Sample records for protein 54k bcp54

  1. DCM-related tropomyosin mutants E40K/E54K over-inhibit the actomyosin interaction and lead to a decrease in the number of cycling cross-bridges.

    PubMed

    Bai, Fan; Groth, Heather L; Kawai, Masataka

    2012-01-01

    Two DCM mutants (E40K and E54K) of tropomyosin (Tm) were examined using the thin-filament extraction/reconstitu-tion technique. The effects of the Ca²⁺, ATP, phos-phate (Pi), and ADP concentrations on isometric tension and its transients were studied at 25°C, and the results were com-pared to those for the WT protein. Our results indicate that both E40K and E54K have a significantly lower T(HC) (high Ca²⁺ ten-sion at pCa 4.66) (E40K: 1.21±0.06 T(a), ±SEM, N = 34; E54K: 1.24±0.07 T(a), N = 28), a significantly lower T(LC) (low- Ca²⁺ tension at pCa 7.0) (E40K: 0.07±0.02 T(a), N = 34; E54K: 0.06±0.02 T(a), N = 28), and a significantly lower T(act) (Ca²⁺ activatable tension) (T(act) = T(HC)-T(LC,) E40K: 1.15±0.08 T(a), N = 34; E54K: 1.18±0.06 T(a), N = 28) than WT (T(HC) = 1.53±0.07 T(a), T(LC) = 0.12±0.01 T(a), T(act) = 1.40±0.07 T(a), N = 25). All tensions were normalized to T(a) ( = 13.9±0.8 kPa, N = 57), the ten-sion of actin-filament reconstituted cardiac fibers (myocardium) under the standard activating conditions. The Ca²⁺ sensitivity (pCa₅₀) of E40K (5.23±0.02, N = 34) and E54K (5.24±0.03, N = 28) was similar to that of the WT protein (5.26±0.03, N = 25). The cooper-a-tivity increased significantly in E54K (3.73±0.25, N = 28) compared to WT (2.80±0.17, N = 25). Seven kinetic constants were deduced using sinusoidal analysis at pCa 4.66. These results enabled us to calculate the cross-bridge distribution in the strongly attached states, and thereby deduce the force/cross-bridge. The results indicate that the force/cross-bridge is ∼15% less in E54K than WT, but remains similar to that of the WT protein in the case of E40K. We conclude that over-inhibition of the actomyosin interaction by E40K and E54K Tm mutants leads to a decreased force-generating ability at systole, which is the main mechanism underlying the early pathogenesis of DCM.

  2. iPro54-PseKNC: a sequence-based predictor for identifying sigma-54 promoters in prokaryote with pseudo k-tuple nucleotide composition

    PubMed Central

    Lin, Hao; Deng, En-Ze; Ding, Hui; Chen, Wei; Chou, Kuo-Chen

    2014-01-01

    The σ54 promoters are unique in prokaryotic genome and responsible for transcripting carbon and nitrogen-related genes. With the avalanche of genome sequences generated in the postgenomic age, it is highly desired to develop automated methods for rapidly and effectively identifying the σ54 promoters. Here, a predictor called ‘iPro54-PseKNC’ was developed. In the predictor, the samples of DNA sequences were formulated by a novel feature vector called ‘pseudo k-tuple nucleotide composition’, which was further optimized by the incremental feature selection procedure. The performance of iPro54-PseKNC was examined by the rigorous jackknife cross-validation tests on a stringent benchmark data set. As a user-friendly web-server, iPro54-PseKNC is freely accessible at http://lin.uestc.edu.cn/server/iPro54-PseKNC. For the convenience of the vast majority of experimental scientists, a step-by-step protocol guide was provided on how to use the web-server to get the desired results without the need to follow the complicated mathematics that were presented in this paper just for its integrity. Meanwhile, we also discovered through an in-depth statistical analysis that the distribution of distances between the transcription start sites and the translation initiation sites were governed by the gamma distribution, which may provide a fundamental physical principle for studying the σ54 promoters. PMID:25361964

  3. Two T7-like Bacteriophages, K5-2 and K5-4, Each Encodes Two Capsule Depolymerases: Isolation and Functional Characterization.

    PubMed

    Hsieh, Pei-Fang; Lin, Hsiao-Hsuan; Lin, Tzu-Lung; Chen, Yi-Yin; Wang, Jin-Town

    2017-07-04

    Two Klebsiella bacteriophages K5-2 and K5-4, which are able to infect and grow on either capsular types K30/K69 and K5 or K8 and K5 of Klebsiella strains, were isolated and characterized. Each phage contained two open reading frames (ORFs), which encoded two putative capsule depolymerases, respectively. The first ORF encoded tail fiber proteins, which have K30/K69 depolymerase and K8 depolymerase activities. The second ORF encoded hypothetical proteins, which are almost identical in amino acid sequences, and have K5 depolymerase activity. Alcian blue staining of enzyme-treated capsular polysaccharides (CPS) showed that purified depolymerases can cleave purified Klebsiella CPS in vitro and liberate monosaccharaides. Capsule K5 deletion mutants were not lysed by either phage, suggesting that the capsule was essential for phage infection. Bacterial killing was observed when incubated Klebsiella strains with phages but not with purified depolymerases. Treatment with the K5-4 phage significantly increased the survival of mice infected with a K. pneumoniae K5 strain. In conclusion, two dual host-specific Klebsiella phages and their tailspikes exhibit capsule depolymerase activity were characterized. Each phage and phage-encoded depolymerase has specificity for capsular type K30/K69, K8 or K5, and could be used for the typing and treatment of K. pneumoniae infection.

  4. /sup 54/Mn absorption and excretion in rats fed soy protein and casein diets

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, D.Y.; Johnson, P.E.

    1989-02-01

    Rats were fed diets containing either soy protein or casein and different levels of manganese, methionine, phytic acid, or arginine for 7 days and then fed test meals labeled with 2 microCi of 54Mn after an overnight fast. Retention of 54Mn in each rat was measured every other day for 21 days using a whole-body counter. Liver manganese was higher (P less than 0.0001) in soy protein-fed rats (8.8 micrograms/g) than in casein-fed rats (5.2 micrograms/g); manganese superoxide dismutase activity also was higher in soy protein-fed rats than in casein-fed rats (P less than 0.01). There was a significant interactionmore » between manganese and protein which affected manganese absorption and biologic half-life of 54Mn. In a second experiment, rats fed soy protein-test meals retained more 54Mn (P less than 0.001) than casein-fed rats. Liver manganese (8.3 micrograms/g) in the soy protein group was also higher than that (5.7 micrograms/g) in the casein group (P less than 0.0001), but manganese superoxide dismutase activity was unaffected by protein. Supplementation with methionine increased 54Mn retention from both soy and casein diets (P less than 0.06); activity of manganese superoxide dismutase increased (P less than 0.05) but liver manganese did not change. The addition of arginine to casein diets had little effect on manganese bioavailability. Phytic acid affected neither manganese absorption nor biologic half-life in two experiments, but it depressed liver manganese in one experiment. These results suggest that neither arginine nor phytic acid was the component in soy protein which made manganese more available from soy protein diets than casein diets.« less

  5. Tyrosine Residues Regulate Multiple Nuclear Functions of P54nrb.

    PubMed

    Lee, Ahn R; Hung, Wayne; Xie, Ning; Liu, Liangliang; He, Leye; Dong, Xuesen

    2017-04-01

    The non-POU-domain-containing octamer binding protein (NONO; also known as p54nrb) has various nuclear functions ranging from transcription, RNA splicing, DNA synthesis and repair. Although tyrosine phosphorylation has been proposed to account for the multi-functional properties of p54nrb, direct evidence on p54nrb as a phosphotyrosine protein remains unclear. To investigate the tyrosine phosphorylation status of p54nrb, we performed site-directed mutagenesis on the five tyrosine residues of p54nrb, replacing the tyrosine residues with phenylalanine or alanine, and immunoblotted for tyrosine phosphorylation. We then preceded with luciferase reporter assays, RNA splicing minigene assays, co-immunoprecipitation, and confocal microscopy to study the function of p54nrb tyrosine residues on transcription, RNA splicing, protein-protein interaction, and cellular localization. We found that p54nrb was not phosphorylated at tyrosine residues. Rather, it has non-specific binding affinity to anti-phosphotyrosine antibodies. However, replacement of tyrosine with phenylalanine altered p54nrb activities in transcription co-repression and RNA splicing in gene context-dependent fashions by means of differential regulation of p54nrb protein association with its interacting partners and co-regulators of transcription and splicing. These results demonstrate that tyrosine residues, regardless of phosphorylation status, are important for p54nrb function. J. Cell. Physiol. 232: 852-861, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  6. Expression of recombinant sea urchin cellulase SnEG54 using mammalian cell lines.

    PubMed

    Okumura, Fumihiko; Kameda, Hiroyuki; Ojima, Takao; Hatakeyama, Shigetsugu

    2010-05-07

    We previously identified the cellulase SnEG54 from Japanese purple sea urchin Strongylocentrotus nudus, the molecular mass of which is about 54kDa on SDS-PAGE. It is difficult to express and purify a recombinant cellulase protein using bacteria such as Escherichia coli or yeast. In this study, we generated mammalian expression vectors encoding SnEG54 to transiently express SnEG54 in mammalian cells. Both SnEG54 expressed in mammalian cells and SnEG54 released into the culture supernatant showed hydrolytic activity toward carboxymethyl cellulose. By using a retroviral expression system, we also established a mammalian cell line that constitutively produces SnEG54. Unexpectedly, SnEG54 released into the culture medium was not stable, and the peak time showing the highest concentration was approximately 1-2days after seeding into fresh culture media. These findings suggest that non-mammalian sea urchin cellulase can be generated in human cell lines but that recombinant SnEG54 is unstable in culture medium due to an unidentified mechanism. Copyright (c) 2010 Elsevier Inc. All rights reserved.

  7. High statistics search for the θ+(1.54) pentaquark state

    NASA Astrophysics Data System (ADS)

    Longo, M. J.; Burnstein, R. A.; Chakravorty, A.; Chen, Y. C.; Choong, W. S.; Clark, K.; Dukes, E. C.; Durandet, C.; Felix, J.; Fu, Y.; Gidal, G.; Gustafson, H. R.; Holmstrom, T.; Huang, M.; James, C.; Jenkins, C. M.; Jones, T.; Kaplan, D. M.; Lederman, L. M.; Leros, N.; Lopez, F.; Lu, L. C.; Luebke, W.; Luk, K. B.; Nelson, K. S.; Park, H. K.; Perroud, J.-P.; Rajaram, D.; Rubin, H. A.; Volk, J.; White, C. G.; White, S.; Zyla, P.

    2004-12-01

    We have searched for θ+(1.54)→K0p decays using data from the 1999 run of the HyperCP experiment at Fermilab. We see no evidence for a narrow peak in the K0Sp mass distribution near 1.54 GeV/c among 106 000 K0Sp candidates, and obtain an upper limit for the fraction of θ+(1.54) to K0Sp candidates of <0.3% at 90% confidence.

  8. Characterization of molecular determinants for nucleocytoplasmic shuttling of PRV UL54

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li Meili; Wang Shuai; Cai Mingsheng

    2011-09-01

    The pseudorabies virus (PRV) early protein UL54 is a homologue of the herpes simplex virus 1 (HSV-1) immediate-early protein ICP27, which is a multifunctional protein and essential for HSV-1 infection. To determine if UL54 might shuttle between the nucleus and cytoplasm, as has been shown for its homologues in human herpesviruses, the molecular determinants for its nucleocytoplasmic shuttling were investigated. Heterokaryon assays demonstrated that UL54 was a nucleocytoplasmic shuttling protein and this property could not be blocked by leptomycin B, an inhibitor of chromosome region maintenance 1 (CRM1). However, TAP/NXF1 promoted the nuclear export of UL54 and interacted with UL54,more » suggesting that UL54 shuttles between the nucleus and the cytoplasm via a TAP/NXF1, but not CRM1, dependent nuclear export pathway. Furthermore, UL54 was demonstrated to target to the nucleus through a classic Ran-, importin {beta}1- and {alpha}5-dependent nuclear import mechanism.« less

  9. Expansion of divergent SEA domains in cell surface proteins and nucleoporin 54.

    PubMed

    Pei, Jimin; Grishin, Nick V

    2017-03-01

    SEA (sea urchin sperm protein, enterokinase, agrin) domains, many of which possess autoproteolysis activity, have been found in a number of cell surface and secreted proteins. Despite high sequence divergence, SEA domains were also proposed to be present in dystroglycan based on a conserved autoproteolysis motif and receptor-type protein phosphatase IA-2 based on structural similarity. The presence of a SEA domain adjacent to the transmembrane segment appears to be a recurring theme in quite a number of type I transmembrane proteins on the cell surface, such as MUC1, dystroglycan, IA-2, and Notch receptors. By comparative sequence and structural analyses, we identified dystroglycan-like proteins with SEA domains in Capsaspora owczarzaki of the Filasterea group, one of the closest single-cell relatives of metazoans. We also detected novel and divergent SEA domains in a variety of cell surface proteins such as EpCAM, α/ε-sarcoglycan, PTPRR, collectrin/Tmem27, amnionless, CD34, KIAA0319, fibrocystin-like protein, and a number of cadherins. While these proteins are mostly from metazoans or their single cell relatives such as choanoflagellates and Filasterea, fibrocystin-like proteins with SEA domains were found in several other eukaryotic lineages including green algae, Alveolata, Euglenozoa, and Haptophyta, suggesting an ancient evolutionary origin. In addition, the intracellular protein Nucleoporin 54 (Nup54) acquired a divergent SEA domain in choanoflagellates and metazoans. © 2016 The Protein Society.

  10. Functional conservation of the yeast and Arabidopsis RAD54-like genes.

    PubMed

    Klutstein, Michael; Shaked, Hezi; Sherman, Amir; Avivi-Ragolsky, Naomi; Shema, Efrat; Zenvirth, Drora; Levy, Avraham A; Simchen, Giora

    2008-04-01

    The Saccharomyces cerevisiae RAD54 gene has critical roles in DNA double-strand break repair, homologous recombination, and gene targeting. Previous results show that the yeast gene enhances gene targeting when expressed in Arabidopsis thaliana. In this work we address the trans-species compatibility of Rad54 functions. We show that overexpression of yeast RAD54 in Arabidopsis enhances DNA damage resistance severalfold. Thus, the yeast gene is active in the Arabidopsis homologous-recombination repair system. Moreover, we have identified an A. thaliana ortholog of yeast RAD54, named AtRAD54. This gene, with close sequence similarity to RAD54, complements methylmethane sulfonate (MMS) sensitivity but not UV sensitivity or gene targeting defects of rad54Delta mutant yeast cells. Overexpression of AtRAD54 in Arabidopsis leads to enhanced resistance to DNA damage. This gene's assignment as a RAD54 ortholog is further supported by the interaction of AtRad54 with AtRad51 and the interactions between alien proteins (i.e., yeast Rad54 with AtRAD51 and yeast Rad51 with AtRad54) in a yeast two-hybrid experiment. These interactions hint at the molecular nature of this interkingdom complementation, although the stronger effect of the yeast Rad54 in plants than AtRad54 in yeast might be explained by an ability of the Rad54 protein to act alone, independently of its interaction with Rad51.

  11. Influence of ALA54THR polymorphism of fatty acid binding protein 2 on lifestyle modification response in obese subjects.

    PubMed

    de Luis, D A; Aller, R; Izaola, O; Sagrado, M Gonzalez; Conde, R

    2006-01-01

    It has been found that the expression of fatty acid binding protein 2 (FABP2) mRNA is under dietary control. A G-to-A transition at codon 54 of FABP2 results in an amino acid substitution (from Ala 54 to Thr 54). This polymorphism was associated with high insulin resistance and high fasting insulin concentrations. The aim of our study was to investigate the influence of Thr54 polymorphism in the FABP2 protein on the response to a lifestyle modification (Mediterranean hypocaloric diet and exercise) in obese patients. A population of 69 obese (body mass index > 30) nondiabetic outpatients was analyzed in a prospective way. Before and after 3 months of the lifestyle modification program, indirect calorimetry, tetrapolar electrical bioimpedance measurement, blood pressure recording, serial assessment of the nutritional intake (3 days of written food records), and biochemical analysis were performed. The lifestyle modification program consisted of a hypocaloric diet (1,520 kcal; 52% carbohydrates, 25% lipids, and 23% proteins). The exercise program consisted of aerobic exercise for at least three times/week (60 min each). Statistical analysis was performed for combined Ala54/Thr54 and Thr54/Thr54 as a mutant group and wild-type Ala54/Ala54 as second group. The mean age was 45.5 +/- 16.7 years, the mean body mass index was 34.1 +/- 5.1, and there were 14 males (20.3%) and 55 females (79.7%) with a weight loss of 3.17 +/- 3.5 kg (3.5%). Thirty-seven patients (53.6%) had the genotype Ala54/Ala54 (wild-type group) and 32 (46.4%) patients either the genotype Ala54/Thr54 (26 patients, 30.2%) or the genotype Thr54/Thr54 (6 patients, 16.2%). The percentage of responders (weight loss) was similar in both groups (89.2 vs. 90.6%). In the wild-type group, body mass index, weight, fat mass, low-density lipoprotein cholesterol level, and waist circumference decreased, whereas the VO2 (oxygen consumption) increased. In the mutant group, glucose, body mass index, weight, waist

  12. Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond–like features

    PubMed Central

    Konantz, Martina; Paillard, Catherine; Miao, Zhichao; Pichot, Angélique; Leduc, Magalie S.; Yang, Yaping; Bergstrom, Katie L.; Mahoney, Donald H.; Shardy, Deborah L.; Alsaleh, Ghada; Naegely, Lydie; Kolmer, Aline; Paul, Nicodème; Hanauer, Antoine; Rolli, Véronique; Müller, Joëlle S.; Alghisi, Elisa; Sauteur, Loïc; Macquin, Cécile; Morlon, Aurore; Sancho, Consuelo Sebastia; Amati-Bonneau, Patrizia; Procaccio, Vincent; Mosca-Boidron, Anne-Laure; Marle, Nathalie; Goetz, Jacky G.; Unal, Sule; Akarsu, Nurten A.; Radosavljevic, Mirjana; Chenard, Marie-Pierre; Rialland, Fanny; Grain, Audrey; Béné, Marie-Christine; Eveillard, Marion; Vincent, Marie; Guy, Julien; Faivre, Laurence; Thauvin-Robinet, Christel; Thevenon, Julien; Fleming, Mark D.; Bottollier-Lemallaz, Elodie; Westhof, Eric; Isidor, Bertrand

    2017-01-01

    Shwachman-Diamond syndrome (SDS) (OMIM #260400) is a rare inherited bone marrow failure syndrome (IBMFS) that is primarily characterized by neutropenia and exocrine pancreatic insufficiency. Seventy-five to ninety percent of patients have compound heterozygous loss-of-function mutations in the Shwachman-Bodian-Diamond syndrome (sbds) gene. Using trio whole-exome sequencing (WES) in an sbds-negative SDS family and candidate gene sequencing in additional SBDS-negative SDS cases or molecularly undiagnosed IBMFS cases, we identified 3 independent patients, each of whom carried a de novo missense variant in srp54 (encoding signal recognition particle 54 kDa). These 3 patients shared congenital neutropenia linked with various other SDS phenotypes. 3D protein modeling revealed that the 3 variants affect highly conserved amino acids within the GTPase domain of the protein that are critical for GTP and receptor binding. Indeed, we observed that the GTPase activity of the mutated proteins was impaired. The level of SRP54 mRNA in the bone marrow was 3.6-fold lower in patients with SRP54-mutations than in healthy controls. Profound reductions in neutrophil counts and chemotaxis as well as a diminished exocrine pancreas size in a SRP54-knockdown zebrafish model faithfully recapitulated the human phenotype. In conclusion, autosomal dominant mutations in SRP54, a key member of the cotranslation protein-targeting pathway, lead to syndromic neutropenia with a Shwachman-Diamond–like phenotype. PMID:28972538

  13. Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond-like features.

    PubMed

    Carapito, Raphael; Konantz, Martina; Paillard, Catherine; Miao, Zhichao; Pichot, Angélique; Leduc, Magalie S; Yang, Yaping; Bergstrom, Katie L; Mahoney, Donald H; Shardy, Deborah L; Alsaleh, Ghada; Naegely, Lydie; Kolmer, Aline; Paul, Nicodème; Hanauer, Antoine; Rolli, Véronique; Müller, Joëlle S; Alghisi, Elisa; Sauteur, Loïc; Macquin, Cécile; Morlon, Aurore; Sancho, Consuelo Sebastia; Amati-Bonneau, Patrizia; Procaccio, Vincent; Mosca-Boidron, Anne-Laure; Marle, Nathalie; Osmani, Naël; Lefebvre, Olivier; Goetz, Jacky G; Unal, Sule; Akarsu, Nurten A; Radosavljevic, Mirjana; Chenard, Marie-Pierre; Rialland, Fanny; Grain, Audrey; Béné, Marie-Christine; Eveillard, Marion; Vincent, Marie; Guy, Julien; Faivre, Laurence; Thauvin-Robinet, Christel; Thevenon, Julien; Myers, Kasiani; Fleming, Mark D; Shimamura, Akiko; Bottollier-Lemallaz, Elodie; Westhof, Eric; Lengerke, Claudia; Isidor, Bertrand; Bahram, Seiamak

    2017-11-01

    Shwachman-Diamond syndrome (SDS) (OMIM #260400) is a rare inherited bone marrow failure syndrome (IBMFS) that is primarily characterized by neutropenia and exocrine pancreatic insufficiency. Seventy-five to ninety percent of patients have compound heterozygous loss-of-function mutations in the Shwachman-Bodian-Diamond syndrome (sbds) gene. Using trio whole-exome sequencing (WES) in an sbds-negative SDS family and candidate gene sequencing in additional SBDS-negative SDS cases or molecularly undiagnosed IBMFS cases, we identified 3 independent patients, each of whom carried a de novo missense variant in srp54 (encoding signal recognition particle 54 kDa). These 3 patients shared congenital neutropenia linked with various other SDS phenotypes. 3D protein modeling revealed that the 3 variants affect highly conserved amino acids within the GTPase domain of the protein that are critical for GTP and receptor binding. Indeed, we observed that the GTPase activity of the mutated proteins was impaired. The level of SRP54 mRNA in the bone marrow was 3.6-fold lower in patients with SRP54-mutations than in healthy controls. Profound reductions in neutrophil counts and chemotaxis as well as a diminished exocrine pancreas size in a SRP54-knockdown zebrafish model faithfully recapitulated the human phenotype. In conclusion, autosomal dominant mutations in SRP54, a key member of the cotranslation protein-targeting pathway, lead to syndromic neutropenia with a Shwachman-Diamond-like phenotype.

