Sample records for protactinium 233 target

  1. Separation of Protactinium Employing Sulfur-Based Extraction Chromatographic Resins.

    PubMed

    Mastren, Tara; Stein, Benjamin W; Parker, T Gannon; Radchenko, Valery; Copping, Roy; Owens, Allison; Wyant, Lance E; Brugh, Mark; Kozimor, Stosh A; Nortier, F Meiring; Birnbaum, Eva R; John, Kevin D; Fassbender, Michael E

    2018-06-05

    Protactinium-230 ( t 1/2 = 17.4 d) is the parent isotope of 230 U ( t 1/2 = 20.8 d), a radionuclide of interest for targeted alpha therapy (TAT). Column chromatographic methods have been developed to separate no-carrier-added 230 Pa from proton irradiated thorium targets and accompanying fission products. Results reported within demonstrate the use of novel sulfur bearing chromatographic extraction resins for the selective separation of protactinium. The recovery yield of 230 Pa was 93 ± 4% employing a R 3 P═S type commercially available resin and 88 ± 4% employing a DGTA (diglycothioamide) containing custom synthesized extraction chromatographic resin. The radiochemical purity of the recovered 230 Pa was measured via high purity germanium γ-ray spectroscopy to be >99.5% with the remaining radioactive contaminant being 95 Nb due to its similar chemistry to protactinium. Measured equilibrium distribution coefficients for protactinium, thorium, uranium, niobium, radium, and actinium on both the R 3 P═S type and the DGTA resin in hydrochloric acid media are reported, to the best of our knowledge, for the first time.

  2. RECOVERY OF PROTACTINIUM FROM AQUEOUS SOLUTIONS

    DOEpatents

    Elson, R.E.

    1959-07-14

    The recovery of fluoride complexed protactinium from aqueous acidic solutions by solvent extraction is described. Generally the prccess of the invention com rises mixing an aqueous solution containing protactinium in a complexed form with an organic solvent which is specific for protactinium, such as diisopropyl carbinol, then decomposing the protactinium complex by adjusting the acidity of the aqueous solution to between 0-3 to 0-9 M in hydrogen ion concentration, and introducing a source of aluminum ions in sufficient quantity to establish a concentration of 0.5 to 1.2 M aluminum ion, whereupon decomposition of the protactinium fluoride complex takes place and the protactinium ion is taken up by the organic solvent phase.

  3. Separation of Protactinium Employing Sulfur-Based Extraction Chromatographic Resins

    DOE PAGES

    Mastren, Tara; Stein, Benjamin W.; Parker, T. Gannon; ...

    2018-05-14

    Protactinium-230 (t 1/2 = 17.4 d) is the parent isotope of 230U (t 1/2 = 20.8 d), a radionuclide of interest for targeted alpha therapy (TAT). Column chromatographic methods have been developed to separate no-carrier-added 230Pa from proton irradiated thorium targets and accompanying fission products. Results reported within this paper demonstrate the use of novel sulfur bearing chromatographic extraction resins for the selective separation of protactinium. The recovery yield of 230Pa was 93 ± 4% employing a R 3P=S type commercially available resin and 88 ± 4% employing a DGTA (diglycothioamide) containing custom synthesized extraction chromatographic resin. The radiochemical puritymore » of the recovered 230Pa was measured via high purity germanium γ-ray spectroscopy to be >99.5% with the remaining radioactive contaminant being 95Nb due to its similar chemistry to protactinium. Finally, measured equilibrium distribution coefficients for protactinium, thorium, uranium, niobium, radium, and actinium on both the R 3P=S type and the DGTA resin in hydrochloric acid media are reported, to the best of our knowledge, for the first time.« less

  4. Separation of Protactinium Employing Sulfur-Based Extraction Chromatographic Resins

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mastren, Tara; Stein, Benjamin W.; Parker, T. Gannon

    Protactinium-230 (t 1/2 = 17.4 d) is the parent isotope of 230U (t 1/2 = 20.8 d), a radionuclide of interest for targeted alpha therapy (TAT). Column chromatographic methods have been developed to separate no-carrier-added 230Pa from proton irradiated thorium targets and accompanying fission products. Results reported within this paper demonstrate the use of novel sulfur bearing chromatographic extraction resins for the selective separation of protactinium. The recovery yield of 230Pa was 93 ± 4% employing a R 3P=S type commercially available resin and 88 ± 4% employing a DGTA (diglycothioamide) containing custom synthesized extraction chromatographic resin. The radiochemical puritymore » of the recovered 230Pa was measured via high purity germanium γ-ray spectroscopy to be >99.5% with the remaining radioactive contaminant being 95Nb due to its similar chemistry to protactinium. Finally, measured equilibrium distribution coefficients for protactinium, thorium, uranium, niobium, radium, and actinium on both the R 3P=S type and the DGTA resin in hydrochloric acid media are reported, to the best of our knowledge, for the first time.« less

  5. SEPARATION OF PROTACTINIUM FROM CONTAMINANTS

    DOEpatents

    Malm, J.G.; Fried, S.

    1959-07-01

    The separation of protactinium by volatilization method is described. According to the invention, neutron irradiated finely divided thorium is reacted with aluminum trichloride or a mixture of aluminum trichloride and chlorine gas at a temperature of preferably between about 200 and 400 deg C. Following the chlorinating step the protactinium chloride along with aluminum chloride is selectively distilled from the mixture at a temperature of approximately 100 deg C. The protactinium chloride may be recovered from the mixture by treatment with sodium hydroxide, which converts the aluminum chloride to a soluble salt and forms insoluble protactinium hydroxide.

  6. PRECIPITATION OF PROTACTINIUM

    DOEpatents

    Moore, R.L.

    1958-07-15

    An lmprovement in the separation of protactinium from aqueous nitric acid solutions is described. 1t covers the use of lead dioxide and tin dioxide as carrier precipitates for the protactinium. In carrying out the process, divalent lead or divalent tin is addcd to the solution and oxidized, causing formation of a carrier precipitate of lead dioxide or stannic oxide, respectively.

  7. SEPARATION PROCESS FOR PROTACTINIUM AND COMPOUNDS THEREOF

    DOEpatents

    Van Winkle, A.

    1959-07-21

    The separation of protactinium from aqueous solutions from its mixtures with thorium, uranium and fission products is described. The process for the separation comprises preparing an ion nitric acid solution containing protactinium in the pentavalent state and contacting the solution with a fluorinated beta diketone, such as trifluoroacetylacetone, either alone or as an organic solvent solution to form a pentavalent protactinium chelate compound. When the organic solvent is present the chelate compound is extracted; otherwise it is separated by filtration.

  8. Recovery of protactinium from molten fluoride nuclear fuel compositions

    DOEpatents

    Baes, C.F. Jr.; Bamberger, C.; Ross, R.G.

    1973-12-25

    A method is provided for separating protactinium from a molten fluonlde salt composition consisting essentially of at least one alkali and alkaline earth metal fluoride and at least one soluble fluoride of uranium or thorium which comprises oxidizing the protactinium in said composition to the + 5 oxidation state and contacting said composition with an oxide selected from the group consisting of an alkali metal oxide, an alkaline earth oxide, thorium oxide, and uranium oxide, and thereafter isolating the resultant insoluble protactinium oxide product from said composition. (Official Gazette)

  9. CATION EXCHANGE METHOD FOR THE RECOVERY OF PROTACTINIUM

    DOEpatents

    Studier, M.H.; Sullivan, J.C.

    1959-07-14

    A cation exchange prccess is described for separating protactinium values from thorium values whereby they are initially adsorbed together from an aqueous 0.1 to 2 N hydrochloric acid on a cation exchange resin in a column. Then selectively eluting the thorium by an ammonium sulfate solution and subsequently eluting the protactinium by an oxalate solution.

  10. SEPARATION OF URANIUM FROM THORIUM AND PROTACTINIUM

    DOEpatents

    Musgrave, W.K.R.

    1959-06-30

    This patent relates to the separation of uranium from thorium and protactinium; such mixtures of elements usually being obtained by neutron irradiation of thorium. The method of separating the constituents has been first to dissolve the mixture of elements in concertrated nitric acid and then to remove the protactinium by absorption on manganese dioxide and the uranium by solvent extraction with ether. Prior to now, comparatively large amounts of thorium were extracted with the uranium. According to the invention this is completely prevented by adding sodium diethyldithiocarbamate to the mixture of soluble nitrate salts. The organic salt has the effect of reacting only with the uranyl nitrate to form the corresponding uranyl salt which can then be selectively extracted from the mixture with amyl acetate.

  11. SOLVENT EXTRACTION PROCESS FOR PROTACTINIUM

    DOEpatents

    Hyde, E.K.; Katzin, L.I.; Wolf, M.J.

    1961-04-01

    A process is described for separating protactinium from thorium present together as the nitrates in a 0.1 to 10 N nitric acid solution. The separation is carried out by extraction with an aliphatic alcohol, ketone, and/or ester having at least six carbon atoms, such as n-amyl acetate, 2-ethyl hexanol, and diisopropyl ketone.

  12. PROCESS FOR CONTINUOUSLY SEPARATING IRRADIATION PRODUCTS OF THORIUM

    DOEpatents

    Hatch, L.P.; Miles, F.T.; Sheehan, T.V.; Wiswall, R.H.; Heus, R.J.

    1959-07-01

    A method is presented for separating uranium-233 and protactinium from thorium-232 containing compositions which comprises irradiating finely divided particles of said thorium with a neutron flux to form uranium-233 and protactinium, heating the neutron-irradiated composition in a fluorine and hydrogen atmosphere to form volatile fluorides of uranium and protactinium and thereafter separating said volatile fluorides from the thorium.

  13. Separation of protactinum, actinium, and other radionuclides from proton irradiated thorium target

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fassbender, Michael E.; Radchenko, Valery

    Protactinium, actinium, radium, radiolanthanides and other radionuclide fission products were separated and recovered from a proton-irradiated thorium target. The target was dissolved in concentrated HCl, which formed anionic complexes of protactinium but not with thorium, actinium, radium, or radiolanthanides. Protactinium was separated from soluble thorium by loading a concentrated HCl solution of the target onto a column of strongly basic anion exchanger resin and eluting with concentrated HCl. Actinium, radium and radiolanthanides elute with thorium. The protactinium that is retained on the column, along with other radionuclides, is eluted may subsequently treated to remove radionuclide impurities to afford a fractionmore » of substantially pure protactinium. The eluate with the soluble thorium, actinium, radium and radiolanthanides may be subjected to treatment with citric acid to form anionic thorium, loaded onto a cationic exchanger resin, and eluted. Actinium, radium and radiolanthanides that are retained can be subjected to extraction chromatography to separate the actinium from the radium and from the radio lanthanides.« less

  14. RECOVERY OF PROTACTINIUM

    DOEpatents

    Kraus, K.A.; Moore, G.E.

    1959-02-01

    A process is presented for the separation of protactinium values from an aqueous solution containing Pa and Th values comprising establishing in the solution a HCl concentration of from 4 to 11 molar, contacting the resulting solution with an anion-exchange adsorbent, such as a polystyrene divinyl benzene polymer with quatenary amines as the active exchange group, to effect the adsorption of Pa values upon the adsorbent while leaving Th values in the solution, and then washlng the separated Pa bearing adsorbent with an aqueous solution of HCl of less than 4M to exclusively elute Pa values from the adsorbent. If hexavalent U values are contained in the original solution thcy are adsorbed on the resin together with Pa. A separation is offected chromatographically by percolating the resin with aqueous HCl.

  15. SEPARATION OF PROTACTINIUM FROM MOLTEN SALT REACTOR FUEL COMPOSITIONS

    DOEpatents

    Shaffer, J.H.; Strain, J.E.; Cuneo, D.R.; Kelly, M.J.

    1963-11-12

    A method for selectively precipitating protactinium from a neutron- irradiated fused fluoride salt composition comprising at least one metal fluoride selected from the group consisting of an alkali metal fluoride and an alkaline earth metal fluoride containing dissolved thorium-232 values is presented. An inorganic metal oxide corresponding to any of the metal fluorides of the composition is also added. (AEC)

  16. PROCEEDINGS OF THE PROTACTINIUM CHEMISTRY SYMPOSIUM, GATLINBURG, TENNESSEE, APRIL 25-26, 1963

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1963-04-26

    Eleven papers are presented on the chemistry of protactinium. Most of the emphasis is on solvent extraction and solution chemistry. Separate abstracts were prepared for ten of the papers; the remaining paper was previously abstracted in NSA. (D.L.C.)

  17. SEPARATION OF POLONIUM, PROTACTINIUM OR MIXTURES THEREOF IN AQUEOUS SOLUTION FROM BISMUTH, LEAD, ZIRCONIUM AND/OR COLUMBIUM VALUES

    DOEpatents

    Van Winkle, Q.; Kraus, K.A.

    1959-10-27

    A process is presented for separating polonium, protactinium, or mixtures thereof in aqueous solution from bismuth, zirconium, lead, and niobium values contained in the solution. The method comprises providing hydrochloric acid in the solution in a concentration of at least 5N. contacting the aqueous solution with a substantially waterimmiscible organic solvent such as diisopropyl ketone, and separating the aqueous phase containing the bismuth, zirconium, lead, and niobium from the organic extract phase containing the polonium, protactinium, or mixture thereof.

  18. WET FLUORIDE SEPARATION METHOD

    DOEpatents

    Seaborg, G.T.; Gofman, J.W.; Stoughton, R.W.

    1958-11-25

    The separation of U/sup 233/ from thorium, protactinium, and fission products present in neutron-irradiated thorium is accomplished by dissolving the irradiated materials in aqueous nitric acid, adding either a soluble fluoride, iodate, phosphate, or oxalate to precipltate the thorium, separating the precipltate from the solution, and then precipitating uranlum and protactinium by alkalizing the solution. The uranium and protactinium precipitate is removcd from the solution and dissolved in nitric acid. The uranyl nitrate may then be extracted from the acid solution by means of ether, and the protactinium recovered from the aqueous phase.

  19. MANGANESE DIOXIDE METHOD FOR PREPARATION OF PROTACTINIUM

    DOEpatents

    Katzin, L.I.

    1958-08-12

    A method of obtaining U/sup 233/ is described. An aqueous solution of neutriln irradiated thoriunn is treated by forming tberein a precipitate of manganese dioxide which carries and thus separates the Pa/sup 233/ from the solution. The carrier precipitate so formed is then dissolved in an acidic solution containing a reducing agent sufficiently electronegative to reduce the tetravalent manganese to the divalent state. Further purification of the Pa/sup 233/ may be obtained by forming another manganese dioxide carrier precipitate and subsequently dissolving it. Ater a sufficient number of such cycles have brought the Pa/sup 233/ to the desired purity, the solution is aged, allowing the formation ot U/sup 233/ by radioaetive decay. A manganese dioxide precipitate is then formed in the U/sup 233/ containing solution. This precipitate carries down any remaining Pa/sup 233/ thus leaving the separated U/sup 233/solution, from whieh it may be easily recovered.

  20. Method of increasing the deterrent to proliferation of nuclear fuels

    DOEpatents

    Rampolla, Donald S.

    1982-01-01

    A process of recycling protactinium-231 to enhance the utilization of radioactively hot uranium-232 in nuclear fuel for the purpose of making both fresh and spent fuel more resistant to proliferation. The uranium-232 may be obtained by the irradiation of protactinium-231 which is normally found in the spent fuel rods of a thorium base nuclear reactor. The production of protactinium-231 and uranium-232 would be made possible by the use of the thorium uranium-233 fuel cycle in power reactors.

  1. Isolation and purification of protactinium-231.

    PubMed

    Jerome, S M; Collins, S M; Happel, S; Ivanov, P; Russell, B C

    2018-04-01

    Protactinium-231 is one of the lesser known actinides, yet the measurement of this radionuclide is central to dating studies in both paleoclimate and nuclear forensics measurements; furthermore, it is important as the immediate parent nuclide of the 227 Ac decay chain. In this paper, we present the preparatory work for an upcoming CCRI(II) supplementary comparison of this radionuclide. The material used in this work was of poorly known provenance, and it was necessary to carry out a chemical purification of this material prior to use. A new extraction chromatography resin, TK 400, which has been developed for the separation of 231 Pa, was tested at NPL. The aims of the work were achieved; the recovery of 231 Pa was ~85%, the decay products were recovered in good yield (~95%) and stable element impurities were removed. Copyright © 2017. Published by Elsevier Ltd.

  2. First principles LDA + U and GGA + U study of protactinium and protactinium oxides: dependence on the effective U parameter

    NASA Astrophysics Data System (ADS)

    Obodo, K. O.; Chetty, N.

    2013-04-01

    The electronic structure and properties of protactinium and its oxides (PaO and PaO2) have been studied within the framework of the local density approximation (LDA), the Perdew-Burke-Ernzerhof generalized gradient approximation [GGA(PBE)], LDA + U and GGA(PBE) + U implementations of density functional theory. The dependence of selected observables of these materials on the effective U parameter has been investigated in detail. The examined properties include lattice constants, bulk moduli, the effect of charge density distributions, the hybridization of the 5f orbital and the energy of formation for PaO and PaO2. The LDA gives better agreement with experiment for the bulk modulus than the GGA for Pa but the GGA gives better structural properties. We found that PaO is metallic and PaO2 is a Mott-Hubbard insulator. This is consistent with observations for the other actinide oxides. We discover that GGA and LDA incorrectly give metallic behavior for PaO2. The GGA(PBE) + U calculated indirect band gap of 3.48 eV reported for PaO2 is a prediction and should stimulate further studies of this material.

  3. Protactinium and the intersection of actinide and transition metal chemistry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wilson, Richard E.; De Sio, Stephanie; Vallet, Valérie

    The role of the 5f and 6d orbitals in the chemistry of the actinide elements has been of considerable interest since their discovery and synthesis. Relativistic effects cause the energetics of the 5f and 6d orbitals to change as the actinide series is traversed left to right imparting a rich and complex chemistry. The 5f and 6d atomic states cross in energy at protactinium (Pa), making it a potential intersection between transition metal and actinide chemistries. Herein, we report the synthesis of a Pa-peroxo cluster, A(6)(Pa4O(O-2)(6)F-12) [A = Rb, Cs, (CH3)(4)N], formed in pursuit of an actinide polyoxometalate. Quantum chemicalmore » calculations at the density functional theory level demonstrate equal 5f and 6d orbital participation in the chemistry of Pa and increasing 5f orbital participation for the heavier actinides. Periodic changes in orbital character to the bonding in the early actinides highlights the influence of the 5f orbitals in their reactivity and chemical structure.« less

  4. 14 CFR 16.233 - Record.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... PRACTICE FOR FEDERALLY-ASSISTED AIRPORT ENFORCEMENT PROCEEDINGS Hearings § 16.233 Record. (a) Exclusive record. The transcript of all testimony in the hearing, all exhibits received into evidence, all motions... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Record. 16.233 Section 16.233 Aeronautics...

  5. 12 CFR 233.4 - Exemptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Exemptions. 233.4 Section 233.4 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.4 Exemptions. (a) Automated...

  6. 12 CFR 233.4 - Exemptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 4 2012-01-01 2012-01-01 false Exemptions. 233.4 Section 233.4 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.4 Exemptions. (a) Automated...

  7. 12 CFR 233.4 - Exemptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 4 2013-01-01 2013-01-01 false Exemptions. 233.4 Section 233.4 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.4 Exemptions. (a) Automated...

  8. 14 CFR 16.233 - Record.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Record. 16.233 Section 16.233 Aeronautics... PRACTICE FOR FEDERALLY-ASSISTED AIRPORT ENFORCEMENT PROCEEDINGS Hearings § 16.233 Record. (a) Exclusive record. The transcript of all testimony in the hearing, all exhibits received into evidence, all motions...

  9. 14 CFR 16.233 - Record.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Record. 16.233 Section 16.233 Aeronautics... PRACTICE FOR FEDERALLY-ASSISTED AIRPORT ENFORCEMENT PROCEEDINGS Hearings § 16.233 Record. (a) Exclusive record. The transcript of all testimony in the hearing, all exhibits received into evidence, all motions...

  10. 22 CFR 233.14 - Arbitration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Arbitration. 233.14 Section 233.14 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113-6-STANDARD TERMS AND CONDITIONS § 233.14...

  11. 12 CFR 233.4 - Exemptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Exemptions. 233.4 Section 233.4 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.4 Exemptions. (a) Automated clearing house...

  12. 12 CFR 233.4 - Exemptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Exemptions. 233.4 Section 233.4 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.4 Exemptions. (a) Automated clearing house...

  13. 22 CFR 23.3 - Refunds.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Refunds. 23.3 Section 23.3 Foreign Relations DEPARTMENT OF STATE FEES AND FUNDS FINANCE AND ACCOUNTING § 23.3 Refunds. (a) Rectifications and readjustments. See § 22.6 of this chapter for outline of circumstances under which fees which have been...

  14. 49 CFR 233.9 - Reports.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Reports. 233.9 Section 233.9 Transportation Other... TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.9 Reports. Not later than April 1, 1997 and every 5 years thereafter, each carrier shall file with FRA a signal system status report “Signal System Five...

  15. 49 CFR 233.9 - Reports.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Reports. 233.9 Section 233.9 Transportation Other... TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.9 Reports. Not later than April 1, 1997 and every 5 years thereafter, each carrier shall file with FRA a signal system status report “Signal System Five...

  16. 49 CFR 233.9 - Reports.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Reports. 233.9 Section 233.9 Transportation Other... TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.9 Reports. Not later than April 1, 1997 and every 5 years thereafter, each carrier shall file with FRA a signal system status report “Signal System Five...

  17. 45 CFR 233.39 - Age.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 2 2014-10-01 2012-10-01 true Age. 233.39 Section 233.39 Public Welfare... FINANCIAL ASSISTANCE PROGRAMS § 233.39 Age. (a) Condition for plan approval. A State plan under title I or XVI of the Social Security Act may not impose any age requirement of more than 65 years. (b) Federal...

  18. 45 CFR 233.39 - Age.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false Age. 233.39 Section 233.39 Public Welfare... FINANCIAL ASSISTANCE PROGRAMS § 233.39 Age. (a) Condition for plan approval. A State plan under title I or XVI of the Social Security Act may not impose any age requirement of more than 65 years. (b) Federal...

  19. 45 CFR 233.39 - Age.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Age. 233.39 Section 233.39 Public Welfare... FINANCIAL ASSISTANCE PROGRAMS § 233.39 Age. (a) Condition for plan approval. A State plan under title I or XVI of the Social Security Act may not impose any age requirement of more than 65 years. (b) Federal...

  20. 45 CFR 233.39 - Age.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 2 2012-10-01 2012-10-01 false Age. 233.39 Section 233.39 Public Welfare... FINANCIAL ASSISTANCE PROGRAMS § 233.39 Age. (a) Condition for plan approval. A State plan under title I or XVI of the Social Security Act may not impose any age requirement of more than 65 years. (b) Federal...

  1. 12 CFR 233.7 - Regulatory enforcement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 4 2013-01-01 2013-01-01 false Regulatory enforcement. 233.7 Section 233.7 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.7 Regulatory...

  2. 12 CFR 233.7 - Regulatory enforcement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 4 2012-01-01 2012-01-01 false Regulatory enforcement. 233.7 Section 233.7 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.7 Regulatory...

  3. 12 CFR 233.7 - Regulatory enforcement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Regulatory enforcement. 233.7 Section 233.7 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.7 Regulatory...

  4. 33 CFR 117.233 - Broad Creek.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Broad Creek. 117.233 Section 117.233 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Delaware § 117.233 Broad Creek. (a) The draw of the Conrail...

  5. 33 CFR 117.233 - Broad Creek.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Broad Creek. 117.233 Section 117.233 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Delaware § 117.233 Broad Creek. (a) The draw of the Conrail...

  6. 33 CFR 117.233 - Broad Creek.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Broad Creek. 117.233 Section 117.233 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Delaware § 117.233 Broad Creek. (a) The draw of the Conrail...

  7. 33 CFR 117.233 - Broad Creek.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Broad Creek. 117.233 Section 117.233 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Delaware § 117.233 Broad Creek. (a) The draw of the Conrail...

  8. 33 CFR 117.233 - Broad Creek.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Broad Creek. 117.233 Section 117.233 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Delaware § 117.233 Broad Creek. (a) The draw of the Conrail...

  9. 14 CFR 23.3 - Airplane categories.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Airplane categories. 23.3 Section 23.3... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES General § 23.3 Airplane categories. (a) The normal category is limited to airplanes that have a seating configuration, excluding pilot...

  10. 7 CFR 58.233 - Skim milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Skim milk. 58.233 Section 58.233 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Materials § 58.233 Skim milk. The skim milk shall be separated from whole milk meeting the requirements as...

  11. 7 CFR 58.233 - Skim milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Skim milk. 58.233 Section 58.233 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Materials § 58.233 Skim milk. The skim milk shall be separated from whole milk meeting the requirements as...

  12. 14 CFR 23.3 - Airplane categories.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Airplane categories. 23.3 Section 23.3... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES General § 23.3 Airplane categories. (a) The normal category is limited to airplanes that have a seating configuration, excluding pilot...

  13. 14 CFR 23.3 - Airplane categories.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Airplane categories. 23.3 Section 23.3... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES General § 23.3 Airplane categories. (a) The normal category is limited to airplanes that have a seating configuration, excluding pilot...

  14. 14 CFR 23.3 - Airplane categories.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Airplane categories. 23.3 Section 23.3... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES General § 23.3 Airplane categories. (a) The normal category is limited to airplanes that have a seating configuration, excluding pilot...

  15. 14 CFR 23.3 - Airplane categories.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Airplane categories. 23.3 Section 23.3... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES General § 23.3 Airplane categories... airplanes that have a seating configuration, excluding pilot seats, of nine or less, a maximum certificated...

  16. 7 CFR 58.233 - Skim milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Skim milk. 58.233 Section 58.233 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Materials § 58.233 Skim milk. The skim milk shall be separated from whole milk meeting the requirements as...

  17. 7 CFR 58.233 - Skim milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Skim milk. 58.233 Section 58.233 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Materials § 58.233 Skim milk. The skim milk shall be separated from whole milk meeting the requirements as...

  18. 7 CFR 58.233 - Skim milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Skim milk. 58.233 Section 58.233 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Materials § 58.233 Skim milk. The skim milk shall be separated from whole milk meeting the requirements as...

  19. 12 CFR 233.7 - Regulatory enforcement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Regulatory enforcement. 233.7 Section 233.7 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.7 Regulatory enforcement. The...

  20. 12 CFR 233.7 - Regulatory enforcement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Regulatory enforcement. 233.7 Section 233.7 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.7 Regulatory enforcement. The...

  1. 22 CFR 233.03 - The Guarantee.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false The Guarantee. 233.03 Section 233.03 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113-6-STANDARD TERMS AND CONDITIONS § 233.03...

  2. 22 CFR 233.16 - Governing law.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Governing law. 233.16 Section 233.16 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113-6-STANDARD TERMS AND CONDITIONS § 233.16...

  3. 49 CFR 233.11 - Civil penalties.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Civil penalties. 233.11 Section 233.11..., DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.11 Civil penalties. Any person (an... subject to a civil penalty of at least $650 and not more than $25,000 per violation, except that...

  4. 49 CFR 233.11 - Civil penalties.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Civil penalties. 233.11 Section 233.11..., DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.11 Civil penalties. Any person (an... subject to a civil penalty of at least $650 and not more than $25,000 per violation, except that...

  5. 49 CFR 233.11 - Civil penalties.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Civil penalties. 233.11 Section 233.11..., DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.11 Civil penalties. Any person (an... subject to a civil penalty of at least $650 and not more than $25,000 per violation, except that...

  6. 49 CFR 233.11 - Civil penalties.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Civil penalties. 233.11 Section 233.11..., DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.11 Civil penalties. Any person (an... subject to a civil penalty of at least $650 and not more than $25,000 per violation, except that...

  7. 49 CFR 233.11 - Civil penalties.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Civil penalties. 233.11 Section 233.11..., DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.11 Civil penalties. Any person (an... subject to a civil penalty of at least $650 and not more than $25,000 per violation, except that...

  8. 40 CFR 233.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., the District of Columbia, Guam, the Commonwealth of Puerto Rico, the Virgin Islands, American Samoa... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Definitions. 233.2 Section 233.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM...

  9. 40 CFR 233.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., the District of Columbia, Guam, the Commonwealth of Puerto Rico, the Virgin Islands, American Samoa... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Definitions. 233.2 Section 233.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM...

  10. 40 CFR 233.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., the District of Columbia, Guam, the Commonwealth of Puerto Rico, the Virgin Islands, American Samoa... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Definitions. 233.2 Section 233.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM...

  11. 40 CFR 233.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., the District of Columbia, Guam, the Commonwealth of Puerto Rico, the Virgin Islands, American Samoa... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Definitions. 233.2 Section 233.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM...

  12. 40 CFR 233.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., the District of Columbia, Guam, the Commonwealth of Puerto Rico, the Virgin Islands, American Samoa... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Definitions. 233.2 Section 233.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM...

  13. 33 CFR 136.233 - Proof.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Proof. 136.233 Section 136.233 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS PROCEDURES; DESIGNATION OF...

  14. 33 CFR 136.233 - Proof.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Proof. 136.233 Section 136.233 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS PROCEDURES; DESIGNATION OF...

  15. 33 CFR 136.233 - Proof.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Proof. 136.233 Section 136.233 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS PROCEDURES; DESIGNATION OF...

  16. 33 CFR 136.233 - Proof.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Proof. 136.233 Section 136.233 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS PROCEDURES; DESIGNATION OF...

  17. 33 CFR 136.233 - Proof.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Proof. 136.233 Section 136.233 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS PROCEDURES; DESIGNATION OF...

  18. 45 CFR 233.80 - Disability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Disability. 233.80 Section 233.80 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR... in light of his impairment; an individual's disability would usually be tested in relation to ability...

  19. 22 CFR 233.02 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113-6-STANDARD TERMS AND CONDITIONS § 233.02... 233 and the State, Foreign Operations, and Related Programs Appropriations Act of 2012 (Pub. L. 112-74...

  20. 32 CFR 233.2 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... when it is a Service in the Department of Homeland Security by agreement with that Department), the... 32 National Defense 2 2014-07-01 2014-07-01 false Applicability. 233.2 Section 233.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS...

  1. 25 CFR 23.3 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Policy. 23.3 Section 23.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES INDIAN CHILD WELFARE ACT Purpose, Definitions, and... unique values of Indian culture and promote the stability and security of Indian children, Indian...

  2. 40 CFR 233.4 - Conflict of interest.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Conflict of interest. 233.4 Section 233.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM REGULATIONS General § 233.4 Conflict of interest. Any public officer or employee who has a direct...

  3. 12 CFR 233.3 - Designated payment systems.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 4 2013-01-01 2013-01-01 false Designated payment systems. 233.3 Section 233.3 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.3 Designated payment...

  4. 12 CFR 233.3 - Designated payment systems.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Designated payment systems. 233.3 Section 233.3 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.3 Designated payment...

  5. 12 CFR 233.3 - Designated payment systems.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 4 2012-01-01 2012-01-01 false Designated payment systems. 233.3 Section 233.3 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.3 Designated payment...

