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1

Intestinal adhesion due to previous uterine surgery as a risk factor for delayed diagnosis of uterine rupture: a case report  

PubMed Central

Introduction Uterine rupture is a life-threatening condition both to mothers and fetuses. Its early diagnosis and treatment may save their lives. Previous myomectomy is a high risk factor for uterine rupture. Intestinal adhesion due to previous myomectomy may also prevent early diagnosis of uterine rupture. Case presentation A 38-year-old primiparous non-laboring Japanese woman with a history of myomectomy was admitted in her 34th week due to lower abdominal pain. Although the pain was slight and her vital signs were stable, computed tomography revealed massive fluid collection in her abdominal cavity, which led us to perform a laparotomy. Uterine rupture had occurred at the site of the previous myomectomy; however, the small intestine was adhered tightly to the rupture, thus masking it. The baby was delivered through a low uterine segment transverse incision. The ruptured uterine wall was reconstructed. Conclusion Intestinal adhesion due to a prior myomectomy occluded a uterine rupture, possibly masking its symptoms and signs, which may have prevented early diagnosis. PMID:22018094

2011-01-01

2

HERPETOLOGICAL NOTESHERPETOLOGICAL NOTES previously reported for any snake species.  

E-print Network

HERPETOLOGICAL NOTESHERPETOLOGICAL NOTES previously reported for any snake species. Furthermore, I snakes. I am un- certain whether or not these observations repre- sent a general behavioral of cloacal sacs]." They also suggested that cloacal hemor- rhaging in snakes may be a response to stress

Huey, Raymond B.

3

17 CFR 46.11 - Reporting of errors and omissions in previously reported data.  

...errors and omissions in previously reported data. 46.11 Section 46.11 Commodity...TRADING COMMISSION (CONTINUED) SWAP DATA RECORDKEEPING AND REPORTING REQUIREMENTS...errors and omissions in previously reported data. (a) Each swap counterparty...

2014-04-01

4

17 CFR 45.14 - Reporting of errors and omissions in previously reported data.  

Code of Federal Regulations, 2012 CFR

...errors and omissions in previously reported data. 45.14 Section 45.14 Commodity...COMMODITY FUTURES TRADING COMMISSION SWAP DATA RECORDKEEPING AND REPORTING REQUIREMENTS...errors and omissions in previously reported data. (a) Each registered entity and...

2012-04-01

5

17 CFR 45.14 - Reporting of errors and omissions in previously reported data.  

Code of Federal Regulations, 2013 CFR

...errors and omissions in previously reported data. 45.14 Section 45.14 Commodity...COMMODITY FUTURES TRADING COMMISSION SWAP DATA RECORDKEEPING AND REPORTING REQUIREMENTS...errors and omissions in previously reported data. (a) Each registered entity and...

2013-04-01

6

17 CFR 46.11 - Reporting of errors and omissions in previously reported data.  

Code of Federal Regulations, 2013 CFR

...errors and omissions in previously reported data. 46.11 Section 46.11 Commodity...COMMODITY FUTURES TRADING COMMISSION SWAP DATA RECORDKEEPING AND REPORTING REQUIREMENTS...errors and omissions in previously reported data. (a) Each swap counterparty...

2013-04-01

7

17 CFR 45.14 - Reporting of errors and omissions in previously reported data.  

...errors and omissions in previously reported data. 45.14 Section 45.14 Commodity...TRADING COMMISSION (CONTINUED) SWAP DATA RECORDKEEPING AND REPORTING REQUIREMENTS...errors and omissions in previously reported data. (a) Each registered entity and...

2014-04-01

8

Spontaneous rupture of uterus in midtrimester pregnancy due to increased uterine pressure with previous laparoscopic myomectomy.  

PubMed

Uterine rupture is a life threatening condition for both the mother and her fetus. It may be seen in the second trimester usually after induction for pregnancy termination in a scarred uterus. Spontaneous rupture in the second trimester before labor is a very rare condition. Here, we report a case of uterine rupture at 23-week pregnancy due to elevated uterine pressure with a history of laparoscopic myomectomy one year before admission. She was symptomatic for diffuse abdominal pain and the ultrasonographic image was interpreted as amniotic band. Four days later, because of deterioration of the patient and fetal bradycardia urgent laparotomy was performed. Fundal rupture with fibrotic borders suggested that a chronic event was seen. Laparoscopic myomectomy has advantages over laparatomy but the possibility of uterine rupture in following pregnancies should not be underestimated. Therefore, repair of the myometrium should be carefully assessed. PMID:24520491

Kiseli, Mine; Artas, Hakan; Armagan, Figen; Dogan, Zeynep

2013-10-01

9

Older adults who have previously fallen due to a trip walk differently than those who have fallen due to a slip.  

PubMed

Studying the relationships between centre of mass (COM) and centre of pressure (COP) during walking has been shown to be useful in determining movement stability. The aim of the current study was to compare COM-COP separation measures during walking between groups of older adults with no history of falling, and a history of falling due to tripping or slipping. Any differences between individuals who have fallen due to a slip and those who have fallen due to a trip in measures of dynamic balance could potentially indicate differences in the mechanisms responsible for falls. Forty older adults were allocated into groups based on their self-reported fall history during walking. The non-faller group had not experienced a fall in at least the previous year. Participants who had experienced a fall were split into two groups based on whether a trip or slip resulted in the fall(s). A Vicon system was used to collect full body kinematic trajectories. Two force platforms were used to measure ground reaction forces. The COM was significantly further ahead of the COP at heel strike for the trip (14.3±2.7cm) and slip (15.3±1.1cm) groups compared to the non-fallers (12.0±2.7cm). COM was significantly further behind the COP at foot flat for the slip group (-14.9±3.6cm) compared to the non-fallers (-10.3±3.9cm). At mid-swing, the COM of the trip group was ahead of the COP (0.9±1.6cm), whereas for the slip group the COM was behind the COP (-1.2±2.2cm). These results show identifiable differences in dynamic balance control of walking between older adults with a history of tripping or slipping and non-fallers. PMID:25455700

Wright, Rachel L; Peters, Derek M; Robinson, Paul D; Watt, Thomas N; Hollands, Mark A

2015-01-01

10

Prolonged asthma after smoke inhalation: A report of three cases and a review of previous reports  

SciTech Connect

The development of prolonged obstructive airways disease after smoke inhalation is of concern to fire victims and fire fighters. Three cases of asthma that developed following the inhalation of pyrolysis products are presented along with a review of previous reports of airway injury from smoke inhalation. Polyvinyl chloride pyrolysis products seem to pose a high risk, but other toxic inhalants are also implicated. There is substantial evidence that prolonged airway hyper-responsiveness and asthma may follow numerous inflammatory insults including smoke inhalation. Studies to identify specific individual risk factors and asthmagenic pyrolysis products are needed. Early, postexposure anti-inflammatory treatment may modify the outcome. 42 refs.

Moisan, T.C. (Department of Preventive Medicine, Loyola University-Stritch School of Medicine, Maywood, IL (USA))

1991-04-01

11

20 CFR 408.714 - When are reports due?  

...due? 408.714 Section 408.714 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Reporting Requirements § 408.714 When are reports due? (a) A reportable event happens....

2014-04-01

12

45 CFR 286.280 - When are annual reports due?  

Code of Federal Regulations, 2010 CFR

...2010-10-01 2010-10-01 false When are annual reports due? 286.280 Section 286.280 Public...Reporting Requirements § 286.280 When are annual reports due? (a) The annual report required by § 286.275 is due 90 days...

2010-10-01

13

45 CFR 286.280 - When are annual reports due?  

...2014-10-01 2012-10-01 true When are annual reports due? 286.280 Section 286.280 Public...Reporting Requirements § 286.280 When are annual reports due? (a) The annual report required by § 286.275 is due 90 days...

2014-10-01

14

45 CFR 286.280 - When are annual reports due?  

Code of Federal Regulations, 2012 CFR

...2012-10-01 2012-10-01 false When are annual reports due? 286.280 Section 286.280 Public...Reporting Requirements § 286.280 When are annual reports due? (a) The annual report required by § 286.275 is due 90 days...

2012-10-01

15

45 CFR 286.280 - When are annual reports due?  

Code of Federal Regulations, 2011 CFR

...2011-10-01 2011-10-01 false When are annual reports due? 286.280 Section 286.280 Public...Reporting Requirements § 286.280 When are annual reports due? (a) The annual report required by § 286.275 is due 90 days...

2011-10-01

16

45 CFR 286.280 - When are annual reports due?  

Code of Federal Regulations, 2013 CFR

...2013-10-01 2012-10-01 true When are annual reports due? 286.280 Section 286.280 Public...Reporting Requirements § 286.280 When are annual reports due? (a) The annual report required by § 286.275 is due 90 days...

2013-10-01

17

Hepatic actinomycosis: report of one case and analysis of 32 previously reported cases.  

PubMed

Hepatic actinomycosis is rare, with few published cases. There are no characteristic clinical manifestations, and computed tomography (CT) shows mainly low-density images, making clinical diagnosis difficult, and leading to frequent misdiagnosis as primary liver cancer, metastatic liver cancer or liver abscess. Diagnosis normally requires examination of both the aetiology and pathology. This article reports one male patient aged 55 who was hospitalized because of repeated upper abdominal pain for more than 2 mo. He exhibited no chills, fever or yellow staining of the skin and sclera, and examination revealed no positive signs. The routine blood results were: haemoglobin 110 g/L, normal numbers of leukocytes and neutral leukocytes, serum albumin 32 g/L, negative serum hepatitis B markers and hepatitis C antibodies, normal tumour markers (alpha-fetoprotein and carcinoembryonic antigen). An abdominal CT scan revealed an 11.2 cm × 5.8 cm × 7.4 cm mass with an unclear edge in the left liver lobe. The patient was diagnosed as having primary liver cancer, and left lobe resection was performed. The postoperative pathological examination found multifocal actinomycetes in the hepatic parenchyma, which was accompanied by chronic suppurative inflammation. A focal abscess had formed, and large doses of sodium penicillin were administered postoperatively as anti-infective therapy. This article also reviews 32 cases reported in the English literature, with the aim of determining the clinical features and treatment characteristics of this disease, and providing a reference for its diagnosis and treatment. PMID:25473199

Yang, Xing-Xiang; Lin, Jian-Mei; Xu, Kai-Ju; Wang, Shu-Qiang; Luo, Ting-Ting; Geng, Xiao-Xia; Huang, Ren-Gang; Jiang, Nan

2014-11-21

18

Laparoscopic Cholecystectomy in a Patient with Previous Pneumonectomy: A Case Report and Discussion of Anaesthetic Considerations  

PubMed Central

Increasing numbers of patients require cholecystectomy after previous pneumonectomy, but there are little data to guide anaesthetic management. A laparoscopic approach is associated with less postoperative respiratory compromise than open cholecystectomy but may be relatively contraindicated due to the undesirable effects of pneumoperitoneum on respiratory function. We describe the case of a 72-year-old patient who successfully underwent elective laparoscopic cholecystectomy 23 years after left pneumonectomy. An understanding of the combined physiological consequences of pneumonectomy and pneumoperitoneum facilitated the provision of safe and uneventful anaesthesia. We propose that laparoscopic cholecystectomy is feasible and safe to perform in patients with a single lung. PMID:25431680

Newington, Dash Faith; Ismail, Sanaa

2014-01-01

19

[A Case Report: an EML4-ALK Positive Lung Adenocarcinoma Diagnosed ?with Lymphoma Previously].  

PubMed

In recent years, with the deepening of the research of molecular biology, targeted therapy has become one of the trend of lung cancer treatment. The individualized treatment of lung cancer is attached great importance at present. Echinoderm microtubule associated protein like 4 anaplastic lymphoma kinase (EML4-ALK) as a new biological marker is a hot topic in the field of lung cancer treatment. Meanwhile, with the improvement of anticancer treatment and survival, the incidence of multiple primary carcinomas (MPC) has become increasingly. But the report that malignant lymphoma complicated with lung adenocarcinoma harboring EML4-ALK fusion gene in one individual is rare. Here, we report an EML4-ALK positive non-small cell lung cancer (NSCLC) in a patient previously diagnosed with T cell lymphoma and review literature on metachronous lung cancer complicating with lymphoma. PMID:25676402

Liu, Li; Heng, Wei

2015-02-20

20

Perivasculitic panencephalitis with relapsing polychondritis: an autopsy case report and review of previous cases.  

PubMed

We herein report an autopsy case of relapsing polychondritis encephalitis coexisting with a Lewy body pathology and also review previous autopsy cases. A 59-year-old man exhibited a tremor of the right hand, small-steppage gait and bradykinesia. Five years later, he presented with relapsing auricular chondritis and scleritis and subsequently showed exacerbation of extrapyramidal symptoms. A histological examination revealed perivascular lymphocytic cuffing and infiltration in the small vessels, as well as loss of nerve cells and gliosis in the basal ganglia, insular gyrus and medial temporal lobe. The present case was characterized by perivasculitic panencephalitis and the coexistence of a Lewy body pathology, which may have augmented the patient's parkinsonism. PMID:24881747

Niwa, Atsushi; Okamoto, Yoko; Kondo, Takayuki; Nabatame, Hidehiko; Takahashi, Ryosuke; Tomimoto, Hidekazu

2014-01-01

21

Novel Endogenous Retrovirus in Rabbits Previously Reported as Human Retrovirus 5  

PubMed Central

Human retrovirus 5 (HRV-5) represented a fragment of a novel retrovirus sequence identified in human RNA and DNA preparations. In this study, the genome of HRV-5 was cloned and sequenced and integration sites were analyzed. Using PCR and Southern hybridization, we showed that HRV-5 is not integrated into human DNA. A survey of other species revealed that HRV-5 is present in the genomic DNA of the European rabbit (Oryctolagus cuniculus) and belongs to an endogenous retrovirus family found in rabbits. The presence of rabbit sequences flanking HRV-5 proviruses in human DNA extracts suggested that rabbit DNA was present in our human extracts, and this was confirmed by PCR analysis that revealed the presence of rabbit mitochondrial DNA sequences in four of five human DNA preparations tested. The origin of the rabbit DNA and HRV-5 in human DNA preparations remains unclear, but laboratory contamination cannot explain the preferential detection of HRV-5 in inflammatory diseases and lymphomas reported previously. This is the first description of a retrovirus genome in rabbits, and sequence analysis shows that it is related to but distinct from A-type retroelements of mice and other rodents. The species distribution of HRV-5 is restricted to rabbits; other species, including other members of the order Lagomorpha, do not contain this sequence. Analysis of HRV-5 expression by Northern hybridization and reverse transcriptase PCR indicates that the virus is transcribed at a low level in many rabbit tissues. In light of these findings we propose that the sequence previously designated HRV-5 should now be denoted RERV-H (for rabbit endogenous retrovirus H). PMID:12072509

Griffiths, David J.; Voisset, Cécile; Venables, Patrick J. W.; Weiss, Robin A.

2002-01-01

22

Colonic perforation resulting from ingested chicken bone revealing previously undiagnosed colonic adenocarcinoma: report of a case and review of literature.  

PubMed

An 86 year old male with a four-day history of nonspecific gastrointestinal symptoms was found on colonoscopy to have evidence of sigmoid colon obstruction and possible perforation. Emergent operative exploration revealed diffuse peritonitis, sigmoid perforation, adjacent dense adhesions, and a foreign body protruding through the perforated area. Pathologic examination showed the foreign body to be a sliver of bone consistent with chicken bone and the sigmoid subacute perforation to be associated distally with a circumferential ulcerated obstructing mass, microscopically seen to be transmurally infiltrating adenocarcinoma, signet-ring cell type. There was extensive acute and organizing peritonitis, 100% Escherichia coli was cultured from peritoneal fluid, and the patient died two days postoperatively with sepsis and hypotension. This appears to be the fifth reported case of colonic perforation resulting from foreign body perforation due to previously undiagnosed adenocarcinoma. The four previously reported cases were all deeply invasive adenocarcinoma of sigmoid colon, and the foreign bodies included three chicken/poultry bones and a metallic staple. These five cases are highly unusual examples of a potentially lethal malignant neoplasm being clinically revealed by a usually (but not always) innocuous event, the ingestion of a small foreign body. PMID:21333012

McGregor, Douglas H; Liu, Xiaoying; Ulusarac, Ozlem; Ponnuru, Kimberly D; Schnepp, Stephanie L

2011-01-01

23

Abstract| This paper examines dynamical models for bladed-propeller type marine thrusters. Previously reported thruster dynam-  

E-print Network

| This paper examines dynamical models for bladed- propeller type marine thrusters. Previously reported of both the transient and steady-state performance of a marine thruster corroborates previously reported of marine ve- hicles enables industrial and scienti#12;c tasks such as automatic docking and station keeping

Whitcomb, Louis L.

24

Adenylosuccinate lyase (ADSL) and infantile autism: Absence of previously reported point mutation  

SciTech Connect

Autism is a heterogeneous neuropsychiatric syndrome of unknown etiology. There is evidence that a deficiency in the enzyme adenylosuccinate lyase (ADSL), essential for de novo purine biosynthesis, could be involved in the pathogenesis of certain cases. A point mutation in the ADSL gene, resulting in a predicted serine-to-proline substitution and conferring structural instability to the mutant enzyme, has been reported previously in 3 affected siblings. In order to determine the prevalence of the mutation, we PCR-amplified the exon spanning the site of this mutation from the genomic DNA of patients fulfilling DSM-III-R criteria for autistic disorder. None of the 119 patients tested were found to have this mutation. Furthermore, on preliminary screening using single-strand conformation polymorphism (SSCP), no novel mutations were detected in the coding sequence of four ADSL exons, spanning approximately 50% of the cDNA. In light of these findings, it appears that mutations in the ADSL gene represent a distinctly uncommon cause of autism. 12 refs., 2 figs.

Fon, E.A.; Sarrazin, J.; Rouleau, G.A. [Montreal General Hospital (Canada)] [and others

1995-12-18

25

Placenta Percreta Invading Broad Ligament and Parametrium in a Woman with Two Previous Cesarean Sections: A Case Report  

PubMed Central

Introduction. The incidence of placenta accreta has dramatically increased due to increasing caesarean section rate all over the world. Placenta percreta is the most severe form of placenta accretes. It frequently results in maternal morbidity and mortality mainly caused by massive obstetric hemorrhage or emergency hysterectomy. Percreta invading into the broad ligament has rarely been previously reported. Case presenting. We presented a case of placenta percreta invading left broad ligament and parametrium in a woman with two previous cesarean sections, which led to massive intraoperative hemorrhage during hysterectomy and transient ischemic encephalopathy. Conclusion. In cases of parametrial involvement, it would be more difficult to decide whether to remove placenta or leave it in site. In surgical removal neither local excision of placental bed and uterine repair nor traditional hysterectomy is adequate if parametrium invaded by placenta. We suggest delayed elective hysterectomy in such cases. So, pregnancy-induced pelvic congestion would be decreased, we can gather an expert team of gynecologists, urologists, and vascular surgeons, we could get plenty of blood products, and we may have the chance to administer methotrexate. PMID:23097727

Vahdat, Mansoureh; Mehdizadeh, Abolfazl; Sariri, Elaheh; Chaichian, Shahla; Najmi, Zahra; Kadivar, Maryam

2012-01-01

26

Appendectomy due to lead poisoning: a case-report  

Microsoft Academic Search

BACKGROUND: Lead poisoning is a common occupational health hazard in developing countries and many misdiagnoses and malpractices may occur due to unawareness of lead poisoning symptoms. CASE PRESENTATION: We report a case of occupational lead poisoning in an adult battery worker with abdominal colic who initially underwent appendectomy with removal of normal appendix. Later on he was diagnosed with lead

S Mohammadi; AH Mehrparvar; M Aghilinejad

2008-01-01

27

Inducing Score Reliability from Previous Reports: An Examination of Life Satisfaction Studies  

ERIC Educational Resources Information Center

The sample specific nature of reliability is often overlooked in substantive research, with investigators frequently referencing reliability estimates from previous studies as the basis for presuming the score integrity for their data. The purpose of the current study was to examine this practice, known as reliability induction, across studies…

Vassar, Matt; Ridge, Jason W.; Hill, Aaron D.

2008-01-01

28

Health effects of low-level radiation in shipyard workers: report of previous work  

Microsoft Academic Search

Progress over the course of the Nuclear Shipyard Workers Study is reported. The derivation of the study population, the gathering of health histories, the US Navy radiation protection program, and the determination of radiation exposures is described. (ACR)

Matanoski

1984-01-01

29

NON-DETECTION OF PREVIOUSLY REPORTED TRANSITS OF HD 97658b WITH MOST PHOTOMETRY  

SciTech Connect

The radial velocity-discovered exoplanet HD 97658b was recently announced to transit, with a derived planetary radius of 2.93 {+-} 0.28 R{sub Circled-Plus }. As a transiting super-Earth orbiting a bright star, this planet would make an attractive candidate for additional observations, including studies of its atmospheric properties. We present and analyze follow-up photometric observations of the HD 97658 system acquired with the Microvariability and Oscillations of STars space telescope. Our results show no transit with the depth and ephemeris reported in the announcement paper. For the same ephemeris, we rule out transits for a planet with radius larger than 2.09 R{sub Circled-Plus }, corresponding to the reported 3{sigma} lower limit. We also report new radial velocity measurements which continue to support the existence of an exoplanet with a period of 9.5 days, and obtain improved orbital parameters.

Dragomir, Diana; Matthews, Jaymie M.; Antoci, Victoria [Department of Physics and Astronomy, University of British Columbia, Vancouver, BC V6T1Z1 (Canada); Howard, Andrew W.; Marcy, Geoffrey W. [Department of Astronomy, University of California, Berkeley, CA 94720-3411 (United States); Henry, Gregory W. [Center of Excellence in Information Systems, Tennessee State University, 3500 John A. Merritt Blvd., Box 9501, Nashville, TN 37209 (United States); Guenther, David B. [Department of Astronomy and Physics, St. Marys University Halifax, NS B3H 3C3 (Canada); Johnson, John A. [Department of Astronomy, California Institute of Technology, 1200 East California Boulevard, MC 249-17, Pasadena, CA 91125 (United States); Kuschnig, Rainer; Weiss, Werner W. [Universitaet Wien, Institut fuer Astronomie, Tuerkenschanzstrasse 17, A1180 Wien (Austria); Moffat, Anthony F. J. [Dept de physique, Univ de Montreal C.P. 6128, Succ. Centre-Ville, Montreal, QC H3C 3J7, and Obs. du mont Megantic (Canada); Rowe, Jason F. [NASA Ames Research Center, Moffett Field, CA 94035 (United States); Rucinski, Slavek M. [Department of Astronomy and Astrophysics, University of Toronto, 50 St. George Street, Toronto, ON M5S 3H4 (Canada); Sasselov, Dimitar, E-mail: diana@phas.ubc.ca [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States)

2012-11-10

30

Tinea corporis bullosa due to Trichophyton schoenleinii: case report.  

PubMed

We report the first case of tinea corporis bullosa due to Trichophyton schoenleinii in a 41-year-old Romanian woman, without any involvement of the scalp and hair. The species identification was performed using macroscopic and microscopic features of the dermatophyte and its physiological abilities. Epidemiological aspects of the case are also discussed. The general treatment with terbinafine and topical applications of ciclopiroxolamine cream have led to complete healing, with the lesions disappearing in 2 weeks. PMID:22576942

Mare?, Mihai; N?stas?, Valentin; Apetrei, Ingrid Cezara; Suditu, Gabriela Cristina

2012-10-01

31

ACTG-HIV symptoms changes in patients switched to RPV/FTC/TDF due to previous intolerance to CART. Interim analysis of the PRO-STR study  

PubMed Central

Introduction Tolerability and convenience are crucial aspects for the long-term success of combined antiretroviral therapy (cART). The aim of this study was to investigate the impact in routine clinical practice of switching to the single tablet regimen (STR) RPV/FTC/TDF in patients with intolerance to previous cART, in terms of patients’ well-being, assessed by several validated measures. Methods Prospective, multicenter study. Adult HIV-infected patients with viral load under 1.000 copies/mL while receiving a stable ART for at least the last three months and switched to RPV/FTC/TDF due to intolerance of previous regimen, were included. Analyses were performed by ITT. Presence/magnitude of symptoms (ACTG-HIV Symptom Index), quality of life (EQ-5D, EUROQoL & MOS-HIV), adherence (SMAQ), preference of treatment and perceived ease of medication (ESTAR) through 48 weeks were performed. Results Interim analysis of 125 patients with 16 weeks of follow up was performed. 100 (80%) were male, mean age 46 years. Mean CD4 at baseline was 629.5±307.29 and 123 (98.4%) had viral load <50 copies/mL; 15% were HCV co-infected. Ninety two (73.6%) patients switched from a NNRTI (84.8% from EFV/FTC/TDF) and 33 (26.4%) from a PI/r. The most frequent reasons for switching were psychiatric disorders (51.2%), CNS adverse events (40.8%), gastrointestinal (19.2%) and metabolic disorders (19.2%). At the time of this analysis (week 16), four patients (3.2%) discontinued treatment: one due to adverse events, two virologic failures and one with no data. A total of 104 patients (83.2%) were virologically suppressed (<50 copies/mL). The average degree of discomfort in the ACTG-HIV Symptom Index significantly decreased from baseline (21±15.55) to week 4 (10.89±12.36) & week 16 (10.81±12.62), p<0.001. In all the patients, quality of life tools showed a significant benefit in well-being of the patients (Table 1). Adherence to therapy significantly and progressively increased (SMAQ) from baseline (54.4%) to week 4 (68%), p<0.001 and to week 16 (72.0%), p<0.001. Conclusions Switching to RPV/FTC/TDF from another ARV regimen due to toxicity, significantly improved the quality of life of HIV-infected patients, both in mental and physical components, and improved adherence to therapy while maintaining a good immune and virological response. PMID:25397558

Podzamczer, Daniel; Rozas, Nerea; Domingo, Pere; Ocampo, Antonio; Van den Eynde, Eva; Deig, Elisabeth; Vergara, Antonio; Knobel, Hernando; Pasquau, Juan; Antela, Antonio; Crespo, Manuel; Clotet, Bonaventure; Muñoz, Jessica; Fernandez, Pedro; Geijo, Paloma; Rodríguez de Castro, Eduardo; Diz, Julio; Casado, Araceli; Torres, Covadonga

2014-01-01

32

Large Vaginal and Bladder Calculi in a Woman With Previous Operation of Bladder Exstrophy: A Case Report  

PubMed Central

This is to report the case of a huge vaginal stone, and bladder calculi in a 26-year-old woman with previous operation of bladder exstrophy. It seems that the vaginal stone was secondary to the remaining wire used in her previous reconstructive surgery for pelvic closure 20 years ago and now surgery is performed to remove the vaginal and bladder stones. PMID:24719809

Tavakkoli, Mahmoud; Ghoreifi, Alireza

2013-01-01

33

[Somatotropic pituitary tumor in a patient with a previous ovarian strumal carcinoid. Report of one case].  

PubMed

Strumal carcinoid is an unusual form of monodermal ovarian teratoma with thyroid-like follicles mixed with typical carcinoid tumor patterns. We report a 49 years old woman presenting with an acromegaly. At the age of 45, an ovarian strumal carcinoid was excised and at three years of follow up, she complained of finger and feet growth. Laboratory showed an elevated serum IGF-1 and a sella turcica magnetic resonance imaging showed an 8 mm microadenoma. She was subjected to a transphenoidal excision and the pathological study disclosed a solid acidophilic pituitary adenoma. Two months after surgery, there was a significant decrease in serum IGT-I levels. PMID:15379334

Riedemann, Erick; Rojas, Claudio; Quevedo, Iván

2004-07-01

34

Alveolar nerve repositioning with rescue implants for management of previous treatment. A clinical report.  

PubMed

The goal of modern implant dentistry is to return patients to oral health in a rapid and predictable fashion, following a diagnostically driven treatment plan. If only a limited number of implants can be placed, or some fail and the prosthetic phase of implant dentistry is chosen to complete the patient's treatment, the final outcome may result in partial patient satisfaction and is commonly referred to as a "compromise." Previous All-on-4 implant treatment for the patient presented here resulted in a compromise, with an inadequate support system for the mandibular prosthesis and a maxillary complete denture with poor esthetics. The patient was unable to function adequately and also was disappointed with the resulting appearance. Correction of the compromised treatment consisted of bilateral inferior alveolar nerve elevation and repositioning without bone removal for lateral transposition, to gain room for rescue implants for a totally implant-supported and stabilized prosthesis. Treatment time to return the patient to satisfactory comfort, function, facial esthetics, and speech was approximately 2 weeks. The definitive mandibular prosthesis was designed for total implant support and stability with patient retrievability. Adequate space between the mandibular bar system and the soft tissue created a high water bridge effect for self-cleansing. Following a short interim mandibular healing period, the maxillary sinuses were bilaterally grafted to compensate for bone inadequacies and deficiencies for future maxillary implant reconstruction. PMID:23924033

Amet, Edward M; Uehlein, Chris

2013-12-01

35

Leiomyosarcoma of the prostate: case report and review of 54 previously published cases.  

PubMed

Prostate leiomyosarcoma is an extremely rare and highly aggressive neoplasm that accounts for less than 0.1% of primary prostate malignancies. We present a patient with primary leiomyosarcoma of the prostate and review 54 cases reported in the literature to discuss the clinical, diagnostic and therapeutic aspects of this uncommon tumor. Median survival was estimated at 17 months (95% C.I. 20.7-43.7 months) and the 1-, 3-, and 5-year actuarial survival rates were 68%, 34%, and 26%, respectively. The only factors predictive of long-term survival were negative surgical margins and absence of metastatic disease at presentation. A multidisciplinary approach is necessary for appropriate management of this dire entity. PMID:19043598

Vandoros, Gerasimos P; Manolidis, Theodoros; Karamouzis, Michalis V; Gkermpesi, Maria; Lambropoulou, Maria; Papatsoris, Athanasios G; Zachos, Ioannis; Konstantinopoulos, Panagiotis A

2008-01-01

36

Ileal intussusception due to a parasite egg: A case report  

PubMed Central

Ileal intussusception is the invagination of the small intestine within itself and accounts for 1% of cases of acute obstruction. However, physicians do not initially consider intussusception as a possible diagnosis of obstruction due to its rarity in adults. Herein, we report the case of a 22-year-old male who was admitted to the Emergency Department with continuous abdominal pain. Ultrasonography and computed tomography revealed an ileal intussusception. The patient underwent surgical removal of the segment of the small bowel. Unexpectedly, pathology revealed that the invagination occurred due to a parasite egg, with features suggestive of Schistosoma species. Schistosomiasis, although considered a parasitic disease in tropical countries, is not absent from Europe and though it is highly improbable, it may be responsible for cases of intussusception in adults. PMID:25278716

Pinto, José Pedro; Cordeiro, Agostinho; Ferreira, Ana Margarida; Antunes, Conceição; Botelho, Patrícia; Rodrigues, Ana João; Leão, Pedro

2014-01-01

37

Polymicrobial septic arthritis due to Clostridium species: case report and review.  

PubMed

Clostridium species are capable of producing several types of infectious processes, many of which have proven to be life-threatening. Septic arthritis caused by Clostridium, however, is not a very frequent finding. Currently, only 37 cases of infectious arthritis due to Clostridium species have been reported. We report a case of septic arthritis in which Clostridium perfringens, Clostridium sordellii, and Clostridium tertium were each isolated from the synovial aspirate. In addition, the 37 previously reported cases are summarized to compare the similarities and differences of the clinical course, treatment, and outcome, in order to help establish guidelines for the proper management of this infectious process. PMID:10722451

Gredlein, C M; Silverman, M L; Downey, M S

2000-03-01

38

Choleperitoneum due to intrahepatic bile duct rupture - case report.  

PubMed

Non-traumatic perforations of the bile ducts are unfrequently encountered entities, all the more when they affect the intrahepatic bile ducts, exteriorizing their biliary content in the great peritoneal cavity. Reporting such a case has determined the authors to perform a careful overview of the cases present in the literature. An observation that can be made based on these is that the obstruction of the main bile duct due to lithiasis determines, by pressure increase, the dilation of the bile system branches, all on the background of an unknown malformation of the intrahepatic bile ducts. PMID:25149621

Simion, L; Straja, Dn; Prunoiu, Vm; Alecu, M; Br?tucu, E

2014-01-01

39

Sudden death due to Eagle syndrome: a case report.  

PubMed

Eagle syndrome represents symptoms manifested by compression of regional structures by elongation of the styloid process or ossification of the stylohyoid membrane. Various theories have been put forward toward the development of Eagle syndrome. Depending on the underlying pathogenetic mechanism and the anatomical structures compressed or irritated by the elongated styloid process, symptoms vary greatly, ranging from cervicofacial pain to cerebral ischemia. Because the symptoms are variable and nonspecific, patients land up in different clinics for treatment. In the present case, the victim had previous episode of unconsciousness along with frequent headache for which she visited various clinics on numerous occasions. The elongated styloid process was appreciated during the postmortem examination, and the diagnosis of sudden death due to mechanical irritation of the carotid sinus by elongated styloid process was made as the sign of acute cardiovascular failure was present and upon exclusion of other causes of death. PMID:23949139

Kumar, Pradeep; Rayamane, Anand P; Subbaramaiah, Mouna

2013-09-01

40

Late-onset erythromelalgia in a previously healthy young woman: a case report and review of the literature  

PubMed Central

Introduction Erythromelalgia is a rare disorder characterized by episodic erythema and burning pain, which commonly involves the extremities. We present a case of late onset erythromelalgia in a previously healthy young woman and briefly review the literature. Our patient's case also has additional uncommon features not reported previously. Case presentation A 33-year-old previously healthy Caucasian woman presented with complaints of episodic burning pain and flushing occurring in a central distribution involving her face, ears, upper chest and, occasionally, her upper extremities. Her symptoms were triggered by lying down or warm temperature exposure and were relieved by cooling measures. Extensive diagnostic work-up looking for secondary causes for the symptoms was negative and the diagnosis of erythromelalgia was made based on details provided in her clinical history supported by raised temperature in the affected area measured by thermography during a symptomatic episode. The patient did not respond to pharmacological therapy or surgical sympathectomy. She was advised on lifestyle modification to avoid activities which triggered her symptoms. She was hypothermic with a core temperature between 92 and 95°F. She also had premature ovarian failure, which had not previously been reported. Conclusion Erythromelalgia is a rare disorder of unknown cause. There is no confirmatory diagnostic test; diagnosis is based on details provided in the patient's medical history and physical examination during the episodes. For those affected, this disorder leads to significant long-term morbidity and unfortunately, to date, no definitive therapy is available except for lifestyle modification. PMID:19946584

2009-01-01

41

Evidence Report: Risk of Performance Errors Due to Training Deficiencies  

NASA Technical Reports Server (NTRS)

The Risk of Performance Errors Due to Training Deficiencies is identified by the National Aeronautics and Space Administration (NASA) Human Research Program (HRP) as a recognized risk to human health and performance in space. The HRP Program Requirements Document (PRD) defines these risks. This Evidence Report provides a summary of the evidence that has been used to identify and characterize this risk. Given that training content, timing, intervals, and delivery methods must support crew task performance, and given that training paradigms will be different for long-duration missions with increased crew autonomy, there is a risk that operators will lack the skills or knowledge necessary to complete critical tasks, resulting in flight and ground crew errors and inefficiencies, failed mission and program objectives, and an increase in crew injuries.

Barshi, Immanuel

2012-01-01

42

Case Report: Bilateral diaphragmatic dysfunction due to Borrelia Burgdorferi  

PubMed Central

Summary: In this case report we describe a rare case of bilateral diaphragmatic dysfunction due to Lyme disease. Case report: A 62-years-old male presented to the hospital because of flu-like symptoms. During initial evaluation a bilateral diaphragmatic weakness with orthopnea and nocturnal hypoventilation was observed, without a known aetiology. Bilateral diaphragmatic paralysis was confirmed by fluoroscopy with a positive sniff test. The patient was referred to our centre for chronic non-invasive nocturnal ventilation (cNPPV). Subsequent investigations revealed evidence of anti- Borrelia seroactivity in EIA-IgG and IgG-blot, suggesting a recent infection with Lyme disease, and resulted in a 4-week treatment with oral doxycycline. The symptoms of nocturnal hypoventilation were successfully improved with cNPPV. However, our patient still shows impaired diaphragmatic function but he is no longer fully dependent on nocturnal ventilatory support.     Conclusion: Lyme disease should be considered in the differential diagnosis of diaphragmatic dysfunction. It is a tick-borne illness caused by one of the three pathogenic species of the spirochete Borrelia burgdorferi, present in Europe. A delay in recognizing the symptoms can negatively affect the success of treatment. Non-invasive mechanical ventilation (NIV) is considered a treatment option for patients with diaphragmatic paralysis.

Basunaid, Suhail; van der Grinten, Chris; Cobben, Nicole; Otte, Astrid; Sprooten, Roy; Gernot, Rohde

2014-01-01

43

The association of previously reported polymorphisms for microvascular complications in a meta-analysis of diabetic retinopathy.  

PubMed

We investigated the association of signals from previous GWAS and candidate gene meta-analyses for diabetic retinopathy (DR) or nephropathy (DN), as well as an EPO variant in meta-analyses of severe (SDR) and mild diabetic retinopathy (MDR). Meta-analyses of SDR (?severe non-proliferative diabetic retinopathy (NPDR) or history of panretinal photocoagulation) and MDR (?mild NPDR), defined based on seven-field stereoscopic fundus photographs, were performed in two well-characterized type 1 diabetes (T1D) cohorts: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC, n = 1,304) and Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR, n = 603). Among 34 previous signals for DR, after controlling for multiple testing, no association was replicated in our meta-analyses. rs1571942 and rs12219125 at PLXDC2 locus showed nominally significant (<0.05) association with SDR in the same direction as previous report, as did rs1801282 in PPARG gene with MDR. Among 55 loci previously associated with DN, three showed suggestive associations with SDR in our study without maintaining significance after correction for multiple testing. Of particular interest, rs1617640 (EPO) was not significantly associated with DR status, combined SDR-DN phenotype, time to SDR or time to DN (all P > 0.05). Lack of replication of previous DR hits and EPO despite reasonable statistical power implies that many of these may be false positives. Consistent with pleiotropy, we provide suggestive collective evidence for association between DR and variants previously associated with DN without reaching statistical significance at any single locus. PMID:25487307

Hosseini, S Mohsen; Boright, Andrew P; Sun, Lei; Canty, Angelo J; Bull, Shelley B; Klein, Barbara E K; Klein, Ronald; Paterson, Andrew D

2015-02-01

44

Fungemia due to Lachancea fermentati: a case report  

PubMed Central

Background Lachancea fermentati is an environmental yeast that is also used in the fermentation of alcoholic drinks. It has not previously been described as a human pathogen although the closely related yeast, Saccharomyces boulardii, can cause fungemia. Here we report a case of L. fermentati acting as a pathogen in a septic patient with cultures positive from blood, peritoneal fluid, bile, and sputum. Case presentation A 36 year-old Caucasian man was hospitalized with acute alcoholic hepatitis complicated by Escherichia coli spontaneous bacterial peritonitis. Three days after admission, he developed new fevers with sepsis requiring mechanical ventilation and vasopressor support. He was found to have a bowel perforation. Cultures from blood, peritoneal fluid, and sputum grew a difficult-to-identify yeast. Micafungin was started empirically. On hospital day 43 the yeast was identified as L. fermentati with low minimum inhibitory concentrations (by Epsilometer test) to all antifungals tested. Micafungin was changed to fluconazole to complete a 3-month course of therapy. Serial peritoneal fluid cultures remained positive for 31 days. One year after his initial hospitalization the patient had ongoing cirrhosis but had recovered from fungemia. Conclusion This case demonstrates the need for clinicians to consider host factors when interpreting culture results with normally non-pathogenic organisms. In this immunocompromised host L. fermentati caused disseminated disease. We believe his hobby of brewing alcohol led to colonization with L. fermentati, which then resulted in invasive disease when the opportunity arose. PMID:24884938

2014-01-01

45

Assessment Report 2013 Evidence collected in Spring, Summer & Fall 2012 Report due March 30, 2013  

E-print Network

practice. #12;5. Demonstrate sound clinical judgment based on the current paradigm of evidence-basedAssessment Report ­ 2013 Evidence collected in Spring, Summer & Fall 2012 Report due March 30, 2013 and effective nursing practice. 2. Integrate leadership concepts, skills, and decision making in the provision

Hemmers, Oliver

46

Rosette-forming glioneuronal tumour of the fourth ventricle with previous intratumoural haemorrhage: case report and review of the literature.  

PubMed

The case is reported of a rosette-forming glioneuronal tumour of the fourth ventricle (RGTFV) in a 27-year-old male. Symptoms included headache, severe vomiting and clumsy walking that had progressively worsened over 14 days. Computed tomography and magnetic resonance imaging indicated a 3.0 x 2.5 x 2.0 cm solid-cystic mass in the fourth ventricle and obstructive hydrocephalus. The tumour showed evidence of previous intra-tumour haemorrhage, with heterogeneous enhancement after contrast administration. Complete excision of the lesion was performed. Signs of previous intra-tumoural haemorrhage were seen intra-operatively. The detailed clinical, radiological and pathological features in this patient are described and compared with existing literature on this type of tumour. Despite benign histological features and a reported favourable post-operative course, there is still limited clinical experience with this type of tumour, however intratumoural haemorrhage may result in morbidity and mortality. This report will help provide better characterization of this entity, improving the diagnosis and potentially reducing mortality in RGTFV. PMID:19589282

Li, Y M; Li, W Q; Pan, Y; Lu, Y C; Long, N Y; Tao, X F; Yu, H Y

2009-01-01

47

Cholestasis and Seizure Due to Lead Toxicity: A Case Report  

PubMed Central

Introduction Lead poisoning is a major public health risk which may involve major organs. Recently, there have been reports of opioid adulteration with lead in Iran. The following case report is the first of its kind in that intrahepatic cholestasis due to lead toxicity has been described. Case Presentation A 65-year-old man presented to the emergency department with abdominal pain, abnormal liver function tests (cholestatic pattern), and normocytic anemia. He had been an opium user for 20 years. Clinical and preclinical findings including the bluish discoloration of periodontal tissues, or Burton’s sign, and generalized ileus on abdominal x-ray led us to the possibility of lead poisoning. Lead levels were higher than normal (150 ?g/dL). Magnetic resonance cholangiopancreatography (MRCP) and abdominal ultrasound were performed to rule out extra hepatic causes of cholestasis. To evaluate the possibility of lead-induced hepatotoxicity, a liver biopsy was performed. Histological features of lead-induced hepatotoxity have rarely been described in humans. In this patient, focal canalicular cholestasis and mild portal inflammation were confirmed. Thus, treatment with ethylenediaminetetraacetic acid (EDTA) and British anti-lewisite (BAL) were initiated and continued for five days. The patient’s liver function tests returned to their normal values, clinical findings including nausea, vomiting, and abdominal pain subsided, and the patient was discharged from the hospital in good condition. Conclusions Lead toxicity should always be taken into account in cases of intrahepatic cholestasis with an unknown etiology, especially in a setting where opium abuse is common. PMID:24348646

Mokhtarifar, Ali; Mozaffari, Hooman; Afshari, Reza; Goshayeshi, Ladan; Akavan Rezayat, Kambiz; Ghaffarzadegan, Kamran; Sheikhian, Mohammadreza; Rajabzadeh, Farnood

2013-01-01

48

Fatal anoxia due to rachacha consumption: Two cases reported.  

PubMed

Deaths due to ingesting rachacha, which is a homemade paste obtained by decocting poppy heads, are very rare. No fatalities have been recorded in scientific publications. This product is not considered to be very dangerous by its users. We are reporting the first deaths (a 30-year-old man and a 28-year-old woman), after ingesting rachacha balls and alcohol consumption during an evening with a friend. Signs compatible with acute anoxia were observed during autopsy. Toxicological analyses highlighted the presence of morphine and codeine in the blood, urine and bile, with an absence of 6-acetylmorphine. Concomitant consumption of alcohol certainly played a role in the occurrence of death. The black paste found at the scene was identified as rachacha. The mean of consumption (orally) was confirmed by the presence of morphine and codeine in the gastric contents of both victims. The analysis of hair samples was performed to reveal the substance consumption history. Therefore, a possibility of contamination by sweat and/or putrefactive liquids in the post-mortem period must be considered for the interpretation of the results. These two cases show that taking rachacha can be dangerous, especially when combined with the consumption of substances which could potentiate respiratory depression induced by morphine. PMID:25450509

Monteil-Ganiere, Catherine; Gaulier, Jean-Michel; Chopineaux, Daniel; Barrios, Lucia; Pineau, Alain; Dailly, Eric; Clément, Renaud

2014-10-01

49

Co-occurrence of Kikuchi-Fujimoto's disease and Still's disease: case report and review of previously reported cases.  

PubMed

Kikuchi-Fujimoto's disease (KFD) and adult-onset Still's disease (AOSD) are rare inflammatory conditions with some overlapping features. We encountered a 22-year-old male patient who presented with daily fevers, neck discomfort, and sore throat and subsequently developed rash, arthritis, and cervical lymphadenopathy. Biopsy of the skin rash was consistent with KFD skin involvement. Given that the patient also met criteria for AOSD, a final diagnosis of KFD/AOSD co-occurrence was made. Anti-IL-1? therapy with anakinra resulted in rapid resolution of all symptoms. A literature search identified eight more cases of KFD/AOSD. Fever, rash, arthritis, and lymphadenopathy were present in all patients. No case report demonstrated an association of rash eruption clearly associated with fever spikes. Duration of symptoms ranged from 3 weeks to 10 years. Seven patients had leukocytosis, six had anemia, and five demonstrated elevated ferritin and/or decreased glycosylated ferritin. Seven patients had elevated erythrocyte sedimentation rate (ESR), and seven had transaminitis. Eight of nine patients had no evidence of infectious disease. Autoantibodies were absent from all patients. KFD and AOSD are very rare diseases, yet they may overlap. The two conditions not only share several clinical and laboratory characteristics but also differ in characteristic ways. Given the rapid response observed with anakinra in the index patient, IL-1? likely plays a role in both diseases. PMID:25098416

Toribio, Karen A; Kamino, Hideko; Hu, Stephanie; Pomeranz, Miriam; Pillinger, Michael H

2014-08-01

50

[A nurse's experience caring for a patient with breast cancer who had been previously reported dead by her family].  

PubMed

This article describes the author's experience caring for a female with breast cancer who was reported dead by her family four years earlier due to a long-term disappearance. She had been transferred multiple times hospital to hospital due to inability to afford medical care. Data were collected via observations, interviews, and physical assessments. The author identified four primary problems, including impaired tissue integrity, pain, being compelled to abandon treatment due to financial status, desire for familial support, and sense of guilt toward her family. The author used Watson's Caring Theory to build trust with the patient and provided guidance on wound treatment, pain relief, and rebuilding family relationships in order to help restore the patient's identity and financial aid. As a result, the patient was able to transfer to a public hospital where she received free medical assistance and regained hope in her therapy. However, the palliative-care coordinator misinterpreted the referral and, as a result, experienced moral distress. After clarifying and explaining the meaning and importance of the patient referral, the coordinator accepted her and continued care. This case report can provide a reference for nurses caring for patients without personal identity or financial aid. Nurses should be aware of the presence of moral distress in other medical team members. Early recognition and timely management of team members' moral distress is fundamental to providing the best quality of care for patients and their families. PMID:21678273

Fu, Chia-Yun; Tsai, Ming-Feng; Chen, Hsing-Mei

2011-06-01

51

50 CFR 86.81 - When are the reports due?  

Code of Federal Regulations, 2011 CFR

...SPORT FISH RESTORATION PROGRAM BOATING INFRASTRUCTURE GRANT (BIG) PROGRAM Reporting Requirements for the States § 86.81...d) The State must report certified percentage of completion data and other significant developments in accordance with the...

2011-10-01

52

50 CFR 86.81 - When are the reports due?  

Code of Federal Regulations, 2010 CFR

...SPORT FISH RESTORATION PROGRAM BOATING INFRASTRUCTURE GRANT (BIG) PROGRAM Reporting Requirements for the States § 86.81...d) The State must report certified percentage of completion data and other significant developments in accordance with the...

2010-10-01

53

50 CFR 86.81 - When are the reports due?  

...SPORT FISH RESTORATION PROGRAM BOATING INFRASTRUCTURE GRANT (BIG) PROGRAM Reporting Requirements for the States § 86.81...d) The State must report certified percentage of completion data and other significant developments in accordance with the...

2014-10-01

54

50 CFR 86.81 - When are the reports due?  

Code of Federal Regulations, 2012 CFR

...SPORT FISH RESTORATION PROGRAM BOATING INFRASTRUCTURE GRANT (BIG) PROGRAM Reporting Requirements for the States § 86.81...d) The State must report certified percentage of completion data and other significant developments in accordance with the...

2012-10-01

55

50 CFR 86.81 - When are the reports due?  

Code of Federal Regulations, 2013 CFR

...SPORT FISH RESTORATION PROGRAM BOATING INFRASTRUCTURE GRANT (BIG) PROGRAM Reporting Requirements for the States § 86.81...d) The State must report certified percentage of completion data and other significant developments in accordance with the...

2013-10-01

56

[Convulsion due to application of low dose meperidine: a case report].  

PubMed

Meperidine is an opiod analgesic used in a variety of clinical situations. The active metabolite, normeperidine, is a central nervous system excitatory agent and has the ability to cause irritability, hyperreflexia, tremor, myoclonus and seizures. Previously identified risk factors for the development of meperidine-related seizures include renal failure, high meperidine dosages, and co-adminestration of hepatic enzyme inducing medications or phenothiazines which decreases seizure treshold. Patients with normal renal function rarely manifest seizure activity when given meperidine. Here we report a 10 year old boy with a femur fraction who had normal renal function. We used low dose meperidine due to post operative pains. PMID:23364782

Ozkaya, Halit; Akcan, Abdullah Bar??; Aydemir, Gökhan; Akba?, Mert

2012-01-01

57

Description of Thermococcus kodakaraensis sp. nov., a well studied hyperthermophilic archaeon previously reported as Pyrococcus sp. KOD1  

PubMed Central

A hyperthermophilic archaeal strain, KOD1, isolated from a solfatara on Kodakara Island, Japan, has previously been reported as Pyrococcus sp. KOD1. However, a detailed phylogenetic tree, made possible by the recent accumulation of 16S rRNA sequences of various species in the order Thermococcales, indicated that strain KOD1 is a member of the genus Thermococcus. We performed DNA–DNA hybridization tests against species that displayed high similarity in terms of 16S ribosomal DNA sequences, including Thermococcus peptonophilus and Thermococcus stetteri. Hybridization results and differences in growth characteristics and substrate utilization differentiated strain KOD1 from T. peptonophilus and T. stetteri at the species level. Our results indicate that strain KOD1 represents a new species of Thermococcus, which we designate as Thermococcus kodakaraensis KOD1 sp. nov. PMID:15810436

Atomi, Haruyuki; Fukui, Toshiaki; Kanai, Tamotsu; Morikawa, Masaaki; Imanaka, Tadayuki

2004-01-01

58

Comprehensive Luciferase-Based Reporter Gene Assay Reveals Previously Masked Up-Regulatory Effects of miRNAs  

PubMed Central

MicroRNAs (miRNAs) are small non-coding RNAs that regulate the majority of the transcriptome at a post-transcriptional level. Because of this critical role, it is important to ensure that the assays used to determine their functionality are robust and reproducible. Typically, the reporter gene assay in cell-based systems has been the first-line method to study miRNA functionality. In order to overcome some of the potential errors in interpretation that can be associated with this assay, we have developed a detailed protocol for the luciferase reporter gene assay that has been modified for miRNAs. We demonstrate that normalization against the effect of the miRNA and cellular factors on the luciferase coding sequence is essential to obtain the specific impact of the miRNA on the 3'UTR (untranslated region) target. Our findings suggest that there is a real possibility that the roles for miRNA in transcriptome regulation may be misreported due to inaccurate normalization of experimental data and also that up-regulatory effects of miRNAs are not uncommon in cells. We propose to establish this comprehensive method as standard for miRNA luciferase reporter assays to avoid errors and misinterpretations in the functionality of miRNAs. PMID:25192285

Campos-Melo, Danae; Droppelmann, Cristian A.; Volkening, Kathryn; Strong, Michael J.

2014-01-01

59

41 CFR 102-84.55 - When are the Annual Real Property Inventory reports due?  

...2014-01-01 false When are the Annual Real Property Inventory reports due? 102-84.55 Section...102-84.55 When are the Annual Real Property Inventory reports due? You must prepare the Annual Real Property Inventory...

2014-01-01

60

41 CFR 102-84.55 - When are the Annual Real Property Inventory reports due?  

Code of Federal Regulations, 2012 CFR

...2012-01-01 false When are the Annual Real Property Inventory reports due? 102-84.55 Section...102-84.55 When are the Annual Real Property Inventory reports due? You must prepare the Annual Real Property Inventory...

2012-01-01

61

41 CFR 102-84.55 - When are the Annual Real Property Inventory reports due?  

Code of Federal Regulations, 2013 CFR

...2013-07-01 false When are the Annual Real Property Inventory reports due? 102-84.55 Section...102-84.55 When are the Annual Real Property Inventory reports due? You must prepare the Annual Real Property Inventory...

2013-07-01

62

Right subclavian vein catheterism complication due to a 'foreign body': a case report  

PubMed Central

Introduction Central venous access devices are widely used in hospital practice. Complications associated with their use are well described and reviewed. In this paper, we report a former complication that in turn created a new complication during a standardized procedure. Case presentation We report the case of an 81-year-old Caucasian woman requiring total parenteral nutrition due to a high-debt enterocutaneous fistula. In a previous right subclavian catheterization a fragmentation of the tip of the catheter, probably not recognized at the time, provoked an extrinsic compression of the vessel. Conclusion Fragmentation of a central venous catheter is a possible complication of catheterization and can be missed. Control of a catheter is imperative after its removal, even if not always practiced. PMID:20958959

2010-01-01

63

FBI Reports Drop in Crime Due to Gun Control  

NSDL National Science Digital Library

In a report released Sunday, the FBI found that a seven percent drop in homicides was entirely attributable to a decrease in killings committed with guns. The report also linked a drop in the rate of robbery involving guns to a ten percent drop in overall robberies nationwide. The decline in crime remained consistent in other categories as well, including property crimes, homicide against women, and random violent crimes. Surprisingly, in the wake of certain highly publicized acts of youth violence, the rate of violent juvenile crime has also dropped. This marks the seventh straight year that crime has declined in America. While both the report and many experts see a direct link between declining crime and tougher gun control, there continue to be dissenters -- one might ask if there isn't a certain circularity to the FBI's conclusions, and it remains to be seen if the current Congress will be swayed to retake up the gun legislation defeated this past summer.

Charbonneau, David D.

64

Diabetic Foot Due to Anaphylactic Shock: A Case Report  

PubMed Central

Introduction: Diabetic foot is a clinical disorder, which is commonly seen in patients with diabetes mellitus. It is also the major cause of below knee amputation in the world. There are many underlying causes such as neuropathic, ischemic, and infectious causes for diabetic foot. Local or systemic complications may develop after snake bite. Case Presentation: We reported a very rare case, involving a 78-year-old male admitted to the Emergency Department, who developed anaphylactic shock and diabetic foot after the snake bite. Conclusions: Reviewing the literature, this is the second reported case of snake bite associated with diabetic foot. PMID:25147776

Karakus, Ali; Ozkan, Mustafa; Karcioglu, Murat; Ozden, Raif; Ustun, Ihsan; Caliskan, Koca; Gokce, Cumali; Sahan, Mustafa

2014-01-01

65

Clinical characteristics, patient-reported outcomes, and previous therapeutic management of patients with uncontrolled neuropathic pain referred to pain clinics.  

