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Exploiting an Antivirus Interface  

Microsoft Academic Search

We propose a technique for defeating signature-based malware detectors by ex- ploiting information disclosed by antivirus interfaces. This information is lever- aged to reverse engineer relevant details of the detector's underlying signature database, revealing binary obfuscations that suce to conceal malware from the detector. Experiments with real malware and antivirus interfaces on Windows operating systems justies the eectiveness of our

Kevin W. Hamlen; Vishwath Mohan; Mohammad M. Masuda; Latifur Khan; Bhavani Thuraisingham


AVG Anti-Virus  

NSDL National Science Digital Library

Those who wish for an antivirus program that is both versatile and reliable should definitely consider this latest iteration of the AVG Anti-Virus program. With this program, visitors can be assured that AVG will look for new virus definitions on a daily basis and that it will also create an effective rescue disk in case a dire situation emerges. This website features a number of archived versions of the AVG software for users to choose from.



Vcatch Antivirus  

NSDL National Science Digital Library

Vcatch Antivirus is a program that will help users monitor their incoming emails and downloads in order to protect their computers from viruses and other such nefarious intruders. This program is integrated with Windows Explorer, and includes a detection engine that analyzes all files. Another helpful feature is that this application cooperates with anti-virus programs that are already installed on users' operating system. This program is compatible with all operating systems running Windows 95 and higher.


AMG Anti-Virus Free Edition 9.0  

NSDL National Science Digital Library

With this version of its popular product, AMG Anti-Virus is offering a few new notable highlights. For one, visitors can use the full-featured scheduling utility for automating tasks and checking for new definitions. This version of Anti-Virus also includes new anti-phishing detection techniques and an up-to-date link scanner. Users running Windows 2000 and newer as well as Linux will be able to use this application.


Evaluation and selection of an antivirus and content filtering software  

Microsoft Academic Search

Organizations and individuals today need to have a comprehensive virus protection policy to face the growing threats of the Internet computer viruses. Given the rise in micro viruses within the last three years many organizations have adopted a proactive management approach to the problem by installing an antivirus and content filtering software in order to identify and prevent computer viruses

Farrokh Mamaghani



Evolution of Computer Virus Concealment and AntiVirus Techniques: A Short Survey  

Microsoft Academic Search

This paper presents a general overview on evolution of concealment methods in computer viruses and defensive techniques employed by anti-virus products. In order to stay far from the anti-virus scanners, computer viruses gradually improve their codes to make them invisible. On the other hand, anti-virus technologies continually follow the virus tricks and methodologies to overcome their threats. In this process,

Babak Bashari Rad; Maslin Masrom; Suhaimi Ibrahim



Toward Automatic Discovery of Malware Signature for Anti-Virus Cloud Computing  

NASA Astrophysics Data System (ADS)

Security vendors are facing a serious problem of defeating the complexity of malwares. With the popularity and the variety of zero-day malware over the Internet, generating their signatures for detecting via anti-virus (AV) scan engines becomes an important reactive security function. However, AV security products consume much of the PC memory and resources due to their large signature files. AV cloud computing becomes a popular solution for this problem. In this paper, a novel Automatic Malware Signature Discovery System for AV cloud (AMSDS) is proposed to generate malware signatures from both static and dynamic aspects. Our experiments on millions-scale samples suggest that AMSDS outperforms most state-of-the-art automatic signature generation techniques of both industry and academia.

Yan, Wei; Wu, Erik


Preparation of an antitumor and antivirus agent: chemical modification of ?-MMC and MAP30 from Momordica Charantia L. with covalent conjugation of polyethyelene glycol  

PubMed Central

Background Alpha-momorcharin (?-MMC) and momordica anti-HIV protein (MAP30) derived from Momordica charantia L. have been confirmed to possess antitumor and antivirus activities due to their RNA-N-glycosidase activity. However, strong immunogenicity and short plasma half-life limit their clinical application. To solve this problem, the two proteins were modified with (mPEG)2-Lys-NHS (20 kDa). Methodology/principal findings In this article, a novel purification strategy for the two main type I ribosome-inactivating proteins (RIPs), ?-MMC and MAP30, was successfully developed for laboratory-scale preparation. Using this dramatic method, 200 mg of ?-MMC and about 120 mg of MAP30 was obtained in only one purification process from 200 g of Momordica charantia seeds. The homogeneity and some other properties of the two proteins were assessed by gradient SDS-PAGE, electrospray ionization quadruple mass spectrometry, and N-terminal sequence analysis as well as Western blot. Two polyethylene glycol (PEG)ylated proteins were synthesized and purified. Homogeneous mono-, di-, or tri-PEGylated proteins were characterized by matrix-assisted laser desorption ionization-time of flight mass spectrometry. The analysis of antitumor and antivirus activities indicated that the serial PEGylated RIPs preserved moderate activities on JAR choriocarcinoma cells and herpes simplex virus-1. Furthermore, both PEGylated proteins showed about 60%–70% antitumor and antivirus activities, and at the same time decreased 50%–70% immunogenicity when compared with their unmodified counterparts. Conclusion/significance ?-MMC and MAP30 obtained from this novel purification strategy can meet the requirement of a large amount of samples for research. Their chemical modification can solve the problem of strong immunogenicity and meanwhile preserve moderate activities. All these findings suggest the potential application of PEGylated ?-MMC and PEGylated MAP30 as antitumor and antivirus agents. According to these results, PEGylated RIPs can be constructed with nanomaterials to be a targeting drug that can further decrease immunogenicity and side effects. Through nanotechnology we can make them low-release drugs, which can further prolong their half-life period in the human body.

Meng, Yao; Liu, Shuangfeng; Li, Juan; Meng, Yanfa; Zhao, Xiaojun



Sistemas de cúmulos globulares extragalácticos  

NASA Astrophysics Data System (ADS)

Se describen las características de los sistemas de cúmulos globulares asociados a galaxias elípticas en una variedad de medios y, en particular, aquellas vinculadas con la distribución espacial, frecuencia específica y composición química. Esta discusión se hace dentro de un conjunto de esquemas orientados a explicar las primeras fases de la formación de las galaxias dominantes en cúmulos y del rol de los sistemas de cúmulos globulares en esos procesos.

Forte, J. C.



Microsoft Academic Search

Resumo :O artigo discute o sistema de Bretton Woods e a dinâmica do Sistema Monetário Internacional depois do abandono do padrão dólar-ouro. Sustenta-se que o colapso do sistema de Bretton Woods legitimou a estruturação de um padrão de riqueza subjugado ao plano das finanças, ao invés da produção e do emprego. Neste sentido, a idéia de ressurgimento do sistema Bretton




¿Qué es VAERS? El Sistema para Reportar Reacciones ...  

Center for Biologics Evaluation and Research (CBER)

Text Version... Sistema Sistema para para Reportar Reportar Reacciones Reacciones Adversas Adversas aa las las Vacunas Vacunas ... More results from


El Sistema and American Music Education  

ERIC Educational Resources Information Center

|The brainchild of Jose Antonio Abreu, El Sistema, a music education program for aspiring orchestra musicians launched in Venezuela for students of limited means and now spreading to other parts of the world, has become a subject of interest to music teachers and teacher educators in North America. This article examines a bit of the program's…

Lesniak, Melissa



Titre principale de la page  

Center for Drug Evaluation (CDER)

Text Version... induction at the protein level Page 7. 6 -Glutathione-adduct conjugation (LC-MS-MS). Troglitazone and GSH conjugates RT : 1 0 .0 0 - 1 9 .0 0 ... More results from


Los sistemas financieros a través de la teoría algebraica de autómatas  

Microsoft Academic Search

En este artículo se describen los sistemas financieros como familias de leyes financieras indizadas en el conjunto de los números enteros positivos, utilizando como herramienta el concepto algebráico de autómata. Se introducen dos tipos de sistemas financieros: los sistemas simplemente compuestos, que son una generalización de los sistemas simplemente multiplicativos, y los sistemas simplemente sumativos que también generalizan los sistemas

Salvador Cruz Rambaud



Avira AntiVir Personal-Free Antivirus  

NSDL National Science Digital Library

Viruses are quite pesky, and the free version of Avira AntiVir Personal can help those bedeviled by such afflictions. This application will help users locate and remove Trojans, worms, and backdoor programs. Users can customize their scans and they can elect to fully scan all hard drives. This version is compatible with computers running Windows 2000, XP, and Vista.



Malware and Antivirus Deployment for Enterprise IT Security  

Microsoft Academic Search

Threats to information security are spreading, from both outside and within an organization. Computer security has evolved so as the methods of identification, detection, and prevention of malware, only to be followed by a new set of threats that circumvent those safeguards. Internet and wide availability of toolsets and documentation exacerbates this problem by making malware development easy. As blended

Nadejda Belbus Vasilyevna; Sang-Soo Yeo; Eun-Suk Cho; Jeon-Ah Kim



Une nouvelle analyse multi-temporelle d'images satellitales, les résidus de l'Analyse en Composantes Principales. Un cas d'étude: une série d'images Landsat Thematic Mapper de la Camargue, France  

Microsoft Academic Search

Résumé. Les méthodes d'analyses de séries temporelles d'images satellitales sont nombreuses. Après une brève revue de ces méthodes, une nouvelle approche est proposée. Elle consiste à calculer les résidus de l'ACP (Analyse en Composantes Principales) du tableau des NDVI par la procédure suivante: calculer les variables NDVI à chacune des dates; construire le tableau de données espace × temps, par

T. Naizot; A. Dervieux; J. Thioulouse; M. F. Bellan



Une nouvelle analyse multi-temporelle d'images satellitales, les residus de l'Analyse en Composantes Principales. Un cas d'etude: une serie d'images Landsat Thematic Mapper de la Camargue, France  

Microsoft Academic Search

Resume´. Les methodes d'analyses de series temporelles d'images satellitales sont nombreuses. Apres une breve revue de ces methodes, une nouvelle approche est proposee. Elle consiste acalculer les residus de l'ACP (Analyse en Composantes Principales) du tableau des NDVI par la procedure suivante: calculer les variables NDVI achacune des dates; construire le tableau de donnees espace 6 temps, par accolement des

T. Naizot; Y. Auda; A. Dervieux; J. Thioulouse; et Bellan




Center for Drug Evaluation (CDER)

... Esta guía trata, principalmente desde un aspecto microbiológico, el examen y la evaluación de sistemas de agua de alta pureza que se utilizan ... More results from


El problema de estabilidad de los sistemas Hamiltonianos multidimensionales  

NASA Astrophysics Data System (ADS)

Se revisarán los aspectos básicos del problema de estabilidad de sistemans Hamiltonianos N-dimensionales, haciendo especial énfasis en los posibles mecanismos que dan lugar a la aparición de ``caos": overlap de resonancias, difusión de Arnol'd y otros procesos difusivos alternativos. Se mencionarán los aspectos aún no resueltos sobre la estabilidad de los sistemas con N > 2. Finalmente, se discutirá cuáles de estos mecanismos podrían tener alguna relevancia en la dinámica de sistemas estelares y planetarios.

Cincotta, P. M.


Discos de acresção em sistemas Be-X  

NASA Astrophysics Data System (ADS)

Alguns fenômenos de outbursts em Be-X sugerem a existência, mesmo que temporária, de um disco de acresção quando da passagem do objeto compacto pelo periastro orbital. Neste trabalho avaliamos a possibilidade de formação do disco de acresção em sistemas Be+estrela de neutrons e Be+anã branca, e a influência da excentricidade orbital na ocorrência deste fenômeno. Utilizamos a expressão analítica para o momento angular específico da matéria constituinte de um meio em expansão lenta, como é o caso do disco circunstelar das estrelas Be, proposta por Wang(1981), sob a condição básica de que o raio de circularização deva ser maior do que o raio de Alfvén. Concluímos que existe um limite para o período orbital do sistema acima do qual não é possível a formação do disco de acresção, e que este valor aumenta para sistemas com excentricidade orbital maior.

Lopes de Oliveira, R.; Janot-Pacheco, E.



Sistemas agroalimentarios localizados (SIAL): de la agroindustria al conglomerado  

Microsoft Academic Search

El objetivo de la investigación se centró en contrastar, como instrumento metodológico, el esquema teórico de los conglomerados para analizar la propuesta de los sistemas agroalimentarios localizados (SIAL) y derivar potenciales elementos clave de necesaria atención a la hora de promover un proceso evolutivo desde una actividad tradicional y semindustrial, hacia un competitivo conglomerado de agroindustrias rurales (AIR), ubicado territorialmente

Pina Zambrano; Henri Jesus




Microsoft Academic Search

El presente trabajo desarrolla la idea de una definición holística del turismo y explora los diferentes problemas que han tenido los abordajes precedentes. Bajo la premisa que el turismo es parte del sistema onírico cuya función es regular la práctica social de la sociedad, se establecen nuevas formas de estudiar el fenómeno que apelan a la comprensión inter-cultural y a

Maximiliano E. Korstanje



Sistema Planeta-Satélite. Simulación orbital y potenciales gravitatorios  

NASA Astrophysics Data System (ADS)

Se presenta un programa (desarrollado en Quick Basic 4.5) que simula, en tres dimensiones, el movimiento orbital de un satélite (o luna) alrededor de un planeta, al tiempo que calcula y grafica, en un plano, el potencial gravitatorio del sistema en función de la distancia al planeta. Para la simulación orbital, se emplea la matriz de transformación entre el sistema del planeta y el plano orbital. Para el cálculo y graficación del potencial se aplica un desarrollo en serie hasta el segundo orden, que da cuenta del efecto de achatamiento de los polos, en caso de que éste exista. Las longitudes de los ejes del planeta, la masa de éste y del satélite, sus tamaños aparentes, y los parámetros orbitales son introducidos por el usuario.

Medina, C.; Carrillo, M.


El nuevo sistema de financiación autonómica. Una visión crítica. \\/The New Regional Financing System. A Critical Review  

Microsoft Academic Search

La reforma del sistema de financiación aprobada en julio del año 2009 es esencialmente diferente de las reformas de los sistemas de financiación anteriores. Por un lado, no ha venido exigida por el tradicional plazo de caducidad de los sistemas de financiación cada cinco años, sino por circunstancias esencialmente políticas. Por otro lado, se ha dicho que el nuevo sistema




Sistema de gestión de competencias basados en capacidades y recursos y su relación con el sistema SECI de gestión del conocimiento  

Microsoft Academic Search

Este estudio parte de la investigación “Acceso de la pequeña empresa a las redes de innovación y conocimiento”, y pretende encontrar la relación existente entre los sistemas de gestión de competencias basado en capacidades y recursos y el sistema SECI de gestión del conocimiento, realizadas por las pequeñas empresas del Urola Medio. El estudio se concentra en el desarrollo de




Estudo e aplicação do código de desembaraçamento espectral - Korel - em sistemas triplos  

NASA Astrophysics Data System (ADS)

O código KOREL é uma ferramenta adicional eficiente para a determinação simultânea de parâmetros orbitais espectroscópicos para o desembaraço de espectros individuais de sistemas estelares com até cinco componentes. Estudos já realizados (Torres,KBV,2002, Dissertação de Mestrado DF-ICEx-UFMG) mostram as limitações, aplicabilidade e eficiência do código para sistemas com duas componentes. Apresentamos, neste trabalho, a continuação dos estudos para sistemas com três componentes (sistemas hierárquicos), utilizando espectros sintéticos "gabaritos" de estrelas individuais em órbitas cujos parâmetros são conhecidos "a priori". Geramos os espectros compostos e verificamos como o código reproduz os parâmetros orbitais e espectros individuais em diversas situações físicas. É apresentado, ainda, uma discussão da aplicabilidade do código em sistemas reais como RV Crateris (Machado,ACM,1997, Dissertação de Mestrado DF-ICEx-UFMG), um sistema triplo cujas componentes eclipsantes estão, provavelmente, ainda na fase pré-sequência principal.

Torres, K. B. V.; Vaz, L. P. R.



Teoria e institucionalização dos sistemas partidários após a terceira onda de democratização  

Microsoft Academic Search

Resumo Este artigo examina duas diferenças entre os sistemas partidários das democracias industriais avançadas e os de países menos desenvolvidos, particularmente em termos do nível de institucionalização. O argumento geral é que os sistemas partidários dos países menos desenvolvidos são menos institucionalizados. De modo mais específico, mostramos primeiro que a maioria das democracias e semi-democracias em países menos desenvolvidos têm

Scott Mainwaring; Mariano Torcal




Microsoft Academic Search

Resumen Todo sistema de enseñanza debe complementarse con algún tipo de evalua ción del conocimiento adquirido por los alumnos, ya que de otra manera no podría identificarse el éxito o fracaso en el proceso de aprendizaje. No en vano, en el desarrollo de sistemas educativos informatizados, el módulo de evaluación recibe cada vez más importancia. En este artículo se plantea

Javier López-Cuadrado; Sara Sanz; Mikel Villamañe; Silvia Sanz



Microsoft Academic Search

Este artículo trata sobre el papel preponderante que juegan los Auxiliares de la Justicia que cobra mayor relevancia dentro del engranaje del modelo del Sistema Acusatorio, en los Procesos Orales, garantista en Contra posición con el actual Sistema Inquisitivo destacando el trabajo, capacidad y preponderancia de Estos colaboradores muchas veces anónimos en el Sistema actual, pero que serán de suma

Ivanovha Lamela



Cyber Security Challenges: Designing Efficient Intrusion Detection Systems and Antivirus Tools  

Microsoft Academic Search

Abstract: Introduction to Intrusion Detection SystemsIntrusion detection an important component of information security technology helps indiscovering, determining, and identifying unauthorized use, duplication, alteration, anddestruction of information and information systems. Intrusion detection relies on the assumptionthat information and information systems under attack exhibit several distinguishable behavioralpatterns or characteristics to that of the normal ones. Though intrusion detection...

Srinivas Mukkamala; Andrew Sung; Ajith Abraham


Research on the anti-virus system of military network based on cloud security  

Microsoft Academic Search

With the stepping up of information technology in military, information is increasingly playing a key role which enhance efficiency for military command, training, battle. Connecting With the military networks among in army universities, research institutes, the size of the military information network is rapidly expanding, while the Hidden danger of information security also increase with the virus develop from the

Wang Xin; Huang Ting-lei; Ren Zhi-jian



Chemical constituents from Lobelia chinensis and their anti-virus and anti-inflammatory bioactivities.  


In total, forty six compounds, including the novel compound lobechine (1), were characterized from the methanol extracts of Lobelia chinensis. The chemical structures of known metabolites were identified by comparing their spectroscopic and physical data with compounds reported in the literature. The structure of lobechine (1) was comprehensively established with the aid of 1D and 2D NMR spectroscopic analyses. In addition, selected isolates were screened for their inhibition of HSV-1 replication, superoxide anion generation, and elastase release. Among the tested compounds, scoparone (10) exhibited significant inhibition of superoxide anion generation with IC(50) of 6.14 ± 1.97 ?M and lobechine (1) exhibited moderate inhibition of elastase release with IC(50) of 25.01 ± 6.95 ?M, respectively. PMID:21656355

Kuo, Ping-Chung; Hwang, Tsong-Long; Lin, Ying-Ting; Kuo, Yuh-Chi; Leu, Yann-Lii



A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair  

PubMed Central

Summary Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) and the associated proteins (Cas) comprise a system of adaptive immunity against viruses and plasmids in prokaryotes. Cas1 is a CRISPR-associated protein that is common to all CRISPR-containing prokaryotes but its function remains obscure. Here we show that the purified Cas1 protein of Escherichia coli (YgbT) exhibits nuclease activity against single-stranded and branched DNAs including Holliday junctions, replication forks, and 5?-flaps. The crystal structure of YgbT and site-directed mutagenesis have revealed the potential active site. Genome-wide screens show that YgbT physically and genetically interacts with key components of DNA repair systems, including recB, recC and ruvB. Consistent with these findings, the ygbT deletion strain showed increased sensitivity to DNA damage and impaired chromosomal segregation. Similar phenotypes were observed in strains with deletion of CRISPR clusters, suggesting that the function of YgbT in repair involves interaction with the CRISPRs. These results show that YgbT belongs to a novel, structurally distinct family of nucleases acting on branched DNAs and suggest that, in addition to antiviral immunity, at least some components of the CRISPR-Cas system have a function in DNA repair.

Babu, Mohan; Beloglazova, Natalia; Flick, Robert; Graham, Chris; Skarina, Tatiana; Nocek, Boguslaw; Gagarinova, Alla; Pogoutse, Oxana; Brown, Greg; Binkowski, Andrew; Phanse, Sadhna; Joachimiak, Andrzej; Koonin, Eugene V.; Savchenko, Alexei; Emili, Andrew; Greenblatt, Jack; Edwards, Aled M.; Yakunin, Alexander F.



El cáncer según su ubicación en el cuerpo: Sistema reproductor femenino

In English En español In English En español Para buscar un tipo de cáncer, seleccione su ubicación en el cuerpo — Aparato locomotor Aparato respiratorio y tórax Cabeza y cuello Célula germinativa Cerebro y sistema nervioso Digestivo y gastrointestinal


Conhecimento e inovação em sistemas locais de produção de revestimentos cerâmicos e os novos desafi os da concorrência internacional  

Microsoft Academic Search

RESUMO Este trabalho tem como objetivo contribuir para a compreensão das novas dinâmicas de geração de conhecimento e inovação em sistemas loc ais de produção a partir dos desafi os da concorrência internacional, por meio da realização de estudos em dois sistemas locais da indústria de cerâmica de revestimento no Brasil, um localizado em Santa Gertrudes\\/SP e outro em Criciúma\\/SC.

Gabriela Scur FEI; Renato Garcia EPUSP




Microsoft Academic Search

Nas últimas décadas o Brasil tem confirmado seu importante papel na produção agrícola mundial. Apoiando esta posição encontra-se a utilização da informática pelas empresas rurais e o destaque para a utilização dos sistemas de informações gerenciais (SIGs). O objetivo deste artigo foi reunir e discutir informações sobre alguns fatos da história do desenvolvimento da agroinformática no Brasil enfocando-se a participação

Henri Cocaro; Jose Carlos dos Santos Jesus



La Evolución de los Sistemas de Pagos de Bajo Valor en el Perú  

Microsoft Academic Search

El trabajo describe el desarrollo de los sistemas interbancarios de pago de bajo valor en el Perú en el período 2005-2010. Se destaca que las transferencias de crédito han tenido una alta tasa de crecimiento en los últimos cinco años, aunque los valores y volúmenes alcanzados son aún más bajos que los obtenidos en la región. Los bajos niveles de

Marylin Choy; Victor Roca



The Failure of Memory and Literature in Primo Levi's Il sistema periodico  

Microsoft Academic Search

?In Il sistema periodico, Primo Levi searches for an overarching meaning to his life and seeks to establish symbolically a coherence between experiences. This is not a small task for a Holocaust survivor who began his writing career with the publication of Se questo è un uomo, an act of witnessing. In general, survivors of Nazi concentration camps express a

Elizabeth Scheiber



Detección de anticuerpos antineuronas en pacientes con enfermedades del sistema nervioso: estudio preliminar  

Microsoft Academic Search

RESUMEN Con el objetivo de profundizar en la patogenia de enfermedades que involucren al sistema nervioso central, un colectivo de los laboratorios se dio a la tarea de detectar autoanticuerpos antineuronas en pacientes con estas enfermedades mediante la técnica de inmunofluorescencia indirecta. Se analizaron 31 sueros de pacientes y 72 controles, se obtuvo como resultado una sensibilida d de 77

Raisa Jofra Hernández; Arturo Muster; Roberto Alegre Mendez


El Sistema de Formas en Colores for Teaching Grammar in Spanish  

ERIC Educational Resources Information Center

Sistema de formas en colores (SFC) is a symbols-based system for teaching Spanish grammatical structures and concepts within a communicative context in the elementary school. The (ACTFL) Standards for Foreign Language Learning: Preparing for the 21st Century states that, "While grammar and vocabulary are essential tools for communication, it is…

Nailon, James



Social Responsibility and Community Development: Lessons from the Sistema de Aprendizaje Tutorial in Honduras  

ERIC Educational Resources Information Center

This article extends understanding of the connections between education, social capital, and development through a mixed-methods case study of the Sistema de Aprendizaje Tutorial, or SAT, an innovative secondary-level education system. The quantitative dimension of the research used survey measures of social responsibility to compare 93 SAT…

Honeyman, Catherine A.



Especificação de Requisitos de Qualidade de Serviço em Sistemas Abertos: A Linguagem QSL  

Microsoft Academic Search

Resumo Algumas aplicações distribuídas não funcionam adequadamente sem que garantias de qualidade sejam impostas aos serviços fornecidos pela rede de comunicação e pelas plataformas de execução. Estas aplicações necessitam de suporte a qualidade de serviço (QoS) para funcionar corretamente, obrigando que requisitos temporais, de confiabilidade e de segurança sejam observados pelo sistema. Este trabalho apresenta uma linguagem para especificação de

Frank A. Siqueira



Social Responsibility and Community Development: Lessons from the Sistema de Aprendizaje Tutorial in Honduras  

ERIC Educational Resources Information Center

|This article extends understanding of the connections between education, social capital, and development through a mixed-methods case study of the Sistema de Aprendizaje Tutorial, or SAT, an innovative secondary-level education system. The quantitative dimension of the research used survey measures of social responsibility to compare 93 SAT…

Honeyman, Catherine A.



Cuadro de mando y sistemas de información: herramientas estratégicas para la gestión medioambiental corporativa  

Microsoft Academic Search

En la actualidad protección del ambiente es un nuevo e importante objetivo estratégico de las empresas cubanas y del mundo. La información medioambiental se vuelve cada vez más relevante para las decisiones económicas, por lo que es necesario manejarla de manera oportuna. Muchas entidades presentan Sistemas de Gestión Medioambientales según NC ISO 14000 que se quedan en fases meramente declarativas

Frank Medel; Lourdes García; Liesby Gómez; Rebeca Pentón




Microsoft Academic Search

A biomassa é importante insumo para uso energético, porque introduz desenvolvimento local e sustentável, gera energia e com os sub-produtos proporciona renda. Esse ciclo tem como principal resultado alterações positivas na qualidade de vida para as populações envolvidas, o que é particularmente importante nas pequenas comunidades sem atendimento elétrico, sobretudo na Amazônia que têm diversas localidades isoladas dos sistemas convencionais

Artur de Souza Moret; Sinclair Mallet Guy Guerra



Arboviroses : notions générales et particularités des principales infections  

Microsoft Academic Search

Arboviral diseases are viral, vectorial and arthropod borne illness. Domestic or wilde animals, vectors and humans are the reservoir hosts. Human transmission is mainly accidental. Most of arboviral diseases are situated in tropical countries. The two main european arboviral diseases are tick borne encephalitis and West Nile fever. On account of population growth, intimate contact between human and vectors, antivectorial

Pierre Abgueguen; Eric Pichard




Microsoft Academic Search

Two male statues, recorded in the 1640 inventory, are located in important positions at the west wall of the Palazzo Lancellotti. The figure on the left recalls the typology of the so-called Discoforos, a work by Polykleitos created around 450 B.C. and reproduced in various forms in the Roman imperial period. The sculpture in question, amply reintegrated, can be attributed

Daniela Candilio



Microsoft Academic Search

I sistemi di monitoraggio dei fenomeni franosi richiedono, nella fase preliminare, la conoscenza del tipo di movimento in atto o potenzialmente possibile nell'area esaminata, in modo da poter selezionare il sistema più efficace; è quindi fondamentale conoscere le caratteristiche geologiche del sito d'interesse. La seconda fase consiste nell'installazione degli strumenti adatti e nell'esecuzione della misure di monitoraggio: queste ultime possono

L. Sambuelli; M. Mondin; S. Franchi; C. Strobbia; G. Lollino


Implementando o Agente de Base de Domínio do Sistema Tutor Inteligente PAT2Math  

Microsoft Academic Search

Resumo. A matemática é considerada uma área complexa por muitos alunos, que em geral consideram seus conteúdos muito abstratos, não compreendendo sua aplicação ou não conseguindo relacioná-los com seu dia-a-dia. Mesmo assim, poucos são os ambientes de aprendizagem capaz de auxiliá-los. Faz-se necessário um sistema que leve em consideração as emoções do educando, visto que grande parte das dificuldades enfrentadas

Gabriel Mello; Talvany Carlotto; Geiseane Rubi; Henrique M. Seffrin; Patrícia A. Jaques


O efeito do achatamento nos pontos de equilíbrio e na dinâmica de sistemas coorbitais  

NASA Astrophysics Data System (ADS)

Neste trabalho analisamos o efeito do achatamento do corpo principal nos pontos de equilíbrio lagrangianos e na configuração de órbitas girino-ferradura. Enfatizamos os sistemas coorbitais de satélites de Saturno, pois se encontram em relativa proximidade com o planeta, em que o efeito do achatamento se torna mais evidente. O estudo é dividido em três etapas independentes. Na primeira fase analisamos as equações de movimento do problema restrito de três corpos considerando o efeito do achatamento, e através do balanceamento de forças buscamos a nova configuração dos pontos de equilíbrio lagrangianos. Concluímos, nesta etapa, que os pontos de equilíbrio estáveis apresentam um pequeno deslocamento definido pelo parâmetro de achatamento, não podendo ser mais representados por triângulos eqüiláteros. Aplicamos este resultado aos satélites coorbitais de Tetis e Dione, encontrando as posições de equilíbrio levemente deslocadas em relação ao caso sem achatamento. Na segunda fase visamos o sistema Saturno-Jano-Epimeteu, que por se tratar de um sistema de massas comparáveis, optamos por desenvolver as equações de Yoder et al (Icarus 53, pág 431-443, 1983), que permitem determinar os pontos de equilíbrio e a amplitude de oscilação angular das órbitas girino-ferradura para o problema não-restrito de três corpos, porém, no nosso estudo consideramos o efeito do achatamento do corpo principal nestas equações. Encontramos que a distância angular entre satélites, quando em posição de equilíbrio estável, diminui quanto maior for o parâmetro de achatamento do corpo principal. Além disso, a órbita de transição girino-ferradura possui largura angular menor em relação ao caso sem achatamento. Por fim, realizamos integrações numéricas para os casos reais de coorbitais de Saturno comparando com os resultados analíticos. Nestas integrações simulamos diversas órbitas girino-ferradura com diferentes parâmetros de achatamento, utilizando condições iniciais corrigidas para a presença do achatamento.

Mourão, D. C.; Winter, O. C.; Yokoyama, T.



Correlação de longo alcance em sistemas binários de raios-x usando remoção de flutuações  

NASA Astrophysics Data System (ADS)

Neste trabalho é proposta uma metodologia de analise de series temporais de fontes astrofísicas, baseada no método proposto por Peng et al. (1994) e Liu et al. (1999), o qual consiste na idéia de que uma série temporal correlacionada pode ser mapeada por um processo de busca de auto-similaridades em diversas escalas de tempo n. Removendo as eventuais tendências e integrando o sinal observado, é obtida uma medida do desvio médio quadrático das flutuações do sinal integrado F(n)~na, onde a representa o fator de escala associado com a auto-similaridade da correlação de longo alcance do sinal. Baseado nos valores obtidos de a, é possível distinguir entre os casos de sinais não-correlacionados, tipo ruído branco (a = 0,5), sinal anti-persistentes (a < 0,5) e sinal persistente (a > 0,5). Usando esta metodologia, foram analisadas 129 curvas de luz de sistemas binários de raios-X, provenientes do banco de dados públicos de observações feitas pelo instrumento All Sky Monitor, a bordo do satélite Rossi X-Ray Timing Explorer (ASM-RXTE). Foram identificadas a presença de a'0,5 em mais de 90% dos sistemas estudados, implicando em dizer que as flutuações de intensidade observadas apresentam correlação de auto-similaridade, sem entretanto, indícios de apresentarem uma escala de tempo característica das flutuações de intensidade. Sistemas onde são observadas erupções (flares), apresentam sistematicamente a > 0,5, característica esta, possivelmente associada com persistência das flutuações de densidade de disco ou taxa de acréscimo de massa. Os sistemas com curvas de luz onde nao são observadas as erupções apresentam uma distribuição normal centrada em a~0,62+/-0,10. Referências ¾ Peng, C.-K., Buldyrev, S.V., Havlin, S., Simons, M., Stanley, H.E., e Goldberg, A.L., Phys. Rev. E, (49), 1685 (1994). ¾ Liu, Y., Gopikrishnan, P., Cizeau, P., Meyer, M., Peng,C.-K., e Stanley, H.E., Phys. Rev. E, (60), 1390 (1999).

Pereira, M. G.; Moret, M. A.; Zebende, G. F.; Nogueira, E., Jr.



A rapid immune plaque assay for the detection of Hendra and Nipah viruses and anti-virus antibodies  

Microsoft Academic Search

Rapid immune plaque assays have been developed to quantify biohazard level 4 agents Hendra and Nipah viruses and detect neutralising antibodies to both viruses. The methods rely on the fact that both viruses rapidly generate large syncytia in monolayers of Vero cells within 24 h and that monospecific antiserum to the Hendra virus phosphoprotein (P) detects that protein in both

Gary Crameri; Lin-Fa Wang; Christopher Morrissy; John White; Bryan T Eaton



Securing PCs and Data in Libraries and Schools: A Handbook with Menuing, Anti-Virus, and Other Protective Software.  

ERIC Educational Resources Information Center

|This handbook is designed to help readers identify and eliminate security risks, with sound recommendations and library-tested security software. Chapter 1 "Managing Your Facilities and Assessing Your Risks" addresses fundamental management responsibilities including planning for a secure system, organizing computer-related information, assessing…

Benson, Allen C.



Microsoft Academic Search

Esse artigo investiga os efeitos de notícias a respeito do mau da vaca louca ou BSE sobre o consumo das carnes bovina, suína e de aves nos EUA. Presume-se que o sistema nacional de identificação animal (NAIS) poderia em tese atenuar a percepção de risco dos consumidores sobre contrair o mau da vaca louca ao consumir carnes. Sistemas de equações

Moises de Andrade Resende Filho; Brian L. Buhr



Avaliação dos sistemas de classificação e codificação das bacias hidrográficas brasileiras para fins de planejamento de redes hidrométricas  

Microsoft Academic Search

The available classification and codification systems of river basin used by ANEEL, ANA, IBGE, SRH e CNRH were evaluated and the Otto Pfafstetter' system was selected as the more appropriate in the planning of hydrometric networks. Palavras-chave: river basin, classification and codification systems, hydrometric networks, Otto-basin, bacias hidrográficas, sistemas de classificação e codificação, redes hidrométricas, ottobacias.

Wougran Soares Galvão


Los impuestos en la época de la Independencia, su impacto social, evolución e implicaciones en el sistema tributario actual  

Microsoft Academic Search

resumen la evolución histórica de los tributos en colombia se encuentra inmersa en una serie de acontecimientos que hacen parte de la historia patria. el sistema impositivo colombiano fue implementado por españa durante la colonización a semejanza del aplicado en dicho país; el incremento de los impuestos para financiar sus actividades y las guerras que sostenía por la lucha de

Constanza Loreth Fajardo Calderón; Dora Cecilia Suárez Amaya



Estudios regionales y sistemas de información geográfica: Mesitas de El Colegio- Cundinamarca Colombia Sudamérica-1996-2002  

Microsoft Academic Search

Resumen Los sistemas GIS, utilizados ya hace algunos años para los estudios geográficos, pueden ser usados en nuevos campos de documentación y en nuevos ambientes de investigación. Ellos transforman los documentos en imágenes permitiendo ubicárseles espacialmente, recolectando de esta manera información especifica en bases de datos de diferente origen. Con estas nuevas herramientas, el equipo de investigación de arte rupestre

Guillermo Muñoz


Relazioni quantitative per lo stato tensionale di un qualunque sistema continuo e per la deformazione di un corpo elastico in equilibrio  

Microsoft Academic Search

Sunto.  Si stabiliscono delle disuguaglianze relative alle caratteristiche di tensione di un qualunque sistema continuo. Nel caso\\u000a dei corpi elastici omogenei communque anisotropi ne seguono disuguglianze relative alle deformazioni.

Giuseppe Grioli



Transferências orbitais dentro do modelo quase bicircular no sistema Terra-Lua-Sol  

NASA Astrophysics Data System (ADS)

O problema quase bicircular planar consiste na determinação da dinâmica de um corpo, de massa desprezível, que se move sob o campo gravitacional de três corpos. No caso estudado, o quarto corpo é considerado um satélite artificial e os demais são a Terra, a Lua e o Sol, formando o sistema de três corpos. Este modelo permite a construção de uma hamiltoniana similar a do problema restrito de três corpos (PRTC), incluindo termos periódicos não autônomos, provenientes da presença do Sol, portanto pode ser entendido como uma perturbação ao PRTC. Suas órbitas periódicas aparecem isoladas e possuem o mesmo período solar. Os pontos de equilíbrio colineares possuem o mesmo caráter de estabilidade linear dos pontos lagrangianos (L1, L2 e L3) do PRTC, sendo do tipo sela x centro x centro, instável na direção x e estáveis nas direções y e z. As órbitas periódicas tridimensionais ao redor do ponto colinear é chamada órbita Halo. O objetivo deste trabalho é determinar órbitas de transferências de baixo consumo de combustível para um veículo espacial partindo de uma órbita de estacionamento ao redor da Terra em direção a uma órbita Halo do ponto L1, situado entre a Terra e Lua. Esta tarefa pode ser transformada no problema de valor de contorno: dado um ponto inicial na órbita de estacionamento, um ponto final na órbita halo e o tempo de transferência, deseja-se obter a trajetória que liga estes dois pontos e que minimize os incrementos de velocidade do veículo. Essas transferências são realizadas baseadas no método de Lambert e analisadas de modo a fornecer um baixo consumo. Posteriormente, é feita uma comparação de consumo com as órbitas de transferência equivalentes do PRTC.

Corrêa, A. A.; de Almeida Prado, A. F. B.; Stuchi, T. J.; Beaugé, C.



Propuesta de modificación del Sistema de Iluminación en el área de Clasificado Envasado de la Fábrica de Tabacos para la Exportación de Camajuaní  

Microsoft Academic Search

En el presente trabajo se modifica el Sistema de Iluminación establecido en el área de Clasificado y Envasado de Tabaco perteneciente al Departamento de Terminado de la Fábrica de Tabaco Torcido a mano destinado a la Exportación de Camajuaní, debido a que en estudios realizados, como encuestas a los trabajadores y observaciones en el área, se determinó que existen dificultades

Alexis Águila Espinosa



A System Administrator's Guide to Implementing Various AntiVirus Mechanisms: What to do When a Virus is Suspected On a Computer Network  

Microsoft Academic Search

This paper, presented in the form of sample guidelines\\/procedures, will express in much detail the steps, techniques and methods of defense utilized\\/implemented in the detection, investigation and tracing of a suspected computer virus. Proposed courses of action will be discussed. The effectiveness of these actions, as well as the use and effectiveness of established mechanisms of defense will be evaluated.

Robert B. Fried



The non-haemadsorbing African swine fever virus isolate ASFV\\/NH\\/P68 provides a model for defining the protective anti-virus immune response  

Microsoft Academic Search

African swine fever virus ASFV\\/NH\\/P68 is a naturally occurring, non-haemadsorbing and non-fatal isolate. Longitudinal clinical and immunological studies on 31 pigs inoculated oronasally or intramuscularly with this isolate defined two discrete groups of animals: those developing ASF chronic type lesions and those remaining asymptomatic. Animals developing lesions had viraemia and fever late after infection, NK activity levels close to that

Alexandre Leita; Clara Cartaxeiro; Ricardo Coelho; Benedita Cruz; R. M. E. Parkhouse


Influencia de la formulación de la glutamina en sus efectos sobre los sistemas antioxidantes y de destoxificación hepática en la rata  

Microsoft Academic Search

Resumen Objetivos: El objeto de este estudio es valorar el efecto que la suplementación de dietas parenterales con L-gluta- mina o con L-alanil-L-glutamina ejerce sobre el equilibrio oxidante\\/antioxidante hepático y sobre los sistemas de des- toxificación mediados por el citocromo P-450 en ratas. Material y métodos: Los animales (n = 60) se cateteri- zaron centralmente y se asignaron aleatoriamente a

J. J. Ortiz de Urbina; F. Jorquera; J. Culebras; C. Villares; J. González-Gallego; M. J. Tuñón



Principales características de la pandemia por el nuevo virus influenza A (H1N1)  

Microsoft Academic Search

At the end of March 2009, a new influenza virus A (H1N1) of porcine origin was isolated in two children from California presenting flu-like clinical syndrome. This virus was initially disseminated in Mexico and US and then worldwide. Eight weeks later, it had reached 74 countries with almost 30,000 cases and had caused 145 deaths. The virus had also sustained

Josep Vaqué Rafart; Julita Gil Cuesta; María Brotons Agulló



Estimación económica de las principales deseconomías presentes en el Gran Área Metropolitana (GAM) de Costa Rica  

Microsoft Academic Search

La Gran Área Metropolitana (GAM) de Costa Rica ha experimentado transformaciones en su estructura y composición, reflejado en una serie de cambios en relación a la dinámica del crecimiento poblacional, de su estructura productiva y en el uso del espacio geográfico. Estas transformaciones han generado beneficios positivos, sin embargo, han desarrollado una serie elementos negativos dado el grado de saturación

Marco Otoya Chavarría



Principales resultados del Estudio Nacional de Exámenes de pulmón (NLST): Síntesis

El 4 de noviembre de 2010, el Estudio Nacional de Exámenes de Pulmón dio a conocer resultados iniciales que indican que hubo 20% menos muertes por cáncer de pulmón entre los participantes del estudio evaluados con tomografía computarizada espiral de baja dosis (también conocida como tomografía computarizada helicoidal) que en los participantes que fueron evaluados con radiografías de pecho.


