efficacy with worm burden reductions of 79.2% and 91.9%, respectively. In the fifth batch of test, single mebendazole doses of 150 or 75 mg/kg exhibited promising effect against 14-day-old C. sinensis in rats with worm burden reductions of 95.3% and 86.4%, respectively, but mebendazole was short of the effect against 7-day-old worms. Under the same dose level, praziquantel possessed an effect against both 7- and 14-day-old juvenile C. sinensis. The results confirm that in infected rats, mebendazole administered orally at a single dose of 150 mg/kg exhibits potential effect against juvenile (14-day-old) and adult C. sinensis. No or less effect is obtained from albendazole under the same dose levels, but extension of treatment course may enhance the effect of albendazole against this species of fluke. The single effective dose ranges of mebendazole and tribendimidine against C. sinensis in rats are similar with a broad window, while the window for praziquantel is narrow. PMID:21136080

  7. Aplicao de dendrometria em uma floresta manejada com corte seletivo na Floresta Nacional do Tapajs Sousa. Cleilim Alberta, Figueira. Adelaine Michelaa, da Rocha. Humberto Ribeirob, Freitas. Helber Cb, Miller. Scott DC, Gouden. Michael LC, Menton. Mary CC.

    E-print Network

    Goulden, Michael L.

    Aplicação de dendrometria em uma floresta manejada com corte seletivo na Floresta Nacional do encontrados em clareiras de diferentes tamanhos. Assim sendo, a teoria de clareiras pode ser útil para o manejo de espécie tropicais dentro da estrutura da floresta em regeneração. O tamanho da clareira tem um

  8. Clinical pharmacology in normal volunteers of praziquantel, a new drug against schistosomes and cestodes

    Microsoft Academic Search

    G. Leopold; W. Ungethiim; E. Groll; H. W. Diekmann; H. Nowak; D. H. G. Wegner

    1978-01-01

    The tolerance of Praziquantel (2-cyclohexylcarbonyl-1, 3, 4, 6, 7, 11b-hexahydro-2H-pyrazino-[2, 1-a]isoquinoline-4-one) in oral doses of 1×20 mg\\/kg, 1×50 mg\\/kg, 3×10 mg\\/kg and 3×25 mg\\/kg body weight (t=4 h) was tested in a complex study involving 36 healthy volunteers. In addition to the usual assessment of clinical chemistry, haematology, coagulation physiology, urinalysis, clinico-physiological examination including EEG, and medical examination, clinico-psychological parameters

  9. Cytokine Pattern of T Lymphocytes in Acute Schistosomiasis mansoni Patients following Treated Praziquantel Therapy

    PubMed Central

    Silveira-Lemos, Denise; Fernandes Costa-Silva, Matheus; Cardoso de Oliveira Silveira, Amanda; Azevedo Batista, Mauricio; Alves Oliveira-Fraga, Lúcia; Soares Silveira, Alda Maria; Barbosa Alvarez, Maria Carolina; Martins-Filho, Olindo Assis; Gazzinelli, Giovanni; Corrêa-Oliveira, Rodrigo; Teixeira-Carvalho, Andréa

    2013-01-01

    Acute schistosomiasis is associated with a primary exposure and is more commonly seen in nonimmune individuals traveling through endemic regions. In this study, we have focused on the cytokine profile of T lymphocytes evaluated in circulating leukocytes of acute Schistosomiasis mansoni-infected patients (ACT group) before and after praziquantel treatment (ACT-TR group). Our data demonstrated increased values of total leukocytes, eosinophils, and monocytes in both groups. Interestingly, we have observed that patients treated with praziquantel showed increased values of lymphocytes as compared with noninfected group (NI) or ACT groups. Furthermore, a decrease of neutrophils in ACT-TR was observed when compared to ACT group. Analyses of short-term in vitro whole blood stimulation demonstrated that, regardless of the presence of soluble Schistosoma mansoni eggs antigen (SEA), increased synthesis of IFN-? and IL-4 by T-cells was observed in the ACT group. Analyses of cytokine profile in CD8 T cells demonstrated higher percentage of IFN-? and IL-4 cells in both ACT and ACT-TR groups apart from increased percentage of IL-10 cells only in the ACT group. This study is the first one to point out the relevance of CD8 T lymphocytes in the immune response induced during the acute phase of schistosomiasis. PMID:23401741

  10. Artemether, artesunate, praziquantel and tribendimidine administered singly at different dosages against Clonorchis sinensis: a comparative in vivo study.

    PubMed

    Xiao, Shu-Hua; Jian, Xue; Tanner, Marcel; Yong-Nian, Zhang; Keiser, Jennifer; Utzinger, Jürg; Hui-Qiang, Qiang

    2008-04-01

    We comparatively assessed the in vivo efficacy of artemether, artesunate, praziquantel and tribendimidine against different stages of Clonorchis sinensis. Rats were infected with 40-50 C. sinensis metacercariae, and drugs were administered singly by the oral route at different dosages. Rats were dissected 2-4 weeks post-treatment and C. sinensis trematodes were removed from the liver and bile ducts and counted. We used a negative binomial regression model to test the effect of drug and dosage in terms of worm burden reduction. Single 150 mg/kg oral doses of artesunate, artemether, tribendimidine and praziquantel, administered to rats infected with adult C. sinensis, resulted in mean worm burden reductions of 100, 100, 89.5 and 80.7%, respectively (all P<0.001). Halving the dose to 75 mg/kg still resulted in highly significant worm burden reductions for artesunate, artemether and tribendimidine (71.4-100%), but not for praziquantel (20.7%). In the juvenile infection model, a single 150 mg/kg oral dose of tribendimidine and praziquantel resulted in mean worm burden reductions of 99.1 and 90.0%, respectively, whereas considerably lower reductions were observed for artemether (59.2%) and artesunate (57.6%) when used at the same single dose. The in vivo results presented here with the artemisinins and tribendimidine provide further data for clinical investigations to assess the safety and efficacy of these drugs in clonorchiasis patients. PMID:18308285

  11. [Efficacity of praziquantel in school-aged children in a hyperendemic zone for Schistoma haematobium (Niger, 1999)].

    PubMed

    Garba, A; Tohon, Z; Sidiki, A; Chippaux, J P; de Chabalier, F

    2001-03-01

    Urinary schistosomiasis is endemic in the Niger river valley. The aim of the present study was to assess the efficacy and side effects of a single oral dose of praziquantel at 40 mg/kg in the treatment of schistosomiasis. The investigation took place between April 5, 1999 and May 25, 1999. A total of 318 primary school children, aged from 6 to 16 years, of a Schistosoma haematobium endemic area were included in the survey. They underwent a macroscopic and parasitological examinations of the urine before treatment and two and six weeks after treatment. Treatment with praziquantel was given at 40 mg/kg of body weight in a single dose. Side effects due to praziquantel were assessed within the first 4 hours, and 24 hours after. Side effects were frequent (53.7%), especially occurring in the first four hours. Their expression was not associated with the sex of the child nor the intensity of the infestation. We noted that elder children expressed more complaints. The most frequent symptoms were abdominal pains, headaches and pruritus. All these signs were without gravity and resolved within the first twenty-four hours. Before treatment, the prevalence of infestation was 98%. Six weeks after treatment, 32% of children remained positive despite a marked reduction of egg excretion. In this survey, the side effects of the treatment were very frequent but without gravity. Using praziquantel, 68% of the subjects were cured completely. Urinary schistosomiasis control programs can continue to use it for mass treatment without risk. PMID:11346982

  12. Comparative clinical studies of nitazoxanide, albendazole and praziquantel in the treatment of ascariasis, trichuriasis and hymenolepiasis in children from Peru

    Microsoft Academic Search

    Juan Jave Ortiz; Nicholas Lopez Chegne; Gilles Gargala; Loic Favennec

    2002-01-01

    Three randomized clinical studies were conducted in 2000 to evaluate the efficacy of nitazoxanide paediatric suspension compared to albendazole in the treatment of ascariasis and trichuriasis and praziquantel in the treatment of hymenolepiasis in children from Cajamarca, Peru. Nitazoxanide was administered at a dose of 100 mg (age 1–3 years) or 200 mg (age 4–11 years) twice daily for 3

  13. Effect of artemether, artesunate, OZ78, praziquantel, and tribendimidine alone or in combination chemotherapy on the tegument of Clonorchis sinensis.

    PubMed

    Keiser, Jennifer; Vargas, Mireille

    2010-09-01

    We investigated the morphological effects of half-strength treatments with praziquantel, artemether, artesunate, OZ78 and tribendimidine as well as combinations of praziquantel with artemether, artesunate, OZ78 and tribendimidine and an artesunate-tribendimidine combination in rats harboring adult Clonorchis sinensis. Rats were infected with C. sinensis, dosed orally with single agents or combination treatments and flukes recovered at 3 or 5 days post-treatment. The number of flukes was counted, the viability recorded and surface changes monitored by scanning electron microscopy. Drug effects induced by the individual drugs at sub-curative doses 3 days post-treatment were minor with the exception of flukes recovered from rats treated with artemether and tribendimidine. Treatment with the praziquantel combinations of artesunate, OZ78 and tribendimidine did not produce a greater disruption of the tegument than the individual drugs 3 days post-treatment. On the other hand, at this time point many worms treated with artemether-praziquantel had died and eruptions, roughening or blebbing were observed on all worms examined. Five days post-treatment flukes exposed to any of the praziquantel combinations in rats had died. Rats treated with an artesunate-tribendimidine combination resulted in a rapid death of flukes, 3 days post-treatment all worms had been expelled. In conclusion, we have confirmed the promising clonorchicidal properties of different drug combinations in rats. Differences in the extent and time-scale of tegumental disruption have been observed. The effect of drug combinations against C. sinensis requires further scientific inquiry, e.g. in transmission electron microscopy studies and in the C. sinensis-rabbit model. PMID:20416396

  14. Toward Measuring Schistosoma Response to Praziquantel Treatment with Appropriate Descriptors of Egg Excretion

    PubMed Central

    Olliaro, Piero L.; Vaillant, Michel; Diawara, Aïssatou; Coulibaly, Jean T.; Garba, Amadou; Keiser, Jennifer; King, Charles H.; Knopp, Stefanie; Landouré, Aly; N’Goran, Eliézer K.; Raso, Giovanna; Scherrer, Alexandra U.; Sousa-Figueiredo, José Carlos; Stete, Katarina; Zhou, Xiao-Nong; Utzinger, Jürg

    2015-01-01

    Background The control of schistosomiasis emphasizes preventive chemotherapy with praziquantel, which aims at decreasing infection intensity and thus morbidity in individuals, as well as transmission in communities. Standardizing methods to assess treatment efficacy is important to compare trial outcomes across settings, and to monitor program effectiveness consistently. We compared customary methods and looked at possible complementary approaches in order to derive suggestions for standardizing outcome measures. Methodology/Principal Findings We analyzed data from 24 studies conducted at African, Asian, and Latin American sites, enrolling overall 4,740 individuals infected with Schistosoma mansoni, S. haematobium, or S. japonicum, and treated with praziquantel at doses of 40–80 mg/kg. We found that group-based arithmetic and geometric means can be used interchangeably to express egg reduction rates (ERR) only if treatment efficacy is high (>95%). For lower levels of efficacy, ERR estimates are higher with geometric than arithmetic means. Using the distribution of individual responses in egg excretion, 6.3%, 1.7% and 4.3% of the subjects treated for S. haematobium, S. japonicum and S. mansoni infection, respectively, had no reduction in their egg counts (ERR = 0). The 5th, 10th, and 25th centiles of the subjects treated for S. haematobium had individual ERRs of 0%, 49.3%, and 96.5%; the corresponding values for S. japonicum were 75%, 99%, and 99%; and for S. mansoni 18.2%, 65.3%, and 99.8%. Using a single rather than quadruplicate Kato-Katz thick smear excluded 19% of S. mansoni-infected individuals. Whilst the effect on estimating ERR was negligible by individual studies, ERR estimates by arithmetic means were 8% lower with a single measurement. Conclusions/Significance Arithmetic mean calculations of Schistosoma ERR are more sensitive and therefore more appropriate to monitor drug performance than geometric means. However, neither are satisfactory to identify poor responders. Group-based response estimated by arithmetic mean and the distribution of individual ERRs are correlated, but the latter appears to be more apt to detect the presence and to quantitate the magnitude of suboptimal responses to praziquantel. PMID:26086551

  15. CRIANÇAS DIANTE DAS CÂMERAS DE VIDEOCONFERÊNCIA: EXPERIMENTANDO A COMUNICAÇÃO VIA REDE EM UMA PRÉ-ESCOLA BRASILEIRA

    Microsoft Academic Search

    João Josué da Silva

    I. Introdução Nascemos seres biológicos e nos tornamos seres humanos através de um complexo processo social chamado educação. A educação é considerada, então o meio através do qual produz-se, em cada um de nós, a humanidade produzida ao longo da história pelo conjunto da humanidade e para o qual, ao mesmo tempo, contribuímos com a nossa elaboração individual dos fatos

  16. A INFLUÊNCIA DA RESPONSABILIDADE SOCIAL NOS HÁBITOS DE CONSUMO: uma análise do comportamento de consumo em universitários do curso de Administração com Habilitação em Marketing

    Microsoft Academic Search

    Ana Carolina; Saad Camargo; Ligia Ghisi

    RESUMO As mudanças na sociedade trouxeram ao consumidor um grande poder de decisão, tornando-o responsável pela escolha de seu consumo e preferências. As empresas para acompanharem tais mudanças apostaram em transformações e adaptaram-se aos novos rumos do mercado. O marketing por sua vez, vem inovando suas estratégias e ações para atender a essas novas necessidades e determinações do consumidor e

  17. Enhancement the oral bioavailability of praziquantel by incorporation into solid lipid nanoparticles.

    PubMed

    Yang, Li; Geng, Yehui; Li, Hao; Zhang, Yu; You, Jinsong; Chang, Yanyan

    2009-02-01

    The aim of this study was to assess the feasibility of solid lipid nanoparticles (SLN) to enhance the oral bioavailability of praziquantel (PZQ). SLN loaded with PZQ were produced by ultrasound technique. The characteristics of PZQ-SLN were studied in detail. The concentration of PZQ in plasma was determined using reversed-phase high-performance liquid chromatography after oral administration of PZQ-SLN and control PZQ tablets (PZQ-TAB) in rats respectively. The results showed that PZQ-SLN had an average diameter 110 nm with Zeta potential of -66.3 mV. The encapsulation efficiency of PZQ was about 80%. In vitro drug release fitted the Weibull distribution equation. There were two peaks in the PZQ concentration-time curves in plasma after oral administration of PZQ-SLN. The first peak might be caused by free drug and that adsorbed onto the surface of PZQ-SLN. The second peak was indicative of gut uptake of PZQ-SLN. The AUC(0-infinity) value of PZQ after oral administration of SLN was 4.1 fold higher than that obtained with the PZQ-TAB. The MRT of PZQ-SLN was also significantly enhanced, resulting in an about twofold increase compared with PZQ-TAB. Thus, the oral bioavailability of PZQ-SLN increased significantly compared to PZQ-TAB, and the results indicate that SLN can be a promising drug carrier for PZQ. PMID:19320279

  18. Propolis enhances the effectiveness of praziquantel in experimental schistosomiasis: biochemical and histopathological study.

    PubMed

    Mahmoud, Tamer Y; Rizk, Sherine M; Maghraby, Amany S; Shaheen, Amira A

    2014-12-01

    Despite the wide current use of praziquantel (PZQ) in treatment of schistosomiasis, low cure rates have been recorded in many studies. The aim of this study was directed to evaluate the curative effect of propolis (Pps) alone or in combination with PZQ on biochemical, immunological, parasitological, and histological changes associated with experimental schistosomiasis in mice. Schistosoma mansoni-infected mice were divided into two experimental sets, each with four subgroups: (i) untreated, (ii) treated with Pps/day p.o for 4 weeks, (iii) treated with PZQ p.o 2?×?500 mg/kg bd wt, and (iv) treated with Pps?+?PZQ as in group ii and iii; all treatments started on the 8th week postinfection, in addition to uninfected group as control for the previous groups. Treatment of infected mice with Pps, although failed to eradicate the worm, significantly reduced the hepatic granuloma number, their lymphocytic infiltration and aggregation, hepatic and splenic myeloperoxidase (MPO) activity and plasma, and liver and thymus nitric oxide (NOx) levels together with normalization of plasma proteins and alleviation of oxidative stress in the examined tissues as evidenced by reduction of malondialdehyde (MDA) and normalization of glutathione (GSH). Promising results were obtained when Pps was given in combination with PZQ, where the anti-schistosomal activity of PZQ was markedly potentiated with complete alleviation and amelioration of the histological and biochemical alteration associated with schistosomiasis. This study highlights the potential usefulness of Pps as an adjunct to PZQ in schistosomiasis. PMID:25266217

  19. Ca2+ channels and Praziquantel: a view from the free world

    PubMed Central

    Chan, John D.; Zarowiecki, Magdalena; Marchant, Jonathan S.

    2012-01-01

    Targeting the cellular Ca2+ channels and pumps that underpin parasite Ca2+ homeostasis may realize novel antihelmintic agents. Indeed, the antischistosomal drug praziquantel (PZQ) is a key clinical agent that has been proposed to work in this manner. Heterologous expression data has implicated an action of PZQ on voltage-operated Ca2+ channels, although the relevant in vivo target of this drug has remained undefined over three decades of clinical use. The purpose of this review is to bring new perspective to this issue by discussing the potential utility of free-living planarian flatworms for providing new insight into the mechanism of PZQ action. First, we discuss in vivo functional genetic data from the planarian system that broadly supports the molecular data collected in heterologous systems and the ‘Ca2+ hypothesis’ of PZQ action. On the basis of these similarities we highlight our current knowledge of platyhelminth voltage operated Ca2+ channels, their unique molecular pharmacology and the downstream functional PZQ interactome engaged by dysregulation of Ca2+ influx that has potential to yield novel antischistosomal targets. Overall the broad dataset underscore a common theme of PZQ-evoked disruptions of Ca2+ homeostasis in trematodes, cestodes and turbellarians, and showcase the utility of the planarian model for deriving insight into drug action and targets in parasitic flatworms. PMID:23246536

  20. In vitro and in vivo evaluation of praziquantel loaded implants based on PEG/PCL blends.

    PubMed

    Cheng, Liang; Lei, Lei; Guo, Shengrong

    2010-03-15

    In the present study, a series of praziquantel (PZQ) loaded implants based on PEG/PCL blends are fabricated by a combination of twin-screw mixing and hot-melt extrusion. In vitro drug release from these implants and the performance of the implants after implantation in rats are evaluated. XRD and DSC analysis results exhibit each component in the implants is mainly in its crystalline state. Dissolution test shows that the higher PEG content there is in the implants, the faster the drug will be released. Interestingly, PEG release from all implants is far faster than PZQ release, and complete PEG release occurs in 72 h. SEM result displays that after the in vitro drug release test, the cross-sections of implants with low PEG contents (0-5%) primarily consist of discrete pores; while those of implants with high PEG contents (10-30%) consist of interconnected pores or channels. The fitting results of drug release data with kinetic models reveal that PZQ release is governed by diffusion. After implantation, drug release becomes more moderate compared with in vitro drug release, and it tends to follow zero-order in the later stage. These results suggest that changing the composition of the PEG/PCL blends is an effective tool to adjust in vitro/in vivo drug release from the implants. PMID:20005928

  1. Transcriptional Responses of In Vivo Praziquantel Exposure in Schistosomes Identifies a Functional Role for Calcium Signalling Pathway Member CamKII

    PubMed Central

    You, Hong; McManus, Donald P.; Hu, Wei; Smout, Michael J.; Brindley, Paul J.; Gobert, Geoffrey N.

    2013-01-01

    Treatment for clinical schistosomiasis has relied centrally on the broad spectrum anthelmintic praziquantel; however, there is limited information on its mode of action or the molecular response of the parasite. This paper presents a transcriptional and functional approach to defining the molecular responses of schistosomes to praziquantel. Differential gene expression in Schistosoma japonicum was investigated by transcriptome-wide microarray analysis of adult worms perfused from infected mice after 0.5 to 24 hours after oral administration of sub-lethal doses of praziquantel. Genes up-regulated initially in male parasites were associated with “Tegument/Muscle Repair” and “Lipid/Ion Regulation” functions and were followed by “Drug Resistance” and “Ion Regulation” associated genes. Prominent responses induced in female worms included up-regulation of “Ca2+ Regulation” and “Drug Resistance” genes and later by transcripts of “Detoxification” and “Pathogen Defense” mechanisms. A subset of highly over-expressed genes, with putative drug resistance/detoxification roles or Ca2+-dependant/modulatory functions, were validated by qPCR. The leading candidate among these was CamKII, a putative calcium/calmodulin-dependent protein kinase type II delta chain. RNA interference was employed to knockdown CamKII in S. japonicum to determine the role of CamKII in the response to praziquantel. After partial-knockdown, schistosomes were analysed using IC50 concentrations (50% worm motility) and quantitative monitoring of parasite movement. When CamKII transcription was reduced by 50–69% in S. japonicum, the subsequent effect of an IC50 dosage of praziquantel was exacerbated, reducing motility from 47% to 27% in female worms and from 61% to 23% in males. These observations indicated that CamKII mitigates the effects of praziquantel, probably through stabilising Ca2+ fluxes within parasite muscles and tegument. Together, these studies comprehensively charted transcriptional changes upon exposure to praziquantel and, notably, identified CamKII as potentially central to the, as yet undefined, mode of action of praziquantel. PMID:23555262

  2. Efficacy of combined antiparasitic therapy with praziquantel and albendazole for neurocysticercosis: a double-blind, randomised controlled trial

    PubMed Central

    Garcia, Hector H; Gonzales, Isidro; Lescano, Andres G; Bustos, Javier A; Zimic, Mirko; Escalante, Diego; Saavedra, Herbert; Gavidia, Martin; Rodriguez, Lourdes; Najar, Enrique; Umeres, Hugo; Pretell, E Javier

    2014-01-01

    Summary Background Neurocysticercosis causes a substantial burden of seizure disorders worldwide. Treatment with either praziquantel or albendazole has suboptimum efficacy. We aimed to establish whether combination of these drugs would increase cysticidal efficacy and whether complete cyst resolution results in fewer seizures. We added an increased dose albendazole group to establish a potential effect of increased albendazole concentrations. Methods In this double-blind, placebo-controlled, phase 3 trial, patients with viable intraparenchymal neurocysticercosis were randomly assigned to receive 10 days of combined albendazole (15 mg/kg per day) plus praziquantel (50 mg/kg per day), standard albendazole (15 mg/kg per day), or increased dose albendazole (22·5 mg/kg per day). Randomisation was done with a computer generated schedule balanced within four strata based on number of cysts and concomitant antiepileptic drug. Patients and investigators were masked to group assignment. The primary outcome was complete cyst resolution on 6-month MRI. Enrolment was stopped after interim analysis because of parasiticidal superiority of one treatment group. Analysis excluded patients lost to follow-up before the 6-month MRI. This trial is registered with ClinicalTrials.gov, number NCT00441285. Findings Between March 3, 2010 and Nov 14, 2011, 124 patients were randomly assigned to study groups (41 to receive combined albendazole plus praziquantel [39 analysed], 43 standard albendazole [41 analysed], and 40 increased albendazole [38 analysed]). 25 (64%) of 39 patients in the combined treatment group had complete resolution of brain cysts compared with 15 (37%) of 41 patients in the standard albendazole group (rate ratio [RR] 1·75, 95% CI 1·10–2·79, p=0·014). 20 (53%) of 38 patients in the increased albendazole group had complete cyst resolution at 6-month MRI compared with 15 (37%) of 41 patients in the standard albendazole group (RR 1·44, 95% CI 0·87–2·38, p=0·151). No significant differences in adverse events were reported between treatment groups (18 in combined treatment group, 11 in standard albendazole group, and 19 in increased albendazole group). Interpretation Combination of albendazole plus praziquantel increases the parasiticidal effect in patients with multiple brain cysticercosis cysts without increased side-effects. A more efficacious parasiticidal regime without increased treatment-associated side-effects should improve the treatment and long term prognosis of patients with neurocysticercosis. Funding National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health. PMID:24999157

  3. Changes in specific anti-egg antibody levels following treatment with praziquantel for Schistosoma haematobium infection in children

    E-print Network

    Mutapi, Francisca

    with praziquantel at 40 mg/kg body weight. Levels of IgA, IgE, IgG1, IgG2, IgG3, IgG4, and IgM antibodies against in IgG1 levels and significant increases in IgE and IgG4 levels and significant decreases in IgA and IgG marked increase in IgG1 and (for older children) a more marked decrease in IgG2 levels. There were

  4. Solid lipid nanoparticle suspension enhanced the therapeutic efficacy of praziquantel against tapeworm

    PubMed Central

    Xie, Shuyu; Pan, Baoliang; Shi, Baoxin; Zhang, Zhuangzhi; Zhang, Xu; Wang, Ming; Zhou, Wenzhong

    2011-01-01

    Hydatid disease caused by tapeworm is an increasing public health and socioeconomic concern. In order to enhance the therapeutic efficacy of praziquantel (PZQ) against tapeworm, PZQ-loaded hydrogenated castor oil solid lipid nanoparticle (PZQ-HCO-SLN) suspension was prepared by a hot homogenization and ultrasonication method. The stability of the suspension at 4°C and room temperature was evaluated by the physicochemical characteristics of the nanoparticles and in-vitro release pattern of the suspension. Pharmacokinetics was studied after subcutaneous administration of the suspension in dogs. The therapeutic effect of the novel formulation was evaluated in dogs naturally infected with Echinococcus granulosus. The results showed that the drug recovery of the suspension was 97.59% ± 7.56%. Nanoparticle diameter, polydispersivity index, and zeta potential were 263.00 ± 11.15 nm, 0.34 ± 0.06, and ?11.57 ± 1.12 mV, respectively and showed no significant changes after 4 months of storage at both 4°C and room temperature. The stored suspensions displayed similar in-vitro release patterns as that of the newly prepared one. SLNs increased the bioavailability of PZQ 5.67-fold and extended the mean residence time of the drug from 56.71 to 280.38 hours. Single subcutaneous administration of PZQ-HCO-SLN suspension obtained enhanced therapeutic efficacy against tapeworm in infected dogs. At the dose of 5 mg/kg, the stool-ova reduction and negative conversion rates and tapeworm removal rate of the suspension were 100%, while the native PZQ were 91.55%, 87.5%, and 66.7%. When the dose reduced to 0.5 mg/kg, the native drug showed no effect, but the suspension still got the same therapeutic efficacy as that of the 5 mg/kg native PZQ. These results demonstrate that the PZQ-HCO-SLN suspension is a promising formulation to enhance the therapeutic efficacy of PZQ. PMID:22072873

  5. Inhibition or Knockdown of ABC Transporters Enhances Susceptibility of Adult and Juvenile Schistosomes to Praziquantel

    PubMed Central

    Kasinathan, Ravi S.; Sharma, Lalit Kumar; Cunningham, Charles; Webb, Thomas R.; Greenberg, Robert M.

    2014-01-01

    Parasitic flatworms of the genus Schistosoma cause schistosomiasis, a neglected tropical disease that affects hundreds of millions. Treatment of schistosomiasis depends almost entirely on the drug praziquantel (PZQ). Though essential to treating and controlling schistosomiasis, a major limitation of PZQ is that it is not active against immature mammalian-stage schistosomes. Furthermore, there are reports of field isolates with heritable reductions in PZQ susceptibility, and researchers have selected for PZQ-resistant schistosomes in the laboratory. P-glycoprotein (Pgp; ABCB1) and other ATP binding cassette (ABC) transporters remove a wide variety of toxins and xenobiotics from cells, and have been implicated in multidrug resistance (MDR). Changes in ABC transporter structure or expression levels are also associated with reduced drug susceptibility in parasitic helminths, including schistosomes. Here, we show that the activity of PZQ against schistosome adults and juveniles ex vivo is potentiated by co-administration of either the highly potent Pgp inhibitor tariquidar or combinations of inhibitors targeting multiple ABC multidrug transporters. Adult worms exposed to sublethal PZQ concentrations remain active, but co-administration of ABC transporter inhibitors results in complete loss of motility and disruption of the tegument. Notably, juvenile schistosomes (3–4 weeks post infection), normally refractory to 2 µM PZQ, become paralyzed when transporter inhibitors are added in combination with the PZQ. Experiments using the fluorescent PZQ derivative (R)-PZQ-BODIPY are consistent with the transporter inhibitors increasing effective intraworm concentrations of PZQ. Adult worms in which expression of ABC transporters has been suppressed by RNA interference show increased responsiveness to PZQ and increased retention of (R)-PZQ-BODIPY consistent with an important role for these proteins in setting levels of PZQ susceptibility. These results indicate that parasite ABC multidrug transporters might serve as important targets for enhancing the action of PZQ. They also suggest a potentially novel and readily-available strategy for overcoming reduced PZQ susceptibility of schistosomes. PMID:25330312

  6. Praziquantel in a Clay Nanoformulation Shows More Bioavailability and Higher Efficacy against Murine Schistosoma mansoni Infection.

    PubMed

    El-Feky, Gina S; Mohamed, Wael S; Nasr, Hanaa E; El-Lakkany, Naglaa M; Seif El-Din, Sayed H; Botros, Sanaa S

    2015-06-01

    Consideration of existing compounds always simplifies and shortens the long and difficult process of discovering new drugs specifically for diseases of developing countries, an approach that may add to the significant potential cost savings. This study focused on improving the biological characteristics of the already-existing antischistosomal praziquantel (PZQ) by incorporating it into montmorillonite (MMT) clay as a delivery carrier to overcome its known bioavailability drawbacks. The oral bioavailability of a PZQ-MMT clay nanoformulation and its in vivo efficacy against Schistosoma mansoni were investigated. The PZQ-MMT clay nanoformulation provided a preparation with a controlled release rate, a decrease in crystallinity, and an appreciable reduction in particle size. Uninfected and infected mice treated with PZQ-MMT clay showed 3.61- and 1.96-fold and 2.16- and 1.94-fold increases, respectively, in area under the concentration-time curve from 0 to 8 h (AUC0-8) and maximum concentration of drug in serum (Cmax), with a decrease in elimination rate constant (kel) by 2.84- and 1.35-fold and increases in the absorption rate constant (ka) and half-life (t1/2e) by 2.11- and 1.51-fold and 2.86- and 1.34-fold, respectively, versus the corresponding conventional PZQ-treated groups. This improved bioavailability has been expressed in higher efficacy of the drug, where the dose necessary to kill 50% of the worms was reduced by >3-fold (PZQ 50% effective dose [ED50] was 20.25 mg/kg of body weight for PZQ-MMT clay compared to 74.07 mg/kg for conventional PZQ), with significant reduction in total tissue egg load and increase in total immature, mature, and dead eggs in most of the drug-treated groups. This formulation showed better bioavailability, enhanced antischistosomal efficacy, and a safer profile despite the longer period of residence in the systemic circulation. Although the conventional drug's toxicity was not examined, animal mortality rates were not different between groups receiving the test PZQ-clay nanoformulation and conventional PZQ. PMID:25845870

  7. O TelEduc como recurso virtual de aprendizagem e apoio ao ensino presencial: relato de uma experiência de uso em um curso semi-presencial de Ensino Superior

    Microsoft Academic Search

    Italo Oscar; Riccardi Leon; Teresinha F. Nogueira

    Resumo: Nas atuais propostas educativas brasileiras há uma discussão vigente que está em andamento nos cursos de graduação e começa a destacar-se pelos diversos resultados qualitativos e possibilidades de aplicação no ensino superior. Trata-se do uso dos ambientes virtuais de aprendizagem (AVA) -concebidos como recursos tecnológicos ou ferramentas digitais de comunicação utilizados para mediar a aprendizagem- que podem complementar e\\/ou

  8. Evaluating the potential impact of mass praziquantel administration for HIV prevention in Schistosoma haematobium high-risk communities.

    PubMed

    Ndeffo Mbah, Martial L; Gilbert, Jennifer A; Galvani, Alison P

    2014-06-01

    Genital infection with Schistosoma haematobium is prevalent in sub-Saharan Africa. Epidemiological studies have observed that genital schistosomiasis is associated with an increased odd of HIV infection among women. We used mathematical modeling to explore the potential impact of mass preventive chemotherapy against schistosomiasis on HIV transmission in three sub-Saharan Africa countries: Angola, Kenya, and Zambia. We developed a model of female genital schistosomiasis (FGS) and HIV transmission dynamics, fitting it to data of HIV and S. haematobium prevalences as well as co-infection. We simulated targeted mass drug administration (MDA) with praziquantel to school-age children and mass treatment of the entire community. We estimated that, in S. haematobium high-risk communities, targeted annual treatment of school-age children could reduce HIV prevalence by 20% (95% CI: 12-31%) in Angola, 16% (95% CI: 10-32%) in Kenya, and 6% (95% CI: 3-18%) in Zambia after the first 20 years of intervention; and would reduce HIV incidence by 15% (95% CI: 13-32%) in Angola, 22% (95% CI: 18-42%) in Kenya, and 9% (95% CI: 3-22%) in Zambia. Extending the intervention to adults could reduce HIV prevalence by an additional 2.2% (95% CI: 0.2-12.0%) in Angola, 1.8% (95% CI: 0.1-5.2%) in Kenya, and 0.3% (95% CI: 0.1-2.1%) in Zambia; and would reduce HIV incidence by an additional 1.8% (95% CI: 0.0-14.4%) in Angola, 6.1% (95% CI: 0.5-12.6%) in Kenya, and 0.8% (95% CI: 0.0-2.7%) in Zambia. We showed that the exacerbation of HIV transmission due to FGS and the probability of developing FGS as a result of childhood infection with S. haematobium, were the most important factors in determining the effectiveness of praziquantel MDA for reducing HIV transmission. Praziquantel MDA may be an innovative measure for reducing schistosomiasis and HIV transmission in sub-Saharan Africa, the effectiveness of which varies with HIV prevalence. PMID:24928666

  9. Design and synthesis of molecular probes for the determination of the target of the anthelmintic drug praziquantel

    PubMed Central

    Sharma, Lalit Kumar; Cupit, Pauline M.; Goronga, Tino; Webb, Thomas R.; Cunningham, Charles

    2014-01-01

    Schistosomiasis is a highly prevalent neglected tropical disease caused by blood-dwelling helminths of the genus Schistosoma. Praziquantel (PZQ) is the only drug available widely for the treatment of this disease and is administered in racemic form, even though only the (R)-isomer has significant anthelmintic activity. Progress towards the development of a second generation of anthelmintics is hampered by a lack of understanding of the mechanism of action of PZQ. In this letter, we report an efficient protocol for the small-scale separation of enantiomers of 2(hydrolyzed PZQ) using supercritical fluid chromatography (SFC). The enantiopure 2 were then used to develop several molecular probes, which can potentially be used to help identify the protein target of PZQ and study its mode of action. PMID:24775301

  10. Efficacy of Emodepside/Praziquantel Spot-on (Profender®) against adult Aelurostrongylus abstrusus Nematodes in Experimentally Infected Cats.

    PubMed

    Böhm, Claudia; Wolken, Sonja; Schnyder, Manuela; Basso, Walter; Deplazes, Peter; Di Cesare, Angela; Deuster, Katrin; Schaper, Roland

    2015-08-01

    The adulticidal efficacy of a topical combination of emodepside 2.1 % (w/v) plus praziquantel 8.6 % (w/v) (Profender® spot-on for cats, Bayer) against adult Aelurostrongylus abstrusus nematodes was evaluated in two randomised, placebo-controlled laboratory efficacy studies. Each study involved 16 cats experimentally inoculated with L3 (800 and 600 each in studies no. 1 and 2, respectively) and randomised into two study groups of 8 cats each after onset of patency. While cats in the treatment group in study no. 1 received a single spot-on application at the minimum therapeutic dose (3 mg/kg emodepside and 12 mg/kg praziquantel), cats in study no. 2 were treated twice with an interval of 14 days. The faecal output of first stage larvae was monitored throughout the study. Necropsy was conducted 4 or 5 weeks after the (first) treatment and the worm counts were used for efficacy calculations. The control groups showed a geometric mean of the total worm count (live and dead worms) of 28.8 (study no. 1) and 17.6 (study no. 2), respectively. All control animals were infected. While the single treatment in study no. 1 resulted in a reduction of the total worm burden by 73.0 % (p = 0.0070), the treatment protocol in study no. 2 was 99.2 % effective (p = 0.0035). Based on live worm counts, the efficacy in study no. 2 was 100 % (p = 0.0030). It is concluded that two applications of Profender® spot-on given two weeks apart represent a safe and highly efficacious treatment regime against feline aelurostrongylosis. PMID:26152416

  11. Learning Astronomy by Playing in a Park. (Spanish Title: Aprender AstronoMía Jugando en Una Plaza.) Aprender Astronomia Brincando em Uma Praça

    NASA Astrophysics Data System (ADS)

    Camino, Néstor

    2012-12-01

    Some public-square games are presented in this paper, considered as didactic modules to help children imagine astronomical processes, based on the concept that learning in Astronomy should be developed to strengthen the relationship of our body with three-dimensional space and time, much in the same way we experience when observing the actual sky, holding a permanent "dialogue" between the actual world and what is to be learned. The games presented (merry-go-rounds and slides) were designed to work on the astronomical concepts related to the translation of the Earth around the Sun, the phases of the Moon and gravity, and on what is perceived by an observer about those phenomena. The description of each game, their physical and astronomical foundations, and a critical comment about their didactical importance are the key parts of the paper. Finally, a recommendation is given about the role teachers should play to be essential partners in the process of learning Astronomy by means of the interaction with these games. Se presentan en este trabajo algunos juegos de plaza, considerados como módulos didácticos para imaginar procesos astronómicos, a partir de la concepción de que el aprendizaje en Astronomía debe desarrollarse fortaleciendo la relación del propio cuerpo con el espacio tridimensional y con el tiempo, tal como se vive al observar el cielo, construyendo un "diálogo" entre el mundo real y los aprendizajes a construir. Los juegos presentados (calesitas y toboganes) fueron diseñados para trabajar sobre la traslación de la Tierra en torno al Sol, las fases de la Luna y la gravedad, y sobre lo que un observador percibe de los mismos. Se da la descripción de cada juego, se discuten sus fundamentos físicos y astronómicos, y se desarrolla una crítica didáctica de los mismos. Finalmente, se comenta el rol que deberían tener los docentes en el acompañamiento a los aprendices en el proceso de interacción con los juegos presentados. Apresentam-se neste trabalho alguns jogos de praça, considerados como módulos didáticos para imaginar processos astronômicos, a partir da concepção de que a aprendizagem em Astronomia deve-se desenvolver fortalecendo a relação do próprio corpo com o espaço tridimensional e com o tempo, tal como se vive ao observar o céu, construindo um "diálogo" entre o mundo real e as aprendizagens a construir. Os jogos apresentados (carrosséis e tobogãs) foram desenhados para trabalhar sobre a translação da Terra em torno do Sol, as fases da Lua e a gravidade, e sobre o que um observador percebe dos mesmos. Dá-se a descrição de cada jogo, discutem-se seus fundamentos físicos e astronômicos, e desenvolve-se uma crítica didática dos mesmos. Finalmente, comenta-se o papel que deveriam ter os docentes no apoio aos aprendizes no processo de interação com os jogos apresentados.

  12. Efficacy of Drontal ® Flavour Plus (50 mg praziquantel, 144 mg pyrantel embonate, 150 mg febantel per tablet) against Giardia sp in naturally infected dogs

    Microsoft Academic Search

    Ana Montoya; Diana Dado; Marta Mateo; Carmen Espinosa; Guadalupe Miró

    2008-01-01

    The therapeutic efficacy of praziquantel, pyrantel embonate and febantel (Drontal® Flavour Plus) for three and five consecutive\\u000a days was evaluated for treating naturally acquired giardiasis in dogs. In the study, 24 dogs naturally infected with Giardia were divided into three groups of eight dogs each. Dogs were treated at the recommended dosage for three or five consecutive\\u000a days, and a

  13. Prevention of Lactogenic Toxocara cati Infections in Kittens by Application of an Emodepside/Praziquantel Spot-on (Profender®) to the Pregnant Queen.

    PubMed

    Böhm, Claudia; Petry, Gabriele; Schaper, Roland; Wolken, Sonja; Strube, Christina

    2015-08-01

    This study aimed to evaluate the efficacy of an emodepside 2.1 % (w/v)/praziquantel 8.6 % (w/v) topical solution (ProfenderR spot-on for cats) in the prevention of lactogenic Toxocara cati infections. A controlled test was performed with two groups of 8 cats with confirmed pregnancy. All cats were infected with daily doses of 2000 T. cati eggs for 10 consecutive days starting 50 days post conception to produce an acute infection. Treatment was performed 60 days post conception. Queens in the treatment group received the emodepside/praziquantel solution at the minimum therapeutic dose (3 mg/kg emodepside and 12 mg/kg praziquantel), while the control group was treated with a placebo spot-on. Efficacy was evaluated 56 days post partum by necropsy of one randomly selected kitten of each litter and comparison of the worm burdens between the study groups. Additionally the necropsy results were supported by quantification of worms expelled with the faeces after deworming of the remaining kittens and all queens. The treatment in late pregnancy resulted in an efficacy of 98.7 % (p < 0.0001). All necropsied control kittens were infected (geometric mean 30.6). Seven of 8 kittens from treated mothers were free of T. cati (geometric mean 0.4). Worm counts after deworming reflected the results obtained at necropsy. No side effects of the treatment were observed. It is concluded that treatment with an emodepside/praziquantel spot-on solution during late pregnancy effectively prevents lactogenic transmission of T. cati to the offspring. The study design facilitated the generation of reliable data, while at the same time a minimum number of animals was sacrificed. PMID:26152418

  14. Light and electron microscopic studies on the effect of praziquantel on Schistosoma mansoni, Dicrocoelium dendriticum , and Fasciola hepatica (trematoda) in vitro

    Microsoft Academic Search

    B. Becker; H. Mehlhorn; P. Andrews; H. Thomas; J. Eckert

    1980-01-01

    The fine structure of the tegument of three trematode species,Schistosoma mansoni, Dicrocoelium dendriticum, andFasciola hepatica, was studied by means of light scanning (SEM) and transmission electron microscopy (TEM) after in vitro exposure to 0, 1,10, and 100 µg\\/ml of the anthelmintic praziquantel for 5, 15, 30, and 60 min. InS. mansoni andD. dendriticum the resulting vacuolization of the tegument was

  15. Increasing teacher motivation and supervision is an important but not sufficient strategy for improving praziquantel uptake in Schistosoma mansoni control programs: serial cross sectional surveys in Uganda

    PubMed Central

    2013-01-01

    Background Realization of the public health benefits of mass drug administration (MDA) for the control of schistosomiasis depends on achieving and maintaining high annual treatment coverage. In Uganda, the uptake of preventive treatment for schistosomiasis among school-age children in 2011 was only 28%. Strategies are needed to increase uptake. Methods Serial cross-sectional surveys were conducted at baseline (after MDA in 2011) and at follow-up MDA in 2012 where teacher motivation was provided and supervision strengthened in Jinja district of Uganda. Uptake of praziquantel was assessed in 1,010 randomly selected children from 12 primary schools during the baseline survey and in another set of 1,020 randomly selected children from the same primary schools during the follow-up survey. Results Self-reported uptake of praziquantel increased from 28.2% (95% CI 25.4%-30.9%) at baseline to 48.9% (95% CI 45.8%-52.0%) (p?praziquantel at baseline (49.8%, 95% CI 43.8%-55.8%) and at follow-up (46.6%, 95% CI 42%.1-51.2%) (p?=?0.50) as well as in the proportion of children with correct knowledge of schistosomiasis transmission and control between the baseline (45.9%, 95% CI 42.7%-73.7%) and follow-up (44.1%, 95% CI 41.0%- 47.2%) (p?=?0.42). Conclusion Although teacher motivation and supervision to distribute treatment increased the uptake of praziquantel among school-age children, the realized uptake is still lower than is recommended by the World Health Organization (WHO) and apparently too low to affect the prevalence and intensity of schistosomiasis among the children. Additional measures are needed to increase uptake of praziquantel if school-based MDA is to achieve the objective of preventive chemotherapy. PMID:24330594

  16. UMA ANÁLISE DO PERFIL DOS CONSUMIDORES DE PRODUTOS ORGÂNICOS EM PERNAMBUCO: O CASO DA FEIRA AGRO-ECOLÓGICA CHICO MENDES –RECIFE- PE

    Microsoft Academic Search

    Ana Maria Navaes Da Silva; Jose De Lima Albuquerque; Demorval Dos Santos Filho; Renata Patricia Leandro Do Nascimento; Elizandro Souza Da Silva

    2008-01-01

    A agricultura orgânica vem se destacando como umas das alternativas ao modo de produção agrícola convencional, o qual não atende mais aos padrões de consumo atuais devido a um aumento da degradação do meio ambiente, da contaminação do solo e do próprio agricultor que se expõe aos venenos utilizados nos processos de produção. Com isso, a agricultura orgânica aparece vinculada

  17. The first comprehensive study of praziquantel effects in vivo and in vitro on European liver fluke Opisthorchis felineus (Trematoda).