  14. Inhibition of metastin (kisspeptin-54)-GPR54 signaling in the arcuate nucleus-median eminence region during lactation in rats.

    PubMed

    Yamada, S; Uenoyama, Y; Kinoshita, M; Iwata, K; Takase, K; Matsui, H; Adachi, S; Inoue, K; Maeda, K-I; Tsukamura, H

    2007-05-01

    Follicular development and ovulation are suppressed during lactation in various mammalian species, mainly due to the suppression of pulsatile GnRH/LH secretion. Metastin (kisspeptin-54), a KiSS-1 gene product, is an endogenous ligand for GPR54, a G-protein-coupled receptor, and suggested to play a critical role in regulating the gonadal axis. The present study therefore aims to determine whether metastin (kisspeptin-54)-GPR54 signaling in discrete brain areas is inhibited by the suckling stimulus that causes suppression of LH secretion in lactating rats. Quantitative RT-PCR revealed that the KiSS-1 mRNA level was significantly lower in the arcuate nucleus (ARC)-median eminence region in lactating ovariectomized (OVX) and estrogen-treated OVX rats than in nonlactating controls. KiSS-1 mRNA in the anteroventral periventricular nucleus was kept at a low level in both lactating and nonlactating rats despite estrogen treatment. GPR54 mRNA levels were significantly lower in lactating than nonlactating rats in the anteroventral periventricular nucleus, but the levels in lactating mothers of the preoptic area and ARC-median eminence were comparable with nonlactating controls. Although KiSS-1 mRNA-expressing cells or metastin (kisspeptin-54) immunoreactivities were densely located in the ARC of nonlactating controls, few were found in the ARC of lactating OVX animals. Various doses of metastin (kisspeptin-54) (0.02, 0.2, and 2 nmol) injected into the third ventricle caused a significant increase in LH secretion in both lactating and nonlactating OVX rats, suggesting that lactating rats are responsive to metastin (kisspeptin-54) stimulus. Thus, the present study demonstrated that KiSS-1 mRNA/metastin (kisspeptin-54) expression is inhibited in the ARC by the suckling stimulus, suggesting that the inhibition is most probably involved in suppressing LH secretion in lactating rats.

  15. 28 CFR 54.310 - Recruitment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Recruitment. 54.310 Section 54.310 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN... §§ 54.300 through 54.310 apply shall not recruit primarily or exclusively at educational institutions...

  16. 41 CFR 105-54.101 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Applicability. 105-54.101 Section 105-54.101 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.1-General Provisions § 105-54.101 Applicability. This part 105...

  17. p54nrb is a new regulator of progression of malignant melanoma.

    PubMed

    Schiffner, Susanne; Zimara, Nicole; Schmid, Rainer; Bosserhoff, Anja-Katrin

    2011-08-01

    Nuclear RNA-binding protein p54(nrb) and its murine homolog NonO are known to be involved in a variety of nuclear processes including transcription and RNA processing. Melanoma inhibitory activity (MIA) has been shown to play an essential role in the progression of malignant melanoma and to influence melanoma-associated molecules and pathways in the early tumor formation steps. Interestingly, recent studies suggest that MIA is a regulator of p54(nrb). Here, we show that p54(nrb) is strongly expressed and localized in the nucleus of both melanoma cell lines and melanoma tissue samples compared with normal human melanocytes or normal skin, respectively. Furthermore, all tested melanoma cell lines revealed strong p54(nrb) promoter activity. Treatment with MIA-specific small interfering RNAs showed an influence of MIA on p54(nrb) expression on both messenger RNA (mRNA) and protein level. Knockdown of p54(nrb) protein in melanoma cell lines led to reduced proliferation rates and to a strong decrease in their migratory potential. In addition, attachment to laminin and poly-l-lysine was significantly increased. We could identify Connexin-43 (Cx-43) as a downstream target molecule of p54(nrb) as knockdown of p54(nrb) resulted in enhanced Cx-43 mRNA and protein levels. As a confirmation of these findings, melanoma cell lines showed very low Cx-43 expression levels compared with melanocytes. Our results demonstrate that p54(nrb) is highly expressed in malignant melanoma and, as a MIA target molecule, it seems to be involved in the development and progression of malignant melanoma.

  18. 47 CFR 54.522 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false [Reserved] 54.522 Section 54.522 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Schools and Libraries § 54.522 [Reserved] ...

  19. 47 CFR 54.522 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false [Reserved] 54.522 Section 54.522 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Schools and Libraries § 54.522 [Reserved] ...

  20. 47 CFR 54.506 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false [Reserved] 54.506 Section 54.506 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Schools and Libraries § 54.506 [Reserved] ...

  1. 47 CFR 54.506 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false [Reserved] 54.506 Section 54.506 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Schools and Libraries § 54.506 [Reserved] ...

  2. 47 CFR 54.517 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false [Reserved] 54.517 Section 54.517 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Schools and Libraries § 54.517 [Reserved] ...

  3. 47 CFR 54.517 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false [Reserved] 54.517 Section 54.517 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Schools and Libraries § 54.517 [Reserved] ...

  4. 40 CFR 418.54 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 29 2014-07-01 2012-07-01 true [Reserved] 418.54 Section 418.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS FERTILIZER MANUFACTURING POINT SOURCE CATEGORY Nitric Acid Subcategory § 418.54 [Reserved] ...

  5. 40 CFR 418.54 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 30 2012-07-01 2012-07-01 false [Reserved] 418.54 Section 418.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS FERTILIZER MANUFACTURING POINT SOURCE CATEGORY Nitric Acid Subcategory § 418.54 [Reserved] ...

  6. 40 CFR 418.54 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 30 2013-07-01 2012-07-01 true [Reserved] 418.54 Section 418.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS FERTILIZER MANUFACTURING POINT SOURCE CATEGORY Nitric Acid Subcategory § 418.54 [Reserved] ...

  7. 40 CFR 418.54 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 29 2011-07-01 2009-07-01 true [Reserved] 418.54 Section 418.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS FERTILIZER MANUFACTURING POINT SOURCE CATEGORY Nitric Acid Subcategory § 418.54 [Reserved] ...

  8. 40 CFR 418.54 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true [Reserved] 418.54 Section 418.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS FERTILIZER MANUFACTURING POINT SOURCE CATEGORY Nitric Acid Subcategory § 418.54 [Reserved] ...

  9. 40 CFR 461.54 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 30 2011-07-01 2011-07-01 false [Reserved] 461.54 Section 461.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS BATTERY MANUFACTURING POINT SOURCE CATEGORY Lithium Subcategory § 461.54 [Reserved] ...

  10. 40 CFR 461.54 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 31 2012-07-01 2012-07-01 false [Reserved] 461.54 Section 461.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS (CONTINUED) BATTERY MANUFACTURING POINT SOURCE CATEGORY Lithium Subcategory § 461.54 [Reserved] ...

  11. 40 CFR 461.54 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false [Reserved] 461.54 Section 461.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS BATTERY MANUFACTURING POINT SOURCE CATEGORY Lithium Subcategory § 461.54 [Reserved] ...

  12. 47 CFR 54.649 - Certifications.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Certifications. 54.649 Section 54.649 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Health Care Providers Healthcare Connect Fund § 54.649...

  13. 47 CFR 54.649 - Certifications.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Certifications. 54.649 Section 54.649 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Health Care Providers Healthcare Connect Fund § 54.649...

  14. 40 CFR 461.54 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 31 2013-07-01 2013-07-01 false [Reserved] 461.54 Section 461.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS (CONTINUED) BATTERY MANUFACTURING POINT SOURCE CATEGORY Lithium Subcategory § 461.54 [Reserved] ...

  15. 40 CFR 461.54 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 30 2014-07-01 2014-07-01 false [Reserved] 461.54 Section 461.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS (CONTINUED) BATTERY MANUFACTURING POINT SOURCE CATEGORY Lithium Subcategory § 461.54 [Reserved] ...

  16. 47 CFR 54.516 - Auditing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Auditing. 54.516 Section 54.516 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Schools and Libraries § 54.516 Auditing. (a) Recordkeeping...

  17. 40 CFR 426.54 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 30 2011-07-01 2011-07-01 false [Reserved] 426.54 Section 426.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS GLASS MANUFACTURING POINT SOURCE CATEGORY Float Glass Manufacturing Subcategory § 426.54 [Reserved] ...

  18. 40 CFR 426.54 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false [Reserved] 426.54 Section 426.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS GLASS MANUFACTURING POINT SOURCE CATEGORY Float Glass Manufacturing Subcategory § 426.54 [Reserved] ...

  19. 28 CFR 54.510 - Recruitment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Recruitment. 54.510 Section 54.510 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN... in Employment in Education Programs or Activities Prohibited § 54.510 Recruitment. (a...

  20. 28 CFR 54.510 - Recruitment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Recruitment. 54.510 Section 54.510 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN... in Employment in Education Programs or Activities Prohibited § 54.510 Recruitment. (a...

  1. 7 CFR 54.3 - Authority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Authority. 54.3 Section 54.3 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections... PRODUCTS (GRADING, CERTIFICATION, AND STANDARDS) Regulations Administration § 54.3 Authority. The Chief is...

  2. 28 CFR 54.200 - Application.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Application. 54.200 Section 54.200 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Coverage § 54.200 Application...

  3. 40 CFR 415.54 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true [Reserved] 415.54 Section 415.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS INORGANIC CHEMICALS MANUFACTURING POINT SOURCE CATEGORY Calcium Oxide Production Subcategory § 415.54...

  4. 28 CFR 54.540 - Advertising.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Advertising. 54.540 Section 54.540... in Employment in Education Programs or Activities Prohibited § 54.540 Advertising. A recipient shall not in any advertising related to employment indicate preference, limitation, specification, or...

  5. 28 CFR 54.540 - Advertising.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Advertising. 54.540 Section 54.540... in Employment in Education Programs or Activities Prohibited § 54.540 Advertising. A recipient shall not in any advertising related to employment indicate preference, limitation, specification, or...

  6. 28 CFR 54.540 - Advertising.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Advertising. 54.540 Section 54.540... in Employment in Education Programs or Activities Prohibited § 54.540 Advertising. A recipient shall not in any advertising related to employment indicate preference, limitation, specification, or...

  7. 28 CFR 54.540 - Advertising.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Advertising. 54.540 Section 54.540... in Employment in Education Programs or Activities Prohibited § 54.540 Advertising. A recipient shall not in any advertising related to employment indicate preference, limitation, specification, or...

  8. 28 CFR 54.540 - Advertising.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Advertising. 54.540 Section 54.540... in Employment in Education Programs or Activities Prohibited § 54.540 Advertising. A recipient shall not in any advertising related to employment indicate preference, limitation, specification, or...

  9. 34 CFR 674.54 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false [Reserved] 674.54 Section 674.54 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION FEDERAL PERKINS LOAN PROGRAM Loan Cancellation § 674.54 [Reserved] ...

  10. 34 CFR 674.54 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false [Reserved] 674.54 Section 674.54 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION FEDERAL PERKINS LOAN PROGRAM Loan Cancellation § 674.54 [Reserved] ...

  11. 9 CFR 54.20 - Administration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Administration. 54.20 Section 54.20 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... Certification Program § 54.20 Administration. The Scrapie Flock Certification Program is a cooperative effort...

  12. 9 CFR 54.20 - Administration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Administration. 54.20 Section 54.20 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... Certification Program § 54.20 Administration. The Scrapie Flock Certification Program is a cooperative effort...

  13. 9 CFR 54.20 - Administration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Administration. 54.20 Section 54.20 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... Certification Program § 54.20 Administration. The Scrapie Flock Certification Program is a cooperative effort...

  14. 28 CFR 54.510 - Recruitment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Recruitment. 54.510 Section 54.510... in Employment in Education Programs or Activities Prohibited § 54.510 Recruitment. (a) Nondiscriminatory recruitment and hiring. A recipient shall not discriminate on the basis of sex in the recruitment...

  15. The Role of Bacterial Enhancer Binding Proteins as Specialized Activators of σ54-Dependent Transcription

    PubMed Central

    2012-01-01

    Summary: Bacterial enhancer binding proteins (bEBPs) are transcriptional activators that assemble as hexameric rings in their active forms and utilize ATP hydrolysis to remodel the conformation of RNA polymerase containing the alternative sigma factor σ54. We present a comprehensive and detailed summary of recent advances in our understanding of how these specialized molecular machines function. The review is structured by introducing each of the three domains in turn: the central catalytic domain, the N-terminal regulatory domain, and the C-terminal DNA binding domain. The role of the central catalytic domain is presented with particular reference to (i) oligomerization, (ii) ATP hydrolysis, and (iii) the key GAFTGA motif that contacts σ54 for remodeling. Each of these functions forms a potential target of the signal-sensing N-terminal regulatory domain, which can act either positively or negatively to control the activation of σ54-dependent transcription. Finally, we focus on the DNA binding function of the C-terminal domain and the enhancer sites to which it binds. Particular attention is paid to the importance of σ54 to the bacterial cell and its unique role in regulating transcription. PMID:22933558

  16. Expedition 54 Post Flight

    NASA Image and Video Library

    2018-06-13

    Expedition 54 NASA astronauts Joe Acaba, left, and Mark Vande Hei meet with NASA Administrator Jim Bridenstine during their Expedition 54 post flight visit, Wednesday, June 13, 2018 at NASA Headquarters, Washington. Photo Credit: (NASA/Bill Ingalls)

  17. Expedition 54 Post Flight

    NASA Image and Video Library

    2018-06-13

    NASA Administrator Jim Bridenstine, left, meets with Expedition 54 NASA astronauts Joe Acaba, center, and Mark Vande Hei during their Expedition 54 post flight, Wednesday, June 13, 2018 at NASA Headquarters, Washington. Photo Credit: (NASA/Bill Ingalls)

  18. Expedition 54 Post Flight

    NASA Image and Video Library

    2018-06-13

    NASA Administrator Jim Bridenstine, center, meets with Expedition 54 NASA astronauts Mark Vande Hei, left, and Joe Acaba during their Expedition 54 post flight, Wednesday, June 13, 2018 at NASA Headquarters, Washington. Photo Credit: (NASA/Bill Ingalls)

  19. Expedition 54 Post Flight

    NASA Image and Video Library

    2018-06-13

    NASA Administrator Jim Bridenstine, right, meets with Expedition 54 NASA astronauts Mark Vande Hei, left, and Joe Acaba during their Expedition 54 post flight, Wednesday, June 13, 2018 at NASA Headquarters, Washington. Photo Credit: (NASA/Bill Ingalls)

  20. 15 CFR 400.54 - Information.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 2 2014-01-01 2014-01-01 false Information. 400.54 Section 400.54..., Notice, Hearings and Information § 400.54 Information. (a) Request for information. The Executive Secretary, on behalf of the Board, may request submission of any information, including business proprietary...

  1. 15 CFR 400.54 - Information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 2 2013-01-01 2013-01-01 false Information. 400.54 Section 400.54..., Notice, Hearings and Information § 400.54 Information. (a) Request for information. The Executive Secretary, on behalf of the Board, may request submission of any information, including business proprietary...

  2. 7 CFR 1030.54 - Equivalent price.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Equivalent price. 1030.54 Section 1030.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Handling Class Prices § 1030.54 Equivalent price. See § 1000.54. ...

  3. 24 CFR 8.54 - Notice.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Notice. 8.54 Section 8.54 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development... URBAN DEVELOPMENT Enforcement § 8.54 Notice. (a) A recipient that employs fifteen or more persons shall...

  4. 7 CFR 932.54 - Transfers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., the transferring handler shall comply with all applicable regulations up to the time of such transfer... 7 Agriculture 8 2014-01-01 2014-01-01 false Transfers. 932.54 Section 932.54 Agriculture... Regulating Handling Regulations § 932.54 Transfers. Transfers within the area of olives from one handler to...

  5. 7 CFR 932.54 - Transfers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., the transferring handler shall comply with all applicable regulations up to the time of such transfer... 7 Agriculture 8 2010-01-01 2010-01-01 false Transfers. 932.54 Section 932.54 Agriculture... Regulating Handling Regulations § 932.54 Transfers. Transfers within the area of olives from one handler to...

  6. 7 CFR 932.54 - Transfers.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., the transferring handler shall comply with all applicable regulations up to the time of such transfer... 7 Agriculture 8 2012-01-01 2012-01-01 false Transfers. 932.54 Section 932.54 Agriculture... Regulating Handling Regulations § 932.54 Transfers. Transfers within the area of olives from one handler to...

  7. 7 CFR 932.54 - Transfers.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., the transferring handler shall comply with all applicable regulations up to the time of such transfer... 7 Agriculture 8 2013-01-01 2013-01-01 false Transfers. 932.54 Section 932.54 Agriculture... Regulating Handling Regulations § 932.54 Transfers. Transfers within the area of olives from one handler to...

  8. 7 CFR 932.54 - Transfers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., the transferring handler shall comply with all applicable regulations up to the time of such transfer... 7 Agriculture 8 2011-01-01 2011-01-01 false Transfers. 932.54 Section 932.54 Agriculture... Regulating Handling Regulations § 932.54 Transfers. Transfers within the area of olives from one handler to...

  9. 7 CFR 1005.54 - Equivalent price.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Equivalent price. 1005.54 Section 1005.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Handling Class Prices § 1005.54 Equivalent price. See § 1000.54. Uniform Prices ...

  10. 7 CFR 1006.54 - Equivalent price.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Equivalent price. 1006.54 Section 1006.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Handling Class Prices § 1006.54 Equivalent price. See § 1000.54. Uniform Prices ...

  11. 7 CFR 1131.54 - Equivalent price.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Equivalent price. 1131.54 Section 1131.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Handling Class Prices § 1131.54 Equivalent price. See § 1000.54. Uniform Prices ...

  12. 7 CFR 1007.54 - Equivalent price.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Equivalent price. 1007.54 Section 1007.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Handling Class Prices § 1007.54 Equivalent price. See § 1000.54. Uniform Prices ...

  13. 7 CFR 1033.54 - Equivalent price.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Equivalent price. 1033.54 Section 1033.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Handling Class Prices § 1033.54 Equivalent price. See § 1000.54. Producer Price Differential ...

  14. 7 CFR 1032.54 - Equivalent price.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Equivalent price. 1032.54 Section 1032.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Handling Class Prices § 1032.54 Equivalent price. See § 1000.54. Producer Price Differential ...

  15. 7 CFR 1126.54 - Equivalent price.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Equivalent price. 1126.54 Section 1126.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Handling Class Prices § 1126.54 Equivalent price. See § 1000.54. Producer Price Differential ...

  16. 9 CFR 54.21 - Participation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Participation. 54.21 Section 54.21 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF SCRAPIE Scrapie Flock Certification Program § 54.21 Participation. Any...

  17. 7 CFR 701.54 - Oysters.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Oysters. 701.54 Section 701.54 Agriculture Regulations... ADMINISTERED UNDER THIS PART § 701.54 Oysters. (a) Notwithstanding § 701.5(b), but otherwise subject to the... be made available under this section for the eligible cost of refurbishing public or private oyster...

  18. 40 CFR 96.54 - Compliance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Compliance. 96.54 Section 96.54... Tracking System § 96.54 Compliance. (a) NO X allowance transfer deadline. The NOX allowances are available to be deducted for compliance with a unit's NOX Budget emissions limitation for a control period in a...

  19. 40 CFR 96.54 - Compliance.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Compliance. 96.54 Section 96.54... Tracking System § 96.54 Compliance. (a) NO X allowance transfer deadline. The NOX allowances are available to be deducted for compliance with a unit's NOX Budget emissions limitation for a control period in a...

  20. 7 CFR 1124.54 - Equivalent price.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Equivalent price. 1124.54 Section 1124.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Regulating Handling Class Prices § 1124.54 Equivalent price. See § 1000.54. Producer Price Differential ...

  1. 21 CFR 54.3 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Scope. 54.3 Section 54.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL FINANCIAL DISCLOSURE BY CLINICAL INVESTIGATORS § 54.3 Scope. The requirements in this part apply to any applicant who submits a marketing...

  2. 10 CFR 1003.54 - Contents.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Contents. 1003.54 Section 1003.54 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICE OF HEARINGS AND APPEALS PROCEDURAL REGULATIONS Modification or Rescission § 1003.54 Contents. (a) The application shall contain a full and complete statement of all relevant facts pertaining to the circumstances, act...

  3. 10 CFR 1003.54 - Contents.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Contents. 1003.54 Section 1003.54 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICE OF HEARINGS AND APPEALS PROCEDURAL REGULATIONS Modification or Rescission § 1003.54 Contents. (a) The application shall contain a full and complete statement of all relevant facts pertaining to the circumstances, act...

  4. 10 CFR 1003.54 - Contents.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Contents. 1003.54 Section 1003.54 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICE OF HEARINGS AND APPEALS PROCEDURAL REGULATIONS Modification or Rescission § 1003.54 Contents. (a) The application shall contain a full and complete statement of all relevant facts pertaining to the circumstances, act...

  5. 10 CFR 1003.54 - Contents.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Contents. 1003.54 Section 1003.54 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICE OF HEARINGS AND APPEALS PROCEDURAL REGULATIONS Modification or Rescission § 1003.54 Contents. (a) The application shall contain a full and complete statement of all relevant facts pertaining to the circumstances, act...

  6. 10 CFR 1003.54 - Contents.

