Science.gov

Sample records for provisional process specifications

  1. A provisional regulatory gene network for specification of endomesoderm in the sea urchin embryo

    NASA Technical Reports Server (NTRS)

    Davidson, Eric H.; Rast, Jonathan P.; Oliveri, Paola; Ransick, Andrew; Calestani, Cristina; Yuh, Chiou-Hwa; Minokawa, Takuya; Amore, Gabriele; Hinman, Veronica; Arenas-Mena, Cesar; Otim, Ochan; Brown, C. Titus; Livi, Carolina B.; Lee, Pei Yun; Revilla, Roger; Schilstra, Maria J.; Clarke, Peter J C.; Rust, Alistair G.; Pan, Zhengjun; Arnone, Maria I.; Rowen, Lee; Cameron, R. Andrew; McClay, David R.; Hood, Leroy; Bolouri, Hamid

    2002-01-01

    We present the current form of a provisional DNA sequence-based regulatory gene network that explains in outline how endomesodermal specification in the sea urchin embryo is controlled. The model of the network is in a continuous process of revision and growth as new genes are added and new experimental results become available; see http://www.its.caltech.edu/mirsky/endomeso.htm (End-mes Gene Network Update) for the latest version. The network contains over 40 genes at present, many newly uncovered in the course of this work, and most encoding DNA-binding transcriptional regulatory factors. The architecture of the network was approached initially by construction of a logic model that integrated the extensive experimental evidence now available on endomesoderm specification. The internal linkages between genes in the network have been determined functionally, by measurement of the effects of regulatory perturbations on the expression of all relevant genes in the network. Five kinds of perturbation have been applied: (1) use of morpholino antisense oligonucleotides targeted to many of the key regulatory genes in the network; (2) transformation of other regulatory factors into dominant repressors by construction of Engrailed repressor domain fusions; (3) ectopic expression of given regulatory factors, from genetic expression constructs and from injected mRNAs; (4) blockade of the beta-catenin/Tcf pathway by introduction of mRNA encoding the intracellular domain of cadherin; and (5) blockade of the Notch signaling pathway by introduction of mRNA encoding the extracellular domain of the Notch receptor. The network model predicts the cis-regulatory inputs that link each gene into the network. Therefore, its architecture is testable by cis-regulatory analysis. Strongylocentrotus purpuratus and Lytechinus variegatus genomic BAC recombinants that include a large number of the genes in the network have been sequenced and annotated. Tests of the cis-regulatory predictions of

  2. Association Between Specific Depression Symptoms and Glycemic Control Among Patients With Comorbid Type 2 Diabetes and Provisional Depression

    PubMed Central

    Czech, Stephanie J.; Orsillo, Susan M.; Pirraglia, Paul A.; English, Thomas M.; Connell, Alexa J.

    2015-01-01

    Objective: To determine whether specific depression symptoms are associated with glycemic control independent of potential demographic and clinical covariates among primary care patients with comorbid type 2 diabetes and provisional threshold or subthreshold depression. Method: We examined a convenience sample of patients diagnosed with type 2 diabetes and provisional threshold or subthreshold depression (N = 82) at 2 family health centers. Cases were identified using a population-based registry of patients diagnosed with type 2 diabetes (ICD-9 codes 250.00 for controlled type 2 diabetes and 250.02 for uncontrolled type 2 diabetes). Data from patients with a primary care provider appointment from the beginning of April 2011 through the end of June 2012 and with at least one 9-item Patient Health Questionnaire (PHQ-9) depression screener and a glycated hemoglobin A1c (HbA1c) laboratory test between 2 weeks before and 10 weeks after PHQ-9 screening were eligible for inclusion. We defined provisional threshold or subthreshold depression using PHQ-9 scoring criteria, which were designed to yield provisional diagnostic information about major depressive disorder based on DSM-5 diagnostic criteria. Results: Patients reporting higher severity of sleep problems on the PHQ-9 had significantly higher HbA1c levels (mean = 8.48, SD = 2.17) compared to patients reporting lower severity or absence of this symptom (mean = 7.19, SD = 1.34, t48.88 = −3.13, P = .003). Problems with sleep contributed unique variance on glycemic control (β = 0.27, P = .02) when controlling for potential clinical and demographic covariates, with those reporting more sleep difficulties having higher HbA1c levels. Conclusions: For patients with type 2 diabetes and provisional threshold or subthreshold depression, it may be prudent to aggressively address sleep problems as a potential mechanism toward improving diabetes control. PMID:26835160

  3. Provisional License.

    ERIC Educational Resources Information Center

    Preusser, David F.; Leaf, William A.

    2003-01-01

    Describes the phase in a graduated driver-licensing system that includes the provisional license, which allows young people to drive under certain restrictions. Discusses how the licensing system has emerged as an important factor in reducing crash rates among teenage drivers. (Contains 1 table, 2 figures, and 18 references.) (WFA)

  4. 21 CFR 81.1 - Provisional lists of color additives.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Provisional lists of color additives. 81.1 Section 81.1 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL GENERAL SPECIFICATIONS AND GENERAL RESTRICTIONS FOR PROVISIONAL COLOR ADDITIVES FOR USE IN FOODS, DRUGS, AND COSMETICS § 81.1 Provisional lists...

  5. Generalized provisional seed zones for native plants.

    PubMed

    Bower, Andrew D; St Clair, J Bradley; Erickson, Vicky

    2014-07-01

    Deploying well-adapted and ecologically appropriate plant materials is a core component of successful restoration projects. We have developed generalized provisional seed zones that can be applied to any plant species in the United States to help guide seed movement. These seed zones are based on the intersection of high-resolution climatic data for winter minimum temperature and aridity (as measured by annual heat : moisture index), each classified into discrete bands. This results in the delineation of 64 provisional seed zones for the continental United States. These zones represent areas of relative climatic similarity, and movement of seed within these zones should help to minimize maladaptation. Superimposing Omernik's level III ecoregions over these seed zones distinguishes areas that are similar climatically yet different ecologically. A quantitative comparison of provisional seed zones with level III ecoregions and provisional seed zones within ecoregions for three species showed that provisional seed zone within ecoregion often explained the greatest proportion of variation in a suite of traits potentially related to plant fitness. These provisional seed zones can be considered a starting point for guidelines for seed transfer, and should be utilized in conjunction with appropriate species-specific information as well as local knowledge of microsite differences. PMID:25154085

  6. Enhanced aesthetics using provisionalization.

    PubMed

    Braun, J M

    1996-01-01

    The proper fabrication of provisional restorations is integral to the overall success of restorative dentistry, as these templates are the initial architecture for the completed case. In a clinical setting, restorations may be utilized for an extended period, during which time the clinician and patient must feel confident. Due partially to a new generation of dental materials with unique properties, provisionalization can be predictably achieved. This article reviews the clinical criteria for the fabrication of interim restorations using a light cure/dual phase temporary crown and bridge material (Provipont DC, Ivoclar Vivadent, Amherst, NY) and its effect on the overall success of restorative procedures, including anterior and posterior restorations. PMID:9227154

  7. Guided implant surgery with placement of a presurgical CAD/CAM patient-specific abutment and provisional in the esthetic zone.

    PubMed

    Mandelaris, George A; Vlk, Scott D

    2014-01-01

    Parallel use of implant treatment planning software and cone-beam computed tomography (CBCT) can, using certain criteria, consolidate steps and streamline tooth replacement strategies. The authors describe such a case in the esthetic zone whereby flapless extraction and immediate implant placement using CT-guided surgery were performed simultaneously, with placement of a computer-aided design/computer-aided manufactured (CAD/CAM) patient-specific abutment and non-occlusal function provisional in a single visit (supporting the "one-abutment, one-time" concept). An over-retained primary cuspid in a periodontally healthy woman with well-controlled type-2 diabetes was replaced with an implant and CAD/CAM patient-specific abutment in the No. 11 position. A necessary implant-axis angle correction was customized using digital information from a CBCT scan and implant treatment planning software, without the need for site development or a conventional impression. This data integration and streamlined workflow enabled fabrication of a CAD/CAM patient-specific abutment before surgical treatment. The abutment remained in place from implant surgery to the prosthetic phase, with minimal soft-tissue changes, enabling preservation of pink esthetics and expediting treatment. The result was a preserved emergence profile in the presence of high esthetic demands. However, due to slight post-extraction soft-tissue changes, digital reformatting of the abutment was required when the final crown was fabricated, thus limiting the disruption of the biologic width to a one-time occurrence. The importance of case selection for this treatment protocol in the esthetic zone cannot be overemphasized. A thick crestal dentoalveolar bone phenotype (> 1 mm, approaching 2 mm in this case), broad zone of attached and keratinized gingiva (3 mm to 4 mm in this case), adequate peri-implant soft-tissue thickness (> 1 mm in this case), and high primary implant stability (ISQ = 80 in this case) were all

  8. Development of a Provisional Domain Model for the Nursing Process for Use within the Health Level 7 Reference Information Model

    PubMed Central

    Goossen, William T.F.; Ozbolt, Judy G.; Coenen, Amy; Park, Hyeoun-Ae; Mead, Charles; Ehnfors, Margareta; Marin, Heimar F.

    2004-01-01

    Objective: Since 1999, the Nursing Terminology Summits have promoted the development, evaluation, and use of reference terminology for nursing and its integration into comprehensive health care data standards. The use of such standards to represent nursing knowledge, terminology, processes, and information in electronic health records will enhance continuity of care, decision support, and the exchange of comparable patient information. As part of this activity, working groups at the 2001, 2002, and 2003 Summit Conferences examined how to represent nursing information in the Health Level 7 (HL7) Reference Information Model (RIM). Design: The working groups represented the nursing process as a dynamic sequence of phases, each containing information specific to the activities of the phase. They used Universal Modeling Language (UML) to represent this domain knowledge in models. An Activity Diagram was used to create a dynamic model of the nursing process. After creating a structural model of the information used at each stage of the nursing process, the working groups mapped that information to the HL7 RIM. They used a hierarchical structure for the organization of nursing knowledge as the basis for a hierarchical model for “Findings about the patient.” The modeling and mapping reported here were exploratory and preliminary, not exhaustive or definitive. The intent was to evaluate the feasibility of representing some types of nursing information consistently with HL7 standards. Measurements: The working groups conducted a small-scale validation by testing examples of nursing terminology against the HL7 RIM class “Observation.” Results: It was feasible to map patient information from the proposed models to the RIM class “Observation.” Examples illustrate the models and the mapping of nursing terminology to the HL7 RIM. Conclusion: It is possible to model and map nursing information into the comprehensive health care information model, the HL7 RIM. These

  9. Increasing Immunization Compliance by Reducing Provisional Admittance

    ERIC Educational Resources Information Center

    Davis, Wendy S.; Varni, Susan E.; Barry, Sara E.; Frankowski, Barbara L.; Harder, Valerie S.

    2016-01-01

    Students in Vermont with incomplete or undocumented immunization status are provisionally admitted to schools and historically had a calendar year to resolve their immunization status. The process of resolving these students' immunization status was challenging for school nurses. We conducted a school-based quality improvement effort to increase…

  10. INTERACTIVE NAME PLACEMENT FOR PROVISIONAL MAPS.

    USGS Publications Warehouse

    Goldberg, Jeffrey L.; Miller, Thomas C.

    1983-01-01

    Computer generation and placement of map type has been refined into a production mode at Mid-Continent Mapping Center (MCMC) for USGS 1:24,000- and 1:25,000-scale Provisional maps. The map collar program is written in FORTRAN using batch processing that allows the program to work in the background.

  11. Provisional Teacher Program: Implementation Guidelines.

    ERIC Educational Resources Information Center

    New Jersey State Dept. of Education, Trenton.

    These guidelines are offered to public school districts and nonpublic schools to assist in implementing the provisional certification requirements for first year teachers in New Jersey. The guidelines address: (1) membership of the Professional Support Team that provides the training, support, and supervision for provisional teachers; (2) roles…

  12. Increasing Immunization Compliance by Reducing Provisional Admittance.

    PubMed

    Davis, Wendy S; Varni, Susan E; Barry, Sara E; Frankowski, Barbara L; Harder, Valerie S

    2016-08-01

    Students in Vermont with incomplete or undocumented immunization status are provisionally admitted to schools and historically had a calendar year to resolve their immunization status. The process of resolving these students' immunization status was challenging for school nurses. We conducted a school-based quality improvement effort to increase student compliance with Vermont immunization regulations using a collaborative learning approach with public health school liaisons and school nurses from public schools to reduce provisional admittance in 2011-2012. Strategies included using a tracking system, accessing the immunization registry, promoting immunization importance, tracking immunization plans, and working with medical homes to update records. Participating school nurses observed decreases in the number of provisionally admitted students, although this reduction was not significantly different than matched comparison schools. We also found the number of provisionally admitted students fluctuated throughout the year and resolving the immunization status of New Americans and exchange students required special attention. Our approach supports the coordinated school health model and demonstrates the critical role school nurses play in improving population health outcomes. PMID:26699951

  13. Sequential provisional implant prosthodontics therapy.

    PubMed

    Zinner, Ira D; Markovits, Stanley; Jansen, Curtis E; Reid, Patrick E; Schnader, Yale E; Shapiro, Herbert J

    2012-01-01

    The fabrication and long-term use of first- and second-stage provisional implant prostheses is critical to create a favorable prognosis for function and esthetics of a fixed-implant supported prosthesis. The fixed metal and acrylic resin cemented first-stage prosthesis, as reviewed in Part I, is needed for prevention of adjacent and opposing tooth movement, pressure on the implant site as well as protection to avoid micromovement of the freshly placed implant body. The second-stage prosthesis, reviewed in Part II, should be used following implant uncovering and abutment installation. The patient wears this provisional prosthesis until maturation of the bone and healing of soft tissues. The second-stage provisional prosthesis is also a fail-safe mechanism for possible early implant failures and also can be used with late failures and/or for the necessity to repair the definitive prosthesis. In addition, the screw-retained provisional prosthesis is used if and when an implant requires removal or other implants are to be placed as in a sequential approach. The creation and use of both first- and second-stage provisional prostheses involve a restorative dentist, dental technician, surgeon, and patient to work as a team. If the dentist alone cannot do diagnosis and treatment planning, surgery, and laboratory techniques, he or she needs help by employing the expertise of a surgeon and a laboratory technician. This team approach is essential for optimum results. PMID:23220306

  14. Surface integrity of provisional resin materials

    NASA Astrophysics Data System (ADS)

    Abouelatta, O. B.; El-Bediwi, A.; Sakrana, A.; Jiang, X. Q.; Blunt, L.

    2006-03-01

    Provisional resin materials are widely used in prosthetic dentistry and play an important role in the success of restorative treatment. Therefore, these materials must meet the requirements of preserving surface integrity during the treatment process. This study was done to evaluate surface roughness and microhardness of two provisional resin materials after 37 °C water storage. Two rectangular samples 21 mm × 11 mm × 3 mm, one bis-acrylic (bis-acrylic-Protemp II) and one polyethyl methacrylate (Trim®-PEMA) were fabricated as examples of provisional materials (n = 5 per material). The specimens were stored in 37 °C deionized distilled water for 24 h, 1, 2 and 3 weeks. The control specimens were not stored in water. The surface roughness of the tested materials (n = 10) was measured using a profilometer. Microhardness tests were conducted using a Vickers microscope mounted indenter system (n = 10). At 24 h, the surface roughness was recorded with bis-acrylic-Protemp II as higher than methacrylate materials. No significant differences of microhardness between Trim®-PEMA and bis-acrylic-Protemp II were recognized at 1, 2 and 3 weeks. The microhardness values increased with the increase of surface roughness and vice versa in both Trim®-PEMA and bis-acrylic-Protemp II. Both surface roughness and microhardness are affected by water storage. Bis-acrylic-Protemp II revealed better results in hardness than methacrylate resins, whereas Trim®-PEMA has a better surface roughness.

  15. Provisionalization: the key to cosmetic & restorative success.

    PubMed

    Rossein, K

    1995-07-01

    This article demonstrates the importance of provisionals in achieving success with the final restoration. The purposes of a provisional restoration are discussed as well as the various types of provisional materials that are available. A direct technique, using a clear plastic matrix for the fabrication of a provisional bridge, is described. Included is a procedure for forming a pontic that will have accurate contacts and proper contours and embrasures every time. PMID:8595589

  16. Provisional Admission Practices: Blending Access and Support to Facilitate Student Success

    ERIC Educational Resources Information Center

    Nichols, Andrew Howard; Clinedinst, Melissa

    2013-01-01

    This report examines provisional admission as an initiative that can expand four-year college access and success for students from economically disadvantaged backgrounds. Provisional admission policies and programs enable students to enroll at an institution under specific conditions. Students are often required to meet certain academic…

  17. Discoloration of Provisional Restorations after Oral Rinses

    PubMed Central

    Turgut, Sedanur; Bagis, Bora; Ayaz, Elif Aydogan; Ulusoy, Kıvanç Utku; Altintas, Subutay Han; Korkmaz, Fatih Mehmet; Bagis, Nilsun

    2013-01-01

    significant (p <0.05). A* values were found to be significantly higher with oral rinses (p<0.05), except Protemp II immersed in benzydamine HCl or alcohol-containing mouthwash. Conclusions: The type of the oral rinse did not affect the discoloration process. For long-term esthetic results, choosing MMA-based materials for provisional restorations appears to be more effective. PMID:24046524

  18. Mechanical behavior of provisional implant prosthetic abutments

    PubMed Central

    Serra-Pastor, Blanca; Roig-Vanaclocha, Ana; Román-Rodriguez, Juan-Luis; Fons-Font, Antonio

    2015-01-01

    Introduction: Implant-supported prostheses have to overcome a major difficulty presented by the morphology and esthetics of peri-implant tissues in the anterior sector. Diverse therapeutic techniques are used for managing the mucosa adjacent to the implant and the most noteworthy is immediate/deferred fixed provisionalization. Objectives: In vitro testing of strength and deformation of implant prosthetic abutments made from different materials (Titanium/PEEK/methacrylate). Material and Methods: Forty Sweden&Martina® implant prosthetic abutments (n=40) were divided into five groups: Group MP: methacrylate provisional abutments with machined titanium base; Group PP: Poly ether ether ketone (PEEK) provisional abutments; Group TP: titanium provisional abutments; Group TAD: titanium anti-rotational definitive abutments; Group TRD: titanium rotational definitive abutments. Their mechanical behavior under static loading was analyzed. Samples were examined under a microscope to determine the type of fracture produced. Results and Conclusions: Definitive anti-rotational titanium abutments and definitive rotational titanium abutments achieved the best mean compression strength, while PEEK resin provisional abutments obtained the lowest. The group that showed the greatest elastic deformation was the group of titanium provisional abutments. Key words:Immediate loading, immediate provisionalization, implant prosthetic abutment, definitive implant prosthetic abutment. PMID:25129253

  19. Comparison of provisional with final notifiable disease case counts - National Notifiable Diseases Surveillance System, 2009.

    PubMed

    2013-09-13

    States report notifiable disease cases to CDC through the National Notifiable Diseases Surveillance System (NNDSS). This allows CDC to assist with public health action and monitor infectious diseases across jurisdictional boundaries nationwide. The Morbidity and Mortality Weekly Report (MMWR) is used to disseminate these data on infectious disease incidence. The extent to which the weekly notifiable conditions are overreported or underreported can affect public health understanding of changes in the burden, distribution, and trends in disease, which is essential for control of communicable diseases. NNDSS encourages state health departments to notify CDC of a case when initially reported. These cases are included in the weekly provisional counts. The status of reported cases can change after further investigation by the states, resulting in differences between provisional and final counts. Increased knowledge of these differences can help in guiding the use of information from NNDSS. To quantify the extent to which final counts differ from provisional counts of notifiable infectious disease in the United States, CDC analyzed 2009 NNDSS data for 67 conditions. The results of this analysis demonstrate that for five conditions, final case counts were lower than provisional counts, but for 59 conditions, final counts were higher than provisional counts. The median difference between final and provisional counts was 16.7%; differences were ≤20% for 39 diseases but >50% for 12. These differences occur for various diseases and in all states. Provisional case counts should be interpreted with caution and an understanding of the reporting process. PMID:24025757

  20. 49 CFR 385.115 - Reapplying for provisional registration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Reapplying for provisional registration. 385.115... provisional registration. (a) A Mexico-domiciled motor carrier whose provisional operating authority or provisional Certificate of Registration has been revoked may reapply under part 365 or 368 of this...

  1. 49 CFR 385.115 - Reapplying for provisional registration.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 5 2011-10-01 2011-10-01 false Reapplying for provisional registration. 385.115... provisional registration. (a) A Mexico-domiciled motor carrier whose provisional operating authority or provisional Certificate of Registration has been revoked may reapply under part 365 or 368 of this...

  2. Role of provisional restorations in endodontic therapy

    PubMed Central

    Sivakumar, Jambai Sampathkumar; Suresh Kumar, Beri Narasimiah; Shyamala, Palaniyandi Vadivel

    2013-01-01

    Root-canal treatment can be carried out in single visit in vital, non-infected teeth, eliminating the need for dressing and provisionalization. Many clinical cases with infected canals require dressing with antibacterial medicaments in a multivisit treatment in which effective provisionalization for different periods of time becomes mandatory. Successful root-canal treatment requires effective mechanical and chemical debridement, elimination of bacteria and pulp tissue remnants and proper canal shaping to facilitate effective obturation. Lack of satisfactory temporary restorations during endodontic therapy ranked second amongst the contributing factors in continuing pain after the commencement of treatment. This review aims to provide an overview of the materials used for provisionalization during and immediately after endodontic treatment. PMID:23946564

  3. Process Specification for Eddy Current Inspection

    NASA Technical Reports Server (NTRS)

    Koshti, Ajay

    2011-01-01

    This process specification establishes the minimum requirements for eddy current inspection of flat surfaces, fastener holes, threaded fasteners and seamless and welded tubular products made from nonmagnetic alloys such as aluminum and stainless steel.

  4. 14 CFR 121.207 - Provisionally certificated airplanes: Operating limitations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Provisionally certificated airplanes... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Airplane Performance Operating Limitations § 121.207 Provisionally certificated airplanes: Operating limitations....

  5. 14 CFR 121.207 - Provisionally certificated airplanes: Operating limitations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Provisionally certificated airplanes... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Airplane Performance Operating Limitations § 121.207 Provisionally certificated airplanes: Operating limitations....

  6. 14 CFR 121.207 - Provisionally certificated airplanes: Operating limitations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Provisionally certificated airplanes... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Airplane Performance Operating Limitations § 121.207 Provisionally certificated airplanes: Operating limitations....

  7. 14 CFR 121.207 - Provisionally certificated airplanes: Operating limitations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Provisionally certificated airplanes... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Airplane Performance Operating Limitations § 121.207 Provisionally certificated airplanes: Operating limitations....

  8. 14 CFR 121.207 - Provisionally certificated airplanes: Operating limitations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Provisionally certificated airplanes... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Airplane Performance Operating Limitations § 121.207 Provisionally certificated airplanes: Operating limitations....

  9. 14 CFR 141.7 - Provisional pilot school certificate.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Provisional pilot school certificate. 141.7... (CONTINUED) SCHOOLS AND OTHER CERTIFICATED AGENCIES PILOT SCHOOLS General § 141.7 Provisional pilot school... provisional pilot school certificate with ratings....

  10. 14 CFR 141.7 - Provisional pilot school certificate.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Provisional pilot school certificate. 141.7... (CONTINUED) SCHOOLS AND OTHER CERTIFICATED AGENCIES PILOT SCHOOLS General § 141.7 Provisional pilot school... provisional pilot school certificate with ratings....

  11. 48 CFR 232.102-70 - Provisional delivery payments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Provisional delivery... Item Purchase Financing 232.102-70 Provisional delivery payments. (a) The contracting officer may establish provisional delivery payments to pay contractors for the costs of supplies and services...