    PubMed

    Pakharukova, Mariya Y; Shilov, Alexander G; Pirozhkova, Darya S; Katokhin, Alexey V; Mordvinov, Viatcheslav A

    2015-07-01

    The European liver fluke Opisthorchis felineus (Rivolta, 1884) is an epidemiologically important parasite infecting mammals, including humans. Opisthorchis felineus is widespread in Russia, Kazakhstan and Eastern European countries. Praziquantel (PZQ) is the drug of choice for the treatment of opisthorchiasis, but the effects of this drug on O. felineus are poorly studied. The aims of this work were (i) to perform a study of PZQ effects in vitro, (ii) to identify morphological markers of PZQ action on O. felineus, (iii) to analyse damage to the worm surface and (iv) to assess the efficacy of PZQ in vivo in a hamster model. Light microscopy, optical sectioning and fluorescence microscopy were used to study morphological changes. In vivo, PZQ at a dose of 400mg/kg reduced the rate of infection in experimental acute and chronic opisthorchiasis in hamsters by 70% and 79%, respectively. In vitro, the drug caused destruction and vacuolisation of the tegument of O. felineus, contractions of the worm musculature, paralysis, and irreversible changes in morphology (IC50=0.14?g/mL). Differences in susceptibility to the drug between adult and newly excysted metacercariae were also observed. Qualitative effects of PZQ in vivo and in vitro were similar to the drug's effects on other trematodes, including epidemiologically important liver flukes. Nevertheless, high heterogeneity of O. felineus specimens in terms of susceptibility to the drug was observed. In addition, we describe for the first time the high rate of recovery of O. felineus following the destructive action of PZQ. PMID:25862308

  18. Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial.

    E-print Network

    Tweyongyere, Robert; Mawa, Patrice A; Kihembo, Macklyn; Jones, Frances M; Webb, Emily L; Cose, Stephen; Dunne, David W; Vennervald, Birgitte J; Elliott, Alison M

    2011-09-02

    Additional file 2. Levels of antibodies to schistosome worm (SWA) and egg (SEA) antigen in maternal blood at delivery, cord blood and infant blood at age one year, by praziquantel versus placebo treatment during pregnancy Levels of antibodies... to SWA Median (IQR) in µg/ml. Levels of antibodies to SEA Median (IQR) in µg/ml. Maternal levels at delivery Cord blood levels P-value* Maternal levels at delivery Cord blood responses* P-value* IgG1 Placebo group 104.7 (81.3, 116.8) 106.2 (52.0, 202...

  19. Efficacy of a novel topical fipronil, (S)-methoprene, eprinomectin and praziquantel combination against naturally acquired intestinal nematode and cestode infections in cats.

    PubMed

    Knaus, Martin; Abu-Madi, Marawan A; Ibarra-Velarde, Froylán; Kok, Dawie J; Kusi, Ilir; Postoli, Rezart; Chester, S Theodore; Rosentel, Joseph; Alva, Roberto; Irwin, Jennifer; Visser, Martin; Winter, Renate; Rehbein, Steffen

    2014-04-28

    The efficacy of a novel topical combination formulation of fipronil, (S)-methoprene, eprinomectin and praziquantel against naturally acquired intestinal nematode and cestode infections in cats was evaluated in seven negative control, blinded studies. Cats were selected based on a pre-treatment faecal examination indicating a patent infection with at least hookworms (two studies), Toxocara ascarids (one study), taeniid cestodes (two studies) or Dipylidium cestodes (two studies). In each study, cats were assigned randomly to blocks of two animals each, based on decreasing pre-treatment body weight and were randomly allocated to one of two groups of six to 12 cats: untreated (control) or treated with topical fipronil (8.3%, w/v), (S)-methoprene (10%, w/v), eprinomectin (0.4%, w/v) and praziquantel (8.3%, w/v) (BROADLINE(®), Merial) at 0.12 mL/kg body weight (providing a minimum of 10mg fipronil+12 mg S-methoprene+0.5mg eprinomectin+10mg praziquantel per kg body weight). The topical treatment was administered directly on the skin in the midline of the neck in a single spot once on Day 0. For parasite recovery and count, cats were euthanized humanely and necropsied seven or ten days after treatment. A single treatment with the novel topical combination product provided 91% efficacy against Ancylostoma braziliense, ? 99% efficacy against Ancylostoma tubaeforme, and >97% efficacy against Toxocara cati. Similarly, excellent efficacy was established against Taenia taeniaeformis, Dipylidium caninum and Diplopylidium spp. as demonstrated by >97% and up to 100% reductions of cestode counts in the treated cats when compared to the untreated controls (P<0.01). All cats accepted the treatment well based on health observations post-treatment and daily health observations. No adverse experiences or other health problems were observed throughout the studies. The results of this series of controlled studies demonstrated high efficacy and excellent acceptability of the novel topical combination formulation of fipronil, (S)-methoprene, eprinomectin and praziquantel against a broad range of feline intestinal nematode and cestode infections. PMID:24703071

  20. Ao judicial 930007202-1 j paga em fevereiro 10/02/2006 -2006 comea com mais uma boa notcia para um grupo de

    E-print Network

    Floeter, Sergio Ricardo

    correspondente ao período de férias), vantagens essas que deveriam ter sido pagas em até dois dias antes do ANADETE DE SOUZA PIROLO ANDRE LUIZ DIAS ANGELA OLINDA DALRI ANTONIO CARLOS DE FREITAS NORONHA ANTONIO PACHECO GREGORIO DIRCEIA PACHECO GREGORIO DJALMA DIAS FRANZONI DORIS DUTRA MORATO DORVALINO JORGE DA SILVA

  1. Efficacy in cats of a novel topical combination of fipronil, (S)-methoprene, eprinomectin, praziquantel, against induced infestations of Echinococcus multilocularis.

    PubMed

    Tielemans, Eric; Manavella, Coralie; Visser, Martin; Theodore Chester, S; Rosentel, Joseph

    2014-04-28

    Although foxes are the main reservoir of Echinococcus multilocularis, it is recognized that dogs and cats also may become infected. In cats the infection and egg production rates are usually low. Nevertheless, cats are a potential source of transmission of E. multilocularis. Due to the high human medical significance of E. multilocularis infection, it is important in endemic areas that owned cats are dewormed regularly. This paper presents the efficacy results of a new topical formulation, Broadline(®) (Merial) tested against E. multilocularis infection in cats. Two blinded laboratory studies were conducted to evaluate this novel topical combination of fipronil, (S)-methoprene, eprinomectin, and praziquantel against E. multilocularis. In each study, purpose-bred cats were assigned randomly to two treatment groups of 10 cats each: one untreated control group and one group treated at the minimum therapeutic dose of 0.12 mL/kg bodyweight to deliver 10mg fipronil, 12 mg (S)-methoprene, 0.5mg eprinomectin and 10mg praziquantel/kg bodyweight. The cats were inoculated orally with E. multilocularis protoscolices, 22 or 23 days before treatment. Based on necropsy and intestinal worm count, 8 or 11 days after treatment, the two studies confirmed 100% efficacy of Broadline(®) against adult E. multilocularis. PMID:24703072

  2. Efficacy and Safety of Different Dosages of Praziquantel for the Treatment of Schistosoma Japonicum: A Systematic Review and Meta-Analysis

    PubMed Central

    Cai, Damin; Zhang, Si; Wu, Julong; Wang, Xun; Wang, Meng; Lu, Xiaoling; Chen, Huiyu; Wang, Qian; Ma, Xingming

    2014-01-01

    Background: Praziquantel, an antischistosomal compound, is used as first-line drug for chemotherapy of Schistosoma japonicum since 1984. In this article, we conducted a systematic review and mete-analysis to evaluate the efficacy and safety of different dosages of praziquantel (PZQ) for treatment of Schistosoma japonicum. Evidence Acquisition: A number of six articles published in peer-reviewed journals before December 2012 were selected for analysis after searching the following literature databases: PubMed/Medline, the Chinese WanFang Literature Database, China National Knowledge Infrastructure (1994-2012.12), and the Chinese Biomedical Literature (1978-2012.12). Results: The meta-analyses showed that there is no statistically significant difference of the negative rate on the egg using 40 mg/kg compared to 60 mg/kg PZQ for S. japonicum treatment (RR 0.79, 95% CI 0.46 1.35; P < 0.39). The meta-analysis showed that there is no statistically significant difference of the side effects using 30 mg/kg compared with 40 mg/kg (RR 0.97, 95% CI 0.68 1.38; P = 0.87), 40 mg/kg compared with 60 mg/kg (RR 0.79, 95% CI 0.46 1.35; P = 0.39) and 50 mg/kg compared with 60 mg/kg (RR 0.89, 95% CI 0.56 1.42; P = 0.63). Conclusions: According to the results, there is no statistically significant difference in different doses of PZQ for treating S. japonicum. PMID:25558390

  3. Human IgG1 Responses to Surface Localised Schistosoma mansoni Ly6 Family Members Drop following Praziquantel Treatment

    PubMed Central

    Chalmers, Iain W.; Fitzsimmons, Colin M.; Brown, Martha; Pierrot, Christine; Jones, Frances M.; Wawrzyniak, Jakub M.; Fernandez-Fuentes, Narcis; Tukahebwa, Edridah M.; Dunne, David W.; Khalife, Jamal; Hoffmann, Karl F.

    2015-01-01

    Background The heptalaminate-covered, syncytial tegument is an important anatomical adaptation that enables schistosome parasites to maintain long-term, intravascular residence in definitive hosts. Investigation of the proteins present in this surface layer and the immune responses elicited by them during infection is crucial to our understanding of host/parasite interactions. Recent studies have revealed a number of novel tegumental surface proteins including three (SmCD59a, SmCD59b and Sm29) containing uPAR/Ly6 domains (renamed SmLy6A SmLy6B and SmLy6D in this study). While vaccination with SmLy6A (SmCD59a) and SmLy6D (Sm29) induces protective immunity in experimental models, human immunoglobulin responses to representative SmLy6 family members have yet to be thoroughly explored. Methodology/Principal Findings Using a PSI-BLAST-based search, we present a comprehensive reanalysis of the Schistosoma mansoni Ly6 family (SmLy6A-K). Our examination extends the number of members to eleven (including three novel proteins) and provides strong evidence that the previously identified vaccine candidate Sm29 (renamed SmLy6D) is a unique double uPAR/Ly6 domain-containing representative. Presence of canonical cysteine residues, signal peptides and GPI-anchor sites strongly suggest that all SmLy6 proteins are cell surface-bound. To provide evidence that SmLy6 members are immunogenic in human populations, we report IgG1 (as well as IgG4 and IgE) responses against two surface-bound representatives (SmLy6A and SmLy6B) within a cohort of S. mansoni-infected Ugandan males before and after praziquantel treatment. While pre-treatment IgG1 prevalence for SmLy6A and SmLy6B differs amongst the studied population (7.4% and 25.3% of the cohort, respectively), these values are both higher than IgG1 prevalence (2.7%) for a sub-surface tegumental antigen, SmTAL1. Further, post-treatment IgG1 levels against surface-associated SmLy6A and SmLy6B significantly drop (p = 0.020 and p < 0.001, respectively) when compared to rising IgG1 levels against sub-surface SmTAL1. Conclusions/Significance Collectively, these results expand the number of SmLy6 proteins found within S. mansoni and specifically demonstrate that surface-associated SmLy6A and SmLy6B elicit immunological responses during infection in endemic communities. PMID:26147973

  4. UMA EXPERIÊNCIA COM O PROJETO MANHATTAN NO ENSINO FUNDAMENTAL An experience with the Manhattan Project in the Elementary School

    Microsoft Academic Search

    Rafaela Samagaia; Luiz O. Q. Peduzzi

    Resumo: O presente artigo discute uma dissertação de mestrado que utilizou uma perspectiva educacio- nal voltada à formação de cidadãos e defendida na proposta de Edgar Morin e no relatório da UNESCO sobre educação para o século XXI. Para isso, aborda a importância de uma nova prática escolar, preocupa- da em manter o estudante como centro das atividades em sala

  5. Treatment of schistosomiasis in African infants and preschool-aged children: downward extension and biometric optimization of the current praziquantel dose pole

    PubMed Central

    Sousa-Figueiredo, José C.; Betson, Martha; Stothard, J. Russell

    2012-01-01

    Summary To facilitate administration of praziquantel (PZQ) to African infants and preschool-aged children using a dose pole, the performance of two downwardly extended versions (the first created in 2010 using biometric data from Uganda alone and the second version created here using data from 36 countries) was assessed against height/weight data from a total of 166 210 preschool-aged children (?6 year olds) from 36 African countries. New and optimized thresholds for PZQ tablet administration at one tablet (600 mg), ¾ and ½ tablet divisions are suggested here. Both dose poles investigated estimated an acceptable PZQ dosage (30–60 mg/Kg) for more than 95% of children. Extension and optimization of the current PZQ dose pole, followed by theoretical validation using biometric data from preschool-aged children (0–6 years of age, 60–110 cm in height) from 36 African countries will help future mass drug administration campaigns incorporate younger children. This newly optimized dose pole with single 600 mg (height: 99–110 cm), ¾ (height: 83–99 cm) and ½ (height: 66–83 cm) tablet divisions, also reduces drug waste and facilitates inclusion of preschool-aged children. Our findings also have bearings on the use of other dose poles for treatment of young children. PMID:22876272

  6. Antischistosomal effects of praziquantel, its alkaline hydrolysis and sun decomposed products on experimentally S. mansoni infected albino mice. (A) Efficacy assessment based on clinicopathological findings.

    PubMed

    Suleiman, M I; Akarim, E I; Ibrahim, K E E; Saad, A M; Mohammed, A E; Ahmed, B M; Sulaiman, S M

    2004-04-01

    The antischistosomal activity of praziquantel (PZQ), its alkaline hydrolysis product (HP) and its sun-decomposed (SD) products was investigated in S. mansoni experimentally infected mice. The evaluation was made depending on the degree of clinico-pathological changes. The results obtained revealed that, PZQ, HP and the SD have induced partial suppression of worm fecundity as judged by the significant reduction in eggs per gram of faeces in comparison with the infected untreated control. The effect on tissue egg deposition in the treated groups was comparable to the infection of untrea ted control. Worm recovery showed large reduction in the number of worms for SD (47.6%) and HP (28.6%) compared to PZQ (16.6%) treated groups. So, the former two compounds have the superior antischistosomal activities. Glutamate pyruvate transominase (GPT) and glutamate oxaloacetate transaminase (GOT) concentrations were measured. The GOT values for all treated groups were significantly higher than those for the healthy control group (p=0.01). The SD group enzyme concentration was even higher than the infected untreated control. The GPT values of all groups were greater than the uninfected control and the difference was significant for the infected untreated, PZQ and the SD treated groups (p=0.05). PMID:15143740

  7. Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel against induced infections of Ancylostoma spp. nematodes of cats.

    PubMed

    Prullage, Joseph B; Knaus, Martin; Bowman, Dwight D; Chester, S Theodore; Visser, Martin; Rehbein, Steffen; Rosentel, Joseph

    2014-04-28

    Four studies were conducted to examine the efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin, and praziquantel (BROADLINE(®), Merial) against Ancylostoma tubaeforme and Ancylostoma braziliense hookworms of cats. In each study, purpose-bred cats were randomly assigned to treatment groups of 10 or 12 cats per group. In three studies the cats were inoculated with A. tubaeforme and in one study with A. braziliense. The inoculations were undertaken on a schedule which resulted in the hookworms reaching the fourth larval stage in two of the studies, or the adult stage in four of the studies, by the day of treatment. In each study there was also an untreated control and 1 or 2 groups treated with the novel combination. In the two studies where efficacy against the fourth larval stage of A. tubaeforme was tested, the efficacy recorded was 100%. In the three studies where efficacy against the adult stage of A. tubaeforme was tested, efficacy of 100% was also confirmed. In the study where efficacy against the adult stage of A. braziliense was tested efficacy was 99.5%. PMID:24703073

  8. Urine heme dipsticks are useful in monitoring the impact of Praziquantel treatment on Schistosoma haematobium in sentinel communities of Delta State, Nigeria

    PubMed Central

    Emukah, Emmanuel; Gutman, Julie; Eguagie, John; Miri, Emmanuel S; Yinkore, Paul; Okocha, Ndudi; Jibunor, Victoria; Obiageli, Nebe; Ikenna, Nwoye Augustine; Richards, Frank O.

    2012-01-01

    Nigeria is highly endemic for infection with Schistosoma haematobium, which most commonly manifests itself with blood in urine. To monitor the impact of annual mass drug administration (MDA) with praziquantel for S. haematobium in Delta State, Nigeria, cross-sectional hematuria surveys of school children were conducted in 8 sentinel villages (SVs) at baseline (n=240) and after two annual doses (n=402). We assessed the comparability of three assessments of hematuria (child’s reported history, nurse visual diagnosis (NVD) and dipstick) to determine the need for mass treatment. Dipstick was considered to be the gold standard. Prior to treatment, history and NVD each identified only the 3 most highly prevalent SVs, and overall this represented just 37.5% of the 8 SVs in need of treatment. Following treatment, after dipstick prevalence decreased by 88.5% (p<0.001), and history and NVD identified only one of two villages still needing treatment. The study suggests that dipsticks should be the recommended method for launching and monitoring mass treatment for S. haematobium. PMID:22245148

  9. Efficacy of Drontal Flavour Plus (50 mg praziquantel, 144 mg pyrantel embonate, 150 mg febantel per tablet) against Giardia sp in naturally infected dogs.

    PubMed

    Montoya, Ana; Dado, Diana; Mateo, Marta; Espinosa, Carmen; Miró, Guadalupe

    2008-10-01

    The therapeutic efficacy of praziquantel, pyrantel embonate and febantel (Drontal Flavour Plus) for three and five consecutive days was evaluated for treating naturally acquired giardiasis in dogs. In the study, 24 dogs naturally infected with Giardia were divided into three groups of eight dogs each. Dogs were treated at the recommended dosage for three or five consecutive days, and a control group remained untreated. Faecal samples from each dog were submitted to coprological examination from day-4 to -2 and at days 5, 7, 9 and 11. Faecal consistency was also assessed daily to study end. All dogs in the control group remained positive until study end. Giardia cysts were not detected in faeces of six of the eight dogs in the group treated on three consecutive days, and in faeces of five of the dogs in the group treated on five consecutive days. Unformed to diarrhoeic faeces were more often reported in dogs in the untreated control group than in dogs in both treatment groups. Efficacy of treatment for five consecutive days was not statistically better than treatment for three consecutive days. PMID:18661153

  10. Inovações educacionais: uma experiência de educação ambiental no Parque São Bartolomeu - Salvador, Bahia, Brasil

    Microsoft Academic Search

    Maria Alba Guedes Machado Mello

    2007-01-01

    O texto apresenta uma experiência de Educação Ambiental em nove escolas da rede pública municipal de Salvador-Bahia, Brasil, desenvolvida mais intensivamente durante os anos de 1994 a 1997 e coordenada pela ong, Centro de Educação Ambiental São Bartolomeu-CEASB, em convênio com a Prefeitura Municipal e associações do bairro. Tratada como uma questão ética, a Educação Ambiental tem como objeto pedagógico

  11. [Long-term impact of a mass treatment by praziquantel on morbidity due to Schistosoma haematobium in two hyperendemic villages of Niger].

    PubMed

    Garba, A; Campagne, G; Tassie, J M; Barkire, A; Vera, C; Sellin, B; Chippaux, J P

    2004-02-01

    Although it is established that the treatment by praziquantel reduces the urinary lesions due to Schistosoma haematobium, the frequency of mass treatment necessary to maintain a low morbidity level remains poorly known. The objective of this work was to study the impact over three years of a single praziquantel mass treatment on schistosomiasis morbidity in two different systems of disease transmission in Niger. The study was performed in 2 villages hyperendemic for schistosomiasis in the South-West of Niger presenting respectively 2 different systems of schistosomiasis transmission: Koutoukalé-Zéno (K Zéno), located close to an irrigated area of the Niger River Valley where the transmission is permanent, and Téguey located along a temporary pond where the transmission is seasonal. After the initial evaluation (1994), we carried out a survey 3 years later (1997) except in K. Zéno where an intermediate evaluation was performed 10 months after the initial survey (1995). Approximately 300 randomised people have been examined as follows: macroscopic examination of urine and reagent sticks for macro- and micro-haematuria, filtration and microscopic examination of urine for Schistosoma eggs, and ultrasound scan of the urinary tract for morbidity. The therapeutic coverage has reached 69.9% in K. Zéno and 78.2% in Téguey. The prevalence of infestation decreased from 74.1% to 56.4 % in K. Zéno (p < 0.001) and from 65.3% to 30.4% in Téguey (p < 0.001) at the end of the 3 years. The prevalence of heavy infestation (eggs > or = 50) went in the same time from 9.9% to 12.8% (p = 0.3) in K. Zéno and from 9.1% to 3.3% in Téguey (p = 0.01). Using ultrasound scan, the prevalence of the bladder lesions reached its previous level in both villages. However the prevalence of hydronephrosis decreased from 21.1% to 3.9% in K. éno (p < 0.001) and from 12.6% to 4.2% in Téguey (p < 0.001). Three years after the single mass treatment, the morbidity did not reach the initial level. The effectiveness of the treatment is better in the pond system where the transmission is seasonal. The lesions of the upper tract decreased more slowly than the bladder lesions, but a long time after the treatment. The re-infestation induced the re-appearance of the bladder lesions sooner than the lesions of the upper tract. The periodicity of the treatment should be variable according to the transmission system. It should occur every 2 years in irrigated areas and could be delayed (3 years) in temporary ponds. The control was beneficial in the pond system and induced a significant reduction of the severe lesions. PMID:15104149

  12. A Latent Markov Modelling Approach to the Evaluation of Circulating Cathodic Antigen Strips for Schistosomiasis Diagnosis Pre- and Post-Praziquantel Treatment in Uganda

    PubMed Central

    Koukounari, Artemis; Donnelly, Christl A.; Moustaki, Irini; Tukahebwa, Edridah M.; Kabatereine, Narcis B.; Wilson, Shona; Webster, Joanne P.; Deelder, André M.; Vennervald, Birgitte J.; van Dam, Govert J.

    2013-01-01

    Regular treatment with praziquantel (PZQ) is the strategy for human schistosomiasis control aiming to prevent morbidity in later life. With the recent resolution on schistosomiasis elimination by the 65th World Health Assembly, appropriate diagnostic tools to inform interventions are keys to their success. We present a discrete Markov chains modelling framework that deals with the longitudinal study design and the measurement error in the diagnostic methods under study. A longitudinal detailed dataset from Uganda, in which one or two doses of PZQ treatment were provided, was analyzed through Latent Markov Models (LMMs). The aim was to evaluate the diagnostic accuracy of Circulating Cathodic Antigen (CCA) and of double Kato-Katz (KK) faecal slides over three consecutive days for Schistosoma mansoni infection simultaneously by age group at baseline and at two follow-up times post treatment. Diagnostic test sensitivities and specificities and the true underlying infection prevalence over time as well as the probabilities of transitions between infected and uninfected states are provided. The estimated transition probability matrices provide parsimonious yet important insights into the re-infection and cure rates in the two age groups. We show that the CCA diagnostic performance remained constant after PZQ treatment and that this test was overall more sensitive but less specific than single-day double KK for the diagnosis of S. mansoni infection. The probability of clearing infection from baseline to 9 weeks was higher among those who received two PZQ doses compared to one PZQ dose for both age groups, with much higher re-infection rates among children compared to adolescents and adults. We recommend LMMs as a useful methodology for monitoring and evaluation and treatment decision research as well as CCA for mapping surveys of S. mansoni infection, although additional diagnostic tools should be incorporated in schistosomiasis elimination programs. PMID:24367250

  13. Comparative in vivo antioxidant levels in Schistosoma mansoni infected mice treated with praziquantel or the essential oil of Melaleuca armillaris leaves.

    PubMed

    Rizk, M; Ibrahim, N; El-Rigal, N

    2012-10-15

    Plant extracts are continuously investigated for their extensive inclusion of biologically active constituents that exert therapeutic activities against many diseases. The aim of this study was to assess the antioxidant/anti-schistosomal activities of the essential oil of the fresh leaves of Melaleuca armillaris (M. armillaris) compared to Praziquantel (PZQ) on normal and Schistosoma mansoni-infected mice. The oil was isolated by hydrodistillation and analyzed by gas chromatography/mass spectrometry (GC/MS). The oil was rich in 1,8-cineole (33.93%), terpinen-4-ol (18.79%), limonene (10.37%) and B-pinene (6.59%). M. armillaris oil (150 mg kg(-1), orally) was administered from the second week post infection twice per week for six weeks. PZQ (500 mg kg(-1), orally) was administered for two successive days 8 weeks post infection and mice sacrificed one week later. Total protein, Malondialdehyde (MDA), Glutathione (GSH), vitamins C and E, the antioxidant enzymes catalase and superoxide dismutase, as well as liver weights and liver/body weight were determined in the liver tissues. Results showed that, both treatments significantly ameliorated the disturbed levels ofGSH and MDA in infected mice. Both vitamins were significantly elevated after treatment with the oil while a significant increase in catalase accompanied by a pronounced decrease in SOD were obtained after treatment with PZQ. Both treatments markedly improved liver and body weights in infected mice compared to the infected-untreated ones. In conclusion, natural plant sources may be used as promising alternative agents to chemical drugs for schistosomiasis treatment, since the latter may result in drug-induced resistance arising from repeated use. PMID:24199475

  14. Factors associated with coverage of praziquantel for schistosomiasis control in the community-direct intervention (CDI) approach in Mali (West Africa)

    PubMed Central

    2013-01-01

    Background Despite the progress made in the control of Neglected Tropical Diseases (NTD), schistosome and soil-transmitted helminth infections are far from being effectively managed in many parts of the world. Chemotherapy, the key element of all control strategies, is faced with some difficulties in terms of access to treatment. Our study aims to describe the factors involved in the success or failure of the community-directed intervention (CDI) approach through control programmes, which aims to achieve consistent high coverage at affordable and sustainable costs in endemic areas. Methods The CDI approach was carried out from December 2007 to October 2008 in ten villages of the district of Diéma, Mali. At inclusion, each child part of the study’s sample was interviewed and submitted for a physical examination. The study focused on: data collection, treatment of the eligible population, evaluation of the treatment coverage, performance of community drug distributors (CDDs), and the involvement and perception of populations. Results A total of 8,022 eligible people were studied with a mean coverage rate of 76.7%. Using multiple regression, it was determined that receiving praziquantel as treatment was associated with five factors: belonging to the Fulani or Moorish ethnic minority versus the Bambara/Soninke, use of the central versus the house-to-house drug distribution mode, the ratio of the population to the number of CDDs, the lack of supervision and belonging to the age group of 15 years or above (p<0.05). As well as that, it was found that the presence of parallel community-based programmes (HIV, tuberculosis) that provide financial incentives for community members discouraged many CDDs (who in most cases are volunteers) to participate in the CDI approach due to a lack of incentives. Conclusions The findings indicate that the success of the CDI approach depends on, amongst other things, the personal characteristics of the respondents, as well as on community factors. PMID:23849481

  15. Chords: Em 022000 Em Em Em Em C C C C

    E-print Network

    Reiners, Peter W.

    Verse 1 Chorus Verse 2 Chorus Verse 3 Chords: Em 022000 C 035553 G 320002 F 133211 Intro: Em Em Em Em C C C C Em Em Em Em C C C C Em Em Em Em C C C C Em Em Em Em C C C C Verse: Em Em Em Em C C C C G G G G G G G G Em Em Em Em C C C C G G G G G G G G Em Em Em Em C C C C G G G G G G G G Em Em Em Em C C

  16. ISSN 0103-9741 Monografias em Cincia da Computao

    E-print Network

    Endler, Markus

    Sistema de recomendação: uma abordagem por ltro colaborativo baseado em modelos 1 Dárlinton Barbosa FeresPUC ISSN 0103-9741 Monografias em Ciência da Computação n 19/10 Sistemas de Recomendação: uma abordagem por filtro colaborativo baseado em modelos Dárlinton Barbosa Feres Carvalho Ruy Luiz Milidiú

  17. Single Versus Double Dose Praziquantel Comparison on Efficacy and Schistosoma mansoni Re-Infection in Preschool-Age Children in Uganda: A Randomized Controlled Trial

    PubMed Central

    Nalugwa, Allen; Nuwaha, Fred; Tukahebwa, Edridah Muheki; Olsen, Annette

    2015-01-01

    Background Schistosoma mansoni infection is proven to be a major health problem of preschool-age children in sub-Saharan Africa, yet this age category is not part of the schistosomiasis control program. The objective of this study was to compare the impact of single and double dose praziquantel (PZQ) treatment on cure rates (CRs), egg reduction rates (ERRs) and re-infection rates 8 months later, in children aged 1-5 years living along Lake Victoria, Uganda. Methodology/Principal Findings Infected children (n= 1017) were randomized to receive either a single or double dose of PZQ. Initially all children were treated with a single standard oral dose 40 mg/kg body weight of PZQ. Two weeks later a second dose was administered to children in the double dose treatment arm. Side effects were monitored at 30 minutes to 24 hours after each treatment. Efficacy in terms of CRs and ERRs for the two treatments was assessed and compared 1 month after the second treatment. Re-infection with S. mansoni was assessed in the same children 8 months following the second treatment. CRs were non-significantly higher in children treated with two 40 mg/kg PZQ doses (85.5%; 290/339) compared to a single dose (83.2%; 297/357). ERRs were significantly higher in the double dose with 99.3 (95%CI: 99.2-99.5) compared with 98.9 (95%CI: 98.7-99.1) using a single dose, (P = 0.01). Side effects occurred more frequently during the first round of drug administration and were mild and short-lived; these included vomiting, abdominal pain and bloody diarrhea. Overall re-infection rate 8 months post treatment was 44.5%. Conclusions PZQ is efficacious and relatively safe to use in preschool-age children but there is still an unmet need to improve its formulation to suit small children. Two PZQ doses lead to significant reduction in egg excretion compared to a single dose. Re-infection rates with S. mansoni 8 months post treatment is the same among children irrespective of the treatment regimen. PMID:26011733

  18. Chemical Compatibility and Safety of Imidacloprid/Flumethrin Collar (Seresto(®)) Concomitantly Used with Imidacloprid/Moxidectin (Advocate (®), Advantage (®) Multi) and Emodepside/Praziquantel (Profender (®)) Spot-on Formulations.

    PubMed

    Krüdewagen, Eva Maria; Remer, Carolin; Deuster, Katrin; Schunack, Bettina; Wolken, Sonja; Crafford, Dionne; Fourie, Josephus; Stanneck, Dorothee

    2015-08-01

    Safety of concomitant use of veterinary products is of clinical interest. A series of studies was performed to evaluate the chemical compatibility and short term dermal and systemic safety of an imidacloprid/flumethrin collar (Seresto(®)/ Foresto(®), Bayer) used concomitantly with spot-on or tablet formulations.Chemical compatibility was evaluated in-vitro (study reference A) on collar pieces, followed by two small, non-controlled clinical studies (study reference B) in both, cats and dogs. The studies showed, that certain solvents affected the collar in-vitro, but not in their marketed formulations.Dermal and systemic safety of different spot-on or tablet formulations was first evaluated in a small, non-controlled clinical study (study reference C) in cats and dogs, via clinical observations only, followed by controlled clinical safety studies of concomitant use with imidacloprid/ moxidectin (Advocate(®)/ Advantage(®) Multi, Bayer) in dogs and cats (study reference D) and emodepside/ praziquantel (Profender(®), Bayer) in cats (study reference E), assessing safety aspects by clinical observations and statistical analyses of hematology and clinical chemistry parameters compared to baseline values and between treated and control groups.Dermal safety findings over all clinical studies (study references B to E) matched those already described for the respective products and included transient cosmetic changes (oily hair and crystal formation) at the site of spot-on application and broken hair, transient alopecia and skin alterations at the site of collar application. There were no indications of these findings aggravating under the conditions of concurrent use. There were no systemic safety findings of clinical significance in any of the clinical safety studies (study reference C to E). Assessment of blood parameters revealed some deviations from baseline levels and from the reference range in dogs as well as in cats, but no clinical relevance could be deduced. Hematology and clinical chemistry results confirmed the safety of the concomitant treatment. It is concluded that Seresto(®) is chemically compatible with solvents used in major spot-on formulations on the market and is dermally and systemically safe for adult dogs and cats when used concomitantly with Advocate(®) and Profender(®) spot-on formulations. PMID:26152409

  19. Cosmoeducação: uma proposta para o ensino de astronomia

    NASA Astrophysics Data System (ADS)

    Medeiros, L. A. L.; Jafelice, L. C.

    2003-08-01

    Entende-se por cosmoeducação o desenvolvimento vivencial da unidade homem-cosmo. Este conceito é norteado pela psicologia transpessoal, que estuda o ser humano em sua totalidade, onde suas relações ecológicas e cósmicas são de grande importância. Constata-se uma necessidade latente no ser humano moderno em resgatar uma relação holística com o Universo. Neste trabalho exploramos meios de cultivar a consciência de que o ser humano constitui parte integrante do cosmo e se relaciona com este com o objetivo de promover em si uma percepção ambiental mais ampla. Nossa hipótese de trabalho inicial foi que o ensino de conteúdos básicos em astronomia realizado através de uma abordagem holística, que incorpore práticas vivenciais correlacionadas àqueles conteúdos, pode despertar no indivíduo sua identidade cósmica. O método que utilizamos é o fenomenológico e o universo desta pesquisa é um grupo de estudantes da disciplina de Astronomia (Curso de Licenciatura em Geografia/UFRN), onde realizamos observação participante, entrevistas, depoimentos e as práticas vivenciais mencionadas. Neste caso estamos desenvolvendo e adaptando exercícios de algumas técnicas terapêuticas de psicologia transpessoal, que um de nós (LALM) tem aplicado no contexto clínico, para trabalhar aspectos cognitivos envolvidos naquele processo de conscientização cósmica. Resultados parciais claramente referendam a hipótese inicial. Um resultado a destacar é fruto de uma dinâmica de representação corporal interiorizada do eclipse lunar, envolvendo um pequeno grupo daqueles estudantes, na qual conteúdos míticos afloraram de maneira espontânea e contundente para todos, sugerindo ressonância, ou pelo menos isomorfismo, entre o macro e o microcosmo. Este e outros resultados são discutidos em detalhe neste trabalho. (PPGECNM/UFRN; PRONEX/FINEP; NUPA/USP; Temáticos/FAPESP).

  20. Psiquiatria baseada em evidências

    Microsoft Academic Search

    Maurício S de Lima; Bernardo GO Soares; Josué Bacaltchuk

    2000-01-01

    Abstract Keywords Em psiquiatria, observa-se grande variabilidade de práticas clínicas, muitas vezes desnecessária. Essas varia- ções podem,estar relacionadas à ausência de evidência científica confiável ou ao desconhecimento,das evidên- cias de boa qualidade disponíveis. A medicina baseada em evidências (MBE) é uma combinação de estratégias que busca assegurar que o cuidado individual do paciente seja baseado na melhor informação disponível, a

  1. Efficacy against nematode and cestode infections and safety of a novel topical fipronil, (S)-methoprene, eprinomectin and praziquantel combination product in domestic cats under field conditions in Europe.

    PubMed

    Rehbein, Steffen; Capári, Balazs; Duscher, Georg; Keidane, Dace; Kirkova, Zvezdelina; Petkevi?ius, Saulius; Rapti, Dhimiter; Wagner, Annegret; Wagner, Thomas; Chester, S Theodore; Rosentel, Joseph; Tielemans, Eric; Visser, Martin; Winter, Renate; Kley, Katrin; Knaus, Martin

    2014-04-28

    A novel topical combination product (BROADLINE(®), Merial) composed of fipronil, (S)-methoprene, eprinomectin and praziquantel was evaluated for safety and efficacy against nematode and cestode infections in domestic cats. The study comprised a multi-centre, positive control, blinded, field study, using a randomized block design based on order of presentation for allocation. In total 196 client-owned cats, confirmed as positive for naturally acquired infections of nematodes and/or cestodes by pre-treatment faecal examination, were studied in seven countries in Europe. Pre-treatment faecal examination revealed the presence of Toxocara, hookworm, Capillaria and/or spirurid nematode infections in 129, 73, 33 or 1 cat(s), respectively; infections with taeniid and Dipylidium cestodes were demonstrated in 39 and 17 cats, respectively. Cats were allocated randomly to one of two treatments in a ratio of 2, topical fipronil (8.3%, w/v), (S)-methoprene (10%, w/v), eprinomectin (0.4%, w/v) and praziquantel (8.3%, w/v) (BROADLINE(®), Merial; 130 cats); and 1, topical PROFENDER(®) Spot-On (Bayer; 66 cats) and treated once on Day 0. For evaluation of efficacy, two faecal samples were collected, one prior to treatment (Day -4 ± 4 days) and one at the end of the study (Day 14 ± 5 days). These were examined for fecal forms of nematode and cestode parasites. For evaluation of safety, cats were examined by a veterinarian before treatment and at the end of the study, and cat owners recorded the health status of their cats daily until the end of the study. For cats treated with Broadline(®), the efficacy was >99.9%, 100%, and 99.6% for Toxocara, hookworms, and Capillaria, respectively; and the efficacy was >99.9%, >99.9%, and 98.5%, respectively, for the cats treated with Profender(®) (p<0.001 for all nematodes and both treatments). Efficacy was 100% for both cestodes for both treatments (p<0.001). No treatment related adverse experiences were observed throughout the study. For both treatments, every cat that completed the study was given a safety score of 'excellent' for both local and systemic evaluations. The topical combination product of fipronil, (S)-methoprene, eprinomectin and praziquantel was shown to have an excellent safety profile and demonstrated high levels of efficacy when administered once as topical solution to cats infected with nematodes and cestodes under field conditions. PMID:24703070

  2. A Multicentre Randomized Controlled Trial of the Efficacy and Safety of Single-Dose Praziquantel at 40 mg/kg vs. 60 mg/kg for Treating Intestinal Schistosomiasis in the Philippines, Mauritania, Tanzania and Brazil

    PubMed Central

    Olliaro, Piero L.; Vaillant, Michel T.; Belizario, Vincente J.; Ouldabdallahi, Mohamed; Pieri, Otavio S.; Amarillo, Maria L.; Kaatano, Godfrey M.; Diaw, Mamadou; Domingues, AnaLucia C.; Favre, Tereza C.; Lapujade, Olivier; Alves, Fabiana; Chitsulo, Lester

    2011-01-01

    Background Praziquantel at 40 mg/kg in a single dose is the WHO recommended treatment for all forms of schistosomiasis, but 60 mg/kg is also deployed nationally. Methodology/Principal Findings Four trial sites in the Philippines, Mauritania, Tanzania and Brazil enrolled 856 patients using a common protocol, who were randomised to receive praziquantel 40 mg/kg (n?=?428) or 60 mg/kg (n?=?428). While the sites differed for transmission and infection intensities (highest in Tanzania and lowest in Mauritania), no bias or heterogeneity across sites was detected for the main efficacy outcomes. The primary efficacy analysis was the comparison of cure rates on Day 21 in the intent-to-treat population for the pooled data using a logistic model to calculate Odd Ratios allowing for baseline characteristics and study site. Both doses were highly effective: the Day 21 cure rates were 91.7% (86.6%–98% at individual sites) with 40 mg/kg and 92.8% (88%–97%) with 60 mg/kg. Secondary parameters were eggs reduction rates (ERR), change in intensity of infection and reinfection rates at 6 and 12 months. On Day 21 the pooled estimate of the ERR was 91% in both arms. The Hazard Ratio for reinfections was only significant in Brazil, and in favour of 60 mg/kg on the pooled estimate (40 mg/kg: 34.3%, 60 mg/kg: 23.9%, HR?=?0.78, 95%CI?=?[0.63;0.96]). Analysis of safety could not distinguish between disease- and drug-related events. 666 patients (78%) reported 1327 adverse events (AE) 4 h post-dosing. The risk of having at least one AE was higher in the 60 than in the 40 mg/kg group (83% vs. 73%, p<0.001). At 24 h post-dosing, 456 patients (54%) had 918 AEs with no difference between arms. The most frequent AE was abdominal pain at both 4 h and 24 h (40% and 24%). Conclusion A higher dose of 60 mg/kg of praziquantel offers no significant efficacy advantage over standard 40 mg/kg for treating intestinal schistosomiasis caused by either S. mansoni or S. japonicum. The results of this study support WHO recommendation and should be used to inform policy decisions in the countries. Trial Registration Controlled-Trials.com ISRCTN29273316 ClinicalTrials.gov NCT00403611 PMID:21695161

  3. Falta de investimento prejudica sector em Portugal

    E-print Network

    Instituto de Sistemas e Robotica

    Falta de investimento prejudica sector em Portugal O país tem bons profissionais e potencialidades comunidade científica, em aplicar os conhecimentos na área e Portugal "tem uma boa infra-estrutura humana e, mas em Portugal investe-se apenas nos três primeiros anos - leva muitos investigadores a desistir

  4. A Gestão Estratégica das Instituições de Ensino Superior: uma contribuição ao melhor desempenho no caso brasileiro

    Microsoft Academic Search

    Alfredo Colenci Júnior; Ana Lúcia Spigolon; Marco Anselmo de Godoi; Maria Elizete Luz Sáes

    Resumo: O crescimento no número de instituições de Ensino Superior no Brasil tem provocado inadequações, decorrentes da má gestão e do baixo comprometimento em relação à qualidade do processo educacional. O não alinhamento da educação superior com políticas de desenvolvimento e a falta de uma efetiva regulamentação institucional, no atendimento às demandas regionais, representam uma grave dispersão de esforços e

  5. PRODUÇÃO SUSTENTÁVEL EM RESERVAS EXTRATIVISTAS

    Microsoft Academic Search

    Jose Otavio Valiante; Osmar Siena

    2008-01-01

    Este trabalho discute questões relacionadas à produção sustentável em Reservas Extrativistas (RESEX). Com a finalidade de identificar temas prioritários foi aplicada a ferramenta Brainwriting 6-3-5, tendo como pano de fundo a Reserva Extrativista do Rio Ouro Preto\\/RO, com uma equipe de técnicos do IBAMA em Guajará-Mirim\\/RO e representantes da comunidade da RESEX. Em um segundo momento foi aplicado um questionário

  6. DIAGNÓSTICO ESTRATÉGICO: ANÁLISE DOS AMBIENTES INTERNO E EXTERNO DE UMA AGROINDÚSTRIA GOIANA

    Microsoft Academic Search

    Christian Drees; Eliane Moreira De Sa Souza; Odilon Jose De Oliveira Neto; Reginaldo Santana Figueiredo

    2008-01-01

    O objetivo deste estudo foi prospectar cenários para a unidade em estudo; e desenvolver um diagnóstico estratégico do processo de produção de óleos vegetais da organização em estudo. Quanto à metodologia, trata-se de uma pesquisa-ação, cujos dados foram obtidos por fontes primárias e secundárias. Para retratar a análise do ambiente interno e possibilitar acompanhamento das mudanças, pela proposta de Mintzberg,

  7. Uma Krishnaswami and International Imaginings

    ERIC Educational Resources Information Center

    Aldama, Frederick Luis

    2006-01-01

    This article presents an interview with South Asian children's book and young adult fiction writer, Uma Krishnaswami. The interviewer states that "in all her creative endeavors Uma's keen sense of detail, narrative voice, and characterization complicate and humanize portrayals of multicultural peoples worldwide." In this interview, Krishnaswami…

  8. Populações estelares em galáxias HII

    NASA Astrophysics Data System (ADS)

    Westera, P.; Cuisinier, F.; Telles, E.; Kehrig, C.

    2003-08-01

    Analisamos o conteúdo estelar de 74 galáxias HII a partir do contínuo observado nos espectros ópticos dessas galáxias, utilizando métodos de síntese de população estelar. Descobrimos que todas as galáxias para as quais encontramos soluções contêm uma população estelar velha que domina a massa estelar, e numa maioria dessas também encontramos evidência de uma população de idade intermediaria além da geração jovem que está se formando agora. Concluímos que a formação estelar dessas galáxias se realiza em surtos individuais, Esses surtos são interrompidos por longos períodos de inatividade, com os primeiros consumindo a maior parte do gás. Sugerimos, portanto, que as galáxias HII sejam galáxias anãs normais flagradas em um período de surto.

  9. OS RECENSEAMENTOS DEMOGRAFICOS : UMA FONTE DE INFORMAO SOBRE A FILIAO

    E-print Network

    Boyer, Edmond

    5 OS RECENSEAMENTOS DEMOGRAFICOS : UMA FONTE DE INFORMA��O SOBRE A FILIA��O RELIGIOSA NO BRASIL NO BRASIL O Brasil é um país de tradição estatística. Os recenseamentos são, em princípio, realizados a cada *** Geógrafa, Pontifícia Universidade Católica, PUC, Rio de Janeiro ­ Brasil. #12;PHILIPPE WANIEZ VIOLETTE

  10. A LOUCURA REAL E VISIONRIA DE DOM SEBASTIO EM MENSAGEM

    Microsoft Academic Search

    Cladismari Zambon de Moraes

    Resumo: A presenÁa de uma figura mÌtica e louca como Dom Sebastiªo na obra Mensagem, de Fernando Pessoa, mostra-se como uma forma de resistŒncia e estÌmulo ao levante nacional pretendido em uma Øpoca de des‚nimo e desesperanÁa. A loucura, vista pelo ponto de vista da Antipsiquiatria, pode ser compreendida como uma voz inaudita de resistŒncia ‡s regras opressivas da sociedade,

  11. Astronomia cultural e meio ambiente segundo uma abordagem holística

    NASA Astrophysics Data System (ADS)

    Jafelice, L. C.

