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Venus - Ovda Regio  

NASA Technical Reports Server (NTRS)

This image covers much of Ovda Regio, which forms the western part of Aphrodite Terra. It covers an area about 2,250 kilometers (1,386 miles) wide by 1,300 kilometers (800 miles) north to south, and ranges in latitude from 8 degrees north to 12 degrees south and in longitude from 62 degrees east to 90 degrees east. Ovda Regio is a highland region that rises over 4 kilometers (2.5 miles) above the surrounding plain. Magellan images show a complex surface, with several generations of structures. A pervasive fabric of irregular broad domes and ridges and associated curvilinear valleys was flooded by lava, then fractured. The circular feature surrounded by dark lava flows in the western part of the image is a caldera, or large volcanic collapse pit. Late-stage extension created long graben, or fault-bounded valleys, is best seen near the center of the image. The northern boundary of Ovda Regio is a steep, curvilinear mountain belt made up of long, narrow, rounded ridges. These ridges are similar in appearance to folded mountain belts on Earth. Several impact craters, such as the circular features on the western margin of the image, are scattered across the area. The bright area in the southeast part of the image indicates the presence of a radar-reflective mineral such as pyrite. Most of the highland areas on Venus display a similar bright signal. Each pixel of this image covers an area on the surface 675 meters (2,215 feet) across, representing a 9- times reduction in resolution compared to full-scale resolution data.



Are the basins of Titan's Hotei Regio and Tui Regio sites of former low latitude seas?  

NASA Astrophysics Data System (ADS)

Features observed in the low-latitude basins of Hotei Regio and Tui Regio on Titan have attracted the attention of the Cassini-era investigators. At both locations, Visual Infrared Mapping Spectrometer (VIMS) observed isolated 5-?m bright ˜500 km wide features described as lobate in shape. Several studies have proposed that these materials are cryo-volcanic flows. We propose an alternative explanation. Recently published topographic profiles across Hotei Regio and Tui Regio indicate these features appear to occur in large regional basins, at least along the direction of the profiles. Cassini Synthetic Aperture Radar (SAR) images show that the terrains surrounding both topographically low-lying 5-?m bright features exhibit fluvial networks that appear to converge into the probable basins. The 5-?m bright features themselves correspond to fields of discrete radar-bright depressions whose bounding edges are commonly rounded and cumulate in planform in SAR images. These fields of discrete radar-bright depressions strongly resemble fields of features seen at Titan's high latitudes identified as dry lakes. Thus the combination of (1) the resemblance to high-latitude dry lakes, (2) location in the centers of regional depressions, and (3) convergence of fluvial networks are inferred by us to best explain the features of Hotei Regio and Tui Regio as sites of paleolake clusters (and perhaps former, now dry seas). These low-latitude paleolake clusters or former seas, if real, may be evidence of substantially larger inventories of liquid alkanes in Titan's past.

Moore, Jeffrey M.; Howard, Alan D.



Regio- and stereoselective aminopentadienylation of carbonyl compounds.  


A simple and robust protocol is detailed for the preparation of enantioenriched ?-substituted (1,4-pentadien-3-yl)amine derivatives. The methodology involves the addition of an in situ formed pentadienyl indium reagent to chiral tert-butylsulfinimines, previously formed in the same pot. The addition takes place with excellent ?-regio- and diastereoselectivity for a wide range of carbonyl compounds, including ?-unsubstituted aldehydes and methyl alkyl ketones. The catalytic hydrogenation of the sulfinamines obtained provides a convenient access to chiral ?-substituted (3-pentyl)amines. The hydroboration-oxidation of the ?-(1,4-pentadien-3-yl)amine derivatives, followed by a cyclization under Mitsunobu conditions, takes place with an excellent diastereoselectivity governed by the chiral sulfinyl group. PMID:24490803

Bosque, Irene; Bagdatli, Emine; Foubelo, Francisco; Gonzalez-Gomez, Jose C



Central Eistla Regio: Origin and relative age of topographic rise  

Microsoft Academic Search

Large topographic rises on Venus pose a number Of fundamental questions concerning the mantle processes responsible for them. Eistla Regio, a 7500 km-long elevated region extending WNW from the west end of Aphrodite Terra, is a particularly interesting example. The Sappho Patera quadrangle, 0-25øN, 0-30øE, includes all of central Eistla Regio, a region dominated by two interesting, apparently hybrid structures

George E. McGill



Efficient regio- and stereoselective access to novel fluorinated ?-aminocyclohexanecarboxylates  

PubMed Central

Summary A regio- and stereoselective method has been developed for the synthesis of novel fluorinated 2-aminocyclohexanecarboxylic acid derivatives with the fluorine attached to position 4 of the ring. The synthesis starts from either cis- or trans-?-aminocyclohex-4-enecarboxylic acids and involves regio- and stereoselective transformation of the ring C–C double bond through iodooxazine formation and hydroxylation, followed by hydroxy–fluorine or oxo–fluorine exchange. PMID:23843909

Kiss, Lorand; Nonn, Melinda; Sillanpaa, Reijo; Fustero, Santos



Regio- and stereoselective synthesis of new diaminocyclopentanols  

PubMed Central

Summary The optimal conditions for regio- and stereoselective epoxide ring opening of N,N-disubstituted 1,2-epoxy-3-aminocyclopentanes by different nucleophilic reagents have been developed. The substituents on the nitrogen atom in the epoxide precursor and the orientation of the oxirane ring are crucial for the reaction outcome. Thus, treatment of (1RS,2SR,3SR)-1,2-epoxy-3-(N,N-dibenzylamino)cyclopentane (3b) with amines gave a mixture of C1 and C2 regioadducts, while the use of (1RS,2SR,3SR)-1,2-epoxy-3-(N-benzyl-N-methylamino)cyclopentane (3a) led ultimately to C1 adducts. Base-catalyzed aminolysis of epoxides 6a,b afforded mainly C1 adducts 13a,b arising from trans-diaxal opening of the epoxide ring. Using a Lewis acid catalyst, epoxides 6a,b were transformed into diaminocyclopentanols 14a,b via an alternative pathway involving the formation of aziridinium intermediate 17. PMID:25383122

Kochubei, Valeri S; Atroshchenko, Yuri M



Venus - Volcanic Domes East of Beta Regio  

NASA Technical Reports Server (NTRS)

Two unusual volcanic domes are shown in this Magellan full-resolution mosaic. The image covers an area 180 by 240 kilometers (120 by 160 miles) centered at 18 degrees north latitude, 303.5 degrees east longitude, just east of Beta Regio. The dome in the south center of the image is about 45 kilometers (30 miles) across, with a 20 kilometer (13 mile) caldera, or volcanic collapse crater, in the center. The dome in the northwest corner of the image is about 30 kilometers (20 miles) across with a small (5 kilometer or 3 mile) summit crater. The very bright radar return from the western flank of this dome indicates that it has steep slopes. The flanks of the volcanoes display prominent gullies which may have been formed by slumping of surface material or thermal erosion by lava flows. Variations in the brightness with the surrounding plains show the extent of lava flows which originated at these volcanoes. Curved or bowed fractures surrounding the southern structure indicate that there has been subsidence, or sinking, of the dome following eruptive activity.



Geologic map of the Themis Regio quadrangle (V-53), Venus  

USGS Publications Warehouse

The Themis Regio quadrangle (V-53), Venus, has been geologically mapped at 1:5,000,000 scale as part of the NASA Planetary Geologic Mapping Program. The quadrangle extends from lat 25° to 50° S. and from long 270° to 300° E. and encompasses the Themis Regio highland, the surrounding plains, and the southernmost extension of Parga Chasmata. Themis Regio is a broad regional topographic high with a diameter of about 2,000 km and a height of about 0.5 km that has been interpreted previously as a hotspot underlain by a mantle plume. The Themis rise is dominated by coronae and lies at the terminus of the Parga Chasmata corona chain. Themis Regio is the only one of the three corona-dominated rises that contains significant extensional deformation. Fractures and grabens are much less common than along the rest of Parga Chasmata and are embayed by corona-related flows in places. Rift and corona formation has overlapped in time at Themis Regio.

Stofan, Ellen R.; Brian, Antony W.



Io - Full Disk Centered on Media Regio  

NASA Technical Reports Server (NTRS)

The mottled face of Jupiter's volcanically active moon Io [pronounced 'EYE-oh' or 'EE-OH'], viewed by the camera onboard NASA's Galileo spacecraft, shows dramatic changes since it was seen 17 years ago by the exploratory NASA spacecraft Voyagers 1 and 2. This Galileo image, taken on June 25, 1996 at a range of 2.24 million kilometers (1.4 million miles), is centered on the Media Regio area and shows details of the volcanic regions and colored deposits that characterize Io. North is at the top of the picture and the Sun illuminates the surface from the east (right). The smallest features that can be discerned here are approximately 23 kilometers (14 miles) in size, a resolution comparable to the best Voyager images of this face of Io. Io's surface is covered with volcanic deposits that are thought to contain ordinary silicate rock, along with various sulfur-rich compounds that give the satellite its distinctive color. In the brighter areas the surface is coated with frosts of sulfur dioxide. Dark areas are regions of current or recent volcanic activity. Planetary scientists say many changes are evident in the surface markings since this region of Io was imaged 17 years ago by the Voyager spacecraft. The bright regions near the eastern limb of the moon are much more prominent in the Galileo images than they were previously. Surface details have also changed dramatically in the vicinity of the eruptive volcano Masubi (the large, predominantly white feature seen near the 6 o'clock position in this view). Masubi was discovered as an active volcano during the Voyager encounters of Io in 1979.



Galileo Regio Mosaic - Galileo over Voyager Data  

NASA Technical Reports Server (NTRS)

A mosaic of four Galileo images of the Galileo Regio region on Ganymede (Latitude 18 N, Longitude: 149 W) is shown overlayed on the data obtained by the Voyager 2 spacecraft in 1979. North is to the top of the picture, and the sun illuminates the surface from the lower left, about 58 degrees above the horizon. The smallest features that can be discerned are about 80 meters (262 feet) in size in the Galileo images. These Galileo images show fine details of the dark terrain that makes up about half of the surface of the planet-sized moon. Ancient impact craters of various sizes and states of degradation testify to the great age of the terrain, dating back several billion years. The images reveal distinctive variations in albedo from the brighter rims, knobs, and furrow walls to a possible accumulation of dark material on the lower slopes, and crater floors. High photometric activity (large light contrast at high spatial frequencies) of this ice-rich surface was such that the Galileo camera's hardware data compressor was pushed into truncating lines. The north-south running gap between the left and right halves of the mosaic is a result of line truncation from the normal 800 samples per line to about 540. The images were taken on 27 June, 1996 Universal Time at a range of 7,580 kilometers (4,738 miles) through the clear filter of the Galileo spacecraft's imaging system. Launched in October 1989, Galileo entered orbit around Jupiter on December 7, 1995. The spacecraft's mission is to conduct detailed studies of the giant planet, its largest moons and the Jovian magnetic environment. The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.

This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL Background information and educational context for the images can be found at URL



Venus: Preliminary geologic mapping of northern Atla Regio  

NASA Technical Reports Server (NTRS)

A preliminary geologic map of C1 sheet 15N197 was compiled according to Magellan data. Northern Atla Regio is dominantly a volcanic plain with numerous volcanic features: radar-bright and -dark flows and spots, shield volcanos, volcanic domes and hills with varied morphology, and coronalike constructions. Tesserae are the oldest terrains semiflooded by plain materials. There are many lineated terrains on this territory. They are interpreted as old, partly buried ridge belts. Lineated terrains have intermediate age between young plains and old tesserae. Ozza Mons and Sapas Mons are the high shield volcanos. The prominent structure of northern Atla Regio is Ganis Chasma rift. The rift dissected the volcanic plain and evolved nearly contemporaneously with Ozza Mons shield volcano. Ganis Chasma rift valley is highly fractured and bounded by fault scarps. There are a few relatively young volcanic features in the rift valley. The rift originated due to 5-10 percent crustal extension and crustal subsidence according to analysis of fracturing and rift valley geometry. Ganis Chasma is characterized by rift shoulder uplifts. Geological structures of Alta Regio and Beta Regio are very similar as assumed earlier.

Nikishin, A. M.; Burba, G. A.



Geology and tectonics of Beta Regio, Guinevere Planitia, Sedna Planitia, and Western Eistla Regio, Venus - Results from Arecibo image data  

NASA Astrophysics Data System (ADS)

The geology of a portion of the equatorial region of Venus (1 deg S to 45 deg N and from 270 deg eastward to 30 deg) is assessed on the basis of new radar images obtained from the Arecibo Observatory. Nine geologic units are mapped on the basis of their radar characteristics, and their distribution and correspondences with topography are examined. Plains are the most abundant unit, comprising 80 percent of the area imaged, and are divided into bright, dark, and mottled. Mottled plains contain abundant lava flows and domes, suggesting that volcanism forming planes is a significant process in the equatorial region of Venus. Tesserae are found primarily on Beta Regio and its eastern flank and are interpreted to be locally stratigraphically older units, predating episodes of faulting and plains formation. On the basis of spatial and temporal relationships between geologic units, the highlands of Beta Regio and Western Eistla Regio are interpreted to have formed in association with areas of mantle upwelling which uplift plains, cause rifting, and, in the case of Beta Regio, disrupt a large region of tesserae.

Senske, D. A.; Fisher, P. C.; Head, J. W.; Aubele, J. C.; Campbell, D. B.; Stacy, N.; Stofan, E. R.; Hine, A. A.; Harmon, J. K.



Regio-and Enantioselective Alkane Hydroxylation with Engineered Cytochromes P450 BM-3  

E-print Network

Regio- and Enantioselective Alkane Hydroxylation with Engineered Cytochromes P450 BM-3 Matthew W alkanes regio- and enantioselectively using atmospheric dioxygen as an oxidant. BM-3 variant 9-10A-A328V alkanes larger than hexane primarily at the 2-position but forms R-2-alcohols (40-55% ee

Arnold, Frances H.


Rhynchodercetis regio, sp. nov., a dercetid fish (Teleostei: Aulopiformes) from Vallecillo, Nuevo León State, Northeastern Mexico  

Microsoft Academic Search

Description of Rhynchodercetis regio, sp. nov., from Upper Cretaceous (Turonian) sediments of Vallecillo, State of Nuevo León, northeastern Mexico is based on three specimens. Rhynchodercetis regio differs from the other species of Rhynchodercetis in the exclusive combination of characters that includes the proportions of the head with its standard length, the length of the preorbital area, and the presence of

Alberto Blanco; Jesús Alvarado-Ortega



Atla Regio, Venus: Geology and origin of a major equatorial volcanic rise  

NASA Technical Reports Server (NTRS)

Regional volcanic rises form a major part of the highlands in the equatorial region of Venus. These broad domical uplands, 1000 to 3000 km across, contain centers of volcanism forming large edifices and are associated with extension and rifting. Two classes of rises are observed: (1) those that are dominated by tectonism, acting as major centers for converging rifts such as Beta Regio and Alta Regio, and are termed tectonic junctions; and (2) those forming uplands characterized primarily by large-scale volcanism forming edifices. Western Eistla Regio and Bell Regio, where zones of extension and rifting are less developed. Within this second class of features the edifices are typically found at the end of a single rift, or are associated with a linear belt of deformation. We examine the geologic characteristics of the tectonic junction at Alta Regio, concentrating on documenting the styles of volcanism and assessing mechanisms for the formation of regional topography.

Senske, D. A.; Head, James W., III



Venus Ovda Regio Stratigraphy and Tectonics: Highlands-Plains Relationships  

NASA Astrophysics Data System (ADS)

The global plains materials of the Venusian lowlands, generally interpreted to be composed of flood basalts, lap onto the equatorial highlands of Western Aphrodite Regio. Systematic geologic mapping of the Ovda region using the Magellan global data (radar images, altimetry and gravity) has revealed that the contacts between highlands and plains have been tilted up toward the highlands after the plains emplacement. Analysis of the western part of Ovda Regio shows that the northern contact occurs at an average radius of 6053.8 km and the mean plains elevation 500 km to the north of the contact is at a radius of 6052.0 km, indicating that the boundary position has changed by nearly 2 km. Volcanic rilles are superposed on the tilted plains surfaces along both the northern and southern boundaries of the Ovda highlands. The local volcanicity that cut the rilles indicates that some local volcanic activity occurred subsequent to the marginal uplift. Models under study include post plains-emplacement uplift of the highlands or relative sinking of the plains. Isostatic mechanisms are likely in either case. Although complex structural models for the plains-highland margin are possible, simple structural models in which plains were emplaced as a nearly level geoidal surface and subsequently the highlands of Ovda were uplifted relative to the plains. Initial mapping is focused on 1:5,000,000 scale and is integrating observations of surface characteristics and geophysical inferences drawn from topography and gravity.

Saunders, R. S.



Geologic mapping of Northern Atla Regio on Venus: Preliminary data  

NASA Technical Reports Server (NTRS)

The Northern part of Atla Regio within the frame of C1-formate Magellan photo map 15N197 was mapped geologically at scale 1:8,000,000. This is a part of Russia's contribution into C1 geologic mapping efforts. The map is reproduced here being reduced about twice. The map shows that the Northern Atla area is predominantly a volcanic plain with numerous volcanic features: shield volcanoes, domes and hills with various morphology, corona-like constructions, radar bright and dark spots often with flow-like outlines. Relatively small areas of tessera occurred in the area are mainly semi-flooded with the plain material. Tesserae are considered to be the oldest terrains within the map sheet. There are many lineated terrains in the region. They are interpreted as the old, almost-buried tesserae (those with crossed lineaments) or partly buried ridge belts (those with parallel lineaments). These lineated terrains have an intermediate age between the young volcanic plains and the old tessera areas. Two prominent high volcanic shields are located within the region - Ozza Mons and Sapas Mona. The most prominent structure in Northern Atla is Ganis Chasma rift. The rift cuts volcanic plain and is considered to be under formation during approximately the same time with Ozza Mons shield. Ganis Chasma rift valley is highly fractured and bounded with fault scarps. Rift shoulder uplifts are typical for Ganis Chasma. There are few relatively young volcanic features inside the rift valley. The analysis of fracturing and rift valley geometry shows the rift originated due to 5-10 percent crustal extention followed by the crustal subsidence. The age sequence summary for the main terrain types in the region is (from older to younger ones): tesserae; lineated terrains with crossed lineaments; lineated terrains with parallel lineaments; volcanic plains; and prominent volcanic shields and Ganis Chasma rift valley. The geologic structure of Atla Regio as it appeared now with the Magellan high resolution images is very close to that of Beta Regio. Such conclusion coincide with the earlier ones based on the coarser data.

Nikishin, A. M.; Burba, G. A.



Untersuchungen an Regio olfactoria und Nervus olfactorius der Silbermöve ( Larus argentatus )  

Microsoft Academic Search

Summary After perfusion with glutaraldehyde and subsequent fixation with OsO4 the regio olfactoria of the gull (Larus argentatus) shows in alcohol with incident illumination a golden-brown interference colour. It is distinctly defined against the bluegreen regio respiratoria and covers in one side of the nasal cavity 71 mm2. The olfactory region demonstrates under a magnifier a “furlike” structure, produced by

Detlev Drenckhahn



RNA-Cleaving DNA Enzymes with Altered Regio- or Enantioselectivity  

NASA Technical Reports Server (NTRS)

In vitro evolution methods were used to obtain DNA enzymes that cleave either a 2',5' - phosphodiester following a wibonucleotide or a 3',5' -phosphodiester following an L-ribonucleotide. Both enzymes can operate in an intermolecular reaction format with multiple turnover. The DNA enzyme that cleaves a 2',5' -phosphodiester exhibits a k(sub cat) of approx. 0.01/ min and catalytic efficiency, k(sub cat)/k(sub m) of approx. 10(exp 5)/ M min. The enzyme that cleaves an L-ribonudeotide is about 10-fold slower and has a catalytic efficiency of approx. 4 x 10(exp 5)/ M min. Both enzymes require a divalent metal cation for their activity and have optimal catalytic rate at pH 7-8 and 35-50 C. In a comparison of each enzyme s activity with either its corresponding substrate that contains an unnatural ribonudeotide or a substrate that instead contains a standard ribonucleotide, the 2',5' -phosphodiester-deaving DNA enzyme exhibited a regioselectivity of 6000- fold, while the L-ribonucleotide-cleaving DNA enzyme exhibited an enantioselectivity of 50-fold. These molecules demonstrate how in vitro evolution can be used to obtain regio- and enantioselective catalysts that exhibit specificities for nonnatural analogues of biological compounds.

Ordoukhanian, Phillip; Joyce, Gerald F.



JOURNAL OF GEOPHYSICAL RESEARCH, VOL. 103,NO. E7, PAGES 16,841-16,853,JULY 25, 1998 Tectonic evolution of Bell Regio, Venus  

E-print Network

evolution of Bell Regio, Venus: lithospheric flexure, and edifice stresses PatriciaG. Rogersl RAND stressstateinthelithosphereofVenus(SAR)imagesandaltimetermeasurementsoftopography.ThemajorvolcanoesofBell Regio,TepevMonsandNyx Mons,exhibittectoniccharacteristicsthatareuniquerelativeto othervolcanicedificesonVenus

Zuber, Maria


J. Chem. Soc., Perkin Trans. 1, 1997 1779 Regio-and stereo-chemical outcomes in the nucleophilic ring cleavage  

E-print Network

the regio- and stereo-chemical outcomes of reactions involving nucleophilic ring-cleavage of the monoJ. Chem. Soc., Perkin Trans. 1, 1997 1779 Regio- and stereo-chemical outcomes in the nucleophilic ring cleavage reactions of mono-epoxides derived from cis-1,2-dihydrocatechols Martin G. Banwell,*, ,a

Hudlicky, Tomas


Venus - 3D Perspective View of Estla Regio  

NASA Technical Reports Server (NTRS)

A portion of western Eistla Regio is displayed in this three-dimensional perspective view of the surface of Venus. The viewpoint is located 1,100 kilometers (682 miles) northeast of Gula Mons at an elevation of 7.5 kilometers (4.6 miles). Lava flows extend for hundreds of kilometers across the fractured plains shown in the foreground to the base of Gula Mons. The viewpoint is to the southwest with Gula Mons appearing at the left just below the horizon. Gula Mons, a 3 kilometers (1.8 miles) high volcano, is located at approximately 22 degrees north latitude, 359 degrees east longitude. Sif Mons, a volcano with a diameter of 300 kilometers (180 miles) and a height of 2 kilometers (1.2 miles), appears to the right of Gula Mons. The distance between Sif Mons and Gula Mons is approximately 730 kilometers (453 miles). Magellan synthetic aperture radar data is combined with radar altimetry to develop a three-dimensional map of the surface. Ray tracing (rays as if from a light source are cast in a computer to intersect the surface) simulate a perspective view. Simulated color and a digital elevation map developed by Randy Kirk of the U.S. Geological Survey, are used to enhance small scale structure. The simulated hues are based on color images recorded by the Soviet Venera 13 and 14 spacecraft. The image was produced at the JPL Multimission Image Processing Laboratory by Eric De Jong, Jeff Hall and Myche McAuley, and is a single frame from a video released at a March 5, 1991, JPL news conference.



Iridium-catalyzed regio- and enantioselective allylic substitution of silyl dienolates derived from dioxinones.  


Reported herein is the iridium-catalyzed regio- and enantioselective allylic substitution reactions of unstabilized silyl dienolates derived from dioxinones. Asymmetric allylic substitution of a variety of allylic trichloroethyl carbonates with these silyl dienolates gave ?-allylated products selectively in 60-84?% yield and 90-98?%?ee. PMID:25223593

Chen, Ming; Hartwig, John F



The Use of pH to Influence Regio-and Chemoselectivity in the Asymmetric  

E-print Network

- S1 - The Use of pH to Influence Regio- and Chemoselectivity in the Asymmetric Aminohydroxylation-Hoover Capillary Melting Point Apparatus and are uncorrected. The pH of solutions was measured by AquemetTM Research AR15 pH meter equipped with Corning semimicrocombo electrode (#476156), which was standardized

Hergenrother, Paul J.


The Use of pH to Influence Regio-and Chemoselectivity in the Asymmetric  

E-print Network

The Use of pH to Influence Regio- and Chemoselectivity in the Asymmetric Aminohydroxylation, 2002 ABSTRACT The pH-controlled Sharpless asymmetric aminohydroxylation (AA) of styrenes provides 1 inversely correlated with enantiselectivity.3a We now report a method utilizing pH control to override other

Hergenrother, Paul J.


Een onderzoek naar de strategie van Nederlandse universiteiten voor maatschappelijke valorisatie in de regio  

E-print Network

in de regio Universiteit Leiden Masterscriptie Public Administration Msc track `Management van de van Amsterdam (UvA), de Universiteit Leiden (UL), Tilburg University (TiU) en de Universiteit Twente (UT). Ter verklaring van dit fenomeen is ook gekeken naar de positie van de gemeente als regionale

Twente, Universiteit


Regio- and stereoselective synthesis of 2-cyclopentenones via a hydrogenolysis-terminated Heck cyclization of ?-alkylthio dienones.  


Palladium-catalyzed cyclization of ?-alkylthio dienone derivatives affords 2-cyclopentenones in a regio- and stereoselective manner in the presence of silane. C-S activation, intramolecular carbopalladation and hydrogenolysis construct the cascade process. PMID:23396498

Liu, Bangyu; Zheng, Gang; Liu, Xiaocui; Xu, Cong; Liu, Jingxin; Wang, Mang



Regio- and stereocontrolled synthesis of oligostilbenoids: theoretical highlights at the supramolecular level.  


Oligostilbenoids (e.g., ampelopsin F, viniferin, pallidol) result from homogeneous or heterogeneous coupling of monomeric stilbenoid units, leading to various chemical structures. Oligostilbenoid synthesis is regio- and stereocontrolled. To tackle this regio- and stereocontrol, a supramolecular chemistry approach is required that can be achieved by quantum chemistry. The stability of noncovalent ?-stacks, formed between two stilbenoid units prior to oxidation, is accurately evaluated with density functional theory (DFT) including dispersive effects (within the DFT-D formalism). These noncovalent arrangements drive the regiocontrol. The rest of the chemical pathway is a succession of dearomatization and rearomatization stages. The thermodynamics and kinetics of the processes are calculated with classical hybrid functionals. This study allows discrimination between the two main possible chemical pathways, namely, radical-neutral and radical-radical reactions. The former appears more likely, thermodynamics and kinetics being in perfect agreement with the experimental 1:2 ratio obtained for ampelopsin F:pallidol analogues, respectively. PMID:23441649

Velu, Saraswati S; Di Meo, Florent; Trouillas, Patrick; Sancho-Garcia, Juan-Carlos; Weber, Jean-Frédéric F



Regio- and stereodivergent antibiotic oxidative carbocyclizations catalysed by Rieske oxygenase-like enzymes  

NASA Astrophysics Data System (ADS)

Oxidative cyclizations, exemplified by the biosynthetic assembly of the penicillin nucleus from a tripeptide precursor, are arguably the most synthetically powerful implementation of C-H activation reactions in nature. Here, we show that Rieske oxygenase-like enzymes mediate regio- and stereodivergent oxidative cyclizations to form 10- and 12-membered carbocyclic rings in the key steps of the biosynthesis of the antibiotics streptorubin B and metacycloprodigiosin, respectively. These reactions represent the first examples of oxidative carbocyclizations catalysed by non-haem iron-dependent oxidases and define a novel type of catalytic activity for Rieske enzymes. A better understanding of how these enzymes achieve such remarkable regio- and stereocontrol in the functionalization of unactivated hydrocarbon chains will greatly facilitate the development of selective man-made C-H activation catalysts.

Sydor, Paulina K.; Barry, Sarah M.; Odulate, Olanipekun M.; Barona-Gomez, Francisco; Haynes, Stuart W.; Corre, Christophe; Song, Lijiang; Challis, Gregory L.



Geology and structure of Beta Regio, Venus - Results from Arecibo radar imaging  

NASA Astrophysics Data System (ADS)

Arecibo radar images of a portion of the equatorial region of Venus provide the first high resolution (1.5- to 2.0-km) synoptic coverage of Beta Regio. Within this area, tessera, a complex deformed terrain, is identified as a major geologic unit with the largest region corresponding to a plateau on the east flank of the highland. Three models are proposed to explain the origin and evolution of Beta Regio and are identified as Mantle Plume/Passive Crust, Mantle Plume/Active Crust, and Mantle Plume/Crustal Spreading. The Mantle Plume/Passive Crust model appears to be the most consistent with the geology in this region and suggests that a plume disrupts a preexisting region of tessera.

Senske, D. A.; Head, J. W.; Stofan, E. R.; Campbell, D. B.



ZrCl4-mediated regio- and chemoselective Friedel-Crafts acylation of indole.  


An efficient method for regio- and chemoselective Friedel-Crafts acylation of indole using acyl chlorides in the presence of ZrCl(4) has been discovered. It minimizes/eliminates common competing reactions that occur due to high and multiatom-nucleophilic character of indole. In this method, a wide range of aroyl, heteroaroyl alkenoyl, and alkanoyl chlorides undergo smooth acylation with various indoles without NH protection and afford 3-acylindoles in good to high yields. PMID:21526849

Guchhait, Sankar K; Kashyap, Maneesh; Kamble, Harshad



Highly regio- and stereoselective nitro-oxoamination of mono-substituted allenes.  


A highly regio- and stereoselective (up to 99/1) nitro-oxoamination reaction of mono-substituted allene occurs under mild conditions with readily available AgNO2 and a free radical trap TEMPO to form one C-N bond and one C-O bond in one step. Various functional groups and heterocycles could be tolerated in this conversion. PMID:25347700

Xue, Can; Fu, Chunling; Ma, Shengming



Regio- and diastereo-selectivity of montmorillonite-catalyzed oligomerization of racemic adenosine 5'-phosphorimidazolide.  


Clay is a possible candidate for an effective catalyst in prebiotic chemical evolution of biomolecules. Montmorillonite was reported to effectively catalyze oligomerization of racemic adenosine 5'-phosphorimidazolide (DL-ImpA). In the oligomerization reaction, considerable amounts of cyclic dimers as well as linear dimers were produced in the oligomerization reactions. To assess the regio- and diastereo-selectivities of the oligomerization reaction, the dimer products including cyclic dimers were completely identified by means of enzymatic degradation reactions of the products. PMID:18404575

Urata, Hidehito; Fujimori, Mami; Aono, Chie; Yamakawa, Tomomi; Harada, Emi; Akagi, Masao



Biocatalyst mediated regio- and stereo-selective hydroxylation and epoxidation of (Z)-?-santalol.  


Biocatalyst mediated regio- and stereo-selective hydroxylation and epoxidation on (Z)-?-santalol were achieved for the first time, using a fungal strain Mucor piriformis. Four novel metabolites were characterized as 10,11-cis-?-epoxy-?-santalol, 5?-hydroxy-(Z)-?-santalol, 10,11-dihydroxy-?-santalol and 5?-hydroxy-10,11-cis-?-epoxy-?-santalol. Using Amano PS lipase from Burkholderia cepacia, ?- and ?-isomers of 10,11-cis-epoxy-?-santalol were resolved efficiently. PMID:24407157

Daramwar, Pankaj P; Srivastava, Prabhakar Lal; Kolet, Swati P; Thulasiram, Hirekodathakallu V



XVI Encontro de Economia da Regio Sul -ANPEC SUL 2013 XVI Encontro de Economia da Regio Sul  

E-print Network

XVI Encontro de Economia da Região Sul - ANPEC SUL 2013 1 XVI Encontro de Economia da Região Sul Programa de Pós Graduação em Desenvolvimento Econômico Curitiba - PR #12;XVI Encontro de Economia da Região/UFPR) Secretárias do PPGDE Aurea Koch Ivone Polo #12;XVI Encontro de Economia da Região Sul - ANPEC SUL 2013 3

Paraná, Universidade Federal do


Are the Basins of Tui Regio and Hotei Arcus Sites of Former Titanian Seas?  

NASA Technical Reports Server (NTRS)

Features observed in the basins of Tui Regio and Hotei Arcus on Titan have attracted the attention of the Cassini-era investigators. At both locations, VIMS observed discrete 5-micron bright approx.500-km wide features described as lobate in shape. Several studies have proposed that these materials are cryo-volcanic flows; in the case of the Hotei Arcus feature this inference was buttressed with SAR RADAR images showing bright and dark patches with lobate margins. We propose an alternative explanation. First we note that all landforms on Titan that are unambiguously identifiable can be explained by exogenic processes (aeolian, fluvial, impact cratering, and mass wasting). Suggestions of endogenically produced cryovolcanic constructs and flows have, without exception, lacked conclusive diagnostic evidence. Recently published topographic profiles across Tui Regio and the lobate feature region north of Hotei Arcus indicate these features appear to occur in large regional basins, at least along the direction of the profiles. SAR images show that the terrains surrounding both 5-micron bright features exhibit fluvial networks that appear to converge and debauch into the probable basins. The 5-micron bright features themselves correspond to fields of discrete radar-bright depressions whose bounding edges are commonly rounded and cumulate in planform in SAR images. These fields of discrete radar-bright depressions strongly resemble fields of features seen at Titan s high latitudes usually attributed to be dry lakes. Thus the combination of (1) the resemblance to high-latitude dry lakes, (2) location in the centers of probable regional depressions, and (3) convergence of fluvial networks are inferred by us to best explain the 5-micron bright regions at Tui Regio and Hotei Arcus as sites of dry seas or at least paleolake clusters. Such equatorial seas, if real, may be evidence of substantially larger inventories of liquid alkanes in Titan s past.

Moore, Jeffrey Morgan; Howard, Alan



Are the Basins of Tui Regio and Hotei Arcus Sites of Former Titanian Seas?  

NASA Astrophysics Data System (ADS)

Features observed in the basins of Tui Regio and Hotei Arcus on Titan have attracted the attention of the Cassini-era investigators. At both locations, VIMS observed discrete 5-micron bright 500-km wide features described as lobate in shape. Several studies have proposed that these materials are cryo-volcanic flows; in the case of the Hotei Arcus feature this inference was buttressed with SAR RADAR images showing bright and dark patches with "lobate” margins. We propose an alternative explanation. First we note that all landforms on Titan that are unambiguously identifiable can be explained by exogenic processes (aeolian, fluvial, impact cratering, and mass wasting). Suggestions of endogenically produced cryovolcanic constructs and flows have, without exception, lacked conclusive diagnostic evidence. Recently published topographic profiles across Tui Regio and the "lobate” feature region north of Hotei Arcus indicate these features appear to occur in large regional basins, at least along the direction of the profiles. SAR images show that the terrains surrounding both 5-micron bright features exhibit fluvial networks that appear to converge and debauch into the probable basins. The 5-micron bright features themselves correspond to fields of discrete radar-bright depressions whose bounding edges are commonly rounded and cumulate in planform in SAR images. These fields of discrete radar-bright depressions strongly resemble fields of features seen at Titan's high latitudes usually attributed to be dry lakes. Thus the combination of (1) the resemblance to high-latitude dry lakes, (2) location in the centers of probable regional depressions, and (3) convergence of fluvial networks are inferred by us to best explain the 5-micron bright regions at Tui Regio and Hotei Arcus as sites of dry seas or at least paleolake clusters. Such equatorial seas, if real, may be evidence of substantially larger inventories of liquid alkanes in Titan's past.

Moore, Jeffrey M.; Howard, A. D.



Regio- and stereoselective oxidation of unactivated C-H bonds with Rhodococcus rhodochrous  

PubMed Central

Summary The ability of Rhodococcus rhodochrous (NCIMB 9703) to catalyse the regio- and stereoselective hydroxylation of a range of benzyloxy-substituted heterocycles has been investigated. Incubation of 2-benzyloxytetrahydropyrans with resting cell suspensions of the organism yielded predominantly a mixture of 5-hydroxylated isomers in combined yields of up to 40%. Exposure of the corresponding 2-benzyloxytetrahydrofuran derivatives to the cell suspensions gave predominantly the 4-hydroxylated isomers in yields of up to 26%. Most interestingly, 2-(4-nitrobenzyloxy)tetrahydrofuran and 2-(4-nitrobenzyloxy)tetrahydropyran were transformed in high yields to the 4-hydroxylated and 5-hydroxylated products, respectively. PMID:22509221

O'Reilly, Elaine; Aitken, Suzanne J; Grogan, Gideon; Kelly, Paul P; Turner, Nicholas J



Structural architecture and a new tectonic perspective of Ovda Regio, Venus  

NASA Astrophysics Data System (ADS)

The structural architecture of the Ovda Regio, Venus, derived from regional and detailed structural mapping of several key segments, reveals a new tectonic perspective, for the first time that varies from most of the existing tectonic models. The interpreted structural features include folds of different styles and scales, mega shear zones, ribbon structures, and other kinematic indicators. While concentric folding is predominant in the western Ovda, the eastern Ovda is characterized by shear folding. Two mega shear zones are recognised: dextral NW-SE trending GMSZ and a complimentary sinistral NE-SW trending KKSZ. Two tectonic stages are identified in a coherent and continuous strain history involving initial N-S compression that gave rise to regional east-west folding providing the fundamental tectonic architecture of a mountain fold-thrust belt. Ribbon structures in a broad radial pattern were developed contemporaneously with this folding. The second tectonic stage saw the development of a conjugate pair of mega shear zones and a range of kinematic indicators, consistent with continued N-S compression and the pre-existing fold pattern was modified resulting in the development of new fold structures, particularly in the eastern Ovda. The structural characteristics of Ovda Regio are analogous to those of Himalaya-Tibet collision front and also the Precambrian mobile belts of southern India.

Chetty, T. R. K.; Venkatrayudu, M.; Venkatasivappa, V.



Regio- and chemoselective magnesiation of protected uracils and thiouracils using TMPMgCl x LiCl and TMP(2)Mg x 2 LiCl.  


Two successive regio- and chemoselective magnesiations using TMPMgCl x LiCl and TMP(2)Mg x 2 LiCl enable the full functionalization of protected uracils and thiouracils in good to excellent yields. PMID:18802627

Mosrin, Marc; Boudet, Nadège; Knochel, Paul



A mild, efficient and environmentally friendly method for the regio- and chemoselective synthesis of enaminones using Bi(TFA) 3 as a reusable catalyst in aqueous media  

Microsoft Academic Search

Bismuth(III) trifluoroacetate has been found to be an extremely efficient catalyst for the preparation of ?-enaminones in water. In addition, by employing this catalyst, high regio- and chemoselective enamination of carbonyl compounds was achieved.

Ahmad R. Khosropour; Mohammad M. Khodaei; Mehdi Kookhazadeh



Regio- and stereochemical studies on the alpha-carbon oxidation of (S)-nicotine by cytochrome P-450 model systems.  


Results from previous studies indicate that rabbit liver microsomal cytochrome P-450 catalyzes the C-5' two-electron oxidation of (S)-nicotine stereoselectivity with preferential loss of the pro-(E)-hydrogen atom trans to the pyridine ring. We now have examined the regio- and stereochemical features of the oxidation of (S)-nicotine by peroxides in the presence of various hemoproteins and by electrochemical and photochemical methods. None of these systems gave rise to the stereochemical outcomes observed with the cytochrome P-450 mediated reaction. The results of these studies are interpreted as additional evidence for the formation of a highly ordered complex between (S)-nicotine and cytochrome P-450 that directs the regio- and diasterioselective alpha-carbon oxidation of this substrate. PMID:3346880

Peterson, L A; Castagnoli, N



Cobalt- and nickel-catalyzed regio- and stereoselective reductive coupling of alkynes, allenes, and alkenes with alkenes.  


Transition-metal-catalyzed coupling of two different C-C pi components through a metallacycle intermediate is a highly atom economical method to construct C-C bonds in organic synthesis. The metal-catalyzed coupling of an alkene and alkyne generally gives an Alder-ene or reductive coupling product. In this article, we focus on the cobalt- and nickel-catalyzed reductive coupling of alkynes, allenes, and alkenes with alkenes. These reductive coupling reactions provide convenient methods for the synthesis of various alkenes, dienes, functionalized alkanes, lactones, lactams, and cyclic alcohols in a highly regio- and stereoselective manner. A chemselective formation of metallacyclopentene intermediate from the two different C-C pi components and a low-valence metal species plays a key role for the high regio- and stereoselectivity of the catalytic reaction. PMID:18850608

Jeganmohan, Masilamani; Cheng, Chien-Hong



Ruthenium-catalyzed highly regio- and stereoselective hydroarylation of aromatic sulfoxides with alkynes via C-H bond activation.  


Chelation-assisted alkenylation at the ortho C-H bond of aromatic sulfoxides with alkynes in the presence of a ruthenium catalyst, AgSbF6 and pivalic acid yielding trisubstituted alkenes in good to excellent yields in a highly regio- and stereoselective manner via a deprotonation metalation pathway is described. Later, ortho-alkenylated aromatic sulfoxides were converted into ?-acyloxy-thioether and a 2,3-disubstituted benzothiophene derivative. PMID:25307797

Padala, Kishor; Jeganmohan, Masilamani



Bell Regio, Venus: Integration of remote sensing data and terrestrial analogs for geologic analysis  

NASA Technical Reports Server (NTRS)

The geology and surface morphology of Bell Regio (18-42 deg N, 32-58 deg E) are investigated using a combination of Magellan, Venera, and analogous terrestrial data. The properties of surface units are compared to either direct terrestrial analog measurements or to the behaviors predicted by theoretical models. Five major volcanic sources are identified from geologic mapping (Tepev Mons, Nefertiti corona, a large shield volcano east of Tepev, and two small edifices southeast of Tepev). The volcano Api Mons lies northeast of the main Bell uplift. The oldest volcanic units are associated with an extensive low shield volcano east of Tepev Mons and a small edifice southeast of Tepev. The annular flow apron of Tepev Mons formed next, with volcanism at a second small edifice on the southeast flank of Tepev Mons producing the youngest flow units. Comparisons between Magellan data, terrestrial radar images, and field topography profiles suggest that only three units resemble terrestrial a'a flows; the remainder are consistent with smoother pahoehoe-type surfaces. This suggests that most of the flow units were erupted at relatively low volume effusion rates (less than 100 cu m/sec) over long periods of time or had very low viscosities

Campbell, Bruce A.; Rogers, Patricia G.