  12. Mechanical properties of four methylmethacrylate-based resins for provisional fixed restorations.

    PubMed

    Hernandez, E P; Oshida, Y; Platt, J A; Andres, C J; Barco, M T; Brown, D T

    2004-01-01

    The use of a provisional restoration is an important phase in the treatment of the dental prosthetic patient. A good provisional restoration should satisfy the following requirements: pulpal protection, positional stability, ease in cleaning, accurate margins, wear resistance, dimensional stability, and serve as a diagnostic aid in treatment assessment and esthetics. There is a tendency for discoloration, occlusal wear, and fracture that eventually leads to unnecessary repair. Heat-processed and reinforced methacrylate-based resins have been used to improve the mechanical and physical properties of provisional restorations. Among various improvements, the interpenetrating network crosslinked PMMA (IPN) has been shown to have superior mechanical properties if manufactured through a dough compression molding process at 130 degrees C. However, there have been no published data that relate with the use of this material for fixed provisional restorations. The objective of this study was to compare four methyl methacrylate-based resins for provisional crowns and bridges with varying processing cycles, including JET [self-cure], ACRALON [heat-cured], titanium dioxide filled PMMA [heat-cured], and IPN [heat-cured denture tooth resin]. Properties studied included transverse strength, toughness, rigidity, and hardness. From the results of this study the following conclusions can be made: the IPN group may have had a lower degree of conversion as demonstrated by decreased strength, toughness, and hardness data as compared with Acralon. Increasing the polymerization cycle of unmodified Acralon resin causes a significant increase in strength. PMID:14757958

  13. Evaluation of resins for provisional restorations.

    PubMed

    Burgess, J O; Haveman, C W; Butzin, C

    1992-06-01

    An in vivo study of two resin materials (Barricaid and Caulk Temporary Crown and Bridge Resin) was done to determine the retention, post-operative sensitivity, and fabrication time of provisional restorations made from these materials. Following the placement of these resins in 67 intracoronal cavity preparations of 19 adult patients, a baseline evaluation was made which included a clinical examination and color slides. Twenty-four hours after the temporary restorations were placed, the patients completed evaluations of the post-operative sensitivity experienced. There was no difference in post-operative sensitivity between the teeth restored with Barricaid or Caulk Temporary Crown and Bridge Resin. At the insertion appointment of the final restoration, the interim restoration's success rate was determined. There was no difference between the retention of the two provisional materials. Fabrication time was significantly different with Barricaid restorations requiring less than one-half the fabrication time of the Caulk Temporary Crown and Bridge Resin material. PMID:1388950

  14. EUV mask process specifics and development challenges

    NASA Astrophysics Data System (ADS)

    Nesladek, Pavel

    2014-07-01

    EUV lithography is currently the favorite and most promising candidate among the next generation lithography (NGL) technologies. Decade ago the NGL was supposed to be used for 45 nm technology node. Due to introduction of immersion 193nm lithography, double/triple patterning and further techniques, the 193 nm lithography capabilities was greatly improved, so it is expected to be used successfully depending on business decision of the end user down to 10 nm logic. Subsequent technology node will require EUV or DSA alternative technology. Manufacturing and especially process development for EUV technology requires significant number of unique processes, in several cases performed at dedicated tools. Currently several of these tools as e.g. EUV AIMS or actinic reflectometer are not available on site yet. The process development is done using external services /tools with impact on the single unit process development timeline and the uncertainty of the process performance estimation, therefore compromises in process development, caused by assumption about similarities between optical and EUV mask made in experiment planning and omitting of tests are further reasons for challenges to unit process development. Increased defect risk and uncertainty in process qualification are just two examples, which can impact mask quality / process development. The aim of this paper is to identify critical aspects of the EUV mask manufacturing with respect to defects on the mask with focus on mask cleaning and defect repair and discuss the impact of the EUV specific requirements on the experiments needed.

  15. Ribosomopathies: Global process, tissue specific defects.

    PubMed

    Yelick, Pamela C; Trainor, Paul A

    2015-01-01

    Disruptions in ribosomal biogenesis would be expected to have global and in fact lethal effects on a developing organism. However, mutations in ribosomal protein genes have been shown in to exhibit tissue specific defects. This seemingly contradictory finding - that globally expressed genes thought to play fundamental housekeeping functions can in fact exhibit tissue and cell type specific functions - provides new insight into roles for ribosomes, the protein translational machinery of the cell, in regulating normal development and disease. Furthermore it illustrates the surprisingly dynamic nature of processes regulating cell type specific protein translation. In this review, we discuss our current knowledge of a variety of ribosomal protein mutations associated with human disease, and models to better understand the molecular mechanisms associated with each. We use specific examples to emphasize both the similarities and differences between the effects of various human ribosomal protein mutations. Finally, we discuss areas of future study that are needed to further our understanding of the role of ribosome biogenesis in normal development, and possible approaches that can be used to treat debilitating ribosomopathy diseases. PMID:26442198

  16. Ribosomopathies: Global process, tissue specific defects

    PubMed Central

    Yelick, Pamela C; Trainor, Paul A

    2015-01-01

    Disruptions in ribosomal biogenesis would be expected to have global and in fact lethal effects on a developing organism. However, mutations in ribosomal protein genes have been shown in to exhibit tissue specific defects. This seemingly contradictory finding - that globally expressed genes thought to play fundamental housekeeping functions can in fact exhibit tissue and cell type specific functions ‐ provides new insight into roles for ribosomes, the protein translational machinery of the cell, in regulating normal development and disease. Furthermore it illustrates the surprisingly dynamic nature of processes regulating cell type specific protein translation. In this review, we discuss our current knowledge of a variety of ribosomal protein mutations associated with human disease, and models to better understand the molecular mechanisms associated with each. We use specific examples to emphasize both the similarities and differences between the effects of various human ribosomal protein mutations. Finally, we discuss areas of future study that are needed to further our understanding of the role of ribosome biogenesis in normal development, and possible approaches that can be used to treat debilitating ribosomopathy diseases. PMID:26442198

  17. Chairside resin-based provisional restorative materials for fixed prosthodontics.

    PubMed

    Strassler, Howard E; Lowe, Robert A

    2011-01-01

    Provisional restorations are vital to fixed prosthodontics treatment, providing an important diagnostic function while in place. In addition to protecting the prepared teeth, provisionalization enables clinicians to refine biologic and biomechanical issues before the final restoration is fabricated. Adjustments can be made in the provisional restoration to achieve both the clinician's and patient's desired results. The fabrication of temporary restorations requires that clinicians be proficient with a variety of materials and techniques that can be used to make well-adapted and functional provisionals. There are many material choices available to temporize a single crown as well as multi-unit fixed partial dentures, and the selection of provisional materials should be made based on a case-by-case evaluation. This article provides a review of polymeric resin provisional materials. PMID:22167927

  18. Atraumatic extraction, implant placement and immediate provisionalization.

    PubMed

    Tavarez, Rudys Rodolfo de Jesus; Calixto, Amanda Martins; Maia Filho, Etevaldo Matos; Bandeca, Matheus Coelho; Firoozmand, Leily Macedo; Gomes, Mario Gilson Nina; Malheiros, Adriana Santos

    2014-01-01

    Front tooth extraction typically results in significant loss of hard and soft tissue volume, both in the vestibular-lingual and mesiodistal directions. As these changes can compromise the esthetic results of prosthetic rehabilitation, extraction techniques that cause minimal trauma to the remnant tissues are applied in combination with immediate implant placement to minimize such alterations. The case reported in the present article illustrates a therapeutic plan consisting of atraumatic extraction followed by immediate implant placement and provisionalization. When carefully indicated and planned, our results indicate that this technique may provide promising immediate results relative to the maintenance and stability of the peri-implanted tissues. PMID:25576122

  19. Techniques of Fabrication of Provisional Restoration: An Overview

    PubMed Central

    Regish, K. M.; Sharma, Deeksha; Prithviraj, D. R.

    2011-01-01

    A properly fabricated provisional restoration is important in achieving a successful indirect restoration. The importance of provisional restorations as an integral part of fixed prosthodontic treatment is evident from the abundance of the literature pertaining to their importance regarding margin fidelity, function, occlusion, and esthetics. There are a variety of techniques available to suit the individual needs of the clinician and of the clinical situation, from a single unit to a complete-arch provisional fixed prostheses. PMID:22013441

  20. 78 FR 535 - Provisional Unlawful Presence Waivers of Inadmissibility for Certain Immediate Relatives

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-03

    ...On April 2, 2012, U.S. Citizenship and Immigration Services (USCIS) published a proposed rule to amend its regulations to allow certain immediate relatives of U.S. citizens who are physically present in the United States to request provisional unlawful presence waivers prior to departing from the United States for consular processing of their immigrant visa applications. This final rule......

  1. Experiment specific processing of residual acceleration data

    NASA Technical Reports Server (NTRS)

    Rogers, Melissa J. B.; Alexander, J. I. D.

    1992-01-01

    To date, most Spacelab residual acceleration data collection projects have resulted in data bases that are overwhelming to the investigator of low-gravity experiments. This paper introduces a simple passive accelerometer system to measure low-frequency accelerations. Model responses for experiments using actual acceleration data are produced and correlations are made between experiment response and the accelerometer time history in order to test the idea that recorded acceleration data and experimental responses can be usefully correlated. Spacelab 3 accelerometer data are used as input to a variety of experiment models, and sensitivity limits are obtained for particular experiment classes. The modeling results are being used to create experiment-specific residual acceleration data processing schemes for interested investigators.

  2. Virginia Tech's Off Campus Provisional Certificate Vocational Education Program.

    ERIC Educational Resources Information Center

    Duenk, Lester G.

    Virginia Tech has implemented an off-campus individualized instruction model for new, inservice, provisional certificate teachers. The program has incorporated several innovations to enhance the quality and efficiency of this approach, which has been practiced in various states for a number of years. The provisional certificate course series…

  3. Provisional materials: key components of interim fixed restorations.

    PubMed

    Perry, Ronald D; Magnuson, Britta

    2012-01-01

    Clinicians have many choices of provisional materials from which to choose when fabricating interim fixed restorations. While traditional materials are still in use today, temporary materials are continuously being updated and improved upon. In addition to the functional necessities required of the provisional material, it must also provide esthetic value for the patient. This article provides an overview of provisional materials, including newer bis-acryls that have helped eliminate some of the challenges associated with traditional acrylic materials. Composite resin preformed crowns for single-unit provisional applications are also discussed, along with CAD/CAM-fabricated materials. Regardless of the material selected, a provisional restoration must maintain and protect the underlying tooth structure from ill effects. PMID:22432178

  4. Provisional Advisory Levels (PALs) for phosgene (CG).

    PubMed

    Glass, Dana; McClanahan, Mark; Koller, Loren; Adeshina, Femi

    2009-12-01

    The Provisional Advisory Level (PAL) protocol was applied to estimate inhalation exposure limits for phosgene (CG). Three levels (PAL 1, PAL 2, and PAL 3), distinguished by severity of toxic effects, are developed for 24-hour, 30-day, 90-day, and 2-year durations of potential drinking water and inhalation exposures for the general public. For background on the PAL program and a description of the methodology used in deriving PALs, the reader is referred to accompanying papers in this Supplement. Data on humans are limited to occupational exposures or accounts from the use of phosgene as a chemical warfare agent in World War I. Animal studies with phosgene show a steep dose-response curve for pulmonary edema and mortality, with little species variability in effects. Although immediately upon exposure lacrimation and upper respiratory irritation can occur, the main effect in the target organ, a progressive pulmonary edema, occurs after a latency period of 1-24 hours. PAL estimates were approved by the Expert Consultation Panel for Provisional Advisory Levels in May 2007. Exposure limits for oral exposure to CG are not developed due to insufficient data. PAL estimates for inhalation exposure to CG are presented: The 24-hour PAL values for severity levels 1, 2, and 3 are 0.0017, 0.0033 and 0.022 ppm, respectively. The 30- and 90-day PAL values are 0.0006 and 0.0012 ppm for the PAL 1 and 2 values, respectively. These inhalation values were also accepted as the 2-year PAL 1 and 2 values because severity of lesions in the key study did not increase when exposures were extended from 4 weeks to 12 weeks. Data were not available for deriving 30-day, 90-day, and 2-year PAL 3 values. PMID:19827940

  5. Cask Processing Enclosure Specification/Operation - 12231

    SciTech Connect

    Gentry, Ronald

    2012-07-01

    Following an evaluation of throughput rates in the Hot Cell at the Transuranic Waste Processing Center and considering the variability in the waste with respect to actual dose rates a new approach to processing transuranic waste was necessary. Compounding the issue was the remote equipment poor reliability and high down-time. After considering all the factors, the evaluation resulted in the design and construction of a new waste processing area for handling the concrete casks that predominately contain contact handled transuranic (TRU) waste. The area is called the Cask Processing Enclosure and essentially the Cask Processing Enclosure mimics the projects current process techniques used for processing Contact Handled -TRU waste in the existing Box Breakdown Area and Glovebox. The Cask Processing Enclosure approach was developed based on a review of the RH processing throughput rates in the Hot Cell. As the process was reviewed consideration was given to the variability in the waste with respect to actual dose rates and the lack of equipment reliability and high wear in the Hot Cell. Based on that review, a new contact handled processing area for handling the concrete casks is being constructed and startup is expected shortly following WM2012. The Cask Processing Enclosure essentially mimics the projects current process techniques used for processing Contact Handled waste in the existing Box Breakdown Area and Glovebox and the design takes into consideration six years of operational experience. (authors)

  6. Provisional Matrix Deposition in Hemostasis and Venous Insufficiency: Tissue Preconditioning for Nonhealing Venous Ulcers

    PubMed Central

    Parker, Tony J.; Broadbent, James A.; McGovern, Jacqui A.; Broszczak, Daniel A.; Parker, Christina N.; Upton, Zee

    2015-01-01

    Significance: Chronic wounds represent a major burden on global healthcare systems and reduce the quality of life of those affected. Significant advances have been made in our understanding of the biochemistry of wound healing progression. However, knowledge regarding the specific molecular processes influencing chronic wound formation and persistence remains limited. Recent Advances: Generally, healing of acute wounds begins with hemostasis and the deposition of a plasma-derived provisional matrix into the wound. The deposition of plasma matrix proteins is known to occur around the microvasculature of the lower limb as a result of venous insufficiency. This appears to alter limb cutaneous tissue physiology and consequently drives the tissue into a ‘preconditioned’ state that negatively influences the response to wounding. Critical Issues: Processes, such as oxygen and nutrient suppression, edema, inflammatory cell trapping/extravasation, diffuse inflammation, and tissue necrosis are thought to contribute to the advent of a chronic wound. Healing of the wound then becomes difficult in the context of an internally injured limb. Thus, interventions and therapies for promoting healing of the limb is a growing area of interest. For venous ulcers, treatment using compression bandaging encourages venous return and improves healing processes within the limb, critically however, once treatment concludes ulcers often reoccur. Future Directions: Improved understanding of the composition and role of pericapillary matrix deposits in facilitating internal limb injury and subsequent development of chronic wounds will be critical for informing and enhancing current best practice therapies and preventative action in the wound care field. PMID:25785239

  7. PROVISIONAL ADVISORY LEVELS (PALs) FOR PHOSGENE (CG)

    SciTech Connect

    Glass-Mattie, Dana F; McClanahan, Mark; Koller, Loren; Adeshina, Femi; Ross, Robert Hord

    2009-01-01

    The PAL protocol was applied to estimate inhalation exposure limits for phosgene (CG). Data on humans are limited to occupational exposures or accounts from the use of phosgene as a chemical warfare agent in WWI. Animal studies with phosgene show a steep dose-response curve for pulmonary edema and mortality with little species variability in effects. Although immediately upon exposure lacrimation and upper respiratory irritation can occur, the main effect in the target organ, a progressive pulmonary edema, occurs after a latency period of 1-24 hours. PAL estimates were approved by the Expert Consultation Panel for Provisional Advisory Levels in May 2007. Exposure limits for oral exposure to CG are not developed due to insufficient data. PAL estimates for inhalation exposure to CG are presented: The 24-hour PAL values for severity levels 1, 2, and 3 are 0.0017, 0.0033 and 0.022 ppm, respectively. The 30-day PAL values are 0.0006 and 0.0012 ppm for the PAL 1 and 2 values, respectively. These 30-day inhalation values were also accepted as the 90-day and 2-year PAL 1 and 2 values. Data were not available for deriving 30-day, 90-day and 2-year PAL 3 values.

  8. Immediate maxillary lateral incisor implants with nonocclusal loading provisional crowns.

    PubMed

    Peñarrocha, Miguel; Lamas, Joana; Peñarrocha, Maria; Garcia, Berta

    2008-01-01

    This clinical report series describes a treatment modality involving immediately placed dental implants in maxillary lateral incisor sites using noncemented immediate provisional crowns retained with calcinable copings (prosthetic complement used in preparing the metal for the definitive prosthesis). Ten implants were placed in eight patients for the replacement of maxillary lateral incisors: two immediate and eight corresponding to cases of agenesis. All were subjected to immediate rehabilitation with provisional acrylic resin crowns in nonocclusal loading. One implant failed 3 weeks after placement due to acute local trauma. The other nine remained functional within the mouth, with normal clinical and radiological characteristics after a minimum of 12-month follow-up. Immediate placement of implant fixed provisional restorations retained by friction in maxillary lateral incisors offers an esthetic solution, eliminates the need for a removable provisional restoration, and avoids implant failures associated with excess cement or screw loosening. Moreover, in the case of extractions, immediate placement and provisionalization of implants in maxillary lateral incisors can effectively optimize the peri-implant esthetic results by maintaining the existing hard and soft tissue architecture of the replaced tooth. As no cement or screws are required, and the provisional crowns are placed in nonocclusal loading, the risk of complications is minimized. PMID:17927733

  9. Bacterial Adhesion of Porphyromonas Gingivalis on Provisional Fixed Prosthetic Materials

    PubMed Central

    Zortuk, Mustafa; Kesim, Servet; Kaya, Esma; Özbilge, Hatice; Kiliç, Kerem; Çölgeçen, Özlem

    2010-01-01

    Background: When provisional restorations are worn for long term period, the adhesion of bacteria becomes a primary factor in the development of periodontal diseases. The aims of this study were to evaluate the surface roughness and bacterial adhesion of four different provisional fixed prosthodon-tic materials. Methods: Ten cylindrical specimens were prepared from bis-acrylic composites (PreVISION CB and Protemp 3 Garant), a light-polymerized composite (Revotek LC), and a polymethyl methacrylate-based (Dentalon) provisional fixed prosthodontic materials. Surface roughness was assessed by profilometry. The bacterial adhesion test was applied using Porphyromonas gingivalis (P. gingivalis) and spectro-fluorometric method. Statistical analysis was performed using ANOVA and Dunnett t-tests. Results: All tested materials were significantly rougher than glass (P < 0.05). Revotek LC had the greatest fluorescence intensity, PreVISION and Protemp 3 Garant had moderate values and all of them had significantly more bacterial adhesion compared to glass (P < 0.05). Dentalon had the lowest fluorescence intensity among the provisional fixed prosthodontic materials. Conclusion: The quantity of bacterial adhesion and surface roughness differed among the assessed provisional fixed prosthodontic materials. The light-polymerized provisional material Revotek LC had rougher surface and more bacterial adhesion compared with the others. PMID:21448445

  10. System and method for deriving a process-based specification

    NASA Technical Reports Server (NTRS)

    Hinchey, Michael Gerard (Inventor); Rash, James Larry (Inventor); Rouff, Christopher A. (Inventor)

    2009-01-01

    A system and method for deriving a process-based specification for a system is disclosed. The process-based specification is mathematically inferred from a trace-based specification. The trace-based specification is derived from a non-empty set of traces or natural language scenarios. The process-based specification is mathematically equivalent to the trace-based specification. Code is generated, if applicable, from the process-based specification. A process, or phases of a process, using the features disclosed can be reversed and repeated to allow for an interactive development and modification of legacy systems. The process is applicable to any class of system, including, but not limited to, biological and physical systems, electrical and electro-mechanical systems in addition to software, hardware and hybrid hardware-software systems.

  11. A Provisional Gene Regulatory Atlas for Mouse Heart Development

    PubMed Central

    Chen, Hailin; VanBuren, Vincent

    2014-01-01

    Congenital Heart Disease (CHD) is one of the most common birth defects. Elucidating the molecular mechanisms underlying normal cardiac development is an important step towards early identification of abnormalities during the developmental program and towards the creation of early intervention strategies. We developed a novel computational strategy for leveraging high-content data sets, including a large selection of microarray data associated with mouse cardiac development, mouse genome sequence, ChIP-seq data of selected mouse transcription factors and Y2H data of mouse protein-protein interactions, to infer the active transcriptional regulatory network of mouse cardiac development. We identified phase-specific expression activity for 765 overlapping gene co-expression modules that were defined for obtained cardiac lineage microarray data. For each co-expression module, we identified the phase of cardiac development where gene expression for that module was higher than other phases. Co-expression modules were found to be consistent with biological pathway knowledge in Wikipathways, and met expectations for enrichment of pathways involved in heart lineage development. Over 359,000 transcription factor-target relationships were inferred by analyzing the promoter sequences within each gene module for overrepresentation against the JASPAR database of Transcription Factor Binding Site (TFBS) motifs. The provisional regulatory network will provide a framework of studying the genetic basis of CHD. PMID:24421884

  12. A comparison of wire- and Kevlar-reinforced provisional restorations.

    PubMed

    Powell, D B; Nicholls, J I; Yuodelis, R A; Strygler, H

    1994-01-01

    Stainless steel wire 0.036 inch in diameter was compared with Kevlar 49 polyaramid fiber as a means of reinforcing a four-unit posterior provisional fixed restoration with 2 pontics. Three reinforcement patterns for wire and two for Kevlar 49 were evaluated and compared with the control, which was an unreinforced provisional restoration. A central tensile load was placed on the cemented provisional restoration and the variables were measured: (1) the initial stiffness; (2) the load at initial fracture; and (3) the unit toughness, or the energy stored in the beam at a point where the load had undergone a 1.0-mm deflection. Statistical analysis showed (1) the bent wire configuration had a significantly higher initial stiffness (P < or = .05), (2) there was no difference between designs for load at initial fracture, and (3) the bent wire had a significantly higher unit toughness value (P < or = .05). PMID:8179789

  13. Technology and the use of acrylics for provisional dentine protection.

    PubMed

    Kapusevska, Biljana; Dereban, Nikola; Popovska, Mirjana; Nikolovska, Julijana; Radojkova Nikolovska, Vеrа; Zabokova Bilbilova, Efka; Mijoska, Aneta

    2013-01-01

    Acrylics are compounds polymerized from monomers of acrylic, metacrylic acid or acrylonitrates. The purpose of this paper is to present the technology and use of acrylics for provisional dentine protection in the practice of dental prosthodontics. For this reason, we followed 120 clinical cases from the everyday clinical practice, divided into 4 groups of 30 patients who needed prosthetic reconstruction. The first group included cases in which we applied celluloid crowns for dentine protection, for the second group we used acrylic teeth from a set of teeth for complete dentures; in the third and fourth groups the fabrication was done with the system of an impression matrix and the acrylic resin block technique respectively. In all the examined patients, the gingival index by Silness and Loe and the vitality of the dental pulp were verified clinically, after preparation and 8 days from the placement of the provisional crown. The value for dental sensitivity measured after preparation was 2.59, and 8 days after the placement of the provisional crown it bwas 3.1. From these results we can conclude that after the 8th day from the placement of the provisional crown, there was an adaptation period, characterized by a decrease in the painful sensations. The value of the Silness and Loe gingival index measured after the preparation was 1.34, and 8 days from the placement of the provisional crown was 0.94. The results inclined us to the fact that the provisional acrylic crowns facilitated the reparation of the periodontal tissue. PMID:24566021

  14. THE PEDIATRIC RHEUMATOLOGY INTERNATIONAL TRIALS ORGANIZATION PROVISIONAL CRITERIA FOR THE EVALUATION OF RESPONSE TO THERAPY IN JUVENILE DERMATOMYOSITIS

    PubMed Central

    Ruperto, Nicolino; Pistorio, Angela; Ravelli, Angelo; Rider, Lisa G.; Pilkington, Clarissa; Oliveira, Sheila; Wulffraat, Nico; Espada, Graciela; Garay, Stella; Cuttica, Ruben; Hofer, Michael; Quartier, Pierre; Melo-Gomes, Jose; Reed, Ann M.; Wierzbowska, Malgorzata; Feldman, Brian M.; Harjacek, Miroslav; Huppertz, Hans-Iko; Nielsen, Susan; Flato, Berit; Lahdenne, Pekka; Michels, Harmut; Murray, Kevin J.; Punaro, Lynn; Rennebohm, Robert; Russo, Ricardo; Balogh, Zsolt; Rooney, Madeleine; Pachman, Lauren M.; Wallace, Carol; Hashkes, Philip; Lovell, Daniel J.; Giannini, Edward H.; Martini, Alberto

    2010-01-01

    Objective To develop a provisional definition for the evaluation of response to therapy in juvenile dermatomyositis (JDM) based on the PRINTO JDM core set of variables. Methods Thirty-seven experienced pediatric rheumatologists from 27 countries, achieved consensus on 128 difficult patient profiles as clinically improved or not improved using a stepwise approach (patients rating, statistical analysis, definition selection). Using the physicians’ consensus ratings as the “gold-standard measure”, chi-square, sensitivity, specificity, false positive and negative rate, area under the ROC, and kappa agreement for candidate definitions of improvement were calculated. Definitions with kappa >0.8 were multiplied with the face validity score to select the top definitions. Results The top definition of improvement was: at least 20% improvement from baseline in 3/6 core set variables with no more than 1 of the remaining worsening by more than 30%, which cannot be muscle strength. The second highest scoring definition was at least 20% improvement from baseline in 3/6 core set variables with no more than 2 of the remaining worsening by more than 25%, which cannot be muscle strength which is definition P1 selected by the IMACS group. The third is similar to the second with the maximum amount of worsening set to 30%. This indicates convergent validity of the process. Conclusion we proposes a provisional data driven definition of improvement that reflects well the consensus rating of experienced clinicians, which incorporates clinically meaningful change in core set variables in a composite endpoint for the evaluation of global response to therapy in JDM. PMID:20583105

  15. Health-based Provisional Advisory Levels (PALs) for Homeland Security

    SciTech Connect

    Adeshina, Femi; Sonich-Mullin, Synthia; Wood, Carol S

    2009-01-01

    In compliance with Homeland Security Presidential Directive No.8, the US EPA National Homeland Security Research Center, in collaboration with the Department of Energy, is developing health-based Provisional Advisory Levels (PALs) for priority toxic industrial chemicals, pesticides, and chemical warfare agents in air and drinking water. The PALs Program will provide exposure levels to assist emergency response decision-making, and to serve as criteria for determining re-use and re-entry into affected areas resulting from transport/storage accidents, natural disasters, and subversive activities. PALs are applicable at federal, state, and local levels, and are intended for use in homeland security efforts, public health, law enforcement, and emergency response, as well as decisions by water utilities, and national and regional EPA offices. PALS have not been promulgated nor have they been formally issued as regulatory guidance. They are intended to be used at the discretion of risk managers in emergency situations when site specific risk assessments are not available. Three levels (PAL 1, PAL 2, and PAL 3), distinguished by severity of toxic effects, are developed for 24-hour, 30-day, 90-day, and 2-year durations of potential drinking water and inhalation exposures for the general public. Draft PALs are evaluated both by an EPA working group, and an external multidisciplinary panel to ensure scientific credibility and wide acceptance. In this issue, we present background information on the PAL program, the methodology used in deriving PALs, and the technical support documents for the derivation of PALs for acrylonitrile, phosgene, hydrogen chloride, and hydrogen sulfide.