  6. 12 CFR 233.3 - Designated payment systems.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Designated payment systems. 233.3 Section 233.3 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.3 Designated payment systems. The...

  7. 12 CFR 233.3 - Designated payment systems.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Designated payment systems. 233.3 Section 233.3 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.3 Designated payment systems. The...

  8. 40 CFR 233.70 - Michigan.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... in Michigan 1983 Natural Resources Law. (3) The Goemaere-Anderson Wetland Protection Act, MCL 281.701..., MCLA 15.231 et seq. (3) Open Meetings Act, MCLA 15.261 et seq. (4) Michigan Environmental Protection... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Michigan. 233.70 Section 233.70...

  9. 40 CFR 233.70 - Michigan.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... in Michigan 1983 Natural Resources Law. (3) The Goemaere-Anderson Wetland Protection Act, MCL 281.701..., MCLA 15.231 et seq. (3) Open Meetings Act, MCLA 15.261 et seq. (4) Michigan Environmental Protection... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Michigan. 233.70 Section 233.70...

  10. 40 CFR 233.70 - Michigan.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... in Michigan 1983 Natural Resources Law. (3) The Goemaere-Anderson Wetland Protection Act, MCL 281.701..., MCLA 15.231 et seq. (3) Open Meetings Act, MCLA 15.261 et seq. (4) Michigan Environmental Protection... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Michigan. 233.70 Section 233.70...

  11. 40 CFR 233.70 - Michigan.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... in Michigan 1983 Natural Resources Law. (3) The Goemaere-Anderson Wetland Protection Act, MCL 281.701..., MCLA 15.231 et seq. (3) Open Meetings Act, MCLA 15.261 et seq. (4) Michigan Environmental Protection... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Michigan. 233.70 Section 233.70...

  12. 40 CFR 233.70 - Michigan.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... in Michigan 1983 Natural Resources Law. (3) The Goemaere-Anderson Wetland Protection Act, MCL 281.701..., MCLA 15.231 et seq. (3) Open Meetings Act, MCLA 15.261 et seq. (4) Michigan Environmental Protection... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Michigan. 233.70 Section 233.70...

  13. 10 CFR 600.233 - Supplies.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... supplies exceeding $5,000 in total aggregate fair market value upon termination or completion of the award... 10 Energy 4 2010-01-01 2010-01-01 false Supplies. 600.233 Section 600.233 Energy DEPARTMENT OF... Supplies. (a) Title. Title to supplies acquired under a grant or subgrant will vest, upon acquisition, in...

  14. 49 CFR 233.7 - Signal failure reports.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Signal failure reports. 233.7 Section 233.7..., DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.7 Signal failure reports. Each... other condition hazardous to the movement of a train. Form FRA F6180-14, “Signal Failure Report,” shall...

  15. 49 CFR 233.7 - Signal failure reports.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Signal failure reports. 233.7 Section 233.7..., DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.7 Signal failure reports. Each... other condition hazardous to the movement of a train. Form FRA F6180-14, “Signal Failure Report,” shall...

  16. 49 CFR 233.7 - Signal failure reports.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Signal failure reports. 233.7 Section 233.7..., DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.7 Signal failure reports. Each... other condition hazardous to the movement of a train. Form FRA F6180-14, “Signal Failure Report,” shall...

  17. 49 CFR 233.7 - Signal failure reports.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Signal failure reports. 233.7 Section 233.7..., DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.7 Signal failure reports. Each... other condition hazardous to the movement of a train. Form FRA F6180-14, “Signal Failure Report,” shall...

  18. 49 CFR 233.7 - Signal failure reports.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Signal failure reports. 233.7 Section 233.7..., DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.7 Signal failure reports. Each... other condition hazardous to the movement of a train. Form FRA F6180-14, “Signal Failure Report,” shall...

  19. 40 CFR 233.11 - Program description.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Program description. 233.11 Section 233.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE... moving mining equipment. ...

  20. 40 CFR 233.11 - Program description.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Program description. 233.11 Section 233.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE... moving mining equipment. ...

  1. 40 CFR 233.11 - Program description.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Program description. 233.11 Section 233.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE... moving mining equipment. ...

  2. 40 CFR 233.11 - Program description.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Program description. 233.11 Section 233.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE... moving mining equipment. ...

  3. 40 CFR 233.11 - Program description.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Program description. 233.11 Section 233.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE... moving mining equipment. ...

  4. 16 CFR 233.1 - Former price comparisons.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Former price comparisons. 233.1 Section 233... DECEPTIVE PRICING § 233.1 Former price comparisons. (a) One of the most commonly used forms of bargain advertising is to offer a reduction from the advertiser's own former price for an article. If the former price...

  5. 45 CFR 233.52 - Overpayment to aliens.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 2 2014-10-01 2012-10-01 true Overpayment to aliens. 233.52 Section 233.52 Public... ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.52 Overpayment to aliens. A State Plan under title IV-A of the Social Security Act, shall provide that: (a) Any sponsor of an alien and the alien shall be...

  6. 45 CFR 233.52 - Overpayment to aliens.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Overpayment to aliens. 233.52 Section 233.52 Public... ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.52 Overpayment to aliens. A State Plan under title IV-A of the Social Security Act, shall provide that: (a) Any sponsor of an alien and the alien shall be...

  7. 45 CFR 233.52 - Overpayment to aliens.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 2 2012-10-01 2012-10-01 false Overpayment to aliens. 233.52 Section 233.52... ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.52 Overpayment to aliens. A State Plan under title IV-A of the Social Security Act, shall provide that: (a) Any sponsor of an alien and the alien shall be...

  8. 45 CFR 233.52 - Overpayment to aliens.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Overpayment to aliens. 233.52 Section 233.52... ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.52 Overpayment to aliens. A State Plan under title IV-A of the Social Security Act, shall provide that: (a) Any sponsor of an alien and the alien shall be...

  9. 45 CFR 233.52 - Overpayment to aliens.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false Overpayment to aliens. 233.52 Section 233.52... ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.52 Overpayment to aliens. A State Plan under title IV-A of the Social Security Act, shall provide that: (a) Any sponsor of an alien and the alien shall be...

  10. IL233, A Novel IL-2 and IL-33 Hybrid Cytokine, Ameliorates Renal Injury.

    PubMed

    Stremska, Marta E; Jose, Sheethal; Sabapathy, Vikram; Huang, Liping; Bajwa, Amandeep; Kinsey, Gilbert R; Sharma, Poonam R; Mohammad, Saleh; Rosin, Diane L; Okusa, Mark D; Sharma, Rahul

    2017-09-01

    CD4 + Foxp3 + regulatory T cells (Tregs) protect the kidney during AKI. We previously found that IL-2, which is critical for Treg homeostasis, upregulates the IL-33 receptor (ST2) on CD4 + T cells, thus we hypothesized that IL-2 and IL-33 cooperate to enhance Treg function. We found that a major subset of Tregs in mice express ST2, and coinjection of IL-2 and IL-33 increased the number of Tregs in lymphoid organs and protected mice from ischemia-reperfusion injury (IRI) more efficiently than either cytokine alone. Accordingly, we generated a novel hybrid cytokine (IL233) bearing the activities of IL-2 and IL-33 for efficient targeting to Tregs. IL233 treatment increased the number of Tregs in blood and spleen and prevented IRI more efficiently than a mixture of IL-2 and IL-33. Injection of IL233 also increased the numbers of Tregs in renal compartments. Moreover, IL233-treated mice had fewer splenic Tregs and more Tregs in kidneys after IRI. In vitro , splenic Tregs from IL233-treated mice suppressed CD4 + T cell proliferation better than Tregs from saline-treated controls. IL233 treatment also improved the ability of isolated Tregs to inhibit IRI in adoptive transfer experiments and protected mice from cisplatin- and doxorubicin-induced nephrotoxic injury. Finally, treatment with IL233 increased the proportion of ST2-bearing innate lymphoid cells (ILC2) in blood and kidneys, and adoptive transfer of ILC2 also protected mice from IRI. Thus, the novel IL233 hybrid cytokine, which utilizes the cooperation of IL-2 and IL-33 to enhance Treg- and ILC2-mediated protection from AKI, bears strong therapeutic potential. Copyright © 2017 by the American Society of Nephrology.

  11. 48 CFR 233.215 - Contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Section 233.215 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 233... acquisition is for— (i) Aircraft (ii) Spacecraft and launch vehicles (iii) Naval vessels (iv) Missile systems...

  12. 48 CFR 233.215 - Contract clause.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Section 233.215 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 233... acquisition is for— (i) Aircraft (ii) Spacecraft and launch vehicles (iii) Naval vessels (iv) Missile systems...

  13. 48 CFR 233.215 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Section 233.215 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 233... acquisition is for— (i) Aircraft (ii) Spacecraft and launch vehicles (iii) Naval vessels (iv) Missile systems...

  14. 48 CFR 233.215 - Contract clause.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Section 233.215 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 233... acquisition is for— (i) Aircraft (ii) Spacecraft and launch vehicles (iii) Naval vessels (iv) Missile systems...

  15. 48 CFR 233.215 - Contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Section 233.215 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 233... acquisition is for— (i) Aircraft (ii) Spacecraft and launch vehicles (iii) Naval vessels (iv) Missile systems...

  16. 49 CFR 234.233 - Rail joints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Rail joints. 234.233 Section 234.233 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... than joint bars and the bonds shall be maintained in such condition to ensure electrical conductivity. ...

  17. 50 CFR 648.233 - Minimum Fish Sizes. [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Minimum Fish Sizes. [Reserved] 648.233 Section 648.233 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND... Measures for the Spiny Dogfish Fishery § 648.233 Minimum Fish Sizes. [Reserved] ...

  18. 40 CFR 233.52 - Program reporting.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Program reporting. 233.52 Section 233.52 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE... cumulative impacts of the State's permit program on the integrity of the State regulated waters...

  19. 40 CFR 233.52 - Program reporting.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Program reporting. 233.52 Section 233.52 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE... cumulative impacts of the State's permit program on the integrity of the State regulated waters...

  20. 28 CFR 115.233 - Resident education.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Resident education. 115.233 Section 115... STANDARDS Standards for Community Confinement Facilities Training and Education § 115.233 Resident education... resident is transferred to a different facility. (c) The agency shall provide resident education in formats...

  1. 28 CFR 115.233 - Resident education.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Resident education. 115.233 Section 115... STANDARDS Standards for Community Confinement Facilities Training and Education § 115.233 Resident education... resident is transferred to a different facility. (c) The agency shall provide resident education in formats...

  2. 28 CFR 115.233 - Resident education.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Resident education. 115.233 Section 115... STANDARDS Standards for Community Confinement Facilities Training and Education § 115.233 Resident education... resident is transferred to a different facility. (c) The agency shall provide resident education in formats...

  3. 45 CFR 233.28 - Monthly reporting.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Monthly reporting. 233.28 Section 233.28 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES COVERAGE AND CONDITIONS OF...

  4. 45 CFR 233.28 - Monthly reporting.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Monthly reporting. 233.28 Section 233.28 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES COVERAGE AND CONDITIONS OF...

  5. 40 CFR 233.39 - Electronic reporting.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Electronic reporting. 233.39 Section... PROGRAM REGULATIONS Program Operation § 233.39 Electronic reporting. States that choose to receive electronic documents must satisfy the requirements of 40 CFR Part 3—(Electronic reporting) in their state...

  6. 40 CFR 233.39 - Electronic reporting.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Electronic reporting. 233.39 Section... PROGRAM REGULATIONS Program Operation § 233.39 Electronic reporting. States that choose to receive electronic documents must satisfy the requirements of 40 CFR Part 3—(Electronic reporting) in their state...

  7. 40 CFR 233.39 - Electronic reporting.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Electronic reporting. 233.39 Section... PROGRAM REGULATIONS Program Operation § 233.39 Electronic reporting. States that choose to receive electronic documents must satisfy the requirements of 40 CFR Part 3—(Electronic reporting) in their state...

  8. 40 CFR 233.39 - Electronic reporting.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Electronic reporting. 233.39 Section... PROGRAM REGULATIONS Program Operation § 233.39 Electronic reporting. States that choose to receive electronic documents must satisfy the requirements of 40 CFR Part 3—(Electronic reporting) in their state...

  9. 40 CFR 233.39 - Electronic reporting.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Electronic reporting. 233.39 Section... PROGRAM REGULATIONS Program Operation § 233.39 Electronic reporting. States that choose to receive electronic documents must satisfy the requirements of 40 CFR Part 3—(Electronic reporting) in their state...

  10. 27 CFR 19.233 - Corporate surety.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Corporate surety. 19.233... OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Bonds and Consents of Surety § 19.233 Corporate surety. (a) Surety bonds required by this part may be given only with corporate sureties holding...

  11. 45 CFR 233.51 - Eligibility of sponsored aliens.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 2 2014-10-01 2012-10-01 true Eligibility of sponsored aliens. 233.51 Section 233... CONDITIONS OF ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.51 Eligibility of sponsored aliens... affidavit(s) of support or similar agreement on behalf of an alien (who is not the child of the sponsor or...

  12. 45 CFR 233.51 - Eligibility of sponsored aliens.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Eligibility of sponsored aliens. 233.51 Section 233... CONDITIONS OF ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.51 Eligibility of sponsored aliens... affidavit(s) of support or similar agreement on behalf of an alien (who is not the child of the sponsor or...

  13. 40 CFR 233.71 - New Jersey.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Protection (and Energy), N.J.S.A. 13:1D-1 et seq. (7) Water Pollution Control Act, N.J.S.A. 58:10A-1 et seq... 40 Protection of Environment 26 2013-07-01 2013-07-01 false New Jersey. 233.71 Section 233.71 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM...

  14. 40 CFR 233.71 - New Jersey.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Protection (and Energy), N.J.S.A. 13:1D-1 et seq. (7) Water Pollution Control Act, N.J.S.A. 58:10A-1 et seq... 40 Protection of Environment 26 2012-07-01 2011-07-01 true New Jersey. 233.71 Section 233.71 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM...

  15. 40 CFR 233.71 - New Jersey.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Protection (and Energy), N.J.S.A. 13:1D-1 et seq. (7) Water Pollution Control Act, N.J.S.A. 58:10A-1 et seq... 40 Protection of Environment 25 2014-07-01 2014-07-01 false New Jersey. 233.71 Section 233.71 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM...

  16. 39 CFR 233.12 - Civil penalties.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 39 Postal Service 1 2013-07-01 2013-07-01 false Civil penalties. 233.12 Section 233.12 Postal... Civil penalties. False representation and lottery orders— (a) Issuance. Pursuant to 39 U.S.C. 3005, the... be liable to the United States for a civil penalty in an amount not to exceed $11,000 for each day...

  17. 39 CFR 233.12 - Civil penalties.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Civil penalties. 233.12 Section 233.12 Postal... Civil penalties. False representation and lottery orders— (a) Issuance. Pursuant to 39 U.S.C. 3005, the... be liable to the United States for a civil penalty in an amount not to exceed $11,000 for each day...

  18. 39 CFR 233.12 - Civil penalties.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Civil penalties. 233.12 Section 233.12 Postal... Civil penalties. False representation and lottery orders— (a) Issuance. Pursuant to 39 U.S.C. 3005, the... be liable to the United States for a civil penalty in an amount not to exceed $11,000 for each day...

  19. 39 CFR 233.12 - Civil penalties.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Civil penalties. 233.12 Section 233.12 Postal... Civil penalties. False representation and lottery orders— (a) Issuance. Pursuant to 39 U.S.C. 3005, the... be liable to the United States for a civil penalty in an amount not to exceed $11,000 for each day...

  20. 7 CFR 1209.233 - Regional caucus chairpersons.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Regional caucus chairpersons. 1209.233 Section 1209.233 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM...

  1. 7 CFR 1209.233 - Regional caucus chairpersons.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Regional caucus chairpersons. 1209.233 Section 1209.233 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM...

  2. 7 CFR 1209.233 - Regional caucus chairpersons.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Regional caucus chairpersons. 1209.233 Section 1209.233 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM...

  3. 7 CFR 1209.233 - Regional caucus chairpersons.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Regional caucus chairpersons. 1209.233 Section 1209.233 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM...

  4. 7 CFR 1209.233 - Regional caucus chairpersons.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Regional caucus chairpersons. 1209.233 Section 1209.233 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM...

  5. 40 CFR 233.10 - Elements of a program submission.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Elements of a program submission. 233.10 Section 233.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM REGULATIONS Program Approval § 233.10 Elements of a program submission. Any State...

  6. 40 CFR 233.10 - Elements of a program submission.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Elements of a program submission. 233.10 Section 233.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM REGULATIONS Program Approval § 233.10 Elements of a program submission. Any State...

  7. 40 CFR 233.10 - Elements of a program submission.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Elements of a program submission. 233.10 Section 233.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM REGULATIONS Program Approval § 233.10 Elements of a program submission. Any State...

  8. 40 CFR 233.10 - Elements of a program submission.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Elements of a program submission. 233.10 Section 233.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM REGULATIONS Program Approval § 233.10 Elements of a program submission. Any State...

  9. 40 CFR 233.10 - Elements of a program submission.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Elements of a program submission. 233.10 Section 233.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM REGULATIONS Program Approval § 233.10 Elements of a program submission. Any State...

  10. 48 CFR 1352.233-70 - Agency protests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Agency protests. 1352.233-70 Section 1352.233-70 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CLAUSES AND..., Chief, Contract Law Division, Room 5893, Herbert C. Hoover Building, 14th Street and Constitution Avenue...

  11. 48 CFR 1352.233-70 - Agency protests.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Agency protests. 1352.233-70 Section 1352.233-70 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CLAUSES AND..., Chief, Contract Law Division, Room 5893, Herbert C. Hoover Building, 14th Street and Constitution Avenue...

  12. 40 CFR 233.51 - Waiver of review.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Waiver of review. 233.51 Section 233.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE...) Discharges with reasonable potential for adverse impacts on waters of another State; (4) Discharges known or...

  13. 40 CFR 233.51 - Waiver of review.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Waiver of review. 233.51 Section 233.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE...) Discharges with reasonable potential for adverse impacts on waters of another State; (4) Discharges known or...

  14. 27 CFR 24.233 - Addition of spirits to wine.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... wine. 24.233 Section 24.233 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS WINE Spirits § 24.233 Addition of spirits to wine. (a) Prior to the addition of spirits. Wine will be placed in tanks approved for the addition of spirits. The...

  15. 22 CFR 233.07 - Fiscal Agent obligations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Fiscal Agent obligations. 233.07 Section 233.07 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113-6-STANDARD TERMS AND...

  16. 22 CFR 233.12 - Prosecution of claims.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Prosecution of claims. 233.12 Section 233.12 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113-6-STANDARD TERMS AND...

  17. 22 CFR 233.11 - Subrogation of USAID.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Subrogation of USAID. 233.11 Section 233.11 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113-6-STANDARD TERMS AND...

  18. 22 CFR 233.13 - Change in agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Change in agreements. 233.13 Section 233.13 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113-6-STANDARD TERMS AND...

  19. 16 CFR 233.5 - Miscellaneous price comparisons.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Miscellaneous price comparisons. 233.5... DECEPTIVE PRICING § 233.5 Miscellaneous price comparisons. The practices covered in the provisions set forth... principles. For example, retailers should not advertise a retail price as a “wholesale” price. They should...

  20. 40 CFR 233.12 - Attorney General's statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Attorney General's statement. 233.12... STATE PROGRAM REGULATIONS Program Approval § 233.12 Attorney General's statement. (a) Any State that seeks to administer a program under this part shall submit a statement from the State Attorney General...

  1. 27 CFR 31.233 - Mixing cocktails in advance of sale.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Mixing cocktails in advance of sale. 31.233 Section 31.233 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS ALCOHOL BEVERAGE DEALERS Miscellaneous § 31.233 Mixing...

  2. 20 CFR 410.233 - Cancellation of a request for withdrawal.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Cancellation of a request for withdrawal. 410.233 Section 410.233 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE HEALTH AND... Entitlement; Filing of Claims and Evidence § 410.233 Cancellation of a request for withdrawal. Before or after...

  3. 40 CFR 52.233 - Review of new sources and modifications.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Review of new sources and modifications. 52.233 Section 52.233 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.233 Review of new sources and modifications. (a) The following...

  4. 40 CFR 52.233 - Review of new sources and modifications.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Review of new sources and modifications. 52.233 Section 52.233 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.233 Review of new sources and modifications. (a) The following...

  5. 40 CFR 52.233 - Review of new sources and modifications.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Review of new sources and modifications. 52.233 Section 52.233 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.233 Review of new sources and modifications. (a) The following...

  6. 40 CFR 233.62 - Procedures for processing an Indian Tribe's application.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Tribe's application. 233.62 Section 233.62 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM REGULATIONS Eligible Indian Tribes § 233.62 Procedures for processing an Indian Tribe's application. (a) The Regional Administrator shall process an application of an...

  7. 40 CFR 233.62 - Procedures for processing an Indian Tribe's application.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Tribe's application. 233.62 Section 233.62 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM REGULATIONS Eligible Indian Tribes § 233.62 Procedures for processing an Indian Tribe's application. (a) The Regional Administrator shall process an application of an...

  8. 40 CFR 233.62 - Procedures for processing an Indian Tribe's application.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Tribe's application. 233.62 Section 233.62 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM REGULATIONS Eligible Indian Tribes § 233.62 Procedures for processing an Indian Tribe's application. (a) The Regional Administrator shall process an application of an...

  9. 39 CFR 233.7 - Forfeiture authority and procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Forfeiture authority and procedures. 233.7 Section 233.7 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION INSPECTION SERVICE... behalf of the Postal Service and the Office of Inspector General to enforce 18 U.S.C. 981, 2254, and 21 U...

  10. 45 CFR 233.51 - Eligibility of sponsored aliens.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false Eligibility of sponsored aliens. 233.51 Section... CONDITIONS OF ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.51 Eligibility of sponsored aliens... affidavit(s) of support or similar agreement on behalf of an alien (who is not the child of the sponsor or...

  11. 45 CFR 233.51 - Eligibility of sponsored aliens.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 2 2012-10-01 2012-10-01 false Eligibility of sponsored aliens. 233.51 Section... CONDITIONS OF ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.51 Eligibility of sponsored aliens... affidavit(s) of support or similar agreement on behalf of an alien (who is not the child of the sponsor or...

  12. 45 CFR 233.51 - Eligibility of sponsored aliens.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Eligibility of sponsored aliens. 233.51 Section... CONDITIONS OF ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.51 Eligibility of sponsored aliens... affidavit(s) of support or similar agreement on behalf of an alien (who is not the child of the sponsor or...

  13. 48 CFR 1852.233-70 - Protests to NASA.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Protests to NASA. 1852.233... 1852.233-70 Protests to NASA. As prescribed in 1833.106-70, insert the following provision: Protests to NASA (OCT 2002) Potential bidders or offerors may submit a protest under 48 CFR part 33 (FAR part 33...

  14. 48 CFR 1852.233-70 - Protests to NASA.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Protests to NASA. 1852.233... 1852.233-70 Protests to NASA. As prescribed in 1833.106-70, insert the following provision: Protests to NASA (OCT 2002) Potential bidders or offerors may submit a protest under 48 CFR part 33 (FAR part 33...

  15. 48 CFR 1852.233-70 - Protests to NASA.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Protests to NASA. 1852.233... 1852.233-70 Protests to NASA. As prescribed in 1833.106-70, insert the following provision: Protests to NASA (OCT 2002) Potential bidders or offerors may submit a protest under 48 CFR part 33 (FAR part 33...

  16. 48 CFR 1852.233-70 - Protests to NASA.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Protests to NASA. 1852.233... 1852.233-70 Protests to NASA. As prescribed in 1833.106-70, insert the following provision: Protests to NASA (OCT 2002) Potential bidders or offerors may submit a protest under 48 CFR part 33 (FAR part 33...

  17. 48 CFR 1852.233-70 - Protests to NASA.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Protests to NASA. 1852.233... 1852.233-70 Protests to NASA. As prescribed in 1833.106-70, insert the following provision: Protests to NASA (OCT 2002) Potential bidders or offerors may submit a protest under 48 CFR part 33 (FAR part 33...

  18. Tumorigenic target cell regions in bone marrow studied by localized dosimetry of 239Pu, 241Am and 233U in the mouse femur.

    PubMed

    Lord, B I; Austin, A L; Ellender, M; Haines, J W; Harrison, J D

    2001-06-01

    To study the temporal change in microdistribution of plutonium-239, americium-241 and uranium-233 in the mouse distal femur and to compare and combine calculated radiation doses with those obtained previously for the femoral shaft. Also, to relate doses to relative risks of osteosarcoma and acute myeloid leukaemia. Computer-based image analysis of neutron-induced and alpha-track autoradiographs of sections of mouse femora was used to quantify the microdistribution of (239)Pu, (241)Am and (233)U from 1 to 448 days after intraperitoneal injection. Localized dose-rates and cumulative doses over this period were calculated for different regions of the marrow spaces in trabecular bone. The results were then combined with previous data for doses to the cortical marrow of the femoral shaft. A morphometric analysis of the distal femur was carried out. Initial deposition on endosteal surfaces and dose-rates near to the trabecular surfaces at 1 day were two to four times greater than corresponding results for cortical bone. Burial was most rapid for (233)U, about twice the rate in cortical bone. As in cortical bone, subsequent uptake into the marrow was seen for (239)Pu and (241)Am but not (233)U. Cumulative doses to 448 days for different regions of trabecular marrow were greater than corresponding values for cortical marrow for each radionuclide. Combined doses reflected the greater overall volume of cortical marrow. Cumulative radiation doses to the 10 microm thick band of marrow adjacent to all endosteal surfaces were in the ratio of approximately 7:3:1 for (239)Pu:(241)Am:(233)U. This ratio is not inconsistent with observed incidences of osteosarcoma induction by the three nuclides. Analysis of doses to different depths of marrow, however, showed that although ratios were probably not significantly different to that for a 10 microm depth, better correlations with osteosarcomagenic risk were obtained with 20-40 microm depths. For acute myeloid leukaemia, the closest

  19. 45 CFR 233.22 - Determining eligibility under prospective budgeting.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Determining eligibility under prospective budgeting. 233.22 Section 233.22 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN...

  20. 45 CFR 233.27 - Supplemental payments under retrospective budgeting.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Supplemental payments under retrospective budgeting. 233.27 Section 233.27 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN...

  1. 45 CFR 233.22 - Determining eligibility under prospective budgeting.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Determining eligibility under prospective budgeting. 233.22 Section 233.22 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN...

  2. 45 CFR 233.27 - Supplemental payments under retrospective budgeting.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Supplemental payments under retrospective budgeting. 233.27 Section 233.27 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN...

  3. 40 CFR 233.50 - Review of and objection to State permits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Review of and objection to State permits. 233.50 Section 233.50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM REGULATIONS Federal Oversight § 233.50 Review of and objection to State permits. (a) The Director shall promptly transmit...

  4. 40 CFR 233.50 - Review of and objection to State permits.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Review of and objection to State permits. 233.50 Section 233.50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM REGULATIONS Federal Oversight § 233.50 Review of and objection to State permits. (a) The Director shall promptly transmit...

  5. 40 CFR 233.50 - Review of and objection to State permits.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Review of and objection to State permits. 233.50 Section 233.50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM REGULATIONS Federal Oversight § 233.50 Review of and objection to State permits. (a) The Director shall promptly transmit...

  6. 40 CFR 233.50 - Review of and objection to State permits.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Review of and objection to State permits. 233.50 Section 233.50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE PROGRAM REGULATIONS Federal Oversight § 233.50 Review of and objection to State permits. (a) The Director shall promptly transmit...

  7. 22 CFR 233.06 - Transferability of Guarantee; Note Register.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Transferability of Guarantee; Note Register. 233.06 Section 233.06 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113...

  8. 12 CFR Appendix A to Part 233 - Model Notice

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) Pt. 233, App. A Appendix A to Part 233... Internet Gambling Enforcement Act Notice Dear [Name of foreign counterparty]: On [date], U.S. government officials informed us that your institution processed payments through our facilities for Internet gambling...

  9. 12 CFR Appendix A to Part 233 - Model Notice

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) Pt. 233, App. A Appendix A to Part 233... Internet Gambling Enforcement Act Notice Dear [Name of foreign counterparty]: On [date], U.S. government officials informed us that your institution processed payments through our facilities for Internet gambling...

  10. 12 CFR Appendix A to Part 233 - Model Notice

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) Pt. 233, App. A Appendix A to Part 233... Internet Gambling Enforcement Act Notice Dear [Name of foreign counterparty]: On [date], U.S. government officials informed us that your institution processed payments through our facilities for Internet gambling...

  11. 12 CFR Appendix A to Part 233 - Model Notice

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) Part 233, App. A Appendix A to Part 233—Model Notice [Date] [Name of foreign sender or foreign banking office] [Address] Re: U.S. Unlawful Internet Gambling... that your institution processed payments through our facilities for Internet gambling transactions...

  12. 12 CFR Appendix A to Part 233 - Model Notice

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) Part 233, App. A Appendix A to Part 233—Model Notice [Date] [Name of foreign sender or foreign banking office] [Address] Re: U.S. Unlawful Internet Gambling... that your institution processed payments through our facilities for Internet gambling transactions...

  13. 22 CFR 233.05 - Non-impairment of the Guarantee.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Non-impairment of the Guarantee. 233.05 Section 233.05 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113-6-STANDARD TERMS...

  14. 22 CFR 233.09 - No acceleration of Eligible Notes.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false No acceleration of Eligible Notes. 233.09 Section 233.09 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113-6-STANDARD TERMS...

  15. 49 CFR 233.5 - Accidents resulting from signal failure.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Accidents resulting from signal failure. 233.5... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.5 Accidents resulting... required by part 236 of this title that results in a more favorable aspect than intended or other condition...

  16. 49 CFR 233.5 - Accidents resulting from signal failure.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Accidents resulting from signal failure. 233.5... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.5 Accidents resulting... required by part 236 of this title that results in a more favorable aspect than intended or other condition...

  17. 49 CFR 233.5 - Accidents resulting from signal failure.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Accidents resulting from signal failure. 233.5... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.5 Accidents resulting... required by part 236 of this title that results in a more favorable aspect than intended or other condition...

  18. 49 CFR 233.5 - Accidents resulting from signal failure.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Accidents resulting from signal failure. 233.5... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.5 Accidents resulting... required by part 236 of this title that results in a more favorable aspect than intended or other condition...

  19. 49 CFR 233.5 - Accidents resulting from signal failure.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Accidents resulting from signal failure. 233.5... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.5 Accidents resulting... required by part 236 of this title that results in a more favorable aspect than intended or other condition...

  20. 42 CFR 2.33 - Disclosures permitted with written consent.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Disclosures permitted with written consent. 2.33 Section 2.33 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CONFIDENTIALITY OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures With Patient's Consent § 2...

  1. 42 CFR 2.33 - Disclosures permitted with written consent.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Disclosures permitted with written consent. 2.33 Section 2.33 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CONFIDENTIALITY OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures With Patient's Consent § 2...

  2. 42 CFR 2.33 - Disclosures permitted with written consent.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Disclosures permitted with written consent. 2.33 Section 2.33 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CONFIDENTIALITY OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures With Patient's Consent § 2...