    Code of Federal Regulations, 2010 CFR

    2007-01-01

    ... 10 Energy 4 2007-01-01 2007-01-01 false Contents. 1003.54 Section 1003.54 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICE OF HEARINGS AND APPEALS PROCEDURAL REGULATIONS Modification or Rescission § 1003.54 Contents. (a) The application shall contain a full and complete statement of all relevant facts pertaining to the circumstances, act...

  7. 10 CFR 1003.54 - Contents.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Contents. 1003.54 Section 1003.54 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICE OF HEARINGS AND APPEALS PROCEDURAL REGULATIONS Modification or Rescission § 1003.54 Contents. (a) The application shall contain a full and complete statement of all relevant facts pertaining to the circumstances, act...

  8. Intestinal fatty acid binding protein Ala54Thr polymorphism is associated with peripheral atherosclerosis combined with type 2 diabetes mellitus.

    PubMed

    Khattab, Salma A; Abo-Elmatty, Dina M; Ghattas, Maivel H; Mesbah, Noha M; Mehanna, Eman T

    2017-09-01

    Intestinal fatty acid-binding protein 2 (FABP2) is expressed in enterocytes and binds saturated and unsaturated long-chain fatty acids. The FABP2 Ala54Thr polymorphism has been reported to effect lipid metabolism. The aim of the present study was to assess the relationship between this polymorphism and peripheral atherosclerosis combined with type 2 diabetes mellitus (T2DM) in an Egyptian population. The study was performed on 100 T2DM patients with peripheral atherosclerosis and 100 control subjects. The Ala54Thr polymorphism was analyzed by polymerase chain reaction-restriction fragment length polymorphism, whereas serum FABP2 levels were determined using ELISA. Fasting blood glucose, fasting serum insulin concentrations, HbA1c, lipid profile, body mass index (BMI) and systolic and diastolic blood pressure (SBP and DBP, respectively) were determined. There was a higher frequency of the Thr54 allele among the patient group (P = 0.002). In Ala54/Thr54 heterozygotes and carriers of the rare Thr54/Thr54 genotype, there were significant increases in BMI and FABP2. Those with the Thr54/Thr54 genotype had significantly decreased high-density lipoprotein cholesterol (HDL-C) concentrations; in addition, those with the Thr54/Thr54 genotype had significantly higher SBP and DBP than subjects with the Ala54/Ala54 and Ala54/Thr54 genotypes. There was a positive correlation between FABP2 levels and BMI, SBP and DBP, and a negative correlation with HDL-C. The Thr54 allele of the FABP2 Ala54Thr polymorphism was associated with an increased incidence of peripheral atherosclerosis combined with T2DM in the population studied. © 2016 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd.

  9. 29 CFR 6.54 - Hearing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Hearing. 6.54 Section 6.54 Labor Office of the Secretary of... Length Proceedings § 6.54 Hearing. (a) Except as provided in § 6.53(c) of this title, the hearing shall..., including the presentation of additional evidence, shall be considered at the hearing. There shall be a...

  10. 29 CFR 6.54 - Hearing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Hearing. 6.54 Section 6.54 Labor Office of the Secretary of... Length Proceedings § 6.54 Hearing. (a) Except as provided in § 6.53(c) of this title, the hearing shall..., including the presentation of additional evidence, shall be considered at the hearing. There shall be a...

  11. 29 CFR 6.54 - Hearing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Hearing. 6.54 Section 6.54 Labor Office of the Secretary of... Length Proceedings § 6.54 Hearing. (a) Except as provided in § 6.53(c) of this title, the hearing shall..., including the presentation of additional evidence, shall be considered at the hearing. There shall be a...

  12. 10 CFR 54.27 - Hearings.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Hearings. 54.27 Section 54.27 Energy NUCLEAR REGULATORY... Provisions § 54.27 Hearings. A notice of an opportunity for a hearing will be published in the Federal Register in accordance with 10 CFR 2.105. In the absence of a request for a hearing filed within 30 days by...

  13. 41 CFR 105-54.304 - Cost guidelines.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Cost guidelines. 105-54.304 Section 105-54.304 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.3-Advisory Committee Procedures § 105-54.304 Cost guidelines...

  14. 46 CFR 54.05-3 - Tests required.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Tests required. 54.05-3 Section 54.05-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Toughness Tests § 54.05-3 Tests required. (a) Where material or welding toughness tests are required by §§ 54.25-10, 54...

  15. 47 CFR 27.54 - Frequency stability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Frequency stability. 27.54 Section 27.54 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Technical Standards § 27.54 Frequency stability. The frequency stability shall be...

  16. 47 CFR 27.54 - Frequency stability.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false Frequency stability. 27.54 Section 27.54 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Technical Standards § 27.54 Frequency stability. The frequency stability shall be...

  17. 47 CFR 54.707 - Audit controls.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Audit controls. 54.707 Section 54.707 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Administration § 54.707 Audit controls. The Administrator shall have authority to audit...

  18. 47 CFR 54.707 - Audit controls.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Audit controls. 54.707 Section 54.707 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Administration § 54.707 Audit controls. The Administrator shall have authority to audit...

  19. 47 CFR 54.707 - Audit controls.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Audit controls. 54.707 Section 54.707 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Administration § 54.707 Audit controls. The Administrator shall have authority to audit...

  20. 47 CFR 54.707 - Audit controls.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Audit controls. 54.707 Section 54.707 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Administration § 54.707 Audit controls. The Administrator shall have authority to audit...

  1. 47 CFR 54.645 - Payment process.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Payment process. 54.645 Section 54.645 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Health Care Providers Healthcare Connect Fund § 54.645 Payment...

  2. 47 CFR 54.645 - Payment process.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Payment process. 54.645 Section 54.645 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Health Care Providers Healthcare Connect Fund § 54.645 Payment...

  3. 47 CFR 54.638 - Upfront payments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Upfront payments. 54.638 Section 54.638 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Health Care Providers Healthcare Connect Fund § 54.638 Upfront...

  4. 47 CFR 54.638 - Upfront payments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Upfront payments. 54.638 Section 54.638 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Health Care Providers Healthcare Connect Fund § 54.638 Upfront...

  5. 7 CFR 54.1033 - Confidential treatment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Confidential treatment. 54.1033 Section 54.1033 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... and Poultry Products § 54.1033 Confidential treatment. Every design review specialist providing...

  6. 10 CFR 54.7 - Written communications.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Written communications. 54.7 Section 54.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REQUIREMENTS FOR RENEWAL OF OPERATING LICENSES FOR NUCLEAR POWER PLANTS General Provisions § 54.7 Written communications. All applications, correspondence, reports, and other...

  7. 28 CFR 32.54 - Director determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Director determination. 32.54 Section 32.54 Judicial Administration DEPARTMENT OF JUSTICE PUBLIC SAFETY OFFICERS' DEATH, DISABILITY, AND EDUCATIONAL ASSISTANCE BENEFIT CLAIMS Director Appeals and Reviews § 32.54 Director determination. (a) Upon...

  8. 10 CFR 54.7 - Written communications.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Written communications. 54.7 Section 54.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REQUIREMENTS FOR RENEWAL OF OPERATING LICENSES FOR NUCLEAR POWER PLANTS General Provisions § 54.7 Written communications. All applications, correspondence, reports, and other...

  9. 28 CFR 32.54 - Director determination.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Director determination. 32.54 Section 32.54 Judicial Administration DEPARTMENT OF JUSTICE PUBLIC SAFETY OFFICERS' DEATH, DISABILITY, AND EDUCATIONAL ASSISTANCE BENEFIT CLAIMS Director Appeals and Reviews § 32.54 Director determination. (a) Upon...

  10. 28 CFR 54.410 - Comparable facilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Comparable facilities. 54.410 Section 54... in Education Programs or Activities Prohibited § 54.410 Comparable facilities. A recipient may provide separate toilet, locker room, and shower facilities on the basis of sex, but such facilities...

  11. 7 CFR 989.54 - Marketing policy.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Marketing policy. 989.54 Section 989.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CALIFORNIA Order Regulating Handling Marketing Policy § 989.54 Marketing policy. (a) Trade demand. On or...

  12. 7 CFR 989.54 - Marketing policy.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Marketing policy. 989.54 Section 989.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... CALIFORNIA Order Regulating Handling Marketing Policy § 989.54 Marketing policy. (a) Trade demand. On or...

  13. 7 CFR 989.54 - Marketing policy.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing policy. 989.54 Section 989.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... CALIFORNIA Order Regulating Handling Marketing Policy § 989.54 Marketing policy. (a) Trade demand. On or...

  14. 7 CFR 989.54 - Marketing policy.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Marketing policy. 989.54 Section 989.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CALIFORNIA Order Regulating Handling Marketing Policy § 989.54 Marketing policy. (a) Trade demand. On or...

  15. 7 CFR 989.54 - Marketing policy.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Marketing policy. 989.54 Section 989.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... CALIFORNIA Order Regulating Handling Marketing Policy § 989.54 Marketing policy. (a) Trade demand. On or...

  16. 40 CFR 205.54 - Test procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Test procedures. 205.54 Section 205.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.54 Test procedures. The procedures described...

  17. 47 CFR 54.508 - Technology plans.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Technology plans. 54.508 Section 54.508... SERVICE Universal Service Support for Schools and Libraries § 54.508 Technology plans. (a) Applicants must develop a technology plan when requesting discounts for internal connections and basic maintenance for...

  18. Unlike type 2 diabetes, type 1 does not interact with the codon 54 polymorphism of the fatty acid binding protein 2 gene.

    PubMed

    Georgopoulos, Angeliki; Aras, Omer; Noutsou, Marina; Tsai, Michael Y

    2002-08-01

    In type 2 diabetes, the threonine (Thr) for alanine (Ala) codon 54 polymorphism of the fatty acid binding protein 2 gene is associated with elevated fasting and postprandial triglycerides and dyslipidemia when compared with the wild type (Ala-54/Ala-54). To assess whether this is the case in patients with type 1 diabetes, who usually do not manifest the metabolic syndrome, we screened 181 patients with similar glycemic control as the type 2 patients. Thirty percent were heterozygous, and 9% were homozygous for the polymorphism. Mean (+/-SEM) fasting plasma triglyceride levels in patients with the wild type (n = 84), those heterozygous for Ala-54/Thr-54 (n = 44), and those homozygous for the Thr-54 (n = 13) were 1.0 +/- 0.07, 1.1 +/- 0.17, and 1.2 +/- 0.23 mmol/liter, respectively. In addition, there were no differences in total, low-density lipoprotein, high-density lipoprotein, and non-high density lipoprotein cholesterol among the three groups. After a fat load, the postprandial area under the curve of triglyceride in plasma, chylomicrons, and very low-density lipoprotein were similar between the wild type (n = 18) and the Thr-54 homozygotes (n = 12). In conclusion, in contrast to type 2, type 1 diabetes does not interact with the codon 54 polymorphism of the fatty acid binding protein 2 gene to cause hypertriglyceridemia/dyslipidemia. Insulin resistance could account possibly for this difference.

  19. 40 CFR 30.54 - Quality assurance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Quality assurance. 30.54 Section 30.54... NON-PROFIT ORGANIZATIONS Post-Award Requirements Reports and Records § 30.54 Quality assurance. If the... data generation, the grantee shall develop and implement quality assurance practices consisting of...

  20. 7 CFR 1700.54 - Electric Program.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 11 2012-01-01 2012-01-01 false Electric Program. 1700.54 Section 1700.54 Agriculture... GENERAL INFORMATION Loan and Grant Approval Authorities § 1700.54 Electric Program. (a) Administrator: The... Administrator, Electric Program, has the authority to approve the following loans, loan guarantees, and lien...

  1. 7 CFR 1700.54 - Electric Program.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 11 2014-01-01 2014-01-01 false Electric Program. 1700.54 Section 1700.54 Agriculture... GENERAL INFORMATION Loan and Grant Approval Authorities § 1700.54 Electric Program. (a) Administrator: The... Administrator, Electric Program, has the authority to approve the following loans, loan guarantees, and lien...

  2. 7 CFR 1700.54 - Electric Program.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 11 2013-01-01 2013-01-01 false Electric Program. 1700.54 Section 1700.54 Agriculture... GENERAL INFORMATION Loan and Grant Approval Authorities § 1700.54 Electric Program. (a) Administrator: The... Administrator, Electric Program, has the authority to approve the following loans, loan guarantees, and lien...

  3. 28 CFR 54.525 - Fringe benefits.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Fringe benefits. 54.525 Section 54.525... in Employment in Education Programs or Activities Prohibited § 54.525 Fringe benefits. (a) “Fringe benefits” defined. For purposes of these Title IX regulations, fringe benefits means: Any medical, hospital...

  4. 28 CFR 54.525 - Fringe benefits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Fringe benefits. 54.525 Section 54.525... in Employment in Education Programs or Activities Prohibited § 54.525 Fringe benefits. (a) “Fringe benefits” defined. For purposes of these Title IX regulations, fringe benefits means: Any medical, hospital...

  5. 28 CFR 54.525 - Fringe benefits.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Fringe benefits. 54.525 Section 54.525... in Employment in Education Programs or Activities Prohibited § 54.525 Fringe benefits. (a) “Fringe benefits” defined. For purposes of these Title IX regulations, fringe benefits means: Any medical, hospital...

  6. 28 CFR 54.525 - Fringe benefits.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Fringe benefits. 54.525 Section 54.525... in Employment in Education Programs or Activities Prohibited § 54.525 Fringe benefits. (a) “Fringe benefits” defined. For purposes of these Title IX regulations, fringe benefits means: Any medical, hospital...

  7. 10 CFR 54.15 - Specific exemptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Specific exemptions. 54.15 Section 54.15 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REQUIREMENTS FOR RENEWAL OF OPERATING LICENSES FOR NUCLEAR POWER PLANTS General Provisions § 54.15 Specific exemptions. Exemptions from the requirements of this part may be...

  8. Comparative analysis of activator-Eσ54 complexes formed with nucleotide-metal fluoride analogues

    PubMed Central

    Burrows, Patricia C.; Joly, Nicolas; Nixon, B. Tracy; Buck, Martin

    2009-01-01

    Bacterial RNA polymerase (RNAP) containing the major variant σ54 factor forms open promoter complexes in a reaction in which specialized activator proteins hydrolyse ATP. Here we probe binding interactions between σ54-RNAP (Eσ54) and the ATPases associated with various cellular activities (AAA+) domain of the Escherichia coli activator protein, PspF, using nucleotide-metal fluoride (BeF and AlF) analogues representing ground and transition states of ATP, which allow complexes (that are otherwise too transient with ATP) to be captured. We show that the organization and functionality of the ADP–BeF- and ADP–AlF-dependent complexes greatly overlap. Our data support an activation pathway in which the initial ATP-dependent binding of the activator to the Eσ54 closed complex results in the re-organization of Eσ54 with respect to the transcription start-site. However, the nucleotide-dependent binding interactions between the activator and the Eσ54 closed complex are in themselves insufficient for forming open promoter complexes when linear double-stranded DNA is present in the initial closed complex. PMID:19553192

  9. 46 CFR 503.54 - Original classification.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 9 2011-10-01 2011-10-01 false Original classification. 503.54 Section 503.54 Shipping... Program § 503.54 Original classification. (a) No Commission Member or employee has the authority to... require classification, or receives any foreign government information as defined in section 6.1(s) of...

  10. 46 CFR 503.54 - Original classification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Original classification. 503.54 Section 503.54 Shipping... Program § 503.54 Original classification. (a) No Commission Member or employee has the authority to... require classification, or receives any foreign government information as defined in section 1.1(d) of...

  11. 46 CFR 54.30-1 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Scope. 54.30-1 Section 54.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Mechanical Stress Relief § 54.30-1 Scope. (a) Certain pressure vessels may be mechanically stress relieved in accordance with the...

  12. 46 CFR 503.54 - Original classification.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 9 2012-10-01 2012-10-01 false Original classification. 503.54 Section 503.54 Shipping... Program § 503.54 Original classification. (a) No Commission Member or employee has the authority to... require classification, or receives any foreign government information as defined in section 6.1(s) of...

  13. 46 CFR 503.54 - Original classification.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 9 2013-10-01 2013-10-01 false Original classification. 503.54 Section 503.54 Shipping... Program § 503.54 Original classification. (a) No Commission Member or employee has the authority to... require classification, or receives any foreign government information as defined in section 6.1(s) of...

  14. 46 CFR 503.54 - Original classification.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 9 2014-10-01 2014-10-01 false Original classification. 503.54 Section 503.54 Shipping... Program § 503.54 Original classification. (a) No Commission Member or employee has the authority to... require classification, or receives any foreign government information as defined in section 6.1(s) of...

  15. 9 CFR 2.54 - Lost tags.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Lost tags. 2.54 Section 2.54 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Identification of Animals § 2.54 Lost tags. Each dealer or exhibitor shall be held...

  16. 7 CFR 906.54 - Effective time.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Effective time. 906.54 Section 906.54 Agriculture... RIO GRANDE VALLEY IN TEXAS Order Regulating Handling Miscellaneous Provisions § 906.54 Effective time. The provisions of this subpart, or any amendment thereto, shall become effective at such time as the...

  17. 7 CFR 906.54 - Effective time.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Effective time. 906.54 Section 906.54 Agriculture... RIO GRANDE VALLEY IN TEXAS Order Regulating Handling Miscellaneous Provisions § 906.54 Effective time. The provisions of this subpart, or any amendment thereto, shall become effective at such time as the...

  18. 7 CFR 906.54 - Effective time.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Effective time. 906.54 Section 906.54 Agriculture... RIO GRANDE VALLEY IN TEXAS Order Regulating Handling Miscellaneous Provisions § 906.54 Effective time. The provisions of this subpart, or any amendment thereto, shall become effective at such time as the...

  19. 7 CFR 906.54 - Effective time.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Effective time. 906.54 Section 906.54 Agriculture... RIO GRANDE VALLEY IN TEXAS Order Regulating Handling Miscellaneous Provisions § 906.54 Effective time. The provisions of this subpart, or any amendment thereto, shall become effective at such time as the...

  20. 7 CFR 906.54 - Effective time.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Effective time. 906.54 Section 906.54 Agriculture... RIO GRANDE VALLEY IN TEXAS Order Regulating Handling Miscellaneous Provisions § 906.54 Effective time. The provisions of this subpart, or any amendment thereto, shall become effective at such time as the...

  1. 46 CFR 54.30-1 - Scope.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Scope. 54.30-1 Section 54.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Mechanical Stress Relief § 54.30-1 Scope. (a) Certain pressure vessels may be mechanically stress relieved in accordance with the...

  2. 46 CFR 54.30-1 - Scope.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Scope. 54.30-1 Section 54.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Mechanical Stress Relief § 54.30-1 Scope. (a) Certain pressure vessels may be mechanically stress relieved in accordance with the...

  3. 46 CFR 54.30-1 - Scope.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Scope. 54.30-1 Section 54.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Mechanical Stress Relief § 54.30-1 Scope. (a) Certain pressure vessels may be mechanically stress relieved in accordance with the...

  4. 46 CFR 54.30-1 - Scope.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Scope. 54.30-1 Section 54.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Mechanical Stress Relief § 54.30-1 Scope. (a) Certain pressure vessels may be mechanically stress relieved in accordance with the...

  5. 11 CFR 111.54 - Bankruptcy claims.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 11 Federal Elections 1 2012-01-01 2012-01-01 false Bankruptcy claims. 111.54 Section 111.54 Federal Elections FEDERAL ELECTION COMMISSION GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Collection of Debts Arising From Enforcement and Administration of Campaign Finance Laws § 111.54 Bankruptcy...

  6. 11 CFR 111.54 - Bankruptcy claims.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 11 Federal Elections 1 2011-01-01 2011-01-01 false Bankruptcy claims. 111.54 Section 111.54 Federal Elections FEDERAL ELECTION COMMISSION GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Collection of Debts Arising From Enforcement and Administration of Campaign Finance Laws § 111.54 Bankruptcy...

  7. 11 CFR 111.54 - Bankruptcy claims.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 11 Federal Elections 1 2014-01-01 2014-01-01 false Bankruptcy claims. 111.54 Section 111.54 Federal Elections FEDERAL ELECTION COMMISSION GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Collection of Debts Arising From Enforcement and Administration of Campaign Finance Laws § 111.54 Bankruptcy...

  8. 49 CFR 195.54 - Accident reports.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Accident reports. 195.54 Section 195.54... PIPELINE Annual, Accident, and Safety-Related Condition Reporting § 195.54 Accident reports. (a) Each operator that experiences an accident that is required to be reported under § 195.50 shall as soon as...

  9. 9 CFR 2.54 - Lost tags.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Lost tags. 2.54 Section 2.54 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Identification of Animals § 2.54 Lost tags. Each dealer or exhibitor shall be held...

  10. 9 CFR 2.54 - Lost tags.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Lost tags. 2.54 Section 2.54 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Identification of Animals § 2.54 Lost tags. Each dealer or exhibitor shall be held...

  11. 9 CFR 2.54 - Lost tags.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Lost tags. 2.54 Section 2.54 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Identification of Animals § 2.54 Lost tags. Each dealer or exhibitor shall be held...

  12. 9 CFR 2.54 - Lost tags.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Lost tags. 2.54 Section 2.54 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Identification of Animals § 2.54 Lost tags. Each dealer or exhibitor shall be held...

  13. 7 CFR 900.54 - Docket number.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Docket number. 900.54 Section 900.54 Agriculture... Governing Proceedings on Petitions To Modify or To Be Exempted From Marketing Orders § 900.54 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the...

  14. 7 CFR 900.54 - Docket number.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Docket number. 900.54 Section 900.54 Agriculture... Governing Proceedings on Petitions To Modify or To Be Exempted From Marketing Orders § 900.54 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the...

  15. 7 CFR 900.54 - Docket number.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Docket number. 900.54 Section 900.54 Agriculture... Governing Proceedings on Petitions To Modify or To Be Exempted From Marketing Orders § 900.54 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the...

  16. 7 CFR 900.54 - Docket number.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Docket number. 900.54 Section 900.54 Agriculture... Governing Proceedings on Petitions To Modify or To Be Exempted From Marketing Orders § 900.54 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the...