    2003-08-01

    Neste trabalho ampliamos a discussão da abordagem holística para o ensino de astronomia que temos desenvolvido nos últimos anos, analisamos novos resultados e apresentamos exemplos práticos para interessados em experimentá-la. A constatação básica a orientar este enfoque é que cursos introdutórios em astronomia costumam ser excessiva e prematuramente técnicos, além de assumirem uma visão tradicional, muito estreita, do que seja educação científica, herdada da era cartesiana e positivista da ciência. Fundamentamos porque é importante que elementos de astronomia cultural ofereçam o mote e constituam o eixo norteador daqueles cursos e porque é urgente revermos a visão que temos da relação entre astronomia e meio ambiente. Um ponto central nesta abordagem é explorar formas de reativar e atualizar uma relação orgânica com o meio e excitar a consciência de nossa inevitável e profunda interdependência com ele em nível cósmico. Neste trabalho exemplificamos a possibilidade de concretização desta proposta em três diferentes situações: disciplinas de cursos de licenciatura em geografia e em física; escolas de nível fundamental; e, neste caso ainda a ser implementada, comunidades carentes. Estes casos envolvem públicos e espaços diferenciados para educação formal e não-formal. Dos casos já implementados, destacamos os resultados alcançados pelos alunos: enriquecimento cultural, aprendizagem significativa de conteúdos astronômicos tradicionais; mudanças de comportamento, incorporando contato diário com o céu; e freqüentes vivências de sentimentos empáticos que redirecionam a relação com a natureza e a consciência ecológica global. Além disto, para interessados em aplicar esta proposta, também socializamos procedimentos e cuidados para a implementação de ações alternativas consonantes com a mesma. (PPGECNM/UFRN; PRONEX/FINEP; NUPA/USP; Temáticos/FAPESP)

  12. Marvin, robô construtor para competição em robótica móvel

    Microsoft Academic Search

    André Martin Narciso; Carlos Augusto; Bentes da Silva; Jackson Paul Matsuura

    renatohsp@gmail .com Resumo: Este artigo é sobre a construção do robô autônomo Marvin o Construtor, que foi construído para participar da IV Competição IEEE Brasileira de Robô. A tarefa consiste em empilhar blocos em uma área predeterminada em um menor tempo possível, ganha a torre mais alta. O robô, construído por alunos do Instituto Tecnológico de Aeronáutica (ITA), foi construído

  13. O ensino itinerante como suporte para a inclusão de pessoas com necessidades educacionais especiais na rede pública de ensino: uma abordagem etnográfica1

    Microsoft Academic Search

    Márcia Denise Pletsch; Rosana Glat

    O presente artigo tem como objetivo discutir o papel e atribuições cotidianas do professor itinerante — professor especialista em Educação Especial que dá suporte a escolas que têm alunos com necessidades educacionais especiais incluídos em classes regulares. O texto está fundamentado nos dados obtidos em uma pesquisa realizada na Rede Pública de Ensino da Cidade do Rio de Janeiro, Brasil.

  14. Halema'uma'u vent

    USGS Multimedia Gallery

    Several collapses early this morning exposed more of the lava pond deep within the Halema`uma`u vent cavity. For the last several days, glowing and spattering holes (top image) have been active on the floor of the vent cavity, at a depth of about 200 m below the vent rim. At 3:06 am, a parti...

  15. Uma Estratégia de Suporte à Educação em IHC

    Microsoft Academic Search

    Ecivaldo de Souza Matos

    This paper describes a research about a strategy of education in Human-Computer Interaction (HCI). This work has used workflows, e- learning and aspects of knowledge management. Educational methodologies based in present dynamics of work are very important. Those methodologies must foment the production and absorption of knowledge efficiently and with the shortest disruption of the development process. Its mainly is

  16. DESENVOLVIMENTO DE UMA PLATAFORMA DE FORÇA EM PEDAL DE CICLISMO

    Microsoft Academic Search

    Carlos Dreyer Neto; Guilherme Schmidt; Cláudia Tarragô Candotti

    2001-01-01

    A strain gauges instrumented clipless force-plataform pedal similar to those used in competition by cyclists and triathletes was designed and constructed. The system is capable of measuring the two forces components along the cycle stride. The geometry of the pedal was comprised of four beams in balance allowed the use of two full Wheatstone Bridges, one for normal forces and

  17. Ensino Superior de excelncia altura em que o Ensino Superior portugus granjeia de significativa notoriedade

    E-print Network

    Instituto de Sistemas e Robotica

    Ensino Superior de excelência Numa altura em que o Ensino Superior português granjeia de.° melhor do mundo em 20 12, tendo subido uma posição em relação ao ranking do ano anterior. Portugal melhora em todos os indicadores avaliados pela lista elaborada pela rede internacional Universitas 2 1

  18. Comparative Speed of Kill, Repellent (anti-feeding) and Acaricidal Efficacy of an Imidacloprid/Flumethrin Collar (Seresto(®)) and a Fipronil/(S)-Methoprene/Eprinomectin/Praziquantel Spot-on (Broadline (®)) against Ixodes ricinus (Linné, 1758) on Cats.

    PubMed

    Fourie, Josephus J; Horak, Ivan G; de Vos, Christa; Deuster, Katrin; Schunack, Bettina

    2015-08-01

    Speed of kill, repellent (anti-feeding) and acaricidal efficacy of an imidacloprid 10 % (w/w) /flumethrin 4.5 % (w/w) collar (Seresto(®), Bayer) and a spot-on formulation of fipronil 8.3 % (w/v) /(S)-methoprene 10 % (w/v) /eprinomectin 0.4 % (w/v) /praziquantel 8.3 % (w/v) (Broadline(®), Merial) against artificiallyinduced infestations with Ixodes ricinus on cats, were assessed in a parallel group design, randomised, controlled study. Twenty-four cats were included and randomly allocated to treatment groups or a non-treated control group. Starting on Day (D) 7 after treatment until D28, cats were each infested with 50 I. ricinus at weekly intervals. Ticks were counted in situ on the cats at 6, 12 and 24 h and upon removal 48 h after each infestation. Based on arithmetic means, Seresto(®) proved to be 100 % effective against adult I. ricinus at all assessment times (6, 12, 24 and 48 h after infestation) throughout the month-long study. Broadline(®) was 0 % to 16.7 % effective at 6 h, 26.8 % to 50.0 % effective at 12 h, while at 24 h after infestation efficacy peaked at 81.5 % on D15 declining to 31.5 % on D29. Based on the 48 h tick counts, the efficacy of Broadline(®) peaked at 100 % on D16 after treatment and decreased to 83.2 % by D30. The Seresto(®) collar provided significantly faster speed of kill and better persistent acaricidal effectiveness against Ixodes ricinus on cats compared to Broadline(®) spot-on. The additional repellent (anti-feeding) effect of Seresto(®) prevents parasites from taking a blood meal and thereby reduces the risk of vector-borne disease pathogen transmission. PMID:26152412

  19. Field evaluation of the efficacy and the safety of a combination of oxantel/pyrantel/praziquantel in the treatment of naturally acquired gastrointestinal nematode and/or cestode infestations in dogs in Europe.

    PubMed

    Grandemange, E; Claerebout, E; Genchi, C; Franc, M

    2007-04-10

    In five multicentre field trials, the efficacy and safety of a combination of oxantel/pyrantel/praziquantel (Dolpac), Vetoquinol SA) in the treatment of naturally acquired gastrointestinal nematode and/or cestode infestation in dogs was evaluated in northern and southern Europe. Forty-eight investigators from France, Belgium, Germany, Italy and Spain enrolled 329 dogs to be treated with the tested combination; 235 of these dogs complied with the inclusion criteria of the protocol and had a tested helminth identified on Day 0. A pooled analysis was performed on each of the following helminth species: Toxocara canis, Ancylostoma caninum, Toxascaris leonina, Trichuris vulpis, Uncinaria stenocephala, Taenia spp. and Dipylidium caninum, which were isolated on Day 0. The main efficacy criterion was the egg per gram (epg) percent reduction of the nematodes and the absence of proglottids and or eggs for the cestodes. After treatment, dogs were examined on Day 7, Day 14 and Day 21. The efficacy of the combination against Toxocara canis was 99.1%, 98.8% and 98.9% on Day 7, Day 14 and Day 21, respectively. At the same occasions the efficacy was, respectively, 99.2%, 99.2% and 99.3% against Ancylostoma caninum, 97.3%, 97.2% and 98.4% against Trichuris vulpis, 98.4%, 98.8% and 98.8% against Uncinaria stenocephala, 98.9%, 99.5% and 99.9% against Toxascaris leonina, 97.1%, 100% and 100% against Dipylidium caninum and 100% against Taenia spp. PMID:17184919

  20. Uma análise do fenômeno “alternância de línguas” na fala de bilíngues intermodais (Libras e Português)

    PubMed Central

    de Sousa, Aline Nunes; de Quadros, Ronice Müller

    2013-01-01

    Um interessante fenômeno lingüístico presente nas interações das pessoas bilíngues é a alternância de línguas. Neste trabalho, estamos investigando a alternância entre a língua portuguesa oral e a língua de sinais brasileira – Libras, numa mesma cadeia enunciativa, com o objetivo de identificar e analisar o uso dessa alternância na fala de uma criança e de um adulto (ambos ouvintes, filhos de pais surdos), interagindo em uma situação de bilinguismo intermodal, com interlocutores surdos e ouvintes. A alternância de línguas, nesse caso, ocorre quando se para de falar em português e se alterna para sinalizar. O presente trabalho se caracteriza como um estudo inicial, com análise qualitativa de dados. Fazem parte do nosso corpus nove sessões de interações em Libras e em português oral, gravadas em vídeo, que fazem parte do Projeto Desenvolvimento Bilíngue Bimodal da UFSC. Os dados revelam que as características da alternância de línguas pelo adulto e pela criança parecem ter semelhanças e diferenças. O sujeito adulto parece ter feito um uso da alternância mais preocupado com o curso da interação. A criança, por sua vez, não parece tê-la usado com propósitos pragmáticos específicos. Quanto à extensão das alternâncias, pode-se perceber que tanto a criança quanto o adulto utilizaram enunciados maiores do que uma única palavra isolada. O papel dos interlocutores parece ter sido decisivo nas interações aqui investigadas – especialmente nas do adulto, já que a criança ainda está em processo de tomada de consciência do papel do interlocutor na interação. PMID:24379831

  1. Lepo: Sistema de Apoio à Decisão Médica em Oftalmologia Baseado no Sistema Lepidus

    Microsoft Academic Search

    Antonio Carlos; Roque da Silva; Juliana Mantovani Bottós; Ivan Torres Pisa; Andréia Cristina Galina

    Resumo - O projeto Lepo visa desenvolver uma versão do sistema Lepidus especializada em oftalmologia. Esse sistema baseia-se em uma codificação original através de funções senoidais amortecidas de sinais e sin- tomas médicos para descrever doenças. Oferece consulta remota via Internet para auxiliar médicos no diagnós- tico de seus pacientes como segunda opinião. Para adaptar o sistema Lepidus para descritores

  2. Descoberta e Monitoramento de Recursos em Redes de Computadores usando Agentes Móveis

    Microsoft Academic Search

    Inácio Dutra; Joaquim Celestino

    Resumo. Com a expansão e proliferação de novas tecnologias de rede e a demanda d e novos serviços vem tornando cada vez mais difícil administrar redes em larga escala sem um sistema d e gerenciamento inteligente, automatizado. Descobrir e manter um mapeamento da topologia de uma rede são essenciais para se ter uma administração efetiva. Neste artigo apresentamos uma a

  3. GLOBAL WATER WATCH, UMA REDE MUNDIAL PARA MONITORAMENTO DE ÁGUA COM PARTICIPAÇÃO COMUNITÁRIA

    Microsoft Academic Search

    BRYAN L. DUNCAN; WILLIAM G. DEUTSCH; CARLOS EDUARDO SISTE

    Global Water Watch (GWW) é uma rede para monitoramento da água, baseada na participação da comunidade, e coordenado pela universidade de Auburn, Alabama, Estados Unidos da América. Os principais objetivos do GWW são fornecer oficinas de treinamento, assistência técnica, e gerência dos dados para os grupos dos cidadãos que têm interesse em avaliação e proteção de bacias hidricas e fontes

  4. AVALIAÇÃO BIOMECÂNICA DOS TRABALHADORES EM MARCENARIAS NO DISTRITO

    Microsoft Academic Search

    Nilton Cesar Fiedler; Natália S. Menezes; Nuno C. Azevedo; José Reinaldo Moreira da Silva

    2003-01-01

    A pesquisa foi desenvolvida com base em dados coletados com funcionários de marcenarias no Distrito Federal com o objetivo de fazer uma avaliação biomecânica do trabalhador nas mais diversas máquinas. A avaliação foi feita com a filmagem dos trabalhadores em perfil, avaliação das forças envolvidas e posterior congelamento das imagens e medição dos ângulos das articulações para análise no software

  5. Psiquiatria baseada em evidências Evidence-based psychiatry

    Microsoft Academic Search

    Maurício S de Lima; Bernardo GO Soaresb e; Josué Bacaltchuk

    Em psiquiatria, observa-se grande variabilidade de práticas clínicas, muitas vezes desnecessária. Essas varia- ções podem estar relacionadas à ausência de evidência científica confiável ou ao desconhecimento das evidên- cias de boa qualidade disponíveis. A medicina baseada em evidências (MBE) é uma combinação de estratégias que busca assegurar que o cuidado individual do paciente seja baseado na melhor informação disponível, a

  6. Agregao em solventes no aquosos Anfifilicidade vs. Liofobicidade solventes de alta energia

    E-print Network

    Loh, Watson

    Agregação em solventes não aquosos Anfifilicidade vs. Liofobicidade ­ solventes de alta energia coesiva Parâmetro de Gordon = / (Vm)1/3 (valores entre 2,7 e 1,3 J m-3) Não há evidências de agregação em) ­ micelas unimoleculares Micela/Agregado ­ micela significa agregados estáveis/constantes em uma faixa de

  7. Aquilo que no tem sido dito no debate sobre a "Cincia em crise"

    E-print Network

    Instituto de Sistemas e Robotica

    Aquilo que não tem sido dito no debate sobre a "Ciência em crise" José Manuel Fernandes Extremo últimos dias a experiência de mais uma "zona de J desastre". Desta vez, garante- se, o que está em causa é o futuro da Ciência em Portugal. Como é típico nestas situações, o "consenso" que rapidamente se

  8. Recursos Estratégicos em Propriedades Rurais Familiares

    Microsoft Academic Search

    Marcelo Fernandes Pacheco Dias; Eugenio Avila Pedrozo

    2008-01-01

    A agricultura familiar tem papel importante nos agronegócios. A manutenção desses agricultores é uma das preocupações prioritárias dos governos. Também é amplamente conhecido o fato que o desempenho das propriedades familiares varia significativamente. Esse artigo busca contribuir para a explicação do porquê dessa variação de desempenho, através da Teoria Baseado em Recursos (RBV). Nesse sentido, foi desenvolvido um estudo exploratório

  9. PROBLEMA, TEORIA E OBSERVAÇÃO EM CIÊNCIA : PARA UMA REORIENTAÇÃO EPISTEMOLÓGICA DA EDUCAÇÃO EM CIÊNCIA

    Microsoft Academic Search

    Daniel Gil-Pérez

    2002-01-01

    Science teachers play an important role in forming the image of science that is held by their pupils. However, recent research suggests that quite often science teachers conceptions of the nature of scientific knowled- ge are marked by empiricist\\/inductivist epistemologies. Thus, the present paper aims to help science teachers to have a better understanding the epistemology of science aspects which

  10. Curso de Calculo de Uma Variavel

    E-print Network

    Cabral, Marco

    Curso de C´alculo de Uma Vari´avel Terceira Edic¸ ~ao d dx d dx d dx d dx dxdx dx dx sen x cos x dx d dx dx d dx dx Marco Cabral #12;ii #12;Curso de Cálculo de Uma Variável Terceira Edição 1 de. Curso de Cálculo de Uma Variável / Marco Cabral - Rio de Janeiro: Instituto de Matemática, 2010. 1

  11. GEOPROCESSAMENTO APLICADO A ECOLOGIA DE PAISAGEM: UMA ANÁLISE DA DINÂMICA ESPACIAL DA ILHA DO PAPAGAIO – PA, AMAZÔNIA-BRASIL

    Microsoft Academic Search

    Joyse Tatiane Souza dos Santos; Heriberto Wagner Amanajás Pena

    2011-01-01

    O geoprocessamento é uma importante ferramenta para se compreender a estrutura e a dinâmica das paisagens em diversas escalas temporais e espaciais, quando aplicado à ecologia de paisagem traz elementos tanto para o estudo das interações do homem com o meio ambiente, quanto para compreender os processos ecológicos. Dessa forma objetiva-se com este artigo, levantar as situações ambientais associadas à

  12. Redução na tributação indireta de alimentos no Brasil: estimativas preliminares baseadas em um banco de dados em construção para o ano de 2004

    Microsoft Academic Search

    Carliton Vieira dos Santos; Joaquim Bento de Souza Ferreira Filho

    2008-01-01

    Este artigo analisa os efeitos potenciais de uma redução dos tributos indiretos sobre os principais produtos alimentícios consumidos pelas famílias, em nível nacional e regional. A análise é implementada com o uso de um modelo aplicado de equilíbrio geral inter-regional calibrado para o ano de 2004. Os resultados da simulação mostram que uma política como esta conduz a um aumento

  13. Sistemas Distribuidos e Redes de Sensores Comunicac~ao em Grupo

    E-print Network

    Rodriguez, Noemi

    Sistemas Distribu´idos e Redes de Sensores Comunica¸c~ao em Grupo abril de 2013 Comunica¸c~ao em grupo #12;Grupos em Aplica¸c~oes Distribu´idas exemplos: replica¸c~ao de servi¸cos clientes com estado compartilhado computa¸c~ao cient´ifica ... Primitiva de comunica¸c~ao em grupo um processo envia uma mensagem

  14. REALIZAO DE UM SERVIO DE GRUPOS LIGEIROS PARA A PLATAFORMA DE COMUNICAO EM GRUPO Hugo Miranda, Francisco Costa e Lus Rodrigues

    E-print Network

    Rodrigues, Luís E.T.

    REALIZAÇÃO DE UM SERVIÇO DE GRUPOS LIGEIROS PARA A PLATAFORMA DE COMUNICAÇÃO EM GRUPO ENSEMBLE Hugo a concretização de uma versão eficiente deste serviço, designada por Grupos Ligeiros, na plataforma Ensemble] é uma plataforma de comunicação fiável em grupo, desenvolvida na Universidade de Cornell, usando

  15. DIAGNÓSTICO DA AMBIÊNCIA ORGANIZACIONAL DA COMUNIDADE DE PRODUTORES DE PIMENTA LONGA (PIPER HISPIDINERVUM) UNIÃO DA LINHA SEIS DO PROJETO DE COLONIZAÇÃO HUMAITÁ EM PORTO ACRE – AC

    Microsoft Academic Search

    Solange Maria Chalub Bandeira Teixeira; Lucas Araujo Carvalho

    2008-01-01

    Este trabalho apresenta o resultado parcial de uma pesquisa maior sobre a avaliação ambiental e sócio-econômica da produção de pimenta longa (Piper hispidinervum) de uma comunidade de produtores de um projeto de colonização do INCRA. Trata-se da sistematização do que foi levantado em campo, através de pesquisa realizada com 10 (dez) produtores rurais, pertencentes a uma associação de produtores do

  16. O CONSUMO CONSCIENTE NA AGRICULTURA, O CASO DA DESTINAÇÃO FINAL DAS EMBALAGENS DE AGROTÓXICOS EM PIRACICABA (SP)

    Microsoft Academic Search

    Francine Meca Vignotto; Eduardo Eugenio Spers

    2008-01-01

    O consumidor consciente tem um papel importante na sociedade ao adotar práticas em suas escolhas cotidianas que privilegiam aspectos como sustentabilidade e responsabilidade social. A atividade agrícola é conhecida por seu impacto no meio ambiente e a decisão de minimizá-lo recai em geral sobre um indivíduo, o produtor rural. Com base em uma escala de consciência sobre tratos culturais agrícolas

  17. F589 -QUINTA LISTA DE EXERCICIOS 1. Mostre, para um atomo de Thompson, que um eletron que esta em movimento em

    E-print Network

    de Aguiar, Marcus A. M.

    ´a em movimento em uma ´orbita circular est´avel gira com a mesma frequ^encia com que ele oscilaria em. Mostre que a frequ^encia de rota¸c~ao de um el´etron em um ´atomo no modelo de hidrog^enio de Bohr ´e´etron de um ´atomo de hidrog^enio em um estado com n=8? 1 #12;9. Mostre que quando a energia cin´etica de

  18. Thermal Image of Halema'uma'u

    USGS Multimedia Gallery

    This image was collected from a thermal camera at the Halema`uma`u Overlook, and shows the current activity at the summit. The active lava pond, about 40 m across, is situated deep within the vent cavity, at a depth of about 200 m. The lava surface consists of slowly migrating crustal plates...

  19. Halema'uma'u Maintains Basic Geometry

    USGS Multimedia Gallery

    The lava lake at Halema'uma'u has maintained the same basic geometry since February of this year. This thermal image was taken during a helicopter overflight, and shows the lava surface deep within the vent cavity. The lava surface is kidney-shaped and approximately 60 x 90 meters in size, and situa...

  20. A saúde mental do trabalhador em saúde mental: um estudo com trabalhadores de um hospital psiquiátrico

    Microsoft Academic Search

    Tatiana Ramminger

    1 Resumo: O presente estudo propõe uma reflexão sobre a saúde mental do trabalhador em saúde mental, a partir do levantamento das características sócio-demográficas e funcionais dos trabalhadores atendidos pelo Serviço de Engenharia, Segurança e Medicina do Trabalho - (Sesmt) de um hospital psiquiátrico, entre março e agosto de 2001, cujo diagnóstico se reporta a transtornos mentais. Funda- menta-se em

  1. Estudo anatômico do crescimento do fruto em Acca sellowiana Berg

    Microsoft Academic Search

    Karin Esemann-Quadros; Ana Paula Mota; Gilberto Barbante Kerbauy; Miguel Pedro Guerra; Jean Pierre Henri Joseph Ducroquet; Rosete Pescador

    2008-01-01

    RESUMO - A Acca sellowiana Berg. (Myrtaceae) é uma frutífera nativa dos planaltos meridionais do Sul do Brasil e que se encontra em processo de domesticação. Seus frutos são doce-acidulados e podem ser consumidos in natura ou empregados para a produção de sucos e doces. Assim, informações sobre o desenvolvimento, morfologia e anatomia de seus frutos são de grande interesse

  2. UM PROJETO ALTERNATIVO PARA INICIAÇÃO EM TECNOLOGIAS DIFITAIS NA FORMAÇÃO INICIAL DE PROFESSORES DE CIÊNCIAS E BIOLOGIA

    Microsoft Academic Search

    Simão Marinho

    Uma discussão sobre a formação de professores que sejam capazes de incorporar as tecnologias digitais na educação como recurso no processo de ensino -aprendizagem nas escolas da educação básica no Brasil passa necessariamente por um questionament o da prática atual das nossas licenciaturas em plena Era da Informação... De uma maneira geral, nas licenciaturas brasileiras ainda não se usam os

  3. PAISAGEM E HINOS NACIONAIS: UMA NARRATIVA DA NAÇÃO 1

    Microsoft Academic Search

    Tiago José Berg

    RESUMO O hino nacional, junto com a bandeira e o brasão de armas são os três símbolos através dos quais um país independente proclama sua identidade e soberania; eles são signos que carregam uma afinidade especial para as nações que representam, distinguindo-as umas das outras, e reafirmando suas fronteiras de identidade. Eles projetam valores culturais associados a uma identidade política

  4. A Concepção de Família de uma Mulher-Mãe de Vítimas de Incesto The Concept of Family from a Woman-Mother Victim of Incest

    Microsoft Academic Search

    Martha Giudice Narvaz; Sílvia Helena Koller

    Resumo O objetivo deste estudo foi o de investigar os discursos patriarcais inscritos nas concepões de família que têm sido mantidos ainda na atualidade. A participante do estudo foi uma mulher-mãe, vítima de violência na infância e na vida adulta, cujas filhas foram vítimas de incesto. O delineamento utilizado foi o estudo de caso, baseado em entrevistas semidirigidas. Os dados

  5. Telescópio de patrulhamento solar em 12 GHz

    NASA Astrophysics Data System (ADS)

    Utsumi, F.; Costa, J. E. R.

    2003-08-01

    O telescópio de patrulhamento solar é um instrumento dedicado à observação de explosões solares com início de suas operações em janeiro de 2002, trabalhando próximo ao pico de emissão do espectro girossincrotrônico (12 GHz). Trata-se de um arranjo de três antenas concebido para a detecção de explosões e determinação em tempo real da localização da região emissora. Porém, desde sua implementação em uma montagem equatorial movimentada por um sistema de rotação constante (15 graus/hora) o rastreio apresentou pequenas variações de velocidade e folgas nas caixas de engrenagens. Assim, tornou-se necessária a construção de um sistema de correção automática do apontamento que era de fundamental importância para os objetivos do projeto. No segundo semestre de 2002 empreendemos uma série de tarefas com o objetivo de automatizar completamente o rastreio, a calibração, a aquisição de dados, controle de ganhos, offsets e transferência dos dados pela internet através de um projeto custeado pela FAPESP. O rastreio automático é realizado através de um inversor que controla a freqüência da rede de alimentação do motor de rastreio podendo fazer micro-correções na direção leste-oeste conforme os radiômetros desta direção detectem uma variação relativa do sinal. Foi adicionado também um motor na direção da declinação para correção automática da variação da direção norte-sul. Após a implementação deste sistema a precisão do rastreio melhorou para um desvio máximo de 30 segundos de arco, o que está muito bom para este projeto. O Telescópio se encontra em funcionamento automático desde março de 2003 e já conta com várias explosões observadas após a conclusão desta fase de automação. Estamos apresentando as explosões mais intensas do período e com as suas respectivas posições no disco solar.

  6. QUANDO A HISTÓRIA INVADE A CENA: O CASO VLADIMIR HERZOG (RE)SIGNIFICADO POR FERNANDO PEIXOTO EM \\

    Microsoft Academic Search

    Ludmila Sá de Freitas

    Primeiramente, deve-se ressaltar que a proposta desta pesquisa (que se encontra em estágio inicial e que, portanto, muitos questionamentos são apenas apontados neste texto) é uma reflexão sobre a encenação do espetáculo teatral Ponto de Partida de Gianfrancesco Guarnieri, em 1976, no Teatro TAIB (SP), numa produção de Othon Bastos Produções Artísticas e Documenta Produções Artísticas. Neste sentido, tais análises

  7. Astronomia para/com crianças carentes em Limeira

    NASA Astrophysics Data System (ADS)

    Bretones, P. S.; Oliveira, V. C.

    2003-08-01

    Em 2001, o Instituto Superior de Ciências Aplicadas (ISCA Faculdades de Limeira) iniciou um projeto pelo qual o Observatório do Morro Azul empreendeu uma parceria com o Centro de Promoção Social Municipal (CEPROSOM), instituição mantida pela Prefeitura Municipal de Limeira para atender crianças e adolescentes carentes. O CEPROSOM contava com dois projetos: Projeto Centro de Convivência Infantil (CCI) e Programa Criança e Adolescente (PCA), que atendiam crianças e adolescentes em Centros Comunitários de diversas áreas da cidade. Esses projetos têm como prioridades estabelecer atividades prazerosas para as crianças no sentido de retirá-las das ruas. Assim sendo, as crianças passaram a ter mais um tipo de atividade - as visitas ao observatório. Este painel descreve as várias fases do projeto, que envolveu: reuniões de planejamento, curso de Astronomia para as orientadoras dos CCIs e PCAs, atividades relacionadas a visitas das crianças ao Observatório, proposta de construção de gnômons e relógios de Sol nos diversos Centros Comunitários de Limeira e divulgação do projeto na imprensa. O painel inclui discussões sobre a aprendizagem de crianças carentes, relatos que mostram a postura das orientadoras sobre a pertinência do ensino de Astronomia, relatos do monitor que fez o atendimento no Observatório e o que o número de crianças atendidas representou para as atividades da instituição desde o início de suas atividades e, em particular, em 2001. Os resultados são baseados na análise de relatos das orientadoras e do monitor do Observatório, registros de visitas e matérias da imprensa local. Conclui com uma avaliação do que tal projeto representou para as Instituições participantes. Para o Observatório, em particular, foi feita uma análise com relação às outras modalidades de atendimentos que envolvem alunos de escolas e público em geral. Também é abordada a questão do compromisso social do Observatório na educação do público em questão.

  8. SU UMa stars: Rebrightenings after superoutburst

    NASA Astrophysics Data System (ADS)

    Meyer, Friedrich; Meyer-Hofmeister, Emmi

    2015-06-01

    SU UMa stars after their long superoutbursts often show single or multiple rebrightenings. We show how this phenomenon can be understood as repeated reflections of transition waves which mediate changes between the hot and the cool state of the accretion disk and travel back and forth in the outer disk region, leaving an inner part permanently hot. This points to a temporarily increased viscosity, possibly related to the formation of large-scale and longer persisting magnetic fields by the dynamo operation during the long superoutburst. The "mini-rebrightenings" in the early post-outburst light curve of V585 Lyr discovered by Kato and Osaki (2013, PASJ, 65, 97) in Kepler observations seem to be understandable as a small limit cycle of low-luminosity changes originating from a "wiggle" feature in the thermal equilibrium curve of the cool, optically thick disk.

  9. em campanha pela qualidade

    E-print Network

    Instituto de Sistemas e Robotica

    Estudantes em campanha pela qualidade #12;Alunos unidos pela educação Ensino. No dia em que se ensino superior. Promulgado pela Assembleia da República em 1987, o Dia Nacional do Estudante comemora, aquando da crise académica vivida em Portugal. Agora, as associações académicas aproveitam o dia para

  10. Novo mestrado em Engenharia

    E-print Network

    Instituto de Sistemas e Robotica

    LISBOA Novo mestrado em Engenharia Petrolífera > A secretária de Estado da Ciência, Leonor Parreira, inaugu- ra hoje, em Lisboa, um novo mes- trado em Engenharia do Petróleo patrocinado pela Galp e Coimbra, a Universidade de Aveiro e a Universidade do Minho. O mestrado, em que serão abor- dadas áreas

  11. E-foto: Módulo de retificação de imagens em uma estação fotogramétrica digital

    Microsoft Academic Search

    Orlando Bernardo Filho

    This paper shows the rectification module of a photogrammetric digital workstation. Such module is part of the project e-foto. Palavras-chave: digital photogrammetry, free software, fotogrametria digital, software livre. 1. Introdução Entende-se por fotogrametria o conjunto de técnicas e rotinas de processamento de imagens fotográficas, visando a reconstrução do espaço tridimensional (espaço-objeto) através de imagens bidimensionais (espaço-imagem) -- Figura 1. A

  12. Uma possível interpretação da referência musical em De Umbris de Oiliam Lanna

    Microsoft Academic Search

    Cecília Nazaré de Lima

    The present study is an inquiry, based on the semiotic theory of Charles Sanders Peirce (1839-1914), about the possible meanings that can be extracted from the piece De Umbris, for two bassoons and piano, composed in 1992 by Oiliam Lanna. The horizon of this science is very broad, touching different areas of human knowledge (psychoanalysis, literature, music, etc.). The musical

  13. Pré-requisitos para implementação do sistema APPCC em uma linha de alface minimamente processada

    Microsoft Academic Search

    Adriano Gomes da Cruz; Sérgio Agostinho Cenci; Maria Cristina Antun Maia

    2006-01-01

    SUMMARY REQUIREMENTS FOR HACCP SYSTEM IMPLEMENTATION IN A MINIMALLY PROCESSED PLANT. Good Manufacturing Practices (GMP) and Sanitation Standard Procedures Operation (SSOP) are Pre-requisite Programs (PPRs) for the HACCP system implementation, being the initial step at the adoption of an Assurance Quality System in the Food Industry. A Brazilian produce line was evaluated according to PPRs compliance and microbiological analysis of

  14. Controle integrado do vetor da filariose com participação comunitária, em uma área urbana do Recife, Brasil

    Microsoft Academic Search

    Lêda Regis; André Freire Furtado; Cláudia M. Fontes de Oliveira; Cleidilene Barbosa Bezerra; Leny Rodrigues F. da Silva; Jandira Araújo; Amélia Maciel; Maria Helena Silva-Filha; Sinara B. Silva

    1996-01-01

    A pilot study for the control of Bancroftian filariasis transmission was developed in two areas of Recife, Brazil, where microfilaraemic prevalence was 10% in 1991. Mass treatment with diethylcarbamazine (DEC) using low and spaced doses was employed in both areas. In one such instance, DEC therapy was associated with vector control using physical measures and pe- riodic treatment of Culex

  15. AMBIENTE DE EXPERIMENTAÇÃO EM MANIPULAÇÃO ROBÓTICA USANDO UMA ESTAÇÃO ROBÓTICA EDUCACIONAL E PROGRAMAÇÃO MATLAB

    Microsoft Academic Search

    Humberto A. Guimarães; Frederico F. Elsner; V. H. Casanova Alcalde

    This article describes a locally developed robotic station for experiences in object manipulation. The station was implemented around the mechanical structure of the Rhino XR4 robot, having developed a multi-axis controller and a programming interface. Due to the facilities in mathematical processing and visual representation the Matlab computational environment was now chosen. A Matlab toolbox (Rhinobox) was de- veloped what

  16. Curso de Licenciatura em Matemática a Distância Uma Síntese do Projeto Pedagógico

    Microsoft Academic Search

    João Artur de Souza; Elton Luiz Vergara Nunes; Gertrudes Aparecida Dandolini; Luiz Alberto Brettas

    The increasing offer of e-learning courses in Brasil at graduate level in public institution and several undergraduate courses in private institutions, took the Ministry of Education of Brazil to establish rules to register institutions offering e- learning courses with recognized diploma. This accreditation it is only given to the Institution, when based on a evaluation of the actual offer of

  17. JOGO DE LUZES: SOMBRAS E CORES DE UMA PESQUISA EM EDUCAÇÃO AMBIENTAL 1

    Microsoft Academic Search

    Michèle Sato; Jacques Zanidê Gauthier

    Considering the four basic components of distance education - specialists, students, technological mediators and pedagogical mediators, this text aims to promote an epistemological and methodological debate in environmental education research, through sociopoetics and phenomenological dimensions. Setting sights on limits and potential of social theories, considers three major struggles on environmental education and discusses some ways to rise above the difficulties.

  18. Estudo da Freqüência da Emissão de Vórtices em uma Harpa Eólica

    Microsoft Academic Search

    Lucas Emanuel Soeira; Edson Del Rio Vieira

    2004-01-01

    Quando um escoamento contorna um corpo não aerodinâmico, sob determinadas circunstâncias, ocorre o fenômeno de emissão de vórtices. A freqüência de emissão dos turbilhões depende da geometria do corpo, do ângulo de incidência, das propriedades do meio fluido e da velocidade do escoamento. Freqüentemente, o desprendimento cíclico dos vórtices provocam forças de excitação fazendo o corpo vibrar. Esse fenômeno pode

  19. Teoria de Resposta ao Item na análise de uma prova de estatística em universitários

    Microsoft Academic Search

    Claudette Maria Medeiros Vendramini; Anelise Silva Dias

    2005-01-01

    This study aimed to use the Item Response Theory to analyze the 15 multiple-choice questions of a statistics test presented in the statistics graphics or tables form. The 414 university students were selected by convenience from two private universities, predominantly psychology students (91.5%). The university students were 80% female and with 16-53 years old, mean 24.4 and standard deviation 7.4.

  20. Programa Embu Enxergando Melhor: uma proposta de atenção integral à saúde ocular em pré-escolares

    Microsoft Academic Search

    Maria Cecília S. Lapa; Adriana Mavalli de Freitas; Glaura César Pedroso; Meiry Akiko Furusato; Renato Nabas Ventura

    2008-01-01

    Objective: Early detection and prompt treatment of ocu- lar disorders in children are important to avoid lifelong visual impairment. This study aimed to describe a comprehensive eye health care program for preschool children. Methods: A descriptive cross-sectional study was car- ried out focusing eye health conditions of 23,374 children, between five and seven years old, of the public preschool system

  1. RESOLUC ~AO DO TESTE DE AMII DE 7 DE MAIO DE 2005 1. Calcule uma primitiva das seguintes func~oes

    E-print Network

    Granja, Gustavo

    RESOLUC¸ ~AO DO TESTE DE AMII DE 7 DE MAIO DE 2005 1. Calcule uma primitiva das seguintes fun¸c~oes x 3 + 2x2 , x 2 - x2 , sin(log x) 5x , x arctg x. Desenvolva a primeira fun¸c~ao em s´erie de pot desenvolvimento da primeira fun¸c~ao em s´erie de pot^encias de x ´e o seguinte: x 3 + 2x2 = x 3 1 1 + 2 3 x2 = x

  2. Leica EM UC7 Leica EM FC7

    E-print Network

    Chapman, Michael S.

    Leica EM UC7 Leica EM FC7 High Quality Ultramicrotome for Precise Room Temperature and Cryo its latest specimen preparation technology: the Leica EM UC7 ultramicrotome and the Leica EM FC7 cryo chamber attachment. #12;3 Leica EM UC7 The Leica EM UC7 prepares excellent quality semi- and ultra

  3. Brookhaven EM Completion Project Environmental

    E-print Network

    Homes, Christopher C.

    Brookhaven EM Completion Project Office of Environmental Management 1 American Recovery Site Office Brookhaven National Laboratory Community Advisory Council April 15, 2009 #12;Brookhaven EM Environmental Management (EM) Funding and Goals Brookhaven EM ARRA Projects Description of ARRA Projects #12

  4. Ensino de gravitação clássica no nível médio: uma proposta de abordagem e resultados preliminares

    NASA Astrophysics Data System (ADS)

    Medeiros, G. C. M.; Jafelice, L. C.

    2003-08-01

    O ensino de gravitação clássica é comumente realizado de maneira formal e descontextualizado da experiência com a força-peso e da história do tema. Fustigados por anos de experiência de ensino no assunto, nem sempre com bons resultados, propomos uma abordagem ancorada nos eixos: a) contextualização histórica; e b) reconhecimento do peso como a força de atração gravitacional. O primeiro eixo integra o tema no desenvolvimento cultural do ser humano, praticando a interdisciplinaridade. O segundo eixo embasa construtivamente a abordagem, levando o aluno a realizar experiências e a vivenciar o reconhecimento de uma força universal. A abordagem foi construída através das etapas: 1) análise crítica do tema em livros didáticos; 2) elaboração de um curso para professores das várias disciplinas do ensino médio, identificando conexões para a prática da interdisciplinaridade; 3) elaboração de material didático; e 4) avaliação da eficácia da abordagem. No trabalho discutimos em detalhe as quatro etapas. Como resultados, adiantamos que: tabulamos a abordagem de gravitação nos livros didáticos, ainda muito tradicional e carecedora de atividades criativas que poderiam melhor explorar esse assunto; mapeamos, junto aos professores, padrões de conceitos espontâneos e erros associados ao tema; e, no curso, adaptamos e testamos a eficiência de materiais instrucionais existentes e criamos outros novos (e.g., para trabalhar excentricidades das órbitas planetárias), além disto elaboramos roteiros e figuras para tratamentos qualitativo e quantitativo da lei da gravitação universal. As avaliações feitas pelos professores foram muito animadoras. O espaço da presente reunião será aproveitado para socializar a proposta e os resultados obtidos e para submeter o projeto à análise crítica. (PPGECNM/UFRN; PRONEX/FINEP; NUPA/USP; Temáticos/FAPESP)

  5. UNIVERSIDADE FEDERAL DO PARAN PROGRAMA DE PS-GRADUAO EM DIREITO

    E-print Network

    Paraná, Universidade Federal do

    ECONÔMICA DA EFICIENCIA PEDRO VITOR BOTAN CÍCERI POSSIBILIDADE DE INCENTIVOS FISCAIS AO TRANSPORTE PÚBLICO: UMA FERRAMENTA DE GESTÃO PÚBLICA DANIELA DIAS ROBALO AS AVALIAÇÕES DOS SERVIDORES TÉCNICO CURITIBA JANINE ANDREIV RODRIGUES A LEI 12.305/2010 E A COLETA SELETIVA REALIZADA POR PREFEITURAS EM

  6. Deteco Distribuda de Violao de Integridade em Sistemas com Contedo Replicado

    E-print Network

    Duarte Jr., Elias Procópio

    -falha executando o algoritmo Hi-Dif, testa outro nodo do sistema para classificar seu estado. O modelo classifica-falha do sistema. Uma diferença fundamental do modelo proposto para outros modelos publicados anteriormenteDetecção Distribuída de Violação de Integridade em Sistemas com Conteúdo Replicado Roverli Pereira

  7. EM International. Volume 1

    SciTech Connect

    Not Available

    1993-07-01

    It is the intent of EM International to describe the Office of Environmental Restoration and Waste Management`s (EM`s) various roles and responsibilities within the international community. Cooperative agreements and programs, descriptions of projects and technologies, and synopses of visits to international sites are all highlighted in this semiannual journal. Focus on EM programs in this issue is on international collaboration in vitrification projects. Technology highlights covers: in situ sealing for contaminated sites; and remote sensors for toxic pollutants. Section on profiles of countries includes: Arctic contamination by the former Soviet Union, and EM activities with Germany--cooperative arrangements.

  8. Explorao do Espao de Projeto em Hw/Sw Co-design de Sistemas Tempo-Real Embarcados Orientados a Objetos: o

    E-print Network

    Wagner, Flávio Rech

    Exploração do Espaço de Projeto em Hw/Sw Co-design de Sistemas Tempo-Real Embarcados Orientados-real orientadas a objetos, executando em uma plataforma embarcada customizável. A plataforma alvo é um processador Java, o qual pode ser prototipado em FPGA. Um estudo de caso de implementação do escalonador de tarefas

  9. Deteco de Ativao em Ressonncia Nuclear Magntica Funcional do Crebro PEDRO PAULO DE M. OLIVEIRA JR

    E-print Network

    Detecção de Ativação em Ressonância Nuclear Magnética Funcional do Cérebro PEDRO PAULO DE M mapear áreas do cérebro em áreas do corpo é útil para se evitar que numa cirurgia no cérebro se extirpem resolução 128x128 em menos de 3 seg. A figura 1 mostra uma Imagem de ressonância magnética obtida com esta

  10. 21 CFR 520.1453 - Moxidectin and praziquantel gel.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...adults and L4 larval stages); hairworms: Trichostrongylus axei (adults); large-mouth stomach worms: Habronema muscae (adults); horse stomach bots: Gasterophilus intestinalis (2nd and 3rd instars) and G . nasalis (3rd...

  11. 21 CFR 520.1453 - Moxidectin and praziquantel gel.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...adults and L4 larval stages); hairworms: Trichostrongylus axei (adults); large-mouth stomach worms: Habronema muscae (adults); horse stomach bots: Gasterophilus intestinalis (2nd and 3rd instars) and G. nasalis (3rd...

  12. 21 CFR 520.1198 - Ivermectin and praziquantel paste.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...Hairworms (adults)—Trichostrongylus axei ; Large-mouth Stomach Worms (adults)—Habronema muscae ; Bots (oral and gastric...Hairworms (adults)—Trichostrongylus axei ; Large-mouth Stomach Worms (adults)—Habronema muscae ; Bots (oral and...

  13. 21 CFR 520.1198 - Ivermectin and praziquantel paste.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...Hairworms (adults)—Trichostrongylus axei ; Large-mouth Stomach Worms (adults)—Habronema muscae ; Bots (oral and gastric...Hairworms (adults)—Trichostrongylus axei ; Large-mouth Stomach Worms (adults)—Habronema muscae ; Bots (oral and...

  14. 21 CFR 520.1198 - Ivermectin and praziquantel paste.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...Hairworms (adults)—Trichostrongylus axei ; Large-mouth Stomach Worms (adults)—Habronema muscae ; Bots (oral and gastric...Hairworms (adults)—Trichostrongylus axei ; Large-mouth Stomach Worms (adults)—Habronema muscae ; Bots (oral and...

  15. 21 CFR 520.1198 - Ivermectin and praziquantel paste.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...Hairworms (adults)—Trichostrongylus axei ; Large-mouth Stomach Worms (adults)—Habronema muscae ; Bots (oral and gastric...Hairworms (adults)—Trichostrongylus axei ; Large-mouth Stomach Worms (adults)—Habronema muscae ; Bots (oral and...

  16. 21 CFR 520.1453 - Moxidectin and praziquantel gel.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...adults and L4 larval stages); hairworms: Trichostrongylus axei (adults); large-mouth stomach worms: Habronema muscae (adults); horse stomach bots: Gasterophilus intestinalis (2nd and 3rd instars) and G . nasalis (3rd...

  17. 21 CFR 520.1453 - Moxidectin and praziquantel gel.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...adults and L4 larval stages); hairworms: Trichostrongylus axei (adults); large-mouth stomach worms: Habronema muscae (adults); horse stomach bots: Gasterophilus intestinalis (2nd and 3rd instars) and G . nasalis (3rd...