Clasificación de petróleos mexicanos mediante cromatografía de gases y análisis de componentes principales  

Microsoft Academic Search

Resumen. En el presente trabajo se evaluó la metodología tradicional para caracterizar y clasificar petróleos a partir de los hidrocarburos con 7 átomos de carbono. Con esta finalidad se utilizó un juego de datos cromatográficos de 43 muestras de aceites colectados en tres importantes áreas productivas de México. Se encontró que dicha metodología no permite clasificar claramente las muestras de

Comunicación Técnica; Nora K. Cañipa-Morales; Carlos A. Galán-Vidal; José A. Pérez-Ortiz; Mario A. Guzmán-Vega




Microsoft Academic Search

This work proposes the construction and evaluation of an hypermedia system for astronomy teaching, which will be performed with the cooperation of geography and science school teachers. The system aims to provide a suitable environment to help the reconstruction and reorganization of knowledge by the teachers. It is expected they be able to rethink previous concepts, as the software leads




Microsoft Academic Search

Resumen En este estudio se evaluó la biomasa aérea en seis diferentes sistemas agroforestales de cacao (Theobroma cacao L.) asociado con especies forestales maderables y frutales; con el propósito de conocer el potencial de captura de carbono por cada sistema. El estudio se realizó en dos diferentes sitios ubicados en la región San Martín (provincias de San Martín y Mariscal

Juanita Y. Concha; Julio C. Alegre; Vicente Pocomucha


InfluêncIa da fonte lumInosa na mIcroInfIltração de doIs sIstemas adesIvos The lighT source influence on microleakage of Two adhesive sysTems  

Microsoft Academic Search

resumo Introdução: Avalia-se a microinfiltração marginal in vitro em esmalte e dentina de restaurações em resina composta, empregando-se dois sistemas adesivos convencionais, tendo-se como variáveis duas fontes de energia, um aparelho de luz halógena e um LED. Método: Para tanto, dipôs-se de 40 molares humanos hígidos em que se realizou o preparo cavitário tipo classe V nas faces vestibular e

Paulo Fonseca; Menezes Filho; Elizabeth Galamba; Fernandes Abreu; Juliana Raposo Souto Maior; Rodivan Braz


Evaluating the improvements of the BOLAM model of the ISPRA Sistema Idro-Meteo-Mare on the December 2008 flood event in Rome  

NASA Astrophysics Data System (ADS)

The Sistema Idro-Meteo-Mare is an integrated meteo-marine forecasting chain for the Mediterranean basin. The recent update of the meteorological segment, based on the hydrostatic BOlogna Limited Area Model (BOLAM), gives the opportunity for a comparative verification study on a Mediterranean cyclone. The 10-12 December 2008 flood event in Rome has been chosen as case study. This disastrous event was claimed to be an extreme one by mass-media; however, its return time is shown here to be about 5 years. The Mediterranean cyclone responsible for the flood offers a tough case study in order to verify the model's ability in reproducing the evolution of meso-synoptic features in the Mediterranean environment. A qualitative comparison, employing satellite data and derived products, is performed. Results suggest that the upgraded model provides a more realistic representation of the cyclone warm sector - where the main rainfall peak took place - whereas the error in the cyclone trajectory and shape evolution is less affected by the BOLAM improvement.

Casaioli, M.; Lastoria, B.; Mariani, S.; Bussettini, M.



Una aproximación a las principales dificultades léxicas y morfo-sintácticas para aprender inglés de los hablantes hispanos  

Microsoft Academic Search

This article points out the main lexical and morpho-syntactic errors Spanish speakers have when they learn English. These errors have been observed in a group of Mexican students in USA. The paper will illustrate with examples problems such as Spanglish, generalization, mother tongue influence, etc. so that lecturers see these errors as a natural part of students' learning process. Some



How to Keep Your Campus Safe from Infection  

ERIC Educational Resources Information Center

|In this article, the author explains how antivirus programs work. He also explains how performances of various antivirus programs vary from one to another. He also takes a look at 13 antivirus programs and explains which of these will keep computers protected. These programs include: (1) Sophos Anti-Virus Version 3.86.2; (2) McAfee VirusScan 9.0;…

Brown, Scott



How to Keep Your Campus Safe from Infection  

ERIC Educational Resources Information Center

In this article, the author explains how antivirus programs work. He also explains how performances of various antivirus programs vary from one to another. He also takes a look at 13 antivirus programs and explains which of these will keep computers protected. These programs include: (1) Sophos Anti-Virus Version 3.86.2; (2) McAfee VirusScan 9.0;…

Brown, Scott



Apuntes sobre el Sistema Interamericano  

Microsoft Academic Search

El primer artículo nos plantea uno de los más importantes aportes de la Corte Interamericana de Derechos Humanos, es la construcción de toda una teoría respecto de las normas que integran el derecho imperativo internacional. El segundo contempla a la igualdad que ha sido una preocupación de todas las ciencias sociales y humanas, incluyendo la ciencia jurídica que, reflejando la

Autores varios


Patologie del sistema nervoso vegetativo  

Microsoft Academic Search

\\u000a I disturbi della sudorazione comprendono l’iperidrosi, caratterizzata da esagerato incremento dell’attività sudoripara, l’ipoidrosi\\u000a e l’anidrosi, nelle quali si verifica una patologica riduzione o assenza della secrezione ghiandolare.

Jessica Mandrioli; Pietro Cortelli


A modernização do sistema editorial  

Microsoft Academic Search

2 Encerramos mais um ano de intenso trabalho na Revista Latino-Americana de Enfermagem (RLAE), marcado pelo contínuo e crescente fluxo de manuscritos recebidos para publicação. Em 2005 recebemos 248 manuscritos, dos quais 10% foram aceitos para publicação, 78% estão em processo de avaliação, 12% foram recusados. Compondo o volume 13 da RLAE, foram publicados 143 artigos em seis números regulares

Maria Helena Palucci Marziale; Isabel Amélia Costa Mendes



LEVANTAMENTO PEDOLÓGICO E SISTEMA DE INFORMAÇÕES GEOGRÁFICAS NA AVALIAÇÃO DO USO DAS TERRAS EM SUB-BACIA HIDROGRÁFICA DE MINAS GERAIS 1 Pedologic survey and geographic information system for evaluation of land use within a small watershed, Minas Gerais State, Brazil  

Microsoft Academic Search

RESUMO A aptidão agrícola das terras consiste em uma classificação técnica que identifica o potencial agrícola de utilização das mesmas, considerando as limitações do solo em níveis de manejo diferenciados a partir das informações geradas em um levantamento pedológico. O cruzamento dos dados de aptidão agrícola e uso atual das terras em ambiente SIG (Sistema de Informações Geográficas) consiste numa

Michele Duarte de Menezes; Nilton Curi; João José Marques; Carlos Rogério de Mello; Alexandre Romeiro de Araújo



Microsoft Academic Search

The computation of principal curvatures and directions is important in different fields like computer vision, pattern recognition and 3D object reconstruction. Curvatures and directions are properties that must be estimated in discrete form, since the rendering primitives are data points that have neither interconnection nor orientation. This paper present a method to estimate principal curvatures and directions from an unorganized-points




Zoonosis: Principales Enfermedades Transmisibles de los Animales al Hombre - Causas, Tratamiento y Prevencion (Zoonosis: Principal Diseases Transmittable from Animals to Humans - Causes, Treatment and Prevention).  

National Technical Information Service (NTIS)

The document provides causes, treatment and prevention information on 19 zoonoses--animal diseases that can be transmitted to man. These diseases are: mastitis; cowpox; sacropsiliasis; rabies; trichinosis; tapeworm; hedatidosis; 'estomatitis'; distomatosi...

A. M. Tovar



Procedure de qualification des garnitures mecaniques des pompes principales des centrales nucleaires Francaises. (Mechanical seals qualification procedure of the main pumps of nuclear power plants in France).  

National Technical Information Service (NTIS)

Many important pumps in the nuclear power plants are equipped with mechanical seals. The good behaviour and reliability of mechanical seals depend specially on the quality and the stability of an interface of several microns. Peripheral speed reaches 50 m...

D. Buchdahl R. Martin J. M. Girault




Microsoft Academic Search

Resumen - En base a la necesidad de conocer si un evento extraordinario de lluvias en el acuífero de Irapuato Valle afectó la calidad del agua subterránea extraída, se realizó un análisis estadístico a través de pruebas no paramétricas de datos ordenados por rango y de nivel nominal de los parámetros físicos, químicos y bacteriológicos que determinan la calidad del

José de Jesús; Mora Rodríguez; Carlos Gutiérrez Ojeda; Luis González Hita


Sistemas de apareamiento en reptiles: una revisión  

Microsoft Academic Search

Mating systems in reptiles: a review. - Among vertebrates, reptiles are known to manifest a substan- tial variation of mating systems based on relatively complex social systems and different spatial organizations. The most frequent mating system is that situation where individuals of both sexes mated with more than one individual of the opposite sex. Monogamy (i.e. exclusive and long term



Sistemas Planetarios en Presencia de Júpiters Calientes  

NASA Astrophysics Data System (ADS)

In the present work we show results of N-body simulations aimed at analyzing the main dynamical aspects concerning the evolution of planetary embryos during the formation and evolution of a Hot Jupiter, for different values of the giant planet mass and the migration timescale. FULL TEXT IN SPANISH

de Elía, G. C.; Guilera, O. M.; Brunini, A.


Testing and evaluating virus detectors for handheld devices  

Microsoft Academic Search

The widespread use of personal digital assistants and smartphones gives securing these devices a high priority. Yet little attention has been placed on protecting handheld devices against viruses. Currently available antivirus software for handhelds is few in number. At this stage, the opportunity exists for the evaluation and improvement of current solutions. By pinpointing weaknesses in the current antivirus software,

Jose Andre Morales; Peter J. Clarke; Yi Deng; B. M. Golam Kibria



Embedded Malware Detection Using Markov n-Grams  

Microsoft Academic Search

Embedded malware is a recently discovered security threat that allows malcode to be hidden inside a benign file. It has been shown that embedded malware is not detected by commercial antivirus software even when the malware signature is present in the antivirus database. In this paper, we present a novel anomaly detection scheme to detect embedded malware. We first analyze

M. Zubair Shafiq; Syed Ali Khayam; Muddassar Farooq



Análise do desgAste produzido no prepAro de cAnAis rAdiculAres com o sistemA oscilAtório em três diferentes velocidAdes AnAly SiS Of the PROdUCed COnSUming in the ROOt CAnAlS PRePARAtiOn with the OSCillAt ORy Sy Stem in thRee diffeRent SPeedS  

Microsoft Academic Search

resumo Introdução: Este estudo avalia, in vitro, a quantidade de desgaste produzido por instrumentos endodônti- cos de aço inoxidável, acionados a um sistema automatizado de movimento oscilatório, em três diferentes velocidades: 6.000, 8.000 e 10.000 rotações por minuto. Métodos: Para isso, foram utilizadas 18 raízes palatinas de molares superiores, que foram distribuídas aleatoriamente em três grupos experimentais e individualmente pesadas

Orlando Limongi; Anelise Vieira Bernardes; Patrícia Rodriguez; Silveira Netto; Tiago André; Fontoura de Melo; Renata Grazziotin Soares


EL PROCESO DE BURNOUT Y EL VIH\\/SIDA: PRINCIPALES IMPLICACIONES EN LOS TRABAJADORES DE LA SALUD Burnout process and hiv\\/aids: main implications for health care workers  

Microsoft Academic Search

Burnout has been identified as a significant problem in health care professions, particularly for those working in chronic care. Occupational burnout is conceptualised as a particular type of stress occurring principally in professional contexts where work overload demands, especially those of an interpersonal nature, lead to chronic emotional exhaus- tion, depersonalization and reduced sense of personal ac- complishment explaining most

Velasco Furlong; Garrosa Hernández; Morante Benadero



¿Es un sistema financiero menos procíclico una meta alcanzable?  

Microsoft Academic Search

La banca y las finanzas son inherentemente procíclicas, una condición exacerbada por la combinación de Basilea II y la contabilidad a valor de mercado (mark-to-market accounting), por lo que se requiere crear políticas macroprudenciales anticíclicas. Esta fragilidad se vio intensificada por la reducción en la liquidez bancaria (mayor dependencia en fondos de segundo piso) y el cambio organizacional de sociedades

Charles Goodhart



Dinamica EGO, uma plataforma para modelagem de sistemas ambientais  

Microsoft Academic Search

Simulation models can be envisaged as a heuristic device useful for assessing, from long and short- terms, the outcomes from a variety of scenarios, translated as different socioeconomic, political, and environ- mental frameworks. A special class among them, spatially explicit models simulate the dynamics of an environ- mental system, reproducing the way its spatial patterns evolve, to project the probable

Hermann Oliveira Rodrigues; Britaldo Silveira Soares-Filho; William Leles de Souza Costa


The Mexican Sistema de Alerta Sismica (SAS) Experience  

Microsoft Academic Search

The Mexico City's SAS is an Early Warning System developed in accordance with recommendations of foreign and national seismology experts, after the disaster generated in 1985 by the M8.1 Michoacan earthquake. The SAS aim is to help mitigate future seismic disasters in Mexico City (MC), mainly if the big forecast \\

J. Espinosa-Aranda; F. Rodriguez



Sistema de Liberación de Lotes del CBER: Resumen del ...  

Center for Biologics Evaluation and Research (CBER)

Text Version... Una de las cosas que suelen surgir, especialmente cuando se lidia con las pandemias de H5N1 y H1N1: ¿existe alguna forma para que diferentes ... More results from



Microsoft Academic Search

This article is divided into three seclions. The first part presents a description of a project of investigation about the efects of frustration and euphoria in the irnmune system, social and maternal behaviorin rats, and the rol of context in these effects. The second part describes the main results of the effects of consumatory succesive negative.and posilive contrast (CSNCand csrc)



Microrganismos do solo produtores de fosfatases em diferentes sistemas agrícolas  

Microsoft Academic Search

RESUMO Considerando-se que uma forma de prover fosfato disponível para as plantas é através da atividade mineralizadora microbiana do fósforo orgânico, avaliou-se a influência da planta (braquiária, guandu e sem planta), dos fertilizantes (superfosfato simples, fosfato de rocha e sem adubo) e da calagem (com e sem calcário) nas populações de microrganismos produtores de fosfatases ácida e alcalina. Do total

Ely Nahas



The Mexican Sistema de Alerta Sismica (SAS) Experience  

NASA Astrophysics Data System (ADS)

The Mexico City's SAS is an Early Warning System developed in accordance with recommendations of foreign and national seismology experts, after the disaster generated in 1985 by the M8.1 Michoacan earthquake. The SAS aim is to help mitigate future seismic disasters in Mexico City (MC), mainly if the big forecast "Guerrero Earthquake" hits. In 1991 the SAS started its service in an experimental basis for evaluating its performance both with a group of basic education students in public schools, and with the emergency stop function for the Mexico City Metropolitan Subway System (METRO of MC); after this The Federal District Government (FDG) opened the SAS as a public service in August, 1993, shortly after the SAS warned, with more than 60 seconds of anticipation, the incoming effect of May 13, 1993, M5.8, and M6 double earthquake originated more than 300 Km from MC between Guerrero and Oaxaca, on the coast. That year, an initial technical flaw generated one false alert signal; the cause was readily corrected. The SAS has 12 seismic sensor stations covering a stripe close to 400 X 100 Km on the Guerrero's coast, between Papanoa and Punta Maldonado, that send information through a dedicated radio relay system to the SAS Central Control in MC., using the valuable support of some TELMEX field installations. Until August, 2003, the SAS sensor system has detected more than 1550 earthquakes in the 2.55 magnitude events, which are the ones felt in MC. The SAS has generated 57 warning signals with an average of 60 sec in advance to earthquake effects: 46 of restricted use for M<6, and 11 of public use for M>6 events. Public warnings have the automatic broadcast support of many commercial radio AM/FM and TV stations in Mexico City and Toluca valleys. The FDG controls the SAS signal service that includes the more frequent events (from M>5 up), asking the user to develop procedures and practice useful actions to mitigate seismic disasters. Each validated SAS seismic warning automatically generates and sends the event information by fax and e-mail to the DFG and Civil Protection Authorities, users and news media; it also sends information about the SAS operating conditions to service technicians, via radio, and phone.

Espinosa-Aranda, J.; Rodriguez, F.



Sensoriamento Remoto de Sistemas Aquaticos (Remote Sensing of Aquatic System).  

National Technical Information Service (NTIS)

This is the first technical report of the 'Remote Sensing of the Aquatic Systems' Project sent to the 'Fundasao de Amparo a Pesquisa do Estado de Sao Paulo' describing the activities performed between May 1989 and June 1990. The methodology and technical ...

E. M. Leaodemoraesnovo C. Z. F. Braga



Evolución de estrellas que pertenecen a sistemas binarios cerrados  

NASA Astrophysics Data System (ADS)

Stellar evolution in close binary systems (CBSs, those in which one or more mass transfer/mass loss episodes can occur) is a topic of great interest in Astronomy. The reason is that a large fraction of the stars belong to CBSs and this has originated our interest for the study of such systems. Based on the stellar evolution code for isolated stars developed in the Facultad de Ciencias Astronómicas y Geofísicas (UNLP) by Dr. O.G. Benvenuto, we have built a new code that can compute the evolution of stars members of CBSs. The version of the code we have employed in performing the calculations we show in this work, make a great advance in the study of this kind of systems, since the rate of mass loss is computed in an self-consistent fashion. For this purpose, we have incorporated in the code for isolated stars a new variable in the iterations: the rate of mass loss dot{M}. In addition, we need to compute a critical radius that discern if the star is lossing mass or not. Based on the experience of other authors we have defined the radius of the Roche lobe as a critical radius in such a way that if the stellar radius overflows this, mass loss will occur. On the other hand, if the stellar radius is smaller, the evolution proceeds as if the star were isolated. If all mass lost from a star is deposited on the surface of its companion, and total systemic energy is conserved we have a conservative case. However, we have included in our code effects of energy loss for ejection of matter from the system, and consider dissipative effects like gravitational radiation and magnetic braking. This considerations causes different results from conservative case. Inasmuch as, in view of the non conservation of total angular momentum, it is necessary to perform a careful calculation of the orbital evolution. We present the evolution of four primary stars (the initially more massive star in the systems) with the following characteristics: - Initial masses of 1.5 and 2 M?, initial period of 0.7 days, and initial mass ratio of 1.5. Case A (mass transfer begin during core hydrogen burning), non conservative. - Initial masses of 2 and 1.4 M?, initials periods of 1.5 and 1 days, initial mass ratios of 1.5 and 1, respectively. Case B (mass transfer begin during central contraction after central hydrogen exhaustion), non conservative. We have also shown the results obtained with a version of the code, in preparation, that performs the evolution for both stars belonging to a CBS simultaneously. It is a CBS in which the initial mass of the primary is 10 M?, the initial period of 6 days and the initial mass ratio of 1.25. Case B, conservative.

De Vito, M. A.; Benvenuto, O. G.



Microsoft Academic Search

Nitrogen in dairy farm systems. Nitrogen is a very important element for all living organisms. It is present in the atmosphere, soil and water. It is applied all over the world to produce food. Nitrogen for agriculture can be supplied by inorganic fertilizer, bacterial fixation, animal manure, crop residues, and mineralization. Currently, nitrogen fertilizer is the major source of nitrogen

Jorge Elizondo Salazar




Microsoft Academic Search

This paper is about artificial intelligence in Medicine. Here, it tries to describe all the technologies' implications in this area. It is really important to realize the changes that the world is suffering with the computational evolution, more, if it is talking about healthcare. Soon, people will count with a lot of artificial intelligence applications in medicine which could help



Contribución de la Estación San Juan SLR al Sistema Galileo  

Microsoft Academic Search

The new San Juan Satellite Laser Ranging Station integrates, with number 7406, the International Laser Ranging Service (ILRS) network, being one of the few stations located in the southern hemisphere. It works shooting powerful laser pulses towards satellites at different heights, measuring the time of flight and calculating distances. With this technology we can perform high precision astronomical, geophysical and

R. Podestá; E. Actis; E. Alonso; A. Pacheco; A. González; Yanben Han; Tanqiang Wang; Limin Zhao; Chengzhi Liu; J. Alacoria; L. Peñaloza; D. Brizuela; M. Flores



Sistema de Labranza y Productividad de los Suelos  

Microsoft Academic Search

In this Chapter we discuss the effect of tillage on the physical, chemical and biological properties of the soil.The intensification of agriculture using traditional crop tillage practices involving the inversion of the upper soil layer, decreases de soil organic matter content. No-tillage practices, leaving the crop residues on top of the soil, increase the soil organic matter content positively affecting



Diversidad de Sistemas Planetarios en Discos de Baja Masa  

NASA Astrophysics Data System (ADS)

The accretion process that allows the formation of terrestrial planets is strongly dependent on the mass distribution in the system and the presence of gas giant planets. Several studies suggest that planetary systems formed only by terrestrial planets are the most common in the Universe. In this work we study the diversity of planetary systems that could form around solar-type stars in low mass disks in absence of gas giants planets and search wich ones are targets of particular interest. FULL TEXT IN SPANISH

Ronco, M. P.; de Elía, G. C.


Ferramenta para teste de projetos de sistemas embutidos  

Microsoft Academic Search

Verification of embedded system designs is a major challenge. The hand generation of test scenarios for embedded system is a time consuming and error prone task. This paper presents an automatic test environment generation that includes test scenarios generation, guided by a system-level SpecC description of a design, and verification, based on a requirements specification written in the formal quantitative

Caixa Postal


IV. Presentación de Proceso para Sistemas en Envasado ...  

Center for Food Safety and Applied Nutrition (CFSAN)

... Asigne un de SID único para cada formulario de presentación de proceso, en el formato YY-MM-DD/SSS basado en la fecha en que presenta el ... More results from


Los Pigmentos Vegetales y la Fotosíntesis  

NSDL National Science Digital Library

En esta lección se examinarán las dos principales clases de pigmentos fotosintéticos: las clorofilas y los carotenoides. Se analizarán sus estructuras bioquímicas y su biosíntesis, y se explicará además la organización de estos pigmentos en los sistemas fotosintéticos, que son complejos proteicos que colectan y convierten la energía luminosa en energía química.


Sistemas de lógica difusa en el proceso de secado Sistemas de lógica difusa en el proceso de secado Sistemas de lógica difusa en el proceso de secado Sistemas de lógica difusa en el proceso de secado Sistemas de lógica difusa en el proceso de secado de café en lecho fluidizado  

Microsoft Academic Search

The present investigation deals with a system for coffee bean drying on a fluidised bed. A prototype was used in which coffee beans were dried using several drying temperatures. The results showed 6 to 8 hour drying periods. The coffee beans presented uniform final humidity content and the product presented good sensory characteristics. Complementing the foregoing and considering this process'

Elkin Mauricio; López Fontal



Architectural Support for Run-Time Validation of Program Data Properties  

Microsoft Academic Search

As computer systems penetrate deeper into our lives and handle private data, safety-critical applications, and transactions of high monetary value, efforts to breach their security also assume significant dimensions way beyond an amateur hacker's play. Until now, security was always an afterthought. This is evident in regular updates to antivirus software, patches issued by vendors after software bugs are discovered,

Divya Arora; Srivaths Ravi; Anand Raghunathan; Niraj K. Jha



RiskRanker: scalable and accurate zero-day android malware detection  

Microsoft Academic Search

Smartphone sales have recently experienced explosive growth. Their popularity also encourages malware authors to penetrate various mobile marketplaces with malicious applications (or apps). These malicious apps hide in the sheer number of other normal apps, which makes their detection challenging. Existing mobile anti-virus software are inadequate in their reactive nature by relying on known malware samples for signature extraction. In

Michael Grace; Yajin Zhou; Qiang Zhang; Shihong Zou; Xuxian Jiang



The effectiveness of vaccinations on the spread of email-borne computer viruses  

Microsoft Academic Search

In the last decade, computer viruses have caused tremendous losses to organizations. New viruses continue to cause havoc, in spite of having better antivirus software. It is thus imperative that we understand what factors significantly influence the spread of viruses. In this paper, we model the networks of users as graphs. For simplicity, we assume that every user works only

S. Data; Hui Wang



Server-side dynamic code analysis  

Microsoft Academic Search

The common use of packers is a real challenge for the anti-virus community. Indeed, a static signature analysis can usually only detect and sometimes remove known packers if a specific unpacking routine has been programmed manually. Generic unpacking does not solve the problem due to its limited effectiveness. Additionally, the important number of binaries to scan on a daily basis

Wadie Guizani; Jean-Yves Marion; Daniel Reynaud-Plantey



Large-scale malware indexing using function-call graphs  

Microsoft Academic Search

A major challenge of the anti-virus (AV) industry is how to ef- fectively process the huge influx of malware samples they receive every day. One possible solution to this problem is to quickly de- termine if a new malware sample is similar to any previously-seen malware program. In thispaper, we design, implement and evaluate a malware database management system called

Xin Hu; Tzi-cker Chiueh; Kang G. Shin



MalTRAK: Tracking and Eliminating Unknown Malware  

Microsoft Academic Search

Malware or malicious code is a rapidly evolving threat to the computing community. Zero-day malware are exploiting vulnerabilities very soon after being discovered and are spreading quickly. However, anti-virus tools, which are the most widely used countering mechanism, are unable to cope with this. They are based on signatures which need to be computed for new malware strains. After a

Amit Vasudevan



Computer Forensics Investigations in a Corporate Environment  

Microsoft Academic Search

Most organizations today accept that it is a fundamental business requirement to protect electronic information assets, and are implementing an increasing number of information security counter_measures, such as intrusion detection systems (IDS), access control mechanisms, and anti_virus products to protect their IT systems from potential security threats.

Deniz Sinangin



Help for the Help Desk: School District Technology Managers Learn to Do with Less.  

ERIC Educational Resources Information Center

Although the E-Rate has been a catalyst for school technology purchases, there are no subsidies for hiring qualified technology support staff. District technology coordinators are relying on technology support systems and shoestring survival strategies, employing standardized equipment and hard-drive configurations, desktop lockdowns, anti-virus

Kongshem, Lars



Virus Alert: Ten Steps to Safe Computing.  

ERIC Educational Resources Information Center

Discusses computer viruses and explains how to detect them; discusses virus protection and the need to update antivirus software; and offers 10 safe computing tips, including scanning floppy disks and commercial software, how to safely download files from the Internet, avoiding pirated software copies, and backing up files. (LRW)

Gunter, Glenda A.



Biologically Inspired Defenses Against Computer Viruses  

Microsoft Academic Search

Today's anti-virus technology, based largely on analysis of existing viruses by human experts, is just barely able to keep pace with the more than three new computer viruses that are writ­ ten daily. In a few years, intelligent agents nav­ igating through highly connected networks are likely to form an extremely fertile medium for a new breed of viruses. At

Jeffrey O. Kephart; Gregory B. Sorkin; William C. Arnold; David M. Chess; Gerald Tesauro; Steve R. White



Design of RFID Slot Tag Antenna for Metal Containers  

Microsoft Academic Search

Worm propagation model is an important issue in network information security. Based on the knowledge of infectious disease dynamics, the major methods to research worm propagation are related to some characteristics of network, such as topology, traffic, user behavior. In 2008, with the transformation of key antivirus work from the terminal PC to network server group, the industry put forward

Yanmei Zhang; Hongjin Wang



An artificial immune system architecture for computer security applications  

Microsoft Academic Search

With increased global interconnectivity, reliance on e-commerce, network services, and Internet communication, computer security has become a necessity. Organizations must protect their systems from intrusion and computer-virus attacks. Such protection must detect anomalous patterns by exploiting known signatures while monitoring normal computer programs and network usage for abnormalities. Current antivirus and net- work intrusion detection (ID) solutions can become overwhelmed

Paul K. Harmer; Paul D. Williams; Gregg H. Gunsch; Gary B. Lamont



Collective Defense: Applying the Public-Health Model to the Internet  

Microsoft Academic Search

Governments, enterprises, and consumers face myriad technically advanced and persistent computer threats. Commonly available cyberdefenses such as firewalls, antivirus software, and automatic updates for security patches help reduce the risk from threats. However, they're inadequate because many consumers sometimes ignore the guidance provided or engage in other unsafe actions (such as downloading executable programs from unknown sources). Those with infected

Scott Charney



IT Security Strategies for SME's  

Microsoft Academic Search

Small and medium enterprises (SMEs) is leaning more on their information technology (IT) infrastructure but they lack the means to secure it appropriately due to financial restrictions, limited resources, and adequate know-how. Many SME managers believe that IT security in their company is basically equivalent to having a firewall and updating the antivirus software regularly. Strategic policies, information theft, business

Ji-Yeu Park; Rosslin John Robles; Chang-Hwa Hong; Sang-Soo Yeo; Tai-hoon Kim



How Much Security Does Your Library Need?  

ERIC Educational Resources Information Center

|Explains how to keep library systems healthy and functioning by taking sensible security measures. Examines why hackers would target library systems and how library systems are compromised. Describes tools that can help, including: firewalls; antivirus software; alarms; network analysis tools; and encryption. Identifies several strategies for…

Banerjee, Kyle



Peace (of Mind) in Our Time  

ERIC Educational Resources Information Center

|There's no silver bullet to information security; universities must continue to keep their antivirus, anti-spyware, firewall, and patch management systems in good working order. These days, the largest target for hackers appears to be university databases. Now, universities are searching for new solutions to safeguard those systems. This article…

Panettieri, Joseph C.



Computer viruses: ways of reproduction in MS-DOS  

Microsoft Academic Search

The methods used by computer viruses to reproduce themselves in IBM PC-compatibles operating under MS-DOS are studied. The results can be of use for classification of viruses and the creation of anti-virus tools. Viruses are examined under the following headings: irritating viruses, viruses that damage files, viruses that damage the file system and viruses that injure the hardware

S. I. Shoutkov; A. V. Spesivtsev



Using Code Normalization for Fighting Self-Mutating Malware  

Microsoft Academic Search

Self mutating malware has been introduced by computer virus writers who, in '90s, started to write polymorphic and metamorphic viruses in order to defeat anti-virus products. In this paper we present a novel approach for dealing with self mutating code which could represent the basis for a new detection strategy for this type of malware. A tool prototype has been

Danilo Bruschi; Lorenzo Martignoni; Mattia Monga



Towards Stealthy Malware Detection  

Microsoft Academic Search

Malcode can be easily hidden in document files and go undetected by standard technology. We demonstrate this opportunity of stealthy malcode insertion in several experiments using a standard COTS Anti-Virus (AV) scanner. Furthermore, in the case ofzero-daymalicious exploit code, signature- based AV scanners would fail to detect such malcode even if the scanner knew where to look. We propose the

Salvatore J. Stolfo; Ke Wang; Wei-Jen Li


Variant Rabbit Hemorrhagic Disease Virus in Young Rabbits, Spain  

PubMed Central

Outbreaks of rabbit hemorrhagic disease have occurred recently in young rabbits on farms on the Iberian Peninsula where rabbits were previously vaccinated. Investigation identified a rabbit hemorrhagic disease virus variant genetically related to apathogenic rabbit caliciviruses. Improved antivirus strategies are needed to slow the spread of this pathogen.

Dalton, Kevin P.; Nicieza, Ines; Balseiro, Ana; Muguerza, Maria A.; Rosell, Joan M.; Casais, Rosa; Alvarez, Angel L.



A Mission-Impact-Based Approach to INFOSEC Alarm Correlation  

Microsoft Academic Search

We describe a mission-impact-based approach to the analysis of security alerts produced by spatially distributed heterogeneous information security (INFOSEC) devices, such as firewalls, intrusion detection systems, authentication services, and antivirus software. The intent of this work is to deliver an automated capa- bility to reduce the time and cost of managing multiple INFOSEC devices through a strategy of topology analysis,

Phillip A. Porras; Martin W. Fong; Alfonso Valdes



Variant rabbit hemorrhagic disease virus in young rabbits, Spain.  


Outbreaks of rabbit hemorrhagic disease have occurred recently in young rabbits on farms on the Iberian Peninsula where rabbits were previously vaccinated. Investigation identified a rabbit hemorrhagic disease virus variant genetically related to apathogenic rabbit caliciviruses. Improved antivirus strategies are needed to slow the spread of this pathogen. PMID:23171812

Dalton, Kevin P; Nicieza, Inés; Balseiro, Ana; Muguerza, María A; Rosell, Joan M; Casais, Rosa; Álvarez, Ángel L; Parra, Francisco



Research of intelligent immune intrusion detection system about combating virus with “virus”  

Microsoft Academic Search

To solve the limitation problems exist in the anti-virus software, firewall, intrusion detection system, intrusion defense system and vulnerability scanning system, the research of the active defense system is imperative. This paper cited the feasibility and necessity of combating virus with \\

Zhou Shao-jing; Shao Wen-li; Rong Hui; Chen Zhen-ting; Yang Yu



Biological activities and corresponding SARs of andrographolide and its derivatives.  


In recent years, pharmaceutical chemists have synthesized large numbers of andrographolide derivatives, which bear important biological activities such as anti-inflammatory, antibacterial, antivirus, antitumor, antidiabetic, and antifeedant. Consequently, corresponding SARs were increasingly obvious. This paper aimed to review all the available literature in this field, highlighting the significant achievements on the structural modification and SARs of andrographolide and its derivatives. PMID:23438057

Zhou, Bin; Zhang, Dayong; Wu, Xiaoming



Lock It Up! Computer Security.  

ERIC Educational Resources Information Center

|The data contained on desktop computer systems and networks pose security issues for virtually every district. Sensitive information can be protected by educating users, altering the physical layout, using password protection, designating access levels, backing up data, reformatting floppy disks, using antivirus software, and installing…

Wodarz, Nan



A Comparative Study on Marketing Mix Models for Digital Products  

Microsoft Academic Search

The rise of the Internet and electronic commerce provide a huge marketspace and unique transaction process for digital products. It is signiflcant to discuss whether established marketing models can be revised for digital products. First, the unique features of digital products are systematically reviewed, and then three typical digital products, in- cluding e-books, anti-virus, and online translation services, are analyzed

Kanliang Wang; Yuan Wang; Jingtao Yao




Microsoft Academic Search

Soil conservation practices in maize-bean production systems in Cuba. Two trials were conducted in production conditions in watersheds of the Pinar del Río province, one in Campo Hermoso and the other in La Comunidad La Leña, Cuba. At both sites, rotations were conducted involving two bean varieties: BAT 304 and Tomeguin 93, followed by maize associated with Mucuna deeringianum. Border

Claro A. Alfonso; Mario Riverol; Pedro Porras; Eduardo Cabrera; Milagros Monedero



Microsoft Academic Search

This work was developed aiming at evaluati ng the strands alignement system for OSB panels production (oriented strand board). A mat forming box was designed and built to evaluate the efficiency of the alignement system by testing static bending in the aligned and cross directions to the panel axis . Pinus taeda wood was used for stranding, and later on,

Lourival Marin Mendes; Setsuo Iwakiri; Jorge Luis; Monteiro de Matos; Sidon Keinert Jr; Leopoldo Karman



Microsoft Academic Search

En la enseñanza del Derecho cobra vida un grupo de categorías didácticas, aplicadas al desarrollo sistémico del proceso docente-educativo, que constituyen la base donde se sostiene una parte importante de la teoría pedagógica. Entre estas categorías se encuentran las formas organizativas y la evaluación del aprendizaje, las que poseen un carácter universal, a partir de su expresión en los distintos

Carlos Justo Bruzón Viltres



ECIS - Adaptacao para o sistema CDC CYBER. (ECIS - Adaptation to CDC CYBER system).  

National Technical Information Service (NTIS)

The implantation of ECIS computer code, elaborated for BOURROUGHS 6700 computer of USP (Universidade de Sao Paulo), in the CDC CYBER 170/730 computer is presented. The ECIS code calculates cross section by coupled channel method. Some problems were calcul...

R. P. K. Nair R. A. Rego B. J. K. Lemos



Análise da contaminação dos sistemas hídricos por agrotóxicos numa pequena comunidade rural do Sudeste do Brasil  

Microsoft Academic Search

Recent advances in analytical techniques allow identifying pesticide pollution in water systems. In small rural communities, the negative effects of pesticide pollution can be aggravated by the lack of infrastructure and adverse socioeconom- ic conditions. This study investigated pesticide pollution in potential water supply sources in a tomato growing area in Paty do Alferes, Rio de Janeiro State, Brazil. The

Marcelo Motta Veiga; Dalton Marcondes Silva; Lilian Bechara Elabras Veiga; Mauro Velho de Castro Faria



Modelagem matemática de sistemas de ozonização de contato - Parte I : Formulação Teórica  

Microsoft Academic Search

Efficient ozonation in water and wastewater treatment processes requires a contact system with high transfer efficiency since: (a) ozone gas is not very soluble in water; (b) it is highly desirable to optimize the ozone transfer from gas phase into the liquid phase. Regarding ozone transfer, co-current and counter-current contactors are the most widely utilized ozone transfer systems. This text

Sérgio Eiger; Frederico Almeida; Lage Filho


Modelagem matemática de sistemas de ozonização de contato - Parte II : Exemplos de Aplicação  

Microsoft Academic Search

A deterministic mathematical model was derived and applied to several simulations of an ozone contactor composed by four columns in series which behaved as plug-flow reactors, with the first one receiving raw water. Such model was derived from the exact analytical solution of a differential equation system describing ozone mass transfer in a liquid-gas system. Such analytical solution approach is

Frederico de Almeida; Lage Filho; Sérgio Eiger


Stsintillyatsionnaya triggernaya sistema zhidkoargonovogo nejtrinnogo detektora. (Scintillation trigger system of the liquid argon neutrino detector).  

National Technical Information Service (NTIS)

This paper presents the organization of the Scintillation Trigger System (STS) for the Liquid Argon Neutrino Detector of the Tagged Neutrino Facility. STS is aimed at the effective registration of the needed neutrino interaction type and production of a f...

S. V. Belikov S. N. Gurzhiev Y. Gutnikov A. G. Denisov V. I. Kochetkov



Sirius: Sistema de Pesquisa E Recuperacao Bibliografica (Sirius: Bibliographic Search and Retrieval System).  

National Technical Information Service (NTIS)

An on-line system developed and implemented at INPE may be accessed to obtain bibliographic data through the arguments such as author, title, descriptor and series; as well as to obtain up-dated circulation information about a certain material and/or user...

E. F. Doofilho U. M. Defreitas V. L. Siqueira C. R. T. Dasilva M. L. Ribeiro



Aplicaciones del sistema GPS en la búsqueda de sitios para Interferometría Astronómica Milimétrica  

NASA Astrophysics Data System (ADS)

The water vapor content of the atmosphere is the biggest restriction to the Millimeter and Sub-millimeter Astronomy. It also plays a crucial role in most of the atmospheric processes. Nowadays water vapor is one of the less characterized meteorological parameter. It is a highly variable atmospheric constituent and its presence is a limiting factor to the obtention of high angular resolutions in interferometric observations of astrophysical interest. Thus, the improved determination of the percentage of precipitable water vapor (PWV) is widely appreciated when performing a site testing for Millimeter Astronomy (MA). It is extensive the use of Water Vapor Radiometers (WVRs) for characterizing the PWV. Using its typical frequency the WVR monitors at 22 Ghz., but some of them had been specially designed for MA at 183 Ghz (M.C. Wiedner, Atmospheric Water Vapour and Astronomical Millimetre Interferometry, PhD Thesis, 1998). Another possibility for PWV determinations are the Radiosondes (RS). A RS is a nothing but a set of sensors and radio transmitters carried out by a balloon up to 30.000 mts. They register twice a day (at 0 UTC and 12 UTC) the values of temperature, humidity and atmospheric pressure as a function of the altitude. All the observations are immediately transmitted to a ground station. At the beginning of the '90s GPS started to be used as an approach to the remote sensing of atmospheric water vapor (Bevis et al, Geophys. Res., 97, 15787, 1992). The radio signal GPS is delayed by the atmosphere as it propagate from the satellites to the ground-receivers. The tropospheric delay is modeled as the add of two contributions: a ``dry" and a ``wet" delay. Each of them is calculated as the product of a zenith path delay by a mapping function depending on the elevation angle. An estimate of the zenith wet delay can be transformed into an estimate of the PWV (Bevis et al, 1992; Hogg et al., A&A, 95, 304, 1981). Any of the former techniques can determine the PWV with an accuracy better than 1 millimeter of PWV. In this work we use the GPS to estimate the PWV. The procedure followed here is having comparable precision and accuracy with respect to the classical techniques (Coster et al., GPS-96, 625, 1996).

Meza, A.; Fernández, L.; Natali, P.; Moirano, J.; Brunini, C.


La producción de cráteres en el Sistema de Satélites de Saturno  

NASA Astrophysics Data System (ADS)

The saturnian satellite system has been observed by the Cassini-Huygens mission, in particular the impact craters on them. These satellites present a diversity of surfaces which could help us to understand about their history. To study the production of craters on these satellites, we develop a theoretical model from previous simulations and we obtain the contribution of Centaur objects to the production of craters. We calculate the number of craters for a given size and the greatest crater produced by Centaur objects. This allowed us to compare our theoretical results with the observations by the Cassini-Huygens and determine the origin of craters as well as constrain the size distribution of Centaurs. FULL TEXT IN SPANISH

Zanardi, M.; Di Sisto, R. P.


Interacciones de galaxias: sistemas co-rotantes y contra-rotantes  

NASA Astrophysics Data System (ADS)

In this paper we present a sample of interacting galaxy pairs with tidal tails. We perform a visual cassification according to the sense of rotation of the spiral arms of each member of the tidal system. We study general features of interacting galaxies such as mass content in stars (M^*), luminosity ratios and local environment through an analysis of the ?_5 parameter. FULL TEXT IN SPANISH

Mesa, V.; Duplancic, F.; Alonso, S.; García Lambas, D.


Modelos autoconsistentes de sistemas estelares cuspidales y triaxiales con distribución de velocidades casi isotrópica  

NASA Astrophysics Data System (ADS)

It has been shown in many works that it is possible to build stable, self-consistent models of triaxial stellar systems, even with cusps, and containing high percentages of chaotic orbits. Since all these models have been obtained from cold collapses, their velocity distributions are strongly radial. Also, chaos was computed using either Lyapunov exponents or SALI. However, models obtained by adiabatic deformation of spherical systems, in which the velocity distribution is more isotropic, showed a very low level of chaos, though it must be noted that the method of detecting chaos used in this case, namely the variation of orbital frequencies, is less sensitive than the abovementioned methods. In this work, we present models obtained by adiabatic deformation, in which we compute the fraction of chaotic orbits using both Lyapunov exponents and variation of orbital frequencies. Our results show that the percentages of chaotic orbits is significant, though they are smaller than those obtained in models with strong radial velocity components. FULL TEXT IN SPANISH

Carpintero, D. D.; Muzzio, J. C.; Navone, H. D.; Zorzi, A. F.