  3. 42 CFR 2.33 - Disclosures permitted with written consent.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Disclosures permitted with written consent. 2.33 Section 2.33 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CONFIDENTIALITY OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures With Patient's Consent § 2...

  4. 42 CFR 2.33 - Disclosures permitted with written consent.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Disclosures permitted with written consent. 2.33 Section 2.33 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CONFIDENTIALITY OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures With Patient's Consent § 2...

  5. Three Small Planets Transiting the Bright Young Field Star K2-233

    NASA Astrophysics Data System (ADS)

    David, Trevor J.; Crossfield, Ian J. M.; Benneke, Björn; Petigura, Erik A.; Gonzales, Erica J.; Schlieder, Joshua E.; Yu, Liang; Isaacson, Howard T.; Howard, Andrew W.; Ciardi, David R.; Mamajek, Eric E.; Hillenbrand, Lynne A.; Cody, Ann Marie; Riedel, Adric; Schwengeler, Hans Martin; Tanner, Christopher; Ende, Martin

    2018-05-01

    We report the detection of three small transiting planets around the young K3 dwarf K2-233 (2MASS J15215519‑2013539) from observations during Campaign 15 of the K2 mission. The star is relatively nearby (d = 69 pc) and bright (V = 10.7 mag, K s = 8.4 mag), making the planetary system an attractive target for radial velocity follow-up and atmospheric characterization with the James Webb Space Telescope. The inner two planets are hot super-Earths (R b = 1.40 ± 0.06 {R}\\oplus , R c = 1.34 ± 0.08 {R}\\oplus ), while the outer planet is a warm sub-Neptune (R d = 2.6 ± 0.1 {R}\\oplus ). We estimate the stellar age to be {360}-140+490 Myr based on rotation, activity, and kinematic indicators. The K2-233 system is particularly interesting given recent evidence for inflated radii in planets around similarly aged stars, a trend potentially related to photo-evaporation, core cooling, or both mechanisms.

  6. 48 CFR 252.233-7001 - Choice of law (overseas).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Choice of law (overseas... of Provisions And Clauses 252.233-7001 Choice of law (overseas). As prescribed in 233.215-70, use the following clause: Choice of Law (Overseas) (JUN 1997) This contract shall be construed and interpreted in...

  7. 49 CFR 233.1 - Scope.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.1 Scope. This part prescribed reporting requirements with respect to methods of train operation, block signal systems, interlockings, traffic control systems, automatic train stop, train control, and cab signal systems, or other similar appliances, methods...

  8. 49 CFR 233.1 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... TRANSPORTATION SIGNAL SYSTEMS REPORTING REQUIREMENTS § 233.1 Scope. This part prescribed reporting requirements with respect to methods of train operation, block signal systems, interlockings, traffic control systems, automatic train stop, train control, and cab signal systems, or other similar appliances, methods...

  9. 28 CFR 23.3 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.3 Applicability. (a) These policy standards are applicable to all criminal intelligence systems operating through support...-647). (b) As used in these policies: (1) Criminal Intelligence System or Intelligence System means the...

  10. 28 CFR 23.3 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.3 Applicability. (a) These policy standards are applicable to all criminal intelligence systems operating through support...-647). (b) As used in these policies: (1) Criminal Intelligence System or Intelligence System means the...

  11. 28 CFR 23.3 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.3 Applicability. (a) These policy standards are applicable to all criminal intelligence systems operating through support...-647). (b) As used in these policies: (1) Criminal Intelligence System or Intelligence System means the...

  12. 28 CFR 23.3 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.3 Applicability. (a) These policy standards are applicable to all criminal intelligence systems operating through support...-647). (b) As used in these policies: (1) Criminal Intelligence System or Intelligence System means the...

  13. 28 CFR 23.3 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.3 Applicability. (a) These policy standards are applicable to all criminal intelligence systems operating through support...-647). (b) As used in these policies: (1) Criminal Intelligence System or Intelligence System means the...

  14. 7 CFR 1280.233 - Referenda.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE LAMB PROMOTION, RESEARCH, AND INFORMATION ORDER Lamb Promotion, Research, and Information Order Miscellaneous § 1280.233 Referenda. (a... determined by the Secretary, have engaged in the production, feeding, handling, or slaughter of lamb; or the...

  15. 45 CFR 233.32 - Payment and budget months (AFDC).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Payment and budget months (AFDC). 233.32 Section... CONDITIONS OF ELIGIBILITY IN FINANCIAL ASSISTANCE PROGRAMS § 233.32 Payment and budget months (AFDC). A State... period used to determine that payment (budget month) and whether it adopts (a) a one-month or two-month...

  16. 800-MeV proton irradiation of thorium and depleted uranium targets

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Russell, G.J.; Brun, T.O.; Pitcher, E.J.

    As part of the Los Alamos Fertile-to-Fissile-Conversion (FERFICON) program in the late 1980`s, thick targets of the fertile materials thorium and depleted uranium were bombarded by 800-MeV protons to produce the fissile materials {sup 233}U and {sup 239}Pu, respectively. The amount of {sup 233}U made was determined by measuring the {sup 233}Pa activity, and the yield of {sup 239}Pu was deduced by measuring the activity of {sup 239}Np. For the thorium target, 4 spallation products and 34 fission products were also measured. For the depleted uranium target, 3 spallation products and 16 fission products were also measured. The number ofmore » fissions in each target was deduced from fission product mass-yield curves. In actuality, axial distributions of the products were measured, and the distributions were then integrated over the target volume to obtain the total number of products for each reaction.« less

  17. 48 CFR 1352.233-71 - GAO and Court of Federal Claims protests.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false GAO and Court of Federal Claims protests. 1352.233-71 Section 1352.233-71 Federal Acquisition Regulations System DEPARTMENT OF....233-71 GAO and Court of Federal Claims protests. As prescribed in 48 CFR 1333.104-70(a), insert the...

  18. 48 CFR 1352.233-71 - GAO and Court of Federal Claims protests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false GAO and Court of Federal Claims protests. 1352.233-71 Section 1352.233-71 Federal Acquisition Regulations System DEPARTMENT OF....233-71 GAO and Court of Federal Claims protests. As prescribed in 48 CFR 1333.104-70(a), insert the...

  19. Modelling Symmetry Classes 233 and 432.

    ERIC Educational Resources Information Center

    Dutch, Steven I.

    1986-01-01

    Offers instructions and geometrical data for constructing solids of the enantiomorphous symmetry classes 233 and 432. Provides background information for each class and highlights symmetrical relationships and construction patterns. (ML)

  20. 45 CFR 233.10 - General provisions regarding coverage and eligibility.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true General provisions regarding coverage and eligibility. 233.10 Section 233.10 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN...

  1. 22 CFR 233.01 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113-6-STANDARD TERMS AND CONDITIONS § 233.01... Department of State, Foreign Operations, and Related Programs Appropriations Act, 2012, (Div. I, Pub. L. 112...

  2. 47 CFR 90.233 - Base/mobile non-voice operations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Base/mobile non-voice operations. 90.233... SERVICES PRIVATE LAND MOBILE RADIO SERVICES Non-Voice and Other Specialized Operations § 90.233 Base/mobile non-voice operations. The use of A1D, A2D, F1D, F2D, G1D, or G2D emission may be authorized to base...

  3. 47 CFR 90.233 - Base/mobile non-voice operations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Base/mobile non-voice operations. 90.233... SERVICES PRIVATE LAND MOBILE RADIO SERVICES Non-Voice and Other Specialized Operations § 90.233 Base/mobile non-voice operations. The use of A1D, A2D, F1D, F2D, G1D, or G2D emission may be authorized to base...

  4. 47 CFR 90.233 - Base/mobile non-voice operations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Base/mobile non-voice operations. 90.233... SERVICES PRIVATE LAND MOBILE RADIO SERVICES Non-Voice and Other Specialized Operations § 90.233 Base/mobile non-voice operations. The use of A1D, A2D, F1D, F2D, G1D, or G2D emission may be authorized to base...

  5. 47 CFR 90.233 - Base/mobile non-voice operations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Base/mobile non-voice operations. 90.233... SERVICES PRIVATE LAND MOBILE RADIO SERVICES Non-Voice and Other Specialized Operations § 90.233 Base/mobile non-voice operations. The use of A1D, A2D, F1D, F2D, G1D, or G2D emission may be authorized to base...

  6. 9 CFR 2.33 - Attending veterinarian and adequate veterinary care.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... animal health, behavior, and well-being is conveyed to the attending veterinarian; (4) Guidance to... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Attending veterinarian and adequate veterinary care. 2.33 Section 2.33 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...

  7. 9 CFR 2.33 - Attending veterinarian and adequate veterinary care.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... animal health, behavior, and well-being is conveyed to the attending veterinarian; (4) Guidance to... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Attending veterinarian and adequate veterinary care. 2.33 Section 2.33 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...

  8. 9 CFR 2.33 - Attending veterinarian and adequate veterinary care.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... animal health, behavior, and well-being is conveyed to the attending veterinarian; (4) Guidance to... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Attending veterinarian and adequate veterinary care. 2.33 Section 2.33 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...

  9. 9 CFR 2.33 - Attending veterinarian and adequate veterinary care.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... veterinary care. 2.33 Section 2.33 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... adequate veterinary care. (a) Each research facility shall have an attending veterinarian who shall provide adequate veterinary care to its animals in compliance with this section: (1) Each research facility shall...

  10. 9 CFR 2.33 - Attending veterinarian and adequate veterinary care.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... veterinary care. 2.33 Section 2.33 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... adequate veterinary care. (a) Each research facility shall have an attending veterinarian who shall provide adequate veterinary care to its animals in compliance with this section: (1) Each research facility shall...

  11. 5 CFR 532.233 - Preparation for full-scale wage surveys.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... presence on the job, and the prudent management of available financial and human resources. Employing.... 532.233 Section 532.233 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE... and jobs to be covered in the wage survey. (2) Shall prepare a summary of the hearings and submit it...

  12. 45 CFR 233.110 - Foster care maintenance and adoption assistance.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 2 2012-10-01 2012-10-01 false Foster care maintenance and adoption assistance. 233.110 Section 233.110 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY... maintenance and adoption assistance. (a) State plan requirements. A State plan under title IV-A of the Social...

  13. 45 CFR 233.110 - Foster care maintenance and adoption assistance.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 2 2014-10-01 2012-10-01 true Foster care maintenance and adoption assistance. 233.110 Section 233.110 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY... maintenance and adoption assistance. (a) State plan requirements. A State plan under title IV-A of the Social...

  14. 45 CFR 233.110 - Foster care maintenance and adoption assistance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Foster care maintenance and adoption assistance. 233.110 Section 233.110 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY... maintenance and adoption assistance. (a) State plan requirements. A State plan under title IV-A of the Social...

  15. 45 CFR 233.110 - Foster care maintenance and adoption assistance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false Foster care maintenance and adoption assistance. 233.110 Section 233.110 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY... maintenance and adoption assistance. (a) State plan requirements. A State plan under title IV-A of the Social...

  16. 45 CFR 233.110 - Foster care maintenance and adoption assistance.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Foster care maintenance and adoption assistance. 233.110 Section 233.110 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY... maintenance and adoption assistance. (a) State plan requirements. A State plan under title IV-A of the Social...

  17. 22 CFR 233.15 - Notice.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113-6-STANDARD TERMS AND CONDITIONS § 233.15 Notice. Any... complete on the day it shall be actually received by USAID at the Office of Development Credit, Bureau for...

  18. Production of medical isotopes from a thorium target irradiated by light charged particles up to 70 MeV

    NASA Astrophysics Data System (ADS)

    Duchemin, C.; Guertin, A.; Haddad, F.; Michel, N.; Métivier, V.

    2015-02-01

    The irradiation of a thorium target by light charged particles (protons and deuterons) leads to the production of several isotopes of medical interest. Direct nuclear reaction allows the production of Protactinium-230 which decays to Uranium-230 the mother nucleus of Thorium-226, a promising isotope for alpha radionuclide therapy. The fission of Thorium-232 produces fragments of interest like Molybdenum-99, Iodine-131 and Cadmium-115g. We focus our study on the production of these isotopes, performing new cross section measurements and calculating production yields. Our new sets of data are compared with the literature and the last version of the TALYS code.

  19. Production of medical isotopes from a thorium target irradiated by light charged particles up to 70 MeV.

    PubMed

    Duchemin, C; Guertin, A; Haddad, F; Michel, N; Métivier, V

    2015-02-07

    The irradiation of a thorium target by light charged particles (protons and deuterons) leads to the production of several isotopes of medical interest. Direct nuclear reaction allows the production of Protactinium-230 which decays to Uranium-230 the mother nucleus of Thorium-226, a promising isotope for alpha radionuclide therapy. The fission of Thorium-232 produces fragments of interest like Molybdenum-99, Iodine-131 and Cadmium-115g. We focus our study on the production of these isotopes, performing new cross section measurements and calculating production yields. Our new sets of data are compared with the literature and the last version of the TALYS code.

  20. 22 CFR 233.08 - Event of default; Application for Compensation; payment.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Event of default; Application for Compensation; payment. 233.08 Section 233.08 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113...

  1. 40 CFR 233.52 - Program reporting.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... period to be covered by reports shall be established in the Memorandum of Agreement with the Regional Administrator (§ 233.13.) (b) The Director shall submit to the Regional Administrator within 90 days after... cumulative impacts of the State's permit program on the integrity of the State regulated waters...

  2. 40 CFR 233.52 - Program reporting.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... period to be covered by reports shall be established in the Memorandum of Agreement with the Regional Administrator (§ 233.13.) (b) The Director shall submit to the Regional Administrator within 90 days after... cumulative impacts of the State's permit program on the integrity of the State regulated waters...

  3. 40 CFR 233.52 - Program reporting.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... period to be covered by reports shall be established in the Memorandum of Agreement with the Regional Administrator (§ 233.13.) (b) The Director shall submit to the Regional Administrator within 90 days after... cumulative impacts of the State's permit program on the integrity of the State regulated waters...

  4. 50 CFR 23.3 - What other wildlife and plant regulations may apply?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 9 2012-10-01 2012-10-01 false What other wildlife and plant regulations may apply? 23.3 Section 23.3 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE..., EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS (CONTINUED) CONVENTION ON INTERNATIONAL TRADE IN...

  5. 50 CFR 23.3 - What other wildlife and plant regulations may apply?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 8 2011-10-01 2011-10-01 false What other wildlife and plant regulations may apply? 23.3 Section 23.3 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE..., EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS (CONTINUED) CONVENTION ON INTERNATIONAL TRADE IN...

  6. 50 CFR 23.3 - What other wildlife and plant regulations may apply?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 9 2014-10-01 2014-10-01 false What other wildlife and plant regulations may apply? 23.3 Section 23.3 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE..., EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS (CONTINUED) CONVENTION ON INTERNATIONAL TRADE IN...

  7. 50 CFR 23.3 - What other wildlife and plant regulations may apply?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 9 2013-10-01 2013-10-01 false What other wildlife and plant regulations may apply? 23.3 Section 23.3 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE..., EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS (CONTINUED) CONVENTION ON INTERNATIONAL TRADE IN...

  8. 50 CFR 23.3 - What other wildlife and plant regulations may apply?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false What other wildlife and plant regulations may apply? 23.3 Section 23.3 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE..., EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS (CONTINUED) CONVENTION ON INTERNATIONAL TRADE IN...

  9. 45 CFR 233.23 - When assistance shall be paid under retrospective budgeting.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false When assistance shall be paid under retrospective budgeting. 233.23 Section 233.23 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN...

  10. 45 CFR 233.23 - When assistance shall be paid under retrospective budgeting.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true When assistance shall be paid under retrospective budgeting. 233.23 Section 233.23 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN...

  11. 45 CFR 233.21 - Budgeting methods for OAA, AB, APTD, and AABD.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Budgeting methods for OAA, AB, APTD, and AABD. 233.21 Section 233.21 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

  12. 45 CFR 233.21 - Budgeting methods for OAA, AB, APTD, and AABD.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Budgeting methods for OAA, AB, APTD, and AABD. 233.21 Section 233.21 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

  13. 30 CFR 285.233-285.234 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....234 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Noncompetitive Lease Award Process §§ 285.233-285.234 [Reserved] Commercial and Limited...

  14. 12 CFR 233.5 - Policies and procedures required.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... SYSTEM (CONTINUED) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.5 Policies... “unlawful Internet gambling” in the Act as an intrastate transaction, an intratribal transaction, or a...

  15. 12 CFR 233.5 - Policies and procedures required.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... SYSTEM (CONTINUED) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.5 Policies... “unlawful Internet gambling” in the Act as an intrastate transaction, an intratribal transaction, or a...

  16. 12 CFR 233.5 - Policies and procedures required.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... SYSTEM (CONTINUED) PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.5 Policies... “unlawful Internet gambling” in the Act as an intrastate transaction, an intratribal transaction, or a...

  17. 12 CFR 233.5 - Policies and procedures required.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... SYSTEM PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.5 Policies and... “unlawful Internet gambling” in the Act as an intrastate transaction, an intratribal transaction, or a...

  18. 12 CFR 233.5 - Policies and procedures required.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SYSTEM PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.5 Policies and... “unlawful Internet gambling” in the Act as an intrastate transaction, an intratribal transaction, or a...

  19. 30 CFR 285.233-285.234 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....234 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Noncompetitive Lease Award Process §§ 285.233-285.234...

  20. 40 CFR 233.41 - Requirements for enforcement authority.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) The Regional Administrator may approve a State program where the State lacks authority to recover... enforcement authority (§ 233.41(a)(3) (ii) and (iii)), the Federal government will continue to exercise...

  1. SELECTIVE SEPARATION OF URANIUM FROM THORIUM, PROTACTINIUM AND FISSION PRODUCTS BY PEROXIDE DISSOLUTION METHOD

    DOEpatents

    Seaborg, G.T.; Gofman, J.W.; Stoughton, R.W.

    1959-08-18

    A method is described for separating U/sup 233/ from thorium and fission products. The separation is effected by forming a thorium-nitric acid solution of about 3 pH, adding hydrogen peroxide to precipitate uranium and thorium peroxide, treating the peroxides with sodium hydroxide to selectively precipitate the uranium peroxide, and reacting the separated solution with nitric acid to re- precipitate the uranium peroxide.

  2. Uranium-233 waste definition: Disposal options, safeguards, criticality control, and arms control

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Forsberg, C.W.; Storch, S.N.; Lewis, L.C.

    1998-07-07

    The US investigated the use of {sup 233}U for weapons, reactors, and other purposes from the 1950s into the 1970s. Based on the results of these investigations, it was decided not to use {sup 233}U on a large scale. Most of the {sup 233}U-containing materials were placed in long-term storage. At the end of the cold war, the US initiated, as part of its arms control policies, a disposition program for excess fissile materials. Other programs were accelerated for disposal of radioactive wastes placed in storage during the cold war. Last, potential safety issues were identified related to the storagemore » of some {sup 233}U-containing materials. Because of these changes, significant activities associated with {sup 233}U-containing materials are expected. This report is one of a series of reports to provide the technical bases for future decisions on how to manage this material. A basis for defining when {sup 233}U-containing materials can be managed as waste and when they must be managed as concentrated fissile materials has been developed. The requirements for storage, transport, and disposal of radioactive wastes are significantly different than those for fissile materials. Because of these differences, it is important to classify material in its appropriate category. The establishment of a definition of what is waste and what is fissile material will provide the guidance for appropriate management of these materials. Wastes are defined in this report as materials containing sufficiently small masses or low concentrations of fissile materials such that they can be managed as typical radioactive waste. Concentrated fissile materials are defined herein as materials containing sufficient fissile content such as to warrant special handling to address nuclear criticality, safeguards, and arms control concerns.« less

  3. 30 CFR 585.233-585.234 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....234 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Noncompetitive Lease Award Process §§ 585.233-585.234 [Reserved] Commercial and Limited...

  4. 30 CFR 585.233-585.234 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ....234 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Noncompetitive Lease Award Process §§ 585.233-585.234 [Reserved] Commercial and Limited...

  5. 30 CFR 585.233-585.234 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....234 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Noncompetitive Lease Award Process §§ 585.233-585.234 [Reserved] Commercial and Limited...

  6. 48 CFR 5452.233-9001 - Disputes: Agreement To Use Alternative Dispute Resolution (ADR).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Disputes: Agreement To Use Alternative Dispute Resolution (ADR). 5452.233-9001 Section 5452.233-9001 Federal Acquisition Regulations System DEFENSE LOGISTICS AGENCY, DEPARTMENT OF DEFENSE SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts...

  7. 48 CFR 5452.233-9001 - Disputes: Agreement To Use Alternative Dispute Resolution (ADR).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Disputes: Agreement To Use Alternative Dispute Resolution (ADR). 5452.233-9001 Section 5452.233-9001 Federal Acquisition Regulations System DEFENSE LOGISTICS AGENCY, DEPARTMENT OF DEFENSE SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts...

  8. 48 CFR 5452.233-9001 - Disputes: Agreement To Use Alternative Dispute Resolution (ADR).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Disputes: Agreement To Use Alternative Dispute Resolution (ADR). 5452.233-9001 Section 5452.233-9001 Federal Acquisition Regulations System DEFENSE LOGISTICS AGENCY, DEPARTMENT OF DEFENSE SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts...

  9. 48 CFR 5452.233-9001 - Disputes: Agreement To Use Alternative Dispute Resolution (ADR).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Disputes: Agreement To Use Alternative Dispute Resolution (ADR). 5452.233-9001 Section 5452.233-9001 Federal Acquisition Regulations System DEFENSE LOGISTICS AGENCY, DEPARTMENT OF DEFENSE SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts...

  10. 46 CFR 153.233 - Separation of tanks from machinery, service and other spaces.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... spaces. 153.233 Section 153.233 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS... other spaces. (a) To prevent leakage through a single weld failure, the following spaces must be...

  11. 46 CFR 153.233 - Separation of tanks from machinery, service and other spaces.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... spaces. 153.233 Section 153.233 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS... other spaces. (a) To prevent leakage through a single weld failure, the following spaces must be...

  12. 46 CFR 153.233 - Separation of tanks from machinery, service and other spaces.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... spaces. 153.233 Section 153.233 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS... other spaces. (a) To prevent leakage through a single weld failure, the following spaces must be...

  13. 46 CFR 153.233 - Separation of tanks from machinery, service and other spaces.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... spaces. 153.233 Section 153.233 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS... other spaces. (a) To prevent leakage through a single weld failure, the following spaces must be...

  14. 46 CFR 153.233 - Separation of tanks from machinery, service and other spaces.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... spaces. 153.233 Section 153.233 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS... other spaces. (a) To prevent leakage through a single weld failure, the following spaces must be...

  15. 48 CFR 5452.233-9001 - Disputes: Agreement To Use Alternative Dispute Resolution (ADR).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Alternative Dispute Resolution (ADR). 5452.233-9001 Section 5452.233-9001 Federal Acquisition Regulations... (ADR). As prescribed in 5433.214, insert the following provision: Disputes: Agreement To Use Alternative Dispute Resolution (ADR) (APR 2001)—DLAD (a) The parties agree to negotiate with each other to try...

  16. 24 CFR 5.233 - Mandated use of HUD's Enterprise Income Verification (EIV) System.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Mandated use of HUD's Enterprise Income Verification (EIV) System. 5.233 Section 5.233 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development GENERAL HUD PROGRAM REQUIREMENTS; WAIVERS Disclosure...

  17. 40 CFR 233.51 - Waiver of review.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... REGULATIONS Federal Oversight § 233.51 Waiver of review. (a) The MOA with the Regional Administrator shall... discharge for which EPA will waive review. The Regional Administrator shall consult with the Corps, FWS, and... reasonable potential for adverse impacts on waters of another State; (4) Discharges known or suspected to...

  18. 30 CFR 550.233 - What decisions will BOEM make on the EP and within what timeframe?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false What decisions will BOEM make on the EP and within what timeframe? 550.233 Section 550.233 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT... and Information Review and Decision Process for the Ep § 550.233 What decisions will BOEM make on the...

  19. 30 CFR 250.233 - What decisions will MMS make on the EP and within what timeframe?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What decisions will MMS make on the EP and within what timeframe? 250.233 Section 250.233 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT... Information Review and Decision Process for the Ep § 250.233 What decisions will MMS make on the EP and within...

  20. 30 CFR 550.233 - What decisions will BOEM make on the EP and within what timeframe?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false What decisions will BOEM make on the EP and within what timeframe? 550.233 Section 550.233 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT... and Information Review and Decision Process for the Ep § 550.233 What decisions will BOEM make on the...

  1. 30 CFR 550.233 - What decisions will BOEM make on the EP and within what timeframe?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false What decisions will BOEM make on the EP and within what timeframe? 550.233 Section 550.233 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT... and Information Review and Decision Process for the Ep § 550.233 What decisions will BOEM make on the...

  2. 46 CFR 108.233 - Location and size.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... EQUIPMENT Construction and Arrangement Helicopter Facilities § 108.233 Location and size. (a) Each helicopter deck must be— (1) At least the size of the rotor diameter of the largest single main rotor helicopter that will be used on the facility; or (2) If tandem main rotor helicopters use the facility, at...

  3. 46 CFR 108.233 - Location and size.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... EQUIPMENT Construction and Arrangement Helicopter Facilities § 108.233 Location and size. (a) Each helicopter deck must be— (1) At least the size of the rotor diameter of the largest single main rotor helicopter that will be used on the facility; or (2) If tandem main rotor helicopters use the facility, at...

  4. 46 CFR 108.233 - Location and size.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... EQUIPMENT Construction and Arrangement Helicopter Facilities § 108.233 Location and size. (a) Each helicopter deck must be— (1) At least the size of the rotor diameter of the largest single main rotor helicopter that will be used on the facility; or (2) If tandem main rotor helicopters use the facility, at...

  5. 46 CFR 108.233 - Location and size.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... EQUIPMENT Construction and Arrangement Helicopter Facilities § 108.233 Location and size. (a) Each helicopter deck must be— (1) At least the size of the rotor diameter of the largest single main rotor helicopter that will be used on the facility; or (2) If tandem main rotor helicopters use the facility, at...

  6. 46 CFR 108.233 - Location and size.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... EQUIPMENT Construction and Arrangement Helicopter Facilities § 108.233 Location and size. (a) Each helicopter deck must be— (1) At least the size of the rotor diameter of the largest single main rotor helicopter that will be used on the facility; or (2) If tandem main rotor helicopters use the facility, at...

  7. 47 CFR 51.233 - Significant degradation of services caused by deployment of advanced services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... deployment of advanced services. 51.233 Section 51.233 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... relevant state commission that a particular technology deployment is causing the significant degradation..., the relevant state commission, must be supported with specific and verifiable information. (d) Where a...

  8. 21 CFR 1.233 - What optional items are included in the registration form?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... extracts) and 11b (e.g., grain products, amino acids); (i) Type of storage, if the facility is primarily a... 21 Food and Drugs 1 2010-04-01 2010-04-01 false What optional items are included in the registration form? 1.233 Section 1.233 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND...

  9. 21 CFR 1.233 - What optional items are included in the registration form?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... extracts) and 11b (e.g., grain products, amino acids); (i) Type of storage, if the facility is primarily a... 21 Food and Drugs 1 2011-04-01 2011-04-01 false What optional items are included in the registration form? 1.233 Section 1.233 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND...

  10. 45 CFR 233.29 - How monthly reports are treated and what notices are required.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true How monthly reports are treated and what notices are required. 233.29 Section 233.29 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH...

  11. 45 CFR 233.29 - How monthly reports are treated and what notices are required.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false How monthly reports are treated and what notices are required. 233.29 Section 233.29 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH...

  12. 22 CFR 233.10 - Payment to USAID of excess amounts received by a Noteholder.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Payment to USAID of excess amounts received by a Noteholder. 233.10 Section 233.10 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F...

  13. Induction of keratinocyte migration by ECa 233 is mediated through FAK/Akt, ERK, and p38 MAPK signaling.

    PubMed

    Singkhorn, Sawana; Tantisira, Mayuree H; Tanasawet, Supita; Hutamekalin, Pilaiwanwadee; Wongtawatchai, Tulaporn; Sukketsiri, Wanida

    2018-03-13

    Centella asiatica is widely considered the most important medicinal plant for treating and relieving skin diseases. Recently developed standardized extract of Centella asiatica ECa 233 has demonstrated positive effects on wound healing of incision and burn wound in rats. However, knowledge associated with wound healing mechanism of ECa 233 was scare. Therefore, this study aimed to investigate the effect and underlying molecular mechanisms of ECa 233 on the migration of a human keratinocyte cell line (HaCaT) using scratch wound healing assay. Formation of filopodia, a key protein in cell migration as well as signaling pathways possibly involved were subsequently assessed. It was found that HaCaT cell migration was significantly enhanced by ECa 233 in a concentration- and time-dependent manner. The filopodia formations were accordingly increased in exposure to ECa 233 at concentrations of 0.1-100 μg/ml. Furthermore, ECa 233 was found to significantly upregulate the expression of Rac1 and RhoA and to induce phosphorylation of FAK and Akt as well as ERK and p38 MAPK. Taken all together, it is suggestive that ECa 233 induces cell migration and subsequently promotes wound healing activity, through the activation of FAK, Akt, and MAPK signaling pathways thereby supporting the role of ECa 233 to be further developed for the clinical treatment of wound. Copyright © 2018 John Wiley & Sons, Ltd.

  14. Evaluation of ENDF/B-IV and Hansen--Roach /sup 233/U cross sections for use in criticality calculations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McNeany, S.R.; Jenkins, J.D.

    Eleven /sup 233/U solution critical assemblies spanning an H//sup 233/U ratio range of 40 to 2000 and an unreflected metal /sup 233/U assembly were calculated with ENDF/B-IV and Hansen--Roach cross sections. Results from these calculations are compared with the experimental results and with each other. An increasing disagreement is observed between calculations with ENDF/B and Hansen--Roach data with decreasing H//sup 233/U ratio, indicative of large differences in their intermediate-energy cross sections. The Hansen--Roach cross sections appeared to give reasonably good agreement with experiments over the whole range, whereas the ENDF/B calculations yielded high values for k/sub eff/ on assemblies ofmore » low moderation. It is concluded that serious problems exist in the ENDF/B-IV representation of the /sup 233/U cross sections in the intermediate energy range and that further evaluation of this nuclide is warranted. In addition, it is recommended that an experimental program be undertaken to obtain /sup 233/U criticality data at low H//sup 233/U ratios for verification of generalized criticality safety guidelines. 3 figures, 15 tables.« less

  15. 27 CFR 46.233 - Payment of floor stocks tax.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... PRODUCTS AND CIGARETTE PAPERS AND TUBES Floor Stocks Tax on Certain Tobacco Products, Cigarette Papers, and Cigarette Tubes Held for Sale on April 1, 2009 Filing Requirements § 46.233 Payment of floor stocks tax. (a...

  16. 27 CFR 46.233 - Payment of floor stocks tax.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... PRODUCTS AND CIGARETTE PAPERS AND TUBES Floor Stocks Tax on Certain Tobacco Products, Cigarette Papers, and Cigarette Tubes Held for Sale on April 1, 2009 Filing Requirements § 46.233 Payment of floor stocks tax. (a...