  16. 21 CFR 81.1 - Provisional lists of color additives.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... affecting § 81.1, see the List of CFR Sections Affected, which appears in the Finding Aids section of the... submitted for such use or the Commissioner has been notified of studies underway to establish the safety of... provisionally listed for food, drug, and cosmetic use. Color additive Closing date Food use Drug and...

  17. 21 CFR 81.1 - Provisional lists of color additives.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... affecting § 81.1, see the List of CFR Sections Affected, which appears in the Finding Aids section of the... submitted for such use or the Commissioner has been notified of studies underway to establish the safety of... provisionally listed for food, drug, and cosmetic use. Color additive Closing date Food use Drug and...

  18. 21 CFR 81.1 - Provisional lists of color additives.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... affecting § 81.1, see the List of CFR Sections Affected, which appears in the Finding Aids section of the... submitted for such use or the Commissioner has been notified of studies underway to establish the safety of... provisionally listed for food, drug, and cosmetic use. Color additive Closing date Food use Drug and...

  19. 21 CFR 81.1 - Provisional lists of color additives.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... affecting § 81.1, see the List of CFR Sections Affected, which appears in the Finding Aids section of the... submitted for such use or the Commissioner has been notified of studies underway to establish the safety of... provisionally listed for food, drug, and cosmetic use. Color additive Closing date Food use Drug and...

  20. 14 CFR 21.223 - Class II provisional airworthiness certificates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Class II provisional airworthiness certificates. 21.223 Section 21.223 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... the aircraft has been issued to the manufacturer. (c) The applicant must submit a statement by...

  1. 14 CFR 21.221 - Class I provisional airworthiness certificates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Class I provisional airworthiness certificates. 21.221 Section 21.221 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... limitations established in §§ 21.81(e) and 91.317 of this subchapter. (b) The manufacturer must hold...

  2. Broad Classification and the Provisional Nature of Science

    ERIC Educational Resources Information Center

    McCarthy, Susan; Sanders, Martie

    2007-01-01

    This paper proposes the use of a key biological concept--broad classification--to teach the provisional and contested nature of science in school biology curricula. It also examines existing curriculum-related factors which might pose obstacles to implementing such a change. An investigation in South Africa highlights the problems regarding…

  3. Double Shell Tank (DST) Process Waste Sampling Subsystem Specification

    SciTech Connect

    RASMUSSEN, J.H.

    2000-05-03

    This specification establishes the performance requirements and provides references to the requisite codes and standards to be applied to the Double-Shell Tank (DST) Process Waste Sampling Subsystem which supports the first phase of Waste Feed Delivery.

  4. Making multiple predictable single-unit provisional restorations using an indirect technique.

    PubMed

    Hansen, Paul A; Sigler, Ernie; Husemann, R Henry

    2009-10-01

    This article describes a method to fabricate single provisional restorations for multiple preparations using an indirect technique. Provisional restorations need to mimic the definitive restoration as closely as clinically possible. When multiple adjacent provisional restorations are fabricated, the ability to make each separately, with its own path of insertion and contour, aids in providing a predictable final result for the patient. Individual provisional restorations will also allow the patient to maintain better hygiene. PMID:19782829

  5. 14 CFR 91.317 - Provisionally certificated civil aircraft: Operating limitations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Provisionally certificated civil aircraft... RULES Special Flight Operations § 91.317 Provisionally certificated civil aircraft: Operating limitations. (a) No person may operate a provisionally certificated civil aircraft unless that person...

  6. 14 CFR 91.317 - Provisionally certificated civil aircraft: Operating limitations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Provisionally certificated civil aircraft... RULES Special Flight Operations § 91.317 Provisionally certificated civil aircraft: Operating limitations. (a) No person may operate a provisionally certificated civil aircraft unless that person...

  7. 14 CFR 91.317 - Provisionally certificated civil aircraft: Operating limitations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Provisionally certificated civil aircraft... RULES Special Flight Operations § 91.317 Provisionally certificated civil aircraft: Operating limitations. (a) No person may operate a provisionally certificated civil aircraft unless that person...

  8. 14 CFR 91.317 - Provisionally certificated civil aircraft: Operating limitations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Provisionally certificated civil aircraft... RULES Special Flight Operations § 91.317 Provisionally certificated civil aircraft: Operating limitations. (a) No person may operate a provisionally certificated civil aircraft unless that person...

  9. Phonological Processing Deficits in Specific Reading Disability and Specific Language Impairment: Same or Different?

    ERIC Educational Resources Information Center

    McArthur, Genevieve; Castles, Anne

    2013-01-01

    The aim of this study was to determine if phonological processing deficits in specific reading disability (SRD) and specific language impairment (SLI) are the same or different. In four separate analyses, a different combination of reading and spoken language measures was used to divide 73 children into three subgroups: poor readers with average…

  10. Information-Processing Patterns in Specific Reading Disability.

    ERIC Educational Resources Information Center

    Watson, Catherine; Willows, Dale M.

    1995-01-01

    This study investigated specific processing strengths and weaknesses among 75 readers, ages 6-10, with no oral language deficits. Unsuccessful readers of different ages showed similar information processing patterns, and differed from successful first-grade readers on short-term auditory/working memory and decoding/encoding. Three potential…

  11. Fibronectin provides a conduit for fibroblast transmigration from collagenous stroma into fibrin clot provisional matrix.

    PubMed

    Greiling, D; Clark, R A

    1997-04-01

    After injury, the wound space is filled with a fibrin/fibronectin clot containing growth factors released by platelets and monocytes. In response to these factors, fibroblasts migrate into the fibrin clot and contribute to the formation of granulation tissue. The functional mechanisms allowing fibroblasts to leave the collagenous matrix of normal connective tissue and invade the provisional matrix of the fibrin clot have not been fully defined. To investigate these mechanisms we established a new in vitro model which simulates specific aspects of early wound healing, that is, the migration of fibroblasts from a three-dimensional collagen matrix into a fibrin clot. This transmigration could be induced by physiological concentrations of platelet releasate or platelet-derived growth factor BB (PDGF-BB) in a concentration-dependent manner. At 24 hours irradiated fibroblasts invaded the fibrin gel almost as well as non-irradiated cells, indicating that transmigration was independent of proliferation. Plasminogen and its activators appear to be necessary for invasion of the fibrin clot since protease inhibitors decreased the amount of migration. These serine proteases, however, were not necessary for exit from the collagen gel as fibroblasts migrated out of the collagen gel onto a surface coated with fibrin fibrils even in the presence of inhibitors. Removal of fibronectin (FN) from either the collagen gel or the fibrin gel markedly decreased the number of migrating cells, suggesting that FN provides a conduit for transmigration. Cell movement in the in vitro model was inhibited by RGD peptide, and by monoclonal antibodies against the subunits of the alpha5 beta1 and alpha v beta3 integrin receptor. Thus, the functional requirements for fibroblast transmigration from collagen-rich to fibrin-rich matrices, such as occurs in early wound healing, have been partially defined using an in vitro paradigm of this important biologic process. PMID:9133673

  12. Specificity, promiscuity, and the structure of complex information processing networks

    NASA Astrophysics Data System (ADS)

    Myers, Christopher

    2006-03-01

    Both the top-down designs of engineered systems and the bottom-up serendipities of biological evolution must negotiate tradeoffs between specificity and control: overly specific interactions between components can make systems brittle and unevolvable, while more generic interactions can require elaborate control in order to aggregate specificity from distributed pieces. Complex information processing systems reveal network organizations that navigate this landscape of constraints: regulatory and signaling networks in cells involve the coordination of molecular interactions that are surprisingly promiscuous, and object-oriented design in software systems emphasizes the polymorphic composition of objects of minimal necessary specificity [C.R. Myers, Phys Rev E 68, 046116 (2003)]. Models of information processing arising both in systems biology and engineered computation are explored to better understand how particular network organizations can coordinate the activity of promiscuous components to achieve robust and evolvable function.

  13. Specifications for a Federal Information Processing Standard Data Dictionary System

    NASA Technical Reports Server (NTRS)

    Goldfine, A.

    1984-01-01

    The development of a software specification that Federal agencies may use in evaluating and selecting data dictionary systems (DDS) is discussed. To supply the flexibility needed by widely different applications and environments in the Federal Government, the Federal Information Processing Standard (FIPS) specifies a core DDS together with an optimal set of modules. The focus and status of the development project are described. Functional specifications for the FIPS DDS are examined for the dictionary, the dictionary schema, and the dictionary processing system. The DDS user interfaces and DDS software interfaces are discussed as well as dictionary administration.

  14. Magnetic Field Satellite (Magsat) data processing system specifications

    NASA Technical Reports Server (NTRS)

    Berman, D.; Gomez, R.; Miller, A.

    1980-01-01

    The software specifications for the MAGSAT data processing system (MDPS) are presented. The MDPS is divided functionally into preprocessing of primary input data, data management, chronicle processing, and postprocessing. Data organization and validity, and checks of spacecraft and instrumentation are dicussed. Output products of the MDPS, including various plots and data tapes, are described. Formats for important tapes are presented. Dicussions and mathematical formulations for coordinate transformations and field model coefficients are included.

  15. 32 CFR 701.11 - Processing specific kinds of records.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 5 2012-07-01 2012-07-01 false Processing specific kinds of records. 701.11 Section 701.11 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND OFFICIAL RECORDS AVAILABILITY OF DEPARTMENT OF THE NAVY RECORDS AND PUBLICATION OF DEPARTMENT OF THE NAVY DOCUMENTS AFFECTING...

  16. Sentence Processing Factors in Adults with Specific Language Impairment

    ERIC Educational Resources Information Center

    Poll, Gerard H.

    2012-01-01

    Sentence imitation effectively discriminates between adults with and without specific language impairment (SLI). Little is known, however, about the factors that result in performance differences. This study evaluated the effects of working memory, processing speed, and argument status on sentence imitation. Working memory was measured by both a…

  17. Feedback Specificity, Information Processing, and Transfer of Training

    ERIC Educational Resources Information Center

    Goodman, Jodi S.; Wood, Robert E.; Chen, Zheng

    2011-01-01

    This study examines the effects of feedback specificity on transfer of training and the mechanisms through which feedback can enhance or inhibit transfer. We used concurrent verbal protocol methodology to elicit and operationalize the explicit information processing activities used by 48 trainees performing the Furniture Factory computer…

  18. Do Specific Relevance Instructions Promote Transfer Appropriate Processing?

    ERIC Educational Resources Information Center

    McCrudden, Matthew T.

    2011-01-01

    This study examined whether specific relevance instructions affect transfer appropriate processing. Undergraduates (n = 52) were randomly assigned to one of three pre-reading question conditions that asked them what-questions, why-questions, or to read for understanding (i.e., control condition). There were no differences in reading time across…

  19. Effect of Provisional Cements on Shear Bond Strength of Porcelain Laminate Veneers

    PubMed Central

    Altintas, Subutay Han; Tak, Onjen; Secilmis, Asli; Usumez, Aslihan

    2011-01-01

    Objectives: The purpose of this study was to evaluate the effect of three provisional cements and two cleaning techniques on the final bond strength of porcelain laminate veneers. Methods: The occlusal third of the crowns of forty molar teeth were sectioned and embedded in autopolymerizing acrylic resin. Dentin surfaces were polished and specimens were randomly divided into four groups (n=10). Provisional restorations were fabricated and two provisional restorations were cemented onto each tooth. Restorations were fixed with one of three different provisional cements: eugenol-free provisional cement (Cavex), calcium hydroxide (Dycal), and light-cured provisional cement (Tempond Clear). Provisional restorations were removed with either a dental explorer and air-water spray, or a cleaning bur (Opticlean). In the control group, provisional restorations were not used on the surfaces of specimens. IPS Empress 2 ceramic discs were luted with a dual-cured resin cement (Panavia F). Shear bond strength was measured using a universal testing machine. Data were statistically analyzed by ANOVA, Tukey’s HSD and Dunnett tests. Surfaces were examined by scanning electronic microscopy. Results: Significant differences were found between the control group and both the light-cured provisional cement groups and the eugenol-free provisional cement-cleaning bur group (P<.05). Groups that had received light-cured provisional cement showed the lowest bond strength values. Conclusions: Selection of the provisional cement is an important factor in the ultimate bond strength of the final restoration. Calcium hydroxide provisional cement and cleaning with a dental explorer are advisable. PMID:21912495

  20. [Changes in gingival blood circulation in patients with provisional fixed acrylic dentures].

    PubMed

    Shcherbakov, A S; Rudakova, Iu A; Ivanova, S B; Nekrasov, A N

    2015-01-01

    The adhesion of oral microorganisms to the surface of teeth and dental restorative materials is often the starting point in the developments of caries and periodontal disease. Formation of biofilm on the surface provisional acrylic bridge is especially quickly and can potentially generate decay or periodontal disease on the teeth. Occlusion trauma and occlusion disorders effects on increasing of injure regional periodontal tissues. Using ultrasonic doppler diagnostics oral mucosal blood flow was measured in 79 patients with periodontitis of medium severity with different hygiene conditions before and during orthopedic treatment by provisional fixed dentures was model by different methods. According to the results of this study was stated optimization of oral mucosal blood flow after pre-prosthetic treatments and the supportive hygiene periodontal care during the treatment. Results was used for reduce of functional stress in the in periodontal tissues during the orthopedic alignment by the use of fixed dentures. Specific prosthodontic hygiene protocol and model by individual articulator must be used to treat patients with widespread chronic periodontitis by interim prostheses. PMID:25909614

  1. GSFC specification electronic data processing magnetic recording tape

    NASA Technical Reports Server (NTRS)

    Tinari, D. F.; Perry, J. L.

    1980-01-01

    The design requirements are given for magnetic oxide coated, electronic data processing tape, wound on reels. Magnetic recording tape types covered by this specification are intended for use on digital tape transports using the Non-Return-to-Zero-change-on-ones (NRZI) recording method for recording densities up to and including 800 characters per inch (cpi) and the Phase-Encoding (PE) recording method for a recording density of 1600 cpi.

  2. Overview of the Standing Operating Procedures (SOP) for the Development of Provisional Advisory Levels (PALs)

    SciTech Connect

    Young, Robert; Bast, Cheryl B; Wood, Carol S; Adeshina, Femi; Ross, Robert Hord

    2009-01-01

    Provisional Advisory Levels (PALs) are concentrations in air and drinking water for priority toxic chemicals. This article summarizes the Standing Operating Procedures (SOPs) currently in place for the data-driven development of chemical-specific PALs. To provide consistency and transparency, and to avoid faults of arbitrariness, SOPs were developed for guidance in deriving PAL values. The SOPs for PAL development focus on: 1) data acquisition and analysis, 2) identification of a chemical-specific critical effect, 3) selection of a quantitative point-of-departure (POD), 4) uncertainty analysis and adjustments, 5) exposure duration adjustment and extrapolation, 6) identification of special concerns and issues, and 7) verification, documentation and dissemination of PALs. To avoid uncompromising rigidity in deriving PAL values and to allow for incorporation of new or refined methodologies, the overall procedure is fluid and subject to modification. The purpose of this publication is to provide a summary of these SOPs.

  3. Topicality matters: position-specific demands on Chinese discourse processing.

    PubMed

    Hung, Yu-Chen; Schumacher, Petra B

    2012-03-01

    We report an event-related potential study designed to explore the nature of context-induced topicality in Chinese discourse processing. Topic is what an utterance is about and represents the most prominent discourse element, which occurs sentence-initially in Chinese. We tested question-answer pairs consisting of topic and non-topic questions followed by different continuations (Topic-Continuity, Topic-Shift, Novel-Topic). ERPs were measured at distinct sentential positions and revealed that sentence-initially information processing is guided by topicality, which affects N400 and Late Positivity effects alike. In non-initial positions, the given-new distinction is the dominant principle, also modulating N400 and Late Positivity. The language processor hence utilizes a few core operations for information processing that depend on position-specific constraints. PMID:22266598

  4. Provisional hourly values of equatorial Dst for 1971

    NASA Technical Reports Server (NTRS)

    Sugiura, M.; Poros, D. J.

    1972-01-01

    Tables and plots of provisional hourly values of the equatorial Dst index for 1971 are given, a table of daily mean Dst values for 1971 is also provided. The base line values for the four observatories, Hermanus, Kakioka, Honolulu, and San Juan, were obtained from extrapolations using the coefficients for the secular variations determined for the previous years. Examining the Dst values for quiet days, the base lines so determined appear to be slightly low, so that the Dst index for quiet periods tends to be high.

  5. Results of the first provisional technical secretariat interlaboratory comparison test

    SciTech Connect

    Stuff, J.R.; Hoffland, L.

    1995-06-01

    The principal task of this laboratory in the first Provisional Technical Secretariat (PTS) Interlaboratory Comparison Test was to verify and test the extraction and preparation procedures outlined in the Recommended Operating Procedures for Sampling and Analysis in the Verification of Chemical Disarmament in addition to our laboratory extraction methods and our laboratory analysis methods. Sample preparation began on 16 May 1994 and analysis was completed on 12 June 1994. The analytical methods used included NMR ({sup 1}H and {sup 31}P) GC/AED, GC/MS (EI and methane CI), GC/IRD, HPLC/IC, HPLC/TSP/MS, MS/MS(Electrospray), and CZE.

  6. Provisional Crown Dislodgement during Scuba Diving: A Case of Barotrauma

    PubMed Central

    Gulve, Meenal Nitin; Gulve, Nitin Dilip

    2013-01-01

    Changes in ambient pressure, for example, during flying, diving, or hyperbaric oxygen therapy, can lead to barotrauma. Although it may seem that this issue was neglected in dental education and research in recent decades, familiarity with and understanding of these facts may be of importance for dental practitioners. We report the case of a patient who experienced barotrauma involving dislodgement of a provisional crown during scuba diving. Patients who are exposed to pressure changes as a part of their jobs or hobbies and their dentists should know the causes of barotrauma. In addition, the clinician must be aware of the possible influence of pressure changes on the retention of dental components. PMID:23984113

  7. Provisional Crown Dislodgement during Scuba Diving: A Case of Barotrauma.

    PubMed

    Gulve, Meenal Nitin; Gulve, Nitin Dilip

    2013-01-01

    Changes in ambient pressure, for example, during flying, diving, or hyperbaric oxygen therapy, can lead to barotrauma. Although it may seem that this issue was neglected in dental education and research in recent decades, familiarity with and understanding of these facts may be of importance for dental practitioners. We report the case of a patient who experienced barotrauma involving dislodgement of a provisional crown during scuba diving. Patients who are exposed to pressure changes as a part of their jobs or hobbies and their dentists should know the causes of barotrauma. In addition, the clinician must be aware of the possible influence of pressure changes on the retention of dental components. PMID:23984113

  8. Production of a Fixed Provisional Restoration Using an Acrylic Denture: Technique and Case Report

    PubMed Central

    2015-01-01

    The damage or loss of anterior teeth causes a negative impact on the patient in many ways. In adolescents and young patients, the provisional replacement with artificial teeth may minimize this impact. Many approaches have been described for provisional restorations. This article discusses about a chairside fixed provisional restoration technique that was adjusted into the edentulous area of a 15-year-old girl. PMID:26393221

  9. Disgust-specific modulation of early attention processes.

    PubMed

    van Hooff, Johanna C; van Buuringen, Melanie; El M'rabet, Ihsane; de Gier, Margot; van Zalingen, Lilian

    2014-10-01

    Although threatening images are known to attract and keep our attention, little is known about the existence of emotion-specific attention effects. In this study (N=46), characteristics of an anticipated, disgust-specific effect were investigated by means of a covert orienting paradigm incorporating pictures that were either disgust-evoking, fear-evoking, happiness-evoking or neutral. Attention adhesion to these pictures was measured by the time necessary to identify a peripheral target, presented 100, 200, 500, or 800 ms after picture onset. Main results showed that reaction times were delayed for targets following the disgust-evoking pictures by 100 and 200 ms, suggesting that only these pictures temporarily grabbed hold of participants' attention. These delays were similar for ignore- and attend-instructions, and they were not affected by the participants' anxiety levels or disgust sensitivity. The disgust-specific influence on early attention processes thus appeared very robust, occurring in the majority of participants and without contribution of voluntary- and strategic-attention processes. In contrast, a smaller and less reliable effect of all emotional (arousing) pictures was present in the form of delayed responding in the 100 ms cue-target interval. This effect was more transitory and apparent only in participants with relatively high state-anxiety scores. Practical and theoretical consequences of these findings are discussed. PMID:25226546

  10. The application of time series forecasting methods to an estimation problem using provisional mortality statistics.

    PubMed

    Katzoff, M

    1989-03-01

    Provisional estimates of mortality for selected causes of death are published each month by the National Center for Health Statistics. These estimates are based upon a ten per cent sample of death certificates in the United States. Final mortality results, based upon all the death certificates for a calendar year, are available one to two years after publication of the provisional estimates. This paper explores the potential of time series forecasting techniques for improving mortality estimates by using the correlation structure between the provisional and final series to obtain mortality estimates that are expected to be closer to final values than currently used provisional estimates. PMID:2711064

  11. NDE Process Development Specification for SRB Composite Nose Cap

    NASA Technical Reports Server (NTRS)

    Suits, M.