Sistema di Sorveglianza OKkio alla SALUTE: Risultati 2010. (Surveillance System of OKkio alla Salute: Results 2010.)  

National Technical Information Service (NTIS)

In 2007 the Italian Ministry of Health promoted OKkio alla SALUTE, national nutritional surveillance system based on biannual cross-sectional surveys and coordinated by the National Institute of Health. It aims to estimate the prevalence of overweight and...

A. Lamberti A. Spinelli D. Galeone P. Nardone S. Andreozzi



Sistema Solar: de la observación de La Tierra a los planetas gigantes y sus lunas  

NASA Astrophysics Data System (ADS)

La fotoquímica tiene un papel principal en la composición de las atmósferas planetarias. Se examinan diferentes procesos fotoquímicos tanto para atmósferas oxidadas como reductoras, poniendo un especial énfasis en los ciclos químicos más importantes. En este sentido, se presentan diferentes ciclos químicos capaces de producir hidrocarbonos y nitrilos en atmósferas reductoras, así como aquellos capaces de mantener las proporciones de mezcla de las moléculas que contienen oxígeno, tales como CO2, O2 y H2O. También se analizan otros procesos importantes tales como la condensación y procesos de sputtering y de sublimación que han de tenerse en cuenta cuando se realizan modelos sobre la composición atmosférica.

Rodrigo, R.


SISTEMA INMUNE Y VACUNACIÓN DE PECES Immune System And Vaccination In Fish  

Microsoft Academic Search

The fish immune system posses many of the cells and molecules found in higher vertebrates, but several other components and functions such as the melano- macrophage centers and the phagocityc activity of the epithelial enteric cells which are not found in higher vertebrates are described in fish, though their function is poorly understood. In adition, the aquatic environment, and even



El sistema inmune de los invertebrados - The immune system of the invertebrates)  

Microsoft Academic Search

The immune recognition and physiological mechanisms related with immune system were evolutionary selected to maintain the viable organisms. On the other hand, survive of the organisms, both vertebrate and invertebrates, and their evolution depends of defense mechanisms that helped adapting to different habitats. An efficient immune system was developing in the invertebrates, it has

Antón Marín


Acuabio 1, un estimulador del sistema inmune de camarones Litopenaeus vannamei  

Microsoft Academic Search

Acuabio 1, an enhancer of the immune system in Litopennaeus vannamei shrimps. Acuabio 1 is a mixture of proteins and essential amino acids that exerts a stimulating effect in the development of aquatic organisms. It synchronizes and accelerates fish and shrimp larvae growth on early developmental stages, as well as increases the development and size of these animals. In this

Ramón Franco; Amilcar Arenal; Leonardo Martín; Dayamí Santiesteban; Jorge Sotolongo; Rebeca Martínez; Mario P Estrada


El género Brucella y su interacción con el sistema mononuclear fagocítico  

Microsoft Academic Search

Non-specific resistance is a fundamental component of the host immune response. The mononuclear phagocytic system (MPS) is part of innate resistance effector mechanisms, and is involved in several homeostatic, inflammatory and immunologic events. Mononuclear phagocytes (MNP), which are cells belonging to the MPS, play a central role in the main functions of multicellular organisms. Its early interaction with pathogens determines

Mirta B. Aréstegui; Javier Domínguez



Las Células Dendríticas y su Papel de Centinelas del Sistema Inmune  

Microsoft Academic Search

La historia natural de estas células se divide en dos: células inmaduras y células maduras. Las CDe inmadu- ras se encuentran distribuidas ampliamente en tejidos linfoides y no linfoides y con una tasa de recambio rela- tivamente rápida (vida media menos de dos días). Esta alta tasa de recambio está asociada a una de las carac- terísticas particulares de esta

Melitza Iglesias



Microsoft Academic Search

MATERNAL EFFECTS AND IMMUNE RESPONSE. STUDIES IN THE ENDEMIC CHAGAS' DISEASE Pregnancy in mammals results from the coexistence during gestation of two organisms that constantly interact through various stimuli, namely, the antigenic ones. The young are submitted to the influences of the maternal environment, notably nutritional and immunological, during gestation and in the first stages of intrauterine life. For this




On Modelling an Immune System Sobre un Modelo Computacional del Sistema Inmune  

Microsoft Academic Search

Immune systems of live forms have been an abundant source of inspiration to contemporary computer scientists. Problem solving strategies, stemming from known immune system phenomena, have been successfully applied to challenging problems of modern computing. However, research in artificial immune systems has overlooked establishing a coherent model of known immune system behaviour. This paper aims reports on an preliminary computer

Raúl Monroy; Rosa Saab; Fernando Godínez; Eugenio Garza Sada; Nuevo León



Sueño y Sistema Inmune: Diferencias en Variables Inmunológicas en Sujetos con Apnea y Controles  

Microsoft Academic Search

Recently, interest for studying the relationship between sleep and immunological system has increased. The Obstructive Sleep Apnea Syndrome (OSAS) is a disorder characterized by repetitive episodes of respiratory cessation that occur during sleep. Recent studies have suggested the need to study the relation between OSAS and immune system. The objective of this study was to analyze the differences between subjects

Pablo Vera-Villarroel; Ana I. Sánchez; Gualberto Buela-Casal



Topologia Hídrica: uma proposta para gestão de recursos hídricos utilizando sistema de informações geográficas  

Microsoft Academic Search

The National Water Resource Information System (SNIRH) is a management instrument defined by the Brazilian Federal Law 9.433 (08 of January of 1997). Since 2004, the SNIRH has been developed by the National Water Agency (ANA). The module of the SNIRH known as \\

Marco Antônio Silva; Morris Scherer-Warren; Regiane Maria; Paes Ribeiro; Hauschild Fernando; Maciel Lima; Campos Neto; Agência Nacional de Águas


jXChat - Um Sistema de Comunicação Eletrônica Inteligente para apoio a Educação a Distância  

Microsoft Academic Search

Synchronous communication tools are possible options for communication in distance learning environment. However, management of student's discussion and participation in these k ind o f t ool i s a ha rd task from the teacher point of view. This work proposes a model of a electronic communication system. Actually the system is a synchronous communication tool, usually called chat,

Francisco José Martins; Débora Nice Ferrari; Cláudio F. R. Geyer


Emisión H? en sistemas binarios cromosféricamente activos (RS CVn y BY Dra)  

NASA Astrophysics Data System (ADS)

We report here high and medium resolution Balmer H? line profiles for 11 chromospherically active binary systems including the class of RS Canum Venaticorum binaries (RS CVn) and BY Draconis (BY Dra) with a total range of rotation periods from 0.8 to 24 days. We have obtained different types of H? line profiles: strong emission line, weak emission line with strong superposed absorption profile and filled-in absorption line profile. We have measured the H? equivalent width of the program stars and the H? core emission was determined by subtraction of the equivalent width of a presumably inactive star with the same spectral type and luminosity class.

Fernández-Figueroa, M. J.; Montes, D.; de Castro, E.



Il Nuovo Sistema Informativo Sanitario (Nsis): modello concettuale di base Dicembre 2005  

Microsoft Academic Search

Il Servizio Sanitario Nazionale si colloca in uno scenario politico e sociale in profonda evoluzione, per effetto del progressivo decentramento di poteri e competenze dallo Stato alle Regioni e della necessità di garantire un maggiore equilibrio tra le risorse da destinare all'acuzie e alla cronicità. In questo contesto è emersa la necessità di costruire una base dati nazionale, condivisa con

Daniela Canali; Marta Fantola CNR-Istituto; Tecnologie Biomediche



Microsoft Academic Search

In a plane typical structure, many elements are geometrically identical: wings, vertical tail plane, flaps, ailerons, etc, adapting the supporter profile form, so studied in the aerodynamics. It is from this perception that the idea of automating its design emerges. This work, resulting from the collaboration with the CAD-CAM department in EADS-CASA, aims to go a step further, taking advantage



Vakuumnaya sistema mass-spektrometra LIDIA. (Vacuum system of the mass spectrometer LIDIA).  

National Technical Information Service (NTIS)

The high vacuum system of the mass spectrometer LIDIA is described and its parameters are presented. The construction is complitely based on the superhigh vacuum technology. It is shown that the pressure in the internal volume 3x10(sup -6) Pa can be easil...

D. D. Bogdanov A. M. Rodin S. I. Sidorchuk



Sintesis y caracterizacion de portadores magneticos coloidales. Aplicaciones al diseno de sistemas de liberacion de farmacos  

NASA Astrophysics Data System (ADS)

The present work is mainly dedicated to the synthesis and characterization of composite colloidal particles with a magnetic core (magnetite) and a polymeric biodegradable material shell (poly(DL-lactide), PLA). The aim is to use them as drug carrier systems in the field of controlled (or modified) release. The appropriate synthesis conditions are analyzed for such purpose, starting with the synthesis of the magnetic nuclei, and continuing with that of microspheres of the polymer used later as shell material. The final step is the manufacture of the composite colloids. In order to have a good comparison, all the experiments of the work have been run in triplicate, that is, for the three individual materials (magnetic nuclei, PLA and composite particles magnetite/PLA) and all the discussions are presented by way of parallel study of the three colloidal systems. The following surface and bulk properties have been studied: shape and size of the particles, specific surface area, chemical composition. The magnetic behavior of the nuclei is characterized, as well as that of the composite particles, through measurement of the magnetic susceptibility and the hysteresis cycles. In addition, a study of the electrokinetic behavior of the systems as a function of pH---at constant ionic strength---has been complemented by an investigation of their surface thermodynamics to check the extent of coverage achieved. Very significant results were also obtained in the analysis of the stability of the suspensions. Since our final aim was the design of a drug carrier and controlled release system, we also present a series of preliminary results concerning the effect of the glucocorticoid betamethasone 21-phosphate sodium salt on the surface electrical properties of the three kinds of particles, observing clear differences between the behavior of magnetite particles and of composite or pure polymeric colloids. It is demonstrated that the polymer layer affects considerably the capacity of the colloid for adsorbing this drug and, probably, other drugs of interest in the treatment of those pathologies in which one needs an elevated local concentration of any therapeutic product but without adverse side effects, like those used in the chemotherapy of the solid tumors.

Gomez Lopera, Salvador Angel



Sobre a quantizacao de um sistema classicamente caotico. (Quantization of classically chaotic system).  

National Technical Information Service (NTIS)

Some propeties of a quantization in terms of observables of a classically chaotic system, which exhibits a strange are studied. It is shown in particular that convenient expected values of some observables have the correct classical limit and that in thes...

N. F. Godoy



Sistema de Recomendações em Discussões Eletrônicas - Apoio à Construção do Conhecimento em Comunidades Virtuais de Aprendizagem  

Microsoft Academic Search

Internet enables the construction and sharing of knowledge without physical frontiers. Despite all the technologies available for online discussions, the knowledge shared through electronic media could be better utilized. Following the socio-interactionist theory of Vygotsky (1984), this paper presents the SisRecCol system, that analyzes the themes discussed in a chat room and then recommends information sources in a personalized way,

Adriana Justin; Cerveira Kampff; Stanley Loh; Daniel Lichtnow; José Palazzo; Moreira de Oliveira


Los contaminantes ambientales bifenilos policlorinados (PCB) y sus efectos sobre el Sistema Nervioso y la salud  

Microsoft Academic Search

SUMMARY Environmental pollution is a world-wide issue which is a matter for concern among the international community. Great industrialized cities are the most polluted and Mexico City is among them. However, pollution affects places which are far away from contaminated urban areas, thus damaging eco-systems. Environmental pollution is responsible for an alarming and increasing list of illnesses in humans, animals

Carolina Miller-Pérez; Eduardo Sánchez-Islas; Samuel Mucio-Ramírez; José Mendoza-Sotelo; Martha León-Olea



Filmes supercondutores do sistema YBaCuO. (Superconducting films of YBaCuO).  

National Technical Information Service (NTIS)

Thick films of YBa(sub 2) Cu(sub 3) O(sub 7) (sub -) (sub x) have been prepared on alumina and YSZ (Yttria-stabilized zirconia) substrates by the screen printing technique. Several experimental conditions have been studied, for instance: sintering time, t...

A. L. Coelho



Los sistemas de cúmulos globulares de NGC 3258 y NGC 3268 en el cúmulo de Antlia  

NASA Astrophysics Data System (ADS)

The Antlia Cluster is the third nearest galaxy cluster after Virgo and Fornax. We used images obtained with the MOSAIC camera (36'x 36') at the 4-m CTIO telescope in the bands Kron-Cousins R and Washington C to study the globular cluster systems of the two brightest galaxies. The elliptical galaxies NGC 3258 and NGC 3268 both contain several thousand clusters (Dirsch et al. 2003). The color distributions of both systems are clearly bimodal. Their number density profiles are similar, which also applies for the red and blue cluster subpopulations. The light profile of NGC 3268 resembles that of NGC 1399, the central galaxy of the Fornax cluster. NGC 3258 has a steeper light profile at large radii. Both galaxies show color gradients, becoming bluer outwards. The globular cluster systems closely trace light profiles of their respective host galaxies in the studied radial regime. The elongation of the cluster systems is approximately aligned with an axis that connects the two galaxies. We obtain specific frequencies, within a radial range of 4', of {S}N=3.0 ±2.0 for NGC 3268 and {S}N=6.0±2.5 for NGC 3258.

Bassino, L. P.; Dirsch, B.; Richtler, T.


El programa de Educación Maternal en el Sistema Público de Salud en Galicia  

Microsoft Academic Search

Aims of the studyThe goals of this study have been to know the number of patients who participate in the Maternal Education Program in the Health Centers in Galicia. Timetable, theoretical and practical activities of the program have been analised.

A. Martínez Rodríguez; S. Martínez Bustelo; S. Pita Fernández; A. Ferri Morales



[Distribution and taxonomy of Pyrgophorus platyrachis (Caenogastropoda: Hydrobiidae) in the Sistema de Maracaibo, Venezuela].  


The presence of a microgastropod identified as Potamopyrgus sp. was detected previously in the Maracaibo System; nevertheless, a detailed morphological analysis identified this snail in other genera. The objective of this work is to update the distribution and taxonomy of Pyrgophorus platyrachis in the Maracaibo System, Venezuela in samples obtained between 2001 and 2009. The presence of hundreds of individuals of P. platyrachis were observed in the estuary, indeed in the localities of the Gran Eneal lagoon (4 111 snails), Peonías lagoon (229 snails), Punta Capitán Chico (758 snails), San Francisco (2 517 snails), Curarire (240 snails), Apon River mouth (173 snails), Ojeda City (240 snails), Bachaquero (128 snails) and Tomoporo de Agua (385 snails). We performed a taxonomical analysis, and emphasized in ecological aspects, such as the distribution of the species and habitat features, as near vegetation and type of associated sediment. We found three morphotypes of the species, one smooth, another with spiral striations and the other with spines. Smooth morphotype was exclusive of the Gran Eneal lagoon, Peonías lagoon, Punta Capitan Chico and Apon River mouth localities, whereas the other two morphotypes were found together in the remaining localities. According to our detailed anatomical and taxonomical analysis we propose a synonymy between P. platyrachis and the other species described like Pyrgophorus parvulus and Pyrgophorus spinosus. PMID:22017122

Nava, Mario; Severeyn, Héctor; Machado, Nakary



Contenidos para un Intranet Basada en un Sistema de bases de datos Distribuidas Inteligentes  

Microsoft Academic Search

In the region of Extremadura the installation of an Intranet has been completed IP like support for its technological development. The problem now is to determine the contents in function of its use. We propose a system for the administration of contents in the Primary teaching. As users, the students and professors, the only thing that they expect from the

Juan Arias Masa; Ricardo Luengo González; Miguel Ángel Martín Tardío


Lesões no Sistema Músculo-Esquelético em Bailarinos Profissionais, em Portugal, na Temporada 2004\\/2005  

Microsoft Academic Search

Introduction: Dance is a predisposing activity to the occurrence of injury, being physically and psychologically demanding, with various injuries' risks. General purpose: To determine the annual injuries prevalence in professional dancers (in Portugal) and to characterize the occurrence pattern and severity and risk factors (2004\\/2005 season). Relevance: To analyse injuries and respective risk factors, in order to bet itself in

Ana Paula Azevedo; Raúl Oliveira; João Pedro Fonseca


Desarrollo de un sistema sensor para la cuantificación de glucosa en jugos de frutas  

Microsoft Academic Search

A sensor system for the determination of glucose in fruit juices using an enzymatic reactor packed with the immobilized gluco- se oxidase enzyme is proposed. The determination is based in a series of reactions, which area carried out sequentially in different places of the manifold: 1) oxidation of the glucose, by means of immobilized glucose oxidase, to form H2O2, 2)

Adriana Noemí; Ángeles Cañas




Microsoft Academic Search

In the current context of the Water Treatment Plant, and in view of the great development of the modular constructive systems, the importance of related studies about treatment prototypes that have possible to use these constructive system gains fundamental importance, to as if will get to manufacturing its construction, becoming the execution quickly and rational. Thus, in a regard of

Tarso Luís Cavazzana; Tsunao Matsumoto


Tumores experimentais do sistema nervoso central: padronização de modelo em roedores utilizando a linhagem 9L  

Microsoft Academic Search

RESUMO - Grande variedade de modelos experimentais foram estabelecidos em neuro-oncologia durante as últimas décadas, a fim de estudar a biologia tumoral e a eficiciência de novas drogas e novos tratamentos em gliomas malignos humanos. Embora estes modelos estejam bem caracterizados e sejam facilmente reproduzíveis e aplicáveis, há limitações quanto ao seu uso e à resposta obtida, principalmente quando utilizados

Custódio Michailowsky; Flavio Key Niura; Ângela C. do Valle; Shigueko Sonohara; Thales D'Alessandro Meneguin; Ana Maria C. Tsanaclis




Microsoft Academic Search

The paper places in perspective the mechanisms of production of the Brazilian visual arts and the political situation of repression lived in the country under dictatorship. The paper studies the relevance, forms of confrontation and production of a parcel of the Brazilian visual artists who had continued producing or had theirs actions influenced by national political situation of extreme repression

Felipe Scovino


Um modelo do sistema termorregulador do corpo humano: exposição a ambientes quentes  

Microsoft Academic Search

A transient mathematical model for the human heat transfer system has been developed. It is based on a single cylinder, representing the body, with four concentric annular layers: core, muscle, fat and skin. It includes metabolic heat generation, conduction of heat in tissue, convection of heat by flowing blood, heat transfer by radiation, convection and evaporation at the surface and

M. S. Ferreira; J. I. Yanagihara


Informática na Fisioterapia: Sistema Multimídia de Apoio ao Aprendizado dos Testes de Força Muscular  

Microsoft Academic Search

This work describes a tutorial system development for the support to muscular strength tests learning. These tests are essential for a physical therapy diagnosis. This subject is crucial for the physical therapist. Its importance and complexity motivated the development of TFM, a multimedia learning support system. It integrates hypertext, movies, animated pictures and sound as recommended by construtivism paradigm. We

Luciana V. Castilho; Heitor S. Lopes; Wagner R. Weinert


Sistemas de producción de Spondias purpurea (Anacardiaceae) en el centro-occidente de México  

Microsoft Academic Search

Production systems of Spondias purpurea (Anacardiaceae) in Central West México. Morphological, physical and chemical traits related with fruit quality characteristics of Spondias purpurea L. agroecosystems were studied in Central-West Mexico for wild and cultivated populations. Spondias purpurea regularly thrive in shallow, rocky infertile soils unsuitable for conventional crops. The weight, axial and radial length, pH, total soluble solids (SST), reducing

Blanca C. Ramírez Hernández; Pimienta Barrios Eulogio; Javier Z. Castellanos Ramos; Alejandro Muñoz Urias; Guadalupe Palomino Hasbach; Enrique Pimienta Barrios



Flutuação populacional e danos de Grapholita molesta (Lepidoptera: tortricidae) em dois sistemas de produção de pessegueiros  

Microsoft Academic Search

With the objective to know the population fluctuation of Grapholita molesta and to verify the phenological stage that the peach tree is more sensitive to the attack of the insect in two production systems, four peach orchards were selected, two under the conventional production system (CP) and two under the good agricultural practice system (GAP), in 2005\\/06 and 2006\\/07 growing

Alex Sandro Poltronieri; Lino Bittencourt Monteiro; Louise Larissa May-de-Mio



Malformación del sistema pancreático-biliar como causa de perforación espontánea de la vía biliar extrahepática  

Microsoft Academic Search

SUMMARY Biliary ascitis usually results from a spontaneous or traumatic perforation of the common bile duct, usually at the junction with the cystic duct. Distal duct obstruction, pancreatic fluid reflux up the common bile duct, congenital weakness or a localized mural malformation of the wall of the common duct have been proposed as possible causes. We present an 11-months-old infant

Carlos Baeza-Herrera; Ulises Darío Medellín-Sierra; Héctor Sanjuán-Fabián; Newton Jiménez-González; Luís Manuel; García-Cabello


Cuantificacion de la radiacion de la estructura en sistemas de caja cerrada  

NASA Astrophysics Data System (ADS)

In the present work a contribution to the study of the quantification of the radiation of the structure walls in systems of closed box has been made, establishing a relation of the vibroacustic response of this type of radiating systems with the characteristics of the material used, such as the Young modulus, the damping, or the density. From a general point of view, the object of the work fits within the problems of dynamic fluid-structure interaction, so the presented foundations of the procedures and models, are similar to the used in other dominions of application, like the construction, aeronautics, naval construction, Biology, etc. In order to approach the problem, a mecano-acoustic couple between the different elements from the radiating system is considered. Ideally, in the radiating systems composed of loudspeakers mounted on an acoustic enclosure or box, the walls of the box are considerated infinitely rigid with null movement. In the reality, the experience demonstrates that the walls behave like vibrant plates under the action of the inner pressures, and contribute to the final radiation of sound of the system, mainly in the low frequencies range. To obtain the proposed objective, first a series of experimental measures has been made on models of closed box with and without loudspeaker. In the experimental procedure the vibracional behavior of the walls of the structure has been studied by means of modal analysis and measures of vibration. The acoustic response of the systems is evaluated by means of measures of acoustic pressure and intensity. Next, numerical models of the loudspeaker, inner air and structure have been implemented. The implemented numerical models are mechanical-acoustic, the electrical part of the loudspeaker has been replaced by a harmonic excitation force. The first numerical model is three-dimensional, looking for obtaining a simulation of the simultaneous interaction of the three main elements of the system: the inner air of the box, the diaphragm of the loudspeaker, and the walls of the box. Moreover another numerical model in two dimensions has been implemented, adding the air outside of the box, and obtaining a fluid-structure-fluid couple. With both models a parametric study been made. In sumary the structure colors the sonorous response of the system in all the studied frequency range, due to resonances or forced vibrations of the walls. On the other hand the proposed numerical model supposes an advance with respect to the presented ones until the moment. The model constitutes a design tool that allows to study in an economic form, the importance of the structure in the sonorous response of the system.

Segura Alcaraz, Jorge G.


Dyes and biomimetic systems: detergency and food industry Colorantes y sistemas biomiméticos: detergencia e industria alimentaria  

Microsoft Academic Search

Dyes are widely used as additives in the food industry. As some dyes may pose health risks when being in contact with food, their removal in industrial processes is an important issue. Since the surfactant sodium dodecyl sulphate (SDS) covers a wide range of variety of task to remove oily materials, and it is often used in detergency processes, the

G. Astray; A. Cid; J. A. Manso; O. Moldes; J. Morales; J. Quintás



Sistema avtomaticheskogo radiometricheskogo kontrolya tekhnologicheskogo protsessa. (Automatic radiometric control system of technological process).  

National Technical Information Service (NTIS)

A system of remote automatic control for radiochemical and technological processes connected with radioactive substances is described. The control system is created on the MERA-60 computer basis and block complex in the CAMAC format. The computer outer de...

N. I. Kroshkin V. I. Nazarenko V. A. Safonov V. A. Krivosheev V. D. Loginov



Valutazione delle preferenze di consumatori campani per un sistema di etichettatura generico sulle \\  

Microsoft Academic Search

Our study is aimed at evaluating whether or not different food miles information displayed on labels such as information on the distance and time that the food traveled (nKm) and information on CO2 emission (CO2) during food transportation can affect consumer choice in the case of fresh tomato product. We also examined: (i) the level of sensitivity and knowledge of

Vincenzina Caputo; Maurizio Canavari; Jr. Rodolfo M. Nayga



Exploración con GEMINI-GMOS del sistema de cúmulos globulares de NGC 5044  

NASA Astrophysics Data System (ADS)

We present preliminary results of the first photometric study of the globular cluster system associated to the elliptical galaxy NGC 5044, the dominant object in the homonymous group. These results are based on data recently (semester 2009A) obtained with the Multi Object Spectrograph GMOS at the Gemini South telescope. FULL TEXT IN SPANISH

Faifer, F. R.; Cellone, S. A.; Smith Castelli, A. V.; Bassino, L. P.; Forte, J. C.


El consumo de los hogares colombianos, 2006-2007: Estimación de sistemas de demanda  

Microsoft Academic Search

Using household data from the 2006 Income and Expenditure survey, we provide a new estimation of demand systems for Colombia. We estimate three different specifications of demand systems, namely, the Linear Expenditure System (LES), the Extended Linear Expenditure System (ELES) and the Almost Ideal Demand System (AIDS). We also calculate expenditure, income and price elasticities for different groups of goods.

Darwin Cortés; Jorge Eduardo Pérez




Microsoft Academic Search

The proposed project intends to utilize different hydroponics systems whits Aeroponics that allow to create a cooling zone covering the entire plant (aerial and root parts). However, there is the necessity to adapt the Aeroponics system in order to cool the plant environment (nutritive solution and the air). It will be utilized three types of systems to cultivate the hybrid



Il sistema della sicurezza alimentare attraverso le definizioni del regolamento 178\\/2002  

Microsoft Academic Search

The Food Safety System Through the Definitions of Reg. 178\\/2002 (by Eva Rook Basile) - This paper aims to present the food safety system, introduced with Reg. 178\\/2002 of 28 January 2002, as the final stage of a long series of EU interventions to regulate health and competition within the food industry. The problem the EU had to tackle was

Eva Rook Basile




Microsoft Academic Search

Conservation tillage may affect soil phosphorus (P) fractions through the application of P fertilizer and the deposition of residue on the soil surface. The objectives were to 1) evaluate the effect of tillage systems on soil P fractions, as well as the interaction with P fertilization, and 2) relate changes in P fractions with P balance. No tillage and conventional




Microsoft Academic Search

For sustainable banana production, the EARTH University's Agro-commercial Enterprise has investigated management alternatives for the biodegradable banana residues from harvest and packing processes. Several investigations have been carried out in the area of organic fertilizer production as a way of optimizing resources and EM-compost with forced aeration was found to be a viable alternative. Using the results of these experiments,

K. Reátegui; H. Zenteno; C. Hernández; L. Quirós


Anomalias de la gravedad basadas en el sistema geodésico dereferencia 1980.  

NASA Astrophysics Data System (ADS)

The computing formulae for the determination of gravity anomalies in the 1980 Geodetic Reference System are presented, as well as the transformation formulae from the 1967 G.R.S. to the 1980 one. An application is made.

Sevilla, M. J.



Microsoft Academic Search

Water use efficiency (WUE) permits to evaluate the effect of water, soil and plant management on water consumption and yield of crop. The aim of this research was to determine the influence of soil tillage on WUE for irrigated beans. The experiment was realized in plots located at Faculdade de Engenharia Agrícola of UNICAMP, in September to December period of

Gerson Araujo de Medeiros; Luiz Antonio Daniel; José Ricardo Freitas Lucarelli


Resonancias en la región trans-neptuniana  

NASA Astrophysics Data System (ADS)

La expansión de la órbita del planeta Neptuno en la etapa de acreción del Sistema Solar exterior (Fernández e Ip 1984, 1996) parece ser un mecanismo eficiente para la captura de planetesimales en las resonancias exteriores con Neptuno (Malhotra 1995). Por otro lado, los estudios dinámicos realizados por varios autores indican que las resonancias son regiones de evolución estable, en contraste con el comportamiento caótico del resto de la región trans-neptuniana. Por estas razones, y si bien los datos observacionales son todavía muy limitados, se supone que los objetos descubiertos se encuentran en alguna de esas resonancias. En esta comunicación presentamos un estudio analítico y numérico de las principales resonancias exteriores con Neptuno.

Gallardo, T.; Ferraz-Mello, S.


Evolución de planetas gigantes y posibilidades de su detección directa  

NASA Astrophysics Data System (ADS)

Desde la reciente detección de planetas gigantes orbitando estrellas cercanas de tipo solar por medio de efecto Doppler, uno de los principales problemas, en cuanto al estudio de los sistemas planetarios extrasolares, se refiere a la posibilidad de obtener evidencia directa de su existencia. Esto parece ser factible gracias a que en un futuro cercano entrarán en operación algunos telescopios especialmente adecuados a estos propósitos. Por tal motivo, hemos comenzado desde hace un tiempo un esfuerzo en cuanto al estudio de la evolución planetaria. A tales efectos hemos adaptado el código de evolución estelar de nuestro Observatorio al caso planetario. Las principales diferencias entre el caso estelar y el planetario se encuentran en la ecuación de estado. A tales fines hemos incluído la reciente ecuación de estado de Saumon, Chabrier y Van Horn, las opacidades radiativas de Guillot et al., procesos de quema de Deuterio, etc. También se ha considerado la posible existencia de fases de hielo y roca en el interior planetario. Por el momento hemos despreciado los efectos de la rotación planetaria. Con este código hemos computado la evolución de planetas con masas desde 10 hasta 0.3 masas de Júpiter. Utilizando nuestros resultados numéricos discutimos la detectabilidad de estos objetos en condiciones realistas.

Brunini, A.; Benvenuto, O. G.


Can DNS-Based Blacklists Keep Up with Bots?  

Microsoft Academic Search

Many Internet Service Providers (ISPs), anti-virus com- panies, and enterprise email vendors use Domain Name System-based Blackhole Lists (DNSBLs) to keep track of IP addresses that originate spam, so that future emails sent from these IP addresses can be rejected out-of-hand. DNSBL operators populate blocking lists based on complaints from recipients of spam, who report the IP address of the

Anirudh Ramachandran; David Dagon; Nick Feamster



Variations in the large surface protein gene of hepatitis B virus in vivo: a longitudinal study and application  

Microsoft Academic Search

AIM: To develop a method for longitudinal study of variations in the large surface protein gene of hepatitis B virus (HBV) in vivo and apply it to the investigation of the dynamics of HBV quasispecies. METHODS: Two HBV carriers were included in the study. Patient 1 was a 38-year-old male who received no anti-virus therapy before and dur- ing the

Nan Yu; Jin Cui; Guo-Bao Zhou; Yun-Jiao Zhang; Jing-Li Chen


ZDVUE: prioritization of javascript attacks to discover new vulnerabilities  

Microsoft Academic Search

Malware writers are constantly looking for new vulnerabilities to exploit in popular software applications. A successful exploit of a previously unknown vulnerability, that evades state-of-the art anti-virus and intrusion-detection systems is called a zero-day vulnerability. JavaScript is a popular vehicle for testing and delivering attacks through drive-by downloads on web clients. Failed attack attempts leave traces of suspicious activity on

Sandeep Karanth; Srivatsan Laxman; Prasad Naldurg; Ramarathnam Venkatesan; J. Lambert; Jinwook Shin



Design and Implementation of a Secure Modbus Protocol  

Microsoft Academic Search

The interconnectivity of modern and legacy supervisory control and data acquisition (SCADA) systems with corporate networks\\u000a and the Internet has significantly increased the threats to critical infrastructure assets. Meanwhile, traditional IT security\\u000a solutions such as firewalls, intrusion detection systems and antivirus software are relatively ineffective against attacks\\u000a that specifically target vulnerabilities in SCADA protocols. This paper describes a secure version

Igor Nai Fovino; Andrea Carcano; Marcelo Masera; Alberto Trombetta



Effects of zhaoyangwan on chronic hepatitis B and posthepatic cirrhosis  

Microsoft Academic Search

AIM: To study the therapeutic effects of zhaoyangwan (ZYW) on chronic hepatitis B and hepatic cirrhosis and the anti-virus, anti-fibrosis and immunoregulatory mechanisms of ZYW. METHODS: Fifty cases of chronic hepatitis B and posthepatic cirrhosis with positive serum HBsAg, HBeAg, anti-Hbc and HBV-DNA were divided randomly and single-blindly into the treatment group (treated with ZYW) and the control group (treated

Cui-Ping Zhang; Zi-Bin Tian; Xi-Shuang Liu; Qing-Xi Zhao; Jun Wu; Yong-Xin Liang


A Robust Technique of Anti Key-Logging using Key-Logging Mechanism  

Microsoft Academic Search

System security and privacy always have to face new confronts. Continuous updates in the operating systems and anti-virus applications strive to amplify the system security level. In recent years 'key-loggers' have proved to be one of the prevalent intimidations to security and privacy. Key-logger is a surreptitious surveillance application, which is used to keep record of user's activities on the

Muzammil M. Baig; W. Mahmood



WORM vs. WORM: Preliminary Study of an Active Counter›Attack Mechanism  

Microsoft Academic Search

Self-propagating computer worms have been terrorizing the Internet for the last several years. With the increasing den- sity, inter-connectivity and bandwidth of the Internet com- bined with security measures that inadequately scale, worms will continue to plague the Internet community. Existing anti-virus and intrusion detection systems are clearly inade- quate to defend against many recent fast-spreading worms. In this paper

Frank Cast; Emre Can Sezer; Jun Xu


WORM vs. WORM: preliminary study of an active counter-attack mechanism  

Microsoft Academic Search

Self-propagating computer worms have been terrorizing the Internet for the last several years. With the increasing density, inter-connectivity and bandwidth of the Internet combined with security measures that inadequately scale, worms will continue to plague the Internet community. Existing anti-virus and intrusion detection systems are clearly inadequate to defend against many recent fast-spreading worms. In this paper we explore an

Frank Castaneda; Emre Can Sezer; Jun Xu



Information Technology Services Newsletter: Spring 2005  

Microsoft Academic Search

C O N T E N T S New Lab PCs, Campus Computing in Top Ten 1 Managing E-mail Quotas 2 Identity Management System Enabled, Faculty Access To COCIDs 3 Computer Training Workshops 4 ANGEL 6.2, Camtasia, Resnet 5 AntiVirus 6 Users In The News 7 Technology Survey 8 PCount Pilot, Sympodium Interactive Pen Display 8 Wireless Update 8 New

Mary Jo Orzech



Information Technology Services Newsletter: Spring 2004  

Microsoft Academic Search

C O N T E N T S ANGEL 6.0, Smart Classroom, NetOP 1 Anti-Virus FAQ, Websites, Faculty\\/Staff Technology Support Initiative, MINITAB 2 CTC Survey, Printing 3 Web Building, Assistive Technology, IT Spotlight 4 Web Accessibility, SUNY Learning Network 5 SUNY Training Center, EASI Training 6 Library Database Training,ITSS Software Training 7-8 FAQ’s - Firewalls, Spyware, SPAM, E-mail Filters 9

Mary Jo Orzech



Immune responses and protection induced by mucosal and systemic immunisation with recombinant measles nucleoprotein in a mouse model of measles virus-induced encephalitis  

Microsoft Academic Search

Summary.  ?In this study the immunogenicity of recombinant nucleoprotein (Np) administered intranasally or intraperitoneally, and its\\u000a ability to support a systemic protective anti-virus antibody response was examined, in a mouse model of measles virus (MV)-induced\\u000a encephalitis. Although both intranasal and intraperitoneal routes of immunisation resulted in priming Np-and MV-specific T-cell\\u000a responses, the intraperitoneal route was shown to prime for a predominantly

W. Olszewska; J. Erume; J. Ripley; M. W. Steward; C. D. Partidos



Influence of arachidonic acid and phytoviruses on the hormonal system of potato plants grown in vitro  

Microsoft Academic Search

Changes in the phytohormonal system during the development of antivirus resistance was investigated. This resistance was induced\\u000a by arachidonic acid (AA) in potato plants (Solanum tuberosum L.) grown in vitro. The plants in tubes were treated with AA 7 days before infection with tobacco mosaic virus or potato X virus. These plants\\u000a were used for ABA, IAA, and cytokinin quantification.

N. A. Rozhnova; G. A. Gerashchenkov



Aktivitas imunostimulan susu kedelai terhadap imunoglobulin (IgG, IgA) dan proliferasi sel limfosit pada mencit Balb\\/c yang diinduksi hepatitis A Immunostimulant activity of soybean milk against immunoglobulin (IgG, IgA) and lymphocyte cells proliferation of Balb\\/c mice induced hepatitis A  

Microsoft Academic Search

Soybean milk contains of isoflavon aglycon as genestein and rich of proteins. The genestein of soybean milk potentially has antitumor\\/anticancer, antivirus, antiallergic activities and immunity responses. The aim of this research was to evaluate the immunostimulant activity of soybean milk against immunoglobulin (IgG and IgA) and lymphocyte cells proliferation in Balb\\/c mice induced by hepatitis A. The test was done

Ediati Sasmito



[The flu syndrome: update and therapeutic and prophylactic approach].  


Authors in the present work analyse the history of the flu from V century A.C. until our days. We can know the different flu epidemic the structure of the virus and to take note of the different preventing device; of these the core is the vaccine. Thanks the vaccine is possible to weaken the big epidemics. Authors attract the importance on the mass vaccine and conclude to mention the new antivirus drugs per os. PMID:11865535

Abetti, P; Bossi, A; Monaco, E; Melino, C; Messineo, A



Microsoft Academic Search

This reflective paper examines relationships between the Government policy-makers in health; health care providers in general; and the adoption of health care information, knowledge, and communication technologies. These technologies include the adoption of a national health language and computer science standards in health. These reflections are based on the author's observations and international involvement in the development of standards and

Evelyn Johanna; Sophia Hovenga; Hovenga EJS



Esteróides anabolizantes: mecanismos de ação e efeitos sobre o sistema cardiovascular Anabolic steroids: action mechanisms and effects on the cardiovascular system Esteroides anabólicos: mecanismos de acción y efecto sobre el sistema cardiovascular  

Microsoft Academic Search

Anabolic androgenic steroids are ergogenic aids commonly used by athletes in search of better performances. However, the use of these substances by individuals who are not athletes with aesthetic aims is becoming an increasing problem in fitness and sport centers. This behavior has favored the indiscriminate and abusive use of these steroids, exposing their users to health risks. Anabolic steroids

Fernando Lima Rocha; Fernanda Roberta Roque; Edilamar Menezes de Oliveira



Microsoft Academic Search

SUMMARY EVALUATION OF THE ANTIOxIDANT ACTIVITy USING THE B-CAROTENE\\/LINOLEIC ACID SySTEM AND THE DPPH SCAVENGING METHOD. The antioxidant activity of fruit extracts (acerola, açaí, black-berry and strawberry) and pure compounds has been analysed by two methods: ?-carotene\\/linoleic acid and DPPH•(2,2-diphenyl-1-picrylhydrazyl) radical scavenging assay. First, those methodologies were adapted to be performed in microplates, in order to reduce the sample and

Joaquim Maurício DUARTE-ALMEIDA; Ricardo José dos SANTOS; Maria Inês GENOVESE; Franco Maria LAJOLO



Microsoft Academic Search

The hydrological model SHALL3 was conceived with physically-based parameters, nevertheless, those that presented uncertainties or heterogeneities were fitted. The model was applied in the Ludueña's basin (Santa Fe, Argentina). Data of precipitation, evaporation, flows, limnigraphs and water-table are available. As calibration parameters was taken (a) two coefficients for the vertical hydraulic conductivity adjustments, (b) the critical suction and the pores

Erik Daniel Zimmermann



Microsoft Academic Search

Los laboratorios de análisis clínicos constituyen un área en la cual coinciden muchos agentes potencialmente agresivos, tanto para la salud del personal y de las personas que acuden a recibir los servicios que se prestan, así como para las propias instalaciones. Debido a ello, todos los procedimientos analíticos conllevan a un riesgo, que aumenta con la introducción de nuevas tecnologías,

José Sánchez Díaz; Caridad Milanés Reyes; Osvel García Riverón



O carater de Chern-Connes para C^*-sistemas dinamicos calculado em algumas algebras de operadores pseudodiferenciais  

NASA Astrophysics Data System (ADS)

Given a C^*-dynamical system (A, G, ?) one defines a homomorphism, called the Chern-Connes character, that take an element in K_0(A) oplus K_1(A), the K-theory groups of the C^*-algebra A, and maps it into H_{{R}}^*(G), the real deRham cohomology ring of G. We explictly compute this homomorphism for the examples (overline{Psi_{cl}^0(S^1)}, S^1, ?) and (overline{Psi_{cl}^0(S^2)}, SO(3), ?), where overline{Psi_{cl}^0(M)} denotes the C^*-algebra generated by the classical pseudodifferential operators of zero order in the manifold M and ? the action of conjugation by the regular representation (translations).

Dias, David P.



Data Acquisition System Based on the RCA 1802 Microcomputer Sistema di Acquisizione Dati Basato Sul Microcalcolatore RCA 1802.  

National Technical Information Service (NTIS)

A data acquisition system is described. The system was implemented by adding to the RCA cosmac evaluation kit CDP 185020 an EPROM 2716 containing the BASIC interpreter, an EPROM 2716 with software for input-output management, an output gate of 8 bits in p...

P. Cerulli-irelli



Contribuicao de Dados de Satelite No Sistema de Previsao de Safras (Contribution of Satellite Data in the Crop Forecasting System).  

National Technical Information Service (NTIS)

Various studies demonstrated that data obtained from natural resources satellites can be used to improve the quality of agriculture statistics through the regression estimator. Experience acquired from a cooperation project INPE-IBGE, using LANDSAT-TM dat...

S. Chouchen




Microsoft Academic Search

Remote Sensing data and Geographic Information Systems (GIS) technologies have been used for land resource studies and land use\\/land cover mapping and monitoring in the Southeastern of Brazil. In this study those technologies were applied for land use change and soil erosion potential analysis. The study area selected is the Ribeirao Claro Valley, a small - watershed in central São

Sergio dos Anjos; Ferreira Pinto; Magda A Lombardo


Fabrication of Miniature Fluidic Components for an Integration System . Fabricacion de Componentes Fluidicos Miniatura. Integracion de Sistemas.  