  17. 27 CFR 46.233 - Payment of floor stocks tax.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... PRODUCTS AND CIGARETTE PAPERS AND TUBES Floor Stocks Tax on Certain Tobacco Products, Cigarette Papers, and Cigarette Tubes Held for Sale on April 1, 2009 Filing Requirements § 46.233 Payment of floor stocks tax. (a...

  18. 27 CFR 46.233 - Payment of floor stocks tax.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... PRODUCTS AND CIGARETTE PAPERS AND TUBES Floor Stocks Tax on Certain Tobacco Products, Cigarette Papers, and Cigarette Tubes Held for Sale on April 1, 2009 Filing Requirements § 46.233 Payment of floor stocks tax. (a...

  19. 40 CFR 233.61 - Determination of Tribal eligibility.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the Safe Drinking Water Act or the Clean Water Act, then that Tribe need only provide additional... DUMPING 404 STATE PROGRAM REGULATIONS Eligible Indian Tribes § 233.61 Determination of Tribal eligibility. An Indian Tribe may apply to the Regional Administrator for a determination that it meets the...

  20. 40 CFR 233.61 - Determination of Tribal eligibility.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the Safe Drinking Water Act or the Clean Water Act, then that Tribe need only provide additional... DUMPING 404 STATE PROGRAM REGULATIONS Eligible Indian Tribes § 233.61 Determination of Tribal eligibility. An Indian Tribe may apply to the Regional Administrator for a determination that it meets the...

  1. 40 CFR 233.61 - Determination of Tribal eligibility.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the Safe Drinking Water Act or the Clean Water Act, then that Tribe need only provide additional... DUMPING 404 STATE PROGRAM REGULATIONS Eligible Indian Tribes § 233.61 Determination of Tribal eligibility. An Indian Tribe may apply to the Regional Administrator for a determination that it meets the...

  2. 40 CFR 233.61 - Determination of Tribal eligibility.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the Safe Drinking Water Act or the Clean Water Act, then that Tribe need only provide additional... DUMPING 404 STATE PROGRAM REGULATIONS Eligible Indian Tribes § 233.61 Determination of Tribal eligibility. An Indian Tribe may apply to the Regional Administrator for a determination that it meets the...

  3. 17 CFR 201.233 - Depositions upon oral examination.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Depositions upon oral... RULES OF PRACTICE Rules of Practice Initiation of Proceedings and Prehearing Rules § 201.233 Depositions... deposition shall make a written motion setting forth the reasons why such deposition should be taken...

  4. 17 CFR 201.233 - Depositions upon oral examination.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Depositions upon oral... RULES OF PRACTICE Rules of Practice Initiation of Proceedings and Prehearing Rules § 201.233 Depositions... deposition shall make a written motion setting forth the reasons why such deposition should be taken...

  5. 25 CFR 900.233 - When must an Indian tribe or tribal organization regulate its employees or subcontractors to...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... its employees or subcontractors to avoid a personal conflict of interest? 900.233 Section 900.233... HEALTH AND HUMAN SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Conflicts of Interest § 900.233 When must an Indian tribe or tribal organization regulate its employees or...

  6. 48 CFR 352.233-71 - Litigation and claims.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the action in good faith. The Government shall not be liable for the expense of defending any action... compensated by insurance which was required by law or regulation or by written direction of the Contracting... FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 352.233-71 Litigation...

  7. AP233: An Information Model for Systems Engineering

    NASA Technical Reports Server (NTRS)

    Siebes, Georg

    2009-01-01

    In today's world, information is abundant. We have no problems generating it. But we are challenged to find, organize, and exchange information. center dot A standardized model of information can help. Such a model nearly completed its development for Systems Engineering. It is referred to as AP233 (AP = Application Protocol).

  8. 45 CFR 233.24 - Retrospective budgeting; determining eligibility and computing the assistance payment in the...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Retrospective budgeting; determining eligibility and computing the assistance payment in the initial one or two months. 233.24 Section 233.24 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS...

  9. 45 CFR 233.26 - Retrospective budgeting; determining eligibility after the initial one or two months.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Retrospective budgeting; determining eligibility after the initial one or two months. 233.26 Section 233.26 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES...

  10. 45 CFR 233.24 - Retrospective budgeting; determining eligibility and computing the assistance payment in the...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Retrospective budgeting; determining eligibility and computing the assistance payment in the initial one or two months. 233.24 Section 233.24 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS...

  11. 45 CFR 233.26 - Retrospective budgeting; determining eligibility after the initial one or two months.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Retrospective budgeting; determining eligibility after the initial one or two months. 233.26 Section 233.26 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES...

  12. 49 CFR 238.233 - Interior fittings and surfaces.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... I Passenger Equipment § 238.233 Interior fittings and surfaces. (a) Each seat in a passenger car shall— (1) Be securely fastened to the car body so as to withstand an individually applied acceleration... deadweight of the seat or seats, if held in tandem; and (2) Have an attachment to the car body of an ultimate...

  13. 49 CFR 238.233 - Interior fittings and surfaces.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... I Passenger Equipment § 238.233 Interior fittings and surfaces. (a) Each seat in a passenger car shall— (1) Be securely fastened to the car body so as to withstand an individually applied acceleration... deadweight of the seat or seats, if held in tandem; and (2) Have an attachment to the car body of an ultimate...

  14. 49 CFR 238.233 - Interior fittings and surfaces.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... I Passenger Equipment § 238.233 Interior fittings and surfaces. (a) Each seat in a passenger car shall— (1) Be securely fastened to the car body so as to withstand an individually applied acceleration... deadweight of the seat or seats, if held in tandem; and (2) Have an attachment to the car body of an ultimate...

  15. 49 CFR 238.233 - Interior fittings and surfaces.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... I Passenger Equipment § 238.233 Interior fittings and surfaces. (a) Each seat in a passenger car shall— (1) Be securely fastened to the car body so as to withstand an individually applied acceleration... deadweight of the seat or seats, if held in tandem; and (2) Have an attachment to the car body of an ultimate...

  16. 33 CFR 110.233 - Prince William Sound, Alaska.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Prince William Sound, Alaska. 110... ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.233 Prince William Sound, Alaska. (a) The anchorage grounds. In Prince William Sound, Alaska, beginning at a point at latitude 60°40′00″ N., longitude 146°40...

  17. 33 CFR 110.233 - Prince William Sound, Alaska.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Prince William Sound, Alaska. 110... ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.233 Prince William Sound, Alaska. (a) The anchorage grounds. In Prince William Sound, Alaska, beginning at a point at latitude 60°40′00″ N., longitude 146°40...

  18. 33 CFR 110.233 - Prince William Sound, Alaska.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Prince William Sound, Alaska. 110... ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.233 Prince William Sound, Alaska. (a) The anchorage grounds. In Prince William Sound, Alaska, beginning at a point at latitude 60°40′00″ N., longitude 146°40...

  19. 33 CFR 110.233 - Prince William Sound, Alaska.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Prince William Sound, Alaska. 110... ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.233 Prince William Sound, Alaska. (a) The anchorage grounds. In Prince William Sound, Alaska, beginning at a point at latitude 60°40′00″ N., longitude 146°40...

  20. 33 CFR 110.233 - Prince William Sound, Alaska.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Prince William Sound, Alaska. 110... ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.233 Prince William Sound, Alaska. (a) The anchorage grounds. In Prince William Sound, Alaska, beginning at a point at latitude 60°40′00″ N., longitude 146°40...

  1. 34. SOUTHWEST CORNER OF BUILDING 233 (MISSILE ASSEMBLY SHOP) IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    34. SOUTHWEST CORNER OF BUILDING 233 (MISSILE ASSEMBLY SHOP) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  2. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based paint... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Lead-based paint activities...

  3. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based paint... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Lead-based paint activities...

  4. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based paint... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Lead-based paint activities...

  5. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based paint... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Lead-based paint activities...

  6. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based paint... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Lead-based paint activities...

  7. 35. EAST FRONT ELEVATION OF BUILDING 233 (MISSLE ASSEMBLY SHOP) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. EAST FRONT ELEVATION OF BUILDING 233 (MISSLE ASSEMBLY SHOP) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  8. 45 CFR 233.37 - How monthly reports are treated and what notices are required (AFDC).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true How monthly reports are treated and what notices are required (AFDC). 233.37 Section 233.37 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES COVERAGE AND...

  9. 36. CONTEXT VIEW LOOKING SOUTHWEST OF BUILDING 233 (MISSLE ASSEMBLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. CONTEXT VIEW LOOKING SOUTHWEST OF BUILDING 233 (MISSLE ASSEMBLY SHOP) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  10. 8 CFR 233.4 - Preinspection outside the United States.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Preinspection outside the United States... CONTRACTS WITH TRANSPORTATION LINES § 233.4 Preinspection outside the United States. (a) Form I-425 agreements. A transportation line bringing applicants for admission to the United States through...

  11. 8 CFR 233.4 - Preinspection outside the United States.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Preinspection outside the United States... CONTRACTS WITH TRANSPORTATION LINES § 233.4 Preinspection outside the United States. (a) Form I-425 agreements. A transportation line bringing applicants for admission to the United States through...

  12. 40 CFR 415.233 - Effluent limitations guidelines representing the degree of effluent reduction attainable by the...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... economically achievable (BAT). 415.233 Section 415.233 Protection of Environment ENVIRONMENTAL PROTECTION... economically achievable (BAT). Except as provided in 40 CFR 125.30 through 125.32, any existing point source... (BAT): The limitations for Fluoride(T), Chromium(T), and Nickel(T) are the same as specified in § 415...

  13. 40 CFR 415.233 - Effluent limitations guidelines representing the degree of effluent reduction attainable by the...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... economically achievable (BAT). 415.233 Section 415.233 Protection of Environment ENVIRONMENTAL PROTECTION... economically achievable (BAT). Except as provided in 40 CFR 125.30 through 125.32, any existing point source... (BAT): The limitations for Fluoride(T), Chromium(T), and Nickel(T) are the same as specified in § 415...

  14. 40 CFR 415.233 - Effluent limitations guidelines representing the degree of effluent reduction attainable by the...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... economically achievable (BAT). 415.233 Section 415.233 Protection of Environment ENVIRONMENTAL PROTECTION... economically achievable (BAT). Except as provided in 40 CFR 125.30 through 125.32, any existing point source... (BAT): The limitations for Fluoride(T), Chromium(T), and Nickel(T) are the same as specified in § 415...

  15. 40 CFR 86.233-94-86.234-94 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES Emission Regulations for 1994 and Later Model Year Gasoline-Fueled New Light-Duty Vehicles, New Light-Duty Trucks and New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures §§ 86.233-94—86.234-94 [Reserved] ...

  16. Breeding of 233U in the thorium-uranium fuel cycle in VVER reactors using heavy water

    NASA Astrophysics Data System (ADS)

    Marshalkin, V. E.; Povyshev, V. M.

    2015-12-01

    A method is proposed for achieving optimal neutron kinetics and efficient isotope transmutation in the 233U-232Th oxide fuel of water-moderated reactors with variable water composition (D2O, H2O) that ensures breeding of the 233U and 235U isotopes. The method is comparatively simple to implement.

  17. 45 CFR 233.25 - Retrospective budgeting; computing the assistance payment after the initial one or two months.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Retrospective budgeting; computing the assistance payment after the initial one or two months. 233.25 Section 233.25 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND...

  18. 45 CFR 233.25 - Retrospective budgeting; computing the assistance payment after the initial one or two months.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Retrospective budgeting; computing the assistance payment after the initial one or two months. 233.25 Section 233.25 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND...

  19. 45 CFR 233.106 - Denial of AFDC benefits to strikers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Section 233.106 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... refuse to seek or accept, employment. (2)(i) Provide for the denial of AFDC benefits to any family for...

  20. 49 CFR 212.233 - Apprentice highway-rail grade crossing inspector.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Apprentice highway-rail grade crossing inspector... Inspection Personnel § 212.233 Apprentice highway-rail grade crossing inspector. (a) An apprentice highway... Administrator for Safety leading to qualification as a highway-rail grade crossing inspector. The apprentice...

  1. 49 CFR 212.233 - Apprentice highway-rail grade crossing inspector.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Apprentice highway-rail grade crossing inspector... Inspection Personnel § 212.233 Apprentice highway-rail grade crossing inspector. (a) An apprentice highway... Administrator for Safety leading to qualification as a highway-rail grade crossing inspector. The apprentice...

  2. 49 CFR 212.233 - Apprentice highway-rail grade crossing inspector.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Apprentice highway-rail grade crossing inspector... Inspection Personnel § 212.233 Apprentice highway-rail grade crossing inspector. (a) An apprentice highway... Administrator for Safety leading to qualification as a highway-rail grade crossing inspector. The apprentice...

  3. 49 CFR 212.233 - Apprentice highway-rail grade crossing inspector.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Apprentice highway-rail grade crossing inspector... Inspection Personnel § 212.233 Apprentice highway-rail grade crossing inspector. (a) An apprentice highway... Administrator for Safety leading to qualification as a highway-rail grade crossing inspector. The apprentice...

  4. 49 CFR 212.233 - Apprentice highway-rail grade crossing inspector.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Apprentice highway-rail grade crossing inspector... Inspection Personnel § 212.233 Apprentice highway-rail grade crossing inspector. (a) An apprentice highway... Administrator for Safety leading to qualification as a highway-rail grade crossing inspector. The apprentice...

  5. Nuclear reactor for breeding U.sup.233

    DOEpatents

    Bohanan, Charles S.; Jones, David H.; Raab, Jr., Harry F.; Radkowsky, Alvin

    1976-01-01

    A light-water-cooled nuclear reactor capable of breeding U.sup.233 for use in a light-water breeder reactor includes physically separated regions containing U.sup.235 fissile material and U.sup.238 fertile material and Th.sup.232 fertile material and Pu.sup.239 fissile material, if available. Preferably the U.sup.235 fissile material and U.sup.238 fertile material are contained in longitudinally movable seed regions and the Pu.sup.239 fissile material and Th.sup.232 fertile material are contained in blanket regions surrounding the seed regions.

  6. 11. Architectural ELevations & Sections, 233S, U.S. Atomic Energy Commission, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Architectural ELevations & Sections, 233-S, U.S. Atomic Energy Commission, Hanford Atomic Products Operations, General Electric Company, Dwg. No. H-2-30465, 1956. - Reduction-Oxidation Complex, Plutonium Concentration Facility, 200 West Area, Richland, Benton County, WA

  7. 40 CFR 233.37 - Signatures on permit applications and reports.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Signatures on permit applications and... DUMPING 404 STATE PROGRAM REGULATIONS Program Operation § 233.37 Signatures on permit applications and... person designating the agent. In either case, the signature of the applicant or the agent will be...

  8. 27 CFR 31.233 - Mixing cocktails in advance of sale.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Mixing cocktails in... TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL ALCOHOL BEVERAGE DEALERS Miscellaneous § 31.233 Mixing cocktails in advance of sale. A retail liquor dealer shall not mix cocktails, or compound any alcoholic...

  9. 27 CFR 31.233 - Mixing cocktails in advance of sale.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Mixing cocktails in... TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL ALCOHOL BEVERAGE DEALERS Miscellaneous § 31.233 Mixing cocktails in advance of sale. A retail liquor dealer shall not mix cocktails, or compound any alcoholic...

  10. 27 CFR 31.233 - Mixing cocktails in advance of sale.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Mixing cocktails in... TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS ALCOHOL BEVERAGE DEALERS Miscellaneous § 31.233 Mixing cocktails in advance of sale. A retail liquor dealer shall not mix cocktails, or compound any alcoholic...

  11. 27 CFR 31.233 - Mixing cocktails in advance of sale.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Mixing cocktails in... TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS ALCOHOL BEVERAGE DEALERS Miscellaneous § 31.233 Mixing cocktails in advance of sale. A retail liquor dealer shall not mix cocktails, or compound any alcoholic...

  12. 233. Photocopy of drawing (1958 piping drawing by the Ralph ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    233. Photocopy of drawing (1958 piping drawing by the Ralph M. Parsons Company) PLAN FOR THE LIQUID OXYGEN CONTROL ROOM FOR THE LSB, SHEET P16 OF 36 - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  13. 16 CFR 233.2 - Retail price comparisons; comparable value comparisons.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 1 2012-01-01 2012-01-01 false Retail price comparisons; comparable value... GUIDES AGAINST DECEPTIVE PRICING § 233.2 Retail price comparisons; comparable value comparisons. (a.... Expressed another way, if a number of the principal retail outlets in the area are regularly selling Brand X...

  14. 16 CFR 233.2 - Retail price comparisons; comparable value comparisons.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Retail price comparisons; comparable value... GUIDES AGAINST DECEPTIVE PRICING § 233.2 Retail price comparisons; comparable value comparisons. (a.... Expressed another way, if a number of the principal retail outlets in the area are regularly selling Brand X...

  15. 16 CFR 233.2 - Retail price comparisons; comparable value comparisons.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Retail price comparisons; comparable value... GUIDES AGAINST DECEPTIVE PRICING § 233.2 Retail price comparisons; comparable value comparisons. (a.... Expressed another way, if a number of the principal retail outlets in the area are regularly selling Brand X...

  16. 16 CFR 233.2 - Retail price comparisons; comparable value comparisons.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 1 2013-01-01 2013-01-01 false Retail price comparisons; comparable value... GUIDES AGAINST DECEPTIVE PRICING § 233.2 Retail price comparisons; comparable value comparisons. (a.... Expressed another way, if a number of the principal retail outlets in the area are regularly selling Brand X...

  17. 5 CFR 532.233 - Preparation for full-scale wage surveys.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Preparation for full-scale wage surveys... REGULATIONS PREVAILING RATE SYSTEMS Prevailing Rate Determinations § 532.233 Preparation for full-scale wage... the local wage survey committee. (e) Selection and appointment of data collectors. (1) The local wage...

  18. 10. Architectural Door Details & Plot Plan, 233S, U.S. Atomic ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Architectural Door Details & Plot Plan, 233-S, U.S. Atomic Energy Commission, Hanford Atomic Products Operations, General Electric Company, Dwg. No. H-2-30469, 1956. - Reduction-Oxidation Complex, Plutonium Concentration Facility, 200 West Area, Richland, Benton County, WA

  19. Ruthenium-catalyzed regioselective allylic amination of 2,3,3-trifluoroallylic carbonates.

    PubMed

    Isobe, Shin-Ichi; Terasaki, Shou; Hanakawa, Taisyun; Mizuno, Shota; Kawatsura, Motoi

    2017-04-05

    We demonstrated the ruthenium-catalyzed allylic amination of 2,3,3-trifluoroallylic carbonates with several types of amines. The reactions proceeded with several types of amines, and succeeded in obtaining polyfluorinated terminal alkenes possessing branched allylic amines as a single regioisomer.

  20. 45 CFR 233.145 - Expiration of medical assistance programs under titles I, IV-A, X, XIV and XVI of the Social...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... titles I, IV-A, X, XIV and XVI of the Social Security Act. 233.145 Section 233.145 Public Welfare... FINANCIAL ASSISTANCE PROGRAMS § 233.145 Expiration of medical assistance programs under titles I, IV-A, X..., enacted July 30, 1965, no payment may be made to any State under title I, IV-A, X, XIV or XVI of the...

  1. 45 CFR 233.145 - Expiration of medical assistance programs under titles I, IV-A, X, XIV and XVI of the Social...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... titles I, IV-A, X, XIV and XVI of the Social Security Act. 233.145 Section 233.145 Public Welfare... FINANCIAL ASSISTANCE PROGRAMS § 233.145 Expiration of medical assistance programs under titles I, IV-A, X..., enacted July 30, 1965, no payment may be made to any State under title I, IV-A, X, XIV or XVI of the...

  2. 45 CFR 233.145 - Expiration of medical assistance programs under titles I, IV-A, X, XIV and XVI of the Social...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... titles I, IV-A, X, XIV and XVI of the Social Security Act. 233.145 Section 233.145 Public Welfare... FINANCIAL ASSISTANCE PROGRAMS § 233.145 Expiration of medical assistance programs under titles I, IV-A, X..., enacted July 30, 1965, no payment may be made to any State under title I, IV-A, X, XIV or XVI of the...

  3. 45 CFR 233.145 - Expiration of medical assistance programs under titles I, IV-A, X, XIV and XVI of the Social...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... titles I, IV-A, X, XIV and XVI of the Social Security Act. 233.145 Section 233.145 Public Welfare... FINANCIAL ASSISTANCE PROGRAMS § 233.145 Expiration of medical assistance programs under titles I, IV-A, X..., enacted July 30, 1965, no payment may be made to any State under title I, IV-A, X, XIV or XVI of the...

  4. 45 CFR 233.145 - Expiration of medical assistance programs under titles I, IV-A, X, XIV and XVI of the Social...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... titles I, IV-A, X, XIV and XVI of the Social Security Act. 233.145 Section 233.145 Public Welfare... FINANCIAL ASSISTANCE PROGRAMS § 233.145 Expiration of medical assistance programs under titles I, IV-A, X..., enacted July 30, 1965, no payment may be made to any State under title I, IV-A, X, XIV or XVI of the...

  5. Breeding of {sup 233}U in the thorium–uranium fuel cycle in VVER reactors using heavy water

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marshalkin, V. E., E-mail: marshalkin@vniief.ru; Povyshev, V. M.

    A method is proposed for achieving optimal neutron kinetics and efficient isotope transmutation in the {sup 233}U–{sup 232}Th oxide fuel of water-moderated reactors with variable water composition (D{sub 2}O, H{sub 2}O) that ensures breeding of the {sup 233}U and {sup 235}U isotopes. The method is comparatively simple to implement.

  6. 13. Elevations, 233S, U.S. Atomic Energy Commission, Hanford Works, General ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Elevations, 233-S, U.S. Atomic Energy Commission, Hanford Works, General Electric Company, Dwg. No. H-2-7203, 1956. - Reduction-Oxidation Complex, Plutonium Concentration Facility, 200 West Area, Richland, Benton County, WA

  7. 14 CFR 417.233 - Analysis for an unguided suborbital launch vehicle flown with a wind weighting safety system.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... vehicle flown with a wind weighting safety system. 417.233 Section 417.233 Aeronautics and Space... with a wind weighting safety system. For each launch of an unguided suborbital launch vehicle flown with a wind weighting safety system, in addition to the other requirements in this subpart outlined in...

  8. 14 CFR 417.233 - Analysis for an unguided suborbital launch vehicle flown with a wind weighting safety system.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... vehicle flown with a wind weighting safety system. 417.233 Section 417.233 Aeronautics and Space... with a wind weighting safety system. For each launch of an unguided suborbital launch vehicle flown with a wind weighting safety system, in addition to the other requirements in this subpart outlined in...

  9. 14 CFR 417.233 - Analysis for an unguided suborbital launch vehicle flown with a wind weighting safety system.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... vehicle flown with a wind weighting safety system. 417.233 Section 417.233 Aeronautics and Space... with a wind weighting safety system. For each launch of an unguided suborbital launch vehicle flown with a wind weighting safety system, in addition to the other requirements in this subpart outlined in...

  10. 14 CFR 417.233 - Analysis for an unguided suborbital launch vehicle flown with a wind weighting safety system.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... vehicle flown with a wind weighting safety system. 417.233 Section 417.233 Aeronautics and Space... with a wind weighting safety system. For each launch of an unguided suborbital launch vehicle flown with a wind weighting safety system, in addition to the other requirements in this subpart outlined in...

  11. 14 CFR 417.233 - Analysis for an unguided suborbital launch vehicle flown with a wind weighting safety system.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... vehicle flown with a wind weighting safety system. 417.233 Section 417.233 Aeronautics and Space... with a wind weighting safety system. For each launch of an unguided suborbital launch vehicle flown with a wind weighting safety system, in addition to the other requirements in this subpart outlined in...

  12. 1. West facade of Plutonium Concentration Facility (Building 233S), ReductionOxidation ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. West facade of Plutonium Concentration Facility (Building 233-S), Reduction-Oxidation Building (REDOX-202-S) to the right. Looking east. - Reduction-Oxidation Complex, Plutonium Concentration Facility, 200 West Area, Richland, Benton County, WA

  13. 12. Architectural Floor Plans, 233S, U.S. Atomic Energy Commission, Hanford ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Architectural Floor Plans, 233-S, U.S. Atomic Energy Commission, Hanford Atomic Products Operations, General Electric Company, Dwg. H-2-30464, 1956. - Reduction-Oxidation Complex, Plutonium Concentration Facility, 200 West Area, Richland, Benton County, WA

  14. 12 CFR 233.6 - Non-exclusive examples of policies and procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... THE FEDERAL RESERVE SYSTEM PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233... determination regarding the risk the commercial customer presents of engaging in an Internet gambling business... that the commercial customer presents a minimal risk of engaging in an Internet gambling business. (ii...

  15. 12 CFR 233.6 - Non-exclusive examples of policies and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... THE FEDERAL RESERVE SYSTEM PROHIBITION ON FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233... determination regarding the risk the commercial customer presents of engaging in an Internet gambling business... that the commercial customer presents a minimal risk of engaging in an Internet gambling business. (ii...

  16. ORNL experience and perspectives related to processing of thorium and 233U for nuclear fuel

    DOE PAGES

    Croff, Allen G.; Collins, Emory D.; Del Cul, G. D.; ...

    2016-05-01

    Thorium-based nuclear fuel cycles have received renewed attention in both research and public circles since about the year 2000. Much of the attention has been focused on nuclear fission energy production that utilizes thorium as a fertile element for producing fissionable 233U for recycle in thermal reactors, fast reactors, or externally driven systems. Here, lesser attention has been paid to other fuel cycle operations that are necessary for implementation of a sustainable thorium-based fuel cycle such as reprocessing and fabrication of recycle fuels containing 233U.

  17. 22 CFR Appendix A to Part 233 - Application for Compensation United States Agency for International Development Washington, DC 20523

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Agency for International Development Washington, DC 20523 A Appendix A to Part 233 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113-6-STANDARD TERMS AND CONDITIONS Pt. 233, App. A...

  18. 39 CFR 233.5 - Requesting financial records from a financial institution.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... address, and business phone number; (ii) The identity of the customer or customers to whom the records... 39 Postal Service 1 2012-07-01 2012-07-01 false Requesting financial records from a financial... INSPECTION SERVICE AUTHORITY § 233.5 Requesting financial records from a financial institution. (a...

  19. 39 CFR 233.5 - Requesting financial records from a financial institution.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... address, and business phone number; (ii) The identity of the customer or customers to whom the records... 39 Postal Service 1 2014-07-01 2014-07-01 false Requesting financial records from a financial... INSPECTION SERVICE AUTHORITY § 233.5 Requesting financial records from a financial institution. (a...

  20. 39 CFR 233.5 - Requesting financial records from a financial institution.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... address, and business phone number; (ii) The identity of the customer or customers to whom the records... 39 Postal Service 1 2013-07-01 2013-07-01 false Requesting financial records from a financial... INSPECTION SERVICE AUTHORITY § 233.5 Requesting financial records from a financial institution. (a...

  1. 39 CFR 233.5 - Requesting financial records from a financial institution.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... address, and business phone number; (ii) The identity of the customer or customers to whom the records... 39 Postal Service 1 2011-07-01 2011-07-01 false Requesting financial records from a financial... INSPECTION SERVICE AUTHORITY § 233.5 Requesting financial records from a financial institution. (a...

  2. 40 CFR 233.34 - Making a decision on the permit application.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Making a decision on the permit... DUMPING 404 STATE PROGRAM REGULATIONS Program Operation § 233.34 Making a decision on the permit... each application outlining his decision and rationale for his decision. The determination shall be...

  3. 18 CFR 367.2330 - Account 233, Notes payable to associate companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... POWER ACT AND NATURAL GAS ACT Balance Sheet Chart of Accounts Current and Accrued Liabilities § 367.2330... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Account 233, Notes payable to associate companies. 367.2330 Section 367.2330 Conservation of Power and Water Resources...

  4. Neutron-induced fission cross section measurement of 233U, 241Am and 243Am in the energy range 0.5 MeV En 20 MeV at n TOF at CERN

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Belloni, F.; Milazzo, P. M.; Calviani, M.

    2012-01-01

    Neutron-induced fission cross section measurements of 233U, 243Am and 241Am relative to 235U have been carried out at the neutron time-of-flight facility n TOF at CERN. A fast ionization chamber has been employed. All samples were located in the same detector; therefore the studied elements and the reference 235U target are subject to the same neutron beam.

  5. 43 CFR 2.33 - How will the Department notify you and the submitter of commercial or financial information when...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false How will the Department notify you and the submitter of commercial or financial information when it makes an appeal decision concerning such information? 2.33 Section 2.33 Public Lands: Interior Office of the Secretary of the Interior RECORDS AND TESTIMONY; FREEDOM OF INFORMATION ACT FOIA...

  6. 8 CFR 233.6 - Aliens entering Guam or the Commonwealth of the Northern Mariana Islands pursuant to Title VII of...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the Northern Mariana Islands pursuant to Title VII of Public Law 110-229, âConsolidated Natural Resources Act of 2008.â 233.6 Section 233.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY... of the Northern Mariana Islands pursuant to Title VII of Public Law 110-229, “Consolidated Natural...

  7. 8 CFR 233.6 - Aliens entering Guam or the Commonwealth of the Northern Mariana Islands pursuant to Title VII of...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... the Northern Mariana Islands pursuant to Title VII of Public Law 110-229, âConsolidated Natural Resources Act of 2008.â 233.6 Section 233.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY... of the Northern Mariana Islands pursuant to Title VII of Public Law 110-229, “Consolidated Natural...

  8. 8 CFR 233.6 - Aliens entering Guam or the Commonwealth of the Northern Mariana Islands pursuant to Title VII of...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the Northern Mariana Islands pursuant to Title VII of Public Law 110-229, âConsolidated Natural Resources Act of 2008.â 233.6 Section 233.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY... of the Northern Mariana Islands pursuant to Title VII of Public Law 110-229, “Consolidated Natural...

  9. 8 CFR 233.6 - Aliens entering Guam or the Commonwealth of the Northern Mariana Islands pursuant to Title VII of...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the Northern Mariana Islands pursuant to Title VII of Public Law 110-229, âConsolidated Natural Resources Act of 2008.â 233.6 Section 233.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY... of the Northern Mariana Islands pursuant to Title VII of Public Law 110-229, “Consolidated Natural...

  10. 8 CFR 233.6 - Aliens entering Guam or the Commonwealth of the Northern Mariana Islands pursuant to Title VII of...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the Northern Mariana Islands pursuant to Title VII of Public Law 110-229, âConsolidated Natural Resources Act of 2008.â 233.6 Section 233.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY... of the Northern Mariana Islands pursuant to Title VII of Public Law 110-229, “Consolidated Natural...

  11. 29 CFR 779.233 - Independent contractors performing work “for” an enterprise.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Apply; Enterprise Coverage Leased Departments, Franchise and Other Business Arrangements § 779.233... section 3(r) has reference to an independent business which performs services for other businesses as an established part of its own business activities. The term “independent contractor” as used in 3(r) thus has...