Magellan 3D perspective of Venus surface in western Eistla Regio  

NASA Technical Reports Server (NTRS)

Magellan synthetic aperture radar data was used to create this three- dimensional (3D) perspective view of Venus' western Eistla Regio. This viewpoint is located at 1,310 kilometers (812 miles) southwest of Gula Mons at an elevation of 0.178 kilometers (0.48 miles). The view is of the northeast with Gula Mons appearing on the horizon. Gula Mons, a 3 kilometer (1.86 mile) high volcano, is located at approximately 22 degrees north latitude, 359 degrees east longitude. The impact crater Cunitz, named for the astronomer and mathematician Maria Cunitz, is visible in the center of the image. The crater is 48.5 kilometers (30 miles) in diameter and is 215 kilometers (133 miles) from the viewer's position. Magellan synthetic aperture radar data is combined with radar altimetry to develop a 3D map of the surface. Rays cast in a computer intersect the surface to create a 3D view. Simulated color and a digital elevation map developed by the United States (U.S.) Geological Survey is used to enhanc



Regio- and Stereospecific Conversion of 4-Alkylphenols by the Covalent Flavoprotein Vanillyl-Alcohol Oxidase  

PubMed Central

The regio- and stereospecific conversion of prochiral 4-alkylphenols by the covalent flavoprotein vanillyl-alcohol oxidase was investigated. The enzyme was active, with 4-alkylphenols bearing aliphatic side chains of up to seven carbon atoms. Optimal catalytic efficiency occurred with 4-ethylphenol and 4-n-propylphenols. These short-chain 4-alkylphenols are stereoselectively hydroxylated to the corresponding (R)-1-(4?-hydroxyphenyl)alcohols (F. P. Drijfhout, M. W. Fraaije, H. Jongejan, W. J. H. van Berkel, and M. C. R. Franssen, Biotechnol. Bioeng. 59:171–177, 1998). (S)-1-(4?-Hydroxyphenyl)ethanol was found to be a far better substrate than (R)-1-(4?-hydroxyphenyl)ethanol, explaining why during the enzymatic conversion of 4-ethylphenol nearly no 4-hydroxyacetophenone is formed. Medium-chain 4-alkylphenols were exclusively converted by vanillyl-alcohol oxidase to the corresponding 1-(4?-hydroxyphenyl)alkenes. The relative cis-trans stereochemistry of these reactions was strongly dependent on the nature of the alkyl side chain. The enzymatic conversion of 4-sec-butylphenol resulted in two (4?-hydroxyphenyl)-sec-butene isomers with identical masses but different fragmentation patterns. We conclude that the water accessibility of the enzyme active site and the orientation of the hydrophobic alkyl side chain of the substrate are of major importance in determining the regiospecific and stereochemical outcome of vanillyl-alcohol oxidase-mediated conversions of 4-alkylphenols. PMID:9791114

van den Heuvel, Robert H. H.; Fraaije, Marco W.; Laane, Colja; van Berkel, Willem J. H.



Fractal analysis of Venus topography in Tinatin Planitia and Ovda Regio  

NASA Technical Reports Server (NTRS)

A one-dimensional fractal analysis is applied to Magellan altimetry data for two 20 x 20 deg equatorial regions on Venus. For the Ovda Regio, highlands the power spectra of the altimetry data correlate well with power law (fractal) statistics over the full range of wavelengths considered 36-703 km; the mean fractal dimension is D(Ovda) = 1.64. For the Tinatin Planitia lowlands, the power spectra consistently show a rollover at long wavelengths, (greater than 200 km), the long-wavelength topography in this region either never developed or has subsequently relaxed. The mean of the best fit fractal dimension for Tinatin is D(Tinatin) = 1.41. The measure of roughness (RA) correlates well with variations in relief, especially at short wavelengths (about 50 km). The quantitative analysis of Venus topography can be applied on a global scale. The one-dimensional method can be extended to two-dimensional space, yielding two-dimensional maps of regional D and RA, allowing a more complete use of regional two-dimensional altimetry data.

Kucinskas, Algis B.; Turcotte, Donald L.; Huang, Jie; Ford, Peter G.



Estimating Regio and Stereoselectivity in [4+2] Cycloadditions of Vinyl-Substituted Cyclic Dienes with Maleic Anhydride  

NASA Astrophysics Data System (ADS)

Density functional theory calculations are performed to examine the regio and stereoselective preferences in [4+2] cycloaddition reactions of vinyl cyclopentadiene (1 and 2) and vinyl heterocyclic (1-N, 1-O, 1-S, 2-N, 2-O and 2-S) systems with maleic anhydride. Stepwise and concerted pathways of model systems 1 and 2 as dienes with ethylene as dienophile reveal that the reactions proceed through asynchronous and concerted pathway. 3-Vinyl systems (2) are predicted to be more reactive compared to 2-vinyl systems (1). The regio and stereoselective preferences are evaluated based on activation energies, reaction energies, density functional based descriptors and atoms in molecules analysis. In all cases, extra-annular cycloadducts are more feasible compared to intra-annular cycloadducts. Stereoselectivity depends on the favorable secondary orbital interactions. Solvents such as water, tetrahydrofuran, acetone, and dimethyl sulphoxide are employed to understand the effects of solvents on the cycloadduct formation. The computational results thus obtained are compared with the earlier experimental observations that are available.

Gayatri, Gaddamanugu; Sastry, G. Narahari



Photocycloadditions of substituted oxazoles with isoquinoline-1,3,4-trione--chemo-, regio-, diastereoselectivities and transformation of the photocycloadducts.  


Photoreactions of isoquinoline-1,3,4-triones and oxazoles with different substituents were found to give different chemo-, regio- and diastereoselectivities. The substituent at the C5 on the oxazole ring showed great influence on the chemoselectivity of the photoreaction as well as on the transformation of the photocycloadducts. The 2-methyl-5-methoxyoxazoles reacted with isoquinoline-1,3,4-triones rapidly and gave spirooxetanes with high regio- and diastereo-selectivity. Diastereoselectivity in the reaction of 2-phenyl-5-methoxyoxazoles with isoquinoline-1,3,4-triones was relevant to the substituent on the 4-position on the oxazole ring. Replacement of the 5-methoxy group with 5-methyl or 5-phenyl resulted in significant decrease on the reactivity of the oxazole as well as change on the diastereoselectivity in photocycloaddition with isoquinoline-1,3,4-triones. Acid-mediated transformations of the photocycloadduct spirooxetanes was found to give different type of products including ?-hydroxy-?-aminocarbonyl compounds and spiroisoquinolineoxazolines under different reaction conditions. Substituents on the spirooxetanes as well as the type and amount of acid used in the reaction played important roles in determining the type and diastereoselectivity of the products in the transformations. PMID:23801247

Huang, Cheng-mei; Jiang, Heng; Wang, Ru-zhi; Quah, Ching Kheng; Fun, Hoong-Kun; Zhang, Yan



Venus - 3D Perspective View of Eastern Edge of Alpha Regio  

NASA Technical Reports Server (NTRS)

A portion of the eastern edge of Alpha Regio is displayed in this three-dimensional perspective view of the surface of Venus. The viewpoint is located at approximately 30 degrees south latitude, 11.8 degrees east longitude at an elevation of 2.4 kilometers (3.8 miles). The view is to the northeast at the center of an area containing seven circular dome-like hills. The average diameter of the hills is 25 kilometers (15 miles) with maximum heights of 750 meters (2,475 feet). Three of the hills are visible in the center of the image. Fractures on the surrounding plains are both older and younger than the domes. The hills may be the result of viscous or thick eruptions of lava coming from a vent on the relatively level ground, allowing the lava to flow in an even lateral pattern. The concentric and radial fracture patterns on their surfaces suggests that a chilled outer layer formed, then further intrusion in the interior stretched the surface. An alternative interpretation is that domes are the result of shallow intrusions of molten lava, causing the surface to rise. If they are intrusive, then magma withdrawal near the end of the eruptions produced the fractures. The bright margins possibly indicate the presence of rock debris or talus at the slopes of the domes. Resolution of the Magellan data is about 120 meters (400 feet). Magellan's synthetic aperture radar is combined with radar altimetry to develop a three-dimensional map of the surface. A perspective view is then generated from the map. Simulated color and a process called radar-clinometry are used to enhance small-scale structures. The simulated hues are based on color images recorded by the Soviet Venera 13 and 14 spacecraft. The image was produced by the JPL Multimission Image Processing Laboratory by Eric De Jong, Jeff Hall, Myche McAuley, and Randy Kirk of the United States Geological Survey, and is a single frame from the movie released at the May 29, 1991 Magellan news conference.



Structural determination by NMR spectroscopy and molecular mechanics of the regio and diastereoisomers obtained in the addition of 2-phenylcyclohexanone to chalcone  

Microsoft Academic Search

The structure and stereochemistry of the six regio and stereoisomers obtained in the reaction of 2-Phenylcyclohexanone 1 with chalcone 2 by solvent-free phase transfer catalysis has been determined by a combination of NMR techniques and molecular mechanics calculations. The validity of the method has been confirmed by the X-ray structure determination of isomer 7.

A. de la Hoz; E. Díez-Barra; F. Langa; S. Merino; A. Rodríguez; P. Sánchez-Verdú



Palladium-catalyzed highly regio- and stereoselective synthesis of 4-alkylidene-4H-3,1-benzoxazines from N-acyl-o-alkynylanilines.  


The highly regio- and stereoselective 6-exo-dig mode cyclization of N-acyl-o-alkynylanilines producing 4-alkylidene-3,1-benzoxazines occurred unpredictably by use of a proper catalyst [Pd(OAc)(2)] and an effective additive (acetic acid) under suitable reaction conditions. PMID:21291205

Saito, Takao; Ogawa, Shohei; Takei, Naoya; Kutsumura, Noriki; Otani, Takashi




E-print Network

A GEST�O DAS ÁGUAS SUBTERR�NEAS NA REGI�O SUDESTE DO ESTADO DE TOCANTINS Waldir Duarte Costa1 hidrogeológico da Região Sudeste do Estado do Tocantins foram cadastrados 1.080 em toda a área, distribuídos em três distintas províncias geológicas a saber: Província de Tocantins representada por metamorfitos e

Paris-Sud XI, Université de


Regio- and stereoselective synthesis of ferrocene-containing ?-iodoallylic esters and ethers from the iodofunctionalization of ferrocenylallene with carboxylic acids, phenols, and alcohols.  


The iodofunctionalization of ferrocenylallene with carboxylic acids, phenols, and alcohols is described. The reaction proceeds smoothly in the presence of molecule iodine as a halonium promoter and using various carboxylic acids, phenols, and alcohols as nucleophiles to give the corresponding ferrocene-containing ?-iodoallylic ester and ether products in moderate to high yields and with high regio- and stereoselectivities. It can be envisaged that the regio- and stereoselectivity of this reaction may be controlled by the steric effect of the bulky ferrocene group. The presence of the C-I bond in the corresponding products makes these molecules highly attractive from a synthetic point of view, as it provides an opportunity for further transformations. Thus, palladium-catalyzed Heck coupling, Suzuki coupling, Sonogashira coupling, and copper-catalyzed click reactions were carried out successfully. PMID:24855998

Chen, Shufeng; Zhang, Hongli; Yan, Qing; Wang, Chenjun; Han, Fei; Zhang, Kaixin; Zhao, Haiying; Li, Baoguo



Relatrio da expedio realizada na regio do rio Pirawiri / Parque Nacional Montanhas de Tumucumaque  

E-print Network

exploração da bacia do rio Cuc, antiga área de moradia de grupos Wajãpi hoje localizados em grande parte na serão visitados. Com o mapeamento das localizações antigas, esperava-se entender melhor uma fase recente si era uma antiga idéia do cacique Waiwai, que expressou vá

Paris-Sud XI, Université de


Regio- and enantio-selective glycosylation of tetrahydroprotoberberines by Gliocladium deliquescens NRRL1086 resulting in unique alkaloidal glycosides.  


The microbial transformation of a series of tetrahydroprotoberberines (THPBs, 1-5) by Gliocladium deliquescens NRRL1086 was investigated. In this research, the novel glycosylation of tetrahydroberberrubine (1) was observed with fast rate and high regio- and enantio-selectivity. One pair of unique enantiomorphic alkaloidal glycosides T-1 and T-2 was isolated and their structures were elucidated unambiguously by HR-MS, CD, 1D and 2D NMR spectrum. It is interesting that different amounts of glucose in the potato broth medium could influence the ratio of T-1 and T-2; in the 1.5% glucose medium, the ratio was about 15:1 and the yield of the S-form product T-1 may reach the theoretical maximum yield of about 50% which could provide one practical method to prepare the enantiomerically pure product and one alternative resolution method of tetrahydroberberrubine. The preliminary enzymatic research by using sodium dodecyl sulfate (SDS) and imidazole as glycosyltransferase and glycosidase inhibitors revealed that glycosyltransferase may contribute to glycosylation process. This is the first successful approach to glycosylation of tetrahydroprotoberberines. PMID:22189862

Ge, Hai-Xia; Zhang, Jian; Kai, Cui; Liu, Ji-Hua; Yu, Bo-Yang



Regio- and Enantioselective N-Allylations of Imidazole, Benzimidazole, and Purine Heterocycles Catalyzed by Single-Component Metallacyclic Iridium Complexes  

PubMed Central

Highly regio- and enantioselective iridium-catalyzed N-allylations of benzimidazoles, imidazoles, and purines have been developed. N-Allylated benzimidazoles and imidazoles were isolated in high yields (up to 97%) with high branched-to-linear selectivity (up to 99:1) and enantioselectivity (up to 98% ee) from the reactions of benzimidazole and imidazole nucleophiles with unsymmetrical allylic carbonates in the presence of single component, ethylene-bound, metallacyclic iridium catalysts. N-Allylated purines were also obtained in high yields (up to 91%) with high N9:N7 selectivity (up to 96:4), high branched-to-linear selectivity (98:2), and high enantioselectivity (up to 98% ee) under similar conditions. The reactions encompass a range of benzimidazole, imidazole, and purine nucleophiles, as well as a variety of unsymmetrical aryl, heteroaryl, and aliphatic allylic carbonates. Competition experiments between common amine nucleophiles and the heterocyclic nitrogen nucleophiles studied in this work illustrate the effect of nucleophile pKa on the rate of iridium-catalyzed N-allylation reactions. Kinetic studies on the allylation of benzimidazole catalyzed by metallacyclic iridium-phosphoramidite complexes, in combination with studies on the deactivation of these catalysts in the presence of heterocyclic nucleophiles, provide insight into the effects of the structure of the phosphoramidite ligands on the stability of the metallacyclic catalysts. The data obtained from these studies has led to the development of N-allylations of benzimidazoles and imidazoles in the absence of an exogenous base. PMID:19480431

Stanley, Levi M.



Photoinduced [4 + 4], [4 + 2], and [2 + 2] cycloadditions of o-quinones with oxazoles: chemo-, regio-, and diastereoselectivity.  


Photoinduced reactions of the 1,2-dicarbonyl compounds phenanthrenequinone (PQ), 1-acetylisatin (IS), and benzil (BZ) with the oxazoles 1a-j have been investigated. In photoreactions of PQ with the oxazoles, in addition to the 1,4-dioxins derived from [4 + 2] cycloaddition and the oxetanes from the Paternó-Büchi [2 + 2] reactions, [4 + 4] cycloaddition products are formed in the reactions with 1a, 1c, 1g, 1i, and 1j, with the quinone's dicarbonyl unit (O?C-C?O) and the oxazole's C?N-C?C moiety as two 4? addends. Photoreactions of IS with the oxazoles 1f and 1g give the [4 + 4] cycloaddition products exclusively, while in photoreactions of IS with 1a, 1c, 1e, 1h, and 1i, [4 + 4] products are formed together with the [2 + 2] products. Reaction pathway partitioning in these photocycloaddtions strongly depends on the substitution pattern on the oxazole ring. The presence of a substituent at the oxazole's C2 atom hampers the [4 + 4] pathway by causing steric hindrance to radical pair recombination in the corresponding 1,7-diradical intermediate to form the [4 + 4] cycloaddition products. A substituent at the C4 atom results in steric hindrance for ring closure of the 1,4-diradicals in the [2 + 2] cycloaddition pathway, therefore favoring the [4 + 4] and [4 + 2] cycloaddition pathways. Regio- and diastereoselectivity in the [2 + 2] and [4 + 4] cycloadditions have been discussed based on the thermodynamic stability of the relevant triplet diradical intermediates and the conformations of these diradicals suitable for the intersystem crossing process. Photoreactions of BZ with the oxazoles afford only [2 + 2] cycloaddition products. PMID:21028907

Wang, Lei; Huang, Yu-Cheng; Liu, Yang; Fun, Hoong-Kun; Zhang, Yan; Xu, Jian-Hua



Regio- and stereo-selective metabolism of 4-methylbenz[a]anthracene by the fungus Cunninghamella elegans.  

PubMed Central

Metabolism of 4-methylbenz[a]anthracene by the fungus Cunninghamella elegans was studied. C. elegans metabolized 4-methylbenz[a]anthracene primarily at the methyl group, this being followed by further metabolism at the 8,9- and 10,11-positions to form trans-8,9-dihydro-8,9-dihydroxy-4-hydroxymethylbenz[a]anthracene and trans-10,11-dihydro-10,11-dihydroxy-4-hydroxymethylbenz[a]anthracene. There was no detectable trans-dihydrodiol formed at the methyl-substituted double bond (3,4-positions) or at the 'K' region (5,6-positions). The metabolites were isolated by reversed-phase high-pressure liquid chromatography and characterized by the application of u.v.-visible-absorption-, 1H-n.m.r.- and mass-spectral techniques. The 4-hydroxymethylbenz[a]anthracene trans-8,9- and -10,11-dihydrodiols were optically active. Comparison of the c.d. spectra of the trans-dihydrodiols formed from 4-methylbenz[a]anthracene by C. elegans with those of the corresponding benz[a]anthracene trans-dihydrodiols formed by rat liver microsomal fraction indicated that the major enantiomers of the 4-hydroxymethylbenz[a]anthracene trans-8,9-dihydrodiol and trans- 10,11-dihydrodiol formed by C. elegans have S,S absolute stereochemistries, which are opposite to those of the predominantly 8R,9R- and 10R,11R-dihydrodiols formed by the microsomal fraction. Incubation of C. elegans with 4-methylbenz[a]anthracene under 18O2 and subsequent mass-spectral analysis of the metabolites indicated that hydroxylation of the methyl group and the formation of trans-dihydrodiols are catalysed by cytochrome P-450 mono-oxygenase and epoxide hydrolase enzyme systems. The results indicate that the fungal mono-oxygenase-epoxide hydrolase enzyme systems are highly stereo- and regio-selective in the metabolism of 4-methylbenz[a]anthracene. PMID:6661203

Cerniglia, C E; Fu, P P; Yang, S K



Functional Characterization of Premnaspirodiene Oxygenase, a Cytochrome P450 Catalyzing Regio- and Stereo-specific Hydroxylations of Diverse Sesquiterpene Substrates*s  

PubMed Central

Solavetivone, a potent antifungal phytoalexin, is derived from a vetispirane-type sesquiterpene, premnaspirodiene, by a putative regio- and stereo-specific hydroxylation, followed by a second oxidation to yield the ?,?-unsaturated ketone. Mechanistically, these reactions could occur via a single, multifunctional cytochrome P450 or some combination of cytochrome P450s and a dehydrogenase. We report here the characterization of a single cytochrome P450 enzyme, Hyoscyamus muticus premna-spirodiene oxygenase (HPO), that catalyzes these successive reactions at carbon 2 (C-2) of the spirane substrate. HPO also catalyzes the equivalent regio-specific (C-2) hydroxylation of several eremophilane-type (decalin ring system) sesquiterpenes, such as with 5-epi-aristolochene. Moreover, HPO displays interesting comparisons to other sesquiterpene hydroxylases. 5-Epi-aristolochene di-hydroxylase (EAH) differs catalytically from HPO by introducing hydroxyl groups first at C-1, then C-3 of 5-epi-aristolochene. HPO and EAH also differ from one another by 91-amino acid differences, with four of these differences mapping to putative substrate recognition regions 5 and 6. These four positions were mutagenized alone and in various combinations in both HPO and EAH and the mutant enzymes were characterized for changes in substrate selectivity, reaction product specificity, and kinetic properties. These mutations did not alter the regio- or stereo-specificity of either HPO or EAH, but specific combinations of the mutations did improve the catalytic efficiencies 10–15-fold. Molecular models and comparisons between HPO and EAH provide insights into the catalytic properties of these enzymes of specialized metabolism in plants. PMID:17715131

Takahashi, Shunji; Yeo, Yun-Soo; Zhao, Yuxin; O'Maille, Paul E.; Greenhagen, Bryan T.; Noel, Joseph P.; Coates, Robert M.; Chappell, Joe



Mineral chemistry of MUSES-C Regio inferred from analysis of dust particles collected from the first- and second-touchdown sites on asteroid Itokawa  

NASA Astrophysics Data System (ADS)

The mineralogy and mineral chemistry of Itokawa dust particles captured during the first and second touchdowns on the MUSES-C Regio were characterized by synchrotron-radiation X-ray diffraction and field-emission electron microprobe analysis. Olivine and low- and high-Ca pyroxene, plagioclase, and merrillite compositions of the first-touchdown particles are similar to those of the second-touchdown particles. The two touchdown sites are separated by approximately 100 meters and therefore the similarity suggests that MUSES-C Regio is covered with dust particles of uniform mineral chemistry of LL chondrites. Quantitative compositional properties of 48 dust particles, including both first- and second-touchdown samples, indicate that dust particles of MUSES-C Regio have experienced prolonged thermal metamorphism, but they are not fully equilibrated in terms of chemical composition. This suggests that MUSES-C particles were heated in a single asteroid at different temperatures. During slow cooling from a peak temperature of approximately 800 °C, chemical compositions of plagioclase and K-feldspar seem to have been modified: Ab and Or contents changed during cooling, but An did not. This compositional modification is reproduced by a numerical simulation that modeled the cooling process of a 50 km sized Itokawa parent asteroid. After cooling, some particles have been heavily impacted and heated, which resulted in heterogeneous distributions of Na and K within plagioclase crystals. Impact-induced chemical modification of plagioclase was verified by a comparison to a shock vein in the Kilabo LL6 ordinary chondrite where Na-K distributions of plagioclase have been disturbed.

Nakamura, Tomoki; Nakato, Aiko; Ishida, Hatsumi; Wakita, Shigeru; Noguchi, Takaaki; Zolensky, Michael E.; Tanaka, Masahiko; Kimura, Makoto; Tshuchiyama, Akira; Ogami, Toshihiro; Hashimoto, Takahito; Konno, Mitsuru; Uesugi, Masayuki; Yada, Toru; Shirai, Kei; Fujimura, Akio; Okazaki, Ryuji; Sandford, Scott. A.; Ishibashi, Yukihiro; Abe, Masanao; Okada, Tatsuaki; Ueno, Munetaka; Kawaguchi, Junichiro



Regio- and stereoselective synthesis of spirooxindole 1'-nitro pyrrolizidines with five concurrent stereocenters under aqueous medium and their bioprospection using the zebrafish (Danio rerio) embryo model.  


A highly regio- and stereoselective method has been developed and expanded for the synthesis of a 20-membered library of spirooxindole 1'-nitro pyrrolizidines via 1,3-dipolar cycloaddition of azomethine ylides, generated in situ by a decarboxylative route from a common set of diverse isatins and L-proline derivatives, with substituted ?-nitrostyrenes under aqueous medium. Among various reaction conditions, water proved to be necessary for the interaction of the reagents as well as heating the reaction at 90 °C for one hour, during which time the desired products were obtained in good yields and with excellent regio- and stereoselectivities. We subsequently applied in silico drug discovery computational methods to (i) identify the ADME properties, based on Lipinski's rule, (ii) screen the toxicological profile, and (iii) predict the penetration through the blood brain barrier (BBB) of the synthesized compounds. Next, the LC50 values of all these spirocyclic oxindoles were determined in zebrafish embryos cultured individually in buffer solutions of each compound and, finally, the phenotypes induced by these molecules in the zebrafish embryos at concentrations below their LC50 were analyzed at 48, 72 and 96 hours post fertilization. PMID:24065047

Puerto Galvis, Carlos E; Kouznetsov, Vladimir V



ent-Kaurane-based regio- and stereoselective inverse electron demand hetero-Diels-Alder reactions: synthesis of dihydropyran-fused diterpenoids.  


A mild and concise approach for the construction of a 3,4-dihydro-2H-pyran ring integrated into the A-ring of the natural product oridonin using an optimized inverse electron demand hetero-Diels-Alder (IED HDA) reaction is reported herein. A self-dimerization of the exocyclic enone installed in the A-ring through a homo-HDA reaction was identified to exclusively give a dimeric ent-kaurane diterpenoid with the spirochroman core. Moreover, efficient cross-HDA cycloadditions of this enone with various vinyl ethers or vinyl sulfides, instead of its own homo-HDA dimerization, were achieved in a regio- and stereoselective manner, thus providing access to novel dihydropyran-fused diterpenoids as potential anticancer agents to overcome chemoresistance. PMID:25225052

Ding, Chunyong; Wang, Lili; Chen, Haijun; Wild, Christopher; Ye, Na; Ding, Ye; Wang, Tianzhi; White, Mark A; Shen, Qiang; Zhou, Jia



A remarkable regiocontrol in the palladium-catalyzed silylstannylation of fluoroalkylated alkynes--highly regio- and stereoselective synthesis of multi-substituted fluorine-containing alkenes.  


On treating fluorine-containing internal alkynes with 1.2 equiv. of (trimethylsilyl)tributyltin in the presence of 2.5 mol% of Pd(PPh3)2Cl2 in THF at the reflux temperature for 6 h, the silylstannylation reaction proceeded smoothly to afford the corresponding silylstannylated adducts in high yields in a highly regio- and cis-selective manner. Switching the palladium catalyst from Pd(PPh3)2Cl2 to Pd(t-BuNC)2Cl2 promoted the formation of silylstannylated adducts with opposite regioselectivity. The thus obtained silylstannylated adducts were subjected to Stille cross-coupling reactions to furnish the corresponding fluoroalkylated vinylsilanes whose C-Si bond was converted to a C-C bond by treating with aldehyde in the presence of TBAF and Zn(OTf)2, the corresponding fluoroalkylated tetra-substituted alkenes being afforded in moderate to good yields with a defined stereochemistry. PMID:24469343

Konno, Tsutomu; Kinugawa, Ryoko; Ishihara, Takashi; Yamada, Shigeyuki



Elucidation of the regio- and chemoselectivity of enzymatic allylic oxidations with Pleurotus sapidus - conversion of selected spirocyclic terpenoids and computational analysis  

PubMed Central

Summary Allylic oxidations of olefins to enones allow the efficient synthesis of value-added products from simple olefinic precursors like terpenes or terpenoids. Biocatalytic variants have a large potential for industrial applications, particularly in the pharmaceutical and food industry. Herein we report efficient biocatalytic allylic oxidations of spirocyclic terpenoids by a lyophilisate of the edible fungus Pleurotus sapidus. This ‘’mushroom catalysis’’ is operationally simple and allows the conversion of various unsaturated spirocyclic terpenoids. A number of new spirocyclic enones have thus been obtained with good regio- and chemoselectivity and chiral separation protocols for enantiomeric mixtures have been developed. The oxidations follow a radical mechanism and the regioselectivity of the reaction is mainly determined by bond-dissociation energies of the available allylic CH-bonds and steric accessibility of the oxidation site. PMID:24204436

Weidmann, Verena; Schaffrath, Mathias; Zorn, Holger



A green, multicomponent, regio- and stereo-selective 1,3-dipolar cycloaddition of azides and azomethine ylides generated in situ with bifunctional dipolarophiles using PEG-400.  


A series of novel dispiropyrrolidine-linked 1,2,3-triazole derivatives have been prepared by one-pot, four-component protocol that employed 5-arylidene-3-(prop-2-ynyl)thiazolidine-2,4-dione, isatin, sarcosine and substituted azides using Cu(I) generated in situ as catalyst in PEG-400 as a highly efficient and green media. This is the first report of a four-component reaction involving a classical Huisgen reaction, in which the two dipolar moieties (substituted azides and in situ generated azomethine ylides) react with acetylenic and olefinic dipolarophiles, respectively. The 1,3-dipolar cycloaddition proceeds in a highly regio- and stereo-selective manner. This methodology can be an ideal tool for the preparation of biologically important five-membered heterocyclic compounds in one pot. PMID:24577732

Sindhu, Jayant; Singh, Harjinder; Khurana, J M



Regio- and Stereospecific Hydroxylation of Various Steroids at the 16? Position of the D Ring by the Streptomyces griseus Cytochrome P450 CYP154C3  

PubMed Central

Cytochrome P450 monooxygenases (P450s), which constitute a superfamily of heme-containing proteins, catalyze the direct oxidation of a variety of compounds in a regio- and stereospecific manner; therefore, they are promising catalysts for use in the oxyfunctionalization of chemicals. In the course of our comprehensive substrate screening for all 27 putative P450s encoded by the Streptomyces griseus genome, we found that Escherichia coli cells producing an S. griseus P450 (CYP154C3), which was fused C terminally with the P450 reductase domain (RED) of a self-sufficient P450 from Rhodococcus sp., could transform various steroids (testosterone, progesterone, ?4-androstene-3,17-dione, adrenosterone, 1,4-androstadiene-3,17-dione, dehydroepiandrosterone, 4-pregnane-3,11,20-trione, and deoxycorticosterone) into their 16?-hydroxy derivatives as determined by nuclear magnetic resonance and high-resolution mass spectrometry analyses. The purified CYP154C3, which was not fused with RED, also catalyzed the regio- and stereospecific hydroxylation of these steroids at the same position with the aid of ferredoxin and ferredoxin reductase from spinach. The apparent equilibrium dissociation constant (Kd) values of the binding between CYP154C3 and these steroids were less than 8 ?M as determined by the heme spectral change, indicating that CYP154C3 strongly binds to these steroids. Furthermore, kinetic parameters of the CYP154C3-catalyzed hydroxylation of ?4-androstene-3,17-dione were determined (Km, 31.9 ± 9.1 ?M; kcat, 181 ± 4.5 s?1). We concluded that CYP154C3 is a steroid D-ring 16?-specific hydroxylase which has considerable potential for industrial applications. This is the first detailed enzymatic characterization of a P450 enzyme that has a steroid D-ring 16?-specific hydroxylation activity. PMID:24334658

Makino, Takuya; Katsuyama, Yohei; Otomatsu, Toshihiko; Misawa, Norihiko



Regio- and stereospecific hydroxylation of various steroids at the 16? position of the D ring by the streptomyces griseus cytochrome P450 CYP154C3.  


Cytochrome P450 monooxygenases (P450s), which constitute a superfamily of heme-containing proteins, catalyze the direct oxidation of a variety of compounds in a regio- and stereospecific manner; therefore, they are promising catalysts for use in the oxyfunctionalization of chemicals. In the course of our comprehensive substrate screening for all 27 putative P450s encoded by the Streptomyces griseus genome, we found that Escherichia coli cells producing an S. griseus P450 (CYP154C3), which was fused C terminally with the P450 reductase domain (RED) of a self-sufficient P450 from Rhodococcus sp., could transform various steroids (testosterone, progesterone, ?(4)-androstene-3,17-dione, adrenosterone, 1,4-androstadiene-3,17-dione, dehydroepiandrosterone, 4-pregnane-3,11,20-trione, and deoxycorticosterone) into their 16?-hydroxy derivatives as determined by nuclear magnetic resonance and high-resolution mass spectrometry analyses. The purified CYP154C3, which was not fused with RED, also catalyzed the regio- and stereospecific hydroxylation of these steroids at the same position with the aid of ferredoxin and ferredoxin reductase from spinach. The apparent equilibrium dissociation constant (Kd) values of the binding between CYP154C3 and these steroids were less than 8 ?M as determined by the heme spectral change, indicating that CYP154C3 strongly binds to these steroids. Furthermore, kinetic parameters of the CYP154C3-catalyzed hydroxylation of ?(4)-androstene-3,17-dione were determined (Km, 31.9 ± 9.1 ?M; kcat, 181 ± 4.5 s(-1)). We concluded that CYP154C3 is a steroid D-ring 16?-specific hydroxylase which has considerable potential for industrial applications. This is the first detailed enzymatic characterization of a P450 enzyme that has a steroid D-ring 16?-specific hydroxylation activity. PMID:24334658

Makino, Takuya; Katsuyama, Yohei; Otomatsu, Toshihiko; Misawa, Norihiko; Ohnishi, Yasuo



Highly regio- and diastereoselective, acidic clay supported intramolecular nitrile oxide-alkene cycloaddition on d-ribose derived nitriles: an efficient synthetic route to isoxazoline fused five and six membered carbocycles.  


An efficient synthetic route to isoxazoline fused carbocycles from carbohydrate scaffolds that comprise of free hydroxyl group(s) is described with high regio- and stereoselectivity. Montmorillonite K-10/chloramine T oxidation and in situ intramolecular nitrile oxide-alkene cycloaddition (INOC) of d-ribose derived oximes have been developed for the diversity oriented synthesis of isoxazoline fused five and six membered carbocycles. PMID:25238125

Panda, Amarendra; Das, Sulagna; Pal, Shantanu



[Health problems of the city of Split on the pages of the first newspaper written in Croatian language: "Il Regio Dalmata-Kraglski Dalmatin" (1806-1810): on the occasion of the 200th anniversary of termination of its publication].  


At the beginning of the 19th century, one of the most important cultural events in Dalmatia was the publication of a bilingual newspaper Il Regio Dalmata - Kraglski Dalmatin in Italian and Croatian, issued by the French government in Zadar between 12 July 1806 and 22 January 1808. Between 29 January 1808 and 1 April 1810 it changed name to Il Regio Dalmata. The journal paid much attention to the health problems of the city of Split, especially between 1806 and 1808. The aim of this study was to analyze the original articles published in this first newspaper in Croatian language and to understand the role of this publication as means of promoting health policies in Split. The journal published articles about health care for the poor and foundlings, about the need for charity institutions to refer them to the city hospital and to the foundling home, and encouraged citizens to help maintain these institutions. Great attention was also dedicated to vaccination against smallpox and demographic problems of Split. Thanks to Croatian, Il Regio Dalmata-Kraglski Dalmatin informed a wider audience about the existing health conditions in the city of Split and about the efforts of the French government for its improvement. PMID:21192116

Brisky, Livia



Interaction Between Radiating Graben-Fissure Systems and Local Geology, Ulfrun Regio, Venus: A Contribution to the Venus Global Dyke Swarm Map Project.  

NASA Astrophysics Data System (ADS)

This study is part of the larger Venus Global Dyke Swarm Map project, which has the goals of (1) producing a global map of graben-fissure systems, (2) assessing which systems are underlain by dyke swarms, and (3) contributing to the understanding of the tectonic and magmatic history of the planet. Graben-fissure systems on Venus are comprised of extensional lineaments, related to tectonic and/or magmatic activity. We are concentrating on the radiating systems (sometimes termed novae or radial fracture centres) which are of particular interest because they are largely ac-knowledged to be underlain by dyke swarms laterally emplaced from a magmatic centre located at the focus of the system [e.g., 1]. We have mapped the radiating graben fissure-systems in the Ulfrun Regio region of Venus using Magellan Synthetic Aperture Radar (SAR ) data at the highest resolution available (75 m/pixel). This area (200-240° E, 0-25° N) notably contains the western portion of the Hecate Chasma system, two large volcanoes (Ozza Mons and Nazit Mons), and a number of large coronae and novae. It also involves considerable deformation relating to extensional rifting and associated magmatic activity. In the Ulfrun Regio area, our mapping (over an area of 10.7 Mkm2) has identified 69 radiating systems, with diameters ranging from 20 km to greater than 2000 km. Many magmatic centres (at the foci of these radiating systems) are newly recognized, while others correspond to previously known coronae and volcanoes. We have found that it is not unusual for a single magmatic centre to exhibit multiple generations of radiating graben-fissure systems. Our graben-fissure mapping is compared with the new global geological map produced by M. Ivanov [1]. We are studying the manner in which large radiating graben-fissure systems interact with separate geological units. Radiating systems can be extensive; when crossing different geological units their surface expression varies and can manifest itself through changes in fracture density, definition, or fracture width. Radiating systems can be obscured in a geological unit and be visible in another unit, further from the presumed source. We hypothesize that these interactions are primarily a function of the relative ages of the systems with respect to the geological units, and thus that this approach can yield new information about the emplacement of individual systems and the relative ages of different magmatic centres. [1] Grosfils E. B. and Head J. W. (1994) Geophys. Res. Let., 21, 701-704. [2] Ivanov, M. A. (2008) LPSC XXXIX, abstract #1017.

Studd, Duncan; Ernst, Richard; Samson, Claire; Grosfils, Eric B.; Head, James W.; Ivanov, M. A.


The regio- and stereo-selective reduction of steroidal 4-en-3-ones using Na?S?O?/NaHCO? and CuCl/NaBH?.  


This paper describes the regio- and stereoselective reduction of ??-3-keto moiety in certain steroids using Na?S?O?/NaHCO? and CuCl/NaBH?, respectively. Using either one of the two reduction agents in the reaction, the 17-substituents in the D ring were observed to have clearly influenced the stereoselective reduction of 4-ene in the A ring by the so-called conformational transmission effect. Na?S?O?/NaHCO? regioselectively reduced CC at 4-position of 17-substituted-androst-4-en-3-one derivatives to 5?-H-3-one as the main isomer. And as an extended application, Epiandrosterone (11) was further synthesized from androst-4-en-3,17-dione (AD) via four steps. The total yield from this was about 45%. In the presence of CuCl/NaBH?, ??-3-keto conjugated reduction of 17-spirocyclic ethylene ketal protected androst-4-en-3-one derivatives mainly produced 3?-hydroxy-5?-H isomers, at a yield around 81%. Considering the scaffold configuration of 3?-hydroxy-5?-H moiety coincided with that of bile acid analogs, this selective reduction could also be used as an alternative method for the synthetic study of bile acids using AD and its derivatives, which are from the microorganism degradation of natural sterols, as the potential materials. Meanwhile, configurations of the reductive compounds 5b, 6b, 9, 10 and 17e were identified by X-ray diffraction. PMID:24128809

Wang, Chunli; Chen, Xiaoyu; Huang, Yaoqing; Yang, Jesse; Chen, Ying



Highly regio- and stereoselective acylboration, acylsilation, and acylstannation of allenes catalyzed by phosphine-free palladium complexes: an efficient route to a new class of 2-acylallylmetal reagents.  


A new method for the synthesis of substituted 2-acylallylmetal reagents in a highly regio- and stereoselective fashion involving a three-component assembly of allenes, acyl chlorides, and bimetallic reagents (B-B, Si-Si, and Sn-Sn) catalyzed by phosphine-free palladium complexes is described. Treatment of various allenes (CR(2)R(3)=C=CH(2)) with acyl chlorides (R(1)COCl) and bispinacolatodiboron in the presence of PdCl(2)(CH(3)CN)(2) in toluene at 80 degrees C gave 2-acylallylboronates in moderate to good yields. The acylsilation of allenes with acid chlorides and hexamethyldisilane (5) proceeded successfully in the presence of Pd(dba)(2) in CH(3)CN affording the corresponding allylsilanes (CR(2)R(3)=C(COR(1))CH(2)SiMe(3)) in good to moderate yields. Several chloroformates (R(4)OCOCl) also react with 1,1-dimethylallene (2a) and 5 to afford allylsilanes (CR(2)R(3)=C(COOR(4))CH(2)SiMe(3)) in 66-70% yields. Acylstannation of allenes could also be achieved by slow addition of hexabutylditin (10) to the reaction mixture of acyl chloride (or chloroformate) and allene 2a in CH(3)CN in the presence of Pd(dba)(2) at 60 degrees C; the corresponding 2-substituted allylstannanes were isolated in moderate to good yields. The above catalytic reactions are completely regioselective and highly stereoselective. A mechanism is proposed to account for the catalytic reactions and the stereochemistry. PMID:14531703

Yang, Feng-Yu; Shanmugasundaram, Muthian; Chuang, Shih-Yih; Ku, Po-Jen; Wu, Ming-Yuan; Cheng, Chien-Hong



Geologic map of the Bell Regio Quadrangle (V-9), Venus  

USGS Publications Warehouse

The Magellan spacecraft orbited Venus from August 10, 1990, until it plunged into the venusian atmosphere on October 12, 1994. Magellan had the objectives of (1) improving knowledge of the geologic processes, surface properties, and geologic history of Venus by analysis of surface radar characteristics, topography, and morphology and (2) improving knowledge of the geophysics of Venus by analysis of venusian gravity. The Magellan spacecraft carried a 12.6-cm radar system to map the surface of Venus. The transmitter and receiver systems were used to collect three datasets: synthetic aperture radar (SAR) images of the surface, passive microwave thermal emission observations, and measurements of the backscattered power at small angles of incidence, which were processed to yield altimetric data. Radar imaging and altimetric and radiometric mapping of the venusian surface were done in mission cycles 1, 2, and 3, from September 1990 until September 1992. Ninety-eight percent of the surface was mapped with radar resolution of approximately 120 meters. The SAR observations were projected to a 75-m nominal horizontal resolution; these full-resolution data compose the image base used in geologic mapping. The primary polarization mode was horizontal-transmit, horizontal-receive (HH), but additional data for selected areas were collected for the vertical polarization sense. Incidence angles varied from about 20° to 45°. High-resolution Doppler tracking of the spacecraft was done from September 1992 through October 1994 (mission cycles 4, 5, 6). High-resolution gravity observations from about 950 orbits were obtained between September 1992 and May 1993, while Magellan was in an elliptical orbit with a periapsis near 175 kilometers and an apoapsis near 8,000 kilometers. Observations from an additional 1,500 orbits were obtained following orbitcircularization in mid-1993. These data exist as a 75° by 75° harmonic field.

Campbell, Bruce A.; Campbell, Patricia G.