PubMed

Background. The aim of this report was to evaluate the clinical profile and previous management of patients with uncontrolled neuropathic pain who were referred to pain clinics. Methods. We included adult patients with uncontrolled pain who had a score of ?4 in the DN4 questionnaire. In addition to sociodemographic and clinical data, we evaluated pain levels using a visual analog scale as well as anxiety, depression, sleep, disability, and treatment satisfaction employing validated tools. Results. A total of 755 patients were included in the study. The patients were predominantly referred to pain clinics by traumatologists (34.3%) and primary care physicians (16.7%). The most common diagnoses were radiculopathy (43%) and pain of oncological origin (14.3%). The major cause for uncontrolled pain was suboptimal treatment (88%). Fifty-three percent of the patients were depressed, 43% had clinical anxiety, 50% rated their overall health as bad or very bad, and 45% noted that their disease was severely or extremely interfering with their daily activities. Conclusions. Our results showed that uncontrolled neuropathic pain is a common phenomenon among the specialties that address these clinical entities and, regardless of its etiology, uncontrolled pain is associated with a dramatic impact on patient well-being. PMID:24891950

de Andrés, José; de la Calle, José-Luis; Pérez, María; López, Vanessa

2014-01-01

66

30 CFR 210.53 - When are my royalty reports and payments due?  

Code of Federal Regulations, 2010 CFR

...SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT FORMS AND REPORTS Royalty Reports-Oil, Gas, and Geothermal Resources § 210.53 When are my royalty reports and payments due? (a) Completed Forms MMS-2014 for royalty...

2010-07-01

67

Case report of bacteremia due to Neisseria mucosa.  

PubMed

Neisseria mucosa, a Gram-negative diplococcus, is part of normal nasopharyngeal flora. We report a case of bacteremia caused by N. mucosa in a 50-year-old neutropenic patient suffering from non-secretory multiple myeloma stage IIIA. This case underscores that mostly nonpathogenic N. mucosa can cause bacteremia in neutropenic patients who developed mucositis after hematopoietic stem cell transplantation. PMID:23905778

Mechergui, Arij; Achour, Wafa; Baaboura, Rekaya; Ouertani, Hela; Lakhal, Amal; Torjemane, Lamia; Othman, Tarek Ben; Hassen, Assia Ben

2014-04-01

68

Bacterial endocarditis due to Eikenella corrodens: a case report.  

PubMed

Of all the causes of bacterial endocarditis, HACEK group consisting of Haemophilus, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, and Kingella Kingae are rare causative agents. We report a case of bacterial endocarditis by E. corrodens, which is one of the members of the HACEK group. PMID:17643001

Mahapatra, A; Mishra, S; Pattnaik, D; Patnaik, K

2003-01-01

69

Peroneal Tendon Impingement due to Bulky Osteochondroma: A Case Report.  

PubMed

Osteochondromas are the most common benign bone tumors. Although many are asymptomatic, they can produce a mass effect impinging against soft tissues or interfering with joint function. The authors present a case report and review of literature of an ankle osteochondroma successfully treated by excision. PMID:25377502

São Simão, Ricardo; Moura, António Mendes; Sá Rodrigues, André; Pinto, Rui

2014-11-01

70

Cluster Report or Survey Description Date due to IEA Responsible person(s) Comments Summer Activity Report  

E-print Network

Cluster Report or Survey Description Date due to IEA Responsible person(s) Comments Summer Activity Report Activity reports for Summer, 2013 January 31, 2014 Academic Department Heads By December 13, 2013, data is provided by IEA for report completion. Fall Activity Report Activity reports for Fall, 2013

Fernandez, Eduardo

71

Spontaneous atraumatic vertebral artery occlusion due to physiological cervical extension: case report.  

PubMed

Vertebral artery (VA) occlusion is a serious and potentially life-threatening occurrence. Bow hunter's syndrome, a mechanical occlusion of the VA due to physiological head rotation, has been well described in the medical literature. However, mechanical VA compression due to routine flexion or extension of the neck has not been previously reported. The authors present the unique case of a woman without any history of trauma who had multiple posterior fossa strokes and was found to have dynamic occlusion of her right VA visualized via cerebral angiogram upon extension of her neck. This occlusion was attributed to instability at the occipitocervical junction in a patient with a previously unknown congenital fusion of both the occiput to C-1 and C-2 to C-3. An occiput to C-3 fusion was performed to stabilize her cervical spine and minimize the dynamic vascular compression. A postoperative angiogram showed no evidence of restricted flow with flexion or extension of the neck. This case emphasizes the importance of considering symptoms of vertebrobasilar insufficiency as a result of physiological head movement. The authors also review the literature on VA compression resulting from physiological head movement as well as strategies for clinical diagnosis and treatment. PMID:24438424

Safain, Mina G; Talan, Jordan; Malek, Adel M; Hwang, Steven W

2014-03-01

72

Eosinophilic Pleuritis due to Sparganum: A Case Report  

PubMed Central

Sparganosis is a rare parasitic disease caused by migrating plerocercoid tapeworm larva of the genus Spirometra. Infection in humans is mainly caused by the ingestion of raw or inadequately cooked flesh of infected frogs, snakes, and chickens. Here, we report a rare case of a 45-year-old man who was admitted to our hospital with left lower chest pain. The chest radiograph and computed tomography (CT) scan revealed localized pleural effusion in the left lower lobe; further, peripheral blood eosinophilia and eosinophilic pleural effusion were present. Percutaneous catheter drainage was performed, which revealed long worm-shaped material that was identified as a sparganum by DNA sequencing. The patient showed clinical improvement after drainage of the sparganum. This study demonstrates the importance of considering parasitic diseases in the differential diagnosis of eosinophilic pleural effusion. PMID:25352705

Oh, Youngmin; Kim, Jeong-Tae; Kim, Mi-Kyeong; Chang, You-Jin; Eom, Keeseon; Park, Jung-Gi; Lee, Ki-Man; Choe, Kang-Hyeon

2014-01-01

73

Contact blepharoconjunctivitis due to black henna--a case report.  

PubMed

Para-phenylenediamine (PPD) can induce immediate or - more often - delayed hypersensitivity. We report the case of 48-year old female admitted to the out-patient allergy clinic a day after her visit in a beauty parlour, where she had her eyelashes and eyebrows dyed with henna. Physical examination revealed prominent edema of the upper part of the face including forehead, cheeks and eyes causing severe narrowing of the palpebral chink. Skin prick tests (SPT) with common allergens were positive for Dermatophagoides pteronyssinus, Dermatophagoides farinae and moulds, while the SPT with PPD was negative. Patch test to PPD was positive. Further investigations revealed eosinophilia in the tear fluid. To our knowledge, this is the first case of PPD-induced contact blepharoconjunctivitis (CB) with concomitant increased eosinophilia in the tear fluid. PMID:22492286

Pas-Wyro?lak, Alicja; Wiszniewska, Marta; Kr?cisz, Beata; Swierczy?ska-Machura, Dominika; Pa?czy?ski, Cezary; Walusiak-Skorupa, Jolanta

2012-06-01

74

Allergic bronchopulmonary mycosis due to Alternaria: Case report and review.  

PubMed

While allergic bronchopulmonary aspergillosis and mycosis are well recognised, no cases have been described related to Alternaria spp. Alternaria is a common sensitising fungus in asthmatics and related to thunderstorm asthma. We report a case of an asthmatic who presented with worsening asthma control, mild eosinophilia on high dose inhaled corticosteroids (800 ?g/day), a total IgE of 3800 KIU/L, an Alternaria-specific IgE of 21.3 KUa/L and positive skin prick test, negative specific IgE and skin prick test to Aspergillus fumigatus, Penicillium spp., Cladosporium spp., Trichophyton spp. and a normal CT scan of the thorax. He responded well to a short course of oral prednisolone and then oral itraconazole, given over 17 months but relapsed 1 month after stopping it. PMID:24371728

Singh, Bhagteshwar; Denning, David W

2012-01-01

75

Acute abdomen due to primary omentitis: a case report  

PubMed Central

Background Idiopathic segmental infarction of the greater omentum (ISIGO) is an uncommon cause of acute abdomen in children and adults and its etiology is rather vague and speculative. The clinical presentation is usually with atypical acute or subacute abdominal pain. In a number of cases radiologic imaging allows proper preoperative diagnosis and treatment. Case presentation We report a case of ISIGO in a 31 year old patient, who presented with acute abdominal pain, nausea, vomiting and leukocytosis. Radiologic investigation was non-specific. The patient underwent surgical resection of the infracted omentum with compete recovery. Conclusion ISIGO should be considered in the differential of acute abdomen especially when presentation is atypical and all other causes have been excluded. In cases with non-specific radiologic findings, laparotomy is necessary for proper diagnosis and treatment. Surgical resection of the infracted omentum results in uneventful recovery in the majority of cases. PMID:17655767

Safioleas, Michael; Stamatakos, Michael; Giaslakiotis, Konstantinos; Smirnis, Anastasios; Safioleas, Panagiotis

2007-01-01

76

Endocarditis due to Corynebacterium pseudodiphtheriticum: five case reports, review, and antibiotic susceptibilities of nine strains.  

PubMed

Five cases of endocarditis due to Corynebacterium pseudodiphtheriticum are described. Two patients died, two patients with prosthetic valve endocarditis were successfully treated with antibiotics and valve replacement, and one patient with native valve endocarditis was successfully treated with penicillin alone. We also review 12 previously reported cases of C. pseudodiphtheriticum endocarditis. In vitro susceptibilities to 15 antibiotics were determined for nine isolates. The minimum inhibitory concentrations (MICs) of penicillin, amoxicillin, cefamandole, cephalexin, and rifampicin were all less than or equal to 0.12 mg/L. The MICs of vancomycin and ciprofloxacin for all strains were less than or equal to 0.5 mg/L. Tobramycin was the most active aminoglycoside, with MICs for all strains that were less than or equal to 0.12 mg/L. On the basis of in vitro data and the results of previous reports, penicillin alone or in combination with an aminoglycoside should achieve bacteriologic cure. Vancomycin should be used in patients who are allergic to penicillin. PMID:1962103

Morris, A; Guild, I

1991-01-01

77

Trigeminal Neuralgia due to an Isolated Cerebral Varix: Case Report  

PubMed Central

Intracranial isolated varix is a very rare entity. Although it is usually asymptomatic, there are reports on symptomatic cases with hemorrhage or mass effect that mostly relate to arteriovenous fistulas or arteriovenous malformations. We present an extremely rare case of trigeminal neuralgia caused by an isolated varix. A 55-year-old woman had been experiencing right trigeminal neuralgia for 3 years. Computed tomography and magnetic resonance imaging revealed an enhanced mass lesion on the root entry zone of the right trigeminal nerve. Angiograms confirmed the mass was a varix arising on the vein connecting the basal vein of Rosenthal and the superior petrosal vein. Preoperative three-dimensional (3D) imaging clearly depicted the anatomical relation of the varix, adjacent vessels, and trigeminal nerve, which helped plan operative procedures. The varix with its parent vein was successfully transposed from the nerve without sacrificing any veins. Her pain disappeared immediately after the surgery and did not recur during a 30-month follow-up period. The 3D image contributed to making an accurate and safer operative plan especially for this rare case. PMID:25485214

Inoue, Takuro; Shima, Ayako; Hirai, Hisao; Suzuki, Fumio; Matsuda, Masayuki

2014-01-01

78

[Leg ulcer due to hydroxyurea. A case report].  

PubMed

Hydroxyurea is an antineoplasic agent usually used in myeloproliferative syndromes, but also in other benign pathological circumstances. Several dermatological manifestations have been recognized as being secondary to its prolonged use, of which the leg ulcer. We report an observation. Mrs. L.D, 47 years, were hospitalized on July 14, 2004 for an ulcer of left ankle in a feverish context. She was followed since 2001 for a chronic myelogenous leukaemia, and took hydroxyurea at a rate of 1500 mg per day, with a good clinical and hematologic answer. She presented a painful ulcer compared to the left external malleolus, with purulent bottom, without signs of vascular attack. The hemogram showed a hyperleucocytosis with 24.000 white elements/mm3 with neutrophilic polynucleosis. Pus sample on the ulcer showed Pseudomonas aeruginosa, and the blood culture was negative. The cure was obtained two months after stopping hydroxyurea. The ulcer of leg related to hydroxyurea is a seldom described pathology. Its occurrence imposes the final stop of the treatment. PMID:17632983

Gning, S B; Debonne, J M; Diagne-Guèye, N M; Ndiaye, B; Fall, F; Mbaye, P S

2006-01-01

79

Otomycosis due to Aspergillus spp. in a dog: case report and literature review.  

PubMed

This report describes the clinical findings, clinicopathology and treatment of otomycosis caused by Aspergillus spp. in an atopic dog affected by chronic unilateral purulent otitis externa unresponsive to topical and oral antibiotics and antifungal treatments. Cytology of otic exudate revealed neutrophils and septate fungal hyphae, and otic culture grew Aspergillus spp. and no bacteria. Treatments included allergen-specific immunotherapy, topical and oral antifungal therapy and anti-inflammatory steroid therapy. Final resolution occurred after treatment of the underlying hypersensitivity disorder, administration of topical ketoconazole and debridement of infectious ear exudate. Otomycosis due to filamentous fungi may, as in humans, occur in dogs with ear canals compromised by pre-existing allergic or bacterial otitis, and possibly previous antibiotic therapy. Antifungal medications provided clinical improvement, but the key to successful treatment was the restoration of the normal physiology of the external auditory canal. PMID:20492628

Coyner, Kimberly

2010-12-01

80

Osmotic shock tolerance and membrane fluidity of cold-adapted Cryptococcus flavescens OH 182.9, previously reported as Cr. nodaensis, a biocontrol agent of Fusarium head blight  

Technology Transfer Automated Retrieval System (TEKTRAN)

Cryptococcus nodaensis (previously reported as Cr. nodaensis), a biological control agent of Fusarium head blight, has been previously shown to have improved desiccation tolerance after cold adaptation. The goal of the current study was to determine the effect of cold adaptation on the physicochemi...

81

Study by University of Maryland finds that US cervical cancer rates are higher than previously reported, especially among older women  

Cancer.gov

Cervical cancer rates in the United States are higher than previously believed, particularly among 65- to 69-year-old women and African-American women, according to a study led by a researcher at the University of Maryland School of Medicine.

82

Stereotactic radiotherapy for spinal intradural metastases developing within or adjacent to the previous irradiation field--report of three cases.  

PubMed

Results of stereotactic radiotherapy (SRT) for spinal intradural metastases developing inside or adjacent to the previous external-beam radiation therapy (EBRT) field are shown in 3 cases. One case of spinal intramedullary metastasis and two cases of intradural extramedullary metastases were treated using a Novalis shaped-beam SRT. Case 1 developed an intramedullary metastatic tumor in the C1 spinal medulla inside the previous whole brain EBRT field and another lesion adjacent to the field in the C2 spinal medulla. Case 2 developed intradural extramedullary metastasis around C6-8 inside the previous EBRT field for the primary lung adenocarcinoma. Case 3 developed multiple spinal intradural extramedullary metastatic deposits after surgical resection and following whole brain EBRT for brain metastasis. We delivered 24 to 36 Gy in 5 to 12 fractions. The treated tumors were stable or decreased in size until the patients' death from the primary cancer (10, 22, and 5 months). Neurological symptoms were stable or improved in all 3 patients. Palliative SRT using Novalis is expected to be safe and effective even if the patient develops spinal intradural metastases within or adjacent to the previous irradiation field. PMID:24640183

Mori, Yoshimasa; Hashizume, Chisa; Shibamoto, Yuta; Kobayashi, Tatsuya; Nakazawa, Hisato; Hagiwara, Masahiro; Tsugawa, Takahiko

2013-08-01

83

A previously-untranslated report by Freud of a lecture on the mechanism of obsessional ideas and phobias.  

PubMed

This is an English translation of Freud's report of a lecture that he delivered in 1895 on the 'Mechanism of obsessional ideas and phobias'. The report was not included in the Standard Edition of Freud's psychological works, and nor was it included in any of the other collections of his writings. The lecture described in this report seems to have been derived directly from Freud's contemporaneous essay on 'Obsessions and phobias' (1895b). However there are a few discrepancies between the two, and these are discussed in the footnotes to the translation. PMID:2737834

Solms, M

1989-01-01

84

Secondary Knee Osteoarthritis due to Neurofibromatosis Type 1 Treated with above the Knee Amputation: A Case Report.  

PubMed

Background. Neurofibromatosis Type 1 (NF-1) has a variety of associated orthopaedic manifestations that have been previously reported. We report a case of severe, grade 4 knee osteoarthritis (OA) with recurrent subluxation and joint laxity due to multiple extra-articular neurofibromas ultimately treated with Above the Knee Amputation (AKA). Case Description. A 39-year-old man presented with multiple neurofibromas and lymphedema leading to degenerative changes of the knee. Conservative treatment failed due to the severity of the knee degeneration and patient discomfort. Likewise, arthroplasty was not possible due to poor bone quality and joint instability. Therefore, AKA was selected to relieve symptoms and provide functional improvement. six months after the procedure the patient has increased functional capacity for ambulation and activities of daily living, as well as significant decrease in pain and discomfort. Clinical Relevance. Extra-articular neurofibromas causing severe secondary OA in relatively young patients can be functionally improved with AKA and prosthetic device use. PMID:23936704

Patel, Jay; Whiting, Jeffrey; Jones, Daniel

2013-01-01

85

12 CFR 1010.558 - Previously accepted state filings-notice of revocation rights on property report cover page.  

Code of Federal Regulations, 2012 CFR

...pursuant to § 1010.552 shall be prepared in accordance with § 1010.105 and shall include the paragraphs set forth in section XXX of the appendix to this part: Language to be Included on Property Report Cover Page. (2) If the purchaser is...

2012-01-01

86

12 CFR 1010.558 - Previously accepted state filings-notice of revocation rights on property report cover page.  

Code of Federal Regulations, 2013 CFR

...pursuant to § 1010.552 shall be prepared in accordance with § 1010.105 and shall include the paragraphs set forth in section XXX of the appendix to this part: Language to be Included on Property Report Cover Page. (2) If the purchaser is...

2013-01-01

87

12 CFR 1010.558 - Previously accepted state filings-notice of revocation rights on property report cover page.  

...pursuant to § 1010.552 shall be prepared in accordance with § 1010.105 and shall include the paragraphs set forth in section XXX of the appendix to this part: Language to be Included on Property Report Cover Page. (2) If the purchaser is...

2014-01-01

88

Leptotrichia endocarditis: report of two cases from the International Collaboration on Endocarditis (ICE) database and review of previous cases.  

PubMed

Leptotrichia species typically colonize the oral cavity and genitourinary tract. We report the first two cases of endocarditis secondary to L. goodfellowii sp. nov. Both cases were identified using 16S rRNA gene sequencing. Review of the English literature revealed only two other cases of Leptotrichia sp. endocarditis. PMID:17960435

Caram, L B; Linefsky, J P; Read, K M; Murdoch, D R; Lalani, T; Woods, C W; Reller, L B; Kanj, S S; Premru, M M; Ryan, S; Al-Hegelan, M; Donnio, P Y; Orezzi, C; Paiva, M G; Tribouilloy, C; Watkin, R; Harris, O; Eisen, D P; Corey, G R; Cabell, C H; Petti, C A

2008-02-01

89

Analysis of Over 10,000 Cases Finds No Association between Previously-Reported Candidate Polymorphisms and Ovarian Cancer Outcome  

PubMed Central

Background Ovarian cancer is a leading cause of cancer-related death among women. In an effort to understand contributors to disease outcome, we evaluated single-nucleotide polymorphisms (SNPs) previously associated with ovarian cancer recurrence or survival, specifically in angiogenesis, inflammation, mitosis, and drug disposition genes. Methods Twenty-seven SNPs in VHL, HGF, IL18, PRKACB, ABCB1, CYP2C8, ERCC2, and ERCC1 previously associated with ovarian cancer outcome were genotyped in 10,084 invasive cases from 28 studies from the Ovarian Cancer Association Consortium with over 37,000 observed person-years and 4,478 deaths. Cox proportional hazards models were used to examine the association between candidate SNPs and ovarian cancer recurrence or survival with and without adjustment for key covariates. Results We observed no association between genotype and ovarian cancer recurrence or survival for any of the SNPs examined. Conclusions These results refute prior associations between these SNPs and ovarian cancer outcome and underscore the importance of maximally powered genetic association studies. Impact These variants should not be used in prognostic models. Alternate approaches to uncovering inherited prognostic factors, if they exist, are needed. PMID:23513043

White, Kristin L.; Vierkant, Robert A.; Fogarty, Zachary C.; Charbonneau, Bridget; Block, Matthew S.; Pharoah, Paul D.P.; Chenevix-Trench, Georgia; Rossing, Mary Anne; Cramer, Daniel W.; Pearce, C. Leigh; Schildkraut, Joellen M.; Menon, Usha; Kjaer, Susanne Kruger; Levine, Douglas A.; Gronwald, Jacek; Culver, Hoda Anton; Whittemore, Alice S.; Karlan, Beth Y.; Lambrechts, Diether; Wentzensen, Nicolas; Kupryjanczyk, Jolanta; Chang-Claude, Jenny; Bandera, Elisa V.; Hogdall, Estrid; Heitz, Florian; Kaye, Stanley B.; Fasching, Peter A.; Campbell, Ian; Goodman, Marc T.; Pejovic, Tanja; Bean, Yukie; Lurie, Galina; Eccles, Diana; Hein, Alexander; Beckmann, Matthias W.; Ekici, Arif B.; Paul, James; Brown, Robert; Flanagan, James; Harter, Philipp; du Bois, Andreas; Schwaab, Ira; Hogdall, Claus K.; Lundvall, Lene; Olson, Sara H.; Orlow, Irene; Paddock, Lisa E.; Rudolph, Anja; Eilber, Ursula; Dansonka-Mieszkowska, Agnieszka; Rzepecka, Iwona K.; Ziolkowska-Seta, Izabela; Brinton, Louise; Yang, Hannah; Garcia-Closas, Montserrat; Despierre, Evelyn; Lambrechts, Sandrina; Vergote, Ignace; Walsh, Christine; Lester, Jenny; Sieh, Weiva; McGuire, Valerie; Rothstein, Joseph H.; Ziogas, Argyrios; Lubi?ski, Jan; Cybulski, Cezary; Menkiszak, Janusz; Jensen, Allan; Gayther, Simon A.; Ramus, Susan J.; Gentry-Maharaj, Aleksandra; Berchuck, Andrew; Wu, Anna H.; Pike, Malcolm C.; Van Den Berg, David; Terry, Kathryn L.; Vitonis, Allison F.; Doherty, Jennifer A.; Johnatty, Sharon; deFazio, Anna; Song, Honglin; Tyrer, Jonathan; Sellers, Thomas A.; Phelan, Catherine M.; Kalli, Kimberly R.; Cunningham, Julie M.; Fridley, Brooke L.; Goode, Ellen L.

2013-01-01

90

A case report of huge perirenal liposarcoma associated with renal cell carcinoma and reviews of three previous cases.  

PubMed

Retroperitoneal liposarcoma (RPLS) is a rare malignant tumor yet with a high recurrence rate. It is mostly observed in limbs and during retroperitoneal clearance, and accounts for nearly 40% of all adult retroperitoneal soft tissue sarcomas [1]. Renal cell carcinoma (RCC) is a common cancer developed in urinary system and its occurrence rate accounts for 3% of whole body malignant tumors [2]. In this report, we present a case of large perirenal liposarcoma associated with RCC, which is to date the fourth identified case. We analyzed the clinical pathologic data of this patient and reviewed the other three cases. Compared to the other cases, this patient is diagnosed at the youngest age and the liposarcoma tumor is with the largest diameter. Moreover, we have been following up the patient after operation for the longest time. All of these made this report rare and important. PMID:25550981

Liu, Zhe; Xu, Yuanhong; Long, Jin; Guo, Kejian; Du, Ruixia

2014-01-01

91

A case report of huge perirenal liposarcoma associated with renal cell carcinoma and reviews of three previous cases  

PubMed Central

Retroperitoneal liposarcoma (RPLS) is a rare malignant tumor yet with a high recurrence rate. It is mostly observed in limbs and during retroperitoneal clearance, and accounts for nearly 40% of all adult retroperitoneal soft tissue sarcomas [1]. Renal cell carcinoma (RCC) is a common cancer developed in urinary system and its occurrence rate accounts for 3% of whole body malignant tumors [2]. In this report, we present a case of large perirenal liposarcoma associated with RCC, which is to date the fourth identified case. We analyzed the clinical pathologic data of this patient and reviewed the other three cases. Compared to the other cases, this patient is diagnosed at the youngest age and the liposarcoma tumor is with the largest diameter. Moreover, we have been following up the patient after operation for the longest time. All of these made this report rare and important.

Liu, Zhe; Xu, Yuanhong; Long, Jin; Guo, Kejian; Du, Ruixia

2014-01-01

92

The use of ultrasound to facilitate spinal anesthesia in a patient with previous lumbar laminectomy and fusion: a case report.  

PubMed

We describe a case of ultrasound (US)-facilitated spinal anesthesia in a patient with a prior lumbar laminectomy and spinal fusion who presented for total knee arthroplasty. Traditional, landmark-guided spinal anesthesia had previously failed. Although pre-procedural US identified a soft-tissue window at L3/4, a 25G pencilpoint needle encountered resistance. Reassured from US imaging that this was not bone, we used a 22G cutting tip needle successfully. We believe spinal anesthesia would not have been possible in this patient without US, adding to the evidence that US-facilitated neuraxial anesthesia is useful, particularly in technically difficult, if not 'impossible,' cases. PMID:19455701

Chin, Ki Jinn; Macfarlane, Alan J R; Chan, Vincent; Brull, Richard

2009-10-01

93

An Experience with Managing Cancer Patients Reportedly Previously Informed of the Absence of Additional Available Antineoplastic Therapeutic Options  

PubMed Central

Over the past 5 years, a small group of cancer patients who stated their physicians had determined there were no additional available antineoplastic therapeutic options (including potential investigational strategies) were seen for a ‘second opinion’ in a cancer hospital-based oncology program and subsequently experienced what can reasonably be characterized as having achieved meaningful ‘clinical benefit’ (functioning at a fairly high level for a minimum 1 year in the work, home, and/or family environments) following the further delivery of a variety of treatment approaches. While recognized to be limited (or even simply ‘anecdotal’), this experience emphasizes several clinically relevant conclusions, including the overall utility of a ‘second-opinion’ strategy and the potential that the reported statement of an individual practitioner or cancer program that all rational options have been attempted may be inaccurate. PMID:25408656

River, George; Moore, Stephanie; Tucker, Jennifer; Markman, Maurie

2014-01-01

94

Salvage pancreaticoduodenectomy after complete response to chemoradiotherapy for a previously unresectable pancreatic adenosquamous carcinoma: a case report.  

PubMed

Pancreatic cancer is known for its typically late presentation and poor survival rates, with overall 5-year survival of less than 5%. The role of chemotherapy alone or with radiotherapy in the management of locally advanced tumors continues to be an area of debate.We report a case of locally advanced, pancreatic adenosquamous carcinoma that was initially deemed unresectable intraoperatively. Nonetheless, the tumor was resected after radiological response to gemcitabine-capecitabine chemoradiotherapy regimen similar to the Selective Chemoradiation in Advanced LOcalised Pancreatic cancer trial. Histological examination revealed complete pathological response with extensive fibrosis (ypT0 N0). On 12-month follow-up CT, a single liver lesion in the left lateral segment was identified and confirmed to be a metastasis with cytological diagnosis via EUS and FNA. The disease remained stable and confined to the solitary hepatic metastasis after further gemcitabine chemotherapy. Therefore, a further successful resection was performed.The 2 main strategies for the management of locally advanced unresectable pancreatic cancer are chemotherapy induction followed by consolidation chemoradiotherapy or chemotherapy alone, with conflicting published evidence. Evidence for the optimal management of the rare histological type of adenosquamous carcinoma is scant. We present a case of such tumor with a complete pathological response to chemoradiotherapy. The results of future studies in the area are eagerly awaited. PMID:25674740

Elias, Anne; Chatzizacharias, Nikolaos A; Xanthis, Athanasios; Corrie, Pippa; Davies, Susan; Brais, Rebecca J; Jamieson, Neville V; Praseedom, Raaj K; Huguet, Emmanuel; Harper, Simon J F; Jah, Asif

2015-02-01

95

Epithelioid trophoblastic tumor after induced abortion with previous broad choriocarcinoma: a case report and review of literature  

PubMed Central

Epithelioid trophoblastic tumor (ETT) is a rare trophoblastic tumor originating from chorionic-type intermediate trophoblasts (ITs). It is usually associated with a prior gestational event. We present a 44-year-old woman who had unusual pregnancy related history. The patient received her second spontaneous abortion at the age of 25 years and had suffered from choriocarcinoma in left board ligament at the age of 29 years. She admitted no more treatment after 3 courses of multiagent chemotherapy when serum ?-hCG returned to normal. Then she had Full-term delivery, induced abortion at the ages of 32, 33 years. The patient had high serum levels of beta-human chorionic gonadotropin (6587 IU/L). Microscopically, the tumor was composed of mainly mononuclear tumor cells, grew in cords, nests, and sheets within which were aggregates of hyaline material. Most were with distinct cell borders, eosinophilic cytoplasm. Immunohistochemical staining revealed strong diffuse reactivity for cytokeratins (AE1/AE3, CK18), P63, focal reactivity for beta-human chorionic gonadotropin, human placental lactogen, and inhibin-alpha. The Ki-67 index was 77%. The histological and immunohistochemical features were characteristic of epithelioid trophoblastic tumor. This is the first reported case of these two gestational trophoblastic tumor happened on one person with the intervening normal pregnancy. PMID:25550880

Zhang, Xiaofei; Shi, Haiyan; Chen, Xiaoduan

2014-01-01

96

Invasive Candidiasis due to Candida Norvegensis in a Liver Transplant Patient: Case Report and Literature Review.  

PubMed

Candida norvegensis is an emerging fluconazole-resistant pathogen isolated in most cases from skin and mucous membranes of immunocompromized patients. Documented invasive candidiasis (IC) due to C. norvegensis has been rarely reported, thus the clinical features of patients at risk for this pathogen are poorly defined. We report a liver transplant patient who developed IC due to C. norvegensis and review other cases of C. norvegensis IC published in the literature. PMID:25002960

Musso, Maria; Giannella, Maddalena; Antonini, Mario; Bordi, Eugenio; Ettorre, Giuseppe Maria; Tessitore, Loretta; Mariano, Andrea; Capone, Alessandro

2014-05-13

97

Invasive Candidiasis due to Candida Norvegensis in a Liver Transplant Patient: Case Report and Literature Review  

PubMed Central

Candida norvegensis is an emerging fluconazole-resistant pathogen isolated in most cases from skin and mucous membranes of immunocompromized patients. Documented invasive candidiasis (IC) due to C. norvegensis has been rarely reported, thus the clinical features of patients at risk for this pathogen are poorly defined. We report a liver transplant patient who developed IC due to C. norvegensis and review other cases of C. norvegensis IC published in the literature. PMID:25002960

Musso, Maria; Giannella, Maddalena; Antonini, Mario; Bordi, Eugenio; Ettorre, Giuseppe Maria; Tessitore, Loretta; Mariano, Andrea; Capone, Alessandro

2014-01-01

98

Acute renal failure due to rhabdomyolysis following dengue viral infection: a case report  

PubMed Central

Introduction With more than one-third of the world’s population living in areas at risk for transmission, dengue fever is a leading cause of illness and death in the tropics and subtropics. Despite the high incidence of dengue fever, rhabdomyolysis leading to acute renal failure is an extremely rare complication of dengue fever. Only a few such cases have been reported in the literature. Case presentation We describe the case of a 42-year-old, previously healthy Sri Lankan Sinhalese man who developed acute renal failure due to rhabdomyolysis following dengue virus infection. He was transferred to our institution with a five-day history of fever, headache, myalgia, impaired level of consciousness, and reduced urinary output. He was hemodynamically stable and did not have evidence of plasma leakage. His serology for dengue immunoglobulin M and immunoglobulin G was positive, and biochemical investigations disclosed evidence of rhabdomyolysis and acute renal failure. He was treated with induced alkaline diuresis and hemodialysis, and he experienced an uncomplicated recovery. Conclusion The occurrence of acute renal failure significantly increases the mortality of patients with dengue fever. Therefore, early diagnosis and early management are crucial in rhabdomyolysis complicating dengue fever to prevent established acute renal failure. It should be kept in mind that the threshold for suspecting rhabdomyolysis is very low in dengue fever. Creatinine phosphokinase levels should routinely be measured in all patients with severe dengue fever for early detection of rhabdomyolysis to prevent acute renal failure. PMID:23889764

2013-01-01

99

Welcome to the latest issue of Harvard Medicine News, a weekly electronic publication that will continue to chronicle the extraordinary world of HMS, previously reported in Focus. [More  

E-print Network

Welcome to the latest issue of Harvard Medicine News, a weekly electronic publication that will continue to chronicle the extraordinary world of HMS, previously reported in Focus. [More] To read all news. MORE » A Sharper Tool for Genome Engineering New method for editing genomes may be faster, safer

Raychaudhuri, Soumya

100

Vaccine risk assessment in children with a referred reaction to a previous vaccine dose: 2009–2011 retrospective report at the Bambino Gesu’ children hospital, Rome, Italy  

PubMed Central

Background During the last century, mass vaccination programs have achieved considerable success across the world in immunizing against several serious infectious diseases. However, vaccinations are threatened by their own success after results have been obtained: the more the incidence of potentially devastating diseases decreases, thanks to the success of vaccination programs, the more public attention shifts towards real or alleged “side effects” of vaccines. Methods We analyze the experience of 153 children with “reaction to a previous vaccine dose” continuing the vaccination protocol in the safe environment of the Center for risk vaccination at the Bambino Gesù Children’s Hospital IRCCS in Rome, from 2009 to 2011. Results To assess the suitability for vaccination, a specialized pre-vaccination advice and a skin prick test (SPT) was undergone, according to Wood’s guideline; 151 children were SPT negative and full vaccine was administered. Of the 153 children examined just 13 had symptoms suggestive of IgE-mediated reaction-type reactions with angioedema manifestations. Among them, 2 had positive STP, which required alternative measures of administration of the vaccine. No cases of post vaccination reaction was reported and no vaccination program was stopped due to a severe reaction. Conclusions Inadequate levels of immunization against infectious diseases remain a significant problem for public health. However, the reasons for incomplete vaccination and non-adoption of vaccination services are manifold. To maintain public confidence in vaccines, advanced immunization programs must include activities for monitoring the safety of the vaccine at the individual level and pursuing specialized counseling pre-and post-vaccination for those at risk. Our results underlined a gap between true and referred adverse reactions and are consistent with vaccine safety. Anyway, a continuous assessment of the risks and benefits of vaccination is required and the results must be disclosed in order to strengthen confidence in the existing and in the new immunization programs. PMID:24684865

2014-01-01

101

Pulmonary infection due to Pseudozyma aphidis in a patient with Burkitt lymphoma: first case report.  

PubMed

Fungal infections are being increasingly reported in patients with malignancies. Pseudozyma aphidis is an opportunistic yeast usually isolated from plants and rarely from human samples. In this study, we report the first case of pulmonary infection due to P. aphidis in a Burkitt lymphoma patient. PMID:23182077

Parahym, Ana Maria Rabelo de Carvalho; da Silva, Carolina Maria; Domingos, Igor de Farias; Gonçalves, Sarah Santos; Rodrigues, Márcia de Melo; de Morais, Vera Lúcia Lins; Neves, Rejane Pereira

2013-01-01

102

EOSINOPHILIC MENINGOENCEPHALITIS DUE TO TOXOCARA CANIS: CASE REPORT AND REVIEW OF THE LITERATURE  

Microsoft Academic Search

Toxocariasis is usually manifested as visceral larva migrans. Nervous system involvement is a rare com- plication. In this report, we describe one case of meningoencephalitis du et oToxocara canis and review the literature. We report a previously healthy two-year-old boy who was admitted after 24 hours of severe neurologic symptoms with marked eosinophilic pleocytosis in the cerebrospinal fluid and a

JOSE E. VIDAL; JAQUES SZTAJNBOK; ANTONIO CARLOS SEGURO

103

Severe Mitral Regurgitation due to Traumatic Anterolateral Papillary Muscle Rupture: A Case Report  

PubMed Central

A 29-year-old man was admitted for abrupt dyspnea and hemoptysis. An echocardiogram revealed severe mitral regurgitation due to papillary muscle rupture for which an emergency mitral valve replacement operation was performed 4 days after admission. Herein, we report our experience with this case along with a review of the literature. PMID:23275923

Lee, Chul Ho; Lee, Sub; Jang, Jae Seok

2012-01-01

104

Unique fatality due to claw injuries in a tiger attack: a case report.  

PubMed

This paper describes a unique case of a fatal tiger attack in the wild. In the present case, a tiger fatally mauled a 34-year-old female with its claws, instead of the usual mechanism of killing by the bite injury to the neck. The autopsy revealed multiple fatal and non-fatal injuries caused by the tiger claws. The characteristic injuries due to the tooth impacts were absent as the teeth of the offending tiger were either fallen or non-functional. To the best of our knowledge, probably this rare case would be the first reported human fatality due to the tiger claw injuries in the world. The purpose of the present article is to highlight the fatal injuries due to the tiger claws, as the claw-induced fatal injuries in a tiger attack are not reported in the medico-legal literature. Moreover, this report would be an illustrative one for differentiation between the fatal injuries due to the claws and tooth impacts in a tiger attack. Furthermore, the present report establishes the importance of the tiger claws as a source of fatal injuries in a tiger attack. PMID:25082732

Pathak, Hrishikesh; Dixit, Pradeep; Dhawane, Shailendra; Meshram, Satin; Shrigiriwar, Manish; Dingre, Niraj

2014-11-01

105

Native valve endocarditis due to Pseudallescheria boydii in a patient with AIDS: case report and review.  

PubMed

A 53-year-old man with AIDS developed mitral valve endocarditis due to infection with the fungus Pseudallescheria boydii. A limited number of cases of prosthetic valve endocarditis caused by this organism have been described. We report a unique case of pseudallescheria infection of a native valve and describe this disease in a patient with AIDS. PMID:2267494

Raffanti, S P; Fyfe, B; Carreiro, S; Sharp, S E; Hyma, B A; Ratzan, K R

1990-01-01

106

Operation Sun Beam, Shot Small Boy. Project Officer's report - Project 6. 9. Correlation of present and previous electric-field measurements  

SciTech Connect

On most previous nuclear detonations, signatures and quantitative measurements of the electric-field signals associated with the detonations was obtained at distances such that normal radiation field characteristics apply. On Small Boy, measurements were made from stations located much closer in, such as to be inside, on the boundary of and just outside the limits of the ionized sphere created by the nuclear burst. The electric-field characteristics in these regions were unknown. In the hope of providing continuity from the region of the unknown into the reasonably well-understood region of the radiation field, this project was requested to make the typical radiation-field type of measurement that had been made on previous detonations. This report covers the signature characteristics and quantitative measurements of the electric-field signal from Small Boy as seen from outside the immediate region of theoretical generating mechanism.

Reno; Fowles, H.M.

1985-09-01

107

Intussusception due to rectal adenocarcinoma in a young adult: A case report  

PubMed Central

An intussusception due to colonic adenocarcinoma has sometimes been reported. However, to the best of our knowledge, reports of intussusception due to rectal adenocarcinoma are extremely rare. In this report, the case of a young man with rectal adenocarcinoma causing intussusception is described. A 24-year-old man visited a hospital complaining of abdominal pain, and an upper rectal cancer was diagnosed by colonoscopy. Computed tomography showed intussusception caused by a large tumor in the pelvis and absence of distant metastases. Locally advanced rectal cancer causing intussusception was diagnosed, and a low anterior resection was performed. Intraoperatively, repair of the invagination could not be accomplished easily; therefore, the repair was abandoned. Instead, the tumor was removed en bloc to avoid dissemination of the cancer. Histopathologically, the tumor was diagnosed as a poorly differentiated adenocarcinoma, pStage IIA. The patient has no evidence of recurrence at 10 mo after the operation. PMID:25253975

Inada, Ryo; Nagasaka, Takeshi; Toshima, Toshiaki; Mori, Yoshiko; Kondo, Yoshitaka; Kishimoto, Hiroyuki; Fujiwara, Toshiyoshi

2014-01-01

108

Suicide case due to phosphoric acid ingestion: case report and review of literature.  

PubMed

Ingesting caustic substances represents a common event which may result in serious injuries of the gastrointestinal system. Severity of injury depends on the type of ingested substance: Caustic burns are more frequently associated with acid ingestion and their severity depends on type, concentration, time of exposure, and amount of the ingested substance. We report a case of phosphoric acid ingestion leading to death in a patient with depressive disorder. While reports ingestion of other acids and organophosphates can be found in the literature, there are no reports detailing a death due to phosphoric acid ingestion. We hope that presenting the findings in this case can aid death investigators in future cases that may involve ingestion of such a substance. After autopsy pH, phosphate and calcium ions concentration in the blood were analyzed. The cause of death was due to systemic effects: metabolic acidosis, hypophosphatemia, hypocalcemia, and hyperkalemia. PMID:25331575

Aquila, Isabella; Pepe, Francesca; Di Nunzio, Ciro; Ausania, Francesco; Serra, Arianna; Ricci, Pietrantonio

2014-11-01

109

Meningitis due to Fusobacterium necrophorum subspecies necrophorum . Case report and review of the literature  

Microsoft Academic Search

Summary This paper reports a case of fatal meningitis caused byFusobacterium necrophorum subsp.necrophorum in a previously healthy five-year-old child. The organism was isolated in pure culture from the cerebrospinal fluid and from intracranial pus obtained at autopsy. The role ofF. necrophorum in the development of meningitis is reaffirmed and its isolation and identification are discussed. The clinical presentation of the

J. A. Jacobs; E. E. Stobberingh; J. J. E. Hendriks; G. D. Vos; A. M. van der Wurff; G. Freling; D. M. M. Verschure

1993-01-01

110

Fatal encephalitis due to BK virus in a patient with common variable immunodeficiency: a case report.  

PubMed

Encephalitis due to BK virus is a rare condition. Here, we describe a young male patient with common variable immunodeficiency who developed fatal encephalitis due to BK virus. The patient presented initially with ocular symptoms that were followed by behavioral changes and spastic quadriparesis. Diagnosis was made by the compatible clinical findings and detection of viral DNA by polymerase chain reaction in the cerebrospinal fluid. To the best of our knowledge, this is the first report of BK virus encephalitis in a patient with common variable immunodeficiency. We suggest that BK virus should be suspected in cases of encephalitis; particularly in patients with immunodeficiency. PMID:23731846

Bakri, Faris G; Bahou, Yacoub G; Al-Sammarrai, Firas A; Hadidy, Azmy; Gharaibeh, Almutez; Zaid, Ghida K; Mahafzah, Azmi; Samara, Osama A; Ababneh, Nidaa A; Zak, Imad

2013-08-01

111

[A case report of aortoesophageal fistula due to thoracoabdominal aortic aneurysm].  

PubMed

Aortoesophageal fistulas due to thoracic aneurysms are usually fatal, with few reported survivors. A 57-year-old man with aortoesophageal fistula due to thoracoabdominal aortic aneurysm underwent the graft replacement of thoracoabdominal aorta. In the postoperative course, prosthetic graft infection had occurred in the result of residual esophageal fistula. On the 32nd postoperative day (POD), a subtotal esophagectomy was performed and the esophagus was reconstructed by gastrointestinal interposition technique via a retrosternal route. Following the second operative procedure, inflammatory reactions had been improved with systemic administration of antibiotics and continuous irrigation of the infected cavity. On 77th POD, he was discharged. PMID:9513530

Nakayama, S; Minami, K; Sakaguchi, G; Tsuneyoshi, H

1998-01-01

112

Auricle injury due to human bite - A rare case report and review literature.  

PubMed

Traumatic auricular amputation due to human bite is not a common event. Bite wounds are always considered to be complex injuries contaminated with unique poly-microbial inoculum. Human bites are as serious as animal bites because they induce a higher incidence of infectious complications. In bite wounds to the face, infectious complications can create more difficulties than the initial tissue damage itself for the task of restoring an esthetic appearance. In this case report a young male patient had ear lobule injury on interpersonal violence and amputation of ear lobule results. Due to delay in presentation and high chances of infection wound healing by secondary intention achieved. PMID:25485846

Sinwar, Prabhu Dayal

2015-01-01

113

Cerebral Phaeohyphomycosis due to Cladophialophora bantiana – A Case Report and Review of Literature from India  

PubMed Central

Cerebral phaeohyphomycosis is a rare disease caused by dematiaceous fungi. It has poor prognosis irrespective of the immune status of the patient. Cladophialophora bantiana is the most commonly isolated species. We report a case of multiple brain abscesses caused by C. bantiana in an immune competent patient. The diagnosis was based on CT scan of head, direct examination and culture of the aspirate from the abscess. Despite complete surgical resection of the abscesses and antifungal therapy with amphotericin B and voriconazole the patient could not be saved. All the cases of cerebral phaeohyphomycosis due to this rare neurotropic fungus reported from India between 1962 and 2009 have also been reviewed. PMID:24959445

Chhina, Deepinder Kaur; Kaushal, Vandana; Kaushal, Rakesh Kumar; Singh, Jasdeep

2014-01-01

114

Diplopia due to Dacryops  

PubMed Central

Dacryops is a lacrimal ductal cyst. It is known that it can cause globe displacement, motility restriction, and proptosis because of the mass effect. Diplopia due to dacryops has not been reported previously. Here, we present a 57-year-old man with binocular horizontal diplopia that occurred during left direction gaze due to dacryops. PMID:24368956

Duman, Re?at; Balc?, Mehmet

2013-01-01

115

Isolated shoulder palsy due to cortical infarction: a case report and literature review of clinicoradiological correlations.  

PubMed

Clinicoradiological correlations observed in patients with small cortical infarctions have supported somatotopic representation of different parts of body areas in primary motor cortex. However, isolated shoulder weakness because of infarction in precentral gyrus has rarely been described. We report an 80-year-old woman with isolated shoulder palsy because of cortical ischemic infarction in the base of the left precentral gyrus as confirmed by brain magnetic resonance imaging. In our patient, cardiogenic embolism or Trousseau syndrome associated with lung cancer was considered the cause of ischemic infarction. Physicians should consider small cortical infarction, when a patient complains of sudden onset of shoulder weakness without pain. In line with the previous reports, a responsible cortical lesion in our patient corresponded to motor shoulder area in the motor homunculus reported to be located more medially to the hand area. PMID:24008130

Kawasaki, Akiko; Suzuki, Keisuke; Takekawa, Hidehiro; Kokubun, Norito; Yamamoto, Masanari; Asakawa, Yohei; Okamura, Madoka; Hirata, Koichi

2013-11-01

116

Sudden death due to undiagnosed acute promyelocytic leukemia: a case report.  

PubMed

Acute promyelocytic leukemia (APL) is associated with severe hemorrhagic coagulopathy induced by the release of procoagulant, plasminogen, and protease from leukemic cells. The case described in this report is of a 15-year-old male who unexpectedly died due to a cerebral hemorrhage caused by underlying APL within 12 h after presentation. This case suggests that underlying APL should be considered as a differential diagnosis when sudden death occurs with a fatal spontaneous hemorrhage, although it is rare. PMID:16741743

Sakai, Kentaro; Takatsu, Akihiro; Shigeta, Akio; Abe, Shuntaro; Ikegami, Masahiro; Takagi, Keizo

2007-07-01

117

Aortoesophageal fistulae due to gunshot wounds: report of two cases with one survivor.  

PubMed

We report the cases of two patients who developed aortoesophageal fistulae after sustaining gunshot wounds to the chest. One suddenly exsanguinated 5 hours postinjury while in the angiography suite. The other manifested 4 weeks postinjury while in a rehabilitation hospital for associated spinal cord injury. The diagnosis and management were complicated, but the patient lived. He is the only survivor of aortoesophageal fistula due to gunshot wound that we could find in the literature. PMID:7602650

Kennedy, F R; Cornwell, E E; Camel, J; Demetriades, D; Fleming, A W

1995-06-01

118

A hepatoid adenocarcinoma of the stomach evaluated with (18)F-FDG PET/CT: intense (18)F-FDG uptake contrary to the previous report.  

PubMed

The condition of a 55-year-old man was diagnosed with unresectable advanced gastric cancer, and initial biopsy revealed adenocarcinoma. On evaluation of treatment response after chemotherapy, F-FDG PET/CT showed large residual stomach cancer with increased FDG uptake (SUVmax, 13.6), lymph node metastasis with mild FDG uptake (SUVmax, 2.5), and no distant metastasis. Palliative subtotal gastrectomy was done, and the finding was hepatoid adenocarcinoma. Compared with the previous report of Pan et al (Clin Nucl Med. 2011;36:1137-1139), our patient had more increased FDG uptake of SUVmax (13.6 vs 1.9) in the gastric mass and lymph node metastases but no liver metastasis. PMID:24152637

Seo, Hyo Jung; Chung, June-Key; Go, Heounjeong; Cheon, Gi Jeong; Lee, Dong Soo

2014-05-01

119

First report of OPA1 screening in Greek patients with autosomal dominant optic atrophy and identification of a previously undescribed OPA1 mutation  

PubMed Central

Purpose To describe the genotype–phenotype correlation in four Greek pedigrees with autosomal dominant optic atrophy (ADOA) and OPA1 mutations. Methods Seven patients from four unrelated families (F1, F2, F3, F4) were clinically assessed for visual acuity, color vision, ptosis, afferent pupillary defects, and visual fields and underwent orthoptic assessment, slit-lamp biomicroscopy, and fundus examination to establish their clinical status. Genomic DNA was extracted from peripheral blood samples from all participants. The coding region (exons 1–28), including the intron-exon boundaries of the OPA1 gene, was screened in the probands of the four families, as well as in seven additional family members (four affected and three unaffected) with PCR and direct DNA sequencing. Results All patients presented bilateral decrease in best-corrected visual acuity and temporal pallor of the optic disc. The visual fields of the adult patients showed characteristic scotomata. Other signs were present in some patients such as decreased color discrimination and a gray crescent within the neuroretinal rim. After the OPA1 gene was sequenced, a previously undescribed heterozygous splice-site mutation c.784–1G>T in intron 7 was detected in family F2. In families F1, F3, and F4, a previously reported in-frame deletion c.876_878delTGT/p.(Val294del), the frameshift c.2366delA/p.(Asn789Metfs*11), and splice-site c.1140+5G>C mutations were detected, respectively. Conclusions This is the first report of molecular characterization of Greek patients with ADOA. Our findings provide additional information regarding the genotype-phenotype correlation and establish the role of the OPA1 gene in Greek patients with ADOA. PMID:24883014

Koutsodontis, George; Tsilimbaris, Miltiadis; Fitsios, Athanasios; Chrousos, Georgia

2014-01-01

120

Hypocalcemia and hypokalemia due to hyperventilation syndrome in spinal anesthesia -A case report-  

PubMed Central

Hyperventilation syndrome (HVS) often occurs under stressful conditions, and has been reported during or after anesthesia and operation. HVS, characterized by multiple somatic symptoms and electrolyte imbalances induced by inappropriate hyperventilation, should be managed as an emergency. We report a rare case of HVS during spinal anesthesia. The patient was a previously healthy 51-year-old female without psychogenic conditions. During spinal anesthesia for lower extremity surgery, the patient complained of nausea, headache, paresthesia in the upper extremities and perioral numbness. We found carpal spasm in both hands and flattening of T wave on electrocardiogram (ECG). Emergent arterial blood gas analysis (ABGA) revealed markedly decreased PaCO2, hypocalcemia and hypokalemia. We managed the patient with verbal sedation, electrolytes replacement therapy and closed mask inhalation. HVS subsided gradually. We conclude that monitoring for possible HVS during anesthesia is very important for patient safety. PMID:22220232

Lee, Soo Kyung; Chung, Ji Hoon; In, Chi Bum

2011-01-01

121

Intussusception due to inflammatory fibroid polyp: A case report and comprehensive literature review  

PubMed Central

AIM: To give an overview of the literature on intussusception due to inflammatory fibroid polyp (IFP). METHODS: We present a new case of ileal intussusception due to IFP and a literature review of studies published in English language on intussusception due to IFP, accessed via PubMed and Google Scholar databases. For the search, the keywords used were: intussusception, IFP, intussusception and IFP, intussusception due to IFP, and IFP presenting as intussusception. The search covered all articles from 1976 to November 2011. RESULTS: We present a 38-year-old woman who was admitted 10 d after experiencing abdominal pain, vomiting, and nausea. Ultrasonography demonstrated small bowel intussusception. An ileal intussusception due to a mass lesion 50 cm proximal to the ileocecal junction was found during laparotomy. Partial ileal resection and anastomosis were performed. A diagnosis of ileal IFP was made based on the immunohistochemical findings. In addition, a total of 56 reports concerning 85 cases of intussusception due to IFP meeting the aforementioned criteria was included in the literature review. The patients were aged 4 to 81 years (mean, 49?±?16.2 years); 44 were women (mean, 51.8?±?14.3 years) and 41 were men (mean, 46?±?17.5 years). According to the location of the IFP, ileal intussusception was found in 63 patients, while 17 had jejunal, three had colonic, and two had ileojejunal intussusception. CONCLUSION: Although IFPs are rare and benign, surgery is the only solution in case of intestinal obstruction. Differential diagnosis should be made via immunohistochemical examination. PMID:23155316

Akbulut, Sami

2012-01-01

122

Ileocolic intussusception due to a cecal endometriosis: Case report and review of literature  

PubMed Central

Abstract Cecal endometriosis and ileocolic intussusception due to a cecal endometriosis is extremely rare. We report a case of a woman who presented an ileocecal intussusception due to a cecal endometriosis. The patient gave two months history of chronic periombilical pain requiring regular hospital admission and analgesia. The symptoms were not related to menses. A laparotomy was performed and revealed an ileocolic intussusception. The abdominal exploration did not find any endometriosis lesion. Ileocaecal resection was performed. Microscopic examination showed a cystic component, lined by a regular cylindric epithelium. Foci of endometrial tissu were oberved in the cecal subserosa and muscularis mucosal, with irregular endometrial glands lined by cylindric epithelium without atypia immunostained with CK7, and characteristic endometrial stroma immunostained with CD10. Cecal endometriosis and ileocolic intussusception due to a cecal endometriosis is extremely rare. Diagnose of etiology remains challenging due to the absence of clinical and radiological specific characteristics. Virtual slide The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2975867306869166 PMID:22676322

2012-01-01

123

Anesthetic management of a repeat cesarean section in a parturient with severe peripartum cardiomyopathy requiring ECMO in a previous pregnancy: a case report.  