  12. 25 CFR 162.233 - Who will own the improvements made under an agricultural lease?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... WATER LEASES AND PERMITS Agricultural Leases Lease Requirements § 162.233 Who will own the improvements... landowners choose not to exercise this option, we will take appropriate enforcement action to ensure removal...

  13. 25 CFR 162.233 - Who will own the improvements made under an agricultural lease?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... WATER LEASES AND PERMITS Agricultural Leases Lease Requirements § 162.233 Who will own the improvements... landowners choose not to exercise this option, we will take appropriate enforcement action to ensure removal...

  14. 25 CFR 162.233 - Who will own the improvements made under an agricultural lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... WATER LEASES AND PERMITS Agricultural Leases Lease Requirements § 162.233 Who will own the improvements... landowners choose not to exercise this option, we will take appropriate enforcement action to ensure removal...

  15. 25 CFR 162.233 - Who will own the improvements made under an agricultural lease?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... WATER LEASES AND PERMITS Agricultural Leases Lease Requirements § 162.233 Who will own the improvements... landowners choose not to exercise this option, we will take appropriate enforcement action to ensure removal...

  16. 25 CFR 162.233 - Who will own the improvements made under an agricultural lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... WATER LEASES AND PERMITS Agricultural Leases Lease Requirements § 162.233 Who will own the improvements... landowners choose not to exercise this option, we will take appropriate enforcement action to ensure removal...

  17. 48 CFR 52.233-4 - Applicable Law for Breach of Contract Claim.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Provisions and Clauses 52.233-4 Applicable Law for Breach of Contract Claim. As prescribed in 33.215(b), insert the following clause: Applicable Law for Breach of Contract Claim (OCT 2004) United States law... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Applicable Law for Breach...

  18. 20 CFR 702.233 - Penalty for failure to pay without an award.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Penalty for failure to pay without an award... Procedures Noncontroverted Claims § 702.233 Penalty for failure to pay without an award. If any installment of compensation payable without an award is not paid within 14 days after it becomes due, there shall...

  19. Efficient Low-Voltage Operation of a CW Gyrotron Oscillator at 233 GHz.

    PubMed

    Hornstein, Melissa K; Bajaj, Vikram S; Griffin, Robert G; Temkin, Richard J

    2007-02-01

    The gyrotron oscillator is a source of high average power millimeter-wave through terahertz radiation. In this paper, we report low beam power and high-efficiency operation of a tunable gyrotron oscillator at 233 GHz. The low-voltage operating mode provides a path to further miniaturization of the gyrotron through reduction in the size of the electron gun, power supply, collector, and cooling system, which will benefit industrial and scientific applications requiring portability. Detailed studies of low-voltage operation in the TE(2) (,) (3) (,) (1) mode reveal that the mode can be excited with less than 7 W of beam power at 3.5 kV. During CW operation with 3.5-kV beam voltage and 50-mA beam current, the gyrotron generates 12 W of RF power at 233.2 GHz. The EGUN electron optics code describes the low-voltage operation of the electron gun. Using gun-operating parameters derived from EGUN simulations, we show that a linear theory adequately predicts the low experimental starting currents.

  20. Efficient Low-Voltage Operation of a CW Gyrotron Oscillator at 233 GHz

    PubMed Central

    Hornstein, Melissa K.; Bajaj, Vikram S.; Griffin, Robert G.; Temkin, Richard J.

    2007-01-01

    The gyrotron oscillator is a source of high average power millimeter-wave through terahertz radiation. In this paper, we report low beam power and high-efficiency operation of a tunable gyrotron oscillator at 233 GHz. The low-voltage operating mode provides a path to further miniaturization of the gyrotron through reduction in the size of the electron gun, power supply, collector, and cooling system, which will benefit industrial and scientific applications requiring portability. Detailed studies of low-voltage operation in the TE2,3,1 mode reveal that the mode can be excited with less than 7 W of beam power at 3.5 kV. During CW operation with 3.5-kV beam voltage and 50-mA beam current, the gyrotron generates 12 W of RF power at 233.2 GHz. The EGUN electron optics code describes the low-voltage operation of the electron gun. Using gun-operating parameters derived from EGUN simulations, we show that a linear theory adequately predicts the low experimental starting currents. PMID:17687412

  1. Isolation and characterization of racemase from Ensifer sp. 23-3 that acts on α-aminolactams and α-amino acid amides.

    PubMed

    Matsui, Daisuke; Fuhshuku, Ken-Ichi; Nagamori, Shingo; Takata, Momoko; Asano, Yasuhisa

    2017-11-01

    Limited information is available on α-amino-ε-caprolactam (ACL) racemase (ACLR), a pyridoxal 5'-phosphate-dependent enzyme that acts on ACL and α-amino acid amides. In the present study, eight bacterial strains with the ability to racemize α-amino-ε-caprolactam were isolated and one of them was identified as Ensifer sp. strain 23-3. The gene for ACLR from Ensifer sp. 23-3 was cloned and expressed in Escherichia coli. The recombinant ACLR was then purified to homogeneity from the E. coli transformant harboring the ACLR gene from Ensifer sp. 23-3, and its properties were characterized. This enzyme acted not only on ACL but also on α-amino-δ-valerolactam, α-amino-ω-octalactam, α-aminobutyric acid amide, and alanine amide.

  2. Comparison of Hansen--Roach and ENDF/B-IV cross sections for $sup 233$U criticality calculations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McNeany, S. R.; Jenkins, J. D.

    A comparison is made between criticality calculations performed using ENDF/B-IV cross sections and the 16-group Hansen-- Roach library at ORNL. The area investigated is homogeneous systems of highly enriched $sup 233$U in simple geometries. Calculations are compared with experimental data for a wide range of H/$sup 233$U ratios. Results show that calculations of k/sub eff/ made with the Hansen--Roach cross sections agree within 1.5 percent for the experiments considered. Results using ENDF/B-IV cross sections were in good agreement for well-thermalized systems, but discrepancies up to 7 percent in k/sub eff/ were observed in fast and epithermal systems. (auth)

  3. 16 CFR 233.4 - Bargain offers based upon the purchase of other merchandise.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Bargain offers based upon the purchase of... PRACTICE RULES GUIDES AGAINST DECEPTIVE PRICING § 233.4 Bargain offers based upon the purchase of other... given a customer on the condition that he purchase a particular article at the price usually offered by...

  4. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eppich, Gary R.; Williams, Ross W.; Gaffney, Amy M.

    Here, age dating of nuclear material can provide insight into source and suspected use in nuclear forensic investigations. We report here a method for the determination of the date of most recent chemical purification for uranium materials using the 235U- 231Pa chronometer. Protactinium is separated from uranium and neptunium matrices using anion exchange resin, followed by sorption of Pa to an SiO 2 medium. The concentration of 231Pa is measured by isotope dilution mass spectrometry using 233Pa spikes prepared from an aliquot of 237Np and calibrated in-house using the rock standard Table Mountain Latite and the uranium isotopic standard U100.more » Combined uncertainties of age dates using this method are 1.5 to 3.5 %, an improvement over alpha spectrometry measurement methods. Model ages of five uranium standard reference materials are presented; all standards have concordant 235U- 231Pa and 234U- 230Th model ages.« less

  5. ECDSA B-233 with Precomputation 1.0 Beta Version

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Draelos, Timothy; Schroeppel, Richard; Schoeneman, Barry

    2009-12-11

    This software, written in C, performs two functions: 1) the generation of digital signatures using ECDSA with the B-233 curve and a table of precomputed values, and 2) the generation and encryption of a table of precomputed values to support the generation of many digital signatures. The computationally expensive operations of ECDSA signature generation are precomputed, stored in a table, and protected with AES encryption. This allows digital signatures to be generated in low-power, computationally-constrained environments, such as are often found in non-proliferation monitoring applications. The encrypted, precomputed table and digital signature generation software are used to provide public keymore » data authentication for sensor data. When digital data is presented for signing, a set of values from the table is decrypted and used to generate an ECDSA digital signatureThis software, written in C, performs two functions: 1) the generation of digital signatures using ECDSA with the B-233 curve and a table of precomputed values, and 2) the generation and encryption of a table of precomputed values to support the generation of many digital signatures. The computationally expensive operations of ECDSA signature generation are precomputed, stored in a table, and protected with AES encryption. This allows digital signatures to be generated in low-power, computationally-constrained environments, such as are often found in non-proliferation monitoring applications. The encrypted, precomputed table and digital signature generation software are used to provide public key data authentication for sensor data. When digital data is presented for signing, a set of values from the table is decrypted and used to generate an ECDSA digital signature« less

  6. SCALE TSUNAMI Analysis of Critical Experiments for Validation of 233U Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mueller, Don; Rearden, Bradley T

    2009-01-01

    Oak Ridge National Laboratory (ORNL) staff used the SCALE TSUNAMI tools to provide a demonstration evaluation of critical experiments considered for use in validation of current and anticipated operations involving {sup 233}U at the Radiochemical Development Facility (RDF). This work was reported in ORNL/TM-2008/196 issued in January 2009. This paper presents the analysis of two representative safety analysis models provided by RDF staff.

  7. 49 CFR 23.3 - What do the terms used in this part mean?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... means a commercial service airport that has a number of passenger boardings equal to at least 0.25... distinctions or classifications on the basis of race or gender. Secretary means the Secretary of Transportation... 49 Transportation 1 2012-10-01 2012-10-01 false What do the terms used in this part mean? 23.3...

  8. 49 CFR 23.3 - What do the terms used in this part mean?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... means a commercial service airport that has a number of passenger boardings equal to at least 0.25... distinctions or classifications on the basis of race or gender. Secretary means the Secretary of Transportation... 49 Transportation 1 2014-10-01 2014-10-01 false What do the terms used in this part mean? 23.3...

  9. 39 CFR 233.11 - Mail reasonably suspected of being dangerous to persons or property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Mail reasonably suspected of being dangerous to... ADMINISTRATION INSPECTION SERVICE AUTHORITY § 233.11 Mail reasonably suspected of being dangerous to persons or... other dangerous contents in the mails. The screening must be within the limits of this section and...

  10. 39 CFR 233.11 - Mail reasonably suspected of being dangerous to persons or property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Mail reasonably suspected of being dangerous to... ADMINISTRATION INSPECTION SERVICE AUTHORITY § 233.11 Mail reasonably suspected of being dangerous to persons or... other dangerous contents in the mails. The screening must be within the limits of this section and...

  11. 39 CFR 233.11 - Mail reasonably suspected of being dangerous to persons or property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Mail reasonably suspected of being dangerous to... ADMINISTRATION INSPECTION SERVICE AUTHORITY § 233.11 Mail reasonably suspected of being dangerous to persons or... other dangerous contents in the mails. The screening must be within the limits of this section and...

  12. 39 CFR 233.11 - Mail reasonably suspected of being dangerous to persons or property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 39 Postal Service 1 2013-07-01 2013-07-01 false Mail reasonably suspected of being dangerous to... ADMINISTRATION INSPECTION SERVICE AUTHORITY § 233.11 Mail reasonably suspected of being dangerous to persons or... other dangerous contents in the mails. The screening must be within the limits of this section and...

  13. Improving Students' Readiness for College: Homewood-Flossmoor High School, Illinois District 233. Case Study

    ERIC Educational Resources Information Center

    ACT, Inc., 2004

    2004-01-01

    This paper illustrates how Homewood-Flossmoor High School, Illinois District 233 addressed the decline in its student achievement results and improved college readiness among its students. This sharp decline caused school officials to stop and reevaluate what they were doing. A review of the facts led to a clear conclusion: "Rigorous…

  14. Induction of osteosarcoma and acute myeloid leukaemia in CBA/H mice by the alpha-emitting nuclides, uranium-233, plutonium-239 and amercium-241.

    PubMed

    Ellender, M; Harrison, J D; Pottinger, H; Thomas, J M

    2001-01-01

    To compare tumour induction in CBA/H mice, principally osteosarcoma and acute myeloid leukaemia, resulting from exposure to the alpha-emitting nuclides, uranium-233, plutonium-239 and americium-241, and to relate differences between the three nuclides to the pattern of dose delivery within tissues. Each nuclide was administered intraperitoneally in citrate solution to three groups of adult male CBA/H mice at levels of activity which gave estimated life-time average skeletal doses of about 0.25-0.3 Gy, 0.5-1 Gy and 1-2 Gy. Animals were carefully monitored and sacrificed as soon as they showed signs of ill health; tumours were identified by standard histopathological techniques. Statistical modelling by Cox regression showed that, considering all three nuclides together, there was a highly significant increase in risk of death from osteosarcoma or myeloid leukaemia with increasing dose rate. For osteosarcoma, the effect was significantly greater for 239Pu than 241Am, while separate analysis for 233U showed no significant increase with increasing dose rate. For example, the increase in relative risk of death from osteosarcoma for an increase in life-time average dose rate to bone of 1 mGyd(-1) was 4.2 (2.7-6.5) for 239Pu, 2.3 (1.4-3.4) for 241Am and 1.1 (0.4-3.1) for 233U. For myeloid leukaemia, there was no significant difference between 239Pu and 241Am in the effect of dose rate. The increase in relative risk from myeloid leukaemia for an increase in average dose rate of 1 mGyd(-1) was 1.8 (1.1-2.8) for 239Pu, 2.0 (1.4-2.9) for 241Am and 1.5 (0.8-2.7) for 233U. Significant increases in renal and hepatic carcinomas were also recorded in animals exposed to 233U and 241Am, respectively. Studies of the distribution of the nuclides within the skeleton, published separately, have shown differences in their retention in individual bones and within bone. The proportions of decays occurring near to endosteal bone surfaces and throughout bone marrow were in the order: 239Pu

  15. RECOVERY OF URANIUM BY SECONDARY XANTHATE COMPLEXING

    DOEpatents

    Neville, O.K.

    1959-09-01

    A method is described for separating and recovering uranium values contained in an acidic aqueous solution together with thorium or protactinium values. In accordance with the invention, the acidic solution containing uranium in the uranyl form is contacted with an organic xanthate. The xanthate forms a urano-xanthate complex but is substantially non-reactive with thorium and protactinium. The urano-xanthate complex is recovered by organic solvent extraction.

  16. 45 CFR 233.107 - Restriction in payment to households headed by a minor parent.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Restriction in payment to households headed by a... Restriction in payment to households headed by a minor parent. (a) State plan requirements. A State in its... for assistance paid under the State plan to a pregnant woman as provided in § 233.90(c)(2)(iv) of this...

  17. Effect of graphite target power density on tribological properties of graphite-like carbon films

    NASA Astrophysics Data System (ADS)

    Dong, Dan; Jiang, Bailing; Li, Hongtao; Du, Yuzhou; Yang, Chao

    2018-05-01

    In order to improve the tribological performance, a series of graphite-like carbon (GLC) films with different graphite target power densities were prepared by magnetron sputtering. The valence bond and microstructure of films were characterized by AFM, TEM, XPS and Raman spectra. The variation of mechanical and tribological properties with graphite target power density was analyzed. The results showed that with the increase of graphite target power density, the deposition rate and the ratio of sp2 bond increased obviously. The hardness firstly increased and then decreased with the increase of graphite target power density, whilst the friction coefficient and the specific wear rate increased slightly after a decrease with the increasing graphite target power density. The friction coefficient and the specific wear rate were the lowest when the graphite target power density was 23.3 W/cm2.

  18. Determination of the half-life of the ground state of {sup 229}Th by using {sup 232}U and {sup 233}U decay series

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kikunaga, H.; Nishina Center for Accelerator-Based Science, RIKEN, Wako, Saitama 351-0198; Suzuki, T.

    2011-07-15

    The half-life of the ground state of {sup 229}Th ({sup 229}Th{sup g}) has become an important factor in nuclear technology, for example, in the geological disposal of nuclear spent fuel. However, the values reported in two previous studies are not in agreement. This study reevaluates the half-life of {sup 229}Th{sup g} by using a simple and reliable method. The {sup 232}U/{sup 233}U activity ratio of a {sup 232,233}U sample was measured by high-resolution {alpha}-particle spectrometry. Next, the {sup 228}Th/{sup 229}Th{sup g} activity ratio of the Th sample, which was grown from the {sup 232,233}U sample, was also measured. The half-lifemore » of {sup 229}Th{sup g} was calculated from these activity ratios, the growth time, and the half-lives of {sup 232}U, {sup 233}U, and {sup 228}Th. From the results of these five measurements, the half-life of {sup 229}Th{sup g} is determined to be 7932 {+-} 55 yr at a confidence level of 2{sigma}.« less

  19. Draft genome sequence of the D-Xylose-Fermenting yeast Spathaspora xylofermentans UFMG-HMD23.3

    USDA-ARS?s Scientific Manuscript database

    Here, we report the draft genome sequence of the yeast Spathaspora xylofermentans UFMG-HMD23.3 (CBMAI 1427=CBS 12681), a D-xylose fermenting yeast isolated from the Amazonian forest. The genome consists of 298 contigs, with a total size of 15.1 Mb, including the mitochondrial genome, and 5,948 predi...

  20. Qualification and initial characterization of a high-purity 233U spike for use in uranium analyses

    DOE PAGES

    Mathew, K. J.; Canaan, R. D.; Hexel, C.; ...

    2015-08-20

    Several high-purity 233U items potentially useful as isotope dilution mass spectrometry standards for safeguards, non-proliferation, and nuclear forensics measurements are identified and rescued from downblending. By preserving the supply of 233U materials of different pedigree for use as source materials for certified reference materials (CRMs), it is ensured that the safeguards community has high quality uranium isotopic standards required for calibration of the analytical instruments. One of the items identified as a source material for a high-purity CRM is characterized for the uranium isotope-amount ratios using thermal ionization mass spectrometry (TIMS). Additional verification measurements on this material using quadrupole inductivelymore » coupled plasma mass spectrometry (ICPMS) are also performed. As a result, the comparison of the ICPMS uranium isotope-amount ratios with the TIMS data, with much smaller uncertainties, validated the ICPMS measurement practices. ICPMS is proposed for the initial screening of the purity of items in the rescue campaign.« less

  1. 30 CFR 250.233 - What decisions will MMS make on the EP and within what timeframe?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Plans and Information Review and Decision Process for the Ep § 250.233 What..., including those to provide monitoring information. (2) Require you to modify your proposed EP The Regional...

  2. Actinide targets for fundamental research in nuclear physics

    NASA Astrophysics Data System (ADS)

    Eberhardt, K.; Düllmann, Ch. E.; Haas, R.; Mokry, Ch.; Runke, J.; Thörle-Pospiech, P.; Trautmann, N.

    2018-05-01

    Thin actinide layers deposited on various substrates are widely used as calibration sources in nuclear spectroscopy. Other applications include fundamental research in nuclear chemistry and -physics, e.g., the chemical and physical properties of super-heavy elements (SHE, Z > 103) or nuclear reaction studies with heavy ions. For the design of future nuclear reactors like fast-fission reactors and accelerator-driven systems for transmutation of nuclear waste, precise data for neutron absorption as well as neutron-induced fission cross section data for 242Pu with neutrons of different energies are of particular importance, requiring suitable Pu-targets. Another application includes studies of nuclear transitions in 229Th harvested as α-decay recoil product from a thin layer of its 233U precursor. For this, a thin and very smooth layer of 233U is used. We report here on the production of actinide layers mostly obtained by Molecular Plating (MP). MP is currently the only fabrication method in cases where the desired actinide material is available only in very limited amounts or possesses a high specific activity. Here, deposition is performed from organic solution applying a current density of 1-2 mA/cm2. Under these conditions target thicknesses of 500-1000 μg/cm2 are possible applying a single deposition step with deposition yields approaching 100 %. For yield determination α-particle spectroscopy, γ-spectroscopy and Neutron Activation Analysis is routinely used. Layer homogeneity is checked with Radiographic Imaging. As an alternative technique to MP the production of thin lanthanide and actinide layers by the so-called "Drop on Demand"-technique applied e.g., in ink-jet printing is currently under investigation.

  3. Water Ingress Testing of the Turbula Jar and U-233 Lead Pig Containers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reeves, Kirk Patrick; Karns, Tristan; Smith, Paul Herrick

    Understanding the water ingress behavior of containers used at the TA-55 Plutonium Facility has significant implications for criticality safety. The purpose of this report is to document the water ingress behavior of the Turbula Jar with Bakelite lid and Viton gaskets (Turbula Jar) used in oxide blending operations and the U-233 lead pig container used to store and transport U-233 material. The technical basis for water resistant containers at TA-55 is described in LA-UR-15-22781, “Water Resistant Container Technical Basis Document for the TA-55 Criticality Safety Program.” Testing of the water ingress behavior of various containers is described in LA-CP-13-00695, “Watermore » Penetration Tests on the Filters of Hagan and SAVY Containers,” LA-UR-15-23121, “Water Ingress into Crimped Convenience Containers under Flooding Conditions,” and in LA-UR- 16-2411, “Water Ingress Testing for TA-55 Containers.” Water ingress criteria are defined in TA55-AP-522 “TA-55 Criticality Safety Program”, and in PA-RD-01009 “TA55 Criticality Safety Requirements.” The water ingress criteria for submersion is no more than 50 ml of water ingress at a 6” water column height for a period of 2 hours.« less

  4. 45 CFR 233.35 - Computing the assistance payment under retrospective budgeting after the initial one or two...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Computing the assistance payment under... FINANCIAL ASSISTANCE PROGRAMS § 233.35 Computing the assistance payment under retrospective budgeting after... shall be computed retrospectively, i.e., shall be based on income and other relevant circumstances in...

  5. 45 CFR 233.34 - Computing the assistance payment in the initial one or two months (AFDC).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Computing the assistance payment in the initial... § 233.34 Computing the assistance payment in the initial one or two months (AFDC). A State shall compute...) If the initial month is computed prospectively as in paragraph (a) of this section, the second month...

  6. Fiscal Year 2008 Phased Construction Completion Report for EU Z2-33 in Zone 2, East Tennessee Technology Park, Oak Ridge, Tennessee

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bechtel Jacobs

    The Record of Decision for Soil, Buried Waste, and Subsurface Structure Actions in Zone 2, East Tennessee Technology Park, Oak Ridge, Tennessee (DOE/OR/01-2161&D2) (Zone 2 ROD) acknowledged that most of the 800 acres in Zone 2 were contaminated, but that sufficient data to confirm the levels of contamination were lacking. The Zone 2 ROD further specified that a sampling strategy for filling the data gaps would be developed. The Remedial Design Report/Remedial Action Work Plan for Zone 2 Soils, Slabs, and Subsurface Structures, East Tennessee Technology Park, Oak Ridge, Tennessee (DOE/OR/01-2224&D3) (Zone 2 RDR/RAWP) defined the sampling strategy as themore » Dynamic Verification Strategy (DVS), generally following the approach used for characterization of the Zone 1 exposure units (EUs). The Zone 2 ROD divided the Zone 2 area into seven geographic areas and 44 EUs. To facilitate the data quality objectives (DQOs) of the DVS process, the Zone 2 RDR/RAWP regrouped the 44 EUs into 12 DQO scoping EU groups. These groups facilitated the DQO process by placing similar facilities and their support facilities together and allowing identification of data gaps. The EU groups were no longer pertinent after DQO planning was completed and characterization was conducted as areas became accessible. As the opportunity to complete characterization became available, the planned DVS program and remedial actions (RAs) were completed for EU Z2-33. Remedial action was also performed at two additional areas in adjacent EU Z2-42 because of their close proximity and similar nature to a small surface soil RA in EU Z2-33. Remedial actions for building slabs performed in EU Z2-33 during fiscal year (FY) 2007 were reported in the Fiscal Year 2007 Phased Construction Completion Report for the Zone 2 Soils, Slabs, and Subsurface Structures at East Tennessee Technology Park, Oak Ridge, Tennessee (DOE/OR/01-2723&D1). Recommended RAs for EU Z2-42 were described in the Fiscal Year 2006 Phased

  7. Th/U-233 multi-recycle in pressurized water reactors : feasibility study of multiple homogeneous and heterogeneous assembly designs.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yun, D.; Taiwo, T. A.; Kim, T. K.

    2010-10-01

    The use of thorium in current or advanced light water reactors (LWRs) has been of interest in recent years. These interests have been associated with the need to increase nuclear fuel resources and the perceived non-proliferation advantages of the utilization of thorium in the fuel cycle. Various options have been considered for the use of thorium in the LWR fuel cycle. The possibility for thorium utilization in a multi-recycle system has also been considered in past literature, primarily because of the potential for near breeders with Th/U-233 in the thermal energy range. The objective of this study is to evaluatemore » the potential of Th/U-233 fuel multi-recycle in current LWRs, focusing on pressurized water reactors (PWRs). Approaches for sustainable multi-recycle without the need for external fissile material makeup have been investigated. The intent is to obtain a design that allows existing PWRs to be used with minimal modifications.« less

  8. Desorption Kinetics of H2O from Cab-O-Sil-M-7D and Hi-Sil-233 Silica Particles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dinh, L.; Balooch, M.; LeMay, J.D.

    2000-01-26

    Temperature programmed desorption (TPD) was performed at temperatures up to 850K on Cab-O-Sil-M-7D and Hi-Sil-233 silica particles. Physisorbed water molecules on both types of silica had activation energies in the range of 9-14.5 kcal/mol. However, the activation energies of desorption for chemisorbed water varied from {approx} 19 kcal/mol to > 59 kcal/mol for Cab-O-Sil-M-7D, and {approx} 23-37 kcal/mol for Hi-Sil-233. Our results suggest that physisorbed water can be effectively pumped away at room temperature (or preferably at 320 K) in a matter of hours. Chemisorbed water with high activation energies of desorption (>30 kcal/mol) will not escape the silica surfacesmore » in 100 years even at 320 K, while a significant amount of the chemisorbed water with medium activation energies (19-26 kcal/mol) will leave the silica surfaces in that time span. Most of the chemisorbed water with activation energies < 30 kcal/mol can be pumped away in a matter of days in a good vacuum environment at 500 K. We had previously measured about 0.1-0.4 wt. % of water in M9787 polysiloxane formulations containing {approx} 21% Cab-O-Sil-M-7D and {approx} 4% Hi-Sil-233. Comparing present results with these formulations, we conclude that absorbed H{sub 2}O and Si-OH bonds on the silica surfaces are the major contributors to water outgassing from M97 series silicones.« less

  9. An in-depth analysis identifies two new independent signals in 11q23.3 associated with vitiligo in the Chinese Han population.

    PubMed

    Zhao, Suli; Fang, Fang; Tang, Xianfa; Dou, Jinfa; Wang, Wenjun; Zheng, Xiaodong; Sun, Liangdan; Zhang, Anping

    2017-10-01

    Vitiligo is an autoimmune disease, characterized by progressive loss of skin pigmentation, which is caused by the interactions of multiple factors, such as heredity, immunity and environment. Recently, a single nucleotide polymorphism (SNP) rs638893 at 11q23.3 region was identified as a risk factor for vitiligo in genome-wide association studies and multiple SNPs in this region have been associated with other autoimmune diseases. This study aims to identify additional susceptibility variants associated with vitiligo at 11q23.3 in the Chinese Han population. We selected and genotyped 26 SNPs at 11q23.3 in an independent cohort including 2924 cases and 4048 controls using the Sequenom MassArray iPLEX ® system. Bonferroni adjustment was used for multiple comparisons and P value <1.92×10 -3 (0.05/26) was considered statistically significant. The A allele of rs613791 and G allele of rs523604 located in CXCR5 were observed to be significantly associated with vitiligo (OR=1.21, 95% CI: 1.11-1.31, P=1.20×10 -5 ; OR=1.14, 95% CI: 1.07-1.23, P=1.90×10 -4 , respectively). The C allele of rs638893 (a previously reported one) located upstream of DDX6 was also significantly associated with vitiligo (OR=1.25, 95% CI: 1.12-1.38, P=3.04×10 -5 ). The genotypes distribution of 3 SNPs also showed significant differences between case and control (rs613791: P=7.00×10 -6 , rs523604: P=4.00×10 -3 , rs638893: P=1.20×10 -5 , respectively). The two newly identified SNPs (rs613791 and rs523604) showed independent associations with vitiligo by linkage disequilibrium analysis and conditional logistic regression. The study identified two new independent signals in the associated locus 11q23.3 for vitiligo. The presence of multiple independent variants emphasizes an important role of this region in disease susceptibility. Copyright © 2017 Japanese Society for Investigative Dermatology. Published by Elsevier B.V. All rights reserved.

  10. [Post-marketing safety surveillance of Diemailing Kudiezi injection: real world study in 30 233 cases].

    PubMed

    Liao, Xing; Yu, Dan-Dan; Xie, Yan-Ming; Zhang, Yun-Ling; He, Yan; Zhang, Yin; Liu, Yan; Yi, Dan-Hui; Wang, Yong-Yan

    2017-08-01

    This study was aimed to obtain the incidence of adverse drug reaction (ADR) of Diemailing Kudiezi injection, explore its characteristics, related risk factors and application in real world. A prospective single cohort study was conducted from 25 hospitals (including Chinese medicine hospitals and Western medicine hospitals) for 4 years. 30 233 consecutive inpatients using Diemailing Kudiezi injection were observed. Their general information was analyzed by using statistic frequency description. Association rules were used to analyze the correlation between comorbidities or drug combinations; the influential factors for ADRs were initially screened by using cross contingency method and Chi-square test, and then Group LASSAO method was used for further analysis. 54 patients with adverse drug events and 30 patients with ADRs were reported among 30 233 patients, with a total ADR incidence of 0.099%[95%CI (0.06%, 0.13%)]. There were 27 patients identified as the "general" ADR, one patients with "severe" ADR (anaphylactic shock) and two patients with new ADRs. ADR occurred most in 30 min after using Diemailing Kudiezi injection, in a total of 16 patients. The most ADRs were palpitation, vomiting, chills, pruritus and rash, 6 times for each symptom. Diemailing Kudiezi injection was well tolerated in the general population. The overall incidence of adverse reactions was rare, with high safety. However, the real incidence of ADRs may be underestimated in this study, and the blood samples were not obtained for the patients, so further mechanism studies shall be conducted. Copyright© by the Chinese Pharmaceutical Association.

  11. Crystal structure of the kinase domain of human protein tyrosine kinase 6 (PTK6) at 2.33 Å resolution.

    PubMed

    Thakur, Manish Kumar; Kumar, Amit; Birudukota, Swarnakumari; Swaminathan, Srinivasan; Tyagi, Rajiv; Gosu, Ramachandraiah

    2016-09-16

    Human Protein tyrosine kinase 6 (PTK6) (EC:2.7.10.2), also known as the breast tumor kinase (BRK), is an intracellular non-receptor Src-related tyrosine kinase expressed in a majority of human breast tumors and breast cancer cell lines, but its expression is low or completely absent in normal mammary glands. In the recent past, several studies have suggested that PTK6 is a potential therapeutic target in cancer. To understand its structural and functional properties, the PTK6 kinase domain (PTK6-KD) gene was cloned, overexpressed in a baculo-insect cell system, purified and crystallized at room temperature. X-ray diffraction data to 2.33 Å resolution was collected on a single PTK6-KD crystal, which belonged to the triclinic space group P1. The Matthews coefficient calculation suggested the presence of four protein molecules per asymmetric unit, with a solvent content of ∼50%.The structure has been solved by molecular replacement and crystal structure data submitted to the protein data bank under the accession number 5D7V. This is the first report of apo PTK6-KD structure crystallized in DFG-in and αC-helix-out conformation. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Rapid oxygenation of Earth's atmosphere 2.33 billion years ago.