EM International. Volume 1  

SciTech Connect

It is the intent of EM International to describe the Office of Environmental Restoration and Waste Management`s (EM`s) various roles and responsibilities within the international community. Cooperative agreements and programs, descriptions of projects and technologies, and synopses of visits to international sites are all highlighted in this semiannual journal. Focus on EM programs in this issue is on international collaboration in vitrification projects. Technology highlights covers: in situ sealing for contaminated sites; and remote sensors for toxic pollutants. Section on profiles of countries includes: Arctic contamination by the former Soviet Union, and EM activities with Germany--cooperative arrangements.

Not Available



EMS in the pueblos.  


Imagine creating a movie by excerpting scenes from "Dances With Wolves," splicing it with footage from "Code 3" or "Emergency Response" and then flavoring the script with the mystery of a Tony Hillerman novel. A film producer would probably find it quite difficult to choreograph a finished product from such a compilation of material. To hundreds of Native American EMS providers, however, such a movie is played out every day in Indian country. And with this movie come some real-life problems, including trauma, which is the number-one cause of premature death among Native Americans. But a high trauma rate is just one of the challenges facing tribal EMS responders. There's also prolonged response and transport, the problems involved in maintaining the unique culture and standard of care, the challenges of tribal EMS administration and EMS education of Native American students, and the unsure future of Native American EMS. Beyond that, there's the fact that EMS is a s unique to each Indian reservation as are the cultures of the native peoples who reside on these lands. Yet while no two systems are alike, most tribal EMS providers face similar challenges. PMID:10131740

Vigil, M A



Environmental Media Services (EMS)  

NSDL National Science Digital Library

Environmental Media Services (EMS) is a nonprofit communications clearinghouse committed to the expansion of media coverage on critical environmental and public health issues. True to their mission, EMS staff "build relationships with top scientists, physicians, and other experts to bring journalists the latest and most credible information." EMS's modest homepage is free of clutter but full of content. While several sections are under construction and updates (currently) appear irregular, a series of available articles provides useful summaries of important environmental news issues over the past six months. Current articles include "The impacts of global warming on the oceans" and "Cool companies," among others.


EM Radiation Program  

NSDL National Science Digital Library

The EM Radiation program displays the electric field vectors (in the x-y plane) and magnetic field contours (for the field in the z direction) calculated from the Lienard-Wiechert potentials for a charged particle. The default scenario shows the resulting radiation from a charged particle in simple harmonic motion. Additional particle trajectories can be specified using the Display | Switch GUI menu item. EM Radiation is an Open Source Physics program written for the teaching of electromagnetism. It is distributed as a ready-to-run (compiled) Java archive. Double clicking the em_radiation.jar file will run the program if Java is installed. Other electromagnetism programs are also available. They can be found by searching ComPADRE for Open Source Physics, OSP, or electromagnetism.

Christian, Wolfgang



The EM Earthquake Precursor  

NASA Astrophysics Data System (ADS)

Many attempts have been made to determine a sound forecasting method regarding earthquakes and warn the public in turn. Presently, the animal kingdom leads the precursor list alluding to a transmission related source. By applying the animal-based model to an electromagnetic (EM) wave model, various hypotheses were formed, but the most interesting one required the use of a magnetometer with a differing design and geometry. To date, numerous, high-end magnetometers have been in use in close proximity to fault zones for potential earthquake forecasting; however, something is still amiss. The problem still resides with what exactly is forecastable and the investigating direction of EM. After the 1989 Loma Prieta Earthquake, American earthquake investigators predetermined magnetometer use and a minimum earthquake magnitude necessary for EM detection. This action was set in motion, due to the extensive damage incurred and public outrage concerning earthquake forecasting; however, the magnetometers employed, grounded or buried, are completely subject to static and electric fields and have yet to correlate to an identifiable precursor. Secondly, there is neither a networked array for finding any epicentral locations, nor have there been any attempts to find even one. This methodology needs dismissal, because it is overly complicated, subject to continuous change, and provides no response time. As for the minimum magnitude threshold, which was set at M5, this is simply higher than what modern technological advances have gained. Detection can now be achieved at approximately M1, which greatly improves forecasting chances. A propagating precursor has now been detected in both the field and laboratory. Field antenna testing conducted outside the NE Texas town of Timpson in February, 2013, detected three strong EM sources along with numerous weaker signals. The antenna had mobility, and observations were noted for recurrence, duration, and frequency response. Next, two directional techniques were employed, resulting in three mapped, potential epicenters. The remaining, weaker signals presented similar directionality results to more epicentral locations. In addition, the directional results of the Timpson field tests lead to the design and construction of a third prototype antenna. In a laboratory setting, experiments were created to fail igneous rock types within a custom-designed Faraday Cage. An antenna emplaced within the cage detected EM emissions, which were both reproducible and distinct, and the laboratory results paralleled field results. With a viable system and continuous monitoring, a fracture cycle could be established and observed in real-time. Sequentially, field data would be reviewed quickly for assessment; thus, leading to a much improved earthquake forecasting capability. The EM precursor determined by this method may surpass all prior precursor claims, and the general public will finally receive long overdue forecasting.

Jones, K. B., II; Saxton, P. T.



Carcinoma espinocelular cutâneo em cães.  

E-print Network

??Dissertação de Mestrado Integrado em Medicina Veterinária O Carcinoma Espinocelular (CEC) é uma neoplasia com origem nos queratinócitos e representa aproximadamente 5% das neoplasias cutâneas… (more)

Moura, Inês da Costa



Identified EM Earthquake Precursors  

NASA Astrophysics Data System (ADS)

Many attempts have been made to determine a sound forecasting method regarding earthquakes and warn the public in turn. Presently, the animal kingdom leads the precursor list alluding to a transmission related source. By applying the animal-based model to an electromagnetic (EM) wave model, various hypotheses were formed, but the most interesting one required the use of a magnetometer with a differing design and geometry. To date, numerous, high-end magnetometers have been in use in close proximity to fault zones for potential earthquake forecasting; however, something is still amiss. The problem still resides with what exactly is forecastable and the investigating direction of EM. After a number of custom rock experiments, two hypotheses were formed which could answer the EM wave model. The first hypothesis concerned a sufficient and continuous electron movement either by surface or penetrative flow, and the second regarded a novel approach to radio transmission. Electron flow along fracture surfaces was determined to be inadequate in creating strong EM fields, because rock has a very high electrical resistance making it a high quality insulator. Penetrative flow could not be corroborated as well, because it was discovered that rock was absorbing and confining electrons to a very thin skin depth. Radio wave transmission and detection worked with every single test administered. This hypothesis was reviewed for propagating, long-wave generation with sufficient amplitude, and the capability of penetrating solid rock. Additionally, fracture spaces, either air or ion-filled, can facilitate this concept from great depths and allow for surficial detection. A few propagating precursor signals have been detected in the field occurring with associated phases using custom-built loop antennae. Field testing was conducted in Southern California from 2006-2011, and outside the NE Texas town of Timpson in February, 2013. The antennae have mobility and observations were noted for recurrence, duration, and frequency response. At the Southern California field sites, one loop antenna was positioned for omni-directional reception and also detected a strong First Schumann Resonance; however, additional Schumann Resonances were absent. At the Timpson, TX field sites, loop antennae were positioned for directional reception, due to earthquake-induced, hydraulic fracturing activity currently conducted by the oil and gas industry. Two strong signals, one moderately strong signal, and approximately 6-8 weaker signals were detected in the immediate vicinity. The three stronger signals were mapped by a biangulation technique, followed by a triangulation technique for confirmation. This was the first antenna mapping technique ever performed for determining possible earthquake epicenters. Six and a half months later, Timpson experienced two M4 (M4.1 and M4.3) earthquakes on September 2, 2013 followed by a M2.4 earthquake three days later, all occurring at a depth of five kilometers. The Timpson earthquake activity now has a cyclical rate and a forecast was given to the proper authorities. As a result, the Southern California and Timpson, TX field results led to an improved design and construction of a third prototype antenna. With a loop antenna array, a viable communication system, and continuous monitoring, a full fracture cycle can be established and observed in real-time. In addition, field data could be reviewed quickly for assessment and lead to a much more improved earthquake forecasting capability. The EM precursors determined by this method appear to surpass all prior precursor claims, and the general public will finally receive long overdue forecasting.

Jones, Kenneth, II; Saxton, Patrick



College of Engineering EM Engineering Mechanics  

E-print Network

College of Engineering EM Engineering Mechanics KEY: # = new course * = course changed = course or concur: MA 213. EM 302 MECHANICS OF DEFORMABLE SOLIDS. (3 of Engineering or consent of chairperson, and EM 221; prereq or concur: MA 214. EM 313 DYNAMICS. (3

MacAdam, Keith


Investimento ambiental em indústrias sujas e intensivas em recursos naturais e energia  

Microsoft Academic Search

O crescimento industrial brasileiro, a partir do final dos anos setenta, ocorreu com o aumento da participação de indústrias intensivas em recursos naturais, em detrimento da participação de indústrias intensivas em trabalho e dos setores intensivos em atividades tecnológicas mais complexas. Essas transformações, tornando o setor de bens intermediários dominante na estrutura industrial, implicaram em consideráveis mudanças tanto de ordem

Frederico Cavadas Barcellos; Jurandir Carlos de Oliveira; Paulo Gonzaga Mibielli de Carvalho



Turismo Náutico em Angra dos Reis – RJ : a sustentabilidade em questão.  

E-print Network

??Dissertação (mestrado)—Universidade de Brasília, Centro de Desenvolvimento Sustentável, 2011. O turismo está em franca expansão e se desenvolvendo a taxas bastante significativas no Brasil. Em… (more)

Medeiros, Márcio Bastos



Populações estelares em galáxias HII  

NASA Astrophysics Data System (ADS)

Analisamos o conteúdo estelar de 74 galáxias HII a partir do contínuo observado nos espectros ópticos dessas galáxias, utilizando métodos de síntese de população estelar. Descobrimos que todas as galáxias para as quais encontramos soluções contêm uma população estelar velha que domina a massa estelar, e numa maioria dessas também encontramos evidência de uma população de idade intermediaria além da geração jovem que está se formando agora. Concluímos que a formação estelar dessas galáxias se realiza em surtos individuais, Esses surtos são interrompidos por longos períodos de inatividade, com os primeiros consumindo a maior parte do gás. Sugerimos, portanto, que as galáxias HII sejam galáxias anãs normais flagradas em um período de surto.

Westera, P.; Cuisinier, F.; Telles, E.; Kehrig, C.



Burning the EMS candle. EMS shifts and worker fatigue.  


Has coffee become your best friend? Do you sleep only in your dreams? Is your bed merely an illusion? If so, you are not alone; sleep deprivation is a fact of life for many EMS personnel. Though widely accepted, isn't it time that we question the effects of those long days and nights? PMID:10116022

McCallion, R; Fazackerley, J



Programa de Ps-Graduao em Economia  

E-print Network


Maier, Rudolf Richard


The European Mobile System (EMS)  

NASA Technical Reports Server (NTRS)

The European Space Agency is presently procuring an L band payload in order to promote a regional European L band system coping with the specific needs of the European market. The payload, and the two communications systems to be supported, are described below. The potential market for EMS in Europe is discussed.

Jongejans, A.; Rogard, R.; Mistretta, I.; Ananasso, F.



WRF-EMS Aviation Products  

NSDL National Science Digital Library

This lesson illustrates how numerical guidance from the Weather Research and Forecasting Model - Environmental Modeling System (WRF-EMS) can be added to surface observations, satellite graphics, and conceptual models of important aviation phenomena, to produce TAFs. Specifically, the lesson describes how visibility, cloud ceilings, and the flight categories variables provide values for aviation forecasts in Africa.




Angus Robichaud's Reel G Em D A Bm D7  

E-print Network

Angus Robichaud's Reel 4 4 D G A D D G A D 3 3 G Em D A Bm D7 3 3 G Em D A D Animas Reel Bernie Waugh 4 4 3 3 G D G Bm Em C Am C D G D G Bm Em C Am D G The Arkansas Traveler 4 2 D G A D Em A 3D G A D Em G A D D G D A Bm Em A D G D A Em G A D #12;Asher Rodney Miller 4 4 D Em F#m G A D Em G A D A D1 2

Doyle, Peter


Angus Robichaud's Reel G Em D A Bm D7  

E-print Network

Angus Robichaud's Reel 4 4 D G A D D G A D 3 3 G Em D A Bm D7 3 3 G Em D A D Animas Reel Bernie Waugh 4 4 3 3 G D G Bm Em C Am C D G D G Bm Em C Am D G The Arkansas Traveler 4 2 D G A D Em A 3 D G A D Em G A D D G D A Bm Em A D G D A Em G A D #12; Asher Rodney Miller 4 4 D Em F#m G A D Em G A D A D 1

Doyle, Peter


Regio- and stereochemistry of 1,3-dipolar cycloaddition of nitrile oxides to alkenes  

NASA Astrophysics Data System (ADS)

The published data on the chemistry of intermolecular 1,3-dipolar cycloaddition of nitrile oxides to different types of alkene derivatives are systematised. Various aspects of stereo- and regiochemistry of this reaction are considered. The bibliography includes 182 references.

Litvinovskaya, Raisa P.; Khripach, Vladimir A.



Modeling of biliverdin reduction process: regio-specificity and H-bonding  

NASA Astrophysics Data System (ADS)

Octa ethyl biliverdin (OEBV) has been employed as a model for natural biliverdin and its geometry has been optimized by using semiempirical (AM1, PM3), DFT, and hybrid ONIOM methods. Geometries and energetics of formation of octa ethyl bilirubin (OEBR) formed by reduction from OEBV via three carbon sites ?, ?, and ? have been obtained. It has been shown that ?-OEBR has two configurational isomers (named ? 1 and ? 2), which can convert to each other by internal 1,5-hydrogen shift. The results show that, within the accuracy level of semiempirical methods, all three isomers namely, ?, ? 1, and ?-OEBR are of similar stability whereas, at higher level of theory, ? 1-OEBR is less stable than others. Moreover, ? 2-isomer with one more of its pyrrole rings being aromatic can achieve a higher symmetry, and is the most stable among others by at least 5-6 kcal mol -1 based on various methods employed. It is interesting to note that the ridge-tile conformation, which has been confirmed for natural bilirubin was not observed for calculated geometries of ? 1- and ? 2-isomers. A conformational analysis show that an energy barrier of ˜25 kcal mol -1 must be surmounted for ? 2 to obtain the ridge-tile geometry. OEBV was synthesized and purified from octa ethyl porphyrin iron (III) chloride, and was reduced to OEBR by sodium borohydride (NaBH 4). Chemical reduction of OEBV with NaBH 4 was followed in CDCl 3 and CD 3OD solutions and the product was characterized by 1H NMR and UV-Vis spectroscopy. The results show that ? 2-isomer as the major product, forms along with ? 1 via an equilibrium tautomerization reaction.

Zahedi, Mansour; Ghiasi, Mina; Safari, Nasser



Using NMR to Probe the Regio- and Stereochemistry of the Hydration of 1-Hexene  

ERIC Educational Resources Information Center

This undergraduate organic laboratory experiment complements previously described and popular experiments on hydration of 1-hexene where students experimentally establish the Markovnikov regioselectivity of alkene hydration. In this experiment, students explore not only the regiochemistry but also the stereochemistry of 1-hexene hydration and…

Saba, Shahrokh; Clarke, Donald D.; Iwanoski, Christa; Lobasso, Thomas



Confining phosphanes derived from cyclodextrins for efficient regio- and enantioselective hydroformylation.  


Two confining phosphane ligands derived from either ?- or ?-cyclodextrin produce singly P(III) -ligated metal complexes with unusual coordination spheres. High-pressure NMR studies have revealed that rhodium hydride complexes of the same type are also formed under hydroformylation conditions. This unique feature strongly favors the formation of the branched aldehyde at the expense of the linear one with high enantioselectivity in the rhodium-catalyzed hydroformylation of styrene. PMID:24590681

Jouffroy, Matthieu; Gramage-Doria, Rafael; Armspach, Dominique; Sémeril, David; Oberhauser, Werner; Matt, Dominique; Toupet, Loic



Application of immobilized lipase to regio-specific interesterification of triglyceride in organic solvent  

Microsoft Academic Search

Lipase from Rhizopus delemar was immobilized by entrapment with photo-crosslinkable resin prepolymers or urethane prepolymers or by binding to various types of porous silica beads. The immobilized lipase preparations thus obtained were examined for their activity in converting olive oil to an interesterified fat (cacao butter-like fat), whose oleic acid moieties at 1- and 3-positions were replaced with stearic acid

Kenzo Yokozeki I; Shigeru Yamanaka; Koichi Takinami I; Yoshio Hirose; Atsuo Tanaka; Kenji Sonomoto; Saburo Fukui



Regio- and stereoselective access to novel ring-condensed steroidal isoxazolines.  


Novel 5?-androstanes containing an isoxazoline moiety condensed to ring A or D were efficiently synthetized by 1,3-dipolar cycloadditions of aryl nitrile oxides to steroidal ?,?-unsaturated ketones. During the ring closures, regioisomers in which the O terminus of the nitrile oxide dipoles is attached to the ?-carbon of the dipolarophile were formed in a stereoselective manner to furnish exclusively 1?,2?- or 15?,16?-condensed heterocycles. The cyclic enone moiety of the six-membered ring A proved to be less reactive than that of the five-membered ring D, but all the reactions were affected significantly by the substitution pattern of the nitrile oxide. 17-Deacetylation of the primary products resulted in aromatization or simultaneous hydroxylation, depending on the base applied for the ring A-fused heterocycles, while retro-Dieckmann-like fragmentation was observed partially or completely for the ring D-fused analogues during 3-deacetylation. PMID:24928722

Mótyán, Gerg?; Kádár, Zalán; Kovács, Dóra; Wölfling, János; Frank, Éva




E-print Network


Milano-Bicocca, Università


Total synthesis of tetrahydrolipstatin and stereoisomers via a highly regio- and diastereoselective carbonylation of epoxyhomoallylic alcohols.  


A concise enantioselective synthesis of tetrahydrolipstatin (THL) and seven stereoisomers has been achieved. The synthesis of THL was accomplished in 10 steps and 31% overall yield from an achiral ynone. Key to the success of the approach is the use of a bimetallic [Lewis acid](+)[Co(CO)4](-) catalyst for a late-stage regioselective carbonylation of an enantiomerically pure cis-epoxide to a trans-?-lactone. The success of this route to THL and its stereoisomers also demonstrated the practicality of the carbonylation catalyst for complex molecule synthesis as well as its functional group compatibility. PMID:25004122

Mulzer, Michael; Tiegs, Brandon J; Wang, Yanping; Coates, Geoffrey W; O'Doherty, George A



Regio- and stereoselective oxygenation of proline derivatives by using microbial 2-oxoglutarate-dependent dioxygenases.  


We evaluated the substrate specificities of four proline cis-selective hydroxylases toward the efficient synthesis of proline derivatives. In an initial evaluation, 15 proline-related compounds were investigated as substrates. In addition to l-proline and l-pipecolinic acid, we found that 3,4-dehydro-l-proline, l-azetidine-2-carboxylic acid, cis-3-hydroxy-l-proline, and l-thioproline were also oxygenated. Subsequently, the product structures were determined, revealing cis-3,4-epoxy-l-proline, cis-3-hydroxy-l-azetidine-2-carboxylic acid, and 2,3-cis-3,4-cis-3,4-dihydroxy-l-proline. PMID:25130741

Hara, Ryotaro; Uchiumi, Naoko; Okamoto, Naoko; Kino, Kuniki



Synthesis of new pentacyclic chromophores through a highly regio- and diastereoselective cascade process.  


A new family of pentacyclic compounds incorporating a central 1,2-dihydropyridine core is obtained through a pseudo three-component reaction. Four new bonds and two stereocenters with trans relationship are produced during the cascade process under palladium catalysis. PMID:20844800

Chamas, Zein el abidine; Dietz, Olivier; Aubert, Emmanuel; Fort, Yves; Mamane, Victor



One-pot chemo-, regio-, and stereoselective double-differential glycosidation mediated by lanthanide triflates.  


Nuanced activation of n-pentenyl, thioglycoside, and trichloroacetimidate donors by lanthanide salts coupled with donor/acceptor matching can simplify oligosaccharide assembly. Thus, a one-pot, double-differential glycosidation process can be designed, in which an n-pentenyl acceptor-diol is chemo- and regioselectively glycosidated by using an n-pentenyl ortho ester under the agency of Yb(OTf)(3)/NIS followed by in situ addition of a 2-O-acylated trichloroacetimidate or ethyl thioglycoside to effect stereoselective glycosidation at the remaining OH. PMID:15524445

Jayaprakash, K N; Fraser-Reid, Bert



Regio-selective chemical-enzymatic synthesis of pyrimidine nucleotides facilitates RNA structure and dynamics studies.  


Isotope labeling has revolutionized NMR studies of small nucleic acids, but to extend this technology to larger RNAs, site-specific labeling tools to expedite NMR structural and dynamics studies are required. Using enzymes from the pentose phosphate pathway, we coupled chemically synthesized uracil nucleobase with specifically (13) C-labeled ribose to synthesize both UTP and CTP in nearly quantitative yields. This chemoenzymatic method affords a cost-effective preparation of labels that are unattainable by current methods. The methodology generates versatile (13) C and (15) N labeling patterns which, when employed with relaxation-optimized NMR spectroscopy, effectively mitigate problems of rapid relaxation that result in low resolution and sensitivity. The methodology is demonstrated with RNAs of various sizes, complexity, and function: the exon splicing silencer 3 (27 nt), iron responsive element (29 nt), Pro-tRNA (76 nt), and HIV-1 core encapsidation signal (155 nt). PMID:24954297

Alvarado, Luigi J; LeBlanc, Regan M; Longhini, Andrew P; Keane, Sarah C; Jain, Niyati; Yildiz, Zehra F; Tolbert, Blanton S; D'Souza, Victoria M; Summers, Michael F; Kreutz, Christoph; Dayie, T Kwaku



A Rh-catalyzed regio- and stereoselective route to enamides: benzamides as assembling reagents.  


A new protocol for the synthesis of fully substituted enaminones has been achieved using a diverse range of benzamides and 1-sulfonyl-1,2,3-triazoles. Selective removal of the ?-amino moiety of the obtained ?-amido-enaminones to form Z-enamides was also demonstrated thus improving the synthetic value of benzamides for structural diversities in a minimum number of synthetic steps. PMID:24824297

Lee, Dong Jin; Shin, Jinhwan; Yoo, Eun Jeong




E-print Network

DEPARTAMENTO DE ECONOMIA MESTRADO EM ECONOMIA EDITAL DE CONVOCA��O ­ 2014 Estão abertas as inscrições para o Mestrado em Economia da PUC-Rio, a iniciar-se em janeiro de 2014. Para candidatos residentes no Brasil: A admissão é feita através do Exame Nacional de Economia, organizado pela ANPEC



E-print Network

DEPARTAMENTO DE ECONOMIA DOUTORADO EM ECONOMIA EDITAL DE CONVOCA��O ­ 2014 Estão abertas as inscrições para o Doutorado em Economia da PUC-Rio, a iniciar-se em janeiro de 2014. O período de inscrições ]: Departamento de Economia [ref.: Candidatura ao Doutorado] Pontifícia Universidade Católica do Rio de Janeiro


Lietuvos teritorijos žem?s plutos deformacij? ir seismotektoninio potencialo ryšys  

NASA Astrophysics Data System (ADS)

Lietuvoje yra statini?, kelian?i? ekologinio pavojaus gr?sm? (Ignalinos atomin? elektrin?, Mažeiki? naftos perdirbimo ?mon?, chemijos gamyklos Jonavoje bei K?dainiuose ir pan.). Seisminiai ?vykiai gali sutrikdyti ši? ?moni? veikl? ir net lemti didel? pavoj? aplinkai, t. y. gali b?ti sukelta didel? aplinkos tarša chemin?mis bei radioaktyviosiomis medžiagomis. Seisminius ?vykius lemia teritorijos seismotektoninis potencialas. Seismotektoninis potencialas ir Žem?s plutos deformacijos yra tarpusavyje susij? rei\\vskiniai, kuriuos sukelia dažnai tie patys giluminiai procesai Žem?s gelm?se. Žem?s plutos deformacij? tyrimas yra vienas iš informacijos šaltini? prognozuojant teritorijos seismotektonin? aktyvum?. Straipsnyje nagrin?jamos Žem?s plutos horizontaliosios deformacijos, nustatomi Žem?s plutos ?tempi? poky?iai Lietuvos teritorijoje pagal GPS matavim? duomenis. Atlikus tyrimus pagal pateikiam? Žem?s plutos horizontali?j? deformacij? ir ?tempi? tyrimo metodik?, gauti nauji horizontali?j? deformacij? charakteristik? bei ?tempi? poky?i? rezultatai ir nustatytos j? s?sajos su seismotektoniniu potencialu.

Zakarevi?ius, Algimantas; Stanionis, Arminas; Levinskait?, Daiva



7 CFR 1945.20 - Making EM loans available.  

Code of Federal Regulations, 2012 CFR

...2012-01-01 false Making EM loans available. 1945.20 Section 1945.20 Agriculture Regulations of the Department...CONTINUED) EMERGENCY Disaster Assistance-General § 1945.20 Making EM loans available. EM...



EMS communications development: History and commentary  

Microsoft Academic Search

The history of emergency medical services (EMS) communication systems development from the FCC's first allocation of frequencies for hospitals and ambulances up to the present is discussed. Up until the late 1960's EMS communication systems were virtually nonexistent. Most early networks were developed by hospital associations for coordination of hospital disaster operations. Many significant changes were seeded in 1966. By

B. A. Smith



School Budget Hold'em Facilitator's Guide  

ERIC Educational Resources Information Center

"School Budget Hold'em" is a game designed to help school districts rethink their budgeting process. It evolved out of Education Resource Strategies' (ERS) experience working with large urban districts around the country. "School Budget Hold'em" offers a completely new approach--one that can turn the budgeting process into a long-term visioning…

Education Resource Strategies, 2012



EM international activities. February 1997 highlights  

SciTech Connect

EM International Highlights is a brief summary of on-going international projects within the Department of Energy`s Office of Environmental Management (EM). This document contains sections on: Global Issues, activities in Western Europe, activities in central and Eastern Europe, activities in Russia, activities in Asia and the Pacific Rim, activities in South America, activities in North America, and International Organizations.




Contributo para a caracterização molecular de echinococcus granulosus em Portugal.  

E-print Network

??Mestrado em Ciências Biomédicas, Especialidade de Biologia Molecular em Medicina Tropical e Internacional A Equinococose/hidatidose – doença causada pela fase larvar (hidátide – vulgarmente conhecida… (more)

Beato, Sílvia Filipa Alves



Project X RFQ EM Design  

SciTech Connect

Project X is a proposed multi-MW proton facility at Fermi National Accelerator Laboratory (FNAL). The Project X front-end would consist of an H- ion source, a low-energy beam transport (LEBT), a CW 162.5 MHz radio-frequency quadrupole (RFQ) accelerator, and a medium-energy beam transport (MEBT). Lawrence Berkeley National Laboratory (LBNL) and FNAL collaboration is currently developing the designs for various components in the Project X front end. This paper reports the detailed EM design of the CW 162.5 MHz RFQ that provides bunching of the 1-10 mA H- beam with acceleration from 30 keV to 2.1 MeV.

Romanov, Gennady; /Fermilab; Hoff, Matthew; Li, Derun; Staples, John; Virostek, Steve; /LBNL



EM International, July 1994, Volume 2  

SciTech Connect

The Office of Environmental Management (EM) at the Department of Energy (DOE) is seeking out and leveraging foreign technology, data, and resources in keeping with EM`s mandate to protect public health and the environment through the safe and cost-effective remediation of the Department`s nuclear weapons sites. EM works closely with foreign governments, industry, and universities to obtain innovative environmental technologies, scientific and engineering expertise, and operations experience that will support EM`s objectives. Where appropriate, these international resources are used to manage the more urgent risks at our sites, secure a safe workplace, help build consensus on critical issues, and strengthen our technology development program. Through international agreements EM engages in cooperative exchange of information, technology, and individuals. Currently, we are managing agreements with a dozen countries in Europe, Latin America, and Asia. These agreements focus on environmental restoration, waste management, transportation of radioactive wastes, and decontamination and decommissioning. This publication contains the following articles: in situ remediation integrated program; in-situ characterization and inspection of tanks; multimedia environmental pollutant assessment system (MEPAS); LLNL wet oxidation -- AEA technology. Besides these articles, this publication covers: EU activities with Russia; technology transfer activities; and international organization activities.

Not Available



Kinesiology Undergraduate Student Learning Outcomes (EMS)  

E-print Network

1 Kinesiology Undergraduate Student Learning Outcomes (EMS) Kinesiology Undergraduate Student Learning Outcomes (PE) Kinesiology Graduate Program 1. Students will demonstrate knowledge of and skill sociocultural, historical, and philosophical perspectives on kinesiology. 4. Students will understand how motor


Structural Composites with Tuned EM Chirality.  

National Technical Information Service (NTIS)

We have developed and implemented methods to predict the overall EM properties tensors including the coupling tensors based on the geometry and microstructure of an array of scattering elements, and fabricated and measured both the HM and mechanical prope...

S. Nemat-Nasser



Sincronizao em Sistemas Distribudos problemas clssicos  

E-print Network

problema de coordenação distribuída #12;ordenação de mensagens · implementação ­ uso de uma fila de holdback em camada de comunicação chegada de mensagens processamento (aplicação) fila entrega fila holdback destinatário responde com uma proposta de número de ordem ­ e deixa (msg, id_único, num_ordem_proposto) em fila

Rodriguez, Noemi


Condições físicas em galáxias HII  

NASA Astrophysics Data System (ADS)

Galáxias HII são galáxias anãs de baixa luminosidade que apresentam alta taxa de formação estelar. Seus espectros são dominados por intensas linhas de emissão devido à fotoionização pela presença de um grande número de estrelas do tipo O e B. Nós apresentamos um catálogo espectrofotométrico de 111 galáxias HII observadas no telescópio 1.52m do ESO com o espectrógrafo Boller & Chivens. Determinamos propriedades estatísticas da amostra e derivamos condições físicas (temperatura eletrônica, densidade eletrônica) e abundâncias químicas. Para algumas galáxias, fomos também capazes de resolver espacialmente regiões de formação estelar individuais e determinar propriedades espectroscópicas para estas regiões separadamente, o que nos permitiu avaliar as flutuações das condições físico-químicas dentro das galáxias HII. Em particular, vimos que apesar das galáxias HII apresentarem formação estelar espalhada ao longo do corpo da galáxia, são objetos quimicamente homogêneos. A fim de estudar a evolução temporal dos objetos durante o tempo de vida das estrelas ionizantes construimos também alguns diagramas relacionando razões de linhas de emissão com a largura equivalente de Hb (EW(Hb)). Para interpretar tais diagramas utilizamos modelos de fotoionização para populações estelares integradas. Concluímos que as galáxias HII não correspondem a simples idéia de um burst instantâneo envolvido por um gás opaco aos fótons ionizantes e com densidade constante. As relações observadas entre razões de linhas e EW(Hb) podem ser melhor compreendidas se as galáxias HII apresentarem populações estelares mais velhas, que contribuem para o contínuo óptico observado.

Kehrig, C.; Telles, E.; Cuisinier, F.




Microsoft Academic Search

As relações de gênero constituem o conjunto das relações sociais e econômicas no universo do trabalho, da cultura e da política. Está organizada a partir dos papéis masculinos e femininos dentro de estruturas que permanecem constantes em algumas sociedades ou de forma presente no inconsciente social que às vezes é refletido em ações do cotidiano colocando cada agente social dentro

Albejamere Pereira de Castro


SOFIS FTS EM test results  

NASA Astrophysics Data System (ADS)

The Solar Occultation FTS for Inclined-orbit Satellite (SOFIS) is a solar occultation Fourier transform spectrometer developed by the Ministry of the Environment (MOE) in Japan for the Global Change Observation Mission-A1 (GCOM-A1) satellite. GCOM-A1 will be placed in a 650 km non-sun-synchronous orbit, with an inclination angle of 69 degrees. ABB-Bomem is a sub-contractor of NTSpace (NEC-Toshiba Space) for the design and manufacturing of the FTS Engineering Model of SOFIS. SOFIS measures the vertical profile of the atmospheric constituents with 0.2 cm-1 spectral resolution for the spectral range covering 3-13 ?m. The atmospheric vertical resolution of SOFIS is 1 km. The target of SOFIS measurements is a global distribution of O3, HNO3, NO2, N2O, CH4, H2O, CO2, CFC-11, CFC-12, ClONO2, aerosol extinction, atmospheric pressure and temperature. NTSpace in Japan is the prime contractor of SOFIS. The spectrometer is an adapted version of the classical Michelson interferometer using an optimized optical layout and moving retro-reflectors. A solid-state laser diode operating at 1550 nm is used as metrology source of the interferometer. Its highly folded optical design results in a high performance instrument with a compact size. SOFIS FTS implements high performance control techniques to achieve outstanding speed stability of the moving mechanism. This paper describes the test activities of the SOFIS-FTS Engineering Model (EM) and preliminary results. The performances of the FTS are presented in terms of key parameters like signal-to-noise ratio, modulation efficiency and stability. Spectra acquired are shown and test methodology and analyses are presented. Lessons learned during assembly, integration and testing are described as well as improvements planned to be implemented in the Flight Model.

Soucy, Marc-Andre A.; Levesque, Luc E.; Tanii, Jun; Kawashima, Takahiro; Nakajima, Hideaki



Tour of the Electromagnetic Spectrum (EMS) Videos  

NSDL National Science Digital Library

These videos introduce middle- and high school-age learners to the electromagnetic spectrum. The product consists of 8 animations including an introduction to electromagnetic waves and one animation for each wavelength of the EM spectrum (Radio, Microwave, Infrared, Visible, Ultraviolet, X-Rays and Gamma Rays). Each wavelength of the EM spectrum offers a construct to illustrate and teach about NASA sensors, missions, and science. Emphasis is placed on relevant science, such as lunar exploration, and hot science topics, such as climate change. The examples and narrative for each wavelength animation build on the learnersâ prior knowledge then introduces examples from NASA missions. These examples explore the use of spectral analysis and visualizations that help scientists make discoveries about the world around us using EM waves.

Benesch, Troy



Risk Communication Within the EM Program  

SciTech Connect

The U.S. Department of Energy Environmental Management program (EM) conducts the most extensive environmental remediation effort in the world. The annual EM budgets have exceeded $6,000,000,000 for approximately ten years and EM has assumed responsibility for the cleanup of the largest DOE reservations (i.e., at Hanford, Washington, Aiken, South Carolina, and Idaho Falls, Idaho) as well as the facilities at Rocky Flats, Colorado and in Ohio. Each of these sites has areas of extensive radioactive and chemical contamination, numerous surplus facilities that require decontamination and removal, while some have special nuclear material that requires secure storage. The EM program has been criticized for being ineffective (1) and has been repeatedly reorganized to address perceived shortcomings. The most recent reorganization was announced in 2001 to become effective at the beginning of the 2003 Federal Fiscal Year (i.e., October 2002). It was preceded by a ''top to bottom'' review (TTBR) of the program (2) that identified several deficiencies that were to be corrected as a result of the reorganization. One prominent outcome of the TTBR was the identification of ''risk reduction'' as an organizing principle to prioritize the activities of the new EM program. The new program also sought to accelerate progress by identifying a set of critical activities at each site that could be accelerated and result in more rapid site closure, with attendant risk, cost, and schedule benefits. This paper investigates how the new emphasis on risk reduction in the EM program has been communicated to EM stakeholders and regulators. It focuses on the Rocky Flats Environmental Technology Site (RFETS) as a case study and finds that there is little evidence for a new emphasis on risk reduction in EM communications with RFETS stakeholders. Discussions between DOE and RFETS stakeholders often refer to ''risk,'' but the word serves as a placeholder for other concepts. Thus ''risk'' communication at RFETS is lively and involves important issues, but often does not inform participants about true ''risk reduction.''

Edelson, M.



7 CFR 1945.35 - Special EM loan training.  

Code of Federal Regulations, 2012 CFR

...2012-01-01 false Special EM loan training. 1945.35 Section 1945.35 Agriculture Regulations of the Department...CONTINUED) EMERGENCY Disaster Assistance-General § 1945.35 Special EM loan training. (a)...



7 CFR 1945.35 - Special EM loan training.  

Code of Federal Regulations, 2010 CFR

...2009-01-01 true Special EM loan training. 1945.35 Section 1945.35 Agriculture Regulations of the Department...CONTINUED) EMERGENCY Disaster Assistance-General § 1945.35 Special EM loan training. (a)...



7 CFR 1945.35 - Special EM loan training.  

Code of Federal Regulations, 2011 CFR

...2009-01-01 true Special EM loan training. 1945.35 Section 1945.35 Agriculture Regulations of the Department...CONTINUED) EMERGENCY Disaster Assistance-General § 1945.35 Special EM loan training. (a)...



EM-ONE : an architecture for reflective commonsense thinking  

E-print Network

This thesis describes EM-ONE, an architecture for commonsense thinking capable of reflective reasoning about situations involving physical, social, and mental dimensions. EM-ONE uses as its knowledge base a library of ...

Singh, Pushpinder, 1972-2006.




E-print Network


Lucero, Jorge Carlos



E-print Network


Maier, Rudolf Richard



E-print Network


Maier, Rudolf Richard


Marvin, robô construtor para competição em robótica móvel  

Microsoft Academic Search

renatohsp@gmail .com Resumo: Este artigo é sobre a construção do robô autônomo Marvin o Construtor, que foi construído para participar da IV Competição IEEE Brasileira de Robô. A tarefa consiste em empilhar blocos em uma área predeterminada em um menor tempo possível, ganha a torre mais alta. O robô, construído por alunos do Instituto Tecnológico de Aeronáutica (ITA), foi construído

André Martin Narciso; Carlos Augusto; Bentes da Silva; Jackson Paul Matsuura


On Convergence Properties of the EM Algorithm for Gaussian Mixtures  

Microsoft Academic Search

We build up the mathematical connection between the Expectation-Maximization (EM) algorithm and gradient-based approaches for maximum likelihood learning of finite gaussian mixtures. We show that the EM step in parameter space is obtained from the gradient via a projection matrix P, and we provide an explicit expression for the matrix. We then analyze the convergence of EM in terms of

Lei Xu; Michael I. Jordan




E-print Network

CURSO DE P�S-GRADUA��O EM METEOROLOGIA Coordenadora Acadêmica Maria Paulete Pereira Martins Membros Bueno Pereira, Ph.D., W.M.Rice University, 1980 Gilberto Fernando Fisch, Doutor, INPE, 1995 Iracema, INPE, 2002 Maria Paulete Pereira Martins, Doutora, INPE, 1996 Marley Cavalcante de Lima Moscati



E-print Network

CURSO DE P�S-GRADUA��O EM METEOROLOGIA Coordenadora Acadêmica Maria Paulete Pereira Martins Bueno Pereira, Ph.D., W.M.Rice University, 1980 Gilberto Fernando Fisch, Doutor, INPE, 1995 Iracema, INPE, 2002 Maria Paulete Pereira Martins, Doutora, INPE, 1996 Marley Cavalcante de Lima Moscati



E-print Network

CURSO DE P�S-GRADUA��O EM METEOROLOGIA Coordenadora Acadêmica Maria Paulete Pereira Martins-USP, 2002 �nio Bueno Pereira, Ph.D., W.M.Rice University, 1980 Gilberto Fernando Fisch, Doutor, INPE, 1995, INPE, 2002 Maria Paulete Pereira Martins, Doutora, INPE, 1996 Marley Cavalcante de Lima Moscati



E-print Network

GEOBULLETIN NOvEmBEr 8Th 2013 - 1 - GeoBulletin is distributed weekly, by E-mail. Contributions are requested! If you have a news item, a request, an announcement etc. email it to or leave it at the office, Room 225 by Noon on Wednesday. WEEKS LECTURE - FALL 2013 Nov. 8 Graham Kent

Carlson, Anders


EMS response to an airliner crash.  


This report of an aircraft crash at a major airport in Kingston, Jamaica examines the response of the local Emergency Medical Services (EMS). Factors that impacted the response are discussed, and the need for more disaster simulation exercises is highlighted. The objective of this case report was to document the response of EMS personnel to the crash of American Airlines Flight 331, and to utilize the information to examine and improve the present protocol. While multiple errors can occur during a mass-casualty event, these can be reduced by frequent simulation exercises during which various personnel practice and learn designated roles. Efficient triage, proper communication, and knowledge of the roles are important in ensuring the best possible outcome. While the triage system and response of the EMS personnel were effective for this magnitude of catastrophe, more work is needed in order to meet predetermined standards. Ways in which this can be overcome include: (1) hosting more disaster simulation exercises; (2) encouraging more involvement with first responders; and (3) strengthening the links in the local EMS system. Vigorous public education must be instituted and maintained. PMID:22853919

Dasgupta, Shuvra; French, Simone; Williams-Johnson, Jean; Hutson, Rhonda; Hart, Nicole; Wong, Mark; Williams, Eric; Espinosa, Kurdell; Maycock, Celeste; Edwards, Romayne; McCartney, Trevor; Cawich, Shamir; Crandon, Ivor



de Ps-Graduao em Enfermagem  

E-print Network

CAPES/PNPD A Profa. Dra Marta Lenise do Prado, docente do Programa de Pós-graduação em Enfermagem da (via e-mail), para agendar uma entrevista para arguição do currículo, considerando o perfil adequado ao

Floeter, Sergio Ricardo


CNMP, CSP, EMS and Writing It Down  

E-print Network

by farmers, leading to... · Increasing importance of "writing it down" #12;Examples.. · NMP, CNMP · PMPOp & plan for more · III - meet all natural resource concerns #12;NMP & CNMP · NMP in WI rules; CNMP and erosion #12;EMS is HQ · CSP, NMP, PMP, CNMP alphabet soup · Are components of an Environmental Management

Balser, Teri C.