  18. 21 CFR 520.1453 - Moxidectin and praziquantel gel.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...adults and L4 larval stages); hairworms: Trichostrongylus axei (adults); large-mouth stomach worms: Habronema muscae (adults); horse stomach bots: Gasterophilus intestinalis (2nd and 3rd instars) and G . nasalis (3rd...

  19. 21 CFR 520.1198 - Ivermectin and praziquantel paste.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...Hairworms (adults)—Trichostrongylus axei ; Large-mouth Stomach Worms (adults)—Habronema muscae ; Bots (oral and gastric...Hairworms (adults)—Trichostrongylus axei ; Large-mouth Stomach Worms (adults)—Habronema muscae ; Bots (oral and...

  20. 21 CFR 520.1871 - Praziquantel and pyrantel.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...tapeworms (Dipylidium caninum and Taenia taeniaeformis ), hookworms (Ancylostoma tubaeforme ), and large roundworms (Toxocara...roundworms (Toxocara canis and Toxascaris leonina ), hookworms (Ancylostoma caninum , Ancylostoma braziliense ,...

  1. 21 CFR 520.1871 - Praziquantel and pyrantel.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...tapeworms (Dipylidium caninum and Taenia taeniaeformis ), hookworms (Ancylostoma tubaeforme ), and large roundworms (Toxocara...roundworms (Toxocara canis and Toxascaris leonina ), hookworms (Ancylostoma caninum , Ancylostoma braziliense ,...

  2. 21 CFR 520.1445 - Milbemycin oxime and praziquantel.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...Dirofilaria immitis and for the treatment and control of adult roundworm (Toxocara canis, Toxascaris leonina ), adult hookworm (Ancylostoma caninum ), adult whipworm (Trichuris vulpis ), and adult tapeworm (Taenia pisiformis, Echinococcus...

  3. 21 CFR 520.903d - Febantel-praziquantel paste.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...Indications for use. (i) Dogs and puppies: For removal of hookworms (Ancylostoma caninum and Uncinaria stenocephala ), whipworms...pisiformis ). (ii) Cats and kittens: For removal of hookworms (Ancylostoma tubaeforme ), ascarids (Toxocara cati...

  4. 21 CFR 520.1200 - Ivermectin, fenbendazole, and praziquantel tablets.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...2) Indications for use . For the treatment and control of adult Toxocara canis (roundworm), Ancylostoma caninum (hookworm), Trichuris vulpis (whipworm), and Dipylidium caninum (tapeworm), and for the prevention of heartworm disease...

  5. 21 CFR 520.1200 - Ivermectin, fenbendazole, and praziquantel tablets.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...2) Indications for use . For the treatment and control of adult Toxocara canis (roundworm), Ancylostoma caninum (hookworm), Trichuris vulpis (whipworm), and Dipylidium caninum (tapeworm), and for the prevention of heartworm disease...

  6. 21 CFR 520.903d - Febantel-praziquantel paste.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...Indications for use. (i) Dogs and puppies: For removal of hookworms (Ancylostoma caninum and Uncinaria stenocephala ), whipworms...pisiformis ). (ii) Cats and kittens: For removal of hookworms (Ancylostoma tubaeforme ), ascarids (Toxocara cati...

  7. 21 CFR 520.1871 - Praziquantel and pyrantel.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...tapeworms (Dipylidium caninum and Taenia taeniaeformis ), hookworms (Ancylostoma tubaeforme ), and large roundworms (Toxocara...roundworms (Toxocara canis and Toxascaris leonina ), hookworms (Ancylostoma caninum , Ancylostoma braziliense ,...

  8. 21 CFR 520.1200 - Ivermectin, fenbendazole, and praziquantel tablets.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...2) Indications for use. For the treatment and control of adult Toxocara canis (roundworm), Ancylostoma caninum (hookworm), Trichuris vulpis (whipworm), and Dipylidium caninum (tapeworm), and for the prevention of heartworm disease...

  9. 21 CFR 520.1445 - Milbemycin oxime and praziquantel.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...Dirofilaria immitis and for the treatment and control of adult roundworm (Toxocara canis, Toxascaris leonina ), adult hookworm (Ancylostoma caninum ), adult whipworm (Trichuris vulpis ), and adult tapeworm (Taenia pisiformis, Echinococcus...

  10. 21 CFR 520.1871 - Praziquantel and pyrantel.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...tapeworms (Dipylidium caninum and Taenia taeniaeformis ), hookworms (Ancylostoma tubaeforme ), and large roundworms (Toxocara...roundworms (Toxocara canis and Toxascaris leonina ), hookworms (Ancylostoma caninum , Ancylostoma braziliense ,...

  11. 21 CFR 520.903d - Febantel-praziquantel paste.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...of paste per 7.5 pounds body weight) administered by mouth or in the food once daily for 3 days. (ii...gram of paste per 5 pounds body weight) administered by mouth on a full stomach once daily for 3 days. (2) Indications...

  12. Estudo e aplicação do código de desembaraçamento espectral - Korel - em sistemas triplos

    NASA Astrophysics Data System (ADS)

    Torres, K. B. V.; Vaz, L. P. R.

    2003-08-01

    O código KOREL é uma ferramenta adicional eficiente para a determinação simultânea de parâmetros orbitais espectroscópicos para o desembaraço de espectros individuais de sistemas estelares com até cinco componentes. Estudos já realizados (Torres,KBV,2002, Dissertação de Mestrado DF-ICEx-UFMG) mostram as limitações, aplicabilidade e eficiência do código para sistemas com duas componentes. Apresentamos, neste trabalho, a continuação dos estudos para sistemas com três componentes (sistemas hierárquicos), utilizando espectros sintéticos "gabaritos" de estrelas individuais em órbitas cujos parâmetros são conhecidos "a priori". Geramos os espectros compostos e verificamos como o código reproduz os parâmetros orbitais e espectros individuais em diversas situações físicas. É apresentado, ainda, uma discussão da aplicabilidade do código em sistemas reais como RV Crateris (Machado,ACM,1997, Dissertação de Mestrado DF-ICEx-UFMG), um sistema triplo cujas componentes eclipsantes estão, provavelmente, ainda na fase pré-sequência principal.

  13. Escenario EM Modelo Matematico

    E-print Network

    Majós, Antonio Badía

    j - 2012 CAB Escenario EM Modelo Matem´atico Problemas F´isicos Title Page 1 of 22 Back Full Screen.C.M.A.­C.S.I.C., Universidad de Zaragoza, ESPA~NA #12;j - 2012 CAB Escenario EM Modelo Matem´atico Problemas F´isicos Title negativa ? Difusi´on magn´etica hacia el EC #12;j - 2012 CAB Escenario EM Modelo Matem´atico Problemas F

  14. Deterministic annealing EM algorithm

    Microsoft Academic Search

    Naonori Ueda; Ryohei Nakano

    1998-01-01

    Abstract This paper presents a deterministic annealing EM (DAEM) algorithm for maximum,likelihood estimation problems,to overcome,a local maxima problem associated with the conventional EM algorithm. In our approach, a new posterior parameterized by ‘temperature’ is derived by using the principle of maximum entropy and is used for controlling the annealing process. In the DAEM algorithm, the EM process is reformulated as

  15. The Intermediate Polar EI UMa: A Prepolar Cataclysmic Variable

    NASA Astrophysics Data System (ADS)

    Reimer, Tamara W.; Welsh, William F.; Mukai, Koji; Ringwald, F. A.

    2008-05-01

    We present optical and X-ray time series photometry of EI UMa that reveal modulation at 746 and 770 s, which we interpret as the white dwarf spin and spin-orbit sidebands. These detections, combined with previous X-ray studies, establish EI UMa as an intermediate polar. We estimate the mass accretion rate to be ~3.6×1017 g s-1, which is close to, and likely greater than, the critical rate above which dwarf nova instabilities are suppressed. We also estimate the white dwarf to have a large magnetic moment ?>(3.4+/-0.2)×1033 G cm3. The high mass accretion rate and magnetic moment imply the existence of an accretion ring rather than a disk, and along with the relatively long orbital period, these suggest that EI UMa is a rare example of a prepolar cataclysmic variable.

  16. BZ UMa and Var Her 04: Orphan TOADS

    NASA Astrophysics Data System (ADS)

    Price, A.; Howell, S.

    2005-05-01

    Both BZ UMa and Var Her 04 are cataclysmic variable stars without a home. Neither fit easily into current classification systems so may extend the population distribution of two unique CV types: UGWZ dwarf novae and intermediate polars. New outburst photometry and archival X-Ray data shed some new light on BZ UMa's high energy state and new spectral and IR observations from Spitzer of dust around the newly discovered cataclysmic variable Var Her 04 may help find it a home as well.

  17. UFPR -Setor de Tecnologia DHS Programa de Ps Graduao em Engenharia de Recursos Hdricos e Ambiental Caixa Postal 19011 Jardim das Amricas 81531-990 Curitiba Paran fone-(41) 3361 3210 -fax 41-361 3143

    E-print Network

    Paraná, Universidade Federal do

    UFPR - Setor de Tecnologia ­ DHS ­ Programa de Pós Graduação em Engenharia de Recursos Hídricos e - fax 41-361 3143 http//www.tecnologia.ufpr.br/pos_dhs.br ­ pos.dhs@ufpr.br Curitiba, 16 de agosto de PPGERHA, pelo prêmio recebido em nome da prêmio Profissional ABES-PR 2009-2011. È uma honra para o DHS, o

  18. MESTRADO EM TEOLOGIA Edital 2015

    E-print Network

    MESTRADO EM TEOLOGIA Edital 2015 Este edital se destina especificamente a candidatos ao Mestrado em Teologia, com início em março de 2015. 1. Objetivo O Programa de Mestrado em Teologia visa o eclesiásticos. 2. Duração: 24 meses, iniciando-se em março de 2015 e concluindo-se em fevereiro de 2017. 3

  19. Equipment management system (EMS)

    Microsoft Academic Search

    T. Yurtsever; M. Comerford

    1995-01-01

    Equipment Management System (EMS) is a software tool used to monitor and track equipment states, restrictions and PM schedules in real time. EMS has been designed and customized to support the MOS-2 die production facility. The system provides graphical representation of the entire factory. Color coded icons represent equipment's current state (i.e. qualification, production, unscheduled maintenance, etc.). Preventative maintenance schedules

  20. Halema?uma?u Crater and Rock Fall Plume

    USGS Multimedia Gallery

    This image of a dusty plume produced by rocks collapsing from the wall of the eruptive vent within K?lauea Volcano’s Halema‘uma‘u Crater was captured by a USGS time-lapse camera on December 21, 2011.  Vigorous spattering on the lava lake deep within the vent created the o...

  1. Memory Systems for Cognitive Agents Uma Ramamurthy1

    E-print Network

    Ramamurthy, Uma

    Memory Systems for Cognitive Agents Uma Ramamurthy1 and Stan Franklin2 Abstract. The several different memory systems in human beings play crucial roles in facilitating human cognition. To build and cognitive science. In this paper we describe the various memory systems in the LIDA Architecture, which

  2. fGrin: um framework baseado em sistemas multi-agentes para formao de grupos de interesse a partir

    E-print Network

    Endler, Markus

    a massificação de compras on-line em relacionamentos business to business e business to consumer (Bailey e Bakos a contribuição individual de cada membro do grupo para o sucesso e evolução da educação neste tipo de ambiente prática permite agrupar consumidores para uma compra, respondendo assim às suas necessidades. No âmbito

  3. Relações solo-geoambiente em áreas de ocorrências de Ipucas na planície do Médio Araguaia - Estado de Tocantins

    Microsoft Academic Search

    Alan Kardec Elias Martins; Carlos Ernesto G. R. Schaefer; Elias Silva; Vicente Paulo Soares; Guilherme Resende Corrêa; Bruno Araújo Furtado de Mendonça

    2006-01-01

    RESUMO - Dentre as paisagens do médio rio Araguaia, destacam-se as extensas planícies e depressões sazonalmente alagadas. Nelas se inserem formações florestais higrófilas denominadas Ipucas, como enclaves peculiares pela sua fitossociologia e ambiente pedogeomorfológico. Esses fragmentos florestais naturais ocorrem na planície fluvial, em região de ecótono entre o Cerrado e a Floresta Amazônica. Neste estudo, foi selecionada uma área de

  4. Environmental Media Services (EMS)

    NSDL National Science Digital Library

    Environmental Media Services (EMS) is a nonprofit communications clearinghouse committed to the expansion of media coverage on critical environmental and public health issues. True to their mission, EMS staff "build relationships with top scientists, physicians, and other experts to bring journalists the latest and most credible information." EMS's modest homepage is free of clutter but full of content. While several sections are under construction and updates (currently) appear irregular, a series of available articles provides useful summaries of important environmental news issues over the past six months. Current articles include "The impacts of global warming on the oceans" and "Cool companies," among others.

  5. Código para imageamento indireto de estrelas em sistemas binarios: simulação de variações elipsoidais e do perfil das linhas

    NASA Astrophysics Data System (ADS)

    Souza, T. R.; Baptista, R.

    2003-08-01

    As estrelas secundárias em variáveis cataclí smicas (VCs) e binárias-x de baixa massa (BXBMs) são cruciais para o entendimento da origem, evolução e comportamento destas binárias interagentes. Elas são estrelas magneticamente ativas submetidas a condições ambientais extremas [e.g., estão muito próximas de uma fonte quente e irradiante; têm rotação extremamente rápida e forma distorcida; estão perdendo massa a taxas de 10-8-10-10 M¤/ano] que contribuem para que suas propriedades sejam distintas das de estrelas de mesma massa na seqüência principal. Por outro lado, o padrão de irradiação na face da secundária fornece informação sobre a geometria das estruturas de acréscimo em torno da estrela primária. Assim, a obtenção de imagens da superfície destas estrelas é de grande interesse astrofísico. A Tomografia Roche usa as variações no perfil das linhas de emissão/absorção da estrela secundária em função da fase orbital para mapear a distribuição de brilho em sua superfície. Neste trabalho apresentamos os resultados iniciais do desenvolvimento de um programa para o mapeamento da distribuição de brilho na superfí cie das estrelas secundárias em VCs e BXBMs com técnicas de astro-tomografia. Presentemente temos em operação um código que simula as variações no perfil das linhas em conseqüência de efeito Doppler resultante da combinação de rotação e translação de uma estrela em forma de lobo de Roche em torno do centro de massa da binária, em função da distribuição de brilho na superfície desta estrela. O código igualmente produz a curva de luz resultante das variações de aspecto da estrela em função da fase orbital (variações elipsoidais).

  6. Stability of the multiple star system ? UMa (ADS 7114)

    NASA Astrophysics Data System (ADS)

    Mel'nikov, A. V.; Orlov, V. V.; Shevchenko, I. I.

    2014-09-01

    The physical and orbital parameters of the quadruple star system ? UMa (HD 76644 = ADS 7114) were determined earlier, when it was concluded based on modeling the system's dynamics and applying theoretical stability criteria that the system was probably unstable. Here the stability of the ? UMa system is studied by calculating the Lyapunov characteristic exponents for representative sets of parameters and initial conditions. The conclusions on the system's stability (or instability) based on various stability criteria and the calculated Lyapunov exponents are compared. The instability of the system as a whole is confirmed rigorously based on massive computations of the Lyapunov exponents. This system appears to be the only known multiple system whose instability has been rigorously established. The Lyapunov time-disruption time statistical relations are constructed, which show that the Hamiltonian intermittency of the second kind dominates. Typical disruption times are shorter than 1000 years, and the Lyapunov times are shorter than 100 years.

  7. Neural network analysis of W UMa eclipsing binaries

    NASA Astrophysics Data System (ADS)

    Zeraatgari, F. Z.; Abedi, A.; Farshad, M.; Ebadian, M.; Riazi, N.

    2015-04-01

    We try five different artificial neural models, four models based on PNN (Perceptron Neural Network), and one using GRNN (Generalized Regression Neural Network) as tools for the automated light curve analysis of W UMa-type eclipsing binary systems. These algorithms, which are inspired by the Rucinski method, are designed and trained using MATLAB 7.6. A total of 17,820 generated contact binary light curves are first analyzed using a truncated cosine series with 11 coefficients and the most significant coefficients are applied as inputs of the neural models. The required sample light curves are systematically generated, using the WD2007 program (Wilson and Devinney 2007). The trained neural models are then applied to estimate the geometrical parameters of seven W UMa-type systems. The efficiency of different neural network models are then evaluated and compared to find the most efficient one.

  8. A Dynamical Analysis of the 47 UMa Planetary System

    E-print Network

    Gregory Laughlin; John Chambers; Debra Fischer

    2002-05-29

    The mass and period ratios of the two planets orbiting 47 UMa suggest a possible kinship to the Jupiter-Saturn pair in our solar system. We explore the current dynamical state of the 47 UMa system with numerical integrations, and compare the results with analytic secular theory. We find that the planets in the system are likely participating in a secular resonance in which the difference in the longitudes of pericenter librates around zero. Alternately, it is possible that the system is participating in the 7:3 mean motion resonance. We show that stability considerations restrict the mutual inclination between the two planets to 40 degrees or less, and that this result is relatively insensitive to the total mass of the two planets. We present hydrodynamical simulations which measure the torques exerted on the planets by a hypothesized external protoplanetary disk. We show that planetary migration in response to torques from the disk may have led to capture of the system into a 7:3 mean-motion resonance, although it is unclear how the eccentricities of the planets would have been damped after capture occured. We show that Earth-mass planets can survive for long periods in some regions of the habitable zone of the nominal co-planar system. A set of planetary accretion calculations, however, shows that it is unlikely that large terrestrial planets can form in the 47 UMa habitable zone.

  9. PROFESSOR DO SEPT MINISTRA CONFERNCIA EM ABERTURA EM CONGRESSO E SIMPSIO EM CARUARU

    E-print Network

    Paraná, Universidade Federal do

    PROFESSOR DO SEPT MINISTRA CONFER�NCIA EM ABERTURA EM CONGRESSO E SIMP�SIO EM CARUARU Christian Mendez Alcantara, Professor dos Cursos de Gestão Pública e Agente Comunitário em Saúde do Setor de ministrará conferência de abertura no evento: "Gestão e Governança em Saúde Pública: Avanços e Desafios" da

  10. A Evolução do Bestiário Letrado Medieval - uma síntese

    Microsoft Academic Search

    Pedro Chambel

    Na Idade Média, a natureza impunha-se à sociedade, marcando os seus ritmos, quotidianos e a própria sobrevivência das comunidades. Na verdade, a sociedade medieval, sendo maioritariamente rural, receava a natureza e as consequências muitas vezes negativas que ela podia trazer à estabilidade económica e social. Em grande parte temida, era por isso respeitada e sacralizada no âmbito duma mentalidade fundamentalmente

  11. PAREDES DE TEMPO: espaço e loucura em Fogo Morto de José Lins do Rego

    Microsoft Academic Search

    Por Aline de Paul; Nascimento Silva

    RESUMO: O romance Fogo morto, de José Lins do Rego, insere-se na tradição regionalista da literatura brasileira, fazendo parte do ciclo de romances da cana-de-açúcar e, por encerrar esse conjunto de romances, é tomado como uma obra síntese. Considerando o fato de que o regionalismo da década de 30, paradigma em que se encaixa a narrativa de José Lins do

  12. ESPECIAO ESPONTNEA EM POPULAES ESPACIALMENTE

    E-print Network

    de Aguiar, Marcus A. M.

    ESPECIA��O ESPONT�NEA EM POPULA��ES ESPACIALMENTE DISTRIBUÍDAS E PADR�ES DE DIVERSIDADE Elizabeth M público em geral. Em 1859 Charles Darwin deu passo fundamental para a solução desse problema com a dinâmica da enorme diversidade biológica existente em nosso planeta. Neste trabalho, discutimos um novo

  13. FUSE Observations of the Dwarf Nova SW UMa During Quiescence

    E-print Network

    M. S. Povich; J. C. Raymond; A. Lobel; K. Menou

    2004-09-24

    We present spectroscopic observations of the short-period cataclysmic variable SW Ursa Majoris, obtained by the Far Ultraviolet Spectroscopic Explorer (FUSE) satellite while the system was in quiescence. The data include the resonance lines of O VI at 1031.91 and 1037.61 A. These lines are present in emission, and they exhibit both narrow (~ 150 km/s) and broad (~ 2000 km/s) components. The narrow O VI emission lines exhibit unusual double-peaked and redshifted profiles. We attribute the source of this emission to a cooling flow onto the surface of the white dwarf primary. The broad O VI emission most likely originates in a thin, photoionized surface layer on the accretion disk. We searched for emission from H_2 at 1050 and 1100 A, motivated by the expectation that the bulk of the quiescent accretion disk is in the form of cool, molecular gas. If H_2 is present, then our limits on the fluxes of the H_2 lines are consistent with the presence of a surface layer of atomic H that shields the interior of the disk. These results may indicate that accretion operates primarily in the surface layers of the disk in SW UMa. We also investigate the far-UV continuum of SW UMa and place an upper limit of 15,000 K on the effective temperature of the white dwarf.

  14. Cincia feita em Portugal com

    E-print Network

    Instituto de Sistemas e Robotica

    Ciência feita em Portugal com mais impacto artigos As citações internacionais de artigos científicos produzidos em Portugal tiveram um "notório crescimento" nos últimos 23 anos, entre 1990 e 2012 das instituições nacionais tem progressivamente ganhado relevância. Um dado que surge numa altura em

  15. Característica de oferta de hortaliças sob a ótica do ambiente institucional: o caso das micro-bacias dos Córregos Bandeira e Segredo, em Campo Grande\\/MS

    Microsoft Academic Search

    Dario Oliveira Lima; Cristiane Mirian Carvalho; Kelly Wolff Cordeiro; Cicero Antonio Oliveira Tredezini

    2008-01-01

    O objetivo deste estudo é analisar as características da oferta de hortaliças nas micro-bacias Bandeira e Segredo com base na NEI. Para tanto foi feita uma pesquisa junto a 12 propriedades rurais. Os resultados mostram que os proprietários da bacia do Córrego Bandeira são, em sua maioria, comodatários que não consegue incentivo governamental por falta de comprovação de renda. Porém,

  16. The EM Earthquake Precursor

    NASA Astrophysics Data System (ADS)

    Jones, K. B., II; Saxton, P. T.

    2013-12-01

    Many attempts have been made to determine a sound forecasting method regarding earthquakes and warn the public in turn. Presently, the animal kingdom leads the precursor list alluding to a transmission related source. By applying the animal-based model to an electromagnetic (EM) wave model, various hypotheses were formed, but the most interesting one required the use of a magnetometer with a differing design and geometry. To date, numerous, high-end magnetometers have been in use in close proximity to fault zones for potential earthquake forecasting; however, something is still amiss. The problem still resides with what exactly is forecastable and the investigating direction of EM. After the 1989 Loma Prieta Earthquake, American earthquake investigators predetermined magnetometer use and a minimum earthquake magnitude necessary for EM detection. This action was set in motion, due to the extensive damage incurred and public outrage concerning earthquake forecasting; however, the magnetometers employed, grounded or buried, are completely subject to static and electric fields and have yet to correlate to an identifiable precursor. Secondly, there is neither a networked array for finding any epicentral locations, nor have there been any attempts to find even one. This methodology needs dismissal, because it is overly complicated, subject to continuous change, and provides no response time. As for the minimum magnitude threshold, which was set at M5, this is simply higher than what modern technological advances have gained. Detection can now be achieved at approximately M1, which greatly improves forecasting chances. A propagating precursor has now been detected in both the field and laboratory. Field antenna testing conducted outside the NE Texas town of Timpson in February, 2013, detected three strong EM sources along with numerous weaker signals. The antenna had mobility, and observations were noted for recurrence, duration, and frequency response. Next, two directional techniques were employed, resulting in three mapped, potential epicenters. The remaining, weaker signals presented similar directionality results to more epicentral locations. In addition, the directional results of the Timpson field tests lead to the design and construction of a third prototype antenna. In a laboratory setting, experiments were created to fail igneous rock types within a custom-designed Faraday Cage. An antenna emplaced within the cage detected EM emissions, which were both reproducible and distinct, and the laboratory results paralleled field results. With a viable system and continuous monitoring, a fracture cycle could be established and observed in real-time. Sequentially, field data would be reviewed quickly for assessment; thus, leading to a much improved earthquake forecasting capability. The EM precursor determined by this method may surpass all prior precursor claims, and the general public will finally receive long overdue forecasting.

  17. Recent developments on SU UMa stars - theory vs. observation

    NASA Astrophysics Data System (ADS)

    Cannizzo, John K.

    2015-01-01

    Kepler light curves of short period dwarf novae have resparked interest in the nature of superoutbursts and led to the question: Is the thermal-tidal instability needed, or can the plain vanilla version of the accretion disk limit cycle do the job all by itself? A detailed time-resolved study of an eclipsing SU UMa system during superoutburst onset should settle the question - if there is a dramatic contraction of the disk at superoutburst onset, Osaki's thermal-tidal model would be preferred; if not, the plain disk instability model would be su?cient. I will present recent results that support the contention by Osaki & Kato that the time varying negative superhump frequencies can be taken as a surrogate for the outer disk radius variations. Finally, it may be necessaryto look beyond the short period dwarf novae to gain perspective on the nature of embedded precursors in long outbursts.

  18. First photometric study of W UMa binary star LU Lac

    NASA Astrophysics Data System (ADS)

    Liao, W.-P.; Qian, S.-B.; Zhao, E.-G.; Jiang, L.-Q.

    2014-08-01

    LU Lac is a neglected W UMa binary star in photometric investigations. In this paper, we present BVRI CCD photometric light curves obtained on one night in 2012. The first photometric solutions of this system are computed by using the Wilson-Devinney code. It is shown that LU Lac is a marginal contact W-type system with a degree of contact factor of f=8.9%, a mass ratio of q=2.085 and a high inclination of i=82°.20. From the first analyses of orbital period changes, we found the period variation of the system includes an oscillation (A3=0.0125 days and T3=51.92 years). The cyclic change may be attributed to the light-travel time effect through the presence of a third body.

  19. Structure and evolution of low mass W UMa type systems

    E-print Network

    Lifang Li; Zhanwen Han; Fenghui Zhang

    2004-03-15

    The structure and evolution of low mass W UMa type contact binaries are discussed by employing Eggleton's stellar evolution code. Assuming that these systems completely satisfy Roche geometry, we calculate the relative radii of both components of contact binaries in different contact depth between inner and outer Roche lobes. We obtain a radius grid of contact binaries, and can ensure the surfaces of two components lying on an equipotential surface by interpolation using this radius grid when we follow the evolution of the contact binaries. We assume that the energy transfer takes place in the different regions of the common envelope to investigate the effects of the region of energy transfer on the structure and evolution of contact binaries. We find that the region of energy transfer has significant influence on the structure and evolution of contact binaries, and conclude that the energy transfer may occur in the outermost layers of the common convective envelope for W-type systems, and this transfer takes place in the deeper layers of the common envelope for A-type systems. Meanwhile, if we assume that the energy transfer takes place in the outermost layers for our model with low total mass, and find that our model steadily evolves towards a system with a smaller mass ratio and a deeper envelope, suggesting that some A-type W UMa systems with low total mass could be considered as the later evolutionary stages of W-subtype systems, and that the surface temperature of the secondary excesses that of the primary during the time when the primary expands rapidly, or the secondary contracts rapidly, suggesting that W-subtype systems may be caused by expansion of the primary, or by the contraction of the secondary.

  20. SISTEMA INTELIGENTE DE DESAFIOS ABERTOS - IOCS: Uma proposta de adaptação dos padrões do Método Clínico Piagetiano em Plataforma Multiagentes

    Microsoft Academic Search

    Othon C. Bastos Filho; Margarete Axt; Sofiane Labidi; Paloma D. Silveira; Andrei Rubina Thomaz

    The Intelligent Open Challenges System - IOCS is an intelligent system adapted by the theoretical contexts of the Piaget Clinical Method, in development for the Laboratory of Studies in Language, Interaction and Cognition - LELIC\\/UFRGS and the Intelligent Systems Laboratory - LSI\\/UFMA. Have as characteristics to simulate the role of experimenter and be a learning object, when is reutilized for

  1. Gestão do curso de Licenciatura em Pedagogia da UAB\\/UFSCar: tentativa de uma construção coletiva e dialógica

    Microsoft Academic Search

    Carolina Orquiza Cherfem; Ana Cláudia Inácio; Claudia Raimundo Reyes

    This paper has the objective to present the propos ed of coletive management of the graduate course of Graduate cours e in pedagogy in the Open University of Brazil, Federal University of São Car los - UAB \\/ UFSCar. This purpose is staff fundamentally in the dialogicidade and education theories and pratice of freedom in the vision of Paulo Freire.

  2. Avaliação quantitativa do conforto térmico de uma cidade em área de transição climática: Feira de Santana-Bahia, Brasil

    Microsoft Academic Search

    Rosângela Leal Santos; Henrique Oliveira de Andrade

    2008-01-01

    This article is an attempt to quantifying the thermal comfort of a city located in a transition area between the coastal humid climate and the semi-arid region of the northeastern Brazil. For this the Temperature Effective Index (TE) by Thom (1959) was used. The methodology is based on a discussion, followed by an analysis of the more important theories about

  3. UMA PROPOSTA PEDAGÓGICA PARA O USO DA MODELAGEM COMPUTACIONAL NO CURSO DE LICENCIATURA EM QUÍMICA DO CEFET CAMPOS

    Microsoft Academic Search

    Rodrigo Garrett da Costa

    This study presents an experiment on the use of a simulation and modelling computer environment in the teaching of Physical Chemistry. The research was conducted with students attending the Chemistry Teaching program at Cefet Campos aiming at: examining the contribution of using Modellus in the teaching and learning process, promoting a cooperative and collaborative learning environment among students, and observe

  4. Uma nova solução nutritiva para o cultivo de alface em hidroponia - sistema NFT, para as regiões litorâneas da região sudeste

    Microsoft Academic Search

    Gean Carlos; Silva Matias; Nilton Nélio Cometti; Wellington Mary

    An experiment was driven with lettuce vegetation home being tried 4 concentrations of nutritious solution, with the objective of to verify which would be the ideal concentration to be used in commercial cultivations in Rio de Janeiro and Espírito Santo. It can be concluded that the recommended concentration would be the one that adopted around 1 mS cm-1, even if

  5. Curso de Clculo de Uma Varivel x 4 (-1) n n!

    E-print Network

    Cabral, Marco

    Curso de Cálculo de Uma Variável d dx d dx d dx d dx # dx # dx # dx # dx sen x cos x - sen x - cos dx # dx d dx # dx Marco A. P. Cabral #12; ii #12; Curso de Cálculo de Uma Variável Primeira Edição V1 uma licença similar à presente. Ficha Catalográ#28;ca Cabral, Marco A. P. Curso de Cálculo de Uma

  6. V Seminário de Pesquisa em Turismo do MERCOSUL (SeminTUR) Turismo: Inovações da Pesquisa na América Latina Universidade de Caxias do Sul, RS, Brasil, 27 e 28 de Junho de 2008 Lazer, turismo e questões do patrimônio ambiental em áreas naturais: estudo de comparativo

    Microsoft Academic Search

    Edésio da Silva Santos

    Resumo Este trabalho tem o objetivo de fazer uma analise da importância das questões ambientais, vinculadas ao lazer e ao turismo sustentável em ambientes naturais no município de Pindamonhangaba, caracterizando a natureza destas atividades, verificando seus impactos e identificando possíveis ações planejadas que possam levar a um manejo equilibrado nestas áreas. Tendo como estudo de caso estas áreas naturais, o

  7. Semaine portes-ouvertes du DIMANCHE 11 au vendredi 16 JANVIER dans tous nos groupes d'arts martiaux! ACTIVIT CODE LUDIK NIVEAU HORAIRE LOCAL DURE EM M NM EM M NM EM M NM EM M NM EM M NM EM M NM

    E-print Network

    'arts martiaux! Remarques ACTIVITÉ CODE LUDIK NIVEAU HORAIRE LOCAL DURÉE EM M NM EM M NM EM M NM EM M NM EM M NM EM M NM Club d'Aïkido 02 020 0101 Débutant Lu 17h à 18h25 (cours) et Ve 18h30 à 20h25 (pratique ACTIVITÉ CODE LUDIK NIVEAU HORAIRE LOCAL DURÉE EM M NM EM M NM EM M NM EM M NM EM M NM EM M NM Club de

  8. Emergency Medicine Resident Involvement in EMS

    Microsoft Academic Search

    Adam M. Ray; David P. Sole

    2007-01-01

    Emergency Medical Services (EMS) activities are a required component of Emergency Medicine (EM) residency training. To determine resident involvement with EMS, all 135 Accreditation Council for Graduate Medical Education-accredited and 34 American Osteopathic Association-accredited EM residencies were surveyed in June 2005 regarding the EMS activities required of their residents. One hundred twelve surveys were completed (66% response rate). Observing with

  9. UMA ANÁLISE COMPARATIVA ENTRE OS CLUSTERS ECOLÓGICOS DA LAGOA RODRIGO DE FREITAS E DE BOULDER, COLORADO

    Microsoft Academic Search

    Andre Luiz Zopelari; Aldara da Silva Cesar; Marcio Lopes Pimenta; Dayanne Renata Timoteo Da Silva; Luis Otavio Salvador

    2008-01-01

    O propósito deste artigo é estabelecer uma comparação entre duas cidades importantes no cenário mundial de Clusters Ecológicos, no que se refere à geração de vantagens competitivas locais na Arena Competitiva dos Alimentos e Produtos Naturais e Orgânicos. Os resultados obtidos neste trabalho são decorrentes do emprego de uma visão teórica cunhada por Porter (1999) e complementada por Lima (2003)

  10. Uma Aula Prtica sobre LISP Siang Wun Song -Universidade de So Paulo -IME/USP

    E-print Network

    Song, Siang Wun

    Uma Aula Prática sobre LISP Siang Wun Song - Universidade de São Paulo - IME/USP MAC 5710 - Estruturas de Dados - 2008 Siang Wun Song - Universidade de São Paulo - IME/USP Uma Aula Prática sobre LISP #12;Linguagem LISP Surgiu no final dos anos 50 - John McCarthy (MIT). Linguagem para processamento

  11. DOUTORADO EM TEOLOGIA Edital 2014/02

    E-print Network

    DOUTORADO EM TEOLOGIA Edital 2014/02 Este edital se destina especificamente a candidatos ao Doutorado em Teologia, com início em agosto de 2014. 1. Objetivo: O Programa de Doutorado em Teologia visa o eclesiásticos. 2. Duração: 48 meses, com início em agosto de 2014 e término em julho de 2018. 3. Áreas de

  12. Identified EM Earthquake Precursors

    NASA Astrophysics Data System (ADS)

    Jones, Kenneth, II; Saxton, Patrick

    2014-05-01

    Many attempts have been made to determine a sound forecasting method regarding earthquakes and warn the public in turn. Presently, the animal kingdom leads the precursor list alluding to a transmission related source. By applying the animal-based model to an electromagnetic (EM) wave model, various hypotheses were formed, but the most interesting one required the use of a magnetometer with a differing design and geometry. To date, numerous, high-end magnetometers have been in use in close proximity to fault zones for potential earthquake forecasting; however, something is still amiss. The problem still resides with what exactly is forecastable and the investigating direction of EM. After a number of custom rock experiments, two hypotheses were formed which could answer the EM wave model. The first hypothesis concerned a sufficient and continuous electron movement either by surface or penetrative flow, and the second regarded a novel approach to radio transmission. Electron flow along fracture surfaces was determined to be inadequate in creating strong EM fields, because rock has a very high electrical resistance making it a high quality insulator. Penetrative flow could not be corroborated as well, because it was discovered that rock was absorbing and confining electrons to a very thin skin depth. Radio wave transmission and detection worked with every single test administered. This hypothesis was reviewed for propagating, long-wave generation with sufficient amplitude, and the capability of penetrating solid rock. Additionally, fracture spaces, either air or ion-filled, can facilitate this concept from great depths and allow for surficial detection. A few propagating precursor signals have been detected in the field occurring with associated phases using custom-built loop antennae. Field testing was conducted in Southern California from 2006-2011, and outside the NE Texas town of Timpson in February, 2013. The antennae have mobility and observations were noted for recurrence, duration, and frequency response. At the Southern California field sites, one loop antenna was positioned for omni-directional reception and also detected a strong First Schumann Resonance; however, additional Schumann Resonances were absent. At the Timpson, TX field sites, loop antennae were positioned for directional reception, due to earthquake-induced, hydraulic fracturing activity currently conducted by the oil and gas industry. Two strong signals, one moderately strong signal, and approximately 6-8 weaker signals were detected in the immediate vicinity. The three stronger signals were mapped by a biangulation technique, followed by a triangulation technique for confirmation. This was the first antenna mapping technique ever performed for determining possible earthquake epicenters. Six and a half months later, Timpson experienced two M4 (M4.1 and M4.3) earthquakes on September 2, 2013 followed by a M2.4 earthquake three days later, all occurring at a depth of five kilometers. The Timpson earthquake activity now has a cyclical rate and a forecast was given to the proper authorities. As a result, the Southern California and Timpson, TX field results led to an improved design and construction of a third prototype antenna. With a loop antenna array, a viable communication system, and continuous monitoring, a full fracture cycle can be established and observed in real-time. In addition, field data could be reviewed quickly for assessment and lead to a much more improved earthquake forecasting capability. The EM precursors determined by this method appear to surpass all prior precursor claims, and the general public will finally receive long overdue forecasting.

  13. Induction coilgun for EM mortar

    Microsoft Academic Search

    R. Kaye; B. Turman; M. Aubuchon; D. Lamppa; G. Mann; Edward van Reuth; K. Fulton; G. Malejko; P. Magnotti; D. Nguyen; D. Borgwarth; A. Johnson; R. Poppe

    2007-01-01

    The Defense Advanced Research Projects Agency is investigating electromagnetic (EM) guns for the next generation combat vehicle providing improved performance and survivability without the use of propellant. The two-year program was initiated in 2005 to design a coilgun and a railgun to launch an existing mortar round with an EM armature in laboratory conditions at speeds to increase range beyond

  14. CURSO DE ESPECIALIZAO EM FISIOTERAPIA

    E-print Network

    Floeter, Sergio Ricardo

    dois módulos no domingo e dois no Hospital Universitário em Florianópolis. LOCAL: Rua Pedro João. Enviar Documentação para: Universidade Federal de Santa Catarina - Campus Araranguá Rua Pedro João$ 425,00. Vencimento no 5º dia útil do mês. (1ª parcela em julho de 2012). PROGRAMA Virologia Genética

  15. ANÁLISE DA INSERÇÃO DOS TEMAS DE HUMANIDADES E ÉTICA, COM METODOLOGIA DE APRENDIZAGEM BASEADA EM PROBLEMAS, EM CURRICULO MÉDICO INTEGRADO EM ESCOLA PÚBLICA NO DISTRITO FEDERAL, BRASIL

    PubMed Central

    Novaes, Maria Rita Carvalho Garbi; Novaes, Luiz Carlos Garcez; Guilhem, Dirce; Lolas, Fernando; Silveira, Carla; Guiotti, Murilo

    2009-01-01

    Objetivo Realizar uma análise da inserção da ética e humanidades no currículo do Curso de Medicina da Escola Superior em Ciências da Saúde - ESCS, escola pública do Distrito Federal, Brasil, de forma a contribuir com o processo de gestão curricular. Metodologia O Estudo é de coorte e documental. Foram pesquisados 37 termos relacionados à ética e 36 referentes à humanização nos objetivos educacionais e conteúdo dos módulos temáticos, habilidades e atitudes e interação ensino-serviço-comunidade, de 1a a 4a série e no programa do internato no currículo (ano 2006) e no projeto pedagógico do Curso de Medicina (2001). Resultados Maior inserção da humanização, ética e bioética na 1a e 2a série, quando comparado à inserção na 3a e 4a série e no internato, (IC95%-?=0,034, pvalue=0,007). Unidade de habilidades e atitudes: freqüência das 3 temáticas no currículo da 1a a 4a séries (IC95%-?=0,026, pvalue=0,013). Quando comparada a inserção entre o internato e as quatro primeiras séries, observa-se que nestas a inserção da temática humanização é superior (IC95%-?=0,042, pvalue=0,029). Conclusão O currículo desenvolvido no ano de 2006 na ESCS apresentou correlação com o projeto pedagógico do curso e contemplou a temática de forma abrangente, em todas as séries e internato. PMID:20396594

  16. Fundamental data for contact binaries: RZ Comae, RZ Tauri, and AW UMa

    NASA Technical Reports Server (NTRS)

    Wilson, R. E.; Devinney, E. J.

    1972-01-01

    Differential corrections analyses of three W UMa type binaries show that RZ Tau and AW UMa have common envelopes and the relatively small gravity darkening predicted by Lucy, while RZ Comae seems to have a larger gravity effect and is only marginally in contact. Some details of the method for computing contact binary light curves are given. It is suggested that W UMa binaries which have occultation primary eclipses may, in general, have large amplitudes for gravity darkening or a photometric surface brightness effect which simulates large gravity darkening.

  17. College of Engineering EM Engineering Mechanics

    E-print Network

    MacAdam, Keith

    College of Engineering EM Engineering Mechanics KEY: # = new course * = course changed = course or concur: MA 213. EM 302 MECHANICS OF DEFORMABLE SOLIDS. (3 of Engineering or consent of chairperson, and EM 221; prereq or concur: MA 214. EM 313 DYNAMICS. (3

  18. Dicas para cruzeiros Todos os anos, milhes de cidados americanos saem em cruzeiros de frias. Em

    E-print Network

    Dicas para cruzeiros Todos os anos, milhões de cidadãos americanos saem em cruzeiros de férias. Em 2003, aproximadamente 8,3 milhões de passageiros embarcaram em diversos portos norte-americanos em cruzeiros de férias (fonte: Cruise Lines International Association). As viagens em navios de cruzeiro expõem

  19. Investigao em clulas estaminais no Biocant deu origem a cinco patentes em dois anos

    E-print Network

    Instituto de Sistemas e Robotica

    Investigação em células estaminais no Biocant deu origem a cinco patentes em dois anos A investigação em células estaminais (do cordão umbilical) no parque tecnológico Biocant, em Cantanhede, resultou, nos últimos dois anos, em cinco patentes, duas delas já licenciadas a empresas, disse à Lusa o

  20. Anlise do desmatamento em 2009, em especial em municpios e reas

    E-print Network

    em Outros Usos - 2.000 4.000 6.000 8.000 10.000 12.000 14.000 16.000 18.000 20.000 2001 2002 2003 desmatamento em Glebas - 2.000 4.000 6.000 8.000 10.000 12.000 14.000 16.000 18.000 20.000 2001 2002 2003 2004 2005 2006 2007 2008 2009 Histórico do desmatamento em Assentamentos - 2.000 4.000 6.000 8.000 10.000 12.000

  1. UMA WorldCat Sample Search 1 of 12| P a g e

    E-print Network

    Schweik, Charles M.

    terms into the provided search box. Hit the enter key or click on the "search" button to run your queryUMA WorldCat Sample Search 1 of 12| P a g e A t t a c h m e n t 1 o f : T e a c h i n g E n g l i H u t t o n In this guide you will find: UMA WorldCat description Conducting a simple search Finding

  2. Antimicrobial Activity of Pomegranate and Green Tea Extract on <em>Propionibacterium Acnes, Propionibacterium Granulosum, Staphylococcus Aureusem> and <em>Staphylococcus Epidermidisem>.

    PubMed

    Li, Zhaoping; Summanen, Paula H; Downes, Julia; Corbett, Karen; Komoriya, Tomoe; Henning, Susanne M; Kim, Jenny; Finegold, Sydney M

    2015-06-01

    We used pomegranate extract (POMx), pomegranate juice (POM juice) and green tea extract (GT) to establish in vitro activities against bacteria implicated in the pathogenesis of acne. Minimum inhibitory concentrations (MIC) of 94 <em>Propionibacterium acnes, Propionibacterium granulosum, Staphylococcus aureus,em> and <em>Staphylococcus epidermidisem> strains were determined by Clinical and Laboratory Standards Institute-approved agar dilution technique. Total phenolics content of the phytochemicals was determined using the Folin-Ciocalteu method and the polyphenol composition by HPLC. Bacteria were identified by 16S rRNA sequence analysis. GT MIC of 400 ?g/ml or less was obtained for 98% of the strains tested. 64% of <em>P. acnesem> strains had POMx MICs at 50 ?g/ml whereas 36% had MIC >400 ?g/ml. POMx, POM juice, and GT showed inhibitory activity against all the <em>P. granulosumem> strains at ?100 ?g/ml. POMx and GT inhibited all the <em>S. aureusem> strains at 400 ?g/ml or below, and POM juice had an MIC of 200 ?g/ml against 17 <em>S. aureusem> strains. POMx inhibited <em>S. epidermidisem> strains at 25 ?g/ml, whereas POM juice MICs were ?200 ?g/ml. The antibacterial properties of POMx and GT on the most common bacteria associated with the development and progression of acne suggest that these extracts may offer a better preventative/therapeutic regimen with fewer side effects than those currently available.