    PubMed

    Luo, Genming; Ono, Shuhei; Beukes, Nicolas J; Wang, David T; Xie, Shucheng; Summons, Roger E

    2016-05-01

    Molecular oxygen (O2) is, and has been, a primary driver of biological evolution and shapes the contemporary landscape of Earth's biogeochemical cycles. Although "whiffs" of oxygen have been documented in the Archean atmosphere, substantial O2 did not accumulate irreversibly until the Early Paleoproterozoic, during what has been termed the Great Oxygenation Event (GOE). The timing of the GOE and the rate at which this oxygenation took place have been poorly constrained until now. We report the transition (that is, from being mass-independent to becoming mass-dependent) in multiple sulfur isotope signals of diagenetic pyrite in a continuous sedimentary sequence in three coeval drill cores in the Transvaal Supergroup, South Africa. These data precisely constrain the GOE to 2.33 billion years ago. The new data suggest that the oxygenation occurred rapidly-within 1 to 10 million years-and was followed by a slower rise in the ocean sulfate inventory. Our data indicate that a climate perturbation predated the GOE, whereas the relationships among GOE, "Snowball Earth" glaciation, and biogeochemical cycling will require further stratigraphic correlation supported with precise chronologies and paleolatitude reconstructions.

  13. Statistical analysis of measured free-space laser signal intensity over a 2.33 km optical path.

    PubMed

    Tunick, Arnold

    2007-10-17

    Experimental research is conducted to determine the characteristic behavior of high frequency laser signal intensity data collected over a 2.33 km optical path. Results focus mainly on calculated power spectra and frequency distributions. In addition, a model is developed to calculate optical turbulence intensity (C(n)/2) as a function of receiving and transmitting aperture diameter, log-amplitude variance, and path length. Initial comparisons of calculated to measured C(n)/2 data are favorable. It is anticipated that this kind of signal data analysis will benefit laser communication systems development and testing at the U.S. Army Research Laboratory (ARL) and elsewhere.

  14. Fission Product Yields of 233U, 235U, 238U and 239Pu in Fields of Thermal Neutrons, Fission Neutrons and 14.7-MeV Neutrons

    NASA Astrophysics Data System (ADS)

    Laurec, J.; Adam, A.; de Bruyne, T.; Bauge, E.; Granier, T.; Aupiais, J.; Bersillon, O.; Le Petit, G.; Authier, N.; Casoli, P.

    2010-12-01

    The yields of more than fifteen fission products have been carefully measured using radiochemical techniques, for 235U(n,f), 239Pu(n,f) in a thermal spectrum, for 233U(n,f), 235U(n,f), and 239Pu(n,f) reactions in a fission neutron spectrum, and for 233U(n,f), 235U(n,f), 238U(n,f), and 239Pu(n,f) for 14.7 MeV monoenergetic neutrons. Irradiations were performed at the EL3 reactor, at the Caliban and Prospero critical assemblies, and at the Lancelot electrostatic accelerator in CEA-Valduc. Fissions were counted in thin deposits using fission ionization chambers. The number of fission products of each species were measured by gamma spectrometry of co-located thick deposits.

  15. Nonrandom Intrafraction Target Motions and General Strategy for Correction of Spine Stereotactic Body Radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ma Lijun, E-mail: lijunma@radonc.ucsf.ed; Sahgal, Arjun; Hossain, Sabbir

    2009-11-15

    Purpose: To characterize nonrandom intrafraction target motions for spine stereotactic body radiotherapy and to develop a method of correction via image guidance. The dependence of target motions, as well as the effectiveness of the correction strategy for lesions of different locations within the spine, was analyzed. Methods and Materials: Intrafraction target motions for 64 targets in 64 patients treated with a total of 233 fractions were analyzed. Based on the target location, the cases were divided into three groups, i.e., cervical (n = 20 patients), thoracic (n = 20 patients), or lumbar-sacrum (n = 24 patients) lesions. For each case,more » time-lag autocorrelation analysis was performed for each degree of freedom of motion that included both translations (x, y, and z shifts) and rotations (roll, yaw, and pitch). A general correction strategy based on periodic interventions was derived to determine the time interval required between two adjacent interventions, to overcome the patient-specific target motions. Results: Nonrandom target motions were detected for 100% of cases regardless of target locations. Cervical spine targets were found to possess the highest incidence of nonrandom target motion compared with thoracic and lumbar-sacral lesions (p < 0.001). The average time needed to maintain the target motion to within 1 mm of translation or 1 deg. of rotational deviation was 5.5 min, 5.9 min, and 7.1 min for cervical, thoracic, and lumbar-sacrum locations, respectively (at 95% confidence level). Conclusions: A high incidence of nonrandom intrafraction target motions was found for spine stereotactic body radiotherapy treatments. Periodic interventions at approximately every 5 minutes or less were needed to overcome such motions.« less

  16. Rapid oxygenation of Earth’s atmosphere 2.33 billion years ago

    PubMed Central

    Luo, Genming; Ono, Shuhei; Beukes, Nicolas J.; Wang, David T.; Xie, Shucheng; Summons, Roger E.

    2016-01-01

    Molecular oxygen (O2) is, and has been, a primary driver of biological evolution and shapes the contemporary landscape of Earth’s biogeochemical cycles. Although “whiffs” of oxygen have been documented in the Archean atmosphere, substantial O2 did not accumulate irreversibly until the Early Paleoproterozoic, during what has been termed the Great Oxygenation Event (GOE). The timing of the GOE and the rate at which this oxygenation took place have been poorly constrained until now. We report the transition (that is, from being mass-independent to becoming mass-dependent) in multiple sulfur isotope signals of diagenetic pyrite in a continuous sedimentary sequence in three coeval drill cores in the Transvaal Supergroup, South Africa. These data precisely constrain the GOE to 2.33 billion years ago. The new data suggest that the oxygenation occurred rapidly—within 1 to 10 million years—and was followed by a slower rise in the ocean sulfate inventory. Our data indicate that a climate perturbation predated the GOE, whereas the relationships among GOE, “Snowball Earth” glaciation, and biogeochemical cycling will require further stratigraphic correlation supported with precise chronologies and paleolatitude reconstructions. PMID:27386544

  17. Incidence and management of leukopenia/neutropenia in 233 kidney transplant patients following single dose alemtuzumab induction.

    PubMed

    Smith, A; Couvillion, R; Zhang, R; Killackey, M; Buell, J; Lee, B; Saggi, B H; Paramesh, A S

    2014-12-01

    The purpose of this study was to determine the incidence and management strategies for post-transplant leukopenia/neutropenia in kidney recipients receiving alemtuzumab induction during the first year following transplantation. We prospectively identified 233 adult patients who underwent kidney transplantation with alemtuzumab induction at a single institution. The incidence and severity of leukopenia (white blood cell count [WBC] ≤2500/mm(3)) and neutropenia (absolute neutrophil count [ANC] ≤500/mm(3)) were evaluated at 1, 3, 6, and 12 months post-transplantation. We determined any association with cytomegalovirus (CMV) infection, graft rejection, and infections requiring hospitalization. We also reviewed interventions performed, including medication adjustments, treatment with granulocyte stimulating factor, and hospitalization. The combined incidence of either leukopenia or neutropenia was 47.5% (n = 114/233) with an average WBC nadir of 1700 ± 50/mm(3) at 131.0 ± 8.5 days and an average ANC nadir of 1500 ± 100/mm(3) at 130.4 ± 9.6 days. No significant difference in graft rejection, CMV infection, or infections requiring hospitalization was found in the leukopenia/neutropenia group vs the normal WBC group (P = .3). The most common intervention performed for leukopenia/neutropenia group was prophylactic medication adjustment. Six patients (5.2%) required a change in >1 medication. The majority of these patients also required granulocyte stimulating factor (61.5%; 32/52), with an average of 2.5 doses given. A total of 25 patients (21.9%) required hospitalization due to leukopenia/neutropenia with an average length of stay of 6 days. Kidney transplant patients receiving alemtuzumab induction required significant interventions due to leukopenia/neutropenia in the first year post-transplantation. These results suggest the need for additional studies aimed at defining the optimum management strategies of leukopenia/neutropenia in this population

  18. SEPARATION OF PROTACTINIUM FROM THORIUM IN NITRIC ACID SOLUTIONS BY SOLVENT EXTRACTION WITH TRIBUTYL PHOSPHATE OR BY ADSORPTION ON PULVERIZED UNFIRED VYCOR GLASS OR SILICA GEL

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moore, J.G.; Rainey, R.H.

    1963-04-01

    Two methods were investigated for the separation and recovery of Pa from short-decayed Th fuel in HNO/sub 3/ solutions. The Pa/sub 233/, Th, and U may be coextracted from highly acidic feed solutions with 30% tributyl phosphate, or the Pa may be preferentially adsorbed on pulverized unfired Vycor glass or silica gel. Major effort has been on the adsorption method. Adsorption experiments with tracer concentrations of Pa/sup 233/ in HNO/sub 3/ solutions showed distribution coefficient maxima for Pa of about 1000, 325, and 175 from 6 to 10 M HNO/sub 3/ for laboratory-prepared silica gel, unfired Vycor, and commercial silicamore » gel, respectively. Unfired Vycor, a commercial, leached borosilicate glass containing 96% SiO/sub 2/ and about 3% B/sub 2/O/sub 3/, was used for most of the studies. Fired Vycor glass adsorbed little or no Pa. The adsorption coefficient of Pa by unfired Vycor glass from HNO/sub 3/ solutions increased as the contact time increased or as the particle size of the glass decreased and was dependent on the concentration of salt or HNO/sub 3/ in the solution. The adsorbed Pa may be eluted with oxalic or tartaric acids. Although optimum conditions for column operations were not determined, decontamination factors of Pa from Th, U, Ru, Zr- Nb and total rare earths of 6x 10/sup 3/, 1.6 x 101,4 x 10/sup 3/, 3, and 5.8 x 10/sup 5/, respectively, were obtained in tracer experiments. Batch countercurrent scouting experiments with tracer Pa showed that about 90% of the Pa was extracted with the Th and U from 5 M HNO/sub 3/-1 M Al(NO/sub 3/)/sub 3/ solutions, with a decontamination factor of 70 from Ru and about 10/sup 5/ from rare earths. (P.C.H.)« less

  19. METHOD OF PREPARING PROTACTINIUM VALUES

    DOEpatents

    Katzin, L.I.; Larson, R.G.; Thompson, R.C.; Van Winkle, Q.

    1959-05-19

    Separation and purification from initial acid leaches of pitchblende of Pa is described. This supernatant acid solution is treated with alkali metal carbonates to precipitate Pa. Silica is removed from the precipitate by hydroxide treatment. The Pa residue is dissolved in HNO/sub 3/ and Pa is concentrated by cyclic precipitations with MnO/sub 2/. The last solution is hydrolyzed to precipitate Pa. The Pa precipitate contains Ti and Zr which are removed by ion exchange. (T.R.H.)

  20. The 234mPa Generator: Aspects of Milking the "234th Cow."

    ERIC Educational Resources Information Center

    Schwankner, Robert J.; And Others

    1985-01-01

    Uses the protactinium (Pa-234m) generator to illustrate the production of isotopes of short half-life for medical analysis. The principle of nuclide generators and suggested experiments (with procedures and typical results) are discussed. (JN)

  1. Importance of coccolithophore-associated organic biopolymers for fractionating particle-reactive radionuclides (234Th, 233Pa, 210Pb, 210Po, and 7Be) in the ocean

    NASA Astrophysics Data System (ADS)

    Lin, Peng; Xu, Chen; Zhang, Saijin; Sun, Luni; Schwehr, Kathleen A.; Bretherton, Laura; Quigg, Antonietta; Santschi, Peter H.

    2017-08-01

    Laboratory incubation experiments using the coccolithophore Emiliania huxleyi were conducted in the presence of 234Th, 233Pa, 210Pb, 210Po, and 7Be to differentiate radionuclide uptake to the CaCO3 coccosphere from coccolithophore-associated biopolymers. The coccosphere (biogenic calcite exterior and its associated biopolymers), extracellular (nonattached and attached exopolymeric substances), and intracellular (sodium-dodecyl-sulfate extractable and Fe-Mn-associated metabolites) fractions were obtained by sequentially extraction after E. huxleyi reached its stationary growth phase. Radionuclide partitioning and the composition of different organic compound classes, including proteins, total carbohydrates (TCHO), and uronic acids (URA), were assessed. 210Po was closely associated with the more hydrophobic biopolymers (high protein/TCHO ratio, e.g., in attached exopolymeric substances), while 234Th and 233Pa showed similar partitioning behavior with most activity being distributed in URA-enriched, nonattached exopolymeric substances and intracellular biopolymers. 234Th and 233Pa were nearly undetectable in the coccosphere, with a minor abundance of organic components in the associated biopolymers. These findings provide solid evidence that biogenic calcite is not the actual main carrier phase for Th and Pa isotopes in the ocean. In contrast, both 210Pb and 7Be were found to be mostly concentrated in the CaCO3 coccosphere, likely substituting for Ca2+ during coccolith formation. Our results demonstrate that even small cells (E. huxleyi) can play an important role in the scavenging and fractionation of radionuclides. Furthermore, the distinct partitioning behavior of radionuclides in diatoms (previous studies) and coccolithophores (present study) explains the difference in the scavenging of radionuclides between diatom- and coccolithophore-dominated marine environments.

  2. World Health Organization cardiovascular risk stratification and target organ damage.

    PubMed

    Piskorz, D; Bongarzoni, L; Citta, L; Citta, N; Citta, P; Keller, L; Mata, L; Tommasi, A

    2016-01-01

    Prediction charts allow treatment to be targeted according to simple markers of cardiovascular risk; many algorithms do not recommend screening asymptomatic target organ damage which could change dramatically the assessment. To demonstrate that target organ damage is present in low cardiovascular risk hypertensive patients and it is more frequent and severe as global cardiovascular risk increases. Consecutive hypertensive patients treated at a single Latin American center. Cardiovascular risk stratified according to 2013 WHO/ISH risk prediction chart America B. Left ventricular mass assessed by Devereux method, left ventricular hypertrophy considered >95g/m(2) in women and >115g/m(2) in men. Transmitral diastolic peak early flow velocity to average septal/lateral peak early diastolic relaxation velocity (E/e' ratio) measured cut off value >13. Systolic function assessed by tissue Doppler average interventricular septum/lateral wall mitral annulus rate systolic excursion (s wave). A total of 292 patients were included of whom 159 patients (54.5%) had cardiovascular risk of <10%, 90 (30.8%) had cardiovascular risk of 10-20% and 43 (14.7%) had cardiovascular risk of >20%. Left ventricular hypertrophy was detected in 17.6% low risk patients, 27.8% in medium risk and 23.3% in high risk (p<0.05), abnormal E/e' ratio was found in 13.8%, 31.1% and 27.9%, respectively (p<0.05). Mean s wave was 8.03+8, 8.1+9 and 8.7+1cm/s for low, intermediate and high risk patients, respectively (p<0.025). Target organ damage is more frequent and severe in high risk; one over four subjects was misclassified due to the presence of asymptomatic target organ damage. Copyright © 2015 SEHLELHA. Published by Elsevier España, S.L.U. All rights reserved.

  3. A method for optimum PSA setting in the absence of a pure α or β emitter and its application in the determination of (237)Np/(233)Pa.

    PubMed

    Feng, Xiao-gui; He, Qian-ge; Wang, Jian-chen; Chen, Jing

    2014-11-01

    In the application of liquid scintillation counting (LSC), the α/β discrimination is carried out with the function of pulse shape analysis (PSA), which requires the setting of the optimum PSA level. The optimum PSA are usually determined by the generation of cross-over plots, whereby a pair of vials, one containing a pure α emitter and the other a pure β emitter, is counted. However, in some cases such as the determination of (237)Np/(233)Pa, a pure α emitter or a pure β emitter is not available. Therefore, we have developed a new approach to set the optimum PSA by measuring the sample itself of mixed α/β emitters. The count rate of the sample in the α-multi-channel analyzer changes monotonically with the increase of the PSA, and there is always an inflection point which is related to the optimum PSA. By fitting the data near the inflection point with the function y=ax(3)+bx(2)+cx+d, we can obtain the optimum PSA as -b/(3a), which can be used to determine the radioactivity of (237)Np/(233)Pa. The results obtained with this new approach were in good agreement with those obtained by HPGe γ spectrometry that was calibrated with an LSC sample of (237)Np/(233)Pa under a radioactive secular equilibrium. The new approach is promising to be used in simultaneous determination of gross α and β emitters, especially in the absence of a pure α or β emitter. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. Complete genomic sequences of Campylobacter jejuni strains RM3196 (233.94) and RM3197 (308.95) that were isolated from patients with Guillain-Barré Syndrome

    USDA-ARS?s Scientific Manuscript database

    An infection with Campylobacter jejuni subsp. jejuni (Cjj) is a leading cause of foodborne gastroenteritis in humans and also the most prevalent infection preceding Guillain-Barré syndrome (GBS). This study describes the complete genomic sequences of Cjj HS:41 strains RM3196 (233.94) and RM3197 (308...

  5. De novo 12q22.q23.3 duplication associated with temporal lobe epilepsy.

    PubMed

    Vari, Maria Stella; Traverso, Monica; Bellini, Tommaso; Madia, Francesca; Pinto, Francesca; Minetti, Carlo; Striano, Pasquale; Zara, Federico

    2017-08-01

    Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy and may be associated with acquired central nervous system lesions or could be genetic. Various susceptibility genes and environmental factors are believed to be involved in the aetiology of TLE, which is considered to be a heterogeneous, polygenic, and complex disorder. Rare point mutations in LGI1, DEPDC5, and RELN as well as some copy number variations (CNVs) have been reported in families with TLE patients. We perform a genetic analysis by Array-CGH in a patient with dysmorphic features and temporal lobe epilepsy. We report a de novo duplication of the long arm of chromosome 12. We confirm that 12q22-q23.3 is a candidate locus for familial temporal lobe epilepsy with febrile seizures and highlight the role of chromosomal rearrangements in patients with epilepsy and intellectual disability. Copyright © 2017 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

  6. Association of sequence variants on chromosomes 20, 11, and 5 (20q13.33, 11q23.3, and 5p15.33) with glioma susceptibility in a Chinese population.

    PubMed

    Chen, Hongyan; Chen, Yuanyuan; Zhao, Yao; Fan, Weiwei; Zhou, Keke; Liu, Yanhong; Zhou, Liangfu; Mao, Ying; Wei, Qingyi; Xu, Jianfeng; Lu, Daru

    2011-04-15

    Two genome-wide association studies of glioma in European populations identified 14 genetic variants strongly associated with risk of glioma, but it is unknown whether these variants are associated with glioma risk in Asian populations. The authors genotyped these 14 variants in 976 glioma patients and 1,057 control subjects to evaluate their associations with risk of glioma, particularly high-grade glioma (glioblastoma; n = 312), in a Chinese population (2004-2009). Overall, the authors identified 3 susceptibility loci for glioma risk at 20q13.33 (RTEL1 rs6010620 (P = 2.79 × 10(-6))), 11q23.3 (PHLDB1 rs498872 (P = 3.8 × 10(-6))), and 5p15.33 (TERT rs2736100 (P = 3.69 × 10(-4))) in this study population; these loci were also associated with glioblastoma risk (20q13.33: RTEL1 rs6010620 (P = 3.57 × 10(-7)); 11q23.3: PHLDB1 rs498872 (P = 7.24 × 10(-3)); 5p15.33: TERT rs2736100 and TERT rs2736098 (P = 1.21 × 10(-4) and P = 2.84 × 10(-4), respectively)). This study provides further evidence for 3 glioma susceptibility regions at 20q13.33, 11q23.3, and 5p15.33 in Chinese populations.

  7. Production of Thorium-229 at the ORNL High Flux Isotope Reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boll, Rose Ann; Garland, Marc A; Mirzadeh, Saed

    The investigation of targeted cancer therapy using -emitters has developed considerably in recent years and clinical trials have generated promising results. In particular, the initial clinical trials for treatment of acute myeloid leukemia have demonstrated the effectiveness of the -emitter 213Bi in killing cancer cells [1]. Pre-clinical studies have also shown the potential application of both 213Bi and its 225Ac parent radionuclide in a variety of cancer systems and targeted radiotherapy [2]. Bismuth-213 is obtained from a radionuclide generator system from decay of the 10-d 225Ac parent, a member of the 7340-y 229Th chain. Currently, 233U is the only viablemore » source for high purity 229Th; however, due to increasing difficulties associated with 233U safeguards, processing additional 233U is presently unfeasible. The recent decision to downblend and dispose of enriched 233U further diminished the prospects for extracting 229Th from 233U stock. Nevertheless, the anticipated growth in demand for 225Ac may soon exceed the levels of 229Th (~40 g or ~8 Ci; ~80 times the current ORNL 229Th stock) present in the aged 233U stockpile. The alternative routes for the production of 229Th, 225Ra and 225Ac include both reactor and accelerator approaches [3]. Here, we describe production of 229Th via neutron transmutation of 226Ra targets in the ORNL High Flux Isotope Reactor (HFIR).« less

  8. Brown spider phospholipase-D containing a conservative mutation (D233E) in the catalytic site: identification and functional characterization.

    PubMed

    Vuitika, Larissa; Gremski, Luiza Helena; Belisário-Ferrari, Matheus Regis; Chaves-Moreira, Daniele; Ferrer, Valéria Pereira; Senff-Ribeiro, Andrea; Chaim, Olga Meiri; Veiga, Silvio Sanches

    2013-11-01

    Brown spider (Loxosceles genus) bites have been reported worldwide. The venom contains a complex composition of several toxins, including phospholipases-D. Native or recombinant phospholipase-D toxins induce cutaneous and systemic loxoscelism, particularly necrotic lesions, inflammatory response, renal failure, and hematological disturbances. Herein, we describe the cloning, heterologous expression and purification of a novel phospholipase-D toxin, LiRecDT7 in reference to six other previously described in phospholipase-D toxin family. The complete cDNA sequence of this novel brown spider phospholipase-D isoform was obtained and the calculated molecular mass of the predicted mature protein is 34.4 kDa. Similarity analyses revealed that LiRecDT7 is homologous to the other dermonecrotic toxin family members particularly to LiRecDT6, sharing 71% sequence identity. LiRecDT7 possesses the conserved amino acid residues involved in catalysis except for a conservative mutation (D233E) in the catalytic site. Purified LiRecDT7 was detected as a soluble 36 kDa protein using anti-whole venom and anti-LiRecDT1 sera, indicating immunological cross-reactivity and evidencing sequence-epitopes identities similar to those of other phospholipase-D family members. Also, LiRecDT7 exhibits sphingomyelinase activity in a concentration dependent-manner and induces experimental skin lesions with swelling, erythema and dermonecrosis. In addition, LiRecDT7 induced a massive inflammatory response in rabbit skin dermis, which is a hallmark of brown spider venom phospholipase-D toxins. Moreover, LiRecDT7 induced in vitro hemolysis in human erythrocytes and increased blood vessel permeability. These features suggest that this novel member of the brown spider venom phospholipase-D family, which naturally contains a mutation (D233E) in the catalytic site, could be useful for future structural and functional studies concerning loxoscelism and lipid biochemistry. 1- Novel brown spider

  9. Linking smokers to a quitline: randomized controlled effectiveness trial of a support person intervention that targets non-smokers

    PubMed Central

    Patten, Christi A.; Boyle, Raymond; Tinkelman, David; Brockman, Tabetha A.; Lukowski, Amy; Decker, Paul A.; D’Silva, Joanne; Lichtenstein, Edward; Zhu, Shu-Hong

    2017-01-01

    Abstract Evidence-based treatments (e.g. quitlines) are greatly underutilized by smokers limiting their public health impact. A three-session phone intervention for nonsmoking family members and friends (i.e. support persons) was successful for increasing smoker quitline enrollment. To enhance the intervention’s potential translatability, in this study, we delivered treatment for the non-smoker within ongoing quitline services and compared the efficacy of the three-call intervention to a streamlined version (one call). A total of 704 adult non-smokers (85% female, 95% White) wanting to help a smoker quit and recruited statewide in Minnesota participated in this randomized controlled trial with parallel groups. Non-smokers received mailed written materials and were randomly assigned to a control condition (no additional treatment, n = 235), or to a one- (n = 233) or three-call (n = 236) intervention delivered by quitline coaches. The main outcome was smoker quitline enrollment through 7-month follow-up. Smoker quitline enrollment was similar for those linked to non-smokers in the one- and three-call interventions (14.6% [34/233] and 14.8% [35/236]), and higher than for smokers linked to control participants (6.4% [15/235]), P = 0.006. Just one quitline coaching call delivered to non-smokers increased treatment enrollment among smokers. The reach of quitlines could be enhanced by targeting the social support network of smokers. PMID:28854569

  10. Fertile-to-fissile and fission measurements for depleted uranium and thorium bombarded by 800-MeV protons

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gilmore, J.S.; Russell, G.J.; Robinson, H.

    Axial distributions of fissions and of fertile-to-fissile conversions in thick depleted uranium and thorium targets bombarded by 800-MeV protons have been measured. The amounts of /sup 239/Pu and /sup 233/U produced were determined by measuring the yields of /sup 239/Np and /sup 233/Pa, respectively. The number of fissions was deduced from fission product mass-yield curves. Integration of the axial distributions gave the total number of conversions and fissions occurring in the targets. For the uranium target, experimental results were 5.90 +- 0.25 fissions and 3.81 +- 0.01 atoms of /sup 239/Pu produced per incident portion. Corresponding calculated results were 6.14more » +- 0.04 and 3.88 +- 0.03. In the thorium target, 1.56 +- 0.25 fissions and 1.25 +- 0.01 atoms of /sup 233/U per incident proton were measured; the calculated values were 1.54 +- 0.01 fissions and 1.27 +- 0.01 atom/proton.« less

  11. Quantitative trait loci at the 11q23.3 chromosomal region related to dyslipidemia in the population of Andhra Pradesh, India.

    PubMed

    Pranavchand, Rayabarapu; Reddy, Battini Mohan

    2017-06-13

    Given the characteristic atherogenic dyslipidemia of south Indian population and crucial role of APOA1, APOC3, APOA4 and APOA5 genes clustered in 11q23.3 chromosomal region in regulating lipoprotein metabolism and cholesterol homeostasis, a large number of recently identified variants are to be explored for their role in regulating the serum lipid parameters among south Indians. Using fluidigm SNP genotyping platform, a prioritized set of 96 SNPs of the 11q23.3 chromosomal region were genotyped on 516 individuals from Hyderabad, India, and its vicinity and aged >45 years. The linear regression analysis of the individual lipid traits viz., TC, LDLC, HDLC, VLDL and TG with each of the 78 SNPs that confirm to HWE and with minor allele frequency > 1%, suggests 23 of those to be significantly associated (p ≤ 0.05) with at least one of these quantitative traits. Most importantly, the variant rs632153 is involved in elevating TC, LDLC, TG and VLDLs and probably playing a crucial role in the manifestation of dyslipidemia. Additionally, another three SNPs rs633389, rs2187126 and rs1263163 are found risk conferring to dyslipidemia by elevating LDLC and TC levels in the present population. Further, the ROC (receiver operating curve) analysis for the risk scores and dyslipidemia status yielded a significant area under curve (AUC) = 0.675, suggesting high discriminative power of the risk variants towards the condition. The interaction analysis suggests rs10488699-rs2187126 pair of the BUD13 gene to confer significant risk (Interaction odds ratio = 14.38, P = 7.17 × 10 5 ) towards dyslipidemia by elevating the TC levels (β = 37.13, p = 6.614 × 10 5 ). On the other hand, the interaction between variants of APOA1 gene and BUD13 and/or ZPR1 regulatory genes at this region are associated with elevated TG and VLDL. The variants at 11q23.3 chromosomal region seem to determine the quantitative lipid traits and in turn dyslipidemia in the population of Hyderabad

  12. Two Novel Tyrosinase Inhibitory Sesquiterpenes Induced by CuCl2 from a Marine-Derived Fungus Pestalotiopsis sp. Z233

    PubMed Central

    Wu, Bin; Wu, Xiaodan; Sun, Min; Li, Minhui

    2013-01-01

    Two new sesquiterpenes, 1β,5α,6α,14-tetraacetoxy-9α-benzoyloxy-7βH-eudesman-2β,11-diol (1) and 4α,5α-diacetoxy-9α-benzoyloxy-7βH-eudesman-1β,2β,11,14-tetraol (2), were produced as stress metabolites in the cultured mycelia of Pestalotiopsis sp. Z233 isolated from the algae Sargassum horneri in response to abiotic stress elicitation by CuCl2. Their structures were established by spectroscopic means. New compounds 1 and 2 showed tyrosinase inhibitory activities with IC50 value of 14.8 µM and 22.3 µM. PMID:23917067

  13. Two novel tyrosinase inhibitory sesquiterpenes induced by CuCl2 from a marine-derived fungus Pestalotiopsis sp. Z233.

    PubMed

    Wu, Bin; Wu, Xiaodan; Sun, Min; Li, Minhui

    2013-08-02

    Two new sesquiterpenes, 1β,5α,6α,14-tetraacetoxy-9α-benzoyloxy-7β H-eudesman-2β,11-diol (1) and 4α,5α-diacetoxy-9α-benzoyloxy-7βH-eudesman-1β,2β,11, 14-tetraol (2), were produced as stress metabolites in the cultured mycelia of Pestalotiopsis sp. Z233 isolated from the algae Sargassum horneri in response to abiotic stress elicitation by CuCl2. Their structures were established by spectroscopic means. New compounds 1 and 2 showed tyrosinase inhibitory activities with IC50 value of 14.8 µM and 22.3 µM.

  14. Application of the SCALE TSUNAMI Tools for the Validation of Criticality Safety Calculations Involving 233U

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mueller, Don; Rearden, Bradley T; Hollenbach, Daniel F

    2009-02-01

    The Radiochemical Development Facility at Oak Ridge National Laboratory has been storing solid materials containing 233U for decades. Preparations are under way to process these materials into a form that is inherently safe from a nuclear criticality safety perspective. This will be accomplished by down-blending the {sup 233}U materials with depleted or natural uranium. At the request of the U.S. Department of Energy, a study has been performed using the SCALE sensitivity and uncertainty analysis tools to demonstrate how these tools could be used to validate nuclear criticality safety calculations of selected process and storage configurations. ISOTEK nuclear criticality safetymore » staff provided four models that are representative of the criticality safety calculations for which validation will be needed. The SCALE TSUNAMI-1D and TSUNAMI-3D sequences were used to generate energy-dependent k{sub eff} sensitivity profiles for each nuclide and reaction present in the four safety analysis models, also referred to as the applications, and in a large set of critical experiments. The SCALE TSUNAMI-IP module was used together with the sensitivity profiles and the cross-section uncertainty data contained in the SCALE covariance data files to propagate the cross-section uncertainties ({Delta}{sigma}/{sigma}) to k{sub eff} uncertainties ({Delta}k/k) for each application model. The SCALE TSUNAMI-IP module was also used to evaluate the similarity of each of the 672 critical experiments with each application. Results of the uncertainty analysis and similarity assessment are presented in this report. A total of 142 experiments were judged to be similar to application 1, and 68 experiments were judged to be similar to application 2. None of the 672 experiments were judged to be adequately similar to applications 3 and 4. Discussion of the uncertainty analysis and similarity assessment is provided for each of the four applications. Example upper subcritical limits (USLs) were

  15. Utilization of non-weapons-grade plutonium and highly enriched uranium with breeding of the 233U isotope in the VVER reactors using thorium and heavy water

    NASA Astrophysics Data System (ADS)

    Marshalkin, V. E.; Povyshev, V. M.