E-print Network

to hydrothermal convection of groundwater connected to surface water Thermal springs are ubiquitous features whose;GEOBULLETIN NOvEmBEr 15Th 2013 - 2 - hydrothermal convection cells circulating groundwater within the near hydrothermal circulation of groundwater. For example, these requirements are met in many areas within

Carlson, Anders


Regional EM studies in the 80's  

NASA Astrophysics Data System (ADS)

The review describes in broad terms the development of regional EM studies during the last five-six years. Large simultaneous magnetometer arrays, broadband and dense profiling with five component instruments, the use of remote reference techniques and in-field data processing have increased both the number and the quality of EM surveys. The increase has been strong all over the world. An extensive list of references, divided geographically, is presented. Selected examples of regional resisitivity-versus-depth curves are shown for Africa, the Baikal region, the Baltic Shield, the Canadian Shield, the Carpathian regions, the Central Andes, Iceland, India, the Juan de Fuca Plate, the Münsterland Basin, the Rio Grande rift, the Scottish Caledonides, the Tasman Sea, and for the United States in general. Because of the influence of tectonic settings and the metamorphic grade of rocks, only qualitative aspects of the results are relevant. ‘Classical’ array studies, especially in Australia, in the Carpathian regions, in India, in North Germany and in Scotland have been reinterpreted and completed with more accurate 2D modelling and dense MT profiling. In the USA and Canada also new regions have been surveyed extensively. New regional EM work has been conducted extensively on the Baltic Shield and in Central and North Africa, Siberia, China, in the areas around the Caspian and Black Seas and in South America. The newest studies are supported by or compared with other geophysical data, which also are used in extrapolating for missing EM data density. There are several successful large-scale projects in operation: the European Geotraverse (EGT), the KAPG International Geotraverses and the EMSLAB project (with its first preliminary results). Regional EM studies have been increasingly applied to geothermal, hydrocarbon and mineral prospecting as well as local structural studies, e.g. studies of sites for nuclear waste disposal.

Hjelt, S. E.



Modelling and design for PM/EM magnetic bearings  

NASA Technical Reports Server (NTRS)

A mathematical model of a permanent magnet/electromagnet (PM/EM) radially active bearing is presented. The bearing is represented by both a reluctance model and a stiffness model. The reluctance model analyzes the magnetic circuit of the PM/EM bearings. By combining the two models, the performance of the bearing can be predicted given geometric dimensions, permanent magnet strength, and the parameters of the EM coils. The overall bearing design including the PM and EM design is subject to the performance requirement and physical constraints. A study of these requirements and constraints is discussed. The PM design is based on the required magnetic flux for proper geometric dimensions and magnet strength. The EM design is based on the stability and force slew rate consideration, and dictates the number of turns for the EM coils and the voltage and current of the power amplifier. An overall PM/EM bearing design methodology is proposed and a case study is also demonstrated.

Pang, D.; Kirk, J. A.; Anand, D. K.; Johnson, R. G.; Zmood, R. B.



The association between EMS workplace safety culture and safety outcomes  

PubMed Central

Objective Prior studies have highlighted wide variation in EMS workplace safety culture across agencies. We sought to determine the association between EMS workplace safety culture scores and patient or provider safety outcomes. Methods We administered a cross-sectional survey to EMS workers affiliated with a convenience sample of agencies. We recruited these agencies from a national EMS management organization. We used the EMS Safety Attitudes Questionnaire (EMS-SAQ) to measure workplace safety culture and the EMS Safety Inventory (EMS-SI), a tool developed to capture self-reported safety outcomes from EMS workers. The EMS-SAQ provides reliable and valid measures of six domains: safety climate, teamwork climate, perceptions of management, perceptions of working conditions, stress recognition, and job satisfaction. A panel of medical directors, paramedics, and occupational epidemiologists developed the EMS-SI to measure self-reported injury, medical errors and adverse events, and safety-compromising behaviors. We used hierarchical linear models to evaluate the association between EMS-SAQ scores and EMS-SI safety outcome measures. Results Sixteen percent of all respondents reported experiencing an injury in the past 3 months, four of every 10 respondents reported an error or adverse event (AE), and 90% reported safety-compromising behaviors. Respondents reporting injury scored lower on 5 of the 6 domains of safety culture. Respondents reporting an error or AE scored lower for 4 of the 6 domains, while respondents reporting safety-compromising behavior had lower safety culture scores for 5 of 6 domains. Conclusions Individual EMS worker perceptions of workplace safety culture are associated with composite measures of patient and provider safety outcomes. This study is preliminary evidence of the association between safety culture and patient or provider safety outcomes. PMID:21950463

Weaver, Matthew D.; Wang, Henry E.; Fairbanks, Rollin J.; Patterson, Daniel



Characterization of typo-, regio-, and stereo-selectivities of babaco latex lipase in aqueous and organic media.  


The unripe fruit of babaco (Vasconcellea x heilbornii; syn. Carica pentagona) contains a latex, similar to that in Carica papaya, which exhibits lipolytic activity. Herein, the regioselectivity, stereoselectivity and typoselectivity in both hydrolysis and acyltransfer reactions of babaco latex lipases were studied and compared to those of Carica papaya latex. In hydrolysis, both biocatalysts are 1,3-regioselective with ratios for 1,2-2,3-diacylglycerols/1,3-diacylglycerol of 6.5 and 21 for babaco and papaya, respectively. In contrast, papaya latex had a slight sn-3 stereopreference. Babaco latex displayed a higher activity on triacylglycerols with short chain and unsaturated fatty acids. PMID:18038267

Cambon, E; Rodriguez, J A; Pina, M; Arondel, V; Carriere, F; Turon, F; Ruales, J; Villeneuve, P



Facile, regio- and diastereoselective synthesis of spiro-pyrrolidine and pyrrolizine derivatives and evaluation of their antiproliferative activities.  


A number of novel spiro-pyrrolidines/pyrrolizines derivatives were synthesized through [3+2]-cycloaddition of azomethine ylides with 3,5-bis[(E)-arylmethylidene]tetrahydro-4(1H)-pyridinones 2a-n. Azomethine ylides were generated in situ from the reaction of 1H-indole-2,3-dione (isatin, 3) with N-methylglycine (sarcosine), phenylglycine, or proline. All compounds (50 ?M) were evaluated for their antiproliferative activity against human breast carcinoma (MDA-MB-231), leukemia lymphoblastic (CCRF-CEM), and ovarian carcinoma (SK-OV-3) cells. N-?-Phenyl substituted spiro-pyrrolidine derivatives (5a-n) showed higher antiproliferative activity in MDA-MB-231 than other cancer cell lines. Among spiro-pyrrolizines 6a-n, a number of derivatives including 6a-c and 6i-m showed a comparable activity with doxorubicin in all three cell lines. Among all compounds in three classes, 6a, 6b, and 6m, were found to be the most potent derivatives showing 64%, 87%, and 74% antiproliferative activity in MDA-MB-231, SK-OV-3, and CCRF-CEM cells, respectively. Compound 6b showed an IC50 value of 3.6 mM in CCRF-CEM cells. These data suggest the potential antiproliferative activity of spiro-pyrrolidines/pyrrolizines. PMID:25014532

Almansour, Abdulrahman I; Kumar, Raju Suresh; Beevi, Farzana; Shirazi, Amir Nasrolahi; Osman, Hasnah; Ismail, Rusli; Choon, Tan Soo; Sullivan, Brian; McCaffrey, Kellen; Nahhas, Alaa; Parang, Keykavous; Ali, Mohamed Ashraf



Mimics of the self-assembling chlorosomal bacteriochlorophylls: regio- and stereoselective synthesis and stereoanalysis of acyl(1-hydroxyalkyl)porphyrins.  


Diacylation of copper 10,20-bis(3,5-di-tert-butylphenylporphyrin) using Friedel-Crafts conditions at short reaction times, high concentrations of catalyst, and 0-4 degrees C affords only the 3,17-diacyl-substituted porphyrins, out of the 12 possible regioisomers. At longer reaction times and higher temperatures, the 3,13-diacyl compounds are also formed, and the two isomers can be conveniently separated by normal chromatographic techniques. Monoreduction of these diketones affords in good yields the corresponding acyl(1-hydroxyalkyl)porphyrins, which after zinc metalation are mimics of the natural chlorosomal bacteriochlorophyll (BChl) d. Racemate resolution by HPLC on a variety of chiral columns was achieved and further optimized, thus permitting easy access to enantiopure porphyrins. Enantioselective reductions proved to be less effective in this respect, giving moderate yields and only 79% ee in the best case. The absolute configuration of the 3(1)-stereocenter was assigned by independent chemical and spectroscopic methods. Self-assembly of a variety of these zinc BChl d mimics proves that a collinear arrangement of the hydroxyalkyl substituent with the zinc atom and the carbonyl substituent is not a stringent requirement, since both the 3,13 and the 3,17 regioisomers self-assemble readily as the racemates. Interestingly, the separated enantiomers self-assemble less readily, as judged by absorption, fluorescence, and transmission electron microscopy studies. Circular dichroism spectra of the self-assemblies show intense Cotton effects, which are mirror-images for the two 3(1)-enantiomers, proving that the supramolecular chirality is dependent on the configuration at the 3(1)-stereocenter. Upon disruption of these self-assemblies with methanol, which competes with zinc ligation, only very weak monomeric Cotton effects are present. The favored heterochiral self-assembly process may also be encountered for the natural BChls. This touches upon the long-standing problem of why both 3(1)-epimers are encountered in BChls in ratios that vary with the illumination and culturing conditions. PMID:19769331

Balaban, Teodor Silviu; Bhise, Anil Dnyanoba; Bringmann, Gerhard; Bürck, Jochen; Chappaz-Gillot, Cyril; Eichhöfer, Andreas; Fenske, Dieter; Götz, Daniel C G; Knauer, Michael; Mizoguchi, Tadashi; Mössinger, Dennis; Rösner, Harald; Roussel, Christian; Schraut, Michaela; Tamiaki, Hitoshi; Vanthuyne, Nicolas



Regio- and stereoselective synthesis of 2,3,5-trienoates by palladium-catalyzed alkoxycarbonylation of conjugated enyne carbonates.  


Palladium-catalyzed carbonylation of 2,4-enyne carbonates in an alcohol and under balloon pressure of CO proceeds through 1,5-substitution to yield (E)-2,3,5-trienoates. The olefin geometry of the substrate is important to control the overall stereochemistry of this alkoxycarbonylation method. The reaction proceeds through successive formation of ?-allylpalladium with an R(3) group oriented syn and ?-allenyl palladium complexes. PMID:25188027

Karagöz, Ezgi ?ule; Ku?, Melih; Akp?nar, Gürkan Eray; Artok, Levent



A New Procedure for Highly Regio? and Stereoselective Iodoacetoxylation of Protected Glycals and ??1,2?Cyclopropanated Sugars  

Microsoft Academic Search

Protected glycals and ??1,2?cyclopropanated sugars were converted in high yields and selectivities in less than 2 h at low temperatures to 2?deoxy?2?iodoglycosyl acetates or novel 2?deoxy?2?iodomethylglycosyl acetates using the simple, inexpensive reagent mixture of ammonium iodide, hydrogen peroxide, and acetic anhydride\\/acetic acid in acetonitrile. The protected glycals gave rise to 2?deoxy?2?bromoglycosyl acetates when ammonium bromide was used instead of the iodide,

David W. Gammon; Henok H. Kinfe; Dirk E. De Vos; Pierre A. Jacobs; Bert F. Sels



Regio-and Stereochemistry of Alkene Expulsion from Ionized sec-Alkyl Phenyl Ethers John C. Traeger  

E-print Network

among trans-2-butene, cis-2-butene, and 1-butene in a ratio of approximately 6:5:4, exhibiting-half at 11.92 eV. Ion-neutral complexes from sBuOPh yield nearly equal proportions of 1-butene and 2-butenes

Morton, Thomas Hellman


Regio- and stereoselective biomimetic synthesis of oligostilbenoid dimers from resveratrol analogues: influence of the solvent, oxidant, and substitution.  


Oligostilbenoids are polyphenols that are widely distributed in nature with multifaceted biological activities. To achieve biomimetic synthesis of unnatural derivatives, we subjected three resveratrol analogues to oligomerization by means of one-electron oxidants. Upon varying the metal oxidant (AgOAc, CuBr(2), FeCl(3)6 H(2)O, FeCl(3)6 H(2)O/NaI, PbO(2), VOF(3)), the solvent (over the whole range of polarities), and the oxygenated substitution pattern of the starting material, stilbenoid oligomers with totally different carbon skeletons were obtained. Here we propose to explain the determinism of the type of skeleton produced with the aid of hard and soft acid/base concepts in conjunction with the solvating properties of the solvents and the preferred alignment by the effect of pi stacking. PMID:19003831

Velu, Saraswati S; Buniyamin, Irmaizatussyehdany; Ching, Lee Kiew; Feroz, Fareeda; Noorbatcha, Ibrahim; Gee, Lim Chuan; Awang, Khalijah; Wahab, Ibtisam Abd; Weber, Jean-Frédéric Faizal



Stereo- and regio-selective one-pot synthesis of triazole-based unnatural amino acids and ß- amino triazoles  

EPA Science Inventory

Synthesis of triazole based unnatural amino acids and ß-amino triazole has been described via stereo and regioselective one-pot multi-component reaction of sulfamidates, sodium azide, and alkynes under MW conditions. The developed method is applicable to a broad substrate scope a...


Crosshole EM in steel-cased boreholes  

SciTech Connect

The application of crosshole EM methods through steel well-casing was investigated in theoretical, laboratory and field studies. A numerical code was developed that calculates the attenuation and phase delay of an EM dipole signal propagated through a steel well casing lodged in a homogeneous medium. The code was validated with a scale model and used for sensitivity studies of casing and formation properties. Finally, field measurements were made in an oil field undergoing waterflooding. Our most important findings are that (1) crosshole surveys are feasible using a well pair with one metallic and one non-metallic casing. (2) The casing effect seems be localized within the pipe section that includes the sensor. (3) The effects of the casing can be corrected using simple means and (4) crosshole field data that are sensitive to both formation and casing were acquired in a working environment.

Wilt, M.; Lee, K.H.; Becker, A.; Spies, B.; Wang, B.



Helicopter EMS: Research Endpoints and Potential Benefits  

PubMed Central

Patients, EMS systems, and healthcare regions benefit from Helicopter EMS (HEMS) utilization. This article discusses these benefits in terms of specific endpoints utilized in research projects. The endpoint of interest, be it primary, secondary, or surrogate, is important to understand in the deployment of HEMS resources or in planning further HEMS outcomes research. The most important outcomes are those which show potential benefits to the patients, such as functional survival, pain relief, and earlier ALS care. Case reports are also important “outcomes” publications. The benefits of HEMS in the rural setting is the ability to provide timely access to Level I or Level II trauma centers and in nontrauma, interfacility transport of cardiac, stroke, and even sepsis patients. Many HEMS crews have pharmacologic and procedural capabilities that bring a different level of care to a trauma scene or small referring hospital, especially in the rural setting. Regional healthcare and EMS system's benefit from HEMS by their capability to extend the advanced level of care throughout a region, provide a “backup” for areas with limited ALS coverage, minimize transport times, make available direct transport to specialized centers, and offer flexibility of transport in overloaded hospital systems. PMID:22203905

Thomas, Stephen H.; Arthur, Annette O.



Sequence analysis of two tandemly linked Em genes from wheat  

Microsoft Academic Search

DNA sequences are presented for two members of the wheat Em gene family. The sequences correspond to the two linked genes at the Xem-1AL locus. Comparisons of these sequences with that of another wheat Em gene and two Em cDNA clones reveals substantial homology within the protein-coding regions, and the presence in the 5'-flanking regions of the genomic sequences of

T. Simon Futers; Sertac Onde; Muge Turet; Andrew C. Cuming




E-print Network


Maier, Rudolf Richard



E-print Network


Maier, Rudolf Richard



E-print Network


Maier, Rudolf Richard



E-print Network


Lucero, Jorge Carlos



E-print Network


Maier, Rudolf Richard



E-print Network


Lucero, Jorge Carlos


Photon kinetic description of 1D relativistic EM pulse solitons  

Microsoft Academic Search

Photon kinetics provides a novel formalism to describe intense EM fields-plasma interactions, where the EM fields are described as a collection of quasi-particles (photons). Photon kinetics provides a better physical picture of the EM fields dynamics, is computionally less demanding, and allows for an easy description of broadband incoherent light pulses. We have developed a 1D photon kinetic code, where

R. Trines; R. Bingham; W. B. Mori; L. O. Silva



Propriedades termodinâmicas de um gás ideal em superfícies hiperbólicas compactas.  

E-print Network

??Neste trabalho investigamos algumas propriedades termodinâmicas de gases ideais em superfícies compactas de curvatura constante e negativa. Super- fícies com propriedades similares aparecem, por exemplo,… (more)

Diego de Flôor e Silva




Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. HI PAR (ACQUISITION RADAR) TOWER AND ENLISTED MEN (EM) BARRACKS WITH RADAR ATTACHED. - Nike Hercules Missile Battery Summit Site, Battery Control Administration & Barracks Building, Anchorage, Anchorage, AK



E-print Network

BUSCA LOCAL PARA P´OS-PROCESSAMENTO EM RESULTADOS DE OTIMIZA¸C~AO MULTI-OBJETIVO EM REDES DE FILAS otimiza¸c~ao de redes de filas finitas, a capacidade total do sistema em ´areas de espera deve ser a menor redistribui¸c~ao de ´areas de circula¸c~ao entre as filas, preservando fixa a capacidade total do sistema. Um

Cruz, Frederico



Microsoft Academic Search

This article refers to a possible critic of the Brazilian military and dictatorial regime in the 1960´s and 1970s, trough the eyes of João Paz, a character in the novel of Erico Veríssimo, Incidente em Antares . The research, from a bibliographic point of view, has been based on recent theories that relate to facts in the History and Literature

Daniela Freitas Torres; Elaine dos Santos



Microsoft Academic Search

Introdução Nos últimos anos, a história da ciência vem sendo introduzida em materiais didáticos utilizados em sala de aula. Uma das razões para isso é a pressão de órgãos governamentais, tais como a Secretaria de Educação Básica, responsável pela avaliação destes livros dentro do Programa Nacional de Livros Didáticos para o ens ino fundamental e médio. Os editais destes programas

Cibelle Celestino Silva; Ana Carolina Pimentel


Processamento auditivo e SPECT em crianças com dislexia  

Microsoft Academic Search

RESUMO - Aplicamos em um grupo de 36 crianças os testes dicótico de dígitos, dicótico de dissílabos altern a- dos e dicótico não-verbal, os quais fazem parte do conjunto de avaliação do processamento auditivo. As crianças foram divididas em dois grupos que foram correlacionados: grupo experimental (GE) formado por 18 crianças com diagnóstico de dislexia e 18 crianças normais compondo

Luciane Sauer; Liliane Desgualdo Pereira; Sylvia Maria Ciasca; Magda Pestun; Marilisa M. Guerreiro



10 CFR Appendixes E-M to Part 52 - [Reserved  

10 Energy 2 2014-01-01 2014-01-01 false [Reserved] E Appendixes E-M to Part 52 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Appendixes E-M to Part 52...



Standard Errors for EM Estimates in Generalized Linear Models with  

E-print Network

. As additional covariate among others the temperature was recorded. The bacteria content was determinedStandard Errors for EM Estimates in Generalized Linear Models with Random Effects Herwig Friedl of EM estimates in generalized linear models with random effects. Quadrature formulae are used

Friedl, Herwig


Stochastic EM-based TFBS motif discovery with MITSU  

PubMed Central

Motivation: The Expectation–Maximization (EM) algorithm has been successfully applied to the problem of transcription factor binding site (TFBS) motif discovery and underlies the most widely used motif discovery algorithms. In the wider field of probabilistic modelling, the stochastic EM (sEM) algorithm has been used to overcome some of the limitations of the EM algorithm; however, the application of sEM to motif discovery has not been fully explored. Results: We present MITSU (Motif discovery by ITerative Sampling and Updating), a novel algorithm for motif discovery, which combines sEM with an improved approximation to the likelihood function, which is unconstrained with regard to the distribution of motif occurrences within the input dataset. The algorithm is evaluated quantitatively on realistic synthetic data and several collections of characterized prokaryotic TFBS motifs and shown to outperform EM and an alternative sEM-based algorithm, particularly in terms of site-level positive predictive value. Availability and implementation: Java executable available for download at, supported on Linux/OS X. Contact: PMID:24931999

Kilpatrick, Alastair M.; Ward, Bruce; Aitken, Stuart



Under Review Scaling Down EM Using Graph Based  

E-print Network

a probabilistic model formulation characterized by the parameters of the probability distribution. For example, in the above applications [3, 17] a #12;Scaling Down EM Using Graph Based Models 3 Gaussian distributionUnder Review Scaling Down EM Using Graph Based Models Ian Davidson Department of Computer Science

Davidson, Ian


A Double Layer Electromagnetic Cloak And GL EM Modeling  

E-print Network

In this paper, we propose a novel electromagnetic (EM) cloaking structure that consists of two annular layers between three spherical shells and model its performance numerically and theoretically by using a Global and Local EM field (GL) method. The two annular layers contain distinct cloaking materials: the outer layer provides invisibility; the inner layer is fully absorbing. The cloaking materials are weakly degenerative. The wavefield from an EM source located outside the cloak propagates as in free space outside the outer shell, never be disturbed by the cloak and does not penetrate into the inner absorbing layer and concealment. The field of a source located inside inner layer or the cloaked concealment is completely absorbed by the inner layer and never reaches the outside of the middle shell, Moreover, the EM wavefield excited in concealment is not disrupted by the cloak. There exists no Maxwell EM wavefield can be excited in a single layer cloaked concealment which is filled by normal material. More...

Xie, Ganquan; Xie, Feng; Xie, Lee



Electromagnetic optimization of EMS-MAGLEV systems  

SciTech Connect

In EMS-MAGLEV high-speed transport systems, devices for propulsion, levitation and contactless on-board electric power transfer are combined in a single electromagnetic structure. The strong coupling among the windings affects the performance of each device and requires the utilization of numerical codes. The paper describes an overall optimization procedure, based on a suitable mathematical model of the system, which takes into account several items of the system performance. The parameters of the model are calculated by an automated sequence of FEM analyses of the configuration. Both the linear generator output characteristics and the propulsion force ripple are improved applying the procedure to a reference configuration. The results are compared with the results obtained by a sequence of partial optimizations operating separately on two different subsets of the geometric parameters.

Andriollo, M.; Martinelli, G.; Morini, A.; Tortella, A. [Univ. of Padova (Italy). Dept. of Electrical Engineering] [Univ. of Padova (Italy). Dept. of Electrical Engineering



DOE EM industry programs robotics development  

SciTech Connect

The Office of Science and Technology (OST) manages an aggressive program for RD&D, as well as testing and evaluation for the U.S. Department of Energy`s (DOE) Environmental Management (EM) organization. The goal is to develop new and improved environmental restoration and waste management technologies to clean up the inventory of the DOE weapons complex faster, safer, and cheaper than is possible with currently available technologies. OST has organized technology management activities along focus teams for each major problem area. There are currently five focus areas: decontamination and decommissioning, tanks, subsurface contaminants, mixed waste, and plutonium. In addition, OST is pursuing research and development (R&D) that cuts across these focus areas by having applications in two or more focus areas. Currently, there are three cross-cutting programs: the robotics technology development; characterization, monitoring, and sensor technologies; and efficient separations and processing.

Staubly, R.; Kothari, V. [Dept. of Energy, Morgantown, WV (United States)



Evaluation of Fracture Azimuth by EM Wave and Elastic Wave  

NASA Astrophysics Data System (ADS)

Fracture system plays an important role in the development of underground energy, for example enhanced geothermal system (EGS), oil shale and shale gas, etc. Therefore, it becomes more and more important to detect and evaluate the fracture system. Geophysical prospecting is an useful method to evaluate the characteristics of the subsurface fractures. Currently, micro-seismology, multi-wave seismic exploration, and electromagnetic (EM) survey are reported to be used for the purpose. We are studying a method using both elastic wave and EM wave to detect and evaluate the fracture azimuth in laboratory. First, we build a 3D horizontal transverse isotropy (HTI) model, shown in the figure 1, by dry parallel fractures system, which was constructed by plexiglass plates and papers. Then, we used the ultrasonic system to obtain reflected S-wave data. Depending on the shear wave splitting, we evaluated the fracture azimuth by the algorithm of Pearson correlation coefficient. In addition, we used the full Polarimetric ultra wide band electromagnetic (FP-UWB-EM) wave System, shown in the figure 2, to obtain full polarimetric reflected EM-wave data. Depending on the rotation of the EM wave polarimetry, we evaluated the fracture azimuth by the the ration between maximum amplitude of co-polarimetric EM wave and maximum amplitude of cross-polarimetric EM wave. Finally, we used both EM-wave data and S-wave data to evaluate the fracture azimuth by the method of cross plot and statistical mathematics. To sum up, we found that FP-UWB-EM wave can be used to evaluated the fracture azimuth and is more accurate than ultrasound wave. Also joint evaluation using both data could improve the precision.

Feng, X.; Wang, Q.; Liu, C.; Lu, Q.; Zeng, Z.; Liang, W.; Yu, Y.; Ren, Q.



Cultivo hidropônico de lisianto p ara flor de corte em sistema de fluxo laminar de nutrientes  

Microsoft Academic Search

Resumo - O objetivo deste trabalho foi avaliar as características produtivas e comerciais do cultivo de quatro cultivares de lisianto (Eustoma grandiflorum) em três soluções nutritivas em sistema de fluxo laminar de nutrientes (NFT). Utilizou-se o delineamento em blocos casualizados, em esquema fatorial 4x3, com três repetições. Os tratamentos foram compostos de quatro cultivares (Echo Champagne, Mariachi Pure White, Balboa

Alice Antonello; Londero Backes; José Geraldo Barbosa; Paulo Roberto Cecon; José Antonio Saraiva Grossi; Rogério Luiz Backes; Fernando Luiz Finger; Av. P. H. Rolfs


Autonomia e Motivação em narrativas de aprendizes de português como língua estrangeira1  

Microsoft Academic Search

Neste artigo, discuto os resultados de minha pesquisa dentro do projeto AMFALE - Autonomia em um Modelo Fractal de Aquisição de Língua Estrangeira. Com base em conceitos de autonomia e motivação e na correlação entre eles, analiso narrativas de aprendizes de português como língua estrangeira em Belo Horizonte. Tais análises atestam que a experiência de aprendizagem inserida em uma comunidade

Fernanda Sousa Carvalho


An Innovative Tool to Assist in Rural EMS Response  

E-print Network

technologies for EMS -NextGeneration 911 -IP telephony -AACN -Mobile phones -Computer Aided Dispatch (CAD) -GPS (security & privacy) !Users must want to use it, be able to use it, like to use it !Leverage growth

Minnesota, University of


EM 9043 October 2011 Growing Farms: Successful Whole  

E-print Network

of the Oregon State University Extension Service Small Farms Program ( #12 ................................................................5 SWOT Analysis...............................................................7 Resource InventoryEM 9043 · October 2011 Growing Farms: Successful Whole Farm Management Planning Book Think It

Tullos, Desiree


Genética de populações e relações de parentesco em Ciconiiformes (Aves).  

E-print Network

??Estudos de genética de populações e de parentesco genético foram desenvolvidos em colhereiro (Platalea ajaja), cabeça-seca (Mycteria americana) e garça-branca-grande (Ardea alba egretta), de colônias… (more)

Carolina Isabel Miño



Structure of Matter, Forces, EM Waves, Spectroscopy, Doppler Effect  

NSDL National Science Digital Library

These supplemental class notes cover the basic properties of matter, the nature of forces, the electromagnetic spectrum, and how astronomers exploit the properties of the EM spectrum to deduce the physical nature of distant objects.

O'Connell, Robert



NASA EM Followup of LIGO-Virgo Candidate Events  

NASA Technical Reports Server (NTRS)

We present a strategy for a follow-up of LIGO-Virgo candidate events using offline survey data from several NASA high-energy photon instruments aboard RXTE, Swift, and Fermi. Time and sky-location information provided by the GW trigger allows for a targeted search for prompt and afterglow EM signals. In doing so, we expect to be sensitive to signals which are too weak to be publicly reported as astrophysical EM events.

Blackburn, Lindy L.



Users of midwest EMS firm stuck without software  

SciTech Connect

Four midwest energy management system (EMS) users report delays in software delivery and a failure to achieve energy savings with National Control Systems Inc. (NCS) equipment. A fifth user has already replaced an unsatisfactory NCS system. Representatives of the users relate their experiences in trying to make the EMS systems works and to acquire the necessary software beyond the original start/stop functions. Most expect to deal with larger, more established companies in the future. (DCK)

Galvin, C.



EM algorithm estimation of TCM scheme over multipath fading  

E-print Network

estimate is available to the receiver. B. Previous Research The following are some studies in application of EM algorithm in a, communicat, ion problem. Han and Georghiades [I] investigated the application of EM algorithm to t, he optimum receiver... 4. In Sections A and C, the structure of encoder an&i decoder implemented in the simulation is described. We described how the fading model is simulated in Section B. A. Transmitter A transmitter used in this study employs Ungerboeck's 8-state...

Gunawan, Wiedy



An Effective EMS Hardware and Software Interface- The Trained Operator  

E-print Network

you have es tablished operator training objectives, selecting appropriate training methods becomes easier. OPERATOR SKILL CATEGORIES Identifying and defining your EMS instructional objectives can be a fairly straightforward process. There is a... ings are minimal. An operator needs the full capability of being able to address all the EMS features and related individ ual building functions. Can you see the results of having a fully trained operator? Less personal frustration, improved use...

Cherry, C. L.


EM clustering analysis of diabetes patients basic diagnosis index.  


Cluster analysis can group similar instances into same group and different instances into different groups. It assigns classes to samples without known the classes in advance. EM clustering algorithm can find number of distributions of generating data and build "mixture models". It identifies groups that are either overlapping or varying sizes and shapes. In this project, by using EM in Weka system, diabetes patient basic diagnosis index data have been analyzed for clustering. PMID:16779444

Wu, Cai; Steinbauer, Jeffrey R; Kuo, Grace M



EM Task 9 - Centrifugal Membrane Filtration  

SciTech Connect

This project is designed to establish the utility of a novel centrifugal membrane filtration technology for the remediation of liquid mixed waste streams at US Department of Energy (DOE) facilities in support of the DOE Environmental Management (EM) program. The Energy and Environmental Research Center (EERC) has teamed with SpinTek Membrane Systems, Inc., a small business and owner of the novel centrifugal membrane filtration technology, to establish the applicability of the technology to DOE site remediation and the commercial viability of the technology for liquid mixed waste stream remediation. The technology is a uniquely configured process that makes use of ultrafiltration and centrifugal force to separate suspended and dissolved solids from liquid waste streams, producing a filtered water stream and a low-volume contaminated concentrate stream. This technology has the potential for effective and efficient waste volume minimization, the treatment of liquid tank wastes, the remediation of contaminated groundwater plumes, and the treatment of secondary liquid waste streams from other remediation processes, as well as the liquid waste stream generated during decontamination and decommissioning activities.

Stevens, B.G.; Stepan, D.J.; Hetland, M.D.



DOE EM industry programs robotics development  

SciTech Connect

The Office of Science and Technology (OST) manages an aggressive program for RD and D, as well as testing and evaluation for the Department of Energy`s (DOE`s) Environmental Management (EM) organization. The goal is to develop new and improved environmental restoration and waste management technologies to clean up the inventory of the DOE weapons complex faster, safer, and cheaper than is possible with currently available technologies. Robotic systems reduce worker exposure to the absolute minimum, while providing proven, cost-effective, and, for some applications, the only acceptable technique for addressing challenging problems. Development of robotic systems for remote operations occurs in three main categories: tank waste characterization and retrieval; decontamination and dismantlement; and characterization, mapping, and inspection systems. In addition, the Federal Energy Technology Center (FETC) has some other projects which fall under the heading of supporting R and D. The central objective of all FETC robotic projects is to make robotic systems more attractive by reducing costs and health risks associated with the deployment of robotic technologies in the cleanup of the nuclear weapons complex. This will be accomplished through development of robots that are cheaper, faster, safer, and more reliable, as well as more straightforward to modify/adapt and more intuitive to operate with autonomous capabilities and intelligent controls that prevent accidents and optimize task execution.

Staubly, R.; Kothari, V.



Isolamento de Salmonella spp. em pombos (Columba livia) no Distrito Federal : aspecto de relevância ao sistema de vigilância em saúde.  

E-print Network

??Dissertação (mestrado)—Universidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, Programa de Pós-Graduação em Saúde Animal, 2014. A domesticação de pombos da espécie Columba livia,… (more)

Santos, Ivanildo de Oliveira Correia



Condensação de Bose-Einstein para um gás de bósons não interagentes em confinamentos bidimensionais em automatos celulares complexos.  

E-print Network

??Neste trabalho estudamos as propriedades termodinâmicas da Condensação de Bose-Einstein (CBE) para um gás de bósons não-interagentes confinado em potenciais bidimensionais V(x,y) que apresentam classicamente,… (more)

Daniel Schardosim Calovi



STF mantm cobrana de taxa para inscrio em vestibular A Procuradoria-Geral Federal em atuao conjunta com a Procuradoria Regional  

E-print Network

STF mantém cobrança de taxa para inscrição em vestibular A Procuradoria-Geral Federal em atuação sustentava a constitucionalidade da cobrança da taxa de vestibular. Ao apreciar o caso, a Ministra Ellen a de inscrição em vestibular. Fonte: STF #12;

Floeter, Sergio Ricardo


Astronomia para/com crianças carentes em Limeira  

NASA Astrophysics Data System (ADS)

Em 2001, o Instituto Superior de Ciências Aplicadas (ISCA Faculdades de Limeira) iniciou um projeto pelo qual o Observatório do Morro Azul empreendeu uma parceria com o Centro de Promoção Social Municipal (CEPROSOM), instituição mantida pela Prefeitura Municipal de Limeira para atender crianças e adolescentes carentes. O CEPROSOM contava com dois projetos: Projeto Centro de Convivência Infantil (CCI) e Programa Criança e Adolescente (PCA), que atendiam crianças e adolescentes em Centros Comunitários de diversas áreas da cidade. Esses projetos têm como prioridades estabelecer atividades prazerosas para as crianças no sentido de retirá-las das ruas. Assim sendo, as crianças passaram a ter mais um tipo de atividade - as visitas ao observatório. Este painel descreve as várias fases do projeto, que envolveu: reuniões de planejamento, curso de Astronomia para as orientadoras dos CCIs e PCAs, atividades relacionadas a visitas das crianças ao Observatório, proposta de construção de gnômons e relógios de Sol nos diversos Centros Comunitários de Limeira e divulgação do projeto na imprensa. O painel inclui discussões sobre a aprendizagem de crianças carentes, relatos que mostram a postura das orientadoras sobre a pertinência do ensino de Astronomia, relatos do monitor que fez o atendimento no Observatório e o que o número de crianças atendidas representou para as atividades da instituição desde o início de suas atividades e, em particular, em 2001. Os resultados são baseados na análise de relatos das orientadoras e do monitor do Observatório, registros de visitas e matérias da imprensa local. Conclui com uma avaliação do que tal projeto representou para as Instituições participantes. Para o Observatório, em particular, foi feita uma análise com relação às outras modalidades de atendimentos que envolvem alunos de escolas e público em geral. Também é abordada a questão do compromisso social do Observatório na educação do público em questão.

Bretones, P. S.; Oliveira, V. C.



Quantitation of PET data with the EM reconstruction technique  

SciTech Connect

The expectation maximization (EM) algorithm offers high spatial resolution and excellent noise reduction with low statistics PET data, since it incorporates the Poisson nature of the data. The main difficulties are long computation times, difficulties to find appropriate criteria to terminate the reconstruction and to quantify the resulting image data. In the present work a modified EM algorithm has been implements on a VAX 11/780. Its capability to quantify image data has been tested in phantom studies and in two clinical cases, cerebral blood flow studies and dopamine D2-receptor studies. Data from phantom studies indicate the superiority of images reconstructed with the EM technique compared to images reconstructed with the conventional filtered back-projection (FB) technique in areas with low statistics. At higher statistics the noise characteristics of the two techniques coincide. Clinical data support these findings.

Rosenqvist, G.; Dahlbom, M.; Erikson, L.; Bohm, C.; Blomqvist, G.



Longitudinal information and radiation damage in EM calorimetry  

SciTech Connect

The SCC radiation field is higher than that encountered by previous hadron collider detectors. In particular, the electromagnetic (EM) calorimeter compartment sees the highest radiation dose. Since an EM calorimeter also makes the most precise energy measurement, special care must be lavished on this part of a calorimeter. Previous studies have concentrated on Monte Carlo examinations of 2 longitudinal compartments within the EM which can alleviate radiation damage. Recently, it was realized that a ``shower maximum`` detector, such as exists in CDF, also contains information of the conversion point of an electromagnetic shower. As such, it can potentially be used in a fashion analogous to the longitudinal compartments, although it is not designed to be optimized for this role.

Green, D.



Longitudinal information and radiation damage in EM calorimetry  

SciTech Connect

The SCC radiation field is higher than that encountered by previous hadron collider detectors. In particular, the electromagnetic (EM) calorimeter compartment sees the highest radiation dose. Since an EM calorimeter also makes the most precise energy measurement, special care must be lavished on this part of a calorimeter. Previous studies have concentrated on Monte Carlo examinations of 2 longitudinal compartments within the EM which can alleviate radiation damage. Recently, it was realized that a shower maximum'' detector, such as exists in CDF, also contains information of the conversion point of an electromagnetic shower. As such, it can potentially be used in a fashion analogous to the longitudinal compartments, although it is not designed to be optimized for this role.

Green, D.



Propulsion From a Rotating EM Tether at Jupiter  

NASA Technical Reports Server (NTRS)

The Jovian system with its rapid planetary rotation and strong magnetic field presents exciting opportunities for the use of electrodynamic (EM) tethers. Previous analysis for a radial, 10 km length tether demonstrated the possibility of propulsive forces as large as 50 Newtons near the planet. For orbital positions beyond about 2.5 Jovian radii, an EM tether can simultaneously be used for power and increases in the orbital altitude. Although the previous study demonstrated the physical feasibility of EM tether use at Jupiter, it did not address the issues of limited gravity gradient force for tether orientation and the practical use of this technology in an engineered system. This presentation will discuss these issues and current progress in an ongoing science/engineering transitional study.

Gallagher, D. L.; Moore, J.



EMS Stretcher "Misadventures" in a Large, Urban EMS System: A Descriptive Analysis of Contributing Factors and Resultant Injuries  

PubMed Central

Purpose. There is a paucity of data regarding EMS stretcher-operation-related injuries. This study describes and analyzes characteristics associated with undesirable stretcher operations, with or without resultant injury in a large, urban EMS agency. Methods. In the study agency, all stretcher-related “misadventures” are required to be documented, regardless of whether injury results. All stretcher-related reports between July 1, 2009 and June 30, 2010 were queried in retrospective analysis, avoiding Hawthorne effect in stretcher operations. Results. During the year studied, 129,110 patients were transported. 23 stretcher incidents were reported (0.16 per 1,000 transports). No patient injury occurred. Four EMS providers sustained minor injuries. Among contributing aspects, the most common involved operations surrounding the stretcher-ambulance safety latch, 14/23 (60.9%). From a personnel injury prevention perspective, there exists a significant relationship between combative patients and crew injury related to stretcher operation, Fisher's exact test 0.048. Conclusions. In this large, urban EMS system, the incidence of injury related to stretcher operations in the one-year study period is markedly low, with few personnel injuries and no patient injuries incurred. Safety for EMS personnel and patients could be advanced by educational initiatives that highlight specific events and conditions contributing to stretcher-related adverse events. PMID:22606379

Goodloe, Jeffrey M.; Crowder, Christopher J.; Arthur, Annette O.; Thomas, Stephen H.



Mixture densities, maximum likelihood, and the EM algorithm  

NASA Technical Reports Server (NTRS)

The problem of estimating the parameters which determine a mixture density is reviewed as well as maximum likelihood estimation for it. A particular iterative procedure for numerically approximating maximum likelihood estimates for mixture density problems is considered. This EM algorithm, is a specialization to the mixture density context of a general algorithm of the same name used to approximate maximum likelihood estimates for incomplete data problems. The formulation and theoretical and practical properties of the EM algorithm for mixture densities are discussed focussing in particular on mixtures of densities from exponential families.

Redner, R. A.; Walker, H. F.



Developments in the EM-CCD camera for OGRE  

NASA Astrophysics Data System (ADS)

The Off-plane Grating Rocket Experiment (OGRE) is a sub-orbital rocket payload designed to advance the development of several emerging technologies for use on space missions. The payload consists of a high resolution soft X-ray spectrometer based around an optic made from precision cut and ground, single crystal silicon mirrors, a module of off-plane gratings and a camera array based around Electron Multiplying CCD (EM-CCD) technology. This paper gives an overview of OGRE with emphasis on the detector array; specifically this paper will address the reasons that EM-CCDs are the detector of choice and the advantages and disadvantages that this technology offers.

Tutt, James H.; McEntaffer, Randall L.; DeRoo, Casey; Schultz, Ted; Miles, Drew M.; Zhang, William; Murray, Neil J.; Holland, Andrew D.; Cash, Webster; Rogers, Thomas; O'Dell, Steve; Gaskin, Jessica; Kolodziejczak, Jeff; Evagora, Anthony M.; Holland, Karen; Colebrook, David



Waste fuel, EMS may save plant $1M yearly  

SciTech Connect

A mixture of paper trash and coal ash fueling an Erie, Pa. General Electric plant and a Network 90 microprocessor-based energy-management system (EMS) to optimize boiler efficiency will cost about $3 million and have a three-to-four-year payback. Over half the savings will come from the avoided costs of burning plant-generated trash. The EMS system will monitor fuel requirements in the boiler and compensate for changes in steam demand. It will also monitor plant electrical needs and control the steam diverted for cogeneration. (DCK)

Barber, J.