National Technical Information Service (NTIS)

A method is presented for fabricating miniature fluidic elements using photochemical engraving. The experimental procedures, equipment, and results obtained with copper, bronze, and stainless steel are described. The assembly is described of the silhouett...

O. A. Szakalicki



Efectos difusivos en la formación de enanas blancas de Helio de baja masa en sistemas binarios cerrados  

Microsoft Academic Search

In the last years, and thanks to advances in observational techniques, many astronomers have discovered in a great number of binary radio-pulsars the presence of a helium white dwarf resulting from a previous evolutionary state in which the progenitor of this star experienced one or more episodes of mass transfer to the compact component in the pair. That is the

M. A. De Vito; O. G. Benvenuto



Comparación de dos sistemas de medida de las concentraciones de glucosa en líquido cefalorraquídeo en la anestesia intradural hiperbara  

Microsoft Academic Search

® (Beckman Coulter) con las reali- zadas con un glucómetro Ascensia EliteXL&Elite ® durante la anestesia espinal, después de administrar 10 mg de bupivacaína hiperbara para así disponer de un método rápido y fiable al medir las cifras de glucorra- quia durante una anestesia espinal continua y seguir su evolución. PACIENTES Y MÉTODOS: Estudio prospectivo de 34 pacientes bajo anestesia

J. Sánchez Morillo; J. Soliveres Ripoll; N. Estañ Capell; C. Solaz Roldán; P. Viñals Bellido; C. Quiñones Torrelo



Comparação entre o sistema Petrifilm RSA® e a metodologia convencional para a enumeração de estafilococos coagulase positiva em alimentos  

Microsoft Academic Search

SUMMARY COMPARISON OF PETRIFILM RSA SYSTEM WITH THE TRADITIONAL METHODOLOGY FOR THE ENUMERATION OF COAGULASE-POSITIVE IN FOODS. Foods are examined for the presence of coagulase-positive staphylococci using selective and differential media followed by characterization for coagulase, thermoestable nuclease, Gram and catalase tests. These tests may require up to four days to obtain the results, besides time and material used. The

Anderson de Souza Sant'ana; Denise R. Perdomo Azeredo



Sistema de injeção em fluxo espectrofotométrico para monitorar peróxido de hidrogênio em processo de fotodegradação por reação foto-Fenton  

Microsoft Academic Search

Fenton processes (Fe2+\\/H2O2\\/UV). Sample is injected manually in a carrier stream and then receives by confluence a 0.1 mol L-1 NH4VO3 solution in 0.5 mol L -1 H 2SO4 medium. The product formed shows absorption at 446 nm which is recorded as a peak with height proportional to H 2O2 concentration. The performance of the proposed system was evaluated by

Mirela C. Oliveira; Raquel F. Pupo Nogueira; José A. Gomes Neto; Wilson F. Jardim; Jarbas J. R. Rohwedder



Acuabio 1 estimula el metabolismo anaerobio y el sistema inmune innato de las larvas de goldfish y tilapia  

Microsoft Academic Search

Acuabio 1 is able to stimulate the anaerobic metabolism and immune system in goldfish and tilapia larvae. Acuabio 1 is an mixture of essential protein and amino acids able to generate an important effect at preliminary developmental states of aquatic organisms. When Acuabio 1 is used, it is able to synchronize and stimulate the offspring growth since early states speeding

Rebeca Martínez; Yamila Carpio; Yoelys Gómez; Manuel Raíces; Antonio Morales; Fidel Herrera; Osmany González; Reynold Morales; Mario P Estrada


Organización del trabajo y diseño del sistema de pago para la actividad de preparacion de materia prima  

Microsoft Academic Search

El presente trabajo fue realizado con el objetivo de resolver o disminuir el efecto negativo de dos problemas fundamentales que existían en la Fábrica de Tabacos Torcidos a mano para la Exportación Camajuaní, los cuales consistían en : 1ro La mala calidad de la materia prima y 2do El salario recibido por el grupo de trabajadores encargados de la preparación

Alexis Águila Espinosa; Silvia López Hernández



Air pollution and its impact on the cardiovascular system Poluição atmosférica e seu impacto no sistema cardiovascular  

Microsoft Academic Search

Despite the great medical advances, cardiovascular disease remains one of the major causes of mortality worldwide, especially in industrialized countries. It develops as a result of countless complex interactions between genetic factors such as those related to age, sex, family history, weight, and post-menopausal status in women; and to environment-related factors such as cigarette smoking, alcohol use, eating habits, physical

Marjorie Paris Colombini


Life Support Systems. Environment Booklet 1. Teacher's Edition=Sistemas vitales. Libro del medio ambiente 1. Manual para El Maestro.  

ERIC Educational Resources Information Center

|The booklet is part of a grade 10-12 social studies series produced for bilingual education. The series consists of six major thematic modules, with four to five booklets in each. The interdisciplinary modules are based on major ideas and designed to help students understand some major human problems and make sound, responsive decisions to…

California State Univ., Los Angeles. National Dissemination and Assessment Center.


Sistema podderzhki operatora petlevoj ustanovki. Analiz tekhnologicheskogo protsessa. (Support system for loop device operator. Analysis of technological processes).  

National Technical Information Service (NTIS)

The paper presents the results obtained from the analysis of controlling the loops of a research reactor. A method of optimized interaction of the operator and hardware of the control system by computeraided identification of the cause of regime violation...

V. V. Yakovlev A. A. Mozhaev A. V. Lyadin



Utilizacao de compensacao serie em sistema de subtransmissao e distribuicao. (Utilization of series compensation in subtransmission and distribution system).  

National Technical Information Service (NTIS)

The technique of series compensation in subtransmission and distribution systems as an alternative of voltage regulation is decribed, including its advantages in relation to the conventional methods of voltage regulations: the situations where the the ser...

M. S. Fontana



Tratamento de águas residuárias com alta concentração de lipídios em sistema de reatores combinados enzimático\\/biológico  

Microsoft Academic Search

This work presents the conception and discusses the results obtained from the operation of an integrated system composed of an expanded inverted bed enzymatic reactor and a horizontal- flow anaerobic immobilized (HAIB) biomass reactor for lipid-rich wastewater treatment, as well as compare this system with a control HAIB operating under the same conditions. This system was operated in a chamber

D. J. Silva; M. R. Modolo; M. B. Varesche; C. E. Blundi; M. Zaiat


Análisis comparativo de las herramientas de programación Web: PHP, ASP y JSP, bajo los sistemas operativos Linux y Windows  

Microsoft Academic Search

Web Programming has generated in consecuence the creation of several development tools, therefore is important to identificate which offer good performance and under Operative System. The Web programming tools analized were: PHP, ASP and JSP, using the Operative System Linux and Windows with a common criterias. It was a descriptive trial, developing a prototype for PHP, ASP and JSP, in

Daladier Jabba Molinares; Adalgisa Alcocer Olaciregui; Carmenza Rojas Morales


Aplicações de Microscopia Eletrônica de Varredura (MEV) e Sistema de Energia Dispersiva (EDS) no Estudo de Gemas: exemplos brasileiros  

Microsoft Academic Search

This paper presents results of SEM and EDS study in some Brazilian gemstones. Emerald from Campos Verdes (GO) contains several mineral inclusions as talc, dolomite, chromite, pyrite, magnetite, etc. Sylvite crystals was firstly identified by SEM\\/EDS. These salt inclusions suggest percolation of K-bearing fluids during emerald crystallization. Emerald from Campos Verdes present higher concentration of Cr +3 in the outer



Development of an Automatic System for Plotting Synoptic Charts Desenvolvimento Do Sistema de Automacao DA Plotagem de Cartas Sinoticas.  

National Technical Information Service (NTIS)

A computerized system for acquisition and presentation of weather data is discussed. Weather and navigation charts (sea and air) based on the resultant data are plotted with greater speed and accuracy.

M. F. P. Sepulveda J. A. G. Pereira



Sistema Grafico Para O Tracado de Cartas Sinoticas Por Computado (A Graphic System for Drawing Synoptic Maps by Computer).  

National Technical Information Service (NTIS)

A graphic computer system developed to draw synoptic charts and to store meteorological data in a data base at the Institute of Space Research is described. The system, SINOGRAFO, was used to trace the contour of South America and international boundaries...

S. R. M. Pellegrino J. A. G. Pereira



Sistema integral de gestión pública sobre la base de devengo. Experiencias en el ámbito de países de la OCDE  

Microsoft Academic Search

This paper analyses the way the budget works using the accrual system method as a basic hypothesis in conceptual coherence with the countable system, to configure a modern global system of public administration used to successfully tackle the goals that the public bodies have set. We analyse the experiences that are happening in different countries of the OECD sphere, as

José Ignacio Martínez Churiaque; Teodoro A. Caraballo Esteban; Gaizka Zubiaur Etcheverry



Ensino de Sistemas de Informac ¸ ˜ ao para Cursos de Graduac ¸ ˜ ao em Computac ¸ ˜ ao: Uma Experiencia Integrada e Inovadora  

Microsoft Academic Search

Teaching Information Systems in Computer graduation course s uses techniques already being applyed in market for some years, b ut when the aim is to integrate new technologies to systems practice at real or ganization environ- ments, new integrated and inovative approaches need to be us ed. This article presents a teaching proposal for Information Systems based on an inovative

Ghedini Ralha; Jorge Henrique Cabral Fernandes


Saenger: Un Sistema de Transporte Espacial Para El Siglo XXI (Saenger: A Space Transportation System for the 21ST Century).  

National Technical Information Service (NTIS)

A report on the German Saenger spaceplane system is presented. Saenger must be able to carry payloads into space at a lower cost than that offered by the Ariane 5/Hermes system, and must also be a basis for hypersonic passenger transportation. The first c...

J. A. Martinezcabeza



Efectos de las drogas dopaminérgicas sobre el sistema cardiovascular y liberación de insulina en sujetos sanos y diabeticos tipo 2  

Microsoft Academic Search

Diabetes mellitus is one of the most frequent diseases all over the world and is a public health problem due its acute and chronic complications. Actually, there are five different oral drugs regarding glycemia control in Type 2 Diabetes available in the United States, each one with a distinct mechanism of action. Dopamine, a neurotransmitter, precursor of noradrenaline, is responsible

F Contreras; M González; M Velasco



Microsoft Academic Search

SUMMARY Introduction and background Substance abuse in the world is reported higher among men than in women; nevertheless in different countries including Mexico, use has increased among women during recent years. The distribution among male and female population is different according to each substance. Prevalence among both populations shows a preference for illegal drugs: mariguana, cocaine, solvent-inhalants and in a

Arturo Ortiz; Alejandra Soriano; Denize Meza; Rosario Martínez; Jorge Galván



Implantação e funcionalidades de um sistema de informação geográfica mineral na Companhia Vale do Rio Doce - CVRD  

Microsoft Academic Search

This work develops a geoprocessing application model to the necessities of a mining company in technician works about geologic evaluation resources and mineral research, enclosing governmental factors. A model for the implantation of a System of Geographic Information is presented, with the use of geoprocessing techniques, the organization in a georreferenced data base is possible, centered and in the same

Patrícia Procópio Calazans


Sistema de adquisicion de datos para el espectrometro de resonancia paramagnetica electronica. (Data acquisition system for electronic paramagnetic resonance spectrophotometer).  

National Technical Information Service (NTIS)

In the Atomic and Molecular Physics Laboratory at the Physics Department of the Instituto Nacional de Investigaciones Nucleares (ININ), there is in operation an electronic paramagnetic resonance spectrometer (EPR). This equipment is utilized for determine...

R. Pena Eguiluz



Estudos do sistema de vacuo para um acelerador linear de eletrons. (Studies of vacuum systems for a linear electron acelerator).  

National Technical Information Service (NTIS)

In the study of vaccum parameter system in the structure of a linear electron accelerator feeded by radio-frequency, the periodical release of adsorbed gases should be considered. For high power machines a structure inside a vaccum shield are recommended....

O. L. Goncalez R. Silva



Sistema integrato per la progettazione delle condotte. (Gas pipeline design: Integrated system. Session 1, 4th ATIG symposium).  

National Technical Information Service (NTIS)

The computer-aided design system presented in this paper consists of an integrated package of computer codes which allow designers of gas pipelines to carry out all the various work phases leading towards a finished design. The key phases involve the prep...

S. Selandari S. Paolucci R. Fava E. Serafini




Microsoft Academic Search

The business, in the present world configuration, is characterized by globalization, production proc- esses' automation and fast technological evolution (including hardware, software and telecommunications). These changes lead to the valorization of human resources and information as strategic resources for the or- ganizations to promote competitive advantage and to guarantee their survival. In this context, organizations' needs for information exchange and

Fábio Câmara; Araújo de Carvalho; Ernesto Escosteguy Castro; M. Eng; Aline França de Abreu


Sistema baz dannykh fiziki chastits na ES EhVM. (Particle physics database system on ES computer).  

National Technical Information Service (NTIS)

Main features, data definition language, query and output facilities of the BDMS database management system are presented. Adaptation of the BDMS system and processors for the DOCUMENTS, EXPERIMENTS and REACTIONS databases makes the particle physics data ...

A. A. Lutskij Y. Stolyarskij



Efectos difusivos en la formación de enanas blancas de Helio de baja masa en sistemas binarios cerrados  

NASA Astrophysics Data System (ADS)

In the last years, and thanks to advances in observational techniques, many astronomers have discovered in a great number of binary radio-pulsars the presence of a helium white dwarf resulting from a previous evolutionary state in which the progenitor of this star experienced one or more episodes of mass transfer to the compact component in the pair. That is the case for PSR B1855+09 (van Kerkwijk, M. H., Bell, J. F, Kaspi, V. M., & Kulkarni, S. R. 2000, ApJ 530, L37), where the mass for the white dwarf is known accurately from measurements of the Shapiro delay of the pulsar signal, MWD = 0.258+0.028-0.016 M?; for PSR J02018 + 4232 (Bassa, C. G., van Kerkwijk, M. H., & Kulkarni, S. R. 2003, A&A, 403, 1067), the spectra confirm that the companion is a helium-core white dwarf of ? 0.2 M?. On the other hand, there are several authors (Ferraro, F., Possenti, A., Sabbi, E., & D'Amico, N. 2003, ApJ, 596, L211; Bassa et al. 2003) that have identified the optical binary companion to the BMSP PSR J1911 - 5958A, located in the halo of the Galactic globular cluster NGC 6752, like a blue star whose position in the color-magnitude diagram is consistent with the cooling sequence of a low-mass, ? 0.17 - 0.20 M?, low metallicity helium white dwarf at the cluster distance. Finally, the color and magnitude of the stellar companion for B 1620-26 indicate that is a white dwarf of 0.34 ± 0.04 M? (Sigurdson, S., Richer, H. B., Hansen, B. M., Stairs, I. H. & Thorset, S. E. 2003, Science, 301, 193S). This has motivated us to study the formation of low mass helium white dwarfs in the context of binary evolution. For that purpose, using the code of binary evolution, entirely developed in the Facultad de Ciencias Astronómicas y Geofísicas of the Universidad Nacional de La Plata, Argentina, we have investigated the effects of diffusive processes on the evolution of a star member of a close binary system. A similar study was performed for Althaus, L. G., Serenelli, A. M., & Benvenuto, O. G. (2001, MNRAS, 323, 471) but in that paper the mass transfer was mimicked by subtracting mass to a progenitor of 1 M? to obtain the mass for the desired object. Actually, our binary code has a full nuclear reactions network for hydrogen and helium burning that allowed us to follow the abundances of fifteen isotopes throughout the entire evolution of the star. We have also included a detailed equation of state. The mass loss treatment is non conservative. We have modified the conditions for the beginning and end of mass transfer episodes. In our previous version, we assumed it to occur when the stellar radius was greater or smaller, respectively, that the Roche Lobe radius for the star. This introduced numerical problems, especially at the end of mass transfer phases. We adopted H. Ritter (1988, A&A, 202, 93) formulation that considers a finite scale height in the stellar atmosphere. The numerical behaviour in much more satisfactory, besides that it constitutes a more appropriate description for the physical problem. We perform the calculations for the evolution of the primary star in a close binary system of initial mass 2 M?, initial period of 1 day, initial mass ratio of 1.4142 and solar metallicity. We have done the calculations in four cases: A) with diffusion and all Roche Lobe overflows, B) with diffusion and only the first Roche Lobe overflow, C) without diffusion and all Roche Lobe overflows, D) without diffusion and only the first Roche Lobe overflow. Cases B) and D) where performed to compare with results obtained for Althaus et al. (2001). The main conclusion of this work is that the age of these objects is mainly determined by diffusive effects, and the late stages of mass transfer, not considered in Althaus et al. (2001), constituted a minor effect on the scales of cooling times.

De Vito, M. A.; Benvenuto, O. G.


Comportamento dos sistemas de medicao em funcao da tarifa horosazonal - THS. (Measure systems behaviour based in season custom tariff).  

National Technical Information Service (NTIS)

The different measure systems are evaluated, based in the season custom tariff establishment, resulting in the load modulation and load reduction, during peak hour. Comparative analysis of the load curves are elaborated before and after the new tariff int...

S. Yshimaru A. A. Castro



Defense Islands in Bacterial and Archaeal Genomes and Prediction of Novel Defense Systems ?†‡  

PubMed Central

The arms race between cellular life forms and viruses is a major driving force of evolution. A substantial fraction of bacterial and archaeal genomes is dedicated to antivirus defense. We analyzed the distribution of defense genes and typical mobilome components (such as viral and transposon genes) in bacterial and archaeal genomes and demonstrated statistically significant clustering of antivirus defense systems and mobile genes and elements in genomic islands. The defense islands are enriched in putative operons and contain numerous overrepresented gene families. A detailed sequence analysis of the proteins encoded by genes in these families shows that many of them are diverged variants of known defense system components, whereas others show features, such as characteristic operonic organization, that are suggestive of novel defense systems. Thus, genomic islands provide abundant material for the experimental study of bacterial and archaeal antivirus defense. Except for the CRISPR-Cas systems, different classes of defense systems, in particular toxin-antitoxin and restriction-modification systems, show nonrandom clustering in defense islands. It remains unclear to what extent these associations reflect functional cooperation between different defense systems and to what extent the islands are genomic “sinks” that accumulate diverse nonessential genes, particularly those acquired via horizontal gene transfer. The characteristics of defense islands resemble those of mobilome islands. Defense and mobilome genes are nonrandomly associated in islands, suggesting nonadaptive evolution of the islands via a preferential attachment-like mechanism underpinned by the addictive properties of defense systems such as toxins-antitoxins and an important role of horizontal mobility in the evolution of these islands.

Makarova, Kira S.; Wolf, Yuri I.; Snir, Sagi; Koonin, Eugene V.



Design and Implementation of a Secure Modbus Protocol  

NASA Astrophysics Data System (ADS)

The interconnectivity of modern and legacy supervisory control and data acquisition (SCADA) systems with corporate networks and the Internet has significantly increased the threats to critical infrastructure assets. Meanwhile, traditional IT security solutions such as firewalls, intrusion detection systems and antivirus software are relatively ineffective against attacks that specifically target vulnerabilities in SCADA protocols. This paper describes a secure version of the Modbus SCADA protocol that incorporates integrity, authentication, non-repudiation and anti-replay mechanisms. Experimental results using a power plant testbed indicate that the augmented protocol provides good security functionality without significant overhead.

Fovino, Igor Nai; Carcano, Andrea; Masera, Marcelo; Trombetta, Alberto


Small-angle neutron scattering study of recombinant yeast-derived human hepatitis B virus surface antigen vaccine particle  

NASA Astrophysics Data System (ADS)

The overall and internal structure of recombinant yeast-derived human hepatitis B virus surface antigen vaccine particles was investigated by small-angle neutron scattering using the contrast variation method. The vaccine is a nearly spherical particle, and its contrast-matching point was determined to be at about 24% D2O content, indicating that a large part of the vaccine particle is occupied by lipids and carbohydrates from the yeast. The Stuhrmann plot suggests that the surface antigens exist predominantly in the peripheral region of the particle, which is favorable to the induction of anti-virus antibodies.

Sato, M.; Ito, Y.; Kameyama, K.; Imai, M.; Ishikawa, N.; Takagi, T.



Identification of Malicious Web Pages by Inductive Learning  

NASA Astrophysics Data System (ADS)

Malicious web pages are an increasing threat to current computer systems in recent years. Traditional anti-virus techniques focus typically on detection of the static signatures of Malware and are ineffective against these new threats because they cannot deal with zero-day attacks. In this paper, a novel classification method for detecting malicious web pages is presented. This method is generalization and specialization of attack pattern based on inductive learning, which can be used for updating and expanding knowledge database. The attack pattern is established from an example and generalized by inductive learning, which can be used to detect unknown attacks whose behavior is similar to the example.

Liu, Peishun; Wang, Xuefang


Malware distributed collection and pre-classification system using honeypot technology  

NASA Astrophysics Data System (ADS)

Malware has become a major threat in the last years due to the ease of spread through the Internet. Malware detection has become difficult with the use of compression, polymorphic methods and techniques to detect and disable security software. Those and other obfuscation techniques pose a problem for detection and classification schemes that analyze malware behavior. In this paper we propose a distributed architecture to improve malware collection using different honeypot technologies to increase the variety of malware collected. We also present a daemon tool developed to grab malware distributed through spam and a pre-classification technique that uses antivirus technology to separate malware in generic classes.

Grégio, André R. A.; Oliveira, Isabela L.; Santos, Rafael D. C.; Cansian, Adriano M.; de Geus, Paulo L.



System Toolbox  

NSDL National Science Digital Library

System Toolbox is designed for system administrators who deal with a variety of platforms. The site covers Windows NT, General Unix, Novell, Linux, Solaris, HP-UX, and the Mac OS. The "toolbox" for each platform offers annotated links to Tools (Disk Management, Anti-Virus, Security, etc.), Articles, and other useful Links. While the information here is hardly comprehensive, the site offers useful, if often basic, resources for administrators. System Toolbox's brand new History section looks promising, with two articles currently posted, "Von Braun's Slide Rule" and "The Godfather of Computing - Charles Babbage." The Comments section allows users to post questions or comments.




NSDL National Science Digital Library

Jumbo: the "official" shareware site of the Web. This searchable archive contains over 24,000 shareware and freeware programs. Categories include: business, home and personal, programming, utilities, and words and graphics. Within each category, programs are cataloged by operating system. The entire archive is a searchable by program category and operating system. There is a short annotation with the programs to help determine whether to download them or not. Size of program is given. A "starter kit" of a decompression and anti-virus program is also provided for each operating system. This is an excellent specialty site.



Defining the dynamics of groundwater in Serra da Estrela Mountain area, central Portugal: an isotopic and hydrogeochemical approach  

NASA Astrophysics Data System (ADS)

In a multidisciplinary approach, geological, geomorphologic, structural, hydrogeochemical and isotopic surveys were conducted on the Serra da Estrela groundwater system (central Portugal) in order to establish/develop a conceptual circulation model of the Caldas de Manteigas thermomineral system. A detailed study of the isotopic and geochemical composition of surface waters (e.g. Zêzere River), shallow groundwaters (cold dilute springs), and thermomineral waters was carried out to characterize the distribution of isotopes in waters of this mountainous region, and to determine the origin and possible recharge locations of the thermomineral system. Special attention was dedicated to isotopic tracers and their role in the definition of the thermomineral waters’ conceptual model, considering: (1) the ?18O fractionation gradient; (2) the mean isotopic composition of the thermomineral waters in the region; and (3) the estimation of snowmelt contribution as a source of groundwater recharge at Serra da Estrela. The recharge of the thermomineral aquifer takes place on the more permeable zones of the granitic massif, associated with the main tectonic structures, whereas the recharge of the shallow aquifers seems to take place mostly in the plateaus, although another part of the recharge may occur in the slopes of the Zêzere River valley. Une approche multidisciplinaire, géologique, géomorphologique, structurale, avec études hydrogéochimique et isotopique a été conduite sur le système aquifère souterrain de Serra da Estrela (Portugal central) afin de construire un modèle conceptuel de circulation du système thermo minéral de la Caldas de Manteigas. Une étude isotopique et géochimique détaillée de la compositition des eaux de surface (e.g. rivière Zêzere), des eaux superficielles (sources froides diluées), et des eaux thermo minérales, a été effectuée pour caractériser la distribution des isotopes dans les eaux de cette région montagneuse et pour déterminer l’origine et la localisation possible des aires de recharge du système thermo minéral. Une attention spéciale a été portée sur des traceurs isotopiques et sur leur utilité dans la définition du modèle des eaux thermo minérales, considérant (1) le gradient de distribution de ?18O; (2) la composition isotopique moyenne des eaux thermo minérales dans la région; et (3) l’estimation du volume d’eau de fusion de la neige comme source de recharge de la nappe à Serra da Estrela. La recharge de l’aquifère thermo mineral a lieu sur les zones les plus perméables du massif granitique, en liaison avec les principales structures tectoniques, alors que la recharge du système aquifère superficiel semble avoir lieu principalement sur les plateaux, une autre partie de la recharge pouvant avoir lieu sur les pentes de la vallée de la rivière Zêrere. Se realizaron, con un enfoque multidisciplinario, relevamientos geológicos, geomorfológicos, estructurales, hidrogeoquímicos e isotópicos en el Sistema de aguas subterráneas del Serra da Estrela (Portugal central) con el objeto de establecer / desarrollar un modelo conceptual de circulación del sistema termomineral de las Caldas de Manteigas. Se llevó a cabo un estudio detallado de la composición isotópica y geoquímica de la aguas superficiales (por ejemplo el Río Zêzere), aguas subterráneas someras (manantiales fríos diluidos), y aguas termominerales para caracterizar la distribución de isótopos en las aguas de esta región montañosa, y determinar el origen y posibles ubicaciones de recarga del sistema termomineral. Se puso especial atención a los trazadores isotópicos y su rol en la definición del modelo conceptual de las aguas termominerales, considerando: (1) el gradiente de fraccionamiento de ?18O; (2) la composición media isotópica de las aguas termominerales en la región; y (3) la estimación del derretimiento de nieve como una fuente de la recarga de agua subterránea en Serra da Estrela. La recarga del acuífero termomineral ocurre en las zonas más permeables de

Carreira, Paula M.; Marques, José M.; Espinha Marques, Jorge; Chaminé, Helder I.; Fonseca, Paulo E.; Santos, Fernando Monteiro; Moura, Rui M.; Carvalho, José M.



Valutazione in vitro di un sistema atraumatico per la rimozione della carie dentaria (In Vitro Evaluation of Non-Traumatic System for Dental Caries Removal).  

National Technical Information Service (NTIS)

After a short introduction on the evolution, epidemiology and removal methods of dental caries, the results of a study carried out to assess the mechanical performance of dentin-rebuilding interface on Carisolv treated samples are reported. Carisolv is a ...

R. Bedini P. Ioppolo S. Caiazza G. Formisano M. A. Bassi



AlteraÁªo de par‚metros quÌmicos do solo pela reaplicaÁªo superficial de calcÆrio no sistema plantio direto(1)  

Microsoft Academic Search

ñ†Surface lime application is becoming an usual practice for soil acidity correction in the established no-tillage system in Southern Brazil. The objective of this study was to evaluate the effects of lime reapplication, with and without incorporation into the soil on chemical characteristics of the liquid and solid phase, in the soil profile at different periods. A†field experiment was set

Ibanor Anghinoni


AVALIAÇÃO RADIOGRÁFICA DO DESVIO APICAL APÓS O PREPARO RADICULAR UTILIZANDO O SISTEMA PROTAPER Radiographic evaluation of apical deviation after root canal preparation using system ProTaper  

Microsoft Academic Search

The poupose of this study was to evaluate radiographically the presence of apical deviation after the root canal preparation performed whit manual instruments using manual files Flexofiles and mechanical-rotary system Protaper. For this study, it was used thirty mesiovestibular roots of first superior human molars extracted. They had their curvature degrees determined performing to distribute them in 2 groups, so

Fábio Duarte; Celso Kenji Nishiyama; Renata Pardini Hussne; Renato de Toledo


Utilización de un sistema de derivación fecal en una paciente que desarrolla una fascitis necrotizante de la zona génito-perineal en una unidad de traumatología  

Microsoft Academic Search

Necrotizing fasciitis is a severe infection of the subcutaneous tissue, with a higher mortality if treatment is not adequate. Nursing care can be fundamental in obtaining a good outcome of the healing process. We present a case of an 80 year-old diabetic patient admitted to our orthopaedic surgery unit as consequence of a screw displacement in her hip. She was

Ana Craviotto Vallejo; Raquel Guzmán Carrasco; María Antonia Martín Fernández



System for Stabilization and Pointing of a Stratospheric Balloon-Borne Telescope Sistema Para Estabilizacao E Apontamento de Telescopio Embarcado Em Balao Aestratosferico.  

National Technical Information Service (NTIS)

A control system for pointing and stabilization of an infrared radiometer to be flown in stratospheric balloon missions was developed and built. This system permitted the azimuth stabilization and orientation of the entire scientific platform, on which al...

P. D. A. Borges C. C. Ghizoni C. D. O. Lino



Tracking and Treating Mobile Populations. The TB Net System. Migrant Clinicians Network Monograph Series. = El Sistema de Red para la TB.  

ERIC Educational Resources Information Center

A comprehensive tracking and referral network that helps provide continuity of care for mobile populations with active tuberculosis (TB) or TB infection is considered essential for effective treatment of TB. However, the interstate referral system that exists between state health departments has been highly inefficient for serving migrant…

Migrant Clinicians Network, Inc., Austin, TX.


Sistema de cúmulos globulares de la galaxia lenticular NGC 6861: en busca de indicios sobre la formación de las S0s.  

NASA Astrophysics Data System (ADS)

We present a preliminar photometric study of the globular cluster system (GCS), associated to the lenticular galaxy (S0) NGC 6861, which is located in a low density environment (d˜31.8 Mpc). It is based on GEMINI/GMOS images (GS-2010B-Q-2: PI Lilia P. Bassino) in the filters g', r', i' of three fields, one of them centered in the galaxy. We find a large number of GCs candidates and detect the presence of at least two sub-populations of GCs (``blue''/metal-poor and ``red''/metal-rich). The spatial distribution of ``red'' candidates presents a higher concentration toward the galaxy (associated to the bulge?), while the distribution of ``blue'' candidates is more homogeneus over the three fields (associated to the halo?). In the color-magnitud diagram, the ``blue'' GC candidates show a possible mass-luminosity relation, known as ``blue-tilt'', probably detected for the first time in a lenticular galaxy. FULL TEXT IN SPANISH

Escudero, C. G.; Faifer, F. R.; Bassino, L. P.; Calderón, J. P.; Caso, J. P.


Detecao, Aquisicao e Demodulacao de Sinais em um Sistema de Comunicacao Comacesso Aleatorio (Detection, Acquisition and Signal Demodulation in a Communication System with Random Access).  

National Technical Information Service (NTIS)

The development of a signal processor for the Data Collecting System of the first Brazilian Complete Space Mission is presented. The signals from the data collecting platforms are random both in time and frequency, and are spread over a band of 24 kHz. Th...

L. C. Pacolasobrinho



Sorbate destruction and non-enzymatic browning in model aqueous systems Destruccion de sorbatos y pardeamiento no enzimático en sistemas modelo acuosos  

Microsoft Academic Search

The effect of system composition on sorbate destruction and sensory damage due to non-enzy matic browning was studied in aqueous model systems with a water activity (aw) of 0.91 and a pH of 5.0-6.0. The rate constants of sorbate destruction could be described by first order kinetics and those from non-enzymatic browning by zero order kinetics. Both reactions were found

C. A. Campos; S. M. Alzamora; L. N. Gerschenson



Castración de vacas: Una alternativa para mejorar los sistemas de engorde Cows castration: An alternative to improve body weight gain systems  

Microsoft Academic Search

The aim of this work was to analyze the changes in the increase of body weight, meat-bone-fat relation, carcass weight, fat infi l- tration in the muscular mass and blood levels of triiodothyroxine induced by ovariectomy. Two different experiments were done in different fi elds of Argentina, A) young cows, B) old cows. Each experimental group was randomly divided into

Guillermo Edgardo Ashworth; Luis Alberto Poloni; Héctor Fernando Gauna



Sistema nakopleniya, upravleniya i kontrolya spektrometra NSVR v standarte VME. (A VME based accumulation, control and supervising system for the for the NSHR spectrometer).  

National Technical Information Service (NTIS)

An automation system for the neutron spectrometer with high resolution based on a modular VME computer is presented. The main electronic parts of the system described are: a time-of-flight accumulation system with 16384 time channels for 32 detectors, a f...

Zen En Ken N. I. Isakov A. S. Kirilov M. L. Korobchenko A. I. Ostrovnoj



Rendimentos de cortes da carcaça, características da carne e componentes do peso vivo em cordeiros terminados em três sistemas de alimentação  

Microsoft Academic Search

This study was carried outto evaluate the carcass physical composition, meat characteristics and the component conditions, non carcass live weight of lambs finished in different feeding systems. Sixteen lambs (Texel x Ile de France) were used and ramdomly allotted with their mothers, 24 hours after their birth, to three treatments: NSP - Natural supplemented pasture, RP - Ryegrass pasture (Lolium

Cleber José Tonetto; Cleber Cassol Pires; Liziany Müller; Marta Gomes da Rocha; José Henrique Souza da Silva; Rafael Batista Medeiros Frescura; Carlos Júnior Kippert



Sistema de enfriamiento con agua para hornos de sinterizado de pastillas de combustible nuclear. (Water cooling system for sintering furnaces of nuclear fuel pellets).  

National Technical Information Service (NTIS)

This work has as a main objective to develop a continuous cooling water system, which is necessary for the cooling of the sintering furnaces. This system is used to protect them as well as for reducing the water consumption, ejecting the heat generated in...



Sistema de dosimetria ambiental basado en LiF : Mg, Ti (LTD-100). (Environmental dosimetry system based on LiF : Mg, Ti (TLD-100)).  

National Technical Information Service (NTIS)

The report presents the various tests carried out to the characterize a thermoluminescence environmental dosimetry systems, using the phosphor LiF:Mg,Ti (TLD-100) in chip form. The holder has been specifically designed in order to obtain simplicity in the...

J. C. Saez



Edades y metalicidades de cinco cúmulos estelares proyectados en dirección a la Nube Menor de Magallanes: implicaciones sobre los procesos de formación y evolución de estos sistemas  

NASA Astrophysics Data System (ADS)

Washington photometry of the 5 star clusters Lindsay 32, Lindsay 38, Kron 28, Kron 44 and Lindsay 116 and their surrounding fields located towards the Small Magellanic Cloud (SMC) is presented for the first time. From the color-magnitude diagrams, cleaned from field stars contamination, the cluster and SMC field reddenings, ages and metallicities are determined. The ages - derived from the difference in the T1 magnitude betweem the giant clump and the Main Sequence turnoff point - vary between 2 and 6 Gyr, and the metallicities ([Fe/H]) between -1.65 and -1.10. Lindsay 116 is located closer to the Large Magellanic Cloud (LMC) than to the SMC and its fundamental parameters suggests a higher probability of belonging to the LMC. The results obtained in this work, combined with previous estimates of age and metallicity for other seven clusters, allow us to draw the following conclusions: (1) There does not exist an age-position relation in the SMC, but a age-metallicity one. (2) The chemical enrichment in the SMC has been very efficient during the last 5 Gyr. (3) The SMC clusters formation and evolution can be better represented by a bursting star formation process than by a continuum star formation mechanism.

Piatti, A. E.; Santos, J. F. C.; Clariá, J. J.; Bica, E.; Sarajedini, A.; Geisler, D.


Dozimetrichna sistema tip RFL-PP za individualen i obsht radiatsionen kontrol. (Radiophotoluminescent dosimetric system for personal and overall radiation control).  

National Technical Information Service (NTIS)

An experimental RPL-SC dosimetric system for measurement of absorbed doses in persons exposed to mixed gamma- and neutron field over 1 mGy has been created. The measuring principle is based on the radiophotoluminescence (RPL) and on the impact of fast neu...

M. G. Khristova



Hipertensão arterial sistêmica: o que nos dizem os sistemas brasileiros de cadastramentos e informações em saúde Systemic Arterial Hypertension: what do brazilian register and information systems say  

Microsoft Academic Search

The hypertension is configured as an important problem of public health in Brazil and the world. Estimates indicate that its prevalence is increasing and its impact in the po- pulations will be still more harmful in the next years. The periodical analysis of the information about hypertension is of major importance for health policy makers. Thus, the aim of this

Alexandra Crispim Boing; Antonio Fernando Boing


Caracterizacion de un sistema de dosimetria personal termoluminiscente (UD-710A, UD-802, UD-875 Panasonic). (Characterization of a thermoluminiscence personnel dosimetry system).  

National Technical Information Service (NTIS)

Various tests carried out to characterize a Thermoluminiscence Personnel Dosimetry Automatic System, based on the optical heating of amultielement dosemeter are presented. The dosemeter consists of Lithium Borate (Copper) and Calcium Sulphate (Thallium) p...

C. Vazquez J. C. Saez T. Labarta



Evaluacion de productos informaticos para el Sistema de Adquisicion de Datos del TJ-II. (Software package evaluation for the TJ-II Data Acquisition System).  

National Technical Information Service (NTIS)

The TJ-II Data Acquisition System (DAS) has to provide a user interface which will allow setup for sampling channels, discharge signal visualization and reduce data processing, all in run time. On the other hand, the DAS will provide a high level software...

C. Cremy E. Sanchez A. Portas J. Vega



Distribución espacio-temporal de hormigas en un gradiente de luz, dentro de un sistema agroforestal de café, en Turrialba, Costa Rica  

Microsoft Academic Search

Temporal and spatial distribution of ants in a light gradient, in a coffee agroforestry system, Turrialba, Costa Rica. Shade trees are frequently present in coffee (Coffea arabica L.) agroforestry systems of Mesoamerica. These systems can harbor a rich entomofauna, including ants, which could be predators of key pests in these systems. However, the role of shade on the distribution and

Edgar H. Varón; Paul Hanson; John T. Longino; Olger Borbón; Manuel Carballo; Luko Hilje



Microsoft Academic Search

The objective of this study is to verify if there are influences on subjective aspects of the organizational actors involved in an ERP system implementation. With this purpose, a case study in a food company located in Vila Velha, Espírito Santo was carried out. The implementation of the SAP R\\/3 ERP system was initiated in 1999. The data was collected

Renata Gomes de Jesus; Marilene Olivier; Ferreira de Oliveira


Control de un sistema caotico mediante modulacion de un parametro de control. (Controlling a Chaotic System through Control Parameter Self-Modulation).  

National Technical Information Service (NTIS)

A method for obtaining active control of a chaotic system based on the modulation of a control parameter by adding to it a small perturbation proportional to one output signal is proposed. From a theoretical point of view, chaos can be stabilized in the f...

I. Pastor



Sistema de Telemetria E Telecomandos de Baixo Custo Para Medicao Remota de Grandeza Fisicas (Low Cost Telemetry and Telecommand System for Remote Measurement of Magnitude Character).  

National Technical Information Service (NTIS)

The design is presented of a telemetry and telecommunication system for the remote measurement of lab experiments. It allows the interaction of equipment that stand on an Air Bearing table with other lab equipment. It is possible to use it in situations i...

P. G. Milani J. F. Ribeiro



Analisi econometrica delle preferenze dei consumatori: un sistema di spesa lineare applicato all'energia. (Econometrics analysis of consumer behaviour: a linear expenditure system applied to energy).  

National Technical Information Service (NTIS)

In economics literature the expenditure system specification is a well known subject. The problem is to define a coherent representation of consumer behaviour through functional forms easy to calculate. In this work it is used the Stone-Geary Linear Expen...

C. Giansanti V. Ferrari



Reforma de sistemas de servicios de salud y equidad en América Latina y el Caribe: algunas lecciones de los años 80 y 90  

Microsoft Academic Search

This essay proposes a review of the issues of equity and reform in Latin America and the Caribbean in the context of changes in recent decades, emphasizing the discussion of health systems reform. The economic, political, and social context prevailing in the critical 1970s exten- sively favored budget cuts for public expenditures, cost containment, changes in the health sector power

Celia Almeida



Estado actual y recomendaciones sobre la utilización de los sistemas de monitorización continua de glucosa en niños y adolescentes con diabetes mellitus tipo 1  

Microsoft Academic Search

Glucose monitoring methods have made great advances in the last decade with the appearance of the continuous glucose monitoring systems (CGMS) that measure the glucose levels in the interstitial liquid, providing information about glucose patterns and trends, but do not replace the self-monitoring of capillary glucose.Improvement in diabetes control using the CGMS depends on the motivation and training received by

M. Torres Lacruz; R. Barrio Castellanos; B. García Cuartero; A. Gómez Gila; I. González Casado; F. Hermoso López; C. Luzuriaga Tomás; M. Oyarzabal Irigoyen; I. Rica Etxebarria; M. Rodríguez Rigual




Microsoft Academic Search

The aim of the present work is to present the situation of Quality of Life assessment in lung cancer. Quality of Life evaluation is quite useful in clinical practice and in clinical trials with this disease. Nowdays, there is a deba- te on the treatment of lung cancer in which Quality of Life assessment has a key role. The EORTC

Juan Ignacio Arraras; Enrique Martínez; Maite Martínez




Microsoft Academic Search

During the last years, the development of the Systems of Information have revolted the methods of jobs realized until today, as in the private interprise as in the administration. Geo- graphic Information Systems (GIS), besides to be able to represent georrefered geographics dates, they are able to realice spatial analysis, which offer great possibilities in many apli- cations. This article

Javier Navarro Luna; Juan Sánchez del Río



Microsoft Academic Search

This paper describes a technological system developed to register the behavior of tennis and wheelchair tennis players in a return to service situation. This system is applicable as much in game situation (3 dimensions) as in laboratory, through a multimedia projection (2 dimensions). The study of the perceptive and motor components, to maximize the ecological validity of the experimental protocols,


Espalhamento elastico de deuteron num sistema de tres corpos com interacao Coulombiana. (Elastic scattering of deuteron in three-body system with Coulomb interaction).  

National Technical Information Service (NTIS)

The three-body formalism with coulomb interaction proposed by Alt, Sandhas and Ziegelmann is used in the calculation of the elastic deuteron-nucleus differential cross section, when the total energy of the three-body system is below the deuteron break-up ...