PubMed

The number of pregnant women with cardiac disease is increasing with improvements in technology. In addition, more people are part of the national health insurance plan. However, there are few reports concerning the best method for anesthesia and mode of delivery in these high-risk patients. We report a 29-year-old woman scheduled for a planned caesarean section, who had a history of severe peripartum cardiomyopathy requiring extracorporeal membrane oxygenation in a previous pregnancy. The patient had regular prenatal care in our obstetric clinic. At 29 weeks' gestation, she developed severe dyspnea. A chest radiograph revealed bilateral pulmonary edema and 2-dimensional echocardiography showed a global hypokinesis and severe valve regurgitation with left ventricular ejection fraction of 41.2%. She had an emergency caesarean section and a cardiovascular surgeon was consulted to stand-by. Anesthesia was induced by ketamine 25 mg, midazolam 2.5 mg and rocuronium 50 mg for rapid intubation. The patient tolerated the procedure well and was extubated on postoperative day 1. She was discharged one week after surgery. Postoperatively, the patient was followed in the obstetric and cardiovascular surgery outpatient departments and at 5 months after surgery she was in good condition without any complaints. PMID:22490455

Chen, Hsiu-Pin; Sung, Wei-Che; Hui, Yu-Ling; Hui, Chung-Kun

2011-01-01

124

Pott's puffy tumor due to Haemophilus influenzae: case report and review.  

PubMed

Osteomyelitis of the frontal bone may be associated with a purulent collection under the periosteum, causing swelling and edema over the forehead, a condition known as Pott's puffy tumor. We describe an 83-year-old man with a Pott's puffy tumor due to Haemophilus influenzae that was successfully treated with surgery and antibiotics. A review of 22 cases of Pott's puffy tumor shows that this condition usually occurs in children, is spread from frontal or ethmoid sinusitis, and is usually due to streptococci, staphylococci, or anaerobes. Suppurative complications such as epidural, subdural, and intracerebral abscesses are common. Only seven cases of Pott's puffy tumor in adults have been reported, and only one of these cases was caused by H. influenzae. Surgical drainage and antibiotic therapy remain standard therapy for this condition. PMID:8953076

Verbon, A; Husni, R N; Gordon, S M; Lavertu, P; Keys, T F

1996-12-01

125

Clinicoradiological Correlation of Macropsia due to Acute Stroke: A Case Report and Review of the Literature  

PubMed Central

Dysmetropsia (macropsia, micropsia, teleopsia, or pelopsia) most commonly results from retinal pathologies, epileptic seizure, neoplastic lesions, viral infection, or psychoactive drugs. Vascular lesions are an uncommon cause of dysmetropsia. Vascular hemimicropsia, although rare, has been more frequently described in the literature, whereas hemimacropsia from acute ischemic injury is exceedingly rare. We describe a patient presenting in the emergency room (ER) with visual perception disturbances characterized by a distorted perception of the size of objects, compatible with left hemimacropsia. Magnetic resonance imaging (MRI) of the brain showed an acute occipitotemporal ischemic injury corresponding to the posterior cerebral artery (PCA) territory. The location of the lesion is consistent with previous case reports that suggest that hemimacropsia is associated with the occipitotemporal projection, which plays a decisive role in the visual identification of objects by interconnecting the striate, prestriate, and inferior temporal areas. The difference of our case as compared to previous case reports is that the lesion in our patient spared Brodmann area 17 (calcarine cortex) and therefore did not present symptoms of quadrantanopsia. Instead, the patient presented isolated hemimacropsia, therefore suggesting that the anatomical lesion causing hemimacropsia is located in the ventral portion of the occipitotemporal projection, more specifically Brodmann areas 18 (parastriate) and 19 (peristriate).

Montalvo, Mayra Johana; Khan, Muhib Alam

2014-01-01

126

Evidence Report: Risk of Crew Adverse Health Event Due to Altered Immune Response  

NASA Technical Reports Server (NTRS)

The Risk of Crew Adverse Health Event Due to Altered Immune Response is identified by the National Aeronautics and Space Administration (NASA) Human Research Program (HRP) as a recognized risk to human health and performance in space. The HRP Program Requirements Document (PRD) defines these risks. This Evidence Report provides a summary of the evidence that has been used to identify and characterize this risk. It is known that human immune function is altered in- and post-flight, but it is unclear at present if such alterations lead to increased susceptibility to disease. Reactivation of latent viruses has been documented in crewmembers, although this reactivation has not been directly correlated with immune changes or with observed diseases. As described in this report, further research is required to better characterize the relationships between altered immune response and susceptibility to disease during and after spaceflight. This is particularly important for future deep-space exploration missions.

Crucian, Brian; Sams, Clarence F.

2013-01-01

127

[Stenting for cerebral infarction due to stenosis of a persistent primitive proatlantal artery: a case report].  

PubMed

Cerebrovascular disorders complicated by persistent primitive arteries are commonly reported, but, we herein present a 78-year-old man with cerebral infarction due to stenosis of a persistent primitive artery by itself. Cerebral angiography revealed bilateral vertebral artery aplasia to be complicated by a persistent primitive proatlantal artery which had become an important collateral circulation pathway. While the patient was hospitalized because of mild sensory impairment, he also developed visual field constriction and cerebellar symptoms due to recurrent stroke despite anticoagulation treatment. Based on the results of various examinations, cerebral embolism, probably caused by stenosis at the origin of the persistent proatlantal artery, was diagnosed. Carotid artery stenting for the stenosis was planned. A filter protection device was found to be very useful for stenting with maintenance of blood flow in the persistent primitive proatlantal artery. There have been no reports of stenting in persistent primitive proatlantal arteries, such as that our present case is considers. It provides valuable information on the management of this rare disorder. PMID:23269257

Ohhashi, Genichiro; Inoya, Hiroshi

2013-01-01

128

First reported case of reactive airway dysfunction syndrome in a laborer due to porcelain tile dust.  

PubMed

Reactive airway dysfunction syndrome (RADS) is a type of non-immunologically mediated asthma-like disease. It usually occurs after a massive exposure to an irritating substance in the atmosphere in the form of smoke, fumes, gases, and vapor. Unlike bronchial asthma, there is no latency to the symptoms seen in RADS. A number of agents are known to cause RADS, but tile dust, as an etiological agent, has not been previously reported. We report a 45-year-old male laborer, who presented with an acute onset of cough, chest tightness, breathlessness, and audible wheeze after his first time exposure to porcelain tile dust within 5 hours of exposure. Lab tests, including, chest X-ray, electrocardiogram, air blood gas analysis, and serum IgE, were unremarkable. Spirometry showed a mild obstruction [forced expiratory volume in 1 second (FEV1)=72% of predicted], while the bronchodilator reversibility test was significant(14% increase in FEV1 above the baseline).Bronchial biopsy revealed a chronic inflammatory reaction with lymphocytic and plasma cell infiltration and more importantly a striking absence of eosinophils. To the best of our knowledge, this is the first reported case of RADS as a result of exposure to tile dust (porcelain ceramics). PMID:23825894

Arif, Tasleem; Malik, Javid Ahmad; Shoib, Sheikh

2013-06-01

129

First Reported Case of Reactive Airway Dysfunction Syndrome in a Laborer Due to Porcelain Tile Dust  

PubMed Central

Reactive airway dysfunction syndrome (RADS) is a type of non-immunologically mediated asthma-like disease. It usually occurs after a massive exposure to an irritating substance in the atmosphere in the form of smoke, fumes, gases, and vapor. Unlike bronchial asthma, there is no latency to the symptoms seen in RADS. A number of agents are known to cause RADS, but tile dust, as an etiological agent, has not been previously reported. We report a 45-year-old male laborer, who presented with an acute onset of cough, chest tightness, breathlessness, and audible wheeze after his first time exposure to porcelain tile dust within 5 hours of exposure. Lab tests, including, chest X-ray, electrocardiogram, air blood gas analysis, and serum IgE, were unremarkable. Spirometry showed a mild obstruction [forced expiratory volume in 1 second (FEV1)=72% of predicted], while the bronchodilator reversibility test was significant(14% increase in FEV1 above the baseline).Bronchial biopsy revealed a chronic inflammatory reaction with lymphocytic and plasma cell infiltration and more importantly a striking absence of eosinophils. To the best of our knowledge, this is the first reported case of RADS as a result of exposure to tile dust (porcelain ceramics). PMID:23825894

Arif, Tasleem; Malik, Javid Ahmad; Shoib, Sheikh

2013-01-01

130

Hypercalcaemic crisis due to primary hyperparathyroidism - a systematic literature review and case report.  

PubMed

Hypercalcaemic crisis is an uncommon and potentially life-threatening manifestation of primary hyperparathyroidism, and it is associated with rapid deterioration of the central nervous system, and cardiac, gastrointestinal, and renal function. We present the case of a 76 year-old man in a sudden coma due to hypercalcaemic crisis as a first manifestation of primary hyperparathyroidism. At first, the patient was treated conservatively, his mental status gradually improved in the next three days. On the ninth day after the initiation of therapy, a minimally invasive radio-guided parathyroidectomy was performed. Histologically, the tumour consisted of densely arranged chief cells immunohistochemically positive for PTH antigens, suggesting adenoma. Calcaemia level and PTH were normalised in the immediate postoperative period. A systematic review was performed by consulting PubMed MEDLINE for publications from 1958 to 2011. This review found a total of 499 reported cases of hypercalcaemic crisis due to primary hyperparathyroidism. Manifestations are neurological alterations, and cardiac, renal and gastrointestinal dysfunctions associated with markedly elevated serum calcium and parathyroid hormone levels. The most frequent histology is the parathyroid adenoma. In untreated cases, mortality is 100%. Despite advances in its management, the mortality rate is still 93.5% in patients treated only conservatively. Medical therapy followed by expeditious parathyroidectomy should be considered as the treatment of choice for patients affected by hypercalcaemic crisis due to a primary hyperparathyroidism. PMID:23339009

Gurrado, Angela; Piccinni, Giuseppe; Lissidini, Germana; Di Fronzo, Pasquale; Vittore, Francesco; Testini, Mario

2012-01-01

131

Sudden, unexpected death due to glioblastoma: report of three fatal cases and review of the literature  

PubMed Central

Abstract Sudden death from an undiagnosed primary intracranial neoplasm is an exceptionally rare event, with reported frequencies in the range of 0.02% to 2.1% in medico-legal autopsy series and only 12% of all cases of sudden, unexpected death due to primary intracranial tumors are due to glioblastomas. We present three cases of sudden, unexpected death due to glioblastoma, with different brain localization and expression. A complete methodological forensic approach by means of autopsy, histological and immunohistochemical examinations let us to conclude for an acute central dysregulation caused by glioblastoma and relative complication with rapid increase of intracranial pressure as cause of death. Although modern diagnostic imaging techniques have revolutionized the diagnosis of brain tumors, the autopsy and the careful gross examination and section of the fixed brain (with coronal section) is still the final word in determining exact location, topography, mass effects and histology and secondary damage of brain tumor and contributed the elucidation of the cause of death. Immunohistochemistry and proteomic analysis are mandatory in such cases. Virtual slides The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1218574899466985 PMID:23638625

2013-01-01

132

Rupture of an aortic dissection into the right atrium in a patient with a previous aortic valve replacement: a case report.  

PubMed

We report the case of a 73-year-old man with a history of previous aortic valve replacement in 1990 and rupture of an aortic dissection into the right atrium. The patient was admitted to the emergency room because of chest pain, stopped not long after. The electrocardiogram did not show any signs of ischemia and myocardial enzymes were not increased. Transthoracic echocardiography revealed aortic root dilation (maximum diameter 60 mm) extended to the aortic arch, and the presence of a flow from the ascending aorta to the right atrium (evocative of a fistula between the two chambers). The aortic valvular prosthesis function was good. Transesophageal echocardiography confirmed an aorta-right atrium fistula. Cardiac catheterization did not show any luminal obstructions in the coronary arteries; there was a small shunt from the aorta to the right atrium. The ascending aorta and the aortic root were replaced with a Dacron graft. Right and left sinuses were reimplanted to the graft. The fistula was repaired with 4-0 pledgeted Prolene sutures. The surgeon's diagnosis was "type A aortic dissection in a patient with an ascending aorta aneurysm and an old ascending aorta-right atrium fistula". PMID:16161500

Panzarella, Gaetano; Carlino, Gabriella; Fattouch, Kahlil; Ruvolo, Giovanni; Messina, Luigi; Hoffmann, Enrico; Incalcaterra, Egle; Novo, Salvatore

2005-08-01

133

Invasive otitis externa due to Aspergillus species: case report and review.  

PubMed

Aspergillus flavus, an unusual cause of malignant external otitis, was identified in pure culture of tissue from two patients in which histologic examinations demonstrated branching septate hyphae invading the temporal bone. Both patients presented with protracted external ear pain. Multiple attempts at treatment with topical agents (polymyxin B sulfate-neomycin sulfate-hydrocortisone), oral agents (cephalexin and ciprofloxacin), and parenteral agents (ceftazidime and tobramycin) were unsuccessful before definitive diagnosis was made. Treatment with amphotericin B, followed by a more protracted course of itraconazole, resulted in an apparent cure for these patients. Follow-up examination at 15 months after the discontinuation of therapy with itraconazole demonstrated no recurrence of infection. Previously reported cases have predominantly involved immunocompromised persons, and these cases are summarized. PMID:7893871

Gordon, G; Giddings, N A

1994-11-01

134

Axillary artery injury combined with delayed brachial plexus palsy due to compressive hematoma in a young patient: a case report  

PubMed Central

Introduction Axillary artery injury in the shoulder region following blunt trauma without association with either shoulder dislocation or fracture of the humeral neck has been previously reported. Axillary artery injury might also be accompanied with brachial plexus injury. However, delayed onset of brachial plexus palsy caused by a compressive hematoma associated with axillary injury after blunt trauma in the shoulder region has been rarely reported. In previous reports, this condition only occurred in old patients with sclerotic vessels. We present a case of a young patient who suffered axillary artery injury associated with brachial plexus palsy that occurred tardily due to compressive hematoma after blunt trauma in the shoulder region without association of either shoulder dislocation or humeral neck fracture. Case presentation A 16-year-old male injured his right shoulder in a motorbike accident. On initial physical evaluation, the pulses on the radial and ulnar arteries in the affected arm were palpable. Paralysis developed later from 2 days after the injury. Functions in the right arm became significantly impaired. Angiography showed complete occlusion of the axillary artery. Magnetic resonance imaging demonstrated a mass measuring 4 × 5 cm that was suspected to be a hematoma compressing the brachial plexus in a space between the subscapular muscle and the pectoralis minor muscle. Surgery was performed on the third day after injury. In intraoperative observations, the axillary artery was occluded with thrombus along 5 cm; a subscapular artery was ruptured; the brachial plexus was compressed by the hematoma. After evacuation of the hematoma, neurolysis of the brachial plexus, and revascularization of the axillary artery, the patient had an excellent functional recovery of the affected upper limb, postoperatively. Conclusion Surgeons should be aware that axillary artery injuries may even occur in young people after severe blunt trauma in the shoulder region and can be associated with secondary brachial plexus injury due to a hematoma. For treatment in cases with progressive nervous deficit after trauma, not only reconstruction of the injured artery but also immediate evacuation of the hematoma, and exploration of the brachial plexus are necessary to avoid irreversible neurological damage. PMID:18373866

2008-01-01

135

Zoonotic atypical pneumonia due to Chlamydophila psittaci: first reported psittacosis case in Taiwan.  

PubMed

Human psittacosis caused by Chlamydophila psittaci is one of the most common zoonotic atypical pneumonias featuring pulmonary as well as extrapulmonary infections. Most of the cases involve avian contact history especially with psittacine birds. Herein we report a 44-year-old male patient displaying atypical pneumonia symptoms of intermittent fever, dry cough, chest pain, dyspnea, headache, hepatitis, and hyponatremia. He had two sick cockatiels, one of which had died a month previously. A microimmunofluorescence test was performed to check the serum antibody levels against Chlamydophila psittaci. The serum IgM titer showed positive titer of 1:256, 1:256, and 1:128 on Days 11, 23, and 43 after disease onset, respectively. His fever subsided soon and clinical symptoms improved after minocycline was administrated on Day 12. The psittacosis case was confirmed by history of psittacine bird contact, clinical symptoms, treatment response, and positive IgM titer. To our knowledge, this is the first report of a psittacosis case in Taiwan. PMID:23927984

Cheng, Yu-Jen; Lin, Kun-Yen; Chen, Chun-Chen; Huang, Yen-Lin; Liu, Chun-Eng; Li, Shu-Ying

2013-07-01

136

Bromovinyldeoxyurdine treatment of outer retinal necrosis due to varicella-zoster virus: a case-report.  

PubMed

In December 1995, a 70-years old male was referred to us because of rapid visual loss in the right eye, one month after a central retinal artery occlusion in the left eye. This renal transplant patient, with limited renal function, was on immunosuppressive therapy. The diagnosis of bilateral progressive outer retinal necrosis (PORN) due to varicella-zoster virus (VZV) was confirmed by polymerase chain reaction (PCR) detection of VZV DNA in the aqueous fluid. As retinitis progressed despite of intravenous acyclovir administration, the antiviral therapy was switched to oral bromovinyldeoxyuridine (BVDU). This case-report demonstrates that oral BVDU can be a good alternative to acyclovir for the treatment of VZV retinal infections. PMID:9339038

Dullaert, H; Maudgal, P C; Leys, A; Dralands, L; Clercq, E

1996-01-01

137

Acute massive pulmonary thromboembolism due to acute intoxication by duloxetine: a case report.  

PubMed

Duloxetine (Cymbalta) is a potent serotonin norepinephrine reuptake inhibitor used for the management of major depression and pain associated with diabetic peripheral neuropathy. Cymbalta delayed-release capsules contain Duloxetine HCl equivalent to 20, 30, 60 mg of Duloxetine. The ingestion of high quantities of Duloxetine may have serious outcomes such as venous thrombosis, causing cardiac respiratory arrest. The Authors outline a case report of an elderly woman, suffering from depression, found dead in her apartment. The cause of death was attributed to acute massive pulmonary thromboembolism due to acute intoxication of Duloxetine bought the day before. The thesis supported by the authors and confirmed by the data from other studies is that a massive intake of Duloxetine drug increases considerably the medication's side effects such as somnolence, dry mouth, fatigue, insomnia, dizziness, constipation, considerable increases in recumbent systolic and diastolic blood pressure, and a small decrease in heart rate. PMID:22351288

Mari, Francesco; Gualco, Barbara; Rensi, Regina; Bertol, Elisabetta

2012-09-01

138

Adrenal suppression due to an interaction between ritonavir and injected triamcinolone: a case report  

PubMed Central

Two HIV-1 infected patients developed signs and symptoms consistent with adrenal suppression after being exposed to intra-articular triamcinolone acetate while also receiving ritonavir as part of their highly active antiretroviral therapy. Laboratory evaluation confirmed secondary adrenal suppression in both cases. Both patients recovered without the need for chronic replacement steroids. Adrenal suppression has been described as an adverse outcome in patients treated with fluticasone and concomitant ritonavir. In the reported cases, the adrenal suppression likely developed as a result of increased systemic concentrations of triamcinolone due to an inhibition of cytochrome p450 3A4 metabolism. Practitioners of HIV medicine should be aware of the potential negative interaction of injected triamcinolone and ritonavir. PMID:19505306

Dort, Kathryn; Padia, Shetal; Wispelwey, Brian; Moore, Christopher C

2009-01-01

139

Williams College Previous Deans  

E-print Network

Williams College Previous Deans John Chandler 1966 - 1967 Dudley Bahlman 1968 - 1972 Irwin Shainman Reichert 1988 - 1991 Suzanne Graver 1991 - 1994 Mike McPherson 1994 - 1996 David L Smith 1996 - 2000 Tom

Aalberts, Daniel P.

140

Prostate adenocarcinoma associated with prostatic infection due to Schistosoma haematobium. Case report and systematic review.  

PubMed

Schistosomiasis affects more than 240 million people worldwide, an infection which may cause urogenital manifestations including, among others, squamous bladder cancer and prostate involvement. We describe the first case of a prostate adenocarcinoma associated with prostatic Schistosoma haematobium infection occurring in Angola. Prostate carcinoma was suspected because of high levels of prostate-specific antigen. This observation prompted us to review the literature on schistosomiaisis with respect to genital pathology and prostate cancer. Described genital manifestations in men include funiculitis, epididymitis, granulomata of the seminal vesicles, testicular masses, and prostate lesions which may cause haematospermia and infertility. In contrast to bladder cancer, only 12 reports including the present case on 17 cases on prostate carcinoma associated with schistosomiasis have been published worldwide. The rarity of reports on prostate carcinoma associated with schistosomiasis is partly due to diagnostic constraints, and its incidence is underestimated. However, in emerging countries, the incidence of prostate cancer appears to increase mainly as a result of urbanization and improved access to health care where schistosomiasis prevalence is decreasing. PMID:25544700

Figueiredo, Jacinta Chaves; Richter, Joachim; Borja, Nilo; Balaca, Antonino; Costa, Sandra; Belo, Silvana; Grácio, Maria Amélia

2015-02-01

141

Rare and severe complications of congenital adrenal hyperplasia due to 21-hydroxylase deficiency: a case report  

PubMed Central

Introduction We report the case of a patient with classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency who presented with unusual anatomical and biochemical features, namely massively enlarged adrenal glands, adrenogenital rest tissue and an unexpected endocrine profile. The contribution of the adrenocortical cells in the adrenals and testicles was determined by a cosyntropin stimulation test before and after adrenalectomy. To the best of our knowledge this is the first report of such a case in the literature. Case presentation A 35-year-old Caucasian man was admitted to the emergency room with an Addisonian crisis. He had been diagnosed with congenital adrenal hyperplasia in the neonatal period. He acknowledged poor adherence to treatment and irregular medical assistance. Physical examination revealed marked cutaneous and gingival hyperpigmentation, hypotension, and hard nodules in the upper pole of both testicles. Blood analysis showed mild anemia and hyponatremia and no evidence of acute infection. Endocrine evaluation showed very low cortisol levels, low dehydroepiandrosterone-sulfate and elevated corticotropin, 11-deoxycortisol and delta-4-androstenedione. The concentration of 17-hydroxyprogesterone was 20,400ng/dL. After the cosyntropin stimulation test the pattern was similar and there was no significant increase in cortisol or 17-hydroxyprogesterone. The abdominal computed tomography scan revealed grossly enlarged and heterogeneous adrenal glands (left, 12cm; and right, six cm). A bilateral adrenalectomy was performed and pathologic examination revealed adrenal myelolipomas with nodular cortical hyperplasia. The sonogram showed bilateral heterogeneous masses on the upper pole of both testes which corresponded to the nodular hyperplasia of adrenal rest tissues. The genetic study revealed compound heterozigoty (mutations R124H and R356W), suggestive of a phenotypically moderate disease. We performed a cosyntropin stimulation test after adrenalectomy. The steroidogenic profile displayed the same unusual features, indicating an important contribution from the adrenogenital cells. Conclusion This case illustrates that congenital adrenal hyperplasia due to 21-hydroxylase deficiency can progress to severe acute and chronic complications. The masses in the patient’s adrenal glands and testicles resulted from chronically elevated adrenocorticotropic hormone and growth of adrenocortical cells. The basal and stimulated steroid profile, before and after adrenalectomy, revealed an unexpected pattern, suggesting significant contribution of the testicular adrenal cells to the steroidogenesis. PMID:23388220

2013-01-01

142

Oedema of the abductor digiti quinti muscle due to subacute denervation: report of two cases.  

PubMed

The clinical presentation of abductor digiti quinti (ADQ) denervation is often non-specific. The diagnosis is generally clinical and may be easily missed. This case report of two patients describes the magnetic resonance imaging (MRI) finding of unilateral oedema and fatty infiltration isolated to the ADQ. A 36-year old woman who presented with laterally located left foot pain was initially diagnosed as having plantar fasciitis. An MRI scan arranged due to the unusual site of the pain showed increased signal intensity within the ADQ muscle on T1 and T2 images indicating fatty infiltration. Short tau inversion recovery (STIR) images showed hyperintensity of the ADQ indicating oedema. The MRI scan of a 45-year old man who presented with a three month history of left heel pain revealed similar findings. These MRI appearances indicate subacute denervation, which, when involving solely the ADQ muscle suggests entrapment of the first branch of the lateral plantar nerve. Consideration of this imaging finding when examining MRI scans of patients with non-specific heel pain has the potential to facilitate diagnosis. PMID:24480510

Chimutengwende-Gordon, Mukai; O'Donnell, Paul; Cullen, Nicholas; Singh, Dishan

2014-03-01

143

Esophageal obstruction due to enteral feed bezoar: A case report and literature review  

PubMed Central

This paper describes a rare complication of enteral feeding, esophageal obstruction due to feeding formula bezoar, and reviews the published cases. An attempt to re-insert the nasogastric tube in a chronically ventilated 80-year-old female fed via a nasogastric tube with Jevity® failed. An esophagogastroduodenoscopy revealed an 18 cm-long concretion of the feeding formula, filling most of the esophageal lumen, which was removed endoscopically. Forty-two cases of feeding formula esophageal bezoars have been reported in the literature. The formation of feeding formula bezoars is triggered by acidic gastroesophageal reflux. The acidic pH in the esophagus causes clotting of the casein in the formula. Predisposing factors for bezoar formation are: mechanical ventilation, supine position, neurological diseases, diabetes mellitus, hypothyroidism, obesity and history of partial gastrectomy. Diagnosis and removal of the bezoar is done endoscopically. Feeding in a semi-recumbent position, administration of prokinetic agents and proton pump inhibitors may prevent this complication. PMID:21160586

Marcus, Esther-Lee; Arnon, Ron; Sheynkman, Arkadiy; Caine, Yehezkel G; Lysy, Joseph

2010-01-01

144

Amyloid Goiter Due to Familial Mediterranean Fever in a Patient with Byler Syndrome: A Case Report  

PubMed Central

Background: Familial Mediterranean Fever (FMF), also inherited with autosomal recessive trait, is characterized by recurrent episodes of fever, arthritis, and serositis. Congenital Byler Syndrome (Progressive Familial Intrahepatic Cholestasis) inherited with autosomal recessive trait and characterized by defective secretion of bile acids. FMF associated Amyloid A deposition occurs in many tissues and organs, but amyloid goiter is a rare entity that leads to enlargement and dysfunction of the thyroid. Case Report: We present a rare case of 24 year old male patient who had liver and kidney transplantation due to Byler Syndrome and secondary amyloidosis related to FMF, diagnosed as rapidly growing large amyloid goiter. Deposits of extracellular amyloid and dense adipose metaplasia diagnostic for amyloid goiter are determined upon histopathological examination of thyroidectomy material. Conclusion: When goiter was detected in cases with history of systemic amyloidosis and rapidly growing goitre, amyloid goiter should be remembered at first. This case is unique since two autosomal genetic disorders are together in the same patient and important as it emphasizes the consequences of consanguineous marriage, early diagnosis and treatment compliance of FMF and the awareness of amyloid goiter in patients followed by primary care physicians and healthcare professionals. PMID:25337425

Ci?erli, Özlem; Ünal, Asl? Do?ruk; Par?ldar, Hülya; Demiralay, Ebru; Tarç?n, Özlem

2014-01-01

145

Omalizumab in pregnant women treated due to severe asthma: two case reports of good outcomes of pregnancies  

PubMed Central

The article presents case reports of 2 women who became pregnant during therapy with omalizumab. Both subjects suffered from very severe asthma and were treated chronically with all available medications including systemic steroids (first – 20 mg prednisolone/day, second – 40 mg prednisolone/day). Both were enrolled into treatment with omalizumab and started regular therapy in 2007. The course of asthma significantly improved in both cases (withdrawal of oral steroids or significant reduction of their dose, better asthma control). The first woman, 32-year-old, became pregnant in 2010 and gave birth in Oct 2010 – it was her 3rd pregnancy, and 3rd labor. The second woman, 31-year-old, also became pregnant in 2010 and gave birth in Jan 2011 – it was her 5th pregnancy and 2nd labor. Both had severe asthma exacerbations during previous pregnancies and labors, and decided to continue therapy with omalizumab. The first woman, besides omalizumab, was treated with high doses of inhaled corticosteroids (ICS) and long-acting ? agonists (LABA) while the second one was treated with high doses of ICS, LABA and 2.5 mg to 5 mg prednisone/day. The pregnancies proceeded without asthma exacerbations. The first woman delivered a healthy girl (Apgar 9, weight 3200 g, length 56 cm) in the 40th week of pregnancy by caesarean section due to the narrow pelvis. The second one delivered a healthy boy (Apgar 9, weight 3800 g, length 56 cm) in week 40 by caesarean section due to the aggravating obstetrical history. In both cases, treatment with omalizumab did not affect pregnancies and newborns. PMID:25097476

Tworek, Damian; Kuna, Piotr

2014-01-01

146

Cri du Chat Syndrome and Congenital Heart Disease: A Review of Previously Reported Cases and Presentation of an Additional 21 Cases From the Pediatric Cardiac Care Consortium  

Microsoft Academic Search

OBJECTIVES.To analyze the cases submitted to the Pediatric Cardiac Care Consortium (PCCC) database from 1982 to 2002 to determine the frequency and distribution of congenital heart disease (CHD) found in this population, to review the literature for previously published accounts of CHD in this population, and to review current genotype-phenotype associations for cri du chat (CDC) syndrome with CHD. METHODS.We

Christine Hills; James H. Moller; Marsha Finkelstein; Jamie Lohr; Lisa Schimmenti

2010-01-01

147

Bilateral central acetabular fracture dislocation in a young patient due to seizure activity: a case report and review of the literature.  

PubMed

Various musculoskeletal injuries are well known complications of epilepsy either because of direct trauma or because of unbalanced forceful muscle contraction. We report a case of non-traumatic bilateral central acetabular fracture dislocation due to seizure activity induced by neurocysticercosis of the brain, which was managed conservatively and obtained reasonable good outcome. This case highlights the importance of proper evaluation in young non-osteoporotic patients who have experienced an epileptic attack without any previous history. It is also imperative to mention that these patients should be thoroughly examined neurologically to find out the exact etiology and should be treated accordingly to prevent future seizure activity. PMID:25471436

Meena, Umesh Kumar; Meena, Devi Sahai; Behera, Prateek; Meel, Om Singh

2014-12-01

148

Application of the electromagnetic borehole flowmeter and evaluation of previous pumping tests at Paducah Gaseous Diffusion Plant. Final report, June 15, 1992--August 31, 1992  

SciTech Connect

Multi-well pumping tests have been concluded at wells MW79, MW108, and PW1 at the Paducah Gaseous Diffusion Plant (PGDP) to determine the hydraulic properties of the Regional Gravel Aquifer (RGA). Soil cores suggest that the RGA consists of a thin sandy facies (2 to 6 feet) at the top of a thicker (> 10 feet) gravelly facies. Previous analyses have not considered any permeability contrast between the two facies. To assess the accuracy of this assumption, TVA personnel conducted borehole flowmeter tests at wells MW108 and PW1. Well MW79 could not be tested. The high K sand unit is probably 10 times more permeable than comparable zone in the gravelly portion of the RGA. Previous analyses of the three multi-well aquifer tests do not use the same conceptual aquifer model. Data analysis for one pumping test assumed that leakance was significant. Data analysis for another pumping test assumed that a geologic boundary was significant. By collectively analyzing all three tests with the borehole flowmeter results, the inconsistency among the three pumping tests can be explained. Disparity exists because each pumping test had a different placement of observation wells relative to the high K zone delineating by flowmeter testing.

Young, S.C.; Julian, S.C.; Neton, M.J.

1993-01-01

149

Subacute bacterial endocarditis due to Actinobacillus actinomycetemcomitans. Report of a case with a review of the literature.  

PubMed Central

A case of subacute bacterial endocarditis due to Actinobacillus actinomycetemcomitans is reported. The patient was successfully treated first by a combination of gentamicin and ampicillin and then, because of severe allergic reactions, ampicillin was replaced by co-trimoxazole; symptoms did not recur and blood cultures remained sterile. A synoptic table is presented of 19 reported cases of infection caused by A. actinomycetemcomitans not connected with actinomycosis, with particular regard to their clinical features, treatment, and outcome. PMID:915011

Vandepitte, J; De Geest, H; Jousten, P

1977-01-01

150

Native Valve Endocarditis due to Ralstonia pickettii: A Case Report and Literature Review  

PubMed Central

Ralstonia pickettii is a rare pathogen and even more rare in healthy individuals. Here we report a case of R. pickettii bacteremia leading to aortic valve abscess and complete heart block. To our knowledge this is the first case report of Ralstonia species causing infective endocarditis with perivalvular abscess. PMID:25648998

Orme, Joseph; Rivera-Bonilla, Tomas; Loli, Akil; Blattman, Negin N.

2015-01-01

151

Description of a novel Janus kinase 3 P132A mutation in acute megakaryoblastic leukemia and demonstration of previously reported Janus kinase 3 mutations in normal subjects.  

PubMed

Gain-of-function (GOF) mutations of Janus kinase 2 (JAK2) are frequently seen in myeloproliferative disorders (MPDs). Meanwhile, JAK3 activating substitutions have been found in a few megakaryocytic cell lines and in primary myeloid leukemia (AMKL). Here, we sought to discover novel leukemogenetic mutations in de novo acute myeloid leukemia of non-Down syndrome (N-DS) by DNA sequencing. A total of 191 normal Caucasian individuals were studied to define single nucleotide polymorphisms (SNPs) within the JH2 and JH6 domains. Although known activating substitutions were observed in rare cases of acute myeloid leukemia (AML) (V722I [2/134] or P132T [1/119]), all samples were wild-type (WT) for the oncogenic A572V (119/119). Interestingly, a novel homozygous mutation (P132A) was discovered in a patient with acute megakaryoblastic leukemia and in vivo studies demonstrated that its ectopic expression was oncogenic in a mouse xenotransplant model. This study defines a novel JAK3 mutation among patients with N-DS AML and demonstrates that normal individuals can also display germline JAK3 substitutions, previously proven to have oncogenic properties, in vitro and in vivo. The discovery of these substitutions in normal donors encourages future studies to define new risk factors among patients with MPDs. PMID:21599579

Riera, Ludovica; Lasorsa, Elena; Bonello, Lisa; Sismondi, Francesca; Tondat, Fabrizio; Di Bello, Cristiana; Di Celle, Paola Francia; Chiarle, Roberto; Godio, Laura; Pich, Achille; Facchetti, Fabio; Ponzoni, Maurilio; Marmont, Filippo; Zanon, Carlo; Bardelli, Alberto; Inghirami, Giorgio

2011-09-01

152

A rare cause of deep peroneal nerve palsy due to compression of synovial cyst – Case report  

PubMed Central

INTRODUCTION Synovial cyst is a rare cause of compression neuropathy and its differential diagnosis can be misleading. PRESENTATION OF CASE This article presents clinical, radiological, and histological findings of deep peroneal nerve palsy due to compression of a synovial cyst in a 30-year-old patient admitted with sudden drop foot. DISCUSSION Focal nerve entrapment in lower extremity due to synovial cystis a rare entity. Differential diagnosis is important. Surgical excision is the main treatment method with high success rate. CONCLUSION Synovial cyst compression which can be treated easily with surgical excision should be considered in rapidly progressed drop foot. PMID:23567545

Erdil, Mehmet; Ozkan, Korhan; Ozkan, Feyza Unlu; Bilsel, Kerem; Turkmen, Ismail; Senol, Serkan; Sarar, Serhan

2013-01-01

153

The usefulness of chelation therapy for the remission of symptoms caused by previous treatment with mercury-containing pharmaceuticals: a case report  

PubMed Central

Introduction A great deal of data regarding the toxicology of mercury has been recently reported. Although the most common human exposures to mercury are currently mercury vapour from amalgam tooth fillings, methylmercury from seafood and ethylmercury as a preservative in vaccines, in the past mercury compounds have been used in the treatment of syphilis. Case presentation Mercury intoxication was found in a 67 year-old Italian man affected by neurological symptoms of apparently unknown origin. The patient developed syphilis forty years ago and then underwent therapy with mercurials to treat his chronic bacterial infection. We treated the patient with disodium edetate chelation therapy. Six months after the beginning of the therapy, the patient's neurological symptoms began to decrease, and were completely cured after two years of therapy. Conclusion This case supports the use of chelation therapy with disodium edetate to remove damages caused by mercury intoxication. PMID:19946446

2009-01-01

154

Benign Leptospirosis: First Reported Outbreak in British Isles due to Strains Belonging to the Hebdomadis Serogroup of Leptospira Interrogans  

Microsoft Academic Search

The clinical and epidemiological features associated with the first reported outbreak in the British Isles of benign anicteric leptospirosis, due to strains belonging to the hebdomadis subgroup, are described. Four cowherdsmen working in two dairy farms in Surrey developed a febrile illness which was not associated with jaundice, but aseptic meningitis was a feature. Microscopic agglutination tests with formolized antigen

Alex Sakula; William Moore

1969-01-01

155

A case of human enteric myiasis due to larvae of Hermetia illucens (Family: Stratiomyiadae): first report in Malaysia.  

PubMed

A case of true enteric myiasis in a 7-year-old girl is reported. Two larvae were obtained from the vomitus of the patient. After processing and identification, the larvae were found to be those of Hermetia illucens (Soldier Fly). This is the first case of true enteric myiasis due to these larvae in Malaysia. PMID:8935136

Lee, H L; Chandrawathani, P; Wong, W Y; Tharam, S; Lim, W Y

1995-12-01

156

Management of chronic lateral instability due to lateral collateral ligament deficiency after total knee arthroplasty: a case report  

Microsoft Academic Search

INTRODUCTION: Lateral instability following total knee arthroplasty (TKA) is a rare condition with limited report of treatment options. The objective of this case presentation is to demonstrate the outcomes of different surgical procedures performed in a single patient with lateral collateral ligament (LCL) deficiency. CASE PRESENTATION: We present a case of chronic lateral instability due to LCL deficiency after primary

Aasis Unnanuntana; James E Murphy; William J Petersilge

2010-01-01

157

Spontaneous ilio-iliac arteriovenous fistula due to an iliac artery aneurysm: a case-report.  

PubMed

A spontaneous arterio-venous ilioiliac fistula (AVF) caused by an iliac artery aneurysm (IAA) is a rare complication. We present the case of a 75-year-old man with previous aortic surgery 11 years before who was admitted at the Emergency Department for acute gluteal pain. He was suspected for a hip problem because of cup loosening on X-ray. A lumbar CT-scan to rule out nerve compression showed an aneurysm of the left common and internal iliac artery that was ruptured into the iliac vein. The AVF was treated endovascularly under local anesthesia by a sandwich technique (covered stent at the venous side and coils at the arterial side) with good results. The case demonstrates that lifelong follow-up of a patient with previous aortic surgery is mandatory. PMID:22571082

Vandereyken, F; Schwagten, V; Hertoghs, M; Beaucourt, L; D'Archambeau, O; Hendriks, J

2012-01-01

158

Unusual cause of right iliac fossa pain: sigmoid perforation due to ingested rabbit bone. Case report.  

PubMed

Disorders of an organ not usually found in the right iliac fossa, such as the sigmoid colon, are an uncommon cause of right iliac fossa pain. We present a case of right iliac fossa pain caused by a sigmoid perforation due to involuntary ingestion of a rabbit bone, and describe the main features of this condition. PMID:22018217

Iusco, D R; Jannaci, M; Grassi, A; Corazza, F; Virzì, S

2011-10-01

159

Disseminated Aspergillosis due to Aspergillus niger in Immunocompetent Patient: A Case Report  

PubMed Central

Invasive aspergillosis is a major cause of morbidity and mortality in immunocompromised patients. Many cases of pulmonary, cutaneous, cerebral, and paranasal sinus aspergillosis in immunocompetent patient were defined in literature but disseminated aspergillosis is very rare. Here we present an immunocompetent case with extrapulmonary disseminated aspergillosis due to Aspergillus niger, totally recovered after effective antifungal treatment with voriconazole. PMID:23533852

Ergene, Ulku; Akcali, Zeynep; Ozbalci, Demircan; Nese, Nalan; Senol, Sebnem

2013-01-01

160

The Cost of Special Education Due Process Fair Hearings and Appeals in California. Final Project Report.  

ERIC Educational Resources Information Center

The California State Board of Education authorized the study to document the overall costs of special education due process fair hearings to all parties--the parents, local education agencies, and the state. The study also analyzed the factors that enter into the costs of hearings, and some conclusions were drawn and recommendations made for…

Peterson, Gerald P.; Ayer, Sue F.

161

A multiplanar complex resection of a low-grade chondrosarcoma of the distal femur guided by K-wires previously inserted under CT-guide: a case report  

PubMed Central

Background In muscular skeletal oncology aiming to achieve wide surgical margin is one of the main factors influencing patient prognosis. In cases where lesions are either meta or epiphyseal, surgery most often compromises joint integrity and stability because muscles, tendons and ligaments are involved in wide resection. When lesions are well circumscribed they can be completely resected by performing multi-planar osteotomies guided by computer-assisted navigation. We describe a case of low-grade chondrosarcoma of the distal femur where a simple but effective technique was useful to perform complex multiplanar osteotomies. No similar techniques are reported in the literature. Case presentation A 57 year-old Caucasian female was referred to our department for the presence of a distal femur chondrosarcoma. A resection with the presenting technique was scheduled. The first step consists of inserting several K-wires under CT-scan control to delimitate the tumor; the second step consists of tumor removal: in operative theatre, following surgical access, k-wires are used as guide positioning; scalpels are externally placed to k-wires to perform a safe osteotomy. Conclusions Computed assisted resections can be considered the most advantageous method to reach the best surgical outcome; unfortunately navigation systems are only available in specialized centres. The present technique allows for a multiplanar complex resection when navigation systems are not available. This technique can be applied in low-grade tumours where a minimal wide margin can be considered sufficient. PMID:25123066

2014-01-01

162

The Assessment of Tumor Response by Measuring the Single Largest Lesion per Organ in Metastatic Tumors: A Pooled Analysis of Previously Reported Data  

PubMed Central

Background: The RECIST 1.1 adopted a total of five target lesions to be measured, with a maximum of two lesions per organ. To the best of our knowledge, the criterion of two target lesions per organ in the RECIST 1.1 is arbitrary and has not been supported by any objective evidence. Recently, we reported that the modified RECIST 1.1 (measuring the single largest lesion in each organ) showed a high level of concordance with the original RECIST 1.1 in patients with advanced or metastatic non-small cell lung cancer (NSCLC), gastric cancer (GC), and colorectal cancer (CRC). However, each study had a major limitation of a small number of patients. Methods: We conducted a pooled analysis using the data from the three individual studies to improve statistical power. Tumor responses were compared according to the RECIST 1.1 and modified RECIST 1.1 (mRECIST 1.1). Results: A total of 153 patients who had at least two target lesions in any organ according to the RECIST 1.1 were included in this pooled study: 64 with NSCLC, 51 with GC, and 38 with CRC. Regardless of primary sites, the number of target lesions according to the mRECIST 1.1 was significantly lower than that according to the RECIST 1.1 (P<0.001). The assessment of tumor responses showed a high concordance between the two criteria (k = 0.908). Only eight patients (5.2%) showed disagreement in the tumor response assessment between the two criteria. The overall response rates of chemotherapy were not significantly different between the two criteria (33.3% versus 33.3%, P=1.0). Conclusions: The modified RECIST 1.1 was comparable to the original RECIST 1.1 in the tumor response assessment of patients with advanced or metastatic NSCLC, GC, and CRC. Our results suggest that it may be possible to measure the single largest lesion per organ for assessing tumor response in clinical practice.

Jang, Hyun Joo; Cho, Ji Woong; Park, Bumjung; Choi, Hyun Chang; Kim, Hyeong Su; Kim, Jung Han

2015-01-01

163

Gastric Dilation due to a Neuroleptic Agent in an Elderly Patient: A Case Report  

PubMed Central

Neuroleptics may cause side effects, some of which are little known. We describe here a case of gastric dilation related to treatment with a neuroleptic in an elderly man. To our knowledge, such a case has never been reported in the literature. A 76-year-old man, living in a nursing home, was hospitalized for general weakness and abdominal pain. He had dementia with behavioral disorders treated with cyamemazine, a sedative and anxiolytic neuroleptic. Given a clinical suspicion of intestinal occlusion, an abdominopelvic computerized tomography scan was performed before the patient was admitted to our hospital. This computerized tomography scan did not show intestinal occlusion and there was no mention of gastric dilation in the computerized tomography scan report. Thus, acute gastroenteritis was suspected. The usual medications were stopped and symptomatic treatment for gastroenteritis was started. Quickly, his clinical state and biological parameters returned to normal and his usual treatment, including cyamemazine, was started again. The next day, the digestive symptoms, except for obstipation, reappeared. The abdominal X-ray showed gastric dilation without intestinal occlusion. The neuroleptic was stopped again and symptoms vanished the next day. This report underlines all of the necessary precautions and surveillance around drug prescription, especially in elderly persons. PMID:25161671

Parent, V.; Popitean, L.; Loctin, A.; Camus, A.; Manckoundia, P.

2014-01-01

164

Jod-Basedow effect due to prolonged use of lugol solution-case report.  

PubMed

Graves' disease is the most common form of hyperthyroidism, accounting for 60-80% of all cases of thyrotoxicosis. If left untreated, it may lead to severe thyrotoxicosis with cardiovascular, ocular, psychiatric complication, and in extreme cases thyrotoxic crisis with a high mortality rate. We present the case of a 50-years-old woman diagnosed in another service with Graves' disease and treated for many years with antithyroid drugs (ATDs), admitted to our service for a relapse due to treatment discontinuation. The surgical treatment was planned and the preoperative preparation with Lugol solution was initiated. Due to a misunderstanding, the administration of iodine solution was extended for a period of about 30 days, thus generating the so-called Jod-Basedow effect, with the exacerbation of the manifestations of thyrotoxicosis and risk of thyroid storm. The patient received treatment with high ATDs doses, glucocorticoids, and beta-blockers, resulting in the progressive improvement of symptoms. She was discharged from hospital and given the risk of thyrotoxic crisis the surgery was postponed. After a month, the patient underwent thyroidectomy without preoperative preparation with iodine solution. The operative and postoperative courses were uneventful. PMID:25581962

Leu?tean, Leti?ia; Preda, Cristina; Ungureanu, Maria-Christina; D?nil?, R; Mogo?, Voichi?a; Stef?nescu, Cipriana; Vulpoi, Carmen

2014-01-01

165

[Gangrene of the penis due to strangulation by a rubber band: a case report].  

PubMed

We report a case of strangulation of the penis by a rubber band. A 79-year-old man placed a rubber band tightly around the corona of his glans penis in order to prevent urinary incontinence. After five days, he was taken to our hospital in an ambulance for high temperature and general malaise. We found the rubber band and removed it immediately. Gangrene of the penis continued and he did not recover from sepsis, so we performed partial penectomy. After the operation, he completely recovered. Penile strangulation using a soft constricting object such as a rubber band might result in severe complications and we should be careful. PMID:24759505

Sasaki, Yutaro; Oda, Shinpei; Fujikata, Shiro; Tanimoto, Shuji; Kan, Masaharu

2014-03-01

166

Phytocontact dermatitis due to Ranunculus arvensis mimicking burn injury: report of three cases and literature review  

PubMed Central

Ranunculus arvensis (corn buttercup) is a plant species of the genus Ranunculus that is frequently used in the Far East to treat rheumatic diseases and several dermatological disorders. In Turkey, the plant is seen in the eastern and southeastern Anatolian highlands, which are underdeveloped areas of the country. Herein, we report three patients who used Ranunculus arvensis for the treatment of arthralgia and osteoarthritis. A distinctive phytodermatitis developed on the right thumb in one patient (48-year-old male), on the anterior aspect of both knees in another patient (70-year-old female) and all around both knees in a third (59-year-old female). The patients were treated with topical antibiotics and daily wound dressing, and none of them experienced any complications. Ranunculus arvensis was confirmed as the cause of the phytodermatitis in the three cases. Poultices of plants applied to the skin demonstrate beneficial effects on many dermatological and rheumatic diseases; however, they have several adverse effects that should not be ignored. In this study, we also present a review of 25 cases reported in the literature. PMID:21408003

2011-01-01

167

Acute kidney injury due to sodium bromate intoxication: a report of two cases.  

PubMed

Sodium bromate is a strong oxidant used as a neutralizing solution in hair permanents, as well as an auxiliary agent in printing and dyeing. Accidental or deliberate ingestion of bromate solution has rarely been reported in Korea. The clinical manifestations of bromate intoxication are vomiting, diarrhea, central nervous system symptoms, oliguric or non-oliguric acute kidney injury, hemolytic anemia, and deafness; most of these manifestations are reversible, with the exception of renal failure and deafness. Here, we report on two patients who demonstrated distinct clinical progressions. In the first case, a 16-year-old woman was successfully treated with hemodialysis and recovered renal function without hearing loss. However, in the second case, delayed hemodialysis resulted in persistent renal failure and hearing loss in a 77-year-old woman. This suggests that emergency therapeutic measures, including hemodialysis, should be taken as soon as possible, as the rapid removal of bromate may be essential to preventing severe intoxication and its sequelae. PMID:22205849

Ryu, Dong Hwan; Jang, Kyung Ae; Kim, Seok Min; Park, Jong Won; Do, Jun Young; Yoon, Kyung Woo

2011-12-01

168

Hypoglycemic coma due to insulin autoimmune syndrome induced by methimazole: A rare case report.  

PubMed

Insulin autoimmune syndrome (IAS) is a rare cause of hypoglycemia characterized by the presence of insulin-binding autoantibodies and fasting or late postprandial hypoglycemia. The number of reports on the association of human leukocyte antigen (HLA) genotype with this disease in adolescents in China is limited. This is the case report of a 17-year-old female patient with Graves' disease who was treated with methimazole (MTZ). After 4 weeks of continuous MTZ treatment, the patient suffered an episode of unconsciousness during the late postprandial phase and was admitted to the hospital, where the blood glucose level was found to be 2.88 mmol/l. The symptoms were relieved following intravenous glucose administration. Imaging studies of the pancreas were unremarkable, but the laboratory investigations on admission revealed high serum levels of total insulin, associated with relatively low levels of free insulin and markedly elevated insulin autoantibody (IAB) levels. HLA testing revealed DRB1(*)0406/0901 and the patient discontinued MTZ and was prescribed propylthiouracil. During the long-term follow-up, the total insulin and IAB levels gradually declined. There was no other episode of hypoglycemia. Therefore, in adolescents with Graves' disease receiving antithyroid treatment with MTZ who experience hypoglycemia, the IAB levels should be assessed to exclude or confirm IAS as the underlying cause. PMID:25289063

Zhang, Yiyi; Zhao, Tieyun

2014-11-01

169

Enterocolic fistula due to a rectal stent: Case report and literature review  

PubMed Central

Introduction Self-expanding metal stents (SEMS) are successfully being used to acutely relieve obstructing colorectal cancers; yet, their use does not come without complications. Presentation of case We present a case in which a patient with a recurrent obstructing sigmoid carcinoma underwent colonic stenting for acute decompression. Two months after stent placement, an enterocolic fistula formed from erosion of the upper end of the stent. Discussion An extensive literature review revealed that fistula formation, as a complication of stent placement, is rarely reported. Presentation of the case is followed by a review of complications that may arise following SEMS placement, with a focus on enterocolic fistulae. To our knowledge, this work provides the most extensive review of the subject to date. Conclusion SEMS provide an effective, safe, and less invasive option for patients when used in the appropriate clinical context. Further reports of enterocolic fistulae as a complication of SEMS placement are necessary in order to better understand this potential adverse event. PMID:25568798

Ross, John P.; Orkin, Bruce A.

2014-01-01

170

Bilateral testicular self-castration due to cannabis abuse: a case report  

PubMed Central

Introduction The self-mutilating patient is an unusual psychiatric presentation in the emergency room. Nonetheless, serious underlying psychiatric pathology and drug abuse are important background risk factors. A careful stepwise approach in the emergency room is essential, although the prognosis, follow-up, and eventual rehabilitation can be problematic. We present a unique and original case of bilateral self-castration caused by cannabis abuse. Case Presentation We report a case of a 40-year-old Berber man, who was presented to our emergency room with externalization of both testes using his long fingernails, associated with hemodynamic shock. After stabilization of his state, our patient was admitted to the operating room where hemostasis was achieved. Conclusion The clinical characteristics of self-mutilation are manifold and there is a lack of agreement about its etiology. The complex behavior associated with drug abuse may be one cause of self-mutilation. Dysfunction of the inhibitory brain circuitry caused by substance abuse could explain why this cannabis-addicted patient lost control and self-mutilated. To the best of our knowledge, this is the first case report which presents an association between self-castration and cannabis abuse. PMID:21861879

2011-01-01

171

Acute Kidney Injury due to Sodium Bromate Intoxication: A Report of Two Cases  

PubMed Central

Sodium bromate is a strong oxidant used as a neutralizing solution in hair permanents, as well as an auxiliary agent in printing and dyeing. Accidental or deliberate ingestion of bromate solution has rarely been reported in Korea. The clinical manifestations of bromate intoxication are vomiting, diarrhea, central nervous system symptoms, oliguric or non-oliguric acute kidney injury, hemolytic anemia, and deafness; most of these manifestations are reversible, with the exception of renal failure and deafness. Here, we report on two patients who demonstrated distinct clinical progressions. In the first case, a 16-year-old woman was successfully treated with hemodialysis and recovered renal function without hearing loss. However, in the second case, delayed hemodialysis resulted in persistent renal failure and hearing loss in a 77-year-old woman. This suggests that emergency therapeutic measures, including hemodialysis, should be taken as soon as possible, as the rapid removal of bromate may be essential to preventing severe intoxication and its sequelae. PMID:22205849

Ryu, Dong Hwan; Jang, Kyung Ae; Kim, Seok Min; Park, Jong Won; Yoon, Kyung Woo

2011-01-01

172

Evaluation of the electromagnetic effects due to direct lighting to nuclear explosive areas at Pantex. Final report  

SciTech Connect

This report summarizes the effort to quantify the electromagnetic environments in the nuclear explosive areas at Pantex due to direct lightning. The fundamental measure of the threat to nuclear safety is assumed to be the maximum voltage between any two points in an assembly area, which is then available for producing arcing or for driving current into critical subsystems of a nuclear weapon. This maximum voltage has been computed with simple analytical models and with three-dimensional finite-difference computer codes.

Merewether, K.O.; Chen, K.C.

1993-11-01

173

[Case report: Aneurysmatic subarachnoid hemorrhage - Complicated course due to coincidental manifestation of an inverted Tako-Tsubo-cardiomyopathy].  

PubMed

We report the case of a patient who suffered a serious subarachnoid hemorrhage with a cardialaffection and development of an inverted Tako-Tsubo-cardiomyopathy. To avoid apparent cerebral ischemia due to severe cerebral vasospasm after exhaustion of conservative therapeutic options a temporarily endovascular therapy with continuous intra-arterial application of Nimodipine was necessary. In the overall protracted and complicated course the special challenge were the therapeutic efforts to avoid apparent cerebral ischemia in context to the significant cardial affection. PMID:25137200

Zech, Nina; Kieninger, Martin; Seemann, Milena; Künzig, Holger; Bele, Sylvia; Dietl, Alexander

2014-07-01

174

Microvascular decompression for hemifacial spasm due to four offending vessels: a case report.  