Aquisi??o de Estreptococos Mutans e Desenvolvimento de C?rie Dental em Primog?nitos  

PubMed Central

Objetivo Avaliar o momento de aquisição de estreptococos mutans (EM), desenvolvimento de cárie dental e as variáveis a eles associadas no decorrer de 23 meses, em primogênitos de famílias de baixo nível socioeconômico, desde os sete meses de idade. Método A amostra foi selecionada com base em mães densamente colonizadas por EM, incluindo todos os membros de 14 famílias que conviviam na mesma casa. Foram envolvidos no estudo 14 mães, pais e primogênitos e 8 parentes, na maioria avós. Exames clínicos e radiográficos iniciais determinaram os índices de cárie e condição periodontal dos adultos. Contagens de EM foram feitas em todos os adultos nas duas primeiras visitas. Nas crianças foram avaliados os níveis de EM, o número de dentes e de cáries, em quatro visitas. Resultados A prevalência de EM nos adultos foi alta, estando ausente em apenas um dos pais. EM foram detectados em 1, 2, 3 e 10 crianças, respectivamente nas visitas #1, 2, 3 e 4. A cárie dental foi detectada em apenas três crianças na última visita (aos 30 meses de idade), as quais apresentaram escores de EM significantemente maiores que as crianças sem cárie, na mesma visita. Conclusão Exclusivamente a condição social de baixa renda e mães densamente colonizadas por EM não são sinônimo de colonização precoce e alta atividade de cárie em crianças cuidadas em casa. O desenvolvimento de cárie está significantemente associado a escores elevados de EM nas crianças. PMID:22022218

NOCE, Erica; RUBIRA, Cassia Maria Fischer; da Silva ROSA, Odila Pereira; da SILVA, Salete Moura Bonifacio; BRETZ, Walter Antonio




E-print Network

de livro com ISBN ou paper em periódico Qualis B2 ou inferior, 15 pontos por livro ou paper em (Máximo 100 pontos) 100 (*) 7 pontos por capítulo de livro com ISBN ou paper em periódico Qualis B2 ou inferior, 15 pontos por livro ou paper em periódico Qualis B1 ou superior. (**) 2,5 por ano/projeto (***) 2

Maier, Rudolf Richard


Airborne EM for geothermal and hydrogeological mapping  

NASA Astrophysics Data System (ADS)

Within the "VIGOR" project, aimed at assessing the geothermal potential of four regions in southern Italy, Airborne EM data have been acquired, modeled and interpreted. The system deployed was SkyTEM, a time-domain helicopter electromagnetic system designed for hydrogeophysical, environmental and mineral investigations. The AEM data provide, after data acquisition, analysis, processing, and modeling, a distribution volume of electrical resistivity, spanning an investigation depth from ground surface of few hundred meters, depending on resistivity condition. Resistivity is an important physical parameter for geothermal investigation, since it proved to be very effective in mapping anomalies due to hydrothermal fluid circulation, which usually has high salt content and produces clayey alteration minerals. Since the project required, among other issues, to define geothermal resources at shallow level, it was decided to perform a test with an airborne electromagnetic geophysical survey, to verify the advantages offered by the system in covering large areas in a short time. The geophysical survey was carried out in Sicily, Italy, in late 2011, over two test sites named "Termini" and "Western Sicily". The two areas were chosen on different basis. "Termini" area is covered by extensive geological surveys, and was going to be investigated also by means of electrical tomography in its northern part. Since geological condition of Sicily, even at shallow depth, is very complex, this area provided a good place for defining the resistivity values of the main geological units outcropping in the region. "Termini" survey has been also an occasion to define relations between resistivity distribution, lithological units and thermal conductivity. The "Western Sicily" area cover the main thermal manifestations of western Sicily, and the research target was to establish whether they are characterized by common hydrogeological or tectonic features that could be mapped by resistivity. SkyTEM data have been acquired in a series of flight lines and were then processed and inverted. In the "Termini" area the flight line spacing had 150 m separation. In the "Western Sicily" area two different line spacing were used: the 1 km spacing was used for the regional mapping, whereas for infill areas, around the main hydrothermal springs, the flight lines had 100 m spacing. The total number of flight line was 4580 km, and the explored surface was in excess of 2000 km2. After acquisition, data were processed to eliminate coupling with infrastructures, and noise. Inversions was then carried out using the quasi 3-D Spatially Constrained Inversion. The obtained resistivity volume has then been the base for a detailed lithological and geothermal interpretation. Lithological and geological maps were used to constrain surface condition and to understand the resistivity ranges of the different lithological units. On the base of resistivity values, lithological units were combined to establish the main litho-resistive units, then modeled at depth, down to achievable investigation depth. This detailed interpretative modeling was also the occasion of recognizing resistivity anomalies within carbonate units, which may possibly represent hydrogeological or hydrothermal bodies. The litho-resitive 3D model is now under investigation to verify how it can represent a viable way to image thermal conductivity variations at depth.

Menghini, A.; Manzella, A.; Viezzoli, A.; Montanari, D.; Maggi, S.



Quasi-Monte Carlo Sampling to improve the Efficiency of Monte Carlo EM  

E-print Network

Quasi-Monte Carlo Sampling to improve the Efficiency of Monte Carlo EM Wolfgang Jank November 17, 2003 Abstract In this paper we investigate an efficient implementation of the Monte Carlo EM al- gorithm based on Quasi-Monte Carlo sampling. The Monte Carlo EM algorithm is a stochastic version

Jank, Wolfgang


Mutagenic effectiveness and efficiency of EMS, DES and gamma-rays in rice  

Microsoft Academic Search

Data on chlorophyll mutation frequency after treatment with EMS, DES and gamma-rays and sequential administration of gamma-rays and the two alkylating agents in three varieties of rice have been used to work out quantitatively the effectiveness and efficiency of each mutagen and combination treatment. For effectiveness, the order is EMS > DES and for efficiency it is EMS > DES

M. L. H. Kaul; A. K. Bhan



Convergence results for the EM approach to mixtures of experts architectures  

Microsoft Academic Search

The Expectation-Maximization (EM) algorithm is an iterative approach to maximum likelihood parameter estimation. Jordan and Jacobs recently proposed an EM algorithm for the mixture of experts architecture of Jacobs, Jordan, Nowlan and Hinton (1991) and the hierarchical mixture of experts architecture of Jordan and Jacobs (1992). They showed empirically that the EM algorithm for these architectures yields significantly faster convergence

Michael I. Jordan; Lei Xu



O ser em metamorfose Jornal Circulao n. 55  

E-print Network

assédio moral quando, em 1912, Kafka escreveu o livro, mas a história serve bem como metáfora para os Samsa, no livro, não desperta de novo humano e morre sozinho, reduzido à condição de inseto, porque não

Floeter, Sergio Ricardo


ISSN 0103-9741 Monografias em Cincia da Computao  

E-print Network

Carlos José Pereira de Lucena Tácio Mauro Pereira de Campos Mônica Priscila Hernandez Moncada-9741 Editor: Prof. Carlos José Pereira de Lucena Novembro, 2009 Um Agente Especialista em Recomendação de Pereira de Lucena, Tácio Mauro Pereira de Campos, Mônica Priscila Hernandez Moncada bneto

Endler, Markus



E-print Network

GEOBULLETIN NOvEmBEr 1sT 2013 - 1 - GeoBulletin is distributed weekly, by E-mail. Contributions are requested! If you have a news item, a request, an announcement etc. email it to or leave it at the office, Room 225 by Noon on Wednesday. WEEKS LECTURE - FALL 2013 Nov. 1 Laura Wallace UT

Carlson, Anders


Learning Active Basis Models by EM-Type Algorithms  

E-print Network

Learning Active Basis Models by EM-Type Algorithms Zhangzhang Si1, Haifeng Gong1,2, Song-Chun Zhu1 scheme for learning image templates of object categories where the learning is not fully supervised. We and orientations to account for the deformations of object shapes. The model can be easily learned when the objects

Wu, Ying Nian


The EM Algorithm February 2/4, 2004  

E-print Network

(energy) and the second term, which does not depend on , is the entropy. · Thus, in the M-step, maximizing optimization easier. Expectation-Maximization (EM) Algorithm · Iterative algorithm with two linked steps: E of a marginal probability: (; x) = log p(x|) = log z p(x, z|) which is the incomplete log likelihood. #12

Roweis, Sam


Fault Tolerant Control for EMS systems with sensor failure  

Microsoft Academic Search

The paper presents a method to recover the performance of an EMS (Electromagnetic suspension) under faulty air gap measurement. The controller is a combination of classical control loops, a Kalman estimator and analytical redundancy (for the air gap signal). In case of a faulty air gap sensor the air gap signal is recovered using the Kalman filter and analytical redundancy.

Konstantinos Michail; Argyrios Zolotas; Roger Goodall; John Pearson



Accurate EM-TV algorithm in PET with low SNR  

Microsoft Academic Search

PET measurements of tracers with a lower dose rate or short radioactive half life suffer from extremely low SNRs. In these cases standard reconstruction methods (OSEM, EM, filtered backprojection) deliver unsatisfactory and noisy results. Here, we propose to introduce nonlinear variational methods into the reconstruction process to make an efficient use of a-priori information and to attain improved imaging results.

Alex Sawatzky; Christoph Brune; Frank Wiibbeling; Thomas Kosters; Klaus Schafers; Martin Burger



Iterative EM Design of an MRI Magnet Using HTS Materials  

Microsoft Academic Search

Conventional superconducting MRI magnet electromagnetic (EM) design involves the critical parameters of the magnet field and dimensional requirements, plus the low temperature superconductor (LTS) wire properties. When using HTS material for an MRI magnet, in addition to the conventional characteristics of a superconductor, the wire and the joint resistance need also to be considered. This is mainly due to the

Minfeng Xu; Michele Ogle; Xianrui Huang; Kathleen Amm; Evangelos T. Laskaris




Microsoft Academic Search

Resumo: O intuito desta exposição é apresentar, com base na análise da experiência da RED- U - Red Estatal de Docencia Universitaria constituída por universidades espanholas, uma reflexão em torno do desenvolvimento profissional do docente universitário no atual contexto de globalização. A referida rede representa um espaço para a difusão e o intercâmbio de políticas, experiências, metodologias e ferramentas utilizadas

Solange Maria Longhi


Cost-Effectiveness Analysis of Helicopter EMS for Trauma Patients  

Microsoft Academic Search

Study objective: To evaluate the cost-effectiveness of helicopter EMS for trauma patients. Methods: We applied a cost-effectiveness analysis from the service provider's perspective to cost and effectiveness estimates. The cost estimates comprise direct operating costs and additional survivors' hospital costs. The effectiveness estimates were calculated with the TRISS methodology from literature sources and data from a cohort of patients transported

Peter A Gearhart; Richard Wuerz; A. Russell Localio



University of Northern British Columbia Posting #12-079EM  

E-print Network

duties, the Residence and Student Life Manager is responsible for the effective management of ResidenceUniversity of Northern British Columbia Posting #12-079EM Residence & Student Life Manager (Regular to a sustainable future. UNBC's main campus is located in Prince George, a city of nearly 80,000 people near

Northern British Columbia, University of


NUMBER: EM 1.00 (NEW) SECTION: Emergency Management  

E-print Network

NUMBER: EM 1.00 (NEW) SECTION: Emergency Management SUBJECT: Emergency Notification System Policy: Michael Amiridis Issued by: Emergency Management I. Policy Per the Higher Education Opportunity Act the Carolina Alert system. a. Emergency Management Coordinator, University of South Carolina Division of Law

Almor, Amit


Leica EM AFS2 Automatic Freeze Substitution System  

E-print Network

" excludes humidity and oxygen · Fast UV polymerization with LED UV lamp Flexibility · Any choice is polymerized under UV light in the EM AFS2 and can be cut and immuno labelled. LED UV lamp FS chamber with new. An integrated LED UV lamp allows immediate polymerization of the samples. Automatic process · One step

Chapman, Michael S.


Hierarchical mixtures of experts and the EM algorithm  

Microsoft Academic Search

We present a tree-structured architecture for supervised learning. The statistical model underlying the architecture is a hierarchical mixture model in which both the mixture coefficients and the mixture components are generalized linear models (GLIMs). Learning is treated as a maximum likelihood problem; in particular, we present an expectation-maximization (EM) algorithm for adjusting the parameters of the architecture. We also develop

Michael I. Jordan; Robert A. Jacobs



Hierarchical Mixtures of Experts and the EM Algorithm  

Microsoft Academic Search

We present a tree-structured architecture for supervised learning. The statistical model underlying the architecture is a hierarchical mixture model in which both the mixture coefficients and the mixture components are generalized linear models (GLIM's). Learning is treated as a maximum likelihood problem; in particular, we present an Expectation-Maximization (EM) algorithm for adjusting the parameters of the architecture. We also develop

Michael I. Jordan; Robert A. Jacobs



An EM algorithm for a semiparametric mixture model  

E-print Network

An EM algorithm for a semiparametric mixture model Laurent Bordes1 Didier Chauveau2 Pierre Marne-la-Vall´ee & CNRS January 2006 Abstract. Recently several authors considered finite mixture models not obvious, and when it occurs, inference methods are rather specific to the mixture model under

Vandekerkhove, Pierre


Symmetry-restrained flexible fitting for symmetric EM maps  

PubMed Central

Summary Many large biological macromolecules have inherent structural symmetry, being composed of a few distinct subunits, repeated in a symmetric array. These complexes are often not amenable to traditional high-resolution structural determination methods, but can be imaged in functionally relevant states using cryo-electron microscopy (cryo-EM). A number of methods for fitting atomic-scale structures into cryo-EM maps have been developed, including the molecular dynamics flexible fitting (MDFF) method. However, quality and resolution of the cryo-EM map are the major determinants of a method’s success. In order to incorporate knowledge of structural symmetry into the fitting procedure, we developed the symmetry-restrained MDFF method. The new method adds to the cryo-EM map-derived potential further restraints on the allowed conformations of a complex during fitting, thereby improving the quality of the resultant structure. The benefit of using symmetry-based restraints during fitting, particularly for medium to low-resolution data, is demonstrated for three different systems. PMID:21893283

Chan, Kwok-Yan; Gumbart, James; McGreevy, Ryan; Watermeyer, Jean M.; Sewell, B. Trevor; Schulten, Klaus



EM Structure-Based Accelerators Working Group Summary  

Microsoft Academic Search

This Working Group (WG) focused on EM Structure-Based Accelerators, which covers a broad area of mechanisms and experiments. Topics covered included dielectric wakefield accelerators (DWA), photonic bandgap accelerators (PBGA), inverse free electron lasers (IFEL), vacuum laser accelerators (VLA), other novel schemes, and supporting analysis and modeling. In addition, this WG was tasked at the Workshop with developing conceptual (strawman) designs

W. D. Kimura; S. M. Lidia



ISO 14001 EMS standard registration decisions among Canadian organizations  

Microsoft Academic Search

This study characterized the costs and benefits associated with adopting ISO 14001 environmental management system (EMS) standard, based on a survey of ISO 14001-registered organizations in Canada. Decision makers are contemplating whether it is necessary to register to one or more of the ISO and other international standards and, if so, which ones. Furthermore, an organization that has registered separate

Emmanuel K. Yiridoe; J. Stephen Clark; Geb E. Marett; Robert Gordon; Peter Duinker



A Science Service Feature 1 WHYTHE"EmHER ?  

E-print Network

A Science Service Feature 1 WHYTHE"EmHER ? Dr. Charles F. Erooks, Secretary, American the plain white f l a g has a dark trh@&aLr f l a g above i t the prophesy is fair and warmer by Science Service Science Service, 1115 Conn. Ave., Washington, D .C . #12;


"Cada ser, em si, carrega o dom de ser capaz de ser feliz" : um estudo de caso baseado em Alfred Adler, Lev Vigotski e González Rey.  

E-print Network

??Dissertação (mestrado)—Universidade de Brasília, Faculdade de Educação, 2011. As crianças que apresentam qualquer marca em seu desenvolvimento, seja um defeito físico, ausência sensorial ou, até… (more)

Batista, Anelice da Silva



Composting of rice straw with effective microorganisms (EM) and its influence on compost quality  

PubMed Central

This study aims to assess the effect of EM application on the composting process of rice straw with goat manure and green waste and to evaluate the quality of both compost treatments. There are two treatment piles in this study, in which one pile was applied with EM and another pile without EM. Each treatment was replicated three times with 90 days of composting duration. The parameters for the temperature, pH, TOC and C/N ratio, show that decomposition of organic matter occurs during the 90-day period. The t-test conducted shows that there is a significant difference between compost with EM and compost without EM. The application of EM in compost increases the macro and micronutrient content. The following parameters support this conclusion: compost applied with EM has more N, P and K content (P?EM. Although the Fe in compost with EM is much higher (P?EM, for Zn and Cu, there is no significant difference between treatments. This study suggests that the application of EM is suitable to increase the mineralization in the composting process. The final resultant compost indicated that it was in the range of the matured level and can be used without any restriction. PMID:23390930



Método numérico das diferenças finitas no domínio do tempo aplicado a ondas Alfvén em plasma astrofísico  

NASA Astrophysics Data System (ADS)

Ondas Alfvén em plasma astrofísico têm sido objeto de intenso estudo nas últimas décadas pelo fato de apresentarem papel importante em muitas áreas de pesquisa na astrofísica. Particularmente são importantes no mecanismo de aquecimento da coroa solar; em ventos estelares; em jatos galácticos e extragalácticos; em discos protoestelares, etc. A formulação para diferenças finitas no domínio do tempo (FDTD), aplicada a plasma magnetizado é desenvolvida para estudo das propriedades de ondas Alfvén em três dimensões (3D-FDTD). O método é aplicado inicialmente a um plasma homogêneo e isotérmico imerso em uma região com campo magnético externo B0, que sofre uma pequena perturbação. Uma vez gerada a onda, esta perturbação é retirada e, então analisamos a evolução temporal das ondas, bem como a forma de seu amortecimento.

Dos Santos, L. C.; Kintopp, J. A.; Jatenco-Pereira, V.; Opher, R.



Environmental Restoration and Waste Management (EM) program: An introduction  

SciTech Connect

This booklet introduces the reader to the mission and functions of a major new unit within the US Department of Energy (DOE): the Office of Environmental Restoration and Waste Management (EM). The Secretary of Energy established EM in November 1989, implementing a central purpose of DOE's first annual Environmental Restoration and Waste Management Five-Year Plan, which had appeared three months earlier. The contents of this booklet, and their arrangement, reflect the annual update of the Five-Year Plan. The Five-Year Plan supports DOE's strategy for meeting its 30-year compliance and cleanup goal. This strategy involves: focusing DOE's activities on eliminating or reducing known or recognized potential risks to worker and public health and the environment, containing or isolating, removing, or detoxifying onsite and offsite contamination, and developing technology to achieve DOE's environmental goals.

Not Available



Superconducting Electromagnetic Suspension (EMS) system for Grumman Maglev concept  

NASA Technical Reports Server (NTRS)

The Grumman developed Electromagnetic Suspension (EMS) Maglev system has the following key characteristics: a large operating airgap--40 mm; levitation at all speeds; both high speed and low speed applications; no deleterious effects on SC coils at low vehicle speeds; low magnetic field at the SC coil--less than 0.35 T; no need to use non-magnetic/non-metallic rebar in the guideway structure; low magnetic field in passenger cabin--approximately 1 G; low forces on the SC coil; employs state-of-the-art NbTi wire; no need for an active magnet quench protection system; and lower weight than a magnet system with copper coils. The EMS Maglev described in this paper does not require development of any new technologies. The system could be built with the existing SC magnet technology.

Kalsi, Swarn S.



Evolução temporal de discos circunstelares em estrelas Be  

NASA Astrophysics Data System (ADS)

A pesquisa do mecanismo que leva uma estrela do tipo Be a perder massa e formar um envelope circunstelar, nomeado como fenômeno Be, é uma questão em aberto, intrigante, e que adquire contornos interessantes em face às informações espectroscópicas de alta resolução. Nesta última década, consolida-se a idéia de que a forma destes envelopes é de tipo discóide, obedecendo a uma lei Kepleriana de velocidades, e mais ainda, recentemente há evidências de que a distribuição de matéria nestes discos pode assumir um caráter de anel. Medidas de algumas dimensões de discos circunstelares puderam ser obtidas pela análise de espectros de alta resolução e alta relação sinal-ruído para as estrelas Be: alpha Eri (HD 10144, B3Vpe), omicron And (HD 217675, B6IIIpe), e eta Cen (HD el972, B1.5Vne), no período dos anos de 1991 a 2001. Alguns modelos clássicos de envelope predizem uma distribuição de massa que decresce suavemente a partir da superfície estelar. Entretanto, considerando que a separação de picos de emissão em perfis de linhas do HeI e H-alpha, alargados por efeitos cinemáticos, é função do raio estelar e da velocidade rotacional projetada (vsini); nossos resultados sugerem a presença de um anel de matéria circunstelar, que aparece logo após a ejeção do material fotosférico, imediatamente acima da superfície estelar, e que se expande para raios maiores ao longo do tempo, eventualmente desconectando-se da superfície por uma região de densidade de matéria mínima. Tais interpretações revivem a idéia de que anéis de matéria circunstelar podem ser os responsáveis por algumas variabilidades em perfis de linhas de emissão, como as variações V/R.

Fernandes, M. V. M.; Leister, N. V.; Levenhagen, R. S.



ISSN 0103-9741 Monografias em Cincia da Computao  

E-print Network

Pereira Sardinha Carlos José Pereira de Lucena Departamento de Informática PONTIFÍCIA UNIVERSIDADE;Monografias em Ciência da Computação, No. 32/05 ISSN: 0103-9741 Editor: Prof. Carlos José Pereira de Lucena * Carolina Howard Felicíssimo, José Alberto Pereira Rodrigues Sardinha, Carlos José de Pereira de Lucena

Endler, Markus


Override problems lead chain to EMS with remote monitor  

SciTech Connect

When R.B. Furniture Co. employees began overriding the Trimax energy management system (EMS) in the company's 61 showrooms, the company shifted to En-Log units for the remaining stores despite the 9- to 22-month payback of the Trimax systems. Remote communications allow monitoring of the En-Log systems and prevent overrides. The case history compares specifications and costs for the two systems. (DCK)

Galvin, C.



EMS users find solutions to voltage-surge problems  

SciTech Connect

The microchips in energy-management systems (EMS) are especially vulnerable to damage due to voltage surges, but the addition of surge suppressors to cut off the peak of spikes at a certain level or the use of fiber-optic cable that transmits light signals instead of electricity can overcome the problem. Users are often unaware that lightning, utility-grid switching, or the shutting down of large equipment can cause surges that garble computer information. (DCK)

Galvin, C.



ISSN 0103-9741 Monografias em Cincia da Computao  

E-print Network

PUC ISSN 0103-9741 Monografias em Ciência da Computação n° 05/06 IPTV Conceitos, Padrões e Soluções Computação, No. 05/06 ISSN: 0103-9741 Editor: Prof. Carlos José Pereira de Lucena Fevereiro, 2006 IPTV ) ! %& % * & + %& %& 1 >1 , 2 Soluções e provedores de serviço de IPTV 2.1 Soluções : %) % %) % 6

Endler, Markus


Da universidade para o mercado de trabalho em onze pases  

E-print Network

Universia está a ser lançado em várias instituições de ensino superior portuguesas. Rede ibero-americana regista por mês 195 mil ofertas ANA BELA FERREIRA Desde quinta-feira que os 23 mil alunos da Universidade a pró-rei- tora, Ana Nunes de Almeida. Ao aderir a esta plataforma, que con- centra não só ofertas

Instituto de Sistemas e Robotica


SEM and TEM Observation of the Surfaces of the Fine-Grained Particles Retrieved from the Muses-C Regio on the Asteroid 25413 Itokawa  

NASA Technical Reports Server (NTRS)

Surface materials on airless solar system bodies exposed to interplanetary space are gradually changed their visible to near-infrared reflectance spectra by the process called "space weathering", which makes the spectra darker and redder. Hapke et al. proposed a model of space weathering: vapor deposition of nanophase reduced iron (npFe(sup 0)) on the surfaces of the grains within the very surface of lunar regolith. This model has been proved by detailed observation of the surfaces of the lunar soil grains by transmission electron microscope (TEM). They demonstrated that npFe(sup 0) was formed by a combination of vapor deposition and irradiation effects. In other words, both micrometeorite impacts and irradiation by solar wind and galactic cosmic ray play roles on the space weathering on the Moon. Because there is a continuum of reflectance spectra from those of Q-type asteroids (almost the same as those of ordinary chondrites) to those of S-type asteroids, it is strongly suggested that reflectance spectra of asteroids composed of ordinary chondrite-like materials were modified over time to those of S-type asteroids due to space weathering. It is predicted that a small amount of npFe(sup 0) on the surface of grains in the asteroidal regolith composed of ordinary chondrite-like materials is the main agent of asteroidal space weathering.

Noguchi, T.; Nakamura, T.; Zolensky, Michael E.; Tanaka, M.; Hashimoto, T.; Konno, M.; Nakato, A.; Ogami, T.; Fujimura, A.; Abe, M.; Yada, T.; Mukai, T.; Ueno, M.; Okada, T.; Shirai, K.; Ishibashi, Y.; Okazaki, R.




Microsoft Academic Search

The paper presents opportunities of the phenomenological approach towards the Belarusian-Polish-Lithuanian borderlands. Such approach is based upon the prin- ciples of understanding of social reality elaborated in phenomenology (E. Husserl, M. Heidegger) and phenomenological sociology (A. Schutz) and presents a dif- ferent view of the borderlands as compared with the traditional (classical) socio- logy. The social and cultural space of

Mikalai Biaspamiatnych



Lettuce Costunolide Synthase (CYP71BL2) and Its Homolog (CYP71BL1) from Sunflower Catalyze Distinct Regio- and Stereoselective Hydroxylations in Sesquiterpene Lactone Metabolism*  

PubMed Central

Sesquiterpene lactones (STLs) are terpenoid natural products possessing the ?-lactone, well known for their diverse biological and medicinal activities. The occurrence of STLs is sporadic in nature, but most STLs have been isolated from plants in the Asteraceae family. Despite the implication of the ?-lactone group in many reported bioactivities of STLs, the biosynthetic origins of the ?-lactone ring remains elusive. Germacrene A acid (GAA) has been suggested as a central precursor of diverse STLs. The regioselective (C6 or C8) and stereoselective (? or ?) hydroxylation on a carbon of GAA adjacent to its carboxylic acid at C12 is responsible for the ?-lactone formation. Here, we report two cytochrome P450 monooxygenases (P450s) capable of catalyzing 6?- and 8?-hydroxylation of GAA from lettuce and sunflower, respectively. To identify these P450s, sunflower trichomes were isolated to generate a trichome-specific transcript library, from which 10 P450 clones were retrieved. Expression of these clones in a yeast strain metabolically engineered to synthesize substrate GAA identified a P450 catalyzing 8?-hydroxylation of GAA, but the STL was not formed by spontaneous lactonization. Subsequently, we identified the closest homolog of the GAA 8?-hydroxylase from lettuce and discovered 6?-hydroxylation of GAA by the recombinant enzyme. The resulting 6?-hydroxy-GAA spontaneously undergoes a lactonization to yield the simplest form of STL, costunolide. Furthermore, we demonstrate the milligram per liter scale de novo synthesis of costunolide using the lettuce P450 in an engineered yeast strain, an important advance that will enable exploitation of STLs. Evolution and homology models of these two P450s are discussed. PMID:21515683

Ikezawa, Nobuhiro; Gopfert, Jens Christian; Nguyen, Don Trinh; Kim, Soo-Un; O'Maille, Paul E.; Spring, Otmar; Ro, Dae-Kyun



Lewis acid promoted construction of chromen-4-one and isoflavone scaffolds via regio- and chemoselective domino Friedel-Crafts acylation/Allan-Robinson reaction.  


A facile and efficient synthesis of chromen-4-one and isoflavone frameworks is achieved by the domino C-acylation/O-acylation/aldolization sequence. This operationally simple one-pot elegant strategy provides structurally unique chromen-4-ones and isoflavones directly from phenols via concomitant formation of multiple C-C and C-O bonds in a single operation. The outcomes of the buttressing effect, substituent dependence, and catalyst and solvent specificity during the course of the Friedel-Crafts acylation reactions are demonstrated and supported by fitting experiments. PMID:25299841

Chanda, Tanmoy; Chowdhury, Sushobhan; Koley, Suvajit; Anand, Namrata; Singh, Maya Shankar



Regio- and stereoselective hydroxylation of 10-undecenoic acid with a light-driven P450 BM3 biocatalyst yielding a valuable synthon for natural product synthesis.  


We report herein the selective hydroxylation of 10-undecenoic acid with a light-activated hybrid P450 BM3 enzyme. Under previously developed photocatalytic reaction conditions, only a monohydroxylated product is detected by gas chromatography. Hydroxylation occurs exclusively at the allylic position as confirmed from a synthesized authentic standard. Investigation into the stereochemistry of the reaction indicates that the R enantiomer is obtained in 85% ee. The (R)-9-hydroxy-10-undecenoic acid obtained enzymatically is a valuable synthon en route to various natural products further expanding the light-activated P450 BM3 biocatalysis and highlighting the advantages over traditional methods. PMID:24938497

Kato, Mallory; Nguyen, Daniel; Gonzalez, Melissa; Cortez, Alejandro; Mullen, Sarah E; Cheruzel, Lionel E



Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis.  


The polyene macrolide antibiotic filipin is widely used as a probe for cholesterol and a diagnostic tool for type C Niemann-Pick disease. Two position-specific P450 enzymes are involved in the post-polyketide modification of filipin during its biosynthesis, thereby providing molecular diversity to the "filipin complex." CYP105P1 and CYP105D6 from Streptomyces avermitilis, despite their high sequence similarities, catalyze filipin hydroxylation at different positions, C26 and C1', respectively. Here, we determined the crystal structure of the CYP105P1-filipin I complex. The distal pocket of CYP105P1 has the second largest size among P450 hydroxylases that act on macrolide substrates. Compared with previously determined substrate-free structures, the FG helices showed significant closing motion on substrate binding. The long BC loop region adopts a unique extended conformation without a B' helix. The binding site is essentially hydrophobic, but numerous water molecules are involved in recognizing the polyol side of the substrate. Therefore, the distal pocket of CYP105P1 provides a specific environment for the large filipin substrate to bind with its pro-S side of position C26 directed toward the heme iron. The ligand-free CYP105D6 structure was also determined. A small sub-pocket accommodating the long alkyl side chain of filipin I was observed in the CYP105P1 structure but was absent in the CYP105D6 structure, indicating that filipin cannot bind to CYP105D6 with a similar orientation due to steric hindrance. This observation can explain the strict regiospecificity of these enzymes. PMID:20375018

Xu, Lian-Hua; Fushinobu, Shinya; Takamatsu, Satoshi; Wakagi, Takayoshi; Ikeda, Haruo; Shoun, Hirofumi



Isotopic analysis of lead present in the cinnabar of Roman wall paintings from the Xth Regio “(Venetia et Histria)” by ICP-MS  

Microsoft Academic Search

The analysis of Roman wall paintings coming from Verona, Vicenza, Padova, Pordenone and Trieste evidentiated the presence of cinnabar.In this work, the isotopic composition 206Pb, 207Pb and 208Pb of trace of lead present in cinnabar is reported, via ICP-MS measurements. The isotopic ratio values are compared with the values obtained from samples coming from Roman wall paintings of Pompeii and

G. A. Mazzocchin; P. Baraldi; C. Barbante



Regio- and stereospecificity in the oxygenation of arachidonic acid catalyzed by Leu597 mutants of rabbit 15-lipoxygenase: a QM/MM study.  


We combined quantum mechanics/molecular mechanics calculations with molecular dynamics simulations to study the addition of O2 to the pentadienyl radical of arachidonic acid (AA) catalyzed by the Leu597Val and Leu597Ala mutants of rabbit 15-lipoxygenase (15-rLO). In the Leu597Val mutant, the addition of O2 to C15 of AA is the predominant path, although it reduces the C15/C11 product ratio by almost ten times with respect to the wildtype enzyme. The S stereochemistry is kept. Mutation to Ala causes just the opposite effect: regiospecificity favoring addition to C15 is somewhat sharper than that in the wildtype, but the stereochemistry is R. This is because the extra space created by the mutation to Ala is big enough for AA to move so that it can adopt an alternative binding mode, and this opens new feasible paths for the attack of O2 . So, we showed that the Leu597Ala mutant of 15r-LO works as an aspirin-acetylated cyclooxygenase-2, which makes 15-(R)- hydroperoxyeicosatetraenoic acid. PMID:24753045

Suardíaz, Reynier; Masgrau, Laura; Lluch, José M; González-Lafont, Angels



Synthesis of unnatural amino acids via microwave-assisted regio-selective one-pot multi-component reactions of sulfamidates  

EPA Science Inventory

Synthesis of triazole-based unnatural amino acids, triazole bisaminoacids and ß-amino triazole has been described via stereo and regioselective one-pot multi-component reaction of sulfamidates, sodium azide, and alkynes under MW irradiation conditions. The developed method is app...


Origins of Regio- and Stereochemistry in Type 2 Intramolecular N-Acylnitroso Diels-Alder Reactions: A Computational Study of Tether Length and Substituent Effects  

PubMed Central

Quantum mechanical calculations have been used to investigate type 2 intramolecular Nacylnitroso Diels–Alder reactions. Experimentally observed regioselectivities and diastereoselectivities of these reactions have been reproduced using B3LYP/6-31+G(d) DFT calculations. The factors that govern selectivity (i.e. tether length, tether substitution and diene substitution) were systematically investigated. Tethers less than 6 carbon atoms lead to 1,3 regioisomers due to conformational restrictions. Substituents on the tether lead to diastereoselective outcomes dictated by transannular interactions in the transition states. The modest diastereoselectivity of diene-substituted substrates is rationalized as arising from reduction of eclipsing interactions in the flattened diene transition states. This method should prove valuable for planning syntheses involving type 2 intramolecular Diels–Alder reactions. PMID:23477601

Cleary, Leah; Mak, Victor W.; Rychnovsky, Scott D.; Shea, Kenneth J.; Sizemore, Nicholas



Perda de massa em ventos empoeirados de estrelas supergigantes  

NASA Astrophysics Data System (ADS)

Em praticamente todas as regiões do diagrama HR, as estrelas apresentam evidências observacionais de perda de massa. Na literatura, pode-se encontrar trabalhos que tratam tanto do diagnóstico da perda de massa como da construção de modelos que visam explicá-la. O amortecimento de ondas Alfvén tem sido utilizado como mecanismo de aceleração de ventos homogêneos. Entretanto, sabe-se que os envelopes de estrelas frias contêm grãos sólidos e moléculas. Com o intuito de estudar a interação entre as ondas Alfvén e a poeira e a sua conseqüência na aceleração do vento estelar, Falceta-Gonçalves & Jatenco-Pereira (2002) desenvolveram um modelo de perda de massa para estrelas supergigantes. Neste trabalho, apresentamos um estudo do modelo acima proposto para avaliar a dependência da taxa de perda de massa com alguns parâmetros iniciais como, por exemplo, a densidade r0, o campo magnético B0, o comprimento de amortecimento da onda L0, seu fluxo f0, entre outros. Sendo assim, aumentando f0 de 10% a partir de valores de referência, vimos que aumenta consideravelmente, enquanto que um aumento de mesmo valor em r0, B0 e L0 acarreta uma diminuição em .

Vidotto, A. A.; Jatenco-Pereira, V.



Hydration-layer models for cryo-EM image simulation  

PubMed Central

To compare cryo-EM images and 3D reconstructions with atomic structures in a quantitative way it is essential to model the electron scattering by solvent (water or ice) that surrounds protein assemblies. The most rigorous method for determing the density of solvating water atoms for this purpose has been to perform molecular-dynamics (MD) simulations of the protein-water system. In this paper we adapt the ideas of bulk-water modeling that are used in the refinement of X-ray crystal structures to the cryo-EM solvent-modeling problem. We present a continuum model for solvent density which matches MD-based results to within sampling errors. However, we also find that the simple binary-mask model of Jiang and Brünger (1994) performs nearly as well as the new model. We conclude that several methods are now available for rapid and accurate modeling of cryo-EM images and maps of solvated proteins. PMID:22609687

Shang, Zhiguo; Sigworth, Fred J.



The US DOE-EM International Program - 13004  

SciTech Connect

The U.S. Department of Energy (DOE) Office of Environmental Management (EM) conducts international collaboration activities in support of U.S. policies and objectives regarding the accelerated risk reduction and remediation of environmental legacy of the nations' nuclear weapons program and government sponsored nuclear energy research. The EM International Program supported out of the EM Office of the Associate Principal Deputy Assistant Secretary pursues collaborations with foreign government organizations, educational institutions and private industry to assist in identifying technologies and promote international collaborations that leverage resources and link international experience and expertise. In fiscal year (FY) 2012, the International Program awarded eight international collaborative projects for work scope spanning waste processing, groundwater and soil remediation, deactivation and decommissioning (D and D) and nuclear materials disposition initiatives to seven foreign organizations. Additionally, the International Program's scope and collaboration opportunities were expanded to include technical as well as non-technical areas. This paper will present an overview of the on-going tasks awarded in FY 2012 and an update of upcoming international activities and opportunities for expansion into FY 2013 and beyond. (authors)

Elmetti, Rosa R.; Han, Ana M.; Williams, Alice C. [Department of Energy, Office of Environmental Management, 1000 Independence Ave. SW, Washington, DC 20585 (United States)] [Department of Energy, Office of Environmental Management, 1000 Independence Ave. SW, Washington, DC 20585 (United States)



Improving EM&V for Energy Efficiency Programs (Fact Sheet)  

SciTech Connect

This fact sheet describes the objectives of the U.S. Department of Energy Uniform Methods Project to bring consistency to energy savings calculations in U.S. energy efficiency programs. The U.S. Department of Energy (DOE) is developing a framework and a set of protocols for determining gross energy savings from energy efficiency measures and programs. The protocols represent a refinement of the body of knowledge supporting energy efficiency evaluation, measurement, and verification (EM&V) activities. They have been written by technical experts within the field and reviewed by industry experts. Current EM&V practice allows for multiple methods for calculating energy savings. These methods were developed to meet the needs of energy efficiency program administrators and regulators. Although they served their original objectives well, they have resulted in inconsistent and incomparable savings results - even for identical measures. The goal of the Uniform Methods Project is to strengthen the credibility of energy savings determinations by improving EM&V, increasing the consistency and transparency of how energy savings are determined.

Not Available



Retrospectively exploring the importance of items in the decision to leave the emergency medical services (EMS) profession and their relationships to life satisfaction after leaving EMS and likelihood of returning to EMS.  


An exit survey was returned by a sample of 127 respondents in fully compensated positions who left the EMS profession, most within 12 months prior to filling out the exit survey. A very high percentage continued to work after leaving EMS. Respondents were asked to rate the importance of each of 17 items in affecting their decision to leave EMS. A higher than anticipated response to a "not applicable" response choice affected the usability of 8 of these items. Nine of the 17 items had at least 65 useable responses and were used for further analysis. Within these 9, stress/burnout and lack of job challenges had the highest importance in affecting the decision to leave EMS, while desire for better pay and benefits had the lowest importance. Desire for career change was positively related to life satisfaction after leaving EMS and negatively related to likelihood of returning to EMS. Stress/burnout was positively related to life satisfaction after leaving EMS. Study limitations and future research issues are briefly discussed. PMID:21695362

Blau, Gary; Chapman, Susan



Inhomogeneous Media 3D EM Modeling with Integral Equation Method  

NASA Astrophysics Data System (ADS)

In general, only the half space of earth is considered in electromagnetic exploration. However, for the long bipole source, because the length is close to the height of ionosphere and also most offsets between source and receivers are equal or larger than the height of ionosphere, the effect of ionosphere on the electromagnetic (EM) field should be considered when observation is carried at a very far (about several thousands kilometers) location away from the source. At this point the problem becomes one which should contain ionosphere, atmosphere and earth that is “earth-ionosphere” case. There are a few of literatures to report the electromagnetic field results which is including ionosphere, atmosphere and earth media at the same time. We firstly calculate the electromagnetic fields with the traditional controlled source (CSEM) configuration using integral equation (IE) method for a three layers earth-ionosphere model. The modeling results agree well with the half space analytical results because the effect of ionosphere for this small scale bipole source can be ignorable. The comparison of small scale three layers earth-ionosphere modeling and half space analytical resolution shows that the IE method can be used to modeling the EM fields for long bipole large offset configuration. In order to discuss EM fields’ characteristics for complicate earth-ionosphere media excited by long bipole source in the far-field and wave-guide zones, we first modeled the decay characters of electromagnetic fields for three layers earth-ionosphere model. Because of the effect of ionosphere, the earth-ionosphere electromagnetic fields’ decay curves with given frequency show that there should be an extra wave guide zone for long bipole artificial source, and there are many different characters between this extra zone and far field zone. They are: 1) the amplitudes of EM fields decay much slower; 2) the polarization patterns change; 3) the positions better to measure Zxy and Zyx change; 4) there exits the polarization ellipse of electric and magnetic fields; 5) the long axis direction of the polarization ellipse in wave guide zone changes comparing to quasi static EM fields. In order to further model the EM fields for complex inhomogeneous media, we conducted the EM fields modeling for Biyang depressed basin of China. The bottom depth of the oil basin is about 8km. We added one ionosphere layer with thickness 100km and resistivity 104 Ohm-m and one atmosphere layer with thickness 100km and resistivity 1014 Ohm-m over the solid earth surface during the forward modeling. For easily to compare with the 2D seismic exploration result, we conducted the apparent resistivity modeling of equatorial array for the same survey line as seismic did for an 50km long bipole source with offset 400km and the same frequencies as that used for above three layers model. The modeling apparent resistivity pseudo-section has clearly shown the oil basin geology structure.

di, Q.; Wang, R.; An, Z.; Fu, C.; Xu, C.