    1999-01-01

    The Shuttle Upgrade program is a continuing improvement process to enable the Space Shuttle to be an effective space transportation vehicle for the next few decades. The Solid Rocket Booster (SRB), as a component of that system, is currently undergoing such an improvement. Advanced materials, such as composites, have given us a chance to improve performance and to reduce weight. The SRB Composite Nose Cap (CNC) program aims to replace the current aluminum nose cap, which is coated with a Thermal Protection System and poses a possible debris hazard, with a lighter, stronger, CNC. For the next 2 years, this program will evaluate the design, material selection, properties, and verification of the CNC. This particular process specification cites the methods and techniques for verifying the integrity of such a nose cap with nondestructive evaluation.

  12. Mechanical Properties and Simulated Wear of Provisional Resin Materials.

    PubMed

    Takamizawa, T; Barkmeier, W W; Tsujimoto, A; Scheidel, D; Erickson, R L; Latta, M A; Miyazaki, M

    2015-01-01

    The purpose of this study was to determine flexural properties and erosive wear behavior of provisional resin materials. Three bis-acryl base provisional resins-1) Protemp Plus (PP), 2) Integrity (IG), 3) Luxatemp Automix Plus (LX)-and a conventional poly(methylmethacrylate) (PMMA) resin, UniFast III (UF), were evaluated. A resin composite, Z100 Restorative (Z1), was included as a benchmark material. Six specimens for each of the four materials were used to determine flexural strength and elastic modulus according to ISO Standard 4049. Twelve specimens for each material were used to examine wear using a generalized wear simulation model. The test materials were each subjected to wear challenges of 25,000, 50,000, 100,000, and 200,000 cycles in a Leinfelder-Suzuki (Alabama) wear simulator. The materials were placed in custom cylinder-shaped stainless-steel fixtures, and wear was generated using a cylindrical-shaped flat-ended stainless-steel antagonist in a slurry of nonplasticized PMMA beads. Wear (mean facet depth [μm] and volume loss [mm(3)]) was determined using a noncontact profilometer (Proscan 2100) with Proscan and AnSur 3D software. The laboratory data were evaluated using two-way analysis of variance (ANOVA; factors: 1) material and 2) cycles) followed by Tukey HSD post hoc test (α=0.05). The flexural strength ranged from 68.2 to 150.6 MPa, and the elastic modulus ranged from 2.0 to 15.9 GPa. All of the bis-acryl provisional resins (PP, IG, and LX) demonstrated significantly higher values than the PMMA resin (UF) in flexural strength and elastic modulus (p<0.05). However, there was no significant difference (p>0.05) in flexural properties among three bis-acryl base provisional resins (PP, IG, and LX). Z1 demonstrated significantly (p<0.05) higher flexural strength and elastic modulus than the other materials tested. The results for mean facet wear depth (μm) and standard deviations (SD) for 200,000 cycles were as follows: PP, 22.4 (5.0); IG, 51.0 (6

  13. Evidence-based provisional clinical classification criteria for autoinflammatory periodic fevers.

    PubMed

    Federici, Silvia; Sormani, Maria Pia; Ozen, Seza; Lachmann, Helen J; Amaryan, Gayane; Woo, Patricia; Koné-Paut, Isabelle; Dewarrat, Natacha; Cantarini, Luca; Insalaco, Antonella; Uziel, Yosef; Rigante, Donato; Quartier, Pierre; Demirkaya, Erkan; Herlin, Troels; Meini, Antonella; Fabio, Giovanna; Kallinich, Tilmann; Martino, Silvana; Butbul, Aviel Yonatan; Olivieri, Alma; Kuemmerle-Deschner, Jasmin; Neven, Benedicte; Simon, Anna; Ozdogan, Huri; Touitou, Isabelle; Frenkel, Joost; Hofer, Michael; Martini, Alberto; Ruperto, Nicolino; Gattorno, Marco

    2015-05-01

    The objective of this work was to develop and validate a set of clinical criteria for the classification of patients affected by periodic fevers. Patients with inherited periodic fevers (familial Mediterranean fever (FMF); mevalonate kinase deficiency (MKD); tumour necrosis factor receptor-associated periodic fever syndrome (TRAPS); cryopyrin-associated periodic syndromes (CAPS)) enrolled in the Eurofever Registry up until March 2013 were evaluated. Patients with periodic fever, aphthosis, pharyngitis and adenitis (PFAPA) syndrome were used as negative controls. For each genetic disease, patients were considered to be 'gold standard' on the basis of the presence of a confirmatory genetic analysis. Clinical criteria were formulated on the basis of univariate and multivariate analysis in an initial group of patients (training set) and validated in an independent set of patients (validation set). A total of 1215 consecutive patients with periodic fevers were identified, and 518 gold standard patients (291 FMF, 74 MKD, 86 TRAPS, 67 CAPS) and 199 patients with PFAPA as disease controls were evaluated. The univariate and multivariate analyses identified a number of clinical variables that correlated independently with each disease, and four provisional classification scores were created. Cut-off values of the classification scores were chosen using receiver operating characteristic curve analysis as those giving the highest sensitivity and specificity. The classification scores were then tested in an independent set of patients (validation set) with an area under the curve of 0.98 for FMF, 0.95 for TRAPS, 0.96 for MKD, and 0.99 for CAPS. In conclusion, evidence-based provisional clinical criteria with high sensitivity and specificity for the clinical classification of patients with inherited periodic fevers have been developed. PMID:25637003

  14. Targeting and Processing of Site-specific DNA Interstrand Crosslinks

    PubMed Central

    Vasquez, Karen M.

    2010-01-01

    DNA interstrand crosslinks (ICLs) are among the most cytotoxic types of DNA damage, and thus ICL-inducing agents such as cyclophosphamide, melphalan, cisplatin, psoralen and mitomycin C have been used clinically as anti-cancer drugs for decades. ICLs can also be formed endogenously as a consequence of cellular metabolic processes. ICL-inducing agents continue to be among the most effective chemotherapeutic treatments for many cancers; however, treatment with these agents can lead to secondary malignancies, in part due to mutagenic processing of the DNA lesions. The mechanisms of ICL repair have been characterized more thoroughly in bacteria and yeast than in mammalian cells. Thus, a better understanding the molecular mechanisms of ICL processing offers the potential to improve the efficacy of these drugs in cancer therapy. In mammalian cells it is thought that ICLs are repaired by the coordination of proteins from several pathways, including nucleotide excision repair (NER), base excision repair (BER), mismatch repair (MMR), homologous recombination (HR), translesion synthesis (TLS), and proteins involved in Fanconi anemia (FA). In this review, we focus on the potential functions of NER, MMR, and HR proteins in the repair of and response to ICLs in human cells and in mice. We will also discuss a unique approach, using psoralen covalently linked to triplex-forming oligonucleotides to direct ICLs to specific sites in the mammalian genome. PMID:20196133

  15. 75 FR 1356 - RC2 Corporation, Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-11

    ... From the Federal Register Online via the Government Publishing Office CONSUMER PRODUCT SAFETY COMMISSION RC2 Corporation, Provisional Acceptance of a Settlement Agreement and Order AGENCY: Consumer... settlements which it provisionally accepts under the Consumer Product Safety Act in the Federal Register...

  16. Provisional Assessment of Recent Studies on Health Effects of Particulate Matter Exposure

    EPA Science Inventory

    This report presents the findings of EPA’s survey and provisional assessment of studies published since the completion of the 2009 PM ISA. EPA has screened and surveyed the recent literature and developed a provisional assessment that places those studies of potentially greatest ...

  17. 14 CFR 21.81 - Requirements for issue and amendment of Class I provisional type certificates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Requirements for issue and amendment of Class I provisional type certificates. 21.81 Section 21.81 Aeronautics and Space FEDERAL AVIATION... Type Certificates § 21.81 Requirements for issue and amendment of Class I provisional type...

  18. 14 CFR 21.83 - Requirements for issue and amendment of Class II provisional type certificates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Requirements for issue and amendment of Class II provisional type certificates. 21.83 Section 21.83 Aeronautics and Space FEDERAL AVIATION... Type Certificates § 21.83 Requirements for issue and amendment of Class II provisional...

  19. 75 FR 55777 - Pro-Pac Distributing Corp., Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-14

    ... COMMISSION Pro-Pac Distributing Corp., Provisional Acceptance of a Settlement Agreement and Order AGENCY... check payable to the order of the United States Treasury. 18. Upon provisional acceptance of the... is published in the Federal Register. 19. Upon the Commission's final acceptance of the Agreement...

  20. 76 FR 37793 - Viking Range Corporation, Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-28

    ... COMMISSION Viking Range Corporation, Provisional Acceptance of a Settlement Agreement and Order AGENCY.... 16. Upon provisional acceptance of the Agreement by the Commission, the Agreement shall be placed on.... Upon the Commission's final acceptance of the Agreement and issuance of the final Order,...

  1. 76 FR 55648 - Sunsations Inc., Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-08

    ... COMMISSION Sunsations Inc., Provisional Acceptance of a Settlement Agreement and Order AGENCY: Consumer..., standards, and/or bans enforced and administered by the Commission. 27. Upon provisional acceptance of the... is published in the Federal Register. 28. Upon the Commission's final acceptance of the Agreement...

  2. 76 FR 61042 - Modification of Regulations Regarding the Practice of Accepting Bonds During the Provisional...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-03

    ... Antidumping and Countervailing Duty Investigations, 76 FR 23225 (April 26, 2011) (Proposed Rule). The Proposed... Practice of Accepting Bonds During the Provisional Measures Period in Antidumping and Countervailing Duty... practice of accepting bonds during the provisional measures period in AD and CVD investigations....

  3. 10 CFR 903.21 - Completion of rate development; provisional rates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Completion of rate development; provisional rates. 903.21... Participation in Power and Transmission Rate Adjustments and Extensions for the Alaska, Southeastern, Southwestern, and Western Area Power Administrations § 903.21 Completion of rate development; provisional...

  4. Developing a provisional standard for clinical supervision in nursing and health visiting: the methodological trail.

    PubMed

    Rafferty, Mic; Jenkins, Emrys; Parke, Sian

    2003-12-01

    The authors outline the process that led to the development of a provisional professional standard for clinical supervision, focusing on design, data collection, and analysis methods. The work was undertaken in an ethos of new paradigm/fifth-generation approaches and used the "manifold of subjective knowing" to gain a holistic understanding of supervisors' experience as represented by experiential, presentational, propositional, and practical knowing. They show how they arrived at the indicators of the standard: Professional Support, Learning, and Accountability. Each of these indicators consists of further elements related to Time, Environment, Relationship (Professional Support), Focus, Knowledge, Interventions (Learning), Organizational Support, Recording, and Competency (Accountability). Findings confirm that clinical supervision practice is complex, and the authors describe proportionally complex methods of analysis. PMID:14658356

  5. Fermentation process using specific oxygen uptake rates as a process control

    SciTech Connect

    Van Hoek, Pim; Aristidou, Aristos; Rush, Brian

    2011-05-10

    Specific oxygen uptake (OUR) is used as a process control parameter in fermentation processes. OUR is determined during at least the production phase of a fermentation process, and process parameters are adjusted to maintain the OUR within desired ranges. The invention is particularly applicable when the fermentation is conducted using a microorganism having a natural PDC pathway that has been disrupted so that it no longer functions. Microorganisms of this sort often produce poorly under strictly anaerobic conditions. Microaeration controlled by monitoring OUR allows the performance of the microorganism to be optimized.

  6. Fermentation process using specific oxygen uptake rates as a process control

    SciTech Connect

    Van Hoek; Pim , Aristidou; Aristos , Rush; Brian

    2007-06-19

    Specific oxygen uptake (OUR) is used as a process control parameter in fermentation processes. OUR is determined during at least the production phase of a fermentation process, and process parameters are adjusted to maintain the OUR within desired ranges. The invention is particularly applicable when the fermentation is conducted using a microorganism having a natural PDC pathway that has been disrupted so that it no longer functions. Microorganisms of this sort often produce poorly under strictly anaerobic conditions. Microaeration controlled by monitoring OUR allows the performance of the microorganism to be optimized.

  7. Fermentation process using specific oxygen uptake rates as a process control

    SciTech Connect

    Van Hoek, Pim; Aristidou, Aristos; Rush, Brian

    2014-09-09

    Specific oxygen uptake (OUR) is used as a process control parameter in fermentation processes. OUR is determined during at least the production phase of a fermentation process, and process parameters are adjusted to maintain the OUR within desired ranges. The invention is particularly applicable when the fermentation is conducted using a microorganism having a natural PDC pathway that has been disrupted so that it no longer functions. Microorganisms of this sort often produce poorly under strictly anaerobic conditions. Microaeration controlled by monitoring OUR allows the performance of the microorganism to be optimized.

  8. Fermentation process using specific oxygen uptake rates as a process control

    DOEpatents

    Van Hoek, Pim; Aristidou, Aristos; Rush, Brian J.

    2016-08-30

    Specific oxygen uptake (OUR) is used as a process control parameter in fermentation processes. OUR is determined during at least the production phase of a fermentation process, and process parameters are adjusted to maintain the OUR within desired ranges. The invention is particularly applicable when the fermentation is conducted using a microorganism having a natural PDC pathway that has been disrupted so that it no longer functions. Microorganisms of this sort often produce poorly under strictly anaerobic conditions. Microaeration controlled by monitoring OUR allows the performance of the microorganism to be optimized.

  9. Correlations between adolescent processing speed and specific spindle frequencies

    PubMed Central

    Nader, Rebecca S.; Smith, Carlyle T.

    2015-01-01

    Sleep spindles are waxing and waning thalamocortical oscillations with accepted frequencies of between 11 and 16 Hz and a minimum duration of 0.5 s. Our research has suggested that there is spindle activity in all of the sleep stages, and thus for the present analysis we examined the link between spindle activity (Stage 2, rapid eye movement (REM) and slow wave sleep (SWS)) and waking cognitive abilities in 32 healthy adolescents. After software was used to filter frequencies outside the desired range, slow spindles (11.00–13.50 Hz), fast spindles (13.51–16.00 Hz) and spindle-like activity (16.01–18.50 Hz) were observed in Stage 2, SWS and REM sleep. Our analysis suggests that these specific EEG frequencies were significantly related to processing speed, which is one of the subscales of the intelligence score, in adolescents. The relationship was prominent in SWS and REM sleep. Further, the spindle-like activity (16.01–18.50 Hz) that occurred during SWS was strongly related to processing speed. Results suggest that the ability of adolescents to respond to tasks in an accurate, efficient and timely manner is related to their sleep quality. These findings support earlier research reporting relationships between learning, learning potential and sleep spindle activity in adults and adolescents. PMID:25709575

  10. The effect of fiber reinforcement type and water storage on strength properties of a provisional fixed partial denture resin.

    PubMed

    Uzun, Gülay; Keyf, Filiz

    2003-04-01

    unreinforced resin. The aramid-reinforced resin decreased from 62.29 to 58.77 MPa. The addition of fiber reinforcement enhanced the physical properties (the transverse strength, the maximal deflection, the modulus of elasticity) of the processed material over that seen with no addition of fiber. Water storage did not statistically affect the transverse strength of the provisional denture resin compared to that of the unreinforced resin. The transverse strength was lowered at water storage but it was not statistically significant. The transverse strength was enhanced by fiber addition compared to the unreinforced resin. The glass fiber was superior to the other fiber. Also the modulus of elasticity was enhanced by fiber addition compared to the unreinforced resin. PMID:12797420

  11. Evidence for auditory-visual processing specific to biological motion.

    PubMed

    Wuerger, Sophie M; Crocker-Buque, Alexander; Meyer, Georg F

    2012-01-01

    Biological motion is usually associated with highly correlated sensory signals from more than one modality: an approaching human walker will not only have a visual representation, namely an increase in the retinal size of the walker's image, but also a synchronous auditory signal since the walker's footsteps will grow louder. We investigated whether the multisensorial processing of biological motion is subject to different constraints than ecologically invalid motion. Observers were presented with a visual point-light walker and/or synchronised auditory footsteps; the walker was either approaching the observer (looming motion) or walking away (receding motion). A scrambled point-light walker served as a control. Observers were asked to detect the walker's motion as quickly and as accurately as possible. In Experiment 1 we tested whether the reaction time advantage due to redundant information in the auditory and visual modality is specific for biological motion. We found no evidence for such an effect: the reaction time reduction was accounted for by statistical facilitation for both biological and scrambled motion. In Experiment 2, we dissociated the auditory and visual information and tested whether inconsistent motion directions across the auditory and visual modality yield longer reaction times in comparison to consistent motion directions. Here we find an effect specific to biological motion: motion incongruency leads to longer reaction times only when the visual walker is intact and recognisable as a human figure. If the figure of the walker is abolished by scrambling, motion incongruency has no effect on the speed of the observers' judgments. In conjunction with Experiment 1 this suggests that conflicting auditory-visual motion information of an intact human walker leads to interference and thereby delaying the response. PMID:22353566

  12. 45 CFR 264.70 - What makes a State eligible to receive a provisional payment of contingency funds?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... provisional payment of contingency funds? 264.70 Section 264.70 Public Welfare Regulations Relating to Public... Contingency Fund? § 264.70 What makes a State eligible to receive a provisional payment of contingency funds? (a) In order to receive a provisional payment of contingency funds, a State must: (1) Be a...

  13. The lasting effects of process-specific versus stimulus-specific learning during infancy.

    PubMed

    Hadley, Hillary; Pickron, Charisse B; Scott, Lisa S

    2015-09-01

    The capacity to tell the difference between two faces within an infrequently experienced face group (e.g. other species, other race) declines from 6 to 9 months of age unless infants learn to match these faces with individual-level names. Similarly, the use of individual-level labels can also facilitate differentiation of a group of non-face objects (strollers). This early learning leads to increased neural specialization for previously unfamiliar face or object groups. The current investigation aimed to determine whether early conceptual learning between 6 and 9 months leads to sustained behavioral advantages and neural changes in these same children at 4-6 years of age. Results suggest that relative to a control group of children with no previous training and to children with infant category-level naming experience, children with early individual-level training exhibited faster response times to human faces. Further, individual-level training with a face group - but not an object group - led to more adult-like neural responses for human faces. These results suggest that early individual-level learning results in long-lasting process-specific effects, which benefit categories that continue to be perceived and recognized at the individual level (e.g. human faces). PMID:25439095

  14. Technique for making full-coverage provisional restorations on teeth with insufficient clinical crowns.

    PubMed

    Feinberg, Edward

    2010-11-01

    Provisional restorations fabricated with copper bands are tremendous practice builders, eliminating the sensitivity, recurrent decay and poor retention that are common with conventional temporary restorations. The copper-band provisional restoration is the ideal choice when conventional butt-joint temporary restorations are unsuitable. The technique for making this restoration is demonstrated in this article with a step-by-step "how-to" description. An analysis of the basic principles and theories behind the success of the copper band provisional restoration is also presented, as well as a discussion of the restoration's advantages and disadvantages. PMID:21226402

  15. 29 CFR 780.816 - Processing of specific commodities.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Employment in Ginning of Cotton and Processing of Sugar Beets, Sugar-Beet Molasses, Sugarcane, or Maple Sap... processing of sugar beets, sugar-beet molasses, sugarcane, or maple sap is within the exemption....

  16. 29 CFR 780.816 - Processing of specific commodities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Employment in Ginning of Cotton and Processing of Sugar Beets, Sugar-Beet Molasses, Sugarcane, or Maple Sap... processing of sugar beets, sugar-beet molasses, sugarcane, or maple sap is within the exemption....

  17. 29 CFR 780.816 - Processing of specific commodities.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Employment in Ginning of Cotton and Processing of Sugar Beets, Sugar-Beet Molasses, Sugarcane, or Maple Sap... processing of sugar beets, sugar-beet molasses, sugarcane, or maple sap is within the exemption....

  18. 29 CFR 780.816 - Processing of specific commodities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Employment in Ginning of Cotton and Processing of Sugar Beets, Sugar-Beet Molasses, Sugarcane, or Maple Sap... processing of sugar beets, sugar-beet molasses, sugarcane, or maple sap is within the exemption....

  19. In vitro study of fracture strength of provisional crown materials

    PubMed Central

    Sayin, Gulsum; Kara, Ozlem

    2015-01-01

    PURPOSE The purpose of this report was to evaluate the effect of the fabrication method and material type on the fracture strength of provisional crowns. MATERIALS AND METHODS A master model with one crown (maxillary left second premolar) was manufactured from Cr-Co alloy. The master model was scanned, and the data set was transferred to a CAD/CAM unit (Yenamak D50, Yenadent Ltd, Istanbul, Turkey) for the Cercon Base group. For the other groups, temporary crowns were produced by direct fabrication methods (Imident, Temdent, Structur Premium, Takilon, Systemp c&b II, and Acrytemp). The specimens were subjected to water storage at 37℃ for 24 hours, and then they were thermocycled (TC, 5000×, 5-55℃) (n=10). The maximum force at fracture (Fmax) was measured in a universal test machine at 1 mm/min. Data was analyzed by non-parametric statistics (α=.05). RESULTS Fmax values varied between 711.09-1392.1 N. In the PMMA groups, Takilon showed the lowest values (711.09 N), and Cercon Base showed the highest values (959.59 N). In the composite groups, Structur Premium showed the highest values (1392.1 N), and Acrytemp showed the lowest values (910.05 N). The composite groups showed significantly higher values than the PMMA groups (P=.01). CONCLUSION Composite-based materials showed significantly higher fracture strengths than PMMA-based materials. The CAD-CAM technique offers more advantages than the direct technique. PMID:25722834

  20. LADTAG Progress 2010 and Plans for 2011 and Provisional PELs from Lavage and Blood Data

    NASA Technical Reports Server (NTRS)

    James, John T.

    2010-01-01

    This viewgraph presentation reviews the Lunar Airborne Dust Toxicity Assessment Group (LADTAG) plans and progress for 2010 and 2011. Provisional Permissible Exposure Limits (PPELs) from lavage fluid and blood data are also presented.

  1. Reverse spot bonding: a novel technique for provisionalization with immediate dentin sealing.

    PubMed

    Schoenbaum, Todd R; Ercus, Sebastian; Snowden, John

    2012-05-01

    Described here is a clinical technique for the creation of predictable, stable, and efficient provisionals in combination with the use of immediate dentin sealing for partial-coverage posterior ceramic restorations. PMID:22616222

  2. 77 FR 44593 - Burlington Coat Factory Warehouse Corporation, Provisional Acceptance of a Settlement Agreement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ... COMMISSION Burlington Coat Factory Warehouse Corporation, Provisional Acceptance of a Settlement Agreement... accepted Settlement Agreement with Burlington Coat Factory Warehouse Corporation, containing a civil... Factory Warehouse Corporation CPSC Docket No. 12-C0008 Settlement Agreement 1. In accordance with...

  3. 20 CFR 416.999c - How do we determine provisional benefits?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... FOR THE AGED, BLIND, AND DISABLED Determining Disability and Blindness Continuing Or Stopping Disability Or Blindness § 416.999c How do we determine provisional benefits? (a) You may receive up to...

  4. 20 CFR 416.999c - How do we determine provisional benefits?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... FOR THE AGED, BLIND, AND DISABLED Determining Disability and Blindness Continuing Or Stopping Disability Or Blindness § 416.999c How do we determine provisional benefits? (a) You may receive up to...

  5. 20 CFR 416.999c - How do we determine provisional benefits?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... FOR THE AGED, BLIND, AND DISABLED Determining Disability and Blindness Continuing Or Stopping Disability Or Blindness § 416.999c How do we determine provisional benefits? (a) You may receive up to...

  6. 20 CFR 416.999c - How do we determine provisional benefits?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... FOR THE AGED, BLIND, AND DISABLED Determining Disability and Blindness Continuing Or Stopping Disability Or Blindness § 416.999c How do we determine provisional benefits? (a) You may receive up to...

  7. 20 CFR 416.999c - How do we determine provisional benefits?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... FOR THE AGED, BLIND, AND DISABLED Determining Disability and Blindness Continuing Or Stopping Disability Or Blindness § 416.999c How do we determine provisional benefits? (a) You may receive up to...