  17. 7 CFR 900.54 - Docket number.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Docket number. 900.54 Section 900.54 Agriculture... Governing Proceedings on Petitions To Modify or To Be Exempted From Marketing Orders § 900.54 Docket number. Each proceeding, immediately following its institution, shall be assigned a docket number by the...

  18. 4 CFR 5.4 - Pay administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 4 Accounts 1 2010-01-01 2010-01-01 false Pay administration. 5.4 Section 5.4 Accounts GOVERNMENT ACCOUNTABILITY OFFICE PERSONNEL SYSTEM COMPENSATION § 5.4 Pay administration. The provisions of chapter 55 of title 5, U.S. Code and the Office of Personnel Management implementing regulations apply to Government...

  19. 47 CFR 54.508 - Technology plans.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Technology plans. 54.508 Section 54.508... SERVICE Universal Service Support for Schools and Libraries § 54.508 Technology plans. (a) Contents. The technology plans referred to in this subpart must include the following five elements: (1) A clear statement...

  20. 40 CFR 204.54 - Test procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Test procedures. 204.54 Section 204.54... STANDARDS FOR CONSTRUCTION EQUIPMENT Portable Air Compressors § 204.54 Test procedures. (a) General. This... which the test is conducted. (b) Test site description. The location for measuring noise employed during...

  1. 7 CFR 51.54 - Plant survey.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 2 2014-01-01 2014-01-01 false Plant survey. 51.54 Section 51.54 Agriculture... Contract Basis § 51.54 Plant survey. Prior to the inauguration of continuous Federal or Federal-State Inspection Service on a contract basis, the Administrator will make or cause to be made a survey and...

  2. 7 CFR 51.54 - Plant survey.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 2 2013-01-01 2013-01-01 false Plant survey. 51.54 Section 51.54 Agriculture... Contract Basis § 51.54 Plant survey. Prior to the inauguration of continuous Federal or Federal-State Inspection Service on a contract basis, the Administrator will make or cause to be made a survey and...

  3. 12 CFR 5.4 - Filing required.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Filing required. 5.4 Section 5.4 Banks and... CORPORATE ACTIVITIES Rules of General Applicability § 5.4 Filing required. (a) Filing. A depository... filings are available in the Manual and from each district office. (c) Other applications accepted. At the...

  4. 11 CFR 111.54 - Bankruptcy claims.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 11 Federal Elections 1 2013-01-01 2012-01-01 true Bankruptcy claims. 111.54 Section 111.54 Federal Elections FEDERAL ELECTION COMMISSION GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Collection of Debts Arising From Enforcement and Administration of Campaign Finance Laws § 111.54 Bankruptcy claims...

  5. 40 CFR 61.54 - Sludge sampling.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... maximum 24-hour period sludge incineration or drying rate shall be determined by use of a flow rate... 40 Protection of Environment 9 2012-07-01 2012-07-01 false Sludge sampling. 61.54 Section 61.54... EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standard for Mercury § 61.54 Sludge...

  6. 40 CFR 61.54 - Sludge sampling.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... maximum 24-hour period sludge incineration or drying rate shall be determined by use of a flow rate... 40 Protection of Environment 9 2013-07-01 2013-07-01 false Sludge sampling. 61.54 Section 61.54... EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standard for Mercury § 61.54 Sludge...

  7. 40 CFR 61.54 - Sludge sampling.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... maximum 24-hour period sludge incineration or drying rate shall be determined by use of a flow rate... 40 Protection of Environment 9 2014-07-01 2014-07-01 false Sludge sampling. 61.54 Section 61.54... EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standard for Mercury § 61.54 Sludge...

  8. 45 CFR 1801.54 - Annual report.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 4 2012-10-01 2012-10-01 false Annual report. 1801.54 Section 1801.54 Public Welfare Regulations Relating to Public Welfare (Continued) HARRY S. TRUMAN SCHOLARSHIP FOUNDATION HARRY S. TRUMAN SCHOLARSHIP PROGRAM Payment Conditions and Procedures § 1801.54 Annual report. (a) Scholars with remaining eligibility for scholarship...

  9. 40 CFR 205.54 - Test procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Test procedures. 205.54 Section 205.54... EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.54 Test procedures. The procedures described in this and subsequent sections will be the test program to determine the conformity of vehicles with...

  10. 40 CFR 205.54 - Test procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Test procedures. 205.54 Section 205.54... EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.54 Test procedures. The procedures described in this and subsequent sections will be the test program to determine the conformity of vehicles with...

  11. 7 CFR 983.54 - Commingling.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Commingling. 983.54 Section 983.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE PISTACHIOS GROWN IN CALIFORNIA...

  12. 7 CFR 51.54 - Plant survey.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 2 2012-01-01 2012-01-01 false Plant survey. 51.54 Section 51.54 Agriculture... Requirements for Plants Operating Under Continuous Inspection on A Contract Basis § 51.54 Plant survey. Prior..., the Administrator will make or cause to be made a survey and inspection where such service is to be...

  13. 7 CFR 51.54 - Plant survey.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Plant survey. 51.54 Section 51.54 Agriculture... Requirements for Plants Operating Under Continuous Inspection on A Contract Basis § 51.54 Plant survey. Prior..., the Administrator will make or cause to be made a survey and inspection where such service is to be...

  14. 7 CFR 51.54 - Plant survey.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false Plant survey. 51.54 Section 51.54 Agriculture... Requirements for Plants Operating Under Continuous Inspection on A Contract Basis § 51.54 Plant survey. Prior..., the Administrator will make or cause to be made a survey and inspection where such service is to be...

  15. 7 CFR 1000.54 - Equivalent price.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Equivalent price. 1000.54 Section 1000.54 Agriculture... Prices § 1000.54 Equivalent price. If for any reason a price or pricing constituent required for computing the prices described in § 1000.50 is not available, the market administrator shall use a price or...

  16. 14 CFR 1260.54 - Cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... cash and non-cash contributions shall be governed by § 1260.123, Cost Sharing or Matching. The... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Cost sharing. 1260.54 Section 1260.54... Special Conditions § 1260.54 Cost sharing. Cost Sharing October 2000 (a) NASA and the Recipient will share...

  17. 10 CFR § 1003.54 - Contents.

    Code of Federal Regulations, 2010 CFR

    2017-01-01

    ... 10 Energy 4 2017-01-01 2017-01-01 false Contents. § 1003.54 Section § 1003.54 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICE OF HEARINGS AND APPEALS PROCEDURAL REGULATIONS Modification or Rescission § 1003.54 Contents. (a) The application shall contain a full and complete statement of all relevant facts pertaining to the circumstances...

  18. 46 CFR 54.25-1 - Scope.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Scope. 54.25-1 Section 54.25-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Construction With Carbon, Alloy, and Heat Treated Steels § 54.25-1 Scope. The carbon, alloy, and heat treated steels used in construction of pressure vessels and parts shal...

  19. 46 CFR 54.25-1 - Scope.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Scope. 54.25-1 Section 54.25-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Construction With Carbon, Alloy, and Heat Treated Steels § 54.25-1 Scope. The carbon, alloy, and heat treated steels used in construction of pressure vessels and parts shal...

  20. 46 CFR 54.03-1 - Scope.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Scope. 54.03-1 Section 54.03-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Low Temperature Operation § 54.03-1 Scope. The pressure vessels for low temperature operation shall be as required by section VIII of the ASME Boiler and Pressure Vessel...

  1. 46 CFR 54.25-1 - Scope.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Scope. 54.25-1 Section 54.25-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Construction With Carbon, Alloy, and Heat Treated Steels § 54.25-1 Scope. The carbon, alloy, and heat treated steels used in construction of pressure vessels and parts shal...

  2. 46 CFR 54.25-1 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Scope. 54.25-1 Section 54.25-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Construction With Carbon, Alloy, and Heat Treated Steels § 54.25-1 Scope. The carbon, alloy, and heat treated steels used in construction of pressure vessels and parts shal...

  3. 46 CFR 54.03-1 - Scope.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Scope. 54.03-1 Section 54.03-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Low Temperature Operation § 54.03-1 Scope. The pressure vessels for low temperature operation shall be as required by section VIII of the ASME Boiler and Pressure Vessel...

  4. 46 CFR 54.03-1 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Scope. 54.03-1 Section 54.03-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Low Temperature Operation § 54.03-1 Scope. The pressure vessels for low temperature operation shall be as required by section VIII of the ASME Boiler and Pressure Vessel...

  5. 46 CFR 54.03-1 - Scope.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Scope. 54.03-1 Section 54.03-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Low Temperature Operation § 54.03-1 Scope. The pressure vessels for low temperature operation shall be as required by section VIII of the ASME Boiler and Pressure Vessel...

  6. 46 CFR 54.03-1 - Scope.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Scope. 54.03-1 Section 54.03-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Low Temperature Operation § 54.03-1 Scope. The pressure vessels for low temperature operation shall be as required by section VIII of the ASME Boiler and Pressure Vessel...

  7. 46 CFR 54.25-1 - Scope.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Scope. 54.25-1 Section 54.25-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Construction With Carbon, Alloy, and Heat Treated Steels § 54.25-1 Scope. The carbon, alloy, and heat treated steels used in construction of pressure vessels and parts shal...

  8. 28 CFR 54.220 - Admissions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... vocational education, professional education, graduate higher education, and public institutions of undergraduate higher education. (e) Public institutions of undergraduate higher education. §§ 54.300 through 54.310 do not apply to any public institution of undergraduate higher education that traditionally and...

  9. 28 CFR 54.220 - Admissions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... vocational education, professional education, graduate higher education, and public institutions of undergraduate higher education. (e) Public institutions of undergraduate higher education. §§ 54.300 through 54.310 do not apply to any public institution of undergraduate higher education that traditionally and...

  10. 28 CFR 54.220 - Admissions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... vocational education, professional education, graduate higher education, and public institutions of undergraduate higher education. (e) Public institutions of undergraduate higher education. §§ 54.300 through 54.310 do not apply to any public institution of undergraduate higher education that traditionally and...

  11. 28 CFR 54.220 - Admissions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... vocational education, professional education, graduate higher education, and public institutions of undergraduate higher education. (e) Public institutions of undergraduate higher education. §§ 54.300 through 54.310 do not apply to any public institution of undergraduate higher education that traditionally and...

  12. Phytoplasma Effector SAP54 Hijacks Plant Reproduction by Degrading MADS-box Proteins and Promotes Insect Colonization in a RAD23-Dependent Manner

    PubMed Central

    MacLean, Allyson M.; Orlovskis, Zigmunds; Kowitwanich, Krissana; Zdziarska, Anna M.; Angenent, Gerco C.; Immink, Richard G. H.; Hogenhout, Saskia A.

    2014-01-01

    Pathogens that rely upon multiple hosts to complete their life cycles often modify behavior and development of these hosts to coerce them into improving pathogen fitness. However, few studies describe mechanisms underlying host coercion. In this study, we elucidate the mechanism by which an insect-transmitted pathogen of plants alters floral development to convert flowers into vegetative tissues. We find that phytoplasma produce a novel effector protein (SAP54) that interacts with members of the MADS-domain transcription factor (MTF) family, including key regulators SEPALLATA3 and APETALA1, that occupy central positions in the regulation of floral development. SAP54 mediates degradation of MTFs by interacting with proteins of the RADIATION SENSITIVE23 (RAD23) family, eukaryotic proteins that shuttle substrates to the proteasome. Arabidopsis rad23 mutants do not show conversion of flowers into leaf-like tissues in the presence of SAP54 and during phytoplasma infection, emphasizing the importance of RAD23 to the activity of SAP54. Remarkably, plants with SAP54-induced leaf-like flowers are more attractive for colonization by phytoplasma leafhopper vectors and this colonization preference is dependent on RAD23. An effector that targets and suppresses flowering while simultaneously promoting insect herbivore colonization is unprecedented. Moreover, RAD23 proteins have, to our knowledge, no known roles in flower development, nor plant defence mechanisms against insects. Thus SAP54 generates a short circuit between two key pathways of the host to alter development, resulting in sterile plants, and promotes attractiveness of these plants to leafhopper vectors helping the obligate phytoplasmas reproduce and propagate (zombie plants). PMID:24714165

  13. Inhibition of Human Cytomegalovirus DNA Polymerase by C-Terminal Peptides from the UL54 Subunit

    PubMed Central

    Loregian, Arianna; Rigatti, Roberto; Murphy, Mary; Schievano, Elisabetta; Palu, Giorgio; Marsden, Howard S.

    2003-01-01

    In common with other herpesviruses, the human cytomegalovirus (HCMV) DNA polymerase contains a catalytic subunit (Pol or UL54) and an accessory protein (UL44) that is thought to increase the processivity of the enzyme. The observation that antisense inhibition of UL44 synthesis in HCMV-infected cells strongly inhibits viral DNA replication, together with the structural similarity predicted for the herpesvirus processivity subunits, highlights the importance of the accessory protein for virus growth and raises the possibility that the UL54/UL44 interaction might be a valid target for antiviral drugs. To investigate this possibility, overlapping peptides spanning residues 1161 to 1242 of UL54 were synthesized and tested for inhibition of the interaction between purified UL54 and UL44 proteins. A peptide, LPRRLHLEPAFLPYSVKAHECC, corresponding to residues 1221 to 1242 at the very C terminus of UL54, disrupted both the physical interaction between the two proteins and specifically inhibited the stimulation of UL54 by UL44. A mutant peptide lacking the two carboxy-terminal cysteines was markedly less inhibitory, suggesting a role for these residues in the UL54/UL44 interaction. Circular dichroism spectroscopy indicated that the UL54 C-terminal peptide can adopt a partially α-helical structure. Taken together, these results indicate that the two subunits of HCMV DNA polymerase most likely interact in a way which is analogous to that of the two subunits of herpes simplex virus DNA polymerase, even though there is no sequence homology in the binding site, and suggest that the UL54 peptide, or derivatives thereof, could form the basis for developing a new class of anti-HCMV inhibitors that act by disrupting the UL54/UL44 interaction. PMID:12857903

  14. 46 CFR 502.54 - Contents of rules.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Contents of rules. 502.54 Section 502.54 Shipping FEDERAL MARITIME COMMISSION GENERAL AND ADMINISTRATIVE PROVISIONS RULES OF PRACTICE AND PROCEDURE Rulemaking § 502.54 Contents of rules. The Commission will incorporate in any rules adopted a concise general statement of their basis and purpose. [Rule 54....

  15. The HLA-B*54:35 and -B*54:38 identified in volunteer donors for hematopoietic stem cell transplant.

    PubMed

    Baek, I-C; Choi, E-J; Shin, D-H; Kim, H-J; Kim, T-G

    2018-06-19

    HLA-B*54:35 and -B*54:38 differ from HLA-B*54:01:01 in codons in exons 2 and 3 This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  16. 28 CFR 54.500 - Employment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Employment. 54.500 Section 54.500 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN... employment on the basis of attendance at any educational institution or entity that admits as students only...

  17. 50 CFR 37.54 - Disclosure.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Disclosure. 37.54 Section 37.54 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) THE NATIONAL WILDLIFE REFUGE SYSTEM GEOLOGICAL AND GEOPHYSICAL EXPLORATION OF THE COASTAL PLAIN, ARCTIC...

  18. 50 CFR 37.54 - Disclosure.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 8 2011-10-01 2011-10-01 false Disclosure. 37.54 Section 37.54 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) THE NATIONAL WILDLIFE REFUGE SYSTEM GEOLOGICAL AND GEOPHYSICAL EXPLORATION OF THE COASTAL PLAIN, ARCTIC...

  19. High-resolution study of Gamow-Teller transitions via the 54Fe(3He,t)54Co reaction

    NASA Astrophysics Data System (ADS)

    Adachi, T.; Fujita, Y.; Bacher, A. D.; Berg, G. P. A.; Black, T.; de Frenne, D.; Foster, C. C.; Fujita, H.; Fujita, K.; Hatanaka, K.; Honma, M.; Jacobs, E.; Jänecke, J.; Kanzaki, K.; Katori, K.; Nakanishi, K.; Negret, A.; Otsuka, T.; Popescu, L.; Roberts, D. A.; Sakemi, Y.; Shimbara, Y.; Shimizu, Y.; Stephenson, E. J.; Tameshige, Y.; Tamii, A.; Uchida, M.; Ueno, H.; Yamanaka, T.; Yosoi, M.; Zell, K. O.

    2012-02-01

    The Gamow-Teller transition strengths, B(GT), in pf-shell nuclei are of interest in nuclear physics as well as in nuclear astrophysics. A high-resolution (3He,t) charge-exchange (CE) reaction was performed on the Tz=+1 nucleus 54Fe at 0∘ and at an intermediate incident energy of 140 MeV/nucleon for the study of precise GT transition strengths to the final Tz=0 nucleus 54Co. By applying dispersion matching techniques for a high-quality 3He beam at RCNP, an energy resolution of 21 keV and an angular resolution of 5 mr were realized. The bumplike structure of the GT resonance observed in low-resolution CE reactions at around the excitation energy (Ex) of 10 MeV was resolved in individual L = 0, GT states. Excitation strengths were obtained for these GT states. If the R2 value that is defined by the ratio between GT and Fermi unit cross sections is known, the B(GT) values can be determined from the excitation strengths. For the derivation of the R2 value, the “merged analysis” combining the GT strength distribution from the 54Fe(3He,t)54Co study and the half-life from a 54Ni β decay was used, where T=1 isospin symmetry for A=54 isobars was assumed. The GT strengths were compared with a shell-model calculation using the GXPF1 interaction. The final GT states can have the isospin values T = 0, 1, and 2. The isospin T of each GT state observed in the 8.3≤Ex≤12.0 MeV region of the 54Fe(3He,t)54Co spectrum was identified by comparing the excitation strength with that of corresponding M1 state observed in a 54Fe(p,p')54Fe experiment. The B(GT) values of the states identified to have T=2, in particular, are of importance for the calculation of the electron capture rates at the core-collapse stage of presupernovae. The B(GT) strengths were further compared with B(M1) strengths measured in the 54Fe(e,e')54Fe reaction. In the M1 excitation using an electromagnetic probe, isoscalar (IS) and isovector (IV) orbital type operators are active in addition to the IV spin

  20. Is His54 a gating residue for the ferritin ferroxidase site?

    PubMed

    Bernacchioni, Caterina; Ciambellotti, Silvia; Theil, Elizabeth C; Turano, Paola

    2015-09-01

    Ferritin is a ubiquitous iron concentrating nanocage protein that functions through the enzymatic oxidation of ferrous iron and the reversible synthesis of a caged ferric-oxo biomineral. Among vertebrate ferritins, the bullfrog M homopolymer ferritin is a frequent model for analyzing the role of specific amino acids in the enzymatic reaction and translocation of iron species within the protein cage. X-ray crystal structures of ferritin in the presence of metal ions have revealed His54 binding to iron(II) and other divalent cations, with its imidazole ring proposed as "gate" that influences iron movement to/from the active site. To investigate its role, His54 was mutated to Ala. The H54A ferritin variant was expressed and its reactivity studied via UV-vis stopped-flow kinetics. The H54A variant exhibited a 20% increase in the initial reaction rate of formation of ferric products with 2 or 4 Fe²⁺/subunit and higher than 200% with 20 Fe²⁺/subunit. The possible meaning of the increased efficiency of the ferritin reaction induced by this mutation is proposed taking advantage of the comparative sequence analysis of other ferritins. The data here reported are consistent with a role for His54 as a metal ion trap that maintains the correct levels of access of iron to the active site. This article is part of a Special Issue entitled: Cofactor-dependent proteins: evolution, chemical diversity and bio-applications. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. 41 CFR 105-54.200 - Scope of subpart.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Scope of subpart. 105-54.200 Section 105-54.200 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.2-Establishment of Advisory Committees § 105-54.200 Scope of...

  2. 41 CFR 105-54.300 - Scope of subpart.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Scope of subpart. 105-54.300 Section 105-54.300 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.3-Advisory Committee Procedures § 105-54.300 Scope of subpart...

  3. 41 CFR 105-54.200 - Scope of subpart.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Scope of subpart. 105-54.200 Section 105-54.200 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.2-Establishment of Advisory Committees § 105-54.200 Scope of...

  4. 41 CFR 105-54.300 - Scope of subpart.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Scope of subpart. 105-54.300 Section 105-54.300 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.3-Advisory Committee Procedures § 105-54.300 Scope of subpart...

  5. 41 CFR 105-54.200 - Scope of subpart.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Scope of subpart. 105-54.200 Section 105-54.200 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.2-Establishment of Advisory Committees § 105-54.200 Scope of...

  6. 41 CFR 105-54.300 - Scope of subpart.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Scope of subpart. 105-54.300 Section 105-54.300 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.3-Advisory Committee Procedures § 105-54.300 Scope of subpart...

  7. 41 CFR 105-54.200 - Scope of subpart.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Scope of subpart. 105-54.200 Section 105-54.200 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.2-Establishment of Advisory Committees § 105-54.200 Scope of...

  8. 41 CFR 105-54.200 - Scope of subpart.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Scope of subpart. 105-54.200 Section 105-54.200 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.2-Establishment of Advisory Committees § 105-54.200 Scope of...

  9. 41 CFR 105-54.300 - Scope of subpart.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Scope of subpart. 105-54.300 Section 105-54.300 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.3-Advisory Committee Procedures § 105-54.300 Scope of subpart...

  10. 41 CFR 105-54.300 - Scope of subpart.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Scope of subpart. 105-54.300 Section 105-54.300 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.3-Advisory Committee Procedures § 105-54.300 Scope of subpart...

  11. 28 CFR 54.220 - Admissions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN...) Admissions to educational institutions prior to June 24, 1973, are not covered by these Title IX regulations... §§ 54.300 through 54.310, each administratively separate unit shall be deemed to be an educational...

  12. 28 CFR 54.310 - Recruitment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex... recipient to which §§ 54.300 through 54.310 apply shall not discriminate on the basis of sex in the...