M. H. P. Martins



Sistema microcomputadorizado de sonda nuclear para avaliacao da funcao ventricular esquerda. (Microcomputerized system of nuclear probe for left ventricular function evaluation).  

National Technical Information Service (NTIS)

In this work, it is presented the development of a system, consisting in a nuclear probe and a 16 bits microcomputer, for left ventricular function (LVF) monitoring and analysis. Previously used in renal and thyroid studies, the nuclear probe, 2''x2''NaI(...

R. M. V. Piva



Evaluacion Financiera de dos sistemas de riego, goteo y gravedad en el cultivo de caña de azucar en Zapotiltic, Jalisco, Mexico  

Microsoft Academic Search

Faced with the imminent opening up of the trade in México in 2008, cultivation sugar cane (Sacchrum spp.) It has a strong competitive pressure from other producing countries that are operating with cost and low prices. Hence the need to seek production alternatives that could improve the profitability and competitiveness of this crop. For this propose was raised in this

Guadalupe Torres Sanchez; Victor Hugo Prado Vazquez; Ma. Patricia Rivera Espinoza




Microsoft Academic Search

Ameliorization of soil acidity with Ca and Mg on the development of peach palm root system at the pre-nursery growth stage. The effect of ameliorization of soil acidity with different sources of Ca and Mg on the initial development of the root system of peach palm was evaluated under nursery conditions. Soils classified as Andisol and Ultisol were used, as

Rafael E. Salas; Thomas J. Smyth; Danilo Alpízar; Jimmy Boniche; Alfredo Alvarado; Anthony Rivera; Nota Técnica



EFICIÊNCIA PRODUTIVA DE EMPRESAS DA INDÚSTRIA DE ALIMENTOS NO BRASIL Grupo de Pesquisa: Estrutura, Evolução e Dinâmica dos Sistemas Agroalimentares e Cadeias Agroindustriais  

Microsoft Academic Search

Resumo: A indústria de alimentos no Brasil é um setor de g rande importância para a economia brasileira com poucos estudos publicados quanto ao seu desempenho operacional. Este trabalho avalia a eficiência relativa (técnica e de escala) de uma amostra de empresas de diferentes segmentos desta indústria, utilizando-se para tanto o Método DEA. Os segmentos analisados foram: Conglomerados Alimentícios; Óleos

Apresentação Oral-Estrutura; OSCAR TUPY


Una controversia historica al servicio de una situacion de aprendizaje: una reconstruccion didactica basada en Dialogo sobre los dos maximos sistemas del mundo de Galileo  

Microsoft Academic Search

It is difficult for the common sense to admit that an object dropped from the top of the mast of a ship moving at a constant velocity falls down at the bottom of the mast because it keeps inside the horizontal movement of the ship. This difficulty is similar to the one faced by early scientists from the pre-classical science

Cecile de Hosson



Una controversia historica al servicio de una situacion de aprendizaje: una reconstruccion didactica basada en Dialogo sobre los dos maximos sistemas del mundo de Galileo  

Microsoft Academic Search

It is difficult for the common sense to admit that an object dropped from the\\u000atop of the mast of a ship moving at a constant velocity falls down at the\\u000abottom of the mast because it keeps inside the horizontal movement of the ship.\\u000aThis difficulty is similar to the one faced by early scientists from the\\u000apre-classical science

Cecile de Hosson



Sistema de adquisicion y monitoreo de datos para el acelerador de electrones Pelletron. (Data acquisition system for the Pelletron electron accelerator).  

National Technical Information Service (NTIS)

In this work, a system is developed that allows to know and view of immediate manner the conditions occurred during the operation of the Pelletron. This is carried out by means of the design of a data acquisition system which displays in graphic form, in ...

O. Flores



Analise probabilistica do consumo de combustivel num sistema hidrotermico com tarifacao marginalista. (Probabilistic analysis of fuel consumption in the hydrothermal system with marginal fixation of tariffs).  

National Technical Information Service (NTIS)

A simulation model, that determining the distribution function of the coal consumption from Chile Thermal Stations was developed, consisting in a tool for taking of a decision of coal purchase from Chilectra Generation Stations. It was applied for analysi...

I. Alarcon J. C. Olmedo



SMD286: Processador para Sistemas Multiprocessador com Memoria e Disco (SMD286: A Microcomputer Board for Multiprocessor Systems with Memory and Disk Storage).  

National Technical Information Service (NTIS)

The thesis describes the architecture of a microcomputer board for multiprocessor systems, based on the Intel 80286 microprocessor. The SMD286 processor evolves from the need to get the SMD architecture to support multi-user development environments and f...

S. P. M. Ferreira



Fenologia reprodutiva, polinização e sistema reprodutivo de Sophora tomentosa L. (Leguminosae - Papilionoideae) em restinga da praia da Joaquina, Florianópolis, sul do Brasil  

Microsoft Academic Search

Reproductive phenology, pollination and reproductive system of Sophora tomentosa L. (Leguminosae- Papilionoideae) on coastal sand dunes of Joaquina beach, Florianópolis, southern Brazil. The shrub Sophora tomentosa flowers from the month of October to June. The fructification begins soon after the start of the flowering period and continues up to the next flowering. The anthesis takes place during the day, and

Elisa Maria Lisboa Nogueira


Aplicação de um sistema baseado em conhecimento e lógica fuzzy para o mapeamento da fragilidade ambiental em relação às atividades florestais  

Microsoft Academic Search

The objective of this study was to determine and map the levels of environmental fragility considering the physical aspects of soil and implementation of silvicultural practices in an area with planting of Pinus taeda L. The analysis included two groups of variables: \\

Lorena Stolle


Avaliacao dos sistemas de distribuicao de energia eletrica: periodo 1984/89. (Evaluation of electric power distribution systems: period 1984/89).  

National Technical Information Service (NTIS)

The historical evolution of electric power distribution systems in Brazil, during 1984 to 1989 is described, showing the consumer market with the physical expansion of Distribution Networks and the results of quality from the services made by the companie...

W. A. Britto Filho V. G. Pinto



Evite los problemas de la diabetes: Mantenga sano el sistema nervioso (Prevent Diabetes Problems: Keep Your Nervous System Healthy, Number 6 in a Series of 7).  

National Technical Information Service (NTIS)

Too much glucose (sugar) in the blood for a long time can cause diabetes problems. This high blood glucose (also called blood sugar) can damage many parts of the body, such as the heart, blood vessels, eyes, and kidneys. Heart and blood vessel disease can...




Microsoft Academic Search

Performance of an agricultural tractor as a function of tillage system and load. II. Fuel consumption and motion resistance The interaction between wheel slip and motion resistance with the soil negatively affects the engine performance of agricultural tractors thus influencing their energy requirements. The objective of this trial was to determine the tractor motion resistance and fuel consumption under different

Maiby Pérez



Tracking and Treating Mobile Populations. The TB Net System. Migrant Clinicians Network Monograph Series. = El Sistema de Red para la TB.  

ERIC Educational Resources Information Center

|A comprehensive tracking and referral network that helps provide continuity of care for mobile populations with active tuberculosis (TB) or TB infection is considered essential for effective treatment of TB. However, the interstate referral system that exists between state health departments has been highly inefficient for serving migrant…

Migrant Clinicians Network, Inc., Austin, TX.


Distribución de eufáusidos en el sistema de surgencia frente a la península de Mejillones (23°S) asociada a condiciones previas y durante El Niño 1997-98  

Microsoft Academic Search

Euphausiids are abundant, although little studied components of the zooplancton in the Humboldt Current ecosystem. For instance, the effect that large scale ocean variability may exert on their population dynamics, abundance and distribution is unknown. In this work, based on 2-year time series data and two spatial surveys on December 1996 and July 1997, the distribution of euphausiids in coastal

Diego Fernández; Rubén Escribano; Pamela Hidalgo



Funcionalidade de sistemas colinergicos em ratos previamente tratados com triiodotironina. (Function of Colinergic systems in rats pre-treated with triiodothyronine).  

National Technical Information Service (NTIS)

In order to investigate the influence of experimental hyperthyroidism on cholinergic activity, rats were injected daily, during 1, 5, 19 or 20 days, with triiodothyronine (0 to 100 ug/kg, s.c.). The hiperthyroidism was evaluated by the decrease of the bod...

O. M. S. Almeida



Validez del Sistema de Información para el Desarrollo de la Investigación en Atención Primaria (SIDIAP) en el estudio de enfermedades vasculares: estudio EMMA  

Microsoft Academic Search

Introduction and objectivesInformation in primary care databases can be useful in research, but the validity of these data needs to be evaluated. We sought to analyze the validity of the data used in the EMMA study based on data from the Information System for the Development of Research in Primary Care.

Rafel Ramos; Elisabet Balló; Jaume Marrugat; Roberto Elosua; Joan Sala; Maria Grau; Joan Vila; Bonaventura Bolíbar; Maria Garcia-Gil; Ruth Martí; Francesc Fina; Eduardo Hermosilla; Magdalena Rosell; Miguel Angel Muñoz; Daniel Prieto-Alhambra; Miquel Quesada


Antiviral activity and mode of action of extracts from neem seed kernel against duck plague virus in vitro1.  


Four fractions obtained from alcohol extracts of neem (Azadirachta indica) seed kernel by column chromatography were investigated for antivirus activity against the duck plague virus (DPV) in vitro. Duck embryo fibroblasts (DEF) infected with DPV were treated with the neem seed kernel extracts, and the effect of antivirus was judged by 3-(4,5)-dimethylthiahiazo (-z-y1)-3,5-di-phenytetrazoliumromide colorimetric method assay and direct immunofluorescence assay. The mode of action was tested by the plaque reduction assay. The results showed that fractions 1 to 3 were inactive. The median inhibitory concentration (IC(50)) of fraction 4 was 10.9 ?g/mL and inhibited the virus protein expression in the direct immunofluorescence assay. In the plaque reduction assay, fraction 4 could significantly reduce the number of plaques compared with the negative control (P < 0.01) in all modes of action. This study indicated that the fourth fraction obtained from neem seed kernel could improve the viability of infected cells, and reduce the cytopathic effects caused by DPV and the amount of the virus protein expressed in virus-infected cells. The antiviral activity works in the whole process of virus infecting the normal cells. PMID:23091135

Xu, J; Song, X; Yin, Z Q; Cheng, A C; Jia, R Y; Deng, Y X; Ye, K C; Shi, C F; Lv, C; Zhang, W



Epidemiology of Acute Viral Hepatitis in Italy: Results of the Surveillance through SEIEVA (Sistema Epidemiologico Integrato dell;Epatite Virale Acuta). (Epidemiologia della Epatiti Virali Acute in Intalia: Risultati della Sorveglianza Attraverso il SEIEVA (Sistema Epidemiologico Integrato dell'Epatite Virale Acuta).)  

National Technical Information Service (NTIS)

This report describes epidemiological changes in acute viral hepatitis in Italy in the past two decades. The hepatitis A virus circulation progressively decreased. The incidence of symptomatic hepatitis A is 1.1/100,000/year in interepidemic periods. Shel...

A. Mele E. Spada M. E. Tosti O. Zuccaro



Molecular cloning of grass carp (Ctenopharyngodon idellus) T-bet and GATA-3, and their expression profiles with IFN-? in response to grass carp reovirus (GCRV) infection.  


Both T-bet and GATA-3, Th1/Th2 lineage-specific transcription factors, play important roles in the development of T cells and Th1/Th2 differentiation. In this study, T-bet and GATA-3 genes were cloned from grass carp (Ctenopharyngodon idellus). The putative primary structure of the polypeptide deduced from the cDNA sequence of grass carp T-bet contained 608 aa, which possessed a T-box DNA binding domain. The putative primary structure of the polypeptide deduced from the cDNA sequence of grass carp GATA-3 contained 396 aa, which possessed two consensus zinc finger domains (C-X(2)-C-X(17)-C-X(2)-C). The YxKxHxxxRP motif, KRRLSA and LMEKs/n sequences were also conserved in this GATA-3. Phylogenetic analysis indicated that grass carp T-bet and GATA-3 group with their known counterparts with zebrafish T-bet and GATA-3 as the closest neighbor, respectively. RT-qPCR results showed that grass carp T-bet gene was highly expressed in head kidney, followed by spleen, and low expressed in gill, liver, kidney, and intestine, while GATA-3 gene was highly expressed in intestine, followed by spleen, and low expressed in gill, liver, kidney, and head kidney. Grass carp is one of the "four important domestic fish" in China and often infected by grass carp reovirus (GCRV). As yet, there is no evidence that T-bet and GATA-3 (Th1/Th2 subsets) are involved in anti-virus immune of teleost fish. In this study, by RT-qPCR, we analyzed the expression dynamics of grass carp T-bet and GATA-3 genes with IFN-? gene in response to GCRV infection for the first time. The expression dynamics showed that three genes might be crucially modulated by in vivo GCRV infection: (1) GCRV mainly induced a T-bet expression profile comparing to the GATA-3 expression, while the higher expression profiles of IFN-? correlated with the up-regulation of T-bet; (2) T-bet/IFN-? and GATA-3 expression changes suggest that in GCRV-infected grass carp, the common immune state of head kidney further heightens, whereas the common physiological state of intestine transforms to an anti-virus immune state. From this finding, we realize that GCRV mainly induces a Th1 response, and Th1 cell-mediated recognition mechanisms play very important roles in anti-virus cellular immune of grass carp. PMID:23108805

Wang, Lu; Shang, Na; Feng, Hong; Guo, Qionglin; Dai, Heping



Deep PDF parsing to extract features for detecting embedded malware.  

SciTech Connect

The number of PDF files with embedded malicious code has risen significantly in the past few years. This is due to the portability of the file format, the ways Adobe Reader recovers from corrupt PDF files, the addition of many multimedia and scripting extensions to the file format, and many format properties the malware author may use to disguise the presence of malware. Current research focuses on executable, MS Office, and HTML formats. In this paper, several features and properties of PDF Files are identified. Features are extracted using an instrumented open source PDF viewer. The feature descriptions of benign and malicious PDFs can be used to construct a machine learning model for detecting possible malware in future PDF files. The detection rate of PDF malware by current antivirus software is very low. A PDF file is easy to edit and manipulate because it is a text format, providing a low barrier to malware authors. Analyzing PDF files for malware is nonetheless difficult because of (a) the complexity of the formatting language, (b) the parsing idiosyncrasies in Adobe Reader, and (c) undocumented correction techniques employed in Adobe Reader. In May 2011, Esparza demonstrated that PDF malware could be hidden from 42 of 43 antivirus packages by combining multiple obfuscation techniques [4]. One reason current antivirus software fails is the ease of varying byte sequences in PDF malware, thereby rendering conventional signature-based virus detection useless. The compression and encryption functions produce sequences of bytes that are each functions of multiple input bytes. As a result, padding the malware payload with some whitespace before compression/encryption can change many of the bytes in the final payload. In this study we analyzed a corpus of 2591 benign and 87 malicious PDF files. While this corpus is admittedly small, it allowed us to test a system for collecting indicators of embedded PDF malware. We will call these indicators features throughout the rest of this report. The features are extracted using an instrumented PDF viewer, and are the inputs to a prediction model that scores the likelihood of a PDF file containing malware. The prediction model is constructed from a sample of labeled data by a machine learning algorithm (specifically, decision tree ensemble learning). Preliminary experiments show that the model is able to detect half of the PDF malware in the corpus with zero false alarms. We conclude the report with suggestions for extending this work to detect a greater variety of PDF malware.

Munson, Miles Arthur; Cross, Jesse S. (Missouri University of Science and Technology, Rolla, MO)



Caracterización de entornos y determinantes de la eficiencia en los sectores del cuero, el calzado y la marroquinería  

Microsoft Academic Search

Este estudio permite caracterizar al sector en Colombia en seis entornos principales e identificar los principales aspectos que marcan la diferenciaentre las empresas de calzado y marroquinería en cuero, ubicadas en el Área Metropolitana del Valle de Aburrá (Amva),1 seleccionadas a partir de una muestra representativa, y comparadas con otras ciudades del país. Adicionalmente, y lo más importante, ayuda a

David Tobón Orozco; Jorge Barrientos Marín


Relation of streams, lakes, and wetlands to groundwater flow systems  

NASA Astrophysics Data System (ADS)

Surface-water bodies are integral parts of groundwater flow systems. Groundwater interacts with surface water in nearly all landscapes, ranging from small streams, lakes, and wetlands in headwater areas to major river valleys and seacoasts. Although it generally is assumed that topographically high areas are groundwater recharge areas and topographically low areas are groundwater discharge areas, this is true primarily for regional flow systems. The superposition of local flow systems associated with surface-water bodies on this regional framework results in complex interactions between groundwater and surface water in all landscapes, regardless of regional topographic position. Hydrologic processes associated with the surface-water bodies themselves, such as seasonally high surface-water levels and evaporation and transpiration of groundwater from around the perimeter of surface-water bodies, are a major cause of the complex and seasonally dynamic groundwater flow fields associated with surface water. These processes have been documented at research sites in glacial, dune, coastal, mantled karst, and riverine terrains. Résumé Les eaux de surface sont parties intégrantes des systèmes aquifères. Les eaux souterraines interagissent avec les eaux de surface dans presque tous les types d'environnements, depuis les petits ruisseaux, les lacs et les zones humides jusqu'aux bassins versants des vallées des grands fleuves et aux lignes de côte. Il est en général admis que les zones topographiquement hautes sont des lieux de recharge des aquifères et les zones basses des lieux de décharge, ce qui est le cas des grands systèmes aquifères régionaux. La superposition de systèmes locaux, associés à des eaux de surface, à l'organisation régionale d'écoulements souterrains résulte d'interactions complexes entre les eaux souterraines et les eaux de surface dans tous les environnements, quelle que soit la situation topographique régionale. Les processus hydrologiques associés aux eaux de surface elles-mêmes, tels que des niveaux d'eau de surface saisonnièrement hauts et l'évaporation et la transpiration de l'eau souterraine à la périphérie des eaux de surface, sont les causes essentielles de la dynamique complexe et saisonnière des nappes associées aux eaux de surface. Ces processus ont été mis en évidence sur des sites de recherche dans des formations glaciaires, dunaires, littorales, fluviales et de karst couvert. Resumen Los cuerpos de aguas superficiales son partes integrales de los sistemas de flujo subterráneo. El agua subterránea interactúa con la superficial en prácticamente todo tipo de paisajes, desde pequeños torrentes, lagos y humedales, hasta grandes valles fluviales y costas. Aunque se suele asumir que las áreas topográficamente elevadas son zonas de recarga de aguas subterráneas, mientras las áreas topográficamente más bajas lo son de descarga, esto es cierto básicamente para los sistemas de flujo regional. Al superponer los sistemas de flujo local, asociados a los cuerpos de agua superficial, a las condiciones regionales, resultan interacciones complejas, y esto ocurre independientemente de su posición topográfica. Los procesos hidrológicos asociados con los propios cuerpos de agua superficial, como los niveles superficiales máximos estacionales y la evapotranspiración de agua subterránea en los perímetros de cuerpos superficiales, son una de las principales causas de la complejidad y de las variaciones dinámicas de las interacciones entre aguas subterráneas y superficiales. Estos procesos se han documentado en distintas zonas investigadas, incluyendo depósitos glaciares, dunas, áreas costeras, karsts y terrazas fluviales.

Winter, Thomas C.



PubMed Central

Preparative high-speed countercurrent chromatography (HSCCC) was successfully used for isolation and purification of caffeic acid from Eupatorium adenophorum Spreng with a solvent system composed of ethyl acetate-methanol-water at a volume ratio of 10:1:10, v/v. Using a preparative unit of the HSCCC centrifuge, about a 938 mg amount of the crude extract was separated, yielding 63.2 mg of caffeic acid at purity of 96.0%. Then, the anti-microbial and anti-virus drug caffeic acid (C9H8O4) was intercalated into layered double hydroxides for the first time by anion exchange under a nitrogen atmosphere. The product caffeic acid–LDH has been characterized by powder X-ray diffraction (XRD), Fourier transform-infrared (FT-IR), Scanning electron micrographs (SEM), indicating that the drug has been successfully intercalated into LDH.

Wei, Yun; Gao, Yali; Zhang, Kai; Ito, Yoichiro



Design, synthesis and antiviral activity studies of schizonepetin derivatives.  


A series of schizonepetin derivatives have been designed and synthesized in order to obtain potent antivirus agents. The antiviral activity against HSV-1 and influenza virus H3N2 as well as the cytotoxicity of these derivatives was evaluated by using cytopathic effect (CPE) inhibition assay in vitro. Compounds M2, M4, M5 and M34 showed higher inhibitory activity against HSV-1 virus with the TC50 values being in micromole. Compounds M28, M33, and M35 showed higher inhibitory activity against influenza virus H3N2 with their TC50 values being 96.4, 71.0 and 75.4 ?M, respectively. Preliminary biological activity evaluation indicated that the anti-H3N2 and anti-HSV-1 activities improved obviously through the introduction of halogen into the structure of schizonepetin. PMID:23965980

Bao, Beihua; Meng, Zheng; Li, Nianguang; Meng, Zhengjie; Zhang, Li; Cao, Yudan; Yao, Weifeng; Shan, Mingqiu; Ding, Anwei



[Advance in studies on anti-tumor activity of polysaccharides in latest five years].  


Polysaccharides widely exist in animals, plants, microorganisms, and possess various biological activities including anti-tumor, anti-virus, anti-oxidant and immunomodulatory. Polysaccharides shows notable anti-tumor activity and less toxicity, and becomes a hotspot in the studies of anti-tumor drugs. Therefore, there is huge potential for developing polysaccharides into a novel antitumor medicine. This article summarized polysaccharides derived from animals, plants, microorganisms which have significant antitumor effect in the latest 5 years; findings indicate that polysaccharides show the anti-tumor effect directly by inducing tumor cell apoptosis and indirectly as an immunoenhancement. This article also looks into the future of studies on anti-tumor activity of polysaccharides. PMID:23944021

Lin, Jun; Li, Ping; Chen, Kao-Shan



Global dynamics of a novel multi-group model for computer worms  

NASA Astrophysics Data System (ADS)

In this paper, we study worm dynamics in computer networks composed of many autonomous systems. A novel multi-group SIQR (susceptible-infected-quarantined-removed) model is proposed for computer worms by explicitly considering anti-virus measures and the network infrastructure. Then, the basic reproduction number of worm R0 is derived and the global dynamics of the model are established. It is shown that if R0 is less than or equal to 1, the disease-free equilibrium is globally asymptotically stable and the worm dies out eventually, whereas, if R0 is greater than 1, one unique endemic equilibrium exists and it is globally asymptotically stable, thus the worm persists in the network. Finally, numerical simulations are given to illustrate the theoretical results.

Gong, Yong-Wang; Song, Yu-Rong; Jiang, Guo-Ping





Preparative high-speed countercurrent chromatography (HSCCC) was successfully used for isolation and purification of caffeic acid from Eupatorium adenophorum Spreng with a solvent system composed of ethyl acetate-methanol-water at a volume ratio of 10:1:10, v/v. Using a preparative unit of the HSCCC centrifuge, about a 938 mg amount of the crude extract was separated, yielding 63.2 mg of caffeic acid at purity of 96.0%. Then, the anti-microbial and anti-virus drug caffeic acid (C(9)H(8)O(4)) was intercalated into layered double hydroxides for the first time by anion exchange under a nitrogen atmosphere. The product caffeic acid-LDH has been characterized by powder X-ray diffraction (XRD), Fourier transform-infrared (FT-IR), Scanning electron micrographs (SEM), indicating that the drug has been successfully intercalated into LDH. PMID:20454592

Wei, Yun; Gao, Yali; Zhang, Kai; Ito, Yoichiro



Collecting Autonomous Spreading Malware Using High-Interaction Honeypots  

NASA Astrophysics Data System (ADS)

Autonomous spreading malware in the form of worms or bots has become a severe threat in today's Internet. Collecting the sample as early as possible is a necessary precondition for the further treatment of the spreading malware, e.g., to develop antivirus signatures. In this paper, we present an integrated toolkit called HoneyBow, which is able to collect autonomous spreading malware in an automated manner using high-interaction honeypots. Compared to low-interaction honeypots, HoneyBow has several advantages due to a wider range of captured samples and the capability of collecting malware which propagates by exploiting new vulnerabilities. We validate the properties of HoneyBow with experimental data collected during a period of about nine months, in which we collected thousands of malware binaries. Furthermore, we demonstrate the capability of collecting new malware via a case study of a certain bot.

Zhuge, Jianwei; Holz, Thorsten; Han, Xinhui; Song, Chengyu; Zou, Wei


Gossypol--a polyphenolic compound from cotton plant.  


Gossypol (C(30)H(30)O(8)) is a polyphenolic compound derived from the cotton plant (genus Gossypium, family Malvaceae). The presence of six phenolic hydroxyl groups and two aldehydic groups makes gossypol chemically reactive. Gossypol can undergo Schiff base formation, ozonolysis, oxidation, and methylation to form gossypol derivatives. Gossypol and its derivatives have been the target of much research due to their multifaceted biological activities including antifertility, antivirus, anticancer, antioxidant, antitrypanosomal, antimicrobial, and antimalarial activities. Because of restricted rotation of the internaphthyl bond, gossypol is a chiral compound, which has two atropisomers (i.e., (+)- and (-)-gossypol) that exhibit different levels of biological activities. This chapter covers the physiochemical properties, analyses, biological properties, and agricultural and clinical implications of gossypol. PMID:19878861

Wang, Xi; Howell, Cheryl Page; Chen, Feng; Yin, Juanjuan; Jiang, Yueming



Logistic model for determining factors associated with HIV infection among blood donor candidates at the Funda??o HEMOPE  

PubMed Central

Objective To determine factors associated with HIV infection in blood donor candidates in Recife, Brazil. Methods A transversal study was performed of 106,203 blood donor candidates found eligible by the routine clinical screening process in the blood bank in Recife of the Fundação de Hematologia e Hemoterapia de Pernambuco (HEMOPE) in the period from January 1998 to November 2003. Additional indirect immune and western blot confirmation tests for HIV infection were performed and the candidates were classified as HIV positive or negative. The Chi-squared test and stepwise multiple logistic regression were conducted to examine any association between HIV infection and age, gender, place of residence, schooling, number of donations and serological tests for core hepatitis B antigen virus (anti-HBc), the hepatitis C antivirus (anti-HCV), human T-type antivirus lymph cells (anti-HTLV 1 and 2), serological tests for syphilis (VDRL) and the hepatitis B virus surface antigen (HBsAg). Results In the observed sample, 0.204% of blood donor candidates were found to be HIV positive. Among the studied variables, the age, education level, residency, donation type, and serologic status for anti-HBc and VDRL tests were found to be associated with HIV infection. Conclusions The younger, spontaneous donor candidates living in the Recife metropolitan area with a low level of education and positive for anti-HBc and VDRL have an higher risk of HIV infection than the other candidates. Data such as these are useful to understand the dynamics of infection and to guide healthcare policies.

Queiroz, Niedja Maristone Barreto; Sampaio, Divaldo de Almeida; Santos, Eufrazio de Souza; Bezerra, Ana Cristina de Souza



[Clinical trials and intensive therapy of the swine flu (H1N1)].  


During the recent years there's a high index of the swine flu ? (H1N1) disease in the whole world. In Georgia it began to spread at the end of Autumn 2009. The aim of our study was to define clinical trials of the swine flu (H1N1) in patients of Republic Clinical Hospital in Batumi from 2009 to 2011 and to generalize the methods of treatment. In the hospital there were 94 patients suffering from the swine flu (H1N1) disease, 20 of which due to their critical situation of the disease were treated in the department of the intensive therapy. We studied case histories of 20 patients, who were undergoing treatment in the department of the intensive therapy by the generally acknowledged programme of study and monitoring due to their hard disease. Among these 20 patients 10 were women and 10 men. 10 patients died. The programme of intensive treatment consisted of infusive-transfusive therapy by the negative water balance, antivirus treatment (Tamiflu/Relenza), de-escalation antibiotic therapy, mechanic ventilation of lungs, aerosol therapy, plus symptom treatment. In 2011 there were fewer cases of the swine flu and the death rate compared to the earlier years. In 2011 of 25 patients only one patient died, but in 2009-2010 of 69 patients 7 patients died), which was conditioned by immunity development. The most frequently used regime of lung mechanic ventilation was BIPAR. In the first days antibiotic therapy is not defining. It is necessary to find more effective method of antivirus treatment. PMID:22392781

Nakashidze, I M; Tsintsadze, N G; Potskhishvili, Sh N; Dzhibladze, K M



Instituto Nacional de Electrification, Guatemala Load Dispatch Center and Global Communications Center. Feasibility report (Instituto Nacional de Electrificacion, Guatemala Centro Nacional de Despacho de Carga y Sistema Global de Comunicaciones). Export trade information  

SciTech Connect

The report presents the results of a feasibility study for the National Load Dispatch Center and Global Communications System Project in Guatemala. The project consists of a communication system which will provide Institute Nacional de Electrificacion (INDE) operations personnel direct voice access to all major power system facilities. In addition, a modern computer based load dispatch center has been configured on a secure and reliable basis to provide automatic generation control of all major interconnected generating plants within Guatemala.

Not Available



Sistema Informativo Nazionale per la Sorveglianza delle Esposizioni Pericolose e delle Intossicazioni: Casi Rilevati nel 2009. Quarto Rapporto Annuale. (National Informative System for Surveillance of Toxic Exposures and Poisonings: Cases Identified in 2009. Fourth Annual Report.)  

National Technical Information Service (NTIS)

In 2009, The National Informative System for Surveillance of Toxic Exposures and Poisonings (NIS-STEP) detected 46.303 cases of human exposure. About 44% of cases were aged less than 6 years. Male and female individuals were equally distributed. About 90%...

E. Urbani F. Davanzo F. Giordano G. Milanesi L. Cossa L. Settimi



Sistema Informativo Nazionale per la Soveglianza delle Esposizioni Pericolose e dell Intossicazioni: Casi Rilevati nel 2008. Terzo Rapporto Annuale. (National Informative System for Surveillance of Toxic Exposures and Poisonings: Cases Identified in 2008. Third Annual Report.)  

National Technical Information Service (NTIS)

In 2008, The National informative system for surveillance of toxic exposures and poisonings detected 47,278 cases of human exposure. About 44% of cases were aged less than 6 years. Male and female individuals were equally distributed. About 90% of exposur...

E. Urbani F. Davanzo F. Giordano G. Milanesi L. Cossa L. Settimi



Modificacion de la marcacion de eritrocitos autologos con Tc-99m para la evaluacion centellografica del sistema venoso profundo. (Modification of the labelling autologous erythrocytes with Tc-99m to scintigraphic evaluation of deep vein system).  

National Technical Information Service (NTIS)

The purpose of this was the modification of labelled autologous red blood cells in vivo/in vitro. Evaluation consisted in different combinations of Tc-99m radiopharmaceuticals as pyrophosphate (PYP) and stannous chloride (SnCl2), anticoagulants as heparin...

C. M. Quintero D. Y. Freire



AR-ISS: Sistema di Sorveglianza Dell'Antibiotico-Resistenza Basato su Laboratori Sentinella (2003-2005) (AR-ISS: Antibiotic Resistance Surveillance System Based on a Laboratory Network (2003-2005)).  

National Technical Information Service (NTIS)

The antibiotic resistance surveillance (AR-ISS) of the Istituto Superiore di Sanita (ISS, the National Institute of Health in Italy) was established to study the emergence and the spread of antibiotic resistance at a national level. The AR-ISS network was...

A. Pantosti F. D'Ancona M. Ciofi M. Monaco V. Alfonsi



INFLUNET: Sistema di Sorveglianza Sentinella delle Sindromi Influenzali in Italia. Rapporto Influenzale 2010-2011. (INFLUENT: A Sentinel Surveillance Network for Influenza Like Illness in Italy. Report for the Season 2010-2011).  

National Technical Information Service (NTIS)

The sentinel network is a valuable tool for describing the epidemiology of influenza in Italy. In addition, it provides information for defining the baseline in order to allow comparison in the future. Beginning from the flu season (2000-2001), sentinel s...



Estudo sobre as multiplas solucoes da equacao de Hartree-Fock-Roothaan para sistemas de camada fechada. (Study on the multiple solutions of the Martree-Fock-Roothaan equation for closed shell systems).  

National Technical Information Service (NTIS)

An analysis of the multiple solutions of the Hartree-Fock-Roothaan equation for closed shell systems is done. The meaning of these solutions is discussed as self-consistent solutions of the pseudo-eingen-value equation and a general method for obtaining t...

L. A. C. Malbouisson



Productividad primaria del fitoplancton en la zona eufótica del Sistema de la Corriente de California estimada mediante imágenes del CZCS Phytoplankton primary productivity in the euphotic zone of the California Current System estimated from CZCS imagery  

Microsoft Academic Search

We estimated phytoplankton primary productivity (PP) in the euphotic zone of the California Current System using chlorophyll concentration (Chl) from CZCS imagery. The area was divided into two regions, Southern California (SC) and Baja California (BC), with inshore and offshore subregions, and into two seasons, cool and warm. The Chl and PP values were in general higher and more variable

OA Barocio-León; R Millán-Núñez; E Santamaría-del-Ángel; A González-Silvera


Retos de la diversidad: el reconocimiento y aplicación de los sistemas de derecho indígenas ecuatorianos The Challenges of Diversity: Recognition and Application of the Legal Systems of Indigenous Ecuadorians  

Microsoft Academic Search

This text provides an analysis of the challenge represented by the legal systems of Ecuadorian indigenous nationalities since the 1998 Constitution was approved until today, and their rela- tion with the ordinary legal system. To that end, we undertake an approach to the period the 1998 Constitution was in force, up to 2008, the year in which the current Constitution



Observaciones sobre los efectos de inmunomodulación de Leishmania major en células del sistema inmune humano Observations on the effects of immunomodulation by Leishmania major on cells of the human immune system  

Microsoft Academic Search

the immuno-modulator effects of the blood parasites of the genus Leishmania were analyzed. Human macrophages were purified and infected with Leishmania major. NK cells were purified and co-incubated with L. major-infected macropha- ges. The presence of molecules of class-I major histocompatibility complex (MHC-I) was evaluated by immunocytochemical staining, and the survival of infected macrophages was analyzed by means of supravital

J. Rubén



Valoración pronóstica del carcinoma ductal infiltrante mamario en PAAF. Estudio comparativo de tres sistemas de graduación citológica Prognostic evaluation of invasive ductal carcinoma of the breast by fine needle aspiration biopsy. Comparative study of three cytological grading systems  

Microsoft Academic Search

SUMMARY We have evaluated three different systems of cytologic grading based in morphological parameters in order to define the Cytological Grade (CG) making a correlation with the Histological Grade (HG), Histological Cytological Grade (HCG) and the Histological Mitotic Index (HMI) in 366 FNA biopsies from surgical specimens of the breast without fixation diagnosed as invasive ductal carcinoma. The sensitivity and

Francisco Javier Torres Gómez; Luis Felipe Calle Cruz; Francisco Javier Torres Oliver


La utilidad de los sistemas de información geográfica en la predicción de la distribución regional de la tuberculosis bovina Usefulness of geographic information systems in predicting the distribution of bovine tuberculosis in Jalisco, Mexico  

Microsoft Academic Search

A growing need exists for low cost systems to predict the status of diseases within geographical regions. The purpose of this research was to evaluate the usefulness of geographic information systems (GIS) and geostatistical (i.e.: Kriging) methods in predicting the prevalence and distribution of bovine tuberculosis (BTB) in the state of Jalisco, Mexico, based on a sample of herds. Two-thousand

Horacio Zendejas Martínez; Leticia García Casanova; Gustavo Cruz Bello; Ana María Anaya Escalera; Gabriel Huitrón Márquez


Distribución de los receptores para el factor de crecimiento derivado de las plaquetas (PDGFR y PDGFR) en el sistema músculo-esquelético Distribution of the platelet-derived growth factor receptors (PDGFR y PDGFR) in the muscle-skeletal system  

Microsoft Academic Search

The patelet-derived growth factor (PDGF) is envolved in the development and in the pathogenesis of some diseases of the mus- cle-skeletal system. Nevertheless, the distribution of the PDGF re- ceptors, i.e. PDGFR y PDGFR, in bone, cartilage and skeletal muscles is poorly known. In this study we used Western-blot and inmunohistochemistry to analyze the distribution of both types of receptors


Tecnicas de Sensoriamento Remoto E Sistemas Geograficos de Informacoes No Estudo Integrado de Bacias Hidrograficas (Use of Remote Sensing and Geographic Information System Techniques in Integrated Studies of Watersheds).  

National Technical Information Service (NTIS)

This study was designed to assess the multitemporal patterns of soil loss at Ribeirao Bonito watershed State of Sao Paulo, Brazil. The potential of integrated use of remote sensing and GIS in environmental studies was evaluated. The applicability of the U...

A. G. Decastro



Desenvolvimento de um sistema de coincidencia para a medida absoluta da atividade de radionuclideos empregando detectores de barreira de superficie. (Development of a coincidence system for radio-nuclide standardization using surface barrier detectors).  

National Technical Information Service (NTIS)

A system for the standardization of alpha-gamma or electron-X radionuclide emitters has been developed in the present work. The system consists of one or two surface barrier detectors for alpha or electron detection which are coupled to thin-window NaI (T...

M. F. Koskinas



AVALIAÇÃO DE INDICADORES BIOLÓGICOS DE QUALIDADE DO SOLO SOB SISTEMAS DE CUL TIVO CONVENCIONAL E ORGÂNICO DE FRUT AS Evaluation of biological indicators of soil quality under conventional and organic fruit farming system  

Microsoft Academic Search

The aim of this paper was to evaluate biological indicators of soil quality under conventional and organic farming systems of fruits in Piauí state. Soil samples were collected in the projection area of plant canopies and in the row at a 0-10, 10-20 and 20- 40 cm depths in two areas: organic farming system with acerola orchards (SO), conventional farming

Deusiane Batista Sampaio; Ademir Sérgio; Ferreira de Araújo; Valdinar Bezerra dos Santos


Idades Th-U-PbT de Monazita e Geotermobarometria de Rochas Metapelíticas de Alto Grau do Sistema Orogênico Itabuna-Salvador-Curaçá, BA, Brasil: um Estudo em Microssonda Eletrônica  

Microsoft Academic Search

Electron microprobe Th-U-PbT dating of monazite was performed on aluminous gneiss samples from the northern Jacurici and southern Ilhéus areas of the Itabuna-Salvador-Curaçá Orogenic System. Studied samples are spinel-sillimanite-cordierite- garnet gneiss and corundum-spinel-sillimanite-garnet gneiss that equilibrated during a high temperature metamorphism at T-P conditions of about 835°C\\/6.9 kbar and 890°C\\/7.4 kbar, respectively. Microprobe ages of monazite in equilibrium with these

Silvio Roberto; Farias Vlach; Eliane Aparecida Del Lama


Calculo do custo marginal de producao de energia em sistemas hidrotermoeletricos levando em consideracao a rede de transmissao. (Marginal cost calculation of energy production in hydro thermoelectric systems considering the transmission system).  

National Technical Information Service (NTIS)

The alternatives for calculation of energy marginal cost in hydroelectric systems, considering the transmission one, was analysed, including fundamental concepts; generation/transmission systems, represented by linear power flow model; production marginal...

M. V. F. Pereira B. G. Gorenstin S. Alvarenga Filho



Um modelo computacional para determinacao de alternativas de expansao de custo minimo em planejamento de sistemas de transmissao. (A computational model for determining the minimal cost expansion alternatives in transmission systems planning).  

National Technical Information Service (NTIS)

A computational model for determining an economical transmission expansion plan, based in the decomposition techniques is presented. The algorithm was used in the Brazilian South System and was able to find an optimal solution, with a low computational re...

L. M. V. Pinto M. V. F. Pereira A. Nunes



Sistema di Sorveglianza PASSI (Progressi Delle Aziende Sanitarie per la Salute in Italia) (PASSI (Progressi Delle Aziende Sanitarie per la Salute in Italia): An Italian Behavioral Risk Factor System).  

National Technical Information Service (NTIS)

Lifestyle plays an important role in the development of non-communicable chronic diseases, which contribute significantly to the burden of disease in Europe. In 2006, the Centre for Disease Control and Prevention at the Italian Ministry of Health (MoH) en...

B. De Mei G. Fontana N. Binkin S. Baldissera V. Minardi




Microsoft Academic Search

The coffee benefit is a pollutant activity to the environment due to being a source of atmospheric emissions. The objective of this project was the development of a prototype of low cost, easy maintenance and operation, for atmospheric emissions control in the coffee improvement process. The operation of the prototype consists of the collection of the atmospheric emissi ons and

Aurélio Azevedo


Retrospecto da politica nuclear no Brasil e perspectivas de utilizacao de pequenas centrais nucleares - PCNs - no sistema eletrico brasileiro. (Nuclear policy retrospection in Brazil and forecasting for using of small nuclear power plants - SNPs - in the Brazilian electric system).  

National Technical Information Service (NTIS)

This thesis highlights the nuclear energy perspectives to regain a prominent place in the world energy mix, as a competitive and safe energy source. Just considering the current international changes in the nuclear power features in the developed countrie...