E-print Network

-80, 2011. Disponível em: Leia-162, 2000. Disponível em: 5 diferentes abordagens. Rev. Ensaio, v.13, n.3, p.67-80, 2011. Disponível em:

Maier, Rudolf Richard


0.5setgray00.5setgray1 Determinao de coeficientes em equaes  

E-print Network

de Imagens em Medicina Nuclear · SPECT ­ Single Photon Emission Tomography, ­ p. 13/7 #12;Técnicas para Geração de Imagens em Medicina Nuclear · SPECT ­ Single Photon Emission Tomography, · PET ­ Positron Emission Tomograpy; ­ p. 13/7 #12;Técnicas para Geração de Imagens em Medicina Nuclear · SPECT

Cipolatti, Rolci



E-print Network

1 UNIVERSIDADE DE BRASÍLIA PROGRAMA DE RESID�NCIA M�DICO VETERINÁRIA EM ANATOMIA PATOL�GICA ANATOMIA PATOL�GICA VETERINÁRIA PARA O PRIMEIRO PERÍODO LETIVO DE 2011 1. PRE�MBULO 1.1 O Presidente da Veterinária em Anatomia Patológica Veterinária, em conformidade com as exigências do Regulamento deste

Maier, Rudolf Richard


EmNets 2006 Life Under your Feet 1 Life Under your Feet  

E-print Network

EmNets 2006 Life Under your Feet 1 Life Under your Feet: A Wireless Soil Ecology Sensor Network R the Beginning... EmNets 2006 Life Under your Feet 2 · The Cast · An ecologist: Katalin Szlavecz · An undergrad Step EmNets 2006 Life Under your Feet 3 · The sensors were thoroughly tested in the lab · 2 out of 6

Amir, Yair



E-print Network


Maier, Rudolf Richard


EMS-CO2 Welding: A New Approach to Improve Droplet Transfer Characteristics and Welding Formation  

Microsoft Academic Search

In this article, to improve the stability of droplet transfer and reduce the spatter of pure carbon dioxide gas shield welding (CO2 welding), we propose a new welding method called EMS-CO2 welding by applying an additional longitudinal electromagnetic field to a CO2 welding process (abbr. EMS-CO2 welding). The characteristics of droplet transfer, welding formation and microstructure between EMS-CO2 welding and

Jian Luo; Qian Luo; Xiangjie Wang; Xiaochuan Wang



Melasma extra-facial : avaliação clínica, histopatológica e imuno-histoquímica em estudo caso-controle.  

E-print Network

??Fundamentos: O melasma extra-facial é dermatose freqüente na prática clínica dermatológica. Apresenta características especiais em relação tanto aos aspectos clínicos como aos prováveis fatores etiopatogênicos.… (more)

Clarice Gabardo Ritter



ADMINISTRATION AND COLLEGE MASTERS 343342 ADMINISTRATION Emergency Medical Service (EMS) .................................................... Bill Taylor  

E-print Network

ADMINISTRATION AND COLLEGE MASTERS 343342 ADMINISTRATION Emergency Medical Service (EMS .................................................. Adria Baker Intramural Sports. Lieberman Media Relations and Information ................................................ Margot Dimond

Richards-Kortum, Rebecca


Administração peridural de morfina ou tramadol em cães: efeito analgésico e cardiorespiratório.  

E-print Network

??Objetivou-se com este estudo duplo cego avaliar o efeito analgésico e cardiorrespiratório da morfina ou tramadol quando utilizados via peridural, em cadelas submetidas à ovariossalpingohisterectomia… (more)

Celso Sawaya Neves



General 4-week toxicity study with EMS in the rat.  


In this subacute toxicity study, ethyl methanesulfonate (EMS) was administered daily by oral gavage to SPF-bred Wistar rats of both sexes at dose levels of 20, 60 and 180/120 mg/kg body weight (bw)/day for a period of 28 days (for 19 days in the high-dose group). A control group was treated similarly with the vehicle, bidistilled water, only. The groups comprised 10 animals per sex, which were sacrificed after 28 days, respectively 19 days in the high-dose group, of treatment. Additional five rats per sex and group were treated accordingly and then allowed a 14 days treatment-free recovery period. Additional six rats per sex and group (three rats per sex in the control group) were treated accordingly and used for hemoglobin adduct analysis after EMS exposure. All animals survived until their scheduled necropsy. Treatment with EMS had a direct dose-dependent effect on food consumption and consequently on body weight at doses > or =20mg/kgbw/day in male rats and at > or =60 mg/kgbw/day in females rats. Hence, treatment with the high dose of 180 mg/kgbw/day had to be interrupted for 9 days after which, the animals were re-dosed at 120 mg/kgbw/day. This dose was also poorly tolerated over the remaining two treatment weeks causing again a marked reduction in food consumption and body weight. A dose of 60 mg/kgbw/day was moderately tolerated over 4 weeks treatment with mean daily food consumption and body weight distinctly lower than in controls. Primary targets of systemic toxicity were the hematopoietic system, thymolymphatic system and sexual organs. Characteristic changes in hematology parameters were decreased red blood cell counts, hematocrit, and hemoglobin concentration. White blood cell counts were also decreased due to reduced lymphocyte and granulocyte populations of each fraction. The corresponding histopathology findings were fatty atrophy of bone marrow and minimal hypocellularity of the white pulp of the spleen. Similarly, treatment with EMS caused an involution of the thymolymphatic system characterized by decreased organ weight of thymus, lymph nodes, and spleen microscopically associated with atrophy of the thymus and hypocellularity of Peyer's patches, lymph nodes and the white pulp of the spleen. The effects on sexual organs included lower organ weight/reduced size for testes, epididymides, seminal vesicles, prostate, and uterus. Tubular atrophy, single cell necrosis of the germ cells and in epididymides reduced spermatozoa were recorded microscopically. The described findings occurred at doses of 60 and 180/120 mg/kgbw/day and were dose-dependent with regard to incidence and severity. Other target organs were the pancreas (acinar cell vacuolation), thyroid gland (follicular cell hypertrophy), and salivary gland (secretory depletion of convoluted ducts). The systemic exposure to EMS was monitored by hemoglobin ethylvaline adduct measurement. The concentration of hemoglobin ethylvaline adducts was linear with the dose and accumulated 11-26-fold over the treatment period. In summary, decreases in food consumption and body weight were the dose-limiting effects of treatment with EMS. Organ toxicity was characterized by depression of cell proliferation (hematopoiesis and spermatogenesis) and changes suggestive of reduced metabolism and/or physiological imbalances (e.g. thymolymphatic system and thyroid gland) without signs of inflammatory or necrotic lesions. For some findings, especially the effects on the thymolymphatic system and sexual organs, it cannot be excluded that starvation-like condition contributed to the occurrence of such changes. The low dose of 20 mg/kgbw/day was basically free of adverse effects despite of a clear evidence for hemoglobin adducts. PMID:19442710

Pfister, Thomas; Eichinger-Chapelon, Anne



Transmission characteristics of EM wave in a finite thickness plasma  

NASA Astrophysics Data System (ADS)

One of the key factors for solving the problems of re-entry communication interruption is electromagnetic (EM) wave transmission characteristics in a plasma. Theoretical and experimental studies were carried out on specific transmission characteristics for different plasma sheath characteristic under thin sheath condition in re-entry state. The paper presents systematic studies on the variations of wave attenuation characteristics versus plasma sheath thickness L, collision frequency ?, electron density n e and wave working frequency f in a ? 800mm high temperature shock tube. In experiments, L is set to 4 cm and 38 cm. ? is 2 GHz and 15 GHz. n e is from 1×1010 cm-3 to 1×1013 cm-3, and f is set to 2, 5, 10, 14.6 GHz, respectively. Meanwhile, Wentzel-Kramers-Brillouin (WKB) and finite-difference time-domain (FDTD) methods are adopted to carry out theoretical simulation for comparison with experimental results. It is found that when L is much larger than EM wavelength ? (thick sheath) and ? is large, the theoretical result is in good agreement with experimental one, when sheath thickness L is much larger than ?, while ? is relatively small, two theoretical results are obviously different from the experimental ones. It means that the existing theoretical model can not fully describe the contribution of ?. Furthermore, when L and ? are of the same order of magnitude (thin sheath), the experimental result is much smaller than the theoretical values, which indicates that the current model can not properly describe the thin sheath effect on EM attenuation characteristics.

Zhu, Nai-Yi; Huang, Li-Shun; Wu, Bin; Yu, Xi-Long; Wu, Run-Hui; Meng, Gang; Ren, Ai-Min; Hu, Xin-Tian



Epidemiology of major incidents: an EMS study from Pakistan  

PubMed Central

Background A major incident is defined as an event that owing to the number of casualties has the potential to overwhelm the available resources. This paper attempts to describe the incidence and epidemiology of major incidents dealt with by a government-run emergency medical service (EMS) in the Punjab province of Pakistan, a developing country in South Asia. A major incident in this EMS is defined as any incident that produces three or more patients, or any incident in which extraordinary resources are needed. Methods All the calls received by an EMS Rescue 1122 were studied over a 6-month period. Calls that were defined as major incidents were identified, and further details were sought from the districts regarding these incidents. Questions specifically asked were the type of incident, time of the incident, response time for the incident, the resources needed, and the number of dead and injured casualties. Retrospective data were collected from the submitted written reports. Results Road traffic crashes (RTCs) emerged as the leading cause of a major incident in the province of Punjab and also led to the greatest number of casualties, followed by fire incidents. The total number of casualties was 3,380, out of which 73.7% were RTC victims. There was a high rate of death on the scene (10.4%). Certain other causes of major incidents also emerged, including violence, gas explosions and drowning. Conclusion Road traffic crashes are the most common cause of a major incident in developing countries such as Pakistan. Injury prevention initiatives need to focus on RTCs. PMID:21798011



A compulsator driven rapid-fire EM-gun  

SciTech Connect

A compulsator-driven railgun is an attractive alternative to the homopolar generator-inductor-switch configuration, especially for repetitive duty. A conceptual design of a rapid-fire EM-gun system is presented. The generator is sized to accelerate a 0.08-kg projectile to 2 to 3 km/s at a 60 pulse-per-second repetition rate. Initial design parameters are discussed, and example current and velocity waveforms are given. The generator is discharged at the proper phase angle to provide a current zero just as the projectile exits the muzzle of the railgun.

Pratap, S.B.; Bird, W.L.



Hospital picks EMS from 3 guaranteed savings bids  

SciTech Connect

A Wheeling, WV medical center stipulated $54,000 guaranteed annual savings from all bidders when it selected an MCC Powers System 600 energy management system (EMS) from among several bidders. A DOE grant will reduce the payback period to one year. A staff energy audit was the basis for the guaranteed savings figure. Programming ease and the ability to display building systems were positive features of the System 600 besides the low bid, but visits to other facilities using the system were a major factor in the decision. (DCK)

Galvin, C.



SEI: Junior E&M I Course Materials - Electrodynamics  

NSDL National Science Digital Library

This is a collection of resources for teaching electrodynamics. Included are homework questions, concept tests, student tutorials, and information about common student difficulties in the topic and ways to address these difficulties. This material was developed as part of a education research-based course transformation for junior level E&M. All of the resources developed for this course are available, sorted by individual topic and type, at Because this topic is not typically taught in depth in the courses used in developing these course materials, these materials are less complete than the other sections.

Pollock, Steven J.; Chasteen, Stephanie V.



SEI: Junior E&M I Course Materials - Math Fundamentals  

NSDL National Science Digital Library

This is a collection of resources for teaching mathematical fundamentals of electro- and magnetostatics constructed over the course of four semesters of a transformed junior-level Electricity and Magnetism course. Included are homework questions, concept tests, and information about common student difficulties in the topic and ways to address these difficulties. This material was developed as part of a education research-based course transformation for junior level E&M. All of the resources developed for this course are available, sorted by individual topic and type, at

Pollock, Steven J.; Chasteen, Stephanie V.



Aristarchus's <em>On the Sizes and Distances of the Sun and the Moonem>: Greek and Arabic Texts  

NASA Astrophysics Data System (ADS)

In the 1920s, T. L. Heath pointed out that historians of mathematics have "given too little attention to Aristarchus". This is still true today. The Greek text of Aristarchus's On the Sizes and Distances of the Sun and the Moonem> has received little attention; the Arabic editions virtually none. Much of what this text has to tell us about ancient and medieval mathematics and the mathematical sciences has gone unnoticed. It should be taken as an important source for our understanding of the mathematical sciences of the early Hellenistic period.

Berggren, J. L.; Sidoli, N.



Efeitos da suplementação aguda de aspartato de arginina na fadiga muscular em voluntários treinados  

Microsoft Academic Search

RESUMO A atividade física influi em mecanismos específicos responsá- veis pela redução da produção de força e conseqüentemente à fadiga. A preocupação em melhorar o desempenho físico tem sido propostos; observamos que estudos dão atenção para reduzir acú- mulos dos metabólitos que diminuem a fadiga durante o exercício físico intenso, usando aminoácidos conhecidos por induzir mudan- ças metabólicas, entre eles

Ricardo Pombo Sales; Carlos Eduardo César Miné; Andréia Dellú Franco; Érika Lima Rodrigues; Renato de Souza e Silva; José Carlos Cogo; Rodrigo A. B. Lopes-Martins; Rodrigo Lazo Osorio; Wellington Ribeiro



On the EM Algorithm and Bootstrap Approach Combination for Improving Satellite Image Fusion  

Microsoft Academic Search

This paper discusses EM algorithm and Bootstrap approach combination applied for the improvement of the satellite image fusion process. This novel satellite image fusion method based on estimation theory EM algorithm and reinforced by Bootstrap approach was successfully implemented and tested. The sensor images are firstly split by a Bayesian segmentation method to determine a joint region map for the

Tijani Delleji; Mourad Zribi; Ahmed Ben



A redução dos níveis de cortisol sanguíneo através da técnica de relaxamento progressivo em nadadores  

Microsoft Academic Search

Reduction of blood cortisol levels through the progres- sive relaxation technique in swimmers Objetivo: Analisar os efeitos da técnica de relaxamento progressivo na redução\\/controle dos níveis de cortisol san- guíneo em nadadores durante determinado período de trei- namentos. Metodologia: Nadadores de ambos os sexos (n = 23) foram divididos em dois grupos: experimental - GE (n = 11), submetido a

Maurício Gattás; Bara Filho; Luiz Carlos Scipião Ribeiro; Renato Miranda; Mônica Tavares Teixeira



Method for evaluating compatibility of commercial electromagnetic (EM) microsensor tracking systems with surgical and imaging tables  

NASA Astrophysics Data System (ADS)

Electromagnetic (EM) tracking systems have been successfully used for Surgical Navigation in ENT, cranial, and spine applications for several years. Catheter sized micro EM sensors have also been used in tightly controlled cardiac mapping and pulmonary applications. EM systems have the benefit over optical navigation systems of not requiring a line-of-sight between devices. Ferrous metals or conductive materials that are transient within the EM working volume may impact tracking performance. Effective methods for detecting and reporting EM field distortions are generally well known. Distortion compensation can be achieved for objects that have a static spatial relationship to a tracking sensor. New commercially available micro EM tracking systems offer opportunities for expanded image-guided navigation procedures. It is important to know and understand how well these systems perform with different surgical tables and ancillary equipment. By their design and intended use, micro EM sensors will be located at the distal tip of tracked devices and therefore be in closer proximity to the tables. Our goal was to define a simple and portable process that could be used to estimate the EM tracker accuracy, and to vet a large number of popular general surgery and imaging tables that are used in the United States and abroad.

Nafis, Christopher; Jensen, Vern; von Jako, Ron



Presença de dentes permanentes irrompidos em escolares da região metropolitana de Porto Alegre  

Microsoft Academic Search

RESUMO Foi realizada uma pesquisa de campo em duas escolas da rede pública estadual de Porto Alegre, com a finalidade de verificar a presença de dentes permanentes irrompidos em crian- ças com faixa etária entre seis a dez anos. Foram examinadas 327 crianças, considerando as variáveis de idade, sexo e raça. Não foi observada diferença significativa para a época de

Karine Squeff; Guilherme Pessoa Cerveira; Luciane Quadrado Closs; Jose Antônio Bosio


Prevalência de sobrepeso\\/obesidade em crianças e adolescentes com constipação crônica funcional  

Microsoft Academic Search

RESUmO Objetivo: Avaliar a prevalência do sobrepeso\\/obesidade em um grupo de crianças com constipação crônica funcional. Métodos: Estudo retrospectivo com 257 crianças de dois a 15 anos com constipação crônica funcional diag- nosticada segundo critérios de Roma II, atendidas con- secutivamente em clínica terciária de gastroenterologia pediátrica. Informações demográficas, clínicas, diagnós - ticas e antropométricas foram obtidas de prontuários. O

Francisca Teresa V. Faleiros; Cristiane Camargo Omae; Cristiane Yoshie Nakazawa; Mary de Assis Carvalho; Nilton Carlos Machado



Competência social e empatia: um estudo sobre resiliência com crianças em situação de pobreza  

Microsoft Academic Search

Social competence and empathy: Study about resilience with children in poverty Resumo O objetivo desse estudo foi avaliar a competência social e a empatia em crianças escolares que vivem em situação de po- breza. Participaram da pesquisa 100 crianças, de ambos os sexos, com idades entre seis e nove anos. Os instrumentos utilizados foram o Teste das Histórias Incompletas (THI)

Alessandra Marques Cecconello; Sílvia Helena Koller



2.5D EM modeling in TIV conductive media Torgeir Wiik  

E-print Network

2.5D EM modeling in TIV conductive media Torgeir Wiik , Bjørn Ursin and Ketil Hokstad, Norwegian domain EM model- ing in conductive media, i.e. in media which are assumed invariant in one direction. Further, we consider media which are transversely isotropic in the vertical direction 1 #12;(TIV), thus

Ursin, Bjørn


Uterus Image Segmentation Using Multi-feature EM Algorithm Based on Gabor Filter  

Microsoft Academic Search

In this work the image is segmented effectively based on texture feature by reducing the noise. For effective image segmentation Expectation-Maximization (EM) algorithm based on Gabor filter is used. The EM algorithm is applied on 2D Ultrasonic image of uterus and tested. The Gabor function has been recognized by its multiresolution properties and the precision of locating the texture features

S. Malarkhodi; R. S. D. W. Banu




Microsoft Academic Search

A cidade de Maceió em Alagoas constitui uma cidade litorânea da Região Nordeste do Brasil dotada de beleza natural tais como praias e lagoas, as quais constituem atrativos para o turismo tanto nacional como internacional. Todavia, nesta o crescimento do setor turístico tem sido afetado pela poluição dos recursos ambientais, mais especificamente o despejo do esgoto em praias e lagoas.

Eliane Aparecida Pereira De Abreu; Agnaldo Gomes da Silva; Gilberto Gomes Da Silva Junior; Rebecca Suzannah Nascimento De Melo



BWR loss-of-coolant accident analysis capability of the WRAP-EM system  

Microsoft Academic Search

The modular computational system known as the Water Reactor Analysis Package (WRAP) has been extended to provide the computational tools required to perform a complete analysis of LOCAs in BWRs. The new system is known as the WRAP-EM (Evaluation Model) system and will be used by NRC in interpreting and evaluating reactor vendor EM methods and computed results. The system

M. R. Buckner; R. R. Beckmeyer; M. V. Gregory; R. L. Reed; W. G. Winn



Potential cauchy-poisson waves generated by submarine eruptions of kick 'em Jenny volcano  

Microsoft Academic Search

Kick 'em Jenny is the only known currently active submarine volcano in the Lesser Antilles. The volcano has erupted at least 10 times since first being discovered in 1939 and the summit has shoaled from a depth of ~232 m in 1962 to its present-day depth of ~150 m. Kick 'em Jenny is located in a province of explosive volcanism,

M. S. Smith; J. B. Shepherd



Efeito da vitamina C no ganho de peso e em parâmetros hematológicos de tambaqui  

Microsoft Academic Search

Resumo - O objetivo deste trabalho foi avaliar o efeito da suplementação dietária com ácido L-ascórbico (vitamina C) no ganho de peso e em parâmetros hematológicos de juvenis de tambaqui, Colossoma macropomum. Após dez semanas, em que foram alimentados com dietas contendo 0, 100 e 500 mg de ácido L-ascórbico por kg de ração, os peixes foram capturados e imediatamente

Edsandra Campos Chagas; Adalberto Luís Val




Microsoft Academic Search

RESUMO O objetivo desse trabalho foi isolar e identificar bactérias candidatas a probióticos do trato intestinal de camarões da espécie Litopenaeus vannamei, em diferentes fases de desenvolvimento. Foram utilizados camarões nas fases de recria e inicial (pós-larva) e de crescimento (juvenil), os quais eram adaptados à água doce da Fazenda BAHIA PESCA, especializada em aqüicultura, localizada no município de Santo



BSSDATA - um programa otimizado para filtragem de dados em radioastronomia solar  

Microsoft Academic Search

A partir de 1998, entrou em operação regular no INPE, em São José dos Campos, o Brazilian Solar Spectroscope (BSS). O BSS é dedicado às observações de explosões solares decimétricas com alta resolução temporal e espectral, com a principal finalidade de investigar fenômenos associados com a liberação de energia dos \\

A. R. F. Martinon; H. S. Sawant; F. C. R. Fernandes; S. Stephany; A. J. Preto; K. M. Dobrowolski




E-print Network


Paraná, Universidade Federal do


Anxiety levels in EMS providers: Effects of violence and shift schedules  

Microsoft Academic Search

We tried to measure anxiety levels in emergency medical service (EMS) providers to determine the effects of (1) having had a violent encounter during a shift and (2) different shift schedules, conducting a prospective observational study over 3 months in an urban EMS system setting. A convenience sample of 23 EMTs and 40 EMT-Ps was observed. Anxiety levels were measured

Elisabeth Fowlie Mock; Keith D Wrenn; Seth W Wright; T. Chadwick Eustis; Corey M Slovis



PERFIL DOS ACIDENTES POR LIQUIDOS AQUECIDOS EM CRIANÇAS ATENDIDAS EM CENTRO DE REFERÊNCIA DE FORTALEZA The Profile of Accidents by Hot Liquids in Children Attended at a Reference Center in Fortaleza  

Microsoft Academic Search

RESUMO As queimaduras são acidentes frequentes e representam a segunda causa de morte na infância. Este trabalho objetivou identificar o perfil dos acidentes em crianças queimadas por líquidos aquecidos. Estudo descritivo, realizado com 62 pais de crianças internadas em um Centro de Tratamento para Queimados, em Fortaleza, Ceará, no período de janeiro a junho de 2002. As variáveis estudadas foram:

Rita Neuma; Dantas Cavalcante; Érika Porto Xavier; Luiza Jane; Eyre de Souza


Cryo-EM modeling by the molecular dynamics flexible fitting method  

PubMed Central

The increasing power and popularity of cryo-electron (cryo-EM) microscopy in structural biology brought about the development of so-called hybrid methods, which permit the interpretation of cryo-EM density maps beyond their nominal resolution in terms of atomic models. The Cryo-EM Modeling Challenge 2010 is the first community effort to bring together developers of hybrid methods as well as cryo-EM experimentalists. Participating in the challenge, the molecular dynamics flexible fitting (MDFF) method was applied to a number of cryo-EM density maps. The results are described here with special emphasis on the use of symmetry-based restraints to improve the quality of atomic models derived from density maps of symmetric complexes; on a comparison of the stereochemical quality of atomic models resulting from different hybrid methods; and on application of MDFF to electron crystallography data. PMID:22696404

Chan, Kwok-Yan; Trabuco, Leonardo G.; Schreiner, Eduard; Schulten, Klaus



EMS1 gene expression in primary breast cancer: relationship to cyclin D1 and oestrogen receptor expression and patient survival  

Microsoft Academic Search

The EMS1 and CCND1 genes at chromosome 11q13 are amplified in about 15% of primary breast cancers but appear to confer different phenotypes in ER positive and ER negative tumours. Since there are no published data on EMS1 expression in large series of breast cancers we examined the relationship of EMS1 expression with EMS1 gene copy number and expression of

Rina Hui; Jonathon R Ball; R Douglas Macmillan; Frances S Kenny; Owen WJ Prall; Douglas H Campbell; Ann L Cornish; Richard A McClelland; Roger J Daly; John F Forbes; Roger W Blamey; Elizabeth A Musgrove; John FR Robertson; Robert I Nicholson; Robert L Sutherland



A Gentle Tutorial of the EM Algorithm and its Application to Parameter Estimation for Gaussian Mixture and Hidden Markov Models  

Microsoft Academic Search

We describe the maximum-likelihood parameter estimation problem and how the Expectation- Maximization (EM) algorithm can be used for its solution. We first describe the abstract form of the EM algorithm as it is often given in the literature. We then develop the EM pa- rameter estimation procedure for two applications: 1) finding the parameters of a mixture of Gaussian densities,

Jeff A. Bilmes



Efeitos da monensina sobre a fermentação e sensibilidade de bactérias ruminais de bovinos sob dietas ricas em volumoso ou concentrado  

Microsoft Academic Search

RESUMO - Objetivou-se avaliar os efeitos da monensina sobre as mudanças nos padrões de fermentação e resistência à perda do potássio intracelular das bactérias ruminais provenientes de quatro bovinos recebendo dietas ricas em volumoso ou concentrado. As bactérias obtidas por centrifugação diferencial foram resuspensas em um meio pobre em potássio, no qual foi medida a perda do p otássio intracelular,

Rogério de Paula Lana; James B. Russell




SciTech Connect

We present a spectral analysis of the Far Ultraviolet Spectroscopic Explorer (FUSE) spectra of the eclipsing double-line spectroscopic binary EM Cygni (EM Cyg), a Z Cam DN system. The FUSE spectrum, obtained in quiescence, consists of four individual exposures (orbits): two exposures, at orbital phases {phi} {approx} 0.65 and {phi} {approx} 0.90, have a lower flux; and two exposures, at orbital phases {phi} = 0.15 and 0.45, have a relatively higher flux. The change of flux level as a function of the orbital phase is consistent with the stream material (flowing over and below the disk from the hot spot region to smaller radii) partially masking the white dwarf. We carry out a spectral analysis of the FUSE data, obtained at phase 0.45 (when the flux is maximal), using synthetic spectra generated with the codes TLUSTY and SYNSPEC. Using a single white dwarf spectral component, we obtain a white dwarf temperature of 40, 000 K {+-} 1000 K, rotating at 100 km s{sup -1}. The white dwarf, or conceivably, the material overflowing the disk rim, shows suprasolar abundances of silicon, sulphur, and possibly nitrogen. Using a white dwarf+disk composite model, we obtain that the white dwarf temperature could be even as high as 50,000 K, contributing more than 90% of the FUV flux, and the disk contributing less than 10% must have a mass accretion rate reaching 10{sup -10} M{sub sun} yr{sup -1}. The single white dwarf model fits the absorption lines better than the white dwarf+disk model, but the white dwarf+disk model fits better the continuum in the shorter wavelengths. In both cases, however, we obtain that the white dwarf temperature is much higher than previously estimated. We emphasize the importance of modeling the spectra of EM Cyg around phase {phi} < 0.5, when the white dwarf and disk are facing the observer, and we suggest that the discrepancy between the present analysis and previous spectral analysis might be due to the occulting effect of the stream veiling the white dwarf and disk.

Godon, Patrick; Sion, Edward M. [Department of Astronomy and Astrophysics, Villanova University, Villanova, PA 19085 (United States); Barrett, Paul E. [United States Naval Observatory, Washington, DC 20392 (United States); Linnell, Albert P. [Department of Astronomy, University of Washington, Seattle, WA 98195 (United States)], E-mail:, E-mail:, E-mail:, E-mail:, E-mail:



The EM SSAB Annual Work Plan Process: Focusing Board Efforts and Resources - 13667  

SciTech Connect

One of the most daunting tasks for any new member of a local board of the Environmental Management Site Specific Advisory Board (EM SSAB) is to try to understand the scope of the clean-up activities going on at the site. In most cases, there are at least two or three major cleanup activities in progress as well as monitoring of past projects. When planning for future projects is added to the mix, the list of projects can be long. With the clean-up activities involving all major environmental media - air, water, soils, and groundwater, new EM SSAB members can find themselves totally overwhelmed and ineffective. Helping new members get over this initial hurdle is a major objective of EM and all local boards of the EM SSAB. Even as members start to understand the size and scope of the projects at a site, they can still be frustrated at the length of time it takes to see results and get projects completed. Many project and clean-up timelines for most of the sites go beyond 10 years, so it's not unusual for an EM SSAB member to see the completion of only 1 or 2 projects over the course of their 6-year term on the board. This paper explores the annual work planning process of the EM SSAB local boards, one tool that can be used to educate EM SSAB members into seeing the broader picture for the site. EM SSAB local work plans divide the site into projects focused on a specific environmental issue or media such as groundwater and/or waste disposal options. Projects are further broken down into smaller segments by highlighting major milestones. Using these metrics, local boards of the EM SSAB can start to quantify the effectiveness of the project in achieving the ultimate goal of site clean-up. These metrics can also trigger board advice and recommendations for EM. At the beginning of each fiscal year, the EM SSAB work plan provides a road map with quantifiable checkpoints for activities throughout the year. When the work plans are integrated with site-specific, enforceable regulatory milestones, they can provide a comprehensive work plan for not only the board, but also regulators, site contractors, and DOE. Because the work plans are reviewed and approved by DOE, they carry some weight in holding local boards of the EM SSAB accountable. This structure provides the basis for local boards to achieve their primary function, to provide DOE with information, advice, and recommendations concerning issues affecting the EM program at the site. (authors)

Young, Ralph [Paducah Citizens Advisory Board (United States)] [Paducah Citizens Advisory Board (United States)



Integrated EM & Thermal Simulations with Upgraded VORPAL Software  

SciTech Connect

Nuclear physics accelerators are powered by microwaves which must travel in waveguides between room-temperature sources and the cryogenic accelerator structures. The ohmic heat load from the microwaves is affected by the temperature-dependent surface resistance and in turn affects the cryogenic thermal conduction problem. Integrated EM & thermal analysis of this difficult non-linear problem is now possible with the VORPAL finite-difference time-domain simulation tool. We highlight thermal benchmarking work with a complex HOM feed-through geometry, done in collaboration with researchers at the Thomas Jefferson National Accelerator Laboratory, and discuss upcoming design studies with this emerging tool. This work is part of an effort to generalize the VORPAL framework to include generalized PDE capabilities, for wider multi-physics capabilities in the accelerator, vacuum electronics, plasma processing and fusion R&D fields, and we will also discuss user interface and algorithmic upgrades which facilitate this emerging multiphysics capability.

D.N. Smithe, D. Karipides, P. Stoltz, G. Cheng, H. Wang



EM Structure-Based Accelerators Working Group Summary  

NASA Astrophysics Data System (ADS)

This Working Group (WG) focused on EM Structure-Based Accelerators, which covers a broad area of mechanisms and experiments. Topics covered included dielectric wakefield accelerators (DWA), photonic bandgap accelerators (PBGA), inverse free electron lasers (IFEL), vacuum laser accelerators (VLA), other novel schemes, and supporting analysis and modeling. In addition, this WG was tasked at the Workshop with developing conceptual (strawman) designs for a 1-GeV accelerator system based upon any of the experimentally-proven approaches covered in this WG. Two strawmen designs were developed based upon IFELs and DWAs. The presentations given and strawmen designs indicate great progress has been made in many areas. Proof-of-principle experiments will occur shortly in PBGA and VLA. Other well-proven devices, such as IFELs, are becoming accepted as "workhorse" providers of microbunches.

Kimura, W. D.; Lidia, S. M.



EM-based measurement fusion for HRR radar centroid processing  

NASA Astrophysics Data System (ADS)

This paper develops a new algorithm for high range resolution (HRR) radar centroid processing for scenarios where there are closely spaced objects. For range distributed targets with multiple discrete scatterers, HRR radars will receive detections across multiple range bins. When the resolution is very high, and the target has significant extent, then it is likely that the detections will not occur in adjacent bins. For target tracking purposes, the multiple detections must be grouped and fused to create a single object report and a range centroid estimate is computed since the detections are range distributed. With discrete scatterer separated by multiple range bins, then when closely spaced objects are present there is uncertainty about which detections should be grouped together for fusion. This paper applies the EM algorithm to form a recursive measurement fusion algorithm that segments the data into object clusters while simultaneously forming a range centroid estimate with refined bearing and elevation estimates.

Slocumb, Benjamin J.; Blair, W. Dale



SEI: Junior E&M I Course Materials - Homework  

NSDL National Science Digital Library

This homework question collection was constructed over the course of four semesters of a transformed junior-level Electricity and Magnetism course on electro- and magneto-statics. Many questions are related to textbook problems, but with added elements of explanation, sense-making, estimation or approximation, real-world connections, and multiple-representations. Not all these homework questions were used in the course design project. Some problems used include detailed instructor notes, including statistics on student performance on each homework problem assigned. The homework solutions are only available to instructors by writing the authors, This material was developed as part of a education research-based course transformation for junior level E&M. All of the resources developed for this course are available, sorted by individual topic and type, at

Pollock, Steven J.; Chasteen, Stephanie V.



SEI: Junior E&M I Course Materials - Tutorials  

NSDL National Science Digital Library

This collection of tutorials and tutorial pre-tests was constructed for a transformed junior-level Electricity and Magnetism course. These tutorials are weekly student sessions, modeled after research-validated curricula developed at the University of Washington. Using these materials in study/recitation sections, students work in small groups with the instructor as a learning coach. The materials are designed to target known student difficulties, to elicit and develop conceptual understanding and math/physics connections. They also help faculty listen to student reasoning, get a clearer sense of student ideas, and determine where they are struggling. This material was developed as part of a education research-based course transformation for junior level E&M. All of the resources developed for this course are available, sorted by individual topic and type, at

Pollock, Steven J.; Chasteen, Stephanie V.; Kinney, Edward; Dubson, Michael



EM modeling of RF drive in DTL tank 4  

SciTech Connect

A 3-D MicroWave Studio model for the RF drive in the LANSCE DTL tank 4 has been built. Both eigensolver and time-domain modeling are used to evaluate maximal fields in the drive module and RF coupling. The LANSCE DTL tank 4 has recently been experiencing RF problems, which may or may not be related to its replaced RF coupler. This situation stimulated a request by Dan Rees to provide EM modeling of the RF drive in the DTL tank 4 (T4). Jim O'Hara provided a CAD model that was imported into the CST Microwave Studio (MWS) and after some modifications became a part of a simplified MWS model of the T4 RF drive. This technical note describes the model and presents simulation results.

Kurennoy, Sergey S. [Los Alamos National Laboratory



Speech articulator measurements using low power EM-wave sensors  

SciTech Connect

Very low power electromagnetic (EM) wave sensors are being used to measure speech articulator motions as speech is produced. Glottal tissue oscillations, jaw, tongue, soft palate, and other organs have been measured. Previously, microwave imaging (e.g., using radar sensors) appears not to have been considered for such monitoring. Glottal tissue movements detected by radar sensors correlate well with those obtained by established laboratory techniques, and have been used to estimate a voiced excitation function for speech processing applications. The noninvasive access, coupled with the small size, low power, and high resolution of these new sensors, permit promising research and development applications in speech production, communication disorders, speech recognition and related topics. {copyright} {ital 1998 Acoustical Society of America.}

Holzrichter, J.F.; Burnett, G.C.; Ng, L.C. [Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, California 94551 (United States)] [Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, California 94551 (United States); Lea, W.A. [Speech Science Institute, P.O. Box 240428, Apple Valley, Minnesota 55124 (United States)] [Speech Science Institute, P.O. Box 240428, Apple Valley, Minnesota 55124 (United States)



EM Properties of Magnetic Minerals at RADAR Frequencies  

NASA Technical Reports Server (NTRS)

Previous missions to Mars have revealed that Mars surface is magnetic at DC frequency. Does this highly magnetic surface layer attenuate RADAR energy as it does in certain locations on Earth? It has been suggested that the active magnetic mineral on Mars is titanomaghemite and/or titanomagnetite. When titanium is incorporated into a maghemite or magnetite crystal, the Curie temperature can be significantly reduced. Mars has a wide range of daily temperature fluctuations (303K - 143K), which could allow for daily passes through the Curie temperature. Hence, the global dust layer on Mars could experience widely varying magnetic properties as a function of temperature, more specifically being ferromagnetic at night and paramagnetic during the day. Measurements of EM properties of magnetic minerals were made versus frequency and temperature (300K- 180K). Magnetic minerals and Martian analog samples were gathered from a number of different locations on Earth.

Stillman, D. E.; Olhoeft, G. R.



EM Structure-Based Accelerators Working Group Summary  

SciTech Connect

This Working Group (WG) focused on EM Structure-Based Accelerators, which covers a broad area of mechanisms and experiments. Topics covered included dielectric wakefield accelerators (DWA), photonic bandgap accelerators (PBGA), inverse free electron lasers (IFEL), vacuum laser accelerators (VLA), other novel schemes, and supporting analysis and modeling. In addition, this WG was tasked at the Workshop with developing conceptual (strawman) designs for a 1-GeV accelerator system based upon any of the experimentally-proven approaches covered in this WG. Two strawmen designs were developed based upon IFELs and DWAs. The presentations given and strawmen designs indicate great progress has been made in many areas. Proof-of-principle experiments will occur shortly in PBGA and VLA. Other well-proven devices, such as IFELs, are becoming accepted as 'workhorse' providers of microbunches.

Kimura, W.D. [STI Optronics, Inc., 2755 Northup Way, Bellevue, WA 98004 (United States); Lidia, S.M. [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States)



QCD effective potential with strong U(1)em magnetic fields  

NASA Astrophysics Data System (ADS)

We derive the analytic expression for the one-loop SU(Nc) QCD effective potential including Nf flavor quarks which nonlinearly interact with the chromomagnetic background field and the external U(1)em magnetic field. After the renormalization of couplings and fields, we obtain the correct one-loop ? functions of both QCD and QED, and the resulting effective potential satisfies the renormalization group equation. We investigate the effect of the magnetic field on the QCD vacuum by using the effective potential, in particular for the color SU(3) case with the three flavors (u ,d,s). Our result shows that the chromomagnetic field prefers to be parallel to the external magnetic field. Furthermore, quark loop contributions to the effective potential with the magnetic field enhance gluonic contributions, and then the chromomagnetic condensate increases with an increasing magnetic field. This result supports the recent observed gluonic magnetic catalysis at zero-temperature in lattice QCD.

Ozaki, Sho



Benchmarking a derivative-free minimax optimizer for EM design  

NASA Astrophysics Data System (ADS)

The paper presents a model-based derivative-free minimax optimizer and a benchmarking methodology. The optimizer is dedicated to such simulation-based design scenarios, when a single simulation is time-consuming and not very accurate, and so when fast improvement of design is expected rather then high accuracy optimization. A benchmarking methodology is formulated to compare efficiency of optimizers in such scenarios. A set of electromagnetic (EM) designs, for which a design simulation involves solution of very large partial differential equations, is used to exemplify the methodology. Presented results demonstrate how accuracy requirements and computational budget change ranking of optimizers. The proposed optimizer is shown to provide competetively rapid and reliable initial design improvement for modest 5-10% tolerance, but for higher accuracy demands and larger computational budget other solvers become more competitive.

Opalski, Leszek J.


TrakEM2 software for neural circuit reconstruction.  


A key challenge in neuroscience is the expeditious reconstruction of neuronal circuits. For model systems such as Drosophila and C. elegans, the limiting step is no longer the acquisition of imagery but the extraction of the circuit from images. For this purpose, we designed a software application, TrakEM2, that addresses the systematic reconstruction of neuronal circuits from large electron microscopical and optical image volumes. We address the challenges of image volume composition from individual, deformed images; of the reconstruction of neuronal arbors and annotation of synapses with fast manual and semi-automatic methods; and the management of large collections of both images and annotations. The output is a neural circuit of 3d arbors and synapses, encoded in NeuroML and other formats, ready for analysis. PMID:22723842

Cardona, Albert; Saalfeld, Stephan; Schindelin, Johannes; Arganda-Carreras, Ignacio; Preibisch, Stephan; Longair, Mark; Tomancak, Pavel; Hartenstein, Volker; Douglas, Rodney J



DOE-EM privatization and the 2006 Plan: Principles for procurement policies and risk management  

SciTech Connect

The Department of Energy`s Office of Environmental Remediation and Waste Management (EM) has recently set in place programs to restructure the strategic planning mechanism that will drive its clean-up schedule, The 2006 Plan, and to create a new set of business relationships with private contractors that will reduce costs--privatization. Taken together, the 2006 Plan and privatization will challenge EM to create new business practices to recast its risk management policies to support these initiatives while ensuring that its responsibilities toward the environment, human health, and worker safety (ES and H) are maintained. This paper argues that the 2006 Plan has transformed EM`s traditional, bottoms-up approach based on technical dictates to a top-down approach based on management goals--a transformation from an engineering problem to an economic problem. The 2006 Plan evolved from EM`s Ten-Year Plan, and seeks to convert the largely open-ended planning approach previously undertaken by EM to a plan bounded by time and dollars. The plan emphasizes making tradeoffs and choosing activities that deliver the most clean-up for the dollar. It also recognizes that each major player--stakeholders, DOE, OMB and Congress--has distinct interests that must be resolved if the process is to succeed. This, in turn, has created the need for a corresponding transformation in risk management practices from compliance-driven to benefit/cost-driven.

Bjornstad, D.J.; Jones, D.W.; Duemmer, C.L.



Linear array implementation of the EM algorithm for PET image reconstruction  

SciTech Connect

The PET image reconstruction based on the EM algorithm has several attractive advantages over the conventional convolution back projection algorithms. However, the PET image reconstruction based on the EM algorithm is computationally burdensome for today`s single processor systems. In addition, a large memory is required for the storage of the image, projection data, and the probability matrix. Since the computations are easily divided into tasks executable in parallel, multiprocessor configurations are the ideal choice for fast execution of the EM algorithms. In tis study, the authors attempt to overcome these two problems by parallelizing the EM algorithm on a multiprocessor systems. The parallel EM algorithm on a linear array topology using the commercially available fast floating point digital signal processor (DSP) chips as the processing elements (PE`s) has been implemented. The performance of the EM algorithm on a 386/387 machine, IBM 6000 RISC workstation, and on the linear array system is discussed and compared. The results show that the computational speed performance of a linear array using 8 DSP chips as PE`s executing the EM image reconstruction algorithm is about 15.5 times better than that of the IBM 6000 RISC workstation. The novelty of the scheme is its simplicity. The linear array topology is expandable with a larger number of PE`s. The architecture is not dependant on the DSP chip chosen, and the substitution of the latest DSP chip is straightforward and could yield better speed performance.