    <em>J Drugs Dermatolem>. 2015;14(6):574-578. PMID:26091382

  3. DWeb3D: Um toolkit para facilitar a criac~ao e manipulac~ao de cenas 3D em X3D Felipe Quintella

    E-print Network

    Barbosa, Alberto

    DWeb3D: Um toolkit para facilitar a criac¸~ao e manipulac¸~ao de cenas 3D em X3D Felipe Quintella@tecgraf.puc-rio.br Resumo O padr~ao X3D ´e uma soluc¸~ao aberta, suas qualidades e problemas s~ao discutidos e e a complexidade do X3D ao lidar com essas quest~oes. Como tentativa de demonstrar que al- gumas das

  4. MESTRADO EM MICROBIOLOGIA TAXONOMIA MICROBIANA Faculdade de Cincias

    E-print Network

    Instituto de Sistemas e Robotica

    MESTRADO EM MICROBIOLOGIA TAXONOMIA MICROBIANA ­ Faculdade de Ciências Objectivos: O principal e métodos utilizados em taxonomia microbiana (em particular de procariotas), encarada nas suas/diagnóstico utilizados actualmente em taxonomia bacteriana. Constituem objectivos adicionais a discussão da

  5. The Intermediate Polar EI UMa: A Pre-Polar Cataclysmic Variable

    E-print Network

    Tamara W. Reimer; William F. Welsh; Koji Mukai; F. A. Ringwald

    2008-02-24

    We present optical and X-ray time-series photometry of EI UMa that reveal modulation at 746 and 770 s, which we interpret as the white dwarf spin and spin-orbit sidebands. These detections, combined with previous X-ray studies, establish EI UMa as an intermediate polar. We estimate the mass accretion rate to be ~ 3.6 x 10^{17} g s^{-1}, which is close to, and likely greater than, the critical rate above which dwarf nova instabilities are suppressed. We also estimate the white dwarf to have a large magnetic moment mu > (3.4 +/- 0.2) x 10^{33} G cm^3. The high mass accretion rate and magnetic moment imply the existence of an accretion ring rather than a disk, and along with the relatively long orbital period, these suggest that EI UMa is a rare example of a pre-polar cataclysmic variable.

  6. ESTUDO DO MEIO EM UMESTUDO DO MEIO EM UM BAIRRO POPULAR NABAIRRO POPULAR NA

    E-print Network

    ESTUDO DO MEIO EM UMESTUDO DO MEIO EM UM BAIRRO POPULAR NABAIRRO POPULAR NA CIDADE DECIDADE DE DIDÁTICA EM QUE CONSITE O NOSSOEM QUE CONSITE O NOSSO PROJETO?PROJETO? MATERIAISMATERIAIS CAPACITAÇÃO PARTICIPATIVOORÇAMENTO PARTICIPATIVO #12;ALGUNS PROBLEMASALGUNS PROBLEMAS PROJETOS FUTUROSPROJETOS FUTUROS COORDENAÇÃO EM

  7. EM and Stochastic EM algorithms for reliability mixture models under random censoring

    E-print Network

    Paris-Sud XI, Université de

    EM and Stochastic EM algorithms for reliability mixture models under random censoring Laurent.chauveau@univ-orleans.fr April 6, 2012 Abstract We present in this paper several iterative methods based on EM and Stochas- tic EM methodology, that allow to estimate parametric or semiparametric mix- ture models for randomly

  8. Review -EM Waves Wavelengths of 108 to

    E-print Network

    Bertulani, Carlos A. - Department of Physics and Astronomy, Texas A&M University

    #12;Review - EM Waves EM Waves Wavelengths of 108 to 10-16 meters (10-1024 Hz) Traveling wave) given by BES rrr ×= 0 1 )(sin 111 22 0 2 00 tkxE c E c EBS m -=== Review - EM Waves 2 0 1 mpeak E c pr = c I pr = c I pr 2 = Total absorption Total reflection EM Waves: Radiation pressure #12;Source

  9. Ordem orientacional em sistemas com interaes competitivas

    E-print Network

    Stariolo, Daniel Adrián

    Ordem orientacional em sistemas com interações competitivas Daniel A. Stariolo Universidade Federal do Rio Grande do Sul 2012 i #12;Sumário 1 Ordem em sistemas de matéria condensada 1 1.1 Ordem posicional e orientacional em cristais líquidos, microemul- sões e copolímeros de dibloco

  10. PRMIO PRIMUS INTER PARES Construir em equipa

    E-print Network

    Instituto de Sistemas e Robotica

    PRÉMIO PRIMUS INTER PARES Construir em equipa as lideranças futuras 24 jovens testam competências na semifinal, em Peniche. Só um será o primeiro entre os seus pares Primeiro exercício da semifinal, como o imagi- nam. Como vão poder resumir o seu percurso profissional daqui a 25 anos, em 2038? Nas

  11. Pesquisas em Astrofsica no Oswaldo Duarte Miranda

    E-print Network

    Pesquisas em Astrofísica no INPE Oswaldo Duarte Miranda Divisão de Astrofísica ­ DAS #12 sua influência na magnetosfera terrestre. Abaixo: mapa do Sol em 22 GHz #12; Física do Meio Investigações são feitas através de observações em várias faixas do espectro eletromagnético, utilizandose

  12. Halibut/Sablefish EM Pilot Project

    E-print Network

    Halibut/Sablefish EM Pilot Project A Collaboration Involving: · Alaska Longline Fishermen's Assn · Engage stakeholders in developing a workable at-sea monitoring program · Field test EM hardware effective means of deploying EM hardware among vessels and retrieving data · Summarize study findings

  13. Segurana em Sistemas Distribudos confidencialidade

    E-print Network

    Rodriguez, Noemi

    chamada de segredo compartilhado · também chamada de criptografia simétrica criptografar texto chaves secretas · como fazer para as duas partes compartilharem um segredo? · uso de Key Distribution conceito com Diffie-Hellman, em 1976 ­ D-H apenas para estabelecimento de segredo compartilhado

  14. Pgina Inicial Empresas Start-ups portuguesas mostram-se hoje a investidores suecos em Lisboa Empresas criadas em

    E-print Network

    Instituto de Sistemas e Robotica

    Página Inicial Empresas Start-ups portuguesas mostram-se hoje a investidores suecos em Lisboa Empresas criadas em Portugal atingem as 31.400 em 2012 e superam... As empresas criadas em Portugal ascenderam a 31.400 em 2012, superando os... REGISTO | COMUNIDADE | Insolvência de empresas aumentou 41% em

  15. Aprovado pelo Colegiado do Curso de Ps-Graduao em Farmacologia em 16 de Julho de 1999. REGIMENTO DO CURSO DE PS-GRADUAO EM

    E-print Network

    Floeter, Sergio Ricardo

    Aprovado pelo Colegiado do Curso de Pós-Graduação em Farmacologia em 16 de Julho de 1999. REGIMENTO DO CURSO DE PÓS-GRADUAÇÃO EM FARMACOLOGIA DO CENTRO DE CIÊNCIAS BIOLÓGICAS DA UNIVERSIDADE FEDERAL DE SANTA CATARINA CAPÍTULO I SEÇÃO I DO OBJETIVO Art. 1o - O Curso de Pós-Graduação em Farmacologia em

  16. O que aconteceu uma fraco de segundo depois do Big Bang

    E-print Network

    Instituto de Sistemas e Robotica

    agora ter de confirmar dados D.R. #12;MARTA F. REIS mana, reis@ionline.pt Há 13,8 mil milhões de anos "inflação" ultra-rápi- da agora demonstrada, ajudou o í a per- ceber a relevância da descoberta, que ontem. Na radia- ção cósmica de fundo já havia pistas des- sa expansão mas agora percebeu-se que uma

  17. Uma equipa de investigadores portugueses pretende fazer o mapeamento 3D das Ilhas

    E-print Network

    Instituto de Sistemas e Robotica

    da Península Antártica. Na bagagem, leva um drone por Hugo Séneca m 50 anos, a temperatura média da cartografia de Marte, uma campanha de crowdfunding e um drone que promete acelerar a capacidade de mapeamento de um drone EBEE, da fabricante SenseFly, para o mapeamento 3D da península Antár- Os investigadores

  18. CHERN-SIMONS CLASSES FOR A SUPERCONNECTION JAYA NN IYER AND UMA N IYER

    E-print Network

    Iyer, Jaya N,

    CHERN-SIMONS CLASSES FOR A SUPERCONNECTION JAYA NN IYER AND UMA N IYER Abstract. In this note we define the Chern-Simons classes of a flat superconnection, D + L, on a complex Z/2Z-graded vector bundle. As an application, we obtain a definition of Chern-Simons classes of a (not necessarily flat) morphism between flat

  19. A EXTENSÃO OFICIAL NO BRASIL: UMA AVALIAÇÃO DIAGNÓSTICA. O CASO DO NORDESTE

    Microsoft Academic Search

    José Ribamar; Furtado de Souza

    Este trabalho é resultado de uma investigação sobre a ação dos órgãos oficiais de Assistência Técnica e Extensão rural (ATER) no nordeste brasileiro, com o objetivo avaliar as ações dos mesmos visando a implementação da nova Política Nacional de ATER (PNATER), na região como referência para o país. Ela contemplou os Estados de Bahia, Pernambuco, Paraíba, Rio Grande do Norte,

  20. Penso Concubina O Superior Tribunal de Justia negou a uma concubina o direito ao recebimento

    E-print Network

    Floeter, Sergio Ricardo

    Pensão Concubina O Superior Tribunal de Justiça negou a uma concubina o direito ao recebimento de companheira de homem casado, desde que separado de fato ou de direito, divorciado ou viúvo, o direito na://lfg.jusbrasil.com.br/noticias/966411/sexta-turma-do-stj-decide- concubina-nao-tem-direito-a-dividir-pensao-com-esposa #12;

  1. Política Fiscal Local e o Seu Papel Crescimento Econômico - Uma Evidência Empírica para o Brasil

    Microsoft Academic Search

    Cristiano Aguiar de Oliveira; Liderau dos Santos Marques Junior; Paulo de Andrade Jacinto

    2009-01-01

    Este artigo estuda o papel da política fiscal local no crescimento econômico de cidades. Para este fim, o artigo apresenta um modelo espacial de crescimento econômico com governo, que incorpora as contribuições das teorias do crescimento endógeno e da nova geografia econômica. O modelo _e avaliado empiricamente através de uma aplicação para as cidades brasileiras na década de noventa. Os

  2. Angus Robichaud's Reel G Em D A Bm D7

    E-print Network

    Doyle, Peter

    Angus Robichaud's Reel 4 4 D G A D D G A D 3 3 G Em D A Bm D7 3 3 G Em D A D Animas Reel Bernie Waugh 4 4 3 3 G D G Bm Em C Am C D G D G Bm Em C Am D G The Arkansas Traveler 4 2 D G A D Em A 3 D G A D Em G A D D G D A Bm Em A D G D A Em G A D #12; Asher Rodney Miller 4 4 D Em F#m G A D Em G A D A D 1

  3. Angus Robichaud's Reel G Em D A Bm D7

    E-print Network

    Doyle, Peter

    Angus Robichaud's Reel 4 4 D G A D D G A D 3 3 G Em D A Bm D7 3 3 G Em D A D Animas Reel Bernie Waugh 4 4 3 3 G D G Bm Em C Am C D G D G Bm Em C Am D G The Arkansas Traveler 4 2 D G A D Em A 3D G A D Em G A D D G D A Bm Em A D G D A Em G A D #12;Asher Rodney Miller 4 4 D Em F#m G A D Em G A D A D1 2

  4. Development of an EMS curriculum.

    PubMed

    Brice, Jane H; Perina, Debra G; Liu, J Marc; Braude, Darren A; Rinnert, Kathy J; MacDonald, Russell D

    2014-01-01

    Emergency medical services (EMS) became an American Board of Medical Specialties (ABMS) approved subspecialty of emergency medicine in September 2010. Achieving specialty or subspecialty recognition in an area of medical practice requires a unique body of knowledge, a scientific basis for the practice, a significant number of physicians who dedicate a portion of their practice to the area, and a sufficient number of fellowship programs. To prepare EMS fellows for successful completion of fellowship training, a lifetime of subspecialty practice, and certification examination, a formalized structured fellowship curriculum is necessary. A functional curriculum is one that takes the entire body of knowledge necessary to appropriately practice in the identified area and codifies it into a training blueprint to ensure that all of the items are covered over the prescribed training period. A curriculum can be as detailed as desired but typically all major headings and subheadings of the core content are identified and addressed. Common curricular components, specific to each area of the core content, include goals and objectives, implementation methods, evaluation, and outcomes assessment methods. Implementation methods can include simulation, observations, didactics, and experiential elements. Evaluation and outcomes assessment methods can include direct observation of patient assessment and treatment skills, structured patient simulations, 360° feedback, written and oral testing, and retrospective chart reviews. This paper describes a curriculum that is congruent with the current EMS core content, as well as providing a 12-month format to deploy the curriculum in an EMS fellowship program. Key words: curriculum; education; emergency medical services; fellowships and scholarships. PMID:24156509

  5. Complaints against an EMS system.

    PubMed

    Colwell, Christopher B; Pons, Peter T; Pi, Randy

    2003-11-01

    Complaints against Emergency Medical Services (EMS) agencies represent a concerning and potentially time-consuming problem for all involved in the delivery of prehospital emergency medical care. The objective of this study was to identify the source of complaints against an EMS system to help focus quality and performance improvement and customer service efforts. We conducted a retrospective review of complaints filed against a busy urban EMS agency over a 6-year period. All complaints were included, totaled by season and by year, and categorized by originator and nature of the complaint. A total of 286 complaints were registered during the 6-year period, with an average of 48 per year and 9.3 per 10,000 responses. The most common originators of complaints were patients (53%) followed by medical personnel (19%) and family members or friends (12%). Rude behavior accounted for 23% of the complaints registered, followed by technical skills (20%), transport problems (18%), and loss of belongings (13%). The identification of areas of dissatisfaction will allow focused quality and performance improvement programs directed at customer service and risk management. PMID:14654181

  6. 21 CFR 520.1872 - Praziquantel, pyrantel pamoate, and febantel tablets.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...Indications for use. For the removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus ); hookworms (Ancylostoma caninum, Uncinaria stenocephala ); ascarids (Toxocara canis, Toxascaris leonina ); and...

  7. 21 CFR 520.1872 - Praziquantel, pyrantel pamoate, and febantel tablets.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...Indications for use . For the removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus ); hookworms (Ancylostoma caninum, Uncinaria stenocephala ); ascarids (Toxocara canis, Toxascaris leonina ); and...

  8. 21 CFR 520.1872 - Praziquantel, pyrantel pamoate, and febantel tablets.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...Indications for use . For the removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus ); hookworms (Ancylostoma caninum, Uncinaria stenocephala ); ascarids (Toxocara canis, Toxascaris leonina ); and...

  9. 21 CFR 520.1447 - Milbemycin oxime, lufenuron, and praziquantel tablets.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...of heartworm disease caused by Dirofilaria immitis; for the prevention and control of flea populations (Ctenocephalides felis ); and for the treatment and control of adult roundworm (Toxocara canis, Toxascaris leonina ), adult...

  10. 21 CFR 520.1447 - Milbemycin oxime, lufenuron, and praziquantel tablets.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...of heartworm disease caused by Dirofilaria immitis; for the prevention and control of flea populations (Ctenocephalides felis ); and for the treatment and control of adult roundworm (Toxocara canis, Toxascaris leonina ), adult...

  11. 21 CFR 520.1447 - Milbemycin oxime, lufenuron, and praziquantel tablets.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...of heartworm disease caused by Dirofilaria immitis; for the prevention and control of flea populations (Ctenocephalides felis ); and for the treatment and control of adult roundworm (Toxocara canis, Toxascaris leonina ), adult...

  12. POLMEROS EM SUPERFCIES Polmeros adsorvidos na superfcies de partculas

    E-print Network

    Loh, Watson

    POLÍMEROS EM SUPERFÍCIES Polímeros adsorvidos na superfícies de partículas coloidais Polímeros em interfaces líquidas Polímeros em interfaces sólidas #12;Polímeros em solução - Teoria de Flory-Hugghins #12;Polímeros em solução - Teoria de Flory-Hugghins Gm = kT(1ln1 + 2/N ln2 + 12) 1 = solvente 2 = polímero (Gm

  13. Random swap EM algorithm for Gaussian mixture models Qinpei Zhao

    E-print Network

    Joensuu, University of

    Random swap EM algorithm for Gaussian mixture models Qinpei Zhao , Ville Hautamäki, Ismo. Borgefors Keywords: Expectation maximization Random swap EM Gaussian mixture model Split and merge EM Genetic-based EM Data clustering a b s t r a c t Expectation maximization (EM) algorithm is a popular way

  14. CURSO DE PS-GRADUAO EM ENGENHARIA E TECNOLOGIA ESPACIAIS

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE CONCENTRAÇÃO EM CIÊNCIA E, França, 2003 #12;2 CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE CONCENTRAÇÃO EM para o Mestrado (*) CMS-207-4 Técnicas Experimentais em Ciência dos Materiais I CMS-300-4 Mecânica

  15. Accretion disk of the cataclysmic variable IY UMa in quiescence and its active state

    NASA Astrophysics Data System (ADS)

    Khruzina, T. S.; Katysheva, N. A.; Shugarov, S. Yu.

    2008-10-01

    We present the results of a study of the eclipsing binary IY UMa (type SU UMa) during its superoutburst of 2004 and in quiescence.We have refined the orbital period of the system. Light curves are presented for various states of activity.We estimate the parameters of IYUMa during the superoutburst and in quiescence for hot-line and spiral-wave models. The spiral-wave model, which takes into account the presence of vertical perturbations in outer parts of the disk, is able to reproduce the light-curve shapes and phases of dips in the out-of-eclipse parts of the binary’s light curves during the outburst both qualitatively and quantitatively.

  16. Increasing Supercycle Lengths of Active SU UMa-type Dwarf Novae

    NASA Astrophysics Data System (ADS)

    Otulakowska-Hypka, M.; Olech, A.

    2014-12-01

    We present observational evidence that supercycle lengths of the most active SU UMa-type stars are increasing during the past decades. We analyzed a large number of photometric measurements from available archives and found that this effect is generic for this class of stars, independently of their evolutionary status. This finding is in agreement with previous predictions and the most recent work of Patterson et al. (2012) on BK Lyn.

  17. UMA-OYA UPPER WATERSHED MANAGEMENT PROJECT (UWMP) IN SRI LANKA: THE IMPACTS AT HOUSEHOLD LEVEL

    Microsoft Academic Search

    J. M. U. I. Jayaweera; Mangala De Zoysa; Dayananda Kariyawasam

    The Uma-Oya Upper Watershed Management Project (UWMP) was implemented through training and helping households to conserve natural resources. However, the project has not signifi cantly changed the socio-economic status of the households. Many households' (63%) primary occupation is farming, 21% are illiterate and 31% have primary education. They possess an average of 0.4 ha, either as owned lands (32%), encroached

  18. Col^onia de Formigas: Uma Abordagem Para Resoluc~ao De Problemas De Layout

    E-print Network

    Gomes, Francisco A. M.

    Col^onia de Formigas: Uma Abordagem Para Resolu¸c~ao De Problemas De Layout Daniele Costa Silva formigas e propomos seu uso para resolu¸c~ao de problemas de layout. Palavras-Chaves. Col^onia de Formigas. Problemas de Layout. M´etodos Heur´isticos. 1 Introdu¸c~ao O problema de layout ´e um problema antigo e ap

  19. Lietuvos teritorijos žem?s plutos deformacij? ir seismotektoninio potencialo ryšys

    NASA Astrophysics Data System (ADS)

    Zakarevi?ius, Algimantas; Stanionis, Arminas; Levinskait?, Daiva

    2010-01-01

    Lietuvoje yra statini?, kelian?i? ekologinio pavojaus gr?sm? (Ignalinos atomin? elektrin?, Mažeiki? naftos perdirbimo ?mon?, chemijos gamyklos Jonavoje bei K?dainiuose ir pan.). Seisminiai ?vykiai gali sutrikdyti ši? ?moni? veikl? ir net lemti didel? pavoj? aplinkai, t. y. gali b?ti sukelta didel? aplinkos tarša chemin?mis bei radioaktyviosiomis medžiagomis. Seisminius ?vykius lemia teritorijos seismotektoninis potencialas. Seismotektoninis potencialas ir Žem?s plutos deformacijos yra tarpusavyje susij? rei\\vskiniai, kuriuos sukelia dažnai tie patys giluminiai procesai Žem?s gelm?se. Žem?s plutos deformacij? tyrimas yra vienas iš informacijos šaltini? prognozuojant teritorijos seismotektonin? aktyvum?. Straipsnyje nagrin?jamos Žem?s plutos horizontaliosios deformacijos, nustatomi Žem?s plutos ?tempi? poky?iai Lietuvos teritorijoje pagal GPS matavim? duomenis. Atlikus tyrimus pagal pateikiam? Žem?s plutos horizontali?j? deformacij? ir ?tempi? tyrimo metodik?, gauti nauji horizontali?j? deformacij? charakteristik? bei ?tempi? poky?i? rezultatai ir nustatytos j? s?sajos su seismotektoniniu potencialu.

  20. Servidor tem direito a licena para acompanha cnjuge aprovado em concurso em outro estado

    E-print Network

    Floeter, Sergio Ricardo

    Servidor tem direito a licença para acompanha cônjuge aprovado em concurso em outro estado O servidor público tem direito a licença para acompanhamento do cônjuge se este for aprovado em concurso Federal da 4ª Região (TRF4), o tribunal concedeu apenas o direito a licença não-remunerada, mas não

  1. Photometric Observations of an SU UMa-type Dwarf Nova VW Coronae Borealis during Outbursts

    E-print Network

    D. Nogami; M. Uemura; R. Ishioka; T. Kato; J. Pietz

    2003-12-31

    We report the photometric observations of an SU UMa-type dwarf nova VW CrB during two superoutbursts in 2001 and 2003 and a normal outburst in 2003. Superhumps with a period of 0.07287(1) d were observed during the 2003 superoutburst. The change rate of the superhump period was positive. During the normal outburst, there are some hint of modulation up to a 0.2-mag amplitude. However, any periodicity was not found. The recurrence cycles of the normal outburst and the superoutburst, and the distance were estimated to be > ~50 d, 270-500 d, and 690(+230, -170) pc, respectively. These recurrence cycles are usual values for an SU UMa-type dwarf nova having this superhump period. The superhump period of VW CrB was the longest among those of the SU UMa stars with positive derivatives of the superhump period. The coverage of our observations was, however, not enough, and the variation of the Psh change rate of VW CrB is still unknown. A superhump regrowth and a brightening were seen near the end of the plateau phase. Measuring the deviation of the start timings of the brightening and the superhump regrowth (>2 days in VW CrB) will be a key to reveal the mechanism of these phenomena.

  2. Disperses leo em gua (o/w) ou gua em leo (w/o) Fase contnua / fase dispersa.

    E-print Network

    Loh, Watson

    Emulsões Dispersões óleo em água (o/w) ou água em óleo (w/o) Fase contínua / fase dispersa. Agente solubilidade da fase dispersa em gotas menores - "Ostwald Ripening" ­ mais pronunciado em fases mais miscíveis) ­ SLES/betaína (b)- inverso #12;3. Barreira eletrostática ou estérica Repulsão eletrostática em

  3. Em 1959 cursava o terceiro colegial no Julinho em Porto Alegre, onde recebi o folheto "Voc tem pensado em fsica?" que mais tarde soube ter sido produzido

    E-print Network

    dos Santos, C.A.

    Em 1959 cursava o terceiro colegial no Julinho em Porto Alegre, onde recebi o folheto "Você tem pensado em física?" que mais tarde soube ter sido produzido pelo Darcy. Estava indeciso entre física e som e a cores a bela tarde em que, dentro de um bonde Petrópolis, passando pela Protásio diante do

  4. Construc~ao Observavel de um Quorum de Nos N~ao-Sybil na Vizinhanca Radio de uma Rede Ad Hoc Sem Fios

    E-print Network

    Rodrigues, Luís E.T.

    Construc¸~ao Observ´avel de um Quorum de N´os N~ao-Sybil na Vizinhanc¸a R´adio de uma Rede Ad Hoc Quorum N~ao-Sybil (QNS), numa vizinhanc¸a r´adio de uma rede ad hoc sem fios (i.e. uma rede com um ´unico

  5. O ESPAÇO DA UVA TRANSFORMADO EM AGRONEGÓCIO

    Microsoft Academic Search

    Mariza Cezira Campagner; Gervasio Castro de Rezende

    2008-01-01

    O presente artigo tem por objetivo apresentar algumas das redefinições do trabalho agrícola resultantes do processo de reestruturação do espaço da uva transformado em agronegócio, no qual se tem expandido o agronegócio de frutas tropicais. A metodologia está organizada em torno de atualização da pesquisa bibliográfica e as temáticas de interesse; realização de trabalhos na área de estudo. Conclui que

  6. CURSO DE PS-GRADUAO EM METEOROLOGIA

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM METEOROLOGIA Coordenador Acadêmico Dirceu Luis Herdies Membros do Conselho de Curso Luis Gustavo Gonçalves de Gonçalves José Antonio Marengo Orsini Clóvis Angeli Sansigolo Innocentini, Ph.D., Univ. of Reading, 1986 #12;2 CURSO DE PÓS-GRADUAÇÃO EM METEOROLOGIA PROGRAMAÇÃO ANUAL DAS

  7. CURSO DE PS-GRADUAO EM METEOROLOGIA

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM METEOROLOGIA Coordenadora Acadêmica Maria Paulete Pereira Martins Membros do Conselho de Curso Dirceu Luis Herdies Luis Gustavo Gonçalves de Gonçalves José Antonio Marengo., 1969 Valdir Innocentini, Ph.D., Univ. of Reading, 1986 #12;2 CURSO DE PÓS-GRADUAÇÃO EM METEOROLOGIA

  8. Tendências De Teses e Dissertações Sobre Educação em Astronomia No Brasil

    NASA Astrophysics Data System (ADS)

    Bretones, Paulo Sergio; Megid Neto, Jorge

    2005-07-01

    Apresentam-se os resultados de uma pesquisa do tipo estado da arte sobre teses e dissertações defendidas no Brasil e relativas ao ensino de Astronomia, com objetivo de identificar essa produção e conhecer as principais tendências da pesquisa nesse campo. Foram localizadas 13 dissertações de mestrado e 3 teses de doutorado, as quais foram estudadas em função dos seguintes aspectos: isntituição, ano de defesa, nível escolar abrangido no estudo, foco temático do estudo e gênero de trabalho acadêmico. Pretende-se assim colaborar com a divulgação ampla da produção acadêmica na área. Ao mesmo tempo o estudo possibilita, a partir de investigações decorrentes, apontar as contribuições dessa produção para o ensino e sinalizar com necessidades a serem supridas por futuras pesquisas.

  9. TR-IIS-07-012 aEM: Targeted Aggressive

    E-print Network

    Chen, Sheng-Wei

    . (1997) proposed the parameterized EM (pEM) algorithm to accelerate EM for Bayesian Networks, and Luis and Leslie (1999) applied pEM for Mixtures of Gaussians. The pEM algorithm accelerates the convergence . They showed that pEM converges faster than EM and the convergence is guaranteed when 1 pEM

  10. Escolas, Qualidade Ambiental e Educação no Brasil: Uma Contextualização Histórica 1

    Microsoft Academic Search

    Giselle Arteiro; Nielsen Azevedo

    O inventário do repertório tipológico das edificações escolares no Brasil tem demonstrado que o projeto padrão sempre esteve presente nas soluções adotadas, desde as primeiras unidades projetadas especificamente para fins educacionais, no início da República, até os dias de hoje. Em cada momento histórico, essas edificações materializaram as práticas pedagógicas e as políticas públicas educacionais vigentes, comungando com o próprio

  11. OS ANOS DOURADOS DO CAPITALISMO: UMA TENTATIVA DE HARMONIZAÇÃO ENTRE AS CLASSES1

    Microsoft Academic Search

    PAULO BALANCO; EDUARDO COSTA PINTO

    Resumo: Este artigo discute o padrão de acumulação dos anos dourados, procurando situá-lo como resultados do processo dialético das leis de movimento do valor. Nesse sentido, as transformações econômicas, culturais e institucionais dos anos dourados, mediante as quais foram concedidos certos benefícios à classe trabalhadora funcionaram com estratégias defensivas do capital diante da crise de dominação provocada, em grande medida,

  12. AGRICULTURA FAMILIAR E SUSTENTABILIDADE SOCIOAMBIENTAL: UMA RELAÇÃO DE TRABALHO E PODER

    Microsoft Academic Search

    Marilanda Jesus de Lima; Anderson Alves Santos; Lúcia Gracia Ferreira; Guerra Ferreira; Ineis Ferraz da Silva; Valdeni de Jesus Almeida

    Resumo : Durante décadas presenciamos a importância da agricultura familiar no contexto agropecuário brasileiro. A agricultura familiar proporciona a permanência do homem no campo, geração de renda e sustentabilidade ambiental através da agroecologia. Se levarmos em consideração o local onde a agricultura familiar acontece perceberemos que ela está vinculada a sustentabilidade socioambiental, ligadas as relações de trabalho e poder. Assim,

  13. Totem e Tabu: Uma reflexão sobre o Complexo de Édipo na origem da civilização

    Microsoft Academic Search

    Josefa D. D. de Carvalho

    2002-01-01

    Resumo A decisão pela escolha deste tema, se deu a partir do interesse despertado nas apresentações e discussões em sala de aula sobre o texto Totem e Tabu. Para tanto, foi feito um recorte na teoria freudiana de um dos seus conceitos mais importante: o Complexo de Édipo. Este, segundo Freud, parece apontar para a possibilidade da sua existência na

  14. M em ory for Item s and M em ory for R elations in the Procedural/D eclarative M em ory Fram ew ork

    E-print Network

    Poldrack, Russ

    M em ory for Item s and M em ory for R elations in the Procedural/D eclarative M em ory Fram ew ork ard Eichenbaum Boston U niversity, U SA A m ajor area of research in m em ory and am nesia concerns the item specificity of im plicit m em ory. In this paper w e address several issues about the nature of im

  15. INFLUÊNCIA DO TIPO DE VEGETAÇÃO NAS POPULAÇÕES DE AVES EM UMA FLORESTA IMPLANTADA DE Pinus spp, NA REGIÃO DE AGUDOS, SP

    Microsoft Academic Search

    Alvaro Fernando de Almeida

    O. D. C. 156:174.7 Pinus spp SUMMARY The author studied a bird community through the capture marking and recapture in a man made Pinus forest. The populations were compared in the internal natural vegetations, in the man made Pinus and native species forests and in the external («cerrado»). The birds penetration in the man made forests is discussed according to

  16. artigo original Substituição da Insulina NPH por Insulina Glargina em Uma C o o rte de Pacientes Diabéticos: Estudo Observa c i o n a l

    Microsoft Academic Search

    FREDERICOF. R. MAIA; Universitário São José

    2007-01-01

    Switching of NPH Insulin to Glargine Therapy in a Cohort of Poorly Con- trolled Diabetic Patients: Observational Study. This study examined the impact of insulin glargine introduction in basal-bolus thera- py in type 1 and type 2 diabetic patients with inadequate metabolic control (A1c > 6.9%) using previous NPH insulin regime. In this uncontrolled, retrospective study, 49 patients (28F\\/21M), average

  17. Urinary sepsis in children: a systematic review of diagnostic and therapeutic aspects Infecção urinária em crianças: uma revisão sistemática dos aspectos diagnósticos e terapêuticos

    Microsoft Academic Search

    Marco Antonio Arap; Eduardo Juan Troster

    During the last decade, new imaging techniques and biological probes provided further insight into the pathogenesis and natural history of urinary tract infection (UTI) in children. Especially in newborns, UTI is a common cause of fever and probably the most common cause of renal parenchymal loss. In children aged equal or less than 2 years, the symptoms of UTI are

  18. Floração de cianobactérias tóxicas em uma lagoa costeira hipereutrófica do Rio de Janeiro\\/RJ (Brasil) e suas consequências para a saúde humana

    Microsoft Academic Search

    Andreia Maria da Anunciação Gomes; Pedro Lima Sampaio; Aloysio da Silva Ferrão-Filho; Valeria de Freitas Magalhães; Marcelo Manzi Marinho; Ana Cláudia Pimentel Oliveira; Vitor Barbosa Santos; Patrícia Domingos; Sandra Maria Feliciano de Oliveira Azevedo

    2009-01-01

    TOXIC CYANOBACTERIAL BLOOMS IN AN EUTROPHICATED COASTAL LAGOON IN RIO DE JANEIRO, BRAZIL: EFFECTS ON HUMAN HEALTH. The Jacarepaguá Basin, Rio de Janeiro, Brazil has over the last four decades undergone a disordered process of urban and industrial growth with direct consequences on water quality and incidence of cyanobacterial blooms in the Jacarepaguá Lagoon Complex (JLC). The present study combines

  19. Composição florística e estrutura comunitária de epífitos vasculares em uma floresta de galeria na Depressão Central do Rio Grande do Sul1

    Microsoft Academic Search

    CLAUDIA GIONGO; JORGE L. WAECHTER

    Floristic composition and community structure of vascular epiphytes in a gallery forest of the Central Depression of Rio Grande do Sul). Although gallery forests are widespread throughout the neotropics, little information is available about vascular epiphytism in these formations. The objective of this study was to describe the floristic composition and community structure of vascular epiphytes in a gallery forest

  20. Detecção de assentamentos irregulares em áreas de risco e classificação das habitações utilizando imagens anaglifo - uma forma de apoiar o planejamento urbano

    Microsoft Academic Search

    Carlos Alberto; Borba Schuler

    The difficulty of the quantification of the irregular occupations leads the search of new procedures to indicate its perimeters and to distinguish the property. Normally this quantification is carried through directly in field, however the displacement inside of these areas is difficult because the community does not see with good eyes the circulation of strangers in its space. One in

  1. Uma proposta de metodologia para adaptação de OA usando critérios de acessibilidade Cristiani de Oliveira Dias - Programa de Pós-Graduação em Educação - cristianideoliveiradias@gmail.com

    Microsoft Academic Search

    Liliana Maria Passerino

    The intent of this paper is to study the learning objects from another perspective, be available in its content and format for all the people \\/ citizens, having special needs or not. Therefore, it is planned to build a methodology for developing object oriented software following the fusion method that facilitates the development of learning objects. Throughout the text we

  2. Estudo dos níveis de exposição e efeitos à saúde por mercúrio metálico em uma população urbana de Poconé, Mato Grosso, Brasil

    Microsoft Academic Search

    Volney de M. Câmara; Alexandre P. Silva; Fátima Pivetta; Maurício A. Perez; Maria Imaculada M. Lima; Maria Izabel de F. Filhote; Lidia Maria B. Tavares; Marcos V. Maciel; F. V. Alheira; T. Dantas; M. S. Martins

    1996-01-01

    Resumo Foram avaliados os níveis de exposição e dos efeitos causados por emissões na atmosfe- ra de mercúrio metálico proveniente de casas compradoras de ouro na população do Município de Poconé, Estado de Mato Grosso. O projeto foi desenvolvido através da comparação da morbi- dade referida, dos exames clínicos e da análise dos teores de mercúrio na urina de três

  3. The 2003 Superoutburst of an SU UMa-type Dwarf Nova, GO Comae Berenices

    E-print Network

    Akira Imada; Taichi Kato; Makoto Uemura; Ryoko Ishioka; Thomas Krajci; Yasuo Sano; Tonny Vanmunster; Donn R. Starkey; Lewis M. Cook; Jochen Pietz; Daisaku Nogami; Bill Yeung; Kazuhiro Nakajima; Kenji Tanabe; Mitsuo Koizumi; Hiroki Taguchi; Norimi Yamada; Yuichi Nishi; Brian Martin; Ken'ichi Torii; Kenzo Kinugasa; Christopher P. Jones

    2004-12-17

    We photometrically observed the 2003 June superoutburst of GO Gom. The mean superhump period was 0.063059(13) d. The resultant data revealed that (1) the obtained light curve contained a precursor, (2) a plateau stage of the object lasted 8 days, which is remarkably shorter than that of ordinary SU UMa-type dwarf novae, and (3) the amplitude of the superoutburst was less than 5 mag, which is unpredictably small when taking into account the fact that the supercycle of GO Com is about 2800 days. In order to explain these anomalies, a mass elimination process from the accretion disk, such as evaporation, may play an important role.

  4. Infrared photometry of the RS CVn short-period systems - XY UMa and WY Cnc

    SciTech Connect

    Arevalo, M.J.; Lazaro, C. (Instituto de Astrofisica de Canarias, La Laguna (Spain))

    1990-03-01

    Infrared J and K light curves of two RS CVn short-period systems, XY UMa and WY Cnc, are presented. Both systems show similar variability in the infrared to that observed in the visual. From the colors an infrared excess is inferred for the primary component of both systems. A new determination of their geometrical elements is presented and the resulting parameters are compared to those previously obtained from visible photometry. The light curves show peculiarities that may indicate the presence of gas streams in the systems. 27 refs.

  5. EM International, July 1994, Volume 2

    SciTech Connect

    Not Available

    1994-10-01

    The Office of Environmental Management (EM) at the Department of Energy (DOE) is seeking out and leveraging foreign technology, data, and resources in keeping with EM`s mandate to protect public health and the environment through the safe and cost-effective remediation of the Department`s nuclear weapons sites. EM works closely with foreign governments, industry, and universities to obtain innovative environmental technologies, scientific and engineering expertise, and operations experience that will support EM`s objectives. Where appropriate, these international resources are used to manage the more urgent risks at our sites, secure a safe workplace, help build consensus on critical issues, and strengthen our technology development program. Through international agreements EM engages in cooperative exchange of information, technology, and individuals. Currently, we are managing agreements with a dozen countries in Europe, Latin America, and Asia. These agreements focus on environmental restoration, waste management, transportation of radioactive wastes, and decontamination and decommissioning. This publication contains the following articles: in situ remediation integrated program; in-situ characterization and inspection of tanks; multimedia environmental pollutant assessment system (MEPAS); LLNL wet oxidation -- AEA technology. Besides these articles, this publication covers: EU activities with Russia; technology transfer activities; and international organization activities.

  6. Long-term Photometric Analysis of the Active W UMa-type System TU Bootis

    E-print Network

    Coughlin, Jeffrey L; Williamon, Richard M

    2008-01-01

    We present multi-color light curves for the W UMa-type eclipsing binary TU Boo for two epochs separated by 22 years. An analysis of the O-C diagram indicates the earlier observations took place right in the middle of a major period change, thus allowing for a unique study on mass transfer and period changes in this W UMa-type system. We compute model fits to our light curves, along with the only other published set, using the Wilson-Devinney program, and find temporally correlated changes in the size of the secondary component with anomalies in the O-C diagram. We investigate the cause of these changes and find support for the existence of rapid, large-scale mass transfer between the components. We postulate that this interaction allows them to maintain nearly equal surface temperatures despite having achieved only marginal contact. We also find support for the evolutionary scenario in which TU Boo has undergone a mass ratio reversal in the past due to large-scale mass transfer so that what is presently the s...

  7. Long-term Photometric Analysis of the Active W UMa-type System TU Bootis

    E-print Network

    Jeffrey L. Coughlin; Horace A. Dale III; Richard M. Williamon

    2008-07-09

    We present multi-color light curves for the W UMa-type eclipsing binary TU Boo for two epochs separated by 22 years. An analysis of the O-C diagram indicates the earlier observations took place right in the middle of a major period change, thus allowing for a unique study on mass transfer and period changes in this W UMa-type system. We compute model fits to our light curves, along with the only other published set, using the Wilson-Devinney program, and find temporally correlated changes in the size of the secondary component with anomalies in the O-C diagram. We investigate the cause of these changes and find support for the existence of rapid, large-scale mass transfer between the components. We postulate that this interaction allows them to maintain nearly equal surface temperatures despite having achieved only marginal contact. We also find support for the evolutionary scenario in which TU Boo has undergone a mass ratio reversal in the past due to large-scale mass transfer so that what is presently the secondary component of TU Boo is in an advanced evolutionary state, oversized due to a helium-enriched core, with a total system age of $\\geq$ 10 Gyr.

  8. LONG-TERM PHOTOMETRIC ANALYSIS OF THE ACTIVE W UMa-TYPE SYSTEM TU BOOTIS

    SciTech Connect

    Coughlin, Jeffrey L. [Department of Astronomy, New Mexico State University, P.O. Box 30001, MSC 4500, Las Cruces, NM 88003-8001 (United States); Dale, Horace A. III; Williamon, Richard M., E-mail: jlcough@nmsu.edu [Department of Physics, Emory University, Atlanta, GA 30322 (United States)

    2008-09-15

    We present multicolor light curves for the W UMa-type eclipsing binary TU Boo for two epochs separated by 22 years. An analysis of the O - C diagram indicates the earlier observations took place right in the middle of a major period change, thus allowing for a unique study on mass transfer and period changes in this W UMa-type system. We compute model fits to our light curves, along with the only other published set, using the Wilson-Devinney program, and find temporally correlated changes in the size of the secondary component with anomalies in the O - C diagram. We investigate the cause of these changes and find support for the existence of rapid, large-scale mass transfer between the components. We postulate that this interaction allows them to maintain nearly equal surface temperatures despite having achieved only marginal contact. We also find support for the evolutionary scenario in which TU Boo has undergone a mass ratio reversal in the past, due to large-scale mass transfer so that what is presently the secondary component of TU Boo is in an advanced evolutionary state, oversized due to a helium-enriched core, with a total system age of {>=}10 Gyr.

  9. EM Algorithms from a Non-Stochastic Perspective Charles Byrne

    E-print Network

    Byrne, Charles

    EM Algorithms from a Non-Stochastic Perspective Charles Byrne August 27, 2013 Abstract The EM for estimat- ing parameters in statistics, the essence of the EM algorithm is not stochastic. The conventional formulation of the EM algorithm given in many texts and papers on the subject is inadequate. A new formulation

  10. EM Algorithms Charles Byrne (Charles Byrne@uml.edu)

    E-print Network

    Byrne, Charles

    EM Algorithms Charles Byrne (Charles Byrne@uml.edu) Department of Mathematical Sciences University of Massachusetts Lowell Lowell, MA 01854, USA March 6, 2011 Abstract The EM algorithm is not a single algorithm algorithm based on the EM framework we refer to as an "EM algorithm". Because there is no inclusive theory

  11. On the Geometry of EM algorithms David R. Hunter

    E-print Network

    Hunter, David

    of the parameter. Key Words: EM algorithm, MM algorithm 1 Introduction The term "EM algorithm" has been aroundOn the Geometry of EM algorithms David R. Hunter Technical report no. 0303 Department of Statistics that underlies all EM algorithms gives an appreciation for certain aspects of their behavior. Using several

  12. EMS offshore. A new horizon for paramedics.

    PubMed

    Mallard, A S

    1991-10-01

    The difficulty in getting medical aid to offshore drilling platforms can be a source of life-threatening delays. Recently, some companies have charted new waters by actually stationing EMS crews on their rigs. PMID:10116023

  13. The EM Side-Channel(s)

    Microsoft Academic Search

    Dakshi Agrawal; Bruce Archambeault; Josyula R. Rao; Pankaj Rohatgi

    2002-01-01

    We present results of a systematic investigation of leakage of compromising information via electromagnetic (EM) emanations\\u000a from CMOS devices. These emanations are shown to consist of a multiplicity of signals, each leaking somewhat different information\\u000a about the underlying computation. We show that not only can EM emanations be used to attack cryptographic devices where the\\u000a power side-channel is unavailable, they

  14. UMA A NÁLISE DA HISTÓRIA DA E LETRICIDADE PRESENTE E M L IVROS DIDÁTICOS: O C ASO DE BENJAMIN FRANKLIN

    Microsoft Academic Search

    Cibelle Celestino Silva; São Carlos SP

    Este trabalho analisa como a história da eletricidade é apresenta- da em livros didáticos e paradidáticos voltados para os Ensinos Fundamental e Médio. Em particular, analisamos como as contri- buições de Benjamin Franklin são abordadas do ponto de vista da qualidade das informações históricas e das idéias sobre a nature- za da ciência induzidas por estas narrativas. A História da

  15. ANO XLIII N. 109 24/07/2013 ESTE BOLETIM DE SERVIO CONSTITUDO DE 31 (TRINTA E UMA) PGINAS

    E-print Network

    Souza, Max O.

    .012252/2012-34 INSTRUMENTO: Contrato Administrativo nº 024/2012-MC PARTÍCIPES: Petróleo Brasileiro S.A. ­ PETROBRAS e Excelência em SMES da PETROBRAS, em conformidade com os termos e condições nele estipulados e no Anexo nº 3, Gerente Executivo Gás e Energia Corporativo - PETROBRAS. Publique ­ se LEILA MARIA PEREIRA Chefe da Seção

  16. EM results from the simulation EM results on a real data Gibbs results from the simulation Alternative sampling of the DEM Reconstructing stellar DEM and metallicity

    E-print Network

    Wolfe, Patrick J.

    EM results from the simulation EM results on a real data Gibbs results from the simulation, 2010 #12;EM results from the simulation EM results on a real data Gibbs results from the simulation are and µ. #12;EM results from the simulation EM results on a real data Gibbs results from the simulation

  17. Mapping of surface activity on the W UMa-type system VW Cephei

    NASA Technical Reports Server (NTRS)

    Bradstreet, David H.; Guinan, Edward F.

    1988-01-01

    After multifilter photometry of the W UMa-type contact binary VW Cep (P = 6.67 hr; G5V + K0V) in 1986/87 revealed large asymmetries in the light curves believed to be caused by large, cool starspot regions on the surface of the larger stars, in Apr. 1987 it was observed with IUE to study the chromospheres and transition regions of the components. During one complete orbital cycle, three SWP and four LWP low dispersion spectra were obtained, including and then excluding the suspected active region. Phase dependent TR line emission strengths were found, most notably C IV, which is 50 percent stronger when the spot region is most visible. The results could be important because VW Cep represents an extreme case for studying stellar dynamo theory and observations can play a crucial role in the unterstanding of magnetic fields and activity cycles in rapidly rotating solar-like stars.