    2015-12-01

    A method for joint utilization of non-weapons-grade plutonium and highly enriched uranium in the thorium-uranium—plutonium oxide fuel of a water-moderated reactor with a varying water composition (D2O, H2O) is proposed. The method is characterized by efficient breeding of the 233U isotope and safe reactor operation and is comparatively simple to implement.

  16. On the Relative Signs of "ROT-Effects" in Ternary and Binary Fission of 233U and 235U Nuclei Induced by Polarized Cold Neutrons

    NASA Astrophysics Data System (ADS)

    Danilyan, G. V.

    2018-02-01

    Signs of the ROT-effects in ternary fission of 233U and 235U experimentally defined by PNPI group are the same, whereas in binary fission defined by ITEP group are opposite. This contradiction cannot be explained by the errors in the experiments of both groups, since such instrumental effects would be too large not to be noticed. Therefore, it is necessary to find the answer to this problem in the differences of the ternary and binary fission mechanisms.

  17. Utilization of non-weapons-grade plutonium and highly enriched uranium with breeding of the {sup 233}U isotope in the VVER reactors using thorium and heavy water

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marshalkin, V. E., E-mail: marshalkin@vniief.ru; Povyshev, V. M.

    A method for joint utilization of non-weapons-grade plutonium and highly enriched uranium in the thorium–uranium—plutonium oxide fuel of a water-moderated reactor with a varying water composition (D{sub 2}O, H{sub 2}O) is proposed. The method is characterized by efficient breeding of the {sup 233}U isotope and safe reactor operation and is comparatively simple to implement.

  18. Defense Technical Information Center Thesaurus

    DTIC Science & Technology

    2000-10-01

    acquisition radar 4 + Indicates existence of further generic levels of the term DTIC Thesaurus Actuators Acridines Actinide series (cont.) Activated sintering...BT Heterocyclic compounds+ Uranium+ BT Sintering Acrilan Actinide series compounds Activated sludge process use Acrylonitrile polymers RT Actinide...Waste treatment+ Protactinium compounds Acronyms Thorium compounds+ Activation use Abbreviations Transuranium compounds+ UF Energizing Uranium compounds

  19. Comment on “Modeling of opposition effects with ensembles of clusters: Interplay of various scattering mechanisms” by Elena V. Petrova, Victor P. Tishkovets, Klaus Jockers, 2007 [Icarus 188, 233 245

    NASA Astrophysics Data System (ADS)

    Shkuratov, Yuriy G.; Zubko, Evgenij S.

    2008-04-01

    We show that the mechanism called "near-field effect" [e.g., Petrova, E.V., Tishkovets, V.P., Jockers, K., 2007. Icarus 188, 233-245], which is used to explain wide-phase-angle negative polarization branch observed for planetary regoliths and cometary comas, is not realistic as it contradicts laboratory experiments and results of modeling with discrete dipole approximation calculations.

  20. Dissemination of VIM-2 producing Pseudomonas aeruginosa ST233 at tertiary care hospitals in Egypt.

    PubMed

    Zafer, Mai Mahmoud; Al-Agamy, Mohamed Hamed; El-Mahallawy, Hadir Ahmed; Amin, Magdy Aly; El Din Ashour, Seif

    2015-03-12

    Pseudomonas aeruginosa is an important nosocomial pathogen, commonly causing infections in immunocompromised patients. The aim of this study was to examine the genetic relatedness of metallo-beta-lactamase (MBL) producing carbapenem resistant Pseudomonas aeruginosa clinical isolates collected from 2 tertiary hospitals in Cairo, Egypt using Multi Locus sequence typing (MLST). Phenotypic and genotypic detection of metallo-beta-lactamase for forty eight non-duplicate carbapenem resistant P. aeruginosa isolates were carried out. DNA sequencing and MLST were done. The bla VIM-2 gene was highly prevalent (28/33 strains, 85%) among 33 MBL-positive P.aeruginosa isolates. MLST revealed eleven distinct Sequence Types (STs). A unique ST233 clone producing VIM-2 was documented by MLST in P.aeruginosa strains isolated from Cairo university hospitals. The high prevalence of VIM-2 producers was not due to the spread of a single clone. The findings of the present study clearly demonstrate that clones of VIM-2 positive in our hospitals are different from those reported from European studies. Prevalence of VIM-2 producers of the same clone was detected from surgical specimens whereas oncology related specimens were showing diverse clones.

  1. Amniotic membrane transplantation for ocular disease: a review of the first 233 cases from the UK user group

    PubMed Central

    Saw, Valerie P J; Minassian, Darwin; Dart, John K G; Ramsay, Andrew; Henderson, Hugo; Poniatowski, Stefan; Warwick, Ruth M; Cabral, Suzanne

    2007-01-01

    Background Amniotic membrane transplantation (AMT), as a new tool in the armamentarium of therapies available for ocular surface problems, became widely available in the UK in 1998. This study evaluates the indications for treatment, the surgical procedures used, and the results of a subset of the first AMT cases carried out by the group using this nationally available supply. This user group model provides data which is different from that obtained from uncontrolled case series, or clinical trials, and may be more representative of the outcomes that can be expected when a procedure becomes widely available. Methods The first 233 AMTs, performed by the UK user group, were evaluated by audit and outcomes were assessed at 3 months. Results Of the 233 transplants, there were 126 (54.1%) valid outcome returns: the outcome for persistent epithelial defects was a healed and stable surface in 11/35 (31.4%, 95% CI 16.9 to 49.3); for chemical/thermal injuries, a healed uninflamed eye with clear cornea in 5/18 (27.8%, 95% CI 9.7 to 53.4); for bullous keratopathy a pain‐free, stable surface without bullae in 4/18 (22.2%, 95% CI 6.4 to 47.6); for ocular surface reconstruction, an epithelialised uninflamed conjunctiva without scarring in 12/23 (52.2%, 95% CI 30.6 to 73.2); and for limbal stem cell deficiency, a corneal phenotype in 4/7 (57.1%). The operative technique least associated with failure was use of a bandage contact lens at the end of the procedure (OR 0.19, 95% CI 0.06 to 0.59, p = 0.004). Previous treatment with topical steroids was significantly associated with failure (OR 5.70, 95% CI 1.77 to 18.43, p = 0.004). Conclusion Although the outcome criteria used in this study were stringent, and the follow‐up duration was short, the results of AMT by this user group were generally less favourable than those of previously reported case series. Controlled clinical trials would improve the quality of evidence for use of amniotic membrane in ocular disease

  2. REGENERATION OF FISSION-PRODUCT-CONTAINING MAGNESIUM-THORIUM ALLOYS

    DOEpatents

    Chiotti, P.

    1964-02-01

    A process of regenerating a magnesium-thorium alloy contaminated with fission products, protactinium, and uranium is presented. A molten mixture of KCl--LiCl-MgCl/sub 2/ is added to the molten alloy whereby the alkali, alkaline parth, and rare earth fission products (including yttrium) and some of the thorium and uranium are chlorinated and

  3. Total Kinetic Energy and Fragment Mass Distribution of Neutron-Induced Fission of U-233

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Higgins, Daniel James; Schmitt, Kyle Thomas; Mosby, Shea Morgan

    Properties of fission in U-233 were studied at the Los Alamos Neutron Science Center (LANSCE) at incident neutron energies from thermal to 40 MeV at both the Lujan Neutron Scattering Center flight path 12 and at WNR flight path 90-Left from Dec 2016 to Jan 2017. Fission fragments are observed in coincidence using a twin ionization chamber with Frisch grids. The average total kinetic energy (TKE) released from fission and fragment mass distributions are calculated from observations of energy deposited in the detector and conservation of mass and momentum. Accurate experimental measurements of these parameters are necessary to better understandmore » the fission process and obtain data necessary for calculating criticality. The average TKE released from fission has been well characterized for several isotopes at thermal neutron energy, however, few measurements have been made at fast neutron energies. This experiment expands on previous successful experiments using an ionization chamber to measure TKE and fragment mass distributions of U-235, U-238, and Pu-239. This experiment requires the full spectrum of neutron energies and can therefore only be performed at a small number of facilities in the world. The required full neutron energy spectrum is obtained by combining measurements from WNR 90L and Lujan FP12 at LANSCE.« less

  4. [Preparation of ASODN-protamine-HSA-PLGA nanoparticles and initial evaluation of their nucleus targeting property in vitro].

    PubMed

    Zhang, Yi; Yuan, Li; Yan, Xiao-ling; Gong, Tao; Liu, Jie; Zhang, Zhi-rong; Sun, Xun

    2009-05-01

    To develop a novel non-viral gene delivery system-SODN-Protamine-HSA-PLGA (ASODN-P/H-PLGA-NP) and investigate its nucleus targeting potential in vitro. ASODN-P/H-PLGA-NP was prepared by mixing the protamine sulfate and HSA. Then the PLGA nanoparticles were prepared using double-emulsion evaporation technique, followed by addition of ASODN to the prepared P/H complex. The morphology of ASODN-P/H-PLGA-NP was observed by transmission electron microscopy. The diameter, PDI, and surface charge of ASODN-P/H-PLGA-NP were measured by photo correlation spectroscopy (PCS). The encapsulation efficiency of ASODN was determined by double step method. The cytotoxicity of ASODN-P/H-PLGA-NP was investigated by MTT assays. The ability to enter the squamouse carcinoma: Hep-2 cell line and its nucleus targeting property were observed by confocal laser scanning microscope. The average diameter, PDI, zeta potential, and encapsulation efficiency of ASODN-P/H-PLGA-NP were 128 nm, 0.234, -23.3 mV, and 78.45%, respectively. ASODN-P/H-PLGA-NP could protect the ASODN from the shear force in the ultrasound process during preparation. ASODN-P/H-PLGA-NP couldenter Hep-2 cells and have certain level of nucleus targeting property. ASODN-P/H-PLGA-NP can be prepared easily with small particle sizes and low cytotoxicity, which might be employed as a good non-viral vector for applications in ASODN delivery to nucleus.

  5. A high-affinity [ 18F]-labeled phosphoramidate peptidomimetic PSMA-targeted inhibitor for PET imaging of prostate cancer

    DOE PAGES

    Ganguly, Tanushree; Dannoon, Shorouk; Hopkins, Mark R.; ...

    2015-06-09

    Here in this study, a structurally modified phosphoramidate scaffold, with improved prostate-specific membrane antigen (PSMA) avidity, stability and in vivo characteristics, as a PET imaging agent for prostate cancer (PCa), was prepared and evaluated. p-Fluorobenzoyl-aminohexanoate and 2-(3-hydroxypropyl)glycine were introduced into the PSMA-targeting scaffold yielding phosphoramidate 5. X-ray crystallography was performed on the PSMA/5 complex. [ 18F]5 was synthesized, and cell uptake and internalization studies were conducted in PSMA(+) LNCaP and CWR22Rv1 cells and PSMA(-) PC-3 cells. In vivo PET imaging and biodistribution studies were performed at 1 and 4 h post injection in mice bearing CWR22Rv1 tumor, with or withoutmore » blocking agent. The crystallographic data showed interaction of the p-fluorobenzoyl group with an arene-binding cleft on the PSMA surface. In vitro studies revealed elevated uptake of [ 18F]5 in PSMA(+) cells (2.2% in CWR22Rv1 and 12.1% in LNCaP) compared to PSMA(-) cells (0.08%) at 4 h. In vivo tumor uptake of 2.33% ID/g and tumor-to-blood ratio of 265:1 was observed at 4 h. In conclusion, we have successfully synthesized, radiolabeled and evaluated a new PSMA-targeted PET agent. The crystal structure of the PSMA/5 complex highlighted the interactions within the arene-binding cleft contributing to the overall complex stability. The high target uptake and rapid non-target clearance exhibited by [ 18F]5 in PSMA(+) xenografts substantiates its potential use for PET imaging of PCa.« less

  6. Rebuttal to comment on “Modeling of opposition effects with ensembles of clusters: Interplay of various scattering mechanisms” by Elena V. Petrova, Victor P. Tishkovets, Klaus Jockers, 2007 [Icarus 188, 233 245

    NASA Astrophysics Data System (ADS)

    Petrova, Elena V.; Tishkovets, Victor P.; Jockers, Klaus

    2008-04-01

    Shkuratov and Zubko [Shkuratov, Yu.G., Zubko, E., 2008. Icarus 194, 850-852] criticize our paper [Petrova, E.V., Tishkovets, V.P., Jockers, K., 2007. Icarus 188, 233-245]. With this comment we reply to this criticism. We show that the experimental data and the modeling calculations presented by these authors cannot disprove the near-field effect as an important contributor to the scattering mechanisms considered in our paper.

  7. OCO-2 Observation and Validation Overview: Observations Data Modes and Target Observations, Taken During the First 15 Months of Operations

    NASA Astrophysics Data System (ADS)

    Osterman, G. B.; Fisher, B.; Wunch, D.; Eldering, A.; Wennberg, P. O.; Roehl, C. M.; Naylor, B. J.; Lee, R.; Pollock, R.; Gunson, M. R.

    2015-12-01

    The OCO-2 instrument was successfully launched on July 2, 2014 from Vandenberg Air Force Base in California. The instrument reached its observational orbit about three weeks later. The spacecraft is at the head of the A-train satellites and began collecting operational data on Sept 5, 2014. OCO-2 makes measurements in three modes: nadir, glint and target. Target observations are designed to provide large amounts of data in a small area near a ground validation site. The instruments of the Total Carbon Column Observing Network (TCCON) provide the ground validation data for the OCO-2 XCO2 observations and comparisons to TCCON form the basis of the OCO-2 validation plan. There are now 27 locations at which OCO-2 can perform target observations and CCON sites make up 23 of those possible target locations. For its first year in orbit, OCO-2 operated in nadir mode for 16 days and then in glint mode for 16 days. Each 16-day cycle spans 233 orbits. On July 1, 2015, OCO-2 changed to an observational mode of alternating nadir and glint measurements on an orbit-by-orbit basis. By December 2015, this operational mode may be modified such that orbits that measure only over ocean will always observed in glint mode. In this presentation we will provide information on the observations made by OCO-2 during its first 15 month in operations. We will show maps of the OCO-2 ground tracks and XCO2 data, calendars illustrating the observational schedule and statistics on the target observations taken. We will provide more information on what is involved in making target observations and how it affects the standard operational data acquisition patterns. Changes to the standard observational patterns of OCO-2 and to the list of locations for target observations will be discussed as well. We will provide an overview of some of the validation related analysis being done using nadir and glint mode OCO-2 data in addition to an overview on validation analyses that do not directly utilize TCCON

  8. Development and validation of an ICP-MS method for the determination of elemental impurities in TP-6076 active pharmaceutical ingredient (API) according to USP 〈232〉/〈233〉.

    PubMed

    Chahrour, Osama; Malone, John; Collins, Mark; Salmon, Vrushali; Greenan, Catherine; Bombardier, Amy; Ma, Zhongze; Dunwoody, Nick

    2017-10-25

    The new guidelines of the United States pharmacopeia (USP), European pharmacopeia (EP) and international conference on harmonization (ICH) regulating elemental impurities limits in pharmaceuticals signify the end of unspecific analysis of metals as outlined in USP 〈231〉. The new guidelines specify both daily doses and concentration/limits of elemental impurities in pharmaceutical final products, active pharmaceutical ingredients (API) and excipients. In chapter USP 〈233〉 method implementation, validation and quality control during the analytical process are described. We herein report the use of a stabilising matrix that overcomes low spike recovery problem encountered with Os and allows the determination of all USP required elemental impurities (As, Cd, Hg, Pb, V, Cr, Ni, Mo, Cu, Pt, Pd, Ru, Rh, Os and Ir) in a single analysis. The matrix was used in the validation of a method to determine elemental impurities in TP-6076 active pharmaceutical ingredient (API) by ICP-MS according to the procedures defined in USP〈233〉 and to GMP requirements. This validation will support the regulatory submission of TP-6076 which is a novel tetracycline analogue effective against the most urgent multidrug-resistant gram-negative bacteria. Evaluation of TP-6076 in IND-enabling toxicology studies has led to the initiation of a phase 1 clinical trial. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Nylon and teflon scribe effect on NBR to Chemlok 233 and NBR to NBR bond interfaces

    NASA Technical Reports Server (NTRS)

    Jensen, S. K.

    1990-01-01

    A study was requested by Manufacturing Engineering to determine what effects marking with nylon (6/6) and Teflon scribes may have on subsequent bonding. Witness panel bond specimens were fabricated by the development lab to test both acrylonitrile butadiene rubber (NBR) to Chemlok and NBR to NBR after controlled exposure. The nylon rod used as a scribe tool demonstrates virtually no bond deterioration when used to scribe lines on either the Chemlok to NBR surfaces or the NBR to NBR interface. Lab test results indicate that the nylon rod-exposed samples produce tensile and peel values very similar to the control samples and the Teflon exposed samples produce tensile and peel values much lower than the control samples. Visual observation of the failure surfaces of the tested samples shows that Teflon scribing produces an obvious contamination to the surface and the nylon produces no effect. Photographs of test samples are provided. It is concluded that Teflon stock used as a scribe tool on a Chemlok 233 to NBR surface or an NBR to NBR surface has a detrimental effect on the bond integrity on either of these bond interfaces. Therefore, it is recommended that the nylon rod continue to be used where a scribe line is required in the redesigned solid rocket motor segment insulation layup operations. The use of Teflon scribes should not be considered.

  10. Identification and characterization of miRNAs and targets in flax (Linum usitatissimum) under saline, alkaline, and saline-alkaline stresses.

    PubMed

    Yu, Ying; Wu, Guangwen; Yuan, Hongmei; Cheng, Lili; Zhao, Dongsheng; Huang, Wengong; Zhang, Shuquan; Zhang, Liguo; Chen, Hongyu; Zhang, Jian; Guan, Fengzhi

    2016-05-27

    MicroRNAs (miRNAs) play a critical role in responses to biotic and abiotic stress and have been characterized in a large number of plant species. Although flax (Linum usitatissimum L.) is one of the most important fiber and oil crops worldwide, no reports have been published describing flax miRNAs (Lus-miRNAs) induced in response to saline, alkaline, and saline-alkaline stresses. In this work, combined small RNA and degradome deep sequencing was used to analyze flax libraries constructed after alkaline-salt stress (AS2), neutral salt stress (NSS), alkaline stress (AS), and the non-stressed control (CK). From the CK, AS, AS2, and NSS libraries, a total of 118, 119, 122, and 120 known Lus-miRNAs and 233, 213, 211, and 212 novel Lus-miRNAs were isolated, respectively. After assessment of differential expression profiles, 17 known Lus-miRNAs and 36 novel Lus-miRNAs were selected and used to predict putative target genes. Gene ontology term enrichment analysis revealed target genes that were involved in responses to stimuli, including signaling and catalytic activity. Eight Lus-miRNAs were selected for analysis using qRT-PCR to confirm the accuracy and reliability of the miRNA-seq results. The qRT-PCR results showed that changes in stress-induced expression profiles of these miRNAs mirrored expression trends observed using miRNA-seq. Degradome sequencing and transcriptome profiling showed that expression of 29 miRNA-target pairs displayed inverse expression patterns under saline, alkaline, and saline-alkaline stresses. From the target prediction analysis, the miR398a-targeted gene codes for a copper/zinc superoxide dismutase, and the miR530 has been shown to explicitly target WRKY family transcription factors, which suggesting that these two micRNAs and their targets may significant involve in the saline, alkaline, and saline-alkaline stress response in flax. Identification and characterization of flax miRNAs, their target genes, functional annotations, and gene

  11. Short communication an interferon-γ ELISPOT assay with two cytotoxic T cell epitopes derived from HTLV-1 tax region 161-233 discriminates HTLV-1-associated myelopathy/tropical spastic paraparesis patients from asymptomatic HTLV-1 carriers in a Peruvian population.

    PubMed

    Best, Ivan; López, Giovanni; Talledo, Michael; MacNamara, Aidan; Verdonck, Kristien; González, Elsa; Tipismana, Martín; Asquith, Becca; Gotuzzo, Eduardo; Vanham, Guido; Clark, Daniel

    2011-11-01

    HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic and progressive disorder caused by the human T-lymphotropic virus type 1 (HTLV-1). In HTLV-1 infection, a strong cytotoxic T cell (CTL) response is mounted against the immunodominant protein Tax. Previous studies carried out by our group reported that increased IFN-γ enzyme-linked immunospot (ELISPOT) responses against the region spanning amino acids 161 to 233 of the Tax protein were associated with HAM/TSP and increased HTLV-1 proviral load (PVL). An exploratory study was conducted on 16 subjects with HAM/TSP, 13 asymptomatic carriers (AC), and 10 HTLV-1-seronegative controls (SC) to map the HAM/TSP-associated CTL epitopes within Tax region 161-233. The PVL of the infected subjects was determined and the specific CTL response was evaluated with a 6-h incubation IFN-γ ELISPOT assay using peripheral blood mononuclear cells (PBMCs) stimulated with 16 individual overlapping peptides covering the Tax region 161-233. Other proinflammatory and Th1/Th2 cytokines were also quantified in the supernatants by a flow cytometry multiplex assay. In addition, a set of human leukocyte antigen (HLA) class I alleles that bind with high affinity to the CTL epitopes of interest was determined using computational tools. Univariate analyses identified an association between ELISPOT responses to two new CTL epitopes, Tax 173-185 and Tax 181-193, and the presence of HAM/TSP as well as an increased PVL. The HLA-A*6801 allele, which is predicted to bind to the Tax 181-193 peptide, was overpresented in the HAM/TSP patients tested.

  12. Absolute rate constants for the reaction of OH with cyclopentane and cycloheptane from 233 to 351 K.

    PubMed

    Gennaco, Michael A; Huang, Yi-wen; Hannun, Reem A; Dransfield, Timothy J

    2012-12-27

    Absolute rate constant measurements for the reactions of OH with cyclopentane and cycloheptane in the gas phase in 6-8 Torr of nitrogen from 233 to 351 K in the Harvard University High-Pressure Flow System (HPFS) are reported. Hydroxyl concentrations were measured using laser-induced fluorescence, and alkane concentrations were measured using Fourier transform infrared spectroscopy. Results were fit to a modified Arrhenius equation based on transition state theory (ignoring tunneling): k(T) = B e(-E(a)/T)/T(1 - e(-1.44ν(1)/T))(2)(1 - e(-1.44ν(2)/T)), with ν(1) and ν(2) bending frequencies set to 280 and 500 cm(-1) . Results were as follows for E(a) (K) and k (298) (10(-12) cm(3) s(-1)): cyclopentane, 460 ± 32, 4.85; cycloheptane, 319 ± 36, 9.84. This work represents the second absolute temperature-dependent rate constant measurement reported for cycloheptane, and the third absolute temperature-dependent rate constant measurement reported near room temperature for the reaction of OH and cyclopentane. For the title reactions, the reaction barriers reported here are in agreement with the reaction barrier previously reported for cyclohexane and considerably higher than the barrier previously reported for cyclo-octane, a result that is not predicted by our current understanding of hydrocarbon reactivity.

  13. Young planets under extreme UV irradiation. I. Upper atmosphere modelling of the young exoplanet K2-33b

    NASA Astrophysics Data System (ADS)

    Kubyshkina, D.; Lendl, M.; Fossati, L.; Cubillos, P. E.; Lammer, H.; Erkaev, N. V.; Johnstone, C. P.

    2018-04-01

    The K2-33 planetary system hosts one transiting 5 R⊕ planet orbiting the young M-type host star. The planet's mass is still unknown, with an estimated upper limit of 5.4 MJ. The extreme youth of the system (<20 Myr) gives the unprecedented opportunity to study the earliest phases of planetary evolution, at a stage when the planet is exposed to an extremely high level of high-energy radiation emitted by the host star. We perform a series of 1D hydrodynamic simulations of the planet's upper atmosphere considering a range of possible planetary masses, from 2 to 40 M⊕, and equilibrium temperatures, from 850 to 1300 K, to account for internal heating as a result of contraction. We obtain temperature profiles mostly controlled by the planet's mass, while the equilibrium temperature has a secondary effect. For planetary masses below 7-10 M⊕, the atmosphere is subject to extremely high escape rates, driven by the planet's weak gravity and high thermal energy, which increase with decreasing mass and/or increasing temperature. For higher masses, the escape is instead driven by the absorption of the high-energy stellar radiation. A rough comparison of the timescales for complete atmospheric escape and age of the system indicates that the planet is more massive than 10 M⊕.

  14. [Target volume margins for lung cancer: internal target volume/clinical target volume].

    PubMed

    Jouin, A; Pourel, N

    2013-10-01

    The aim of this study was to carry out a review of margins that should be used for the delineation of target volumes in lung cancer, with a focus on margins from gross tumour volume (GTV) to clinical target volume (CTV) and internal target volume (ITV) delineation. Our review was based on a PubMed literature search with, as a cornerstone, the 2010 European Organisation for Research and Treatment of Cancer (EORTC) recommandations by De Ruysscher et al. The keywords used for the search were: radiotherapy, lung cancer, clinical target volume, internal target volume. The relevant information was categorized under the following headings: gross tumour volume definition (GTV), CTV-GTV margin (first tumoural CTV then nodal CTV definition), in field versus elective nodal irradiation, metabolic imaging role through the input of the PET scanner for tumour target volume and limitations of PET-CT imaging for nodal target volume definition, postoperative radiotherapy target volume definition, delineation of target volumes after induction chemotherapy; then the internal target volume is specified as well as tumoural mobility for lung cancer and respiratory gating techniques. Finally, a chapter is dedicated to planning target volume definition and another to small cell lung cancer. For each heading, the most relevant and recent clinical trials and publications are mentioned. Copyright © 2013. Published by Elsevier SAS.

  15. Separation of Californium from other Actinides

    DOEpatents

    Mailen, J C; Ferris, L M

    1973-09-25

    A method is provided for separating californium from a fused fluoride composition containing californium and at least one element selected from the group consisting of plutonium, americium, curium, uranium, thorium, and protactinium which comprises contacting said fluoride composition with a liquid bismuth phase containing sufficient lithium or thorium to effect transfer of said actinides to the bismuth phase and then contacting the liquid bismuth phase with molten LiCl to effect selective transfer of californium to the chloride phase.

  16. A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.

    PubMed

    Tomlinson, Ian P M; Webb, Emily; Carvajal-Carmona, Luis; Broderick, Peter; Howarth, Kimberley; Pittman, Alan M; Spain, Sarah; Lubbe, Steven; Walther, Axel; Sullivan, Kate; Jaeger, Emma; Fielding, Sarah; Rowan, Andrew; Vijayakrishnan, Jayaram; Domingo, Enric; Chandler, Ian; Kemp, Zoe; Qureshi, Mobshra; Farrington, Susan M; Tenesa, Albert; Prendergast, James G D; Barnetson, Rebecca A; Penegar, Steven; Barclay, Ella; Wood, Wendy; Martin, Lynn; Gorman, Maggie; Thomas, Huw; Peto, Julian; Bishop, D Timothy; Gray, Richard; Maher, Eamonn R; Lucassen, Anneke; Kerr, David; Evans, D Gareth R; Schafmayer, Clemens; Buch, Stephan; Völzke, Henry; Hampe, Jochen; Schreiber, Stefan; John, Ulrich; Koessler, Thibaud; Pharoah, Paul; van Wezel, Tom; Morreau, Hans; Wijnen, Juul T; Hopper, John L; Southey, Melissa C; Giles, Graham G; Severi, Gianluca; Castellví-Bel, Sergi; Ruiz-Ponte, Clara; Carracedo, Angel; Castells, Antoni; Försti, Asta; Hemminki, Kari; Vodicka, Pavel; Naccarati, Alessio; Lipton, Lara; Ho, Judy W C; Cheng, K K; Sham, Pak C; Luk, J; Agúndez, Jose A G; Ladero, Jose M; de la Hoya, Miguel; Caldés, Trinidad; Niittymäki, Iina; Tuupanen, Sari; Karhu, Auli; Aaltonen, Lauri; Cazier, Jean-Baptiste; Campbell, Harry; Dunlop, Malcolm G; Houlston, Richard S

    2008-05-01

    To identify colorectal cancer (CRC) susceptibility alleles, we conducted a genome-wide association study. In phase 1, we genotyped 550,163 tagSNPs in 940 familial colorectal tumor cases (627 CRC, 313 high-risk adenoma) and 965 controls. In phase 2, we genotyped 42,708 selected SNPs in 2,873 CRC cases and 2,871 controls. In phase 3, we evaluated 11 SNPs showing association at P < 10(-4) in a joint analysis of phases 1 and 2 in 4,287 CRC cases and 3,743 controls. Two SNPs were taken forward to phase 4 genotyping (10,731 CRC cases and 10,961 controls from eight centers). In addition to the previously reported 8q24, 15q13 and 18q21 CRC risk loci, we identified two previously unreported associations: rs10795668, located at 10p14 (P = 2.5 x 10(-13) overall; P = 6.9 x 10(-12) replication), and rs16892766, at 8q23.3 (P = 3.3 x 10(-18) overall; P = 9.6 x 10(-17) replication), which tags a plausible causative gene, EIF3H. These data provide further evidence for the 'common-disease common-variant' model of CRC predisposition.

  17. Feasibility of an obesity intervention for paediatric primary care targeting parenting and children: Helping HAND.

    PubMed

    O'Connor, T M; Hilmers, A; Watson, K; Baranowski, T; Giardino, A P

    2013-01-01

      The primary care setting offers the opportunity to reach children and parents to encourage healthy lifestyle behaviours, and improve weight status among children.   Test the feasibility of Helping HAND (Healthy Activity and Nutrition Directions), an obesity intervention for 5- to 8-year-old children in primary care clinics.   A randomized controlled pilot study of Helping HAND, a 6-month intervention, targeted children with body mass index 85-99%tile and their parents. Intervention group attended monthly sessions and self-selected child behaviours and parenting practices to change. Control group received regular paediatric care and was wait-listed for Helping HAND. Session completion, participant satisfaction, child anthropometrics, dietary intake, physical activity, TV viewing and behaviour-specific parenting practices were measured pre and post intervention.   Forty parent-child dyads enrolled: 82.5% were Hispanic, 80% had a girl and 65% reported income ≤ $30, 000/year. There was 20% attrition from Helping HAND (attended <4/6 sessions). Families self-selected 4.35 (SD 1.75) behaviours to target during the 6-month programme and each of the seven behaviours was selected by 45-80% of the families. There were no between group differences in the child's body mass index z-score, dietary intake or physical activity post intervention. Intervention group viewed 14.9 (SE 2.3) h/week of TV post intervention versus control group 23.3 (SE 2.4) h/week (P < 0.05).   Helping HAND is feasible, due to low attrition, good programme attendance, and clinically relevant improvements in some child and parenting behaviours. © 2011 Blackwell Publishing Ltd.