  13. 45 CFR 1170.54 - Notice.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Notice. 1170.54 Section 1170.54 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES NATIONAL ENDOWMENT FOR THE HUMANITIES NONDISCRIMINATION ON THE BASIS OF HANDICAP IN FEDERALLY ASSISTED PROGRAMS OR...

  14. 45 CFR 1170.54 - Notice.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Notice. 1170.54 Section 1170.54 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES NATIONAL ENDOWMENT FOR THE HUMANITIES NONDISCRIMINATION ON THE BASIS OF HANDICAP IN FEDERALLY ASSISTED PROGRAMS OR...

  15. 41 CFR 105-54.400 - Scope of subpart.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Scope of subpart. 105-54.400 Section 105-54.400 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.4-Reports § 105-54.400 Scope of subpart. This subpart sets...

  16. 41 CFR 105-54.400 - Scope of subpart.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Scope of subpart. 105-54.400 Section 105-54.400 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.4-Reports § 105-54.400 Scope of subpart. This subpart sets...

  17. 41 CFR 105-54.400 - Scope of subpart.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Scope of subpart. 105-54.400 Section 105-54.400 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.4-Reports § 105-54.400 Scope of subpart. This subpart sets...

  18. 41 CFR 105-54.400 - Scope of subpart.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Scope of subpart. 105-54.400 Section 105-54.400 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.4-Reports § 105-54.400 Scope of subpart. This subpart sets...

  19. 41 CFR 105-54.400 - Scope of subpart.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Scope of subpart. 105-54.400 Section 105-54.400 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.4-Reports § 105-54.400 Scope of subpart. This subpart sets...

  20. Expedition 54 Press Conference

    NASA Image and Video Library

    2017-12-16

    Expedition 54 backup crew member Sergey Prokopev is seen in quarantine, behind glass, during a press conference, Saturday, Dec. 16, 2017 at the Cosmonaut Hotel in Baikonur, Kazakhstan. Expedition 54 prime crew members Soyuz Commander Anton Shkaplerov of Roscosmos, flight engineer Scott Tingle of NASA, and flight engineer Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) are scheduled to launch to the International Space Station aboard the Soyuz spacecraft from the Baikonur Cosmodrome on December 17. Photo Credit: (NASA/Joel Kowsky)

  1. Expedition 54 Landing Preparations

    NASA Image and Video Library

    2018-02-26

    NASA, Roscosmos, and Russian Search and Rescue teams arrive at the Karagada airport to deploy to Zhezkazgan, Kazakhstan to pre-stage for the Soyuz MS-06 landing with Expedition 54 crew members Joe Acaba and Mark Vande Hei of NASA and cosmonaut Alexander Misurkin, Monday, Feb. 26, 2018. Acaba, Vande Hei, and Misurkin are returning after 168 days in space where they served as members of the Expedition 53 and 54 crews onboard the International Space Station. Photo Credit: (NASA/Bill Ingalls)

  2. Expedition 54 Landing Preparations

    NASA Image and Video Library

    2018-02-26

    NASA, Roscosmos, and Russian Search and Rescue teams arrive in Zhezkazgan, Kazakhstan to prepare for the Soyuz MS-06 landing with Expedition 54 crew members Joe Acaba and Mark Vande Hei of NASA and cosmonaut Alexander Misurkin near the town of Zhezkazgan, Kazakhstan on Monday, Feb. 26, 2018. Acaba, Vande Hei, and Misurkin are returning after 168 days in space where they served as members of the Expedition 53 and 54 crews onboard the International Space Station. Photo Credit: (NASA/Bill Ingalls)

  3. 9 CFR 54.1 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... project. A pilot project authorized by the Administrator in writing, designed to test or improve program... CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF SCRAPIE § 54.1 Definitions. Accredited... by the Administrator in accordance with § 54.11 to conduct one or more scrapie tests, or genotype...

  4. 9 CFR 54.1 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... project. A pilot project authorized by the Administrator in writing, designed to test or improve program... CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF SCRAPIE § 54.1 Definitions. Accredited... by the Administrator in accordance with § 54.11 to conduct one or more scrapie tests, or genotype...

  5. 9 CFR 54.1 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... project. A pilot project authorized by the Administrator in writing, designed to test or improve program... CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF SCRAPIE § 54.1 Definitions. Accredited... by the Administrator in accordance with § 54.11 to conduct one or more scrapie tests, or genotype...

  6. 9 CFR 54.1 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... project. A pilot project authorized by the Administrator in writing, designed to test or improve program... CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF SCRAPIE § 54.1 Definitions. Accredited... by the Administrator in accordance with § 54.11 to conduct one or more scrapie tests, or genotype...

  7. 9 CFR 54.1 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... project. A pilot project authorized by the Administrator in writing, designed to test or improve program... CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF SCRAPIE § 54.1 Definitions. Accredited... by the Administrator in accordance with § 54.11 to conduct one or more scrapie tests, or genotype...

  8. 40 CFR 97.54 - Compliance.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Compliance. 97.54 Section 97.54... Compliance. (a) NOX allowance transfer deadline. The NOX allowances are available to be deducted for compliance with a unit's NOX Budget emissions limitation for a control period in a given year only if the NOX...

  9. 40 CFR 97.54 - Compliance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Compliance. 97.54 Section 97.54... Compliance. (a) NOX allowance transfer deadline. The NOX allowances are available to be deducted for compliance with a unit's NOX Budget emissions limitation for a control period in a given year only if the NOX...

  10. 47 CFR 54.502 - Supported telecommunications services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Supported telecommunications services. 54.502 Section 54.502 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Schools and Libraries § 54.502 Supported...

  11. 17 CFR 201.54 - Settlement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Settlement. 201.54 Section 201... Regulations Pertaining to the Equal Access to Justice Act § 201.54 Settlement. The applicant and counsel for the Office or Division of the Commission may agree on a proposed settlement of the award before final...

  12. 21 CFR 54.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Definitions. 54.2 Section 54.2 Food and Drugs FOOD... outcome of clinical studies means compensation that could be higher for a favorable outcome than for an unfavorable outcome, such as compensation that is explicitly greater for a favorable result or compensation to...

  13. 21 CFR 54.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Definitions. 54.2 Section 54.2 Food and Drugs FOOD... outcome of clinical studies means compensation that could be higher for a favorable outcome than for an unfavorable outcome, such as compensation that is explicitly greater for a favorable result or compensation to...

  14. 21 CFR 54.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Definitions. 54.2 Section 54.2 Food and Drugs FOOD... outcome of clinical studies means compensation that could be higher for a favorable outcome than for an unfavorable outcome, such as compensation that is explicitly greater for a favorable result or compensation to...

  15. 21 CFR 54.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Definitions. 54.2 Section 54.2 Food and Drugs FOOD... outcome of clinical studies means compensation that could be higher for a favorable outcome than for an unfavorable outcome, such as compensation that is explicitly greater for a favorable result or compensation to...

  16. 21 CFR 54.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Definitions. 54.2 Section 54.2 Food and Drugs FOOD... outcome of clinical studies means compensation that could be higher for a favorable outcome than for an unfavorable outcome, such as compensation that is explicitly greater for a favorable result or compensation to...

  17. 22 CFR 40.54-40.59 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false [Reserved] 40.54-40.59 Section 40.54-40.59 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH NONIMMIGRANTS AND IMMIGRANTS... Immigrants §§ 40.54-40.59 [Reserved] ...

  18. 47 CFR 54.634 - Eligible services.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... SERVICE Universal Service Support for Health Care Providers Healthcare Connect Fund § 54.634 Eligible... through 54.680, eligible health care providers may request support from the Healthcare Connect Fund for...

  19. 47 CFR 54.634 - Eligible services.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SERVICE Universal Service Support for Health Care Providers Healthcare Connect Fund § 54.634 Eligible... through 54.680, eligible health care providers may request support from the Healthcare Connect Fund for...

  20. 47 CFR 54.603 - Competitive bid requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Competitive bid requirements. 54.603 Section 54...) UNIVERSAL SERVICE Universal Service Support for Health Care Providers § 54.603 Competitive bid requirements. (a) Competitive bidding requirement. To select the telecommunications carriers that will provide...

  1. 47 CFR 54.648 - Audits and recordkeeping.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Audits and recordkeeping. 54.648 Section 54.648 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Health Care Providers Healthcare Connect Fund § 54.648 Audits and...

  2. 47 CFR 54.648 - Audits and recordkeeping.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Audits and recordkeeping. 54.648 Section 54.648 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Health Care Providers Healthcare Connect Fund § 54.648 Audits and...

  3. 7 CFR 54.1005 - Basis of service.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Basis of service. 54.1005 Section 54.1005 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... and Poultry Products § 54.1005 Basis of service. (a) Certification of Sanitary Design and Fabrication...

  4. 7 CFR 54.1005 - Basis of service.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Basis of service. 54.1005 Section 54.1005 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... and Poultry Products § 54.1005 Basis of service. (a) Certification of Sanitary Design and Fabrication...

  5. 28 CFR 115.54 - Third-party reporting.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Third-party reporting. 115.54 Section 115.54 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Reporting § 115.54 Third-party reporting. The agency shall...

  6. 28 CFR 115.54 - Third-party reporting.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Third-party reporting. 115.54 Section 115.54 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Reporting § 115.54 Third-party reporting. The agency shall...

  7. 28 CFR 115.54 - Third-party reporting.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Third-party reporting. 115.54 Section 115.54 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Reporting § 115.54 Third-party reporting. The agency shall...

  8. 18 CFR 701.54 - Interagency Liaison Committee.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Interagency Liaison Committee. 701.54 Section 701.54 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Headquarters Organization § 701.54 Interagency Liaison Committee. There is established within the...

  9. 18 CFR 701.54 - Interagency Liaison Committee.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Interagency Liaison Committee. 701.54 Section 701.54 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Headquarters Organization § 701.54 Interagency Liaison Committee. There is established within the...

  10. 18 CFR 701.54 - Interagency Liaison Committee.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Interagency Liaison Committee. 701.54 Section 701.54 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Headquarters Organization § 701.54 Interagency Liaison Committee. There is established within the...

  11. 18 CFR 701.54 - Interagency Liaison Committee.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Interagency Liaison Committee. 701.54 Section 701.54 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Headquarters Organization § 701.54 Interagency Liaison Committee. There is established within the...

  12. 18 CFR 701.54 - Interagency Liaison Committee.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Interagency Liaison Committee. 701.54 Section 701.54 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Headquarters Organization § 701.54 Interagency Liaison Committee. There is established within the...

  13. 47 CFR 54.708 - De minimis exemption.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false De minimis exemption. 54.708 Section 54.708... SERVICE Administration § 54.708 De minimis exemption. If a contributor's contribution to universal service... those whose contributions would be de minimis, must file the Telecommunications Reporting Worksheet. If...

  14. 47 CFR 54.708 - De minimis exemption.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false De minimis exemption. 54.708 Section 54.708... SERVICE Administration § 54.708 De minimis exemption. If a contributor's contribution to universal service... those whose contributions would be de minimis, must file the Telecommunications Reporting Worksheet. If...

  15. Expedition 54 plaque hanging ceremony

    NASA Image and Video Library

    2018-04-26

    NASA astronauts Joe Acaba and Mark Vande Hei Acaba visited Marshall April 11 for their honorary Expedition 54 plaque hanging ceremony and to provide valuable feedback of their on-orbit science investigations with the Payload Operations and Integration Center team. Chris Buckley is awarded privilege of hanging Mission 54 placque, shown here with Astronaut Mark Vande Hei (L) and Astronaut Joe Acaba

  16. 7 CFR 1779.54-1779.58 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false [Reserved] 1779.54-1779.58 Section 1779.54-1779.58 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS §§ 1779.54-1779.58 [Reserved] ...

  17. 46 CFR 54.25-5 - Corrosion allowance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Corrosion allowance. 54.25-5 Section 54.25-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Construction With Carbon, Alloy, and Heat Treated Steels § 54.25-5 Corrosion allowance. The corrosion allowance...

  18. 46 CFR 54.25-5 - Corrosion allowance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Corrosion allowance. 54.25-5 Section 54.25-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Construction With Carbon, Alloy, and Heat Treated Steels § 54.25-5 Corrosion allowance. The corrosion allowance...

  19. 46 CFR 54.25-5 - Corrosion allowance.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Corrosion allowance. 54.25-5 Section 54.25-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Construction With Carbon, Alloy, and Heat Treated Steels § 54.25-5 Corrosion allowance. The corrosion allowance...

  20. 46 CFR 54.25-5 - Corrosion allowance.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Corrosion allowance. 54.25-5 Section 54.25-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Construction With Carbon, Alloy, and Heat Treated Steels § 54.25-5 Corrosion allowance. The corrosion allowance...

  1. 46 CFR 54.25-5 - Corrosion allowance.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Corrosion allowance. 54.25-5 Section 54.25-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Construction With Carbon, Alloy, and Heat Treated Steels § 54.25-5 Corrosion allowance. The corrosion allowance...

  2. 45 CFR 2400.54 - Use of stipend.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 4 2013-10-01 2013-10-01 false Use of stipend. 2400.54 Section 2400.54 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Fellowship Stipend § 2400.54 Use of stipend. Stipends shall be used only to...

  3. 45 CFR 2400.54 - Use of stipend.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false Use of stipend. 2400.54 Section 2400.54 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Fellowship Stipend § 2400.54 Use of stipend. Stipends shall be used only to...

  4. 45 CFR 2400.54 - Use of stipend.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 4 2012-10-01 2012-10-01 false Use of stipend. 2400.54 Section 2400.54 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Fellowship Stipend § 2400.54 Use of stipend. Stipends shall be used only to...

  5. 45 CFR 2400.54 - Use of stipend.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Use of stipend. 2400.54 Section 2400.54 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Fellowship Stipend § 2400.54 Use of stipend. Stipends shall be used only to...

  6. 45 CFR 2400.54 - Use of stipend.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Use of stipend. 2400.54 Section 2400.54 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Fellowship Stipend § 2400.54 Use of stipend. Stipends shall be used only to...

  7. 27 CFR 18.54 - Transfer of concentrate.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Transfer of concentrate. 18.54 Section 18.54 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS PRODUCTION OF VOLATILE FRUIT-FLAVOR CONCENTRATE Operations § 18.54...

  8. 27 CFR 18.54 - Transfer of concentrate.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Transfer of concentrate. 18.54 Section 18.54 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL PRODUCTION OF VOLATILE FRUIT-FLAVOR CONCENTRATE Operations § 18.54...

  9. 27 CFR 18.54 - Transfer of concentrate.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Transfer of concentrate. 18.54 Section 18.54 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS PRODUCTION OF VOLATILE FRUIT-FLAVOR CONCENTRATE Operations § 18.54...

  10. 27 CFR 18.54 - Transfer of concentrate.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Transfer of concentrate. 18.54 Section 18.54 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS PRODUCTION OF VOLATILE FRUIT-FLAVOR CONCENTRATE Operations § 18.54...

  11. 46 CFR 111.54-3 - Remote control.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Remote control. 111.54-3 Section 111.54-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Circuit Breakers § 111.54-3 Remote control. Remotely controlled circuit breakers must have local...

  12. 46 CFR 111.54-3 - Remote control.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Remote control. 111.54-3 Section 111.54-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Circuit Breakers § 111.54-3 Remote control. Remotely controlled circuit breakers must have local...

  13. 46 CFR 111.54-3 - Remote control.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Remote control. 111.54-3 Section 111.54-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Circuit Breakers § 111.54-3 Remote control. Remotely controlled circuit breakers must have local...

  14. 46 CFR 111.54-3 - Remote control.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Remote control. 111.54-3 Section 111.54-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Circuit Breakers § 111.54-3 Remote control. Remotely controlled circuit breakers must have local...

  15. 46 CFR 111.54-3 - Remote control.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Remote control. 111.54-3 Section 111.54-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Circuit Breakers § 111.54-3 Remote control. Remotely controlled circuit breakers must have local...

  16. 38 CFR 4.47-4.54 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false [Reserved] 4.47-4.54 Section 4.47-4.54 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS SCHEDULE FOR RATING DISABILITIES Disability Ratings The Musculoskeletal System §§ 4.47-4.54 [Reserved] ...

  17. 38 CFR 4.47-4.54 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2012-07-01 2012-07-01 false [Reserved] 4.47-4.54 Section 4.47-4.54 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS SCHEDULE FOR RATING DISABILITIES Disability Ratings The Musculoskeletal System §§ 4.47-4.54 [Reserved] ...

  18. 38 CFR 4.47-4.54 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false [Reserved] 4.47-4.54 Section 4.47-4.54 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS SCHEDULE FOR RATING DISABILITIES Disability Ratings The Musculoskeletal System §§ 4.47-4.54 [Reserved] ...

  19. 38 CFR 4.47-4.54 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false [Reserved] 4.47-4.54 Section 4.47-4.54 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS SCHEDULE FOR RATING DISABILITIES Disability Ratings The Musculoskeletal System §§ 4.47-4.54 [Reserved] ...

  20. 38 CFR 4.47-4.54 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false [Reserved] 4.47-4.54 Section 4.47-4.54 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS SCHEDULE FOR RATING DISABILITIES Disability Ratings The Musculoskeletal System §§ 4.47-4.54 [Reserved] ...

  1. 1 CFR 5.4 - Publication not authorized.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Publication not authorized. 5.4 Section 5.4 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.4 Publication not authorized. (a) Chapter 15 of title 44, United States Code, does not apply to treaties...

  2. 1 CFR 5.4 - Publication not authorized.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Publication not authorized. 5.4 Section 5.4 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.4 Publication not authorized. (a) Chapter 15 of title 44, United States Code, does not apply to treaties...

  3. 49 CFR 386.54 - Administrative Law Judge.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 5 2011-10-01 2011-10-01 false Administrative Law Judge. 386.54 Section 386.54... General Rules and Hearings § 386.54 Administrative Law Judge. (a) Powers of an Administrative Law Judge. The Administrative Law Judge may take any action and may prescribe all necessary rules and regulations...

  4. 49 CFR 386.54 - Administrative Law Judge.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 5 2013-10-01 2013-10-01 false Administrative Law Judge. 386.54 Section 386.54... General Rules and Hearings § 386.54 Administrative Law Judge. (a) Powers of an Administrative Law Judge. The Administrative Law Judge may take any action and may prescribe all necessary rules and regulations...

  5. 7 CFR 2902.54 - Heat transfer fluids.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false Heat transfer fluids. 2902.54 Section 2902.54... Items § 2902.54 Heat transfer fluids. (a) Definition. Products with high thermal capacities used to facilitate the transfer of heat from one location to another, including coolants or refrigerants for use in...

  6. 49 CFR 386.54 - Administrative Law Judge.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Administrative Law Judge. 386.54 Section 386.54... General Rules and Hearings § 386.54 Administrative Law Judge. (a) Powers of an Administrative Law Judge. The Administrative Law Judge may take any action and may prescribe all necessary rules and regulations...

  7. 47 CFR 17.54 - Rated lamp voltage.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Rated lamp voltage. 17.54 Section 17.54... STRUCTURES Specifications for Obstruction Marking and Lighting of Antenna Structures § 17.54 Rated lamp... lamps used shall correspond to be within 3 percent higher than the voltage across the lamp socket during...

  8. 47 CFR 17.54 - Rated lamp voltage.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Rated lamp voltage. 17.54 Section 17.54... STRUCTURES Specifications for Obstruction Marking and Lighting of Antenna Structures § 17.54 Rated lamp... lamps used shall correspond to be within 3 percent higher than the voltage across the lamp socket during...

  9. 47 CFR 17.54 - Rated lamp voltage.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Rated lamp voltage. 17.54 Section 17.54... STRUCTURES Specifications for Obstruction Marking and Lighting of Antenna Structures § 17.54 Rated lamp... lamps used shall correspond to be within 3 percent higher than the voltage across the lamp socket during...

  10. 47 CFR 17.54 - Rated lamp voltage.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Rated lamp voltage. 17.54 Section 17.54... STRUCTURES Specifications for Obstruction Marking and Lighting of Antenna Structures § 17.54 Rated lamp... lamps used shall correspond to be within 3 percent higher than the voltage across the lamp socket during...

  11. 47 CFR 17.54 - Rated lamp voltage.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Rated lamp voltage. 17.54 Section 17.54... STRUCTURES Specifications for Obstruction Marking and Lighting of Antenna Structures § 17.54 Rated lamp... lamps used shall correspond to be within 3 percent higher than the voltage across the lamp socket during...

  12. 27 CFR 478.54 - Change of control.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2010-04-01 2010-04-01 false Change of control. 478.54 Section 478.54 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND....54 Change of control. In the case of a corporation or association holding a license under this part...

  13. 1 CFR 5.4 - Publication not authorized.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Publication not authorized. 5.4 Section 5.4 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.4 Publication not authorized. (a) Chapter 15 of title 44, United States Code, does not apply to treaties...

  14. The N54-αs Mutant Has Decreased Affinity for βγ and Suggests a Mechanism for Coupling Heterotrimeric G Protein Nucleotide Exchange with Subunit Dissociation.

    PubMed

    Cleator, John H; Wells, Christopher A; Dingus, Jane; Kurtz, David T; Hildebrandt, John D

    2018-05-01

    Ser54 of G s α binds guanine nucleotide and Mg 2+ as part of a conserved sequence motif in GTP binding proteins. Mutating the homologous residue in small and heterotrimeric G proteins generates dominant-negative proteins, but by protein-specific mechanisms. For α i/o , this results from persistent binding of α to βγ , whereas for small GTP binding proteins and α s this results from persistent binding to guanine nucleotide exchange factor or receptor. This work examined the role of βγ interactions in mediating the properties of the Ser54-like mutants of G α subunits. Unexpectedly, WT- α s or N54- α s coexpressed with α 1B -adrenergic receptor in human embryonic kidney 293 cells decreased receptor stimulation of IP3 production by a cAMP-independent mechanism, but WT- α s was more effective than the mutant. One explanation for this result would be that α s , like Ser47 α i/o , blocks receptor activation by sequestering βγ ; implying that N54- α S has reduced affinity for βγ since it was less effective at blocking IP3 production. This possibility was more directly supported by the observation that WT- α s was more effective than the mutant in inhibiting βγ activation of phospholipase C β 2. Further, in vitro synthesized N54- α s bound biotinylated- βγ with lower apparent affinity than did WT- α s The Cys54 mutation also decreased βγ binding but less effectively than N54- α s Substitution of the conserved Ser in α o with Cys or Asn increased βγ binding, with the Cys mutant being more effective. This suggests that Ser54 of α s is involved in coupling changes in nucleotide binding with altered subunit interactions, and has important implications for how receptors activate G proteins. Copyright © 2018 by The American Society for Pharmacology and Experimental Therapeutics.