PubMed

A 65-year-old woman presented with left facial involuntary movement and facial palsy for eight years. Brain magnetic resonance image (MRI) and magnetic resonance angiography (MRA) revealed multiple vascular compression of facial nerve root exit zone (REZ). Standard retromastoid suboccipital craniectomy and arachnoid dissection were performed. Right vertebral artery (VA), left VA, left anterior inferior cerebellar artery (AICA), and left posterior inferior cerebellar artery (PICA) compressed the facial nerve in that order. The offending vessels were dissected away from the facial nerve and transposed sequentially. Teflon was interposed between the arteries and the nerve. Electrophysiological monitoring showed disappearance of the abnormal hemifacial spasm response during the operation. The offending vessels were right VA, left VA, left AICA, and left PICA. Postoperatively, the patient's involuntary movement was completely resolved. We report a rare case of hemifacial spasm caused by four offending vessels that was treated by microvascular decompression (MVD) with wide arachnoid dissection. PMID:23546911

Choi, Hyuk Jai; Choi, Seok Keun; Rhee, Bong Arm

2013-01-01

175

Iron deficiency anemia due to lymphocytic gastritis with Helicobacter pylori infection in childhood: case report.  

PubMed

Lymphocytic gastritis (LG) is a chronic inflammatory process of poorly understood pathogenesis. We report the case of a 12-year-old premenstrual girl with refractory iron deficiency anemia in which the oral iron absorption challenge suggested iron malabsorption. Laboratory studies ruled out celiac disease and autoimmune gastritis, and carbon-13 urea breath test for Helicobacter pylori was also negative. Upper endoscopy with gastric body and antral mucosa biopsies revealed a LG with focal intestinal metaplasia and H. pylori infection. H. pylori eradication was undertaken with success and 3 months later her hematologic parameters normalized. Histologic reevaluation showed disappearance of LG. This case shows that investigation of malabsorption disease in the presence of refractory iron deficiency anemia can lead to the diagnosis of important gastric diseases, even in the absence of gastrointestinal symptoms. This nonceliac child was diagnosed with a severe histopathologic pattern of LG, with potential risk of malignant transformation, which was completely reverted with adequate H. pylori eradication treatment. PMID:23528908

Santalha, Marta F F; Costa, Emília; Miguel, Natalina; Vizcaíno, Ramón; Barbot, José; Pereira, Fernando

2013-05-01

176

Drug-induced liver injury due to "natural products" used for weight loss: a case report.  

PubMed

Taking herbal-extracts to lose weight is an underestimated health hazard. Often, these products contain active agents that can cause acute liver damage. In this case report, a 22-year-old female patient, who presented with a feature of cholestatic syndrome, was so sure that the "natural products" were not dangerous that she did not inform her physicians that she had taken them, making their task that much more challenging. Clinical presentation mimicked acute cholecystitis and the patient underwent a cholecystectomy. Surgery was without any consequences and complications, although it did not completely cure the illness. She later admitted to having taken herbal remedies and this led to the correct diagnosis of phytotherapy-related hepatotoxicity and a successful therapeutic approach. The true incidence of phytotherapy-related hepatotoxicity and its pathogenic mechanisms are largely unknown. It is important to increase the awareness of both clinicians and patients about the potential dangers of herbal remedies. PMID:19452589

Tarantino, Giovanni; Pezzullo, Martina Gilda; di Minno, Matteo Nicola Dario; Milone, Francesco; Pezzullo, Luigi Sossio; Milone, Marco; Capone, Domenico

2009-05-21

177

Drug-induced liver injury due to “natural products” used for weight loss: A case report  

PubMed Central

Taking herbal-extracts to lose weight is an underestimated health hazard. Often, these products contain active agents that can cause acute liver damage. In this case report, a 22-year-old female patient, who presented with a feature of cholestatic syndrome, was so sure that the “natural products” were not dangerous that she did not inform her physicians that she had taken them, making their task that much more challenging. Clinical presentation mimicked acute cholecystitis and the patient underwent a cholecystectomy. Surgery was without any consequences and complications, although it did not completely cure the illness. She later admitted to having taken herbal remedies and this led to the correct diagnosis of phytotherapy-related hepatotoxicity and a successful therapeutic approach. The true incidence of phytotherapy-related hepatotoxicity and its pathogenic mechanisms are largely unknown. It is important to increase the awareness of both clinicians and patients about the potential dangers of herbal remedies. PMID:19452589

Tarantino, Giovanni; Pezzullo, Martina Gilda; Dario di Minno, Matteo Nicola; Milone, Francesco; Pezzullo, Luigi Sossio; Milone, Marco; Capone, Domenico

2009-01-01

178

Rectal obstruction due to endometriosis: A case report and review of the Japanese literature  

PubMed Central

INTRODUCTION Colorectal obstructive endometriosis is relatively rare in Japan and its differentiation from malignancy is often difficult. We report a case of rectal obstructive endometriosis. PRESENTATION OF CASE A 37-year-old woman was referred to our hospital with a suspected ileus. Her chief symptoms were left lower abdominal pain and vomiting. Colonoscopy showed an intraluminal mass of redness in the upper rectum. A proctectomy was performed because of the bowel obstruction. The rectum was filled with an intraluminal mass measuring 5 cm × 4 cm, and endometriosis was diagnosed pathologically. DISCUSSION A preoperative diagnosis of colorectal obstructive endometriosis is often difficult because of the lack of definite diagnostic, clinical, sonographic, or radiological findings that are characteristic of this disease. Medical treatment is not always effective for colorectal obstructive endometriosis, and surgery is often performed. CONCLUSION Colorectal obstructive endometriosis should be considered as a differential diagnosis in cases of various gastrointestinal symptoms in women who are of reproductive age. PMID:25462048

Ono, Hiromi; Honda, Shohei; Danjo, Yasushi; Nakamura, Kenji; Okabe, Mihiro; Kimura, Takashi; Kawakami, Masato; Nagashima, Kimimoto; Nishihara, Hiroshi

2014-01-01

179

Bacteremia due to Campylobacter in renal transplantation: a case report and review of literature.  

PubMed

Campylobacter species are the leading cause of acute bacterial diarrhea in industrialized countries. However, bacteremia is detected in <1% of patients with Campylobacter enteritis and is most likely to occur in patients who are immunocompromised or of older age. To our knowledge, only 2 cases of Campylobacter jejuni bacteremia have been reported in renal transplant recipients (RTRs). We present a case of an RTR with C. jejuni bacteremia presenting as self-limiting diarrhea followed by fever and cellulitis. The patient was successfully treated with a 2-week course of imipenem and developed no other complications. We review all cases of Campylobacter bacteremia in RTRs, and discuss clinical presentation and treatment of this potentially fatal disease. PMID:25296529

Pereira, L; Sampaio, S; Tavares, I; Bustorff, M; Pestana, M

2014-12-01

180

[Catamenial pneumothorax due to diaphragmatic endometriosis confirmed by histological examination; report of a case].  

PubMed

We reported a case of catamenial pneumothorax caused by diaphragmatic endometriosis that was histologically confirmed. A 49-year-old female who had recurrent chest pain and cough appearing on the day preceding each menstruation from 5 years ago. These episode suggested catamenial pneumothorax. Thoracotomy revealed the characteristic appearances of catamenial pneumothorax such as blueberry spots and multiple small holes on the central tendon of the right diaphragm. But there were no lesions on the visceral pleura of the lung. Partial resection of the diaphragm including these lesions were performed. Histological examination showing positive for estrogen receptor and progesterone receptor confirmed the presence of endometrial tissue on the diaphragm. The patient has been well controlled by therapy with gonadotropin releasing hormone, without recurrence of catamenial pneumothorax. PMID:21591450

Segawa, M; Touge, M; Kusajima, Y; Saito, K

2011-05-01

181

Remote cerebellar hemorrhage due to ventriculoperitoneal shunt in an infant: a case report  

PubMed Central

Introduction Cerebellar hemorrhage remote from the operative site is an unpredictable and rare complication in neurosurgery, with reported rates of morbidity and mortality in the literature of 8.4% and 7.8%, respectively. The range of procedures associated with remote cerebellar hemorrhage is diverse and includes both supratentorial and spinal procedures that entail significant cerebral spinal fluid loss or resection of supratentorial content. We present here the first documented case of remote cerebellar hemorrhage after controlled supratentorial cerebral spinal fluid drainage by ventriculoperitoneal shunt, and discuss the proposed pathophysiology and treatment. Case presentation We present the case of a four-month-old Saudi Arabian male baby who presented with progressive symptoms and signs of congenital hydrocephalus. An uneventful ventriculoperitoneal shunting was performed with our patient recovering smoothly in the immediate postoperative period. On the next day, he had frequent episodes of vomiting and became lethargic. An urgent computed tomography scan of his brain revealed mild ventricular decompression and unexpected cerebellar hemorrhage. The infant was put under close observation, with marked spontaneous improvement over 48?hours and complete resolution of the hemorrhage on a follow-up computed tomography brain scan two weeks later. On regular outpatient visits at one, three and twelve months, he had no neurological deficit. Conclusion Remote cerebellar hemorrhage is a complication that remains enigmatic in terms of both the underlying mechanism and clinical behavior. Our case revealed that the risk factors identified in the literature are not sufficient in predicting patients at risk of developing remote cerebellar hemorrhage. Our report also adds to the growing body of evidence challenging the currently accepted hypothesis explaining the pathomechanism of remote cerebellar hemorrhage. It thereby remains an unpredictable hazard that requires further study and increased awareness, as many cases in the literature are incidental findings. PMID:22846583

2012-01-01

182

[Anaphylaxis Due to Ingestion of Ivy Syrup (Hedera hÈlix). Report of two Cases].  

PubMed

Common ivy is an ornamental plant, that is ubiquitous in Mexico. Its allergens can cause contact dermatitis, asthma and allergic rhinitis. We describe two cases of anaphylaxis related to common ivy syrup ingestion. We performed skin prick test with Hedera helix syrup, and using a dialized and ultrafiltered of common ivy syrup commercial presentation (dry common ivy extract: 7mg/ml), as well as using Hedera helix pollen extract. We describe two cases of anaphylaxis related to ingestion of Hedera helix syrup. Skin prick test with the commercial presentation and with the pollen extract were positive in both patients. In this study we confirmed the causal relationship of anaphylaxis due to the ingestion of ivy syrup in two patients through skin prick tests with ivy syrup and ivy pollen extract. Common ivy can cause contact dermatitis, asthma and allergic rhinitis, but we do not know the allergens that could be related to systemic and respiratory reactions, then, more studies in this topic are requiered. PMID:24007931

Morfin-Maciel, Blanca María; Rosas-Alvarado, Alejandro; Velázquez-Sámano, Guillermo

2012-01-01

183

[Lumbo-pelvic stabilisation following subtotal sacrectomy due to a giant invasive schwannoma. Case report].  

PubMed

The case of a rare giant invasive schwannoma of the sacrum is presented. This is a slow-growing tumour reaching a large size because of non-specific symptoms. Even though it is benign in nature, it has characteristics markedly differing from commonly-known neurinomas; it invades and destroys bone, on MR examination it shows a heterogeneous structure reminiscent of a malignant process and its growth around the nerve roots makes nerve dissection in the cauda equina very complicated. At the time of diagnosis a major part of the sacral bone is usually destroyed and nerve root dissection is very difficult. In this case, because of removal of most of the tissue, an almost complete sacrectomy was necessary including the sacral roots with the exception of S1. At the second stage, lumbo-pelvic stabilisation was carried out using the modified Galveston technique. Since only a very few similar cases have been reported, it is not possible to predict the post-operative outcome in terms of potential recurrence or residual progression. In our patient a small residuum was stable even at 37 months after surgery. She remained incontinent after surgery, but able to walk unaided. Radiographic examination showed the osteosynthetic material without signs of loosening and in a good position. PMID:22094162

Haninec, P; Kaiser, R; Skála-Rosenbaum, J

2011-01-01

184

Sudden death due to diabetic coma in insulin-department diabetes mellitus: an autopsy report.  

PubMed

Sudden death caused by the acute onset of diabetic coma is reported. A 15-year-old female had been suffering from insulin-dependent diabetes mellitus for the prior 8 years and had a fever and vomiting for the past few days. On the 4th day, after the onset of fever and vomiting, she died suddenly, and was autopsied to clarify the cause of death. Macroscopic examination revealed that the pancreas was atrophic (40 g) whereas the liver was markedly enlarged (2,740 g). Histological findings were: 1) The islets of Langerhans were decreased in size and number. They were not positive for aldehyde-fuchsin staining, 2) There were severe fatty changes in the liver cells. The retained blood in the left ventricle was analyzed: glucose, 1,016 mg/dl; acetone, 345 mg/l; acetoacetate, 5.91 mmol/l: D-3-hydroxybutyrate, 4.17 mmol/l; hemoglobin A1c, 10.2%; fructosamine, 416 mumol/l; total serum cholesterol, 220 mg/dl; triglycerides, 205 mg/dl; free fatty acid, 8.0 mEq/l; urea nitrogen, 40 mg/dl. Although the biochemical estimation of the glucose and ketone levels in post-mortem body fluids was recognized as being unreliable, many of these values were far elevated in comparison with those of normal individuals. Thus, we concluded that the cause of death was diabetic ketoacidosis. We also discuss the diagnostic problems of postmortem blood chemistry. PMID:9184021

Yamazaki, M; Ogura, Y; Wakasugi, C; Mitsukuni, Y; Yoshimura, M

1997-04-01

185

Phytocontact Dermatitis due to Mustard Seed Mimicking Burn Injury: Report of a Case  

PubMed Central

Mustard seeds have been used in traditional folk medicine as a stimulant, diuretic, and purgative and to treat a variety of ailments including peritonitis and neuralgia. Mustards are still used today in mustard plasters to treat rheumatism, arthritis, chest congestion, aching back, and sore muscles. To make a mustard plaster, mix equal parts of flour and powdered mustard and spread it as a paste on a doubled piece of soft cloth. Apply mustard plaster to the affected area for a maximum of 15 minutes. Prolonged application can result in burns to the skin and nerve damage. Skin lesions occur within hours after exposure, and there is no significant therapy procedure. This case report is about a patient with second-degree burn, occurred when a mixture including mustard seed was exposed to her skin in the pain therapy of the osteoarthritis in her left knee. There are no studies analyzing treatment of skin burns induced by mustard seed in the literature. While in this type of burns our experience is limited, we think that conservative approach should be first choice of treatment. PMID:22666267

Yabanoglu, Hakan; Akbulut, Sami; Karakayali, Feza

2012-01-01

186

Vertebral artery dissection due to an esophageal foreign body migration: a case report  

PubMed Central

Unintentional foreign bodies‘ swallowing is a fairly common occurrence in ENT consultation especially among children. They usually pass through the gastrointestinal tract without complications. Migration of a foreign body through the esophageal wall is rare. It represents about 1% to 4% of all cases of foreign bodies‘ ingestion. A 16 year's old female patient has presented to ENT emergency with a painful dysphagia following an accidental ingestion of a metallic pin. Cervical X ray confirmed the presence of the pin while endoscopic investigations have shown no foreign body. Cervical CT scan revealed the migration of the foreign body through the esophageal wall with left vertebral artery dissection. Endoscopic management has been sufficient with an uneventful post operative follow up. Esophageal foreign bodies are very diverse mainly dominated by fish bones (60%) and chicken bones (16%). Metallic pins are rare. The major risks of migration of those foreign bodies are cervical abscess, mediastinitis and oeso-vascular fistulae. Cases of self extrusion through the skin have been reported. Migration of a foreign body through the esophageal wall is rare. Endoscopic management has been sufficient. PMID:25018833

Benmansour, Najib; Ouattassi, Naouar; Benmlih, Amine; Elalami, Mohamed Noureddine

2014-01-01

187

Phytocontact Dermatitis due to Mustard Seed Mimicking Burn Injury: Report of a Case.  

PubMed

Mustard seeds have been used in traditional folk medicine as a stimulant, diuretic, and purgative and to treat a variety of ailments including peritonitis and neuralgia. Mustards are still used today in mustard plasters to treat rheumatism, arthritis, chest congestion, aching back, and sore muscles. To make a mustard plaster, mix equal parts of flour and powdered mustard and spread it as a paste on a doubled piece of soft cloth. Apply mustard plaster to the affected area for a maximum of 15 minutes. Prolonged application can result in burns to the skin and nerve damage. Skin lesions occur within hours after exposure, and there is no significant therapy procedure. This case report is about a patient with second-degree burn, occurred when a mixture including mustard seed was exposed to her skin in the pain therapy of the osteoarthritis in her left knee. There are no studies analyzing treatment of skin burns induced by mustard seed in the literature. While in this type of burns our experience is limited, we think that conservative approach should be first choice of treatment. PMID:22666267

Yabanoglu, Hakan; Akbulut, Sami; Karakayali, Feza

2012-01-01

188

Onset of complications following cervical manipulation due to malpractice in osteopathic treatment: a case report.  

PubMed

The aim of this study is to correlate cervical disc herniation with manipulation performed by a non-physician osteopath on a patient complaining of neck pain. The authors report a case in which a woman - treated with osteopathic spinal manipulation - developed cervical-brachial neuralgia following the cervical disc herniation. The patient then underwent surgery and was followed by physiotherapists. A clinical condition characterized by limitation of neck mobility, with pain and sensory deficit in the right arm and II-III fingers, still persists. The patient consulted the authors to establish whether cervical disc herniation could be attributed to manipulation. Adverse events or side effects of spinal manipulative therapy are relatively common and usually benign. Most of these side effects are mild or moderate, but sometimes they can be severe. Cervical manipulation can provoke complications less often than thoracic or lumbar manipulation. Furthermore, many diseases can be absolutely and relatively contraindicated to osteopathic treatment. Therefore, the knowledge of a patient's clinical conditions is essential before starting a manipulative treatment; otherwise the osteopath could be accused of malpractice. It is the authors' opinion that a cause-effect relationship exists between the manipulative treatment and the development of disc herniation. PMID:24402084

Cicconi, Michela; Mangiulli, Tatiana; Bolino, Giorgio

2014-10-01

189

Rhegmatogenous retinal detachment due to a macular hole in a patient with pars planitis: a case report.  

PubMed

We report a rare case of rhegmatogenous retinal detachment due to a full-thickness macular hole in a young patient with pars planitis. This study was an interventional case report. A 38-year-old Asian man presented with acute reduction of vision in his left eye. His past ocular history revealed a precedent of two intravitreal steroid injections in his left eye, and fundoscopy revealed a total bullous retinal detachment along with 360° snowbanking at the pars plana. Precise preoperative visualization of the posterior pole was impossible due to a dense nuclear cataract. During surgery, an unexpected full-thickness macular hole with no associated epiretinal membrane was observed, which resulted in the retinal detachment. This case of chronic pars planitis complicated with a full-thickness macular hole resulting in retinal detachment was successfully treated with vitrectomy, internal limiting membrane peeling, and perfluoropropane tamponade. Visual acuity improved from hand movements to 6/36 Snellen at 12 months postsurgery. This case report illustrates the rare but possible association between pars planitis with macular hole formation and subsequent retinal detachment, underlying the beneficiary outcome of vitrectomy surgery both diagnostically and therapeutically. PMID:25565856

Stavrakas, Panagiotis; Androu, Angeliki A; Tranos, Paris; Kontou, Evgenia; Milia, Maria; Georgalas, Ilias

2015-01-01

190

Rhegmatogenous retinal detachment due to a macular hole in a patient with pars planitis: a case report  

PubMed Central

We report a rare case of rhegmatogenous retinal detachment due to a full-thickness macular hole in a young patient with pars planitis. This study was an interventional case report. A 38-year-old Asian man presented with acute reduction of vision in his left eye. His past ocular history revealed a precedent of two intravitreal steroid injections in his left eye, and fundoscopy revealed a total bullous retinal detachment along with 360° snowbanking at the pars plana. Precise preoperative visualization of the posterior pole was impossible due to a dense nuclear cataract. During surgery, an unexpected full-thickness macular hole with no associated epiretinal membrane was observed, which resulted in the retinal detachment. This case of chronic pars planitis complicated with a full-thickness macular hole resulting in retinal detachment was successfully treated with vitrectomy, internal limiting membrane peeling, and perfluoropropane tamponade. Visual acuity improved from hand movements to 6/36 Snellen at 12 months postsurgery. This case report illustrates the rare but possible association between pars planitis with macular hole formation and subsequent retinal detachment, underlying the beneficiary outcome of vitrectomy surgery both diagnostically and therapeutically. PMID:25565856

Stavrakas, Panagiotis; Androu, Angeliki A; Tranos, Paris; Kontou, Evgenia; Milia, Maria; Georgalas, Ilias

2015-01-01

191

A report of iliac muscle abscess due to Mycobacterium bovis after bacillus Calmette-Guerin therapy for bladder cancer.  

PubMed

Bacillus Calmette-Guerin (BCG) vaccine is traditionally used for vaccination against tuberculosis. BCG vaccine contains live attenuated strain of Mycobacterium bovis. Intravesical BCG is also effective in treatment of transitional cell carcinoma of the urinary bladder. Complications after intravesical BCG immunotherapy are extremely rare. We report an iliac muscle abscess due to M bovis that developed 4 years after intravesical BCG therapy for bladder cancer. Infection with M bovis, though rare, should be considered in patients with prior BCG therapy for bladder cancer. PMID:20224496

Talluri, Siva K; Marigowda, Lokesh; Besur, Siddesh; Talluri, Jyothsna; Forstall, Gregory J

2010-04-01

192

Giant Urinary Bladder and Bilateral Giant Hydronephrosis due to Bladder Neck Obstruction: One Case Report and Literature Review  

PubMed Central

Bilateral hydronephrosis secondary to urinary obstruction leads to a buildup of back pressure in the urinary tract and may lead to impairment of renal function. Cases of giant hydronephrosis are rare and usually contain no more than 1-2 litres of fluid in the collecting system. Here, we report a rarely seen case with giant urinary bladder and bilateral giant hydronephrosis due to bladder neck obstruction which contains 4000?mL fluid in the collecting system of the kidney mimicking an ascites in an adult male. PMID:22606637

Tazi, Mohammed Fadl; Riyach, Omar; Ahallal, Youness; Mellas, Soufiane; Khallouk, Abdelhak; El Fassi, Mohammed Jamal; Farih, Moulay Hassan

2012-01-01

193

A unique cause of a rare disorder, unilateral macromastia due to lymphangiomatosis of the breast: a case report.  

PubMed

Macromastia and in particular unilateral macromastia is a rare clinical entity. It relates to massive enlargement of the breast in non-obese women. This case report describes an initially mild unilateral asymmetry occurring nine months postpartum in a 33-year-old female. However, following her second pregnancy within 12 months, her left breast became severely enlarged. This did not improve on delivery. No discrete lesion was seen on imaging and no significant abnormalities were seen in her blood chemistry. Surgical treatment was a mammoplasty and 580 g of mammary tissue was removed. Grossly, there was spongiform subcutaneous tissue with diffuse extension. On histology, this consisted of a highly complex and diffuse pattern of infiltration and of cavernous empty channels lined by a delicate attenuated endothelium which was CD34 and D2-40 positive. The appearances were consistent with lymphangiomatosis, more commonly encountered in the limbs, heretofore. Lymphangiomatosis has not been previously described in breast tissue and only a single case report exists for such a lesion in axillary tissue. Treatment of such lesions in the periphery by surgical excision is very difficult and excision without being radical can be impossible. Follow up of our patient, shows no evidence of recurrence in this patient. Our case report describes the clinicopathological features, differential diagnosis to be considered and treatment, in addition to reviewing the relevant literature. PMID:22730958

Hynes, Sean O; McLaughlin, Ray; Kerin, Michael; Rowaiye, Babatunde; Connolly, Charles E

2012-01-01

194

Acute Kidney Injury due to Menstruation-related Disseminated Intravascular Coagulation in an Adenomyosis Patient: A Case Report  

PubMed Central

The authors report a case of acute kidney injury (AKI) resulting from menstruation-related disseminated intravascular coagulation (DIC) in an adenomyosis patient. A 40-yr-old woman who had received gonadotropin for ovulation induction therapy presented with anuria and an elevated serum creatinine level. Her medical history showed primary infertility with diffuse adenomyosis. On admission, her pregnancy test was negative and her menstrual cycle had started 1 day previously. Laboratory data were consistent with DIC, and it was believed to be related to myometrial injury resulting from heavy intramyometrial menstrual flow. Gonadotropin is considered to play an important role in the development of fulminant DIC. This rare case suggests that physicians should be aware that gonadotropin may provoke fulminant DIC in women with adenomyosis. PMID:20808684

Son, Jungmin; Seong, Eun Young; Song, Sang Heon; Lee, Soo Bong; Kang, Jin; Yang, Byeong Yun; Lee, Su Jin; Choi, Jong-Ryeol; Lee, Kyu-Sup; Kwak, Ihm Soo

2010-01-01

195

When algorithms falter: a case report of a very small melanoma excised due to the dermatoscopic "ugly duckling" sign.  

PubMed

We present a case report of a 3.5 mm diameter superficial spreading melanoma on the upper back of a 27-year-old woman, signed out as Clark level 2, Breslow thickness 0.2 mm with regression to 0.45 mm. The patient, with Fitzpatrick type 1 skin and minimal actinic damage, had presented for a routine skin check with no previous history of skin cancers. At the age of 17 she had received chemotherapy and radiotherapy for Ewing's sarcoma of the right hip with pulmonary metastases. The skin lesion was assessed as dermatoscopically symmetrical and was not predicted as a melanoma by any algorithmic method. The provisional diagnosis of melanoma was made on the basis that this lesion was completely different in dermatoscopic pattern to her other nevi, a dermatoscopic "ugly duckling" lesion. We draw attention to the recently established link between defects in the STAG2 gene and Ewing's sarcoma, glioblastoma and melanoma. PMID:23785647

Inskip, Mike; Magee, Jill; Weedon, David; Rosendahl, Cliff

2013-04-01

196

Massive hemoptysis and complete unilateral lung collapse in pregnancy due to pulmonary tuberculosis with good maternal and fetal outcome: a case report  

PubMed Central

Background We report an extremely rare case of massive hemoptysis and complete left-sided lung collapse in pregnancy due to pulmonary tuberculosis in a health care worker with good maternal and fetal outcome. Case presentation A 33-year-old human immuno deficiency virus seronegative African health care worker in her fourth pregnancy with two previous second trimester miscarriages and an apparently healthy daughter from her third pregnancy presented coughing up copious amounts of blood at 18 weeks and two days of gestation. She had a cervical suture in situ for presumed cervical weakness. Computed tomography of her chest showed complete collapse of the left lung; subsequent bronchoscopy was apparently normal. Her serum ?-human chorionic gonadotropin, tests for autoimmune disease and echocardiography were all normal. Her lung re-inflated spontaneously. Sputum for acid alcohol fast bacilli was positive; our patient was commenced on anti-tuberculosis medication and pyridoxine. At 41 weeks and three days of pregnancy our patient went into spontaneous labor and delivered a live born female baby weighing 2.6 kg with APGAR scores of nine and 10 at one and five minutes respectively. She and her baby are apparently doing well about 10 months after delivery. Conclusion It is possible to have massive hemoptysis and complete unilateral lung collapse with spontaneous resolution in pregnancy due to pulmonary tuberculosis with good maternal and fetal outcome. PMID:23968230

2013-01-01

197

Irreducible dislocated total hip replacement due to intra-articular incarceration of bone cement: A case report  

PubMed Central

INTRODUCTION Dislocation following total hip replacement is a well-documented complication. We present an unusual cause of failure to achieve a concentric closed reduction of a cemented total hip replacement which has never previously been reported. PRESENTATION OF CASE A 78-year-old female patient had an unsuccessful closed reduction of a posteriorly dislocated total hip replacement. Careful review of perioperative radiographs revealed a fragment of bone cement incarcerated within the acetabular component blocking reduction. This was confirmed on a subsequent computed tomography scan. Open reduction via a posterior approach with retrieval of the cement fragment was eventually required. DISCUSSION Observation of important radiological features which may prevent unnecessary further attempts at closed reduction are discussed. We consider reasons for a non-concentric reduction and reflect on the dangers of multiple forced attempts. CONCLUSION This case emphasises the importance of clinical judgement during closed reduction and highlights a previously unreported cause for non-concentric reduction in a dislocated cemented total hip replacement. PMID:25460462

Lim, Hai Fon; Jain, Sameer; Haughton, Ben; Veysi, Veysi; Shaw, David

2014-01-01

198

Widespread infection of the Eastern red-spotted newt (Notophthalmus viridescens) by a new species of Amphibiocystidium, a genus of fungus-like mesomycetozoan parasites not previously reported in North America.  

PubMed

Given the worldwide decline of amphibian populations due to emerging infectious diseases, it is imperative that we identify and address the causative agents. Many of the pathogens recently implicated in amphibian mortality and morbidity have been fungal or members of a poorly understood group of fungus-like protists, the mesomycetozoans. One mesomycetozoan, Amphibiocystidium ranae, is known to infect several European amphibian species and was associated with a recent decline of frogs in Italy. Here we present the first report of an Amphibiocystidium sp. in a North American amphibian, the Eastern red-spotted newt (Notophthalmus viridescens), and characterize it as the new species A. viridescens in the order Dermocystida based on morphological, geographical and phylogenetic evidence. We also describe the widespread and seasonal distribution of this parasite in red-spotted newt populations and provide evidence of mortality due to infection. PMID:17931460

Raffel, T R; Bommarito, T; Barry, D S; Witiak, S M; Shackelton, L A

2008-02-01

199

Annoyance and self-reported sleep disturbance due to night-time railway noise examined in the field.  

PubMed

Railway noise interferes with daytime activities and disturbs sleep leading to annoyance of exposed residents. The main objective of this paper was to establish exposure-response relationships between nocturnal railway noise exposure and annoyance and to examine self-reported sleep disturbances as short-term reactions to noise. In a field study 33 residents living close to railway tracks in the Cologne/Bonn area (Germany) were investigated. Railway noise was measured indoors during nine consecutive nights at each site. Questionnaires referring to annoyance and non-acoustical factors were performed. Annoyance ratings increased significantly with the total number of trains and freight trains per night, and non-significantly with rising number of passenger trains and energy equivalent sound pressure level (L(Aeq)), when adjusting the model for non-acoustical variables. The total number of trains and the number of freight trains also significantly affected self-reported awakening frequency, but no other aspects of subjective sleep disturbances. The responses of this subject sample referring to railway noise in the previous night point to rather low impairments of exposed residents. PMID:23145596

Pennig, Sibylle; Quehl, Julia; Mueller, Uwe; Rolny, Vinzent; Maass, Hartmut; Basner, Mathias; Elmenhorst, Eva-Maria

2012-11-01

200

Case report: pharyngolaryngeal stenosis in a child due to caustic ingestion treated with transoral CO2 laser microsurgery.  

PubMed

Accidental caustic ingestion occurs mainly in the 2- to 3-year-old age group. Up to 33% of patients develop long-term complications that principally involve the gastroesophageal tract, whereas their occurrence at the level of pharyngeal and laryngeal structures is less frequent. When present, strictures are the main disorders that can be observed. In this pathological situation, surgery is the treatment of choice, and several procedures have been described. We report the history of a 3-year-old boy affected by pharyngolaryngeal stenosis due to accidental caustic ingestion. After careful diagnosis, the child underwent surgery by transoral CO2 laser. The patient had immediate improvement and restarted oral feeding 1 day after the surgical procedure. An analysis of diagnosis and treatment of this long-term complication is also presented. PMID:24944275

Berlucchi, Marco; Barbieri, Diego; Garofolo, Sabrina; Stefini, Stefania; Peretti, Giorgio

2014-12-01

201

Arthroscopic decompression of an entrapped suprascapular nerve due to an ossified superior transverse scapular ligament: a case report  

PubMed Central

Introduction Suprascapular neuropathy is an uncommon cause of shoulder pain and weakness and therefore is frequently misdiagnosed. As a consequence, misdiagnosis can include inappropriate conservative treatment or unsuccessful surgical procedure. Case presentation A rare case is reported of a 54-year-old woman who suffered from suprascapular nerve entrapment syndrome. The patient was subjected to arthroscopy of the left shoulder, where a compression of the suprascapular nerve due to an ossified superior transverse scapular ligament was diagnosed. The arthroscopic release of the suprascapular nerve brought relief from pain, weakness and atrophy of the supraspinatus and infraspinatus muscles. Conclusion Arthroscopic decompression of the entrapped suprascapular nerve is technically challenging, but less invasive and potentially a more effective way to treat suprascapular neuropathy, as it may provide a more rapid recovery, especially in the rare case that the nerve is depressed by an ossified superior transverse scapular ligament. PMID:19918464

Sergides, Neoptolemos N; Boukoros, Euangelos; Papagiannopoulos, George

2009-01-01

202

Critical ventriculo-peritoneal shunt failure due to peritoneal tuberculosis: Case report and diagnostic suggestions for abdominal pseudocyst  

PubMed Central

Background: Tuberculous peritonitis (TBP) is a well-known complication of ventriculo-peritoneal (VP) shunt treatment for hydrocephalus resulting from tuberculous meningitis (TBM). However, a case of hydrocephalus unrelated to TBM resulting from VP shunt malfunction due to TBP has not been reported. Case Description: A 21-year-old male presented with nausea, abdominal pain, and headache. VP and cysto-peritoneal (CP) shunts had been inserted to treat hydrocephalus due to a suprasellar arachnoid cyst, replaced the VP and removed the CP in his childhood. Computed tomography demonstrated acute hydrocephalus and an abdominal pseudocyst surrounding the distal end of the peritoneal tube. Initial laboratory data showed elevated white blood cell count and C-reactive protein level, but no causative pathogen was identified. External drainage of cerebrospinal fluid (CSF) and of the fluid in the peritoneal cyst was established, and empirical antibiotic therapy was initiated. Bacterial cultures eventually revealed Mycobacterium tuberculosis infection, and TBP was diagnosed. The patient responded well to antituberculosis (anti-TB) agents and insertion of a ventriculo-pleural shunt. Conclusion: This case highlights the possibility of CSF shunt failure and concomitant neurological sequelae from TB infection even when the pathogen has not invaded the central nervous system, as in TBM. Moreover, TBP is rare in developed countries and therefore may be misdiagnosed because of nonspecific clinical features and low sensitivity of common TB screening methods. PMID:24991474

Takase, Hajime; Tatezuki, Junya; Ikegaya, Naoki; Yamamoto, Daisuke; Hashimoto, Mizuki; Takagi, Makoto; Mochimatsu, Yasuhiko; Kawahara, Nobutaka

2014-01-01

203

Hypercortisolaemia due to ectopic adrenocorticotropic hormone secretion by a nasal paraganglioma: a case report and review of the literature  

PubMed Central

Background Adrenocorticotropic hormone-producing extraadrenal paragangliomas are extremely rare. We present a case of severe hypercortisolemia due to ectopic adrenocorticotropic hormone secretion by a nasal paraganglioma. Case presentation A 70-year-old Caucasian woman was emergently admitted to our department with supraventricular tachycardia, oedema of face and extremities and hypertensive crisis. Initial laboratory evaluation revealed severe hypokalemia and hyperglycemia without ketoacidosis, although no diabetes mellitus was previously known. Computed tomography revealed a large tumor obliterating the left paranasal sinus and a left-sided adrenal mass. After cardiovascular stabilisation, a thorough hormonal assessment was performed revealing marked adrenocorticotropic hormone-dependent hypercortisolism. Due to the presence of a cardiac pacemaker magnetic resonance imaging of the hypophysis was not possible. [68Ga-DOTA]-TATE-Positron-Emission-Tomography was performed, showing somatostatin-receptor expression of the paranasal lesion but not of the adrenal lesion or the hypophysis. The paranasal tumor was resected and found to be an adrenocorticotropic hormone-producing paraganglioma of low-proliferative rate. Postoperatively the patient became normokaliaemic, normoglycemic and normotensive without further need for medication. Genetic testing showed no mutation of the succinatdehydrogenase subunit B- and D genes, thus excluding hereditary paragangliosis. Conclusion Detection of the adrenocorticotropic hormone source in Cushing’s syndrome can prove extremely challenging, especially when commonly used imaging modalities are unavailable or inconclusive. The present case was further complicated by the simultaneous detection of two tumorous lesions of initially unclear biochemical behaviour. In such cases, novel diagnostic tools - such as somatostatin-receptor imaging - can prove useful in localising hormonally active neuroendocrine tissue. The clinical aspects of the case are discussed and relevant literature is reviewed. PMID:23958171

2013-01-01

204

Congenital Adrenal Hyperplasia due to 17-alpha-hydoxylase/17,20-lyase Deficiency Presenting with Hypertension and Pseudohermaphroditism: First Case Report from Oman.  

PubMed

This is the first report of congenital adrenal hyperplasia (CAH) due to combined 17?-hydroxylase/17,20 lyase deficiency in an Omani patient who was initially treated for many years as a case of hypertension. CAH is an uncommon disorder that results from a defect in steroid hormones biosynthesis in the adrenal cortex. The clinical presentation depends on the site of enzymatic mutations and the types of accumulated steroid precursors. A 22-year-old woman who was diagnosed to have hypertension since the age of 10 years who was treated with anti-hypertensive therapy was referred to the National Diabetes and Endocrine Centre, Royal Hospital, Oman. The patient also had primary amenorrhea and features of sexual infantilism. Full laboratory and radio-imaging investigations were done. Adrenal steroids, pituitary function and karyotyping study were performed and the diagnosis was confirmed by molecular mutation study. Laboratory investigations revealed adrenal steroids and pituitary hormones profile in addition to 46XY karyotype that are consistent with the diagnosis of CAH due to 17?-hydroxylase deficiency. Extensive laboratory workup revealed low levels of serum cortisol (and its precursors 17?-hydroxyprogesterone and 11-deoxycortisol), adrenal androgens (dehydroepiandrosterone sulfate and androstenedione), and estrogen (estradiol); and high levels of mineralocorticoids precursors (11-deoxycorticosterone and corticosterone) with high levels of ACTH, FSH and LH. Mutation analysis revealed CYP17A1-homozygous mutation (c.287G>A p.Arg96Gln) resulting in the complete absence of 17?-hydroxylase/17,20-lyase activity. The patient was treated with dexamethasone and ethinyl estradiol with cessation of anti-hypertensive therapy. A review of the literature was conducted to identify previous studies related to this subtype of CAH. This is the first biochemically and genetically proven case of CAH due to 17?-hydroxylase/17,20-lyase deficiency in Oman and in the Arab World described in the literature. PMID:24498484

Mula-Abed, Waad-Allah S; Pambinezhuth, Fathima B; Al-Kindi, Manal K; Al-Busaidi, Noor B; Al-Muslahi, Hilal N; Al-Lamki, Mohammad A

2014-01-01

205

Concentrations of APINACA, 5F-APINACA, UR-144 and its degradant product in blood samples from six impaired drivers compared to previous reported concentrations of other synthetic cannabinoids.  

PubMed

A large number of new psychoactive substances are available at the illicit drug market and the synthetic cannabinoids (SCs) are among the substances that have led to serious side effects and death. Knowledge about common concentrations of these drugs are however sparse. Concentrations of APINACA and 5F-APINACA in biological matrixes have previously not been reported, and concentrations of UR-144 and its degradant product in blood samples from driving under the influence of drug (DUID) cases have not been published. The aims of this study were to report concentrations of APINACA, 5F-APINACA, UR-144 and UR-144 degradant from DUID cases analyzed at the Norwegian Institute of Public Health (NIPH), and also previously unpublished concentrations of AM-2201 in cases from our Institute. We have further summarized all the former published studies where concentrations of SCs have been reported, to compare with the results from these newer SCs. In whole blood from one driver we have found 5F-APINACA and from three drivers both APINACA and 5F-APINACA in concentrations from 0.24 to 24.5 and 0.9 to 6.5?g/L, respectively, and UR-144 in two cases in concentrations of 0.22 and 0.47?g/L. UR-144 degradant in a concentration of 0.15?g/L was found in one of the cases. A summary of the literature reveals major deficiencies regarding concentrations of most of the SCs. The SCs most frequently detected in DUID cases were (n?8) AM-2201, JWH-122, JWH-018 and JWH-210. In intoxication cases AM-2201 (n=517) was the most often detected SC, followed by JWH-122, JWH-210, UR-144, JWH-018, and MAM-2201 (n>100). Four studies regarding concentrations in autopsy cases have been published, and concentrations of four different SCs have been reported (JWH-018, JWH-073, JWH-210, AM-2201 and the metabolites of AM-2201; 4-OH-pentyl, JWH-018 5-OH-pentyl and JWH-018 pentanoic acid). Pharmacokinetic data are only available for JWH-018 (n=3), JWH-073 (n=1) and the metabolites of AM-2201; 4-OH-pentyl, 6-OH-indole, JWH-018 5-OH-pentyl and JWH-018 pentanoic acid (n=1). PMID:25485949

Karinen, Ritva; Tuv, Silja Skogstad; Øiestad, Elisabeth Leere; Vindenes, Vigdis

2015-01-01

206

Parametric study of the potential for BWR ECCS strainer blockage due to LOCA generated debris. Final report  

SciTech Connect

This report documents a plant-specific study for a BWR/4 with a Mark I containment that evaluated the potential for LOCA generated debris and the probability of losing long term recirculation capability due ECCS pump suction strainer blockage. The major elements of this study were: (1) acquisition of detailed piping layouts and installed insulation details for a reference BWR; (2) analysis of plant specific piping weld failure probabilities to estimate the LOCA frequency; (3) development of an insulation and other debris generation and drywell transport models for the reference BWR; (4) modeling of debris transport in the suppression pool; (5) development of strainer blockage head loss models for estimating loss of NPSH margin; (6) estimation of core damage frequency attributable to loss of ECCS recirculation capability following a LOCA. Elements 2 through 5 were combined into a computer code, BLOCKAGE 2.3. A point estimate of overall DEGB pipe break frequency (per Rx-year) of 1.59E-04 was calculated for the reference plant, with a corresponding overall ECCS loss of NPSH frequency (per Rx-year) of 1.58E-04. The calculated point estimate of core damage frequency (per Rx-year) due to blockage related accident sequences for the reference BWR ranged from 4.2E-06 to 2.5E-05. The results of this study show that unacceptable strainer blockage and loss of NPSH margin can occur within the first few minutes after ECCS pumps achieve maximum flows when the ECCS strainers are exposed to LOCA generated fibrous debris in the presence of particulates (sludge, paint chips, concrete dust). Generic or unconditional extrapolation of these reference plant calculated results should not be undertaken.

Zigler, G.; Brideau, J.; Rao, D.V.; Shaffer, C.; Souto, F.; Thomas, W. [Science and Engineering Associates, Inc., Albuquerque, NM (United States)

1995-10-01

207

Case report: failure under azithromycin treatment in a case of bacteremia due to Salmonella enterica Paratyphi A  

PubMed Central

Background Limited information is available regarding the clinical efficacy of azithromycin for the treatment of enteric fever due to fluoroquinolone-resistant Salmonella Typhi and Salmonella Paratyphi among travelers returning to their home countries. Case presentation We report a case of a 52-year-old Japanese man who returned from India, who developed a fever of 39°C with no accompanying symptoms 10 days after returning to Japan from a 1-month business trip to Delhi, India. His blood culture results were positive for Salmonella Paratyphi A. He was treated with 14 days of ceftriaxone, after which he remained afebrile for 18 days before his body temperature again rose to 39°C with no apparent symptoms. He was then empirically given 500 mg of azithromycin, but experienced clinical and microbiological failure of azithromycin treatment for enteric fever due to Salmonella Paratyphi A. However, the minimum inhibitory concentration (MIC) of azithromycin was not elevated (8 mg/L). He was again given ceftriaxone for 14 days with no signs of recurrence during the follow-up. Conclusion There are limited data available for the treatment of enteric fever using azithromycin in travelers from developed countries who are not immune to the disease, and thus, careful follow-up is necessary. In our case, the low azithromycin dose might have contributed the treatment failure. Additional clinical data are needed to determine the rate of success, MIC, and contributing factors for success and/or failure of azithromycin treatment for both Salmonella Typhi and Salmonella Paratyphi infections. PMID:25041573

2014-01-01

208

When algorithms falter: a case report of a very small melanoma excised due to the dermatoscopic “ugly duckling” sign  

PubMed Central

We present a case report of a 3.5 mm diameter superficial spreading melanoma on the upper back of a 27-year-old woman, signed out as Clark level 2, Breslow thickness 0.2 mm with regression to 0.45 mm. The patient, with Fitzpatrick type 1 skin and minimal actinic damage, had presented for a routine skin check with no previous history of skin cancers. At the age of 17 she had received chemotherapy and radiotherapy for Ewing’s sarcoma of the right hip with pulmonary metastases. The skin lesion was assessed as dermatoscopically symmetrical and was not predicted as a melanoma by any algorithmic method. The provisional diagnosis of melanoma was made on the basis that this lesion was completely different in dermatoscopic pattern to her other nevi, a dermatoscopic “ugly duckling” lesion. We draw attention to the recently established link between defects in the STAG2 gene and Ewing’s sarcoma, glioblastoma and melanoma. PMID:23785647

Inskip, Mike; Magee, Jill; Weedon, David; Rosendahl, Cliff

2013-01-01

209

Mood disorder with mixed, psychotic features due to vitamin b12 deficiency in an adolescent: case report  

PubMed Central

Vitamin B12 is one of the essential vitamins affecting various systems of the body. Reports of psychiatric disorders due to its deficiency mostly focus on middle aged and elderly patients. Here we report a case of vitamin B 12 deficiency in a 16-year old, male adolescent who presented with mixed mood disorder symptoms with psychotic features. Chief complaints were “irritability, regressive behavior, apathy, crying and truancy” which lasted for a year. Premorbid personality was unremarkable with no substance use/exposure or infections. No stressors were present. The patient was not vegetarian. Past medical history and family history was normal. Neurological examination revealed glossitis, ataxia, rigidity in both shoulders, cog-wheel rigidity in the left elbow, bilateral problems of coordination in cerebellar examination, reduced swinging of the arms and masked face. Romberg’s sign was present. Laboratory evaluations were normal. Endoscopy and biopsy revealed atrophy of the gastric mucosa with Helicobacter Pylori colonization. Schilling test was suggestive of malabsorbtion. He was diagnosed with Mood disorder with Mixed, Psychotic Features due to Vitamin B12 Deficiency and risperidone 0.5?mg/day and intramuscular vitamin B12 500 mcg/day were started along with referral for treatment of Helicobacter pylori. A visit on the second week revealed no psychotic features. Romberg’s sign was negative and cerebellar tests were normal. Extrapyramidal symptoms were reduced while Vitamin B12 levels were elevated. Risperidone was stopped and parenteral Vitamin B12 treatment was continued with monthly injections for 3?months. Follow-up endoscopy and biopsy at the first month demonstrated eradication of H. pylori. He was followed monthly for another 6?months and psychiatric symptoms did not recur at the time of last evaluation. Despite limitations, this case may underline the observation that mood disorders with psychotic features especially with accompanying extrapyramidal symptoms lacking a clear etiology may be rare manifestation of vitamin B12 and/or folate deficiency in children and adolescents and be potentially amenable to treatment. PMID:22726236

2012-01-01

210

Cutaneous paragonimiasis due to triploid Paragonimus westermani presenting as a non-migratory subcutaneous nodule: a case report  

PubMed Central

Introduction Paragonimiasis is a food-borne infection caused by Paragonimus parasites. The lungs and pleura are the primary sites for the infection; however, ectopic infection can occur in other organs such as skin, liver and brain. It is difficult to make a diagnosis of ectopic paragonimiasis due to an ignorance of, and unfamiliarity with the disease. We report the case of a patient with subcutaneous paragonimiasis diagnosed by histopathological analysis and serological testing. Case presentation A 39-year-old Chinese immigrant woman presented with a subcutaneous nodule in her left lower back. The nodule was initially suspected of lipoma and she was followed up on without any treatment. However, it gradually indurated and the nodule was resected surgically. A magnetic resonance imaging scan revealed a polycystic lesion with inhomogeneous low or high intensity on T1- or T2-weighted images, respectively. The rim of the lesion was enhanced after contrast enhancement, but the inside did not show high-signal intensity. A histological analysis of the surgically resected specimen revealed variable-sized tubulo-cystic structures. The cyst wall showed a granulomatous change with scant eosinophilic infiltration. A number of parasite ova were observed in the necrotic tissue inside the cysts, and a parasite body with a presumed oral sucker and reproductive organ was also detected, suggesting a trematode infection. A subsequent serological examination showed a positive reaction of her serum to the Paragonimus westermani antigen. No abnormal findings were found on her chest computed tomography scan. The diagnosis of subcutaneous paragonimiasis caused by Paragonimus westermani was made. Conclusions We report a case presenting only as a non-migratory subcutaneous nodule without any pleuropulmonary lesion, which was initially suspected of lipoma but denied by magnetic resonance imaging scan results. The case was subsequently diagnosed as subcutaneous paragonimiasis from the results of histopathological analysis and serological testing. PMID:25322860

2014-01-01

211

Paraneoplastic secondary hypertension due to a renin-secreting desmoplastic small round cell tumor: A case report.  

PubMed

Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive malignancy with a poor outcome that occurs in adolescents and young adults; <200 cases of DSRCT have been reported. Renin-producing tumors are also rare and cases of extrarenal renin-producing tumors are even rarer. The present study describes the case of a 20-year-old male that was diagnosed with DSRCT and presented with severe hypertension and hypokalemia, as well as metabolic alkalosis. The plasma renin activity (PRA) level was identified to be markedly elevated (normal range in standing and supine positions, 1.3-4.0 ng/ml/h and 0.15-2.33 ng/ml/h, respectively) and the plasma aldosterone level was also increased (normal range in standing and supine positions, 4.0-31.0 ng/dl and 1.0-1.6 ng/dl, respectively). The symptoms of the patient were consistent with the renin-secreting tumor triad, which comprises hypertension, hypokalemia and elevated PRA. Paraneoplastic syndromes must always be considered in cancer patients exhibiting unusual clinical findings, despite their rarity. The current patient was diagnosed with paraneoplastic secondary hypertension due to the presence of disseminated renin-secreting DSRCT. The patient was treated with the VAC/IE regimen (vincristine, adriamycin, cyclophosphamide, ifosfamide and etoposide) for six cycles. Following this treatment, the serum renin and aldosterone levels fell to within the normal range and the patient's blood pressure was normalized without antihypertensive medication. Although an immunohistochemical evaluation of renin was not conducted as the sample size was inadequate, the present study demonstrated that the tumor had produced renin. The biosynthesis of renin was identified by the presence of mRNA that coded for the renin precursor, which was observed in the ascites of the patient. The current study describes, to the best of our knowledge, the first reported case of paraneoplastic secondary hypertension in a patient presenting with a renin-producing DSRCT. PMID:25289084

Lee, Hee-Jeong; Hyun, Jin-Soo; Jang, Hoe-Soo; Sul, Hyoung; Park, Sang-Gon

2014-11-01

212

Early onset frontotemporal dementia with psychiatric presentation due to the C9ORF72 hexanucleotide repeat expansion: a case report.  

PubMed

BackgroundFrontotemporal dementia (FTD) may present with psychiatric symptoms, usually together with neurological ones and in cases with a family history of dementia. We describe the case of a FTD behavioural variant with a psychiatric presentation and a normal neurological examination, due to a C9Orf72 gene mutation.Case presentationThe patient was a 57 years-old Caucasian woman with a recent onset of bizarre behaviours and mystic delusions. She had a negative clinical history for previous psychiatric disorders and treatments and this was her first admission to a Psychiatry Ward. A careful assessment was performed including, beyond psychiatric evaluation, the following: blood sampling, neurological examination (including electroencephalogram, electroencephalogram with zygomatic electrodes, Positron Emission Tomography, Cerebrospinal Fluid Analysis), carotid artery Doppler ultrasound, brain Magnetic Resonance Imaging ¿ angio Magnetic Resonance Imaging. Blood sampling for the genetic assessment of mutations associated to primary dementias was performed as well: the genes investigated were FUS, C9Orf72, PSEN-1, PSEN-2.ConclusionsSerological tests were negative, neurological examination was normal, instrumental examinations showed theta waves in the posterior temporal areas bilaterally and frontotemporal cortical atrophy bilaterally. The genetic assessment of mutations associated revealed she carried a GGGGCC hexanucleotide repeat expansion (at least 80 repeats) in C9Orf72 intron 1. Patients carrying the C9Orf72 mutation are likely to receive a psychiatric diagnosis (mainly mood disorder or schizophrenia) prior to correct diagnosis; this may be particularly problematic for those patients with no neurological signs to orientate diagnosis. Understanding the manner in which such FTD variant may present as a psychiatric syndrome, with a negative neurological examination, is essential to provide the best treatment for patients, as soon as possible, especially when the behavioural anomalies interfere with their care. PMID:25433797

Gramaglia, Carla; Cantello, Roberto; Terazzi, Emanuela; Carecchio, Miryam; D Alfonso, Sandra; Chieppa, Nunzia; Rizza, Maria; Zeppegno, Patrizia

2014-11-30

213

Reported foodborne outbreaks due to fresh produce in the United States and European union: trends and causes.  

PubMed

The consumption of fruit and vegetables continues to rise in the United States and European Union due to healthy lifestyle recommendations. Meanwhile, the rate of foodborne illness caused by the consumption of these products remains high in both regions, representing a significant public health and financial issue. This study addresses the occurrence of reported foodborne outbreaks associated with fresh fruits and vegetables consumption in the United States and European Union during the period 2004-2012, where data are available. Special attention is paid to those pathogens responsible for these outbreaks, the mechanisms of contamination, and the fresh produce vehicles involved. Norovirus is shown to be responsible for most of the produce-related outbreaks, followed by Salmonella. Norovirus is mainly linked with the consumption of salad in the United States and of berries in the European Union, as demonstrated by the Multiple Correspondence Analysis (MCA). Salmonella was the leading cause of multistate produce outbreaks in the United States and was the pathogen involved in the majority of sprouts-associated outbreaks. As is reflected in the MCA, the pattern of fresh produce outbreaks differed in the United States and European Union by the type of microorganism and the food vehicle involved. PMID:25587926

Callejón, Raquel M; Rodríguez-Naranjo, M Isabel; Ubeda, Cristina; Hornedo-Ortega, Ruth; Garcia-Parrilla, M Carmen; Troncoso, Ana M

2015-01-01

214

Small bowel obstruction due to an unconjugated ursodeoxycholic acid enterolith following living donor liver transplantation: Report of a case.  

PubMed

We report an unusual case of small bowel obstruction due to an ursodeoxycholic acid (UDCA) enterolith that occurred 7?years after liver transplantation. A 70-year-old man had undergone multiple operations, including a living donor liver transplantation (LDLT) and hepaticojejunostomy. Four years after the LDLT, cholestasis developed, for which oral UDCA was administrated. Seven years after the LDLT, he was admitted to our hospital because of pneumonia; intestinal obstruction occurred following its resolution. A radiographic contrast study and computed tomographic scan indicated a movable mass as the cause of the ileus, suggesting a giant stone. We were unable to observe or remove the stone by double balloon enteroscopy owing to the presence of severe adhesion; thus, we surgically removed the mass. The patient's postoperative course was uneventful. He was discharged 20?days after the operation. An infrared spectrophotometric analysis revealed that the stone was a true enterolith, primarily composed of unconjugated UDCA. An ileus caused by a true enterolith is a rare clinical complication of LDLT. Nevertheless, it must be considered in the differential diagnosis of intestinal obstructions in liver transplant recipients with Roux-en-Y hepaticojejunostomies and/or bowel stasis. PMID:25091893

Mukai, Shoichiro; Onoe, Takashi; Tashiro, Hirotaka; Ohdan, Hideki

2014-08-01

215

Previous Thursday Tours Summer 2011  

E-print Network

Previous Thursday Tours Summer 2011 Exploring Historical DeKalb County July 14, 2011 ­ Glidden, 2011 ­ Sycamore Historical Museum August 4, 2011 ­ Sandwich Opera House and Stone Mill Museum Summer Hall July 29, 2010 ­ Early NIU Summer 2009 Exploring NIU July 9, 2009 ­ The Avalon Quartet

Kostic, Milivoje M.