Rajan, K.; Patnaik, L.M.; Ramakrishna, J. [Indian Institute of Science, Bangalore (India)] [Indian Institute of Science, Bangalore (India)



Annual Report Center for Latin American Studies  

E-print Network

-hand accounts of events of interest concerning Latin America provided as blogs by our faculty, students and that centered around the exhibit Queloides: Race and Racism in Cuban Contemporary Art (co-curated by CLAS of Latin American Studies (MACLAS) Conference on Globalization and Well-Being in Latin America. Through

Machery, Edouard


Queda dos homic?dios em S?o Paulo, Brasil: uma an?lise descritiva  

PubMed Central

Objetivo Descrever a evolução da mortalidade por homicídios no Município de São Paulo segundo tipo de arma, sexo, raça ou cor, idade e áreas de exclusão/inclusão social entre 1996 e 2008. Métodos Estudo ecológico de série temporal. Os dados sobre óbitos ocorridos no Município foram coletados da base de dados do Programa de Aprimoramento das Informações sobre Mortalidade, seguindo a Classificação Internacional de Doenças, Décima Revisão (CID-10). Foram calculadas as taxas de mortalidade por homicídio (TMH) para a população total, por sexo, raça ou cor, faixa etária, tipo de arma e área de exclusão/inclusão social. As TMH foram padronizadas por idade pelo método direto. Foram calculados os percentuais de variação no período estudado. Para as áreas de exclusão/inclusão social foram calculados os riscos relativos de morte por homicídio. Resultados As TMH apresentaram queda de 73,7% entre 2001 e 2008. Foi observada redução da TMH em todos os grupos analisados, mais pronunciada em homens (?74,5%), jovens de 15 a 24 anos (?78,0%) e moradores de áreas de exclusão social extrema (?79,3%). A redução ocorreu, sobretudo, nos homicídios cometidos com armas de fogo (?74,1%). O risco relativo de morte por homicídio nas áreas de exclusão extrema (tendo como referência áreas com algum grau de exclusão social) foi de 2,77 em 1996, 3,9 em 2001 e 2,13 em 2008. Nas áreas de alta exclusão social, o risco relativo foi de 2,07 em 1996 e 1,96 em 2008. Conclusões Para compreender a redução dos homicídios no Município, é importante considerar macrodeterminantes que atingem todo o Município e todos os subgrupos populacionais e microdeterminantes que atuam localmente, influenciando de forma diferenciada os homicídios com armas de fogo e os homicídios na população jovem, no sexo masculino e em residentes em áreas de alta exclusão social. PMID:21390415

Peres, Maria Fernanda Tourinho; Vicentin, Diego; Nery, Marcelo Batista; de Lima, Renato Sergio; de Souza, Edinilsa Ramos; Cerda, Magdalena; Cardia, Nancy; Adorno, e Sergio



Ondas de choque em jatos de quasares e objetos BL Lacertae  

NASA Astrophysics Data System (ADS)

Este trabalho é parte de um projeto que vem sendo realizado há dois anos no CRAAM, cujos objetivos principais são analisar e aplicar um modelo generalizado de ondas de choque em jatos relativísticos de plasma, presentes em quasares e objetos BL Lacertae, para explicar a variabilidade observada nestes objetos. O método consiste em uma decomposição de curvas de luz em séries de explosões similares, em várias freqüências, baseando-se em uma evolução espectro-temporal média das explosões. A partir da evolução média, um ajuste de cada explosão é feito com base em equações empíricas, modificando-se apenas parâmetros específicos de cada explosão. Inicialmente o modelo foi aplicado ajustando-se as curvas de luz a explosões delineadas por uma evolução do choque em três estágios, segundo a predominância do processo de emissão: síncrotron, Compton e adiabático. Entretanto, nesta nova fase de projeto, visando uma parametrização mais concisa, uma otimização do algoritmo de ajuste e uma convergência mais rápida, a formulação para cada evento foi assumida com uma evolução em apenas dois estágios: subida e descida. Isto possibilitou uma ótima delineação das curvas de luz das fontes OV236, OJ287, 3C273 e BL Lac, entre 1980 e 2000, nas freqüências 4.8, 8.0, 14.5 e 22 GHz, utilizando-se dados do Observatório da Universidade de Michigan, do Observatório do Itapetinga (Atibaia SP) e do Observatório Metsähovi. Como conclusões importantes, verificou-se que: os parâmetros ajustados descrevem o comportamento do jato; os valores do índice que descreve a expansão do jato sugerem que o mesmo se expande de uma forma não-cônica; o campo magnético é turbulento atrás da frente de choque; e as peculiaridades das explosões são devidas à influência de grandezas tais como o coeficiente da distribuição espectral de energia dos elétrons, a intensidade de campo magnético e o fator de feixe Doppler, no início do choque.

Melo, F. E.; Botti, L. C. L.



EM Wake-Sleep  

E-print Network

­EM Wake-Sleep ­ 21 2-1 1 (Latent Variable) 2 2.1 -5 -2.5 0 2.5 5 x+1), p(x; )) t+1 6 #12;3.3 Wake-Sleep EM G. Hinton EM Wake-Sleep [6] Helmholtz Helmholtz Helmholtz Helmholtz 6 M D q(y|x; ) p(x, y; ) 2 Wake-Sleep t+1 D M KL(q ,p )KL(p ,q ) t+1 t () ()() () t 7: Wake

Ikeda, Shiro


User's guide for the PWR LOCA analysis capability of the WRAP-EM system  

SciTech Connect

The Water Reactor Analysis Package (WRAP) has been expanded to provide the capability to analyze loss-of-coolant accidents (LOCAs) in both pressurized water reactors (PWRs) and boiling water reactors (BWRs) by using evaluation models (EMs). The input specifications for modules in the WRAP-EM system are presented in this document along with the JOSHUA input templates. This document, along with the WRAP user's guide, provides a step-by-step procedure for setting up a PWR data base for the WRAP-EM system. 12 refs.

Beranek, F; Gregory, M V



EMS Provider Assessment of Vehicle Damage Compared to a Professional Crash Reconstructionist  

PubMed Central

Objective To determine the accuracy of EMS provider assessments of motor vehicle damage, when compared to measurements made by a professional crash reconstructionist. Methods EMS providers caring for adult patients injured during a motor vehicle crash and transported to the regional trauma center in a midsized community were interviewed upon ED arrival. The interview collected provider estimates of crash mechanism of injury. For crashes that met a preset severity threshold, the vehicle’s owner was asked to consent to having a crash reconstructionist assess their vehicle. The assessment included measuring intrusion and external auto deformity. Vehicle damage was used to calculate change in velocity. Paired t-test and correlation were used to compare EMS estimates and investigator derived values. Results 91 vehicles were enrolled; of these 58 were inspected and 33 were excluded because the vehicle was not accessible. 6 vehicles had multiple patients. Therefore, a total of 68 EMS estimates were compared to the inspection findings. Patients were 46% male, 28% admitted to hospital, and 1% died. Mean EMS estimated deformity was 18” and mean measured was 14”. Mean EMS estimated intrusion was 5” and mean measured was 4”. EMS providers and the reconstructionist had 67% agreement for determination of external auto deformity (kappa 0.26), and 88% agreement for determination of intrusion (kappa 0.27) when the 1999 Field Triage Decision Scheme Criteria were applied. Mean EMS estimated speed prior to the crash was 48 mph±13 and mean reconstructionist estimated change in velocity was 18 mph±12 (correlation -0.45). EMS determined that 19 vehicles had rolled over while the investigator identified 18 (kappa 0.96). In 55 cases EMS and the investigator agreed on seatbelt use, for the remaining 13 cases there was disagreement (5) or the investigator was unable to make a determination (8) (kappa 0.40). Conclusions This study found that EMS providers are good at estimating rollover. Vehicle intrusion, deformity, and seatbelt use appear to be more difficult to estimate with only fair agreement with the crash reconstructionist. As expected, the EMS provider estimated speed prior to the crash does not appear to be a reasonable proxy for change in velocity. PMID:21815732

Lerner, E. Brooke; Cushman, Jeremy T.; Blatt, Alan; Lawrence, Richard; Shah, Manish N.; Swor, Robert; Brasel, Karen; Jurkovich, Gregory J.



Investigating the source of contaminated plumes downstream of the Alborz Sharghi coal washing plant using EM34 conductivity data, VLF-EM and DC-resistivity geophysical methods  

NASA Astrophysics Data System (ADS)

Coal washing factories may create serious environmental problems due to pyrite oxidation and acid mine drainage generation from coal waste piles on nearby land. Infiltration of pyrite oxidation products through the porous materials of the coal waste pile by rainwater cause changes in the conductivity of underground materials and groundwater downstream of the pile. Electromagnetic and electrical methods are effective for investigation and monitoring of the contaminated plumes caused by coal waste piles and tailings impoundments. In order to investigate the environmental impact from a coal waste pile at the Alborz Sharghi coal washing plant, an EM34 ground conductivity meter was used on seven parallel lines in an E-W direction, downstream of the waste pile. Two-dimensional resistivity models obtained by the inversion of EM34 conductivity data identified conductive leachate plumes. In addition, quasi-3D inversion of EM34 data has confirmed the decreasing resistivity at depth due to the contaminated plumes. Comparison between EM34, VLF and DC-resistivity datasets, which were acquired for similar survey lines, agree well in identifying changes in the resistivity trend. The EM34 and DC-resistivity sections have greater similarity and better smoothness rather than those of the VLF model. Two-dimensional inversion models of these methods have shown some contaminated plumes with low resistivity.

Shiraz, Farzin Amirkhani; Ardejani, Faramarz Doulati; Moradzadeh, Ali; Arab-Amiri, Ali Reza



Serodiagnosis of alveolar echinococcosis: detection of antibody against EM18 in patients and rodents.  


An international collaborative study on echinococcosis has been carried out for the establishment of a simple means for differential serodiagnosis of alveolar echinococcosis (AE) from other parasitic diseases including cystic echinococcosis (CE). The main candidate epitope is Em18 (previously undescribed epitope of a low molecular weight protein of 18.5 kDa). Evaluation of the usefulness of Em18 is introduced in this review paper. Serum samples showing antibody response against Em18 are exclusively from AE. The predominant IgG subclass recognizing Em18 is IgG4 or IgG1 or IgG4 + IgG1 but never IgG2. There are good correlations between (1) the antibody response against Em18 and the presence of active lesions and (2) the antibody response against Em18 and the Em2-ELISA values. Em18 is, therefore, expected to be reasonably reliable and useful for differentiation of active AE from inactive AE. A new ELISA system using a partially purified Em18 enriched fraction (PP-Em 18/16-ELISA) has been evaluated for serodiagnosis of AE compared with Em2plus-ELISA. A total of 194 serum samples were examined: 127 sera from AE (79) and CE (48) in China where both AE and CE are endemic, 21 sera from CE in Australia where CE only exists, 28 sera from cysticercosis (21), paragonimiasis (5) or sparganasis (2) in Korea where no indigenous AE nor CE exists and 11 normal sera. Antibody levels by PP-Em18/16-ELISA were much higher in AE than in CE and it was also true for commercially available Em2plus-ELISA. Some of CE from China showed exceptionally higher levels of antibody in comparison with those of CE from Australia. It is suggested that these strongly positive cases of CE from China may have been exposed to both species of Echinococcus. Although most of sera from paragonimiasis showed high antibody levels by Emplus-ELISA, they were negative by PP-Em18/16-ELISA. Therefore, PP-Em18/16-ELISA is expected to be more reliable for differentiation of AE from CE and others especially in Asian countries where paragonimiasis is still not rare. Antibody responses in rodents naturally infected with E. multilocularis: Serum samples from the wild vole, Clethrionomys rufocanus bedfordiae, infected with E. multilocularis showed similar antibody responses as in AE patients, whereas those from Norway rats, Rattus norvegicus, showed almost none. The latter rodents were simultaneously infected with Taenia taeniaeformis but showed no antibody response against T. taeniaeformis either. Therefore, we speculate that Norway rats may only be infected with E. multilocularis under some immunosuppressed conditions or genetic unresponsiveness. It is stressed that Em18 is highly specific to E. multilocularis, and antibody response against Em18 is reasonably reliable for differentiation of AE from other helminthic infections by Western blot and ELISA in humans and may be useful for detection of domestic animals contaminated with E. multilocularis in the endemic area. PMID:9656361

Akira, I



MINUTA DE PARECER DA COMISSO INTERNA DE SUPERVISO O Pleno da Comisso Interna de Superviso dos Cargos Tcnico-Administrativos em Educao da  

E-print Network

". Neste Of�cio a pr�pria reitora em exerc�cio reconhece que, ap�s a avalia��o participativa em todos os foi firmado em documento oficial pela pr�pria reitora em exerc�cio, deveria ser aberto processo

Floeter, Sergio Ricardo


Simulating Suspended Silt Concentrations in the Ems Estuary, The Netherlands  

NASA Astrophysics Data System (ADS)

1 Introduction The Ems Estuary is situated in the North-east Netherlands on the border with Germany. Its area, including the tidal river and excluding the outer delta, is ± 500 km2. The area of the outer delta is ± 100 km2. The length of the estuary from the inlet to the town of Leer in Germany is approximately 75 km. The mean tidal range varies over years (de Jonge, 1992), but is approximately 2.3 m near the island of Borkum (tidal inlet) and approximately 3.2 m near the town of Emden in Germany. The estuary receives water from the rain-fed River Ems (approximately 115 m3/s on average). A second much smaller freshwater input emanates from the small canalized river Westerwoldsche Aa (12.5 m3/s on average). These discharges vary strongly within and between years. The result of the interaction between freshwater discharge and seawater brought in by the tide is a salinity gradient, the length and position of which is strongly dependent on the water discharge by the rivers. The present morphology of the estuary is the result of natural processes such as tidal currents, wind and wave driven currents and river discharge, resulting in sediment trans-port and sedimentation and erosion patterns. These natural processes are affected by human interferences like maintenance dredging of the navigation channels, land reclamation, building of dikes, etc. The greatest changes in the last 50 years in the physical functioning of the Ems estuary have been the increased sea level and tidal range, the increased amplitude and frequency of storm surge, and greatly increased turbidity and sediment concentrations (particularly near the estuarine turbidity maximum). Much of the changes can be traced directly or indirectly to anthropogenic influence. 2 Aim and approach We studied the hydrodynamics and morphodynamics of the Ems estuary. One of the aims was to gain more insight in the behaviour of the suspended silt concentrations in the estuary and the anthropogenic influence thereon. We applied a beta release of the state-of-the-art Delft3D numerical model for this purpose. The model includes a new sediment transport module published by Van Rijn (2007, 2007a). The vertical distribution of the suspended sediment concentration in the transport module depends on the effective settling velocity of the sediment, the bed shear velocity and the turbulence. The silt transport is simulated every time step together with the flow (online), which means that the impact of the calculated concentration is accounted for in the hydrodynamics. Major challenge was to accurately simulate the relatively high suspended silt concentrations observed near the estuarine turbidity maximum. 3 Results The paper will compare observed and predicted water levels, salinity distributions and suspended silt concentrations. Figure 1 shows an example of predicted depth-averaged suspended silt concentrations during spring high tide without waves. Under these conditions the depth-averaged concentrations decrease from about 2 kg/m3 in the Unterems (upstream of Emden) to almost zero seaward of Borkum. PIC Figure 1: Figure 2 Observed and predicted salinities in the upper part of the water column along the estuary The presence of waves will increase the concentrations on the shoals but have a limited effect on the concentrations in the channels. Figure 2 presents observed and predicted salinities along the estuary. The model results encouragingly agree with the observations. PIC 4 References De Jonge, V.N., 1992. Tidal flow and residual flow in the Ems estuary. Estuarine, Coastal and Shelf Science, 34: 1-22. Van Rijn, L.C., 2007. Unified View of Sediment Transport by Currents and Waves. I: Initiation of Motion, Bed Roughness, and Bed-Load Transport. Journal of Hydraulic Engineering, 133(6): 649-667. Van Rijn, L.C., 2007a. Unified View of Sediment Transport by Currents and Waves. II: Suspended Transport. Journal of Hydraulic Engineering, 133(6): 668-689.

Grasmeijer, B. T.



EM anomalies before the Kozani earthquake: A study of their behavior through laboratory experiments  

NASA Astrophysics Data System (ADS)

Strong electromagnetic (EM) anomalies have been detected, from MHz to kHz, prior to the three destructive earthquakes occurred during 1995-1999 in Greece. The observed sequence of EM anomalies before the Kozani-Grevena earthquake (K-G) of Ms = 6.6 on May 13, 1995 showed some important characteristics: (i) an increasing electromagnetic emission rate; (ii) an emergence of lower kHz frequencies with large amplitudes at the tail of the MHz electromagnetic anomaly; (iii) an electromagnetic quiescence approximately a few hours before the earthquake and (iv) a total absence of EM anomalies during the aftershock period. All these features are compatible with those reported by other authors. This sequence of the field observed EM signals revealed, in terms of emission pattern, similarities to the laboratory acoustic (AE) emissions during different stages of failure preparation process in rocks.

Eftaxias, K.; Kapiris, P.; Dologlou, E.; Kopanas, J.; Bogris, N.; Antonopoulos, G.; Peratzakis, A.; Hadjicontis, V.



Remembering A.S. Kronrod \\Lambda E.M. Landis and I.M. Yaglom  

E-print Network

Remembering A.S. Kronrod \\Lambda E.M. Landis and I.M. Yaglom Translation by Viola Brudno Edited --- even by his appearance --- he was tall and had a beautiful sonorous voice. While still a freshman, A

Laurie, Dirk


V.S. Ramachandran and E.M. Hubbard The Phenomenology of Synaesthesia  

E-print Network

V.S. Ramachandran and E.M. Hubbard The Phenomenology of Synaesthesia Abstract: This article the phenomenology of synaesthesia in greater detail, raise several new questions that have emerged from recent

Ramachandran, Vilayanur S.


Histórico demográfico e filogeografia em populações brasileiras de Ardea alba egretta.  

E-print Network

??Foram estudadas populações de Ardea alba egretta (garça-branca-grande) da família Ardeidae (Aves), amostradas em quatro regiões brasileiras, com latitudes diferentes (Rio Grande do Sul, Pantanal,… (more)

Thaís Camilo Corrêa



Degradação de paracetamol empregando tecnologia oxidativa avançada baseada em fotocatálise heterogênea usando irradiação artificial e solar.  

E-print Network

??No presente trabalho avaliou-se a oxidação e a mineralização do paracetamol, baseada em processos oxidativos avançados, via fotocatálise heterogênea. Estudou-se a ação de dois fotocatalisadores:… (more)

Marcela Dias França



Mars' Magnetic Atmosphere: Ionospheric Currents, Lightning (or not), E&M; Subsurface Sounding, and Future Missions  

NASA Astrophysics Data System (ADS)

Mars' ionosphere has no obvious magnetic signs of large-scale, dust-produced lightning. However, there are numerous interesting ionospheric currents (some associated with crustal magnetic fields) which would allow for E&M; subsurface sounding.

Espley, J. R.; Connerney, J. E. P.



EM2006K-33 revised Identification of forces shaping the commensal Escherichia coli  

E-print Network

1 EM2006K-33 revised Identification of forces shaping the commensal Escherichia coli genetic title: Commensal Escherichia coli ecological structure Key words: Escherichia coli, commensal, animal forces shaping the Escherichia coli intraspecies ecological structure, we have characterized in terms


Tide-driven fluid mud transport in the Ems estuary  

NASA Astrophysics Data System (ADS)

The Ems estuary, located at the border between The Netherlands and Germany, experienced a significant change of the hydrodynamic regime during the past decades, as a result of extensive river engineering. With the net sediment transport now being flood-oriented, suspended sediment concentrations have increased dramatically, inducing siltation and formation of fluid mud layers, which, in turn, influence hydraulic flow properties, such as turbulence and the apparent bed roughness. Here, the process-based understanding of fluid mud is essential to model and predict mud accumulation, not only regarding the anthropogenic impact, but also in view of the expected changes of environmental boundary conditions, i.e., sea level rise. In the recent past, substantial progress has been made concerning the understanding of estuarine circulation and influence of tidal asymmetry on upstream sediment accumulation. While associated sediment transport formulations have been implemented in the framework of numerical modelling systems, in-situ data of fluid mud are scarce. This study presents results on tide-driven fluid mud dynamics, measured during four tidal cycles aside the navigation channel in the Ems estuary. Lutoclines, i.e., strong vertical density gradients, were detected by sediment echo sounder (SES). Acoustic Doppler current profiles (ADCP) of different acoustic frequencies were used to determine hydrodynamic parameters and the vertical distribution of suspended sediment concentrations in the upper part of the water column. These continuous profiling measurements were complemented by CTD, ADV, and OBS casts. SES and ADCP profiles show cycles of fluid mud entrainment during accelerating flow, and subsequent settling, and the reformation of a lutocline during decelerating flow and slack water. Significant differences are revealed between flood and ebb phase. Highest entrainment rates are measured at the beginning of the flood phase, associated with strong current shear and rapid vertical mixing, inducing the highest instantaneous suspended sediment flux measured during the tidal cycle. During decelerating flood currents a lutocline is again established at a certain distance above the consolidated river bed. During slack water after the flood phase the concentration gradient increases and the thickness of the fluid mud layer below is constant, also during a significant part of the ebb phase. As water depth decreases during ebb, entrainment occurs only at the upper part of the fluid mud layer. The suspended sediment flux is low compared to the flood phase. These observations are further elaborated using turbulence parameters obtained from ADV and ADCP, explaining the difference between ebb and flood concerning the vertical location of the maximum concentration gradient. This study is funded through DFG-Research Center / Excellence Cluster "The Ocean in the Earth System". The Senckenberg Institute and the Federal Waterways Engineering and Research Institute are acknowledged for technical support.

Becker, Marius; Maushake, Christian; Winter, Christian



Using EM to Obtain Asymptotic Variance-Covariance Matrices: The SEM Algorithm  

Microsoft Academic Search

The expectation maximization (EM) algorithm is a popular, and often remarkably simple, method for maximum likelihood estimation in incomplete-data problems. One criticism of EM in practice is that asymptotic variance–covariance matrices for parameters (e.g., standard errors) are not automatic byproducts, as they are when using some other methods, such as Newton–Raphson. In this article we define and illustrate a procedure

Xiao-Li Meng; Donald B. Rubin



Application of Fuzzy Logic to EMS-type Magnetically Levitated Railway Vehicle  

Microsoft Academic Search

A type of the magnetically levitated railway system with the electro-magnetic suspension system (EMS), which is named HSST system, will be put into revenue service as an urban transport in Nagoya, Japan at the beginning of April 2005. To extend its operational velocity higher than 200km\\/h for applications in other cities, the design of its EMS system is reexamined for

Shinichi Kusagawa; Jumpei Baba; Katsuhiko Shutoh; Eisuke Masada



0.5setgray00.5setgray1 Determinao de coeficientes em equaes  

E-print Network

; · Resson^ancia Magn´etica ­ MRI. ­ p. 12/6 #12;Técnicas para Geração de Imagens em Medicina Nuclear · Single Photon Emission Tomography ­ SPECT, · Positron Emission Tomograpy ­ PET; · Medicina Nuclear´ogicas, microscopia, entre outros. ­ p. 10/6 #12;T´ecnicas para Gerac¸~ao de Imagens em Medicina ­ p. 11/6 #12

Cipolatti, Rolci


Pre-flight risk assessment in emergency medical service (EMS) helicopters  

NASA Technical Reports Server (NTRS)

A preflight risk assessment system (SAFE) was developed at NASA-Ames Research Center for civil EMS operations to assist pilots in making a decision objectively to accept or decline a mission. The ability of the SAFE system to predict risk profiles was examined at an EMS operator. Results of this field study showed that the usefulness of SAFE was largely dependent on the type of mission flown.

Shively, Robert J.



Self-assembled monolayers improve protein distribution on holey carbon cryo-EM supports  

PubMed Central

Poor partitioning of macromolecules into the holes of holey carbon support grids frequently limits structural determination by single particle cryo-electron microscopy (cryo-EM). Here, we present a method to deposit, on gold-coated carbon grids, a self-assembled monolayer whose surface properties can be controlled by chemical modification. We demonstrate the utility of this approach to drive partitioning of ionotropic glutamate receptors into the holes, thereby enabling 3D structural analysis using cryo-EM methods. PMID:25403871

Meyerson, Joel R.; Rao, Prashant; Kumar, Janesh; Chittori, Sagar; Banerjee, Soojay; Pierson, Jason; Mayer, Mark L.; Subramaniam, Sriram




E-print Network

ANÁLISE DE SUPERFÍCIES BOMBARDEADAS POR FEIXES DE EL�TRONS AUTOFOCALIZADOS EM UM SISTEMA DE PLAMA um considerável aumento de dureza e redução de desgaste no material sem afetar suas propriedades feixes de elétrons deslocando-se em um tubo contento um gás de baixa densidade. A colisão de elétrons com


(continuao das responsabilidades) um estudo em que voc talvez se inscreva, possvel  

E-print Network

(continuação das responsabilidades) um estudo em que você talvez se inscreva, é possível também que tenha que assumir um conjunto geral de responsabilidades pertinentes a todos os participantes da com informação. Caso tenha alguma dúvida a respeito de seus direitos como voluntário em um estudo de

Oliver, Douglas L.


Helicopter-borne measurements of sea ice thickness, using a small and lightweight, digital EM system  

Microsoft Academic Search

Sea ice is an important climate variable and is also an obstacle for marine operations in polar regions. We have developed a small and lightweight, digitally operated frequency-domain electromagnetic-induction (EM) system, a so-called EM bird, dedicated for measurements of sea ice thickness. It is 3.5 m long and weighs only 105 kg, and can therefore easily be shipped to remote places and

Christian Haas; John Lobach; Stefan Hendricks; Lasse Rabenstein; Andreas Pfaffling



Colquio em homenagem ao centenrio da morte de Henri Poincar Rio de Janeiro  

E-print Network

Colóquio em homenagem ao centenário da morte de Henri Poincaré Rio de Janeiro 27 a 30 de novembro Henri Poincaré (Université Nancy 2) Em 2012, ocorrerá o primeiro centenário da morte do matemático morte de Poincaré, além de ser uma merecida homenagem a um cientista-filósofo, cujas idéias ainda hoje

Solodov, Mikhail V.


The use of EM-CCDs on high resolution soft x-ray spectrometers  

Microsoft Academic Search

Charge-Coupled Devices (CCDs) have been traditionally used on high resolution soft X-ray spectrometers, but with their ability to increase the signal level in the detector before the readout noise of the system is added, Electron-Multiplying CCDs (EM-CCDs) have the potential to offer many advantages in soft X-ray detection. Through this signal multiplication an EM-CCD has advantages over conventioanl CCDs of

James H. Tutt; Andrew D. Holland; Neil J. Murray; Richard D. Harriss; David J. Hall; Matt Soman; Randall L. McEntaffer; James Endicott



Fast, simultaneous and robust VLF-EM data denoising and reconstruction via multivariate empirical mode decomposition  

NASA Astrophysics Data System (ADS)

The measurement of Very Low Frequency Electromagnetic (VLF-EM) is important in many different applications, i.e, environmental, archeological, geotechnical studies, etc. In recent years, improving and enhancing VLF-EM data containing complex numbers (bivariate) was presented by several authors in order to produce reliable models, generally using univariate empirical mode decomposition (EMD). Applying univariate EMD separately on each data is problematic. This results in a different number of misaligned Intrinsic Mode Functions (IMFs) which can complicate the selection of some IMFs for denoising process. Thus, a filtering method based on the multivariate empirical mode decomposition (MEMD) approach to decompose simultaneously bivariate data is proposed. In this paper we address two issues by employing the recently introduced noise assisted MEMD (N-A MEMD) for improving bivariate VLF-EM data. Firstly, the N-A MEMD to decompose bivariate measurement of the VLF-EM data into IMFs and a residue is defined as VLF-EM signal or unwanted noise. Secondly, the proposed method is used to enhance VLF-EM data and to reject unwanted noise. Finally, the proposed method is applied to a synthetic data with two added sinusoids. To demonstrate the robustness of the N-A MEMD method, the method was tested on added-noise synthetic data sets and the results were compared to the Ensemble EMD (EEMD) and Bivariate EMD (BEMD). The N-A MEMD gave more robust and accurate results than the EEMD and BEMD methods and the method required less CPU time to obtain the IMFs compared to EEMD. The method was also tested on several field data sets. The results indicate that the filtered VLF-EM data based on the N-A MEMD make the data easier to interpret and to be analyzed further. In addition, the 2D resistivity profile estimated from the inversion of filtered VLF-EM data results was appropriate to the geological condition.

Sungkono; Bahri, Ayi S.; Warnana, Dwa D.; Monteiro Santos, Fernando A.; Santosa, Bagus J.



The Soils and Groundwater – EM-20 S&T Roadmap Quality Assurance Project Plan  

SciTech Connect

The Soils and Groundwater – EM-20 Science and Technology Roadmap Project is a U.S. Department of Energy, Office of Environmental Management-funded initiative designed to develop new methods, strategies and technology for characterizing, modeling, remediating, and monitoring soils and groundwater contaminated with metals, radionuclides, and chlorinated organics. This Quality Assurance Project Plan provides the quality assurance requirements and processes that will be followed by EM-20 Roadmap Project staff.

Fix, N. J.



Apresentase neste apndice a definio de categoria cartesiana livremente gerada, apresentada em [Sernadas et al 92e]. Tal como em [Admek et al 90], assumese que  

E-print Network

'')�Mor C P desde que (s:c®c')�Mor C P e (s':c'®c'')�Mor C P ; . ((s':c®c')�(s'':c®c''):c®c'�c'')�Mor C P desde que (s':c®c')�Mor C P e (s'':c®c'')� Mor C P ; pela relação de equivalência induzida pelas, apresentada em [Sernadas et al 92e]. Tal como em [Adámek et al 90], assume­se que Cat denota a categoria de

Lisboa, Universidade Técnica de


High-speed computation of the EM algorithm for PET image reconstruction  

SciTech Connect

The PET image reconstruction based on the EM algorithm has several attractive advantages over the conventional convolution backprojection algorithms. However, two major drawbacks have impeded the routine use of the EM algorithm, namely, the long computational time due to slow convergence and the large memory required for the storage of the image, projection data and the probability matrix. In this study, the authors attempts to solve these two problems by parallelizing the EM algorithm on a multiprocessor system. The authors have implemented an extended hypercube (EH) architecture for the high-speed computation of the EM algorithm using the commercially available fast floating point digital signal processor (DSP) chips as the processing elements (PEs). The authors discuss and compare the performance of the EM algorithm on a 386/387 machine, CD 4360 mainframe, and on the EH system. The results show that the computational speed performance of an EH using DSP chips as PEs executing the EM image reconstruction algorithm is about 130 times better than that of the CD 4360 mainframe. The EH topology is expandable with more number of PEs.

Rajan, K.; Patnaik, L.M.; Ramakrishna, J. (Indian Inst. of Science, Bangalore (India))



Anisotropic 3D inversion of towed streamer EM data from the Troll West oil province (Invited)  

NASA Astrophysics Data System (ADS)

Obviating the need for ocean bottom receivers, the towed streamer EM system enables CSEM data to be acquired simultaneously with seismic over very large areas in frontier and mature basins for higher production rates and more cost effective than conventional marine CSEM. The towed streamer EM data are currently processed and delivered as a spectrum of frequency-domain responses. We apply a 3D anisotropic inversion methodology for towed streamer EM data that includes a moving sensitivity domain. Our implementation is based on the 3D contraction integral equation method for computing the EM responses and Fréchet derivatives, and uses the re-weighted regularized conjugate gradient method for minimizing the objective functional with focusing regularization. We present an actual case study for the 3D anisotropic inversion of towed streamer EM data from the Troll West oil province in the North Sea, and demonstrate our ability to image the Troll West Oil and Gas Provinces. We conclude that 3D anisotropic inversion of the data from the current generation of towed streamer EM system can adequately recover both the vertical and horizontal resistivities in anisotropic hydrocarbon-bearing formations.

Mattsson, J.; Midgley, J.; Zhdanov, M. S.; ENDO, M.



Visualizing Proteins and Macromolecular Complexes by Negative Stain EM: from Grid Preparation to Image Acquisition  

PubMed Central

Single particle electron microscopy (EM), of both negative stained or frozen hydrated biological samples, has become a versatile tool in structural biology 1. In recent years, this method has achieved great success in studying structures of proteins and macromolecular complexes 2, 3. Compared with electron cryomicroscopy (cryoEM), in which frozen hydrated protein samples are embedded in a thin layer of vitreous ice 4, negative staining is a simpler sample preparation method in which protein samples are embedded in a thin layer of dried heavy metal salt to increase specimen contrast 5. The enhanced contrast of negative stain EM allows examination of relatively small biological samples. In addition to determining three-dimensional (3D) structure of purified proteins or protein complexes 6, this method can be used for much broader purposes. For example, negative stain EM can be easily used to visualize purified protein samples, obtaining information such as homogeneity/heterogeneity of the sample, formation of protein complexes or large assemblies, or simply to evaluate the quality of a protein preparation. In this video article, we present a complete protocol for using an EM to observe negatively stained protein sample, from preparing carbon coated grids for negative stain EM to acquiring images of negatively stained sample in an electron microscope operated at 120kV accelerating voltage. These protocols have been used in our laboratory routinely and can be easily followed by novice users. PMID:22215030

Booth, David S.; Avila-Sakar, Agustin; Cheng, Yifan



Reservoir characterization and process monitoring with EM methods. 1994 Annual report  

SciTech Connect

During the past five years at Lawrence Livermore National Laboratory (LLNL) the authors have applied the EM induction method to the problem of petroleum reservoir characterization and enhanced oil recovery (EOR) monitoring. The goal is to develop practical tools for determining the electrical resistivity distribution between boreholes at a useful scale for reservoir characterization. During FY94 the authors conducted their largest field test to date. They applied crosshole and surface-to-borehole EM techniques to reservoir characterization at the Los Hills No. 3 oil field making three sets of measurements during the initial phase of the steam drive.From these data they were able to determine the resistivity and configuration of the oil sands, between the observation wells, and provide an image of the subsurface resistivity changes due to the steam drive. They also conducted a waterflood experiment at the Richmond Field Station facility using the borehole-to-surface EM technique. For this test they injected a small quantity of saltwater, and applied the Em technique to monitor the progress of the injected plume. Data collection for this experiment is complete but the results are yet to be interpreted. Finally, a project to understand EM propagation through steel casing was initiated in 1994. The goals of the experiment are to determine the limits and applications for crosswell EM surveys through steel well casing.

Wilt, M.



If EM waves don't interfere, what causes interferograms?  

NASA Astrophysics Data System (ADS)

Photonics engineers involved in designing and operating Fourier transform spectrometers (FTS) often rely on Maxwell's wave equations and time-frequency (distance-wavenumber) Fourier theory as models to understand and predict the conversion of optical energy to electrical signals in their instruments. Dr. Chandrasekhar Roychoudhuri and his colleagues, at last year's conference, presented three significant concepts that might completely change the way we comprehend the interaction of light and matter and the way interference information is generated. The first concept is his non-interaction of waves (NIW) formulation, which puts in place an optical wave description that more accurately describe the properties of the finite time and spatial signals of an optical system. The second is a new description for the cosmic EM environment that recognizes that space is really filled with the ether of classical electromagnetics. The third concept is a new metaphysics or metaphotonics that compares the photon as a particle in a void against the photon as a wave in a medium to see which best explain the twelve different aspects of light. Dr. Henry Lindner presents a compelling case that photons are waves in a medium and particles (electrons, protons, atoms) are wave-structures embedded in the new ether. Discussion of the three new principles is intended to increase the curiosity of photonics engineers to investigate these changes in the nature of light and matter.

Wellard, Stanley J.



The tidal asymmetries and residual flows in Ems Estuary  

NASA Astrophysics Data System (ADS)

A 3D unstructured-grid numerical model of the Ems Estuary is presented. The simulated hydrodynamics are compared against tidal gauge data and observations from research cruises. A comparison with an idealized test reveals the capability of the model to reproduce the secondary circulation patterns known from theoretical results. The simulations prove to be accurate and realistic, confirming and extending findings from earlier observations and modeling studies. The basic characteristics of dominant physical processes in the estuary such as tidal amplification, tidal damping, overtide generation, baroclinicity and internal mixing asymmetry are quantified. The model demonstrates an overall dominance of the flood currents in most of the studied area. However, the hypsometric control in the vicinity of Dollart Bay reverses this asymmetry, with the ebb currents stronger than the flood ones. Small-scale bathymetric characteristics and baroclinicity result in a very complex interplay between dominant physical mechanisms in different parts of the tidal channels and over the tidal flats. Residual flow reveals a clear overturning circulation in some parts of the estuary which is related to a mixing asymmetry between flood and ebb currents. We demonstrate that while areas close to the tidal river exhibit overall similarity with density controlled estuarine conditions, in large areas of the outer estuary barotropic forcing and complex bathymetry together with the density distribution affect substantially the horizontal circulation.

Pein, Johannes Ulrich; Stanev, Emil Vassilev; Zhang, Yinglong Joseph



EM modeling for GPIR using 3D FDTD modeling codes  

SciTech Connect

An analysis of the one-, two-, and three-dimensional electrical characteristics of structural cement and concrete is presented. This work connects experimental efforts in characterizing cement and concrete in the frequency and time domains with the Finite Difference Time Domain (FDTD) modeling efforts of these substances. These efforts include Electromagnetic (EM) modeling of simple lossless homogeneous materials with aggregate and targets and the modeling dispersive and lossy materials with aggregate and complex target geometries for Ground Penetrating Imaging Radar (GPIR). Two- and three-dimensional FDTD codes (developed at LLNL) where used for the modeling efforts. Purpose of the experimental and modeling efforts is to gain knowledge about the electrical properties of concrete typically used in the construction industry for bridges and other load bearing structures. The goal is to optimize the performance of a high-sample-rate impulse radar and data acquisition system and to design an antenna system to match the characteristics of this material. Results show agreement to within 2 dB of the amplitudes of the experimental and modeled data while the frequency peaks correlate to within 10% the differences being due to the unknown exact nature of the aggregate placement.

Nelson, S.D.



14-3-3 proteins are part of an abscisic acid-VIVIPAROUS1 (VP1) response complex in the Em promoter and interact with VP1 and EmBP1.  

PubMed Central

Protein-DNA complexes were formed when nuclear extracts from embryogenic rice suspension cultures or maize embryos were incubated with an abscisic acid-VIVIPAROUS1 (VP1) response element (Em1a) from the Em promoter. Monoclonal antibodies generated to GF14, a 14-3-3 protein from plants, resulted in gel retardation of the Em1a-protein complexes. Antibodies generated to the C and N termini of GF14 detected protein isoforms in rice nuclear and cytoplasmic extracts, but no differences in distribution of the GF14 isoforms were recognized between the nucleus and cytoplasm or when abscisic acid-treated and untreated tissues were compared. When recombinant GF14 fusion proteins from rice were added to nuclear extracts, novel complexes were formed that required the dimerization domain of GF14. Chemical cross-linking showed that GF-14 interacted with the basic leucine zipper factor EmBP1, which binds specifically to Em1a, and with VP1, which transactivates Em through Em1a. GF14 proteins from rice were shown to interact with VP1 in yeast through the dimerization domain of GF14. Our results indicated that GF14 interacts with both site-specific DNA binding proteins (i.e., EmBP1) and tissue-specific regulatory factors (i.e., VP1) and may provide a structural link between VP1 and the Em1a transcriptional complex. PMID:9596641

Schultz, T F; Medina, J; Hill, A; Quatrano, R S



Prevalência de adoção intra e extrafamiliar em amostras clínica e não-clínica de crianças e adolescentes Prevalence of intrafamilial and extrafamilial adoption in a clinical and non-clinical setting samples of children and adolescents  

Microsoft Academic Search

Introdução\\/Objetivos: Estudos realizados em diferentes países demonstram que a proporção de crianças e ado- lescentes adotivos atendidos em clínicas psiquiátricas é maior em relação à verificada nas demais clínicas e na população em geral. O objetivo deste estudo é verificar a prevalência de adoção em amostra clínica e não-clínica, identificando possíveis associações entre tipos de adoção (extrafamiliar e intrafamiliar) e

Lee Fu I; Eneida B Matarazzo


Programa de Ps-Graduao em Literatura, Cultura e Contemporaneidade Rua Marqus de So Vicente, 225 -Gvea -22453-900  

E-print Network

de Pós-Graduação em Literatura, Cultura e Contemporaneidade Rua Marquês de São Vicente, 225 - Gá - PROGRAMA DE P�S-GRADUA��O EM LITERATURA, CULTURA E CONTEMPORANEIDADE EDITAL;__________________________________________________________________________________________________ Programa de Pós-Graduação em Literatura, Cultura e Contemporaneidade Rua Marquês de São Vicente, 225


EM-54 Technology Development In Situ Remediation Integrated Program. Annual report  

SciTech Connect

The Department of Energy (DOE) established the Office of Technology Development (EM-50) as an element of Environmental Restoration and Waste Management (EM) in November 1989. EM manages remediation of all DOE sites as well as wastes from current operations. The goal of the EM program is to minimize risks to human health, safety and the environment, and to bring all DOE sites into compliance with Federal, state, and local regulations by 2019. EM-50 is charged with developing new technologies that are safer, more effective and less expensive than current methods. The In Situ Remediation Integrated Program (the subject of this report) is part of EM-541, the Environmental Restoration Research and Development Division of EM-54. The In Situ Remediation Integrated Program (ISR IP) was instituted out of recognition that in situ remediation could fulfill three important criteria: Significant cost reduction of cleanup by eliminating or minimizing excavation, transportation, and disposal of wastes; reduced health impacts on workers and the public by minimizing exposure to wastes during excavation and processing; and remediation of inaccessible sites, including: deep subsurfaces; in, under, and around buildings. Buried waste, contaminated soils and groundwater, and containerized wastes are all candidates for in situ remediation. Contaminants include radioactive wastes, volatile and non-volatile organics, heavy metals, nitrates, and explosive materials. The ISR IP tends to facilitate development of in situ remediation technologies for hazardous, radioactive, and mixed wastes in soils, groundwater, and storage tanks. Near-term focus is on containment of the wastes, with treatment receiving greater effort in future years.