  15. 47 CFR 54.800 - Terms and definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Terms and definitions. 54.800 Section 54.800... SERVICE Interstate Access Universal Service Support Mechanism § 54.800 Terms and definitions. (a) Average... § 61.3(d) of this chapter, except that it includes exogenous changes in effect prior to the effective...

  16. 12 CFR 239.54 - Plan of conversion.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 4 2012-01-01 2012-01-01 false Plan of conversion. 239.54 Section 239.54 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Conversions from Mutual to Stock Form § 239.54 Plan of...

  17. 12 CFR 239.54 - Plan of conversion.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 4 2013-01-01 2013-01-01 false Plan of conversion. 239.54 Section 239.54 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Conversions From Mutual to Stock Form § 239.54 Plan of...

  18. 12 CFR 239.54 - Plan of conversion.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Plan of conversion. 239.54 Section 239.54 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Conversions From Mutual to Stock Form § 239.54 Plan of...

  19. 45 CFR 702.54 - Closed meeting procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Closed meeting procedures. 702.54 Section 702.54... HEARINGS, REPORTS, AND MEETINGS OF THE COMMISSION Meetings § 702.54 Closed meeting procedures. (a) A meeting or portion thereof will be closed, and information pertaining to a closed meeting will be withheld...

  20. Expedition 54 Soyuz Docking

    NASA Image and Video Library

    2017-12-19

    NASA International Space Station Program Manager Kirk Shireman speaks with the Expedition 54 crew from the Moscow Mission Control Center in Korolev, Russia a few hours after the Soyuz MS-07 docked to the International Space Station on Tuesday, Dec. 19, 2017. Hatches were opened at 5:55 a.m. EST and Anton Shkaplerov of Roscosmos, Scott Tingle of NASA, and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) joined Expedition 54 Commander Alexander Misurkin of Roscosmos and crewmates Mark Vande Hei and Joe Acaba of NASA aboard the orbiting laboratory. Photo Credit: (NASA/Joel Kowsky)

  1. Expedition 54 Soyuz Docking

    NASA Image and Video Library

    2017-12-19

    Japan Aerospace Exploration Agency (JAXA) International Space Station Program Manager Koichi Wakata speaks with the Expedition 54 crew from the Moscow Mission Control Center in Korolev, Russia a few hours after the Soyuz MS-07 docked to the International Space Station on Tuesday, Dec. 19, 2017. Hatches were opened at 5:55 a.m. EST and Anton Shkaplerov of Roscosmos, Scott Tingle of NASA, and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) joined Expedition 54 Commander Alexander Misurkin of Roscosmos and crewmates Mark Vande Hei and Joe Acaba of NASA aboard the orbiting laboratory. Photo Credit: (NASA/Joel Kowsky)

  2. Mutations in SRP54 gene cause severe congenital neutropenia as well as Shwachman-Diamond-like syndrome.

    PubMed

    Bellanné-Chantelot, Christine; Schmaltz-Panneau, Barbara; Marty, Caroline; Fenneteau, Odile; Callebaut, Isabelle; Clauin, Séverine; Docet, Aurélie; Damaj, Gandhi-Laurent; Leblanc, Thierry; Pellier, Isabelle; Stoven, Cécile; Souquere, Sylvie; Antony-Debré, Iléana; Beaupain, Blandine; Aladjidi, Nathalie; Barlogis, Vincent; Bauduer, Frédéric; Bensaid, Philippe; Boespflug-Tanguy, Odile; Berger, Claire; Bertrand, Yves; Carausu, Liana; Fieschi, Claire; Galambrun, Claire; Schmidt, Aline; Journel, Hubert; Mazingue, Françoise; Nelken, Brigitte; Quah, Thuan Chong; Oksenhendler, Eric; Ouachée, Marie; Pasquet, Marlène; Saada, Véronique; Suarez, Felipe; Pierron, Gérard; Vainchenker, William; Plo, Isabelle; Donadieu, Jean

    2018-06-18

    Congenital neutropenias (CN) are rare heterogeneous genetic disorders with about 25% of patients without known genetic defects. Using whole-exome sequencing, we identified a heterozygous mutation in the SRP54 gene, encoding the signal recognition particle (SRP) 54 GTPase protein, in 3 sporadic cases and one autosomal dominant family. We subsequently sequenced the SRP54 gene in 66 probands from the French CN registry. In total, we identified 23 mutated cases (16 sporadic, 7 familial) with seven distinct germline SRP54 mutations including a recurrent in-frame deletion (Thr117del) in 14 cases. In nearly all patients, neutropenia was chronic and profound with promyelocytic maturation arrest, occurring within the first months of life and required long-term G-CSF therapy with a poor response. Neutropenia was sometimes associated with a severe neurodevelopmental delay (n=5) and/or an exocrine pancreatic insufficiency requiring enzyme supplementation (n=3) The SRP54 protein is a key component of the ribonucleoprotein complex that mediates the co-translational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). We showed that SRP54 was specifically upregulated during the in vitro granulocytic differentiation and that SRP54 mutations or knockdown led to a drastically reduced proliferation of granulocytic cells associated with an enhanced P53-dependent apoptosis. Bone marrow examination of SRP54 -mutated patients revealed a major dysgranulopoiesis and features of cellular ER stress and autophagy that were confirmed using SRP54 -mutated primary cells and SRP54 knockdown cells. In conclusion, we characterized a pathological pathway, which represents the second most common cause of CN with maturation arrest in the French CN registry. Copyright © 2018 American Society of Hematology.

  3. 42 CFR 433.54 - Bona fide donations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Bona fide donations. 433.54 Section 433.54 Public... Financial Participation § 433.54 Bona fide donations. (a) A bona fide donation means a provider-related donation, as defined in § 433.52, made to the State or unit of local government, that has no direct or...

  4. 46 CFR 502.54 - Contents of rules.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 9 2013-10-01 2013-10-01 false Contents of rules. 502.54 Section 502.54 Shipping FEDERAL MARITIME COMMISSION GENERAL AND ADMINISTRATIVE PROVISIONS RULES OF PRACTICE AND PROCEDURE Rulemaking § 502.54 Contents of rules. The Commission will incorporate in any publication of proposed or final rules a concise and general statement of their...

  5. 42 CFR 433.54 - Bona fide donations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Bona fide donations. 433.54 Section 433.54 Public... Financial Participation § 433.54 Bona fide donations. (a) A bona fide donation means a provider-related donation, as defined in § 433.52, made to the State or unit of local government, that has no direct or...

  6. 42 CFR 433.54 - Bona fide donations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Bona fide donations. 433.54 Section 433.54 Public... Financial Participation § 433.54 Bona fide donations. (a) A bona fide donation means a provider-related donation, as defined in § 433.52, made to the State or unit of local government, that has no direct or...

  7. 42 CFR 433.54 - Bona fide donations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Bona fide donations. 433.54 Section 433.54 Public... Financial Participation § 433.54 Bona fide donations. (a) A bona fide donation means a provider-related donation, as defined in § 433.52, made to the State or unit of local government, that has no direct or...

  8. 7 CFR 1794.54 - Agency determination.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 12 2013-01-01 2013-01-01 false Agency determination. 1794.54 Section 1794.54 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Procedure for Environmental Assessments With...

  9. 7 CFR 1794.54 - Agency determination.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 12 2011-01-01 2011-01-01 false Agency determination. 1794.54 Section 1794.54 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Procedure for Environmental Assessments With...

  10. 7 CFR 1794.54 - Agency determination.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 12 2012-01-01 2012-01-01 false Agency determination. 1794.54 Section 1794.54 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Procedure for Environmental Assessments With...

  11. 7 CFR 1794.54 - Agency determination.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 12 2014-01-01 2013-01-01 true Agency determination. 1794.54 Section 1794.54 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Procedure for Environmental Assessments With...

  12. 7 CFR 1794.54 - Agency determination.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Agency determination. 1794.54 Section 1794.54 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Procedure for Environmental Assessments With...

  13. Visualization of the African swine fever virus infection in living cells by incorporation into the virus particle of green fluorescent protein-p54 membrane protein chimera

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hernaez, Bruno; Escribano, Jose M.; Alonso, Covadonga

    2006-06-20

    Many stages of African swine fever virus infection have not yet been studied in detail. To track the behavior of African swine fever virus (ASFV) in the infected cells in real time, we produced an infectious recombinant ASFV (B54GFP-2) that expresses and incorporates into the virus particle a chimera of the p54 envelope protein fused to the enhanced green fluorescent protein (EGFP). The incorporation of the fusion protein into the virus particle was confirmed immunologically and it was determined that p54-EGFP was fully functional by confirmation that the recombinant virus made normal-sized plaques and presented similar growth curves to themore » wild-type virus. The tagged virus was visualized as individual fluorescent particles during the first stages of infection and allowed to visualize the infection progression in living cells through the viral life cycle by confocal microscopy. In this work, diverse potential applications of B54GFP-2 to study different aspects of ASFV infection are shown. By using this recombinant virus it was possible to determine the trajectory and speed of intracellular virus movement. Additionally, we have been able to visualize for first time the ASFV factory formation dynamics and the cytophatic effect of the virus in live infected cells. Finally, we have analyzed virus progression along the infection cycle and infected cell death as time-lapse animations.« less

  14. 28 CFR 41.54 - Employment criteria.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Employment criteria. 41.54 Section 41.54 Judicial Administration DEPARTMENT OF JUSTICE IMPLEMENTATION OF EXECUTIVE ORDER 12250, NONDISCRIMINATION ON THE BASIS OF HANDICAP IN FEDERALLY ASSISTED PROGRAMS Guidelines for Determining Discriminatory...

  15. 28 CFR 41.54 - Employment criteria.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Employment criteria. 41.54 Section 41.54 Judicial Administration DEPARTMENT OF JUSTICE IMPLEMENTATION OF EXECUTIVE ORDER 12250, NONDISCRIMINATION ON THE BASIS OF HANDICAP IN FEDERALLY ASSISTED PROGRAMS Guidelines for Determining Discriminatory...

  16. 28 CFR 41.54 - Employment criteria.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Employment criteria. 41.54 Section 41.54 Judicial Administration DEPARTMENT OF JUSTICE IMPLEMENTATION OF EXECUTIVE ORDER 12250, NONDISCRIMINATION ON THE BASIS OF HANDICAP IN FEDERALLY ASSISTED PROGRAMS Guidelines for Determining Discriminatory...

  17. 28 CFR 41.54 - Employment criteria.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Employment criteria. 41.54 Section 41.54 Judicial Administration DEPARTMENT OF JUSTICE IMPLEMENTATION OF EXECUTIVE ORDER 12250, NONDISCRIMINATION ON THE BASIS OF HANDICAP IN FEDERALLY ASSISTED PROGRAMS Guidelines for Determining Discriminatory...

  18. 28 CFR 41.54 - Employment criteria.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Employment criteria. 41.54 Section 41.54 Judicial Administration DEPARTMENT OF JUSTICE IMPLEMENTATION OF EXECUTIVE ORDER 12250, NONDISCRIMINATION ON THE BASIS OF HANDICAP IN FEDERALLY ASSISTED PROGRAMS Guidelines for Determining Discriminatory...

  19. 47 CFR 54.604 - Existing contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Health Care Providers § 54.604 Existing contracts. (a) Existing... health care provider as defined under § 54.601 and a telecommunications carrier shall be exempt from the...

  20. 7 CFR 3430.54 - Indirect costs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false Indirect costs. 3430.54 Section 3430.54 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE COMPETITIVE AND NONCOMPETITIVE NON-FORMULA FEDERAL ASSISTANCE PROGRAMS-GENERAL AWARD ADMINISTRATIVE PROVISIONS...

  1. 29 CFR 1926.54 - Nonionizing radiation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 8 2010-07-01 2010-07-01 false Nonionizing radiation. 1926.54 Section 1926.54 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Occupational Health and Environmental Controls...

  2. 28 CFR 54.605 - Enforcement procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Enforcement procedures. 54.605 Section 54.605 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN... procedures. The investigative, compliance, and enforcement procedural provisions of Title VI of the Civil...

  3. 28 CFR 54.605 - Enforcement procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Enforcement procedures. 54.605 Section 54.605 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN... procedures. The investigative, compliance, and enforcement procedural provisions of Title VI of the Civil...

  4. 28 CFR 54.605 - Enforcement procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Enforcement procedures. 54.605 Section 54.605 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN... procedures. The investigative, compliance, and enforcement procedural provisions of Title VI of the Civil...

  5. 28 CFR 54.605 - Enforcement procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Enforcement procedures. 54.605 Section 54.605 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN... procedures. The investigative, compliance, and enforcement procedural provisions of Title VI of the Civil...

  6. 28 CFR 54.605 - Enforcement procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Enforcement procedures. 54.605 Section 54.605 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN... procedures. The investigative, compliance, and enforcement procedural provisions of Title VI of the Civil...

  7. 40 CFR 204.54 - Test procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... frequency response calibration and an attenuator (gain control) calibration plus a measurement of dynamic... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Test procedures. 204.54 Section 204.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS NOISE EMISSION...

  8. 7 CFR 1001.54 - Equivalent price.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Equivalent price. 1001.54 Section 1001.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE NORTHEAST MARKETING AREA Order Regulating...

  9. 49 CFR 195.54 - Accident reports.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Accident reports. 195.54 Section 195.54 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Annual, Accident, and...

  10. 21 CFR 1316.54 - Prehearing conference.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Prehearing conference. 1316.54 Section 1316.54 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE ADMINISTRATIVE FUNCTIONS... to be called. (e) The advance submission at the prehearing conference of all documentary evidence and...

  11. 42 CFR 54.6 - Employment practices.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Employment practices. 54.6 Section 54.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE REGULATIONS APPLICABLE TO STATES RECEIVING SUBSTANCE ABUSE PREVENTION AND TREATMENT BLOCK GRANTS AND/OR...

  12. 42 CFR 54.4 - Religious activities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Religious activities. 54.4 Section 54.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE REGULATIONS APPLICABLE TO STATES RECEIVING SUBSTANCE ABUSE PREVENTION AND TREATMENT BLOCK GRANTS AND/OR...

  13. 42 CFR 54.6 - Employment practices.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Employment practices. 54.6 Section 54.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE REGULATIONS APPLICABLE TO STATES RECEIVING SUBSTANCE ABUSE PREVENTION AND TREATMENT BLOCK GRANTS AND/OR...

  14. 42 CFR 54.4 - Religious activities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Religious activities. 54.4 Section 54.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE REGULATIONS APPLICABLE TO STATES RECEIVING SUBSTANCE ABUSE PREVENTION AND TREATMENT BLOCK GRANTS AND/OR...

  15. 42 CFR 54.4 - Religious activities.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Religious activities. 54.4 Section 54.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE REGULATIONS APPLICABLE TO STATES RECEIVING SUBSTANCE ABUSE PREVENTION AND TREATMENT BLOCK GRANTS AND/OR...

  16. 42 CFR 54.6 - Employment practices.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Employment practices. 54.6 Section 54.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE REGULATIONS APPLICABLE TO STATES RECEIVING SUBSTANCE ABUSE PREVENTION AND TREATMENT BLOCK GRANTS AND/OR...

  17. 42 CFR 54.6 - Employment practices.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Employment practices. 54.6 Section 54.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE REGULATIONS APPLICABLE TO STATES RECEIVING SUBSTANCE ABUSE PREVENTION AND TREATMENT BLOCK GRANTS AND/OR...

  18. 42 CFR 54.6 - Employment practices.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Employment practices. 54.6 Section 54.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE REGULATIONS APPLICABLE TO STATES RECEIVING SUBSTANCE ABUSE PREVENTION AND TREATMENT BLOCK GRANTS AND/OR...

  19. 42 CFR 54.4 - Religious activities.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Religious activities. 54.4 Section 54.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE REGULATIONS APPLICABLE TO STATES RECEIVING SUBSTANCE ABUSE PREVENTION AND TREATMENT BLOCK GRANTS AND/OR...

  20. 42 CFR 54.4 - Religious activities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Religious activities. 54.4 Section 54.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE REGULATIONS APPLICABLE TO STATES RECEIVING SUBSTANCE ABUSE PREVENTION AND TREATMENT BLOCK GRANTS AND/OR...

  1. 46 CFR 54.03-5 - General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false General. 54.03-5 Section 54.03-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Low Temperature Operation... minimum service temperature may be used in warmer service. Steels differing in chemical composition...

  2. 46 CFR 54.03-5 - General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false General. 54.03-5 Section 54.03-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Low Temperature Operation... minimum service temperature may be used in warmer service. Steels differing in chemical composition...

  3. 46 CFR 54.03-5 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false General. 54.03-5 Section 54.03-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Low Temperature Operation... minimum service temperature may be used in warmer service. Steels differing in chemical composition...

  4. 46 CFR 54.03-5 - General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false General. 54.03-5 Section 54.03-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Low Temperature Operation... minimum service temperature may be used in warmer service. Steels differing in chemical composition...

  5. 46 CFR 54.03-5 - General.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false General. 54.03-5 Section 54.03-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Low Temperature Operation... minimum service temperature may be used in warmer service. Steels differing in chemical composition...

  6. 7 CFR 15a.54 - Compensation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Compensation. 15a.54 Section 15a.54 Agriculture Office of the Secretary of Agriculture EDUCATION PROGRAMS OR ACTIVITIES RECEIVING OR BENEFITTING FROM FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs and...

  7. 41 CFR 105-54.301 - Meetings.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Meetings. 105-54.301 Section 105-54.301 Public Contracts and Property Management Federal Property Management Regulations System... committee meeting is open to the public unless the Administrator decides otherwise; (b) Each meeting is held...

  8. 41 CFR 105-54.301 - Meetings.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Meetings. 105-54.301 Section 105-54.301 Public Contracts and Property Management Federal Property Management Regulations System... committee meeting is open to the public unless the Administrator decides otherwise; (b) Each meeting is held...

  9. 47 CFR 54.643 - Funding commitments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... SERVICE Universal Service Support for Health Care Providers Healthcare Connect Fund § 54.643 Funding... belief, the most cost-effective vendor available, as defined in § 54.642(c). (iii) All Healthcare Connect... support for the same service from both the Telecommunications Program and the Healthcare Connect Fund. (v...

  10. 47 CFR 54.643 - Funding commitments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SERVICE Universal Service Support for Health Care Providers Healthcare Connect Fund § 54.643 Funding... belief, the most cost-effective vendor available, as defined in § 54.642(c). (iii) All Healthcare Connect... support for the same service from both the Telecommunications Program and the Healthcare Connect Fund. (v...

  11. 42 CFR 54a.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... financial assistance under an applicable program. (e) SAMHSA means the Substance Abuse and Mental Health... 42 Public Health 1 2010-10-01 2010-10-01 false Definitions. 54a.2 Section 54a.2 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE REGULATIONS...

  12. 42 CFR 54.7 - Nondiscrimination requirement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Nondiscrimination requirement. 54.7 Section 54.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE... program beneficiary on the basis of religion, a religious belief, a refusal to hold a religious belief, or...

  13. 42 CFR 54.7 - Nondiscrimination requirement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Nondiscrimination requirement. 54.7 Section 54.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE... program beneficiary on the basis of religion, a religious belief, a refusal to hold a religious belief, or...

  14. 42 CFR 54.7 - Nondiscrimination requirement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Nondiscrimination requirement. 54.7 Section 54.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE... program beneficiary on the basis of religion, a religious belief, a refusal to hold a religious belief, or...

  15. 42 CFR 54.7 - Nondiscrimination requirement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Nondiscrimination requirement. 54.7 Section 54.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE... program beneficiary on the basis of religion, a religious belief, a refusal to hold a religious belief, or...

  16. 42 CFR 54.7 - Nondiscrimination requirement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Nondiscrimination requirement. 54.7 Section 54.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE... program beneficiary on the basis of religion, a religious belief, a refusal to hold a religious belief, or...

  17. 33 CFR 62.54 - Ownership identification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Section 62.54 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY AIDS TO NAVIGATION UNITED STATES AIDS TO NAVIGATION SYSTEM The U.S. Aids to Navigation System § 62.54 Ownership identification. Ownership identification on private or state aids to navigation is permitted so long as it does...

  18. 33 CFR 62.54 - Ownership identification.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Section 62.54 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY AIDS TO NAVIGATION UNITED STATES AIDS TO NAVIGATION SYSTEM The U.S. Aids to Navigation System § 62.54 Ownership identification. Ownership identification on private or state aids to navigation is permitted so long as it does...

  19. 33 CFR 62.54 - Ownership identification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Section 62.54 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY AIDS TO NAVIGATION UNITED STATES AIDS TO NAVIGATION SYSTEM The U.S. Aids to Navigation System § 62.54 Ownership identification. Ownership identification on private or state aids to navigation is permitted so long as it does...

  20. 33 CFR 62.54 - Ownership identification.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Section 62.54 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY AIDS TO NAVIGATION UNITED STATES AIDS TO NAVIGATION SYSTEM The U.S. Aids to Navigation System § 62.54 Ownership identification. Ownership identification on private or state aids to navigation is permitted so long as it does...

  1. 33 CFR 62.54 - Ownership identification.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Section 62.54 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY AIDS TO NAVIGATION UNITED STATES AIDS TO NAVIGATION SYSTEM The U.S. Aids to Navigation System § 62.54 Ownership identification. Ownership identification on private or state aids to navigation is permitted so long as it does...