216

Previous Thursday Tours Summer 2013  

E-print Network

Previous Thursday Tours Summer 2013 Something Old, Something New July 11 ­ Kishwaukee College July Department & the DeKalb County Community Foundation Summer 2012 Explore the Great Outdoors July 12 and Natural Resource Center August 2 ­ Prairie Oaks Forest Preserve Summer 2011 Exploring Historical De

Kostic, Milivoje M.

217

Paraneoplastic secondary hypertension due to a renin-secreting desmoplastic small round cell tumor: A case report  

PubMed Central

Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive malignancy with a poor outcome that occurs in adolescents and young adults; <200 cases of DSRCT have been reported. Renin-producing tumors are also rare and cases of extrarenal renin-producing tumors are even rarer. The present study describes the case of a 20-year-old male that was diagnosed with DSRCT and presented with severe hypertension and hypokalemia, as well as metabolic alkalosis. The plasma renin activity (PRA) level was identified to be markedly elevated (normal range in standing and supine positions, 1.3–4.0 ng/ml/h and 0.15–2.33 ng/ml/h, respectively) and the plasma aldosterone level was also increased (normal range in standing and supine positions, 4.0–31.0 ng/dl and 1.0–1.6 ng/dl, respectively). The symptoms of the patient were consistent with the renin-secreting tumor triad, which comprises hypertension, hypokalemia and elevated PRA. Paraneoplastic syndromes must always be considered in cancer patients exhibiting unusual clinical findings, despite their rarity. The current patient was diagnosed with paraneoplastic secondary hypertension due to the presence of disseminated renin-secreting DSRCT. The patient was treated with the VAC/IE regimen (vincristine, adriamycin, cyclophosphamide, ifosfamide and etoposide) for six cycles. Following this treatment, the serum renin and aldosterone levels fell to within the normal range and the patient’s blood pressure was normalized without antihypertensive medication. Although an immunohistochemical evaluation of renin was not conducted as the sample size was inadequate, the present study demonstrated that the tumor had produced renin. The biosynthesis of renin was identified by the presence of mRNA that coded for the renin precursor, which was observed in the ascites of the patient. The current study describes, to the best of our knowledge, the first reported case of paraneoplastic secondary hypertension in a patient presenting with a renin-producing DSRCT. PMID:25289084

LEE, HEE-JEONG; HYUN, JIN-SOO; JANG, HOE-SOO; SUL, HYOUNG; PARK, SANG-GON

2014-01-01

218

TESTING AND ANALYSIS OF CAP CONCRETE STRESS AND STRAIN DUE TO SHRINKAGE, CREEP, AND EXPANSION FINAL REPORT  

SciTech Connect

In-situ decommissioning of Reactors P- and R- at the Savannah River Site will require filling the reactor vessels with a special concrete based on materials such as magnesium phosphate, calcium aluminate or silica fume. Then the reactor vessels will be overlain with an 8 ft. thick layer of Ordinary Portland Cement (OPC) steel reinforced concrete, called the 'Cap Concrete'. The integrity of this protective layer must be assured to last for a sufficiently long period of time to avoid ingress of water into the reactor vessel and possible movement of radioactive contamination into the environment. During drying of this Cap Concrete however, shrinkage strains are set up in the concrete as a result of diffusion and evaporation of water from the top surface. This shrinkage varies with depth in the poured slab due to a non-uniform moisture distribution. This differential shrinkage results in restraint of the upper layers with larger shrinkage by lower layers with lesser displacements. Tensile stresses can develop at the surface from the strain gradients in the bulk slab, which can lead to surface cracking. Further, a mechanism called creep occurs during the curing period or early age produces strains under the action of restraining forces. To investigate the potential for surface cracking, an experimental and analytical program was started under TTQAP SRNL-RP-2009-01184. Slab sections made of Cap Concrete mixture were instrumented with embedded strain gages and relative humidity sensors and tested under controlled environmental conditions of 23 C and relative humidities (RH) of 40% and 80% over a period of 50 days. Calculation methods were also developed for predictions of stress development in the full-scale concrete placement over the reactor vessels. These methods were evaluated by simulating conditions for the test specimens and the calculation results compared to the experimental data. A closely similar test with strain gages was performed by Kim and Lee for a concrete mixture that did not employ humidity sensors and the admixtures used in this program. Yuan and Wan tried to predict the shrinkage strains and stresses in the Kim and Lee experiment, but did not include a creep analysis. Grasley and Lange conducted full restraint load tests on a concrete prism instrumented with humidity sensors over a 7 day curing period. The hypothetical case of full-scale placement of the Cap Concrete was also analyzed using the developed analytical methods. The calculation performed in this report is for scoping purposes only.

Guerrero, H.; Restivo, M.

2011-08-01

219

Heroin Addicts Reporting Previous Heroin Overdoses Also Report Suicide Attempts  

ERIC Educational Resources Information Center

Nonfatal heroin overdoses and suicide attempts are both common among heroin addicts, but there is limited knowledge about the association between them. The sample in the present study consisted of 149 regular heroin users in Malmo, Sweden. Out of these 98 had taken an unintentional heroin overdose at some time and 51 had made at least one attempt…

Bradvik, Louise; Frank, Arne; Hulenvik, Per; Medvedeo, Alvaro; Berglund, Mats

2007-01-01

220

Central Anticholinergic Syndrome due to Hypoxia-Induced Bradycardia in a Child with Difficult Intubation Undergoing Complete Dental Restoration: A Case Report  

PubMed Central

Central anticholinergic syndrome (CAS) following general anesthesia (GA) is a well known syndrome in children and adults. Many cases of CAS have been previously reported in the literature. However, there are only two reports of post resuscitation CAS after administration of small doses of atropine. Hereby, we report a case of CAS in a child undergoing complete dental restoration under GA after receiving a small dose of atropine to reverse hypoxia induced bradycardia. Intraoperative events such as hypoxia or cardiac arrest may play a role as triggers for CAS. However, we cannot establish a causal relationship between the occurrence of CAS and such critical events. PMID:25628689

Gharavifard, Mohamad; Razavi, Majid; Ghandehari Motlagh, Mehdi; Ziyaeifard, Mohsen

2014-01-01

221

Vaginal perforation due to jet ski accident.  

PubMed

A case of full thickness vaginal perforation into the peritoneal cavity resulting from a jet-skiing accident is presented. Attention is drawn to the previously reported cases of similar injuries due to high speed water sports, and the need for adequate protective clothing in all people undertaking such sports. PMID:2082899

Wein, P; Thompson, D J

1990-11-01

222

High prevalence in Switzerland of pure red-cell aplasia due to anti-erythropoietin antibodies in chronic dialysis patients: report of five cases  

Microsoft Academic Search

Background. Pure red-cell aplasia (PRCA) after eryth- ropoietin (Epo) administration due to the appearance of neutralizing anti-Epo antibodies has been reported in over 200 cases between 1998 and 2002. However, large intercountry disparities were observed in the occurrence of this syndrome. Methods. On behalf of the Swiss Society of Nephrology, a survey was conducted in all the dialysis units of

Carlo Schonholzer; Gerald Keusch; Luzia Nigg; Dominique Robert; Jean-Pierre Wauters

223

Conjunctivitis Due to Chlamydophila felis (Chlamydia psittaci Feline Pneumonitis Agent) Acquired From a Cat: Case Report with Molecular Characterization of Isolates from the Patient and Cat  

Microsoft Academic Search

Conjunctivitis due to Chlamydiaceae other than Chlamydia trachomatis is rarely reported because of infrequent occurrence or inadequate investigation. A case of chronic non-trachomatis chlamydial conjunctivitis is described. After full clinical information was supplied to the laboratory, a non-trachomatis chlamydia was recovered from the patient's eye. This organism, and a subsequent isolate from one of the patient's cats, were shown to

J. C. Hartley; S. Stevenson; A. J. Robinson; J. D. Littlewood; C. Carder; J. Cartledge; C. Clark; G. L. Ridgway

2001-01-01

224

Cervical spinal cord compression due to an osteochondroma in hereditary multiple exostosis: case report and review of the literature  

Microsoft Academic Search

BackgroundHereditary multiple exostosis is a benign disorder characterized by multiple osteochondromas affecting long and flat bones, although occasionally vertebral column involvement can be seen. Cervical spinal cord compression in HME is a rare condition. The objective of this manuscript is to describe a rare case of cervical myelopathy due to an exostosis arising from C7 in a patient with HME

Miguel Giudicissi-Filho; Carlos Vanderlei M. de Holanda; Luis Alencar B. Borba; Aziz Rassi-Neto; Carlos Alberto A. Ribeiro; Jean Gonçalves de Oliveira

2006-01-01

225

Acute-on-chronic liver failure due to thiamazole in a patient with hyperthyroidism and trilogy of Fallot: case report  

Microsoft Academic Search

BACKGROUND: Thiamazole is a widely used antithyroid agent that has been approved for the treatment of hyperthyroidism. Although thiamazole-induced hepatotoxicity is a main side effect, it may progress to liver failure in a very few cases. CASE PRESENTATION: We described a 24-year-old patient with hyperthyroidism and trilogy of Fallot, who developed liver failure due to thiamazole. Liver biopsy showed intrahepatic

Chuan Shen; Cai-Yan Zhao; Fang Liu; Ya-Dong Wang; Jun Yu

2010-01-01

226

Encephalomyelitis due to Cryptococcus neoformans var gattii presenting as spinal tumour: case report and review of the literature  

PubMed Central

A 24 year old immunocompetent German resident is described who developed multifocal encephalomyelitis due to infection with Cryptococcus neoformans var gatti, commonly considered a disease of tropical regions. In the light of current knowlege on the epidemiology of C neoformans var gatti and the travel history of the patient it is assumed that the infection was aquired outside Europe. As exclusive intramedullary involvement is an outstandingly rare manifestation in spinal cryptococcosis, the particular diagnostic procedure and the therapeutic stratagies are discussed?? PMID:11118259

Grosse, P; Tintelnot, K; Sollner, O; Schmitz, B

2001-01-01

227

Evaluation of flow redistribution due to flow blockage in rod bundles using COBRA code simulation. Final report. [PWR  

Microsoft Academic Search

During a Loss-of-Coolant Accident, fuel rod cladding may reach temperatures approaching 2200°F. At these temperatures, swelling and rupture of the cladding may occur. The resulting flow blockage will affect steam flow and heat transfer in the bundle during the period of reflooding. The COBRA-IV-I subchannel computer code was used to simulate flow redistribution due to sleeve blockages in the FLECHT-SEASET

D. A. Prelewicz; M. A. Caruso

1981-01-01

228

Proposal Due: _________________________ Senior Project Due: _________________________  

E-print Network

Proposal Due: _________________________ HURCA & Senior Project Due: _________________________ Priorities: Senior Project Guide #12;2 The Honors College Senior Project Guide Why Research? Research the communication and critical thinking skills necessary for graduate school and professional employment. Honors

Huang, Haiying

229

Acute jejunoileal obstruction due to a pseudopolyp in a child with undiagnosed crohn disease: A case report  

PubMed Central

Introduction Crohn's disease (CD) can affect any part of the alimentary tract from the mouth to the anus, with most common site being the terminal ileum. Case presentation A child suffering from undiagnosed Crohn disease (CD), presented with an acute abdominal obstruction due to a large pseudopolyp in the jejunoileal area. At laparotomy, a jejunoileal segment of 45 cm, containing multiple areas of damage to the small intestine, was excised and a primary end – to – end anastomosis was performed. Conclusion The coexistence of an intestinal pseudopolyp with undiagnosed Crohn's disease may be the cause of acute abdominal obstruction in children. PMID:18289386

Christianakis, Efstratios; Pashalidis, Nikolaos; Kokkinou, Stavroula; Pitiakoudis, Michael; Mplevrakis, Evangelos; Chorti, Maria; Rizos, Spiros; Filippou, Dimitrios

2008-01-01

230

Unilateral hemothorax in a 46 year old South Indian male due to a giant arteriovenous hemodialysis fistula: a case report.  

PubMed

In a patient undergoing regular hemodialysis through an arteriovenous fistula access, pleural effusion is a known long term complication. However, a unilateral hemothorax is relatively uncommon. Here we report a 46 year old male, end-stage renal disease patient, on maintenance hemodialysis, who presented with a giant brachiocephalic AV fistula in his left arm and progressive breathlessness. Radiological imaging revealed a left sided pleural effusion. Ultrasound guided aspiration revealed a hemorrhagic pleural fluid. A Doppler study of the fistula revealed a high velocity blood flow through the fistula, thereby establishing the cause of the unilateral hemothorax. Ligation of the fistula resulted in complete resolution of the hemothorax. The other possible causes for hemothorax in a dialysis patient are also discussed in this case report. PMID:18840271

Salim, Shihas; Ganeshram, Prasanthi; Patel, Amish Dilip; Kumar, Anita A; Vemuri, Divya; Jeyachandran, Vijay; Rajamanickam, Deepan; Shantha, Ghanshyam Palamaner Subash

2008-01-01

231

Avulsion fracture of the extensor carpi radialis longus carpal insertion due to a basketball injury: Case report and literature review.  

PubMed

Articular fractures of the base of the 2nd metacarpal involving the extensor carpi radialis longus insertion are unusual and poorly understood. There is no consensus as to how these fractures should be treated. We report the case of a 2nd metacarpal base fracture in a professional basketball player that was treated surgically with open reduction and internal fixation using cannulated screws. The management of this case is compared to similar cases in the literature. PMID:25284743

Robert, N; Zbili, D; Bellity, J; Doursounian, L; Mauprivez, R

2014-12-01

232

Chylous ascites and chylothorax due to constrictive pericarditis in a patient infected with HIV: a case report  

PubMed Central

Introduction Chylothorax and chylous ascites are uncommon and usually associated with trauma or neoplasms. To the best of our knowledge, constrictive pericarditis leading to chylothorax and chylous ascites in a person infected with HIV has never previously been described. Case presentation A 39-year-old Thai man was referred to our institute with progressive dyspnea, edema and abdominal distension. His medical history included HIV infection and pulmonary tuberculosis that was complicated by tuberculous pericarditis and cardiac tamponade. Upon further investigation, we found constrictive pericarditis, chylothorax and chylous ascites. A pericardiectomy was performed which resulted in gradual resolution of the ascites and chylous effusion. Conclusions Although constrictive pericarditis is an exceptionally rare cause of chylothorax and chylous ascites, it should nonetheless be considered in the differential diagnosis as a potentially reversible cause. PMID:22738274

2012-01-01

233

Duplication of 20qter and deletion of 20pter due to paternal pericentric inversion: patient report and review of 20qter duplications.  

PubMed

Duplications of the terminal long arm of chromosome 20 are rare chromosomal anomalies. We report a male infant found on array comparative genomic hybridization analysis to have a 19.5 Mb duplication of chromosome 20q13.12-13.33, as well as an 886 kb deletion of 20p13 at 18,580-904,299 bp. This anomaly occurred as the recombinant product of a paternal pericentric inversion. There have been 23 reported clinical cases involving 20qter duplications; however, to our knowledge this is only the second reported patient with a paternal pericentric inversion resulting in 46,XY,rec(20)dup(20q). This patient shares many characteristics with previously described patients with 20qter duplications, including microphthalmia, anteverted nares, long ears, cleft palate, small chin, dimpled chin, cardiac malformations, and normal intrauterine growth. While there is variable morbidity in patients with terminal duplications of 20q, a review of previously reported patients and comparison to our patient's findings shows significant phenotypic similarity. PMID:24954807

Starr, Lois J; Truemper, Edward J; Pickering, Diane L; Sanger, Warren G; Olney, Ann Haskins

2014-08-01

234

Cervical nystagmus due to loss of cerebellar inhibition on the cervico-ocular reflex: a case report.  

PubMed Central

Studies of the cervico-ocular reflex and the vestibulo-ocular reflex have been carried out separately and in combination on a patient with gait ataxia due to a cerebellar tumour. With the head fixed in space, body rotation to the right (left neck torsion) induced marked nystagmus to the left in darkness. Vestibulo-ocular responses to sinusoidal rotation were symmetrical while the neck was immobilised and asymmetric when it moved freely. It is suggested that the cervical nystagmus seen in this case was the result of removal of cerebellar inhibition upon the cervico-ocular reflex and that abnormal interaction of cervical and vestibular inputs could have played a role in the patient's unsteadiness. Images PMID:3872343

Bronstein, A M; Hood, J D

1985-01-01

235

Congenital fibrosis of extraocular muscle type 1A due to KIF21A mutation: first case report from Hong Kong.  

PubMed

With the advancement of ophthalmological genetics, the molecular basis for more and more eye diseases can be elucidated. Congenital fibrosis of extraocular muscle (CFEOM) is an example. It is characterised by a congenital non-progressive restrictive ophthalmoplegia and ptosis. It is an autosomal dominant disease, caused by mutations of the KIF21A gene. With positive family history and typical ophthalmological findings, mutational analysis of KIF21A gene should be performed, not only to confirming the diagnosis, but also to offer a prognosis, for genetic counselling, and the possibility of prenatal diagnosis. Here we report the first KIF21A mutation associated with CFEOM1A in Hong Kong. PMID:23535681

Luk, H M; Lo, Ivan F M; Lai, Carmen W S; Ma, Louis C K; Tong, Tony M F; Chan, Daniel H C; Lam, Stephen T S

2013-04-01

236

Spinal cord compression due to undiagnosed thoracic meningioma following lumbar surgery in an elderly patient: a case report.  

PubMed

As spinal surgery in elderly patients is becoming increasingly frequent, comorbidities likely to be decompensated after such procedures must be kept in mind. We report here the case of an 82-year-old woman who presented rapidly progressive spinal cord compression following lumbar surgery for radiculopathy. Investigations showed a thoracic intradural extramedullary compressive lesion, which after removal turned out to be a meningioma. We suggest that radiculopathy and non-specific degenerative modifications partially masked this lesion, and that lumbar surgery caused this acute neurological deterioration. Therefore, we advice caution in older patients among whom such ambiguous clinical presentation is frequent. PMID:24210294

Knafo, S; Lonjon, G; Vassal, M; Bouyer, B; Lonjon, N

2013-12-01

237

Rupture of the flexor digitorum superficialis at the musculotendinous junction due to a forearm fracture: a case report.  

PubMed

We present a case of a closed distal-third forearm fracture, in which the flexor digitorum superficialis was found ruptured at its musculotendinous junction. We diagnosed the ruptured tendon during the exploration of the ulnar nerve for observed preoperative palsy. Although there are numerous reports about avulsions at the bony insertions, there are very few about avulsion at the musculotendinous junction in the literature. This consideration leads to the conclusion that this kind of rupture may be more frequent than recognized. PMID:25077050

Fandridis, Emmanouil M; Dimou, Leonidas; Stavropoulos, Spiros; Fernandez, Diego L

2014-05-01

238

Tetany due to hypoparathyroidism as the initial manifestation of autoimmune polyendocrine syndrome type-2: A case report  

PubMed Central

Hypoparathyroidism is most commonly isolated and idiopathic. Hypoparathyroidism in autoimmune polyendocrine syndrome type-2 (APS-2) is extremely rare with few isolated reports and usually presents late. We present perhaps for the first time, hypoparathyroidism being the initial manifestation of APS-2 which was diagnosed in a 32 year lady with tingling of the extremities along with hypocalcemic tetany for 15 years. She also had generalized acral and mucosal hyperpigmentation of 2 years duration. Investigations were significant for low calcium (7.1mg/dl), elevated phosphorus (4.8mg/dl), vitamin-D insufficiency (27.4ng/ml), low intact parathyroid hormone (2.3pg/ml), low basal (4.7mcg/dl) and stimulated serum cortisol (9.2mcg/dl at half hour, 11.4mcg/dl at 1 hour post synacthen), elevated triiodothyronine (2.1ng/ml) and free tetraiodothyronine (2.4ng/dl) along with suppressed TSH (<0.005 U/L). Imaging relevaled mild cerebellar calcification, normal adrenals with diffuse uptake of Tc99- pertechnate. A diagnosis of hypoparathyroidism with Addison's and Graves’ disease as a part of APS-2 was made. This report intends to highlight the clinical heterogeneity and varied presentation of APS-2. Routine screening of other hormonal function (especially adrenal function, thyroid function and blood glucose) in a patient with diagnosed hypoparathyroidism is advisable to decrease the chances of missing APS-2. PMID:23565477

Dutta, Deep; Maisnam, Indira; Ghosh, Sujoy; Dasgupta, Ranen; Mukhopadhyay, Satinath; Chowdhury, Subhankar

2012-01-01

239

Successful radiofrequency catheter ablation of atrioventricular nodal reentrant tachycardia in a patient with dextrocardia due to unilateral pulmonary agenesis: a case report  

PubMed Central

Radiofrequency catheter ablation of the slow pathway is considered to be the treatment of choice for patients with atrioventricular nodal reentrant tachycardia. We report a 34-year-old female with mirror image dextrocardia due to unilateral pulmonary agenesis who underwent successful slow pathway ablation for typical atrioventricular nodal reentrant tachycardia. Using contrast injection, cardiac anatomy was identified in a short time and successfully ablated. PMID:25674017

Aksu, Tolga; Guler, Tumer Erdem; Golcuk, Ebru; Erden, Ismail; Ozcan, Kaz?m Serhan

2015-01-01

240

Recurrent Meningitis and Subarachnoid Hemorrhage Due to Salmonella in an HIV+ Patient: Case Report and Mini-Review of the Literature  

PubMed Central

Meningitis due to non-typhi salmonella is infrequent in HIV-positive adults. We report a case of a patient with >300 CD4+ cells/mm3 who presented with five episodes of recurrent meningitis, focal subarachnoid hemorrhage and cerebral vasculitis ultimately attributed to Salmonella choleraesuis infection. Even within the cART era invasive salmonellosis can occur in unusual ways in HIV-infected patients. PMID:21772932

Belloso, Waldo H; Romano, Marina; Greco, Graciela S; Davey, Richard T; Perelsztein, Ariel G; Sánchez, Marisa L; Ajzenszlos, Martín R; Otegui, Inés M

2011-01-01

241

Case report of a near medical event in stereotactic radiotherapy due to improper units of measure from a treatment planning system  

SciTech Connect

Purpose: The authors hereby notify the Radiation Oncology community of a potentially lethal error due to improper implementation of linear units of measure in a treatment planning system. The authors report an incident in which a patient was nearly mistreated during a stereotactic radiotherapy procedure due to inappropriate reporting of stereotactic coordinates by the radiation therapy treatment planning system in units of centimeter rather than in millimeter. The authors suggest a method to detect such errors during treatment planning so they are caught and corrected prior to the patient positioning for treatment on the treatment machine. Methods: Using pretreatment imaging, the authors found that stereotactic coordinates are reported with improper linear units by a treatment planning system. The authors have implemented a redundant, independent method of stereotactic coordinate calculation. Results: Implementation of a double check of stereotactic coordinates via redundant, independent calculation is simple and accurate. Use of this technique will avoid any future error in stereotactic treatment coordinates due to improper linear units, transcription, or other similar errors. Conclusions: The authors recommend an independent double check of stereotactic treatment coordinates during the treatment planning process in order to avoid potential mistreatment of patients.

Gladstone, D. J.; Li, S.; Jarvis, L. A.; Hartford, A. C. [Division of Radiation Oncology, Department of Medicine, Dartmouth-Hitchcock Medical Center, Norris Cotton Cancer Center, Lebanon, New Hampshire 03756 (United States); Division of Radiation Oncology, Department of Medicine, Dartmouth-Hitchcock Medical Center, Norris Cotton Cancer Center, Lebanon, New Hampshire 03756 and Department of Radiation Oncology, Temple University Hospital, Philadelphia, Pennsylvania 19104 (United States); Division of Radiation Oncology, Department of Medicine, Dartmouth-Hitchcock Medical Center, Norris Cotton Cancer Center, Lebanon, New Hampshire 03756 (United States)

2011-07-15

242

Successful percutaneous treatment for massive hemorrhage due to infectious pseudoaneurysm in the abdominal wall after percutaneous endoscopic gastrostomy: a case report  

PubMed Central

Background Percutaneous endoscopic gastrostomy (PEG) is often performed for alimentation and to prevent weight loss in patients with feeding problems due to central neurologic diseases such as cerebral infarction or intracranial hemorrhage. Although infection at the skin site after PEG placement is a typical late complication of PEG, a ruptured infectious pseudoaneurysm caused massive bleeding adjacent to the tract is rare. Prompt treatment is required to avoid the hemorrhage shock, however surgical ligation is difficult to obtain the arrest of bleeding in damaged skin due to the infection. Case presentation A 70-year-old male was bedridden due a cerebral infarction suffered 1 year previously. APEG was placed because of feeding problems, and a push-type, 20-Fr gastrostomy tube was inserted through the anterior abdominal wall. On day 16 after PEG placement, the patient had massive bleeding from the PEG site due to the rupture of infectious pseudoaneurysm and developed a decreased level of consciousness and hypotension. Treatment by percutaneous direct injection of a mixture of n-butyl-cyanoacrylate (NBCA)-lipiodol was performed and achieved good hemostasis is obtained. Conclusions A rare case of an infectious pseudoaneurysm that developed in the abdominal wall and caused massive bleeding at a PEG placement site was described. Percutaneous injection of a mixture of n-butyl-cyanoacrylate (NBCA)-lipiodol under ultrasound guidance is an effective treatment in this case. PMID:24915936

2014-01-01

243

Penis auto-amputation and chasm of the lower abdominal wall due to advanced penile carcinoma: a case report  

PubMed Central

Introduction Penile cancer is uncommon. When penile cancer is left untreated, at an advanced stage it can have tragic consequences for the patient. Case presentation Our case report does not concern a new manifestation of penile cancer, but an interesting presentation with clinical significance that emphasizes the need to diagnose and treat penile cancer early. It is an unusual case of a neglected penile cancer in a 57-year-old Greek man that led to auto-amputation of the penis and a large chasm in the lower abdominal wall. The clinical staging was T4N3M0 and our patient was treated with a bilateral cutaneous ureterostomy, chemotherapy and radiotherapy. Our patient died 18 months after his first admission in our clinic. Conclusions Emphasis must be placed on early diagnosis and treatment of penile cancer, so further development of the disease can be prevented. PMID:22152757

2011-01-01

244

Fulminant systemic capillary leak syndrome due to C1 inhibitor deficiency complicating acute dermatomyositis: a case report  

PubMed Central

Introduction Dermatomyositis is a chronic inflammatory disorder characterized by muscular and dermatologic symptoms with variable internal organ involvement. This is the first report on a patient with acute dermatomyositis and fulminant systemic capillary leak syndrome. Case presentation A 69-year-old Caucasian woman with chronic dermatomyositis presented with clinical signs of severe hypovolemic shock and pronounced hemoconcentration (hematocrit, 69%). Her colloid osmotic pressure was 4.6mmHg. Following a bolus dose of prednisolone (500mg), fluid resuscitation was initiated. During volume loading, anasarca and acute respiratory distress rapidly developed. Echocardiography revealed an underfilled, hypokinetic, diastolic dysfunctional left ventricle with pericardial effusion but no signs of tamponade. Despite continued fluid resuscitation and high-dosed catecholamine therapy, the patient died from refractory shock 12 hours after intensive care unit admission. A laboratory analysis of her complement system suggested the presence of C1 inhibitor deficiency as the cause for systemic capillary leakage. The post-mortem examination revealed bilateral pleural, pericardial and peritoneal effusions as well as left ventricular hypertrophy with patchy myocardial fibrosis. Different patterns of endomysial/perimysial lymphocytic infiltrations adjacent to degenerated cardiomyocytes in her myocardium and necrotic muscle fibers in her right psoas major muscle were found in the histological examination. Conclusions This case report indicates that acute exacerbation of chronic dermatomyositis can result in a fulminant systemic capillary leak syndrome with intense hemoconcentration, hypovolemic shock and acute heart failure. In the presented patient, the cause for diffuse capillary leakage was most probably acquired angioedema, a condition that has been associated with both lymphoproliferative and autoimmunologic disorders. PMID:24467750

2014-01-01

245

Superior vena cava syndrome due to a leiomyosarcoma of the anterior mediastinum: A case report and literature overview  

PubMed Central

INTRODUCTION Leiomyosarcomas are an infrequent cause of malignant superior vena cava syndrome (VCS). PRESENTATION OF CASE A 51-year old male patient was admitted for a three-day history of dyspnoea, dysphagia and erythema of the head and neck. Computed tomography and magnetic resonance imaging showed a lesion arising on the anterior mediastinum, which was in close proximity with a thrombus in the superior vena cava. Surgical excision was performed, including open resection of the primary tumour and an atrio-innominate vein bypass with 8-mm polytetrafluoroethylene (PTFE). Histology confirmed a leiomyosarcoma and postoperative radiotherapy sessions were performed. Due to evidence of enlargement of the thrombus, a second intervention was undertaken. In this procedure, a remainder of the primary tumour was resected and the superior vena cava reconstructed with an autologous pericardium patch. The patient recovered satisfactorily and was discharged on the seventh postoperative day, with no evidence for relapse after 10 months of follow-up. DISCUSSION Leiomyosarcomas comprise less than 2% of the tumours of the mediastinum and are a rare cause of paraneoplastic VCS. Male patients in their sixties are most commonly affected. Relapses seem to be common, and thus a careful follow-up is often recommended. CONCLUSION In spite of the limited data on the management of thoracic leiomyosarcomas, surgery is currently considered the mainstay of treatment. PMID:25460453

Labarca, E.; Zapico, A.; Ríos, B.; Martinez, F.; Santamarina, M.

2014-01-01

246

Recurrent adult jejuno-jejunal intussusception due to inflammatory fibroid polyp – Vanek’s tumour: a case report  

PubMed Central

Background Adult intussusception is a rare but challenging condition. Preoperative diagnosis is frequently missed or delayed because of nonspecific or sub-acute symptoms. Case presentation We present the case of a sixty-two year old gentleman who initially presented with pseudo-obstruction. Computerised tomography displayed a jejuno-jejunal intussusception, which was treated by primary laparoscopic reduction. The patient re-presented with acute small bowel obstruction two weeks later. He underwent a laparotomy showing recurrent intussusception and required a small bowel resection with primary anastomosis. Histological examination of the specimen revealed that the intussusception lead point was due to an inflammatory fibroid polyp (Vanek’s tumour) causing double invagination. Conclusions Adult intussusception presents with a variety of acute, intermittent, and chronic symptoms, thus making its preoperative diagnosis difficult. Although computed tomography is useful in confirming an anatomical abnormality, final diagnosis requires histopathological analysis. Vanek’s tumours arising within the small bowel rarely present with obstruction or intussusception. The optimal surgical management of adult small bowel intussusception varies between reduction and resection. Reduction can be attempted in small bowel intussusceptions provided that the segment involved is viable and malignancy is not suspected. Virtual Slides The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/7292185123639943 PMID:24968941

2014-01-01

247

Scrotal Swelling and Testicular Atrophy due to Schistosomiasis in a 9-Year-Old Boy: A Case Report  

PubMed Central

Schistosomiasis is a communicable disease which commonly involves urinary bladder causing hematuria, or large bowel causing bloody stool. The common species encountered in this lake region surrounding Lake Victoria in Tanzania are Schistosoma haematobium and Schistosoma mansoni. Complications can lead to portal hypertension due portal fibrosis in liver, and fibrosis in lung can lead to pulmonary hypertension; this commonly seen with S. mansoni. Major complications of S. maeametobium are chronic cystitis with squamous metaplasia with subsequent development of squamous cell carcinoma. Involvement of spinal cord causing paraplegia has been observed in S. haematobium. Other unusual pathology of schistosomiasis has been described, such as involvement of the appendix, ovary, prostate, and cervix. Here, we present a case of schistosomiasis in a 9-year-old boy who presented with left scrotal pain for one year which was accompanied by scrotal swelling; surgical exploration was done, and the finding was hydrocele and atrophic testes with nodules on the surface. Histological examination reveals atrophic testis and heavy active granulomatous inflammation with schistosoma eggs consistent with Schistosoma haematobium in the tunica vaginalis. PMID:22567478

Rambau, Peter F.; Chandika, Alphonce; Chalya, Philipo L.; Jackson, Kahima

2011-01-01

248

Pediatric and Perinatal Pathology: SY21-4 GRANULOMATOUS PNEUMONITIS DUE TO PERFORIN DEFECT - A CASE REPORT.  

PubMed

A 6-year-old girl presented with dry cough and fatigue for 3 weeks, not associated with fever, elevation in inflammatory markers or evidence of a systemic disease. Chest X-rays showed consolidation of the lower lobes and fine reticular opacities in the upper lobes. Lung function was decreased and high inspiratory O2 concentration was required. Lung biopsy showed extensive focal lymphoid infiltration with many granulomas, often small and loose. Necrosis and vasculitis were absent, and infective organisms were not found. An obvious immune defect was not identified. Due to a history of exposure to tea tree spray, hypersensitivity pneumonitis was suggested. Marked improvement followed steroids, but on reduction there was recurrence. Repeat biopsy showed considerably increase in the inflammatory infiltration. Familial lymphohistiocytosis (FLH) was considered even though clinical and laboratory features of haemophagocytic lymphohistiocytosis were absent. Immunofluorescence showed marked reduction in the intracellular perforin expression in the NK cells. K285del/A91?V mutation was found in the PERF1 gene. A bone marrow transplant was performed. The possibility of FLH should be considered in older children and adults when an obvious cause of granulomatous lesion in the lungs and other organs cannot be identified. Bone marrow transplant can sometimes be curative. PMID:25188145

Chow, C W

2014-10-01

249

Correct diagnosis and successful treatment for pericardial effusion due to toothpick injury: A case report and literature review  

PubMed Central

We reported a 55-year-old man who suffered from chest pain and dyspnea on exertion for two weeks associated with night sweating, general malaise, poor appetite, and body weight loss. Physical examination revealed friction rub with distant heart sound, bilateral clear breathing sound, no abdomen tenderness, and normal bowel sound. Subsequent chest X-ray revealed cardiomegaly and cardiac echo showed massive pericardial and pleural effusion with normal left ventricular function. Constrictive pericarditis was diagnosed based on clinical information. Tuberculosis (TB), malignancy, autoimmune disease, infection, hypothyroidism, and idiopathic could be the causes but excluded by further study. High-resolution lung CT scan after reconstruction revealed a moderate amount pericardial effusion with possible superimposed infection. Thickness of pericardium and left lobe liver abscess were found. A straight tubular structure about 6 cm in length transverses the lateral segment of liver to pericardial space and unknown foreign body was suspected. Laparotomy was performed, 6.5 cm toothpick was found through the liver into pericardium. Post-operative course was uneventful and he discharged one week later. The patient could not remember swallowing the toothpick before. He had no chest pain and dyspnea on exertion during a 6-mo follow-up period. PMID:17696263

Liu, Yu-Yin; Tseng, Jeng-Hwei; Yeh, Chun-Nan; Fang, Ji-Tseng; Lee, Hsiang-Lin; Jan, Yi-Yin

2007-01-01

250

Factors affecting successful outcome from ICSI in men following previous vasectomy  

Microsoft Academic Search

There are conflicting reports as to whether the interval between vasectomy and surgical sperm retrieval (SSR) for intra-cytoplasmic\\u000a sperm injection (ISCI) is related to clinical pregnancy (CPR), and live birth (LBR), rates. This study aimed to evaluate factors\\u000a that may influence the outcome of ICSI in males with secondary azoospermia due to previous vasectomy. We analysed the medical\\u000a records of

Stephen J. Bromage; Jamie Douglas; Debbie A. Falconer; Brian A. Lieberman; Stephen R. Payne

2007-01-01

251

Your Dues  

NASA Astrophysics Data System (ADS)

Your AGU dues, at $20, are truly a bargain and have been so for 40 years. It would be difficult to point to the primary driver for the extraordinary growth in AGU membership during the past 40 years, but surely the low and stable dues have been a major contributor. The low entry fee brings a diverse, worldwide community of scientists into our network. It is also consistent with AGU's commitment to the public good, which is the basis for the tax-exempt status the Union enjoys in the United States.

Spilhaus, Fred

2009-01-01

252

Case report of a neonate with ocular toxoplasmosis due to congenital infection: estimation of the percentage of ocular toxoplasmosis in Greece caused by congenital or acquired infection  

PubMed Central

We report a case of a newborn male child with congenital toxoplasmosis. During pregnancy seroconversion occurred and positive titers of antitoxoplasmic antibodies (immunoglobulin M and G) were found in the mother, in the third trimester. She received treatment with spiramycin. After birth, the neonate presented with chorioretinitis and intracranial calcifications. The neonate received treatment with pyrimethamine, sulfadiazine, and leucovorin for 1 year. In addition to using a previously described method, we report for the first time in Greece an estimation regarding the percentage of ocular toxoplasmosis caused by congenital or acquired infection. We estimate that ocular toxoplasmosis in Greece is caused in 7% of the cases by congenital infection, and in 93% of the cases by acquired infection. PMID:24293989

Asproudis, Ioannis; Koumpoulis, Ioannis; Kalogeropoulos, Chris; Sotiropoulos, Georgios; Papassava, Margarita; Aspiotis, Miltiadis

2013-01-01

253

Case report of a neonate with ocular toxoplasmosis due to congenital infection: estimation of the percentage of ocular toxoplasmosis in Greece caused by congenital or acquired infection.  

PubMed

We report a case of a newborn male child with congenital toxoplasmosis. During pregnancy seroconversion occurred and positive titers of antitoxoplasmic antibodies (immunoglobulin M and G) were found in the mother, in the third trimester. She received treatment with spiramycin. After birth, the neonate presented with chorioretinitis and intracranial calcifications. The neonate received treatment with pyrimethamine, sulfadiazine, and leucovorin for 1 year. In addition to using a previously described method, we report for the first time in Greece an estimation regarding the percentage of ocular toxoplasmosis caused by congenital or acquired infection. We estimate that ocular toxoplasmosis in Greece is caused in 7% of the cases by congenital infection, and in 93% of the cases by acquired infection. PMID:24293989

Asproudis, Ioannis; Koumpoulis, Ioannis; Kalogeropoulos, Chris; Sotiropoulos, Georgios; Papassava, Margarita; Aspiotis, Miltiadis

2013-01-01

254

Carnegie Mellon University 1 Previous Catalogs  

E-print Network

Carnegie Mellon University 1 Previous Catalogs · 2013-2014 Catalog (Web, PDF) · 2012-2013 Catalog (Web (http://coursecatalog.web.cmu.edu/ previous/2012-2013), PDF (http://coursecatalog.web.cmu.edu/ previous/1213_catalog.pdf)) · 2011-2012 Catalog (Web (http://coursecatalog.web.cmu.edu/ previous/2011

255

[Recurrent bilateral anterior uveitis due to Leishmania infantum in a patient with immune deficiency related to HIV infection: a case report and literature review].  

PubMed

We report the case of a 56-year-old patient, presenting with bilateral hypertensive anterior uveitis due to Leishmania infantum, in the setting of immune deficiency related to HIV infection. The etiology of the uveitis was diagnosed following detection of L. infantum DNA on anterior chamber paracentesis. Initially, the patient received an intravitreal injection of liposomal amphotericin B, systemic antiparasitic treatment, topical steroid and ocular hypotensive treatment. Due to unfavourable disease progression in the right eye, we re-evaluated the anti-inflammatory, antiretroviral and antiparasitic medications (beginning meglumine antimoniate): the uveitis in the left eye was thus able to be controlled. We followed the efficacy of treatment with weekly quantification of Leishmania DNA in the aqueous humor. Uveitis secondary to leishmaniasis is rare and serious. Physicians must be aware of this cause of uveitis, particularly in immunodeficient patients. The quantitation of Leishmania DNA in the aqueous humor is an indispensible tool for monitoring the disease. PMID:25087128

Perrin-Terrin, A; Auriol, S; Mahieu, L; Debard, A; Eden, A; Cassagne, M; Pagot-Mathis, V; Malecaze, F; Soler, V

2014-09-01

256

Triple outlet right ventricle: a previously unknown cardiac malformation.  

PubMed

We present the case of an infant with three distinct outflow tracts from the right ventricle. Three outlets from the heart have been previously named the "Tritruncal Heart". We review the two previously reported cases of tritruncal hearts and describe the anatomy, diagnosis, surgical management, and outcome of our case. Embryologic implications are also discussed. PMID:24775072

Tingo, Jennifer E; Carroll, Sheila J; Crystal, Matthew A

2015-03-01

257

Specific GC-MS/MS stable-isotope dilution methodology for free 9- and 10-nitro-oleic acid in human plasma challenges previous LC-MS/MS reports.  

PubMed

Nitrated unsaturated fatty acids including nitro-oleic acid (NO(2)-OA) have been measured in human blood samples in their free and esterified forms. Plasma concentrations in healthy subjects have been reported to be of the order of 600 nM for free NO(2)-OA and 300 nM for esterified NO(2)-OA, as measured by LC-MS/MS. In the present article we report a GC-MS/MS method for the specific and accurate quantification of two NO(2)-OA isomers, i.e., 9-NO(2)-OA and 10-NO(2)-OA, in human plasma using newly prepared, isolated, characterized and standardized (15)N-labeled analogs. This method involves SPE extraction of fatty acids from slightly acidified plasma samples (pH 5), conversion to their pentafluorobenzyl (PFB) esters, isolation by HPLC, solvent extraction from a single HPLC fraction and GC-MS/MS analysis in the electron capture negative-ion chemical ionization (ECNICI) mode. Quantification was performed by selected-reaction monitoring (SRM) of m/z 46 ([NO(2)](-)) and m/z 47 ([(15)NO(2)](-)) produced by collision-induced dissociation (CID) from the parent ions [M-PFB](-) at m/z 326 for endogenous 9-NO(2)-OA and 10-NO(2)-OA and m/z 327 for the internal standards 9-(15)NO(2)-OA and 10-(15)NO(2)-OA. We partially validated the GC-MS/MS method for 9-NO(2)-OA and 10-NO(2)-OA in human plasma and quantified these nitro-oleic species in plasma of 15 healthy volunteers. We identified two isomers, i.e., 9-NO(2)-OA and 10-NO(2)-OA, in human plasma under physiological conditions and found these nitrated fatty acids at a mean concentration of 1 nM each. This concentration is about 600 times lower than that reported by others using LC-MS/MS. Our GC-MS/MS studies on nitro-oleic acid and 3-nitrotyrosine suggest that the extent of nitration of biomolecules such as unsaturated fatty acids and tyrosine is very low in health. In this article we discuss analytical and biological ramifications potentially associated with measurement of nitrated biomolecules in biological systems. PMID:19162569

Tsikas, Dimitrios; Zoerner, Alexander; Mitschke, Anja; Homsi, Yahya; Gutzki, Frank-Mathias; Jordan, Jens

2009-09-15

258

Failure of Urological Implants in Spinal Cord Injury Patients due to Infection, Malfunction, and Implants Becoming Obsolete due to Medical Progress and Age-Related Changes in Human Body Making Implant Futile: Report of Three Cases  

PubMed Central

Any new clinical data, whether positive or negative, generated about a medical device should be published because health professionals should know which devices do not work, as well as those which do. We report three spinal cord injury patients in whom urological implants failed to work. In the first, paraplegic, patient, a sacral anterior root stimulator failed to produce erection, and a drug delivery system for intracavernosal administration of vasoactive drugs was therefore implanted; however, this implant never functioned (and, furthermore, such penile drug delivery systems to produce erection had effectively become obsolete following the advent of phosphodiesterase type 5 inhibitors). Subsequently, the sacral anterior root stimulator developed a malfunction and the patient therefore learned to perform self-catheterisation. In the second patient, also paraplegic, an artificial urinary sphincter was implanted but the patient developed a postoperative sacral pressure sore. Eight months later, a suprapubic cystostomy was performed as urethral catheterisation was very difficult. The pressure sore had not healed completely even after five years. In the third case, a sacral anterior root stimulator was implanted in a tetraplegic patient in whom, after five years, a penile sheath could not be fitted because of penile retraction. This patient was therefore established on urethral catheter drainage. Later, infection with Staphylococcus aureus around the receiver block necessitated its removal. In conclusion, spinal cord injury patients are at risk of developing pressure sores, wound infections, malfunction of implants, and the inability to use implants because of age-related changes, as well as running the risk of their implants becoming obsolete due to advances in medicine. Some surgical procedures such as dorsal rhizotomy are irreversible. Alternative treatments such as intermittent catheterisations may be less damaging than bladder stimulator in the long term. PMID:23864980

Vaidyanathan, Subramanian; Soni, Bakul; Singh, Gurpreet; Hughes, Peter; Selmi, Fahed

2013-01-01

259

Expanded Prader-Willi syndrome due to chromosome 15q11.2-14 deletion: report and a review of literature.  

PubMed

We report on a male infant with de novo unbalanced t(5;15) translocation resulting in a 17.23?Mb deletion within 15q11.2-q14 and a 25.12?kb deletion in 5pter. The 15q11.2-q14 deletion encompassed the 15q11.2-q13 Prader-Willi syndrome (PWS) critical region and the recently described 15q13.3 microdeletion syndrome region while the 5pter deletion contained no RefSeq genes. From our literature review, patients with similar deletions in chromosome 15q exhibit expanded phenotype of severe developmental delay, protracted feeding problem, absent speech, central visual impairment, congenital malformations and epilepsy in addition to those typical of PWS. The patient reported herein had previously unreported anomalies of mega cisterna magna, horseshoe kidney and the rare neonatal interstitial lung disease known as pulmonary interstitial glycogenosis. Precise breakpoint delineation by microarray is useful in patients with atypical PWS deletions to guide investigation and prognostication. PMID:23633107

Liu, Anthony P Y; Tang, Wing Fai; Lau, Elizabeth T; Chan, Kelvin Y K; Kan, Anita S Y; Wong, Kar Yin; Tso, Winnie W Y; Jalal, Khair; Lee, So Lun; Chau, Christy S K; Chung, Brian H Y

2013-06-01

260

Pancoast's Syndrome due to Fungal Abscess in the Apex of Lung in an Immunocompetent Individual: A Case Report and Review of the Literature  

PubMed Central

Malignant tumours in the apices of the lungs, especially bronchogenic carcinoma (Pancoast tumours), are the most common cause of Pancoast' syndrome which presents with shoulder or arm pain radiating along the medial aspect of forearm and weakness of small muscles of hand with wasting of hypothenar eminence due to neoplastic involvement of C8 and T1 and T2 nerve roots of brachial plexus. There are a number of benign conditions which may lead to Pancoast's syndrome; fungal abscess located in the apex of lung is one of them. Oral or intravenous antifungals are the treatment of choice in this case and complete recovery is usual, whereas, surgical resection followed by chemoradiotherapy is the treatment of choice in case of Pancoast's syndrome due to lung cancers. Hence, tissue diagnosis is mandatory. Here, we report a case of apical fungal abscess causing Pancoast's syndrome in an immunocompetent individual of 35 years of age to raise the awareness among the clinicians regarding this rare clinical entity. PMID:25302130

Das, Anirban; Choudhury, Sabyasachi; Basuthakur, Sumitra; Das, Sibes Kumar; Mukhopadhyay, Angshuman

2014-01-01

261

INTRODUCTION We have reported in previous studies that  

E-print Network

involvement. Here we investigate brain areas underlying acute thermal pain in chronic back pain patients (CBP Differences Between Back Pain Patients And Healthy Subjects For Acute Thermal Pain M.N. Baliki1,D.R. ChialvoPFC BOLD response appears to be specific for spontaneous back pain since it shows a significant increase

Apkarian, A. Vania

262

Progressive dysphagia and neck pain due to diffuse idiopathic skeletal hyperostosis of the cervical spine: a case report and literature review  

PubMed Central

Diffuse idiopathic skeletal hyperostosis (DISH) is considered an underdiagnosed and mostly asymptomatic nonprimary osteoarthritis. The etiology of DISH remains unknown and the validated diagnostic criteria are absent. This condition is still recognized radiologically only. Rarely, large projecting anterior osteophytes result in esophageal impingement and distortion leading to dysphagia. We report the case of progressive dysphagia and neck pain due to DISH of the cervical spine in a 70-year-old man, which was surgically removed with excellent postoperative results and complete resolution of symptoms. Imaging studies, surgical findings, and histopathological examinations were used to support the diagnosis. The patient was successfully treated with total excision of the anterior osteophytes with no evidence of recurrence 12 months after surgery. In this report, we also discuss the clinical features and perioperative considerations in combination with a literature review. Our patient illustrates that clinicians should be aware of this rare clinical manifestation as the presenting feature of DISH in cervical spine. Surgical decompression through osteophytectomy is effective for patients who fail conservative treatment. PMID:24729695

Zhang, Chao; Ruan, Dike; He, Qing; Wen, Tianyong; Yang, Pushan

2014-01-01

263

X-linked severe combined immunodeficiency due to a novel mutation complicated with hemophagocytic lymphohistiocytosis and presented with invagination: A case report.  

PubMed

Severe combined immunodeficiency (SCID) is an inherited disease with profoundly defective T cells, B cells, and natural killer (NK) cells. X-linked SCID (X-SCID) is its most common form. In this report, we describe a 4-month-old male with X-SCID who presented invagination and also showed hemophagocytic lymphohistiocytosis (HLH). The patient was admitted to our hospital with fever, cough, vomiting, monoliasis, and hepatosplenomegaly in postoperative period at the age of 3 months. The laboratory finding revealed no detectable T cells and hypogammaglobulinemia despite normal B-cell counts. Diagnosis of X-SCID was established by DNA analysis of the interleukin (IL)-2 receptor gamma chain gene (IL2RG); namely, we detected the novel mutation in the splice-site of exon 5 (c.595-1G>T). The patient died due to infection at the age of 4 months. Also, this case is the first report that describes the patient with X-SCID with presented invagination. PMID:25215194

Patiroglu, Turkan; Haluk Akar, H; van den Burg, Mirjam; Unal, Ekrem; Akyildiz, Basak N; Tekerek, Nazan U; Yilmaz, Ebru

2014-09-01

264

Incentive Sensitization by Previous Amphetamine Exposure: Increased Cue-Triggered "Wanting" for Sucrose Reward  

E-print Network

Incentive Sensitization by Previous Amphetamine Exposure: Increased Cue-Triggered "Wanting Arbor, Michigan 48109 We reported previously that an amphetamine microinjection into the nucleus- mental pursuit. Here we show that sensitization caused by previous amphetamine administration also causes

Berridge, Kent

265

Aortoesophageal fistula due to esophageal ulcer.  

PubMed

Aortoesophageal fistula is a rare but fatal disease. Many such fistulas are caused by an aortic aneurysm, a previous operation, or esophageal disease. We report a case of aortoesophageal fistula due to an esophageal ulcer. A 66-year-old man suffered massive hematemesis; he was diagnosed as having an aortoesophageal fistula due to an esophageal ulcer after examination by upper endoscopy, computed tomography, and angiography. He had no aortic aneurysm, nor was there a history of a previous operation. An emergency operation was performed, but we could only accomplish closure because clamping of the aorta was impossible, and the source of the bleeding could not be established. He died 4 days later after sudden hemorrhage. Surgical outcome depends on early surgical intervention before massive hemorrhage occurs. PMID:19440823

Takano, Shinji; Katsuhara, Kazuhiro; Nobuhara, Kenji; Ueda, Shigeharu; Imura, Masato; Hohjo, Yoshihisa

2009-05-01

266

An uncommon cause of tardy ulnar nerve palsy due to upper extremity prolonged malposition in a comatose child: a case report  

PubMed Central

Abstract: Background: Ulnar nerve neuropathy is one of the most common peripheral nerve dysfunctions. Elbow is the most common area affected by ulnar nerve which is mainly because of fractures or dislocations of this area. Delayed ulnar nerve palsy (Tardy Ulnar Nerve Palsy) in children due to a malpositioning of upper extremity during hospitalization is an uncommon cause of ulnar nerve injury which we have already reported it. Methods: An eight-year-old conscious patient who had weakness, paresthesia and tingling in the right 4th and 5th fingers, as well as right claw hand deformity was evaluated, he had attended once before in 4 months ago due to head trauma in coma state. The child had no clinical and radiological indications of arm or elbow fractures causing nerve compression or entrapment. Elbow malposition had caused ulnar nerve neuropathy during hospitalization. Surgery was attempted, ulnar nerve decompression and anterior transposition done. Results: After three weeks post operatively, active physical therapy was started on the right upper extremity and the hand returned to normal activity after 6 months. Conclusions: In patients with decreased level of consciousness or coma state who need prolonged hospitalization, the limbs must remain in correct position to prevent superficial nerve injuries and neuropathies. Furthermore, careful and scrutinized attention to the traumatic patients and doing on time and targeted imaging, regular follow up of patients, complete and perfect neurological examinations can prevent peripheral nerve injuries or develop on-time treatments which improve the patients' quality of life. Keywords: Ulnar nerve, Elbow malposition, Ulnar nerve decompression

Emamhadi, Mohammad Reza; Mahmoudi, Davood

2012-01-01

267

Observations on water system and pipeline performance in the Limon area of Costa Rica due to the April 22, 1991 earthquake. Technical report  

SciTech Connect

The document focuses on earthquake damage to water and oil pipelines, water supply, and water treatment following the 22 April 1991 Costa Rica Earthquake. The moment magnitude 7.5 earthquake occurred approximately 40 km south-southwest of Limon, and resulted in a coseismic uplift of up to 1.5 meters along Costa Rica's east coast. The report also provides an overview of the engineering aspects of the event and recovery activities. Turbidity in the watershed which provides Limon's primary water supply increased to as high as 2.4 percent solids, making it extremely difficult to treat. In addition, the water treatment plant was damaged by the earthquake. Cast iron, ductile iron and reinforced concrete cylinder pipe water transmission lines were damaged by both wave propagation and permanent ground deformation. Water distribution piping, also including PVC and galvanized iron, was similarly impacted. Documentation and evaluation of that damage is described, and compared with empirical estimates from previous earthquakes. Twin 150 mm (6 in), 100 km long, oil transmission lines suffered only a single failure from wrinkling. A description of the pipelines and the failure is provided.

O'Rourke, M.J.; Ballantyne, D.

1992-06-30

268

Table 6.2 Change In the Vietnam/Non-Vietnam Odds Ratio Due to Adding Reporte!cI Childhood Behavior Problems and Drug Use In the Army to the Final LC"Jlstlc  

E-print Network

Table 6.2 Change In the Vietnam/Non-Vietnam Odds Ratio Due to Adding Reporte!cI Childhood Behavior a Adjusted odds ratio for Vietnam relative to non-Vietnam. b Covariates include place of service, year

269

Potential hazard due to induced radioactivity secondary to radiotherapy: the report of task group 136 of the American Association of Physicists in Medicine.  