  8. Long-Term Provisional Bonded Composite Restorations Make Full-Mouth Rehabilitation Possible.

    PubMed

    Wilkins, Ronald G

    2016-05-01

    Full-mouth rehabilitation cases frequently require an extended period to complete. In this case involving a patient who presented with a significant amount of lost tooth structure, treatment featured laboratory-fabricated composite provisional restorations aimed at stabilizing the dentition and enabling definitive treatment to be completed in segments. The approach taken allowed occlusal and esthetic issues to be resolved through use of the provisionals while minimizing tooth preparation. The technique provided immediate improvement in esthetics, function, and comfort. PMID:27213778

  9. 76 FR 79656 - E & B Giftware LLC, Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ...It is the policy of the Commission to publish settlements which it provisionally accepts under the Consumer Product Safety Act in the Federal Register in accordance with the terms of 16 CFR 1118.20(e). Published below is a provisionally-accepted Settlement Agreement with E & B Giftware LLC, containing a civil penalty of $550,000.00, of which $50,000 shall be suspended, within twenty (20) days......

  10. Processing of virus-specific glycoproteins of varicella zoster virus

    SciTech Connect

    Namazue, J.; Campo-Vera, H.; Kitamura, K.; Okuno, T.; Yamanishi, K.

    1985-05-01

    Monoclonal antibodies to varicella zoster virus (VZV) glycoproteins were used to study the processing of three glycoproteins with molecular weights of 83K-94K (gp 2), 64K (gp 3), and 55K (gp 5). Immunoprecipitation experiments performed with VZV-infected cells, pulse labeled with (/sup 3/H)glucosamine in the presence of tunicamycin, suggest that O-linked oligosaccharide is present on the glycoprotein of gp 2. Use of the enzyme endo-beta-N-acetylglucosaminidase H revealed that the fully processed form of gp 3 had high-mannose type and that of gp 5 had only complex type of N-linked oligosaccharides. Experiments with monensin suggest that the precursor form (116K) of gp 3 is cleaved during the processing from Golgi apparatus to cell surface membrane. The extension of O-linked oligosaccharide chain and the complex type of N-linked oligosaccharide chains also occurs during this processing.

  11. Estimating provisional acceptable residues for extralabel drug use in livestock.

    PubMed

    Baynes, R E; Martín-Jiménez, T; Craigmill, A L; Riviere, J E

    1999-06-01

    In 1996, the United States Congress passed legislation (Animal Medicinal Drug Use Clarification Act, AMDUCA), which allows some veterinary or human drugs to be used off label in food-producing animals. In order to implement this Act and protect the U.S. consumer, tolerances or safe concentrations are required before a withdrawal time can be estimated for extralabel drug use. Use of foreign MRLs to satisfy these data needs may not be applicable because of differences in safety standards between the U.S. and other countries. This paper presents strategies that can be used to derive equivalent safe concentrations, referred to as provisional acceptable residues (PARs), that may then be used to estimate drug withdrawal times. Health-based methods are proposed for calculating a PAR for a tissue. Procedure A partitions 50% of the acceptable daily intake (ADI) to edible tissues and reserves the remainder for milk. Procedure B equally partitions the ADI into all edible tissues. Procedure C partitions 50% of the ADI to milk and equally partitions the remaining 50% ADI into edible tissues. Simulations were performed for florfenicol, tetracycline, dexamethasone, azaperone, ivermectin, eprinomectin, and doramectin. In general, these simulations resulted in derivation of conservative PARs, which did not result in daily intakes of residues greater than the health-based ADI. These simulations demonstrated that provided the safe concentrations or equivalent PARs are based on rigorous toxicology safety data (e.g., NOELs, ADIs), the safety of food animal products will not be compromised. It is proposed that these PARs can be used for estimating withdrawal times after extralabel drug use or inadvertent exposure to an environmental contaminant where no approved withdrawal time exists. Finally, implementing similar transparent methods could have a positive impact on international harmonization and trade. PMID:10388614

  12. Developing a provisional and national renal disease registry for Iran

    PubMed Central

    Ajami, Sima; Askarianzadeh, Mahdi; Mortazavi, Mojgan

    2015-01-01

    Background: Disease registry is a database that includes information about people suffering a special kind of disease. The aim of this study was to first identify and compare the National Renal Disease Registry (NRDR) characteristics in some countries with Iran; and second, develop a provisional and NRDR for Iran. Materials and Methods: Retrieval of data of the NRDR was performed by scholars responsible in related agencies, including the Ministry of Health and Medical Education, Renal Disease charity, and data registries in the United States, United Kingdom, Malaysia, and Iran. This research was applied, and the study was descriptive-comparative. The study population consisted of the NRDR in selected countries in which data were collected by forms that were designed according to the study objectives. Sources of data were researchers, articles, books, journals, databases, websites, related documents, and people who are active in this regard, and related agencies, including the Ministry of Health and Medical Education, and patient support charity. The researchers collected data for each country based on the study objectives and then put them in comparative tables. Data were analyzed by descriptive, comparative, and theoretical methods. Results: Most of the renal transplant teams report their own results as a single center experiences. America and Britain have a preeminent national registry of renal disease compared to other countries. Conclusion: Given that control, prevention, and treatment of chronic renal diseases incur high expenses and the disease is one of leading mortality factors in Iran and across the world and since national registry system for chronic renal diseases can provide better tools and strategies to manage and evaluate patients’ characteristics as well as risk factors which eventually leads to making better decisions. PMID:26109970

  13. Health-based Provisional Advisory Levels (PALs) for homeland security.

    PubMed

    Adeshina, Femi; Sonich-Mullin, Cynthia; Ross, Robert H; Wood, Carol S

    2009-12-01

    The Homeland Security Presidential Directive #8 (HSPD-8) for National Emergency Preparedness was issued to " establish policies to strengthen the preparedness of the United States to prevent and respond to threatened or actual domestic terrorist attacks, major disasters, and other emergencies by requiring a national domestic all- hazards preparedness goal. "In response to HSPD-8 and HSPD-22 (classified) on Domestic Chemical Defense, the US Environmental Protection Agency (US EPA) National Homeland Security Research Center (NHSRC) is developing health-based Provisional Advisory Levels (PALs) for priority chemicals (including chemical warfare agents, pesticides, and toxic industrial chemicals) in air and drinking water. PALs are temporary values that will neither be promulgated, nor be formally issued as regulatory guidance. They are intended to be used at the discretion of risk managers in emergency situations. The PAL Program provides advisory exposure levels for chemical agents to assist in emergency planning and response decision-making, and to aid in making informed risk management decisions for evacuation, temporary re-entry into affected areas, and resumed-use of infrastructure, such as water resources. These risk management decisions may be made at the federal, state, and local levels. Three exposure levels (PAL 1, PAL 2, and PAL 3), distinguished by severity of toxic effects, are developed for 24-hour, 30-day, 90-day, and 2-year durations for potential exposure to drinking water and ambient air by the general public. Developed PALs are evaluated both by a US EPA working group, and an external multidisciplinary panel to ensure scientific credibility and wide acceptance. In this Special Issue publication, we present background information on the PAL program, the methodology used in deriving PALs, and the technical support documents for the derivation of PALs for acrylonitrile, hydrogen sulfide, and phosgene. PMID:19814653

  14. Mathematical Formulation Requirements and Specifications for the Process Models

    SciTech Connect

    Steefel, C.; Moulton, D.; Pau, G.; Lipnikov, K.; Meza, J.; Lichtner, P.; Wolery, T.; Bacon, D.; Spycher, N.; Bell, J.; Moridis, G.; Yabusaki, S.; Sonnenthal, E.; Zyvoloski, G.; Andre, B.; Zheng, L.; Davis, J.

    2010-11-01

    The Advanced Simulation Capability for Environmental Management (ASCEM) is intended to be a state-of-the-art scientific tool and approach for understanding and predicting contaminant fate and transport in natural and engineered systems. The ASCEM program is aimed at addressing critical EM program needs to better understand and quantify flow and contaminant transport behavior in complex geological systems. It will also address the long-term performance of engineered components including cementitious materials in nuclear waste disposal facilities, in order to reduce uncertainties and risks associated with DOE EM's environmental cleanup and closure activities. Building upon national capabilities developed from decades of Research and Development in subsurface geosciences, computational and computer science, modeling and applied mathematics, and environmental remediation, the ASCEM initiative will develop an integrated, open-source, high-performance computer modeling system for multiphase, multicomponent, multiscale subsurface flow and contaminant transport. This integrated modeling system will incorporate capabilities for predicting releases from various waste forms, identifying exposure pathways and performing dose calculations, and conducting systematic uncertainty quantification. The ASCEM approach will be demonstrated on selected sites, and then applied to support the next generation of performance assessments of nuclear waste disposal and facility decommissioning across the EM complex. The Multi-Process High Performance Computing (HPC) Simulator is one of three thrust areas in ASCEM. The other two are the Platform and Integrated Toolsets (dubbed the Platform) and Site Applications. The primary objective of the HPC Simulator is to provide a flexible and extensible computational engine to simulate the coupled processes and flow scenarios described by the conceptual models developed using the ASCEM Platform. The graded and iterative approach to assessments naturally

  15. Specifics of processing SRS lidar signals in GHz frequency range

    NASA Astrophysics Data System (ADS)

    Grishkanich, A. S.; Elizarov, V. V.; Kascheev, S. V.; Zhevlakov, A. P.; Sidorov, I. S.

    2015-12-01

    One of the highly effective methods of operative remote environmental monitoring on land and water surfaces is laser sensing. It knew that the Raman scattering cross section is very small (10-25-10-27), so in some cases radiation back into captivity to the target could be a few tens of photons. For high-speed sensing, speed of processing and ease of use lidar units required for the use of appropriate hardware and software systems used for the decision of tasks of collecting, processing, storing, organizing large amounts of data.

  16. 29 CFR 780.816 - Processing of specific commodities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... into Sugar or Syrup; Exemption From Overtime Pay Requirements Under Section 13(b)(15) County Where... the production of unrefined sugar or syrup. For example, sorghum cane or refinery syrup (which is a byproduct of refined syrup) are not named commodities and employees engaged in processing these products...

  17. Auditory Temporal Processing as a Specific Deficit among Dyslexic Readers

    ERIC Educational Resources Information Center

    Fostick, Leah; Bar-El, Sharona; Ram-Tsur, Ronit

    2012-01-01

    The present study focuses on examining the hypothesis that auditory temporal perception deficit is a basic cause for reading disabilities among dyslexics. This hypothesis maintains that reading impairment is caused by a fundamental perceptual deficit in processing rapid auditory or visual stimuli. Since the auditory perception involves a number of…

  18. School Processes Mediate School Compositional Effects: Model Specification and Estimation

    ERIC Educational Resources Information Center

    Liu, Hongqiang; Van Damme, Jan; Gielen, Sarah; Van Den Noortgate, Wim

    2015-01-01

    School composition effects have been consistently verified, but few studies ever attempted to study how school composition affects school achievement. Based on prior research findings, we employed multilevel mediation modeling to examine whether school processes mediate the effect of school composition upon school outcomes based on the data of 28…

  19. Process of labeling specific chromosomes using recombinant repetitive DNA

    DOEpatents

    Moyzis, R.K.; Meyne, J.

    1988-02-12

    Chromosome preferential nucleotide sequences are first determined from a library of recombinant DNA clones having families of repetitive sequences. Library clones are identified with a low homology with a sequence of repetitive DNA families to which the first clones respectively belong and variant sequences are then identified by selecting clones having a pattern of hybridization with genomic DNA dissimilar to the hybridization pattern shown by the respective families. In another embodiment, variant sequences are selected from a sequence of a known repetitive DNA family. The selected variant sequence is classified as chromosome specific, chromosome preferential, or chromosome nonspecific. Sequences which are classified as chromosome preferential are further sequenced and regions are identified having a low homology with other regions of the chromosome preferential sequence or with known sequences of other family members and consensus sequences of the repetitive DNA families for the chromosome preferential sequences. The selected low homology regions are then hybridized with chromosomes to determine those low homology regions hybridized with a specific chromosome under normal stringency conditions.

  20. Provisional Tic Disorder: What to tell parents when their child first starts ticcing

    PubMed Central

    Black, Kevin J; Black, Elizabeth Rose; Greene, Deanna J.; Schlaggar, Bradley L.

    2016-01-01

    The child with recent onset of tics is a common patient in a pediatrics or child neurology practice. If the child’s first tic was less than a year in the past, the diagnosis is usually Provisional Tic Disorder (PTD). Published reviews by experts reveal substantial consensus on prognosis in this situation: the tics will almost always disappear in a few months, having remained mild while they lasted. Surprisingly, however, the sparse existing data may not support these opinions. PTD may have just as much importance for science as for clinical care. It provides an opportunity to prospectively observe the spontaneous remission of tics. Such prospective studies may aid identification of genes or biomarkers specifically associated with remission rather than onset of tics. A better understanding of tic remission may also suggest novel treatment strategies for Tourette syndrome, or may lead to secondary prevention of tic disorders. This review summarizes the limited existing data on the epidemiology, phenomenology, and outcome of PTD, highlights areas in which prospective study is sorely needed, and proposes that tic disorders may completely remit much less often than is generally believed. PMID:27158458

  1. Provisional Tic Disorder: What to tell parents when their child first starts ticcing.

    PubMed

    Black, Kevin J; Black, Elizabeth Rose; Greene, Deanna J; Schlaggar, Bradley L

    2016-01-01

    The child with recent onset of tics is a common patient in a pediatrics or child neurology practice. If the child's first tic was less than a year in the past, the diagnosis is usually Provisional Tic Disorder (PTD). Published reviews by experts reveal substantial consensus on prognosis in this situation: the tics will almost always disappear in a few months, having remained mild while they lasted. Surprisingly, however, the sparse existing data may not support these opinions. PTD may have just as much importance for science as for clinical care. It provides an opportunity to prospectively observe the spontaneous remission of tics. Such prospective studies may aid identification of genes or biomarkers specifically associated with remission rather than onset of tics. A better understanding of tic remission may also suggest novel treatment strategies for Tourette syndrome, or may lead to secondary prevention of tic disorders. This review summarizes the limited existing data on the epidemiology, phenomenology, and outcome of PTD, highlights areas in which prospective study is sorely needed, and proposes that tic disorders may completely remit much less often than is generally believed. PMID:27158458

  2. Immediate occlusal loading in edentulous jaws, CT-guided surgery and fixed provisional prosthesis: a maxillary arch clinical report.

    PubMed

    Drago, Carl; del Castillo, Robert; Peterson, Thomas

    2011-04-01

    Immediate occlusal loading (IOL) in edentulous jaws has been reported in numerous publications with implant cumulative survival rates consistent with conventional, unloaded healing protocols. Computed Tomography (CT)-guided surgery has more recently been developed and accepted as an additional treatment modality for maxillary and mandibular implant placement, with or without IOL. Reports as to the accuracy of planned versus actual implant placement in CT-guided surgeries have indicated that CT-guided surgery is not 100% accurate; standard deviations have been reported with values between 1 and 2 mm in terms of actual versus planned placement. The purpose of this article is to review the clinical parameters associated with IOL, and CT-guided surgery in edentulous jaws; and to present a clinical case illustrating the clinical and laboratory phases of treatment. The illustrated treatment was accomplished with an IOL protocol and includes fabrication and placement of a laboratory-processed provisional maxillary prosthesis. This particular protocol had slightly increased costs relative to conventional implant placement; however, the clinicians and patient benefited from improved accuracy of the provisional prostheses and decreased chairtime for the clinical procedures. The benefits and limitations of this treatment protocol are also discussed. PMID:21070431

  3. Physiologically-based pharmacokinetic model for Fentanyl in support of the development of Provisional Advisory Levels

    SciTech Connect

    Shankaran, Harish; Adeshina, Femi; Teeguarden, Justin G.

    2013-12-15

    Provisional Advisory Levels (PALs) are tiered exposure limits for toxic chemicals in air and drinking water that are developed to assist in emergency responses. Physiologically-based pharmacokinetic (PBPK) modeling can support this process by enabling extrapolations across doses, and exposure routes, thereby addressing gaps in the available toxicity data. Here, we describe the development of a PBPK model for Fentanyl – a synthetic opioid used clinically for pain management – to support the establishment of PALs. Starting from an existing model for intravenous Fentanyl, we first optimized distribution and clearance parameters using several additional IV datasets. We then calibrated the model using pharmacokinetic data for various formulations, and determined the absorbed fraction, F, and time taken for the absorbed amount to reach 90% of its final value, t90. For aerosolized pulmonary Fentanyl, F = 1 and t90 < 1 min indicating complete and rapid absorption. The F value ranged from 0.35 to 0.74 for oral and various transmucosal routes. Oral Fentanyl was absorbed the slowest (t90 ∼ 300 min); the absorption of intranasal Fentanyl was relatively rapid (t90 ∼ 20–40 min); and the various oral transmucosal routes had intermediate absorption rates (t90 ∼ 160–300 min). Based on these results, for inhalation exposures, we assumed that all of the Fentanyl inhaled from the air during each breath directly, and instantaneously enters the arterial circulation. We present model predictions of Fentanyl blood concentrations in oral and inhalation scenarios relevant for PAL development, and provide an analytical expression that can be used to extrapolate between oral and inhalation routes for the derivation of PALs. - Highlights: • We develop a Fentanyl PBPK model for relating external dose to internal levels. • We calibrate the model to oral and inhalation exposures using > 50 human datasets. • Model predictions are in good agreement with the available

  4. Substrate-specific kinetics of Dicer-catalyzed RNA Processing

    PubMed Central

    Chakravarthy, Srinivas; Sternberg, Samuel H.; Kellenberger, Colleen; Doudna, Jennifer A.

    2010-01-01

    Summary The specialized ribonuclease Dicer plays a central role in eukaryotic gene expression by producing small regulatory RNAs – miRNAs and siRNAs – from larger double stranded RNA (dsRNA) substrates. Although Dicer will cleave both imperfectly base-paired hairpin structures (pre-miRNAs) and perfect duplexes (pre-siRNAs) in vitro, it has not been clear whether these are mechanistically equivalent substrates and how dsRNA binding proteins such as TRBP influence substrate selection and RNA processing efficiency. We show here that human Dicer is much faster at processing a pre-miRNA substrate compared to a pre-siRNA substrate under both single and multiple turnover conditions. Maximal cleavage rates (Vmax) calculated by Michaelis-Menten analysis differed by more than 100-fold under multiple turnover conditions. TRBP was found to enhance dicing of both substrates to similar extents, and this stimulation required the two N-terminal dsRNA binding domains of TRBP. These results demonstrate that multiple factors influence dicing kinetics. While TRBP stimulates dicing by enhancing the stability of Dicer-substrate complexes, Dicer itself generates product RNAs at rates determined at least in part by the structural properties of the substrate. PMID:20932845

  5. Guardbanding specifications with SPC (statistical process control) application

    SciTech Connect

    Kirkpatrick, R.L.

    1987-09-01

    A reasonable assumption in the manufacture and measurement of a product characteristic is that test set variation contributes to the observed random variation of the characteristic in addition to the product variation. A Supplier may use test limits (guardbands) set inside specification limits to preclude the sending of nonconforming product to the Buyer. The Supplier's goals are for very few or no misclassifications of product (especially bad called good) in the Supplier's accepted product which would be submitted to the Buyer. Meeting these goals depends on several factors. This paper reviews an example; quantifies the influencing factors of the product percent defective, the ratio of gage variation to product variation and the guardband limits; provides tables of the misclassification percentages to illustrate the effects of changing these factors; and discusses SPC ratios that may already be available to a user to estimate these factors for the further understanding of the practice of guardbanding. With estimates of these influencing factors, one could make a reasonable setting of a guardband. 6 refs., 7 tabs.

  6. File Specification for GEOS-5 FP (Forward Processing)

    NASA Technical Reports Server (NTRS)

    Lucchesi, R.

    2013-01-01

    horizontal grid. The majority of data products are time-averaged, but four instantaneous products are also available. Hourly data intervals are used for two-dimensional products, while 3-hourly intervals are used for three-dimensional products. These may be on the model's native 72-layer vertical grid or at 42 pressure surfaces extending to 0.1 hPa. This document describes the gridded output files produced by the GMAO near real-time operational FP, using the most recent version of the GEOS-5 assimilation system. Additional details about variables listed in this file specification can be found in a separate document, the GEOS-5 File Specification Variable Definition Glossary. Documentation about the current access methods for products described in this document can be found on the GMAO products page: http://gmao.gsfc.nasa.gov/products/.

  7. Apolipoprotein E isoform-specific effects on lipoprotein receptor processing

    PubMed Central

    Bachmeier, Corbin; Shackleton, Ben; Ojo, Joseph; Paris, Daniel; Mullan, Michael; Crawford, Fiona

    2014-01-01

    Recent findings indicate an isoform-specific role for apolipoprotein E (apoE) in the elimination of beta-amyloid (Aβ) from the brain. ApoE is closely associated with various lipoprotein receptors, which contribute to Aβ brain removal via metabolic clearance or transit across the blood-brain barrier (BBB). These receptors are subject to ectodomain shedding at the cell surface, which alters endocytic transport and mitigates Aβ elimination. To further understand the manner in which apoE influences Aβ brain clearance, these studies investigated the effect of apoE on lipoprotein receptor shedding. Consistent with prior reports, we observed an increased shedding of the low density lipoprotein receptor (LDLR) and the LDLR-related protein 1 (LRP1) following Aβ exposure in human brain endothelial cells. When Aβ was co-treated with each apoE isoform, there was a reduction in Aβ-induced shedding with apoE2 and apoE3, while lipoprotein receptor shedding in the presence of apoE4 remained elevated. Likewise, intracranial administration of Aβ to apoE targeted replacement mice (expressing the human apoE isoforms) resulted in an isoform-dependent effect on lipoprotein receptor shedding in the brain (apoE4>apoE3>apoE2). Moreover, these results show a strong inverse correlation with our prior work in apoE transgenic mice in which apoE4 animals showed reduced Aβ clearance across the BBB compared to apoE3 animals. Based on these results, apoE4 appears less efficient than other apoE isoforms in regulating lipoprotein receptor shedding, which may explain the differential effects of these isoforms in removing Aβ from the brain. PMID:25015123

  8. In vitro color stability of provisional crown and bridge restoration materials.

    PubMed

    Ergün, Gülfem; Mutlu-Sagesen, Lâmia; Ozkan, Yalçin; Demirel, Erol

    2005-09-01

    Discoloration of provisional restorations can be an esthetic problem, especially when the treatment plan requires long-term provisionalization. In this study, therefore, we examined the effects of staining solution on the color stability of these provisional crown and bridge restoration materials: Structur, Temdent, and Tab 2000. Treatment solutions were namely carrot juice, tea, cola, light cola, and distilled water. Thirty samples were prepared for each type of provisional material, such that a total of 90 samples were prepared. The color value of each sample was measured with a colorimeter at baseline and after one day, one week, two weeks, and four weeks of immersion in various treatment solutions. Results were determined using the CIELAB system. Color change data were calculated and subjected to two-way analysis of variance. To examine significant interactions, one-way ANOVA and Tukey's multiple comparisons test were performed to identify differences between the solutions (p < or = 0.05). After four weeks of treatment, color difference values were found to range from 0.20 to 3.99 deltaE* units. The highest color difference values were obtained in carrot juice, cola, and tea with Structur samples after four weeks, where these values were categorized as "noticeable" and "unacceptable" color change values. Based on the results of this study, we do not recommend amine-containing Structur to be used as a provisional crown and bridge restorative material for treatments of a longer duration. PMID:16279724

  9. Summary of some feasibility studies for site-specific solar industrial process heat

    SciTech Connect

    1982-01-01

    Some feasibility studies for several different site specific solar industrial process heat applications are summarized. The followng applications are examined. Leather Tanning; Concrete Production: Lumber and Paper Processing; Milk Processing; Molding, Curing or Drying; Automobile Manufacture; and Food Processing and Preparation. For each application, site and process data, system design, and performance and cost estimates are summarized.