  2. 9 CFR 113.54 - Sterile diluent.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Sterile diluent. 113.54 Section 113.54 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES... acceptable outline on file with Animal and Plant Health Inspection Service. (b) Each quantity prepared at one...

  3. Expedition 54 Soyuz Docking

    NASA Image and Video Library

    2017-12-19

    Scott Tingle of NASA is seen embracing Expedition 54 Commander Alexander Misurkin after the opening of the hatches between the Soyuz MS-07 spacecraft and the International Space Station on the screens in the Moscow Mission Control Center in Korolev, Russia a few hours after the Soyuz MS-07 docked to the International Space Station on Tuesday, Dec. 19, 2017. Hatches were opened at 5:55 a.m. EST and Tingle, Anton Shkaplerov of Roscosmos, and Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) joined Expedition 54 Commander Alexander Misurkin of Roscosmos and crewmates Mark Vande Hei and Joe Acaba of NASA aboard the orbiting laboratory. Photo Credit: (NASA/Joel Kowsky)

  4. σ 54-dependent regulome in Desulfovibrio vulgaris Hildenborough

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kazakov, Alexey E.; Rajeev, Lara; Chen, Amy

    2015-11-10

    The σ 54 subunit controls a unique class of promoters in bacteria. Such promoters, without exception, require enhancer binding proteins (EBPs) for transcription initiation. Desulfovibrio vulgaris Hildenborough, a model bacterium for sulfate reduction studies, has a high number of EBPs, more than most sequenced bacteria. Finally, the cellular processes regulated by many of these EBPs remain unknown.

  5. 47 CFR 54.514 - Payment for discounted service.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false Payment for discounted service. 54.514 Section 54.514 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Schools and Libraries § 54.514 Payment for...

  6. 47 CFR 54.514 - Payment for discounted service.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Payment for discounted service. 54.514 Section 54.514 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Schools and Libraries § 54.514 Payment for...

  7. Radon Sampling, Building 54, Nellis AFB, NV

    DTIC Science & Technology

    2012-07-13

    BEF) performed radon testing in response to a concern of elevated radon levels in Building 54. The building was previously remediated to reduce the... TESTING METHODOLOGY: a. Test Scenario: Building 54 was chosen to test for radon gas levels. Radon detectors were placed in the test ...Consultative Letter 3. DATES COVERED (From – To) 22-24 March 2012 4. TITLE AND SUBTITLE Radon Sampling, Building 54, Nellis AFB, NV 5a. CONTRACT

  8. 25 CFR 5.4 - Information collection.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Information collection. 5.4 Section 5.4 Indians BUREAU OF... Information collection. The Office of Management and Budget has informed the Department of the Interior that the information collection requirements contained in part 5 need not be reviewed by them under the...

  9. 25 CFR 5.4 - Information collection.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Information collection. 5.4 Section 5.4 Indians BUREAU OF... Information collection. The Office of Management and Budget has informed the Department of the Interior that the information collection requirements contained in part 5 need not be reviewed by them under the...

  10. 45 CFR 605.54 - Education of institutionalized persons.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Education of institutionalized persons. 605.54 Section 605.54 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... ASSISTANCE Health, Welfare, and Social Services § 605.54 Education of institutionalized persons. A recipient...

  11. 45 CFR 605.54 - Education of institutionalized persons.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Education of institutionalized persons. 605.54 Section 605.54 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... ASSISTANCE Health, Welfare, and Social Services § 605.54 Education of institutionalized persons. A recipient...

  12. 45 CFR 605.54 - Education of institutionalized persons.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Education of institutionalized persons. 605.54 Section 605.54 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... ASSISTANCE Health, Welfare, and Social Services § 605.54 Education of institutionalized persons. A recipient...

  13. 40 CFR 467.54 - New source performance standards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false New source performance standards. 467.54 Section 467.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ALUMINUM FORMING POINT SOURCE CATEGORY Drawing With Neat Oils Subcategory § 467.54...

  14. 28 CFR 54.130 - Effect of employment opportunities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Effect of employment opportunities. 54.130 Section 54.130 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE... § 54.130 Effect of employment opportunities. The obligation to comply with these Title IX regulations...

  15. 42 CFR 54a.1 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... 290aa, et seq., which are administered by the Substance Abuse and Mental Health Services Administration. This part does not apply to direct funding under any such authorities for only mental health services... 42 Public Health 1 2010-10-01 2010-10-01 false Scope. 54a.1 Section 54a.1 Public Health PUBLIC...

  16. 42 CFR 54a.1 - Scope.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... 290aa, et seq., which are administered by the Substance Abuse and Mental Health Services Administration. This part does not apply to direct funding under any such authorities for only mental health services... 42 Public Health 1 2014-10-01 2014-10-01 false Scope. 54a.1 Section 54a.1 Public Health PUBLIC...

  17. 42 CFR 54a.1 - Scope.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... 290aa, et seq., which are administered by the Substance Abuse and Mental Health Services Administration. This part does not apply to direct funding under any such authorities for only mental health services... 42 Public Health 1 2012-10-01 2012-10-01 false Scope. 54a.1 Section 54a.1 Public Health PUBLIC...

  18. 42 CFR 54a.1 - Scope.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    .... 290aa, et seq., which are administered by the Substance Abuse and Mental Health Services Administration. This part does not apply to direct funding under any such authorities for only mental health services... 42 Public Health 1 2011-10-01 2011-10-01 false Scope. 54a.1 Section 54a.1 Public Health PUBLIC...

  19. 42 CFR 54a.1 - Scope.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    .... 290aa, et seq., which are administered by the Substance Abuse and Mental Health Services Administration. This part does not apply to direct funding under any such authorities for only mental health services... 42 Public Health 1 2013-10-01 2013-10-01 false Scope. 54a.1 Section 54a.1 Public Health PUBLIC...

  20. 34 CFR 104.54 - Education of institutionalized persons.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 1 2011-07-01 2011-07-01 false Education of institutionalized persons. 104.54 Section 104.54 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS... FEDERAL FINANCIAL ASSISTANCE Health, Welfare, and Social Services § 104.54 Education of institutionalized...

  1. 34 CFR 104.54 - Education of institutionalized persons.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false Education of institutionalized persons. 104.54 Section 104.54 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS... FEDERAL FINANCIAL ASSISTANCE Health, Welfare, and Social Services § 104.54 Education of institutionalized...

  2. 34 CFR 104.54 - Education of institutionalized persons.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 1 2014-07-01 2014-07-01 false Education of institutionalized persons. 104.54 Section 104.54 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS... FEDERAL FINANCIAL ASSISTANCE Health, Welfare, and Social Services § 104.54 Education of institutionalized...

  3. 34 CFR 104.54 - Education of institutionalized persons.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 1 2013-07-01 2013-07-01 false Education of institutionalized persons. 104.54 Section 104.54 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS... FEDERAL FINANCIAL ASSISTANCE Health, Welfare, and Social Services § 104.54 Education of institutionalized...

  4. 28 CFR 550.54 - Incentives for RDAP participation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Incentives for RDAP participation. 550.54 Section 550.54 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT DRUG PROGRAMS Drug Abuse Treatment Program § 550.54 Incentives for RDAP participation. (a) An inmate...

  5. 28 CFR 550.54 - Incentives for RDAP participation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Incentives for RDAP participation. 550.54 Section 550.54 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT DRUG PROGRAMS Drug Abuse Treatment Program § 550.54 Incentives for RDAP participation. (a) An inmate...

  6. 28 CFR 550.54 - Incentives for RDAP participation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Incentives for RDAP participation. 550.54 Section 550.54 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT DRUG PROGRAMS Drug Abuse Treatment Program § 550.54 Incentives for RDAP participation. (a) An inmate...

  7. 28 CFR 550.54 - Incentives for RDAP participation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Incentives for RDAP participation. 550.54 Section 550.54 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT DRUG PROGRAMS Drug Abuse Treatment Program § 550.54 Incentives for RDAP participation. (a) An inmate...

  8. 28 CFR 550.54 - Incentives for RDAP participation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Incentives for RDAP participation. 550.54 Section 550.54 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT DRUG PROGRAMS Drug Abuse Treatment Program § 550.54 Incentives for RDAP participation. (a) An inmate...

  9. 40 CFR 264.54 - Amendment of contingency plan.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Amendment of contingency plan. 264.54 Section 264.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... Contingency Plan and Emergency Procedures § 264.54 Amendment of contingency plan. The contingency plan must be...

  10. 40 CFR 61.54 - Sludge sampling.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 8 2011-07-01 2011-07-01 false Sludge sampling. 61.54 Section 61.54... sampling. (a) As an alternative means for demonstrating compliance with § 61.52(b), an owner or operator... days prior to a sludge sampling test, so that he may at his option observe the test. (c) Sludge shall...

  11. 40 CFR 61.54 - Sludge sampling.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Sludge sampling. 61.54 Section 61.54... sampling. (a) As an alternative means for demonstrating compliance with § 61.52(b), an owner or operator... days prior to a sludge sampling test, so that he may at his option observe the test. (c) Sludge shall...

  12. 28 CFR 16.54 - Employee standards of conduct.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Employee standards of conduct. 16.54 Section 16.54 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Protection of Privacy and Access to Individual Records Under the Privacy Act of 1974 § 16.54...

  13. Regulation of Nucleocytoplasmic Shuttling of Bruton's Tyrosine Kinase (Btk) through a Novel SH3-Dependent Interaction with Ankyrin Repeat Domain 54 (ANKRD54)

    PubMed Central

    Hussain, Alamdar; Mohammad, Dara K.; Mohamed, Abdalla J.; Nguyen, Vivian; Metalnikov, Pavel; Colwill, Karen; Pawson, Tony; Nore, Beston F.

    2012-01-01

    Bruton's tyrosine kinase (Btk), belonging to the Tec family of tyrosine kinases (TFKs), is essential for B-lymphocyte development. Abrogation of Btk signaling causes human X-linked agammaglobulinemia (XLA) and murine X-linked immunodeficiency (Xid). We employed affinity purification of Flag-tagged Btk, combined with tandem mass spectrometry, to capture and identify novel interacting proteins. We here characterize the interaction with ankryin repeat domain 54 protein (ANKRD54), also known as Lyn-interacting ankyrin repeat protein (Liar). While Btk is a nucleocytoplasmic protein, the Liar pool was found to shuttle at a higher rate than Btk. Importantly, our results suggest that Liar mediates nuclear export of both Btk and another TFK, Txk/Rlk. Liar-mediated Btk shuttling was enriched for activation loop, nonphosphorylated Btk and entirely dependent on Btk's SH3 domain. Liar also showed reduced binding to an aspartic acid phosphomimetic SH3 mutant. Three other investigated nucleus-located proteins, Abl, estrogen receptor β (ERβ), and transcription factor T-bet, were all unaffected by Liar. We mapped the interaction site to the C terminus of the Btk SH3 domain. A biotinylated, synthetic Btk peptide, ARDKNGQEGYIPSNYVTEAEDS, was sufficient for this interaction. Liar is the first protein identified that specifically influences the nucleocytoplasmic shuttling of Btk and Txk and belongs to a rare group of known proteins carrying out this activity in a Crm1-dependent manner. PMID:22527282

  14. σ54-Dependent Response to Nitrogen Limitation and Virulence in Burkholderia cenocepacia Strain H111

    PubMed Central

    Lardi, Martina; Aguilar, Claudio; Pedrioli, Alessandro; Omasits, Ulrich; Suppiger, Angela; Cárcamo-Oyarce, Gerardo; Schmid, Nadine; Ahrens, Christian H.

    2015-01-01

    Members of the genus Burkholderia are versatile bacteria capable of colonizing highly diverse environmental niches. In this study, we investigated the global response of the opportunistic pathogen Burkholderia cenocepacia H111 to nitrogen limitation at the transcript and protein expression levels. In addition to a classical response to nitrogen starvation, including the activation of glutamine synthetase, PII proteins, and the two-component regulatory system NtrBC, B. cenocepacia H111 also upregulated polyhydroxybutyrate (PHB) accumulation and exopolysaccharide (EPS) production in response to nitrogen shortage. A search for consensus sequences in promoter regions of nitrogen-responsive genes identified a σ54 consensus sequence. The mapping of the σ54 regulon as well as the characterization of a σ54 mutant suggests an important role of σ54 not only in control of nitrogen metabolism but also in the virulence of this organism. PMID:25841012

  15. Developmental expression of the G protein-coupled receptor 54 and three GnRH mRNAs in the teleost fish cobia.

    PubMed

    Mohamed, J Shaik; Benninghoff, Abby D; Holt, G Joan; Khan, Izhar A

    2007-02-01

    The cDNAs of the G protein-coupled receptor 54 (GPR54) and three prepro-gonadotropin-releasing hormones, GnRH-I (seabream GnRH), GnRH-II (chicken GnRH-II), and GnRH-III (salmon GnRH) were isolated and cloned from the brain of the teleost fish cobia, Rachycentron canadum. The cobia GPR54 cDNA was 95 and 51-56% identical to those of tilapia and mammalian models respectively. The GnRH cDNA sequences of cobia showed strong identities to those of tilapia, Atlantic croaker, red drum, and the seabass and seabream species. The real-time quantitative RT-PCR methods allowed detection of all three GnRH mRNAs on the first day after hatching (DAH). The GnRH-I mRNA levels, which were the lowest among the three GnRHs, increased gradually with two distinct peaks in larvae at 3 and 4 DAH. On the other hand, GnRH-II and GnRH-III mRNAs were significantly higher in larvae at 2 and 6 DAH compared with those on the preceding days. In addition, significant peaks of all the three GnRH mRNAs were observed in the brains of 26-day-old fish. The finding of higher GnRH-I and GnRH-II mRNAs in males than females at 153 DAH may be related to early puberty observed during the first year in laboratory-reared male cobia. Moreover, this study demonstrates for the first time the expression of GPR54 mRNA during larval development in a vertebrate species. The concomitant expression patterns of GPR54 and GnRH mRNAs during different stages of larval and juvenile developments, and during early puberty in male cobia suggest a potential relationship between GPR54 and multiple GnRHs during these stages of development consistent with the role of GPR54 in controlling GnRH release in mammals. The increase in GPR54 and GnRH mRNAs observed during early puberty in cobia is consistent with a similar change reported in pubertal rats. This finding together with the localization of GPR54 mRNAs on GnRH neurons in fish and mammals suggests that the GPR54-GnRH interactions may be conserved in different vertebrate groups.

  16. 25 CFR 158.54 - Exchanges of restrictive lands.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Exchanges of restrictive lands. 158.54 Section 158.54 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER OSAGE LANDS § 158.54 Exchanges of restrictive lands. Upon written application of the Indians involved, the exchange of restricted...

  17. 36 CFR 7.54 - Theodore Roosevelt National Park.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Theodore Roosevelt National Park. 7.54 Section 7.54 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.54 Theodore Roosevelt National Park. (a...

  18. 36 CFR 7.54 - Theodore Roosevelt National Park.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Theodore Roosevelt National Park. 7.54 Section 7.54 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.54 Theodore Roosevelt National Park. (a...

  19. 36 CFR 7.54 - Theodore Roosevelt National Park.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Theodore Roosevelt National Park. 7.54 Section 7.54 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.54 Theodore Roosevelt National Park. (a...

  20. 36 CFR 7.54 - Theodore Roosevelt National Park.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Theodore Roosevelt National Park. 7.54 Section 7.54 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.54 Theodore Roosevelt National Park. (a...

  1. 36 CFR 7.54 - Theodore Roosevelt National Park.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Theodore Roosevelt National Park. 7.54 Section 7.54 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.54 Theodore Roosevelt National Park. (a...

  2. 46 CFR 54.05-16 - Production toughness testing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Production toughness testing. 54.05-16 Section 54.05-16... Toughness Tests § 54.05-16 Production toughness testing. (a) For vessels of welded construction, production... welding procedures shall be the same as used in the fabrication of the vessel. From each test plate, one...

  3. 34 CFR 21.54 - Review by the Secretary.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 1 2011-07-01 2011-07-01 false Review by the Secretary. 21.54 Section 21.54 Education Office of the Secretary, Department of Education EQUAL ACCESS TO JUSTICE How Are Awards Determined? § 21.54 Review by the Secretary. (a) The Secretary may decide to review— (1) An initial decision made by...

  4. 34 CFR 21.54 - Review by the Secretary.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 1 2013-07-01 2013-07-01 false Review by the Secretary. 21.54 Section 21.54 Education Office of the Secretary, Department of Education EQUAL ACCESS TO JUSTICE How Are Awards Determined? § 21.54 Review by the Secretary. (a) The Secretary may decide to review— (1) An initial decision made by...

  5. 47 CFR 54.519 - State telecommunications networks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false State telecommunications networks. 54.519 Section 54.519 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES... telecommunications networks. (a) Telecommunications services. State telecommunications networks may secure discounts...

  6. 47 CFR 54.519 - State telecommunications networks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false State telecommunications networks. 54.519 Section 54.519 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES... telecommunications networks. (a) Telecommunications services. State telecommunications networks may secure discounts...

  7. 47 CFR 54.519 - State telecommunications networks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false State telecommunications networks. 54.519 Section 54.519 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES... telecommunications networks. (a) Telecommunications services. State telecommunications networks may secure discounts...

  8. 46 CFR 54.05-5 - Toughness test specimens.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Toughness test specimens. 54.05-5 Section 54.05-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Toughness Tests § 54.05-5 Toughness test specimens. (a) Charpy V-notch impact tests. Where required, Charpy V-notch tests shall be conducted in accordanc...

  9. 46 CFR 54.05-6 - Toughness test temperatures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Toughness test temperatures. 54.05-6 Section 54.05-6... Toughness Tests § 54.05-6 Toughness test temperatures. Each toughness test must be conducted at temperatures not warmer than −20 °F or 10 °F below the minimum service temperature, whichever is lower, except that...

  10. 46 CFR 54.05-6 - Toughness test temperatures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Toughness test temperatures. 54.05-6 Section 54.05-6... Toughness Tests § 54.05-6 Toughness test temperatures. Each toughness test must be conducted at temperatures not warmer than −20 °F or 10 °F below the minimum service temperature, whichever is lower, except that...

  11. 46 CFR 54.05-6 - Toughness test temperatures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Toughness test temperatures. 54.05-6 Section 54.05-6... Toughness Tests § 54.05-6 Toughness test temperatures. Each toughness test must be conducted at temperatures not warmer than −20 °F or 10 °F below the minimum service temperature, whichever is lower, except that...

  12. 46 CFR 54.05-6 - Toughness test temperatures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Toughness test temperatures. 54.05-6 Section 54.05-6... Toughness Tests § 54.05-6 Toughness test temperatures. Each toughness test must be conducted at temperatures not warmer than −20 °F or 10 °F below the minimum service temperature, whichever is lower, except that...

  13. 26 CFR 54.4980B-4 - Qualifying events.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 17 2012-04-01 2012-04-01 false Qualifying events. 54.4980B-4 Section 54.4980B... EXCISE TAXES (CONTINUED) PENSION EXCISE TAXES § 54.4980B-4 Qualifying events. The determination of what constitutes a qualifying event is addressed in the following questions and answers: Q-1: What is a qualifying...

  14. 26 CFR 54.4980B-4 - Qualifying events.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 17 2013-04-01 2013-04-01 false Qualifying events. 54.4980B-4 Section 54.4980B... EXCISE TAXES (CONTINUED) PENSION EXCISE TAXES § 54.4980B-4 Qualifying events. The determination of what constitutes a qualifying event is addressed in the following questions and answers: Q-1: What is a qualifying...

  15. 26 CFR 54.4980B-4 - Qualifying events.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 17 2011-04-01 2011-04-01 false Qualifying events. 54.4980B-4 Section 54.4980B... EXCISE TAXES (CONTINUED) PENSION EXCISE TAXES § 54.4980B-4 Qualifying events. The determination of what constitutes a qualifying event is addressed in the following questions and answers: Q-1: What is a qualifying...

  16. 26 CFR 54.4980B-4 - Qualifying events.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 17 2014-04-01 2014-04-01 false Qualifying events. 54.4980B-4 Section 54.4980B... EXCISE TAXES (CONTINUED) PENSION EXCISE TAXES § 54.4980B-4 Qualifying events. The determination of what constitutes a qualifying event is addressed in the following questions and answers: Q-1: What is a qualifying...

  17. 26 CFR 54.7701-1 - Tax return preparer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 17 2010-04-01 2010-04-01 false Tax return preparer. 54.7701-1 Section 54.7701... EXCISE TAXES (CONTINUED) PENSION EXCISE TAXES § 54.7701-1 Tax return preparer. (a) In general. For the definition of a tax return preparer, see § 301.7701-15 of this chapter. (b) Effective/applicability date...

  18. 40 CFR 273.54 - Response to releases.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 273.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR UNIVERSAL WASTE MANAGEMENT Standards for Universal Waste Transporters § 273.54 Response to... other residues from universal wastes. (b) A universal waste transporter must determine whether any...

  19. Mechanisms of Disease: the first kiss-a crucial role for kisspeptin-1 and its receptor, G-protein-coupled receptor 54, in puberty and reproduction.

    PubMed

    Seminara, Stephanie B

    2006-06-01

    Although the hypothalamic secretion of gonadotropin-releasing hormone (GnRH) is the defining hormonal event of puberty, the physiologic mechanisms that drive secretion of GnRH at the time of sexual maturation have been difficult to identify. After puberty is initiated, the factors that modulate the frequency and amplitude of GnRH secretion in rapidly changing sex-steroid environments (i.e. the female menstrual cycle) also remain unknown. The discovery that, in both humans and mouse models, loss-of-function mutations in the gene that encodes G-protein-coupled receptor 54 result in phenotypes of hypogonadotropic hypogonadism with an absence of pubertal development has unearthed a novel pathway regulating GnRH secretion. Ligands for G-protein-coupled receptor 54 (KiSS-1R), including metastin (derived from the parent compound, kisspeptin-1) and metastin's C-terminal peptide fragments, have been shown to be powerful stimulants for GnRH release in vivo via their stimulation of G-protein-coupled receptor 54. This article reviews the discovery of the GPR54 gene, places it into the appropriate biological context, and explores the data from in vitro and in vivo studies that point to this ligand-receptor system as a major driver of GnRH secretion.