PubMed

External-beam radiation therapy mostly uses high-energy photons (x-rays) produced by medical accelerators, but many facilities now use proton beams, and a few use fast-neutron beams. High-energy photons offer several advantages over lower-energy photons in terms of better dose distributions for deep-seated tumors, lower skin dose, less sensitivity to tissue heterogeneities, etc. However, for beams operating at or above 10 MV, some of the materials in the accelerator room and the radiotherapy patient become radioactive due primarily to photonuclear reactions and neutron capture, exposing therapy staff and patients to unwanted radiation dose. Some recent advances in radiotherapy technology require treatments using a higher number of monitor units and monitor-unit rates for the same delivered dose, and compared to the conventional treatment techniques and fractionation schemes, the activation dose to personnel can be substantially higher. Radiotherapy treatments with proton and neutron beams all result in activated materials in the treatment room. In this report, the authors review critically the published literature on radiation exposures from induced radioactivity in radiotherapy. They conclude that the additional exposure to the patient due to induced radioactivity is negligible compared to the overall radiation exposure as a part of the treatment. The additional exposure to the staff due to induced activity from photon beams is small at an estimated level of about 1 to 2 mSv y. This is well below the allowed occupational exposure limits. Therefore, the potential hazard to staff from induced radioactivity in the use of high-energy x-rays is considered to be low, and no specific actions are considered necessary or mandatory. However, in the spirit of the "As Low as Reasonably Achievable (ALARA)" program, some reasonable steps are recommended that can be taken to reduce this small exposure to an even lower level. The dose reduction strategies suggested should be followed only if these actions are considered reasonable and practical in the individual clinics. Therapists working with proton beam and neutron beam units handle treatment devices that do become radioactive, and they should wear extremity monitors and make handling apertures and boluses their last task upon entering the room following treatment. Personnel doses from neutron-beam units can approach regulatory limits depending on the number of patients and beams, and strategies to reduce doses should be followed. PMID:25271934

Thomadsen, Bruce; Nath, Ravinder; Bateman, Fred B; Farr, Jonathan; Glisson, Cal; Islam, Mohammad K; LaFrance, Terry; Moore, Mary E; George Xu, X; Yudelev, Mark

2014-11-01

270

Babesiosis due to the canine Babesia microti-like small piroplasm in dogs - first report from Portugal and possible vertical transmission  

PubMed Central

Background Canine babesiosis (or piroplasmosis) is endemic in northern Portugal, but molecularly confirmed cases of infection with small piroplasms have not been reported in the country. Three German shepherd dogs - a bitch and its 2-month old pup and an unrelated male - clinically suspected of piroplasmosis were assessed for babesial infection. Results Parasitemia with small piroplasms was detected by microscopy in two dogs. All three dogs were positive by PCR and the Babesia microti-like small piroplasm (syn. Theileria annae) was identified by DNA sequencing. These are the first confirmed cases of babesiosis caused by the B. microti-like piroplasm both in dogs from Portugal and in dogs suspected of clinical piroplasmosis outside of Spain. Conclusions Although the bitch and the male had visited neighboring Galicia (northwestern Spain), where the disease is endemic, incursion of this piroplasm into northern Portugal is evident and infection of the non-traveled pup was due to either vertical transmission or autochthonous tick infection. PMID:21489238

2011-01-01

271

Ecthyma gangrenosum skin lesions in previously healthy children.  

PubMed

Ecthyma gangrenosum (EG) is an uncommon skin lesion that usually develops in patients with known immune deficiency or who are on immunosuppressive treatment. We report on five previously healthy children presenting with EG. Three of them developed severe neutropenia. Immunologic workup revealed chronic neutropenia in two. PMID:25469722

Cohen, Neta; Capua, Tali; Bilavsky, Efraim; Dias-Polak, Hila; Levin, Dror; Grisaru-Soen, Galia

2014-12-01

272

Inhibitors in previously treated patients: A review of the literature  

PubMed Central

Previously treated patients are the first patients to receive novel factor VIII products during clinical investigations under the rationale that a product with increased antigenicity is more likely to be detected in this population because of a low baseline risk of inhibitor formation compared to previously untreated patients. Since clinical investigations of factor products are not typically randomized comparisons, the rate of new inhibitor formation in a clinical trial is compared with the expected rates based on prior reports. The published experience of inhibitors in previously treated patients informs the number of new inhibitors per cohort that are acceptable in a clinical trial. However a single acceptable limit of new inhibitors fails to recognize the heterogeneity of inhibitors and their variable impact on clinical care. This review will discuss the published literature on epidemiology and clinical characteristics of inhibitors and possible risk factors for formation in previously treated patients. PMID:20536987

Kempton, Christine L.

2014-01-01

273

Association between primary hyperparathyroidism and previous irradiation  

SciTech Connect

The association between primary hyperparathyroidism and previous irradiation was investigated in two study groups. Among 36 patients with hyperparathyroidism, 4 (11%) knew of having received radiation therapy. In the second group of 323 patients with a history of radiation exposure and nodular thyroid disease, 4 (1%), thus far, were found to have hyperparathyroidism.

Tamura, K.; Shimaoka, K.; Spaulding, S.; Shedd, D.

1982-04-01

274

Anaphylaxis due to caffeine  

PubMed Central

We report a rare case of anaphylaxis due to caffeine intake. A 27-year-old woman suffered her first episode of anaphylaxis and a positive skin prick test suggested that the anaphylaxis was due to an IgE-mediated hypersensitivity reaction to caffeine. She was diagnosed with caffeine allergy and has not had an allergic reaction after avoiding foods and drinks containing caffeine. Although caffeine is known to have antiallergic effects, this case shows that caffeine can be an allergen and cause anaphylaxis. PMID:25653922

Cho, Tatsurai; Tatewaki, Masamitsu; Onishi, Shogo; Yokoyama, Tatsuya; Yoshida, Naruo; Fujimatsu, Takayoshi; Hirata, Hirokuni; Fukuda, Takeshi; Fukushima, Yasutsugu

2015-01-01

275

A previously undescribed coronavirus associated with respiratory disease in humans  

Microsoft Academic Search

The etiology of acute respiratory tract illnesses is sometimes unclear due to limitations of diagnostic tests or the existence of as-yet-unidentified pathogens. Here we describe the identification and characterization of a not previously recognized coronavirus obtained from an 8-mo-old boy suffering from pneumonia. This coronavirus replicated efficiently in tertiary monkey kidney cells and Vero cells, in contrast to human coronaviruses

R. A. M. Fouchier; N. G. Hartwig; T. M. Bestebroer; B. Niemeyer; J. H. Simon; A. D. M. E. Osterhaus; Jong de J. C

2004-01-01

276

Clinical and radiological deterioration due to Mycobacterium szulgai in an asthmatic patient.  

PubMed

We report the case of a 23-year-old asthmatic woman who had clinical and radiological deterioration due to Mycobacterium szulgai infection and good response to anti-mycobacterial treatment without any structural abnormalities in previous lung imaging studies. M. szulgai may be considered a pathogen able to cause deterioration of respiratory health even in patients with previously normal lungs. PMID:22240435

Marjani, Majid; Mansouri, Nahal; Tabarsi, Payam; Baghaei, Parvaneh; Farnia, Parissa; Sheikholslami, Fatemeh-Maryam; Mansouri, Davood

2012-01-01

277

Placenta previa and previous cesarean section  

Microsoft Academic Search

Objective: To assess the relationship between previous cesarean section and subsequent development of placenta previa and placenta previa with accreta. Method: The records of all patients delivered with the diagnosis of placenta previa during the 10-year period from 1984 to 1993 were reviewed. Results: From a total of 50 485 deliveries, 421 (0.83%) had placenta previa, 43 (10.2%) of whom

W. W. K. To; W. C. Leung

1995-01-01

278

Previous Open Rotor Research in the US  

NASA Technical Reports Server (NTRS)

Previous Open Rotor noise experience in the United States, current Open Rotor noise research in the United States and current NASA prediction methods activities were presented at a European Union (EU) X-Noise seminar. The invited attendees from EU industries, research establishments and universities discussed prospects for reducing Open Rotor noise and reviewed all technology programs, past and present, dedicated to Open Rotor engine concepts. This workshop was particularly timely because the Committee on Aviation Environmental Protection (CAEP) plans to involve Independent Experts in late 2011 in assessing the noise of future low-carbon technologies including the open rotor.

VanZante, Dale

2011-01-01

279

Current Psychopathology in Previously Assaulted Older Adults  

ERIC Educational Resources Information Center

Older adult women age 55+ years (N = 549) were interviewed as part of a population-based epidemiological research study of lifetime experiences with physical and sexual assault and current mental health problems. Although overall rates of psychopathology were low, producing very small cells for comparison, women who reported experiencing physical…

Acierno, Ron; Lawyer, Steven R.; Rheingold, Alyssa; Kilpatrick, Dean G.; Resnick, Heidi S.; Saunders, Benjamin E.

2007-01-01

280

Marked hydronephrosis and hydroureter after distigmine therapy in an adult male patient with paraplegia due to spinal cord injury: a case report  

PubMed Central

Introduction Distigmine, a long-acting anti-cholinesterase, is associated with side effects such as Parkinsonism, cholinergic crisis, and rhabdomyolysis. We report a spinal cord injury patient, who developed marked hydronephrosis and hydroureter after distigmine therapy, which led to a series of complications over subsequent years. Case presentation A 38-year-old male developed T-9 paraplegia in 1989. Intravenous urography, performed in 1989, showed normal kidneys, ureters and bladder. He was prescribed distigmine bromide orally and was allowed to pass urine spontaneously. In 1992, intravenous urography showed bilateral marked hydronephrosis and hydroureter. Distigmine was discontinued. He continued to pass urine spontaneously. In 2006, intravenous urography showed moderate dilatation of both pelvicalyceal systems and ureters down to the level of urinary bladder. This patient was performing self-catheterisation only once a day. He was advised to do catheterisations at least three times a day. In December 2008, this patient developed haematuriawhich lasted for nearly four months.. He received trimethoprim, then cephalexin, followed by Macrodantin, amoxicillin and ciprofloxacin. In February 2009, intravenous urography showed calculus at the lower pole of left kidney. Both kidneys were moderately hydronephrotic. Ureters were dilated down to the bladder. Dilute contrast was seen in the bladder due to residual urine. This patient was advised to perform six catheterisations a day, and take propiverine hydrochloride 15 mg, three times a day. Microbiology of urine showed Klebsiella oxytoca, Pseudomonas aeruginosa, and Enterococcus faecalis. Cystoscopy revealed papillary lesions in bladder neck and trigone. Transurethral resection was performed. Histology showed marked chronic cystitis including follicular cystitis and papillary/polypoid cystitis. There was no evidence of malignancy. Conclusion Distigmine therapy resulted in marked bilateral hydronephrosis and hydroureter. Persistence of hydronephrosis after omitting distigmine, and presence of residual urine in bladder over many years probably predisposed to formation of polypoid cystitis and follicular cystitis, and contributed to prolonged haematuria, which occurred after an episode of urine infection. This case illustrates the dangers of prescribing distigmine to promote spontaneous voiding in spinal cord injury patients. Instead of using distigmine, spinal cord injury patients should be advised to consider intermittent catheterisation together with oxybutynin or propiverine to achieve complete, low-pressure emptying of urinary bladder. PMID:19918519

Mansour, Paul; Soni, Bakul M; Hughes, Peter L; Singh, Gurpreet; Oo, Tun

2009-01-01

281

Congruency sequence effects are driven by previous-trial congruency, not previous-trial response conflict  

PubMed Central

Congruency effects in distracter interference tasks are often smaller after incongruent trials than after congruent trials. However, the sources of such congruency sequence effects (CSEs) are controversial. The conflict monitoring model of cognitive control links CSEs to the detection and resolution of response conflict. In contrast, competing theories attribute CSEs to attentional or affective processes that vary with previous-trial congruency (incongruent vs. congruent). The present study sought to distinguish between conflict monitoring and congruency-based accounts of CSEs. To this end, we determined whether CSEs are driven by previous-trial reaction time (RT)—a putative measure of response conflict—or by previous-trial congruency. In two experiments using a face-word Stroop task (n = 49), we found that current-trial congruency effects did not vary with previous-trial RT independent of previous-trial congruency. In contrast, current-trial congruency effects were influenced by previous-trial congruency independent of previous-trial RT. These findings appear more consistent with theories that attribute CSEs to non-conflict processes whose recruitment varies with previous-trial congruency than with theories that link CSEs to previous-trial response conflict. PMID:24027550

Weissman, Daniel H.; Carp, Joshua

2013-01-01

282

Obinutuzumab for previously untreated chronic lymphocytic leukemia.  

PubMed

Obinutuzumab was approved by the Food and Drug Administration in late 2013 for use in combination with chlorambucil for the treatment of patients with previously untreated chronic lymphocytic leukemia (CLL). The approval was based on results of an open-label phase 3 trial that showed improved progression-free survival (PFS) with the combination of obinutuzumab plus chlorambucil compared with chlorambucil alone. Obinutuzumab is a monoclonal antibody that targets CD20 antigen expressed on the surface of pre B- and mature B-lymphocytes. After binding to CD20, obinutuzumab mediates B-cell lysis by engaging immune effector cells, directly activating intracellular death signaling pathways, and activating the complement cascade. Immune effector cell activities include antibody-dependent cellular cytotoxicity and antibody-dependent cellular phagocytosis. PMID:24971420

Abraham, Jame; Stegner, Mark

2014-04-01

283

Books average previous decade of economic misery.  

PubMed

For the 20(th) century since the Depression, we find a strong correlation between a 'literary misery index' derived from English language books and a moving average of the previous decade of the annual U.S. economic misery index, which is the sum of inflation and unemployment rates. We find a peak in the goodness of fit at 11 years for the moving average. The fit between the two misery indices holds when using different techniques to measure the literary misery index, and this fit is significantly better than other possible correlations with different emotion indices. To check the robustness of the results, we also analysed books written in German language and obtained very similar correlations with the German economic misery index. The results suggest that millions of books published every year average the authors' shared economic experiences over the past decade. PMID:24416159

Bentley, R Alexander; Acerbi, Alberto; Ormerod, Paul; Lampos, Vasileios

2014-01-01

284

[Adhesion ileus in patient with previous diagnosis of Ogilvie's syndrome].  

PubMed

A case of a 72-year-old man with abdominal pain and ileus is reported. Previous surgery for Ogilvie's syndrome had been performed. Despite conservative therapy, the occlusive symptoms worsen. Therefore the patient was submitted to surgery. At laparotomy two abdominal adhesions were found and sectioned. The differential diagnosis between mechanical ileus and pseudoobstruction for neuro-mechanics dissociation (Ogilvie's syndrome) is difficult, particularly in patients with neurodegenerative diseases. PMID:16329775

Mongardini, M; Schillaci, F; Cola, A; Fanello, G; Benedetti, F; Maturo, A; Pappalardo, G

2005-01-01

285

Pregnancy hemoperitoneum and placenta percreta in a patient with previous pelvic irradiation and ovarian failure  

SciTech Connect

Placenta percreta in a patient with previous pelvic irradiation has never been described. Reported is a case of placenta percreta with hemoperitoneum associated with a second-trimester incomplete abortion in a patient with previous pelvic irradiation and ovarian failure.

Pridjian, G.; Rich, N.E.; Montag, A.G. (Univ. of Chicago, IL (USA))

1990-05-01

286

Successful recycling of a previously transplanted heart: another option for limited resources.  

PubMed

We report a case of successful reuse of a previously transplanted heart. The organ was retransplanted 16 days after the initial transplantation into a 60-year-old man who had previously received a left ventricular assist device. PMID:25442443

Mullen, John C; Kuurstra, Emily J; Burhani, Mohamad S; Ganta, Srujan; Lalonde, Lucille

2014-11-01

287

5 CFR 732.301 - Due process.  

Code of Federal Regulations, 2010 CFR

...2010-01-01 false Due process. 732.301 Section 732...Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE...NATIONAL SECURITY POSITIONS Due Process and Reporting § 732.301 Due process. When an...

2010-01-01

288

Sebacinales Everywhere: Previously Overlooked Ubiquitous Fungal Endophytes  

PubMed Central

Inconspicuous basidiomycetes from the order Sebacinales are known to be involved in a puzzling variety of mutualistic plant-fungal symbioses (mycorrhizae), which presumably involve transport of mineral nutrients. Recently a few members of this fungal order not fitting this definition and commonly referred to as ‘endophytes’ have raised considerable interest by their ability to enhance plant growth and to increase resistance of their host plants against abiotic stress factors and fungal pathogens. Using DNA-based detection and electron microscopy, we show that Sebacinales are not only extremely versatile in their mycorrhizal associations, but are also almost universally present as symptomless endophytes. They occurred in field specimens of bryophytes, pteridophytes and all families of herbaceous angiosperms we investigated, including liverworts, wheat, maize, and the non-mycorrhizal model plant Arabidopsis thaliana. They were present in all habitats we studied on four continents. We even detected these fungi in herbarium specimens originating from pioneering field trips to North Africa in the 1830s/40s. No geographical or host patterns were detected. Our data suggest that the multitude of mycorrhizal interactions in Sebacinales may have arisen from an ancestral endophytic habit by specialization. Considering their proven beneficial influence on plant growth and their ubiquity, endophytic Sebacinales may be a previously unrecognized universal hidden force in plant ecosystems. PMID:21347229

Weiß, Michael; Sýkorová, Zuzana; Garnica, Sigisfredo; Riess, Kai; Martos, Florent; Krause, Cornelia; Oberwinkler, Franz; Bauer, Robert; Redecker, Dirk

2011-01-01

289

Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature  

PubMed Central

Herein is presented an interesting case of small-cell neuroendocrine carcinoma of the cervix which initially manifests as seizures due to hyponatremia caused by paraneoplastic syndrome of inappropriate anti diuretic hormone (SIADH). Awareness of a paraneoplastic syndrome at presentation can lead to early diagnosis and early initiation of treatment. The management is also unique in that it combines treating the paraneoplastic aspects as well as targeting the tumour itself. Multimodality treatment gives the best outcome in this aggressive tumour. PMID:25114722

Kuriakose, Santhosh; Umadevi, N; Mathew, Sheela; Supriya, NK; Aravindan, KP; Smitha, DS; Amritha Malini, G

2014-01-01

290

Congestive myelopathy (Foix-Alajouanine Syndrome) due to intradural arteriovenous fistula of the filum terminale fed by anterior spinal artery: Case report and review of literature  

PubMed Central

Spinal arteriovenous fistulas are rare entities. They often present with congestive myelopathy but are infrequently diagnosed as the cause of the patients’ symptoms. Only one such case has been described previously in Indian literature. We describe one such case who presented to us after a gap of 3 years since symptom onset and following a failed laminectomy where the cause was later diagnosed to be an intradural fistula in the filum terminale fed by the anterior spinal artery and review the available literature. PMID:24101838

Krishnan, Prasad; Banerjee, Tapas Kumar; Saha, Manash

2013-01-01

291

Nursing Workforce: Emerging Nurse Shortages Due to Multiple Factors. Report to the Chairman, Subcommittee on Health, Committee on Ways and Means, House of Representatives.  

ERIC Educational Resources Information Center

Current evidence suggests emerging shortages of nurses available or willing to fill some vacant positions in hospitals, nursing homes, and home care. Total employment of registered nurses (RNs) per capita and the national unemployment rate for RNs have declined, and providers from around the country report growing difficulty recruiting and…

Heinrich, Janet

292

Contact Urticaria with Systemic Symptoms due to Hexylene Glycol in a Topical Corticosteroid: Case Report and Review of Hypersensitivity to Glycols  

Microsoft Academic Search

We report a case of severe contact urticaria with systemic involvement resembling an anaphylactic reaction, following the application of a topical corticosteroid. This was caused by hexylene glycol, an excipient in the formulation. Glycols are widely used in cosmetics, foods and topical and systemic drugs. In particular, glycols are present in many topical drugs used by dermatologists. To our knowledge,

D. Spoerl; K. Scherer; A. J. Bircher

2010-01-01

293

1979J2 - Discovery of a previously unknown Jovian satellite  

NASA Technical Reports Server (NTRS)

Detailed examination of imaging data of Jupiter taken by Voyager 1 reveals a previously unknown satellite 1979J2. Analysis of the image on the Jovian disk indicates that it is not an atmospheric feature or the shadow of any known satellite. The orbital period is calculated at 16 hours 11 minutes 21.25 seconds + or - 0.5 second and the semimajor axis is 3.1054 Jupiter radii. The observed profile is roughly circular with a diameter of 80 kilometers. An albedo of approximately 0.05 is reported, which is similar to Amalthea's. The geometry of the observational situation is illustrated.

Synnott, S. P.

1980-01-01

294

Hospitalization Due to Co-Morbid Conditions is the Main Cost Driver Among Subjects With COPD-A Report From the Population-Based OLIN COPD Study.  

PubMed

Abstract Background: Co-morbidities are common in COPD; however, there is a lack of population-based studies evaluating the health economic impact of co-morbid diseases for subjects with COPD. The main objective of this study was to estimate annual direct health-care costs, divided into costs due to non-respiratory and respiratory conditions, comparing subjects with and without COPD. Methods: Subjects with and without COPD derived from population-based cohorts in northern Sweden have been invited to annual examinations involving spirometry and structured interviews since 2005. This paper is based on data from 1472 subjects examined in 2006. COPD classification was based on spirometry. Results: Mean annual costs for both respiratory and non-respiratory conditions were significantly higher for subjects with COPD than non-COPD subjects, in total USD 2139 vs. USD 1276 (p = 0.026), and COPD remained significantly associated with higher costs also after adjustment for common confounders as age, smoking habits, BMI and sex. The mean total cost increased with COPD disease severity and was higher for all severity stages (GOLD) than for non-COPD subjects. Hospitalization due to non-respiratory diseases was the main cost driver in COPD, after adjustment for common confounders amounting to about 46% (unadjusted 62%) of the total COPD-costs. Conclusions: Costs were higher for COPD than non-COPD. In COPD, costs for co-morbid conditions were higher than those for respiratory conditions, and hospitalization due to co-morbid conditions was the main cost driver also when adjusted for common confounders. PMID:25415366

Jansson, Sven-Arne; Backman, Helena; Rönmark, Eva; Lundbäck, Bo; Lindberg, Anne

2014-11-21

295

Osteomyelitis due to multiple carbapenemase-producing Gram-negative bacteria: The first case report of a GES-13-producing Pseudomonas aeruginosa isolate in Canada  

PubMed Central

A case of osteomyelitis in an infant following a burn injury sustained in Pakistan caused by a GES-13-producing Pseudomonas aeruginosa (the first reported in Canada) and an OXA-48 producing Klebsiella pneumoniae is described. The present case serves to highlight the importance of international travel as a risk factor for infection with carbapenemase-producing bacteria and the challenges in the laboratory detection of these organisms. PMID:25285131

Sepehri, Shadi; Poliquin, Guillaume; Alfattoh, Nora; Boyd, David; Mulvey, Michael; Denisuik, Andrew; Fanella, Sergio; Karlowsky, James; Walkty, Andrew

2014-01-01

296

Broca’s aphasia due to cerebral venous sinus thrombosis following chemotherapy for small cell lung cancer: A case report and review of literature  

PubMed Central

Cancer is associated with an increased risk of cerebrovascular incidents and treatment with chemotherapy enhances that risk further. Brocha’s aphasia is a stroke-related syndrome, the presentation of which has been rarely reported during cisplatin-based chemotherapy. The current study presents the case of a 27-year-old male with advanced-stage small cell lung cancer. The patient developed Broca’s aphasia following cisplatin-based chemotherapy.

TUNCEL, TOLGA; OZGUN, ALPASLAN; EMIRZEO?LU, LEVENT; CEL?K, SERKAN; DEM?R, SERKAN; BILGI, OGUZ; KARAGOZ, BULENT

2015-01-01

297

An uncommon presentation for a severe invasive infection due to methicillin-resistant Staphylococcus aureus clone USA300 in Italy: a case report  

Microsoft Academic Search

BACKGROUND: Methicillin resistant Staphylococcus aureus (MRSA) has been considered for many years a typical nosocomial pathogen. Recently MRSA has emerged as a frequent cause of infections in the community. More commonly, community-acquired (CA)-MRSA is a cause of infections of the skin and soft-tissues, but life-threatening infections such as necrotizing pneumonia and sepsis can occasionally occur. CASE PRESENTATION: This report describes

Piero Valentini; Gabriella Parisi; Monica Monaco; Francesca Crea; Teresa Spanu; Orazio Ranno; Mirella Tronci; Annalisa Pantosti

2008-01-01

298

Impaired cognitive function due to cerebellar infarction and improvement after stent-assisted angioplasty for intracranial vertebral artery stenosis--case report.  

PubMed

A 69-year-old female presented with multiple cerebellar infarctions and mild cognitive dysfunction. Cerebral angiography revealed severe right vertebral artery (VA) stenosis just proximal to the origin of the posterior inferior cerebellar artery. Neuropsychology tests showed the mini-mental state examination (MMSE) score was 21, and the Wechsler Adult Intelligence Scale-Revised (WAIS-R) score was 70. Cerebrovascular reactivity (CVR) was decreased in the bilateral cerebral and cerebellar hemispheres. Stent-assisted angioplasty of the right VA was performed to prevent recurrence of the cerebellar infarction. Post-procedure, the neuropsychology tests showed cognitive improvement to MMSE score of 26 and WAIS-R score of 84. CVR had also improved in the bilateral cerebral hemispheres. Cerebellar hypoperfusion due to VA stenosis had probably caused functional depression of the cerebello-cerebral pathway, a condition referred to as crossed cerebello-cerebral diaschisis. In this case, cognitive dysfunction was reversed due to recovery of the cerebello-cerebral pathway. PMID:20185879

Ito, Yoshiro; Matsumaru, Yuji; Suzuki, Kensuke; Matsumura, Akira

2010-01-01

299

A previously unreported locality record for the Gila monster (Heloderma suspectum)  

USGS Publications Warehouse

Although the Gila Monster (Heloderma suspectum) is widely distributed throughout the Sonoran and portions of the Mojave Deserts of the southwestern United States and northwestern Mexico, details of its distribution in California are imperfectly known, due to the apparent rarity of the species in that state. In their review of Gila Monster records for California, Lovich and Beaman (2007) documented only 26 credible sightings during a period of 153 years. In May 2009 another sighting in California was documented by Ruppert (2010a, b) who photographed a specimen in the Providence Mountains, an area known for previous Gila Monster sightings (Lovich and Beaman 2007). In this paper we report the 28th credible record of a Gila Monster in California.

Lovich, Jeff; Haxel, Gordon

2011-01-01

300

Upon Further Review: V. An Examination of Previous Lightcurve Analysis from the Palmer Divide Observatory  

Microsoft Academic Search

Updated results are given for nine asteroids previously reported from the Palmer Divide Observatory (PDO). The original images were re-measured to obtain new data sets using the latest version of MPO Canopus photometry software, analysis tools, and revised techniques for linking multiple observing runs covering several days to several weeks. Results that were previously not reported or were moderately different

Brian D. Warner

2011-01-01

301

Event Sequence Variability in Healthy Swallowing: Building on Previous Findings  

PubMed Central

This study builds on previous work by Kendall, Leonard and McKenzie, which investigated event sequence variability for 12 paired-events during swallowing by healthy volunteers. They identified four event pairs, which always occurred in a stereotyped order as well as a most-common occurring overall order of events during swallowing. In the current study, we investigate overall event sequencing and the same four paired-events in a sample of swallows by healthy, young (under 45 years old) volunteers. Data were collected during a 16-swallow lateral videofluoroscopy protocol, which included manipulations of bolus volume, barium density, bolus viscosity and swallow cueing. Our results agree with previous findings regarding the fact that variable event sequencing is found in healthy swallowing, and regarding the obligatory sequencing of two paired-events: movement of the arytenoids towards the base of the epiglottis begins prior to upper esophageal sphincter (UES) opening; and maximum hyo-laryngeal approximation occurs after UES opening. However, our data failed to replicate the previous finding of obligatory sequencing of maximum pharyngeal constriction after maximal UES distension and UES opening occurring before bolus arrival at the UES. The most-common observed overall event sequence reported by Kendall was observed in only 4/293 swallows in our dataset. Manipulations of bolus volume, bolus viscosity, barium concentration, swallow cueing and swallow repetitions could not completely account for differences observed between the two studies. PMID:24390702

Molfenter, Sonja M.; Leigh, Chelsea; Steele, Catriona M.

2015-01-01

302

[Fatal surgical extraction of cardiac resynchronisation therapy defibrillator leads in a context of endocarditis due to methicillin-resistant Staphylococcus epidermidis. A case report and review of literature].  

PubMed

A 82-year-old man equipped with a cardiac resynchronisation therapy defibrillator for dilated cardiomyopathy with normal coronary arteries, in complete atrioventricular block, develops six months after a change of the generator-pocket a severe endocarditis due to a methicillin-resistant Staphylococcus epidermidis with a large lead vegetation. After 4days of adapted antimicrobial therapy, a surgical device removal is realised with unfortunately a fatal end during extraction. This observation points out the severity of cardiovascular device infections in old and weak population, as well as the difficulty of treatment choices because of both infectious and rhythmic constraints. The lead extraction is a strong recommendation but the modality and timing of extraction are not consensual, especially in cardioverter defibrillator-dependent patients. Surgical removal remains an alternative to percutaneous lead extraction but with a higher operative risk. PMID:24836938

Verdier-Watts, F; Zouaghi, O; Berend, M; Wey, P-F; Farhat, F; Bonnefoy, E; Mioulet, D; Griffet, V

2015-02-01

303

Influenceable and Avoidable Risk Factors for Systemic Air Embolism due to Percutaneous CT-Guided Lung Biopsy: Patient Positioning and Coaxial Biopsy Technique—Case Report, Systematic Literature Review, and a Technical Note  

PubMed Central

Following the first case of a systemic air embolism due to percutaneous CT-guided lung biopsy in our clinic we analysed the literature regarding this matter in view of influenceable or avoidable risk factors. A systematic review of literature reporting cases of systemic air embolism due to CT-guided lung biopsy was performed to find out whether prone positioning might be a risk factor regarding this issue. In addition, a technical note concerning coaxial biopsy practice is presented. Prone position seems to have relevance for the development and/or clinical manifestation of air embolism due to CT-guided lung biopsy and should be considered a risk factor, at least as far as lesions in the lower parts of the lung are concerned. Biopsies of small or cavitary lesions in coaxial technique should be performed using a hemostatic valve. PMID:25431666

2014-01-01

304

Honeybee colony collapse due to Nosema ceranae in professional apiaries.  

PubMed

Honeybee colony collapse is a sanitary and ecological worldwide problem. The features of this syndrome are an unexplained disappearance of adult bees, a lack of brood attention, reduced colony strength, and heavy winter mortality without any previous evident pathological disturbances. To date there has not been a consensus about its origins. This report describes the clinical features of two professional bee-keepers affecting by this syndrome. Anamnesis, clinical examination and analyses support that the depopulation in both cases was due to the infection by Nosema ceranae (Microsporidia), an emerging pathogen of Apis mellifera. No other significant pathogens or pesticides (neonicotinoids) were detected and the bees had not been foraging in corn or sunflower crops. The treatment with fumagillin avoided the loss of surviving weak colonies. This is the first case report of honeybee colony collapse due to N. ceranae in professional apiaries in field conditions reported worldwide. PMID:23765741

Higes, Mariano; Martín-Hernández, Raquel; Garrido-Bailón, Encarna; González-Porto, Amelia V; García-Palencia, Pilar; Meana, Aranzazu; Del Nozal, María J; Mayo, R; Bernal, José L

2009-04-01

305

Malignant tumor-like gastric lesion due to Candida albicans in a diabetic patient treated with cyclosporin: a case report and review of the literature.  

PubMed

The gastrointestinal tract of healthy individuals is colonized by hundreds of saprophytes and mycetes, especially the Candida species, are habitual ones. Under certain conditions, the fungal flora may overgrow, resulting in lesions of the digestive mucosa which, rarely, can have a local diffusion and/or spread to the lympho-hematogenous system. Mycotic infections of the stomach can sometimes look like benign gastric ulcers. Here, we present the case report of a woman, aged 64, who presented with type II diabetes mellitus and psoriasis, on chronic treatment with cyclosporin A and with endoscopic evidence of an ulcerated, vegetating gastric lesion secondary to Candida albicans infection. Although strongly suggestive of malignancy, it completely healed after cyclosporin withdrawal and the administration of oral antifungal drugs. PMID:21904834

Mansueto, Pasquale; Pisciotta, Giuseppe; Tomasello, Giovanni; Cabibi, Daniela; Seidita, Aurelio; D'Alcamo, Alberto; Patti, Angelo Maria; Sprini, Delia; Carroccio, Antonio; Rini, Giovam Battista; Fede, Gaetana Di

2012-09-01

306

Optic atrophy and a Leigh-like syndrome due to mutations in the c12orf65 gene: report of a novel mutation and review of the literature.  

PubMed

Combined oxidative phosphorylation deficiency type 7 (COXPD7) is a rare disorder of mitochondrial metabolism that results in optic atrophy and Leigh syndrome-like disease. We describe 2 siblings with compound heterozygous mutations in the recently identified C12orf65 gene who presented with optic atrophy and mild developmental delays and subsequently developed bilateral, symmetric lesions in the brainstem reminiscent of Leigh syndrome. Repeat neuroimaging demonstrated reversibility of the findings in 1 sibling and persistent metabolic stroke in the other. This article highlights the phenotypic manifestations from a novel mutation in the C12orf65 gene and reviews the clinical presentation of the 5 other individuals reported to date who carry mutations in this gene. PMID:24284555

Heidary, Gena; Calderwood, Laurel; Cox, Gerald F; Robson, Caroline D; Teot, Lisa A; Mullon, Jennifer; Anselm, Irina

2014-03-01

307

A Fatal Spontaneous Gas Gangrene due to Clostridium perfringens during Neutropenia of Allogeneic Stem Cell Transplantation: Case Report and Literature Review  

PubMed Central

Most cases of gas gangrene caused by Clostridium species begin with trauma-related injuries but in rare cases, spontaneous gas gangrene (SGG) can occur when patients have conditions such as advanced malignancy, diabetes, or immunosuppression. Clostridium perfringens, a rare cause of SGG, exists as normal flora of skin and intestines of human. Adequate antibiotics with surgical debridement of infected tissue is the only curative therapeutic management. Mortality rate among adults is reported range of 67-100% and majority of deaths are occurred within 24 hours of onset. We experienced a case of SGG on the trunk, buttock and thigh in a neutropenic patient with acute lymphoblastic leukemia. His clinical course was rapid and fatal during pre-engraftment neutropenic period of allogeneic stem cell transplantation. PMID:25298910

Lee, Hae-Lim; Cho, Sung-Yeon; Ko, Yumi; Hyun, Ji In; Kim, Bo Kyoung; Seo, Jae Hyun; Lee, Jung Woo; Lee, Seok

2014-01-01

308

Secondary aortoduodenal fistula following endovascular repair of inflammatory abdominal aortic aneurysm due to Streptococcus anginosus infection: A case report and literature review?  

PubMed Central

INTRODUCTION Aortoenteric fistula is a rare but very serious complication of both surgical and endovascular abdominal aortic reconstruction. Since the advent of endovascular abdominal aortic aneurysm repair (EVAR), 20 cases of aortoduodenal fistula associated with aortic stent grafts have been reported.1 However, only a handful has been reported following inflammatory abdominal aortic aneurysm repair. It most commonly presents with bleeding, usually from the upper gastro-intestinal tract. With recent advances in the screening, diagnosis and management of abdominal aortic aneurysms either surgically or through an endovascular approach, the diagnosis of an aortoduodenal fistula in patients with gastro-intestinal bleeding must be suspected and excluded. PRESENTATION OF CASE We describe a case of secondary aortoduodenal fistula that occurred two and a half years following endovascular stent graft repair of an inflammatory abdominal aortic aneurysm. We also outline the emergency correction plan and the attempts at repair. DISCUSSION This case defies the general concept that patients with inflammatory abdominal aortic aneurysms are relatively immune to rupture. Although the presence of a peri-aneurysm thick inflammatory membrane decreases the possibility of rupture, these patients are more susceptible to other related complications such as aorto-enteric and aorto-caval fistulas.2 This case also demonstrates the peculiar presence of Streptococcus anginosus as the pathological organism leading to graft infection and subsequent fistula, as opposed to enterococci which are often found in endograft infection. CONCLUSION Aorto-enteric fistulas are associated with a grave prognosis. Early diagnosis is crucial and extra vigilance should be taken in cases of inflammatory AAA. PMID:25201477

Zaki, M.; Tawfick, W.; Alawy, M.; ElKassaby, M.; Hynes, N.; Sultan, S.

2014-01-01

309

"Spontaneous" CSF Fistula due to Transtegmental Brain Herniation in Combination with Signs of Increased Intracranial Pressure and Petrous Bone Hyperpneumatization: An Illustrative Case Report.  

PubMed

Background and Importance?Transtegmental brain herniation into the petrous bone is a rare cause of rhinoliquorrhea. Our case presents a combination of several typical clinical and imaging findings illustrating the ongoing etiologic discussion of such cerebrospinal fluid (CSF) fistulas. Clinical Presentation?A 53-year-old man presented with nasal discharge after a strong effort to suppress coughing. Imaging revealed a transtegmental herniation of parts of the inferior temporal gyrus into the petrous bone and in addition a combination of signs of chronically increased intracranial pressure and a hyperpneumatization of the petrous bone. The fistula was closed by a middle cranial fossa approach. Conclusion?The case illustrates the two main predisposing factors for development of petrous bone CSF fistulas: increased intracranial pressure and thinning of the tegmental roof due to extensive development of air cells. Because the CSF leakage repair does not change the underlying cause, patients have to be informed about the possibility of developing increased intracranial pressure and recurrences of brain herniations at other sites. PMID:25485224

Rivera, Diones; Fermin-Delgado, Rafael; Stoeter, Peter

2014-12-01

310

Wildlife Loss Estimates and Summary of Previous Mitigation Related to Hydroelectric Projects in Montana, Volume Three, Hungry Horse Project.  

SciTech Connect

This assessment addresses the impacts to the wildlife populations and wildlife habitats due to the Hungry Horse Dam project on the South Fork of the Flathead River and previous mitigation of theses losses. In order to develop and focus mitigation efforts, it was first necessary to estimate wildlife and wildlife hatitat losses attributable to the construction and operation of the project. The purpose of this report was to document the best available information concerning the degree of impacts to target wildlife species. Indirect benefits to wildlife species not listed will be identified during the development of alternative mitigation measures. Wildlife species incurring positive impacts attributable to the project were identified.

Casey, Daniel

1984-10-01

311

Global Distribution of Extreme Precipitation and High-Impact Landslides in 2010 Relative to Previous Years  

NASA Technical Reports Server (NTRS)

It is well known that extreme or prolonged rainfall is the dominant trigger of landslides worldwide. While research has evaluated the spatiotemporal distribution of extreme rainfall and landslides at local or regional scales using in situ data, few studies have mapped rainfall-triggered landslide distribution globally due to the dearth of landslide data and consistent precipitation information. This study uses a newly developed Global Landslide Catalog (GLC) and a 13-year satellite-based precipitation record from TRMM data. For the first time, these two unique products provide the foundation to quantitatively evaluate the co-occurrence of precipitation and landslides globally. Evaluation of the GLC indicates that 2010 had a large number of high-impact landslide events relative to previous years. This study considers how variations in extreme and prolonged satellite-based rainfall are related to the distribution of landslides over the same time scales for three active landslide areas: Central America, the Himalayan Arc, and central-eastern China. Several test statistics confirm that TRMM rainfall generally scales with the observed increase in landslide reports and fatal events for 2010 and previous years over each region. These findings suggest that the co-occurrence of satellite precipitation and landslide reports may serve as a valuable indicator for characterizing the spatiotemporal distribution of landslide-prone areas in order to establish a global rainfall-triggered landslide climatology. This study characterizes the variability of satellite precipitation data and reported landslide activity at the globally scale in order to improve landslide cataloging, forecasting and quantify potential triggering sources at daily, monthly and yearly time scales.

Kirschbaum, Dalia; Adler, Robert; Adler, David; Peters-Lidard, Christa; Huffman, George

2012-01-01

312

Assessment of predictive models for the failure of titanium and ferrous alloys due to hydrogen effects. Report for the period of June 16 to September 15, 1981  

SciTech Connect

The 1977 version of the Simpson-Puls-Dutton model appears to be the most amenable with respect to utilizing known or readily estimated quantities. The Pardee-Paton model requires extensive calculations involving estimated quantities. Recent observations by Koike and Suzuki on vanadium support the general assumption that crack growth in hydride forming metals is determined by the rate of hydride formation, and their hydrogen atmosphere-displacive transformation model is of potential interest in explaining hydrogen embrittlement in ferrous alloys as well as hydride formers. The discontinuous nature of cracking due to hydrogen embrittlement appears to depend very strongly on localized stress intensities, thereby pointing to the role of microstructure in influencing crack initiation, fracture mode and crack path. The initiation of hydrogen induced failures over relatively short periods of time can be characterized with fair reliability using measurements of the threshold stress intensity. The experimental conditions for determining K/sub Th/ and ..delta..K/sub Th/ are designed to ensure plane strain conditions in most cases. Plane strain test conditions may be viewed as a conservative basis for predicting delayed failure. The physical configuration of nuclear waste canisters may involve elastic/plastic conditions rather than a state of plane strain, especially with thin-walled vessels. Under these conditions, alternative predictive tests may be considered, including COD and R-curve methods. The double cantilever beam technique employed by Boyer and Spurr on titanium alloys offers advantages for examining hydrogen induced delayed failure over long periods of time. 88 references. (DLC)

Archbold, T.F.; Bower, R.B.; Polonis, D.H.

1982-04-01

313

A Case of Infant Botulism due to Neurotoxigenic Clostridium butyricum Type E Associated with Clostridium difficile Colitis  

Microsoft Academic Search

.   Reported here is the sixth case of intestinal toxemia botulism caused by Clostridium butyricum type E in Italy since 1984. In this case, the patient was concomitantly affected with colitis due to Clostridium difficile toxin. A review of previously reported cases revealed that some of these patients may also have had intestinal toxemia botulism\\u000a associated with Clostridium difficile colitis,

L. Fenicia; L. Da Dalt; F. Anniballi; G. Franciosa; S. Zanconato; P. Aureli

2002-01-01

314

Increasing Resistance of Coagulase-Negative Staphylococci in Total Hip Arthroplasty Infections: 278 THA-Revisions due to Infection Reported to the Norwegian Arthroplasty Register from 1993 to 2007  

PubMed Central

We investigated bacterial findings from intraoperative tissue samples taken during revision due to infection after total hip arthroplasty (THA). The aim was to investigate whether the susceptibility patterns changed during the period from 1993 through 2007. Reported revisions due to infection in the Norwegian Arthroplasty Register (NAR) were identified, and 10 representative hospitals in Norway were visited. All relevant information on patients reported to the NAR for a revision due to infection, including bacteriological findings, was collected from the medical records. A total of 278 revision surgeries with bacterial growth in more than 2 samples were identified and included. Differences between three 5-year time periods were tested by the chi-square test for linear trend. The most frequent isolates were coagulase-negative staphylococci (CoNS) (41%, 113/278) and Staphylococcus aureus (19%, 53/278). The proportion of CoNS resistant to the methicillin-group increased from 57% (16/28) in the first period, 1993–1997, to 84% (52/62) in the last period, 2003–2007 (P = 0.003). There was also significant increase in resistance for CoNS to cotrimoxazole, quinolones, clindamycin, and macrolides. All S. aureus isolates were sensitive to both the methicillin-group and the aminoglycosides. For the other bacteria identified no changes in susceptibility patterns were found. PMID:25371827

Langvatn, Håkon; Dale, Håvard; Schrama, Johannes Cornelis; Hallan, Geir; Sjursen, Haakon; Engesæter, Lars B.

2014-01-01

315

Neurological recovery after surgical treatment of giant cervical pseudomeningoceles extending to lumbar spine associated with previous brachial plexus injury.  

PubMed

The authors describe a case of 28-year-old man who presented with cervical myelopathy and lumbar radiculopathy due to the giant cervical pseudomeningocele extending to the lumbar spine at 10 years after previous brachial plexus injury. To evaluate the communicating tract between pseudomeningocele and subarachnoidal space, the multidetector-row helical CT with simultaneous myelography was performed preoperatively. The surgical treatment in the cervical spine included the resection of pseudomeningocele and the repair of dural defects communicating into the cyst following multi-level laminoplasty and foraminotomies. At 6 years after surgery, the significant neurologic recovery and complete obliteration of cysts in the whole spine area were maintained. This serves as the first report describing the significant neurologic recovery after the surgical treatment of giant cervical pseudomeningocele extending to the lumbar spine after previous brachial plexus injury. PMID:20383537

Kotani, Yoshihisa; Abumi, Kuniyoshi; Ito, Manabu; Terae, Satoshi; Hisada, Yukiyoshi; Minami, Akio

2010-07-01

316

Neurological recovery after surgical treatment of giant cervical pseudomeningoceles extending to lumbar spine associated with previous brachial plexus injury  

PubMed Central

The authors describe a case of 28-year-old man who presented with cervical myelopathy and lumbar radiculopathy due to the giant cervical pseudomeningocele extending to the lumbar spine at 10 years after previous brachial plexus injury. To evaluate the communicating tract between pseudomeningocele and subarachnoidal space, the multidetector-row helical CT with simultaneous myelography was performed preoperatively. The surgical treatment in the cervical spine included the resection of pseudomeningocele and the repair of dural defects communicating into the cyst following multi-level laminoplasty and foraminotomies. At 6 years after surgery, the significant neurologic recovery and complete obliteration of cysts in the whole spine area were maintained. This serves as the first report describing the significant neurologic recovery after the surgical treatment of giant cervical pseudomeningocele extending to the lumbar spine after previous brachial plexus injury. PMID:20383537

Abumi, Kuniyoshi; Ito, Manabu; Terae, Satoshi; Hisada, Yukiyoshi; Minami, Akio

2010-01-01

317

A previously unreported serious adverse event during balloon sinuplasty  

PubMed Central

Balloon sinuplasty is considered as a minimally invasive procedure for the treatment of chronic rhinosinusitis. In this case report we describe how a patient undergoing balloon sinuplasty sustained an intraoperative cardiac arrest with no cardiac history. Postoperative investigations were all normal. The patient was discharged on the first postoperative day and further outpatient tests were normal. We postulate that this event occurred due to profound vagal stimulation either on instrumentation of the maxillary mucosa or when the orbit was accidently breached during instrumentation of the right frontal recess. The authors conclude that balloon sinuplasty, despite being minimally invasive surgery, should be performed under the supervision of an anaesthesiologist with the ability of cardiac monitoring and immediate treatment because of possible arrhythmias. PMID:23362063

Hughes, Nadine; Bewick, Jessica; Van Der Most, Renee; O'Connell, Mike

2013-01-01

318

Emergency thyroidectomy: Due to acute respiratory failure  

PubMed Central

INTRODUCTION Giant cervical and mediastinal goiter may lead to acute respiratory failure caused by laryngotracheal compression and airway obstruction. Here, we present a case admitted to the emergency service with a giant goiter along with respiratory failure and poor general health status, which required urgent surgical intervention. PRESENTATION OF CASE A 71-year-old female admitted to the emergency room with shortness of breath and poor general health status resulting from a giant cervical swelling progressively increased during the last 7 years and constituted severe respiratory failure which has become severe in the last one month. A giant nodular goiter of the left thyroid lobe extending retrosternally, causing tracheal compression, limiting the neck movements was detected with clinical examination and bedside ultrasound. Emergency thyroidectomy was planned. Fiberoptic-assisted awake nasal intubation was performed in the operating room. Emergency total thyroidectomy was performed for the life-threatening respiratory failure. Postoperative period was uneventful. She was transferred from intensive care unit to the ward on postoperative day 3 and was discharged from the hospital on the postoperative 7th day. Benign multinodular hyperplasia was reported on the histopathological report. Patient was included in routine follow-up. DISCUSSION In the present case tracheal destruction due to compression of the giant goiter was found in agreement with previous reports. Emergency thyroidectomy was performed after awake intubation since it is a common surgical option for the treatment of giant goiter causing severe airway obstruction. CONCLUSION Respiratory failure due to giant nodular goiter is a life-threatening situation and should be treated immediately by performing awake endotracheal intubation following emergency total thyroidectomy. PMID:25437688

Bayhan, Zulfu; Zeren, Sezgin; Ucar, Bercis Imge; Ozbay, Isa; Sonmez, Yalcin; Mestan, Metin; Balaban, Onur; Bayhan, Nilufer Araz; Ekici, Mehmet Fatih

2014-01-01

319

Ten Year Overview of HCC FTE Enrollment: Fiscal Year 1976 to Fiscal Year 1985 [and] Thirteen Percent of HCC Students Have Earned Previous Degrees [and] Percent of Student Population by Age. Flash Facts IR Mini Reports; Volume 1, Numbers 1-3.  

ERIC Educational Resources Information Center

These mini-reports present summaries of data and research findings about the students of Howard Community College (HCC) in Maryland. In the first report, trends in full-time equivalent (FTE), credit, and continuing education enrollments are charted from 1976 to 1985, showing a 92% increase in total FTE enrollment. The second report focuses on HCC…

Radcliffe, Susan; And Others

320

The use of a tantalum-based Augmentation Patella in patients with a previous patellectomy  

Microsoft Academic Search

Patients with previous patellectomies for anterior knee pain syndrome, can remain symptomatic and develop osteoarthrosis or instability. We report our experience of the use of a novel implant to substitute for the absent native patella.Seven patients, with previous patellectomies, were treated with the Augmentation Patella (Zimmer, Allendale, USA). This implant was sutured to the patellar tendon, as part of a

Yune Kwong; Vikram V. Desai

2008-01-01

321

Previous Mental Health Service Utilization and Change in Clients' Depressive Symptoms  

ERIC Educational Resources Information Center

Although a potentially important factor in case conceptualization and treatment planning, the impact of previous treatment on subsequent counseling response has received little empirical attention. Using archival data, this study aimed to (a) report the prevalence of previous treatment utilization in a counseling population, (b) examine potential…

Boswell, James F.; McAleavey, Andrew A.; Castonguay, Louis G.; Hayes, Jeffrey A.; Locke, Benjamin D.

2012-01-01

322

27 CFR 26.55 - Previously approved formulas.  

Code of Federal Regulations, 2010 CFR

... false Previously approved formulas. 26.55 Section 26.55...RICO AND THE VIRGIN ISLANDS Formulas for Products From Puerto Rico § 26.55 Previously approved formulas. Any formula approved on Form 27-B...

2010-04-01

323

27 CFR 26.55 - Previously approved formulas.  

... false Previously approved formulas. 26.55 Section 26.55...RICO AND THE VIRGIN ISLANDS Formulas for Products From Puerto Rico § 26.55 Previously approved formulas. Any formula approved on Form 27-B...

2014-04-01

324

27 CFR 26.225 - Previously approved formulas.  

Code of Federal Regulations, 2011 CFR

... false Previously approved formulas. 26.225 Section 26.225...RICO AND THE VIRGIN ISLANDS Formulas for Products From the Virgin...26.225 Previously approved formulas. Any formula approved on Form 27-B...

2011-04-01

325

27 CFR 26.55 - Previously approved formulas.  

Code of Federal Regulations, 2012 CFR

... false Previously approved formulas. 26.55 Section 26.55...RICO AND THE VIRGIN ISLANDS Formulas for Products From Puerto Rico § 26.55 Previously approved formulas. Any formula approved on Form 27-B...

2012-04-01

326

27 CFR 26.225 - Previously approved formulas.  

Code of Federal Regulations, 2010 CFR

... false Previously approved formulas. 26.225 Section 26.225...RICO AND THE VIRGIN ISLANDS Formulas for Products From the Virgin...26.225 Previously approved formulas. Any formula approved on Form 27-B...

2010-04-01

327

27 CFR 26.225 - Previously approved formulas.  

Code of Federal Regulations, 2013 CFR

... false Previously approved formulas. 26.225 Section 26.225...RICO AND THE VIRGIN ISLANDS Formulas for Products From the Virgin...26.225 Previously approved formulas. Any formula approved on Form 27-B...

2013-04-01

328

27 CFR 26.55 - Previously approved formulas.  

Code of Federal Regulations, 2013 CFR

... false Previously approved formulas. 26.55 Section 26.55...RICO AND THE VIRGIN ISLANDS Formulas for Products From Puerto Rico § 26.55 Previously approved formulas. Any formula approved on Form 27-B...

2013-04-01

329

27 CFR 26.225 - Previously approved formulas.  

Code of Federal Regulations, 2012 CFR

... false Previously approved formulas. 26.225 Section 26.225...RICO AND THE VIRGIN ISLANDS Formulas for Products From the Virgin...26.225 Previously approved formulas. Any formula approved on Form 27-B...

2012-04-01

330

27 CFR 26.225 - Previously approved formulas.  

... false Previously approved formulas. 26.225 Section 26.225...RICO AND THE VIRGIN ISLANDS Formulas for Products From the Virgin...26.225 Previously approved formulas. Any formula approved on Form 27-B...

2014-04-01

331

27 CFR 26.55 - Previously approved formulas.  

Code of Federal Regulations, 2011 CFR

... false Previously approved formulas. 26.55 Section 26.55...RICO AND THE VIRGIN ISLANDS Formulas for Products From Puerto Rico § 26.55 Previously approved formulas. Any formula approved on Form 27-B...

2011-04-01

332

Cystic adventitial disease of the common femoral artery at a previous surgical dissection site.  

PubMed

Cystic adventitial disease (CAD) is a rare vascular disorder associated with nonatherosclerotic peripheral vessel disease and occurs when mucoid cysts in the adventitia compress the blood vessel. The underlying etiology and pathogenesis of CAD remain debatable as various theories have been suggested. This case is interesting because the cyst developed from the previous common femoral artery (CFA) dissection site. To our knowledge, this is the first report of CAD developed at a previous operation site. Thus, we report herein a case of CAD arising from a previous embolectomy dissection site in the CFA that was successfully treated with surgery. PMID:25463335

Park, Sun Jin; Park, Won Seo; Min, Sun Young; Kwon, Se Hwan; Park, Min Soo; Ahn, Hyung Joon

2015-02-01

333

Severe Left Atrioventricular Valve Regurgitation Due to Discontinuity between the Leaflets of the Aortic and Left Atrioventricular Valves in a Patient with Endocardial Cushion Defect: A Rare Case Report.  

PubMed

Discontinuities between the leaflets of the aortic and left atrioventricular valves are uncommon congenital malformations. The anomaly may be discovered during surgery without preoperative diagnosis. It represents a spectrum of anomalies that result from interruption of the normal development of the endocardial cushions during the fetal life. We describe a rare case of Down syndrome with transient complete atrioventricular block and discontinuity between the leaflets of the aortic and left atrioventricular valves without intervening fibrous band, leading to separation and detachment between them. It caused severe eccentric jet of regurgitation originated from left ventricular outflow tract and base of anterior leaflet of left atrioventricular valve into the left atrium. He underwent cardiopulmonary bypass, and the defect between left atrioventricular valve and aortic annuli was sewn. Permanent epicardial pacing was inserted during cardiac surgery. To the best of our knowledge, such a case has not been previously reported in the literature. PMID:25483555

Nabati, Maryam; Habibi, Valiolla; Soleimani, Aria; Shokri, Mojtaba

2014-12-01

334

Breast-conserving therapy after previous irradiation for lymphoma.  

PubMed

There is an increased risk of breast cancer in patients who have undergone radiation treatment for lymphoma. While this usually precludes further radiotherapy (RT), we report five women who received irradiation for lymphoma and who subsequently received breast-conserving therapy between 1995 and 2007 for early-stage breast cancer. There was an overlap between the two treatment fields in all patients. RT for lymphoma ranged between 29.8 and 40 grays (Gy). The interval between lymphoma and the diagnosis of breast cancer was 11-24 years. All five patients had lumpectomy and received subsequent RT (45 Gy in four patients, 50 Gy in the other). All tolerated breast RT well, and toxicity was limited to grade 1 events. All five patients were alive at last follow-up, and there was no local recurrence in the irradiated breast in any patient. We conclude that previous RT for lymphoma is not necessarily an absolute contraindication to breast-conserving therapy. PMID:19462230

Nguyen, Sonia K A; Dagnault, Anne

2010-12-01

335

[Case report of the first world death due to a new strain of human influenza A H1N1 virus and behavior of human influenzae in pregnant women].  