  10. 80 FR 45206 - Notice of LG Electronics Tianjin Appliance Co., Ltd. and LG Electronics USA Inc., Provisional...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2015-07-29

    ... LG Electronics USA Inc. A footnote was omitted from the SUMMARY paragraph of the document. FOR... COMMISSION Notice of LG Electronics Tianjin Appliance Co., Ltd. and LG Electronics USA Inc., Provisional... a document in the Federal Register of July 24, 2015, concerning the provisional acceptance of...

  11. 75 FR 14144 - Availability for Non-Exclusive, Exclusive, or Partially Exclusive Licensing of U.S. Provisional...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-24

    ... invention. ADDRESSES: Commander, U.S. Army Medical Research and Materiel Command, ATTN: Command Judge.... Provisional Patent Application Concerning Medical Delivery System AGENCY: Department of the Army, DoD. ACTION.... Provisional Patent Application Serial No. 61/ ] 312,908 entitled ``Medical Delivery System,'' filed March...

  12. 78 FR 3883 - The Bon-Ton Stores, Inc., Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-17

    ... COMMISSION The Bon-Ton Stores, Inc., Provisional Acceptance of a Settlement Agreement and Order AGENCY... violated CPSA's reporting requirements. 18. Upon provisional acceptance of the Agreement by the Commission... with 16 CFR 1118.20(f). 19. Upon the Commission's final acceptance of the Agreement and issuance of...

  13. 75 FR 4793 - Availability for Non-Exclusive, Exclusive, or Partially Exclusive Licensing of U.S. Provisional...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    .... Provisional Patent Application Concerning Blast Wave Sensor AGENCY: Department of the Army, DoD. ACTION.... Provisional Patent Application Serial No. 61/292,095 entitled ``Blast Wave Sensor,'' filed January 4, 2010...) 619-5034. SUPPLEMENTARY INFORMATION: The invention relates to blast wave sensors and their use...

  14. Encoding and Retrieving Faces and Places: Distinguishing Process- and Stimulus-Specific Differences in Brain Activity

    ERIC Educational Resources Information Center

    Prince, Steven E.; Dennis, Nancy A.; Cabeza, Roberto

    2009-01-01

    Among the most fundamental issues in cognitive neuroscience is how the brain may be organized into process-specific and stimulus-specific regions. In the episodic memory domain, most functional neuroimaging studies have focused on the former dimension, typically investigating the neural correlates of various memory processes. Thus, there is little…

  15. 78 FR 14080 - Kolcraft Enterprises, Inc., Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-04

    ... COMMISSION Kolcraft Enterprises, Inc., Provisional Acceptance of a Settlement Agreement and Order AGENCY... Agreement with Kolcraft Enterprises, Inc., containing a civil penalty of $400,000.00, within twenty (20...), and 16 CFR 1118.20, Kolcraft Enterprises, Inc. (Kolcraft) and staff (staff) of the United...

  16. 76 FR 58784 - Bad Boy Enterprises, LLC, Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-22

    ... From the Federal Register Online via the Government Publishing Office CONSUMER PRODUCT SAFETY...: Consumer Product Safety Commission. ACTION: Notice. SUMMARY: It is the policy of the Commission to publish settlements which it provisionally accepts under the Consumer Product Safety Act in the Federal Register...

  17. 77 FR 58098 - Haier America Trading, LLC, Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    ... From the Federal Register Online via the Government Publishing Office CONSUMER PRODUCT SAFETY...: Consumer Product Safety Commission. ACTION: Notice. SUMMARY: It is the policy of the Commission to publish settlements which it provisionally accepts under the Consumer Product Safety Act in the Federal Register...

  18. Radiation safety of crew and passengers of air transportation in civil aviation. Provisional standards

    SciTech Connect

    Aksenov, A.F.; Burnazyan, A.I.

    1985-03-01

    The purpose and application of the provisional standards for radiation safety of crew and passengers in civil aviation are given. The radiation effect of cosmic radiation in flight on civil aviation air transport is described. Standard levels of radiation and conditions of radiation safety are discussed.

  19. Radiation safety of crew and passengers of air transportation in civil aviation. Provisional standards

    NASA Technical Reports Server (NTRS)

    Aksenov, A. F.; Burnazyan, A. I.

    1985-01-01

    The purpose and application of the provisional standards for radiation safety of crew and passengers in civil aviation are given. The radiation effect of cosmic radiation in flight on civil aviation air transport is described. Standard levels of radiation and conditions of radiation safety are discussed.

  20. Directory of Documentation and Information Services in Adult Education. Provisional Edition.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). Adult Education Div.

    The directory was prepared as part of a comprehensive effort for improving the international network for the exchange of documentation, information, ideas, and experiences, in the field of adult education. The provisional edition will be corrected and updated after March 1976. A work-sheet and coding instructions are included for this purpose. In…

  1. 20 CFR 404.1592e - How do we determine provisional benefits?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false How do we determine provisional benefits? 404... in April 2004. His disability benefit had previously terminated in January 2003. Since Mr. K meets... beginning April 2004 while we determine whether he is disabled and whether his current impairment(s) is...

  2. 20 CFR 404.1592e - How do we determine provisional benefits?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false How do we determine provisional benefits? 404... in April 2004. His disability benefit had previously terminated in January 2003. Since Mr. K meets... beginning April 2004 while we determine whether he is disabled and whether his current impairment(s) is...

  3. 14 CFR 91.317 - Provisionally certificated civil aircraft: Operating limitations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Provisionally certificated civil aircraft: Operating limitations. 91.317 Section 91.317 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... type or supplemental type certification of that aircraft; (2) For training flight crews,...

  4. 20 CFR 404.1592e - How do we determine provisional benefits?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... monthly provisional benefit amount equal to the last monthly benefit payable to you during your prior... amount under § 404.270. The last monthly benefit payable is the amount of the monthly insurance benefit... other factors for possible reinstatement (i.e., his prior entitlement was terminated within the last...

  5. 38 CFR 17.65 - Approvals and provisional approvals of community residential care facilities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... approvals of community residential care facilities. 17.65 Section 17.65 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Community Residential Care § 17.65 Approvals and provisional approvals of community residential care facilities. (a) An approval of a facility meeting all...

  6. 38 CFR 17.65 - Approvals and provisional approvals of community residential care facilities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... approvals of community residential care facilities. 17.65 Section 17.65 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Community Residential Care § 17.65 Approvals and provisional approvals of community residential care facilities. (a) An approval of a facility meeting all...

  7. 78 FR 36571 - North American Datum of 1983 (NAD 83) Outer Continental Shelf (OCS) Provisional Official...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR Bureau of Ocean Energy Management North American Datum of 1983 (NAD 83) Outer Continental Shelf (OCS) Provisional Official Protraction Diagram (OPDs) AGENCY: Bureau of Ocean Energy Management (BOEM),...

  8. 31 CFR 240.6 - Provisional credit; first examination; declination; final payment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 2 2014-07-01 2014-07-01 false Provisional credit; first examination; declination; final payment. 240.6 Section 240.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE FISCAL SERVICE INDORSEMENT AND PAYMENT OF CHECKS DRAWN ON...

  9. ELECTRON MICROSCOPE MEASUREMENT OF AIRBORNE ASBESTOS CONCENTRATIONS - A PROVISIONAL METHODOLOGY MANUAL

    EPA Science Inventory

    This manual describes a provisional optimum electron microscope (EM) procedure for measuring the concentration of asbestos in air samples. The main features of the method include depositing an air sample on a polycarbonate membrane filter, examining an EM grid specimen in a trans...

  10. ELECTRON MICROSCOPE MEASUREMENT OF AIRBORNE ASBESTOS CONCENTRATIONS. A PROVISIONAL METHODOLOGY MANUAL

    EPA Science Inventory

    This manual describes a provisional optimum electron microscope (EM) procedure for measuring the concentration of asbestos in air samples. The main features of the method include depositing an air sample on a polycarbonate membrane filter, examining an EM grid specimen in a trans...

  11. 76 FR 49453 - CVS Pharmacy, Inc., Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... Product Safety Commission. ACTION: Notice. SUMMARY: It is the policy of the Commission to publish settlements which it provisionally accepts under the Consumer Product Safety Act in the Federal Register in... knowingly violated the CPSA and asserts that at the time it sold the Jackets, CVS did not have...

  12. 77 FR 4023 - Hewlett-Packard Company, Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-26

    ...: Consumer Product Safety Commission. ACTION: Notice. SUMMARY: It is the policy of the Commission to publish settlements which it provisionally accepts under the Consumer Product Safety Act in the Federal Register in.... Between March 2007 and April 2007, HP conducted a study, from which it obtained additional...

  13. 76 FR 49751 - Perfect Fitness, Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-11

    ... Product Safety Commission. ACTION: Notice. SUMMARY: It is the policy of the Commission to publish settlements which it provisionally accepts under the Consumer Product Safety Act in the Federal Register in... death, and denies that it knowingly violated the reporting requirements of Section 15(b) of the CPSA,...

  14. 76 FR 63906 - Henry Gordy International, Inc., Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-14

    ...: Consumer Product Safety Commission. ACTION: Notice. SUMMARY: It is the policy of the Commission to publish settlements which it provisionally accepts under the Consumer Product Safety Act in the Federal Register in... their mouth, the dart can be inhaled into the throat and it can prevent the child from breathing....

  15. 76 FR 6453 - Raynor Marketing, Ltd., Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-04

    ...: Consumer Product Safety Commission. ACTION: Notice. SUMMARY: It is the policy of the Commission to publish settlements which it provisionally accepts under the Consumer Product Safety Act in the Federal Register in... create an unreasonable risk of serious injury or death, and denies that it violated the...

  16. 78 FR 27190 - Williams-Sonoma, Inc., Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-09

    ... Product Safety Commission. ACTION: Notice. SUMMARY: It is the policy of the Commission to publish settlements which it provisionally accepts under the Consumer Product Safety Act in the Federal Register in..., where it was hidden from view, there sometimes was no outward indication to consumers that the wood...

  17. 77 FR 63801 - Aqua-Leisure Industries, Inc., Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ...: Consumer Product Safety Commission. ACTION: Notice. SUMMARY: It is the policy of the Commission to publish settlements which it provisionally accepts under the Consumer Product Safety Act in the Federal Register in... filed a Supplemental Full Report in which it reported that the Firm had received at least 28...

  18. 75 FR 26939 - Target Corporation: Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-13

    ... Product Safety Commission. ACTION: Notice. SUMMARY: It is the policy of the Commission to publish settlements which it provisionally accepts under the Consumer Product Safety Act in the Federal Register in..., 2006, Target submitted a Full Report to CPSC containing information that it had commissioned...

  19. 76 FR 41487 - Macy's, Inc., Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-14

    ... Safety Commission. ACTION: Notice. SUMMARY: It is the policy of the Commission to publish settlements which it provisionally accepts under the Consumer Product Safety Act in the Federal Register in... agrees that it will not seek or accept, directly or indirectly, indemnification, reimbursement,...

  20. 76 FR 10339 - Ms. Bubbles, Inc., Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ... COMMISSION Ms. Bubbles, Inc., Provisional Acceptance of a Settlement Agreement and Order AGENCY: Consumer... Agreement with Ms. Bubbles, Inc., containing a civil penalty of $40,000.00. \\1\\ The Commission voted 5-0 to... Matter of Ms. Bubbles, Inc.; SETTLEMENT AGREEMENT 1. In accordance with 16 C.F.R. Sec. 1118.20,...

  1. 75 FR 76405 - Winter Bee, Inc., Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-08

    ... COMMISSION Winter Bee, Inc., Provisional Acceptance of a Settlement Agreement and Order AGENCY: Consumer... Agreement with Winter Bee, Inc., containing a civil penalty of $200,000.00, to be suspended except for $40.... Settlement Agreement 1. In accordance with 16 CFR 1118.20, Winter Bee, Inc. (``Winter Bee'') and the...

  2. Student Financial Aid, Academic Year 2011-12. First Look. (Provisional Data). NCES 2013-178

    ERIC Educational Resources Information Center

    Ginder, Scott A.; Kelly-Reid, Janice E.

    2013-01-01

    The Integrated Postsecondary Education Data System (IPEDS) collects institution-level data from postsecondary institutions in the United States (50 states and the District of Columbia) and other U.S. jurisdictions (see appendix A for a list of other U.S. jurisdictions). This "First Look" presents findings from the provisional data of the IPEDS…

  3. 10 CFR 903.21 - Completion of rate development; provisional rates.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... into effect on an interim basis (Provisional Rates); or (3) develop rates which in the Administrator's judgment should be confirmed, approved, and placed into effect by the FERC on a final basis without being placed into effect on an interim basis. A statement shall be prepared and made available to the...

  4. 31 CFR 240.6 - Provisional credit; first examination; declination; final payment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... substitute check, Treasury has a warranty or indemnity claim arising under 12 CFR 229.52 or 229.53. (d... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false Provisional credit; first examination... credit; first examination; declination; final payment. (a) Any credit issued by a Federal Reserve Bank...

  5. 31 CFR 240.6 - Provisional credit; first examination; declination; final payment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... substitute check, Treasury has a warranty or indemnity claim arising under 12 CFR 229.52 or 229.53. (d... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Provisional credit; first examination... credit; first examination; declination; final payment. (a) Any credit issued by a Federal Reserve Bank...

  6. Cross-modal comparisons of stimulus specificity and commonality in phonological processing.

    PubMed

    Oron, A; Wolak, T; Zeffiro, T; Szelag, E

    2016-01-01

    Phonological processing is a fundamental ability which underlies language comprehension. Functional neuroanatomy of phonology constitutes a matter of ongoing debate. In the present study, subjects performed visual (rhyme detection) and auditory (identification of spoken words starting with a given consonant) tasks that were contrasted with matched nonverbal tasks. We identified regions critical for phonological processing which were either stimulus specific or supramodal. The results revealed a high degree of modality specificity in both visual and auditory networks. Moreover, we observed a modality independent region in the left middle temporal gyrus (MTG)/superior temporal sulcus (STS), between a more anterior temporal area with auditory specificity and a more posterior temporal area with visual specificity. This dissociation in functional neuroanatomy suggests that this area may be a core region for supramodal phonological processing, acting as a gateway between spatially separate, but stimulus specific, phonological processes and more general linguistic functions. PMID:26994741

  7. Delivering Software Process-Specific Project Courses in Tertiary Education Environment: Challenges and Solution

    ERIC Educational Resources Information Center

    Rong, Guoping; Shao, Dong

    2012-01-01

    The importance of delivering software process courses to software engineering students has been more and more recognized in China in recent years. However, students usually cannot fully appreciate the value of software process courses by only learning methodology and principle in the classroom. Therefore, a process-specific project course was…

  8. Cognitive Risk Factors for Specific Learning Disorder: Processing Speed, Temporal Processing, and Working Memory.

    PubMed

    Moll, Kristina; Göbel, Silke M; Gooch, Debbie; Landerl, Karin; Snowling, Margaret J

    2016-05-01

    High comorbidity rates between reading disorder (RD) and mathematics disorder (MD) indicate that, although the cognitive core deficits underlying these disorders are distinct, additional domain-general risk factors might be shared between the disorders. Three domain-general cognitive abilities were investigated in children with RD and MD: processing speed, temporal processing, and working memory. Since attention problems frequently co-occur with learning disorders, the study examined whether these three factors, which are known to be associated with attention problems, account for the comorbidity between these disorders. The sample comprised 99 primary school children in four groups: children with RD, children with MD, children with both disorders (RD+MD), and typically developing children (TD controls). Measures of processing speed, temporal processing, and memory were analyzed in a series of ANCOVAs including attention ratings as covariate. All three risk factors were associated with poor attention. After controlling for attention, associations with RD and MD differed: Although deficits in verbal memory were associated with both RD and MD, reduced processing speed was related to RD, but not MD; and the association with RD was restricted to processing speed for familiar nameable symbols. In contrast, impairments in temporal processing and visuospatial memory were associated with MD, but not RD. PMID:25124507

  9. Encoding and Retrieving Faces and Places: Distinguishing Process- and Stimulus-Specific Differences in Brain Activity

    PubMed Central

    Prince, Steven E.; Dennis, Nancy A.; Cabeza, Roberto

    2009-01-01

    Among the most fundamental issues in cognitive neuroscience is how the brain may be organized into process-specific and stimulus-specific regions. In the episodic memory domain, most functional neuroimaging studies have focused on the former dimension, typically investigating the neural correlates of various memory processes. Thus, there is little information about what role stimulus-specific brain regions play in successful memory processes. To address this issue, the present event-related fMRI study used a factorial design to focus on the role of stimulus-specific brain regions, such as the fusiform face area (FFA) and parahippocampal place area (PPA) in successful encoding and retrieval processes. Searching within regions sensitive to faces or places, we identified areas similarly involved in encoding and retrieval, as well as areas differentially involved in encoding or retrieval. Finally, we isolated regions associated with successful memory, regardless of stimulus and process type. There were three main findings. Within face sensitive regions, anterior medial PFC and right FFA displayed equivalent encoding and retrieval success processes whereas left FFA was associated with successful encoding rather than retrieval. Within place sensitive regions, left PPA displayed equivalent encoding and retrieval success processes whereas right PPA was associated with successful encoding rather than retrieval. Finally, medial temporal and prefrontal regions were associated with general memory success, regardless of stimulus or process type. Taken together, our results clarify the contribution of different brain regions to stimulus- and process-specific episodic memory mechanisms. PMID:19524092

  10. Dyslexia and Specific Language Impairment: The Role of Phonology and Auditory Processing

    ERIC Educational Resources Information Center

    Fraser, Jill; Goswami, Usha; Conti-Ramsden, Gina

    2010-01-01

    We explore potential similarities between developmental dyslexia (specific reading disability [SRD]) and specific language impairment (SLI) in terms of phonological skills, underlying auditory processing abilities, and nonphonological language skills. Children aged 9 to 11 years with reading and/or language difficulties were recruited and compared…

  11. Look but Don't Touch: Tactile Disadvantage in Processing Modality-Specific Words

    ERIC Educational Resources Information Center

    Connell, Louise; Lynott, Dermot

    2010-01-01

    Recent neuroimaging research has shown that perceptual and conceptual processing share a common, modality-specific neural substrate, while work on modality switching costs suggests that they share some of the same attentional mechanisms. In three experiments, we employed a modality detection task that displayed modality-specific object properties…

  12. Wire-reinforced, light-cured glass ionomer-resin provisional restoration: a description of the technical procedure.

    PubMed

    Liebenberg, W H

    1994-09-01

    A procedure to use round-wire and glass ionomer-resin cement to make practical provisional restorations is presented. The viability of the use of glass ionomer-resin cement and the need for embrasure perfection in provisional restorations is discussed. This procedure is suitable as a long-term provisional restoration where extensive coronal destruction has occurred. The inherent disadvantage of the procedure is the need to involve occlusal surfaces of the proximal teeth; thus its use is restricted to mouths in which the adjacent teeth are to receive simultaneous restorative treatment. PMID:7965911

  13. Win some, lose some: hypermnesia for actions reflects increased item-specific processing.

    PubMed

    Olofsson, U

    1997-11-01

    Memory for simple action phrases (e.g., "Break a match") improves when subjects perform the actions at study. The relative contribution of item-specific and relational processing to this enactment effect has been an issue of considerable debate. It was addressed in the present study by examining hypermnesia in a multiple-test free recall paradigm, based on the assumptions that item-specific processing increases the probability of interest gains and relational processing protects against interest forgetting (e.g., Burns, 1993; Klein, Loftus, Kihlstrom, & Aseron, 1989). It was found that the enactment condition produced both significantly more gains and more losses than did the nonenactment condition, resulting in a net gain (hypermnesia) for the enactment condition. The results suggest that enactment promotes item-specific processing at the expense of relational processing. PMID:9421565

  14. Modality-specific processing precedes amodal linguistic processing during L2 sign language acquisition: A longitudinal study.

    PubMed

    Williams, Joshua T; Darcy, Isabelle; Newman, Sharlene D

    2016-02-01

    The present study tracked activation pattern differences in response to sign language processing by late hearing second language learners of American Sign Language. Learners were scanned before the start of their language courses. They were scanned again after their first semester of instruction and their second, for a total of 10 months of instruction. The study aimed to characterize modality-specific to modality-general processing throughout the acquisition of sign language. Results indicated that before the acquisition of sign language, neural substrates related to modality-specific processing were present. After approximately 45 h of instruction, the learners transitioned into processing signs on a phonological basis (e.g., supramarginal gyrus, putamen). After one more semester of input, learners transitioned once more to a lexico-semantic processing stage (e.g., left inferior frontal gyrus) at which language control mechanisms (e.g., left caudate, cingulate gyrus) were activated. During these transitional steps right hemispheric recruitment was observed, with increasing left-lateralization, which is similar to other native signers and L2 learners of spoken language; however, specialization for sign language processing with activation in the inferior parietal lobule (i.e., angular gyrus), even for late learners, was observed. As such, the present study is the first to track L2 acquisition of sign language learners in order to characterize modality-independent and modality-specific mechanisms for bilingual language processing. PMID:26720258

  15. 42 CFR 457.1140 - Program specific review process: Core elements of review.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Program specific review process: Core elements of review. 457.1140 Section 457.1140 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF... review process: Core elements of review. In adopting the procedures for review of matters described...

  16. Real-Time Language Processing in School-Age Children with Specific Language Impairment

    ERIC Educational Resources Information Center

    Montgomery, James W.

    2006-01-01

    Background:School-age children with specific language impairment (SLI) exhibit slower real-time (i.e. immediate) language processing relative to same-age peers and younger, language-matched peers. Results of the few studies that have been done seem to indicate that the slower language processing of children with SLI is due to inefficient…

  17. Electrophysiological Correlates of Rapid Auditory and Linguistic Processing in Adolescents with Specific Language Impairment

    ERIC Educational Resources Information Center

    Weber-Fox, Christine; Leonard, Laurence B.; Wray, Amanda Hampton; Tomblin, J. Bruce

    2010-01-01

    Brief tonal stimuli and spoken sentences were utilized to examine whether adolescents (aged 14;3-18;1) with specific language impairments (SLI) exhibit atypical neural activity for rapid auditory processing of non-linguistic stimuli and linguistic processing of verb-agreement and semantic constraints. Further, we examined whether the behavioral…

  18. 42 CFR 457.1140 - Program specific review process: Core elements of review.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Program specific review process: Core elements of review. 457.1140 Section 457.1140 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF... review process: Core elements of review. In adopting the procedures for review of matters described...

  19. 42 CFR 457.1150 - Program specific review process: Impartial review.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Program specific review process: Impartial review... review process: Impartial review. (a) Eligibility or enrollment matter. The review of a matter described... matter under review. (b) Health services matter. The State must ensure that an enrollee has...

  20. 42 CFR 457.1150 - Program specific review process: Impartial review.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Program specific review process: Impartial review... review process: Impartial review. (a) Eligibility or enrollment matter. The review of a matter described... matter under review. (b) Health services matter. The State must ensure that an enrollee has...

  1. 42 CFR 457.1150 - Program specific review process: Impartial review.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Program specific review process: Impartial review... review process: Impartial review. (a) Eligibility or enrollment matter. The review of a matter described... matter under review. (b) Health services matter. The State must ensure that an enrollee has...

  2. 42 CFR 457.1150 - Program specific review process: Impartial review.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Program specific review process: Impartial review... review process: Impartial review. (a) Eligibility or enrollment matter. The review of a matter described... matter under review. (b) Health services matter. The State must ensure that an enrollee has...

  3. 42 CFR 457.1150 - Program specific review process: Impartial review.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Program specific review process: Impartial review... review process: Impartial review. (a) Eligibility or enrollment matter. The review of a matter described... matter under review. (b) Health services matter. The State must ensure that an enrollee has...

  4. Evidence for Reduced Domain-Specificity in Auditory Processing in Autism

    ERIC Educational Resources Information Center

    Jarvinen-Pasley, Anna; Heaton, Pamela

    2007-01-01

    Neurological and behavioral findings indicate that atypical auditory processing characterizes autism. The present study tested the hypothesis that auditory processing is less domain-specific in autism than in typical development. Participants with autism and controls completed a pitch sequence discrimination task in which same/different judgments…

  5. Visuo-Spatial Processing and Executive Functions in Children with Specific Language Impairment

    ERIC Educational Resources Information Center

    Marton, Klara

    2008-01-01

    Background: Individual differences in complex working memory tasks reflect simultaneous processing, executive functions, and attention control. Children with specific language impairment (SLI) show a deficit in verbal working memory tasks that involve simultaneous processing of information. Aims: The purpose of the study was to examine executive…

  6. On the nature of bias and defects in the software specification process

    NASA Technical Reports Server (NTRS)

    Straub, Pablo A.; Zelkowitz, Marvin V.