  20. 46 CFR 54.05-6 - Toughness test temperatures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Toughness test temperatures. 54.05-6 Section 54.05-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS Toughness Tests § 54.05-6 Toughness test temperatures. Each toughness test must be conducted at temperatures not warmer than −20 °F or 10 °F below the...

  1. 7 CFR 920.54 - Special purpose shipments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Special purpose shipments. 920.54 Section 920.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE KIWIFRUIT GROWN IN CALIFORNIA...

  2. 7 CFR 920.54 - Special purpose shipments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Special purpose shipments. 920.54 Section 920.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE KIWIFRUIT GROWN IN CALIFORNIA...

  3. 7 CFR 920.54 - Special purpose shipments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Special purpose shipments. 920.54 Section 920.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE KIWIFRUIT GROWN IN CALIFORNIA...

  4. 7 CFR 920.54 - Special purpose shipments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Special purpose shipments. 920.54 Section 920.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE KIWIFRUIT GROWN IN CALIFORNIA...

  5. 40 CFR 279.54 - Used oil management.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Used oil management. 279.54 Section 279.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED... the soil, groundwater, or surface water. (d) Secondary containment for existing aboveground tanks...

  6. The 5-(4-Ethynylophenoxy) isophthalic chloride

    NASA Technical Reports Server (NTRS)

    Hergenrother, P. M.; Jensen, B. J. (Inventor)

    1986-01-01

    Sulfone-ester polymers containing pendent ethynyl groups and a direct and multistep process for preparing them are disclosed. The multistep process involves the conversion of a pendent bromo group to the ethynyl group while the direct route involves reating hydroxy-terminated sulfone oligomer or polymers with a stoichiometric amount of 5-(4-ethynylphenoxy) isophthaloyl chloride. The 5-(4-ethynylphenoxy) isophthaloyl chloride and the process for preparing it are also disclosed.

  7. 41 CFR 105-54.203-2 - Active charters file.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Active charters file... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.2-Establishment of Advisory Committees § 105-54.203-2 Active... active charters. ...

  8. 41 CFR 105-54.203-2 - Active charters file.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Active charters file... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.2-Establishment of Advisory Committees § 105-54.203-2 Active... active charters. ...

  9. 41 CFR 105-54.203-2 - Active charters file.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Active charters file... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.2-Establishment of Advisory Committees § 105-54.203-2 Active... active charters. ...

  10. 41 CFR 105-54.203-2 - Active charters file.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Active charters file... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.2-Establishment of Advisory Committees § 105-54.203-2 Active... active charters. ...

  11. 27 CFR 447.54 - Administrative procedures inapplicable.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2014-04-01 2014-04-01 false Administrative procedures inapplicable. 447.54 Section 447.54 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION IMPORTATION OF ARMS, AMMUNITION AND...

  12. 27 CFR 447.54 - Administrative procedures inapplicable.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2011-04-01 2010-04-01 true Administrative procedures inapplicable. 447.54 Section 447.54 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION IMPORTATION OF ARMS, AMMUNITION AND...

  13. 27 CFR 447.54 - Administrative procedures inapplicable.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2013-04-01 2013-04-01 false Administrative procedures inapplicable. 447.54 Section 447.54 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION IMPORTATION OF ARMS, AMMUNITION AND...

  14. 27 CFR 447.54 - Administrative procedures inapplicable.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2012-04-01 2010-04-01 true Administrative procedures inapplicable. 447.54 Section 447.54 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION IMPORTATION OF ARMS, AMMUNITION AND...

  15. 28 CFR 90.54 - Allocation of funds.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Allocation of funds. 90.54 Section 90.54 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) VIOLENCE AGAINST WOMEN Indian Tribal Governments... will take into account the applicants' varying needs in addressing violence against women. ...

  16. 47 CFR 54.400 - Terms and definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Terms and definitions. 54.400 Section 54.400 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL... by the tribal governing body that members of their tribe and family members who are Indian residing...

  17. 47 CFR 54.503 - Competitive bidding requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Schools and Libraries § 54.503 Competitive bidding requirements. (a) All entities participating in the schools and libraries universal service... as provided in § 54.511(c), an eligible school, library, or consortium that includes an eligible...

  18. 32 CFR 2001.54 - Foreign government information.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Foreign government information. 2001.54 Section... Safeguarding § 2001.54 Foreign government information. The requirements described below are additional baseline safeguarding standards that may be necessary for foreign government information, other than NATO information...

  19. Pre-crisis mouse cells show strain-specific covariation in the amount of 54-kilodalton phosphoprotein and in susceptibility to transformation by simian virus 40.

    PubMed

    Chen, S; Blanck, G; Pollack, R E

    1983-09-01

    We have used several inbred mouse strains to examine the role of the 54-kilodalton (kDa) cellular phosphoprotein in transformation by the papovavirus simian virus 40. We have measured the endogenous 54-kDa phosphoprotein in cells obtained from these inbred mouse strains. To study the effect of passage, cell cultures were measured for amount of the 54-kDa phosphoprotein at the 2nd and 12th passages. In the absence of any transforming agent, the amount of endogenous 54-kDa phosphoprotein in early pre-crisis mouse cells varied in a strain-specific way. Transformation frequency varied coordinately with endogenous 54-kDa expression. Mouse strains whose cells produced a high level of endogenous 54-kDa phosphoprotein on passage did not further increase its expression after simian virus 40 transformation.

  20. 40 CFR 60.54c - Siting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Siting requirements. 60.54c Section 60.54c Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED... 15, 1997 shall prepare an analysis of the impacts of the affected facility. The analysis shall...

  1. 40 CFR 60.54c - Siting requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 6 2011-07-01 2011-07-01 false Siting requirements. 60.54c Section 60.54c Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED... 15, 1997 shall prepare an analysis of the impacts of the affected facility. The analysis shall...

  2. 28 CFR 54.305 - Preference in admission.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Preference in admission. 54.305 Section 54.305 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF... of attendance at any educational institution or other school or entity that admits as students only...

  3. 7 CFR 984.54 - Establishment of obligation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... free and reserve percentages are in effect for a marketing year, each handler shall withhold a... 7 Agriculture 8 2010-01-01 2010-01-01 false Establishment of obligation. 984.54 Section 984.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing...

  4. 7 CFR 925.54 - Special purpose shipments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Special purpose shipments. 925.54 Section 925.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... entering the channels of trade for other than the specific purposes authorized by this section. Inspection...

  5. 36 CFR 910.54 - Build-to height.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Build-to height. 910.54 Section 910.54 Parks, Forests, and Public Property PENNSYLVANIA AVENUE DEVELOPMENT CORPORATION GENERAL GUIDELINES AND UNIFORM STANDARDS FOR URBAN PLANNING AND DESIGN OF DEVELOPMENT WITHIN THE PENNSYLVANIA AVENUE...

  6. 36 CFR 910.54 - Build-to height.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Build-to height. 910.54 Section 910.54 Parks, Forests, and Public Property PENNSYLVANIA AVENUE DEVELOPMENT CORPORATION GENERAL GUIDELINES AND UNIFORM STANDARDS FOR URBAN PLANNING AND DESIGN OF DEVELOPMENT WITHIN THE PENNSYLVANIA AVENUE...

  7. 20 CFR 901.54 - Petition for reinstatement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Petition for reinstatement. 901.54 Section 901.54 Employees' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES REGULATIONS GOVERNING THE PERFORMANCE OF ACTUARIAL SERVICES UNDER THE EMPLOYEE RETIREMENT INCOME SECURITY ACT OF 1974 Suspension or...

  8. 20 CFR 901.54 - Petition for reinstatement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 4 2013-04-01 2013-04-01 false Petition for reinstatement. 901.54 Section 901.54 Employees' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES REGULATIONS GOVERNING THE PERFORMANCE OF ACTUARIAL SERVICES UNDER THE EMPLOYEE RETIREMENT INCOME SECURITY ACT OF 1974 Suspension or...

  9. 20 CFR 901.54 - Petition for reinstatement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Petition for reinstatement. 901.54 Section 901.54 Employees' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES REGULATIONS GOVERNING THE PERFORMANCE OF ACTUARIAL SERVICES UNDER THE EMPLOYEE RETIREMENT INCOME SECURITY ACT OF 1974 Suspension or...

  10. 20 CFR 901.54 - Petition for reinstatement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Petition for reinstatement. 901.54 Section 901.54 Employees' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES REGULATIONS GOVERNING THE PERFORMANCE OF ACTUARIAL SERVICES UNDER THE EMPLOYEE RETIREMENT INCOME SECURITY ACT OF 1974 Suspension or...

  11. 20 CFR 901.54 - Petition for reinstatement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Petition for reinstatement. 901.54 Section 901.54 Employees' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES REGULATIONS GOVERNING THE PERFORMANCE OF ACTUARIAL SERVICES UNDER THE EMPLOYEE RETIREMENT INCOME SECURITY ACT OF 1974 Suspension or...

  12. Expedition 54 Soyuz MS-06 Landing

    NASA Image and Video Library

    2018-02-28

    Expedition 54 crew members Alexander Misurkinat of Roscosmos, left, and NASA astronaut Mark Vande Hei are seen during a welcome ceremony at the Zhezkazgan Airport on Wednesday, Feb. 28, 2018. 2018 (February 27 Eastern time.) Vande Hei, and Misurkin returned with NASA astronaut Joe Acaba after 168 days in space where they served as members of the Expedition 53 and 54 crews onboard the International Space Station. Photo Credit: (NASA/Bill Ingalls)

  13. 28 CFR 54.120 - Transfers of property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Transfers of property. 54.120 Section 54.120 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN... property. If a recipient sells or otherwise transfers property financed in whole or in part with Federal...

  14. 27 CFR 478.54 - Change of control.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2013-04-01 2013-04-01 false Change of control. 478.54 Section 478.54 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION COMMERCE IN FIREARMS AND AMMUNITION Licenses § 478...

  15. 27 CFR 478.54 - Change of control.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2014-04-01 2014-04-01 false Change of control. 478.54 Section 478.54 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION COMMERCE IN FIREARMS AND AMMUNITION Licenses § 478...

  16. 27 CFR 478.54 - Change of control.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2012-04-01 2010-04-01 true Change of control. 478.54 Section 478.54 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION COMMERCE IN FIREARMS AND AMMUNITION Licenses § 478...

  17. 27 CFR 478.54 - Change of control.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2011-04-01 2010-04-01 true Change of control. 478.54 Section 478.54 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION COMMERCE IN FIREARMS AND AMMUNITION Licenses § 478...

  18. 7 CFR 945.54 - Minimum quantity exemption.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Minimum quantity exemption. 945.54 Section 945.54 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... regulations issued or in effect pursuant to §§ 945.40 to 945.65, inclusive, or any combination thereof. ...

  19. 40 CFR 262.54 - Special manifest requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Section 262.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Exports of Hazardous Waste § 262.54 Special... certification set forth in Item 16 of the Uniform Hazardous Waste Manifest Form: “and conforms to the terms of...

  20. 27 CFR 447.54 - Administrative procedures inapplicable.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2010-04-01 2010-04-01 false Administrative procedures inapplicable. 447.54 Section 447.54 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO... conferred under section 38, Arms Export Control Act of 1976, as amended, are excluded from the operation of...

  1. 9 CFR 54.5 - Certification by owners.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... review upon request by a State or APHIS representative all bills of sale, pedigree registration... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Certification by owners. 54.5 Section 54.5 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF...

  2. Pre-crisis mouse cells show strain-specific covariation in the amount of 54-kilodalton phosphoprotein and in susceptibility to transformation by simian virus 40.

    PubMed Central

    Chen, S; Blanck, G; Pollack, R E

    1983-01-01

    We have used several inbred mouse strains to examine the role of the 54-kilodalton (kDa) cellular phosphoprotein in transformation by the papovavirus simian virus 40. We have measured the endogenous 54-kDa phosphoprotein in cells obtained from these inbred mouse strains. To study the effect of passage, cell cultures were measured for amount of the 54-kDa phosphoprotein at the 2nd and 12th passages. In the absence of any transforming agent, the amount of endogenous 54-kDa phosphoprotein in early pre-crisis mouse cells varied in a strain-specific way. Transformation frequency varied coordinately with endogenous 54-kDa expression. Mouse strains whose cells produced a high level of endogenous 54-kDa phosphoprotein on passage did not further increase its expression after simian virus 40 transformation. Images PMID:6310588

  3. 40 CFR 414.54 - New source performance standards (NSPS).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true New source performance standards (NSPS). 414.54 Section 414.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ORGANIC CHEMICALS, PLASTICS, AND SYNTHETIC FIBERS Thermosetting Resins § 414.54 New...

  4. 40 CFR 414.54 - New source performance standards (NSPS).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 30 2013-07-01 2012-07-01 true New source performance standards (NSPS). 414.54 Section 414.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ORGANIC CHEMICALS, PLASTICS, AND SYNTHETIC FIBERS Thermosetting Resins § 414.54 New...

  5. 40 CFR 414.54 - New source performance standards (NSPS).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 30 2012-07-01 2012-07-01 false New source performance standards (NSPS). 414.54 Section 414.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ORGANIC CHEMICALS, PLASTICS, AND SYNTHETIC FIBERS Thermosetting Resins § 414.54 New...

  6. 40 CFR 414.54 - New source performance standards (NSPS).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 29 2011-07-01 2009-07-01 true New source performance standards (NSPS). 414.54 Section 414.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ORGANIC CHEMICALS, PLASTICS, AND SYNTHETIC FIBERS Thermosetting Resins § 414.54 New...

  7. 40 CFR 414.54 - New source performance standards (NSPS).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 29 2014-07-01 2012-07-01 true New source performance standards (NSPS). 414.54 Section 414.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ORGANIC CHEMICALS, PLASTICS, AND SYNTHETIC FIBERS Thermosetting Resins § 414.54 New...

  8. 9 CFR 54.5 - Certification by owners.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Certification by owners. 54.5 Section 54.5 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... certificates, and other records regarding movement of animals into and from the flock; (b) If the owner...

  9. 9 CFR 54.5 - Certification by owners.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Certification by owners. 54.5 Section 54.5 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... certificates, and other records regarding movement of animals into and from the flock; (b) If the owner...

  10. 9 CFR 54.5 - Certification by owners.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Certification by owners. 54.5 Section 54.5 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... certificates, and other records regarding movement of animals into and from the flock; (b) If the owner...

  11. 9 CFR 54.5 - Certification by owners.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Certification by owners. 54.5 Section 54.5 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... certificates, and other records regarding movement of animals into and from the flock; (b) If the owner...

  12. 29 CFR 2200.54 - Requests for admissions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 9 2011-07-01 2011-07-01 false Requests for admissions. 2200.54 Section 2200.54 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH REVIEW COMMISSION RULES OF PROCEDURE... complexity of the case or the number of citation items necessitates a greater number of requested admissions...

  13. 46 CFR 111.54-1 - Circuit breakers.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Circuit breakers. 111.54-1 Section 111.54-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL... breaker must not: (1) Be dependent upon mechanical cooling to operate within its rating; or (2) Have a...

  14. 46 CFR 111.54-1 - Circuit breakers.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Circuit breakers. 111.54-1 Section 111.54-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL... breaker must not: (1) Be dependent upon mechanical cooling to operate within its rating; or (2) Have a...

  15. 46 CFR 111.54-1 - Circuit breakers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Circuit breakers. 111.54-1 Section 111.54-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL... breaker must not: (1) Be dependent upon mechanical cooling to operate within its rating; or (2) Have a...

  16. 46 CFR 111.54-1 - Circuit breakers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Circuit breakers. 111.54-1 Section 111.54-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL... breaker must not: (1) Be dependent upon mechanical cooling to operate within its rating; or (2) Have a...

  17. 9 CFR 54.10 - Tests for scrapie.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Tests for scrapie. 54.10 Section 54.10 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... of scrapie conducted on live or dead animals for use in the Scrapie Eradication Program. The...

  18. 9 CFR 54.10 - Tests for scrapie.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Tests for scrapie. 54.10 Section 54.10 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... of scrapie conducted on live or dead animals for use in the Scrapie Eradication Program. The...

  19. 9 CFR 54.10 - Tests for scrapie.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Tests for scrapie. 54.10 Section 54.10 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... of scrapie conducted on live or dead animals for use in the Scrapie Eradication Program. The...

  20. 9 CFR 54.10 - Tests for scrapie.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Tests for scrapie. 54.10 Section 54.10 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... of scrapie conducted on live or dead animals for use in the Scrapie Eradication Program. The...

  1. 9 CFR 54.10 - Tests for scrapie.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Tests for scrapie. 54.10 Section 54.10 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... of scrapie conducted on live or dead animals for use in the Scrapie Eradication Program. The...

  2. Expedition 54 Soyuz MS-06 Landing

    NASA Image and Video Library

    2018-02-28

    Girls in ceremonial Kazak dress wait to welcome the return of Expedition 54 crew members Joe Acaba and Mark Vande Hei of NASA and cosmonaut Alexander Misurkin at a Zhezkazgan Airport welcome ceremony in Kazakhstan on Wednesday, Feb. 28, 2018. 2018 (February 27 Eastern time.) Acaba, Vande Hei, and Misurkin are returning after 168 days in space where they served as members of the Expedition 53 and 54 crews onboard the International Space Station. Photo Credit: (NASA/Bill Ingalls)

  3. Expedition 54 Soyuz MS-06 Landing

    NASA Image and Video Library

    2018-02-28

    Expedition 54 crew members Joe Acaba and Mark Vande Hei of NASA and cosmonaut Alexander Misurkin are seen inside their Soyuz MS-06 spacecraft shortly after they landed near the town of Zhezkazgan, Kazakhstan on Wednesday, Feb. 28, 2018 (February 27 Eastern time.) Acaba, Vande Hei, and Misurkin are returning after 168 days in space where they served as members of the Expedition 53 and 54 crews onboard the International Space Station. Photo Credit: (NASA/Bill Ingalls)

  4. 10 CFR 54.13 - Completeness and accuracy of information.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Completeness and accuracy of information. 54.13 Section 54.13 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REQUIREMENTS FOR RENEWAL OF OPERATING LICENSES FOR NUCLEAR POWER PLANTS General Provisions § 54.13 Completeness and accuracy of information. (a...

  5. 10 CFR 54.13 - Completeness and accuracy of information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Completeness and accuracy of information. 54.13 Section 54.13 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REQUIREMENTS FOR RENEWAL OF OPERATING LICENSES FOR NUCLEAR POWER PLANTS General Provisions § 54.13 Completeness and accuracy of information. (a...

  6. 10 CFR 54.13 - Completeness and accuracy of information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Completeness and accuracy of information. 54.13 Section 54.13 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REQUIREMENTS FOR RENEWAL OF OPERATING LICENSES FOR NUCLEAR POWER PLANTS General Provisions § 54.13 Completeness and accuracy of information. (a...

  7. 10 CFR 54.13 - Completeness and accuracy of information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Completeness and accuracy of information. 54.13 Section 54.13 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REQUIREMENTS FOR RENEWAL OF OPERATING LICENSES FOR NUCLEAR POWER PLANTS General Provisions § 54.13 Completeness and accuracy of information. (a...

  8. 10 CFR 54.13 - Completeness and accuracy of information.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Completeness and accuracy of information. 54.13 Section 54.13 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REQUIREMENTS FOR RENEWAL OF OPERATING LICENSES FOR NUCLEAR POWER PLANTS General Provisions § 54.13 Completeness and accuracy of information. (a...

  9. 36 CFR 5.4 - Commercial passenger-carrying motor vehicles.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... motor vehicles. 5.4 Section 5.4 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR COMMERCIAL AND PRIVATE OPERATIONS § 5.4 Commercial passenger-carrying motor vehicles. (a) The commercial transportation of passengers by motor vehicles except as authorized under a contract or...

  10. 21 CFR 1315.54 - Waiver or modification of rules.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Waiver or modification of rules. 1315.54 Section 1315.54 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Hearings § 1315.54 Waiver or...

  11. 21 CFR 1315.54 - Waiver or modification of rules.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Waiver or modification of rules. 1315.54 Section 1315.54 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Hearings § 1315.54 Waiver or...

  12. 21 CFR 1315.54 - Waiver or modification of rules.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Waiver or modification of rules. 1315.54 Section 1315.54 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Hearings § 1315.54 Waiver or...

  13. 21 CFR 1315.54 - Waiver or modification of rules.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Waiver or modification of rules. 1315.54 Section 1315.54 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Hearings § 1315.54 Waiver or...

  14. 21 CFR 1315.54 - Waiver or modification of rules.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Waiver or modification of rules. 1315.54 Section 1315.54 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Hearings § 1315.54 Waiver or...

  15. 42 CFR 54a.7 - Nondiscrimination requirement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Nondiscrimination requirement. 54a.7 Section 54a.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE... religion, a religious belief, a refusal to hold a religious belief, or a refusal to actively participate in...

  16. 42 CFR 54a.7 - Nondiscrimination requirement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Nondiscrimination requirement. 54a.7 Section 54a.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE... religion, a religious belief, a refusal to hold a religious belief, or a refusal to actively participate in...

  17. 42 CFR 54a.7 - Nondiscrimination requirement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Nondiscrimination requirement. 54a.7 Section 54a.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE... religion, a religious belief, a refusal to hold a religious belief, or a refusal to actively participate in...

  18. 42 CFR 54a.7 - Nondiscrimination requirement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Nondiscrimination requirement. 54a.7 Section 54a.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE... religion, a religious belief, a refusal to hold a religious belief, or a refusal to actively participate in...

  19. 42 CFR 54a.7 - Nondiscrimination requirement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Nondiscrimination requirement. 54a.7 Section 54a.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS CHARITABLE CHOICE... religion, a religious belief, a refusal to hold a religious belief, or a refusal to actively participate in...

  20. 22 CFR 42.54 - Order of consideration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Order of consideration. 42.54 Section 42.54 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND...(b) in order to apply formally for a visa as follows: (1) In the chronological order of the priority...

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