  18. Ultra-weak magnetic fields in Am stars: ? UMa and ? Leo

    NASA Astrophysics Data System (ADS)

    Blazère, A.; Petit, P.; Lignières, F.; Aurière, M.; Böhm, T.; Wade, G.

    2014-12-01

    An extremely weak circularly-polarized signature was recently discovered in spectral lines of the chemically peculiar Am star Sirius A (Petit et al. 2011). This signal was interpreted as a Zeeman signature related to a sub-gauss longitudinal magnetic field, constituting the first detection of a surface magnetic field in an Am star. We present here ultra-deep spectropolarimetric observations of two other bright Am stars, ? UMa and ? Leo, observed with the NARVAL spectropolarimeter. The line profiles of the two stars display circularly-polarized signatures similar in shape to the observations gathered for Sirius A. These new detections suggest that very weak magnetic fields may be present in the photospheres of a significant fraction of intermediate-mass stars, although the strongly asymmetric Zeeman signatures measured so far in Am stars (featuring a prominent positive lobe and no detected negative lobe) are not expected in the standard theory of the Zeeman effect.

  19. Sonification of Kepler Field SU UMa Cataclysmic Variable Stars V344 Lyr and V1504 Cyg

    NASA Technical Reports Server (NTRS)

    Tutchton, Roxanne M.; Wood, Matt A.; Still, Martin D.; Howell, Steve B.; Cannizzo, John K.; Smale, Alan P.

    2012-01-01

    Sonification is the conversion of quantitative data into sound. In this work we explain the methods used in the sonification of light curves provided by the Kepler instrument from Q2 through Q6 for the cataclysmic variable systems V344 Lyr and V1504 Cyg . Both systems are SU UMa stars showing dwarf nova outbursts and superoutbursts as well as positive and negative superhumps. Focused sonifications were done from average pulse shapes of each superhump, and separate sonifications of the full, residual light curves were done for both stars. The audio of these data reflected distinct patterns within the evolutions of supercycles and superhumps that matched pervious observations and proved to be effective aids in data analysis.

  20. REGIMENTO DO MESTRADO PROFISSIONAL EM AGROECOSSISTEMAS1 REGIMENTO DO CURSO DE MESTRADO PROFISSIONAL EM AGROECOSSISTEMAS

    E-print Network

    Floeter, Sergio Ricardo

    1 REGIMENTO DO MESTRADO PROFISSIONAL EM AGROECOSSISTEMAS1 REGIMENTO DO CURSO DE MESTRADO Curso de Mestrado Profissional conduz ao grau de Mestre Profissional em Agroecossistemas. Art. 2º Curso e constam de resolução desse órgão. Sendo dinâmicas, áreas de concentração e linhas de pesquisa

  1. REGIMENTO DO CURSO DE PS-GRADUAO EM ENGENHARIA E TECNOLOGIA ESPACIAIS, REA DE CONCENTRAO EM

    E-print Network

    REGIMENTO DO CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS, ÁREA DE CONCENTRAÇÂO EM COMBUSTÃO E PROPULSÃO TÍTULO IV DO CORPO DOCENTE Art. 7o ­ O Corpo Docente do Curso é constituído por. Parágrafo 1o ­ Poderão fazer parte do Corpo Docente do Curso, como professores colaboradores, docentes de

  2. Charge, from EM fields only

    E-print Network

    R. L. Collins

    2007-03-04

    Consider the electric field E about an electron. Its source has been thought a substance called charge, enclosed within a small volume that defines the size of the electron. Scattering experiments find no size at all. Charge is useful, but mysterious. This study concludes that charge is not real. Useful, but not real. Absent real charge, the electric field must look to a different source. We know another electric field, vxB, not sourced by charge. A simple model of the electron, using EM fields only, has been found that generates an electric field vxB very like E. Gauss' law finds the model contains charge, but div vxB cannot find the charge density. The model contains a permanent magnetic flux quantum, configured as a dipole. The dipolar B fields spin around the symmetry axis, accounting for angular momentum. Spin stabilizes the magnetic flux quantum, and creates the vxB electric field. Stability in this model is dynamic. Energy is exchanged between the dipolar magnetic moment and an encircling toroidal displacement current, at the Compton frequency, mc^2/h = 1.24x10^20 Hz. The electric field undulates at this rate, instead of being static like E associated with charge. Absent any real charge, we have to abandon the notion that size of a charged particle is that of a small sack full of charge. The only electric field is vxB, and its source is not charge. What is the size of an electron? Coulomb scattering finds it point-like, but its spinning B fields extend to infinity.

  3. EMS adaptation for climate change

    NASA Astrophysics Data System (ADS)

    Pan, C.; Chang, Y.; Wen, J.; Tsai, M.

    2010-12-01

    The purpose of this study was to find an appropriate scenario of pre-hospital transportation of an emergency medical service (EMS) system for burdensome casualties resulting from extreme climate events. A case of natural catastrophic events in Taiwan, 88 wind-caused disasters, was reviewed and analyzed. A sequential-conveyance method was designed to shorten the casualty transportation time and to promote the efficiency of ambulance services. A proposed mobile emergency medical center was first constructed in a safe area, but nearby the disaster area. The Center consists of professional medical personnel who process the triage of incoming patients and take care of casualties with minor injuries. Ambulances in the Center were ready to sequentially convey the casualties with severer conditions to an assigned hospital that is distant from the disaster area for further treatment. The study suggests that if we could construct a spacious and well-equipped mobile emergency medical center, only a small portion of casualties would need to be transferred to distant hospitals. This would reduce the over-crowding problem in hospital ERs. First-line ambulances only reciprocated between the mobile emergency medical center and the disaster area, saving time and shortening the working distances. Second-line ambulances were highly regulated between the mobile emergency medical center and requested hospitals. The ambulance service of the sequential-conveyance method was found to be more efficient than the conventional method and was concluded to be more profitable and reasonable on paper in adapting to climate change. Therefore, additional practical work should be launched to collect more precise quantitative data.

  4. Survey of Period Variations of Superhumps in SU UMa-Type Dwarf Novae. IV. The Fourth Year (2011-2012)

    NASA Astrophysics Data System (ADS)

    Kato, Taichi; Hambsch, Franz-Josef; Maehara, Hiroyuki; Masi, Gianluca; Miller, Ian; Noguchi, Ryo; Akasaka, Chihiro; Aoki, Tomoya; Kobayashi, Hiroshi; Matsumoto, Katsura; Nakagawa, Shinichi; Nakazato, Takuma; Nomoto, Takashi; Ogura, Kazuyuki; Ono, Rikako; Taniuchi, Keisuke; Stein, William; Henden, Arne; de Miguel, Enrique Kiyota, Seiichiro; Dubovsky, Pavol A.; Kudzej, Igor; Imamura, Kazuyoshi; Akazawa, Hidehiko; Takagi, Ryosuke; Wakabayashi, Yuya; Ogi, Minako; Tanabe, Kenji; Ulowetz, Joseph; Morelle, Etienne; Pickard, Roger D.; Ohshima, Tomohito; Kasai, Kiyoshi; Pavlenko, Elena P.; Antonyuk, Oksana I.; Baklanov, Aleksei V.; Antonyuk, Kirill; Samsonov, Denis; Pit, Nikolaj; Sosnovskij, Aleksei; Littlefield, Colin; Sabo, Richard; Ruiz, Javier; Krajci, Thomas; Dvorak, Shawn; Oksanen, Arto; Hirosawa, Kenji; Goff, William N.; Monard, Berto; Shears, Jeremy; Boyd, David; Voloshina, Irina B.; Shugarov, Sergey Yu.; Chochol, Drahomir; Miyashita, Atsushi; Pietz, Jochen; Katysheva, Natalia; Itoh, Hiroshi; Bolt, Greg; Andreev, Maksim V.; Parakhin, Nikolai; Malanushenko, Viktor; Martinelli, Fabio; Denisenko, Denis; Stockdale, Chris; Starr, Peter; Simonsen, Mike; Tristram, Paul J.; Fukui, Akihiko; Tordai, Tamas; Fidrich, Robert; Paxson, Kevin B.; Itagaki, Koh-ichi; Nakashima, Youichirou; Yoshida, Seiichi; Nishimura, Hideo; Kryachko, Timur V.; Samokhvalov, Andrey V.; Korotkiy, Stanislav A.; Satovski, Boris L.; Stubbings, Rod; Poyner, Gary; Muyllaert, Eddy; Gerke, Vladimir; MacDonald, Walter, II; Linnolt, Michael; Maeda, Yutaka; Hautecler, Hubert

    2013-02-01

    Continuing the project described by Kato et al. (2009, PASJ, 61, S395), we collected times of superhump maxima for 86 SU UMa-type dwarf novae, mainly observed during the 2011-2012 season. We confirmed general trends recorded in our previous studies, such as the relation between period derivatives and orbital periods. There are some systems showing positive period derivatives despite the long orbital period. We observed the 2011 outburst of the WZ Sge-type dwarf nova BW Scl, and recorded an O - C diagram similar to those of previously known WZ Sge-type dwarf novae. The WZ Sge-type dwarf nova OT J184228.1+483742 showed an unusual pattern of double outbursts composed of an outburst with early superhumps and one with ordinary superhumps. We propose an interpretation that a very small growth rate of the 3:1 resonance due to an extremely low mass-ratio led to quenching the superoutburst before the ordinary superhump appeared. We systematically studied ER UMa-type dwarf novae, and found that V1159 Ori showed positive superhumps similar to ER UMa in the 1990s. The recently recognized ER UMa-type object BK Lyn dominantly showed negative superhumps, and its behavior was very similar to the present-day state of ER UMa. The pattern of period variations in AM CVn-type objects was very similar to that of short-period hydrogen-rich SU UMa-type dwarf novae, making them a helium analogue of hydrogen-rich SU UMa-type dwarf novae. SBS 1108+574, a peculiar hydrogen-rich dwarf nova below the period minimum, showed a very similar pattern of period variations to those of short-period SU UMa-type dwarf novae. The mass-ratio derived from the detected orbital period suggests that this secondary is a somewhat evolved star whose hydrogen envelope was mostly stripped during the mass-exchange. CC Scl, MASTER OT J072948.66+593824.4, and OT J173516.9+154708 showed only low-amplitude superhumps with complex profiles. These superhumps are likely to be a combination of two closely separated periods.

  5. Filter banks and the EM algorithm

    SciTech Connect

    Mair, B.A.; Carroll, R.B.; Anderson, J.M.M. [Univ. of Florida, Gainesville, FL (United States)

    1996-12-31

    In this paper, we present a wavelet based modification of the ML-EM algorithm for reconstructing positron emission tomography images. By using the filter bank implementation of the wavelet transform, this algorithm has the flexibility to incorporate a priori information, while maintaining the same computational complexity as the standard ML-EM algorithm. Thus, it has a significant computational advantage over usual Bayesian methods. It differs from recent wavelet-based Bayesian methods as it achieves {open_quotes}regularization{close_quotes} by an adaptive, wavelet-based method of thresholding which minimizes Stein`s Unbiased Estimate of Risk. The basic method consists of applying Donoho and Johnstone`s SureShrink wavelet denoising of the Poisson data, and then applying the standard ML-EM algorithm to the denoised data. A more elaborate method is discussed in which a wavelet denoising step is inserted after each EM iteration. This technique differs from previous smoothing techniques applied to the ML-EM algorithm since it is able to recover edges in discontinuous images.

  6. ISSN 0103-9741 Monografias em Cincia da Computao

    E-print Network

    Endler, Markus

    uma nova estrat´egia para traders baseada na informac¸ ~ao do VWAP. Nesta estrat´egia uma compra ´e interday para alertar um dia candidato de compra/venda e um detector intraday para alertar, dentro do dia candidato, um instante candidato de compra/venda. Para o detector interday, utilizamos um preditor SVM para

  7. Plume Created From a Collapse of the Upper Portion of the Halema'uma'u Vent Cavity

    USGS Multimedia Gallery

    With lava retreating deeper into the Halema'uma'u vent cavity over the past two days, the cavity walls have experienced more frequent collapses. At 2:23pm today (March 7), a collapse from the upper portion of the vent cavity produced a robust brown plume, but did not eject any large particles....

  8. O peso relativo dos setores econômicos na formação do valor adicionado- uma análise à luz da teoria marxiiana

    Microsoft Academic Search

    Águida Cristina Santos Almeida

    Esta dissertação tem por objetivo investigar a importância dos setores econômicos na formação do valor adicionado. Parte de uma análise crítica das estatísticas das contas nacionais, de responsabilidade do IBGE, discutindo a metodologia dos cálculos e a teoria econômica que lhe serve de base e que fundamenta a afirmação de que o setor de serviços vem cada vez mais se

  9. Externally triggered renewed bubble nucleation in basaltic magma: The 12 October 2008 eruption at Halema`uma`u

    E-print Network

    Manga, Michael

    at Halema`uma`u Overlook vent, Klauea, Hawai`i, USA Rebecca J. Carey,1 Michael Manga,2 Wim Degruyter,2 external to the degassing system. Citation: Carey, R. J., M. Manga, W. Degruyter, D. Swanson, B. Houghton and relatively slow outgassing promote energetic and explosive eruption [Namiki and Manga, 2008]. [3] Degassing

  10. AÇÃO EXTENSIONISTA DA EMPAER FRENTE À NOVA PNATER: UMA ANÁLISE A PARTIR DO ASSENTAMENTO GUAPIRAMA, CAMPO NOVO DO PARECIS - MT

    Microsoft Academic Search

    Gilmar Laforga; Andreia De Oliveira Vieira

    2008-01-01

    O modelo de agricultura ainda praticado continua a causar impactos negativos como a perda de solo, erosão genética, contaminação do solo e da água entre muitos outros efeitos. Considerando-se esse cenário e assim buscar minimizar estes processos, foi criada a Política Nacional de Assistência Técnica e Extensão Rural – PNATER, que orienta uma extensão rural baseada nos princípios epistemológico da

  11. Risk Communication Within the EM Program

    SciTech Connect

    Edelson, M.

    2003-02-26

    The U.S. Department of Energy Environmental Management program (EM) conducts the most extensive environmental remediation effort in the world. The annual EM budgets have exceeded $6,000,000,000 for approximately ten years and EM has assumed responsibility for the cleanup of the largest DOE reservations (i.e., at Hanford, Washington, Aiken, South Carolina, and Idaho Falls, Idaho) as well as the facilities at Rocky Flats, Colorado and in Ohio. Each of these sites has areas of extensive radioactive and chemical contamination, numerous surplus facilities that require decontamination and removal, while some have special nuclear material that requires secure storage. The EM program has been criticized for being ineffective (1) and has been repeatedly reorganized to address perceived shortcomings. The most recent reorganization was announced in 2001 to become effective at the beginning of the 2003 Federal Fiscal Year (i.e., October 2002). It was preceded by a ''top to bottom'' review (TTBR) of the program (2) that identified several deficiencies that were to be corrected as a result of the reorganization. One prominent outcome of the TTBR was the identification of ''risk reduction'' as an organizing principle to prioritize the activities of the new EM program. The new program also sought to accelerate progress by identifying a set of critical activities at each site that could be accelerated and result in more rapid site closure, with attendant risk, cost, and schedule benefits. This paper investigates how the new emphasis on risk reduction in the EM program has been communicated to EM stakeholders and regulators. It focuses on the Rocky Flats Environmental Technology Site (RFETS) as a case study and finds that there is little evidence for a new emphasis on risk reduction in EM communications with RFETS stakeholders. Discussions between DOE and RFETS stakeholders often refer to ''risk,'' but the word serves as a placeholder for other concepts. Thus ''risk'' communication at RFETS is lively and involves important issues, but often does not inform participants about true ''risk reduction.''

  12. Simplex EMS users knock company's service support

    SciTech Connect

    Cohn, L.

    1982-06-14

    Simplex Tape Recorder Co. is not responding fast enough to please some of its energy management system (EMS) users who need service or new parts. The users complain that Simplex load-shedding, time-of-day control, and duty-cycling functions do not compare with the quality of its security and fire functions. Company spokesmen claim that service and parts are available on a 24-hour basis from technically-trained personnel. The company has sold time clocks since 1959, and marketed microprocessor-based EMS equipment since 1980. Users and service managers disagree over reported delays. (DCK)

  13. On Convergence Properties of the EM Algorithm for Gaussian Mixtures

    E-print Network

    Jordan, Michael

    1995-04-21

    "Expectation-Maximization'' (EM) algorithm and gradient-based approaches for maximum likelihood learning of finite Gaussian mixtures. We show that the EM step in parameter space is obtained from the gradient via a ...

  14. CURSO DE PS-GRADUAO EM COMPUTAO APLICADA

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM COMPUTAÇÃO APLICADA Coordenador Acadêmico Reinaldo Roberto Rosa, Dr, participação em todos os WORCAPs (Workshop dos Cursos de Mestrado e Doutorado da CAP) e, obrigatoriedade de

  15. EM-ONE : an architecture for reflective commonsense thinking

    E-print Network

    Singh, Pushpinder, 1972-2006.

    2005-01-01

    This thesis describes EM-ONE, an architecture for commonsense thinking capable of reflective reasoning about situations involving physical, social, and mental dimensions. EM-ONE uses as its knowledge base a library of ...

  16. DEZ ANOS DE EXPERIÊNCIA DO COMITÊ DE ÉTICA EM PESQUISA DA SECRETARIA DE SAÚDE DO DISTRITO FEDERAL, BRASIL

    PubMed Central

    Novaes, Maria Rita C. G.; Guilhem, Dirce; Lolas, Fernando

    2009-01-01

    O objetivo deste artigo é relatar a experiência do Comitê de Ética em Pesquisa da Secretaria de Estado de Saúde do Distrito Federal (CEP/SES/DF) Brasil, durante o período de 10 anos a partir de sua fundação. Trata-se de uma avaliação descritiva e documental, na modalidade estudo de caso, utilizando-se a totalidade de projetos protocolados no CEP/SES/DF (N° 052/08) nesse período. As pendências mais freqüentes dos projetos foram: termo de consentimento livre e esclarecido (30%), folha de rosto (25%), metodologia (20%), curriculum vitae (12%), planilha de orçamento (9%), outros (4%). O relato das atividades do CEP/SES/DF no período de 10 anos revelou, através de sua produtividade, a legitimidade do processo de análise ética dos protocolos visando à proteção dos participantes da pesquisa. PMID:19888441

  17. Spectroscopic Analyses of the Planetary System Candidates: 55 Cnc, 51 Peg, 47 UMa, 70 Vir, and HD 114762

    E-print Network

    Guillermo Gonzalez

    1996-09-20

    The stars 55 Cnc, 51 Peg, 47 UMa, 70 Vir, and HD 114762 have recently been proposed to harbor planetary mass companions. Using spectrospic methods we find that 55 Cnc and 51 Peg are super metal- rich, 47 UMa and 70 Vir have roughly solar metallicities, and HD 114762 is metal-poor. Otherwise, the abundance patterns, expressed as [X/Fe], are approximately solar. The ages of 47 UMa and 51 Peg are similar to that of the Sun; 70 Vir is slightly older, and 55 Cnc and HD 114762 are at least 10 Gyr old. Our estimates of vsini for the parent stars are 1.4, 1.8, 2.0, Cnc, 51 Peg, 47 UMa, 70 Vir, and HD 114762, respectively. Using these data and estimates for the rotation periods and radii, the corresponding masses of the companions are: > 0.6, 0.51, 4.6, > 20, and > 8.5 MJ. The systems appear to fall into three groups: roughly Jupiter mass companions with small circular orbits with metal-rich parent stars (55 Cnc and 51 Peg), larger companions with larger circular orbits (47 UMa), and much more massive companions with large eccentric orbits around moderately metal- poor parent stars (70 Vir and HD 114762). Our findings are consistent with the recently proposed mechanism whereby a gas giant migrates to within a few hundredths of an AU of its parent star during the formative epoch of the planetary system. During this process the material between the giant planet and the star is accreted onto the latter. If the accreted material is depleted in H and He, then the photospheric composition of the parent star might be altered significantly.

  18. UNIVERSIDADE DE BRASLIA CENTRO DE EXCELNCIA EM TURISMO -CET

    E-print Network

    Maier, Rudolf Richard

    UNIVERSIDADE DE BRASÍLIA CENTRO DE EXCEL�NCIA EM TURISMO - CET PROGRAMA DE P�S-GRADUA��O EM TURISMO EDITAL No. 01/2013 UNIVERSIDADE DE BRASÍLIA PROGRAMA DE P�S-GRADUA��O EM TURISMO EDITAL No. 01/2013 SELE��O DE CANDIDATOS �S VAGAS DO PROGRAMA DE P�S- GRADUA��O EM TURISMO PARA OS CURSOS DE MESTRADO

  19. UNIVERSIDADE DE BRASLIA CENTRO DE EXCELNCIA EM TURISMO -CET

    E-print Network

    Maier, Rudolf Richard

    UNIVERSIDADE DE BRASÍLIA CENTRO DE EXCEL�NCIA EM TURISMO - CET PROGRAMA DE P�S-GRADUA��O EM TURISMO EDITAL No. 04/2013 1 UNIVERSIDADE DE BRASÍLIA PROGRAMA DE P�S-GRADUA��O EM TURISMO EDITAL No. 04/2012 SELE��O DE CANDIDATOS �S VAGAS DO PROGRAMA DE P�S-GRADUA��O EM TURISMO PARA OS CURSOS DE MESTRADO

  20. An Extensive Analysis of the Triple W UMa Type Binary FI Boo

    NASA Astrophysics Data System (ADS)

    Christopoulou, P.-E.; Papageorgiou, A.

    2013-12-01

    We present a detailed analysis of the interesting W UMa binary FI Boo in view of the spectroscopic signature of a third body through photometry, period variation, and a thorough investigation of solution uniqueness. We obtained new BVRcIc photometric data that, when combined with spectroscopic data, enable us to analyze the system FI Boo and determine its basic orbital and physical properties through PHOEBE, as well as the period variation by studying the times of the minima. This combined approach allows us to study the long-term period changes in the system for the first time in order to investigate the presence of a third body and to check extensively the solution uniqueness and the uncertainties of derived parameters. Our modeling indicates that FI Boo is a W-type moderate (f = 50.15% ± 8.10%) overcontact binary with component masses of M h = 0.40 ± 0.05 M ? and M c = 1.07 ± 0.05 M ?, temperatures of T h = 5746 ± 33 K and T c = 5420 ± 56 K, and a third body, which may play an important role in the formation and evolution. The results were tested by heuristic scanning and parameter kicking to provide the consistent and reliable set of parameters that was used to obtain the initial masses of the progenitors (1.71 ± 0.10 M ? and 0.63 ± 0.01 M ?, respectively). We also investigated the evolutionary status of massive components with several sets of widely used isochrones.

  1. Precursor outbursts and superoutbursts in the SU UMa-type dwarf nova NN Camelopardalis

    NASA Astrophysics Data System (ADS)

    Shears, J.; Foote, J.; Mack Julian, W.; Krajci, T.; Kudzej, I.; Miller, I.; Morelle, E.; Sabo, R.; Solovieva, I.; Staels, B.; Vanmunster, T.

    2011-12-01

    We report photometry of three outbursts of NN Cam in 2007, 2008 and 2009. The 2007 event started with a normal outburst, lasting about 4 days, which was a precursor to a superoutburst lasting at least 13 days. Both the precursor and the superoutburst had an amplitude of 4.9 mag above mean quiescence. Superhumps with a maximum peak-to-peak amplitude of 0.22 mag were detected during the superoutburst, with a mean superhump period Psh= 0.07385(56)d. Psh decreased continuously with dPsh/dt= ?1.72(23)x10^-3. We used our measurement to confirm that the shorter of two possible values of Porb reported by another researcher is correct; Porb= 0.0717d. The 2008 outburst was rather poorly observed, although we present evidence that this too may have been a superoutburst. The 2009 event was also a superoutburst, with Psh= 0.07414(44)d, but we could find no evidence for a precursor. From the 2007 and 2009 data, we report a superhump period excess of e= 0.030(8) to 0.034(6), which is typical for SU UMa dwarf novae of similar orbital period, and estimate the binary mass ratio q= Mwd/Msec~ 0.11 to 0.17.

  2. UNIVERSIDADE DE BRASLIA PROGRAMA DE PS-GRADUAO EM ECOLOGIA

    E-print Network

    Lucero, Jorge Carlos

    UNIVERSIDADE DE BRASÍLIA PROGRAMA DE PÓS-GRADUAÇÃO EM ECOLOGIA EDITAL No. 01/2012 SELEÇÃO DE CANDIDATOS ÀS VAGAS DO PROGRAMA DE PÓS-GRADUAÇÃO EM ECOLOGIA PARA O CURSO DE DOUTORADO PARA O SEGUNDO PERÍODO LETIVO DE 2012 1. PREÂMBULO 1.1 A Coordenadora do Programa de Pós-Graduação em ECOLOGIA, no uso de suas

  3. Pesquisa em Memria ltima alterao: 10 de Outubro de 2006

    E-print Network

    Chaimowicz, Luiz

    Pesquisa em Memória Secundária Última alteração: 10 de Outubro de 2006 Transparências elaboradas, Leonardo Mata #12;Projeto de Algoritmos ­ Cap.1 Introdução 1 Introdução · Pesquisa em memória secundária transferências). · Memórias secundárias: apenas um registro pode ser acessado em um dado momento (acesso

  4. 7 CFR 1945.35 - Special EM loan training.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...2012-01-01 2012-01-01 false Special EM loan training. 1945.35 Section 1945...Assistance-General § 1945.35 Special EM loan training. (a) General...completed they will be well qualified to process EM loans without undue delay. The...

  5. Online EM Algorithm for Hidden Markov Models Olivier Cappe

    E-print Network

    Online EM Algorithm for Hidden Markov Models Olivier Capp´e LTCI, TELECOM ParisTech & CNRS Abstract recursive) version of the Expectation-Maximization (EM) algorithm. It is first shown that under suitable mixing assumptions, the large sample behavior of the traditional (batch) EM algorithm may be analyzed

  6. 7 CFR 759.6 - EM to be made available.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2014-01-01 2014-01-01 false EM to be made available. 759.6 Section 759...DESIGNATIONS AND NOTIFICATIONS § 759.6 EM to be made available. (a) For purposes of the EM Program under part 764, subpart I, of...

  7. On Convergence Properties of the EM Algorithm for Gaussian Mixtures

    Microsoft Academic Search

    Lei Xu; Michael I. Jordan

    1996-01-01

    We build up the mathematical connection between the Expectation-Maximization (EM) algorithm and gradient-based approaches for maximum likelihood learning of finite gaussian mixtures. We show that the EM step in parameter space is obtained from the gradient via a projection matrix P, and we provide an explicit expression for the matrix. We then analyze the convergence of EM in terms of

  8. COMBINATION OF EM AND DC MEASUREMENTS FOR UPPER CRUSTAL STUDIES

    E-print Network

    Harinarayana, T.

    COMBINATION OF EM AND DC MEASUREMENTS FOR UPPER CRUSTAL STUDIES T. HARINARAYANA National geophysical methods, electrical (E) and electromagnetic (EM) methods also suffer from ambiguity benefit of obtaining more confidence in the derived model, joint use of E and EM methods has added

  9. Em dvida o valor de cortes a devolver s universidades

    E-print Network

    Instituto de Sistemas e Robotica

    Em dúvida o valor de cortes a devolver às universidades Secretário de Estado reuniu-se ontem com o a garantia de que "a muito curto prazo" se- rão entregues os 30 milhões em dívida, revelou ao JN o rei- tor verbas cortadas que são entregues em valores inferiores". "Nos próximos dias, tenho de tomar decisões

  10. EM Effects on Semiconductor Devices, Gates and Integrated Circuit

    E-print Network

    Anlage, Steven

    EM Effects on Semiconductor Devices, Gates and Integrated Circuit Interconnects Dept. of Electrical Xi Shao, Parvez N. Guzdar Akin Akturk, Zeynep Dilli, Bo Yang, Todd Firestone #12;EM Effects Verify with experiments: Chips fabricated through MOSIS #12;Outline EM Coupling: Levels Investigated Task

  11. Galp investe em cincia no Brasil Margarida Davim

    E-print Network

    Instituto de Sistemas e Robotica

    Galp investe em ciência no Brasil Margarida Davim margarida.davim@sol.pt Lei brasileira obriga petrolíferas a investir 1% dos lucros em investigação. Até 2017, Galp deve apoiar projectos no valor de 140 dólares em investiga- ção e projectos científicos no Brasil até 2017. O investimento - cerca de 102

  12. Online EM for Unsupervised Models Percy Liang Dan Klein

    E-print Network

    Pratt, Vaughan

    Online EM for Unsupervised Models Percy Liang Dan Klein Computer Science Division, EECS Department) EM algorithm plays an important role in unsupervised induction, but it some- times suffers from slow find bet- ter solutions than those found by batch EM. We support these findings on four unsuper- vised

  13. Ps-Graduao em Gerenciamento de Sistemas Espaciais Disciplina Isolada

    E-print Network

    Pós-Graduação em Gerenciamento de Sistemas Espaciais Disciplina Isolada Documentos a serem apresentados na secretaria do CSE: comprovante de: matricula do candidato em Curso de Pós-Graduação ou de ser Substituído por Declaração que conste data de colação de grau. Em hipótese alguma será aceito aluno que não

  14. Online EM Algorithm for Hidden Markov Models Olivier Cappe

    E-print Network

    Paris-Sud XI, Université de

    Online EM Algorithm for Hidden Markov Models Olivier Capp´e LTCI, Telecom ParisTech & CNRS Abstract in the Expectation-Maximization (EM) methodology consists in reparameterizing the problem using complete in HMMs based on an auxiliary recursion. Although the proposed online EM algorithm resembles a classical

  15. EM Effects on Semiconductor Devices Gates and Integrated Circuit

    E-print Network

    Anlage, Steven

    EM Effects on Semiconductor Devices Gates and Integrated Circuit Interconnects Dept. of Electrical Xi Shao, Parvez N. Guzdar4 Akin Akturk, Zeynep Dilli, Yun Bai, Todd Firestone #12;EM Effects. Verify with experiments: Chips fabricated through MOSIS #12;Outline EM Coupling: Levels Investigated Task

  16. Parallel EM Learning for Symbolic-Statistical Models

    E-print Network

    Sato, Taisuke

    Parallel EM Learning for Symbolic- Statistical Models Yusuke Izumi Department of Computer Science as previous author) sato@mi.cs.titech.ac.jp keywords: parallel EM algorithm, symbolic-statistical models, PRISM, distributed parallel computing Summary EM learning, i.e. parameter learning for probabilistic

  17. 7 CFR 1945.35 - Special EM loan training.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...2011-01-01 2009-01-01 true Special EM loan training. 1945.35 Section 1945...Assistance-General § 1945.35 Special EM loan training. (a) General...completed they will be well qualified to process EM loans without undue delay. The...

  18. EM DESTAQUE Resgate do Chipre empurra bolsas para o vermelho

    E-print Network

    Instituto de Sistemas e Robotica

    EM DESTAQUE Resgate do Chipre empurra bolsas para o vermelho Resgate da União Europeia ao Chipre: Interessados em inve têm de se preparar - Câmara de co Moçambique: Portugueses que pro de Comércio triplicou em dois anos Outros sites Impresa: SIC TV Mais Escape Olhares J. Letras V. Júnior E. Informática

  19. 7 CFR 759.6 - EM to be made available.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2013-01-01 2013-01-01 false EM to be made available. 759.6 Section 759...DESIGNATIONS AND NOTIFICATIONS § 759.6 EM to be made available. (a) For purposes of the EM Program under part 764, subpart I, of...

  20. 7 CFR 1945.35 - Special EM loan training.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...2010-01-01 2009-01-01 true Special EM loan training. 1945.35 Section 1945...Assistance-General § 1945.35 Special EM loan training. (a) General...completed they will be well qualified to process EM loans without undue delay. The...

  1. Electromagnetic ``Bubbles'' and Shock Waves: Unipolar, Nonoscillating EM Solitons

    Microsoft Academic Search

    A. E. Kaplan; P. L. Shkolnikov

    1995-01-01

    We show that atomic gases can support solitary pulses of a unipolar electromagnetic field (``EM bubbles'') with amplitude up to the atomic field ( ~109 V\\/cm) and duration down to ~ 10-16 s. EM bubbles propagate without dispersion, are stable, and are insensitive to the change of gas density. Atomic gasses can also support an EM shock wave forming a

  2. REGIMENTO DO CURSO DE PSGRADUAO EM COMPUTAO APLICADA

    E-print Network

    REGIMENTO DO CURSO DE PÓSGRADUAÇÃO EM COMPUTAÇÃO APLICADA Regimento aprovado pelo CPG em 19/02/2003. TÍTULO I DOS OBJETIVOS E FINALIDADES Art 1º O Curso de PósGraduação a nível de Mestrado e Doutorado em Computação Aplicada CAP, doravante referido como Curso, objetiva formar e capacitar pessoal de nível

  3. CURSO DE PS-GRADUAO EM ENGENHARIA E TECNOLOGIA ESPACIAIS

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE CONCENTRAÇÃO EM COMBUSTÃO E PROPULSÃO Coordenadora Acadêmica do Curso Evandro Marconi Rocco Coordenador da Área de Concentração David, Doutor, INPE, 2006. #12;CURSO DE ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE CONCENTRAÇÃO EM COMBUSTÃO E

  4. REGIMENTO DO CURSO DE PSGRADUAO EM COMPUTAO APLICADA

    E-print Network

    REGIMENTO DO CURSO DE PÓSGRADUAÇÃO EM COMPUTAÇÃO APLICADA Regimento aprovado pelo CPG em 04/11/2004. TÍTULO I DOS OBJETIVOS E FINALIDADES Art 1º O Curso de PósGraduação a nível de Mestrado e Doutorado em Computação Aplicada CAP, doravante referido como Curso, objetiva formar e capacitar pessoal de nível

  5. Incentives for P2P-Assisted Content Distribution: If You Can't Beat 'Em, Join 'Em

    E-print Network

    Wierman, Adam

    Incentives for P2P-Assisted Content Distribution: If You Can't Beat 'Em, Join 'Em Vinod Ramaswamy distributors to search for methods of defraying costs. One technique that is often suggested for defraying

  6. Novo modelo em 2015 para financiar

    E-print Network

    Instituto de Sistemas e Robotica

    não tem sido cabal- mente aplicada. O que o Governo propõe agora é "criar um modelo de financiamento Governo vai agora discutir com as universidades e politécnicos como pôr a ideia em prática, dos indicadores ao modo como são calculados. "Solicitámos hoje o contributo das instituições. Agora vai começar o

  7. Efficient Scanning for EM Based Target Localization

    E-print Network

    Fua, Pascal

    of the time. 1 Introduction Focused Ion Beam Scanning Electron Microscopes (FIB-SEM) and their ability Image Fig. 1. FIB-SEM Scanning Process. The microscope repeatedly scans the surface of a sample blockEfficient Scanning for EM Based Target Localization Raphael Sznitman, Aurelien Lucchi, Natasa

  8. EM Algorithms for PCA and SPCA

    Microsoft Academic Search

    Sam T. Roweis

    1997-01-01

    Abstract I present an expectation - maximization (EM) algorithm for principal component analysis (PCA) The algorithm allows a few eigenvectors and eigenvalues to be extracted from large collections of high dimensional data It is computationally very efficient in space and time It also natu - rally accommodates missing information I also introduce a new variant of PCA called sensible principal

  9. EM algorithms for ML factor analysis

    Microsoft Academic Search

    Donald B. Rubin; Dorothy T. Thayer

    1982-01-01

    The details of EM algorithms for maximum likelihood factor analysis are presented for both the exploratory and confirmatory models. The algorithm is essentially the same for both cases and involves only simple least squares regression operations; the largest matrix inversion required is for aq ×q symmetric matrix whereq is the matrix of factors. The example that is used demonstrates that

  10. EMS Division Potential Benefits of Selected

    E-print Network

    Validation Program for ONR 300 KW Test Stand Motor 3.7 MW Motor Operated Successfully with SC magnet at full Homopolar Motors & Projections for Ship Propulsion Topics NOTE: Search for the interplay of technical disciplines!!!!! #12;EMS Division Homopolar Motor Outline ·Homopolar Motor Basics ·Homopolar Motor Technology

  11. EM Algorithm for Symmetric Causal Independence Models

    Microsoft Academic Search

    Rasa Jurgelenaite; Tom Heskes

    2006-01-01

    Causal independence modelling is a well-known method both for reducing the size of probability tables and for explaining the underly- ing mechanisms in Bayesian networks. In this paper, we present the EM algorithm to learn the parameters in causal independence models based on the symmetric Boolean function. The developed algorithm enables us to assess the practical usefulness of the symmetric

  12. ESPÉCIES DO GÊNERO Eimeria (APICOMPLEXA: EIMERIIDAE) EM TAMANDUÁS-BANDEIRA (Myrmecophaga tridactyla LINNAEUS, 1758) EM CATIVEIRO

    Microsoft Academic Search

    FAGNER LUIZ DA C. FREITAS; ANDRÉ S. ZANETTI; CÉLIO R. MACHADO; ROSANGELA Z. MACHADO

    1 ABSTRACT:- FREITAS, F.L. DA C.; ALMEIDA, K. DE S.; ZANETTI, A.S.; NASCIMENTO, A.A. DO; MACHADO, C. R.; MACHADO, R.Z. (Species of the genus Eimeria (Apicomplexa: Eimeriidae) in giant anteaters (Myrmecophaga tridactyla Linnaeus, 1758) in captivity). Espécies do gênero Eimeria (Apicomplexa: Eimeriidae) em Tamanduás-bandeira (Myrmecophaga tridactyla Linnaeus, 1758) em cativeiro. Revista Brasileira de Parasitologia Veterinária, v. 15, n. 1, p.

  13. Information geometry of the EM and em algorithms for neural networks

    Microsoft Academic Search

    Shun-ichi Amari

    1995-01-01

    In order to realize an input-output relation given by noise-contaminated examples,it is effective to use a stochastic model of neural networks. A model networkincludes hidden units whose activation values are not specified nor observed. It isuseful to estimate the hidden variables from the observed or specified input-outputdata based on the stochastic model. Two algorithms, the EM - and em-algorithms,have so

  14. Estado atual do tratamento da coronariopatia crônica em pacientes diabéticos: evidências e controvérsias baseadas em ensaios clínicos

    Microsoft Academic Search

    Neuza H. Lopes; Jeane M. Tsutsui; Whady A. Hueb

    2007-01-01

    RESUMO Diabetes mellitus é um dos principais fatores de risco para a doença arterial coronária. A doença progride de forma mais acelerada em pacientes diabéticos e está associada com pior prognóstico. Embora a revascularização miocárdica garanta alívio rápido dos sintomas em pacientes com doença arterial coronária documentada, não existe substancial evidência de benefício prognóstico, salvo em situações anatômicas específicas. Adicionalmente,

  15. REGIMENTO DO CURSO DE PSGRADUAO EM COMPUTAO APLICADA Regimento aprovado pelo CPG em 07/11/2006

    E-print Network

    REGIMENTO DO CURSO DE PÓSGRADUAÇÃO EM COMPUTAÇÃO APLICADA Regimento aprovado pelo CPG em 07/11/2006 TÍTULO I DOS OBJETIVOS E FINALIDADES Art 1º O Curso de pósgraduação em Computação Aplicada, doravante referido como Curso, mantém programas de Mestrado e Doutorado com objetivo de formar e capacitar pessoal

  16. V344 Lyrae: A Touchtone SU UMa Cataclysmic Variable in the Kepler Field

    NASA Technical Reports Server (NTRS)

    Smale, Alan P.; Wood, Matt A.; Still, Martin D.; Howell, Steve B.; Cannizzo, John K.

    2012-01-01

    We report on the analysis of the Kepler short-cadence (SC) light curve of V344 Lyr obtained during 2009 June 20 through 2010 Mar 19 (Q2-Q4). The system is an SU UMa star showing dwarf nova outbursts and superoutbursts, and promises to be a touchstone for CV studies for the foreseeable future. The system displays both positive and negative super humps with periods of 2.20 and 2.06-hr, respectively, and we identify an orbital period of 2.11-hr. The positive super humps have a maximum amplitude of approximately 0.025-mag, the negative super humps a maximum amplitude of approximately 0.8 mag, and the orbital period at quiescence has an amplitude of approximately 0.025 mag. The quality of the Kepler data is such that we can test vigorously the models for accretion disk dynamics that have been emerging in the past several years. The SC data for V344 Lyr are consistent with the model that two physical sources yield positive superhumps: early in the superoutburst. the superhump signal is generated by viscous dissipation within the periodically flexing disk. but late in the superoutburst, the signal is generated as the accretion stream bright spot sweeps around the rim of the non-axisymmetric disk. The disk super humps are roughly anti-phased with the stream/late superhumps. The V344 Lyr data also reveal negative super humps arising from accretion onto a tilted disk precessing in the retrograde direction, and suggest that negative superhumps may appear during the decline of DN outbursts. The period of negative superhumps has a positive P(raised dot) in between outbursts.

  17. The first five years of K?lauea’s summit eruption in Halema‘uma‘u Crater, 2008–2013

    USGS Publications Warehouse

    Patrick, Matthew R.; Orr, Tim R.; Sutton, Andrew J.; Elias, Tamar; Swanson, Donald A.

    2013-01-01

    The eruption in Halema‘uma‘u Crater that began in March 2008 is the longest summit eruption of K?lauea Volcano, on the Island of Hawai‘i, since 1924. From the time the eruption began, the new "Overlook crater" inside Halema‘uma‘u has exhibited fluctuating lava lake activity, occasional small explosive events, and a persistent gas plume. The beautiful nighttime glow impresses and thrills visitors in Hawai‘i Volcanoes National Park, but the continuous emission of sulfur dioxide gas produces "vog" (volcanic smog) that can severely affect communities and local agriculture downwind. U.S. Geological Survey scientists continue to closely monitor the eruption and assess ongoing hazards.

  18. XMM-Newton observations of three short period polars: V347 Pav, GG Leo and EU UMa

    E-print Network

    Gavin Ramsay; Mark Cropper; K. O. Mason; F. A. Cordova; W. Priedhorsky

    2003-09-03

    We present phase-resolved XMM_Newton data of three short period polars: V347 Pav, GG Leo and EU UMa. All three systems show one dominant accretion region which is seen for approximately half of the orbital cycle. GG Leo shows a strong dip feature in its X-ray and UV light curves which is due to absorption of X-rays from the accretion site by the accretion stream. The emission in the case of EU UMa is dominated by soft X-rays: its soft/hard X-ray ratio is amongst the highest seen in these objects. In contrast, GG Leo and V347 Pav shows a ratio consistent with that predicted by the standard shock model. We infer the mass of the white dwarf and explore the affect of restricting the energy range on the derived parameters.

  19. Orbital Periods for the SU UMa-Type Dwarf Novae UV Persei, VY Aquarii, and V1504 Cygni

    Microsoft Academic Search

    J. R. Thorstensen; C. J. Taylor

    1997-01-01

    We present mean spectra of three SU-UMa type dwarf novae and report orbital periods based on radial velocities taken near minimum light. For UV Per we find P_orb = 0.06489 +\\/- 0.00011 d (= 93.44 +\\/- 0.16 min); for V1504 Cygni, 0.06951 +\\/- 0.00005 (= 100.10 +\\/- 0.07 min), and for VY Aqr, 0.06309 +\\/- 0.00004 d (= 90.85 +\\/-

  20. Crosshole EM in steel-cased boreholes

    SciTech Connect

    Wilt, M.; Lee, K.H.; Becker, A.; Spies, B.; Wang, B.

    1996-07-01

    The application of crosshole EM methods through steel well-casing was investigated in theoretical, laboratory and field studies. A numerical code was developed that calculates the attenuation and phase delay of an EM dipole signal propagated through a steel well casing lodged in a homogeneous medium. The code was validated with a scale model and used for sensitivity studies of casing and formation properties. Finally, field measurements were made in an oil field undergoing waterflooding. Our most important findings are that (1) crosshole surveys are feasible using a well pair with one metallic and one non-metallic casing. (2) The casing effect seems be localized within the pipe section that includes the sensor. (3) The effects of the casing can be corrected using simple means and (4) crosshole field data that are sensitive to both formation and casing were acquired in a working environment.

  1. ISSN 0103-9741 Monografias em Cincia da Computao

    E-print Network

    Endler, Markus

    (cfelicissimo, sardinha, lucena)@inf.puc-rio.br Abstract. Inspired by the Tim Berners-Lee's vision of a Semantic. Inspirado pela visão de Tim Berners-Lee da Web Semântica, este trabalho vi- as apresentar uma aproximação

  2. Topic-based language models using EM

    Microsoft Academic Search

    Daniel Gildea; Thomas Hofmann

    1999-01-01

    In this paper, we propose a novel statistical language model to capture topic-related long-range dependencies. Topics are mod- eled in a latent variable framework in which we also derive an EM algorithm to perform a topic factor decomposition based on a segmented training corpus. The topic model is combined with a standard language model to be used for on-line word

  3. Simplex EMS users knock company's service support

    Microsoft Academic Search

    Cohn

    1982-01-01

    Simplex Tape Recorder Co. is not responding fast enough to please some of its energy management system (EMS) users who need service or new parts. The users complain that Simplex load-shedding, time-of-day control, and duty-cycling functions do not compare with the quality of its security and fire functions. Company spokesmen claim that service and parts are available on a 24-hour

  4. Helicopter EMS: Research Endpoints and Potential Benefits

    PubMed Central

    Thomas, Stephen H.; Arthur, Annette O.