PubMed

Influenza A H1N1 is an acute respiratory illness caused by a new strain of H1N1. Human influenza is a subtype of influenza Avirus, from the family of Orthomyxoviridae. This strain is the cause of new influenza pandemic declared by the World Health Organization in June, 2009. This paper reports the first case occurred in Mexico: a 39-year-old woman with a history of diabetes mellitus type 2 and obesity grade II, which suffered atypical and aggressive pneumonia positive to coronavirus. Patient died 98 hours after her admission to the hospital unit. Due to the clinical presentation of the case, the doctors sent samples to the Instituto Nacional de Diagnóstico y Referencia Epidemiológica that sent an aliquot of the National Center for Immunization and Respiratory Diseases of theAgency of Public Health in Canada, that reported positivity to influenza virus, and catalogued it as a new global strain called influenza A virus H1N1. The notice of 229E/NL63 coronavirus and its relationship to the recent outbreaks of avian influenza in humans and the clinical presentation of the case were the epidemiological circumstances that prevented the nation epidemiology system to establish global containment strategies to prevent the spread of this emerging infection. The consequence was the declaration of WHO pandemic alert level 6. Its behavior in pregnancy, reported by Assistant General Direction of Epidemiology in Mexico, has placed this infection as a risk factor for women. PMID:23513403

Noguera Sánchez, Marcelo Fidias; Karchmer Krivitzky, Samuel; EsliRabadán, Martínez Cesar; Antonio Sánchez, Pedro

2013-01-01

336

Determining root correspondence between previously and newly detected objects  

SciTech Connect

A system that applies attribute and topology based change detection to networks of objects that were detected on previous scans of a structure, roadway, or area of interest. The attributes capture properties or characteristics of the previously detected objects, such as location, time of detection, size, elongation, orientation, etc. The topology of the network of previously detected objects is maintained in a constellation database that stores attributes of previously detected objects and implicitly captures the geometrical structure of the network. A change detection system detects change by comparing the attributes and topology of new objects detected on the latest scan to the constellation database of previously detected objects.

Paglieroni, David W.; Beer, N Reginald

2014-06-17

337

Macroglossia due to venous malformation  

Microsoft Academic Search

Massive vascular malformation involving tongue can cause significant functional impairment. In this report we describe a rare\\u000a case of extensive venous malformation involving tongue leading to obstructive sleep apnoea, inability to speak, eat, severe\\u000a discomfort due to exposure induced dryness and ulceration. Multimodality treatment approach comprising of sclerotherapy, electrocautery\\u000a and radiation therapy was used in this case.

T. S Anand; Ritu Mittal; T. B. Shashidhar; R. K. Sharma

2006-01-01

338

Transient allodynia following caudal lipoma excision: a case report.  

PubMed

Allodynia is the sensation of pain due to non-painful stimuli. It usually occurs due to destructive lesions of the spinal cord or peripheral nerves. Allodynia following intradural lipoma surgery has been reported previously. We herein report a case of allodynia developed after microsurgical caudal lipoma excision without associated spinal cord injury. PMID:22164320

Kalemci, Orhan; Ozer, Ercan; Yucesoy, Kemal; Arda, Mehmet Nuri; Erkin, Yüksel

2011-12-01

339

Transient Allodynia Following Caudal Lipoma Excision: A Case Report  

PubMed Central

Allodynia is the sensation of pain due to non-painful stimuli. It usually occurs due to destructive lesions of the spinal cord or peripheral nerves. Allodynia following intradural lipoma surgery has been reported previously. We herein report a case of allodynia developed after microsurgical caudal lipoma excision without associated spinal cord injury. PMID:22164320

Ozer, Ercan; Yucesoy, Kemal; Arda, Mehmet Nuri; Erkin, Yüksel

2011-01-01

340

Report on an outbreak of postinjection abscesses due to Mycobacterium abscessus, including management with surgery and clarithromycin therapy and comparison of strains by random amplified polymorphic DNA polymerase chain reaction.  

PubMed

An outbreak of postinjection abscesses occurred in Barranquilla, Colombia, and was associated with local injections of lidocaine given in a single physician's office. Over a 5-month period, 350 (18%) of approximately 2,000 injected patients developed localized cutaneous abscesses or cellulitis; of 210 abscess specimens that were cultured, 205 were positive for rapidly growing mycobacteria, subsequently identified as Mycobacterium abscessus. The source of the outbreak was not identified. M. abscessus could not be characterized by pulsed-field gel electrophoresis, but all isolates were identical in terms of drug and heavy metal resistance patterns and random amplified polymorphic DNA PCR profiles. We believe this is the first report of the use of this latter technique for investigation of an outbreak due to M. abscessus. Therapy with a combination of surgical excision and 3-6 months' administration of clarithromycin was successful for 95% of 148 patients treated in this manner; in contrast, therapy was successful for less than one-third of patients treated with surgery alone or clarithromycin alone. This is the largest of the nine known outbreaks of postinjection abscesses that have occurred due to rapidly growing mycobacteria and is the first in which an effective method of therapy was demonstrated. PMID:9195073

Villanueva, A; Calderon, R V; Vargas, B A; Ruiz, F; Aguero, S; Zhang, Y; Brown, B A; Wallace, R J

1997-06-01

341

Previous heat treatment inducing different plasma nitriding behaviors in martensitic stainless steels  

SciTech Connect

In this work we report a study of the induced changes in structure and corrosion behavior of martensitic stainless steels nitrided by plasma immersion ion implantation (PI{sup 3}) at different previous heat treatments. The samples were characterized by x-ray diffraction and glancing angle x-ray diffraction, scanning electron microscopy, energy dispersive x-ray spectroscopy, and potentiodynamic measurements. Depending on the proportion of retained austenite in the unimplanted material, different phase transformations are obtained at lower and intermediate temperatures of nitrogen implantation. At higher temperatures, the great mobility of the chromium yields CrN segregations like spots in random distribution, and the {alpha}{sup '}-martensite is degraded to{alpha}-Fe (ferrite). The nitrided layer thickness follows a fairly linear relationship with the temperature and a parabolic law with the process time. The corrosion resistance depends strongly on chromium segregation from the martensitic matrix, as a result of the formation of CrN during the nitrogen implantation process and the formation of Cr{sub x}C during the heat treatment process. Briefly speaking, the best results are obtained using low tempering temperature and low implantation temperature (below 375 deg. ) due to the increment of the corrosion resistance and nitrogen dissolution in the structure with not too high diffusion depths (about 5-10 {mu}m)

Figueroa, C. A.; Alvarez, F.; Mitchell, D. R. G.; Collins, G. A.; Short, K. T. [Australian Nuclear Science and Technology Organisation, Private Mail Bag 1, Menai, New South Wales 2234, Australia and Instituto de Fisica 'Gleb Wataghin', Unicamp, Campinas, Sao Paulo 13083-970 (Brazil); Instituto de Fisica 'Gleb Wataghin', Unicamp, Campinas, Sao Paulo 13083-970 (Brazil); Australian Nuclear Science and Technology Organisation, Private Mail Bag 1, Menai, New South Wales 2234 (Australia)

2006-09-15

342

DECOVALEX-THMC Task D: Long-Term Permeability/Porosity Changes inthe EDZ and Near Field due to THM and THC Processes in Volcanic andCrystaline-Bentonite Systems, Status Report October 2005  

SciTech Connect

The DECOVALEX project is an international cooperativeproject initiated by SKI, the Swedish Nuclear Power Inspectorate, withparticipation of about 10 international organizations. The name DECOVALEXstands for DEvelopment of COupled models and their VALidation againstExperiments. The general goal of this project is to encouragemultidisciplinary interactive and cooperative research on modelingcoupled processes in geologic formations in support of the performanceassessment for underground storage of radioactive waste. Three multi-yearproject stages of DECOVALEX have been completed in the past decade,mainly focusing on coupled thermal-hydrological-mechanicalprocesses.Currently, a fourth three-year project stage of DECOVALEX isunder way, referred to as DECOVALEX-THMC. THMC stands for Thermal,Hydrological, Mechanical, and Chemical processes. The new project stageaims at expanding the traditional geomechanical scope of the previousDECOVALEX project stages by incorporating geochemical processes importantfor repository performance. The U.S. Department of Energy (DOE) leadsTask D of the new DECOVALEX phase, entitled "Long-termPermeability/Porosity Changes in the EDZ and Near Field due to THC andTHM Processes for Volcanic and Crystalline-Bentonite Systems." In itsleadership role for Task D, DOE coordinates and sets the direction forthe cooperative research activities of the international research teamsengaged in Task D.

Birkholzer, J.; Rutqvist, J.; Sonnenthal, E.; Barr, D.

2005-11-01

343

Tsunami Heights along the Pacific Coast of Northern Honshu Recorded from the 2011 Tohoku and Previous Great Earthquakes  

NASA Astrophysics Data System (ADS)

The 2011 Tohoku earthquake generated a huge, destructive tsunami with coastal heights of up to 40 m recorded along northern Honshu. The Sanriku coast experienced similar tsunamis and damage from the 1896 and 1933 Sanriku earthquakes, whereas the only damaging tsunamis on both the Ibaraki and Chiba coasts in the previous century were from the 1960 and 2010 Chile earthquakes. We summarized 12 field surveys in which the height of the 2011 tsunami was recorded at 296 points, along with descriptions of the survey method, reliability, and accuracy. We then compared them with the above-mentioned tsunamis at locations for which specific measurements were given in previous reports. On the Sanriku coast, the 2011 tsunami heights are positively correlated with the previous Sanriku tsunamis, indicating that local variations resulting from the irregular coastline were more dominant factors than the earthquake location, type, or magnitude for near-field tsunamis. The correlations with the Chilean tsunami heights are less significant due to the differences between the local and trans-Pacific tsunamis. On the Ibaraki and Chiba coasts, the 2011 Tohoku and the two Chilean tsunami heights are positively correlated, showing the general decrease toward the south with small local variations such as large heights near peninsulas.

Tsuji, Yoshinobu; Satake, Kenji; Ishibe, Takeo; Harada, Tomoya; Nishiyama, Akihito; Kusumoto, Satoshi

2014-12-01

344

Yttrium-90 Radioembolization in Patients with Hepatocellular Carcinoma Who have Previously Received Sorafenib  

PubMed Central

Purpose: Yttrium-90 radioembolization (RE) is a locoregional therapy option for hepatocellular carcinoma (HCC). Sorafenib is a multikinase inhibitor used in HCC that can potentially affect the efficacy of RE by altering tumor vascularity or suppressing post-irradiation angiogenesis. The safety and efficacy of sorafenib followed by RE has not been previously reported. Materials and Methods: Patients with HCC who received RE after sorafenib were included in this retrospective review. Overall survival, toxicity, and maximal radiographic response and necrosis criteria were examined. Results: Ten patients (15 RE administrations) fit the inclusion criteria. All were Barcelona Clinic Liver Cancer (BCLC) stage C. Median follow-up was 16.5?weeks. Median overall survival and radiographic progression-free survival were 30 and 28?weeks, respectively. Significant differences in overall survival were seen based on Child-Pugh class (p?=?0.002) and radiographic response (p?=?0.009). Three patients had partial response, six had stable disease, and one had progressive disease. Grade 1 or 2 acute fatigue, anorexia, and abdominal pain were common. Three patients had Grade 3 ascites in the setting of disease progression. Two patients had Grade 3 biochemical toxicity. One patient was sufficiently downstaged following RE and sorafenib to receive a partial hepatectomy. Conclusion: Yttrium-90 RE in patients with HCC who have received sorafenib demonstrate acceptable toxicity and rates of radiographic response. However, the overall survival is lower than that reported in the literature on RE alone or sorafenib alone. This may be due in part to more patients in this study having advanced disease compared to these other study populations. Larger prospective studies are needed to determine whether the combination of RE and sorafenib is superior to either therapy alone. PMID:24416722

Rana, Nitesh; Ju, Andrew Wenhua; Bazylewicz, Michael; Kallakury, Bhaskar; He, Aiwu Ruth; Unger, Keith R.; Lee, Justin S.

2013-01-01

345

The Yellowstone magma reservoir is 50% larger than previously imaged  

NASA Astrophysics Data System (ADS)

Earlier tomographic studies of the Yellowstone crustal magma system have revealed a low P-wave crustal anomaly beneath the 0.64 Ma Yellowstone caldera that has been interpreted to be the magma reservoir of partial melt that provides the thermal energy for Yellowstone's youthful volcanic and hydrothermal systems. The Yellowstone seismic network has evolved over the last decade into a modern real-time volcano monitoring system that consists of 36 short-period, broadband, and borehole seismometers that cover the entire Yellowstone volcanic field and surrounding tectonic areas. Until recently, limited seismograph coverage did not provide for adequate resolution of the velocity structure northeast of the caldera, an area of the largest negative Bouguer gravity field of -60 mGal whose 3D density model reveals a shallow, low density body that extends ~20 km northeast of the caldera. Recent upgrades to the Yellowstone Seismic Network (YSN), including the addition of nine 3-component and broadband seismic stations providing much better ray coverage of the entire Yellowstone area with greater bandwidth data. This allows much-expanded and improved resolution coverage of the Yellowstone crustal velocity structure. We have compiled waveforms for the Yellowstone earthquake catalog from 1984-2011 with 45,643 earthquakes and 1,159,724 waveforms to analyze P-wave arrival times with an automatic picker based on an adaptive high-fidelity human mimicking algorithm. Our analysis reduced the data to the 4,520 best-located earthquakes with 48,622 P-wave arrival times to invert for the velocity structure. The resulting 3D P-wave model reveals a low Vp body (up to -7% ?Vp) that is interpreted to be the Yellowstone crustal magma reservoir and is ~50% larger than previously imaged. It extends as an oblong shaped anomalous body ~90 km NE-SW, ~20 km NE of the 0.64 Ma caldera, and up to 30 km wide and markedly shallowing from 15 km depth beneath the caldera to less than ~2 km deep northeast of the caldera. This body correlates with the large gravity anomaly described above implying a notable low density, low velocity body that we model to contain ~10% rhyolitic partial melt. Given the dimensions there are ~2,700 cubic km of melt in the magma reservoir, more than enough for continuing small to large volcanic eruptions. In addition, the distance of the anomaly NE beyond the mapped caldera boundary of ~20 km is consistent with relative motion of the N. America Plate across the Yellowstone plume in the last 640,000 years suggesting a progressive evolution of the magma body due to plate motion.

Farrell, J.; Smith, R. B.; Husen, S.

2013-12-01

346

Unexpected causes of pulmonary hypertension in a previously healthy Thai rural man with right-sided heart failure  

PubMed Central

Patient Male, 52 Final Diagnosis: Pulmonary hypertension Symptoms: Diarrhea • dyspnea • jaundice Medication: — Clinical Procedure: — Specialty: Endocrinology and Metabolic Objective: Unusual clinical course Background: Hyperthyroidism is one of the important causes of high-output failure and reversible pulmonary artery hypertension. Severe pulmonary artery hypertension is rarely found in associated with hyperthyroidism due to the small number of cases reported. We present an interesting case with multiple unexpected findings of the possible causes of severe pulmonary artery hypertension: hyperthyroidism, pulmonary embolism, and ostium secundum atrial septal defect. Case Report: We present the case of a previously healthy rural Thai man who progressively developed dyspnea on exertion, chronic diarrhea, and jaundice for the previous 3 months. Physical examination revealed right-sided predominate chronic heart failure with signs of pulmonary hypertension. The investigation demonstrated autoimmune hyperthyroidism, cholestatic jaundice, moderate tricuspid regurgitation, ostium secundum atrial septal defect, and severe pulmonary artery hypertension. After treatment with an anti-thyroid drug and closure of the ostium secundum atrial septal defect, his symptoms of jaundice and pulmonary artery pressure were completely resolved. Conclusions: Severe pulmonary artery hypertension may not solely be a result of hyperthyroidism. Further investigation for other causes is recommended. PMID:24808937

Angkananard, Teeranan; Chonmaitree, Piyanant; Petborom, Pichaya

2014-01-01

347

Antibodies against prM protein distinguish between previous infection with dengue and Japanese encephalitis viruses  

Microsoft Academic Search

BACKGROUND: In Southeast Asia, dengue viruses often co-circulate with other flaviviruses such as Japanese encephalitis virus, and due to the presence of shared antigenic epitopes it is often difficult to use serological methods to distinguish between previous infections by these flaviviruses. RESULTS: Convalescent sera from 69 individuals who were known to have had dengue or Japanese encephalitis virus infection were

Mary Jane Cardosa; Seok Mui Wang; Magdline Sia H Sum; Phaik Hooi Tio

2002-01-01

348

The Impact of Previous Traumatic Brain Injury on Health and Functioning: A TRACK-TBI Study  

PubMed Central

Abstract The idea that multiple traumatic brain injury (TBI) can have a cumulative detrimental effect on functioning is widely accepted. Most research supporting this idea comes from athlete samples, and it is not known whether remote history of previous TBI affects functioning after subsequent TBI in community-based samples. This study investigates whether a previous history of TBI with loss of consciousness (LOC) is associated with worse health and functioning in a sample of individuals who require emergency department care for current TBI. Twenty-three percent of the 586 individuals with current TBI in the Transforming Research and Clinical Knowledge in Traumatic Brain Injury study reported having sustained a previous TBI with LOC. Individuals with previous TBI were more likely to be unemployed (?2=17.86; p=0.000), report a variety of chronic medical and psychiatric conditions (4.75??2?24.16; p<0.05), and report substance use (16.35??2?27.57; p<0.01) before the acute injury, compared to those with no previous TBI history. Those with a previous TBI had less-severe acute injuries, but experienced worse outcomes at 6-month follow-up. Results of a series of regression analyses controlling for demographics and acute injury severity indicated that individuals with previous TBI reported more mood symptoms, more postconcussive symptoms, lower life satisfaction, and had slower processing speed and poorer verbal learning, compared to those with no previous TBI history. These findings suggest that history of TBI with LOC may have important implications for health and psychological functioning after TBI in community-based samples. PMID:23924069

Spielman, Lisa; Singh, Ayushi; Gordon, Wayne A.; Lingsma, Hester F.; Maas, Andrew I.R.; Manley, Geoffrey T.; Mukherjee, Pratik; Okonkwo, David O.; Puccio, Ava M.; Schnyer, David M.; Valadka, Alex B.; Yue, John K.; Yuh, Esther L.; Casey, and the TRACK-TBI Investigators including: Scott S.; Cooper, Shelly R.; Cheong, Maxwell; Hricik, Allison J.; Knight, Emily E.; Menon, David K.; Morabito, Diane J.; Pacheco, Jennifer L.; Sinha, Tuhin K.; Vassar, Mary J.

2013-01-01

349

Isolation of Oligotrophic Denitrifiers Carrying Previously Uncharacterized Functional Gene Sequences? †  

PubMed Central

Oligotrophic denitrifying bacteria, including those belonging to the genera Herbaspirillum, Azospirillum, and Bradyrhizobium, were obtained using a single-cell isolation technique. The taxonomic composition of the denitrifier population was similar to those assessed by previous culture-independent studies. The sequencing of nitrite reductase and N2O reductase genes of these strains revealed previously unknown links between 16S rRNA and the denitrification-functional gene phylogenies. In particular, we identified Bradyrhizobium strains that harbor nirS sequences previously detected only in culture-independent studies. PMID:21075882

Ishii, Satoshi; Ashida, Naoaki; Otsuka, Shigeto; Senoo, Keishi

2011-01-01

350

Successful surgical management for duodenum obstruction in a 66 year-old woman previously undiagnosed intestinal malrotation.  

PubMed

Intestinal malrotation is a congenital abnormality and is rarely seen in the adulthood. Most adult cases would be classified to the non-rotation type with Ladd's band and Ladd procedure is the treatment of choice. A 66 year-old woman admitted to our hospital due to duodenum obstruction. Several tests revealed that she had intestinal malrotation previously undiagnosed. Operative findings showed the fusion of duodenum with jejunum by the incomplete Treitz ligament. There was no Ladd's band and the right colon was unfixed. Dissection of the fusion completely released her symptom and she discharged without any complication. This is the first report of untypically intestinal malrotation in the adulthood without Ladd's band. PMID:24693686

Motomura, Takashi; Takahashi, Ikuo; Noguchi, Shinichi; Ochi, Tomohiro; Kajiwara, Yuichiro; Mano, Yohei; Nakanishi, Ryota; Fujinaka, Yoshihiko; Nishida, Kojiro; Yamashita, Yo-ichi; Saeki, Hiroshi; Kawanaka, Hirofumi; Morita, Masaru; Ikeda, Tetsuo; Soejima, Yuji; Nishizaki, Takashi; Maehara, Yoshihiko

2013-12-01

351

Previous Work on Image Segmentation As described in the previous chapter, the image segmentation problem can be stated as the  

E-print Network

Chapter 2 Previous Work on Image Segmentation As described in the previous chapter, the image segmentation problem can be stated as the division of an image into regions that separate different objects-of- the-art in image segmentation, and, together with the review chapter on perceptual grouping

Estrada, Francisco

352

Upon Further Review: V. An Examination of Previous Lightcurve Analysis from the Palmer Divide Observatory  

NASA Astrophysics Data System (ADS)

Updated results are given for nine asteroids previously reported from the Palmer Divide Observatory (PDO). The original images were re-measured to obtain new data sets using the latest version of MPO Canopus photometry software, analysis tools, and revised techniques for linking multiple observing runs covering several days to several weeks. Results that were previously not reported or were moderately different were found for 1659 Punkajarju, 1719 Jens, 1987 Kaplan, 2105 Gudy, 2961 Katsurahama, 3285 Ruth Wolfe, 3447 Burckhalter, 7816 Hanoi, and (34817) 2000 SE116. This is one in a series of papers that will examine results obtained during the initial years of the asteroid lightcurve program at PDO.

Warner, Brian D.

2011-01-01

353

Upon Further Review: IV. An Examination of Previous Lightcurve Analysis from the Palmer Divide Observatory  

NASA Astrophysics Data System (ADS)

Updated results are given for nine asteroids previously reported from the Palmer Divide Observatory (PDO). The original images were remeasured to obtain new data sets using the latest version of MPO Canopus photometry software, analysis tools, and revised techniques for linking multiple observing runs covering several days to several weeks. Results that were previously not reported or were moderately different were found for 573 Recha, 575 Renate, 605 Juvisia, 620 Drakonia, 687 Tinette, 787 Moskva, 983 Gunila, 1282 Utopia, and 1600 Vyssotsky. This is one in a series of papers that examines results obtained during the initial years of the asteroid lightcurve program at PDO.

Warner, Brian D.

2011-01-01

354

Upon Further Review: II. An Examination of Previous Lightcurve Analysis from the Palmer Divide Observatory  

NASA Astrophysics Data System (ADS)

Updated results are given for six asteroids previously reported from the Palmer Divide Observatory. The original images were remeasured to obtain new data sets using the latest version of MPO Canopus photometry software, analysis tools, and revised techniques for linking multiple observing runs covering several days to several weeks. Results that were previously not reported or had significantly different periods and/or amplitudes were found for 1329 Eliane, 1582 Martir, 2023 Asaph, 8041 Masumoto, (26853) 1992 UQ2, and (52387) 1993 OM7. This is the second in a series of papers that examines results obtained during the initial years of the asteroid lightcurve program at PDO.

Warner, Brian D.

2010-10-01

355

Upon Further Review: III. An Examination of Previous Lightcurve Analysis from the Palmer Divide Observatory  

NASA Astrophysics Data System (ADS)

Updated results are given for six asteroids previously reported from the Palmer Divide Observatory (PDO). The original images were remeasured to obtain new data sets using the latest version of MPO Canopus photometry software, analysis tools, and revised techniques for linking multiple observing runs covering several days to several weeks. Results that were previously not reported or were moderately different were found for 860 Ursina, 1146 Biarmia, 1158 Luda, 3431 Nakano, (10936) 1998 FN11, and (11424) 1999 LZ24. This is the third in a series of papers that examines results obtained during the initial years of the asteroid lightcurve program at PDO.

Warner, Brian D.

2011-01-01

356

Payload specialist Reinhard Furrer show evidence of previous blood sampling  

NASA Technical Reports Server (NTRS)

Payload specialist Reinhard Furrer shows evidence of previous blood sampling while Wubbo J. Ockels, Dutch payload specialist (only partially visible), extends his right arm after a sample has been taken. Both men show bruises on their arms.

1985-01-01

357

25 CFR 83.8 - Previous Federal acknowledgment.  

Code of Federal Regulations, 2010 CFR

...group must further have been identified by such sources as the same tribal entity that was previously...substantially continuous historical identification, by authoritative, knowledgeable external sources, of leaders and/or a governing body...

2010-04-01

358

25 CFR 83.8 - Previous Federal acknowledgment.  

Code of Federal Regulations, 2011 CFR

...group must further have been identified by such sources as the same tribal entity that was previously...substantially continuous historical identification, by authoritative, knowledgeable external sources, of leaders and/or a governing body...

2011-04-01

359

15 CFR 970.403 - Previous license and permit obligations.  

...OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES Certification of Applications § 970.403 Previous license...

2014-01-01

360

15 CFR 970.403 - Previous license and permit obligations.  

Code of Federal Regulations, 2012 CFR

...OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES Certification of Applications § 970.403 Previous license...

2012-01-01

361

15 CFR 970.403 - Previous license and permit obligations.  

Code of Federal Regulations, 2013 CFR

...OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES Certification of Applications § 970.403 Previous license...

2013-01-01

362

16. INTERIOR, SECOND FLOOR, DETAIL OF PREVIOUSLY EXTERIOR POST AT ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

16. INTERIOR, SECOND FLOOR, DETAIL OF PREVIOUSLY EXTERIOR POST AT EAST WALL, SHOWING NOTCHES FOR WEATHERBOARDS AND CRUDE FINISHING OF THE OAK FRAMING - Robeson-Williams Grist Mill, Roslyn, Nassau County, NY

363

14 CFR 47.33 - Aircraft not previously registered anywhere.  

Code of Federal Regulations, 2011 CFR

...Space 1 2011-01-01 2011-01-01 false Aircraft not previously registered anywhere. 47.33 Section...AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRCRAFT REGISTRATION Certificates of Aircraft...

2011-01-01

364

14 CFR 47.33 - Aircraft not previously registered anywhere.  

Code of Federal Regulations, 2013 CFR

...Space 1 2013-01-01 2013-01-01 false Aircraft not previously registered anywhere. 47.33 Section...AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRCRAFT REGISTRATION Certificates of Aircraft...

2013-01-01

365

14 CFR 47.33 - Aircraft not previously registered anywhere.  

...Space 1 2014-01-01 2014-01-01 false Aircraft not previously registered anywhere. 47.33 Section...AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRCRAFT REGISTRATION Certificates of Aircraft...

2014-01-01

366

14 CFR 47.33 - Aircraft not previously registered anywhere.  

Code of Federal Regulations, 2012 CFR

...Space 1 2012-01-01 2012-01-01 false Aircraft not previously registered anywhere. 47.33 Section...AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRCRAFT REGISTRATION Certificates of Aircraft...

2012-01-01

367

Placenta previa and Antepartum Hemorrhage after Previous Cesarean Section  

Microsoft Academic Search

A prospective study was conducted to determine the risk of placenta previa and unexplained antepartum hemorrhage after a previous cesarean section (CS). Of a total of 24,644 patients, 81 (0.33%) had a placenta previa which demanded abdominal delivery. The risk of placenta previa was 0.25% with an unscarred uterus and 1.22% in patients with one or more previous CS (the

Thorkild F. Nielsen; Henrik Hagberg; Ulf Ljungblad

1989-01-01

368

Acute generalized exanthematous pustulosis due to tetrazepam.  

PubMed

Tetrazepam is a benzodiazepine that is widely used in Spain as a muscle relaxant, with occasional cutaneous side effects. We report a patient who developed a generalized pruriginous cutaneous reaction compatible with acute generalized exanthematous pustulosis (AGEP) due to tetrazepam. Patch tests with bromazepam, diazepam, and tetrazepam were negative at 48 and 72 hours; however, the tetrazepam patch showed a positive reaction at 10 days. Immunohistochemical studies revealed a mononuclear infiltrate composed of CD4+ and CD8+ T lymphocytes. Analysis of interleukin (IL) 8 expression by quantitative polymerase chain reaction revealed increased IL-8 mRNA levels in patch test-positive skin. Lymphoblast transformation test (LTT) was positive with tetrazepam but not with diazepam. Positive patch test and LTT suggested that tetrazepam-specific lymphocytes might be responsible for a T cell-mediated reaction. These results support previous data suggesting an important role for IL-8 and drug-specific T cells in the pathogenesis ofAGEP and imply that the reaction was specific to tetrazepam with no cross-reactivity to other benzodiazepines. PMID:18447141

Thomas, E; Bellón, T; Barranco, P; Padial, A; Tapia, B; Morel, E; Alves-Ferreira, J; Martín-Esteban, M

2008-01-01

369

Microbunching Instability due to Bunch Compression  

SciTech Connect

Magnetic bunch compressors are designed to increase the peak current while maintaining the transverse and longitudinal emittances in order to drive a short-wavelength free electron laser (FEL). Recently, several linac-based FEL experiments observe self-developing micro-structures in the longitudinal phase space of electron bunches undergoing strong compression [1-3]. In the mean time, computer simulations of coherent synchrotron radiation (CSR) effects in bunch compressors illustrate that a CSR-driven microbunching instability may significantly amplify small longitudinal density and energy modulations and hence degrade the beam quality [4]. Various theoretical models have since been developed to describe this instability [5-8]. It is also pointed out that the microbunching instability may be driven strongly by the longitudinal space charge (LSC) field [9,10] and by the linac wakefield [11] in the accelerator, leading to a very large overall gain of a two-stage compression system such as found in the Linac Coherent Light Source (LCLS) [12]. This paper reviews theory and simulations of microbunching instability due to bunch compression, the proposed method to suppress its effects for short-wavelength FELs, and experimental characterizations of beam modulations in linear accelerators. A related topic of interests is microbunching instability in storage rings, which has been reported in the previous ICFA beam dynamics newsletter No. 35 (http://wwwbd. fnal.gov/icfabd/Newsletter35.pdf).

Huang, Zhirong; Wu, Juhao; /SLAC; Shaftan, Timur; /Brookhaven

2005-12-13

370

Parkinsonism associated with obstructive hydrocephalus due to idiopathic aqueductal stenosis  

PubMed Central

Two cases of parkinsonism after recurrent obstructive hydrocephalus due to idiopathic aqueductal stenosis are reported. In both patients an extrapyramidal syndrome was noted in the absence of contemporaneous evidence of hydrocephalus or shunt failure. One of the patients underwent a shunt operation, but showed no clinical improvement. However, both patients improved after the administration of dopaminergic therapy. The seven previously reported cases of this syndrome were reviewed and it is concluded that the prognosis of the parkinsonism is good, usually with total, or near total, resolution. It is recommended that if a patient with idiopathic aqueduct stenosis develops hydrocephalus or evidence of shunt malfunction in association with acute parkinsonism their shunt should be replaced. If there is no evidence of hydrocephalus or shunt malfunction they should initially be treated with domaminergic medication.?? PMID:9598684

Zeidler, M; Dorman, P; Ferguson, I; Bateman, D

1998-01-01

371

Report to the CCT on COOMET comparison COOMET.T-K3.1 (previously COOMET.T-S1): Key regional comparison of the national standards of temperature in the range from the triple point of water to the freezing point of zinc  

NASA Astrophysics Data System (ADS)

In the framework of the CIPM MRA, a first COOMET comparison "Comparison of the ITS-90 realizations in the range from 0.01 °C to 429.7485 °C (from the triple point of water to the freezing point of zinc)", registered in the KCDB under the identifier "COOMET.T-K3", was carried out in 2005-2007. Four national metrology institutes took part in this comparison: VNIIM (Russian Federation), SMU (Slovakia), BelGIM (Republic of Belarus) and NSC IM (Ukraine), and two of them (VNIIM and SMU) ensured the linkage with key comparisons CCT-K3 and CCT-K4, in order to disseminate the metrological equivalence to the measurement standards of NSC IM and BelGIM. NSC IM, however, had to withdraw its results, and at the meeting of Technical Committee T-10 of COOMET it was decided to carry out a supplementary bilateral comparison between VNIIM and the NSC IM for realization of the ITS-90 in the same range of temperature. This was registered in the KCDB under the identifier COOMET.T-S1 and measurements were performed in 2008-2009. From the results presented in this report, it is possible to draw the conclusion that the COOMET supplementary comparison COOMET.T-S1 demonstrates the CMC uncertainties claimed by the NSC IM for the melting point of gallium 0.236 mK (k = 2), and the freezing points of indium 1.040 mK (k = 2), tin 0.858 mK (k = 2) and zinc 0.944 mK (k = 2). In September 2012 the Working Group on key Comparisons (WG 7) of the CCT upgraded this comparison to a COOMET key comparison of the 'CCT-K3' type. It is now identified as COOMET.T-K3.1. In April 2013 this report was superseded by item 03006 in the Technical Supplement of 2013. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

Pokhodun, A. I.

2010-01-01

372

Comparison of the efficacy and tolerability of solifenacin succinate with or without previous use of trospium chloride.  

PubMed

Overactive bladder syndrome (OBS) is described as urinary urgency with or without incontinence, usually with increased daytime frequency and nocturia in the absence of another identifiable pathological process. Nowadays and despite other alternative therapies, the mainstay of OBS is still the pharmacological approach, mainly with anti-muscarinic drugs. To compare the efficacy of a 30-day solifenacin succinate (5 mg OD) treatment with or without previous medication with trospium chloride, a prostective open, two-arm, parallel group study was conducted for 5 weeks in 40 patients with OBS. The primary endpoint was patient self-assessment of improvement after 30 days of medication. Secondary endpoints included the reduction of the daily number of voids and urgency or involuntary leakage episodes. Adverse reactions and therapeutic stoppage were also evaluated. To be included in the trospium chloride treatment group, patients were required to have been treated with such drug for 1 to 6 months before the present study. Evaluation and efficacy assessment were accomplished using a 3-day bladder diary and an urgency severity scale (USS). Safety assessment was done by recording all the patients' complaints after starting medication. A total of 40 patients were enrolled for this study, 19 without previous medication and 21 who had already tried trospium chloride. Two patients from the non-previous medication group were excluded. Globally, there was a statistically significant reduction for the USS (2.73-->1.73), the daily number of voids (9.5-->7.0), of urgency episodes (9.1-->4.0) and of involuntary leakage episodes (3.6-->1.0) over the 24 h. Six patients had no improvement, four from the previous trospium chloride group and two from the non-previous medication group. Three patients reported side effects, two cases of dry mouth and one case of constipation. One patient dropped out of the treatment due to an unspecified intolerance. Solifenacin succinate 5 mg seems to be effective concerning patients' self-assessment of improvement and decrease in the mean number of daily voids, urgency episodes and incontinence episodes. This was reported both in patients who have already been medicated with trospium chloride and those who have never taken any kind of medication. Regarding side effects, solifenacin is quite well-tolerated in both groups. PMID:17211528

Metello, J; Nogueira, B; Torgal, M; Colaço, J; Vieira, A; Gonçalves, V; Retto, H

2007-09-01

373

Traumatic Endophthalmitis due to Cellulosimicrobium cellulans  

PubMed Central

Purpose. To report a case of traumatic endophthalmitis due to Cellulosimicrobium cellulans. Design. Case report. Methods. Retrospective chart review. Results. To our knowledge, this is the first report of traumatic endophthalmitis due to C. cellulans, which did not respond to intravitreal antibiotics or repeat vitrectomy and ultimately led to the discovery of an occult intraocular foreign body. Conclusions. C. cellulans is a rare cause of endophthalmitis. Greater awareness of this bacterium in the ophthalmic literature as a cause of endophthalmitis and its association with foreign bodies may allow earlier and more purposeful intervention in future cases. PMID:22606461

Jaru-ampornpan, Pimkwan; Agarwal, Anita; Midha, Narinder K.; Kim, Stephen J.

2011-01-01

374

Traumatic Endophthalmitis due to Cellulosimicrobium cellulans.  

PubMed

Purpose. To report a case of traumatic endophthalmitis due to Cellulosimicrobium cellulans. Design. Case report. Methods. Retrospective chart review. Results. To our knowledge, this is the first report of traumatic endophthalmitis due to C. cellulans, which did not respond to intravitreal antibiotics or repeat vitrectomy and ultimately led to the discovery of an occult intraocular foreign body. Conclusions. C. cellulans is a rare cause of endophthalmitis. Greater awareness of this bacterium in the ophthalmic literature as a cause of endophthalmitis and its association with foreign bodies may allow earlier and more purposeful intervention in future cases. PMID:22606461

Jaru-Ampornpan, Pimkwan; Agarwal, Anita; Midha, Narinder K; Kim, Stephen J

2011-01-01

375

NASA FORM 1018 SEP 03 PREVIOUS EDITIONS ARE OBSOLETE. (See instructions before completing this form.)  

E-print Network

NASA FORM 1018 SEP 03 PREVIOUS EDITIONS ARE OBSOLETE. (See instructions before completing this form.) NASA Property in the Custody of Contractors (NFS Subpart 1845.71) a. DEPUTY CHIEF FINANCIAL OFFICER, First, Middle Initial) CONTRACTOR REPRESENTATIVE: This report was prepared under NASA requirements from

Myers, Lawrence C.

376

Uveitis with occult choroiditis due to Mycobacterium kansasii: limitations of interferon-gamma release assay (IGRA) tests (case report and mini-review on ocular non-tuberculous mycobacteria and IGRA cross-reactivity).  

PubMed

Ocular tuberculosis is difficult to diagnose but should be suspected when uveitis fails to respond to inflammation suppressive therapy. Interferon-gamma release assays (IGRAs) represent a substantial help to diagnose suspected ocular tuberculosis especially in non-endemic areas. Indocyanine green angiography (ICGA) is able to detect clinically silent choroiditis that, when associated with a positive IGRA test, should lead the clinician to suspect ocular tuberculosis, warranting specific therapy. The fact that IGRA tests can also react with some atypical strains of mycobacteria is not always known. We report here a case with resistant post-operative inflammation that presented with occult ICGA-detected choroiditis and a positive IGRA test that was most probably due to the non-tuberculous mycobacterium (NTM) Mycobacterium kansasii. A 66 year-old man presented with a resistant cystoid macular oedema (CMO) in his left eye after combined cataract and epiretinal membrane surgery. At entry, his best-corrected visual acuity (BCVA) was 0.5 for far and near OS. Intraocular inflammation measured by laser flare photometry was elevated in the left eye (54.4 ph/ms) and also in the right eye (50.9 ph/ms). Four subTenon's injections of 40 mg of triamcinolone did not produce any substantial improvement. Therefore a complete uveitis work-up was performed. Fluorescein angiography showed CMO OS and ICGA showed numerous hypofluorescent dots and fuzziness of choroidal vessels in both eyes. Among performed laboratory tests, the QuantiFERON®-TB Gold test was positive. After a pulmonological examination disclosing a right upper lobe infiltrate, the patient was started on a triple anti-tuberculous therapy. Bronchial aspirate, obtained during bronchoscopy, was Ziehl-positive and culture grew M. kansasii. Nine months later, BCVA OS increased to 1.0 and flare decreased to 40.2 ph/ms. The CMO OS resolved angiographically and did not recur with a macula still slightly thickened on OCT. Suspected ocular tuberculosis based on clinical findings and a positive IGRA test can, in rare instances, be due to atypical mycobacteria that also produce positive IGRA tests such as M. kansasii, M. szulgai, M. gordonae, M. flavescens and M. marinum. In our case failure to isolate the atypical mycobacterium would not have had negative therapeutic consequences, as M. kansasii is sensitive to the standard anti-tuberculous treatments, which is not the case with other NTMs. PMID:22661050

Kuznetcova, Tatiana I; Sauty, Alain; Herbort, Carl P

2012-10-01

377

Factors affecting successful outcome from ICSI in men following previous vasectomy.  

PubMed

There are conflicting reports as to whether the interval between vasectomy and surgical sperm retrieval (SSR) for intra-cytoplasmic sperm injection (ICSI) is related to clinical pregnancy (CPR), and live birth (LBR), rates. This study aimed to evaluate factors that may influence the outcome of ICSI in males with secondary azoospermia due to previous vasectomy. We analysed the medical records of 198 azoospermic males following vasectomy who underwent percutaneous epididymal sperm aspiration (PESA) and/or testicular sperm extraction (TeSE), between 1997 and 2005 by a single urologist, and whose sperm was subsequently frozen for use in an IVF treatment programme on their partner's behalf. Hundred and forty-four (73%) males had a positive PESA, and the remaining 54 (27%) had a positive TeSE. Forty-four percent of males with no clinical evidence of epididymal distension still had epididymal sperm retrieved successfully. Hundred and twenty-eight patients proceeded with ICSI, and a total of 237 cycles were performed. The CPR and LBR overall were 29 and 27%, respectively. Using logistic regression there was no association between time since vasectomy and CPR (P = 0.17) or LBR (P = 0.31). A history of an attempted reversal of vasectomy did not negatively affect retrieval rates or CPR and LBR. The success of SSR and the outcome of ICSI, using frozen sperm, are independent of male age and time since vasectomy. Epididymal sperm may be retrieved in over 40% of men in whom there is no clinical evidence of epididymal distension. PMID:17609963

Bromage, Stephen J; Douglas, Jamie; Falconer, Debbie A; Lieberman, Brian A; Payne, Stephen R

2007-10-01

378

New Strategies for Cultivation and Detection of Previously Uncultured Microbes  

Microsoft Academic Search

An integrative approach was used to obtain pure cultures of previously uncultivated members of the divi- sions Acidobacteria and Verrucomicrobia from agricultural soil and from the guts of wood-feeding termites. Some elements of the cultivation procedure included the following: the use of agar media with little or no added nutrients; relatively long periods of incubation (more than 30 days); protection

Bradley S. Stevenson; Stephanie A. Eichorst; John T. Wertz; Thomas M. Schmidt; John A. Breznak

2004-01-01

379

I. INTRODUCTION Previous research in water treatment has been  

E-print Network

I. INTRODUCTION Previous research in water treatment has been varied and extensive. In the past, water treatment research included remote plasma processes, such as ozone, UV and electron processes the knowledge gleaned from past research, PAED seems to be a viable water treatment option. PAED may provide

McMaster University

380

Guidance on Microbial Contamination in Previously Flooded Outdoor Areas  

E-print Network

contamination after a flood event. Chemical contamination issues associated with flood events are not addressedGuidance on Microbial Contamination in Previously Flooded Outdoor Areas Environmental Health Buford Highway NE (F-60) Atlanta, GA 30341 March 2011 #12;2 Guidance on Microbial Contamination

381

Betaine distribution in the Scrophulariaceae and some previously included families  

Microsoft Academic Search

Aerial parts of 49 species, distributed in 39 genera, all previously included in Scrophulariaceae, but now distributed in several families, have been examined for the presence of betaines. Glycinebetaine was detected in all the plants, but the yield was always low, varying from 0.001% (based on dry weight) from Rhodochitonsanguineum to 0.2% from Rhinanthus minor. Trigonelline was also found in

Gerald Blunden; Asmita V. Patel; Nigel Armstrong

2003-01-01

382

Endoscopic Retrograde Cholangiopancreatography in Patients with Previous Acute Coronary Syndrome  

PubMed Central

Background/Aims Endoscopic retrograde cholangiopancreatography (ERCP) is considered a high-risk procedure in patients with previous acute coronary syndrome (ACS); however, clinical studies are rare in the literature. The aim of this study was to investigate the safety and efficacy of ERCP in patients with previous ACS. Methods We retrospectively reviewed the medical records of patients with previous ACS who underwent ERCP between January 2007 and August 2012. The clinical characteristics, ERCP diagnoses, treatment results, and complications were analyzed. Results Fifty patients underwent ERCP an average of 41.6 months after ACS. The most common indication for ERCP was calculous cholangitis. After deep biliary cannulation, endoscopic sphincterotomy, biliary stone removal and endoscopic biliary drainage were successfully performed. Immediate postsphincterotomy bleeding occurred in seven patients, which was successfully controlled using endoscopic therapy. Elevation of cardiac troponin I levels were observed in three patients (6%) before ERCP, and all of these patients were diagnosed with pancreatobiliary disease combined with recurrent ACS, which was treated with coronary artery stent insertion (n=2) and balloon angioplasty (n=1). Conclusions Therapeutic ERCP is effective and safe in patients with previous ACS. Cardiac troponin I elevation should be considered a warning sign for recurrent ACS in patients who undergo ERCP. PMID:25368756

Koh, Han-Ra; Park, Chang-Hwan; Chung, Min-Woo; Park, Seon-Young; Hong, Young-Joon; Jeong, Myung-Ho; Kim, Hyun-Soo; Choi, Sung-Kyu; Rew, Jong-Sun

2014-01-01

383

September 4, 2003 |Previous Next Rooting out the cheats  

E-print Network

September 4, 2003 |Previous Next Rooting out the cheats Crime doesn't pay for nitrogen good behavior among their rhizobia by imposing sanctions against cheats. cheat the system University," says Denison. In the September 4 , Kiers et al. show that the soybean discourages cheating by its

West, Stuart

384

Tocilizumab-induced neutropenia in rheumatoid arthritis patients with previous history of neutropenia: case series and review of literature.  

PubMed

One of the adverse events of tocilizumab (TCZ) is a transient, dose-dependent neutropenia. The recommendations of the Summary of Product Characteristics state that this neutropenia should be managed according to the absolute neutrophil count (ANC). However, the approach to a patient who had a history of neutropenia induced by previous DMARDs and developed TCZ-induced neutropenia remains unclear. We would like to report a series of four patients with rheumatoid arthritis who developed Grade 2 neutropenia (ANC 1-1.5 × 10(9)/L) following intravenous TCZ treatment at a dose of 8 mg/kg. All of them had a previous history of neutropenia (Grade 2 or Grade 3) due to Etanercept (three patients) and Sulfasalazine (one patient). Therefore, we decided to decrease the TCZ dosage by 10-20 % approximately. Reducing of the dosage did not have any influence on the efficacy of TCZ, and all of our patients remained in clinical remission. The mechanisms underlying neutropenia induced by Tocilizumab, Etanercept and Sulfasalazine are also discussed in this article. PMID:25403696

Shovman, O; Shoenfeld, Y; Langevitz, P

2015-02-01

385

Abdominal wall endometriosis: case report.  

PubMed

Abdominal wall endometriosis, also known as scar endometrioma, is a rare condition, in most cases occurring after previous cesarean section or pelvic surgery. The incidence of scar endometrioma is estimated to 0.03%-1.5% of all women with previous cesarean delivery. The predominant clinical picture is cyclic pain. Due to a wide range of mimicking conditions and a relative rarity, a significant delay is often observed from the onset of symptoms to proper treatment. We report on a case of a 36-year-old patient with scar endometrioma after two previous cesarean deliveries. The possible diagnostic pitfalls and treatment options are discussed. PMID:23115952

Eljuga, Damir; Klari?, Petar; Bolanca, Ivan; Grbavac, Ivan; Kuna, Krunoslav

2012-06-01

386

Respiratory manifestations due to nickel  

PubMed Central

Summary Nickel sulphate more frequently determines allergic dermatitis due to contact (contact eczema); less known are nasal inflammation (rhinitis) and bronchial asthma caused by nickel sulphate. Sporadic cases, often related to patients’ work have been reported in the literature. The research described herein refers to 20 patients presenting clear nickel allergy with rhinitis (associated in 11 cases with asthma). The patients, all females, revealed positivity to this kind of allergy: patch test, prick tests with nickel sulphate, nasal provocation test by nickel sulphate, computed tomography of paranasal sinuses, spirometry and bronchial provocation test with metacholine, oral provocation test with nickel sulphate were employed. A strict long-term diet with food with low nickel content (2-4 months at least) led to a progressive reduction of nasal symptoms (rhinorrea, sneezing, nasal obstruction) and an improvement in bronchial symptoms and functional parameters. PMID:16116834

Brera, S; Nicolini, A

2005-01-01

387

Previously Unrecognized Large Lunar Impact Basins Revealed by Topographic Data  

NASA Technical Reports Server (NTRS)

The discovery of a large population of apparently buried impact craters on Mars, revealed as Quasi- Circular Depressions (QCDs) in Mars Orbiting Laser Altimeter (MOLA) data [1,2,3] and as Circular Thin Areas (CTAs) [4] in crustal thickness model data [5] leads to the obvious question: are there unrecognized impact features on the Moon and other bodies in the solar system? Early analysis of Clementine topography revealed several large impact basins not previously known [6,7], so the answer certainly is "Yes." How large a population of previously undetected impact basins, their size frequency distribution, and how much these added craters and basins will change ideas about the early cratering history and Late Heavy Bombardment on the Moon remains to be determined. Lunar Orbiter Laser Altimeter (LOLA) data [8] will be able to address these issues. As a prelude, we searched the state-of-the-art global topographic grid for the Moon, the Unified Lunar Control Net (ULCN) [9] for evidence of large impact features not previously recognized by photogeologic mapping, as summarized by Wilhelms [lo].

Frey, Herbert V.

2008-01-01

388

Pregnancy outcome after induction of labor in women with previous cesarean section.  

PubMed

Abstract Objective: As conflicting data exist concerning the safety of induction of labor (IoL) in women with previous single lower segment cesarean section (CS), we aimed to assess pregnancy outcome following IoL in such patient population. Methods: All singleton pregnancies with previous single CS which underwent IoL during 2008-2012 were included (study group). Their pregnancy outcome was compared to those pregnancies with previous single CS that admitted with spontaneous onset of labor (control group). Results: Overall, 1898 pregnancies were eligible, of them, 259 underwent IoL, and 1639 were admitted with spontaneous onset of labor. Parity, gestational age at delivery and birthweight were similar. Women in the study group were more likely to undergo CS mainly due to labor dystocia (8.1 versus 3.7%, p?due to non-reassuring fetal heart rate was similar. No difference was found in the rate of uterine rupture/dehiscence. Short-term neonatal outcome was similar between the groups. On multivariable logistic regression analysis, IoL was not independently associated with uterine rupture (OR 1.33, 95% C.I 0.46-3.84, p?=?0.59). Conclusion: Our data suggest that IoL in women with one previous low segment CS neither increases the risk of uterine rupture nor adversely affects immediate neonatal outcome. PMID:24749798

Ashwal, Eran; Hiersch, Liran; Melamed, Nir; Ben-Zion, Maya; Brezovsky, Alex; Wiznitzer, Arnon; Yogev, Yariv

2014-05-22

389

Contributions of attentional style and previous experience to 4-month-old infants' categorization.  

PubMed

We examined how infants' categorization is jointly influenced by previous experience and how much they shift their gaze back-and-forth between stimuli. Extending previous findings reported by Kovack-Lesh, Horst, and Oakes (2008), we found that 4-month-old infants' (N = 122) learning of the exclusive category of cats was related to whether they had cats at home and how much they shifted attention between two available stimuli during familiarization. Individual differences in attention assessed in an unrelated task were not related to their categorization. Thus, infants' learning is multiply influenced by past experience and on-line attentional style. PMID:22523478

Kovack-Lesh, Kristine A; Oakes, Lisa M; McMurray, Bob

2012-05-01

390

Contributions of attentional style and previous experience to 4-month-old infants’ categorization  

PubMed Central

We examined how infants’ categorization is jointly influenced by previous experience and how much they shift their gaze back-and-forth between stimuli. Extending previous findings reported by Kovack-Lesh, Horst, and Oakes (2008), we found that 4-month-old infants’ (N = 122) learning of the exclusive category of cats was related to whether they had cats at home and how much they shifted attention between two available stimuli during familiarization. Individual differences in attention assessed in an unrelated task were not related to their categorization. Thus, infants’ learning is multiply influenced by past experience and on-line attentional style. PMID:22523478

Kovack-Lesh, Kristine A.; Oakes, Lisa M.; McMurray, Bob

2011-01-01

391

Uterine arteriovenous malformation caused by intrauterine instrumentation for laparoscopic surgery due to left tubal pregnancy  

PubMed Central

Uterine arteriovenous malformation (AVM) is a rare entity in gynecology with fewer than 100 cases reported in the literature. Due to abnormal connection between arteries and veins without an intervening capillary system, recurrent and profuse vaginal bleeding is the most common symptom which can be potentially life-threatening. Uterine AVM can be either congenital or acquired. Acquired AVM is reported as a consequence of previous uterine trauma such as curettage procedures, caesarean section or pelvic surgery. It is also associated with infection, retained product of conception, gestational trophoblastic disease, malignancy and exposure to diethlystilboestrol. We herein report a case of acquired uterine AVM located on the right lateral wall after intrauterine instrumentation for laparoscopic left salpingectomy due to left tubal pregnancy. The patient was successfully treated with embolization. PMID:25264537

Chang, Kylie Hae-Jin; Park, Jong-Kyu; Park, Sung-Ho; Kim, Hong-Bae

2014-01-01

392

Myocardial infarction due to lightning strike.  

PubMed

Cardiac events due to lightning strike and their severity vary according to the strength of the electric current and the duration of exposure. The electrophysiological effects of lightning on the heart can result in ventricular fibrillation, asystole, QT prolongation, supraventricular tachycardia, and non-specific ST-T wave changes. In this report, a case of a patient who suffered myocardial infarction due to lightning strike is presented, which is a rare complication. PMID:24601203

Karadas, Sevdegul; Vuruskan, Ertan; Dursun, Recep; Sincer, Isa; Gonullu, Hayriye; Akkaya, Emre

2013-09-01

393

Massive hemothorax due to intrathoracic extramedullary hematopoiesis in a patient with beta thalassemia hemoglobin E disease.  

PubMed

Case report of a 28-year-old man with beta thalassemia/hemoglobin E disease who developed a massive hemothorax due to bleeding from multiple large intrathoracic, paraspinal hematopoietic masses. Initially, a thoracotomy was required for the control of bleeding. Postoperatively, the patient received 2,000 ml of packed red cells but he continued bleeding after the blood chemistries and coagulopathy specimen were corrected. The decision was made to return to the operating room for a thoracotomy to control the bleeding. However, before re-operating, the patient underwent a collapse and failed resuscitation. This complication has never been previously reported in Thailand. PMID:24319860

Tantraworasin, Apichat; Saeteng, Somcharoen

2013-07-01

394

Prostate angiosarcoma: is there any association with previous radiation therapy?  

PubMed Central

For the current review a literature search was carried out using Pubmed, EmBase, and Cochrane databases. All cases of prostate angioscaroma reported to date and observational studies evaluating the radiation associated cancer occurrence were reviewed. Despite the rarity, prostate angiosarcomas display remarkable clinical and pathological heterogeneity, and a treatment challenge. We found the association of prostate angiosarcoma with radiation therapy to be weak based upon the results from observational studies and case reports. Although radiation exposure has been suggested etiology of prostate angiosarcomas, assumption of such association is not supported by the current literature. PMID:22583810

Khaliq, Waseem; Meyer, Christian F.; Uzoaru, Ikechukwu; Wolf, Richard M.; Antonarakis, Emmanuel S.

2013-01-01

395

Fewer essential genes in mycoplasmas than previous studies suggest.  