E. M. Santos



IMPLANTAÇÃO, MANEJO E UTILIZAÇÃO DO SISTEMA AGROFLORESTAL CERCAS VIVAS DE Gliricidia sepium (Jacq.) Steud. NA COSTA RICA (Establishment, management and utilization of agroforestry systems (Gliricidia sepium (Jacq.) Steud.), living fences, in Costa Rica  

Microsoft Academic Search

O melhor aproveitamento de agroecossiste mas pouco produtivos, para a racionalização no uso da terra e a identificação de espécies para usos múltiplos, que cumpram objetivos sócio-econômicos e ecológicos, são aspectos que justificam esse trabalho. Efetuou-se um levantamento, a nível de Costa Rica, com o intuito de codificar o conhecimento dos agricultores quanto aos fatores que influem na implantação, manejo

Amilton J. Baggio; Jochen Heuveldop


INVESTIGAÇÕES EM SISTEMAS DE SERVIÇOS DE SAÚDE COMO FERRAMENTA PARA O ALCANCE DE PROGRAMAS DE CONTROLE DA HANSENÍASE MAIS EFETIVOS NO B RASIL* Health systems research training as a tool for more effective Hansen's disease control programmes in Brazil  

Microsoft Academic Search

RESUMO No Brasil, a hanseníase permanece como um importante problema de saúde pública. Embora um grande progresso tenha sido obtido nos Programas de Controle da Hanseníase (PCH), em todos os níveis do governo nos últimos 20 anos, algumas ações não foram potencializadas. O motivo: lacunas de informação relacionadas a áreas específicas da doença, exacerbadas pela ausência de instrumentos apropriados para

Alberto Novaes Ramos Jr; Jorg Heukelbach; Marcia Gomide; Pieter A. M. Schreuder



Microsoft Academic Search

The profitability of a production system of oyster mushrooms was evaluated under conditions of greenhouse with a surface of 112 m2 located in San Salvador Chachapa, pertaining to the municipality of Amozoc de Mota in the state of Puebla. The indicators of economic evaluation were used: net present value (NPV), relation benefit-cost (B\\/C), relation net benefitinvestment (N\\/K) and internal rate

Omar Romero Arenas; J. Manuel Barrios Diaz; A. Macias Lopez; A. Simon Baez; A. Ibanez Martinez; F. Juarez Huerta




Microsoft Academic Search

The work go by to investigate advances in the water treatment supply at Sludge Blanket Flocculator System (SFML), therefore is verified that the traditional superficial water treatment plant demand many operational contingent. Objectifying thus, the SFML optmization, onwards the work of the studies at Jar-Test on hydraulical correlations, based on the gradient of velocity with a SFML pilot scale bulded

T. L. Cavazzana; T. Matsumoto


Efectividad del sistema de regulacion mecanico del primer bloque de la central electronuclear de Juragua. (Effectiveness of the mechanical regulation system of the First Block Juragua Nuclear Power Plant).  

National Technical Information Service (NTIS)

In this report the most important calculated values of the control rods integral and differential effectivity are shown for the Juragua Nuclear Power Plant (First reactor-turbine unit), at the beginning and the end of the first and seventh cycle, supposin...

C. R. Garcia Hernandez P. Diaz



O ciclo do café durante a República Velha: uma análise com a abordagem de dinâmica de sistemas [Coffe cycle during the Old Republic: analysis with a system dynamics approach  

Microsoft Academic Search

The purpose of this work is to perform a systemic analysis of coffee production in Brazil in the period 1900-1930. The motivation to use system dynamics is that such methodology seems especially suitable to model processes subject to dynamic complexity, such as commodity cycles. Firstly, it will be shown that modeling and simulating the dynamics of coffee production in Brazil

Thiago Caliari; Newton Paulo Bueno



Study of a Measuring System for the Characterization of the Physical Mechanisms Causing Discrimination Loss Between Two Orthogonally Polarized Transmission Carriers Studio di UN Sistema di Misura Per la Caratterizzazione Dei Meccanismi Fisici Causanti Degradazione di Discriminazione Tra Polarizzazione Ortogonali.  

National Technical Information Service (NTIS)

A study of a measuring system to characterize depolarization of millimetric waves at 30 Ghz is presented. The theoretical accuracy limits required for measuring the interactions between non-spherical raindrops and coherent waves are discussed. The perform...

D. Maggiori P. Migliorini A. Paraboni



Analise exergetica do sistema de refrigeracao do acelerador de particulas Pelletron-Linac da Universidade de Sao Paulo. (Exergetic analysis of refrigeration system of the Pelletron-Linac particle accelerator of the University of Sao Paulo).  

National Technical Information Service (NTIS)

The Pelletron-Linac accelerator of the University of Sao Paulo will use the existing electrostatic Pelletron accelerator as an injector for the linear superconducting accelerator (Linac), to increase the acceleration of the particles. The Linac uses a for...

O. B. Oliveira Filho J. F. Ordonez S. Oliveira Junior



Metric System Resource Units = Unidades de Trabajo del Sistema Metrico Decimal. K-12. Project C.A.M.B.I.O., Changing Attitudes towards Metrics for Bilingual Instruction & Operations.  

ERIC Educational Resources Information Center

Four resource units are included in this document. For each, general objectives on knowledge and concepts, skills, and attitudes are given; content is outlined; and some suggestions for initiating the unit are listed. The first unit, on measuring length, provides six lesson plans, to teach about the meter, the smaller units of the meter, units…

Pulido, Josefina; Almendares, Simon


Sistema de Amostragem para Estimar a Area da Cultura do Trigo (Triticum Aestivum L) Atraves de Dados do LANDSAT (A Sampling System for Estimating the Cultivation of Wheat (Triticum Aestivum L) from LANDSAT Data).  

National Technical Information Service (NTIS)

Using digitally processed MSS/LANDSAT data as auxiliary variable, a methodology to estimate wheat (Triticum aestivum L) area by means of sampling techniques was developed. To perform this research, aerial photographs covering 720 sq km in Cruz Alta test s...

N. D. J. Parada M. A. Moreira



SWATCHP: Um Modelo para a Simulacao Continua de Processos Hidrologicos num Sistema Vegetacao-Solo-Aquifero-Rio (SWATCHP: A Model for the Continuous Simulation of the Hydrologic Processes in a Vegetation-Soil-Aquifer-Stream System).  

National Technical Information Service (NTIS)

A mathematical model (SWATCHP) for the continuous simulation of hydrologic processes is presented. The model is classified as a deterministic, physically based, distributed and a continuous one. The model simulates many of the hydrologic processes at the ...

P. G. M. de Melo Matias



COMPAR: sistema para comparar secoes de choque multigrupo geradas por NJOY, GROUPIE, FLANGE-II, ETOG-3 e XLACS. (COMPAR: system to compare multigroup cross sections generated by NJOY, GROUPIE, FLANGE-II, ETOG-3 AND XLACS).  

National Technical Information Service (NTIS)

A system, composed by the computer programs COMPAR and its interfaces, developed for comparing multigroup cross sections calculated by NJOY, GROUPIE, FLANGE-II, ETOG-3 and XLACS, is presented. (author). (Atomindex citation 22:069922)

J. Anaf E. S. Chalhoub



El desarrollo humano integral, la teoría de sistemas y el concepto de competencias en el ámbito académico universitario Integral human development and the concept of competitions in the university academic environment  

Microsoft Academic Search

RESUMEN: la Educación puede ser considerada como un proceso social, en el cual cada actividad y cada actor del proceso, deben tender hacia un desarrollo humano integral. En este sentido, el desarrollo humano podría ser visto como un promo - tor y conductor de mejora tanto personal como social. Hoy en día, sin embargo, la economía de libre mercado, es

Comunicación Técnica; Hilda L. Cárdenas


Moltiplicatore a Correzione d'Errore: Programmi Per la Scelta Delle Basi Del Sistema Numerico in Residui (Error Correcting Multiplier: Programs for the Choice of Bases of the Residual Numerical System).  

National Technical Information Service (NTIS)

The design of a multiplier implementing a logic and arithmetic unit is presented. The design is based on the combination of physical redundancy and residual arithmetic codes and the goal is to obtain a fault tolerant device. The residual arithmetic techni...

V. Piuri A. Fabi



Sistema de Tabulaci on de Coecientes Binomiales o Tri angulo de Pascal: un Modelo Num erico Rasga el Telar de los Tiempos Binomial Coecients' Tabulation System or Pascal's Triangle: a Numeric Model Rips the Loom of Time  

Microsoft Academic Search

One of the most famous numeric models of the History of Mathematics, Pascal's triangle, shows us its origin and shuttling throug the loom of time, since its oriental creation, almost magi- cal and forgotten, until becoming rooted in the occidental world.

Mara Cristina; Solaeche Galera


Diseno e implementacion del sistema de control de la nueva consola de control del Reactor Nuclear TRIGA Mark III del ININ. (Design and implementation of the control system for the new console of TRIGA-3-Salazar Reactor).  

National Technical Information Service (NTIS)

TRIGA-3-Salazar Reactor was set in operation in 1968 and the aging of its components has cause the increasing in the maintenance. In the presence of this, it becomes necessary to replace the reactor console using new technologies, considering the incorpor...

J. L. Gonzalez



Sistema de comunicaciones y analisis de espectros para detectores Ge-Li y GeHp. (Communication system and spectral analysis for Ge-Li and GeHp detectors).  

National Technical Information Service (NTIS)

An integral communication and spectral analysis system (SICADE) was developed and implemented to satisfy the need to optimize and automate the measurement system used in Atucha I nuclear power plant for the activity in the primary loop's water extracted b...

J. Fernandez P. Castano A. D. Bonino M. A. Righetti




Microsoft Academic Search

Uses of natural esters (vegetable oil) as insulating fluid have been reported, recently. This fluid has high biodegradability and high flash point what for safety reasons is attracting some attention in electrical industry. As insulating fluid is used for cooling, insulation and protection of the solid insulating paper, it is important to have some f knowledge about the paper ageing

Maria Augusta Martins; LABELEC-Grupo EDP



The origin of increased salinity in the Cambrian-Vendian aquifer system on the Kopli Peninsula, northern Estonia  

NASA Astrophysics Data System (ADS)

Monitoring of the confined Cambrian-Vendian aquifer system utilised for industrial water supply at Kopli Peninsula in Tallinn over 24 years reveals remarkable changes in chemical composition of groundwater. A relatively fast 1.5 to 3.0-fold increase in TDS and in concentrations of major ions in ed groundwater is the consequence of heavy pumping. The main sources of dissolved load in Cambrian-Vendian groundwater are the leaching of host rock and the other geochemical processes that occur in the saturated zone. Underlying crystalline basement, which comprises saline groundwater in its upper weathered and fissured portion, and which is hydraulically connected with the overlying Cambrian-Vendian aquifer system, is the second important source of ions. The fractured basement and its clayey weathering crust host the Ca-Cl type groundwater, which is characterised by high TDS values (2-20 g/L). Intensive water ion accelerates the exchange of groundwaters and increases the area of influence of pumping. Chemical and isotopic studies of groundwater indicate an increasing contribution of old brackish water from the crystalline basement and rule out the potential implication of an intrusion of seawater into aquifer. L'origine de la salinité croissante dans le système aquifère du Cambrien-Vendien dans la péninsule de Kopli, nord de l'Estonie Le suivi à long terme du système aquifère captif du Cambrien-Vendien utilisé pour l'approvisionnement d'eaux industrielles dans la Péninsule de Kopli, nord de l'Estonie, révèle de remarquables changements dans la composition chimique des eaux souterraines. Une augmentation de facteur 1.5 à 3 de la TDS et des concentrations en ions majeurs dans l'eau souterraine est la conséquence de pompages intensifs. Les sources principales des charges dissoutes dans les eaux de l'aquifère du Cambrien-Vendien sont le lessivage des roches et d'autres phénomènes géochimiques ayant lieu dans la zone saturée. Le soubassement rocheux cristallin, qui renferme des eaux souterraines salines dans sa partie supérieure altérée et fissurée, et est hydrauliquement connecté avec l'aquifère supérieur du Cambrien-Vendien, est la deuxième importante source d'ions. Le soubassement fracturé et le matériel argileux de l'altération, renferme l'eau souterraine de type Ca-Cl, caractérisée par un haut TDS (2-20 g/l). A cause de la mobilisation intensive de l'eau les échanges d'eau souterraine est sont accélérés et la zone d'influence des pompages augmentent. Les études chimiques et isotopiques indiquent une contribution croissante du drainage des eaux du soubassement cristallin. L'intrusion d'eaux salées de la mer dans le système aquifère n'est pas un phénomène évident. El origen del incremento en salinidad en un sistema de acuíferos Cámbrico-Vendiano en la Península Kopli, norte de Estonie Monitoreo a largo plazo de un sistema de acuíferos confinados, de edad Cámbrico-Vendiano, que se utiliza como fuente de abastecimiento industrial en la Península Kopli, al norte de Estonie, revela cambios notables en la composición química del agua subterránea. Un incremento de 1.5 a 3 veces en TDS y en concentraciones de iones mayores en agua subterránea explotada ha sido ocasionado por bombeo fuerte. Las fuentes principales de carga disuelta en el agua subterránea Cámbrico-Vendiano son la lixiviación de la roca encajonante y los procesos geoquímicos que ocurren en la zona saturada. Basamento cristalino subyacente, que aloja agua subterránea salada en la parte superior intemperizada y fisurada, y está conectado hidráulicamente con el sistema acuífero Cámbrico-Vendiano sobreyacente, es la segunda fuente importante de iones. El basamento fracturado y su corteza de intemperismo arcillosa alojan agua subterránea de tipo Ca-Cl la cual se caracteriza por valores altos de TDS (2-20 g/l). Debido a extracción intensiva se ha acelerado el intercambio de agua subterránea y se ha incrementado el área de influencia del bombeo. Los estudios químicos e isotópicos de agua subterránea indican una co

Karro, Enn; Marandi, Andres; Vaikmäe, Rein


Hydrochemical tracers in the middle Rio Grande Basin, USA: 1. Conceptualization of groundwater flow  

NASA Astrophysics Data System (ADS)

Chemical and isotopic data for groundwater from throughout the Middle Rio Grande Basin, central New Mexico, USA, were used to identify and map groundwater flow from 12 sources of water to the basin, evaluate radiocarbon ages, and refine the conceptual model of the Santa Fe Group aquifer system. Hydrochemical zones, representing groundwater flow over thousands to tens of thousands of years, can be traced over large distances through the primarily siliciclastic aquifer system. The locations of the hydrochemical zones mostly reflect the ``modern'' predevelopment hydraulic-head distribution, but are inconsistent with a trough in predevelopment water levels in the west-central part of the basin, indicating that this trough is a transient rather than a long-term feature of the aquifer system. Radiocarbon ages adjusted for geochemical reactions, mixing, and evapotranspiration/dilution processes in the aquifer system were nearly identical to the unadjusted radiocarbon ages, and ranged from modern to more than 30 ka. Age gradients from piezometer nests ranged from 0.1 to 2 year cm-1 and indicate a recharge rate of about 3 cm year-1 for recharge along the eastern mountain front and infiltration from the Rio Grande near Albuquerque. There has been appreciably less recharge along the eastern mountain front north and south of Albuquerque. Des données sur les éléments chimiques et les isotopes présents dans l'eau souterraine prélevée à divers endroits dans le bassin moyen du Rio Grande, au centre du Nouveau-Mexique (É-U), ont permis de déterminer l'existence et l'étendue de douze sources d'eau régionales dans le bassin, d'évaluer les âges radiocarbones et de raffiner le modèle conceptuel du système aquifère du groupe de Santa Fe. Des zones hydro-chimiques qui représentent l'écoulement de l'eau souterraine depuis des dizaines de milliers d'années peuvent être suivies sur de longues distances à travers l'aquifère principalement siliclastique. La position des zones hydro-chimiques reflète principalement la distribution moderne des charges hydrauliques mais est incohérente avec une dépression dans le niveau d'eau dans la partie centre-ouest du bassin, ce qui indique que cette dépression est un élément transitoire du système aquifère plutôt qu'un élément à long terme. Les âges radiocarbones ajustés aux réactions géochimiques et aux processus de mélange et d'évapotranspiration/dilution qui ont lieu dans l'aquifère sont presque identiques aux âges non ajustés et varient de la période moderne jusqu'à 30 ka. Les gradients d'âge établis à partir des nids de piézomètres s'étendent de 0.1 à 2 a cm-1 et suggèrent un taux de recharge d'environ 3 cm a-1 le long du front des montagnes à l'est et pour l'infiltration provenant du Rio Grande près d'Albuquerque. Il y a eu substantiellement moins de recharge le long du front des montagnes à l'est, au nord et au sud d'Albuquerque. Se utilizaron datos químicos e isotópicos de agua subterránea a lo largo de la cuenca central del río Grande, Nuevo México, EEUU, para identificar y mapear el flujo de agua subterránea de 12 fuentes de agua a la cuenca para evaluar edades por medio de radio carbon y para refinar el modelo conceptual del sistema acuífero del Grupo Santa Fé. Se puede establecer zonas hidrotérmicas que representan el flujo de agua subterránea a lo largo de miles a miles de decenas de años en grandes distancias a través del sistema acuífero principalmente siliclástico. Las ubicaciones de las zonas hidroquímicas mayormente reflejan la distribucion de la cabeza hidráulica pre-desarollo moderna pero son inconsistentes con una depresión en los niveles de agua pre-desarollo en la zona central oeste de la cuenca. Esto indica que esta depresión es un rasgo transitorio y no un rasgo de largo plazo del sistema acuífero. Las edades de radio carbon ajustadas para los procesos de reaciones geoquímicas, de mezclado y de evapotranspiración-dilución son casi idénticas a los edades de radio carbon no ajustadas oscilan en un rango desde la

Plummer, L. Niel; Bexfield, Laura M.; Anderholm, Scott K.; Sanford, Ward E.; Busenberg, Eurybiades


Atlas del Genoma del Cáncer

El Atlas del Genoma del Cáncer es una iniciativa de los Institutos Nacionales de la Salud (NIH) para crear mapas multidimensionales completos de los cambios genómicos clave en los tipos y subtipos principales de cáncer.


Évaluation des produits combinés  

Center for Biologics Evaluation and Research (CBER)

Text Version... des Centres respectifs. Les cases du tableau présentent quelques- unes des principales étapes d'examen. Veuillez noter ... More results from


Estados que requieren cobertura de los costos de estudios clínicos

Una lista de búsqueda y el mapa de los estados de EE.UU. requieren que los planes de salud para pagar los costos de la atención del paciente asociados con ensayos clínicos. Las principales disposiciones se resumen.


Quaternary dedolomitization along fracture systems in a late triassic Dolomitized platform (Western Southern Alps, Italy)  

Microsoft Academic Search

The studied area belongs to a south vergent thrust and fold belt of the Southern Alps of central Lombardy where the norian\\u000a Dolomia Principale crops out. This up to 2 km thick carbonate platform succession has been massively dolomitized from early\\u000a to shallow burial diagenesis.\\u000a \\u000a Dark grey, bedded dolostones (basal Dolomia Principale), outcropping along the both lower slopes of Iseo

P. Ronchi; F. Jadoul; R. Savino



Case-Based Multi-Sensor Intrusion Detection  

NASA Astrophysics Data System (ADS)

Multi-sensor intrusion detection systems (IDSs) combine the alerts raised by individual IDSs and possibly other kinds of devices such as firewalls and antivirus software. A critical issue in building a multi-sensor IDS is alert-correlation, i.e., determining which alerts are caused by the same attack. This paper explores a novel approach to alert correlation using case-based reasoning (CBR). Each case in the CBR system's library contains a pattern of alerts raised by some known attack type, together with the identity of the attack. Then during run time, the alert streams gleaned from the sensors are compared with the patterns in the cases, and a match indicates that the attack described by that case has occurred. For this purpose the design of a fast and accurate matching algorithm is imperative. Two such algorithms were explored: (i) the well-known Hungarian algorithm, and (ii) an order-preserving matching of our own device. Tests were conducted using the DARPA Grand Challenge Problem attack simulator. These showed that the both matching algorithms are effective in detecting attacks; but the Hungarian algorithm is inefficient; whereas the order-preserving one is very efficient, in fact runs in linear time.

Schwartz, Daniel G.; Long, Jidong



Phenylpropanoids as naturally occurring antioxidants: from plant defense to human health.  


Phenylpropanoids (PPs) belong to the largest group of secondary metabolites produced by plants, mainly, in response to biotic or abiotic stresses such as infections, wounding, UV irradiation, exposure to ozone, pollutants, and other hostile environmental conditions. It is thought that the molecular basis for the protective action of phenylpropanoids in plants is their antioxidant and free radical scavenging properties. These numerous phenolic compounds are major biologically active components of human diet, spices, aromas, wines, beer, essential oils, propolis, and traditional medicine. Last few years, much interest has been attracted to natural and synthetic phenylpropanoids for medicinal use as antioxidant, UV screens, anticancer, anti-virus, anti-inflammatory, wound healing, and antibacterial agents. They are of great interest for cosmetic and perfume industries as active natural ingredients. In the present review, the metabolic pathways of phenylpropanoid biosynthesis in plants and the mechanism of phenylpropanoid-mediated plant defense are described. Learning from plants, free radical-driven, molecular and cellular processes modulated by phenylpropanoids in human cell cultures in vitro and in the in vivo animal models of tumors, inflammation, and cellular damage are also reviewed. PMID:17519109

Korkina, L G



Character of HBV (hepatitis B virus) polymerase gene rtM204V/I and rtL180M mutation in patients with lamivudine resistance  

PubMed Central

Objectives: To investigate the relationship between HBV (hepatitis B virus) polymerase gene 180 and 204 sites mutation and lamivudine resistance. Methods: One hundred forty-one patients with lamivudine resistance after lamivudine treatment and 60 chronic hepatitis B patients without lamivudine treatment were enrolled in this study. The serum HBV DNA mutation was analyzed by sequence detection via polymerase chain reaction (PCR). The sequences of the same patient were analyzed before and after lamivudine treatment. Results: One hundred and nine lamivudine resistance patients had HBV YMDD (tyrosine-methionine-aspartate-aspartate) mutation. Among them, 45 patients had rtL180M/M204V mutation (41.28%), 28 patients had rtL180M/M204I mutation (25.70%) and 36 patients had rtM204I mutation (33.02%). There were 6 patients with rtL180M mutation in 32 lamivudine resistance patients. Sixty chronic hepatitis patients without lamivudine treatment had no mutations. Conclusions: HBV mutations, which play an important role in lamivudine resistance usually locate at polymerase gene 204 site; 180 site mutation was also observed in these patients. Evaluation of the anti-virus therapy by surveillance of the two sites mutations is of importance.

Li, Min-wei; Hou, Wei; Wo, Jian-er; Liu, Ke-zhou



Proteochemometric Modeling of the Bioactivity Spectra of HIV-1 Protease Inhibitors by Introducing Protein-Ligand Interaction Fingerprint  

PubMed Central

HIV-1 protease is one of the main therapeutic targets in HIV. However, a major problem in treatment of HIV is the rapid emergence of drug-resistant strains. It should be particularly helpful to clinical therapy of AIDS if one method can be used to predict antivirus capability of compounds for different variants. In our study, proteochemometric (PCM) models were created to study the bioactivity spectra of 92 chemical compounds with 47 unique HIV-1 protease variants. In contrast to other PCM models, which used Multiplication of Ligands and Proteins Descriptors (MLPD) as cross-term, one new cross-term, i.e. Protein-Ligand Interaction Fingerprint (PLIF) was introduced in our modeling. With different combinations of ligand descriptors, protein descriptors and cross-terms, nine PCM models were obtained, and six of them achieved good predictive abilities (Q2test>0.7). These results showed that the performance of PCM models could be improved when ligand and protein descriptors were complemented by the newly introduced cross-term PLIF. Compared with the conventional cross-term MLPD, the newly introduced PLIF had a better predictive ability. Furthermore, our best model (GD & P & PLIF: Q2test?=?0.8271) could select out those inhibitors which have a broad antiviral activity. As a conclusion, our study indicates that proteochemometric modeling with PLIF as cross-term is a potential useful way to solve the HIV-1 drug-resistant problem.

Liu, Qi; Wu, Qiong; Kang, Hong; Cao, Zhiwei; Zhu, Ruixin



Inhibition of B16 melanoma experimental metastasis by interferon-? through direct inhibition of cell proliferation and activation of antitumour host mechanisms  

PubMed Central

Interferon-? (IFN-?) has pleiotropic activities other than its antivirus action, including cell growth inhibition, natural killer (NK) cell and cytotoxic T lymphocyte (CTL) activation, and angiogenesis inhibitory activity, and these activities are supposed to be involved in its antitumour activity. However, it has not been completely elucidated which activity is mainly involved in the tumour suppression in vivo. In this study, we analysed inhibitory mechanisms of endogenous IFN-? against B16 melanoma experimental metastasis. After intravenous injection of tumour cells, tumour deposits in the lungs and liver were increased and life span was shorter in IFN-??/? mice, indicating important roles for IFN-? in antitumour mechanisms. Interestingly, tumour deposits were not increased in IFN-? receptor (R)?/? mice. Furthermore, only low levels of cell-mediated immunity against the tumour and activation of NK cells were observed, indicating that antimetastatic effects of IFN-? is not mediated by host cells. The survival period of B16 melanoma-bearing IFN-?R?/? mice was, however, shorter than wild-type mice. These observations suggest that IFN-? prevents B16 melanoma experimental metastasis by directly inhibiting the cell growth, although antitumour host functions may also be involved in a later phase.

Kakuta, Shigeru; Tagawa, Yoh-ichi; Shibata, Shinwa; Nanno, Masanobu; Iwakura, Yoichiro



Studies on Chromatographic Fingerprint and Fingerprinting Profile-Efficacy Relationship of Polygoni Perfoliati Herba  

PubMed Central

Polygoni Perfoliati Herba is widely used in China with antibacterium, anti-inflammatory, expectorant, antitumor, and antivirus activities. To reveal the mechanisms of the activities of Polygoni Perfoliati Herba, the relationship between the fingerprinting profile and its bioactivities was investigated. In the present study, high-performance liquid chromatographic (HPLC) fingerprinting method was developed. The established method was applied to analyze 51 batches of Polygoni Perfoliati Herba samples collected from different locations or in different harvesting times in China. Chemometrics, including similarity analysis, hierarchical clustering analysis, and principal component analysis, were used to express their similarities. It was found that similarity values of the samples were in the range of 0.432–0.998. The results of analgesic tests indicated that Polygoni Perfoliati Herba could significantly inhibit pain induced by hot plate and acetic acid in mice. The results of anti-inflammatory tests showed that Polygoni Perfoliati Herba had good anti-inflammatory effects (P < 0.01) in two models including dimethyl benzene-induced ear edema and acetic acid-induced peritoneal permeability in mice. Combining the results from chromatographic fingerprints with those from bioactivities, we found that seven peaks from Polygoni Perfoliati Herba were mainly responsible for analgesic and anti-inflammatory activities.

Tian, Li; Chen, Hua-Guo; Zhao, Chao; Gong, Xiao-Jian



Studies on acyclovir-dextran conjugate: synthesis and pharmacokinetics.  


Acyclovir is an antivirus drug which has a good in vitro activity against hepatitis B virus. But because of the low solubility and low distribution in liver, the clinical application of acyclovir in hepatitis B was limited. To increase the solubility and the distribution in liver, acyclovir-dextran conjugate was synthesized by formation of Schiff's base. The solubility of obtained conjugate was 12 times greater than free acyclovir. Acyclovir will be slowly released from the obtained conjugate in pH 7.4 phosphate buffer solution (PBS) at 37 degrees C with a rate constant of 0.0035 hr(-1). Pharmacokinetic studies of acyclovir and acyclovir-dextran conjugate were conducted in mice by i.v. administration. Acyclovir concentrations in plasma, liver and kidney were determined by HPLC method. Relatively higher distribution of acyclovir in liver was observed when i.v. acyclovir-dextran conjugate as compared with i.v. free acyclovir. The results of pharmacokinetic studies indicated that acyclovir-dextran conjugate will be a good candidate to treat hepatitis B. PMID:15554220

Tu, Jiasheng; Zhong, Sha; Li, Pengmei



Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives -- a screening based on affinity for the UMP-CMP binding site.  


Methylanthraniloyl derivatives of ATP and CDP were used in vitro as fluorescent probes for the donor-binding and acceptor-binding sites of human UMP-CMP kinase, a nucleoside salvage pathway kinase. Like all NMP kinases, UMP-CMP kinase binds the phosphodonor, usually ATP, and the NMP at different binding sites. The reaction results from an in-line phosphotransfer from the donor to the acceptor. The probe for the donor site was displaced by the bisubstrate analogs of the Ap5X series (where X = U, dT, A, G), indicating the broad specificity of the acceptor site. Both CMP and dCMP were competitors for the acceptor site probe. To find antimetabolites for antivirus and anticancer therapies, we have developed a method of screening acyclic phosphonate analogs that is based on the affinity of the acceptor-binding site of the human UMP-CMP kinase. Several uracil vinylphosphonate derivatives had affinities for human UMP-CMP kinase similar to those of dUMP and dCMP and better than that of cidofovir, an acyclic nucleoside phosphonate with a broad spectrum of antiviral activities. The uracil derivatives were inhibitors rather than substrates of human UMP-CMP kinase. Also, the 5-halogen-substituted analogs inhibited the human TMP kinase less efficiently. The broad specificity of the enzyme acceptor-binding site is in agreement with a large substrate-binding pocket, as shown by the 2.1 A crystal structure. PMID:17608725

Topalis, Dimitri; Kumamoto, Hiroki; Amaya Velasco, Maria-Fernanda; Dugué, Laurence; Haouz, Ahmed; Alexandre, Julie Anne C; Gallois-Montbrun, Sarah; Alzari, Pedro Maria; Pochet, Sylvie; Agrofoglio, Luigi André; Deville-Bonne, Dominique



Studies on chromatographic fingerprint and fingerprinting profile-efficacy relationship of polygoni perfoliati herba.  


Polygoni Perfoliati Herba is widely used in China with antibacterium, anti-inflammatory, expectorant, antitumor, and antivirus activities. To reveal the mechanisms of the activities of Polygoni Perfoliati Herba, the relationship between the fingerprinting profile and its bioactivities was investigated. In the present study, high-performance liquid chromatographic (HPLC) fingerprinting method was developed. The established method was applied to analyze 51 batches of Polygoni Perfoliati Herba samples collected from different locations or in different harvesting times in China. Chemometrics, including similarity analysis, hierarchical clustering analysis, and principal component analysis, were used to express their similarities. It was found that similarity values of the samples were in the range of 0.432-0.998. The results of analgesic tests indicated that Polygoni Perfoliati Herba could significantly inhibit pain induced by hot plate and acetic acid in mice. The results of anti-inflammatory tests showed that Polygoni Perfoliati Herba had good anti-inflammatory effects (P < 0.01) in two models including dimethyl benzene-induced ear edema and acetic acid-induced peritoneal permeability in mice. Combining the results from chromatographic fingerprints with those from bioactivities, we found that seven peaks from Polygoni Perfoliati Herba were mainly responsible for analgesic and anti-inflammatory activities. PMID:24023580

Tian, Li; Zhao, Yang; Zhou, Xin; Chen, Hua-Guo; Zhao, Chao; Gong, Xiao-Jian



In vitro anti-influenza A H1N1 effect of extract of Bupleuri Radix.  


This study investigated the effect of the extract of Bupleuri Radix (BRE) on the infection of Madin-Darby Canine Kidney (MDCK) cells by anti-H1N1 virus. The effect of BRE on RANTES (the chemokine regulated on activation, normal T cells expressed and secreted) secretion in H1N1-infected A549 cells (human bronchial epithelial cells) was evaluated via quantative measurement of the changes in the cytopathic effects and by the ultraviolet (UV) absorbance at 600?nm. It was found that BRE was toxic to MDCK cells at a higher concentration while had a marked inhibitory effect on cell pathological changes at a lower concentration. Results also showed that BRE possessed more than 50% suppressing effect on RANTES secretion in H1N1-infected A549 cells at a concentration of 100 and 200 ?g/ml. Our findings show that BRE has a significant protective effect on MDCK cells infected in a dose-dependent manner with an excellent suppressing effect on RANTES secretion, suggesting that BRE can be developed as an antivirus agent. PMID:21039315

Wen, Su; Huifu, Xu; Hao, Huang



Diketopiperazine Derivatives from the Marine-Derived Actinomycete Streptomyces sp. FXJ7.328  

PubMed Central

Five new diketopiperazine derivatives, (3Z,6E)-1-N-methyl-3-benzylidene-6-(2S-methyl-3-hydroxypropylidene)piperazine-2,5-dione (1), (3Z,6E)-1-N-methyl-3-benzylidene-6-(2R-methyl-3-hydroxypropylidene)piperazine-2,5-dione (2), (3Z,6Z)-3-(4-hydroxybenzylidene)-6-isobutylidenepiperazine-2,5-dione (3), (3Z,6Z)-3-((1H-imidazol-5-yl)-methylene)-6-isobutylidenepiperazine-2,5-dione (4), and (3Z,6S)-3-benzylidene-6-(2S-but-2-yl)piperazine-2,5-dione (5), were isolated from the marine-derived actinomycete Streptomyces sp. FXJ7.328. The structures of 1–5 were determined by spectroscopic analysis, CD exciton chirality, the modified Mosher’s, Marfey’s and the C3 Marfey’s methods. Compound 3 showed modest antivirus activity against influenza A (H1N1) virus with an IC50 value of 41.5 ± 4.5 ?M. In addition, compound 6 and 7 displayed potent anti-H1N1 activity with IC50 value of 28.9 ± 2.2 and 6.8 ± 1.5 ?M, respectively. Due to the lack of corresponding data in the literature, the 13C NMR data of (3Z,6S)-3-benzylidene-6-isobutylpiperazine-2,5-dione (6) were also reported here for the first time.

Wang, Pei; Xi, Lijun; Liu, Peipei; Wang, Yi; Wang, Wei; Huang, Ying; Zhu, Weiming



Differential effect in vitro of tumor necrosis factor-alpha (TNF) on normal and virus-infected erythroid progenitors from Friend virus (FVA)-infected mice.  


In vivo administration of tumor necrosis factor-alpha (TNF) suppresses both normal and Friend virus (FVA)-infected erythroid progenitor cells (CFU-E). To examine the mechanism of erythroid suppression by TNF, we examined TNF's direct effect on normal and virus-infected cells in vitro. Productively infected fibroblast cell lines, fresh acute virus-infected spleen cells, and virus-infected CFU-E were sensitive, whereas uninfected CFU-E were resistant to TNF cytotoxicity in vitro. When FVA-infected erythroblasts were depleted from the spleen cell population in vitro with antivirus antibodies, TNF suppression of the remaining (uninfected) cells was abrogated. In contrast, both normal and virus-infected macrophage progenitor cells and immature erythroid progenitor cells were equally sensitive to TNF cytotoxicity in vitro. Normal erythroblasts had significantly fewer TNF receptors than FVA-infected erythroblasts, which also were morphologically less mature. These results suggest that TNF can differentially suppress late-stage virus-infected erythroid progenitors in vitro. PMID:1337323

Chang, M J; Pourbohloul, S C; Yu, W D; Furmanski, P; Johnson, C S



Tailoring the pH Dependence of Human Non-pancreatic Secretory Phospholipase A2 by Engineering Surface Charges.  


Human non-pancreatic secretory phospholipase A2 (hnpsPLA2) catalyzes the sn-2 acyl hydrolysis of phospholipids. It was reported that hnpsPLA2 is involved in various diseases like inflammation, cancer, and so on. This enzyme also exhibits anti-bacterial and anti-virus activities. It is active over a broad pH range, with higher activity at alkaline conditions. In order to make it suitable as a potential bactericide, high activity at neutral pH is preferable. We have tried to tailor the pH dependence of hnpsPLA2 activity by replacing its surface charged residues. Three surface charge replacements, Arg42Glu, Arg100Glu, and Glu89Lys, showed increased activities at neutral pH, which are 2.3, 2.8, and 2.3 times that of the wild-type enzyme at pH 7. Both the positive-to-negative and negative-to-positive mutations lowered the optimum enzymatic reaction pH of hnpsPLA2, indicating that the enzyme pH profile depends on a delicate balance of charged residues. The activity changes are in good agreement with the recently proposed calcium-coordinated catalytic triad mechanism. This study also provides a general means of enhancing hnpsPLA2 activity at low pH. PMID:23955349

Qiu, Shunchen; Lai, Luhua



Cell-based analysis of Chikungunya virus membrane fusion using baculovirus-expression vectors.  


Chikungunya virus infection has emerged in many countries over the past decade. There are no effective drugs for controlling the disease. To develop cell-based system for screening anti-virus drugs, a bi-cistronic baculovirus expression system was utilized to co-express viral structural proteins C (capsid), E2 and E1 and the enhanced green fluorescence protein (EGFP) in Spodoptera frugiperda insect cells (Sf21). The EGFP-positive Sf21 cells fused with each other and with uninfected cells to form a syncytium, allowing characterization of cholesterol and low pH requirements for syncytium formation. Western blot analysis showed three structural proteins were expressed in baculovirus infected cells. The structural proteins of Chikungunya virus that is required for cell fusion was determined with various recombinant baculoviruses bearing different lengths of the viral structural protein genes. Protein E1 was required for cell fusion and indicating that Chikungunya viral membrane fusion was a class II membrane fusion. It was also demonstrated that the heterologous expression of alphavirus monomeric E1 can induce insect cell fusions. Furthermore, this cell-based system provides a model for studying class II viral membrane fusion. PMID:21619896

Kuo, Szu-Cheng; Chen, Ying-Ju; Wang, Yu-Ming; Kuo, Ming-Der; Jinn, Tzyy-Rong; Chen, Wen-Shuo; Chang, Yen-Chung; Tung, Kuo-Lun; Wu, Tzong-Yuan; Lo, Szecheng J



Computational identification of a new binding site in influenza virus hemagglutinin for membrane fusion inhibitors.  


The influenza virus hemagglutinin is a potential drug target for antivirus treatment. A variety of membrane fusion inhibitors targeting hemagglutinin have been discovered, but the binding sites and modes, important for understanding membrane fusion and rational drug design, have not yet been elucidated. In this article, we investigated the possible hemagglutinin binding sites for the current membrane fusion inhibitors. Four possible binding pockets (Pocket A, B, C, and D) at the stalk region of hemagglutinin were detected and defined using the CAVITY program. Most of the current membrane fusion inhibitors were reported to bind to Pocket C by amino acid mutation experiments and molecular modeling simulation. However, our binding site prediction suggested that Pocket A is the best ligand binding site other than Pocket C. Using a specific computational protocol combining molecular docking, three-dimensional QSAR, and receptor mimicking, we further found that Pocket A is the putative binding site for a series of membrane fusion inhibitors (1-phenyl-cycloalkane carbamides). This is further proven by the antiviral spectrum of the inhibitors. This protocol for the identification of ligand binding sites in influenza hemagglutinin is also applicable for the analysis of other protein targets with no explicit binding information. PMID:23647909

Sun, Lidan; Tian, Feng; Feng, Baosheng; Liu, Zhenming; Zhang, Liangren; Pei, Jianfeng



Practical application of bioinformatics by the multidisciplinary VIZIER consortium.  


This review focuses on bioinformatics technologies employed by the EU-sponsored multidisciplinary VIZIER consortium (Comparative Structural Genomics of Viral Enzymes Involved in Replication, FP6 Project: 2004-511960, active from 1 November 2004 to 30 April 2009), to achieve its goals. From the management of the information flow of the project, to bioinformatics-mediated selection of RNA viruses and prediction of protein targets, to the analysis of 3D protein structures and antiviral compounds, these technologies provided a communication framework and integrated solutions for steady and timely advancement of the project. RNA viruses form a large class of major pathogens that affect humans and domestic animals. Such RNA viruses as HIV, Influenza virus and Hepatitis C virus are of prime medical concern today, but the identities of viruses that will threaten human population tomorrow are far from certain. To contain outbreaks of common or newly emerging infections, prototype drugs against viruses representing the Virus Universe must be developed. This concept was championed by the VIZIER project which brought together experts in diverse fields to produce a concerted and sustained effort for identifying and validating targets for antivirus therapy in dozens of RNA virus lineages. PMID:20153379

Gorbalenya, Alexander E; Lieutaud, Philippe; Harris, Mark R; Coutard, Bruno; Canard, Bruno; Kleywegt, Gerard J; Kravchenko, Alexander A; Samborskiy, Dmitry V; Sidorov, Igor A; Leontovich, Andrey M; Jones, T Alwyn



DROP: Detecting Return-Oriented Programming Malicious Code  

NASA Astrophysics Data System (ADS)

Return-Oriented Programming (ROP) is a new technique that helps the attacker construct malicious code mounted on x86/SPARC executables without any function call at all. Such technique makes the ROP malicious code contain no instruction, which is different from existing attacks. Moreover, it hides the malicious code in benign code. Thus, it circumvents the approaches that prevent control flow diversion outside legitimate regions (such as W ? X ) and most malicious code scanning techniques (such as anti-virus scanners). However, ROP has its own intrinsic feature which is different from normal program design: (1) uses short instruction sequence ending in "ret", which is called gadget, and (2) executes the gadgets contiguously in specific memory space, such as standard GNU libc. Based on the features of the ROP malicious code, in this paper, we present a tool DROP, which is focused on dynamically detecting ROP malicious code. Preliminary experimental results show that DROP can efficiently detect ROP malicious code, and have no false positives and negatives.

Chen, Ping; Xiao, Hai; Shen, Xiaobin; Yin, Xinchun; Mao, Bing; Xie, Li


Rig-I regulates NF-?B activity through binding to Nf-?b1 3?-UTR mRNA  

PubMed Central

Retinoic acid inducible gene I (RIG-I) senses viral RNAs and triggers innate antiviral responses through induction of type I IFNs and inflammatory cytokines. However, whether RIG-I interacts with host cellular RNA remains undetermined. Here we report that Rig-I interacts with multiple cellular mRNAs, especially Nf-?b1. Rig-I is required for NF-?B activity via regulating Nf-?b1 expression at posttranscriptional levels. It interacts with the multiple binding sites within 3?-UTR of Nf-?b1 mRNA. Further analyses reveal that three distinct tandem motifs enriched in the 3?-UTR fragments can be recognized by Rig-I. The 3?-UTR binding with Rig-I plays a critical role in normal translation of Nf-?b1 by recruiting the ribosomal proteins [ribosomal protein L13 (Rpl13) and Rpl8] and rRNAs (18S and 28S). Down-regulation of Rig-I or Rpl13 significantly reduces Nf-?b1 and 3?-UTR–mediated luciferase expression levels. These findings indicate that Rig-I functions as a positive regulator for NF-?B signaling and is involved in multiple biological processes in addition to host antivirus immunity.

Zhang, Hong-Xin; Liu, Zi-Xing; Sun, Yue-Ping; Lu, Shun-Yuan; Liu, Xue-Song; Huang, Qiu-Hua; Xie, Yin-Yin; Dang, Su-Ying; Zheng, Guang-Yong; Li, Yi-Xue; Kuang, Ying; Fei, Jian; Chen, Zhu; Wang, Zhu-Gang



Rig-I regulates NF-?B activity through binding to Nf-?b1 3'-UTR mRNA.  