    2012-01-01

    Patients, EMS systems, and healthcare regions benefit from Helicopter EMS (HEMS) utilization. This article discusses these benefits in terms of specific endpoints utilized in research projects. The endpoint of interest, be it primary, secondary, or surrogate, is important to understand in the deployment of HEMS resources or in planning further HEMS outcomes research. The most important outcomes are those which show potential benefits to the patients, such as functional survival, pain relief, and earlier ALS care. Case reports are also important “outcomes” publications. The benefits of HEMS in the rural setting is the ability to provide timely access to Level I or Level II trauma centers and in nontrauma, interfacility transport of cardiac, stroke, and even sepsis patients. Many HEMS crews have pharmacologic and procedural capabilities that bring a different level of care to a trauma scene or small referring hospital, especially in the rural setting. Regional healthcare and EMS system's benefit from HEMS by their capability to extend the advanced level of care throughout a region, provide a “backup” for areas with limited ALS coverage, minimize transport times, make available direct transport to specialized centers, and offer flexibility of transport in overloaded hospital systems. PMID:22203905

  5. Analysis of Three SU UMa-Type Dwarf Novae in the Kepler Field

    NASA Astrophysics Data System (ADS)

    Kato, Taichi; Osaki, Yoji

    2013-10-01

    We studied Kepler light curves of three SU UMa-type dwarf novae: a background dwarf nova of KIC 4378554, V585 Lyr, and V516 Lyr. Both the background dwarf nova and V516 Lyr showed a combination of a precursor and a main superoutburst, during which superhumps always developed in the fading branch of the precursor. This finding supports that the thermal-tidal instability theory explains the origin of superoutburst. A superoutburst of V585 Lyr recorded by Kepler did not show a precursor outburst, and the superhumps developed only after the maximum light: namely, the first-ever example in the Kepler data. Such a superoutburst is understood based on the thermal-tidal instability model to be a ``case B'' superoutburst, discussed by Osaki and Meyer (2003, A&A, 401, 325). From the observation of V585 Lyr, Kepler first clearly revealed the positive period derivative commonly seen in the ``stage B'' superhumps of dwarf novae with a short orbital period. In all three objects, there was no strong signature of a transition to the dominating stream impact-type component of superhumps. This finding suggests that there is no strong indication of an enhanced mass-transfer following the superoutburst. In V585 Lyr, there were ``mini-rebrightenings'' with an amplitude of 0.2-0.4 mag and its period of 0.4-0.6 d during the period between the superoutburst and the rebrightening. We have determined that the orbital period of V516 Lyr is 0.083999(8) d. In V516 Lyr, some of outbursts were double outbursts with varying degrees. The preceding outburst in the double was of the inside-out nature, while the following one was of the outside-in nature. One of the superoutbursts in V516 Lyr was preceded by a double precursor. The preceding precursor failed to trigger a superoutburst, and the following precursor triggered a superoutburst by developing positive superhumps. We have also developed new methods of reconstructing the light curve of superhumps, and of measuring the times of maxima from poorly sampled Kepler LC data.

  6. Suporte Interveno de Operadores no Tratamento de Excepes em Fluxos de Trabalho

    E-print Network

    Antunes, Pedro

    para suportar o envolvimento do operador criando uma plataforma integrada que permita o tratamento de uma plataforma com o objectivo de preencher esta lacuna. Esta plataforma é construída com a noção que

  7. TESE DE DOUTORADO EM ENGENHARIA DE SISTEMAS ELETRNICOS E DE AUTOMAO

    E-print Network

    de Queiroz, Ricardo L.

    TESE DE DOUTORADO EM ENGENHARIA DE SISTEMAS ELETRÔNICOS E DE AUTOMAÇÃO CODIFICAÇÃO DE VÍDEO ESCALONÁVEL EM COMPLEXIDADE E EM ENERGIA Tiago Alves da Fonseca Brasília, agosto de 2012 UNIVERSIDADE DE ENGENHARIA ELÉTRICA CODIFICAÇÃO DE VÍDEO ESCALONÁVEL EM COMPLEXIDADE E EM ENERGIA Tiago Alves da Fonseca

  8. PROGRAMA DE PS-GRADUAO EM MICROELETRNICA UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL

    E-print Network

    dos Santos, C.A.

    PROGRAMA DE PÓS-GRADUAÇÃO EM MICROELETRÔNICA PGMICRO UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL/2004 A Comissão de Pós-Graduação em Microeletrônica em reunião de 19 de março de 2004 e em Reunião do Conselho de (dez) horas de aulas ministradas ao longo do semestre, em disciplinas de graduação de 60 (sessenta

  9. PROGRAMA DE PS-GRADUAO EM MICROELETRNICA UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL

    E-print Network

    dos Santos, C.A.

    PROGRAMA DE PÓS-GRADUAÇÃO EM MICROELETRÔNICA PGMICRO UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL.inf.ufrgs.br/pgmicro Lista, em ordem alfabética, dos selecionados ao curso de Mestrado com ingresso em 2012/01 André Luiz de PósGraduação em Microeletrônica #12;PROGRAMA DE PÓS-GRADUAÇÃO EM MICROELETRÔNICA PGMICRO

  10. MICORRIZA ARBUSCULAR EM ESPÉCIES ARBÓREAS NATIVAS DA BACIA DO RIO TIBAGI, PARANÁ

    Microsoft Academic Search

    Waldemar Zangaro; Silvio M. A. Nisizaki; Juliana C. B. Domingos; Emilia M. Nakano

    RESUMO: Relata-se a incidência da colonização de micorriza arbuscular (MA) e a resposta à inocu- lação em 81 espécies arbóreas nativas da bacia do rio Tibagi (PR), em condições de casa de vegetação. Também é relatada a incidência da colonização de MA em 51 espécies arbóreas nativas coletadas em áreas em início de sucessão arbórea e no interior da floresta

  11. THE CONTROL OF FISH PARASITES AND THE ERADICATION OF ASIAN TAPEWORM INFECTIONS IN GRASS CARP USING PRAZIQUANTEL BATH TREATMENTS

    Technology Transfer Automated Retrieval System (TEKTRAN)

    There are few studies on the control of fish parasites and even fewer effective or accepted methods for the direct or indirect control of these parasites. When parasite eradication from fish stocks is the goal, the probability for success is very low. Condition of host, life cycle of parasite, wate...

  12. Cimetidine synergizes with Praziquantel to enhance the immune response of HBV DNA vaccine via activating cytotoxic CD8(+) T cell.

    PubMed

    Xie, Xiaoping; Geng, Shuang; Liu, Hu; Li, Chaofan; Yang, Yuqin; Wang, Bin

    2014-01-01

    Previously, we have reported that either CIM or PZQ, 2 clinical drugs, could be used to develop as adjuvants on HBV DNA vaccine to elicit both humoral and cellular immune responses. Here, we demonstrate that combinations of CIM and PZQ as adjuvants for a HBV DNA vaccine, could induce much stronger antigen specific CD4(+) and CD8(+) T cell responses compared either with CIM or PZQ alone. The synergistic effects of CIM plus PZQ to HBV DNA vaccine were observed on a higher IgG2a/IgG1 ratio, an increase of HBsAg-specific CD4(+) T cells capable of producing IFN-? or IL-17A and a robust IFN-?-, IL-17A-, or TNF-?-producing CD8(+) T cells to HBsAg. Most importantly, the antigen-specific CTL response was also elevated significantly, which is critical for the eradication of hepatitis B virus (HBV) infected cells. Using an HBsAg transgenic mouse model, the expression of HBsAg in the hepatic cells was also significantly reduced after immunized with pCD-S 2 in the presence of 0.5% CIM and 0.25% PZQ. Further investigations demonstrated that the synergistic effects of combination of CIM and PZQ were dependent on enhanced cytotoxic CD8(+) T cells, which was correlated with impaired activities of regulatory T cells. Therefore, combinations of CIM and PZQ have great potential to be used as effective adjuvants on DNA-based vaccinations for the treatment of chronic hepatitis B. PMID:24643207

  13. Efficacy of Droncit R Spot-on (praziquantel) 4% w\\/v against immature and mature Echinococcus multilocularis in cats

    Microsoft Academic Search

    David J Jenkins; Thomas Romig

    2000-01-01

    The causative agent of alveolar hydatidosis in humans, the fox tapeworm Echinococcusmultilocularis, is extending its geographical range in Europe and has been found in domestic cats in some areas. A dermally applied cestocidal treatment for domestic cats has been developed and the efficacy of this treatment is reported. Thirty purpose-bred cats were experimentally infected each with 10?000 protoscoleces of Echinococcusmultilocularis.

  14. UNIVERSIDADE DE BRASLIA PROGRAMA DE PS-GRADUAO EM ECONOMIA

    E-print Network

    Maier, Rudolf Richard

    UNIVERSIDADE DE BRASÍLIA PROGRAMA DE P�S-GRADUA��O EM ECONOMIA EDITAL No. 03/2013 SELE��O DE CANDIDATOS �S VAGAS DO PROGRAMA DE P�S- GRADUA��O EM ECONOMIA PARA O CURSO DE DOUTORADO ACAD�MICO PARA O PRIMEIRO SEMESTRE LETIVO DE 2014 PRE�MBULO O Coordenador do Programa de Pós-Graduação em Economia da

  15. Online EM for Unsupervised Models NAACL June 3, 2009

    E-print Network

    Pratt, Vaughan

    Online EM for Unsupervised Models NAACL ­ June 3, 2009 Percy Liang Dan Klein #12;Based on a true.2 0.4 0.6 0.8 1.0 accuracy Batch EM 2 #12;Based on a true story Part-of-speech induction: DT NNP NNP VBD The European Commission agreed 20 40 60 80 iterations 0.2 0.4 0.6 0.8 1.0 accuracy Batch EM Online

  16. CARACTERIZAÇÃO DO PERFIL DA APICULTURA EM CAPÃO BONITO E ADJACÊNCIAS

    Microsoft Academic Search

    Cristina Fachini; Ricardo Firetti; Eduardo Cardoso De Oliveira; Antonio Assiz De Carvalho Filho

    2008-01-01

    O Sudoeste Paulista é a segunda maior região do Estado em importância para a apicultura tendo totalizado em 2006 o valor de produção de R$ 3.052.402 com 17.135 colméias. Em 2006 os “produtores de mel” de Capão Bonito existiam “produtores de mel” que tinham a apicultura como principal fonte de renda até agricultores familiares que tinham a produção de mel

  17. CURSO DE PS-GRADUAO EM SENSORIAMENTO REMOTO Coordenador Acadmico

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM SENSORIAMENTO REMOTO (PGSER) Coordenador Acadêmico Elisabete Caria Moraes, Doutora, INPE, 2002 Conselho do Curso Elisabete Caria Moraes - Presidente Flávio Jorge Ponzoni - Membro

  18. CURSO DE PS-GRADUAO EM SENSORIAMENTO REMOTO Coordenador Acadmico

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM SENSORIAMENTO REMOTO (PGSER) Coordenador Acadêmico Flávio Jorge Ponzoni, Doutor, UFPR, 1993 Conselho do Curso Flávio Jorge Ponzoni - Presidente Mauricio Alves Moreira - Membro

  19. Analysis and applicability of the Dutch EMS system into countries developing EMS systems.

    PubMed

    Dib, Joe E; Naderi, Sassan; Sheridan, Indrani A; Alagappan, Kumar

    2006-01-01

    Development of an Emergency Medical Services (EMS) system is a challenging task for administrators, government agencies, and politicians. Factors such as the political climate, governmental support, and monetary resources heavily influence and shape the development of an EMS system. There are various systems in place to meet the functional needs and abilities of different regions while maintaining the basic principle of providing fast attention to those in need, and transportation to a definitive care facility. In this report, we describe the current Dutch EMS system in Amsterdam and the methods of daily pre-hospital health care delivery used, while exploring its potential applicability in developing nations. The Dutch EMS system is a nurse-driven triage system, both at the dispatch level and at the treatment level. Of the approximate yearly 165,000 calls received at the dispatch center, 40% of the requests were triaged based on national protocols such that no emergency ambulance dispatching was necessary. Furthermore, 30% of patients were treated at the scene, and did not subsequently require emergency transport to a definitive care facility. PMID:16434351

  20. REGIMENTO DO CURSO DE PS-GRADUAO EM ENGENHARIA E TECNOLOGIA ESPACIAIS, REA DE CONCENTRAO EM

    E-print Network

    direito a voto; que deverá ser o representante e Coordenador Acadêmico da Área de Concentração e membro do presidente em seus impedimentos temporários) com direito a voto. O coordenador do Conselho de Área de;2 III ­ um representante do Corpo Discente, com direito a voto; Art. 5o ­ Os integrantes do Conselho de

  1. O perfil do médico em formação em radiologia e diagnóstico por imagem

    Microsoft Academic Search

    Glauce Cerqueira Corrêa da Silva; Hilton Augusto Koch; Evandro Guimarães de Sousa

    2007-01-01

    OBJETIVO: Identificar diferenças no perfil psicossocial do especializando e médico residente em radiologia e diagnóstico por imagem, avaliar a aspiração profissional e as motivações internas que os influenciaram a escolher a especialidade radiologia e diagnóstico por imagem e se o nível de satisfação profissional melhora a relação médico-paciente. MATERIAIS E MÉTODOS: Foi aplicado um questionário com 26 perguntas que constava

  2. HISTÓRIA, LITERATURA E DITADURA: O CASO JOÃO PAZ EM INCIDENTE EM ANTARES

    Microsoft Academic Search

    Daniela Freitas Torres; Elaine dos Santos

    This article refers to a possible critic of the Brazilian military and dictatorial regime in the 1960´s and 1970s, trough the eyes of João Paz, a character in the novel of Erico Veríssimo, Incidente em Antares . The research, from a bibliographic point of view, has been based on recent theories that relate to facts in the History and Literature

  3. EM threat analysis for wireless systems.

    SciTech Connect

    Burkholder, R. J. (Ohio State University Electroscience Laboratory); Mariano, Robert J.; Schniter, P. (Ohio State University Electroscience Laboratory); Gupta, I. J. (Ohio State University Electroscience Laboratory)

    2006-06-01

    Modern digital radio systems are complex and must be carefully designed, especially when expected to operate in harsh propagation environments. The ability to accurately predict the effects of propagation on wireless radio performance could lead to more efficient radio designs as well as the ability to perform vulnerability analyses before and after system deployment. In this report, the authors--experts in electromagnetic (EM) modeling and wireless communication theory--describe the construction of a simulation environment that is capable of quantifying the effects of wireless propagation on the performance of digital communication.

  4. Communication - An Effective Tool for Implementing ISO 14001/EMS

    SciTech Connect

    Rachel Damewood; Bowen Huntsman

    2004-04-01

    The Idaho National Engineering and Environmental Laboratory (INEEL) received ISO 14001/EMS certification in June 2002. Communication played an effective role in implementing ISO 14001/EMS at the INEEL. This paper describes communication strategies used during the implementation and certification processes. The INEEL achieved Integrated Safety Management System (ISMS) and Voluntary Protection Program (VPP) Star status in 2001. ISMS implemented a formal process to plan and execute work. VPP facilitated worker involvement by establishing geographic units at various facilities with employee points of contact and management champions. The INEEL Environmental Management System (EMS) was developed to integrate the environmental functional area into its ISMS and VPP. Since the core functions of ISMS, VPP, and EMS are interchangeable, they were easy to integrate. Communication is essential to successfully implement an EMS. (According to ISO 14001 requirements, communication interacts with 12 other elements of the requirements.) We developed communication strategies that integrated ISMS, VPP, and EMS. For example, the ISMS, VPP, and EMS Web sites communicated messages to the work force, such as “VPP emphasizes the people side of doing business, ISMS emphasizes the system side of doing business, and EMS emphasizes the systems to protect the environment; but they all define work, identify and analyze hazards, and mitigate the hazards.” As a result of this integration, the work force supported and implemented the EMS. In addition, the INEEL established a cross-functional communication team to assist with implementing the EMS. The team included members from the Training and Communication organizations, VPP office, Pollution Prevention, Employee and Media Relations, a union representative, facility environmental support, and EMS staff. This crossfunctional team used various communication strategies to promote our EMS to all organization levels and successfully implemented EMS activities through VPP geographic units. In summary, the ISMS and VPP process at the INEEL provided the basic framework of management support and worker involvement to implement our EMS. A cross-functional communication team was established to facilitate the implementation with great success. Communication has been an effective tool for implementing an ISO 14001/EMS at the INEEL.

  5. AVALIAÇÃO DA PRESENÇA DE ENDOSSIMBIONTES Cardinium em DIFERENTES ESPÉCIES DE ARTRÓPODES.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A presença de endossimbiontes do gênero Cardinium em alguns grupos de artrópodes foi recentemente relatada e relacionada com diversas alterações reprodutivas em seus hospedeiros, tais como feminilização de ácaros, partenogênese em parasitóides, incompatibilidade citoplasmática e aumento da fecundida...

  6. Photometric Analyses and Spectral Identification of the Early-Spectral Type W UMa Contact Binary V444 Andromedae

    NASA Astrophysics Data System (ADS)

    Samec, R. G.; Robb, R.; Faulkner, D. R.; Van Hamme, W.

    2015-06-01

    Presented here are the first precision UBVRcIc light curves, synthetic light curve solutions, a period study, and spectrum for V444 Andromedae, an F0V contact W UMa binary. Observations were taken with the Lowell Observatory 0.81-m reflector during 28 through 30 September 2012. From our period study we determined a linear ephemeris showing that the period has been stable over the past 9.6 years (~7,500 orbits). The period during this interval is 0.46877942 d. After a q-search, the lowest residual mass ratio was found to be 0.48 with a Roche-lobe fill-out of nearly 51%. Despite its rather high temperature, 7,300 K, two magnetic spots were modeled on the primary component, a 10° radius equatorial dark spot with a T-factor of 0.88 and a 23° radius near-polar hot spot of T-factor 1.10. The component temperature difference was only ~80 K. These parameters point to a mature, early type, W UMa binary.

  7. Comparing the precision 2009 and 2012 light curves of the precontact W UMa binary V1001 Cassiopeia

    SciTech Connect

    Samec, R. G. [Faculty Research Affiliate, Pisgah Astronomical Research Institute, One Pari Drive, Rosman, NC 28772 (United States); Koenke, S. S. [Physics and Engineering Dept., Bob Jones University, 1700 Wade Hampton Boulevard, Greenville, SC 29614 (United States); Faulkner, D. R. [University of South Carolina Lancaster, 476 Hubbard Drive, Lancaster SC 29720 (United States)

    2015-01-01

    A 2012 follow up to the analysis of 2009 observations is presented for the very short period (?0.43 days) precontact W UMa binary (PCWB) V1001 Cassiopeia. Its short period, similar to the majority of W UMa binaries, and its distinct EA light curve make it a very rare and interesting system for continuing photometric investigation. Previous photometric VRI standard magnitudes give a K4 spectral type. Our solutions of light curves separated by some three years give approximately the same physical parameters. However, the spots have radically changed in temperature, area, and position. While only one dark spot was used to model the first curves, two hot spots are now needed. This affects the overall shape of the light curve, especially in the secondary eclipses in B and V. Additional eclipse timings now show that the orbital period is changing. We conclude that spots are very active on this solar-type dwarf system and that it may mimic its larger cousins, the RS CVn binaries. The conclusion is that analysis now needs to be directed at the continuous time evolution of PCWBs.

  8. Photometric Analyses and Spectral Identification of the Early-Spectral Type W UMa Contact Binary V444 Andromedae

    NASA Astrophysics Data System (ADS)

    Samec, R. G.; Robb, R.; Faulkner, D. R.; Van Hamme, W.

    2015-02-01

    Presented here are the first precision UBVRcIc light curves, synthetic light curve solutions, a period study, and spectrum for V444 Andromedae, an F0V contact W UMa binary. Observations were taken with the Lowell Observatory 0.81-m reflector during 28 through 30 September 2012. From our period study we determined a linear ephemeris showing that the period has been stable over the past 9.6 years (~7,500 orbits). The period during this interval is 0.46877942 d. After a q-search, the lowest residual mass ratio was found to be 0.48 with a Roche-lobe fill-out of nearly 51%. Despite its rather high temperature, 7,300 K, two magnetic spots were modeled on the primary component, a 10° radius equatorial dark spot with a T-factor of 0.88 and a 23° radius near-polar hot spot of T-factor 1.10. The component temperature difference was only ~80 K. These parameters point to a mature, early type, W UMa binary.

  9. Comparing the Precision 2009 and 2012 Light Curves of the Precontact W Uma Binary V1001 Cassiopeia

    NASA Astrophysics Data System (ADS)

    Samec, R. G.; Koenke, S. S.; Faulkner, D. R.

    2015-01-01

    A 2012 follow up to the analysis of 2009 observations is presented for the very short period (˜0.43 days) precontact W UMa binary (PCWB) V1001 Cassiopeia. Its short period, similar to the majority of W UMa binaries, and its distinct EA light curve make it a very rare and interesting system for continuing photometric investigation. Previous photometric VRI standard magnitudes give a K4 spectral type. Our solutions of light curves separated by some three years give approximately the same physical parameters. However, the spots have radically changed in temperature, area, and position. While only one dark spot was used to model the first curves, two hot spots are now needed. This affects the overall shape of the light curve, especially in the secondary eclipses in B and V. Additional eclipse timings now show that the orbital period is changing. We conclude that spots are very active on this solar-type dwarf system and that it may mimic its larger cousins, the RS CVn binaries. The conclusion is that analysis now needs to be directed at the continuous time evolution of PCWBs.

  10. Ideas for On-Chip Measurement of EM Interference

    E-print Network

    Anlage, Steven

    Ideas for On-Chip Measurement of EM Interference by R. Jacob Baker Boise State University #12;Noninvasive Ckts Must not interfere with circuit operation Connect to on-chip circuitry Robust operation (tolerant to EM interference) Example: Connect measuring circuit to clock distribution tree. What happens

  11. 10 CFR Appendixes E-M to Part 52 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    10 Energy 2 2011-01-01 2011-01-01 false [Reserved] E Appendixes E-M to Part 52 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Appendixes E-M to Part 52...

  12. 10 CFR Appendixes E-M to Part 52 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    10 Energy 2 2010-01-01 2010-01-01 false [Reserved] E Appendixes E-M to Part 52 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Appendixes E-M to Part 52...

  13. UNIVERSIDADE DE BRASLIA PROGRAMA DE PS-GRADUAO EM ECOLOGIA

    E-print Network

    Maier, Rudolf Richard

    UNIVERSIDADE DE BRASÍLIA PROGRAMA DE PÓS-GRADUAÇÃO EM ECOLOGIA EDITAL No. 2/2012 SELEÇÃO DE CANDIDATOS ÀS VAGAS DO PROGRAMA DE PÓS-GRADUAÇÃO EM ECOLOGIA PARA OS CURSOS DE MESTRADO ACADÊMICO E DOUTORADO ECOLOGIA, no uso de suas atribuições legais, estabelece e torrna público as normas do processo seletivo

  14. UNIVERSIDADE DE BRASLIA PROGRAMA DE PS-GRADUAO EM ECOLOGIA

    E-print Network

    Maier, Rudolf Richard

    UNIVERSIDADE DE BRASÍLIA PROGRAMA DE PÓS-GRADUAÇÃO EM ECOLOGIA EDITAL No. 3/2012 SELEÇÃO DE CANDIDATOS ÀS VAGAS DO PROGRAMA DE PÓS-GRADUAÇÃO EM ECOLOGIA PARA OS CURSOS DE MESTRADO ACADÊMICO E DOUTORADO Ecologia, no uso de suas atribuições legais, torna público e estabelece a retificação do Edital nº 02

  15. UNIVERSIDADE DE BRASLIA PROGRAMA DE PS-GRADUAO EM ECOLOGIA

    E-print Network

    Maier, Rudolf Richard

    1 UNIVERSIDADE DE BRASÍLIA PROGRAMA DE PÓS-GRADUAÇÃO EM ECOLOGIA EDITAL No. 03/2010 SELEÇÃO DE CANDIDATOS ÀS VAGAS DO PROGRAMA DE PÓS-GRADUAÇÃO EM ECOLOGIA PARA OS CURSOS DE MESTRADO ACADÊMICO E DOUTORADO ECOLOGIA no uso de suas atribuições legais, estabelece e torna públicas as normas do processo seletivo para

  16. Asymptotic Distribution of the EMS Option Price Estimator

    Microsoft Academic Search

    Jin-Chuan Duan; Geneviève Gauthier; Jean-Guy Simonato

    2001-01-01

    Monte Carlo simulation is commonly used for computing prices of derivative securities when an analytical solution does not exist. Recently, a new simulation technique known as empirical martingale simulation (EMS) has been proposed by Duan and Simonato (1998) as a way of improving simulation accuracy. EMS has one drawback however. Because of the dependency among sample paths created by the

  17. Mecnica Eststica Introduo e Sistemas clssicos em equilbrio, ensembles: microcannico,

    E-print Network

    Stariolo, Daniel Adrián

    Mecânica Estística 2012 Súmula · Introdução e Sistemas clássicos em equilíbrio, ensembles na física e em outras ciências. · Estatísticas quânticas, sistemas de bósons: estatística de Bose-Einstein, sis- temas de férmions: estatística de Fermi-Dirac, exemplos. · Transições de fase: modelos de

  18. Motivac~ao Consist^encia: modelos baseados em dados

    E-print Network

    Rodriguez, Noemi

    Motiva¸c~ao Consist^encia: modelos baseados em dados Consist^encia: modelos baseados do cliente Implementa¸c~ao Localiza¸c~ao de r´eplicas Replica¸c~ao Sistemas Distribu´idos junho de 2013 Replica¸c~ao #12;Motiva¸c~ao Consist^encia: modelos baseados em dados Consist^encia: modelos baseados do cliente

  19. EM algorithm for sparse representation-based image inpainting

    Microsoft Academic Search

    Mohamed-jalal Fadili; Jean-luc Starck

    2005-01-01

    We introduce an expectation-maximization (EM) algorithm for image inpainting based on a penalized likelihood formulated using linear sparse representations. Taking advantage of the sparsity of representations, a regularization through a prior penalty is imposed on the reconstructed coefficients. From a statistical point of view, the inpainting can be viewed as an estimation problem with missing data. The EM framework is

  20. CURSO DE PS-GRADUAO EM ENGENHARIA E TECNOLOGIA ESPACIAIS

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE CONCENTRAÇÃO EM COMBUSTÃO E PROPULSÃO Coordenador Acadêmico do Curso Evandro Marconi Rocco Coordenador da Área de Concentração David dos, USA, 1997 Antonio Osny de Toledo do CTA/IEAV, Doutor, ITA, Brasil, 1996 #12;CURSO DE ENGENHARIA E

  1. CURSO DE PS-GRADUAO EM ENGENHARIA E TECNOLOGIA ESPACIAIS

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE CONCENTRAÇÃO EM COMBUSTÃO E PROPULSÃO Coordenador Acadêmico do Curso Evandro Marconi Rocco Coordenador da Área de Concentração David dos Mendonça do IAE/CTA, Univ. Pennsylvania, USA, 1997 #12;CURSO DE ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE

  2. EM 385-1-1, 2008 Major Changes and Rationale

    E-print Network

    US Army Corps of Engineers

    EM 385-1-1, 2008 Change #6 Major Changes and Rationale Sections 11, 18 and 16 (Cranes and Hoisting, change wording to Powered Industrial Trucks (PITs)/Forklifts and Telehandlers. All PITs and telehandlers (EM 385-1-1, Appendices I, Q and S) · Appendix I, DELETE ­ Rationale: Crane Testing Requirements

  3. ELEKTRA: Um Chatterbot para Uso em Ambiente Educacional

    Microsoft Academic Search

    Michelle Denise Leonhardt; Daiane Dorneles de Castro; Liane Margarida; Rockenbach Tarouco

    2003-01-01

    **** Resumo. A E ducação à Distância vem despertando muito interesse de pesquisadores de diversas áreas. Por isso, também vem sendo muito a bordada em congressos, workshops e seminários. Muito se discute sobre a união entre tecnologia e educação visando complementar a formação de estudantes. Com a pesquisa em Inteligência Artificial, surgiram os chatterbots. Chatterbots são programas destinados a demonstrar

  4. Institutional Design for EMS-Based Government Procurement Policies

    Microsoft Academic Search

    Matthew Potoski; Aseem Prakash

    2006-01-01

    In recent years scholars have highlighted the public policy potential of using voluntary programs based on environmental management systems (EMS) to improve firms' environmental and regulatory performance. While firms receive some benefits for joining EMS-based voluntary programs, these incentives could be strengthened if governments mandated joining such programs as a precondition for participating in government procurement. While we support Arnold

  5. accredited clinical research, EMS and non-operative

    E-print Network

    Cinabro, David

    accredited clinical research, EMS and non-operative sports fellowships to supplement our are magnified by their young wide eyes. I have had many come back to me later--most of whom I do not recall and nationally. In my short time in the SIC world, I have had the opportunity to view the other EM departments

  6. An approximate EM Homographical Iterative Closest Point algorithm

    Microsoft Academic Search

    Markus Louw; Fred Nicolls

    This paper describes an approximately expectation- maximization (EM) formulation of a homographical iterative closest point registration approach (henceforth HICP). We show that such an EM approach allows the algorithm to converge faster, and more robustly in the presence of noise. Although this algorithm can register points transformed by a more general set of linear transformations than the original Iterative Closest

  7. Cytogenetic characterization of the CHO mutant EM9

    SciTech Connect

    Dillehay, L.E.; Thompson, L.H.; Carrano, A.V.

    1983-12-12

    A remarkable property of the Chinese hamster ovary mutant EM9 is its very high baseline frequency of sister-chromatid exchange (SCE), about 110 per cell. EM9 is also hypersensitive (7-fold) to the induction of SCE by EMS. The high baseline SCE frequency in EM9 appears to be the result of a single mutational event. DNA replication in EM9 and AA8 was studied using pulse labeling and alkaline elution. After a 1 hour labeling period, the majority of the labeled DNA elutes rapidly indicating the small size of the nascent single-stranded molecules. In the absence of BradUrd substitution more than 50% of the labeled DNA is retained on the filter after a 1 hour chase.

  8. Contour extracting with combination particle filtering and EM algorithm

    NASA Astrophysics Data System (ADS)

    Meng, Bo; Zhu, Ming

    2008-03-01

    The problem of extracting continuous structures from images is a difficult issue in early pattern recognition and image processing. Tracking with contours in a filtering framework requires a dynamical model for prediction. Recently, Particle filter, is widely used because its multiple hypotheses and versatility within framework. However, the good choice of the propagation function is still its main problem. In this paper, an improved particle filter, EM-PF algorithm is proposed which using the EM (Expectation-Maximization) algorithm to learn the dynamical models. The EM algorithm can explicitly learn the parameters of the dynamical models from training sequences. The advantage of using the EM algorithm in particle filter is that it is capable of improve tracking contour by having accurate model parameters. Though the experiment results, we show how our EM-PF can be applied to produces more robust and accurate extracting.

  9. Responsabilidade Social e Estratégia Internacional: pressupostos teóricos e diretrizes para a atuação de multinacionais em países em desenvolvimento

    Microsoft Academic Search

    Eloi Junior Damke; Queila Regina Souza

    Resumo: A questão da Responsabilidade Social corporativa tem sido considerada, entre muitos autores da área da administração , como um tema de relevância crescente na formulação de estratégias empresariais. Considerando o contexto atual em que se fundamentam estas proposições, este trabalho procura relacionar alguns dos principais argumentos favoráveis e desfavoráveis à responsabilida de social das empresas privadas, em especial aquelas

  10. Photometric study of new southern SU UMa-type dwarf novae and candidates: V877 Ara, KK Tel and PU CMa

    E-print Network

    T. Kato; R. Santallo; G. Bolt; T. Richards; P. Nelson; B. Monard; M. Uemura; S. Kiyota; R. Stubbings; A. Pearce; T. Watanabe; P. Schmeer; H. Yamaoka

    2002-10-31

    We photometrically observed three dwarf novae V877 Ara, KK Tel and PU CMa. We discovered undisputed presence of superhumps in V877 Ara and KK Tel, with mean periods of 0.08411(2) d and 0.08808(3) d, respectively. Both V877 Ara and KK Tel are confirmed to belong to long-period SU UMa-type dwarf novae. In V877 Ara, we found a large decrease of the superhump period (dot(P)/P = -14.5 +/- 2.1 x 10^(-5)). There is evidence that the period of KK Tel decreased at a similar or a more exceptional rate. Coupled with the past studies of superhump period changes, these findings suggest that a previously neglected diversity of phenomena is present in long-period SU UMa-type dwarf novae. The present discovery of a diversity in long-period SU UMa-type systems would become an additional step toward a full understanding the dwarf nova phenomenon. PU CMa is shown to be an excellent candidate for an SU UMa-type dwarf nova. We examined the outburst properties of these dwarf novae, and derived characteristic outburst recurrence times. Combined with the recently published measurement of the orbital period of PU CMa, we propose that PU CMa is the first object filling the gap between the extreme WZ Sge-type and ER UMa-type stars.

  11. Hanford Site performance summary: EM funded programs

    SciTech Connect

    Edwards, C.

    1995-09-01

    Hanford performance at fiscal year end reflects a three percent unfavorable schedule variance ($46.3 million*) which was an improvement over August 1995 ($46.3 million for September versus $65.9 million for August) and is below established reporting thresholds (greater than 3 percent). The majority of the behind schedule condition (53 percent) is attributed to EM-40 (Office of Environmental Restoration [ER]) and is a result of late receipt of funds, procurement delays, and US Army Corps of Engineers (USACE) work planned but not accomplished. Other primary contributors to the behind schedule condition are associated with tank farm upgrades, high-level waste disposal and work for others (support to the US Department of Energy-Headquarters [DOE-HQ]). The remaining behind schedule condition is distributed throughout the remaining Hanford programs and do not share common causes. A breakdown of individuals listed on page 8.

  12. Episodic outgassing and lava level fluctuations at Kilauea Volcano's summit lava lake in Halema`uma`u Crater

    NASA Astrophysics Data System (ADS)

    Patrick, M. R.; Orr, T. R.; Sutton, A. J.; Lev, E.; Fee, D.

    2014-12-01

    Kilauea's ongoing summit eruption began in March 2008 and has been characterized by a lava lake deep within an enlarging pit in Halema'uma'u Crater. The level of lava in the lake has exhibited cyclic rise and fall behavior, accompanied by episodic seismic and infrasonic tremor. From 2010 on, this episodic behavior has involved the lake abruptly switching between "spattering" and "non-spattering" regimes. Spattering phases consist of spattering and passive outgassing from the lake, as well as elevated tremor and a vigorous gas plume. Non-spattering phases are associated only with passive outgassing from the lake, with unusually low tremor and a weak gas plume. Non-spattering phases usually last several hours and often correspond with the lava lake level abruptly rising, in some cases up to 20 m. We consider these episodic lava level fluctuations a type of "gas pistoning", and focus on events in 2010 and 2013-2014. We interpret the gas pistoning to be driven by shallow gas accumulation near the top of the lava lake, based on long-term multidisciplinary monitoring including seismicity, infrasound, gas emission and geochemistry, lake level and surface motion, and robust visual and time-lapse camera observations which comprise a comprehensive characterization of gas pistoning at Kilauea. Competing models for gas pistoning, such as deeply sourced gas slugs, or dynamic pressure balances, are not consistent with the gas geochemistry or other observations at Halema'uma'u. The observed spattering regime represents significant decoupling of gas bubbles in the lake, while the non-spattering regime represents gas bubbles largely coupled, and downwelling, with the circulating lava. Gas pistons reflect a slight imbalance in gas influx/outflux at the lake surface during the non-spattering phases, associated with gas accumulating beneath the lake surface. These data illustrate the complex and episodic nature of gas emission from a lava lake. Unlike other lava lakes which have cyclic behavior that is thought to be controlled by deeply sourced processes external to the lake itself, the lake at Halema`uma`u Crater provides an example of lava lake fluctuations driven by cycles of activity that are shallowly rooted.

  13. Occupational infectious disease exposures in EMS personnel.

    PubMed

    Reed, E; Daya, M R; Jui, J; Grellman, K; Gerber, L; Loveless, M O

    1993-01-01

    Reports of occupationally transmitted hepatitis B virus (HBV) and human immunodeficiency virus (HIV) prompted the Portland Bureau of Fire Rescue and Emergency Services (PFB) to institute a comprehensive program for handling and tracking on-the-job infectious disease exposures. Data were collected for a 2-year period beginning January 1, 1988, and ending December 31, 1989, utilizing verbal and written exposure reports, prehospital care reports, and PFB statistical information. Two hundred and fifty-six (256) exposures were categorized. The overall incidence of reported exposure was 4.4/1,000 emergency medical service (EMS) calls. Of these exposures, 14 (5.5%) were needle sticks, 15 (5.9%) were eye splashes, 8 (3.1%) were mucous membrane exposures, 38 (14.8%) were exposure to nonintact skin, 120 (46.9%) were exposures to intact skin, and 61 (23.8%) involved respiratory exposure only. The incidence of exposure of nonintact skin or mucous membranes to blood or body fluids and needle sticks was 1.3/1,000 EMS calls. Forty-eight individuals (64% of those incurring needle sticks, or exposure of non-intact skin or mucous membranes to blood or body fluids) were treated and followed for signs of infection. Of this group, 11 individuals (26%) previously vaccinated against hepatitis B demonstrated inadequate HBsAb titers at the time of exposure. Requests for HIV and HBV information on source patients were made for needle sticks or exposure of nonintact skin or mucous membranes to blood or high-risk body fluids. Information on the source patient's HIV status was obtained for 57% of these requests.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:8445190

  14. BVR{sub c}I{sub c} observations and analyses on V2421 Cygni, a precontact W UMa binary

    SciTech Connect

    Samec, R. G.; Shebs, Travis S. [Astronomy Group, Physics and Engineering Department, Bob Jones University, 1700 Wade Hampton Boulevard, Greenville, SC 29614 (United States); Faulkner, D. R. [University of South Carolina, Lancaster, 476 Hubbard Drive, Lancaster, SC 29720 (United States); Van Hamme, W. [Physics Department, Florida International University, 11200 SW 8th Street, Miami, FL 33199 (United States); Mathis, R. F. [Global Research Technology Corporation, Camarillo, CA 92562 (United States)

    2014-01-01

    We present the first precision BVRI light curves, synthetic light curve solutions, and a period study for the high amplitude solar type binary, V2421 Cygni. The light curves have the appearance of an Algol (EA) type; however, it is made up of dwarf solar type components in a detached mode with a period of only 0.6331 days with an amplitude of about a full magnitude, i.e., it is a precontact W UMa binary. Flare-like disruptions occur in the light curves following the primary and secondary eclipses possibly due to the line-of-sight track of a gas stream. An associated stream spot and splash spot cause bright equatorial spots on the stellar surface of the primary star. The more massive star is the gainer, making this system a classic, albeit dwarf, Algol.

  15. Síndrome Metabólica em Crianças e Adolescentes Síndrome Metabólica em Crianças e Adolescentes Síndrome Metabólica em Crianças e Adolescentes Síndrome Metabólica em Crianças e Adolescentes Síndrome Metabólica em Crianças e Adolescentes Metabolic Syndrome in Children and Adolescents

    Microsoft Academic Search

    Cristhine L. Chagas; Diego G. Figuerôa; Ênio H. Rios; Gérson Carvalho; Gustavo Mascarenhas; Ives D. Barbosa; João M. Braghiroli; João N. Tupiná; Mariana F. Miranda; Naiara A. Fraga; Luis F. Adan

    2007-01-01

    A Síndrome Metabólica caracteriza-se pela associação de fatores de risco cardiovascular, como obesidade, resistência à insulina, dislipidemia e hipertensão arterial. Sua prevalência geral em crianças e adolescentes norte-americanos é de 3-4%, mas atinge 28,7% naqueles com Índice de Massa Corpórea (IMC) = percentil 95. Observa-se que os fatores predisponentes à síndrome se manifestam desde a vida intra-uterina. Apesar de bem

  16. PROTOCOLO DE COLETA DE MATERIAL BIOLGICO PARA ESTUDOS DE GENTICA MOLECULAR EM CARNVOROS E OUTROS

    E-print Network

    Eizirik, Eduardo

    PROTOCOLO DE COLETA DE MATERIAL BIOLÓGICO PARA ESTUDOS DE GENÉTICA MOLECULAR EM CARNÍVOROS E OUTROS encontrados mortos (p. ex. em estradas), peles apreendidas e qualquer outro material disponível. Apesar de a ênfase atual de nossas pesquisas em genética ser em carnívoros neotropicais, pesquisas similares com

  17. INVERSION OF EM DATA TO RECOVER 1-D CONDUCTIVITY AND A GEOMETRIC SURVEY PARAMETER

    E-print Network

    Oldenburg, Douglas W.

    INVERSION OF EM DATA TO RECOVER 1-D CONDUCTIVITY AND A GEOMETRIC SURVEY PARAMETER By Sean Eugene electromagnetic (EM) data. There are two types of data which are of particular interest: airborne EM (AEM) and ground based horizontal loop EM (HLEM). When dealing with AEM data there is a potential for errors

  18. PROGRAMA DE PS-GRADUAO EM MICROELETRNICA UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL

    E-print Network

    dos Santos, C.A.

    PROGRAMA DE PÓS-GRADUAÇÃO EM MICROELETRÔNICA PGMICRO UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL/2007 A Comissão de Pós-Graduação em Microeletrônica, no uso de suas atribuições regimentais, em reunião realizada, para participação de alunos e professores permanentes em congressos nacionais e internacionais, e dá

  19. Polygonal Approximation of Laser Range Data Based on Perceptual Grouping and EM

    E-print Network

    Latecki, Longin Jan

    Polygonal Approximation of Laser Range Data Based on Perceptual Grouping and EM Longin Jan Latecki Maximization (EM) step. By evaluating EM approximation quality we are able to recognize a locally optimal solution, and modify the number of model components and their parameters. Consequently, EM can converge

  20. COMPORTAMENTO E CARACTERIZAO ELETROQUMICA DE MICROELETRODOS DE DIAMANTE DOPADO COM BORO EM

    E-print Network

    Ferreira, Márcia M. C.

    COMPORTAMENTO E CARACTERIZAÇÃO ELETROQUÍMICA DE MICROELETRODOS DE DIAMANTE DOPADO COM BORO EM FIO janela de potencial em meio aquoso, inércia química e excelente resistência à passivação, que é de importância considerável em eletroanalítica2 . Por outro lado, em sua maioria, os EDDB descritos na literatura

  1. Polygonal Approximation of Laser Range Data Based on Perceptual Grouping and EM

    E-print Network

    Latecki, Longin Jan

    Polygonal Approximation of Laser Range Data Based on Perceptual Grouping and EM Longin Jan Latecki to evaluate the approximation quality obtained in each Expecta- tion Maximization (EM) step. By evaluating EM components and their parameters. Consequently, EM can converge only to a globally optimal solution

  2. EM TECNOLOGIA Os recm-licenciados tm sentido a eteuada taxa

    E-print Network

    Instituto de Sistemas e Robotica

    FORMAÇÃO EM TECNOLOGIA Os recém-licenciados têm sentido a eteuada taxa de desemprego do país. No momento de escolher o curso o frequentar o gosto já não é o principal factor a ter em conta, cada ue^ mais delas a serem leccionadas também em regime pós-laboral. A oferta passa por cursos como a Licenciatura em

  3. PROGRAMA DE PS-GRADUAO EM MICROELETRNICA UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL

    E-print Network

    dos Santos, C.A.