PubMed

Here, we describe mutants of Mycoplasma pulmonis that were obtained using a minitransposon, Tn4001TF1, which actively transposes but is then unable to undergo subsequent excision events. Using Tn4001TF1, we disrupted 39 genes previously thought to be essential for growth. Thus, the number of genes required for growth has been overestimated. This study also revealed evidence of gene duplications in M. pulmonis and identified chromosome segregation proteins that are dispensable in mycoplasmas but essential in Bacillus subtilis. PMID:20722737

Dybvig, Kevin; Lao, Ping; Jordan, David S; Simmons, Warren L

2010-10-01

396

[Shoulder arthritis due to Haemophilus aphrophilus].  

PubMed

We report a case of shoulder arthritis due to Haemophilus aphrophilus. The patient, a 56 year-old woman, was immunocompetent. She presented with a septic arthritis of the left shoulder without portal of entry. A synovial fluid sample was cultured and positive for a gram-negative bacillus after 8 days. It was identified as Haemophilus aphrophilus, in the HACCEK group, by PCR ARN 16S. We did not find any associated endocarditis. The patient recovered. As far as we know, this is only the 5th reported case of arthritis due to this microorganism. PMID:15982845

Bouldouyre, M-A; Stawiarski, N; Michon, M; Nguyen Van, J-C; Ben-Ali, A; Rajzbaum, G; Goldstein, F-W

2005-06-01

397

Splenic Infarct Due to Scrub Typhus  

PubMed Central

Scrub typhus is a mite borne infectious disease that has the potential to involve multiple organs and can be fatal. Involvement of the abdomen in the form of hepatitis, gastric ulcerations and pancreatitis are well-documented, the pathology being disseminated vasculitis. However involvement of the spleen in scrub typhus is extremely rare and is reported only in a few autopsy studies. We report the case of a 50-year-old lady who presented with fever and left upper quadrant abdominal pain due to a splenic infarct due to scrub typhus. PMID:24926171

Raj, Selvin Sundar; Krishnamoorthy, Adhiti; Jagannati, Manjeera; Abhilash, Kundavaram PP

2014-01-01

398

Splenic infarct due to scrub typhus.  

PubMed

Scrub typhus is a mite borne infectious disease that has the potential to involve multiple organs and can be fatal. Involvement of the abdomen in the form of hepatitis, gastric ulcerations and pancreatitis are well-documented, the pathology being disseminated vasculitis. However involvement of the spleen in scrub typhus is extremely rare and is reported only in a few autopsy studies. We report the case of a 50-year-old lady who presented with fever and left upper quadrant abdominal pain due to a splenic infarct due to scrub typhus. PMID:24926171

Raj, Selvin Sundar; Krishnamoorthy, Adhiti; Jagannati, Manjeera; Abhilash, Kundavaram Pp

2014-04-01

399

Reconsolidation May Incorporate State-Dependency into Previously Consolidated Memories  

ERIC Educational Resources Information Center

Some memories enter into a labile state after retrieval, requiring reconsolidation in order to persist. One functional role of memory reconsolidation is the updating of existing memories. There are reports suggesting that reconsolidation can be modulated by a particular endogenous process taking place concomitantly to its natural course, such as…

Sierra, Rodrigo O.; Cassini, Lindsey F.; Santana, Fabiana; Crestani, Ana P.; Duran, Johanna M.; Haubrich, Josue; de Oliveira Alvares, Lucas; Quillfeldt, Jorge A.

2013-01-01

400

Relationship of deer and moose populations to previous winters' snow  

USGS Publications Warehouse

(1) Linear regression was used to relate snow accumulation during single and consecutive winters with white-tailed deer (Odocoileus virginianus) fawn:doe ratios, mosse (Alces alces) twinning rates and calf:cow ratios, and annual changes in deer and moose populations. Significant relationships were found between snow accumulation during individual winters and these dependent variables during the following year. However, the strongest relationships were between the dependent variables and the sums of the snow accumulations over the previous three winters. The percentage of the variability explained was 36 to 51. (2) Significant relationships were also found between winter vulnerability of moose calves and the sum of the snow accumulations in the current, and up to seven previous, winters, with about 49% of the variability explained. (3) No relationship was found between wolf numbers and the above dependent variables. (4) These relationships imply that winter influences on maternal nutrition can accumulate for several years and that this cumulative effect strongly determines fecundity and/or calf and fawn survivability. Although wolf (Canis lupus L.) predation is the main direct mortality agent on fawns and calves, wolf density itself appears to be secondary to winter weather in influencing the deer and moose populations.

Mech, L.D.; McRoberts, R.E.; Peterson, R.O.; Page, R.E.

1987-01-01

401

A previously unidentified host protein protects retroviral DNA from autointegration  

PubMed Central

Integration of a DNA copy of the viral genome into a host chromosome is an essential step in the retrovirus life cycle. The machinery that carries out the integration reaction is a nucleoprotein complex derived from the core of the infecting virion. To successfully integrate into host DNA, the viral DNA within this complex must avoid self-destructive integration into itself, a reaction termed autointegration. We have previously shown [Lee, M. S. and Craigie, R. (1994) Proc. Natl. Acad. Sci. USA 91, 9823–9827] that viral nucleoprotein complexes isolated from Moloney murine leukemia virus-infected cells exhibit a barrier to autointegration. This autointegration barrier could be destroyed by stripping factors from the complexes and subsequently restored by incubation with a host cell extract, but not by incubation with an extract of disrupted virions. We have now used this autointegration barrier reconstitution assay to purify the host factor from uninfected NIH 3T3 fibroblasts. It is a single polypeptide of 89 aa that does not match any previously identified protein. The identity of the protein was confirmed by expressing it in Escherichia coli and demonstrating the activity of the heterologously expressed protein in the reconstitution assay. PMID:9465049

Lee, Myung Soo; Craigie, Robert

1998-01-01

402

Septic arthritis due to Cellulosimicrobium cellulans.  

PubMed

Cellulosimicrobium cellulans has been reported as a rare cause of human pathogenesis. Infections mainly occur in immunocompromised patients and very often are associated with a foreign body. We report the first case of septic arthritis caused by C. cellulans in an immunocompetent patient. Our patient suffered a penetrating palm tree thorn injury to his left knee 8 weeks before admission. Although no foreign objects were found, they were suspected because previous reports suggest a frequent association with this microorganism, and open debridament was performed. Removal of foreign bodies related to this organism must be considered a high-priority treatment in these patients to achieve a complete recovery. PMID:21998421

Magro-Checa, César; Chaves-Chaparro, Lara; Parra-Ruiz, Jorge; Peña-Monje, Alejandro; Rosales-Alexander, José Luis; Salvatierra, Juan; Raya, Enrique

2011-12-01

403

Septic Arthritis Due to Cellulosimicrobium cellulans?  

PubMed Central

Cellulosimicrobium cellulans has been reported as a rare cause of human pathogenesis. Infections mainly occur in immunocompromised patients and very often are associated with a foreign body. We report the first case of septic arthritis caused by C. cellulans in an immunocompetent patient. Our patient suffered a penetrating palm tree thorn injury to his left knee 8 weeks before admission. Although no foreign objects were found, they were suspected because previous reports suggest a frequent association with this microorganism, and open debridament was performed. Removal of foreign bodies related to this organism must be considered a high-priority treatment in these patients to achieve a complete recovery. PMID:21998421

Magro-Checa, César; Chaves-Chaparro, Lara; Parra-Ruiz, Jorge; Peña-Monje, Alejandro; Rosales-Alexander, José Luis; Salvatierra, Juan; Raya, Enrique

2011-01-01

404

Cutaneous fistula of liver echinococcal cyst previously misdiagnosed as fistulizated rib osteomyelitis  

PubMed Central

External fistulization or subcutaneous rupture of liver echinococcal cyst (EC) is found occasionally with total of 15 cases reported in the literature. We report a case of 60-year-old female previously misdiagnosed as fistulizated osteomyelitis of the 11th rib. At computed tomography scan, non-vital EC was noted in the third liver segment. Under suspicion of external fistulization of perforated EC the patient underwent one-stage operation-pericystectomy and complete fistula excision. A retrospective analysis of the reported cases in the literature was performed with special references to classifying this rare entity. The main purpose of this report is to highlight the possibility of such a diagnosis when cutaneous fistula occurs in a same anatomic area with hydatid EC, even that cyst is proven to be calcified. We emphasize the role of a swift and radical surgical procedure including complete fistula excision to prevent secondary dissemination and post-operative complications. PMID:24471005

Kjossev, Kirien T; Teodosiev, Ivan L

2013-01-01

405

Fatal case of necrotizing fasciitis due to Myroides odoratus.  

PubMed

Myroides sp., previously known as Flavobacterium odoratum, is a relatively unknown organism with unclear human pathogenicity. While Myroides sp. has been implicated in human infections, many reports have described the organism as a relatively avirulent opportunistic pathogen. We present an unusual case of rapidly fatal necrotizing fasciitis and septic shock due to Myroides odoratus. Our case demonstrates the pathogenicity of Myroides, and highlights potential risk factors for infection including underlying liver disease and open wounds. The recognition of Myroides is of particular importance given its resistance to multiple antibiotics. We review the literature on Myroides sp. skin and soft tissue infections, including necrotizing forms, and discuss the clinical presentation and management of this potentially emerging pathogen. PMID:24806817

Crum-Cianflone, N F; Matson, R W; Ballon-Landa, G

2014-10-01

406

Squamous carcinoma of the penis and previous recurrent balanitis: a case report.  

PubMed Central

A 33 year old uncircumcised Caucasian male who had a 7 year history of intermittent erosive balanitis and herpes, presented with an 18 month history of progressively worsening penile ulceration not responding to the usual medication. Biopsy of the glans penis carried out in view of the long standing ulceration showed a sqamous cell carcinoma of the penis. As there was no response to radiotherapy, partial penectomy was carried out. The importance of early biopsy is emphasised when ulcerative lesions of the penis do not respond adequately to medical therapy. Different treatment modalities available are reviewed. Images PMID:2032711

Fernando, J J; Wanas, T M

1991-01-01

407

[Giant calcified meningioma after radiation therapy for previous ependymoma: a case report].  

PubMed

We presented a case of secondary giant meningioma with dense calcification (brain stone) after radiation therapy for primary ependymoma removed 25 years before. A 31-year-old man was referred to our hospital because of generalized convulsion. He had received extirpation of an ependymoma in the left frontoparietal region and postoperative radiation therapy 25 years before. Skull X-ray and CT revealed a giant brain stone in the left parietal region. It was totally removed en bloc. Photomicrograph of the specimen showed proliferation of arachnoid cell-like tumor cells in narrow spaces surrounded by marked calcified lesions which showed partial ossification. The etiology and therapy of this tumor were discussed. PMID:8377902

Zenke, K; Fukumoto, S; Ohta, S; Sakaki, S; Matsui, S

1993-09-01

408

College students with previous exposure to crime report more PTSD after 9-11-2001.  

PubMed

A sample of 415 university students (52 Crime Victims, 363 Nonvictims) who experienced indirectly the 9/11/01 disaster through media exposure, were administered the Davidson Trauma Scale. Crime victims had significantly more PTSD symptoms related to 9/11 exposure. PMID:17153829

Saylor, Conway; DeRoma, Virginia; Swickert, Rhonda

2006-10-01

409

Therapeutic Foster Care--Update and Brief Summary of Previous Report  

E-print Network

for no more than one or two TFC children and receive ongoing support and training, (6) caseworkers’ caseloads are limited to 10-15 children, and (7) TFC families are reimbursed at higher rates than general foster care. Therapeutic Foster Care Update... biological families in the TFC process (15) provides assistance for foster families to consistently engage with biological families; Therapeutic Foster Care Update 6 (16) provides for aftercare for TFC families and biological families; (17) allows...

Walter, Uta M.; Petr, Chris

2005-10-01

410

Detecting Area Sensitivity: A Comment on Previous Studies  

Microsoft Academic Search

ABSTRACT.—Several studies have reported,that some,grassland birds are area sensitive; they exhibit a nonrandom avoidance of small fields. The methods used to test for area sensitivity, however, differed among studies. Some investigators sampled fields with sampling effort pro- portional to field size, whereas others used equal sampling effort in all fields. We created a simulation model,with the same,number,of fields and field

DAVID JOSEPH HORN; ROBERT J. FLETCHER; ROLF R. KOFORD

2000-01-01

411

The Course of Due Process.  

ERIC Educational Resources Information Center

Discussion of due process rights for children with disabilities considers common issues leading to due process requests, due process procedures, hearing officers, procedural violations, effects of due process meetings, and areas for improvement (i.e., accountability, paperwork). Tables list categories of procedural violations with examples and…

Getty, Laura A.; Summy, Sarah E.

2004-01-01

412

A previously undescribed potyvirus isolated and characterized from arborescent Brugmansia.  

PubMed

A suspected virus disease was identified from an arborescent Brugmansia x candida Pers. (syn. Datura candida Pers.) tree. The causal agent was aphid transmissible at low rates. Viral particles were purified from infected tobacco tissue, analyzed, and purified virions were inoculated into healthy tobacco plants to recreate the symptoms. The virions had a mean length of 720-729 nm, and infected cells contained inclusion bodies typical of potyvirus infections. Analysis of infected tissues and purified virions with a panel of potyvirus-specific antibodies confirmed identification as a potyvirus. Viral host range, dilution end point, thermal tolerance and aphid transmission characteristics were examined. The viral genome (9761 nt) is typical of potyviruses, with the closest related potyvirus being pepper mottle virus, at 72 % nt sequence identity. Based on conventions for naming novel potyviruses, the virus was determined to be a member of a previously undescribed species, tentatively named "Brugmansia mosaic virus" (BruMV). PMID:23381392

Damsteegt, Vernon D; Stone, Andrew L; Smith, Oney P; McDaniel, Lawrence; Sherman, Diana J; Dardick, Chris; Hammond, John; Jordan, Ramon; Schneider, William L

2013-06-01

413

Spin exercise improves semantic fluency in previously sedentary older adults.  

PubMed

Studies suggest improvements of neurocognitive function among older adults who undergo aerobic exercise training. This study sought to examine the impact of an aerobic exercise intervention on verbal fluency in sedentary older adults. Twenty community-dwelling older adults were recruited and enrolled in either a spin exercise group or a control condition. Participants were evaluated with an estimated V02max test and on measures of letter, category, and switching verbal fluency both before and after a 12-week intervention period. Spin exercise resulted in a significant improvement in category (semantic) verbal fluency when compared with the control group (15% vs. 2% increase, respectively; P = .001). Spin exercise also resulted in a significant improvement in estimated V02max (P = .005). Also important, the spin exercise group demonstrated a high level of adherence (mean adherence = 82.5%). Spin exercise can be an effective mode of aerobic exercise to improve semantic fluency in previously sedentary older adults. PMID:24425525

Nocera, Joe R; McGregor, Keith M; Hass, Chris J; Crosson, Bruce

2015-01-01

414

Reutilization of previously hybridized slides for fluorescence in situ hybridization  

SciTech Connect

Application of fluorescence in situ hybridization (FISH) to clinical material is sometimes limited by sample size. In addition, heterogeneity among slides prepared from a single sample may lead to variation in FISH analyses. Reutilization of material for repeated FISH analyses would help to alleviate these problems. We have developed a simple procedure for repeated FISH analyses with directly conjugated probes. Previously hybridized probes are removed by incubation in denaturing solution, and slides can then be rehybridized without residual signals remaining. Several cycles of this procedure allow a full complement of chromosomal loci to be analyzed on the same population of cells. Advantages of this protocol include gaining more cytogenetic information from small samples and eliminating the problem of intratumorvariability. 5 refs., 4 figs.

Epstein, L.; DeVries, S.; Waldman, F.M. [Univ. of California, San Francisco, CA (United States)

1995-12-01

415

Importance of neurological evaluation before reverse shoulder arthroplasty in patients with previous poliomyelitis.  

PubMed

We present a case report of a patient, affected by post-polio syndrome and cuff tear arthropathy of his right shoulder, who underwent reverse shoulder arthroplasty. A previous radial deficiency was unmasked in the post-operative follow-up, with passive elbow bending when the forearm was put in an antigravitational position. A precise preoperative neurological evaluation is mandatory in shoulder replacement in order to estimate the functional outcome after surgery. PMID:19367520

Castoldi, Filippo; Lollino, Nicola; Caranzano, Francesco; Assom, Marco

2009-06-01

416

A Group of Previously Not Recognized Cytogenetic Abnormalities in Myeloid Hematological Malignancies  

Microsoft Academic Search

We have identified a group of previously not reported chromosome abnormalities related to myeloid hematological malignancies. Cases 1 and 2 were observed to have an additional i(4)(p10) as the sole anomaly with similar clinical features of myeloid disorders; that is, acute nonlymphocytic leukemia (ANLL-M2) and myelodysplastic syndrome (MDS)-refractory anemia with an excess of blasts in transformation, respectively. Fluorescence in situ

Zhong Chen; Kathy Richkind; Synthia Roherty; John Velasco; Christian Lytle; Arthur R Brothman; Avery A Sandberg

1999-01-01

417

Twelve previously unknown phage genera are ubiquitous in global oceans  

SciTech Connect

Viruses are fundamental to ecosystems ranging from oceans to humans, yet our ability to study them is bottlenecked by the lack of ecologically relevant isolates, resulting in unknowns dominating culture-independent surveys. Here we present genomes from 31 phages infecting multiple strains of the aquatic bacterium Cellulophaga baltica (Bacteroidetes) to provide data for an underrepresented and environmentally abundant bacterial lineage. Comparative genomics delineated 12 phage groups that (i) each represent a new genus, and (ii) represent one novel and four wellknown viral families. This diversity contrasts the few well-studied marine phage systems, but parallels the diversity of phages infecting human-associated bacteria. Although all 12 Cellulophaga phages represent new genera, the podoviruses and icosahedral, nontailed ssDNA phages were exceptional, with genomes up to twice as large as those previously observed for each phage type. Structural novelty was also substantial, requiring experimental phage proteomics to identify 83% of the structural proteins. The presence of uncommon nucleotide metabolism genes in four genera likely underscores the importance of scavenging nutrient-rich molecules as previously seen for phages in marine environments. Metagenomic recruitment analyses suggest that these particular Cellulophaga phages are rare and may represent a first glimpse into the phage side of the rare biosphere. However, these analyses also revealed that these phage genera are widespread, occurring in 94% of 137 investigated metagenomes. Together, this diverse and novel collection of phages identifies a small but ubiquitous fraction of unknown marine viral diversity and provides numerous environmentally relevant phage host systems for experimental hypothesis testing.

Holmfeldt, Karin [University of Arizona] [University of Arizona; Solonenko, Natalie [University of Arizona] [University of Arizona; Shah, Manesh B [ORNL] [ORNL; Corrier, Kristen L [ORNL] [ORNL; Riemann, Lasse [University of Copenhagen] [University of Copenhagen; Verberkmoes, Nathan C [ORNL] [ORNL; Sullivan, Matthew B [University of Arizona] [University of Arizona

2013-01-01

418

Underground and Previously Undiscovered Rivers in the Mississippi Delta  

NASA Astrophysics Data System (ADS)

In this study we show that there are large, and previously undiscovered, groundwater pathways by which water from the Mississippi River is transported to the wetlands and estuaries of the Mississippi River Delta. Results from multiple methodologies suggest that the total flux of groundwater to the coastal zone in the Mississippi River Delta averages 1,000 m3 s-1, and can reach 5,000 m3 s-1 at high flow. We suggest that flow preferentially occurs through paleo-crevasse channels, relict bayous, and other buried deposits of permeable and coarse grained material. These conduits were formed during the present and previous stages of the delta cycle, which occurred in historical (102 y) and late Holocene(103 y) times, respectively. Flow is driven by the hydrological head difference between the river and the estuary, which is seasonally variable in magnitudeand can reach 5-8 m during peak river floods. This talk will present data from hydrological budgets that show a missing fraction in the Mississippi River water budget, and a missing source of fresh water to a large estuary. We will show that water levels in wells in New Orleans fluctuate with the stage of the Mississippi River. Data of Rn concentration indicate advective submarine groundwater flow, whereas Ba concentrations suggest geochemical leachates are entering the estuary. Furthermore, seismic data indicate the prevalence of paleochannels and other buried features that could carry flow. Given the importance of deltas to global geochemical budgets, we suggest that these results may be generalizable: submarine groundwater discharge in deltas may prove to be an important but understudied pathway by which dissolved materials are transported from the continents to the ocean.

Kolker, A.; Breaux, A.; Coleman, D.; Inniss, L. V.; Telfeyan, K.; Kim, J.; Schneider, A.; Allison, M. A.; Cable, J. E.; Johannesson, K. H.

2013-12-01

419

Recurrent Port Infection Due to Chryseobacterium Indologenes  

PubMed Central

Infections due to Chryseobacterium indologenes (C. indologenes) are rare and generally associated with immunosupression and indwelling catheters. We report a recurrent port infection caused by C. indologenes. In the first bacteremia episode we did not remove the port and only applied antibiotherapy. However, the patient presented with bacteremia with the same bacteria and successfully treated with antibiotherapy and removal of the port.

Mutcali, Sibel Islak; Yemisen, Mucahit; Soylu, Hikmet; Balkan, Ilker Inanc; Mete, Bilgul; Saltoglu, Nese

2013-01-01

420

The accuracy of clinical malaria case reporting at primary health care facilities in Honiara, Solomon Islands  

Microsoft Academic Search

BACKGROUND: The accuracy of malaria case reporting is challenging due to restricted human and material resources in many countries. The reporting often depends on the clinical diagnosis because of the scarcity of microscopic examinations. Particularly, clinical malaria case reporting by primary health care facilities (local clinics), which constitutes the baseline data of surveillance, has never previously been sufficiently evaluated. In

Ayano Kunimitsu

2009-01-01

421

Intestinal Obstruction due to Bilateral Strangulated Femoral Hernias  

PubMed Central

Introduction. Femoral hernias are at high risk of strangulation due to the narrow femoral canal and femoral ring. This can lead to symptoms of obstruction or strangulation requiring emergency surgery and possible bowel resection. To our knowledge, there is only one previous published report of bilateral strangulated femoral hernia. We present our case of this phenomenon. Case Report. An 86-year-old woman presented with symptoms of small bowel obstruction. Examination revealed two tender lumps in the area of the femoral triangle. CT scan revealed bilateral femoral hernias. Both hernias were repaired and a small bowel resection on the right side was performed with side to side anastomosis. She made an uneventful recovery. Conclusion. Bilateral femoral hernias are a rare occurrence with only one reported case of bilateral strangulation. Our case highlights the importance of meticulous history taking and clinical examination as any delay in diagnosis will increase the risk of mortality and morbidity for the patient. Hernias should always be considered as a cause if one presents with symptoms of abdominal pain or obstruction. PMID:25057426

Nikolopoulos, Ioannis; Oderuth, Eshan; Ntakomyti, Eleni; Kald, Bengt

2014-01-01

422

Local cytokine transcription in naïve and previously infected sheep and lambs following challenge with Teladorsagia circumcincta  

PubMed Central

Background The abomasal helminth Teladorsagia circumcincta is one of the most economically important parasites affecting sheep in temperate regions. Infection is particularly detrimental to lambs, in which it can cause pronounced morbidity and severe production losses. Due to the spreading resistance of this parasite to all classes of anthelmintic drugs, teladorsagiosis is having an increasingly severe impact on the sheep industry with significant implications for sheep welfare. Protective immunity develops slowly, wanes rapidly and does not appear to be as effective in young lambs. To investigate the development of immunity to T. circumcincta in sheep and lambs, we used cytokine transcript profiling to examine differences in the abomasal mucosa and gastric lymph node of naïve and previously infected sheep and lambs following challenge. Results The results of these experiments demonstrated that the abomasal mucosa is a major source of cytokines during abomasal helminth infection. A local Th2-type cytokine response was observed in the abomasal mucosa and gastric lymph node of the previously infected sheep and lambs when compared with those of the naïve during the early stages of infection. In contrast, a pro-inflammatory component more was evident in the abomasal mucosa and gastric lymph node of the naïve sheep when compared with those of the previously infected, which was not observed in the lambs. Conclusions The greater levels of Th2-type cytokine transcripts in both the abomasum and gastric lymph node of the previously infected compared with naïve sheep and lambs emphasises the importance of these mechanisms in the immune response to T. circumcincta infection. Younger lambs appear to be able to generate similar Th2-type responses in the abomasum suggesting that the increased morbidity and apparent lack of resistance in younger lambs following continuous or repeated exposure to T. circumcincta is unlikely to be due to a lack of appropriate Th2-type cytokine production. PMID:24712712

2014-01-01

423

Total knee arthroplasty in patients with a previous patellectomy.  

PubMed

Post-patellectomy patients represent a specific subgroup of patients that may develop arthritis and persistent knee pain and potentially require treatment with total knee arthroplasty. This article reviews the treatment and functional outcomes following total knee arthroplasty in patients with prior patellectomy. A case report is presented as an example of the clinical management of a post-patellectomy patient with significant knee pain and disability treated with total knee arthroplasty. Emphasis will be placed in decision- making, specifically with the use of a posterior stabilized implant. In addition, postoperative strengthening of the quadriceps is essential to compensate for the lack of the patella and increase the success of total knee arthroplasty in this subgroup of patients. PMID:24151951

Maslow, Jed; Zuckerman, Joseph D; Immerman, Igor

2013-01-01

424

Multifunctional Core–Shell Nanoparticles: Discovery of Previously Invisible Biomarkers  

PubMed Central

Many low-abundance biomarkers for early detection of cancer and other diseases are invisible to mass spectrometry because they exist in body fluids in very low concentrations, are masked by high-abundance proteins such as albumin and immunoglobulins, and are very labile. To overcome these barriers, we created porous, buoyant, core–shell hydrogel nanoparticles containing novel high affinity reactive chemical baits for protein and peptide harvesting, concentration, and preservation in body fluids. Poly(N-isopropylacrylamide-co-acrylic acid) nanoparticles were functionalized with amino-containing dyes via zero-length cross-linking amidation reactions. Nanoparticles functionalized in the core with 17 different (12 chemically novel) molecular baits showed preferential high affinities (KD < 10–11 M) for specific low-abundance protein analytes. A poly(N-isopropylacrylamide-co-vinylsulfonic acid) shell was added to the core particles. This shell chemistry selectively prevented unwanted entry of all size peptides derived from albumin without hindering the penetration of non-albumin small proteins and peptides. Proteins and peptides entered the core to be captured with high affinity by baits immobilized in the core. Nanoparticles effectively protected interleukin-6 from enzymatic degradation in sweat and increased the effective detection sensitivity of human growth hormone in human urine using multiple reaction monitoring analysis. Used in whole blood as a one-step, in-solution preprocessing step, the nanoparticles greatly enriched the concentration of low-molecular weight proteins and peptides while excluding albumin and other proteins above 30 kDa; this achieved a 10,000-fold effective amplification of the analyte concentration, enabling mass spectrometry (MS) discovery of candidate biomarkers that were previously undetectable. PMID:21999289

2011-01-01

425

Ovarian remnant syndrome: a case report.  

PubMed

A case is reported of ureteral obstruction due to retained corpus luteum. The patient had previously undergone a hysterectomy and salpingo-ovariectomy with incomplete removal of ovarian tissue on both sides. The ureteral obstruction was treated by the excision of the mass and the reimplantation of the obstructed ureter into the bladder hitched to psoas muscle. PMID:2141720

Visentini, E; Bondavalli, C; Pegoraro, C; Schiavon, L; Dall'Oglio, B; Parma, A

1990-03-01

426

Summary of Previous Chamber or Controlled Anthrax Studies and Recommendations for Possible Additional Studies  

SciTech Connect

This report and an associated Excel file(a) summarizes the investigations and results of previous chamber and controlled studies(b) to characterize the performance of methods for collecting, storing and/or transporting, extracting, and analyzing samples from surfaces contaminated by Bacillus anthracis (BA) or related simulants. This report and the Excel are the joint work of the Pacific Northwest National Laboratory (PNNL) and the National Institute of Standards and Technology (NIST) for the Department of Homeland Security, Science and Technology Directorate. The report was originally released as PNNL-SA-69338, Rev. 0 in November 2009 with limited distribution, but was subsequently cleared for release with unlimited distribution in this Rev. 1. Only minor changes were made to Rev. 0 to yield Rev. 1. A more substantial update (including summarizing data from other studies and more condensed summary tables of data) is underway

Piepel, Gregory F.; Amidan, Brett G.; Morrow, Jayne B.

2010-12-29

427

Total Knee Arthroplasty in a Patient with an Ankylosing Knee after Previous Patellectomy  

PubMed Central

Patellectomized patients may have less satisfactory clinical outcomes following total knee arthroplasty (TKA) due to a decreased extensor mechanism efficiency and potential instability. Furthermore, the existing literature does not provide concrete guidance on the expected results of TKA or the type of implant that should be used in patellectomized patients. We present a case of a patient with an ankylosing knee who had undergone patellectomy due to gunshot injury 45 years ago and was treated with primary TKA using a posterior stabilized prosthesis at our institution. TKA using this prosthesis in the ankylosed knee with a previous history of patellectomy yielded good results in terms of postoperative clinical scores, range of motion and joint stability. PMID:25229049

Rhee, Seung Joon; Park, Shi Hwan; Hong, Sung Min

2014-01-01

428

Ibrutinib versus Ofatumumab in Previously Treated Chronic Lymphoid Leukemia  

PubMed Central

Background In patients with chronic lymphoid leukemia (CLL) or small lymphocytic lymphoma (SLL), a short duration of response to therapy or adverse cytogenetic abnormalities are associated with a poor outcome. We evaluated the efficacy of ibrutinib, a covalent inhibitor of Bruton’s tyrosine kinase, in patients at risk for a poor outcome. Methods In this multicenter, open-label, phase 3 study, we randomly assigned 391 patients with relapsed or refractory CLL or SLL to receive daily ibrutinib or the anti-CD20 antibody ofatumumab. The primary end point was the duration of progression-free survival, with the duration of overall survival and the overall response rate as secondary end points. Results At a median follow-up of 9.4 months, ibrutinib significantly improved progression-free survival; the median duration was not reached in the ibrutinib group (with a rate of progression-free survival of 88% at 6 months), as compared with a median of 8.1 months in the ofatumumab group (hazard ratio for progression or death in the ibrutinib group, 0.22; P<0.001). Ibrutinib also significantly improved overall survival (hazard ratio for death, 0.43; P = 0.005). At 12 months, the overall survival rate was 90% in the ibrutinib group and 81% in the ofatumumab group. The overall response rate was significantly higher in the ibrutinib group than in the ofatumumab group (42.6% vs. 4.1%, P<0.001). An additional 20% of ibrutinib-treated patients had a partial response with lymphocytosis. Similar effects were observed regardless of whether patients had a chromosome 17p13.1 deletion or resistance to purine analogues. The most frequent nonhematologic adverse events were diarrhea, fatigue, pyrexia, and nausea in the ibrutinib group and fatigue, infusion-related reactions, and cough in the ofatumumab group. Conclusions Ibrutinib, as compared with ofatumumab, significantly improved progression-free survival, overall survival, and response rate among patients with previously treated CLL or SLL. (Funded by Pharmacyclics and Janssen; RESONATE ClinicalTrials.gov number, NCT01578707.) PMID:24881631

Byrd, J.C.; Brown, J.R.; O’Brien, S.; Barrientos, J.C.; Kay, N.E.; Reddy, N.M.; Coutre, S.; Tam, C.S.; Mulligan, S.P.; Jaeger, U.; Devereux, S.; Barr, P.M.; Furman, R.R.; Kipps, T.J.; Cymbalista, F.; Pocock, C.; Thornton, P.; Caligaris-Cappio, F.; Robak, T.; Delgado, J.; Schuster, S.J.; Montillo, M.; Schuh, A.; de Vos, S.; Gill, D.; Bloor, A.; Dearden, C.; Moreno, C.; Jones, J.J.; Chu, A.D.; Fardis, M.; McGreivy, J.; Clow, F.; James, D.F.; Hillmen, P.

2014-01-01

429

PREVIOUS PHYSICAL ACTIVITY AND BODY BALANCE IN ELDERLY PEOPLE  

PubMed Central

The purpose of the research was to evaluate the efficiency of body balance regulation in the elderly and verify whether physical activity in adolescence could influence later physical efficiency. Research was carried out on 62 persons aged between 65 and 96 years of age. Fifty people declared that they undertook physical activity in adolescence, while 12 reported no activity. Stabilographic examinations were performed during trials with open and closed eyes on a horizontally situated platform tilted forward and backward. The centre-of-pressure (COP) path length, sway range area and centre-of-pressure velocity (COP velocity) were assessed. The safety margin when a person leans forward and backward was evaluated as well. On a horizontally situated platform, exclusion of visual control in most of the examined participants resulted in a significant increase in values of examined parameters. Tilting the platform caused in both groups an increase in values of all the parameters. These changes were more visible when a trial with eyes closed was performed and the group of active people obtained better results. These people were also able to use the support area more effectively when changing the position of the body. It was found that body balance disorder affects more often elderly people who were less active in adolescence and that with age visual balance control dominates the proprioceptive one. This means that physical activity directed towards, among other things, forming and improving the body balance regulation system is needed at an early age. PMID:24795500

Nowotny-Czupryna, O.; Czupryna, K.; Nowotny, J.

2013-01-01

430

Using previous public testimony to prepare risk messages  

SciTech Connect

People need a sense of control over their own lives, but they sometimes feel that they do not have that control when faced with a risk such as that posed by a nuclear power reactor or an incinerator for radioactive waste. Agencies communicating the risk must understand the fears of stakeholders (the people who share in the risk) and try to address those fears. The Emergency Response and Community Right to Know Act, Title 3 of the Superfund Amendments and Reauthorization Act (SARA), is a broad risk communication statute that ensures that the information is available through statutes, public hearings, and the media. To arrive at a decision about a risk concerning them and thereby achieve a sense of control, stakeholders must have access to the information about a decision and then must understand it. Their task is seemingly simple: they only have to use their rights under Title 3 to find information on a risk, act on the information, and make an informed choice about the risk. One way that agencies can help the stakeholders maneuver through the maze of regulations governing a risk and communicating the risk itself is through public hearings that actively seek the involvement of the stakeholders. This report suggests items that should be included in the risk message.

Durbin, M.E.

1991-01-01

431

Glenohumeral stability during a hand-positioning task in previously injured shoulders.  

PubMed

This study aimed to compare glenohumeral stability during functional tasks in subjects with previous dislocation injury against non-injured controls. Six subjects with previous injury and six controls were asked to complete hand-positioning tasks against external forces applied in six directions. Arm kinematics, muscle activations and hand forces were measured and used as input to an inverse-dynamic model of the shoulder that optimised muscle forces to solve the load-sharing problem. Glenohumeral stability was calculated using the direction of the joint reaction force vector in the glenoid. The simulations showed that GH stability was significantly lower in the previously injured group compared to the controls, and that the direction of exerted forces had a significant effect on GH stability, with the hand pushing away from the body and medially producing significantly lower stability. GH stability was significantly lower in the previously injured group for all six force directions, even though all participants were back to normal activities and reported no symptoms from their injuries. PMID:23702698

Marchi, James; Blana, Dimitra; Chadwick, Edward K

2014-03-01

432

Three Cases of Previous Smokers with Rheumatoid Arthritis Who Did Not Respond to Tumor Necrosis Factor Inhibitors Were Treated Successfully with an Anti-Interleukin-6 Receptor Antibody  

PubMed Central

We report three cases of previous smokers who did not respond to TNF inhibitors but who responded successfully to an anti-interleukin-6 receptor antibody (tocilizumab (TCZ)). Case 1 is a 63-year-old woman whose smoking index was 200 and had been complaining of polyarthralgia since 1996. She started treatment with etanercept due to high disease activity, but her DAS28-CRP was 4.2. She was therefore switched to TCZ, which dramatically improved her symptoms; her DAS28-CRP had decreased to 2.1. Case 2 is a 64-year-old man whose smoking index was 1600 and had been complaining of polyarthralgia since 2006. Because his DAS28-CRP score increased over time to 5.9, etanercept and adalimumab were added sequentially, but he showed no response over the course of two years. The patient was therefore switched to TCZ, which dramatically improved his symptoms: his DAS28-CRP decreased to 2.7. Case 3 is a 48-year-old woman whose smoking index was 560 and had been complaining of pain in both knee joints since 2001. She was treated with adalimumab due to high disease activity but showed no response over the course of 1.5 years. The patient was therefore switched to TCZ, and her DAS28-CRP decreased to 1.8. An IL-6 blockade might be suitable for treating these 3 cases of previous smokers. PMID:25648415

Iwata, Yasuo

2015-01-01

433

A cough conundrum in a patient with a previous history of BCG immunotherapy for bladder cancer.  

PubMed

We describe a non-smoker who presented with a persistent cough, weight loss and general malaise, and had a medical history of bladder carcinoma that had been successfully treated with intravesical BCG immunotherapy. Radiology revealed hilar lymphadenopathy, a predominantly mid-zone and lower-zone lung parenchymal nodular pattern with a perilymphatic distribution, a few thickened interlobular septae, and small pleural effusions bilaterally. The T-SPOT.TB blood test was negative. Video-assisted thoracoscopic surgery showed multiple pleural nodules, the histopathology of which showed multiple well-defined non-caseating granulomata. The patient was started on antituberculosis medication for presumed BCGosis--a systemic complication of previous BCG immunotherapy--and the patient showed an excellent clinical and radiological response. This case further adds to previous reports and reinforces the recommendation that all patients should be made fully aware of the potential systemic and delayed complications of BCG immunotherapy when they are consented for treatment. PMID:23097577

Mehta, Arpan R; Mehta, Puja R; Mehta, Rajesh L

2012-01-01

434

Previous experience in manned space flight: A survey of human factors lessons learned  

NASA Technical Reports Server (NTRS)

Previous experience in manned space flight programs can be used to compile a data base of human factors lessons learned for the purpose of developing aids in the future design of inhabited spacecraft. The objectives are to gather information available from relevant sources, to develop a taxonomy of human factors data, and to produce a data base that can be used in the future for those people involved in the design of manned spacecraft operations. A study is currently underway at the Johnson Space Center with the objective of compiling, classifying, and summarizing relevant human factors data bearing on the lessons learned from previous manned space flights. The research reported defines sources of data, methods for collection, and proposes a classification for human factors data that may be a model for other human factors disciplines.

Chandlee, George O.; Woolford, Barbara

1993-01-01

435

Replication of genetic linkage by follow-up of previously studied pedigrees  

SciTech Connect

Independent replication of linkage in previously studied pedigrees is desirable when genetic heterogeneity is suspected or when the illness is very rare. When the likelihood of the new data in this type of replication study is computed as conditional on the previously reported linkage results, it can be considered independent. The authors describe a simulation method using the SLINK program in which the initial data are fixed and newly genotyped individuals are simulated under [theta] = .01 and [theta] = .50. These give appropriate lod score criteria for rejection and acceptance of linkage in the follow-up study, which take into account the original marker genotypes in the data. An estimate of the power to detect linkage in the follow-up data is also generated. 13 refs., 1 fig., 1 tab.

Gershon, E.S.; Goldin, L.R. (National Institute of Mental Health, Bethesda, MD (United States))

1994-04-01

436

Streptococcus agalactiae endocarditis presenting as acalculous cholecystitis in a previously well woman  

PubMed Central

This case report describes the unusual presentation of a previously very well woman with Streptococcus agalactiae endocarditis in the emergency department. History, examination and preliminary laboratory and radiological investigations supported a diagnosis of acalculous cholecystitis, for which she was given intravenous broad spectrum antimicrobial therapy. One day following admission, the patient deteriorated and became unresponsive. Subsequent MRI of the brain revealed multiple bihemispheric cerebral emboli and a large, mobile mitral valve thrombus was visualised on her transoesophageal echocardiogram. S agalactiae was cultured from venous blood samples and her antimicrobial cover was adjusted accordingly. Despite her presumed guarded prognosis, this patient made a remarkable recovery. To our knowledge, the association of S agalactiae endocarditis with acalculous cholecystitis has not been previously described. PMID:23405002

Brewer, Linda; Lavan, Amanda Hanora; Cullen, Laura; Duggan, Joseph

2013-01-01

437

Protective effect of previous cardiac operation: survival of contained right ventricular rupture.  

PubMed

Although cardiac contusions are common, cardiac rupture is an uncommon sequela of blunt chest trauma. The mortality rate associated with cardiac rupture is very high, and patients usually do not survive long enough to reach the hospital. We report a 66-year-old man with a history of coronary artery bypass grafting 15 years previously, who was involved in a traffic accident and experienced multiple trauma, including a small contained rupture of the right ventricular outflow tract. He survived, and a false aneurysm developed at the site of the rupture within the next 6 months. The patient then underwent a cardiac operation, and the aneurysm was successfully resected. The intraoperative and postoperative courses were uneventful. In this case, the previous cardiac operation with the resulting pericardial adhesions proved to be lifesaving. PMID:23522211

Wilbring, Manuel; Tugtekin, Sems Malte; Daubner, Dirk; Ouda, Ahmed; Kappert, Utz; Matschke, Klaus

2013-04-01

438

Due Process in the Student-Institutional Relationship.  

ERIC Educational Resources Information Center

Students are making increasingly strong efforts to exercise what they consider to be their rights, and it is becoming ever more crucial to define what these rights are and what the concept of "due process" means. This report explains the meaning of procedural due process: the concept of "dueness" and the student's "right" to due process. In…

Fischer, Thomas C.

439

An Isolated Articular Surface Fracture of the Distal Patella: An Unusual and Previously Unreported Paediatric Injury  

PubMed Central

Paediatric patella fractures are uncommon, accounting for less than 1% of all paediatric fractures. This case report describes a previously undocumented patella fracture in a child, with a clear mechanism of injury. We present a case of a previously healthy 14-year-old boy who fell directly onto his right knee after coming off his pushbike. He sustained an isolated fracture involving the articular surface of the distal part of the patella with minimal displacement. The patient was managed conservatively in a Richard splint for three weeks, followed by a knee brace with gradually increasing degrees of flexion. He was instructed to be nonweight bearing for two weeks and then partial weight bearing for six weeks. At the final followup, after 9 weeks, the patient had full return of function and standard radiographs show the fracture to be healed. This case report has demonstrated how direct compression to the paediatric patella can cause a fracture isolated to its articular surface. It has detailed the natural progression of this injury to radiographic union, using a conservative management strategy. The authors believe that this case report provides an interesting insight into the variation of paediatric patella fractures and their contrasting management strategies. PMID:24383029

Shivji, Faiz S.; Ramoutar, Darryl N.; Hunter, James B.

2013-01-01

440

New study reveals twice as many asteroids as previously believed  

NASA Astrophysics Data System (ADS)

The ISO satellite Credits: ESA ISO An artist's impression of the ISO spacecraft. The ISO Deep Asteroid Search indicates that there are between 1.1 million and 1.9 million 'space rocks' larger than 1 kilometre in diameter in the so-called 'main asteroid belt', about twice as many as previously believed. However, astronomers think it is premature to revise current assessments of the risk of the Earth being hit by an asteroid. Despite being in our own Solar System, asteroids can be more difficult to study than very distant galaxies. With sizes of up to one thousand kilometres in diameter, the brightness of these rocky objects may vary considerably in just a few minutes. They move very quickly with respect to the stars - they have been dubbed 'vermin of the sky' because they often appear as trails on long exposure images. This elusiveness explains why their actual number and size distribution remains uncertain. Most of the almost 40,000 asteroids catalogued so far (1) orbit the Sun forming the 'main asteroid belt', between Mars and Jupiter, too far to pose any threat to Earth. However, space-watchers do keep a closer eye on another category of asteroids, the 'Near Earth Asteroids' or 'NEAs', which are those whose orbits cross, or are likely to cross, that of our planet. The ISO Deep Asteroid Search (IDAS), the first systematic search for these objects performed in infrared light, focused on main belt asteroids. Because it is impossible to simply point the telescope at the whole main belt and count, astronomers choose selected regions of the belt and then use a theoretical model to extrapolate the data to the whole belt. Edward Tedesco (TerraSystems, Inc., New Hampshire, United States) and François-Xavier Desert (Observatoire de Grenoble, France) observed their main belt selected areas in 1996 and 1997 with ESA's ISO. They found that in the middle region of the belt the density of asteroids was 160 asteroids larger than 1 kilometre per square degree - an area of the sky corresponding to that covered by four full moons as seen from Earth. Then, a model developed by Tedesco and the astronomers Alberto Cellino and Vincenzo Zappala (Osservatorio Astronomico di Torino, Italy), allowed them to estimate the whole asteroid population in the main belt: between 1.1 million and 1.9 million asteroids with a diameter larger than 1 kilometre. "If you consider the average value of 1.5 million asteroids, the ISO result is about twice as high as estimated by two other recent studies in visible light," Tedesco says. The study by Durda et al., published in 1998, gave an estimate of about 860 000 asteroids larger than 1 kilometre in the main belt. In 2001, Ivezic et al. obtained an even lower figure of 740 000 asteroids based on preliminary data from the Sloan Digital Sky Survey. Why the discrepancy? The fact that visually dark objects - such as asteroids - are better detected in the infrared might explain the discrepancy between visible and infrared results. For an optical telescope, the brightness of an asteroid depends on the visible light it reflects from the Sun. Observations with infrared telescopes, on the other hand, detect the 'heat' of the asteroid, which does not depend that much on the reflected sunlight, but on the absorbed sunlight. As an example, let’s consider two spheres of the same size, and located close to each other in the asteroid belt, one of which reflects ten times as much of the visible light striking it as the other. As seen by an optical telescope, the sphere which reflects more appears ten times brighter than the other sphere which might be even invisible. However, for ISO both spheres would be visible. Actually, the 'dark' sphere would appear brighter in the infrared because it would have a higher temperature (as it has absorbed more sunlight). Expert’s ‘best estimate’ Tedesco assumes that both visible and infrared searches might have their own biases, which is the reason why the given results have an error margin. Considering both the visible and infrared results, the 'best estimate' would be &qu

2002-05-01

441

Breastfeeding Report Card 2014  

MedlinePLUS

... this page: About CDC.gov . Breastfeeding Share Compartir Breastfeeding Report Card 2014 Background There are many ways ... Report Card, 2014 - [PDF - 1.25 MB] Previous Breastfeeding Report Cards Breastfeeding Report Card 2013 [1.12 ...

442

World Health Report  

MedlinePLUS

... Español RSS Feed Youtube Twitter Facebook Google + iTunes World health report Menu World health report Previous reports Press kit World health report 2013: Research for universal health coverage ...

443

What Influences the Association between Previous and Future Crashes among Cyclists? A Propensity Score Analysis  

PubMed Central

Background It is known that experience of a previous crash is related to incidence of future crashes in a cohort of New Zealand cyclists. This paper investigated if the strength of such association differed by crash involvement propensity and by the need for medical care in the previous crash. Methods The Taupo Bicycle Study involved 2590 adult cyclists recruited in 2006 and followed over a median period of 4.6 years through linkage to four national databases. The crash involvement propensity was estimated using propensity scores based on the participants' demographic, cycling and residential characteristics. Cox regression modelling for repeated events was performed with multivariate and propensity score adjustments. Analyses were then stratified by quintiles of the propensity score. Results A total of 801 (31.0%) participants reported having experienced at least one bicycle crash in the twelve months prior to the baseline survey. They had a higher risk of experiencing crash events during follow-up (hazard ratio (HR): 1.43; 95% CI: 1.28, 1.60) but in the stratified analysis, this association was significant only in the highest two quintiles of the propensity score where the likelihood of having experienced a crash was more than 33%. The association was stronger for previous crashes that had received medical care (HR 1.63; 95% CI: 1.41, 1.88) compared to those that had not (HR 1.30; 95% CI: 1.14, 1.49). Conclusions Previous crash experience increased the risk of future crash involvement in high-risk cyclists and the association was stronger for previous crashes attended medically. What distinguishes the high risk group warrants closer investigation, and the findings indicate also that health service providers could play an important role in prevention of bicycle crash injuries. PMID:24489945

Tin Tin, Sandar; Woodward, Alistair; Ameratunga, Shanthi

2014-01-01

444

Mycotic aneurysm caused by Burkholderia pseudomallei in a previously healthy returning traveller.  

PubMed

Burkholderia pseudomallei is a common cause of serious, difficult to treat infections in South-East Asia and Northern Australia, but is a rare imported pathogen in the USA and Europe. We report a case of a patient with a mycotic aneurysm caused by B. pseudomallei in a previously healthy returning traveller. The patient presented with 4 weeks of abdominal pain and intermittent fever after a brief vacation in Thailand. The aneurysm was excised and replaced by an autologous deep vein graft, and the patient was treated for 6 months with antibiotics adjusted according to postoperative renal impairment. Twenty-four months after surgery the patient is well and without relapse. PMID:25246454

Bodilsen, Jacob; Vammen, Sten; Fuursted, Kurt; Hjort, Ulla

2014-01-01

445

Cono-spondylar dysplasia: clinical, radiographic, and molecular findings of a previously unreported disorder.  

PubMed

We report on a consanguineous Arab family in which three sibs had an unusual skeletal dysplasia characterized by anterior defects of the spine leading to severe lumbar kyphosis and marked brachydactyly with cone epiphyses. The clinical phenotype also included dysmorphic facial features, epilepsy, and developmental delay. This constellation likely represents a previously undescribed skeletal dysplasia, most probably inherited in an autosomal recessive pattern. A homozygosity mapping approach has thus far failed to unearth the responsible gene as the region shared by these three sibs is 27.7 Mb in size and contains over 200 genes with no obvious candidate. PMID:24975242

Ben-Omran, Tawfeg; Lakhani, Shenela; Almureikhi, Mariam; Ali, Rehab; Takahashi, Atsushi; Miyake, Noriko; Matsumoto, Naomichi; Ikegawa, Shiro; Superti-Furga, Andrea; Unger, Sheila

2014-09-01

446

Surgical Site Infection due to a Preauricular Sinus: A Rare Complication after Craniotomy  

PubMed Central

Summary: Wound infection due to a preauricular sinus after craniotomy has not been previously reported. A 71-year-old woman visited our institute with subarachnoid hemorrhage. The aneurysm was surgically clipped with external decompression. Sixteen days after surgery, a focal erythema and discharging were observed at the inferior end of the skin incision. Careful inspection revealed a small pit there, which was diagnosed as a preauricular sinus. After the infection subsided, the sinus was completely excised. Neurosurgeons must be aware of this rare condition and must opt for complete excision to prevent infectious sequelae even if the preauricular sinus is asymptomatic. PMID:25426340

Anda, Takeo; Mori, Hiroshi

2014-01-01

447

Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray data  

PubMed Central

Background Renal cell carcinoma is a common malignancy that often presents as a metastatic-disease for which there are no effective treatments. To gain insights into the mechanism of renal cell carcinogenesis, a number of genome-wide expression profiling studies have been performed. Surprisingly, there is very poor agreement among these studies as to which genes are differentially regulated. To better understand this lack of agreement we profiled renal cell tumor gene expression using genome-wide microarrays (45,000 probe sets) and compare our analysis to previous microarray studies. Methods We hybridized total RNA isolated from renal cell tumors and adjacent normal tissue to Affymetrix U133A and U133B arrays. We removed samples with technical defects and removed probesets that failed to exhibit sequence-specific hybridization in any of the samples. We detected differential gene expression in the resulting dataset with parametric methods and identified keywords that are overrepresented in the differentially expressed genes with the Fisher-exact test. Results We identify 1,234 genes that are more than three-fold changed in renal tumors by t-test, 800 of which have not been previously reported to be altered in renal cell tumors. Of the only 37 genes that have been identified as being differentially expressed in three or more of five previous microarray studies of renal tumor gene expression, our analysis finds 33 of these genes (89%). A key to the sensitivity and power of our analysis is filtering out defective samples and genes that are not reliably detected. Conclusions The widespread use of sample-wise voting schemes for detecting differential expression that do not control for false positives likely account for the poor overlap among previous studies. Among the many genes we identified using parametric methods that were not previously reported as being differentially expressed in renal cell tumors are several oncogenes and tumor suppressor genes that likely play important roles in renal cell carcinogenesis. This highlights the need for rigorous statistical approaches in microarray studies. PMID:14641932

Lenburg, Marc E; Liou, Louis S; Gerry, Norman P; Frampton, Garrett M; Cohen, Herbert T; Christman, Michael F

2003-01-01

448

Albania: World Oil Report 1991  

SciTech Connect

This paper reports that Albanian oil production totaled 14.6 MMbbl in 1990, compared with 15.54 MMbbl in 1989, a decrease of 6%. Due to wastage and insufficient exploration, Albania is unable to make efficient use of its 14.8-MMbbl refining capacity. Albania last year sought help from Western oil companies to explore its underdeveloped oil fields. This is a radical change from the authorities' previous rejection of outside assistance. Ramiz Alia, the president and head of the ruling Albanian Party of Labor, seems to be adopting a more flexible economic policy due to the growing shortages of food, consumer goods and spare parts.

Hovring, M. (MacKay Consultants, Aberdeen (GB))

1991-08-01

449

Re-sentinel node biopsy after previous breast and axillary surgery.  

PubMed

There is no consensus regarding the strategy for managing the regional lymph nodes in patients with local breast cancer recurrence. This paper reviews the updated data on re-sentinel lymph node biopsy (re-SLNB) after previous surgery. The identification rate of re-SLNB varied from 29 to 100 % (mean 67 %). The success rate of re-SLNB depends on the method used for the previous axillary surgery and the number of lymph nodes harvested. Re-SLNB may be feasible even after mastectomy. A relationship between post-operative radiotherapy and identification of re-SLNB was not seen. A longer disease-free interval may correlate with a lower identification rate, but this finding is not definitive. Based on data regarding back-up dissection after re-SLNB, the accuracy of re-SLNB may be as good as SLNB in primary cases. Altered lymphatic drainage was reported in 2-89 % (mean 32 %) of cases. Because the altered lymphatic drainage can be detected only by lymphoscintigraphy, the radioisotope method, followed by lymphoscintigraphy, should be used. There are not many reported cases of axillary recurrence after re-SLNB, and the follow-up periods have been short. Because re-SLNB cases have a wide variety of backgrounds, it is necessary to accumulate a larger number of cases and to obtain data from longer follow-up period in order to make clear recommendations. PMID:24254062

Ikeda, Tadashi

2014-11-01

450

Extended-spectrum-?-lactamase-producing Escherichia coli as a cause of pediatric infections: report of a neonatal intensive care unit outbreak due to a CTX-M-14-producing strain.  

PubMed

Little information is available about pediatric infections caused by extended-spectrum-?-lactamase (ESBL)-producing Escherichia coli. We characterized an outbreak caused by a CTX-M-14-producing E. coli isolate in a neonatal intensive care unit (NICU) and studied other infections caused by ESBL-producing E. coli in non-NICU pediatric units. All children ?4 years old who were infected or colonized by ESBL-producing E. coli isolates between January 2009 and September 2010 were included. Molecular epidemiology was studied by phylogroup analysis, pulsed-field gel electrophoresis (PFGE), and multilocus sequence typing. Antibiotic resistance genes were analyzed by PCR and sequencing. Plasmids were studied by PFGE with S1 nuclease digestion and by incompatibility group analysis using a PCR-based replicon-typing scheme. Of the ESBL-producing E. coli isolates colonizing or infecting the 30 newborns, identical PFGE results were observed for 21 (70%) isolates, which were classified as CTX-M-14-producing E. coli of ST23