Retinoic acid inducible gene I (RIG-I) senses viral RNAs and triggers innate antiviral responses through induction of type I IFNs and inflammatory cytokines. However, whether RIG-I interacts with host cellular RNA remains undetermined. Here we report that Rig-I interacts with multiple cellular mRNAs, especially Nf-?b1. Rig-I is required for NF-?B activity via regulating Nf-?b1 expression at posttranscriptional levels. It interacts with the multiple binding sites within 3'-UTR of Nf-?b1 mRNA. Further analyses reveal that three distinct tandem motifs enriched in the 3'-UTR fragments can be recognized by Rig-I. The 3'-UTR binding with Rig-I plays a critical role in normal translation of Nf-?b1 by recruiting the ribosomal proteins [ribosomal protein L13 (Rpl13) and Rpl8] and rRNAs (18S and 28S). Down-regulation of Rig-I or Rpl13 significantly reduces Nf-?b1 and 3'-UTR-mediated luciferase expression levels. These findings indicate that Rig-I functions as a positive regulator for NF-?B signaling and is involved in multiple biological processes in addition to host antivirus immunity. PMID:23553835

Zhang, Hong-Xin; Liu, Zi-Xing; Sun, Yue-Ping; Zhu, Jiang; Lu, Shun-Yuan; Liu, Xue-Song; Huang, Qiu-Hua; Xie, Yin-Yin; Zhu, Hou-Bao; Dang, Su-Ying; Chen, Hai-Feng; Zheng, Guang-Yong; Li, Yi-Xue; Kuang, Ying; Fei, Jian; Chen, Sai-Juan; Chen, Zhu; Wang, Zhu-Gang



Subversion and piracy: DNA viruses and immune evasion.  


During the co-evolution of viruses with their vertebrate hosts, the DNA viruses have acquired an impressive array of immunomodulatory genes to combat host immune responses and their hosts have developed a sophisticated immune system to contain virus infections. In order to replicate, the viruses have evolved mechanisms to inhibit key host anti-virus responses that include apoptosis, interferon production, chemokine production, inflammatory cytokine production, and the activity of cytotoxic T-cells, natural killer cells and antibody. In addition, some of the viruses encode cytokine or chemokine homologues that recruit or expand cell numbers for infection or that subvert the host cellular response from a protective response to a benign one. The specificity of the viral immunomodulatory molecules reflects the life cycle and the pathogenesis of the viruses. Herpesviruses achieve latency in host cells by inducing cell survival and protecting infected cells from immune recognition. This involves interference with cell signal transduction pathways. Many of the viral immunomodulatory proteins are homologues of host proteins that appear to have been pirated from the host and reassorted in the virus genomes. Some of these have unique functions and indicate novel or important aspects of both viral pathogenesis and host immunity to viruses. The specific example of orf virus infection of sheep is described. PMID:11676616

Haig, D M



Encephalitis due to emerging viruses: CNS innate immunity and potential therapeutic targets.  


The emerging viruses represent a group of pathogens that are intimately connected to a diverse range of animal vectors. The recent escalation of air travel climate change and urbanization has meant humans will have increased risk of contacting these pathogens resulting in serious CNS infections. Many RNA viruses enter the CNS by evading the BBB due to axonal transport from the periphery. The systemic adaptive and CNS innate immune systems express pattern recognition receptors PRR (TLRs, RiG-1 and MDA-5) that detect viral nucleic acids and initiate host antiviral response. However, several emerging viruses (West Nile Fever, Influenza A, Enterovirus 71 Ebola) are recognized and internalized by host cell receptors (TLR, MMR, DC-SIGN, CD162 and Scavenger receptor B) and escape immuno surveillance by the host systemic and innate immune systems. Many RNA viruses express viral proteins WNF (E protein), Influenza A (NS1), EV71 (protein 3C), Rabies (Glycoprotein), Ebola proteins (VP24 and VP 35) that inhibit the host cell anti-virus Interferon type I response promoting virus replication and encephalitis. The therapeutic use of RNA interference methodologies to silence gene expression of viral peptides and treat emerging virus infection of the CNS is discussed. PMID:22484271

Denizot, M; Neal, J W; Gasque, P



Molecular cloning, recombinant expression, and antimicrobial activity of EC-hepcidin3, a new four-cysteine hepcidin isoform from Epinephelus coioides.  


Hepcidin, a cysteine-rich antimicrobial peptide, is widespread in fish and shows multiple activities, including antimicrobial, antivirus, and antitumor. Here, a new four-cysteine hepcidin isoform gene, EC-hepcidin3, was cloned from the marine-cultured orange-spotted grouper (Epinephelus coioides). The complete cDNA sequence consisted of 603 bases with an open reading frame (ORF) of 270 bases. The genomic DNA sequence was composed of two introns and three exons, and its 312-bp upstream region had multiple putative transcription factor binding sites. Soluble recombinant protein EC-proHep3 containing a His-tag at the C-terminus was obtained from expression plasmid pET-28a/EC-proHep3 in Escherichia coli Rosetta. It was purified by immobilized metal affinity chromatography (IMAC), and it showed antibacterial activity in vitro. Kinetic studies indicated that recombinant EC-proHep3 has strong, rapid activity against Staphylococcus aureus and Pseudomonas stutzeri. The results indicate that EC-hepcidin3 might be an effective component in the innate immune system of groupers. PMID:23291752

Qu, HaiDong; Chen, Bei; Peng, Hui; Wang, KeJian



Investigation of Effects and Mechanisms of Total Flavonoids of Astragalus and Calycosin on Human Erythroleukemia Cells  

PubMed Central

Flavonoids are found in most parts of plants and have been shown to have multiple biological activities such as anticancer, anti-inflammation, antibacteria, antivirus, and immune-stimulation. Existing data showed that the total flavonoids of Astragalus (TFA) can provide biological system with resistance to injury and can possess antimutagenic, atherosclerotic inhibition, and other biological effects. This study investigated the effects of TFA and calycosin (a compound isolated from TFA), on apoptosis induction, and cell cycle of human erythroleukemia cell line K562 by an array of techniques, including proliferation (MTT), PI staining, Annexin V/PI double staining, and RT-PCR. The experimental data showed that TFA and calycosin could inhibit the proliferation of K562 cells. The 50% inhibiting concentrations of TFA and calycosin were 98.63??g/mL and 130.32??g/mL, respectively. However, TFA and calycosin could not induce apoptosis in K562 cells, but could increase the number of the cells in the G0/G1 phase. The level of cyclin D1 mRNA in K562 cells decreased after the treatment with TFA and calycosin. This study provides new insights into the functional mechanism of total flavonoids of Astragalus and calycosin on human erythroleukemia cells.

Zhang, Dongqing; Zhuang, Yuan; Pan, Jichun; Wang, Haibao; Li, Hui; Yu, Yang; Wang, Deqing



A versatile multicomponent assembly via ?-cyclodextrin host-guest chemistry on graphene for biomedical applications.  


A multi-component nanosystem based on graphene and comprising individual cyclodextrins at its surface is assembled, creating hybrid structures enabling new and important functionalities: optical imaging, drug storage, and cell targeting for medical diagnosis and treatment. These nanohybrids are part of a universal system of interchangeable units, capable of mutilple functionalities. The surface components, made of individual ?-cyclodextrin molecules, are the "hosts" for functional units, which may be used as imaging agents, for anti-cancer drug delivery, and as tumor-specific ligands. Specifically, individual ?-cyclodextrin (?-CD), with a known capability to host various molecules, is considered a module unit that is assembled onto graphene nanosheet (GNS). The cyclodextrin-functionalized graphene nanosheet (GNS/?-CD) enables "host-guest" chemistry between the nanohybrid and functional "payloads". The structure, composition, and morphology of the graphene nanosheet hybrid have been investigated. The nanohybrid, GNS/?-CD, is highly dispersive in various physiological solutions, reflecting the high biostability of cyclodextrin. Regarding the host capability, the nanohybrid is fully capable of selectively accommodating various biological and functional agents in a controlled fashion, including the antivirus drug amantadine, fluorescent dye [5(6)-carboxyfluorescein], and Arg-Gly-Asp (RGD) peptide-targeting ligands assisted by an adamantine linker. The loading ratio of 5(6)-carboxyfluorescein is as high as 110% with a drug concentration of 0.45 mg mL(-1). The cyclic RGD-functionalized nanohybrid exhibits remarkable targeting for HeLa cells. PMID:23047287

Dong, Haiqing; Li, Yongyong; Yu, Jinhai; Song, Yanyan; Cai, Xiaojun; Liu, Jiaqiang; Zhang, Jiaming; Ewing, Rodney C; Shi, Donglu



Biréfringence électrique et polarisabilités moléculaires de CF2Cl-CCl3  

NASA Astrophysics Data System (ADS)

Nous nous proposons de déterminer les valeurs des polarisabilités moléculaires relatives aux trois radiations principales de l'arc au mercure, ainsi que la direction des axes de l'ellipsoïde de polarisabilité optique de CF2Cl-CCl3, à partir des résultats de mesures d'effet Kerr de ce composé à l'état liquide. La biréfringence électrique de CF2Cl-CCl3 change de signe à la température T0=295 K. Ainsi nous obtenons une relation supplémentaire très utile entre les valeurs principales du tenseur de polarisabilité. Nous utilisons pour l'expression de la constante de Kerr la formule de Langevin-Born et faisons appel à la théorie des polarisabilités de liaisons pour calculer la valeur de la polarisabilité principale normale au plan de symétrie de CF2Cl-CCl3.

Benoit-Denis, Anne-Marie


Tratamiento de la infección de esternotomía media con terapia de vacío  

Microsoft Academic Search

Objetivo: Conocer la aplicabilidad y eficacia de este tratamiento usando un sistema artesanal que nos permite aplicar este concepto terapéutico sin disponer del dispositivo actualmente comercializado (KCI

López Almodóvar; Luis Fernando; Cañas Alfonso; Lima Pedro; Calleja Manuel


In vitro evaluation of the effects of the interaction between irrigating solutions, intracanal medication and Er:YAG laser in dentin permeability of the endodontic system Estudo in vitro dos efeitos da interação de substâncias irrigantes, medicação intracanal e laser Er:YAG na permeabilidade dentinária do sistema endodôntico  

Microsoft Academic Search

The purpose of this study was to evaluate in vitro the effects of different associations between irrigating so- lutions (EDTA-T and citric acid), intracanal medicament (NDP), and Er:YAG laser irradiation on dentin permeability. Fifty-one extracted single-rooted teeth were instrumented and divided into seven groups. Groups GI and GII had final irrigation with a demineralizing solution only (EDTA-T and citric acid,

Denise Pontes Raldi; José Luiz Lage-Marques


NIVELES DE INMUNOGLOBULINAS (IgM, IgG e IgA) EN SUERO SANGUÍNEO DE BÚFALOS DE AGUA, BAJO DOS SISTEMAS DE AMAMANTAMIENTO DIFERENTES Blood serum Inmunoglobulins levels (IgM, IgG, IgA) in Water Buffaloes under two Different Weaning Systems  

Microsoft Academic Search

Water buffaloes production has increased greatly during the late 90's having the nead of better production systems in this kind of exploitations. There has been a tendency to determine the biological and physiological parameters as well as the nu- tritional condition of these animals. Blood serum Inmunoglobu- lins (IgM, IgG and IgA) levels were measured in 30 samples from two

Oswaldo E. Vale Echeto; José D. Vargas; María A. Vale Oviedo; María G. Oviedo de Vale


Efecto de la pesca artesanal de camarón sobre la ictiofauna en el sistema lagunar de Santa María la Reforma, suroeste del Golfo de California Effect of the artisanal shrimp fishery on the ichthyofauna in the coastal lagoon of Santa María la Reforma, southeastern Gulf of California  

Microsoft Academic Search

The effect of the artisanal shrimp fishery on the fish fauna in the coastal lagoon of Santa María la Reforma, Mexico, was assessed. Twenty-nine stations were sampled monthly for shrimp and fin fish during six months, from December 2001 to May 2002, using small boats fitted with outboard engines and the three fishing gears employed by shrimp fishermen in the

F Amezcua; J Madrid-Vera; H Aguirre-Villaseñor


An Application Example of the Landsat Data to the Study of the Relationship Between the Topography and Pasture Quality in Areas of Paragominas Exemplo de Aplicacao de Dados Do Sistema Landsat, No Estudo das Relacoes Entre Compartimentacao Topografica E Qualidade de Pastagens No Municipio de Paragominas (Pa).  

National Technical Information Service (NTIS)

The relationship between pasture quality and geomorphology was verified by applying visual and automatic interpretation techniques to LANDSAT data. The results show that LANDSAT data is useful to point out better areas to settle pastures.

N. Dejesusparada A. P. Dossantos E. M. L. Demoraesnovo V. Duarte



Ontogenese da somatostatina no sistema gastro-entero-pancreatico: estudo realizado em ratos normais e no curso de um diabete experimental provocado em ratos recem-nascidos. (Somatostatin ontogenesis in the gastrointestinal and pancreatic tract: study in normal rats and during induced diabetes in neonatal rats).  

National Technical Information Service (NTIS)

The ontogenic studies of somatostatin of pancreas, ileum and duodenum of Wistar rats and the rats with induced diabetes were done. The radioimmunologic method to dose the somatostatin was used. (L.M.J.). (Atomindex citation 23:025576)

M. C. Cunha



Workshop Nazionale (6th) Enter-Net Italia Sistema di Sorveglianza delle Infezioni Enteriche. Le Tossinfezioni Alimentari: Sorveglianza e Controllo, Roma, Maggio 17-18, 2007. Riassunti (National Workshop (6th) Enter-Net Italia. Surveillance System of Enteric Infections. Foodborne Infections: Surveillance and Control. Held in Rome on May 17-18, 2007. Abstract Book).  

National Technical Information Service (NTIS)

Enter-net is an international network for the surveillance of human infections with Salmonella, E. coli O157 and Campylobacter, including their antimicrobial resistance. It is funded by the European Commission and its main objectives are the harmonisation...



Citta di Serres, Grecia. Studio di Fattibilita di un Sistema di Teleriscaldamento con Utilizzo di Lignite di Produzione Locale. Vol. 1: Relazione Generale. Vol. 2: Disegni (Municipality of Serres, Greece. Feasibility Study for a District Heating System Using Locally-Produced Lignite. Vol. 1: Report. Vol. 2: Figures).  

National Technical Information Service (NTIS)

The study examines the possibilities to use lignite as a source of energy for space heating instead of geothermal energy, in the Greek town of Serres. Two different solutions using lignite were studied: the use of lignite in housing block-sized boilers; t...



Molecular characterization of lactic acid bacteria isolated from beef and stored using vacuum-packaging and advanced vacuum skin packaging systems Caracterización molecular de bacterias ácido-lácticas aisladas a partir de carne de ternera envasada al vacío de modo tradicional y mediante un sistema avanzado  

Microsoft Academic Search

A total of 91 lactic acid bacteria (LAB) were isolated from 50 beef samples, 25 packaged by traditional vacuum packaging and 25 packaged using advanced vacuum skin packaging. The isolated LAB were identified using 16S rRNA sequencing, whereas randomly amplified polymorphic DNA (RAPD-PCR) and cluster analysis were used for typing the LABs. Ten different species of LAB were identified and

A. Samuel; J. M. Miranda; M. Guarddon; C. G. Nebot; M. P. Calo-Mata; A. Cepeda; C. M. Franco



Estudio Integral de Desarrollo e Inversiones del Sistema Aeroportuario y de Rutas Aereas de Venezuela. Fase 1. Informe Final. Volumen 1 (Comprehensive Study of the Development and Investment Requirements of the Airspace and Airport System of Venezuela. Phase 1. Volume 1).  

National Technical Information Service (NTIS)

The report, written in Spanish, presents the results of a Feasibility Study prepared by AAROTEC/Airways Engineering Associates and Louis Berger International for the Ministry of Transportation and Communications of Venezuela. The report discusses the expa...



ADUBAÇÃO COM SILÍCIO COMO F ATOR DE RESISTÊNCIA A INSETOS-PRAGA E PROMOTOR DE PRODUTIVIDADE EM CULTURA DE BA TATA INGLESA EM SISTEMA ORGÂNICO Fertilization with silicon as resistance factor to pest insects and promoter of productivity in the potato crop in an organic system  

Microsoft Academic Search

-1 ; 3- adubação via foliar com solução de ácido silícico a 0,35%; 4- adubação via solo com pó de rocha, na dose correspondente a 2t.ha -1 ; 5-adubação via foliar com solução de pó de rocha a 2%. Os tratamentos foram aplicados 20 dias após o plantio da batata-semente. Foi monitorada a incidência de insetos-praga por meio da determinação

Flávia Batista Gomes; Jair Campos Moraes; Danila Kelly; Pereira Neri



Resistência à fadiga flexuRal dos sistemas RotatóRios k3 e Race em Razão do uso FlexUR al FatigUe ReSiStanCe OF ROtaR y Sy StemS and k3 RaCe beCaUSe OF the USe  

Microsoft Academic Search

Introduction: The aim of this work was to evaluate the cyclic fatigue resistance of two different nickel-tita - nium rotary systems, k3 (Sybron Endo, EUA) and Endosequence (Brasseler, EUA), based on the number of uses. All rotary files which were selected had their conicity of 0,04, 25mm of length and tip diameter of 25, following ISO standardization. Methods: To reach

Luís César Brisighello; Giulio Gavini; Guilherme Augusto Figueiredo; Danilo Minor Shimabuko


RESUMEN DE TESIS DOCTORAL Reconstrucción de Parámetros y Variables de Estado para una Clase de Sistemas Caóticos con Aplicación en Codificación y Decodificación de Información Parameter and State Variable Reconstruction for a Class of Chaotic with Application to Information Codification and De-codification  

Microsoft Academic Search

In this paper we describe how to use exact state and parametric integral equations re-constructors for the identification of the state variables of dynamic chaotic discrete and continuous non-lineal systems. In both cases, we avoid the use of asymptotic observers and Takens Theorem. Identification and reconstruction of discrete systems is illustrated with Lozi's system. The state reconstruction schema for discrete

Miguel Santiago; Suárez Castañón; Carlos Fernando Aguilar Ibáñez



Estudio de los intercambios de calor y masa entre un invernadero considerado como colector de aire humedo y un lecho de rocas como sistema de control ambiental. (Study on heat and mass transfer between a greenhouse considered as a solar air heater and a rock packed bed as ambient control system).  

National Technical Information Service (NTIS)

A general study on heat transfer in dry packed beds is made, with special emphasis in comparing different transient models and in identifying the required conditions by which the attained results are equivalent. The differences in thermal behaviour on pac...

J. I. Ajona Maeztu



Estudio de los intercambios de calor y masa entre un invernadero considerado como colector solar de aire humedo y un lecho de rocas como sistema de control ambiental. (Study on heat and mass transfer between a greenhouse considered as a solar air heater and a rock packed bed as ambient control system).  

National Technical Information Service (NTIS)

A general study on heat transfer in dry packed beds is made, with special emphasis in comparing different transient models and in identifying the required conditions by which the attained results are equivalent. The differences in thermal behaviour on pac...

J. I. Ajona Maeztu



Urbanization and the groundwater budget, metropolitan Seoul area, Korea  

NASA Astrophysics Data System (ADS)

The city of Seoul is home to more than 10 million people in an area of 605 km2. Groundwater is ed for public water supply and industrial use, and to drain underground facilities and construction sites. Though most tap water is supplied from the Han River, the quantity and quality of groundwater is of great concern to Seoul's citizens, because the use of groundwater for drinking water is continuously increasing. This study identifies the major factors affecting the urban water budget and quality of groundwater in the Seoul area and estimates the urban water budget. These factors include leakage from the municipal water-supply system and sewer systems, precipitation infiltration, water-level fluctuations of the Han River, the subway pumping system, and domestic pumping. The balance between groundwater recharge and discharge is near equilibrium. However, the quality of groundwater and ability to control contaminant fluxes are impeded by sewage infiltration, abandoned landfills, waste dumps, and abandoned wells. Résumé. La ville de Séoul possède une population de plus de 10 millions d'habitants, pour une superficie de 605 km2. Les eaux souterraines sont pompées pour l'eau potable et pour les usages industriels, ainsi que pour drainer les équipements souterrains et les sites en construction. Bien que l'essentiel de l'eau potable provienne de la rivière Han, la quantité et la qualité de l'eau souterraine présentent un grand intérêt pour les habitants de Séoul, parce qu'on utilise de plus en plus l'eau souterraine pour l'eau potable. Cette étude identifie les facteurs principaux qui affectent la qualité de l'eau souterraine dans la région de Séoul et fait l'estimation du bilan d'eau urbaine. Les principaux facteurs affectant le bilan d'eau urbaine et la qualité de l'eau souterraine sont les fuites du réseau d'adduction et du réseau d'égouts, l'infiltration des eaux de précipitation, les fluctuations du niveau de la rivière Han, le réseau de pompage du métro et les pompages privés. Le bilan entre la recharge de la nappe et sa décharge est proche de l'équilibre. Cependant, les infiltrations d'eaux usées, les décharges abandonnées, les décharges d'ordures et les puits abandonnés portent atteinte à la qualité de l'eau souterraine et à la capacité de contrôler les flux de contaminants. Resumen. La ciudad de Seúl tiene más de 10 millones de habitantes en un área de 605 km2. Se bombea aguas subterráneas para abastecimiento urbano y para usos industriales, así como para el drenaje de instalaciones subterráneas y de solares en construcción. Aunque la mayor parte del agua de boca procede del río Han, los ciudadanos de Seúl están muy concienciados por la cantidad y calidad de las aguas subterráneas, ya que su explotación para uso de boca está experimentando un continuo incremento. El presente estudio identifica los factores que más afectan a la calidad de las aguas subterráneas en el área de Seúl y hace una estimación del balance de agua en el territorio urbano. Entre los factores principales que afectan al balance y a la calidad de las aguas subterráneas, se incluye el lixiviado de la red municipal de suministro y de la red de alcantarillado, la infiltración de agua de lluvia, las fluctuaciones del nivel del río Han, el sistema de bombeo del metro y los bombeos domésticos. El balance entre la recarga y la descarga en el acuífero está próximo al equilibrio. Sin embargo, la calidad de las aguas subterráneas y la capacidad de controlar los flujos de contaminación están amenazadas por la infiltración de aguas residuales, vertederos abandonados, depósitos de residuos y pozos abanadonados.

Kim, Yoon-Young; Lee, Kang-Kun; Sung, Ig Hwan



Measurement and evaluation of national family planning programs.  


RESUMEN: En los últimos quince años diez paises han inaugurado programas nacionales de planeamiento familiar: India, Pakistán, Corea del Sur, Taiwan, Turquía, Malasia, Ceilán, Túez, la República Arabe Unida, y Marruecos. Otros paises, incluyendo Tailandia, Hong Kong, Singapur, Kenya, Barbados, Trinidad y los Estados Unidos, apoyan y/o estimulan actividades de planeamiento familiar. En la mayor parte de los casos la razón fundamental del programa ha sido que si la tasa de crecimiento poblacional disminuyera, aumentaría la tasa de crecimiento económico.Las metas de largo alcance, expresadas típicamente en términos de reducir las de natalidad o de crecimiento, tienen su ejemplo en el propósito de Pakistán de reducir su tasa de crecimiento a 26 para 1970; el de Corea de reducir su tasa de natalidad a 20 para 1971; y el de India de reducir su tasa de natalidad a 25 para 1973.Los objectivos intermedios, que cubren diversos aspectos del pro grama, incluyen metas específicas para un determinado mes a año, considerando personal, la adquisición de anticonceptivos, y el número de usarios por método. Las metas específicas anuales de aceptantes de dispositivos intrauterinos (IUD), para Taiwán, Corea, Túnez, Pakistán e India, son comunes, tanto por la naturaleza del artefacto, como por la facilidad de medición de los que continúan utilizándolos. El programa de evaluación en Taiwán, que trata de medir por diversos medios los efectos inmediatos, mediatos y de largo plazo del programa de planeamiento familiar sirve de modelo. El propósito de la evaiuación de un programa de planeamiento familiar es contribuir a la efectividad y eficiencia del programa, midiendo y analizando su progreso. Las áreas a medir pueden ser clasificadas como- (1) conocimiento acerca de; (2) actitudes hacia; (3) práctica de control de natalidad; y (4) nivel de fecundidad.Un buen sistema de evaluación debería incluir: A. Un buen conjunto de estadísticas de servicio presentadas en formularios estandarizados, en las siguienies formas: 1. Informes nensuales por áreas administrativas, sobre los actuales servicios de planeamiento familiar proporcionados en la actualidad, de carácter permanente o de larga duración (al presente, esterilización y IUD de acuerdo a las siguientes características del receptor: residencia, edad, paridad (número de hijos vivos por sexo), y donde se enteró del programa, si es posible "clase";(probablemente educación de la madre, pero posiblemente ocupación del esposo, ingreso, o equivalente); prácticas anticonceptivas anteriores; intervalo; y deseo de tener más hijos. En un programa grande estos datos pueden obtenerse en base a una muestra. 2. Informes mensuales sobre la distribución de suministros anticonceptivos (condones, píldoras, sustancias efervescentes, etc.), los primeros suministros deben ir acompañados de un registro de las características del recipiente, como anteriormente; los suministros subsecuentes se regietrarán sólo en volumen bruto. Esto también se aplicará al ritmo, donde éste método se enseñe a un número considerable de mujeres. 3. Informes regulares sobre las actividades de planeamiento familiar de médicos privados, como una estimación del efecto catalítico del programa del gobierno sobre ci sector privado. 4. Datos generates mensuales, ppr áreas admirtistrativas importantes, sabre: visitas domiciliarias, reuniones, cuñas radiates y televisadas, avisos en los periódicos y personal que trabaja. 5. Para propósitos de seguimiento una entrevi eta de campo cada 6 a 12 meses a cada N mujer de las listas para (1) y (2) arriba, en un total de 300 o 400, para conocer las tasas de continuación y las razones de abandono (ej: desea otro hijo, insatisfecha can ci método, otras). Las mue.stras podrían ser de 300 cada una, con una supuesta experiencia de 6, 12, 18 y 24 meses. B. Un buen conjunto de datos sobre costa (datos sobre cotos actulaes atribuíbles directamente al programa de planeamiento familiar) fraccionados par áreas principales y cinco a seis

Mauldin, W P



Progresos recientes en Astronomía de Rayos Gamma  

NASA Astrophysics Data System (ADS)

Tras la exitosa misión del Compton Gamma-Ray Observatory durante los años 1990, la astronomía de rayos gamma ha entrado en una etapa de madurez, convirtiéndose en una de las principales herramientas para el estudio de procesos relativistas en el universo. En este reporte, presentaré una revisión de los principales tópicos abordados a través de estudios con rayos gamma en los últimos años, con particular énfasis en los intentos más recientes por establecer la naturaleza de las fuentes de rayos gamma no identificadas, detectadas por el instrumento EGRET.

Romero, G. E.


La estructura de mercado del sector de las artes escénicas en España  

Microsoft Academic Search

La diversidad de agentes y de comportamientos, así como la complejidad que encierra la existencia e interrelación de dos mercados, el de la producción y el de la difusión, han dificultado el estudio del sistema escénico español desde perspectivas científicas. Con el objetivo de cubrir parcialmente ese vacío y presentar las especificidades de dicho sistema, el presente trabajo utiliza el




Aplicación de un Enfoque Intencional al Análisis de Variabilidad  

Microsoft Academic Search

El interés por el estudio de la variabilidad, es decir la habilidad de cambio o adaptación de un sistema, ha aumentado significativamente durante los últimos años. Esto se debe a su utilidad en diversos campos, desde la personalización del software a las líneas de producto o la adaptación automática de sistemas. Dicho estudio ha estado centrado principalmente en cuestiones de

Bruno González-Baixauli; Miguel A. Laguna; Sampaio do Prado




Microsoft Academic Search

Resumo? Durante os últimos anos, a evolução das redes fieldbus, em conjunto com a simplificação das redes tradicionais de computadores, permitiu a integração de diferentes sistemas de comunicação tanto dentro das células de produção, quanto entre células de produção e outros sistemas para gerência inteligente, supervisão e controle. Várias tecnologias de comunicação já existem atualmente para redes públicas e não-públicas




Microsoft Academic Search

El presente trabajo analiza a grandes rasgos, una parte de la reforma fiscal en el 2010, como una herramienta emergente para lograr el crecimiento, hoy cuando el actual sistema fiscal resulta complicado, inefectivo, -y en el que además se estima que tiene un 40 por ciento de evasión fiscal,- ha sido propuesto un nuevo sistema tributario que permite generar mayores

Oscar González Muñoz



The nature of the chemical bond  

Microsoft Academic Search

As condições básicas que devem ser satisfeitas por qualquer função de onda representando um sistema polieletrônico são apresentadas e discutidas. Em seguida, examinamos como construir funções de onda para sistemas polieletrônicos que satisfaçam àquelas condições e analisamos as condições sob as quais os conceitos clássicos de estrutura molecular, estrutura química e de ligação química podem ser traduzidos para a mecânica

Marco Antonio Chaer Nascimento



Los cronómetros, la luz y la transformación de coordenadas espacio-temporales  

Microsoft Academic Search

RESUMEN. En este trabajo se obtienen las ecuaciones de transformación relativista para longitudes y tiempos, basándose en el hecho de que la medida de un intervalo temporal o espacial debe ser expresada por dos factores: valor y unidad de medida. Una técnica de doble subíndice permite distinguir en cuál sistema se hace la medida y a cuál sistema se refiere




La política de vivienda de interés social en Colombia en los noventa  

Microsoft Academic Search

Este trabajo analiza el desarrollo de la política de vivienda de interés social en Colombia a partir de 1991, cuando se adoptó el sistema de subsidios a la demanda. Este sistema sustituyó al antiguo esquema en el cual el Estado era directamente constructor de viviendas, proveedor de créditos y de subsidios. La nueva política persigue incrementar la demanda efectiva de

María Luisa Chiappe de Villa



Dinámica de planetas extrasolares resonantes  

Microsoft Academic Search

Actualmente se han detectado 117 planetas alrededor de estrellas de Secuencia Principal, incluyendo 12 sistemas planetarios, cada uno con dos o tres miembros. De estos últimos, ocho poseen planetas en órbitas próximas y sus perturbaciones gravitacionales se convierten en un factor fundamental para la estabilidad orbital del sistema. Todos se encuentran en configuraciones resonantes, desde la conmensurabilidad de movimientos 2\\/1

C. Beauge




Microsoft Academic Search

A big size ram-air parachute was designed and manufactured by CIMSA Ingeniería de Sistemas within the frame of the FASTWing Project. CIMSA Ingeniería de Sistemas has joined efforts together with a consortium of companies from the European Union: Autoflug GmbH - Germany, CESA - Spain, CFD - Norway, DLR - Germany, EADS-ST - Germany, NLR - The Netherlands, for the

S. Benolol; F. Zapirain


El permiso de paternidad y la desigualdad de género. Propuestas de reforma para el caso de España  

Microsoft Academic Search

En el presente artículo se propone que se introduzcan en España reformas de cierto alcance en su sistema de permisos de maternidad y de paternidad, de manera que se consiga la plena igualdad entre ambos, como ya sucede en países como Alemania o Islandia. En concreto, se defiende un sistema de permisos que conste de permisos de maternidad y de

Rocío Albert López-Ibor; Lorenzo Escot Mangas; Carlos Poza Lara



Impacto de las Tecnologías de la Información y las Comunicaciones (TIC) en el desarrollo y la competitividad del país  

Microsoft Academic Search

La primera parte de este estudio caracteriza al sector de telecomunicaciones en Colombia, comparando a Colombia con otros países y regiones del mundo, mostrando la evolución de algunos de los principales indicadores de telecomunicaciones. En la segunda parte se hacen estimaciones cuantitativas del impacto socioeconómico del sector en la economía colombiana, a través de dos herramientas: la metodología insumo-producto y

Juan Benavides; Felipe Castro; Lina Devis; Mauricio Olivera



Les comptes de l'agriculture de l'année 1974  

Microsoft Academic Search

[fre] Après 1973, année de très forte croissance des productions, des prix et du résultat brut d'exploitation agricoles, l'année 1974 est marquée par une stagnation du volume de la production (+ 0,3 %) due principalement aux mauvaises conditions climatiques. La hausse des prix a été modérée (+ 4,4 %), elle reste très liée aux conditions des marchés mondiaux. Malgré la




Microsoft Academic Search

E n s a y o En este artículo se discuten algunos de los principales aspectos a considerar al momento de abordar el análisis del mercado de los servicios de salud. Las consideraciones conceptuales se refieren tanto a la demanda como a la oferta, aunque el análisis pudiera centrarse en algunos momentos hacia la demanda. Por otra parte, las mismas

Arredondo López; Recaman Mejía



Microsoft Academic Search

RESUMEN: La aglomeración urbana del centro de Asturias, que se encuentra entre las principales de España y a la que denominamos Ciudad Astur, constituye un fenómeno territorial de gran trascendencia, en fase de consolidación y de transformación de simple aglomeración en ciudad. Su consideración como factor clave para el desarrollo regional y para la articulación del territorio regional requiere su

Fermín Rodríguez Gutiérrez; Rafael Menéndez Fernández


A través de los ojos de Carl Marx: reseña de los escritos de Marx sobre América Latina en Alberto Fillipi  

Microsoft Academic Search

La historia de las instituciones latinoamericanas es compleja, densa y ambivalente. Italiano de nacimiento, pero venezolano por opción; el profesor Alberto Fillipi es considerado como uno de los principales estudiosos de las instituciones latinoamericanas en el mundo. En su obra, Las Instituciones e Ideologías en la Independencia Hispanoamericana, Fillipi recoge un conjunto de ensayos los cuales fueron escritos en diferentes

Maximiliano Korstanje




Microsoft Academic Search

Los enfoques existentes sobre la filosofía del turismo descansan en tres elementos principales interrelacionados entre sí: el turista, su medio de locomoción y el anfitrión que lo recibe. La realidad ontológica del fenómeno se funda sobre una de las necesidades humanas de evasión y descanso. Según la bibliografía especializada, la división del trabajo impone cierta disciplina de la cual el

Maximiliano Korstanje




Microsoft Academic Search

Este artículo resume la utilización de una página web como complemento de los medios tradicionales (impresos y audiovisuales), empleado para el desarrollo del proceso de enseñanza-aprendizaje de la disciplina Sanidad Vegetal en la formación de ingenieros agrónomos. Como principales resultados se contribuye al logro de las habilidades necesarias propias de la disciplina, las cuales son indispensables para el futuro profesional

Carlos Pupo Feria; Gladia González Ramírez



Educación superior e ingresos laborales: Estimaciones paramétricas y no paramétricas de la rentabilidad por niveles y carreras en el Perú  

Microsoft Academic Search

Si relacionamos el logaritmo del ingreso laboral con los años de educación a través de una especificación “minceriana” tradicional obtenemos que, en el Perú, el rendimiento de un año adicional de educación sería del orden del 10%. En la primera parte de este estudio, sin embargo, encontramos que los principales supuestos que permiten relacionar este porcentaje con el concepto de

Gustavo Yamada; Juan F. Castro



Reproduccion del ganado  

Technology Transfer Automated Retrieval System (TEKTRAN)

La determination de prenez es una de las principales herramientas de manejo en el Ganado de came. Le habilidad de determiner prenez proporciona al productor un medio de tomar sus decsiones de seleccion y descartarte en momentos decisivos, enfocando los recursos de la operacion en reporductores confi...



Microsoft Academic Search

Los países menos favorecidos de América Latina se resisten a las nuevas recetas económicas impuestas por las naciones más ricas, y se enfrentan a un peligroso contexto internacional asociado a notables cambios que están produciéndose en las concepciones sobre relaciones políticas internacionales, como parte de las acciones impulsadas por las principales potencias para estructurar un nuevo orden mundial acorde con

Eyedelkis Medina García; Ileana Jáñez Reyes; Maricel Batalla Barcelay; Ricardo Rey Riquenes




Microsoft Academic Search

La principale technologie financière de l'Inde ancienne, qui a été utilisée depuis toujours, est le « chit fund ». C'est une technique qui permet aux membres de déposer leur épargne à certaines échéances (dans un lapse de temps déterminé) et d'être remboursés du montant déposé à la fin de la période considérée. Une clause est prévue selon laquelle les dépôts

C. P. S. Nayar




Microsoft Academic Search

El objetivo de este trabajo es presentar a la comunidad petrolera una síntesis de los principales resultados de dos líneas de investigación aplicada llevadas a cabo en sitios severamente degradados por la explotación de hidrocarburos. Ecología de disturbios. A fin de evaluar los procesos de regeneración natural post-disturbio se investigaron, durante febrero-marzo de 2002 y mediante un diseño de muestras

G. A Zuleta; L. G. Reichmann; M. C. Li Puma



Microsoft Academic Search

La técnica fotoacústica es un método muy sensible para la detección de trazas gaseosas en el estudio de la contaminación ambiental y otras aplicaciones. Uno de los principales problemas que presenta es el proceso de adsorción-desorción, presente en el caso de moléculas polares como el agua, el amoníaco o el dióxido de nitrógeno, que produce importantes variaciones en las muestras

A. L. Peuriot; G. D. Santiago; V. B. Slezak; M. G. González


Blanqueo de capitales y lavado de dinero: su concepto, historia y aspectos operativos  

Microsoft Academic Search

Hoy en día el lavado o reciclaje de dinero es percibido por la comunidad internacional como uno de los principales problemas, frente al cual la actividad criminal ocupa la atención de todas las autoridades relacionadas con el tema. Los países son conscientes de la difícil situación de establecer un criterio uniforme precisamente porque las realidades de cada nación son diversas

Bruno Tondini


L'intérêt d'un renforcement des fonds propres bancaires (et de mesures complémentaires) pour concilier stabilité financière, performance et bon fonctionnement des banques  

Microsoft Academic Search

Les banques ont entre autres vocations à collecter les dépôts. Ces dépôts représentent leur principale source de financement et jouent un rôle important (à la fois théoriquement et empiriquement) sur leur bon fonctionnement. Il semble donc normal que les banques aient un niveau de levier relativement élevé. Néanmoins, le fort levier des banques génère des externalités négatives pour l'ensemble de

Arthur Petit-Romec




Microsoft Academic Search

En este documento se presenta un Índice de Precios de Vivienda Usada (IPVU) para Colombia (1988 y 2004), calculado a partir de una adaptación de la metodología de ventas repetidas ponderadas propuesta por Case y Shiller (1989). En su construcción se usaron 26.189 avalúos de las mismas viviendas en distintos periodos de tiempo, según la información suministrada por las principales

Julio Escobar; Carlos Huertas; Dora Alicia Mora; José Vicente Romero


Une équipe de recherches face aux problèmes de développement  

Microsoft Academic Search

[fre] A la demande des organisations professionnelles des Vosges, une équipe de recherches pluridisciplinaire a été constituée en vue d'analyser les principaux problèmes posés par le choix d'une politique de développement agricole pour ce département. . Après avoir rappelé les principales étapes de la démarche suivie par l'équipe de recherche (études analytiques, essai de synthèse présentée sous forme de «

M. Petit; J.-P. Deffontaines; A. Brun; P.-L. Osty




Microsoft Academic Search

Sommario Scopo principale del presente lavoro è di analizzare e descrivere lo schema di funzionamento e lo stato tensionale di accoppiamenti albero mozzo realizzati per serraggio e presenti nelle sospensioni anteriori motociclistiche. Sono stati analizzati sia gli accoppiamenti tra il trapezio ed il gambale della sospensione (morsetti trapezio), realizzati mediante l'impiego di una o due viti di serraggio, sia gli

D. Croccolo; R. Cuppini; N. Vincenzi


La virtualización del cuerpo a través del \\  

Microsoft Academic Search

Hablar de un cuerpo virtualizado es hablar de su problematización y consecuente actualización, una de las principales consecuencias de este proceso de transfiguración del cuerpo estaría marcada por una adjudicación actualizada de un cambio. El cuerpo es simultáneamente un cuerpo-materia prima, modelo físico para la conversión óptico-iconográfica digital, y un cuerpo interfaz, que permite el acceso a la morfogénesis del

Eduardo Castro Pinzón; José Luis Troncoso



Analyse de l'intermodalité fret en Suisse  

Microsoft Academic Search

Cet article fournit une analyse du transport intermodal en Suisse. Il fait partie de la série d'expertises indépendantes effectuées pour l'Observatoire des Politiques et Stratégies de Transport en Europe. La principale composante du trafic intermodal en Suisse est le transit international (90%), où le trajet Nord- Sud domine nettement. Ce transit est réparti en parts relativement égales entre le transport




LOS HISPANOS Y EL CÁNCER DE PÁNCREAS: COSAS PARA SABER por el Instituto Nacional del Cáncer Una de las causas principales de muerte relacionadas con el cáncer en los hispanos o latinos de los Estados Unidos es una enfermedad poco común pero con frecuencia



Microsoft Academic Search

Entre los problemas medioambientales actuales, la reducción o eliminación de los residuos se ha convertido en una de las principales preocupaciones en los países industrializados y en una prioridad para las empresas. En el presente trabajo se realiza una revisión de los postulados del modelo económico clásico, vigente hasta hace escasas fechas, en relación con la variable medio ambiente y

Unai Tamayo Orbegozo; María Azucena Vicente Molina; Julen Izaguirre Olaizola




Microsoft Academic Search

En los últimos años en nuestro país, ha venido cobrando especial relevancia el sector de los micros, pequeñas y medianas empresas (MIPyMES); las estrategias principales del gobierno, están enfocadas precisamente en el apoyo a este sector, que sustenta las cifras actuales de empleo. Sin embargo las condiciones económicas y financieras del entorno han generado un alto grado de incertidumbre, los

Nicolás Barajas-Andrade; Eugenio Guzmán-Soria; Juvencio Hernández-Martínez; Samuel Rebollar-Rebollar




Microsoft Academic Search

RESUMEN Datos diarios de temperaturas máximas y mínimas del aire fueron usados para determinar las unidades calor, que sirvieron como referencia para definir las principales etapas fenológicas en seis tipos diferentes de chile (Capsicum annuum). Las unidades calor sirvieron para inferir el período de mayor requerimiento de nutrimentos, así como la relación con la sintomatología de las enfermedades más importantes

Salvador Montes Hernández; Elena Heredia García; J. Alfonso; Aguirre Gómez


Competencias social y habilidades sociales en la Educación Especial  

Microsoft Academic Search

La enseñanza y el aprendizaje de habilidades sociales específicas es uno de los principales propósitos que se plantea la Educación Especial, con objeto de que los alumnos adquieran la suficiente competencia social que les permita una plena integración en la comunidad. Muchos han sido los procedimientos utilizados para su instrucción; la mayoría de estos métodos han ejercido influencias beneficiosas en




Ulteriori sviluppi della teoria diametrale delle superficie algebriche  

Microsoft Academic Search

Riassunto  Si precisa la forma dell'equazione di una superficie algebrica con punto principale proprio, improprio o indeterminato e si\\u000a stabilisce inoltre il numero dei piani diametrali principali di una superficie algebrica qualunque determinando i tipi di\\u000a superficie algebriche che ne possiedono infiniti.