    PROGRAMA DE PÓS-GRADUAÇÃO EM MICROELETRÔNICA PGMICRO UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL-Graduação em Microeletrônica, em reunião de 13 de agosto de 2008, Resolve - A aprovação na disciplina MIC59 obrigatória MIC02 Concepção de Circuitos em Alta Escala (VLSI), 4 créditos. Prof. Henri Ivanov Boudinov

  4. Introduction Everything observed kMeans Clustering Mixtures of Gaussians The General EM Algorithm Expectation Maximisation

    E-print Network

    Englebienne, Gwenn

    Introduction Everything observed kMeans Clustering Mixtures of Gaussians The General EM AlgorithmMeans Clustering Mixtures of Gaussians The General EM Algorithm 1 Introduction 2 Everything observed 3 k Extensions to EM #12;Introduction Everything observed kMeans Clustering Mixtures of Gaussians The General EM

  5. Can current EMS dispatch protocols identify layperson-reported sentinel conditions?

    Microsoft Academic Search

    Keith W. Neely; Jayant Eldurkar; Markley E. R. Drake

    2000-01-01

    Introduction. Managed care organizations are seeking opportunities to capitate for emergency medical services (EMS). These and others pressures are motivating EMS planners to find innovative ways to redeploy existing EMS resources. A successful redeployment of resources implies a mechanism for more carefully matching EMS resources to need than currently exists. Objective. To determine whether the methods dispatchers currently use to

  6. Medically Unnecessary Emergency Medical Services (EMS) Transports Among Children Ages 0 to 17 Years

    Microsoft Academic Search

    P. Daniel Patterson; Elizabeth G. Baxley; Janice C. Probst; James R. Hussey; Charity G. Moore

    2006-01-01

    Objectives: Estimate the prevalence of medically unnecessary Emergency Medical Services (EMS) transports among children. Methods: We linked EMS and emergency department (ED) billing records for all EMS-to-hospital transports of children originating in three counties in South Carolina between January 1, 2001 and March 31, 2003. EMS responses resulting in no transport, transports to destinations other than the ED, or multiple

  7. SOLUC ~OES PARA CONTROLO VISUAL DE MOVIMENTO: APLICAC ~AO EM SEGUIMENTO

    E-print Network

    Barreto, Joao

    , movimento direita- esquerda tamb´em designado por "eye pan", e eleva¸c~ao, movimento cima- baixo tamb´emSOLUC¸ ~OES PARA CONTROLO VISUAL DE MOVIMENTO: APLICAC¸ ~AO EM SEGUIMENTO COM VIS~AO ACTIVA Provas . . . . . . . . . . . . . . . . . . . . . . . 7 1.1.1 Seguimento com o Olho Cicl´opico . . . . . . . . . . . . 9 1.1.2 Seguimento em Verg

  8. ESTUDO DO PROCESSO DE COMPRA DE BOI EM FRIGORÍFICOS PAULISTAS

    Microsoft Academic Search

    Thiago Bernardino De Carvalho; Shirley Martins Menezes; Sergio Zen; Rosane Lucia Chicarelli Alcantara

    2008-01-01

    Embora os produtores de gado nem sempre se comportem como uma empresa, precisam agir como tal para se manter no mercado, cada vez mais concentrado e profissionalizado nas etapas seguintes à de engorda – industrialização, atacado e varejo. O desafio para o pecuarista é grande, dada a complexidade que envolve o processo de compra de gado, caracterizado pelo marketing empresarial

  9. EM algorithm estimation of TCM scheme over multipath fading

    E-print Network

    Gunawan, Wiedy

    1997-01-01

    The performance of Trellis Coded Modulation scheme via Expectation-Maximization algorithm utilizing a Kalman filter over multipath fading is presented. EM algorithm offers an easier computation than the classical ML estimation does. To get a better...

  10. CURSO DE PS-GRADUAO EM SENSORIAMENTO REMOTO Coordenador Acadmico

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM SENSORIAMENTO REMOTO (PGSER) Coordenador Acadêmico Flávio Jorge Ponzoni, Doutor, UFPR, 1993 Conselho do Curso Flávio Jorge Ponzoni - Presidente Douglas F. M. Gherardi - Membro

  11. CURSO DE PS-GRADUAO EM COMPUTAO APLICADA

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM COMPUTAÇÃO APLICADA Coordenador Acadêmico Sandra Aparecida Sandri, Dra (Workshop dos Cursos de Mestrado e Doutorado da CAP) e, obrigatoriedade de submeter trabalho a todos os

  12. EMS-Vision: a perceptual system for autonomous vehicles

    Microsoft Academic Search

    Rudolf Gregor; Michael Lützeler; Martin Pellkofer; K.-H. Siedersberger; Ernst Dieter Dickmanns

    2002-01-01

    The paper gives a survey on the new Expectation- based Multifocal Saccadic Vision (EMS-Vision) system for autonomous vehicle guidance developed at the Universität der Bundeswehr München (UBM). EMS-Vision is the third generation dynamic vision system following the 4-D approach. Its core element is a new camera arrangement, mounted on a high bandwidth pan-tilt head for active gaze control. Central knowledge

  13. Captulo 39 Operadores Lineares NaoLimitados em Espacos de

    E-print Network

    Barata, João Carlos Alves

    Jâ??anos von Neumann (1903--1957). Von Neumann tambâ??em adotou os nomes de Johann von Neumann e Johnâ?ao­limitados em espaâ?ºcos de Hilbert foi desenvolvida originalmente por von Neumann 1 no final dos anos 20 e no in limitados. O propâ??osito especâ??�fico de von Neumann era prover a entâ?ao nascente Mecâ??anica Quâ??antica de

  14. Preliminary Experiment of EM Technology on Waste Water Treatment

    Microsoft Academic Search

    Gede Ngurah Wididana

    The objective of the experiment was to investigate the effect of EM4 on improving the quality of waste water. The experiment was conducted in two locations of candy factory, viz Nestle and Trebor Companies in Jakarta. The EM4 was treated in laboratory condition to the effluent of waste water of non adjusted pH (pH 4.0) and adjusted pH (pH 7.44)

  15. A History and Informal Assessment of the <em>Slacker Astronomyem> Podcast

    NASA Astrophysics Data System (ADS)

    Price, Aaron; Gay, Pamela; Searle, Travis; Brissenden, Gina

    Slacker Astronomyem> is a weekly podcast that covers a recent astronomical news event or discovery. The show has a unique style consisting of irreverent, over-the-top humor combined with a healthy dose of hard science. According to our demographic analysis, the combination of this style and the unique podcasting distribution mechanism allows the show to reach audiences younger and busier than those reached via traditional channels. We report on the successes and challenges of the first year of the show, and provide an informal assessment of its role as a source for astronomical news and concepts for its approximately 15,500 weekly listeners.

  16. ESTIMATIVAS DA AREA DE ATRAC~AO DE SISTEMAS N~AO LINEARES COM INCERTEZAS VARIANTES NO TEMPO POR MEIO DE UMA CLASSE DE

    E-print Network

    Pota, Himanshu Roy

    on the mean value theorem in conjunction to an approximation technique of convex sets to obtain this LDI differential inclusions, linear matrix inequalities Resumo-- Este artigo prop~oe utilizar uma classe particular forma de inclus~oes diferenciais lineares ou LDIs (do ingl^es, linear differential in- clusions), sendo

  17. MF-Ontology, uma ontologia para o processo de mineração de textos MF-Ontology, an ontology for the text mining process

    Microsoft Academic Search

    Daniel de Oliveira; Fernanda Baião

    Resumo: Este artigo apresenta uma ontologia voltada para o processo de mineração de textos (também chamado de Knowledge Discovery on Texts). Esta ontologia foi desenvolvida e posteriormente acoplada a um sistema de gerência de workflows científicos (SGWf) a fim de criar um vocabulário comum entre os usuários do SGWf e incorporar mais semântica às etapas de definição e seleção dos

  18. A influência da respiração oral na oclusão dentária: uma visão geral da literatura The influence of oral breathing on dental occlusion: a literature overview

    Microsoft Academic Search

    Edna Namiko Izuka

    2008-01-01

    ResumO Introdução: A respiração oral é uma condição extremamente freqüente, particularmente na população pediátrica, e acredi- ta-se que ao longo do tempo, ela possa influenciar o padrão de desenvolvimento das estruturas craniofaciais, levando às alterações importantes da oclusão dentária. Objetivo: Veri- ficar os aspectos diagnósticos e preventivos da má oclusão dentária secundária à respiração oral na literatura científica. Método: Revisão

  19. Uma experiência educacional de incentivo ao aleitamento materno e estimulação do bebê, para mães de nível sócio-econômico baixo: estudo preliminar

    Microsoft Academic Search

    Victoria Garcia-Montrone; Júlio C. de Rose

    1996-01-01

    Resumo Este estudo efetuou uma avaliação preliminar da eficácia de um programa educacio- nal de estímulo ao aleitamento materno, que inclui a introdução simultânea de técnicas de esti- mulação do bebê. O programa, elaborado por Garcia-Montrone (1992), foi aplicado a um grupo de mães de nível sócio-econômico baixo (grupo experimental). Tal programa foi avaliado atra- vés de sessões de observação

  20. Die erste Roboter-Lichtkurve in B und V des langperiodischen W UMa Sterns V541 Cas. Mein Lichtkurven-Roboter.

    NASA Astrophysics Data System (ADS)

    Braune, W.; Agerer, F.

    The W UMa type star V541 Cas with the long period of about 0d.91 was observed with a primary minimum in V and B in October 1987. It was the first minimum of the first robot that the BAV member F. Agerer had constructed. Details of the function are given.

  1. Regras para atribuio e renovao de bolsas CAPES e CNPq Art. 1 Os cursos de ps-graduao em nvel de mestrado e doutorado em Computao Aplicada (CAP)

    E-print Network

    Regras para atribuição e renovação de bolsas CAPES e CNPq Art. 1º ­ Os cursos de pós-graduação em nível de mestrado e doutorado em Computação Aplicada (CAP) do Instituto Nacional de Pesquisas Espaciais a sua proposta de dissertação em até 15 (quinze) meses após o seu ingresso no programa; Art. 3º ­ Não

  2. Mais de metade do total de investigadores do Pas est no ensino superior. Estes passaram de 50%, em

    E-print Network

    Instituto de Sistemas e Robotica

    %, em 1995, para 62%, em 2010 Maria Joio Alexandre Ao longo dos últimos anos, a des- pesa das empresas privadas em investigação e desenvolvimen- to (I6D) aumentou. E, ao contrário do Estado, os gastos em investigação diminuíram. É, assim, natural que o número de investigadores doutorados em atividades de I6D

  3. Degradation of Benzodiazepines after 120 Days of EMS Deployment

    PubMed Central

    McMullan, Jason T.; Jones, Elizabeth; Barnhart, Bruce; Denninghoff, Kurt; Spaite, Daniel; Zaleski, Erin; Silbergleit, Robert

    2014-01-01

    Introduction EMS treatment of status epilepticus improves outcomes, but the benzodiazepine best suited for EMS use is unclear, given potential high environmental temperature exposures. Objective To describe the degradation of diazepam, lorazepam, and midazolam as a function of temperature exposure and time over 120 days of storage on active EMS units. Methods Study boxes containing vials of diazepam, lorazepam, and midazolam were distributed to 4 active EMS units in each of 2 EMS systems in the southwestern United States during May–August 2011. The boxes logged temperature every minute and were stored in EMS units per local agency policy. Two vials of each drug were removed from each box at 30-day intervals and underwent high-performance liquid chromatography to determine drug concentration. Concentration was analyzed as mean (and 95%CI) percent of initial labeled concentration as a function of time and mean kinetic temperature (MKT). Results 192 samples were collected (2 samples of each drug from each of 4 units per city at 4 time-points). After 120 days, the mean relative concentration (95%CI) of diazepam was 97.0% (95.7–98.2%) and of midazolam was 99.0% (97.7–100.2%). Lorazepam experienced modest degradation by 60 days (95.6% [91.6–99.5%]) and substantial degradation at 90 days (90.3% [85.2-95.4%]) and 120 days (86.5% [80.7–92.3%]). Mean MKT was 31.6°C (95%CI 27.1–36.1). Increasing MKT was associated with greater degradation of lorazepam, but not midazolam or diazepam. Conclusions Midazolam and diazepam experienced minimal degradation throughout 120 days of EMS deployment in high-heat environments. Lorazepam experienced significant degradation over 120 days and appeared especially sensitive to higher MKT exposure. PMID:24548058

  4. Survey of Period Variations of Superhumps in SU UMa-Type Dwarf Novae. III. The Third Year (2010-2011)

    NASA Astrophysics Data System (ADS)

    Kato, Taichi; Maehara, Hiroyuki; Miller, Ian; Ohshima, Tomohito; Miguel, Enrique De; Tanabe, Kenji; Imamura, Kazuyoshi; Akazawa, Hidehiko; Kunitomi, Nanae; Takagi, Ryosuke; Nose, Mikiha; Hambsch, Franz-Josef; Kiyota, Seiichiro; Pavlenko, Elena P.; Baklanov, Aleksei V.; Antonyuk, Oksana I.; Samsonov, Denis; Sosnovskij, Aleksei; Antonyuk, Kirill; Andreev, Maksim V.; Morelle, Etienne; Dubovsky, Pavol A.; Kudzej, Igor; Oksanen, Arto; Masi, Gianluca; Krajci, Thomas; Pickard, Roger D.; Sabo, Richard; Itoh, Hiroshi; Stein, William; Dvorak, Shawn; Henden, Arne; Nakagawa, Shinichi; Noguchi, Ryo; Iino, Eriko; Matsumoto, Katsura; Nishitani, Hiroki; Aoki, Tomoya; Kobayashi, Hiroshi; Akasaka, Chihiro; Bolt, Greg; Shears, Jeremy; Ruiz, Javier; Shugarov, Sergey Yu.; Chochol, Drahomir; Parakhin, Nikolai A.; Monard, Berto; Shiokawa, Kazuhiko; Kasai, Kiyoshi; Staels, Bart; Miyashita, Atsushi; Starkey, Donn R.; Ögmen, Yenal; Littlefield, Colin; Katysheva, Natalia; Sergey, Ivan M.; Denisenko, Denis; Tordai, Tamas; Fidrich, Robert; Goranskij, Vitaly P.; Virtanen, Jani; Crawford, Tim; Pietz, Jochen; Koff, Robert A.; Boyd, David; Brady, Steve; James, Nick; Goff, William N.; Itagaki, Koh-Ichi; Nishimura, Hideo; Nakashima, Youichirou; Yoshida, Seiichi; Stubbings, Rod; Poyner, Gary; Maeda, Yutaka; Korotkiy, Stanislav A.; Sokolovsky, Kirill V.; Ueda, Seiji

    2012-02-01

    Continuing the project described by Kato et al. (2009, PASJ, 61, S395), we collected the times of superhump maxima for 51 SU UMa-type dwarf novae, mainly observed during the 2010-2011 season. Although most of the new data for systems with short superhump periods basically confirmed the findings by Kato et al. (ibid.) and Kato et al. (2010, PASJ, 62, 1525), the long-period system GX Cas showed an exceptionally large positive-period derivative. An analysis of public Kepler data of V344 Lyr and V1504 Cyg yielded less-striking stage transitions. In V344 Lyr, there was a prominent secondary component growing during the late stage of superoutbursts, and this component persisted for at least two more cycles of successive normal outbursts. We also investigated the superoutburst of two conspicuous eclipsing objects: HT Cas and the WZ Sge-type object SDSS J080434.20+510349.2. Strong beat phenomena were detected in both objects, and late-stage superhumps in the latter object had an almost constant luminosity during repeated rebrightenings. The WZ Sge-type object SDSS J133941.11+484727.5 showed a phase reversal around the rapid fading from the superoutburst. The object showed a prominent beat phenomenon, even after the end of the superoutburst. A pilot study of superhump amplitudes indicated that the amplitude of superhumps is strongly correlated with the orbital period, and the dependence on the inclination is weak in systems with inclinations smaller than 80°.

  5. Speciation, population structure, and demographic history of the Mojave Fringe-toed Lizard (Uma scoparia), a species of conservation concern

    PubMed Central

    Gottscho, Andrew D; Marks, Sharyn B; Jennings, W Bryan

    2014-01-01

    The North American deserts were impacted by both Neogene plate tectonics and Quaternary climatic fluctuations, yet it remains unclear how these events influenced speciation in this region. We tested published hypotheses regarding the timing and mode of speciation, population structure, and demographic history of the Mojave Fringe-toed Lizard (Uma scoparia), a sand dune specialist endemic to the Mojave Desert of California and Arizona. We sampled 109 individual lizards representing 22 insular dune localities, obtained DNA sequences for 14 nuclear loci, and found that U. scoparia has low genetic diversity relative to the U. notata species complex, comparable to that of chimpanzees and southern elephant seals. Analyses of genotypes using Bayesian clustering algorithms did not identify discrete populations within U. scoparia. Using isolation-with-migration (IM) models and a novel coalescent-based hypothesis testing approach, we estimated that U. scoparia diverged from U. notata in the Pleistocene epoch. The likelihood ratio test and the Akaike Information Criterion consistently rejected nested speciation models that included parameters for migration and population growth of U. scoparia. We reject the Neogene vicariance hypothesis for the speciation of U. scoparia and define this species as a single evolutionarily significant unit for conservation purposes. PMID:25360285

  6. THE GEOMETRY AND IONIZATION STRUCTURE OF THE WIND IN THE ECLIPSING NOVA-LIKE VARIABLES RW TRI AND UX UMa

    SciTech Connect

    Noebauer, Ulrich M.; Long, Knox S. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Sim, Stuart A. [Max Planck Institute for Astrophysics, Karl-Schwarzschild-Str. 1, 85748 Garching (Germany); Knigge, Christian [Department of Physics, University of Southampton, Southampton, S017 1BJ (United Kingdom)

    2010-08-20

    The UV spectra of nova-like variables are dominated by emission from the accretion disk, modified by scattering in a wind emanating from the disk. Here, we model the spectra of RW Tri and UX UMa, the only two eclipsing nova-like variables which have been observed with the Hubble Space Telescope in the far-ultraviolet, in an attempt to constrain the geometry and the ionization structure of their winds. Using our Monte Carlo radiative transfer code, we computed spectra for simply parameterized axisymmetric biconical outflow models and were able to find plausible models for both systems. These reproduce the primary UV resonance lines-N V, Si IV, and C IV-in the observed spectra in and out of eclipse. The distribution of these ions in the wind models is similar in both cases as is the extent of the primary scattering regions in which these lines are formed. The inferred mass-loss rates are 6%-8% of the mass accretion rates for the systems. We discuss the implication of our point models for our understanding of accretion disk winds in cataclysmic variables.

  7. Indirect evidence for short period magnetic cycles in W UMa stars. Period analysis of five overcontact systems.

    NASA Astrophysics Data System (ADS)

    Borkovits, T.; Elkhateeb, M. M.; Csizmadia, Sz.; Nuspl, J.; Bíró, I. B.; Hegedüs, T.; Csorvási, R.

    2005-10-01

    Complex period variations of five W UMa type binaries (AB And, OO Aql, DK Cyg, V566 Oph, U Peg) were investigated by analyzing their O-C diagrams, and several common features were found. Four of the five systems show secular period variations at a constant rate on the order of |dot{P}sec/P|˜10-7 yr-1. In the case of AB And, OO Aql, and U Peg a high-amplitude, nearly one-century long quasi-sinusoidal pattern was also found. It might be explained as light-time effect, or by some magnetic phenomena, although the mathematical, and consequently the physical, parameters of these fits are very problematic, as the obtained periods are very close to the length of the total data range. The most interesting feature of the studied O-C diagrams is a low amplitude ( 2-4×10-3 d) modulation with a period around 18-20 yr in four of the five cases. This phenomenon might be indirect evidence of some magnetic cycle in late-type overcontact binaries as an analog to the observed activity cycles in RS CVn systems.

  8. Speciation, population structure, and demographic history of the Mojave Fringe-toed Lizard (Uma scoparia), a species of conservation concern.

    PubMed

    Gottscho, Andrew D; Marks, Sharyn B; Jennings, W Bryan

    2014-06-01

    The North American deserts were impacted by both Neogene plate tectonics and Quaternary climatic fluctuations, yet it remains unclear how these events influenced speciation in this region. We tested published hypotheses regarding the timing and mode of speciation, population structure, and demographic history of the Mojave Fringe-toed Lizard (Uma scoparia), a sand dune specialist endemic to the Mojave Desert of California and Arizona. We sampled 109 individual lizards representing 22 insular dune localities, obtained DNA sequences for 14 nuclear loci, and found that U. scoparia has low genetic diversity relative to the U. notata species complex, comparable to that of chimpanzees and southern elephant seals. Analyses of genotypes using Bayesian clustering algorithms did not identify discrete populations within U. scoparia. Using isolation-with-migration (IM) models and a novel coalescent-based hypothesis testing approach, we estimated that U. scoparia diverged from U. notata in the Pleistocene epoch. The likelihood ratio test and the Akaike Information Criterion consistently rejected nested speciation models that included parameters for migration and population growth of U. scoparia. We reject the Neogene vicariance hypothesis for the speciation of U. scoparia and define this species as a single evolutionarily significant unit for conservation purposes. PMID:25360285

  9. Sesso Temtica: Monitoramento orbital das pastagens Brasileiras: em busca de uma pecuria mais produtiva e ambientalmente sustentvel (Orbital monitoring of the Brazilian pasturelands: in search of a more productive and environmentally sustainable cattle

    E-print Network

    of a more productive and environmentally sustainable cattle ranching). Coordenador: Dr. Laerte Guimarães cattle ranching clusters in Brazil? Specifically, in this session we will focus on three main topics: a

  10. Comorbid eating disorders in a Brazilian Attention Deficit\\/Hyperactivity Disorder adult clinical sample Transtornos alimentares comórbidos em uma amostra clínica de adultos com transtorno do déficit de atenção com hiperatividade

    Microsoft Academic Search

    Paulo Mattos; Eloisa Saboya; Vanessa Ayrão; Daniel Segenreich; Monica Duchesne; Gabriel Coutinho

    2004-01-01

    a Study Group on Attention Disorder, Institute of Psychiatry of the Federal University of Rio de Janeiro b Institute of Mental Health Studies - Federal University of Rio de Janeiro c Group on Obesity Disorders and Eating Disorders, State Institute on Diabetes and Endocrinology Abstract Abstract Abstract Abstract Abstract Although comorbidity between attention-deficit\\/hyperactivity disorder (ADHD) and eating disorders (ED) is

  11. Gerenciamento de resíduos de uma farmácia magistral situada em Vila Velha, ES: um estudo de caso* Waste management in a magistral pharmacy from Vila Velha, ES - a case study

    Microsoft Academic Search

    Cezar Spalenza; Xavier Gonçalves; Luciano Favalessa Cardoso; Ary Gomes da Silva

    SUMMARY - The destination of human activity wastes is a worldwide matter, and the organizations must establish proceedings to identify the aspects of their activities, products, and services that may be controlled in order to indicate those ones that are or may come to be significantly impacting to the environment. In order to minimize the environmen- tal impact and enhance

  12. AJUSTE AUTOMÁTICO DE RELÉS DE SOBRE-CORRENTE DURANTE O PROCESSO DE RESTABELECIMENTO DE ENERGIA ELÉTRICA. UMA TÉCNICA BASEADA EM PREVISÃO DE CARGA FRIA ATRAVÉS DE REDES NEURAIS ARTIFICIAIS

    Microsoft Academic Search

    ARTURO S. BRETAS; MAURÍCIO V. CECCON; MIGUEL MORETO; GLADIS B. SCHUCH

    After the occurrence of a Power System Blackout it is of great importance the complete restoration of load under a minimum time. This paper proposes an Automatic Overcurrent Relay Setting Scheme during System Restoration to diminish the Electric Power Supply Interruption Time. The scheme is based on cold load forecast through Artificial Neural Networks. The scheme was tested on the

  13. The Understanding of Astronomy Concepts by Students from Basic Education of a Public School. (Spanish Title: El Entendimiento de Conceptos de Aastronmía Por Los Alumnos de Educación Básica en Una Escuela Pública.) O Entendimento de Conceitos de Astronomia Por Alunos da Educa&wcedil;ão Básica: O Caso de Uma Escola Pública Brasileira

    NASA Astrophysics Data System (ADS)

    Iria Machado, Daniel; dos Santos, Carlos

    2011-07-01

    We present the results obtained in a research on the comprehension of basic astronomical concepts, in which 561 students from fifth grade middle school to third grade high school of a public school of the city of Foz do Iguaçu (Brazil) took part. A test with 20 multiple-choice questions was applied to indentify the most common conceptions expressed by the students. This test was elaborated based on the literature about misconceptions and covered the following topics: the day-night cycle; the time zones; the seasons of the year; the phases of the Moon; the movement of the Moon; the apparent movement of the Sun in the celestial sphere; the eclipses; the dimensions and distances in the Universe; the brightness of the stars and its observation from Earth. Though a small progress was verified in the proportion of scientifically acceptable answers when comparing the eighth grade of middle school to the fifth, and the third grade of high school to the first, there was an overall predominance of alternative conceptions regarding most of the explored subjects, which persisted up to the last year of secondary school. The comparison to data found in this research made in other socio-cultural contexts revealed, in many aspects, similar notions and difficulties revealed by the students. Se presentan los resultados de una investigación sobre la comprensión de conceptos astronómicos básicos, en la cual participaron 561 estudiantes que cursaban entre el quinto grado de la enseñanza primaria y el tercer año de la enseñanza secundaria de una escuela pública de la ciudad de Foz do Iguaçu (Brasil). Se utilizó un test de 20 preguntas de opción múltiple para identificar las concepciones más comunes expresadas por los estudiantes. Este instrumento de recolección de datos se desarrolló en base a la literatura sobre las concepciones alternativas y trató los siguientes temas: el ciclo día-noche, los husos horarios, las estaciones del año, las fases de la Luna, el movimiento de la Luna, el movimiento aparente del Sol sobre la esfera celeste, los eclipses, las dimensiones y las distancias en el Universo, el brillo de las estrellas y su observación de la Tierra. Si bien ha habido un pequeño progreso en la proporción de respuestas aceptables científicamente cuando se cotejó el octavo grado de la enseñanza primaria con el quinto, y el último año de la enseñanza secundaria con el primero, se observó un predominio de las concepciones alternativas en relación a la mayoría de los temas explorados, que continuó hasta los últimos años de la educación básica. Una comparación con los datos encontrados en investigaciones realizadas en otros contextos socioculturales revelaron, en muchos aspectos, conceptos y dificultades similares expresadas por los estudiantes. Apresentam-se os resultados de uma investigação sobre a compreensão de conceitos astronômicos básicos, da qual participaram 561 estudantes da quinta série do Ensino Fundamental ao terceiro ano do Ensino Médio de uma escola pública da cidade de Foz do Iguaçu. Um teste com 20 questões de múltipla escolha foi aplicado para identificar as concepções mais comuns expressadas pelos alunos. Esse instrumento de coleta de dados foi elaborado com base na literatura sobre concepções alternativas e abordou os seguintes temas: o ciclo dia-noite; os fusos horários; as estações do ano; as fases da Lua; o movimento da Lua; o movimento aparente do Sol na esfera celeste; os eclipses; as dimensões e distâncias no Universo; o brilho das estrelas e sua observação da Terra. Embora se tenha verificado um pequeno progresso na proporção de respostas cientificamente aceitáveis ao se cotejar a oitava série do Ensino Fundamental com a quinta, e a terceira série do Ensino Médio com a primeira, houve o predomínio de concepções alternativas em relação à maior parte dos temas explorados, as quais persistiram até o último ano da Educação Básica. A comparação com dados encontrados em investigações realizadas em outros contextos socioculturais revelaram, em m

  14. Representao As-Is em Engenharia Organizacional Nuno Castela

    E-print Network

    negócio As-Is tem como objectivos gerais: · Servir de base para a melhoria dos processos (e.g. TQM). · Servir de base para a inovação dos Processos (e.g. BPR) · Servir de ponto de partida para a construção de uma arquitectura de sistemas de informação (ASI). #12;· Servir de ponto de partida para a captura de

  15. ANÁLISE DA CADEIA PRODUTIVA DA CAPRINO-OVINOCULTURA EM GARANHUNS

    Microsoft Academic Search

    Daniela Moreira de Carvalho; Jalmir Pinheiro De Souza

    2008-01-01

    A caprino-ovinocultura na região Nordeste tem grande importância tanto econômica quanto social, devido ao fato dos animais terem uma boa adaptação ao clima e a alimentação, muitas vezes escassa, disponível na região. A compreensão das cadeias produtivas locais permite a proposição de melhorias no setor a fim de torná-lo mais eficiente. Na caprino-ovinocultura a eficiência ocorre através da oferta aos

  16. Descoberta de Conhecimento em Processos de Workflow Modelados e Executados sobre Plataforma Oracle

    Microsoft Academic Search

    Rafael S. Garcia; Duncan D. Ruiz

    1. Introdução Atualmente, com a necessidade cada vez maior da informatização das grandes organizações, a utilização de modelagem de processos de negócio através de alguma ferramenta de workflow vem se tornando uma prática bastante comum. Diversos processos presentes no dia-a-dia de uma grande empresa podem ser automatizados, desde a solicitação e aprovação de férias, viagens e compra de produtos, até

  17. Estado, mercado e sociedade civil: conversações em torno da responsabilidade social

    Microsoft Academic Search

    Vanessa de Souza; Travessa Nestor de Castro; Alexandre Reis; Rua Epaminondas Santos

    2004-01-01

    Resumo: O presente trabalho tem por objetivo analisar o relacionamento do empresariado com os movimentos sociais, ONGs e Estado, partindo de uma revisão da literatura pertinente a este assunto. Bem como, atualizar essa visão a partir da entrevista com uma empresária do setor de marcenaria da cidade de Porto Alegre, e de informações institucionais veiculadas no site oficial da Federação

  18. EMS Stretcher “Misadventures” in a Large, Urban EMS System: A Descriptive Analysis of Contributing Factors and Resultant Injuries

    PubMed Central

    Goodloe, Jeffrey M.; Crowder, Christopher J.; Arthur, Annette O.; Thomas, Stephen H.

    2012-01-01

    Purpose. There is a paucity of data regarding EMS stretcher-operation-related injuries. This study describes and analyzes characteristics associated with undesirable stretcher operations, with or without resultant injury in a large, urban EMS agency. Methods. In the study agency, all stretcher-related “misadventures” are required to be documented, regardless of whether injury results. All stretcher-related reports between July 1, 2009 and June 30, 2010 were queried in retrospective analysis, avoiding Hawthorne effect in stretcher operations. Results. During the year studied, 129,110 patients were transported. 23 stretcher incidents were reported (0.16 per 1,000 transports). No patient injury occurred. Four EMS providers sustained minor injuries. Among contributing aspects, the most common involved operations surrounding the stretcher-ambulance safety latch, 14/23 (60.9%). From a personnel injury prevention perspective, there exists a significant relationship between combative patients and crew injury related to stretcher operation, Fisher's exact test 0.048. Conclusions. In this large, urban EMS system, the incidence of injury related to stretcher operations in the one-year study period is markedly low, with few personnel injuries and no patient injuries incurred. Safety for EMS personnel and patients could be advanced by educational initiatives that highlight specific events and conditions contributing to stretcher-related adverse events. PMID:22606379

  19. UBVRI Photometric Study of the Totally Eclipsing 6500 K Extreme Mass Ratio W UMa Binary, GSC 3208 1986

    NASA Astrophysics Data System (ADS)

    Samec, Ronald G.; Faulkner, Danny R.; Van Hamme, Walter V.; Kring, James

    2014-06-01

    We present high precision, UBVRcIc light curves of the suspected eclipsing binary, GSC 3208 1986. The amplitudes of the light curve is very nearly 0.5 mag in all filters. The present curves are immaculate with all spot activity hidden within the low noise of the light curves. The minima are equal to within 0.1 mags. The Wilson Devinney program simultaneous light curve solution shows that this is a totally eclipsing classic A-type, EW binary. GSC 3208 1986 is an extreme mass ratio, 6500 K, W UMa system. The mass ratio is only 0.24, with a component temperature difference of only ~100K. This points to a high degree of thermal and physical contact. Indeed, the Roche lobe fill-out is 39%. The high inclination of 85° results in a long duration secondary total eclipse (an interval of constant light), some 49.5 minutes! The binary is of F6V type, and has no modeled surface discontinuities (no spots were needed in the modeling). The period study of a 13 year time duration indicates that the period is steadily decreasing. This is expected in solar type binaries undergoing magnetic braking. The variable is apparently undergoing solar-type activity with its associated magnetic breaking despite the near absence of spot distortions in the light curves. However, an early curve by Gettel et al. (2006) may give evidence for this. All indications are that this binary is mature and approaching a transitional coalescence into a fast rotating A-type star (Guinan and Bradstreet 1988).

  20. Conceptual design of the ATLAS EM muon chamber support structures

    E-print Network

    Von Boehn-Buchholz, R; Tchepournov, V; Wotschack, J

    1998-01-01

    The conceptual design of the support structures of the EM muon chambers is presented. On each side of the detector the EM chambers are arranged in four layers: one layer of MDTs and the three layers of TGCs. The chambers are mounted on four individual wheel structures per side. The four wheels are inclined by 1.23% and suspended from two longitudinal beams parallel to the beam axis. In order to allow for the opening of the ATLAS detector the wheels can be displaced longitudinally over a distance of 6 m. In addition individual wheels can be separated from each other by up to 1 m for maintenance purposes.

  1. EM Calorimeters for SoLID at Jefferson Lab

    SciTech Connect

    Z.W. Zhao, J. Huang, M. Meziane, X. Zheng, P.E. Reimer, D. Armstrong, T. Averett, W. Deconinck

    2012-12-01

    Several approved experiments at Jefferson Lab for the 12 GeV era will use the proposed Solenoid Large Intensity Device (SoLID) spectrometer. Two EM calorimeters with a total area of 15 square meters are required for electron identification and electron-pion separation. The challenge is to build calorimeters that can withstand high radiation doses in high magnetic field region and bring photon signals to low field region for readout. Several types of calorimeters were considered and we are favoring Shashlyk type as a result of balancing performance and cost. Our preliminary design and simulation of SoLID EM calorimeters are presented.

  2. EM Cygni: a study of its eclipse timings

    E-print Network

    Sz. Csizmadia; Zs. Nagy; T. Borkovits; T. Hegedus; I. B. Biro; Z. T. Kiss

    2007-09-17

    EM Cygni is a Z Cam-subtype eclipsing dwarf nova. Its orbital period variations were reported in the past but the results were in conflict to each other while other studies allowed the possibility of no period variation. In this study we report accurate new times of minima of this eclipsing binary and update its O-C diagram. We also estimate the mass transfer rate in EM Cygni system and conclude that the mass transfer is far from the critical value. The mass transfer rate determined from the eclipse timings is in agreement with the spectroscopically determined value.

  3. EM-31 Alternative and Enhanced Chemical Cleaning Program

    SciTech Connect

    King, Bill (SRNL) [SRNL

    2010-11-01

    King's introduction to his presentation made 5 important points: 1) Numerous SRS tanks scheduled for closure (contract commitments); 2) Cannot remove all sludge by mechanical means due to obstructions; 3) Chemical removal technology needed (likely oxalic acid); 4) Post - dissolution neutralization required prior to transfer to compliant tanks; 5) Sodium oxalate salts precipitate on neutralization and have negative downstream impacts. There were three SRS chemical cleaning programs in 2010: Baseline: 8wt percent OA batch contact, ECC: 1-3 wt. percent OA with oxalate destruction, and the Alternative/Enhanced Chemical Cleaning (EM-31). This talk is on the EM-31 program.

  4. 0.5setgray00.5setgray1 Determinao de coeficientes em equaes

    E-print Network

    Cipolatti, Rolci

    no primeiro equipamento de tomografia por Raios-X, constru´ido em 1972, por Hounsfield, nos laborat´orios EMI, Inglaterra. Por esses desenvolvimentos, Cormack e Hounsfield receberam o Pr^emio Nobel de medicina em 1979

  5. Determinao de Coeficientes em EDP e Gerao de Imagens para Diagnstico

    E-print Network

    Cipolatti, Rolci

    -X, constru´ido em 1972, por Hounsfield, nos laborat´orios EMI, Inglaterra. Por esses desenvolvimentos, Cormack e Hounsfield receberam o Pr^emio Nobel de medicina em 1979. . ­ p.4/19 #12;Tipos de interação de

  6. Cryo-EM structure of a 3D DNA-origami object Xiao-chen Baia

    E-print Network

    Dietz, Hendrik

    solutions free from nucleic acid stains and gel matrix residues (Fig. S2). Cryo-EM Single-Particle Analysis object was designed to be suitable for structure determination by cryo-EM single- particle analysis

  7. SubspaceEM: A fast maximum-a-posteriori algorithm for cryo-EM single particle reconstruction.

    PubMed

    Dvornek, Nicha C; Sigworth, Fred J; Tagare, Hemant D

    2015-05-01

    Single particle reconstruction methods based on the maximum-likelihood principle and the expectation-maximization (E-M) algorithm are popular because of their ability to produce high resolution structures. However, these algorithms are computationally very expensive, requiring a network of computational servers. To overcome this computational bottleneck, we propose a new mathematical framework for accelerating maximum-likelihood reconstructions. The speedup is by orders of magnitude and the proposed algorithm produces similar quality reconstructions compared to the standard maximum-likelihood formulation. Our approach uses subspace approximations of the cryo-electron microscopy (cryo-EM) data and projection images, greatly reducing the number of image transformations and comparisons that are computed. Experiments using simulated and actual cryo-EM data show that speedup in overall execution time compared to traditional maximum-likelihood reconstruction reaches factors of over 300. PMID:25839831

  8. Practice patterns of graduates of a CCFP(EM) residency program

    PubMed Central

    Varner, Catherine; Ovens, Howard; Letovsky, Eric; Borgundvaag, Bjug

    2012-01-01

    Abstract Objective To determine the practice settings of graduates of a residency program that leads to a Certificate of Special Competence in Emergency Medicine (CCFP[EM]). Design Web-based survey using standard Dillman methodology. Setting Canada. Participants All graduates of the CCFP(EM) residency training program at the University of Toronto (U of T) in Ontario between 1982 and 2009. Main outcome measures Practice type and location, job satisfaction, and nonclinical EM activities of graduates of a CCFP(EM) residency program. Results Of 146 graduates surveyed, 88 responded (response rate of 60.3%). All of the respondents indicated that they had practised EM at some point after completing the CCFP(EM) program at U of T. At survey completion, 76.7% were practising EM. Of the EM-practising cohort, 93.9% worked in urban or suburban hospitals as opposed to rural settings. Those practising EM expressed high levels of job satisfaction, with 83.3% reporting a score of 8 or higher on a 10-point satisfaction scale. Most (57.0%) of the graduates of the CCFP(EM) residency program at U of T had participated in leadership activities in EM on local, provincial, or national levels. Conclusion Most graduates of the CCFP(EM) residency program continue to practise EM, and most of them practise in urban and suburban environments. The low attrition rate of CCFP(EM) graduates should be regarded as a success of the CCFP(EM) program, and the geographic distribution of all physicians, including EM providers, warrants further study to help plan future physician resources in Canada. PMID:22798475

  9. Erros comuns de ingls em artigos cientficos escritos por pessoas de lngua portuguesa

    E-print Network

    Song, Siang Wun

    Erros comuns de inglês em artigos científicos escritos por pessoas de língua portuguesa Siang Wun comuns de inglês em artigos científicos escritos por pessoa #12;Introdução Baseado em experiência acumulada ao longo dos anos, ao revisar artigos escritos em inglês principalmente por pessoas de língua

  10. Inclusion of Astronomy Themes in an Inovative Approach of Informal Physics Teaching for High School Students. (Spanish Title: Inclusión de Temas Astronómicos en Uma Abordaje Innovadora de la Enseñanza Informal de Física Para Estudiantes de Secumdaria.) Inclusão de Temas Astronômicos Numa Abordagem Inovadora do Ensino Informal de Física Para Estudantes do Ensino Médio

    NASA Astrophysics Data System (ADS)

    Tiara Mota, Aline; de Morais Bonomini, Iracema Ariel; Meloni Martins Rosado, Ricardo

    2009-12-01

    The current work reports on an experience on Astronomy education at the Federal University of Itajubá through an extra-curricular course offered for High School students. This initiative was motivated by the low attention paid to the Astronomy subjects at this stage of the Brazilian Formal Education, in spite that the National Curricular Parameters (PCN and PCN+, in Brazil) point out the importance of their inclusion Este artículo relata una experiencia en la enseñanza de la astronomía efectuada en la Universidad Federal de Itajubá en la forma de un curso de extensión orientado para los estudiantes del colegio secundario. Esta iniciativa surgió de constatar la poca atención dada a la Astronomía en esta etapa de la Educación formal brasileña, a pesar que los Parámetros Curriculares Nacionales (PCN y PCN+, en Brasil) destacan la importancia de su inclusión. Este artigo relata uma experiência em ensino de Astronomia realizada na Universidade Federal de Itajubá na forma de um curso de extensão voltado para alunos do Ensino Médio. Esta iniciativa surgiu da pouca atenção que se dá à Astronomia nesta etapa da Educação embora os Parâmetros Curriculares Nacionais (PCN e PCN+) apontem a importância de sua inclusão.

  11. Odontologia do trabalho: Implantação da Odontologia do trabalho: Implantação da Odontologia do trabalho: Implantação da Odontologia do trabalho: Implantação da Odontologia do trabalho: Implantação da atenção em saúde bucal do trabalhador atenção em saúde bucal do trabalhador atenção em saúde bucal do trabalhador atenção em saúde bucal do trabalhador atenção em saúde bucal do trabalhador Occupational odontology: Implantation of attendance in oral health of employees

    Microsoft Academic Search

    Eduardo Pizzatto; Cléa Adas Saliba Garbin

    Key-words Vários fatores interagem determinando o nível de saúde de uma população, entre eles, a relação entre o grau de desenvolvimento do país e as condições de trabalho de seu povo. O presente trabalho tem por objetivo efetuar uma análise dos tópicos de maior pertinência no que concerne a implantação de programas de atenção odontológica voltados aos trabalhadores. Com base

  12. PREVALÊNCIA DE ENDOSSIMBIONTES Cardinium EM POPULAÇÕES DE ÁCAROS Brevipalpus phoenicis DE DIFERENTES REGIÕES BRASILEIRAS.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Em B. phoenicis (Geijskes) (Acari: Tenuipalpidae), ácaro vetor de importantes fitovírus, a presença de endossimbiontes do gênero Cardinium relaciona-se ao processo de feminilização dos machos, acarretando em elevada proporção de fêmeas em populações naturais. Até o momento, não é conhecido se este e...

  13. EmNets 2006 Life Under your Feet 1 Life Under your Feet

    E-print Network

    Amir, Yair

    EmNets 2006 Life Under your Feet 1 Life Under your Feet: A Wireless Soil Ecology Sensor Network R the Beginning... EmNets 2006 Life Under your Feet 2 · The Cast · An ecologist: Katalin Szlavecz · An undergrad Step EmNets 2006 Life Under your Feet 3 · The sensors were thoroughly tested in the lab · 2 out of 6

  14. Online EM Algorithm for Latent Data Models Olivier Cappe & Eric Moulines

    E-print Network

    Paris-Sud XI, Université de

    Online EM Algorithm for Latent Data Models Olivier Capp´e & Eric Moulines LTCI, TELECOM Paris (also sometimes called adaptive or recursive) version of the Expectation-Maximisation (EM) algorithm (1984), this approach is more directly connected to the usual EM algorithm and does not rely

  15. PROGRAMA DE PS-GRADUAO EM MICROELETRNICA UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL

    E-print Network

    dos Santos, C.A.

    PROGRAMA DE PÓS-GRADUAÇÃO EM MICROELETRÔNICA PGMICRO UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL Programa de Pós Graduação em Microeletrônica - Prédio 43412 ­ Sala 213 Av. Bento Gonçalves, 9500 - Campus.inf.ufrgs.br/pgmicro Fone/3316-6156 RESOLUÇÃO Nº 01/2007 A Comissão de Pós-Graduação em Microeletrônica, no uso de suas

  16. ANLISE DE SUPERFCIES BOMBARDEADAS POR FEIXES DE ELTRONS AUTOFOCALIZADOS EM UM SISTEMA DE PLAMA

    E-print Network

    ANÁLISE DE SUPERFÍCIES BOMBARDEADAS POR FEIXES DE ELÉTRONS AUTOFOCALIZADOS EM UM SISTEMA DE PLAMA/LAP/INPE, Orientador) RESUMO Este trabalho, iniciado em agosto de 2004, tem como objetivo a continuidade ao projeto de Iniciação Científica em andamento desde 2003, para a aplicação de pulsos rápidos de calor resultantes de

  17. PROGRAMA DE PS-GRADUAO EM MICROELETRNICA UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL

    E-print Network

    dos Santos, C.A.

    PROGRAMA DE PÓS-GRADUAÇÃO EM MICROELETRÔNICA PGMICRO UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL/2008 Esta Resolução revoga a Resolução 02/2004 de 19 de março de 2004. A Comissão de Pós-Graduação em Microeletrônica, em reunião de 13 de agosto de 2008, Resolve Incluir no currículo dos alunos do Programa de Pós

  18. Ronaldo Gonalves dos Santos QP 433 / 2001 Tpico Especiais em Fsico-Qumica de

    E-print Network

    Loh, Watson

    Ronaldo Gonçalves dos Santos QP 433 / 2001 1 QP-433 Tópico Especiais em Físico-Química de Soluões de Polímeros e Surfatantes ASSOCIAÇÃO DE ASFALTENOS EM SOLUÇÃO Ronaldo Gonçalves dos Santos 1 petróleo utiliza métodos para simplificá-lo através de processos de separação em frações com propriedades

  19. Penalized maximum-likelihood image reconstruction using space-alternating generalized EM algorithms

    Microsoft Academic Search

    Jeffrey A. Fessler; Alfred O. Hero III

    1995-01-01

    Most expectation-maximization (EM) type algorithmsfor penalized maximum-likelihood image reconstructionconverge slowly, particularly when one incorporatesadditive background effects such as scatter, random coincidences,dark current, or cosmic radiation. In addition,regularizing smoothness penalties (or priors) introduce parametercoupling, rendering intractable the M-steps of mostEM-type algorithms. This paper presents space-alternatinggeneralized EM (SAGE) algorithms for image...

  20. Equilbrio de fases em solues de polmeros 1 Termodinmica de solues de polmeros

    E-print Network

    Loh, Watson

    Equilíbrio de fases em soluções de polímeros 1 ­ Termodinâmica de soluções de polímeros A figura 1]. Figura 1: Energia livre de mistura de um sistema binário em função da composição x2. A mistura de composição p é instável e sapara-se em duas fases de composição p'e p" de energias livre de mistura menores