  18. Concept of a demonstrational hybrid reactor—a tokamak with molten-salt blanket for 233U fuel production: 1. Concept of a stationary Tokamak as a neutron source

    NASA Astrophysics Data System (ADS)

    Azizov, E. A.; Gladush, G. G.; Dokuka, V. N.; Khayrutdinov, R. R.

    2015-12-01

    On the basis of current understanding of physical processes in tokamaks and taking into account engineering constraints, it is shown that a low-cost facility of a moderate size can be designed within the adopted concept. This facility makes it possible to achieve the power density of neutron flux which is of interest, in particular, for solving the problem of 233U fuel production from thorium. By using a molten-salt blanket, the important task of ensuring the safe operation of such a reactor in the case of possible coolant loss is accomplished. Moreover, in a hybrid reactor with the blanket based on liquid salts, the problem of periodic refueling that is difficult to perform in solid blankets can be solved.

  19. Measurements of cross sections and decay properties of the isotopes of elements 112, 114, and 116 produced in the fusion reactions 233,238 U , 242Pu , and 248Cm + 48Ca

    NASA Astrophysics Data System (ADS)

    Oganessian, Yu. Ts.; Utyonkov, V. K.; Lobanov, Yu. V.; Abdullin, F. Sh.; Polyakov, A. N.; Shirokovsky, I. V.; Tsyganov, Yu. S.; Gulbekian, G. G.; Bogomolov, S. L.; Gikal, B. N.; Mezentsev, A. N.; Iliev, S.; Subbotin, V. G.; Sukhov, A. M.; Voinov, A. A.; Buklanov, G. V.; Subotic, K.; Zagrebaev, V. I.; Itkis, M. G.; Patin, J. B.; Moody, K. J.; Wild, J. F.; Stoyer, M. A.; Stoyer, N. J.; Shaughnessy, D. A.; Kenneally, J. M.; Wilk, P. A.; Lougheed, R. W.; Il'Kaev, R. I.; Vesnovskii, S. P.

    2004-12-01

    We have studied the dependence of the production cross sections of the isotopes 282,283 112 and 286,287 114 on the excitation energy of the compound nuclei 286112 and 290114 . The maximum cross section values of the xn -evaporation channels for the reaction 238U ( 48Ca ,xn) 286-x 112 were measured to be σ3n = 2.5 +1.8 -1.1 pb and σ4n = 0.6 +1.6 -0.5 pb ; for the reaction 242Pu ( 48Ca ,xn) 290-x 114 : σ2n ˜0.5 pb , σ3n = 3.6 +3.4 -1.7 pb , and σ4n = 4.5 +3.6 -1.9 pb . In the reaction 233U ( 48Ca ,2 4n) 277 279 112 at E*=34.9±2.2 MeV we measured an upper cross section limit of σxn ⩽0.6 pb . The observed shift of the excitation energy associated with the maximum sum evaporation residue cross section σER (E*) to values significantly higher than that associated with the calculated Coulomb barrier can be caused by the orientation of the deformed target nucleus in the entrance channel of the reaction. An increase of σER in the reactions of actinide targets with 48Ca is consistent with the expected increase of the survivability of the excited compound nucleus upon closer approach to the closed neutron shell N=184 . In the present work we detected 33 decay chains arising in the decay of the known nuclei 282112 , 283112 , 286114 , 287114 , and 288114 . In the decay of 287114 (α) → 283112 (α) → 279110 (SF) , in two cases out of 22, we observed decay chains of four and five sequential α transitions that end in spontaneous fission of 271Sg ( Tα/SF = 2.4 +4.3 -1.0 min) and 267Rf ( TSF ˜2.3 h) , longer decay chains than reported previously. We observed the new nuclide 292116 ( Tα = 18 +16 -6 ms, Eα =10.66±0.07 MeV) in the irradiation of the 248Cm target at a higher energy than in previous experiments. The observed nuclear decay properties of the nuclides with Z=104 118 are compared with theoretical nuclear mass calculations and the systematic trends of spontaneous fission properties. As a whole, they give a consistent pattern of decay of the 18 even- Z

  20. Chemistry Lab for Phoenix Mars Lander

    NASA Image and Video Library

    2007-08-02

    The targeted landing site for NASA Phoenix Mars Lander is at about 68 degrees north latitude, 233 degrees east longitude in the Martian arctic. The Phoenix lander, which landed May 25, 2008 ceased its operations about six months later.

  1. Concept of a demonstrational hybrid reactor—a tokamak with molten-salt blanket for {sup 233}U fuel production: 1. Concept of a stationary Tokamak as a neutron source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Azizov, E. A.; Gladush, G. G., E-mail: gladush@triniti.ru; Dokuka, V. N.

    2015-12-15

    On the basis of current understanding of physical processes in tokamaks and taking into account engineering constraints, it is shown that a low-cost facility of a moderate size can be designed within the adopted concept. This facility makes it possible to achieve the power density of neutron flux which is of interest, in particular, for solving the problem of {sup 233}U fuel production from thorium. By using a molten-salt blanket, the important task of ensuring the safe operation of such a reactor in the case of possible coolant loss is accomplished. Moreover, in a hybrid reactor with the blanket basedmore » on liquid salts, the problem of periodic refueling that is difficult to perform in solid blankets can be solved.« less

  2. Design of ligand-targeted nanoparticles for enhanced cancer targeting

    NASA Astrophysics Data System (ADS)

    Stefanick, Jared F.

    Ligand-targeted nanoparticles are increasingly used as drug delivery vehicles for cancer therapy, yet have not consistently produced successful clinical outcomes. Although these inconsistencies may arise from differences in disease models and target receptors, nanoparticle design parameters can significantly influence therapeutic efficacy. By employing a multifaceted synthetic strategy to prepare peptide-targeted nanoparticles with high purity, reproducibility, and precisely controlled stoichiometry of functionalities, this work evaluates the roles of polyethylene glycol (PEG) coating, ethylene glycol (EG) peptide-linker length, peptide hydrophilicity, peptide density, and nanoparticle size on tumor targeting in a systematic manner. These parameters were analyzed in multiple disease models by targeting human epidermal growth factor receptor 2 (HER2) in breast cancer and very late antigen-4 (VLA-4) in multiple myeloma to demonstrate the widespread applicability of this approach. By increasing the hydrophilicity of the targeting peptide sequence and simultaneously optimizing the EG peptide-linker length, the in vitro cellular uptake of targeted liposomes was significantly enhanced. Specifically, including a short oligolysine chain adjacent to the targeting peptide sequence effectively increased cellular uptake ~80-fold using an EG6 peptide-linker compared to ~10-fold using an EG45 linker. In vivo, targeted liposomes prepared in a traditional manner lacking the oligolysine chain demonstrated similar biodistribution and tumor uptake to non-targeted liposomes. However, by including the oligolysine chain, targeted liposomes using an EG45 linker significantly improved tumor uptake ~8-fold over non-targeted liposomes, while the use of an EG6 linker decreased tumor accumulation and uptake, owing to differences in cellular uptake kinetics, clearance mechanisms, and binding site barrier effects. To further improve tumor targeting and enhance the selectivity of targeted

  3. Preliminary results of calculations for heavy-water nuclear-power-plant reactors employing 235U, 233U, and 232Th as a fuel and meeting requirements of a nonproliferation of nuclear weapons

    NASA Astrophysics Data System (ADS)

    Ioffe, B. L.; Kochurov, B. P.

    2012-02-01

    A physical design is developed for a gas-cooled heavy-water nuclear reactor intended for a project of a nuclear power plant. As a fuel, the reactor would employ thorium with a small admixture of enriched uranium that contains not more than 20% of 235U. It operates in the open-cycle mode involving 233U production from thorium and its subsequent burnup. The reactor meets the conditions of a nonproliferation of nuclear weapons: the content of fissionable isotopes in uranium at all stages of the process, including the final one, is below the threshold for constructing an atomic bomb, the amount of product plutonium being extremely small.

  4. SuperTarget goes quantitative: update on drug–target interactions

    PubMed Central

    Hecker, Nikolai; Ahmed, Jessica; von Eichborn, Joachim; Dunkel, Mathias; Macha, Karel; Eckert, Andreas; Gilson, Michael K.; Bourne, Philip E.; Preissner, Robert

    2012-01-01

    There are at least two good reasons for the on-going interest in drug–target interactions: first, drug-effects can only be fully understood by considering a complex network of interactions to multiple targets (so-called off-target effects) including metabolic and signaling pathways; second, it is crucial to consider drug-target-pathway relations for the identification of novel targets for drug development. To address this on-going need, we have developed a web-based data warehouse named SuperTarget, which integrates drug-related information associated with medical indications, adverse drug effects, drug metabolism, pathways and Gene Ontology (GO) terms for target proteins. At present, the updated database contains >6000 target proteins, which are annotated with >330 000 relations to 196 000 compounds (including approved drugs); the vast majority of interactions include binding affinities and pointers to the respective literature sources. The user interface provides tools for drug screening and target similarity inclusion. A query interface enables the user to pose complex queries, for example, to find drugs that target a certain pathway, interacting drugs that are metabolized by the same cytochrome P450 or drugs that target proteins within a certain affinity range. SuperTarget is available at http://bioinformatics.charite.de/supertarget. PMID:22067455

  5. Uranium series dating of human skeletal remains from the Del Mar and Sunnyvale sites, California

    USGS Publications Warehouse

    Bischoff, J.L.; Rosenbauer, R.J.

    1981-01-01

    Uranium series analyses of human bone samples from the Del Mar and Sunnyvale sites indicate ages of 11,000 and 8,300 years, respectively. The dates are supported by internal concordancy between thorium-230 and protactinium-231 decay systems. These ages are significantly younger than the estimates of 48,000 and 70,000 years based on amino acid racemization, and indicate that the individuals could derive from the population waves that came across the Bering Strait during the last sea-level low. Copyright ?? 1981 AAAS.

  6. Attentional Control via Parallel Target-Templates in Dual-Target Search

    PubMed Central

    Barrett, Doug J. K.; Zobay, Oliver

    2014-01-01

    Simultaneous search for two targets has been shown to be slower and less accurate than independent searches for the same two targets. Recent research suggests this ‘dual-target cost’ may be attributable to a limit in the number of target-templates than can guide search at any one time. The current study investigated this possibility by comparing behavioural responses during single- and dual-target searches for targets defined by their orientation. The results revealed an increase in reaction times for dual- compared to single-target searches that was largely independent of the number of items in the display. Response accuracy also decreased on dual- compared to single-target searches: dual-target accuracy was higher than predicted by a model restricting search guidance to a single target-template and lower than predicted by a model simulating two independent single-target searches. These results are consistent with a parallel model of dual-target search in which attentional control is exerted by more than one target-template at a time. The requirement to maintain two target-templates simultaneously, however, appears to impose a reduction in the specificity of the memory representation that guides search for each target. PMID:24489793

  7. Is targeted fortification of human breast milk an optimal nutrition strategy for preterm infants? An interventional study.

    PubMed

    Morlacchi, Laura; Mallardi, Domenica; Giannì, Maria Lorella; Roggero, Paola; Amato, Orsola; Piemontese, Pasqua; Consonni, Dario; Mosca, Fabio

    2016-07-01

    Fortifying human milk contributes to the prevention of postnatal growth failure in preterm infants. Because of the natural variability of human milk, targeted fortification of human milk has been advocated. However, data regarding the efficacy and safety of prolonged targeted fortification are scarce. We aimed to assess the safety of targeted fortification of human milk in preterm infants compared with standard fortification, as well as the effects on infant growth. We conducted an interventional study during hospital stay in healthy very low birth weight preterm infants who were exclusively fed human milk. Pools of human milk collected for 24 h were analysed using mid-infrared transmission spectroscopy. Targeted fortification of human milk was performed by adding macronutrients to native human milk to obtain optimal ratios of fat (4.4 g), carbohydrates (8.8 g), and protein (3 g) per 100 ml. The intervention period lasted 4-7 weeks. Weekly weight and daily growth rates were compared with those of a standardized fortification group of very low birth weight preterm infants who received standard fortified human milk (n = 10). The osmolality as well as the metabolic and gastrointestinal tolerance were monitored. Intergroup differences were evaluated using the Mann-Whitney U-test. A total of 10 preterm infants (birth weight 1223 ± 195 g; gestational age 29.1 ± 1.03 weeks) were enrolled and 118 samples of pooled milk were analysed. On average, 1.4 ± 0.1 g of protein, 2.3 ± 0.5 g of carbohydrate, and 0.3 ± 0.1 g of fat per 100 ml were added to the milk. Osmolality values after target fortification were within recommended limits (376 ± 66 mOsml/kg). Weekly weight gain (205.5 g; 95 % CI 177-233 vs 155 g; 95 % CI 132-178; p = 0.025) and daily growth rates (15.7 g/kg/day; 95 % CI 14.5-16.9 vs 12.3 g/kg/day; 95 % CI 10.7-13.9; p = 0.005) were higher in infants receiving target fortification than in infants receiving standardized

  8. Tumor-targeted polymeric nanostructured lipid carriers with precise ratiometric control over dual-drug loading for combination therapy in non-small-cell lung cancer.

    PubMed

    Liang, Yan; Tian, Baocheng; Zhang, Jing; Li, Keke; Wang, Lele; Han, Jingtian; Wu, Zimei

    2017-01-01

    Gemcitabine (GEM) and paclitaxel (PTX) are effective combination anticancer agents against non-small-cell lung cancer (NSCLC). At the present time, a main challenge of combination treatment is the precision of control that will maximize the combined effects. Here, we report a novel method to load GEM (hydrophilic) and PTX (hydrophobic) into simplex tumor-targeted nanostructured lipid carriers (NLCs) for accurate control of the ratio of the two drugs. We covalently preconjugated the dual drugs through a hydrolyzable ester linker to form drug conjugates. N -acetyl-d-glucosamine (NAG) is a glucose receptor-targeting ligand. We added NAG to the formation of NAG-NLCs. In general, synthesis of poly(6- O -methacryloyl-d-galactopyranose)-GEM/PTX (PMAGP-GEM/PTX) conjugates was demonstrated, and NAG-NLCs were prepared using emulsification and solvent evaporation. NAG-NLCs displayed sphericity with an average diameter of 120.3±1.3 nm, a low polydispersity index of 0.233±0.04, and accurate ratiometric control over the two drugs. A cytotoxicity assay showed that the NAG-NLCs had better antitumor activity on NSCLC cells than normal cells. There was an optimal ratio of the two drugs, exhibiting the best cytotoxicity and combinatorial effects among all the formulations we tested. In comparison with both the free-drug combinations and separately nanopackaged drug conjugates, PMAGP-GEM/PTX NAG-NLCs (3:1) exhibited superior synergism. Flow cytometry and confocal laser scanning microscopy showed that NAG-NLCs exhibited higher uptake efficiency in A549 cells via glucose receptor-mediated endocytosis. This combinatorial delivery system settles problems with ratiometric coloading of hydrophilic and hydrophobic drugs for tumor-targeted combination therapy to achieve maximal anticancer efficacy in NSCLC.

  9. On the Nature of the Cherdyntsev-Chalov Effect

    NASA Astrophysics Data System (ADS)

    Timashev, S. F.

    2018-06-01

    It is shown that the Cherdyntsev-Chalov effect, usually presented as the separation of even isotopes of uranium upon their transition from the solid to the liquid phase, can include initiated acceleration of the radioactive decay of uranium-238 nuclei during the formation of cracks in geologically (seismic and volcanically) active zones of the Earth's crust. The fissuring of the solid-phase medium leads to an increase in mechanical tensile stress and the emergence of strong local electric fields, resulting in the injection of chemical-scale high-energy electrons into the aqueous phase of the cracks. Under these conditions, the e - catalytic decay of uranium-238 nucleus studied earlier can occur during the formation of metastable protactinium-238 nuclei with locally distorted nucleon structure, which subequently undergo β-decay with the formation of thorium-234 and helium-4 nuclei as products of the fission of the initial uranium-238 nucleus with a characteristic period of several years. The observed increased activity of uranium-234 nuclei that form during the subsequent β-decay of thorium and then protactinium is associated with the initiated fission of uranium-238. The possibility is discussed of developing thermal power by using existing wastes from uranium production that contain uranium-238 to activate this isotope through the mechanochemical processing of these wastes in aqueous media with the formation of 91 238 Pa isu , the half-life of which is several years.

  10. Full and home smoking ban adoption after a randomized controlled trial targeting secondhand smoke exposure reduction.

    PubMed

    Nicholson, Jody S; McDermott, Michael J; Huang, Qinlei; Zhang, Hui; Tyc, Vida L

    2015-05-01

    The current study examined home and full (i.e., home plus car) smoking ban adoption as secondary outcomes to a randomized controlled trial targeting reduced secondhand smoke exposure (SHSe) for children under treatment for cancer. Families with at least 1 adult smoker who reported SHSe for their children (n = 119) were randomized to control or intervention conditions and followed for 1 year with 5 assessments. Both groups were advised of the negative health outcomes associated with SHSe; the intervention group provided more in-depth counseling from baseline to 3 months. Parents reported on household and car smoking behavior, demographic, psychosocial, and medical/treatment-related information. Regardless of group assignment, there was an increase in home (odds ration [OR] = 1.16, p = .074) and full (OR = 1.37, p = .001) smoking ban adoption across time. Families in the intervention group were more likely to adopt a full ban by 3 months, but this difference was nonsignificant by 12 months. Married parents (OR = 2.33, p = .006) and those with higher self-efficacy for controlling children's SHSe (OR = 1.11, p = .023) were more likely to have a home smoking ban; parents who reported smoking fewer cigarettes were more likely to adopt a home (OR = 1.62, p < .0001) or full (OR = 7.32, p = .038) ban. Smoking bans are in-line with Healthy People 2020's tobacco objectives and may be more feasible for parents with medically compromised children for immediate SHSe reduction. Furthermore, interventions targeting full smoking bans may be a more effective for comprehensive elimination of SHSe. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco 2014. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  11. PROCESS FOR DECONTAMINATING THORIUM AND URANIUM WITH RESPECT TO RUTHENIUM

    DOEpatents

    Meservey, A.A.; Rainey, R.H.

    1959-10-20

    The control of ruthenium extraction in solvent-extraction processing of neutron-irradiated thorium is presented. Ruthenium is rendered organic-insoluble by the provision of sulfite or bisulfite ions in the aqueous feed solution. As a result the ruthenium remains in the aqueous phase along with other fission product and protactinium values, thorium and uranium values being extracted into the organic phase. This process is particularly applicable to the use of a nitrate-ion-deficient aqueous feed solution and to the use of tributyl phosphate as the organic extractant.

  12. Open Targets: a platform for therapeutic target identification and validation

    PubMed Central

    Koscielny, Gautier; An, Peter; Carvalho-Silva, Denise; Cham, Jennifer A.; Fumis, Luca; Gasparyan, Rippa; Hasan, Samiul; Karamanis, Nikiforos; Maguire, Michael; Papa, Eliseo; Pierleoni, Andrea; Pignatelli, Miguel; Platt, Theo; Rowland, Francis; Wankar, Priyanka; Bento, A. Patrícia; Burdett, Tony; Fabregat, Antonio; Forbes, Simon; Gaulton, Anna; Gonzalez, Cristina Yenyxe; Hermjakob, Henning; Hersey, Anne; Jupe, Steven; Kafkas, Şenay; Keays, Maria; Leroy, Catherine; Lopez, Francisco-Javier; Magarinos, Maria Paula; Malone, James; McEntyre, Johanna; Munoz-Pomer Fuentes, Alfonso; O'Donovan, Claire; Papatheodorou, Irene; Parkinson, Helen; Palka, Barbara; Paschall, Justin; Petryszak, Robert; Pratanwanich, Naruemon; Sarntivijal, Sirarat; Saunders, Gary; Sidiropoulos, Konstantinos; Smith, Thomas; Sondka, Zbyslaw; Stegle, Oliver; Tang, Y. Amy; Turner, Edward; Vaughan, Brendan; Vrousgou, Olga; Watkins, Xavier; Martin, Maria-Jesus; Sanseau, Philippe; Vamathevan, Jessica; Birney, Ewan; Barrett, Jeffrey; Dunham, Ian

    2017-01-01

    We have designed and developed a data integration and visualization platform that provides evidence about the association of known and potential drug targets with diseases. The platform is designed to support identification and prioritization of biological targets for follow-up. Each drug target is linked to a disease using integrated genome-wide data from a broad range of data sources. The platform provides either a target-centric workflow to identify diseases that may be associated with a specific target, or a disease-centric workflow to identify targets that may be associated with a specific disease. Users can easily transition between these target- and disease-centric workflows. The Open Targets Validation Platform is accessible at https://www.targetvalidation.org. PMID:27899665

  13. X-ray powder diffraction, spectroscopic study, dielectric properties and thermal analysis of new doped compound TiGa0.67Te2.33O8

    NASA Astrophysics Data System (ADS)

    Smaoui, S.; Ben Aribia, W.; Kabadou, A.; Abdelmouleh, M.

    2017-04-01

    A novel mixed valence tellurium oxide, TiGa0.67Te2.33O8, was synthesized and its crystal structure determined using the X-ray powder diffraction technique. The obtained oxide was found to crystallize in a cubic unit-cell, Ia 3 bar space group, with the lattice parameter a = 10.9557(1) Å. Rietveld refinement of the structure led to ultimate confidence factors Rp = 7.63 and Rwp = 6.71. This structure was based on slabs containing groups of (Te/Ga)O4 joined by the metal cations Ti4+. The structure analysis showed a cation ordering of Te4+ and Te6+ yielding a TiGa2/3Te7/3O8 formula. The IR and RAMAN spectra confirmed the presence of the TiO6 and (Te/Ga)O4 groups. The dielectric anomalies observed at 500 K were attributed to the mixed valence structure, arising from the mixed-valence Te6+/Te4+. We detected only one peak in thermal behavior by the DTA/TG analysis; which implied a melting reaction.

  14. Flexible synthesis of poison-frog alkaloids of the 5,8-disubstituted indolizidine-class. II: Synthesis of (-)-209B, (-)-231C, (-)-233D, (-)-235B", (-)-221I, and an epimer of 193E and pharmacological effects at neuronal nicotinic acetylcholine receptors.

    PubMed

    Kobayashi, Soushi; Toyooka, Naoki; Zhou, Dejun; Tsuneki, Hiroshi; Wada, Tsutomu; Sasaoka, Toshiyasu; Sakai, Hideki; Nemoto, Hideo; Garraffo, H Martin; Spande, Thomas F; Daly, John W

    2007-01-01

    The 5,8-disubstituted indolizidines constitute the largest class of poison-frog alkaloids. Some alkaloids have been shown to act as noncompetitive blockers at nicotinic acetylcholine receptors but the proposed structures and the biological activities of most of the 5,8-disubstituted indolizidines have not been determined because of limited supplies of the natural products. We have therefore conducted experiments to confirm proposed structures and determine biological activities using synthetic compounds. Recently, we reported that one of this class of alkaloids, (-)-235B', acts as a noncompetitive antagonist for α4β2 nicotinic receptors, and its sensitivity is comparable to that of the classical competitive antagonist for this receptor, dihydro-β-erythroidine. The enantioselective syntheses of (-)-209B, (-)-231C, (-)-233D, (-)-235B", (-)-221I, and what proved to be an epimer of natural 193E, starting from common chiral lactams have been achieved. When we performed electrophysiological recordings to examine the effects of the synthetic alkaloids on two major subtypes of nicotinic receptors (α4β2 and α7) expressed in Xenopus laevis oocytes, (-)-231C effectively blocked α4β2 receptor responses (IC(50 )value, 1.5 μM) with a 7.0-fold higher potency than for blockade of α7 receptor responses. In contrast, synthetic (-)-221I and (-)-epi-193E were more potent in blocking α7 receptor responses (IC(50 )value, 4.4 μM and 9.1 μM, respectively) than α4β2 receptor responses (5.3-fold and 2.0-fold, respectively). We achieved the total synthesis of (-)-209B, (-)-231C, (-)-233D, (-)-235B", (-)-221I, and an epimer of 193E starting from common chiral lactams, and the absolute stereochemistry of natural (-)-233D was determined. Furthermore, the relative stereochemistry of (-)-231C and (-)-221I was also determined. The present asymmetric synthesis of the proposed structure for 193E revealed that the C-8 configuration of natural 193E should be revised. The selectivity for

  15. Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing

    PubMed Central

    Lee, Ciaran M; Cradick, Thomas J; Fine, Eli J; Bao, Gang

    2016-01-01

    The rapid advancement in targeted genome editing using engineered nucleases such as ZFNs, TALENs, and CRISPR/Cas9 systems has resulted in a suite of powerful methods that allows researchers to target any genomic locus of interest. A complementary set of design tools has been developed to aid researchers with nuclease design, target site selection, and experimental validation. Here, we review the various tools available for target selection in designing engineered nucleases, and for quantifying nuclease activity and specificity, including web-based search tools and experimental methods. We also elucidate challenges in target selection, especially in predicting off-target effects, and discuss future directions in precision genome editing and its applications. PMID:26750397

  16. Literature evidence in open targets - a target validation platform.

    PubMed

    Kafkas, Şenay; Dunham, Ian; McEntyre, Johanna

    2017-06-06

    We present the Europe PMC literature component of Open Targets - a target validation platform that integrates various evidence to aid drug target identification and validation. The component identifies target-disease associations in documents and ranks the documents based on their confidence from the Europe PMC literature database, by using rules utilising expert-provided heuristic information. The confidence score of a given document represents how valuable the document is in the scope of target validation for a given target-disease association by taking into account the credibility of the association based on the properties of the text. The component serves the platform regularly with the up-to-date data since December, 2015. Currently, there are a total number of 1168365 distinct target-disease associations text mined from >26 million PubMed abstracts and >1.2 million Open Access full text articles. Our comparative analyses on the current available evidence data in the platform revealed that 850179 of these associations are exclusively identified by literature mining. This component helps the platform's users by providing the most relevant literature hits for a given target and disease. The text mining evidence along with the other types of evidence can be explored visually through https://www.targetvalidation.org and all the evidence data is available for download in json format from https://www.targetvalidation.org/downloads/data .

  17. Study of target and non-target interplay in spatial attention task.

    PubMed

    Sweeti; Joshi, Deepak; Panigrahi, B K; Anand, Sneh; Santhosh, Jayasree

    2018-02-01

    Selective visual attention is the ability to selectively pay attention to the targets while inhibiting the distractors. This paper aims to study the targets and non-targets interplay in spatial attention task while subject attends to the target object present in one visual hemifield and ignores the distractor present in another visual hemifield. This paper performs the averaged evoked response potential (ERP) analysis and time-frequency analysis. ERP analysis agrees to the left hemisphere superiority over late potentials for the targets present in right visual hemifield. Time-frequency analysis performed suggests two parameters i.e. event-related spectral perturbation (ERSP) and inter-trial coherence (ITC). These parameters show the same properties for the target present in either of the visual hemifields but show the difference while comparing the activity corresponding to the targets and non-targets. In this way, this study helps to visualise the difference between targets present in the left and right visual hemifields and, also the targets and non-targets present in the left and right visual hemifields. These results could be utilised to monitor subjects' performance in brain-computer interface (BCI) and neurorehabilitation.

  18. LIQUID TARGET

    DOEpatents

    Martin, M.D.; Salsig, W.W. Jr.

    1959-01-13

    A liquid handling apparatus is presented for a liquid material which is to be irradiated. The apparatus consists essentially of a reservoir for the liquid, a target element, a drain tank and a drain lock chamber. The target is in the form of a looped tube, the upper end of which is adapted to be disposed in a beam of atomic particles. The lower end of the target tube is in communication with the liquid in the reservoir and a means is provided to continuously circulate the liquid material to be irradiated through the target tube. Means to heat the reservoir tank is provided in the event that a metal is to be used as the target material. The apparatus is provided with suitable valves and shielding to provide maximum safety in operation.

  19. Efficacy of dialysis in peritoneal dialysis: utility of bioimpedance to calculate Kt/V and the search for a target Kt.

    PubMed

    Martínez Fernández, G; Ortega Cerrato, A; Masiá Mondéjar, J; Pérez Rodríguez, A; Llamas Fuentes, F; Gómez Roldán, C; Pérez-Martínez, Juan

    2013-04-01

    To calculate Kt/V, volume (V) is usually obtained by Watson formula, but bioimpedance spectroscopy (BIS) is a simple and applicable technique to determinate V, along with other hydration and nutrition parameters, in peritoneal dialysis (PD) patients. Dialysis efficacy can also be measured with Kt, but no experience exists in PD, so there is no reference/target value for Kt that must be achieved in these patients to be considered adequately dialyzed. We evaluated the efficacy of PD with Kt/V using Watson formula and BIS for V calculation, assessed hydration status in a PD unit by data obtained by BIS, and attempted to find a reference Kt from the Kt/V previously obtained by BIS. In this observational prospective study of 78 PD patients, we measured V using BIS (V bis) and Watson formula (V w) and calculated weekly Kt/V using both volumes (Kt/V bis/V bis and Kt/V w). With the BIS technique, we obtained and subsequently analyzed other hydration status parameters. We achieved a reference Kt, extrapolating the value desired (weekly Kt/V 1.7) to the target Kt using the simple linear regression statistical technique, basing it on the results of the previously calculated Pearson's linear correlation coefficient. Volume was 1.8 l higher by Watson formula than with BIS (p < 0.001). Weekly Kt/V bis was 2.33 ± 0.68, and mean weekly Kt/V w was 2.20 ± 0.63 (p < 0.0001); 60.25 % of patients presented overhydration according to the BIS study (OH >1.1 l). The target value of Kt for the reference weekly Kt/V bis (1.7) was 64.87 l. BIS is a simple, applicable technique for calculating V in dialysis that can be especially useful in PD patients compared with the anthropometric formulas, by the abnormally distributed body water in these patients. Other parameters obtained by BIS will serve to assess both the distribution of body volume and nutritional status in the clinical setting. The target Kt value obtained from Kt/V bis allowed us to measure the efficacy of PD in a practical way

  20. Preliminary evidence for linkage to chromosome 1q31-32, 10q23.3, and 16p13.3 in a South African cohort with bipolar disorder.

    PubMed

    Savitz, Jonathan; Cupido, Cinda-Lee; Ramesar, Raj Kumar

    2007-04-05

    Although the genetic variants predisposing to the development of bipolar disorder (BPD) have yet to be conclusively identified, replicated reports of linkage to particular chromosomal regions have been encouraging. Here we carried out a non-parametric linkage analysis of nine of these candidate loci in a unique South African sample of 47 BPD pedigrees (N = 350). Three polymorphic markers per region of interest (3 x 9) were typed in a Caucasian cohort of Afrikaner and British origin. Statistically significant evidence for linkage was obtained at 1q31-32, 10q23.3, and 16p13.3 with maximum NPL scores of 2.52, 2.01, and 1.84, respectively. Our results add to the growing evidence that these chromosomal regions harbor genetic variants that play a role in the development of bipolar spectrum illness. Negative results were obtained for the remaining six candidate loci, possibly due to limited statistical power. (c) 2006 Wiley-Liss, Inc.

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