B. A. Rosina



Correlación entre la estructura de bandas y las propiedades físicas de óxidos cerámicos de estructura perovskita con metales de transición (I): Propiedades de conducción electrónica  

Microsoft Academic Search

En este artículo se revisa los principales modelos teóricos, que pretenden dar una explicación sobre las propiedades de con- ducción electrónica de óxidos cerámicos con estructura perovskita, que incluyen en la posición B metales de transición del primer período (Fe, Co, Ni, Mn), en conexión con su estructura de bandas y el carácter de sus electrones más externos, así como



Um supressor de fundo térmico para a câmara infravermelha CamIV  

NASA Astrophysics Data System (ADS)

O ângulo sólido subtendido pelos pixels na câmara infravermelha do NexGal (CamIV) que operamos no OPD/LNA contém contribuições provenientes do sistema de coleta de fluxo propriamente dito - sendo esta a parte que interessa para as medidas astronômicas - e contribuições da obstrução central, sistema de suporte do espelho secundário e região exterior à pupila de entrada do telescópio. Estas últimas contribuições são devi-das à emissão de corpo negro à temperatura ambiente e aumentam exponencialmente para comprimentos de onda maiores que 2 micra (banda K, no infravermelho próximo). Embora a resultante pode ser quantificada e subtraída dos sinais relevantes, sua variância se adiciona à variância do sinal, e pode ser facilmente a contribuição domi-nante para a incerteza final das medidas, tornando ineficiente o processo de extração de informação e degradando a sensibilidade da câmara. A maneira clássica de resolver esse problema em sistemas ópticos que operam no infravermelho, onde os efeitos da emissão térmica do ambiente são importantes, é restringir o ângulo sólido subtendido pelos pixels individuais exclusivamente aos raios provenientes do sistema óptico. Para tanto, projeta-se uma imagem real, bastante reduzida, da pupila de entrada do sistema óptico num anteparo que transmita para o sistema de imageamento só o que interessa, bloqueando as contribuições das bordas externas à pupila de entrada, obstrução central do telescópio e sistema de suporte. Como a projeção é realizada em ambiente criogênico, a contribuição térmica espúria é efetivamente eliminada. Nós optamos por um sistema do tipo Offner para implementar na prática esta função. Trata-se de um sistema baseado em espelhos esféricos, bastante compacto e ajustado por construção. A opção por espelhos do mesmo material que o sistema de suporte (Alumínio) minimiza a dilatação diferencial, crítica nesse tipo de aplicação. Apresentamos as soluções detalhadas do projeto óptico-mecânico, bem como uma análise de flexões e desempenho em termos de qualidade de imagem.

Jablonski, F.; Laporte, R.



A novel method to prepare L-Arabinose from xylose mother liquor by yeast-mediated biopurification  

PubMed Central

Background L-arabinose is an important intermediate for anti-virus drug synthesis and has also been used in food additives for diets-controlling in recent years. Commercial production of L-arabinose is a complex progress consisting of acid hydrolysis of gum arabic, followed by multiple procedures of purification, thus making high production cost. Therefore, there is a biotechnological and commercial interest in the development of new cost-effective and high-performance methods for obtaining high purity grade L-arabinose. Results An alternative, economical method for purifying L-arabinose from xylose mother liquor was developed in this study. After screening 306 yeast strains, a strain of Pichia anomala Y161 was selected as it could effectively metabolize other sugars but not L-arabinose. Fermentation in a medium containing xylose mother liquor permitted enrichment of L-arabinose by a significant depletion of other sugars. Biochemical analysis of this yeast strain confirmed that its poor capacity for utilizing L-arabinose was due to low activities of the enzymes required for the metabolism of this sugar. Response surface methodology was employed for optimization the fermentation conditions in shake flask cultures. The optimum conditions were: 75 h fermentation time, at 32.5°C, in a medium containing 21% (v/v) xylose mother liquor. Under these conditions, the highest purity of L-arabinose reached was 86.1% of total sugar, facilitating recovery of white crystalline L-arabinose from the fermentation medium by simple methods. Conclusion Yeast-mediated biopurification provides a dynamic method to prepare high purity of L-arabinose from the feedstock solution xylose mother liqour, with cost-effective and high-performance properties.



Expansion of Monocytic Myeloid-Derived Suppressor Cells Dampens T Cell Function in HIV-1-Seropositive Individuals  

PubMed Central

T lymphocyte dysfunction contributes to human immunodeficiency virus type 1 (HIV-1) disease progression by impairing antivirus cellular immunity. However, the mechanisms of HIV-1 infection-mediated T cell dysfunction are not completely understood. Here, we provide evidence that expansion of monocytic myeloid-derived suppressor cells (M-MDSCs) suppressed T cell function in HIV-1-infected individuals. We observed a dramatic elevation of M-MDSCs (HLA-DR?/low CD11b+ CD33+/high CD14+ CD15? cells) in the peripheral blood of HIV-1-seropositive subjects (n = 61) compared with healthy controls (n = 51), despite efficacious antiretroviral therapy for nearly 2 years. The elevated M-MDSC frequency in HIV-1+ subjects correlated with prognostic HIV-1 disease markers, including the HIV-1 load (r = 0.5957; P < 0.0001), CD4+ T cell loss (r = ?0.5312; P < 0.0001), and activated T cells (r = 0.4421; P = 0.0004). Functional studies showed that M-MDSCs from HIV-1+ subjects suppressed T cell responses in both HIV-1-specific and antigen-nonspecific manners; this effect was dependent on the induction of arginase 1 and required direct cell-cell contact. Further investigations revealed that direct HIV-1 infection or culture with HIV-1-derived Tat protein significantly enhanced human MDSC generation in vitro, and MDSCs from healthy donors could be directly infected by HIV-1 to facilitate HIV-1 replication and transmission, indicating that a positive-feedback loop between HIV-1 infection and MDSC expansion existed. In summary, our studies revealed a novel mechanism of T cell dysfunction in HIV-1-infected individuals and suggested that targeting MDSCs may be a promising strategy for HIV-1 immunotherapy.

Qin, Aiping; Cai, Weiping; Pan, Ting; Wu, Kang; Yang, Qiong; Wang, Nina; Liu, Yufeng; Yan, Dehong; Hu, Fengyu; Guo, Pengle; Chen, Xiaoping; Chen, Ling; Zhang, Hui



Evaluation of Camellia sinensis catechins as a swine antimicrobial feed additive that does not cause antibiotic resistance.  


Antimicrobial growth promoters (AGPs) have been banned and phased out because their use has been linked to the emergence and spread of antibiotic-resistant pathogens; however, the ban has had a marked impact on livestock production, and feed additive alternatives to AGPs are required. We focused on green tea leaves as potential alternatives to AGPs because they contain significant amounts of polyphenol catechins, which have antivirus and antimicrobial effects. We examined cross-resistance between epigallocatechin gallate (EGCG), which is the most abundant catechin of green tea leaves, and commercially available antimicrobials in clinically problematic antimicrobial-resistant bacteria, and whether bacteria have the ability to acquire resistance by consecutive passage in sub-inhibitory concentrations of EGCG. EGCG did not display any cross-resistance with reference antimicrobials and the bacteria did not acquire EGCG resistance. Further, we examined the growth-promoting effects of dried green tea leaves on the breeding of a new Japanese breed, Tokyo-X pigs. While the mortality rates of the green tea leaf (GTL) and AGP groups were both 11.1% (one in nine piglets), the mortality rate was 50% for the control group with an additive-free diet (four in eight piglets). The rate of body weight increase in both the GTL and AGP groups was approximately the same. The growth-promoting effects of green tea leaves and AGPs were similar, and there was no possibility that the antimicrobial properties of catechins caused the same problem as AGPs. Thus, it can be concluded that green tea leaves are a safe feed additive alternative to AGPs. PMID:23138151

Ohno, Akira; Kataoka, Shinichiro; Ishii, Yoshikazu; Terasaki, Toshiaki; Kiso, Masaaki; Okubo, Mitsuyuki; Yamaguchi, Keizo; Tateda, Kazuhiro



Mutation analysis of hepatitis B virus reverse transcriptase region among untreated chronically infected patients in Ahvaz city (South-West of Iran).  


Background: It has been revealed that mutations can occur spontaneously and naturally in HBV reverse transcriptase (RT) region among untreated patients. These HBV mutants pre-exist as minor viral population in naive patients and can emerge as major viral population, conferring drug resistance and treatment failure. Objectives: The aim of this study was to investigate and identify prevalent mutations of RT region of hepatitis B virus genome in patients with chronic hepatitis B (CHB) untreated with antiviral drugs in South-West of Iran. Materials and Methods: A total of 45 cases with CHB who did not receive the treatment of lamivudine and any other antivirus drugs within the last one year were randomly chosen. After sample collection and HBV DNA extraction, RT region was amplified by polymerase chain reaction (PCR). Then PCR products were sequenced and HBV RT region mutations and amino acid changes were analyzed either manually or using web-based programs, on the basis of comparison of the obtained sequences with a set of HBV reference sequences. Results: A total of 23 (51.1%) mutations and amino acid changes were detected in studied 45 untreated patients. Of these, 3 (6.6%) patients had primary resistance mutation (rtM204I, rtA181T and rtA181S) and 20 (44.4%) patients had secondary resistance mutations. Conclusion: High prevalence of mutations was found in HBV RT region of untreated patients. Most of these mutations were associated with resistance to adefovir and one patient had primary resistance mutation to lamivudine. Awareness of these resistance patterns might help in the antiviral therapy and for predicting clinical outcomes. PMID:24064642

Hamidi-Fard, M; Makvandi, M; Samarbaf-Zadeh, A; Hajiani, E; Shayesteh, A; Masjedizadeh, A


Evolution of microbes and viruses: a paradigm shift in evolutionary biology?  

PubMed Central

When Charles Darwin formulated the central principles of evolutionary biology in the Origin of Species in 1859 and the architects of the Modern Synthesis integrated these principles with population genetics almost a century later, the principal if not the sole objects of evolutionary biology were multicellular eukaryotes, primarily animals and plants. Before the advent of efficient gene sequencing, all attempts to extend evolutionary studies to bacteria have been futile. Sequencing of the rRNA genes in thousands of microbes allowed the construction of the three- domain “ribosomal Tree of Life” that was widely thought to have resolved the evolutionary relationships between the cellular life forms. However, subsequent massive sequencing of numerous, complete microbial genomes revealed novel evolutionary phenomena, the most fundamental of these being: (1) pervasive horizontal gene transfer (HGT), in large part mediated by viruses and plasmids, that shapes the genomes of archaea and bacteria and call for a radical revision (if not abandonment) of the Tree of Life concept, (2) Lamarckian-type inheritance that appears to be critical for antivirus defense and other forms of adaptation in prokaryotes, and (3) evolution of evolvability, i.e., dedicated mechanisms for evolution such as vehicles for HGT and stress-induced mutagenesis systems. In the non-cellular part of the microbial world, phylogenomics and metagenomics of viruses and related selfish genetic elements revealed enormous genetic and molecular diversity and extremely high abundance of viruses that come across as the dominant biological entities on earth. Furthermore, the perennial arms race between viruses and their hosts is one of the defining factors of evolution. Thus, microbial phylogenomics adds new dimensions to the fundamental picture of evolution even as the principle of descent with modification discovered by Darwin and the laws of population genetics remain at the core of evolutionary biology.

Koonin, Eugene V.; Wolf, Yuri I.



Increase of cells expressing PD-L1 in bovine leukemia virus infection and enhancement of anti-viral immune responses in vitro via PD-L1 blockade  

PubMed Central

The inhibitory receptor programmed death-1 (PD-1) and its ligand, programmed death-ligand 1 (PD-L1) are involved in immune evasion mechanisms for several pathogens causing chronic infections. Blockade of the PD-1/PD-L1 pathway restores anti-virus immune responses, with concomitant reduction in viral load. In a previous report, we showed that, in bovine leukemia virus (BLV) infection, the expression of bovine PD-1 is closely associated with disease progression. However, the functions of bovine PD-L1 are still unknown. To investigate the role of PD-L1 in BLV infection, we identified the bovine PD-L1 gene, and examined PD-L1 expression in BLV-infected cattle in comparison with uninfected cattle. The deduced amino acid sequence of bovine PD-L1 shows high homology to the human and mouse PD-L1. The proportion of PD-L1 positive cells, especially among B cells, was upregulated in cattle with the late stage of the disease compared to cattle at the aleukemic infection stage or uninfected cattle. The proportion of PD-L1 positive cells correlated positively with prediction markers for the progression of the disease such as leukocyte number, virus load and virus titer whilst on the contrary, it inversely correlated with the degree of interferon-gamma expression. Blockade of the PD-1/PD-L1 pathway in vitro by PD-L1-specific antibody upregulated the production of interleukin-2 and interferon-gamma, and correspondingly, downregulated the BLV provirus load and the proportion of BLV-gp51 expressing cells. These data suggest that PD-L1 induces immunoinhibition in disease progressed cattle during chronic BLV infection. Therefore, PD-L1 would be a potential target for developing immunotherapies against BLV infection.



IgA Antibody Response of Swine to Foot-and-Mouth Disease Virus Infection and Vaccination? #  

PubMed Central

Foot-and-mouth disease virus (FMDV) continues to be a significant economic problem worldwide. Control of the disease involves the use of killed-virus vaccines, a control measure developed decades ago. After natural infection, the primary site of replication of FMDV is the pharyngeal area, suggesting that a mucosal immune response is the most effective. Humoral immunity to killed-virus vaccination induces antibodies that can prevent the clinical disease but not local infection. Determining whether infection or vaccination stimulates IgA-mediated local immunity depends on the method of analysis. Different assays have been described to analyze the quality of antibody responses of cattle and swine to FMDV, including indirect double-antibody sandwich enzyme-linked immunosorbent assay (IDAS-ELISA) and antibody capture assay-ELISA (ACA-ELISA). We tested these assays on swine and show that vaccinated animals had FMDV-specific IgM and IgG but no IgA in either serum or saliva. After the infection, both assays detected FMDV-specific IgM, IgG, and IgA in serum. Notably, serum IgA was more readily detected using the ACA-ELISA, whereas IgA was not detected in saliva with this assay. FMDV-specific IgA antibodies were detected in saliva samples using the IDAS-ELISA. These data show that parenterally administered, killed-virus vaccine does not induce a mucosal antibody response to FMDV and illuminates limitations and appropriate applications of the two ELISAs used to measure FMDV-specific responses. Further, the presence of the IgA antivirus in serum correlates with the presence of such antibodies in saliva.

Pacheco, Juan M.; Butler, John E.; Jew, Jessica; Ferman, Geoffrey S.; Zhu, James; Golde, William T.



Structural basis for antiviral inhibition of the main protease, 3C, from human enterovirus 93.  


Members of the Enterovirus genus of the Picornaviridae family are abundant, with common human pathogens that belong to the rhinovirus (HRV) and enterovirus (EV) species, including diverse echo-, coxsackie- and polioviruses. They cause a wide spectrum of clinical manifestations ranging from asymptomatic to severe diseases with neurological and/or cardiac manifestations. Pandemic outbreaks of EVs may be accompanied by meningitis and/or paralysis and can be fatal. However, no effective prophylaxis or antiviral treatment against most EVs is available. The EV RNA genome directs the synthesis of a single polyprotein that is autocatalytically processed into mature proteins at Gln?Gly cleavage sites by the 3C protease (3C(pro)), which has narrow, conserved substrate specificity. These cleavages are essential for virus replication, making 3C(pro) an excellent target for antivirus drug development. In this study, we report the first determination of the crystal structure of 3C(pro) from an enterovirus B, EV-93, a recently identified pathogen, alone and in complex with the anti-HRV molecules compound 1 (AG7404) and rupintrivir (AG7088) at resolutions of 1.9, 1.3, and 1.5 Å, respectively. The EV-93 3C(pro) adopts a chymotrypsin-like fold with a canonically configured oxyanion hole and a substrate binding pocket similar to that of rhino-, coxsackie- and poliovirus 3C proteases. We show that compound 1 and rupintrivir are both active against EV-93 in infected cells and inhibit the proteolytic activity of EV-93 3C(pro) in vitro. These results provide a framework for further structure-guided optimization of the tested compounds to produce antiviral drugs against a broad range of EV species. PMID:21835784

Costenaro, Lionel; Kaczmarska, Zuzanna; Arnan, Carme; Janowski, Robert; Coutard, Bruno; Solà, Maria; Gorbalenya, Alexander E; Norder, Heléne; Canard, Bruno; Coll, Miquel



Active Depletion of Host Cell Inhibitor-of-Apoptosis Proteins Triggers Apoptosis upon Baculovirus DNA Replication?  

PubMed Central

Apoptosis is an important antivirus defense by virtue of its impact on virus multiplication and pathogenesis. To define molecular mechanisms by which viruses are detected and the apoptotic response is initiated, we examined the antiviral role of host inhibitor-of-apoptosis (IAP) proteins in insect cells. We report here that the principal IAPs, DIAP1 and SfIAP, of the model insects Drosophila melanogaster and Spodoptera frugiperda, respectively, are rapidly depleted and thereby inactivated upon infection with the apoptosis-inducing baculovirus Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV). Virus-induced loss of these host IAPs triggered caspase activation and apoptotic death. Elevation of IAP levels by ectopic expression repressed caspase activation. Loss of host IAP in both species was triggered by AcMNPV DNA replication. By using selected inhibitors, we found that virus-induced IAP depletion was mediated in part by the proteasome but not by caspase cleavage. Consistent with this conclusion, mutagenic disruption of the SfIAP RING motif, which acts as an E3 ubiquitin ligase, stabilized SfIAP during infection. Importantly, SfIAP was also stabilized upon the removal of its 99-residue N-terminal leader, which serves as a critical determinant of IAP turnover. These data indicated that a host pathway initiated by virus DNA replication and acting through instability motifs embedded within IAP triggers IAP depletion and thereby causes apoptosis. Taken together, the results of our study suggest that host modulation of cellular IAP levels is a conserved mechanism by which insects mount an apoptotic antiviral response. Thus, host IAPs may function as critical sentinels of virus invasion in insects.

Vandergaast, Rianna; Schultz, Kimberly L. W.; Cerio, Rebecca J.; Friesen, Paul D.



Tamiflu-Resistant but HA-Mediated Cell-to-Cell Transmission through Apical Membranes of Cell-Associated Influenza Viruses  

PubMed Central

The infection of viruses to a neighboring cell is considered to be beneficial in terms of evasion from host anti-virus defense systems. There are two pathways for viral infection to “right next door”: one is the virus transmission through cell-cell fusion by forming syncytium without production of progeny virions, and the other is mediated by virions without virus diffusion, generally designated cell-to-cell transmission. Influenza viruses are believed to be transmitted as cell-free virus from infected cells to uninfected cells. Here, we demonstrated that influenza virus can utilize cell-to-cell transmission pathway through apical membranes, by handover of virions on the surface of an infected cell to adjacent host cells. Live cell imaging techniques showed that a recombinant influenza virus, in which the neuraminidase gene was replaced with the green fluorescence protein gene, spreads from an infected cell to adjacent cells forming infected cell clusters. This type of virus spreading requires HA activation by protease treatment. The cell-to-cell transmission was also blocked by amantadine, which inhibits the acidification of endosomes required for uncoating of influenza virus particles in endosomes, indicating that functional hemagglutinin and endosome acidification by M2 ion channel were essential for the cell-to-cell influenza virus transmission. Furthermore, in the cell-to-cell transmission of influenza virus, progeny virions could remain associated with the surface of infected cell even after budding, for the progeny virions to be passed on to adjacent uninfected cells. The evidence that cell-to-cell transmission occurs in influenza virus lead to the caution that local infection proceeds even when treated with neuraminidase inhibitors.

Nagata, Kyosuke



NK-1 receptor antagonists: a new paradigm in pharmacological therapy.  


The neuropeptide substance P (SP) shows a widespread distribution in both the central and peripheral nervous systems and it is known that after binding to the neurokinin-1 (NK-1) receptors, SP regulates many biological functions in the central nervous system such as emotional behaviour, stress, depression, anxiety, emesis, migraine, alcohol addiction and neurodegeneration. SP has been also implicated in pain, inflammation, hepatotoxicity and in virus proliferation, and it plays an important role in cancer (e.g., tumour cell proliferation, angiogenesis, and the migration of tumour cells for invasion and metastasis). By contrast, it is known that after binding to NK-1 receptors, NK-1 receptor antagonists specifically inhibit the above-mentioned biological functions mediated by SP. Thus, these antagonists exert an anxyolitic, antidepressant, antiemetic, antimigraine, antialcohol addiction or neuroprotector effect in the central nervous system, and they play a role in analgesic, antiinflammatory, hepatoprotector processes and in antivirus proliferation. Regarding cancer, NK-1 receptor antagonists exert an antitumour action (inducing tumour cell death by apoptosis), and induce antiangiogenesis and inhibit the migration of tumour cells. It is also known that NK-1 receptors have a widespread distribution and that they are overexpressed in tumour cells. Thus, NK-1 receptor antagonists are molecularly targeted agents. In general, current drugs have a single therapeutic effect, although less commonly they may exert several. However, the data reported above indicate that NK-1 receptor antagonists are promising drugs, exerting many therapeutic effects (the action of such antagonists is dose-dependent and, depending on the concentration, has more positive effects). In this review, we update the multiple therapeutic effects exerted by NK-1 receptor antagonists. PMID:21466470

Muñoz, M; Coveñas, R



The Forward Exchange Market and the Effects of Domestic and External Disturbances under Alternative Exchange Rate Systems (Le marché des changes à terme et l'incidence des perturbations intérieures et extérieures sous différents régimes de taux de change) (El mercado de divisas a plazo y los efectos de las perturbaciones internas y externas bajo distintos sistemas de tipos de cambio)  

Microsoft Academic Search

Les auteurs de la présente étude intègrent dans un modèle macro-économique d'une économie ouverte le marché des changes à terme et les anticipations des spéculateurs en ce qui concerne le futur taux de change au comptant. Ils examinent l'incidence d'un certain nombre de perturbations exogènes sur le revenu, les taux d'intérêt, les taux de change et les réserves de la

Victor Argy; Michael G. Porter



BK090082 Letter  

Center for Biologics Evaluation and Research (CBER)

... for Sistema de Gestión del Plasma or Plasma Management System) Version 7.0 is an application designed to manage the logistics of plasma ... More results from


Comunicado de la FDA sobre la seguridad de los ...  

Center for Drug Evaluation (CDER)

... debilitamiento del sistema inmunitario pueden estar la infección con el virus de inmunodeficiencia humana (VIH), la leucemia o linfoma, o tomar el ... More results from


Stress in America  


... Care Connection Health Care System Falls Short on Stress Management – Press release Sistema de salud se queda corto ... warning signs of stress Mind/body health: stress Stress management for caregivers Related Topics How stress harms your ...


Dinámica de planetas extrasolares resonantes  

NASA Astrophysics Data System (ADS)

Actualmente se han detectado 117 planetas alrededor de estrellas de Secuencia Principal, incluyendo 12 sistemas planetarios, cada uno con dos o tres miembros. De estos últimos, ocho poseen planetas en órbitas próximas y sus perturbaciones gravitacionales se convierten en un factor fundamental para la estabilidad orbital del sistema. Todos se encuentran en configuraciones resonantes, desde la conmensurabilidad de movimientos 2/1 de Gliese 876, hasta la resonancia secular de Ups And. En esta presentación analizamos varios aspectos de la dinámica resonante de los planetas extrasolares, incluyendo la existencia de soluciones de equilibrio, construcción de modelos analógicos y métodos para la determinación de masas individuales. También discutimos por qué las resonancias son tan frecuentes en estos sistemas, comparado con nuestro propio Sistema Solar. Por último, intentamos relacionar estos modelos con la hipótesis de migración planetaria, buscando límites en su extensión y en los posibles mecanismos que le dieron origen.

Beauge, C.


El cáncer según su ubicación en el cuerpo: Digestivo y gastrointestinal

In English En español In English En español Para buscar un tipo de cáncer, seleccione su ubicación en el cuerpo — Aparato locomotor Aparato respiratorio y tórax Cabeza y cuello Célula germinativa Cerebro y sistema nervioso > Digestivo y


El cáncer según su ubicación en el cuerpo: Cabeza y cuello

In English En español In English En español Para buscar un tipo de cáncer, seleccione su ubicación en el cuerpo — Aparato locomotor Aparato respiratorio y tórax > Cabeza y cuello Célula germinativa Cerebro y sistema nervioso Digestivo y


El cáncer según su ubicación en el cuerpo: Seno (mama)

In English En español In English En español Para buscar un tipo de cáncer, seleccione su ubicación en el cuerpo — Aparato locomotor Aparato respiratorio y tórax Cabeza y cuello Célula germinativa Cerebro y sistema nervioso Digestivo y gastrointestinal


El cáncer según su ubicación en el cuerpo: Aparato locomotor

In English En español In English En español Para buscar un tipo de cáncer, seleccione su ubicación en el cuerpo — > Aparato locomotor Aparato respiratorio y tórax Cabeza y cuello Célula germinativa Cerebro y sistema nervioso Digestivo y


El cáncer según su ubicación en el cuerpo: Piel

In English En español In English En español Para buscar un tipo de cáncer, seleccione su ubicación en el cuerpo — Aparato locomotor Aparato respiratorio y tórax Cabeza y cuello Célula germinativa Cerebro y sistema nervioso Digestivo y gastrointestinal


El cáncer según su ubicación en el cuerpo: Primario desconocido

In English En español In English En español Para buscar un tipo de cáncer, seleccione su ubicación en el cuerpo — Aparato locomotor Aparato respiratorio y tórax Cabeza y cuello Célula germinativa Cerebro y sistema nervioso Digestivo y gastrointestinal


El cáncer según su ubicación en el cuerpo: Riñones y aparato genitourinario

In English En español In English En español Para buscar un tipo de cáncer, seleccione su ubicación en el cuerpo — Aparato locomotor Aparato respiratorio y tórax Cabeza y cuello Célula germinativa Cerebro y sistema nervioso Digestivo y gastrointestinal


El cáncer según su ubicación en el cuerpo: Aparato respiratorio y tórax

In English En español In English En español Para buscar un tipo de cáncer, seleccione su ubicación en el cuerpo — Aparato locomotor > Aparato respiratorio y tórax Cabeza y cuello Célula germinativa Cerebro y sistema nervioso Digestivo y


El cáncer según su ubicación en el cuerpo: Célula germinativa

In English En español In English En español Para buscar un tipo de cáncer, seleccione su ubicación en el cuerpo — Aparato locomotor Aparato respiratorio y tórax Cabeza y cuello > Célula germinativa Cerebro y sistema nervioso Digestivo y


El cáncer según su ubicación en el cuerpo: Ojo

In English En español In English En español Para buscar un tipo de cáncer, seleccione su ubicación en el cuerpo — Aparato locomotor Aparato respiratorio y tórax Cabeza y cuello Célula germinativa Cerebro y sistema nervioso Digestivo y gastrointestinal


Epidemiology of Acute Viral Hepatitis: Twenty Years of Surveillance through SEIEVA in Italy and a Review of the Literature (Epidemiologia Dell'epatite Virale Acuta: Venti Anni di Sorveglianza del SEIEVA in Italia e Rassegna della Letteratura).  

National Technical Information Service (NTIS)

SEIEVA (Sistema Epidemiologico Integrato dell'Epatite Virale Acuta: Integrated Epidemiological System of Acute Viral Hepatitis) was created in 1985 at the Istituto Superiore di Sanita and started its full activity in 1986. This report is published on the ...

A. Mele M. E. Tosti E. Spada A. Mariano E. Bianco



Huracanes e inundaciones  

Center for Biologics Evaluation and Research (CBER)

... Impact of Severe Weather Conditions on Biological Products. ... eléctrica, es posible que no estén funcionando los sistemas de control de temperatura ... More results from


Mobilització de classes, corporativisme i estar de benestar al Japó  

Microsoft Academic Search

En aquest article s'analitza i s'explica la conformació de l'actual sistema de relacions industrials al Japó utilitzant el marc teòric establert per Esping-Andersen per a I'explicació dels diferents tipus d'estat de benestar. La utilització d'aquest model porta a considerar l'actual sistema de relacions industrials al Japó com el resultat de les eleccions racionals desenvolupades pels actors socials al llarg del

Lluís Valls Campà



International Liquidity and the Balance of Payments (La liquidité internationale et la balance des paiements) (La liquides internacional y la balanza de pagos)  

Microsoft Academic Search

Il existe à l'heure actuelle deux manières principales de créer des réserves internationales d'un caractère inconditionnel: 1) par le mécanisme de l'étalon de change-or, en utilisant des monnaies-clés, principalement des dollars; 2) par les positions de tranche-or au Fonds Monétaire International. Mais une troisième solution a été proposée récemment, à savoir la création d'unités de réserve collectives (C.R.U.) administrées sur

Oscar L. Altman



La pr?vention des infections par le virus respiratoire syncytial  

PubMed Central

RÉSUMÉ L’infection par le virus respiratoire syncytial (VRS) est la principale cause d’infections des voies respiratoires inférieures chez les jeunes enfants. Le palivizumab, un anticorps monoclonal anti-VRS, réduit le taux d’hospitalisation des enfants à haut risque mais est très coûteux. Le présent document de principes remplace les trois précédents documents de principes de la Société canadienne de pédiatrie sur le sujet et est mis à jour principalement pour traiter des récentes modifications aux lignes directrices de l’American Academy of Pediatrics dans le contexte canadien. Il contient une analyse des publications ainsi que des recommandations au sujet de l’utilisation du palivizumab chez les enfants à haut risque

Robinson, JL




Microsoft Academic Search

Résumé  La défécographie est un examen radiologique permettant une évaluation fonctionnelle de la partie postérieure du pelvis. Le\\u000a remplissage des cavités vaginale, rectale et iléale par un produit de contraste radiologique permet l’obtention de clichés\\u000a dynamiques de ces organes pendant une défécation. Les principales informations apportées concernent à la fois la qualité de\\u000a l’évacuation rectale et les anomalies de l’anatomie fonctionnelle

L. Siproudhis



Amélioration des propriétés d’un tuf naturel utilisé en technique routière saharienne par ajout d’un sable calcaire  

Microsoft Academic Search

Le matériau tuf constitue depuis longtemps la composante principale des couches de chaussées d’un nombre important de routes en Algérie. Une phase expérimentale préliminaire a permis de déterminer la composition optimale du mélange tuf-sable calcaire vis-à-vis de la résistance à la compression. Par la suite, des essais triaxiaux consolidés drainés sur la composition optimale sont effectués. La deuxième phase consiste

Idriss Goual; Mohamed Sayeh Goual; Saïd Taibi; Nabil Abou-Bekr



Politique monétaire en économie d'endettement vue à travaes le modèle OFCE-annuel  

Microsoft Academic Search

[fre] On présente l'estimation sur données françaises d'un modèle d'économie d'endettement dont les principales caractéristiques résultent des hypothèses suivantes. Les ménages placent l'essentiel de leur épargne sous forme monétaire. Le marché des titres est donc de petite dimension, ce qui oblige les entreprises à se financer pour l'essentiel par le crédit bancaire. Les autorités monétaires n'exercent le plus souvent aucun

Michel Boutillier; Pierre Villa



The Excellence study in Internal Public Relations, an international paradigm  

Microsoft Academic Search

L’article mostra com els indicadors de l’estudi d’Excel·lència són necessaris per tal de desenvolupar els elements clau de les relacions públiques internes i per ajudar a establir una identitat i una cultura d’organització a través d’uns valors corresponents. La implicació de l’empleat es basa principalment en la correcta administració del compromís per part de la coalició dominant amb els seus

Enric Ordeix i Rigo



Politiques de « non-prix » : Equilibre et optimum  

Microsoft Academic Search

[fre] L'objectif de ce papier est de mettre en évidence, à l'occasion d'une synthèse de la littérature, les principales causes de divergences entre profitabilité (privée) et désirabilité (sociale) d'une allocation des ressources pour les différentes structures de marché quand les producteurs déterminent non seulement le prix de leur production mais également leur niveau de qualité, le montant de la publicité

Laurent dUrsel



Le rôle des banques dans le gouvernement des entreprises allemandes. Etude à travers trois cas d'OPA hostiles  

Microsoft Academic Search

Le gouvernement d'entreprises (désormais GE) allemand a connu ces dernières années une évolution importante. S'inclinant devant les directives européennes, le Parlement a adopté des nouvelles lois visant, principalement, à améliorer le fonctionnement du marché des capitaux et à réduire l'influence des banques. Notre article consiste à étudier le rôle important des banques dans le GE allemand afin de comprendre la

Mehdi Nekhili



Le sous-emploi a doublé en quatre ans  

Microsoft Academic Search

[fre] Le sous-emploi touchait, en mars 1986, 400 000 ou 500 000 personnes selon la façon dont on le mesure. C'est un phénomène d'ampleur encore modeste, mais il a doublé depuis quatre ans. Il est principalement répandu parmi les jeunes qui viennent d'être embauchés, en particulier dans la Fonction publique (État ou collectivités territoriales) et le secteur associatif. Plus qu'un

Claude Thélot



An appraisal of the present treatment of barbiturate  

Microsoft Academic Search

\\u000a Résumé La fréquence fortement croissante des empoisonnements aux barbituriques pose un problème thérapeutique dont la documentation\\u000a est abondante ?après les statistiques faites en Grande-Bretagne, dans les pays Scandinaves et aux Etats-Unis. Aujour?hui,\\u000a ces médicaments sont devenus la principale cause de ?intoxication médicamenteuse aigue dans le monde.  Cette expansion universelle des empoisonnements aigus par les barbituriques est devenue un stimulant pour essayer

Leonard Cecil Jenkins; Horace B. Graves



Prise en charge du paludisme pédiatrique: rôle des interventions nutritionnelles  

Microsoft Academic Search

RésuméLe paludisme est la principale cause de morbidité et de mortalité chez l’enfant, particulièrement en Afrique sub-saharienne. Malgré des progrès substantiels du traitement du paludisme pédiatrique au moyen de polythérapies basées sur l’artémisinine, de nombreux obstacles s’opposent encore à la mise en œuvre efficace de ces nouvelles options thérapeutiques très efficaces. De même, des moyens efficaces sont disponibles pour la

Akato Kwame Osei; Davidson H. Hamer



L'Aventure du LHC  


Cette présentation s’adressera principalement aux personnes qui ont construit le LHC. La construction du LHC fut longue et difficile. De nombreux problèmes sont apparus en cours de route. Tous ont été résolus grâce au dévouement et à l’engagement du personnel et des collaborateurs. Je reviendrai sur les coups durs et les réussites qui ont marqués ces 15 dernières années et je vous montrerai combien cette machine, le fruit de vos efforts, est extraordinaire.


Calibrazioni a terra e prestazioni in volo di spettrometri ad immagine nel visibile e nel vicino infrarosso per l'esplorazione planetaria  

Microsoft Academic Search

Nel corso dell'ultimo decennio l'esplorazione planetaria ha potuto beneficiare dei dati prodotti dagli spettrometri ad immagine: grazie a questa nuova classe di strumenti, realizzati per l'osservazione in remoto di superfici ed atmosfere planetarie, è possibile acquisire dati iperspettrali con elevati poteri risolutivi spaziali e spettrali. Il principale vantaggio offerto dagli spettrometri ad immagine, rispetto alle camere ed agli spettrometri puntuali,

Gianrico Filacchione



Propuesta de un m‚todo para la elecci¢n de buenas alternativas para la localizaci¢n de empresas de reciclaje de RAEE en Espa¤a  

Microsoft Academic Search

Ante la necesidad de Espa¤a de instalar nuevas empresas de reciclaje de RAEE, este trabajo proporciona a los agentes decisores una ordenaci¢n de los principales municipios espa¤oles seg£n su apropiabilidad para la instalaci¢n de estas empresas. Desarrolla un procedimiento que consiste en la identificaci¢n de los factores relevantes que deben tenerse en cuenta y en la posterior aplicaci¢n de una

Dolores Queiruga; Javier Gonz lez Benito; Grit Walther; Thomas Spengler



Maisons de disques et artistes face au peer-to-peer : convergence ou con‡it d'intérêts ?  

Microsoft Academic Search

Nous proposons un modèle reproduisant les principales caractéristiques de l'industrie musicale, à l'ère du numérique : forte hétérogénéité des artistes en matière de notoriété ; co-existence des marchés de la musique enregistrée et des concerts ; apparition des réseaux P2P permettant les échanges de …chiers numériques et donc la montée en puissance du pi- ratage mais également le développement d'un

Nicolas CURIEN; François MOREAU


Nouvelles données sur la régulation de la sécrétion du glucagon par les cellules alpha des îlots pancréatiques et son importance dans le diabète  

Microsoft Academic Search

Le diabète est la principale cause de mortalité en Amérique du Nord et, au Canada uniquement, plus de 2 millions de personnes en sont atteints. L'hyperglycémie est le signe caractéristique du diabète et une cause prédominante de l'apparition de complications à long terme associées à la maladie. Dans des conditions normales, un taux accru de glucose stimule la sécrétion d'insuline



Pauvreté et fécondité en Haïti  

Microsoft Academic Search

L'objectif principal de ce papier est d'analyser la relation entre la pauvreté et la fécondité à partir des données de Enquête Démographique et de Santé (EDS) d'Haïti de 1994-1995. Pour ce faire, d'une part, la pauvreté est appréhendée principalement selon deux types d'approche : (i) l'approche axée sur le concept d'actifs essentiels comprenant, d'un côté, l'approche traditionnelle relative à l'accès

Arnousse Beaulière



Traitement pharmacologique de l’anorexie et de la cachexie chez les patients porteurs d’un cancer du tractus digestif  

Microsoft Academic Search

Résumé  L’anorexie et la cachexie surviennent fréquemment chez des patients à un stade avancé de cancer du tractus digestif. Une alimentation\\u000a réduite et une augmentation des dépenses énergétiques sont les principales causes de ce syndrome clinique. De plus, la perturbation\\u000a de plusieurs hormones de même que les cytoxines jouent un rôle étiologique majeur. Dans la plupart des cas, le traitement\\u000a des

F. Frascio; A. Giacosa



Effet établissement et salaires des diplômés des universités françaises  

Microsoft Academic Search

A la suite notamment des travaux de Card et Krueger en 1992, une abondante littérature micro-économétrique, principalement développée aux Etats-Unis, a étudié les liens entre qualité de l'éducation, mesurée par différents inputs éducatifs et salaires des diplômés ou les rendements de l'éducation. À partir de données françaises provenant de l'enquête « Génération 98 » du Céreq enrichies pour les sortants

Jean-François Giret; Mathieu Goudard



Modélisation et simulation à topologie variable des convertisseurs statiques et des entraînements électromécaniques  

NASA Astrophysics Data System (ADS)

This paper deals with the automatic modeling with changeable topology of static converters (ideal discret-time modeling of switches), mainly for their own simulation and specifically the one of electric drives. Nous proposons une approche pour synthétiser automatiquement le modèle à topologie variable des convertisseurs statiques (modèle discret idéal des semi-conducteurs), principalement en vue de leur propre simulation et notamment celle des entraînements électromécaniques.

Gerbaud, L.; Lechevalier, C.; Bolopion, A.; Bigeon, J.



La recherche de granulats en region centre  

Microsoft Academic Search

Résumé  Le lit de la Loire reste la principale ressource de granulats de la Région Centre. Pourtant, à la suite des désordres dûs\\u000a à son abaissement, la groupe consultatif interministériel présidé par Monsieur l'Ingénieur Général des Ponts & Chaussées FOUCAUD,\\u000a a conclu à la nécessité de limiter les extractions de sables et graviers dans le lit vif du fleuve.\\u000a \\u000a Pour cette

S. Chevrel; P. Maillard




Microsoft Academic Search

La presente ricerca è indirizzata all'individuazione di una possibile area di intersezione fra il curricolo della P4C e il mondo delle scienze motorie. Il percorso è tracciato sostanzialmente su due filoni. Quello principale è rivolto all'analisi della persona intesa come corpo vivente, come corpo proprio che si estrinseca attraverso movimenti caratterizzati da razionalità e intenzionalità. In particolar modo ci si

Stefano Scarpa


La réforme de la PAC de 2003 et le régime du paiement unique : impacts de différentes options de mise en œuvre au niveau français  

Microsoft Academic Search

La principale innovation de la réforme de la PAC de 2003 par rapport aux précédentes est l'introduction du régime du paiement unique. Le principe général est de briser le lien entre le soutien des revenus agricoles et l'acte de production agricole. Toutefois, cette réforme autorise certaines dérogations à ce principe général, et ce à la discrétion des Etats membres. L'objectif

Alexandre Gohin



Le transport routier de marchandises en Europe en 2005. L'Allemagne et l'Espagne, en tête du TRM européen  

Microsoft Academic Search

En 2005, se dessine une Europe du transport routier de marchandises à deux vitesses : l'une dynamique, notamment à l'international, avec les pavillons allemand, espagnol, italien, portugais, des pays baltes, polonais ; l'autre avec les pavillons français, britannique et belge, qui perdent des parts de marché et de l'activité.Les pavillons de l'Est, principalement de la Pologne et des pays baltes,

Pierre Billet-Legros; Annie Delort



Le fin mot de l'histoire: La Tempête en juin et les perspectives de Némirovsky  

Microsoft Academic Search

Le présent article analyse la voix narrative d'Irène Némirovsky dans Tempête en juin, la première partie de son œuvre posthume Suite française, publiée en 2004 après être restée inconnue pendant quelque soixante ans. Nous avançons donc deux thèses principales. D'abord, contrairement à ce qu'affirmait Sartre dans son article sur ‘M. François Mauriac et la liberté’, c'est justement un point de

Nathan Bracher