    1992-01-01

    Implementation bias in a specification is an arbitrary constraint in the solution space. This paper describes the problem of bias. Additionally, this paper presents a model of the specification and design processes describing individual subprocesses in terms of precision/detail diagrams and a model of bias in multi-attribute software specifications. While studying how bias is introduced into a specification we realized that software defects and bias are dual problems of a single phenomenon. This was used to explain the large proportion of faults found during the coding phase at the Software Engineering Laboratory at NASA/GSFC.

  7. An Investigation Into the Integrity of Fit of Provisional Crowns Using Current Proprietary Temporary Crown Materials.

    PubMed

    Taylor, Philip D; Georgakis, Georgios; Niggli, Jason

    2016-06-01

    Three methods of direct provisional crown construction were investigated for accuracy of marginal fit. A modified proprietary crown coping was compared to Bis GMA and isobutyl methacrylate resin provisional crowns with margins modified by using a flowable composite and 'bead on' isobutyl methacrylate respectively. Measurement was at 50x magnification at seven sites over the fit surface. Data was analyzed using SPSS version 13.0.1 and measurement compared using the Mann Whitney test set at a significance level of 0.05. Reliability was checked using the Bland Altman test. Statistical significant differences were found between the three groups. The order of best fit was Bis-GMA and flowable composite > isobutyl methacrylate with 'bead on' margins > Bis-GMA modified implant temporary coping. The clinical significance is that the Bis GMA and flowable composite combination can be used with equal confidence to traditional methods of temporarisation. PMID:27424335

  8. Towards an Australian Bioregionalisation Atlas: A provisional area taxonomy of Australia's biogeographical regions.

    PubMed

    Ebach, Malte C; Gillu, Anthony C; Kwan, Alan; Ahyong, Shane T; Murphy, Daniel J; Cassis, Gerasimos

    2013-01-01

    The large number, definition, varied application and validity of named Australian biogeographical regions reflect their ad hoc development via disparate methods or case study idiosyncracies. They do not represent a coherent system. In order to resolve these uncertainties an Australian Bioregionalisation Atlas is proposed as a provisional hierarchical classification, accounting for all known named areas. This provisional area taxonomy includes a diagnosis, description, type locality and map for each named area within the Australian continent, as well as a first-ever area synonymy. Akin to biological classifications, this Atlas seeks to provision universality, objectivity and stability, such that biogeographers, macroecologists and geographers, can test existing areas as well as proposing novel areas. With such a formalised and comparative system in place, practitioners can analyse the definition and relationships of biotic areas, and putatively minimise ad hoc explanations. PMID:26131478

  9. Provisional pin fixation can maintain reduction in A3 intertrochanteric fractures.

    PubMed

    Cho, Jae-Woo; Kim, Hyung-Jin; Kim, Jinil; Cho, Won-Tae; Jeong, Chan-Dong; Oh, Jong-Keon

    2016-07-01

    A3 intertrochanteric fracture has a higher incidence of intraoperative re-displacement than A1 and 2. The authors have also experienced difficulty with maintenance of reduction in A3 intertrochanteric fractures, as the technique depends on manual effort and can fail easily during the procedure. It induced us to develop this surgical technique to ease the surgical procedure and improve clinical outcomes. This paper introduces a modified provisional guide pin fixation technique applicable to even AO/OTA A3 intertrochanteric fractures, and presents preliminary results of 11 patients who were treated by provisional pin fixation-assisted nailing in A3 intertrochanteric fractures. Using this technique, we have reduced the chances of intraoperative reduction loss and achieved favorable clinical outcomes. PMID:27245452

  10. Shear bond strength of provisional restoration materials repaired with light-cured resins.

    PubMed

    Chen, Hsiu-Lin; Lai, Yu-lin; Chou, I-chiang; Hu, Chiung-Jen; Lee, Shyh-yuan

    2008-01-01

    This study evaluated the repair bond strengths of light-cured resins to provisional restoration materials with different chemical compositions and polymerization techniques. Fifty discs (10 mm in diameter and 1.5 mm thick) were fabricated for each provisional resin base material, including a self-cured methacrylate (Alike), self-cured bis-acrylate (Protemp 3 Garant), light-cured bis-acrylate (Revotek LC) and a heat-cured methacrylate (Namilon). All specimens were stored in distilled water at 37 degrees C for seven days before undergoing repair with one of four light-cured resins, including AddOn, Revotek LC, Dyractflow and Unifast LC and a self-cured resin (Alike), according to the manufacturers' instructions, for a total of 200 specimens. After 24 hours of storage in 37 degrees C water, the shear bond strengths were measured with a universal testing machine and fracture surfaces were examined under a stereomicroscope. Two-way ANOVA revealed that provisional resin-base material (p < 0.001), repair material (p < 0.001) and their interactions (p < 0.001) significantly affected the repair strength. Tukey's multiple comparisons showed that the lowest bonding strengths were found in specimens of heat-cured methacrylate resin materials repaired with bis-acryl resins, with their failure modes primarily being of the adhesive type. The highest bond strengths were recorded when the provisional resin-base materials and repairing resins had similar chemical components and the failure modes tended to be of the cohesive type. PMID:18833857

  11. Immediate provisionalization of dental implants placed in fresh extraction sockets using a flapless technique.

    PubMed

    Crespi, Roberto; Capparè, Paolo; Gherlone, Enrico; Romanos, George

    2012-02-01

    The aim of this clinical study was to evaluate the 24-month clinical outcomes of immediate provisionalization of dental implants placed in fresh extraction sockets using a flapless technique. Fifteen patients were included under strict inclusion and exclusion criteria. All patients required one or two teeth to be extracted for lesions with a hopeless prognosis in the maxillary monoradicular or first premolar region. Twenty implants were placed immediately after tooth extraction, and immediate provisionalization was performed. Sixteen implants had a diameter of 5 mm, and four implants had a diameter of 3.80 mm, all with a 13-mm length. After 24 months of follow-up, a cumulative survival rate of 100% was reported for all implants. Modified Bleeding Index (mBI), modified Plaque Index (mPI), probing depth (PD), marginal gingiva level (MGL), and keratinized mucosa (KM) remained stable for up to 24 months. Mean MGL at 24 months was 0.22 ± 0.15 mm; no significant changes occurred in MGL between baseline and 24 months. Mean KM remained stable from baseline to 24 months. At 24 months, a mean bone loss of 0.83 ± 0.52 mm was measured. The results of this study indicate that flapless surgery for immediately provisionalized implants placed in fresh extraction sockets provides soft tissue and marginal bone maintenance for up to 24 months of follow-up. PMID:22254223

  12. Formal Specification and Automatic Analysis of Business Processes under Authorization Constraints: An Action-Based Approach

    NASA Astrophysics Data System (ADS)

    Armando, Alessandro; Giunchiglia, Enrico; Ponta, Serena Elisa

    We present an approach to the formal specification and automatic analysis of business processes under authorization constraints based on the action language \\cal{C}. The use of \\cal{C} allows for a natural and concise modeling of the business process and the associated security policy and for the automatic analysis of the resulting specification by using the Causal Calculator (CCALC). Our approach improves upon previous work by greatly simplifying the specification step while retaining the ability to perform a fully automatic analysis. To illustrate the effectiveness of the approach we describe its application to a version of a business process taken from the banking domain and use CCALC to determine resource allocation plans complying with the security policy.

  13. Cell-Specific Multifunctional Processing of Heterogeneous Cell Systems in a Single Laser Pulse Treatment

    PubMed Central

    Lukianova-Hleb, Ekaterina Y.; Mutonga, Martin B. G.; Lapotko, Dmitri O.

    2012-01-01

    Current methods of cell processing for gene and cell therapies use several separate procedures for gene transfer and cell separation or elimination, because no current technology can offer simultaneous multi-functional processing of specific cell sub-sets in highly heterogeneous cell systems. Using the cell-specific generation of plasmonic nanobubbles of different sizes around cell-targeted gold nanoshells and nanospheres, we achieved simultaneous multifunctional cell-specific processing in a rapid single 70 ps laser pulse bulk treatment of heterogeneous cell suspension. This method supported the detection of cells, delivery of external molecular cargo to one type of cells and the concomitant destruction of another type of cells without damaging other cells in suspension, and real-time guidance of the two above cellular effects. PMID:23167546

  14. Collaborative business process support in eHealth: integrating IHE profiles through ebXML business process specification language.

    PubMed

    Dogac, Asuman; Kabak, Yildiray; Namli, Tuncay; Okcan, Alper

    2008-11-01

    Integrating healthcare enterprise (IHE) specifies integration profiles describing selected real world use cases to facilitate the interoperability of healthcare information resources. While realizing a complex real-world scenario, IHE profiles are combined by grouping the related IHE actors. Grouping IHE actors implies that the associated business processes (IHE profiles) that the actors are involved must be combined, that is, the choreography of the resulting collaborative business process must be determined by deciding on the execution sequence of transactions coming from different profiles. There are many IHE profiles and each user or vendor may support a different set of IHE profiles that fits to its business need. However, determining the precedence of all the involved transactions manually for each possible combination of the profiles is a very tedious task. In this paper, we describe how to obtain the overall business process automatically when IHE actors are grouped. For this purpose, we represent the IHE profiles through a standard, machine-processable language, namely, Organization for the Advancement of Structured Information Standards (OASIS) ebusiness eXtensible Markup Language (ebXML) Business Process Specification (ebBP) Language. We define the precedence rules among the transactions of the IHE profiles, again, in a machine-processable way. Then, through a graphical tool, we allow users to select the actors to be grouped and automatically produce the overall business process in a machine-processable format. PMID:19000955

  15. Brainstem Correlates of Temporal Auditory Processing in Children with Specific Language Impairment

    ERIC Educational Resources Information Center

    Basu, Madhavi; Krishnan, Ananthanarayan; Weber-Fox, Christine

    2010-01-01

    Deficits in identification and discrimination of sounds with short inter-stimulus intervals or short formant transitions in children with specific language impairment (SLI) have been taken to reflect an underlying temporal auditory processing deficit. Using the sustained frequency following response (FFR) and the onset auditory brainstem responses…

  16. Specific and Nonspecific Neural Activity during Selective Processing of Visual Representations in Working Memory

    ERIC Educational Resources Information Center

    Oh, Hwamee; Leung, Hoi-Chung

    2010-01-01

    In this fMRI study, we investigated prefrontal cortex (PFC) and visual association regions during selective information processing. We recorded behavioral responses and neural activity during a delayed recognition task with a cue presented during the delay period. A specific cue ("Face" or "Scene") was used to indicate which one of the two…

  17. 50 CFR 648.96 - FMP review, specification, and framework adjustment process.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ABCs and ACLs for the upcoming fishing year(s) as described in paragraph (c) of this section. (ii) The..., including specification of ABC and ACLs, if necessary. (2) Councils' recommendation. After developing... in writing of the reasons for the non-concurrence. (c) Process for setting ABCs and ACLs. (1)...

  18. 50 CFR 648.96 - FMP review, specification, and framework adjustment process.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ABCs and ACLs for the upcoming fishing year(s) as described in paragraph (c) of this section. (ii) The...)(i) of this section, including specification of ABC and ACLs, if necessary. (2) Councils... Councils shall be notified in writing of the reasons for the non-concurrence. (c) Process for setting...

  19. 50 CFR 648.96 - FMP review, specification, and framework adjustment process.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ABCs and ACLs for the upcoming fishing year(s) as described in paragraph (c) of this section. (ii) The...)(i) of this section, including specification of ABC and ACLs, if necessary. (2) Councils... Councils shall be notified in writing of the reasons for the non-concurrence. (c) Process for setting...

  20. Gene recovery microdissection (GRM) a process for producing chromosome region-specific libraries of expressed genes

    SciTech Connect

    Christian, A T; Coleman, M A; Tucker, J D

    2001-02-08

    Gene Recovery Microdissection (GRM) is a unique and cost-effective process for producing chromosome region-specific libraries of expressed genes. It accelerates the pace, reduces the cost, and extends the capabilities of functional genomic research, the means by which scientists will put to life-saving, life-enhancing use their knowledge of any plant or animal genome.

  1. Behavioral Profiles Associated with Auditory Processing Disorder and Specific Language Impairment

    ERIC Educational Resources Information Center

    Miller, Carol A.; Wagstaff, David A.

    2011-01-01

    Purpose: To describe and compare behavioral profiles associated with auditory processing disorder (APD) and specific language impairment (SLI) in school-age children. Method: The participants in this cross-sectional observational study were 64 children (mean age 10.1 years) recruited through clinician referrals. Thirty-five participants had a…

  2. Children with specific language impairment also show impairment of music-syntactic processing.

    PubMed

    Jentschke, Sebastian; Koelsch, Stefan; Sallat, Stephan; Friederici, Angela D

    2008-11-01

    Both language and music consist of sequences that are structured according to syntactic regularities. We used two specific event-related brain potential (ERP) components to investigate music-syntactic processing in children: the ERAN (early right anterior negativity) and the N5. The neural resources underlying these processes have been posited to overlap with those involved in the processing of linguistic syntax. Thus, we expected children with specific language impairment (SLI, which is characterized by deficient processing of linguistic syntax) to demonstrate difficulties with music-syntactic processing. Such difficulties were indeed observed in the neural correlates of music-syntactic processing: neither an ERAN nor an N5 was elicited in children with SLI, whereas both components were evoked in age-matched control children with typical language development. Moreover, the amplitudes of ERAN and N5 were correlated with subtests of a language development test. These data provide evidence for a strong interrelation between the language and the music processing system, thereby setting the ground for possible effects of musical training in SLI therapy. PMID:18416683

  3. Electrophysiological Correlates of Rapid Auditory and Linguistic Processing in Adolescents with Specific Language Impairment

    PubMed Central

    Weber-Fox, Christine; Leonard, Laurence B.; Wray, Amanda Hampton; Tomblin, J. Bruce

    2010-01-01

    Brief tonal stimuli and spoken sentences were utilized to examine whether adolescents (aged 14;3-18;1) with specific language impairments (SLI) exhibit atypical neural activity for rapid auditory processing of non-linguistic stimuli and linguistic processing of verb-agreement and semantic constraints. Further, we examined whether the behavioral and electrophysiological indices for rapid auditory processing were correlated with those for linguistic processing. Fifteen adolescents with SLI and 15 adolescents with normal language met strict criteria for displaying consistent diagnoses from kindergarten through the eighth grade. The findings provide evidence that auditory processing for non-linguistic stimuli is atypical in a significant number of adolescents with SLI compared to peers with normal language and indicate that reduced efficiency in auditory processing in SLI is more vulnerable to rapid rates (200 ms ISI) of stimuli presentation (indexed by reduced accuracy, a tendency for longer RTs, reduced N100 over right anterior sites, and reduced amplitude P300). Many adolescents with SLI displayed reduced behavioral accuracy for detecting verb-agreement violations and semantic anomalies, along with less robust P600s elicited by verb-agreement violations. The results indicate that ERPs elicited by morphosyntactic aspects of language processing are atypical in many adolescents with SLI. Additionally, correlational analyses between behavioral and electrophysiological indices of processing non-linguistic stimuli and verb-agreement violations suggest that the integrity of neural functions for auditory processing may only account for a small proportion of the variance in morphosyntactic processing in some adolescents. PMID:20889197

  4. Randomized trial on routine vs. provisional T-stenting in the treatment of de novo coronary bifurcation lesions

    PubMed Central

    Ferenc, Miroslaw; Gick, Michael; Kienzle, Rolf-Peter; Bestehorn, Hans-Peter; Werner, Klaus-Dieter; Comberg, Thomas; Kuebler, Piotr; Büttner, Heinz Joachim; Neumann, Franz-Josef

    2008-01-01

    Aims We investigated whether routine T-stenting reduces restenosis of the side branch as compared with provisional T-stenting in patients with de novo coronary bifurcation lesions. Methods and results Our randomized study assigned 101 patients with a coronary bifurcation lesion to routine T-stenting with sirolimus-eluting stents (SES) in both branches and 101 patients to provisional T-stenting with SES placement in the main branch followed by kissing-balloon angioplasty and provisional SES placement in the side branch only for inadequate results. Primary endpoint was per cent diameter stenosis of the side branch at 9 month angiographic follow-up. Angiographic follow-up in 192 (95%) patients revealed a per cent stenosis of the side branch of 23.0 ± 20.2% after provisional T-stenting (19% with side-branch stent) and of 27.7 ± 24.8% (P = 0.15) after routine T-stenting (98.2% with side-branch stent). The corresponding binary restenosis rates were 9.4 and 12.5% (P = 0.32), prompting re-intervention in 5.0 and 7.9% (P = 0.39), respectively. In the main branch, binary restenosis rates were 7.3% after provisional and 3.1% after routine T-stenting (P = 0.17). The overall 1 year incidence of target lesion re-intervention was 10.9% after provisional and 8.9% after routine T-stenting (P = 0.64). Conclusions Routine T-stenting with SES did not improve the angiographic outcome of percutaneous coronary intervention of coronary bifurcation lesions as compared with stenting of the main branch followed by kissing-balloon angioplasty and provisional side-branch stenting. PMID:18845665

  5. A Compilation of Provisional Karst Geospatial Data for the Interior Low Plateaus Physiographic Region, Central United States

    USGS Publications Warehouse

    Taylor, Charles J.; Nelson, Hugh L.

    2008-01-01

    Geospatial data needed to visualize and evaluate the hydrogeologic framework and distribution of karst features in the Interior Low Plateaus physiographic region of the central United States were compiled during 2004-2007 as part of the Ground-Water Resources Program Karst Hydrology Initiative (KHI) project. Because of the potential usefulness to environmental and water-resources regulators, private consultants, academic researchers, and others, the geospatial data files created during the KHI project are being made available to the public as a provisional regional karst dataset. To enhance accessibility and visualization, the geospatial data files have been compiled as ESRI ArcReader data folders and user interactive Published Map Files (.pmf files), all of which are catalogued by the boundaries of surface watersheds using U.S. Geological Survey (USGS) eight-digit hydrologic unit codes (HUC-8s). Specific karst features included in the dataset include mapped sinkhole locations, sinking (or disappearing) streams, internally drained catchments, karst springs inventoried in the USGS National Water Information System (NWIS) database, relic stream valleys, and karst flow paths obtained from results of previously reported water-tracer tests.

  6. Critical Role of Autophagy in the Processing of Adenovirus Capsid-Incorporated Cancer-Specific Antigens

    PubMed Central

    Klein, Sarah R.; Jiang, Hong; Hossain, Mohammad B.; Fan, Xuejun; Gumin, Joy; Dong, Andrew; Alonso, Marta M.; Gomez-Manzano, Candelaria; Fueyo, Juan

    2016-01-01

    Adenoviruses are highly immunogenic and are being examined as potential vectors for immunotherapy. Infection by oncolytic adenovirus is followed by massive autophagy in cancer cells. Here, we hypothesize that autophagy regulates the processing of adenoviral proteins for antigen presentation. To test this hypothesis, we first examined the presentation of viral antigens by infected cells using an antibody cocktail of viral capsid proteins. We found that viral antigens were processed by JNK-mediated autophagy, and that autophagy was required for their presentation. Consistent with these results, splenocytes isolated from virus-immunized mice were activated by infected cells in an MHC II-dependent manner. We then hypothesize that this mechanism can be utilized to generate an efficient cancer vaccine. To this end, we constructed an oncolytic virus encompassing an EGFRvIII cancer-specific epitope in the adenoviral fiber. Infection of cancer cells with this fiber-modified adenovirus resulted in recognition of infected cancer cells by a specific anti-EGFRvIII antibody. However, inhibition of autophagy drastically decreased the capability of the specific antibody to detect the cancer-related epitope in infected cells. Our data suggest that combination of adenoviruses with autophagy inducers may enhance the processing and presentation of cancer-specific antigens incorporated into capsid proteins. PMID:27093696

  7. Specific detection of banana residue in processed foods using polymerase chain reaction.

    PubMed

    Sakai, Yumiko; Ishihata, Kimie; Nakano, Shigeru; Yamada, Toshihiro; Yano, Takeo; Uchida, Kouji; Nakao, Yoshiki; Urisu, Atsuo; Adachi, Reiko; Teshima, Reiko; Akiyama, Hiroshi

    2010-07-28

    Specific polymerase chain reaction (PCR) methods were developed for the detection of banana residue in processed foods. For high banana specificity, the primer set BAN-F/BAN-R was designed on the basis of the large subunit of ribulose-1,5-bisphosphate carboxylase (rbcL) genes of chloroplasts and used to obtain amplified products specific to banana by both conventional and real-time PCR. To confirm the specificity of these methods, genomic DNA samples from 31 other species were examined; no amplification products were detected. Subsequently, eight kinds of processed foods containing banana were investigated using these methods to confirm the presence of banana DNA. Conventional PCR had a detection limit of 1 ppm (w/w) banana DNA spiked in 50 ng of salmon testis DNA, whereas SYBR Green I real-time semiquantitative PCR had a detection limit as low as 10 ppm banana DNA. Thus, both methods show high sensitivity and may be applicable as specific tools for the detection of trace amounts of banana in commercial food products. PMID:20604506

  8. Effects of Current Provisional Restoration Materials on the Viability of Fibroblasts

    PubMed Central

    Ulker, Mustafa; Ulker, H. Esra; Zortuk, Mustafa; Bulbul, Mehmet; Tuncdemir, Ali Riza; Bilgin, M. Selim

    2009-01-01

    Objectives: The aim of the present study was to evaluate the cytotoxic effects of three different provisional restoration materials on fibroblasts. Two bis-acrylic based [Tempofit Duomix (Detax), Protemp 3 Garant (3M ESPE)] and one urethan dimethacrylate [Revotek LC (GC Corporation)] based provisional restoration materials used. Methods: Materials were prepared according to the manufacturers’ instructions in standard teflon disks (2×5 mm) and four samples were extracted in 7 ml of Basal Medium Eagle with 10% new born calf serum and 100 mg/ml penicillin/streptomycin for 24 hours. The L929 fibroblast cells were plated (25.000 cells/ml) in well plates, and maintained in a CO2 incubator at 37°C for 24h. After 24 hours, the incubation medium was replaced by the immersed medium in which the samples were stored and the L929 fibroblasts were incubated in contact with eluates for 24 hours at 37°C for 24h. The fibroblast cell viability was analyzed by measuring the mitochondrial activity with the methyltetrazolium test (MTT). Twelve well used for each specimen and experiment repeated for two times. The data was statistically analyzed by Mann-Whitney U tests. Results: The results showed that, Revotek LC and Protemp 3 Garant were not cytotoxic for fibroblast cells when compared to control group (P>.05). However, Tempofit duomix was cytotoxic for L929 fibroblasts when compared to control group and other tested materials (P<.05). Conclusions: Taking into consideration the limitations of an in vitro study, our study indicate that provisional restoration materials might have cytotoxic effects on fibroblasts and should be selected carefully for clinical applications. PMID:19421391

  9. Comparative in vitro evaluation of CAD/CAM vs conventional provisional crowns

    PubMed Central

    ABDULLAH, Adil Othman; TSITROU, Effrosyni A; POLLINGTON, Sarah

    2016-01-01

    ABSTRACT Objective This study compared the marginal gap, internal fit, fracture strength, and mode of fracture of CAD/CAM provisional crowns with that of direct provisional crowns. Material and Methods An upper right first premolar phantom tooth was prepared for full ceramic crown following tooth preparation guidelines. The materials tested were: VITA CAD-Temp®, Polyetheretherketone “PEEK”, Telio CAD-Temp, and Protemp™4 (control group). The crowns were divided into four groups (n=10), Group1: VITA CAD-Temp®, Group 2: PEEK, Group 3: Telio CAD-Temp, and Group 4: Protemp™4. Each crown was investigated for marginal and internal fit, fracture strength, and mode of fracture. Statistical analysis was performed using GraphPad Prism software version 6.0. Results The average marginal gap was: VITA CAD-Temp® 60.61 (±9.99) µm, PEEK 46.75 (±8.26) µm, Telio CAD-Temp 56.10 (±5.65) µm, and Protemp™4 193.07(±35.96) µm (P<0.001). The average internal fit was: VITA CAD-Temp® 124.94 (±22.96) µm, PEEK 113.14 (±23.55) µm, Telio CAD-Temp 110.95 (±11.64) µm, and Protemp™4 143.48(±26.74) µm. The average fracture strength was: VITA CAD-Temp® 361.01 (±21.61) N, PEEK 802.23 (±111.29) N, Telio CAD-Temp 719.24 (±95.17) N, and Protemp™4 416.40 (±69.14) N. One-way ANOVA test showed a statistically significant difference for marginal gap, internal gap, and fracture strength between all groups (p<0.001). However, the mode of fracture showed no differences between the groups (p>0.05). Conclusions CAD/CAM fabricated provisional crowns demonstrated superior fit and better strength than direct provisional crowns. PMID:27383707

  10. Context Processing in Schizotypal Personality Disorder: Evidence of Specificity of Impairment to the Schizophrenia Spectrum

    PubMed Central

    McClure, Margaret M.; Flory, Janine D.; Barch, Deanna M.; Harvey, Philip D.; Siever, Larry J.

    2014-01-01

    Working memory abnormalities, which are particularly pronounced on context processing tasks, appear relatively specific to schizophrenia spectrum illnesses compared with other psychotic disorders. However, the specificity of context processing deficits to schizotypal personality disorder (SPD), a prototype of schizophrenia, has not been studied. The authors administered 3 versions of the modified AX Continuous Performance Test and an N-back working memory test to 63 individuals with SPD and 25 with other personality disorders, as well as 42 healthy controls. For the AX Continuous Performance Test standard and degraded versions, there was a significant Trial Type × Delay × Group interaction, as SPDs made significantly more errors reflecting poor maintenance of context and fewer errors reflecting good maintenance of context. SPDs also demonstrated poor performance on the N-back, especially at the 2-back condition. Context processing errors and N-back accuracy scores were related to disorganization symptoms. These findings, which are quite similar to those previously reported in patients with schizophrenia, suggest that context processing deficits are specific to the schizophrenia spectrum and are not a reflection of overall psychopathology. PMID:18489210

  11. Visual specificity effects on word stem completion: beyond transfer appropriate processing?

    PubMed

    Curran, T; Schacter, D L; Bessenoff, G

    1996-03-01

    An important, but poorly understood, aspect of memory retrieval concerns the conditions under which priming is influenced by perceptual changes in the form of target items. According to transfer appropriate processing perspectives, perceptual specificity effects on priming require a study task that focuses attention on the perceptual, rather than semantic, features of the items. Other research suggests that perceptual specificity effects are enhanced by conditions yielding high levels of explicit memory. The present experiments manipulated encoding tasks and other variables known to influence explicit memory (repetition and retention interval) in order to gain insight into the determinants of perceptual specificity effects on visual word-stem completion. In Experiment 1 we found that perceptual specificity (letter case) effects on stem completion priming depend on perceptual encoding when subjects' awareness of the study-test relationship is limited. In Experiments 2-4 we found that perceptual specificity effects can be obtained after semantic encoding--especially when the study-test retention interval is short. Perceptual specificity effects after short retention intervals were independent of encoding task, and may reflect a form of involuntary explicit memory. PMID:8653095

  12. Effect of different provisional cement remnant cleaning procedures including Er:YAG laser on shear bond strength of ceramics

    PubMed Central

    Zortuk, Mustafa; Gumus, Hasan Onder; Kilinc, Halil Ibrahim

    2012-01-01

    PURPOSE The purpose of this study was to evaluate the effect of provisional cement removal by different dentin cleaning protocols (dental explorer, pumice, cleaning bur, Er:YAG laser) on the shear bond strength between ceramic and dentin. MATERIALS AND METHODS In total, 36 caries-free unrestored human third molars were selected as tooth specimens. Provisional restorations were fabricated and cemented with eugenol-free provisional cement. Then, disc-shaped ceramic specimens were fabricated and randomly assigned to four groups of dentin cleaning protocols (n = 9). Group 1 (control): Provisional cements were mechanically removed with a dental explorer. Group 2: The dentin surfaces were treated with a cleaning brush with pumice Group 3: The dentin surfaces were treated with a cleaning bur. Group 4: The provisional cements were removed by an Er:YAG laser. Self-adhesive luting cement was used to bond ceramic discs to dentin surfaces. Shear bond strength (SBS) was measured using a universal testing machine at a 0.05 mm/min crosshead speed. The data were analyzed using a Kolmogorov Smirnov, One-way ANOVA and Tukey HSD tests to perform multiple comparisons (α=0.05). RESULTS The dentin cleaning methods did not significantly affect the SBS of ceramic discs to dentin as follows: dental explorer, pumice, cleaning bur, and Er:YAG laser. CONCLUSION The use of different cleaning protocols did not affect the SBS between dentin and ceramic surfaces. PMID:23236570

  13. Use of intraoral welding to stabilize dental implants in augmented sites for immediate provisionalization: a case report.

    PubMed

    Avvanzo, Pierluigi; Fabrocini, Lelio A; Ciavarella, Domenico; Avvanzo, Andrea; Lo Muzio, Lorenzo; De Maio, Raffaele A

    2012-02-01

    Immediate implant rehabilitation of edentulous arches may be somewhat problematic because of anatomic situations involving insufficient bone thickness or height and tooth position. The aim of this report was to present a retrospective case series of dental implants placed into augmented sites (split crest or sinus augmentation) that were stabilized with an intraorally welded framework at the time of immediate provisionalization. An intraoral welding unit was used to join and stabilize implants as an orthopedic splint to break down forces applied on provisional restorations during healing and osseointegration. This approach allows for the immediate provisionalization of implants in bone-defective areas where multiple implant systems have been enacted. Forty-eight implants in 16 patients were inserted, welded together to a titanium framework, and immediately provisionalized during the same surgery in which split-crest or sinus augmentation procedures were performed. After removing the welded frameworks, 1 of 48 implants failed; the failed implant was associated with a sinus augmentation procedure. Intraoral welding stabilization may be a predictable procedure to allow immediate loading in augmented areas during healing time and to stabilize implants against nonaxial forces, thereby reducing the number of surgical and prosthetic sessions and making patients comfortable and accustomed to immediate fixed provisional and definitive restorations. PMID:20932150

  14. Word stress processing in specific language impairment: auditory or representational deficits?

    PubMed

    Haake, Caroline; Kob, Malte; Willmes, Klaus; Domahs, Frank

    2013-08-01

    Word stress processing has repeatedly been reported to be affected in specific language impairment (SLI) with potential consequences for various aspects of language development. However, it still remains unresolved whether word stress impairments in SLI are due to deficits in basic auditory processing or to a degraded phonological representation or both. We addressed this question examining an unselected sample of 10 children with SLI and 11 typically developing (TD) children, aged about 8 years, with respect to their basic auditory processing (duration and skewness discrimination) and phonological representation of prosodic (word stress) and segmental (consonant) contrasts. Our results show lower performance of the SLI group compared to the TD group in all tasks. Crucially, two subgroups of children with SLI emerged from our analyses: While one group was impaired in basic auditory perception, particularly affecting duration discrimination, the other showed no significant auditory processing deficits but a representational impairment. PMID:23806129

  15. An Advanced User Interface Approach for Complex Parameter Study Process Specification in the Information Power Grid

    NASA Technical Reports Server (NTRS)

    Yarrow, Maurice; McCann, Karen M.; Biswas, Rupak; VanderWijngaart, Rob; Yan, Jerry C. (Technical Monitor)

    2000-01-01

    The creation of parameter study suites has recently become a more challenging problem as the parameter studies have now become multi-tiered and the computational environment has become a supercomputer grid. The parameter spaces are vast, the individual problem sizes are getting larger, and researchers are now seeking to combine several successive stages of parameterization and computation. Simultaneously, grid-based computing offers great resource opportunity but at the expense of great difficulty of use. We present an approach to this problem which stresses intuitive visual design tools for parameter study creation and complex process specification, and also offers programming-free access to grid-based supercomputer resources and process automation.

  16. NPRA Q and A - 1; 1990 Fuel specifications will require process changes

    SciTech Connect

    Yuan, D.C. ); Soumagne, G.; Siegrist, M.R. )

    1990-02-26

    This paper discusses the alteration of specifications for gasoline and diesel fuels in the 1990:0090s. Higher-octane gasoline with lower vapor pressure, and diesel fuel with lower sulfur and aromatics, will require process changes to produce. These altered fuel specifications prompted several questions at the most recent National Petroleum Refiners Association annual question and answer session on refining and petrochemical technology held in New Orleans, October 4-6, 1989. At this meeting, moderated by Herbert W. Bruch, NPRA's technical director, engineers and managers from refineries and petrochemical plants around the world gather to discuss their operating experiences in the form of questions and answers that cover a wide range of topics. A panel of selected technical representatives of operating companies and suppliers first answer previously submitted questions, then the audience is invited to add its contributions. This excerpt from the transcript of the meeting examines operating conditions and catalysts that increase motor octane number in FCC units, the effects on processes of lower vapor pressure gasoline specifications, and processing routes to low sulfur and aromatic diesel fuels.

  17. Finite element analysis of provisional structures of implant-supported complete prostheses.

    PubMed

    Carneiro, Bruno Albuquerque; de Brito, Rui Barbosa; França, Fabiana Mantovani Gomes

    2014-04-01

    The use of provisional resin implant-supported complete dentures is a fast and safe procedure to restore mastication and esthetics of patients soon after surgery and during the adaptation phase to the new denture. This study assessed stress distribution of provisional implant-supported fixed dentures and the all-on-4 concept using self-curing acrylic resin (Tempron) and bis-acrylic resin (Luxatemp) to simulate functional loads through the three-dimensional finite element method. Solidworks software was used to build three-dimensional models using acrylic resin (Tempron, model A) and bis-acrylic resin (Luxatemp, model B) for denture captions. Two loading patterns were applied on each model: (1) right unilateral axial loading of 150 N on the occlusal surfaces of posterior teeth and (2) oblique loading vector of 150 N at 45°. The results showed that higher stress was found on the bone crest below oblique load application with a maximum value of 187.57 MPa on model A and 167.45 MPa on model B. It was concluded that model B improved stress distribution on the denture compared with model A. PMID:24779949

  18. Global distribution of atmospheric carbon dioxide 2. A review of provisional background observations, 1978--1980

    SciTech Connect

    Fraser, P.J.; Pearman, G.I.; Hyson, P.

    1983-04-20

    An attempt is made to bring together provisional data collected throughout the world to construct a global picture of the background atmospheric carbon dioxide concentration distribution. The uncertainties, calibration and sampling difficulties, and measurement needs are discussed, and it is concluded that in general the accuracy of the provisional data at each sampling location is approx. +- 1 ppmv. Ongoing studies at the main laboratories are likely to significantly improve this accuracy in the near future. The most recent data available (for 1980) indicate annual average northern hemisphere high latitude CO/sub 2/ concentrations 4 to 5 ppmv above those at high latitudes of the southern hemisphere (approx.336 ppmv). The greatest uncertainty in the zonal average concentration exists in the latitude band 10--30 /sup 0/N where surface observations are 2--3 ppmv higher than those measured by continuous analysis at the Mauna Loa Observatory. There is generally good agreement between a model-generated and the observed annual mean global distributions. The seasonality of concentration is small in the southern hemisphere (approx.1--2 ppmv peak to peak) rising to approx.6 ppmv at 20 /sup 0/N and approx.15 ppmv at high latitudes of the northern hemisphere. The total global atmospheric CO/sub 2/ content, averaged through 1980, is estimated to have been 7.15 x 10/sup 14/ kg of carbon with a probable uncertainty of 0.5 to 1.0%.

  19. What's up? Emotion-specific activation of vertical space during language processing.

    PubMed

    Dudschig, Carolin; de la Vega, Irmgard; Kaup, Barbara

    2015-03-01

    The relationship between language processing and vertical space has been shown for various groups of words including valence words, implicit location words, and words referring to religious concepts. However, it remains unclear whether these are single phenomena or whether there is an underlying common mechanism. Here, we show that the evaluation of word valence interacts with motor responses in the vertical dimension, with positive (negative) evaluations facilitating upward (downward) responses. When valence evaluation was not required, implicit location words (e.g., bird, shoe) influenced motor responses whereas valence words (e.g., kiss, hate) did not. Importantly, a subset of specific emotional valence words that are commonly associated with particular bodily postures (e.g., proud→upright; sad→slouched) did automatically influence motor responses. Together, this suggests that while the vertical spatial dimension is not directly activated by word valence, it is activated when processing words referring to emotional states with stereotypical bodily-postures. These results provide strong evidence that the activation of spatial associations during language processing is experience-specific in nature and cannot be explained with reference to a general mapping between all valence words and space (i.e., all positive and negative words generally relate to spatial processing). These findings support the experiential view of language comprehension, suggesting that the automatic reactivation of bodily experiences is limited to word groups referring to emotions or entities directly associated with spatial experiences (e.g., posture or location in the world). PMID:25454886

  20. Abnormal, affect-specific modulatory effects on early auditory processing in schizophrenia: magnetoencephalographic evidence.

    PubMed

    Junghöfer, Markus; Bröckelmann, Ann-Kathrin; Küppers, Kerstin; Ohrmann, Patricia; Pedersen, Anya

    2015-02-01

    Abnormalities in the perception and identification of emotions have frequently been reported in schizophrenia. Hemodynamic neuroimaging studies found functional abnormalities in cortical and subcortical brain circuits that are involved in normal affective processing, but the temporal dynamics of abnormal emotion processing in schizophrenia remain largely elusive. To investigate this issue, we recorded early auditory evoked field components by means of whole-head magnetoencephalography that were in response to emotion-associated tones in seventeen patients with schizophrenia and in seventeen healthy, matched controls. Forty-two click-like tones (conditioned stimuli; CS) acquired differential emotional meaning through an affective associative learning procedure by pairing each CS three times with either pleasant, unpleasant or neutral auditory scenes. As expected, differential affect-specific modulation in patients vs. controls was evident, starting at the auditory N1m onset latency of approximately 70ms, extending to 230ms. While controls showed the expected enhanced processing of emotion associated CS, patients revealed an inverted pattern with reduced processing of arousal, when compared to neutral stimuli, in the right prefrontal cortex. The present finding suggests impairments in the prioritization of emotionally salient vs. non-salient stimuli in patients with schizophrenia. Dysfunction in higher cognitive processes and behavior in schizophrenia may therefore reflect dysfunction in fundamental, early emotion processing stages. PMID:25497223

  1. A comparison of retentive strength of implant cement depending on various methods of removing provisional cement from implant abutment

    PubMed Central

    Keum, Eun-Cheol

    2013-01-01

    PURPOSE This study evaluated the effectiveness of various methods for removing provisional cement from implant abutments, and what effect these methods have on the retention of prosthesis during the definitive cementation. MATERIALS AND METHODS Forty implant fixture analogues and abutments were embedded in resin blocks. Forty cast crowns were fabricated and divided into 4 groups each containing 10 implants. Group A was cemented directly with the definitive cement (Cem-Implant). The remainder were cemented with provisional cement (Temp-Bond NE), and classified according to the method for cleaning the abutments. Group B used a plastic curette and wet gauze, Group C used a rubber cup and pumice, and Group D used an airborne particle abrasion technique. The abutments were observed using a stereomicroscope after removing the provisional cement. The tensile bond strength was measured after the definitive cementation. Statistical analysis was performed using one-way analysis of variance test (α=.05). RESULTS Group B clearly showed provisional cement remaining, whereas the other groups showed almost no cement. Groups A and B showed a relatively smooth surface. More roughness was observed in Group C, and apparent roughness was noted in Group D. The tensile bond strength tests revealed Group D to have significantly the highest tensile bond strength followed in order by Groups C, A and B. CONCLUSION A plastic curette and wet gauze alone cannot effectively remove the residual provisional cement on the abutment. The definitive retention increased when the abutments were treated with rubber cup/pumice or airborne particle abraded to remove the provisional cement. PMID:24049563

  2. Computational dissection of human episodic memory reveals mental process-specific genetic profiles

    PubMed Central

    Luksys, Gediminas; Fastenrath, Matthias; Coynel, David; Freytag, Virginie; Gschwind, Leo; Heck, Angela; Jessen, Frank; Maier, Wolfgang; Milnik, Annette; Riedel-Heller, Steffi G.; Scherer, Martin; Spalek, Klara; Vogler, Christian; Wagner, Michael; Wolfsgruber, Steffen; Papassotiropoulos, Andreas; de Quervain, Dominique J.-F.

    2015-01-01

    Episodic memory performance is the result of distinct mental processes, such as learning, memory maintenance, and emotional modulation of memory strength. Such processes can be effectively dissociated using computational models. Here we performed gene set enrichment analyses of model parameters estimated from the episodic memory performance of 1,765 healthy young adults. We report robust and replicated associations of the amine compound SLC (solute-carrier) transporters gene set with the learning rate, of the collagen formation and transmembrane receptor protein tyrosine kinase activity gene sets with the modulation of memory strength by negative emotional arousal, and of the L1 cell adhesion molecule (L1CAM) interactions gene set with the repetition-based memory improvement. Furthermore, in a large functional MRI sample of 795 subjects we found that the association between L1CAM interactions and memory maintenance revealed large clusters of differences in brain activity in frontal cortical areas. Our findings provide converging evidence that distinct genetic profiles underlie specific mental processes of human episodic memory. They also provide empirical support to previous theoretical and neurobiological studies linking specific neuromodulators to the learning rate and linking neural cell adhesion molecules to memory maintenance. Furthermore, our study suggests additional memory-related genetic pathways, which may contribute to a better understanding of the neurobiology of human memory. PMID:26261317

  3. Earth Observatory Satellite system definition study. Report 5: System design and specifications. Volume 6: Specification for EOS Central Data Processing Facility (CDPF)

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The specifications and functions of the Central Data Processing (CDPF) Facility which supports the Earth Observatory Satellite (EOS) are discussed. The CDPF will receive the EOS sensor data and spacecraft data through the Spaceflight Tracking and Data Network (STDN) and the Operations Control Center (OCC). The CDPF will process the data and produce high density digital tapes, computer compatible tapes, film and paper print images, and other data products. The specific aspects of data inputs and data processing are identified. A block diagram of the CDPF to show the data flow and interfaces of the subsystems is provided.

  4. Neurite-specific Ca2+ dynamics underlying sound processing in an auditory interneurone.

    PubMed

    Baden, T; Hedwig, B

    2007-01-01

    Concepts on neuronal signal processing and integration at a cellular and subcellular level are driven by recording techniques and model systems available. The cricket CNS with the omega-1-neurone (ON1) provides a model system for auditory pattern recognition and directional processing. Exploiting ON1's planar structure we simultaneously imaged free intracellular Ca(2+) at both input and output neurites and recorded the membrane potential in vivo during acoustic stimulation. In response to a single sound pulse the rate of Ca(2+) rise followed the onset spike rate of ON1, while the final Ca(2+) level depended on the mean spike rate. Ca(2+) rapidly increased in both dendritic and axonal arborizations and only gradually in the axon and the cell body. Ca(2+) levels were particularly high at the spike-generating zone. Through the activation of a Ca(2+)-sensitive K(+) current this may exhibit a specific control over the cell's electrical response properties. In all cellular compartments presentation of species-specific calling song caused distinct oscillations of the Ca(2+) level in the chirp rhythm, but not the faster syllable rhythm. The Ca(2+)-mediated hyperpolarization of ON1 suppressed background spike activity between chirps, acting as a noise filter. During directional auditory processing, the functional interaction of Ca(2+)-mediated inhibition and contralateral synaptic inhibition was demonstrated. Upon stimulation with different sound frequencies, the dendrites, but not the axonal arborizations, demonstrated a tonotopic response profile. This mirrored the dominance of the species-specific carrier frequency and resulted in spatial filtering of high frequency auditory inputs. PMID:17443773

  5. The process and results of departmental specific safety surveys for health care organizations. Successful program.

    PubMed

    Meittunen, E; Snyder, B; Meyer, M

    2001-04-01

    1. Meeting compliance and accreditation standards can be challenging for any organization, especially in the health care setting. Safety surveys can play a strategic role in proactively preparing for such events. 2. Implementing department specific safety surveys offers a tailored approach to monitoring and addressing the occupational safety issues that occur within each department. 3. Safety surveys are a method for assessing and monitoring the environment and employee training needs, and for driving safety decisions. 4. Safety in the workplace must be a shared and continuous responsibility among employees. A formal safety survey process instilling a culture of responsibility and "buy in" by all employees is necessary. PMID:11760523

  6. A computation using mutually exclusive processing is sufficient to identify specific Hedgehog signaling components

    PubMed Central

    Spratt, Spencer J.

    2013-01-01

    A system of more than one part can be deciphered by observing differences between the parts. A simple way to do this is by recording something absolute displaying a trait in one part and not in another: in other words, mutually exclusive computation. Conditional directed expression in vivo offers processing in more than one part of the system giving increased computation power for biological systems analysis. Here, I report the consideration of these aspects in the development of an in vivo screening assay that appears sufficient to identify components specific to a system. PMID:24391661

  7. 45 CFR 264.71 - What determines the amount of the provisional payment of contingency funds that will be made to a...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... payment of contingency funds that will be made to a State? 264.71 Section 264.71 Public Welfare... Requirements for the Contingency Fund? § 264.71 What determines the amount of the provisional payment of contingency funds that will be made to a State? We will make a provisional payment to a State that meets...

  8. Realization of high quality production schedules: Structuring quality factors via iteration of user specification processes

    NASA Technical Reports Server (NTRS)

    Hamazaki, Takashi

    1992-01-01

    This paper describes an architecture for realizing high quality production schedules. Although quality is one of the most important aspects of production scheduling, it is difficult, even for a user, to specify precisely. However, it is also true that the decision as to whether a scheduler is good or bad can only be made by the user. This paper proposes the following: (1) the quality of a schedule can be represented in the form of quality factors, i.e. constraints and objectives of the domain, and their structure; (2) quality factors and their structure can be used for decision making at local decision points during the scheduling process; and (3) that they can be defined via iteration of user specification processes.

  9. Functional specificity for high-level linguistic processing in the human brain

    PubMed Central

    Fedorenko, Evelina; Behr, Michael K.; Kanwisher, Nancy

    2011-01-01

    Neuroscientists have debated for centuries whether some regions of the human brain are selectively engaged in specific high-level mental functions or whether, instead, cognition is implemented in multifunctional brain regions. For the critical case of language, conflicting answers arise from the neuropsychological literature, which features striking dissociations between deficits in linguistic and nonlinguistic abilities, vs. the neuroimaging literature, which has argued for overlap between activations for linguistic and nonlinguistic processes, including arithmetic, domain general abilities like cognitive control, and music. Here, we use functional MRI to define classic language regions functionally in each subject individually and then examine the response of these regions to the nonlinguistic functions most commonly argued to engage these regions: arithmetic, working memory, cognitive control, and music. We find little or no response in language regions to these nonlinguistic functions. These data support a clear distinction between language and other cognitive processes, resolving the prior conflict between the neuropsychological and neuroimaging literatures. PMID:21885736

  10. [The emergence and institutionalization of sexology in Portugal: processes, actors, and specificities].

    PubMed

    Alarcão, Violeta; Machado, Fernando Luís; Giami, Alain

    2016-01-01

    Based on Bourdieu's field theory, this article analyzes the emergence and institutionalization of sexology as a science and profession in Portugal, identifying relevant institutions, actors, and professional practices and discussing its relations and specificities. The analysis begins by contextualizing the emergence of modern Western sexology in order to comprehend the Portuguese case in the international sexology context. The second section describes the social, cultural, and institutional factors that have driven the professionalization of sexology. The third section describes the emergence of Portuguese sexology and its principal historical milestones, institutions, and actors. Finally, the article discusses some implications of this process for the role of sexology as a science and profession. The study reveals the dynamics of national and international processes in the field, in the transition from a holistic perspective of sexology to the hegemony of sexual medicine, and sheds light on its mechanisms of legitimation as a transdisciplinary science of sexuality, suggesting future perspectives. PMID:27598015