Not Available



Noninvasive monitoring of CO2 sequestration sites using airborne EM technology  

NASA Astrophysics Data System (ADS)

Usage of conventional airborne EM methods for studies related to CO2 sequestration reservoirs have been restricted up to date due to depth and system noise limitations. Recently a family of new EM systems was developed and launched in Canada, allowing superior depth of investigation to that of the conventional EM systems. Depending on the resistivity of the area such systems are capable of recording response from targets emplaced at the depths of up to 2 kilometers below surface. These systems are powered by natural (telluric and storm lightning) EM fields and are particularly sensitive to contrast in electrical properties of the subsurface, rather than absolute values of the conductivities, which make these systems suitable for usage in both resistive and conductive environments, including the subsurface identification and mapping of gas, hydrocarbons, liquid CO2 and supercritical CO2. Based on the well log data collected at one of the proposed sequestration sites, forward modeling has been carried out in order to study which changes in electrical properties of reservoir rocks before and after the introduction of CO2 to the sequestration reservoir are sufficient to provide enough contrast so they become detectable by EM systems. The results of the modeling showed that under favourable conditions it is possible to differentiate between brine-filled reservoirs versus CO2-filled reservoir at a depth of more than 1 kilometer with the main controlling parameters being reservoir effective porosity, thickness, Total Dissolved Solids (TDS) content of the pore-filling fluid and CO2 saturation after the injection. EM surveying can play a crucial role in studies of moderately deep-seated reservoirs, specifically can assist in monitoring CO2 injection and migration and can provide some additional data regarding the CO2 saturation level. The benefits of application of these new EM systems compared with 3D reflection seismic, VSP, gravity, and other geophysical methods will also be discussed.

Kaminski, V.; Harbert, W. P.; Legault, J. M.



Intra- and extracellular regulation of activity and processing of legumain by cystatin E/M.  


Legumain, an asparaginyl endopeptidase, is up-regulated in tumour and tumour-associated cells, and is linked to the processing of cathepsin B, L, and proMMP-2. Although legumain is mainly localized to the endosomal/lysosomal compartments, legumain has been reported to be localized extracellularly in the tumour microenvironment and associated with extracellular matrix and cell surfaces. The most potent endogenous inhibitor of legumain is cystatin E/M, which is a secreted protein synthesised with an export signal. Therefore, we investigated the cellular interplay between legumain and cystatin E/M. As a cell model, HEK293 cells were transfected with legumain cDNA, cystatin E/M cDNA, or both, and over-expressing monoclonal cell lines were selected (termed M38L, M4C, and M3CL, respectively). Secretion of prolegumain from M38L cells was inhibited by treatment with brefeldin A, whereas bafilomycin A1 enhanced the secretion. Cellular processing of prolegumain to the 46 and 36 kDa enzymatically active forms was reduced by treatment with either substance alone. M38L cells showed increased, but M4C cells decreased, cathepsin L processing suggesting a crucial involvement of legumain activity. Furthermore, we observed internalization of cystatin E/M and subsequently decreased intracellular legumain activity. Also, prolegumain was shown to internalize followed by increased intracellular legumain processing and activation. In addition, in M4C cells incomplete processing of the internalized prolegumain was observed, as well as nuclear localized cystatin E/M. Furthermore, auto-activation of secreted prolegumain was inhibited by cystatin E/M, which for the first time shows a regulatory role of cystatin E/M in controlling both intra- and extracellular legumain activity. PMID:22902879

Smith, Robert; Johansen, Harald T; Nilsen, Hilde; Haugen, Mads H; Pettersen, Solveig J; Mælandsmo, Gunhild M; Abrahamson, Magnus; Solberg, Rigmor



Does contamination buildup limit throughput for automated cryoEM?  


The development of automated systems for data acquisition in cryo electron microscopy has enabled the possibility of acquiring very large number of images from a single specimen grid. We have demonstrated that over images of 250,000 single particles can be acquired in a 24 h period. This has raised questions as to whether contamination buildup on the specimen limits the quality of the data that can be acquired during these long duration experiments and also whether the data acquisition session could be extended to allow acquisition of more than 1,000,000 particles. We report here a systematic characterization of contamination of specimens maintained for long periods of time at liquid nitrogen temperatures using standard side entry cryo stages. As part of this characterization we developed a more reliable method for accurately estimating specimen ice thickness. Using the method, we were able to calibrate image contrast against ice thickness under a variety of magnifications, objective aperture positions, and defoci, and demonstrated the strong dependence of the calibration curve on these parameters. The results show the anti-contamination aperture is, as expected, critical to the prevention of contamination and that loading film into the microscope dramatically increases the contamination rate, particularly in the first 3 h after the insertion of the film box. In the absence of film, we were able to reproducibly demonstrate that the contamination rate can be limited to a rate of approximately 1 angstrom/h providing reassurance that contamination will not be a major limiting factor for long term cryoEM experiments if a CCD camera is used for the imaging. PMID:16632377

Cheng, Anchi; Fellmann, Denis; Pulokas, James; Potter, Clinton S; Carragher, Bridget



Elimination of error factors, affecting EM and seismic inversions  

NASA Astrophysics Data System (ADS)

EM or seismic data inversions are affected by many factors, which may conceal the responses from target objects. We address here the contributions from the following effects: 1) Pre-survey spectral sensitivity factor. Preliminary information about a target layer can be used for a pre-survey estimation of the required frequency domain and signal level. A universal approach allows making such estimations in real time, helping the survey crew to optimize an acquisition process. 2) Preliminary velocities' identification and their dispersions for all the seismic waves, arising in a stratified media became a fast working tool, based on the exact analytical solution. 3) Vertical gradients effect. For most layers the log data scatter, requiring an averaging pattern. A linear gradient within each representative layer is a reasonable compromise between required inversion accuracy and forward modeling complexity. 4) An effect from the seismic source's radial component becomes comparable with vertical part for explosive sources. If this effect is not taken into account, a serious modeling error takes place. This problem has an algorithmic solution. 5) Seismic modeling is often based on different representations for a source formulated either for a force or to a potential. The wave amplitudes depend on the formulation, making an inversion result sensitive to it. 6) Asymmetrical seismic waves (modified Rayleigh) in symmetrical geometry around liquid fracture come from S-wave and merge with the modified Krauklis wave at high frequencies. A detail analysis of this feature allows a spectral range optimization for the proper wave's extraction. 7) An ultrasonic experiment was conducted to show different waves appearance for a super-thin water-saturated fracture between two Plexiglas plates, being confirmed by comparison with theoretical computations. 8) A 'sandwich effect' was detected by comparison with averaged layer's effect. This opens an opportunity of the shale gas direct identification from the surface measurements.

Magomedov, M.; Zuev, M. A.; Korneev, V. A.; Goloshubin, G.; Zuev, J.; Brovman, Y.



Immunohistochemical distribution of the secretogranin II-derived peptide EM66 in the rat hypothalamus: a comparative study with jerboa.  


EM66 is a 66-amino acid peptide derived from secretogranin II, a member of granin acidic secretory protein family, by proteolytic processing. EM66 has been previously characterized in the jerboa (Jaculus orientalis) hypothalamus and its potential implication in the neuroendocrine regulation of feeding behaviour has been demonstrated. In the present study, an immunohistochemical analysis of the localization of EM66 within hypothalamic structures of rat was performed and compared to the distribution of EM66 in the jerboa hypothalamus. In the rat hypothalamus, as in the jerboa, EM66 immunostaining was detected in the parvocellular paraventricular, preoptic and arcuate nuclei, as well as the lateral hypothalamus which displayed an important density of EM66-producing neurones. However, unlike jerboa, the suprachiasmatic and supraoptic nuclei of the rat hypothalamus were devoid of cellular EM66-immunolabeling. Thus, the novel peptide EM66 may exert common neuroendocrine activities in rat and jerboa, e.g. control of food intake, and species-specific roles in jerboa such as the regulation of biological rhythms and hydromineral homeostasis. These results suggest the existence of differences between jerboas and rats in neuroendocrine regulatory mechanisms involving EM66. PMID:17240057

Boutahricht, Mohammed; Guillemot, Johann; Montero-Hadjadje, Maité; Barakat, Youssef; El Ouezzani, Seloua; Alaoui, Abdelilah; Yon, Laurent; Vaudry, Hubert; Anouar, Youssef; Magoul, Rabia



Padronização de testes neurocomportamentais para investigação da importância funcional do wulst visual em corujas buraqueiras (Athene cunicularia).  

E-print Network

??As aves têm sido utilizadas em numerosos estudos envolvendo habilidades visuo-cognitivas, constituindo um excelente modelo para a neurolobiologia comparativa. Vários estudos já demonstraram que na… (more)

Leticia Mercedes Gomes Correia Martins




E-print Network

??Este trabalho objetivou verificar os achados laboratoriais e histológicos da infecção experimental por Trypanosoma (Trypanozoon) evansi (Steel, 1885) Balbiani, 1888, em ratos (Rattus norvegicus) da… (more)

Rovaina Laureano Doyle



Pre-flight risk assessment in Emergency Medical Service (EMS) helicopters  

NASA Technical Reports Server (NTRS)

The Emergency Medical Service (EMS) industry has been the subject of several television and newspaper articles (Harvey and Jensen, 1987) which emphasized the negative aspects, (e.g., fatalities and high accident rates), rather than the life saving services performed. Until recently, the accident rate of the EMS industry has been five times as high as that of other civil helicopters. This high accident rate has been coupled with the dramatic rise in the number of programs. The industry has built from a single service at its inception in 1972, to over 180 in 1987 (Spray, 1987), to the point that 93 percent of the contiguous U.S. is now covered by some type of EMS service. These factors prompted the National Transportation Safety Board (NTSB) to study the accidents that occurred between May 11, 1978 and December 3, 1986 (NTSB, 1988). The NTSB report concluded that 'Sound pilot judgment is central to safe flight operations.' They further stated that '... factors unique to EMS helicopter operations--such as the influence of the mission itself, program competition, and EMS program management perspectives--can drastically influence pilot judgment during the EMS mission.' One of the most difficult decisions that a pilot must make is whether to accept or decline a mission. A pre-flight risk assessment system (SAFE) was developed at NASA-Ames Research Center for civil EMS operations to aid pilots in making this decision objectively. The ability of the SAFE system to predict mission risk profiles was tested at an EMS facility. The results of this field study demonstrated that the usefulness of SAFE was highly dependent on the type of mission flown. SAFE is now being modified so that it can 'learn' with each mission flown. For example, after flying a mission to a particular site, an EMS pilot would input information about this mission into the system, such as new buildings, wires, or approach procedures. Then, the next time a pilot flew a similar mission or one to the same area, this additional information would be taken into account in computing a risk assessment.

Shively, R. J.



Scalable and Interactive Segmentation and Visualization of Neural Processes in EM Datasets  

PubMed Central

Recent advances in scanning technology provide high resolution EM (Electron Microscopy) datasets that allow neuroscientists to reconstruct complex neural connections in a nervous system. However, due to the enormous size and complexity of the resulting data, segmentation and visualization of neural processes in EM data is usually a difficult and very time-consuming task. In this paper, we present NeuroTrace, a novel EM volume segmentation and visualization system that consists of two parts: a semi-automatic multiphase level set segmentation with 3D tracking for reconstruction of neural processes, and a specialized volume rendering approach for visualization of EM volumes. It employs view-dependent on-demand filtering and evaluation of a local histogram edge metric, as well as on-the-fly interpolation and ray-casting of implicit surfaces for segmented neural structures. Both methods are implemented on the GPU for interactive performance. NeuroTrace is designed to be scalable to large datasets and data-parallel hardware architectures. A comparison of NeuroTrace with a commonly used manual EM segmentation tool shows that our interactive workflow is faster and easier to use for the reconstruction of complex neural processes. PMID:19834227

Jeong, Won-Ki; Beyer, Johanna; Hadwiger, Markus; Vazquez, Amelio; Pfister, Hanspeter; Whitaker, Ross T.



Código para imageamento indireto de estrelas em sistemas binarios: simulação de variações elipsoidais e do perfil das linhas  

NASA Astrophysics Data System (ADS)

As estrelas secundárias em variáveis cataclí smicas (VCs) e binárias-x de baixa massa (BXBMs) são cruciais para o entendimento da origem, evolução e comportamento destas binárias interagentes. Elas são estrelas magneticamente ativas submetidas a condições ambientais extremas [e.g., estão muito próximas de uma fonte quente e irradiante; têm rotação extremamente rápida e forma distorcida; estão perdendo massa a taxas de 10-8-10-10 M¤/ano] que contribuem para que suas propriedades sejam distintas das de estrelas de mesma massa na seqüência principal. Por outro lado, o padrão de irradiação na face da secundária fornece informação sobre a geometria das estruturas de acréscimo em torno da estrela primária. Assim, a obtenção de imagens da superfície destas estrelas é de grande interesse astrofísico. A Tomografia Roche usa as variações no perfil das linhas de emissão/absorção da estrela secundária em função da fase orbital para mapear a distribuição de brilho em sua superfície. Neste trabalho apresentamos os resultados iniciais do desenvolvimento de um programa para o mapeamento da distribuição de brilho na superfí cie das estrelas secundárias em VCs e BXBMs com técnicas de astro-tomografia. Presentemente temos em operação um código que simula as variações no perfil das linhas em conseqüência de efeito Doppler resultante da combinação de rotação e translação de uma estrela em forma de lobo de Roche em torno do centro de massa da binária, em função da distribuição de brilho na superfície desta estrela. O código igualmente produz a curva de luz resultante das variações de aspecto da estrela em função da fase orbital (variações elipsoidais).

Souza, T. R.; Baptista, R.



An Ems-Sensitivity Factor in Maize Conditioning Albino Leaf Stripes  

PubMed Central

A description is given for a recessive EMS-sensitivity factor conditioning albino leaf stripes. In the homozygous condition, there is low frequency of spontaneous leaf stripes. EMS, depending on the concentration, increases markedly the frequency of the stripes in 100% of the treated plants. The effects of EMS, given to the seeds, starts to appear from the 6th to 7th leaf and persists in all the leaves throughout the life cycle of the M1 plants. Only about 20–25% of the M2 plants showed some variegation. These variegated M2 plants were not distributed at random among the different ear-to-row M2 rows. PMID:17248674

Efron, Y.



Evaluation model calculations with the water reactor analysis package (WRAP-EM)  

SciTech Connect

The Water Reactor Analysis Package-Evaluation Model (WRAP-EM) is a modular system of computer codes designed to provide the safety analyst with the capability of performing complete loss-of-coolant calculations for both pressurized- and boiling-water reactor systems. The system provides a licensing-type calculation capability and thus contains most of the Nuclear Regulatory Commission-Approved EM options, as described in the Code of Federal Regulations, Title 10, Part 50, Appendix K. All phases of an accident (blowdown, refill, and reflood) are modeled. The WRAP consists of modified versions of five preexisting codes (RELAP4/MOD5, GAPCON, FRAP, MOXY, and NORCOOL), the necessary interfaces to permit automatic transition from one code to the next during the transient calculations, plus a host of user-convenience features to aid the analyst faced with a multitude of EM calculations. The WRAP has been verified against both calculated and experimental results.

Gregory, M.V.; Beranek, F.



Fabs enable single particle cryoEM studies of small proteins  

PubMed Central

Summary In spite of its recent achievements, the technique of single particle electron cryomicroscopy (cryoEM) has not been widely used to study proteins smaller than 100kDa, although it is a highly desirable application of this technique. One fundamental limitation is that images of small proteins embedded in vitreous ice do not contain adequate features for accurate image alignment. We describe a general strategy to overcome this limitation by selecting a fragment antigen binding (Fab) to form a stable and rigid complex with a target protein, thus providing a defined feature for accurate image alignment. Using this approach, we determined a three-dimensional structure of a ~65 kDa protein by single particle cryoEM. Because Fabs can be readily generated against a wide range of proteins by phage display, this approach is generally applicable to study many small proteins by single particle cryoEM. PMID:22483106

Wu, Shenping; Avila-Sakar, Agustin; Kim, JungMin; Booth, David S.; Greenberg, Charles H.; Rossi, Andrea; Liao, Maofu; Li, Xueming; Alian, Akram; Griner, Sarah L.; Juge, Narinobu; Yu, Yadong; Mergel, Claudia M.; Chaparro-Riggers, Javier; Strop, Pavel; Tampe, Robert; Edwards, Robert H.; Stroud, Robert M.; Craik, Charles S.; Cheng, Yifan



OsLEA1a, a new Em-like protein of cereal plants.  


Proteins abundant in seeds during the late stages of development, late embryogenesis abundant (LEA) proteins, are associated with desiccation tolerance. More than 100 of the group I LEA genes, also termed Em genes, have been identified from plants, bacteria and animals. The wide distribution indicates the functional importance of these genes. In the present study, we characterized a novel Em-like gene, OsLEA1a of rice (Oryza sativa). The encoded OsLEA1a protein has an N-terminal sequence similar to that of other plant Em proteins but lacks a 20-mer motif that is the most significant feature of typical Em proteins. The location of the sole intron indicates that the second exon of OsLEA1a is the mutated product of a typical Em gene. Transcriptome analysis revealed OsLEA1a mainly expressed in embryos, with no or only a few transcripts in osmotic stress-treated vegetative tissues. Structural analysis revealed that the OsLEA1a protein adopts high amounts of disordered conformations in solution and undergoes desiccation-induced conformational changes. Macromolecular interaction studies revealed that OsLEA1a protein interacts with non-reducing sugars and phospholipids but not poly-l-lysine. Thus, although the OsLEA1a protein lost its 20-mer motif, it is still involved in the formation of bioglasses with non-reducing sugars or plasma membrane. However, the protein does not function as a chaperone as do other groups of hydrophilic LEA proteins. The orthologs of the OsLEA1a gene had been identified from various grasses but not in dicot plants. Genetic analysis indicated that rice OsLEA1a locates at a 193 kb segment in chromosome 1 and is conserved in several published cereal genomes. Thus, the ancestor of Em-like genes might have evolved after the divergence of monocot plants. PMID:21097897

Shih, Ming-Der; Huang, Lin-Tzu; Wei, Fu-Jin; Wu, Ming-Tsung; Hoekstra, Folkert A; Hsing, Yue-Ie C



A distribuição de velocidades na linha de visada em galáxias barradas vistas de face  

NASA Astrophysics Data System (ADS)

Com o objetivo de realizar um estudo cinemático da componente vertical de barras em galáxias, obtivemos espectros de fenda longa de alta razão S/N ao longo dos eixos maior e menor de 14 galáxias barradas vistas de face, nos telescópios de 1.52m do ESO em La Silla, Chile, e de 2.3m do Steward Observatory em Kitt Peak, Arizona. Estes dados nos permitiram determinar a distribuição de velocidades das estrelas ao longo do eixo vertical das barras e discos destes sistemas, tanto no centro como em pontos que distam cerca de 5 e 20 segundos de arco do núcleo, correspondendo a distâncias de cerca de 0.7 e 2.8 kpc, respectivamente. Desta forma, a variação radial da distribuição de velocidades também pôde ser avaliada. Este tipo de análise tem raros exemplos na literatura por ser caro em termos de tempo de telescópio. Entretanto, é de fácil justificativa, considerando que traz novas informações que podem ser utilizadas para aperfeiçoar modelos teóricos acerca da formação e evolução de galáxias. Um algoritmo por nós desenvolvido foi utilizado para obter as distribuições de velocidades como Gaussianas generalizadas (polinômios de Gauss-Hermite), o que traz um ingrediente a mais neste tipo de estudo que, tradicionalmente, se utiliza de Gaussianas puras, uma hipótese nem sempre razoável. Apresentaremos os resultados deste trabalho, que incluem um diagnóstico para a identificação de barras recém formadas, e testes para o modelo isotérmico de discos. Mostraremos que: (i) a escolha das estrelas padrão em velocidade, e dos parâmetros da Gaussiana, deve ser muito bem justificada já que tem influência significativa nos resultados; (ii) muitas galáxias apresentam uma depressão na dispersão de velocidades na região central, que pode estar associada a um disco interno; e (iii) a dispersão de velocidades é constante ao longo da barra, nos eixos maior e menor, mas cai substancialmente quando se passa da barra para o disco.

Gadotti, D. A.; de Souza, R. E.



The longitudinal study of turnover and the cost of turnover in EMS  

PubMed Central

Purpose Few studies have examined employee turnover and associated costs in emergency medical services (EMS). The purpose of this study was to quantify the mean annual rate of turnover, total median cost of turnover, and median cost per termination in a diverse sample of EMS agencies. Methods A convenience sample of 40 EMS agencies was followed over a 6 month period. Internet, telephone, and on-site data collection methods were used to document terminations, new hires, open positions, and costs associated with turnover. The cost associated with turnover was calculated based on a modified version of the Nursing Turnover Cost Calculation Methodology (NTCCM). The NTCCM identified direct and indirect costs through a series of questions that agency administrators answered monthly during the study period. A previously tested measure of turnover to calculate the mean annual rate of turnover was used. All calculations were weighted by the size of the EMS agency roster. The mean annual rate of turnover, total median cost of turnover, and median cost per termination were determined for 3 categories of agency staff mix: all paid staff, mix of paid and volunteer (mixed), and all-volunteer. Results The overall weighted mean annual rate of turnover was 10.7%. This rate varied slightly across agency staffing mix: (all-paid=10.2%, mixed=12.3%, all-volunteer=12.4%). Among agencies that experienced turnover (n=25), the weighted median cost of turnover was $71,613.75, which varied across agency staffing mix: (all-paid=$86,452.05, mixed=$9,766.65, and all-volunteer=$0). The weighted median cost per termination was $6,871.51 and varied across agency staffing mix: (all-paid=$7,161.38, mixed=$1,409.64, and all-volunteer=$0). Conclusions Annual rates of turnover and costs associated with turnover vary widely across types of EMS agencies. The study’s mean annual rate of turnover was lower than expected based on information appearing in the news media and EMS trade magazines. Findings provide estimates of two key workforce measures – turnover rates and costs – where previously none have existed. Local EMS directors and policymakers at all levels of government may find the results and study methodology useful towards designing and evaluating programs targeting the EMS workforce. PMID:20199235

Patterson, P. Daniel; Jones, Cheryl B.; Hubble, Michael W.; Carr, Matthew; Weaver, Matthew D.; Engberg, John; Castle, Nicholas



Quality assurance guidance for laboratory assessment plates in support of EM environmental sampling and analysis activities  

SciTech Connect

This document is one of several guidance documents developed to support the EM (DOE Environmental Restoration and Waste Management) Analytical Services program. Its purpose is to introduce assessment plates that can be used to conduct performance assessments of an organization`s or project`s ability to meet quality goals for analytical laboratory activities. These assessment plates are provided as non-prescriptive guidance to EM-support organizations responsible for collection of environmental data for remediation and waste management programs at DOE facilities. The assessments evaluate objectively all components of the analytical laboratory process to determine their proper selection and use.

Not Available



ModEM: A modular system for inversion of electromagnetic geophysical data  

NASA Astrophysics Data System (ADS)

We describe implementation of a modular system of computer codes for inversion of electromagnetic geophysical data, referred to as ModEM. The system is constructed with a fine level of modular granularity, with basic components of the inversion - forward modeling, sensitivity computations, inversion search algorithms, model parametrization and regularization, data functionals - interchangeable, reusable and readily extensible. Modular sensitivity computations and generic interfaces to parallelized inversion algorithms provide a ready framework for rapid implementation of new applications or inversion algorithms. We illustrate the code's versatility and capabilities for code reuse through implementation of 3D magnetotelluric (MT) and controlled-source EM (CSEM) inversions, using essentially the same components.

Kelbert, Anna; Meqbel, Naser; Egbert, Gary D.; Tandon, Kush



"Separations: Dust to Dust" or " You Can't Escape Em"  

E-print Network

"SEPARATIONS: DUST TO DUST" OR "YOU CAN'T ESCAPE EM" Robert G. Massey Office of Industrial Programs U.S. Dept. of Energy ABSTRACT Separations are recognized by industry as one of the larger, if not the largest, energy using processes..."SEPARATIONS: DUST TO DUST" OR "YOU CAN'T ESCAPE EM" Robert G. Massey Office of Industrial Programs U.S. Dept. of Energy ABSTRACT Separations are recognized by industry as one of the larger, if not the largest, energy using processes...

Massey, R. G.



E-print Network

INPE-12145-TDI/969 ANÁLISE DE EPIS�DIOS DE TORNADO EM SANTA CATARINA: CARACTERIZA��O SIN�TICA E. Análise de episódios de tornados em Santa Catarina: caracterização sinótica e mineração de dados / I. P. O(meteorologia). 3.Meteorologia sinótica. 4.Imagem de satélite. 5.Mineração de dados. 6.Paisagem. 7.Brasil. 8.Santa


A laboratory experiment on EM backscatter from Farley-Buneman and gradient drift waves  

NASA Technical Reports Server (NTRS)

Results of laboratory experiment on Bragg backscatter of 3-cm microwaves by turbulent waves driven by the Farley-Buneman and gradient drift instabilities are reported. It is noted that the study is the third in a series of laboratory experiments performed to test, under controlled conditions, prevalent ideas on EM scattering by equatorial and high-latitude ionospheric waves and irregularities. It is shown through separate backscattering from fast and slow ion beam modes that a beam of EM radiation actually provides, in backscatter, information on the spectral content of the scattering medium.

Alport, M. J.; Dangelo, N.; Pecseli, H. L.



Rotating-bed reactor as a power source for EM gun applications  

SciTech Connect

Electromagnetic gun applications of the Rotating Bed Reactor (RBR) are examined. The RBR is a compact (approx. 1 m/sup 3/), (up to several thousand MW(th)), high-power reactor concept, capable of producing a high-temperature (up to approx. 300/sup 0/K) gas stream with a MHD generator coupled to it, the RBR can generate electric power (up to approx. 1000 MW(e)) in the pulsed or cw modes. Three EM gun applications are investigated: a rail gun thruster for orbit transfer, a rapid-fire EM gun for point defense, and a direct ground-to-space launch. The RBR appears suitable for all applications.

Powell, J.; Botts, T.; Stickley, C.M.; Meth, S.



A hybrid ML-EM algorithm for calculation of maximum likelihood estimates in semiparametric shared frailty models  

Microsoft Academic Search

This paper describes a generalised hybrid ML-EM algorithm for the calculation of maximum likelihood estimates in semiparametric shared frailty models, the Cox proportional hazard models with hazard functions multiplied by a (parametric) frailty random variable. This hybrid method is much faster than the standard EM method and faster than the standard direct maximum likelihood method (ML, Newton–Raphson) for large samples.

Hien T. V. Vu; Matthew W. Knuiman



The Value of Bus Rapid Transit: Hedonic Price Analysis of the EmX in Eugene, Oregon  

E-print Network

1 The Value of Bus Rapid Transit: Hedonic Price Analysis of the EmX in Eugene, Oregon Peter of the bus rapid transit (BRT) line in the Eugene area based on changes in residential property values of the EmX in Eugene. #12;2 Table of Contents I. Introduction

Oregon, University of


Relação entre índice de massa corporal e habilidade motora grossa em crianças de quatro a seis anos  

Microsoft Academic Search

RESUMO Este estudo teve por objetivo verificar a relação entre o desem- penho em tarefas de habilidade motora grossa com o índice de massa corporal (IMC) em meninos e meninas de quatro a seis anos de idade. Para tanto, foram analisadas 27 crianças, sendo 16 meninos e 11 meninas, com idade média de 5,64 ± 0,67 anos. As crianças foram

Fabrizio Zandonadi Catenassi; Inara Marques; Carina Barbiero Bastos; Luciano Basso; Enio Ricardo Vaz Ronque; Aline Mendes Gerage



Hamartoma fibrolipomatoso e macrodistrofia lipomatosa: análise dos achados clínicos e de imagem em quatro casos, com revisão da literatura  

Microsoft Academic Search

O hamartoma fibrolipomatoso neural e a macrodistrofia lipomatosa são doenças raras, com achados de imagem característicos. Radiografias simples, estudos de ressonância magnética e prontuários médicos de quatro pacientes foram revisados. Em um paciente, foi realizada cirurgia com confirmação histopatológica. Em três pacientes, os achados clínicos e de imagem foram considerados suficientes para o diagnóstico. Descreve- mos dois casos de macrodistrofia

Rafael Darahem de Souza Coelho; Marcelo Novelino Simão; Clóvis Simão Trad



A gente mora na estrada e passeia em casa: Carga Pesada, um road-movie na TV  

Microsoft Academic Search

Resumo: O artigo em questão volta-se para uma análise do programa de televisão Carga Pesada, exibido pela Rede Globo de Televisão, distinguindo os dois períodos em que foi produzido e exibido - início da década de 80 e atual. Trata-se de compreender quais são suas influências e que estratégias de linguagens são absorvidas pelo programa. Sua relação com o cinema




Microsoft Academic Search

Primeiramente, deve-se ressaltar que a proposta desta pesquisa (que se encontra em estágio inicial e que, portanto, muitos questionamentos são apenas apontados neste texto) é uma reflexão sobre a encenação do espetáculo teatral Ponto de Partida de Gianfrancesco Guarnieri, em 1976, no Teatro TAIB (SP), numa produção de Othon Bastos Produções Artísticas e Documenta Produções Artísticas. Neste sentido, tais análises

Ludmila Sá de Freitas


Theoretical and FEM analysis of suspension and propulsion system with HTS hybrid electromagnets in an EMS Maglev model  

NASA Astrophysics Data System (ADS)

We have been constructed a proto-type electromagnetic suspension (EMS) based maglev vehicle system. The maglev concept utilizes magnetic forces for noncontact suspension, guidance and propulsion. The suspension system with high temperature superconducting (HTS) hybrid electromagnet (EM) is composed of HTS coils and normal coils, which consume little power to keep large suspension gap. The magnetic forces realize to guide the vehicle, propel the vehicle along the guide-way and assist in braking action. The proto-type EMS-based Maglev model is designed to keep the suspension gap of 20 mm. This paper presents the theoretical analysis of the maglev vehicle based on the EMS model to obtain the designing parameters for levitation and propulsion forces. The magnetic field distributions of the electromagnetic forces with hybrid EM and propulsion stator coils are analyzed based on three dimension (3D) finite element method (FEM) analysis. From the simulation results, appropriately design parameters of the suspension, guidance and propulsion were obtained.

Chung, Y. D.; Lee, C. Y.; Jang, J. Y.; Yoon, Y. S.; Ko, T. K.



O Prof. Paulo Helene Professor Titular da Universidade de So Paulo, Educador, Pesquisador renomado e respeitado Consultor. Engenheiro Civil, EPUSP. Especialista em "Patologa de las Construcciones", Instituto  

E-print Network

Califórnia em Berkeley, USA. Consultor do Concreto de Alto Desempenho HPC utilizado no Edifício mais alto do concreto bombeado no país. Autor do CD desenvolvido em colaboração com a ABCP, destinado ao projeto, Execução e Controle de Estruturas de Concreto usando HPC, publicado em 1999. Em 2002 alcançou o Recorde

Paraná, Universidade Federal do


A Spectrum of EM-Type Mantle Endmembers (Invited)  

NASA Astrophysics Data System (ADS)

It has been a quarter century since White (1985) and Zindler and Hart (1986) proposed that Sr-Nd-Pb isotope ratios of oceanic basalts can be described as mixtures of depleted mantle (DMM) with a limited number of enriched global endmember components (HIMU, EMI, EMII). While the global endmembers clearly represent extremes of the timing and magnitude of mantle chemical fractionation processes, it remains a matter of debate how the intermediate isotopic compositions are formed. (1) Do they represent mixtures between the limited number of global endmembers? (2) Do they reflect processes intermediate to those forming the global endmembers? (3) Does each intermediate composition OIB suite reflect a unique timing and type of geochemical differentiation that forms its mantle source? Each possibility has important geodynamic implications. The Earth’s mantle continuously undergoes chemical fractionation through partial melting during crust formation, and remixing through plate tectonic recycling and convection, suggesting variable timing and compositions of mantle sources forming OIB. However, such sources are likely composed of mixed lithologies (e.g. depleted peridotite and more enriched pyroxenite) and thus even extreme melt compositions might reflect mixtures of even more extreme compositions, possibly representing the global endmembers. We further address these questions based on two examples. Grande Comore Island is located on ca. 140 Ma Indian Ocean lithosphere and its lavas reflect plume-lithosphere interaction. The Grande Comore plume component has Sr-Nd-Pb isotopic compositions intermediate between HIMU and EMI, but its Os isotope ratios are extreme and among the highest measured in OIB shield building lavas. This further supports the presence of generally high Os isotope ratios in EMI and HIMU compositions. Globally in OIB, high Os isotope ratios do not correlate with lithospheric thickness, implying that high Os isotopes are not solely controlled by melt dynamics, but require variable proportions of pyroxenite/peridotite in individual OIB sources. Moreover, new isotope data from the second example, the Discovery Seamounts in the South Atlantic, reveal a continuum of compositions between the extreme EMI composition of Walvis Ridge DSDP 525A and the LOMU extreme of anomalous South Atlantic MORB related to the Discovery hotspot (Douglass et al., 1999). These compositional extremes require a range of enriched mantle compositions outside the mixing tetrahedron of the global endmembers. In the global context, each OIB suite with EM affinity appears to form a trend towards its own unique enriched mantle endmember, inconsistent with mixing between narrowly defined global endmembers. This wide spectrum of enriched mantle endmembers is consistent with a dynamic Earth that is continuously recycling varying proportions of oceanic crust and depleted peridotite, plus sediment and lower continental crust. Douglass, J., Schilling, J.-G. and Fontignie, D., 1999. J. Geophys. Res., 104: 2941-2962. White, W.M., 1985. Geology, 13: 115-118. Zindler, A. and Hart, S., 1986. Ann. Rev. Earth Planet. Sci., 14: 493-571.

Class, C.; Goldstein, S. L.; Shirey, S. B.; Le Roex, A. P.; O'Connor, J. M.; Jokat, W.



Respostas posturais à perturbação externa inesperada em judocas de diferentes níveis de habilidade  

Microsoft Academic Search

RESUMO O judô é uma modalidade esportiva na qual é requerido o con- trole eficiente do equilíbrio pelo atleta, por estar constantemente sujeito a movimentos inesperados impostos por seus adversários. Este estudo teve o objetivo de analisar as respostas posturais a uma perturbação externa inesperada de judocas (n = 20) em dois níveis de habilidade (faixas marrom e verde) e

Sheylla Kyoko Yoshitomi; Clarice Tanaka; Marcos Duarte; Fernanda Lima; Edgard Morya; Fuad Hazime



Curso de posgraduac~ao em Astrofisica Prova de admiss~ao  

E-print Network

, pergunta-se: qual m´inima dist^ancia deve separar dois pontos sobre a superf´icie lunar para que estes´ermicos - = Wciclo / QA 5 #12;onde Wciclo ´e o trabalho realizado em um ciclo de funcionamento do motor e QA ´e


Zonation of intertidal macrobenthos in the estuaries of Schelde and Ems  

Microsoft Academic Search

Based on data, collected in 1980–1990, the intertidal benthic macrofauna of the Schelde and Ems estuaries was compared. The spatial occurrence of the benthic macrofauna along the salinity gradient, including the freshwater tidal area was emphasized. Both estuaries appeared to have a very similar species composition, especially at genus level. The higher number of species observed in the Schelde estuary

T. Ysebaert; P. Meire; J. Coosen; K. Essink



EmNet: Satisfying The Individual User Through Empathic Home Networks: Summary  

E-print Network

EmNet: Satisfying The Individual User Through Empathic Home Networks: Summary John R. Lange J, Empathic Systems, Human Factors 1. INTRODUCTION Increasingly, computer systems and networks are used to run. Measuring individual user sat- isfaction online and then using such measurements directly in the control

Dinda, Peter A.


Serological (Em2-ELISA) and parasitological examinations of fox populations for Echinococcus multilocularis infections.  


Serum or body fluid samples of 1,006 foxes were investigated in an ELISA for antibodies against a highly sensitive and specific antigen (Em2-antigen) of Echinococcus multilocularis. Parasitological examinations of the intestines and simultaneous serological examinations were carried out in 505 foxes: A group of 98 blue foxes (Alopex lagopus) from Norwegian fox farms did not contain intestinal stages of E. multilocularis and was clearly sero-negative in Em2-ELISA. On the other hand in red foxes (Vulpes vulpes) originating from European areas known to be endemic for E. multilocularis the following average prevalence rates were found: 244 foxes from Southern Germany, E. multilocularis prevalence 55% and sero-prevalence 60%; 139 foxes from Austria, E. multilocularis prevalence 4% and sero-prevalence 12%. Serological identification of individual foxes with or without intestinal E. multilocularis infection was not possible. Only serological (no parasitological) examination in 402 foxes originating from endemic areas in Switzerland resulted in a sero-prevalence rate of 37%. Sero-prevalence was only 6% and 4% in 54 and 26 other foxes, respectively, originating from Swiss and German areas where E. multilocularis has not yet been reported. Negative control Norwegian (farmed) silver foxes (n = 43) were all sero-negative. The specificity of the Em2-ELISA was confirmed by negative Em2-serologies with sera from dogs infected with intestinal and tissue dwelling helminth species (with the exception of two from 24 dogs infected with E. granulosus).(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1858455

Gottstein, B; Deplazes, P; Eckert, J; Müller, B; Schott, E; Helle, O; Boujon, P; Wolff, K; Wandeler, A; Schwiete, U



Dendrite Tracking in Microscopic Images using Minimum Spanning Trees and Localized E-M  

E-print Network

Dendrite Tracking in Microscopic Images using Minimum Spanning Trees and Localized E-M Fran properties of the complete set of dendrites. The optimal tree is obtained with a modified minimum such as Neurolucida1, Imaris2 or Metamorph3 provide with pow- erful interfaces to reconstruct dendritic trees

Fleuret, François


Convergence results for the EM approach to mixtures of experts architectures \\Lambda  

E-print Network

Head: Convergence results for mixtures of experts *Address for correspondence: Michael I. Jordan, E10 to support an Initiative in Intelligent Control at MIT. Michael I. Jordan is a NSF Presidential YoungConvergence results for the EM approach to mixtures of experts architectures \\Lambda Michael I

Jordan, Michael I.


A spectral domain approach to modelling of EM scattering for Synthetic Aperture Radar target recognition  

Microsoft Academic Search

A Fourier-based technique for electromagnetic (EM) wave reconstruction with application to polarimetric airborne and spaceborne radar data exploitation is presented. The method is different from conventional modelling techniques for Synthetic Aperture Radar (SAR) applications as a result of the full electromagnetic treatment of field interactions with the scatterer, the possibility of introducing new and controllable feature classes for target classification,

R. Sabry; P. W. Vachon


390 The EMS Energy Institute at Penn State is a leading research  

E-print Network The EMS Energy Institute at Penn State is a leading research and development organization focused on energy science and engineering. We are committed to: -- Providing academic and technical leadership in the development and assessment of energy technologies, -- Providing Penn State

Lee, Dongwon


Magnetic Properties of the Basalt in Hole EM 7, Mohole Project  

Microsoft Academic Search

The average direction of the remanent magnetization of the basalt layer at the bottom of hole EM 7 is inclined 36 ø above tile horizontal, indicating that the layer is reversely magnetized. Detailed demagnetization experiments with alternating magnetic fields to 800 oer- steds peak intensity indicate that the drilling operations did not remagnetize the basalts. The natural magnetization is extremely

Allan Cox; Richard R. Doell



A row-action alternative to the EM algorithm for maximizing likelihood in emission tomography  

Microsoft Academic Search

The maximum likelihood (ML) approach to estimating the radioactive distribution in the body cross section has become very popular among researchers in emission computed tomography (ECT) since it has been shown to provide very good images compared to those produced with the conventional filtered backprojection (FBP) algorithm. The expectation maximization (EM) algorithm is an often-used iterative approach for maximizing the

Jolyon Browne; Alvaro R. De Pierro



Monte Carlo EM for Generalized Linear Mixed Models using Randomized Spherical Radial  

E-print Network

Monte Carlo EM for Generalized Linear Mixed Models using Randomized Spherical Radial Integration by Monte Carlo methods. However, in practice, the Monte Carlo sample sizes required for convergence for such methods. One solution is to use Monte Carlo approximation, as proposed by Wei and Tanner (1990

Booth, James



Microsoft Academic Search

RESUMO — O presente trabalho trata das espécies de Arales ocorrentes em lagoas de uma área do semi-árido baiano. A ordem apresenta, no local, duas famílias com cinco espécies: Lemna valdiviana Phil., Lemna aequinoctialis Welwitsch, Wolffiella lingulata (Hegelm.) Hegelm. e Wolffia columbiana Karsten (LEMNACEAE) e Pistia stratiotes L. (ARACEAE). PALAVRAS-CHAVE: Arales; plantas aquáticas; Lemnaceae; Araceae. ABSTRACT — This paper presents

Márcia Gonçalves Bezerra; Flávio França


Dynamic partnership: A new approach to EM technology commercialization and deployment  

SciTech Connect

The task of restoring nuclear defense complex sites under the U.S. Department of Energy (DOE) Environmental Management (EM) Program presents an unprecedented challenge to the environmental restoration community. Effective and efficient cleanup requires the timely development or modification of novel cleanup technologies applicable to radioactive wastes. Fostering the commercialization of these innovative technologies is the mission of EM-50, the EM Program Office of Science and Technology. However, efforts are often arrested at the {open_quotes}valley of death,{close_quotes} the general term for barriers to demonstration, commercialization, and deployment. The Energy & Environmental Research Center (EERC), a not-for-profit, contract-supported organization focused on research, development, demonstration, and commercialization (RDD&C) of energy and environmental technologies, is in the second year of a cooperative agreement with the U.S. Department of Energy (DOE) Morgantown Energy Technology Center (METC) designed to deliver EM technologies into the commercial marketplace through a unique combination of technical support, real-world demonstration, and brokering. This paper profiles this novel approach, termed {open_quotes}Dynamic Partnership,{close_quotes} and reviews the application of this concept to the ongoing commercialization and deployment of four innovative cleanup technologies. 2 tabs.

Daly, D.J.; Erickson, T.A.; Groenewold, G.H. [and others



Are you under stress in EMS. Understanding the slippery slope of burnout and PTSD.  


Burnout and PTSD are closely linked and often underreported in EMS. EMS classrooms do little or nothing to prepare providers for the inherent emotional stresses of emergency response and the "thick skin" culture of EMS may make many providers apprehensive about sharing their true feelings. Burnout is triggered by many of the same stresses that lead to the symptoms of PTSD and providers experiencing burnout that doesn't resolve within a few weeks may actually be experiencing PTSD. Be mindful of yourself and your fellow coworkers, particularly after a very traumatic response. And remember traumatic responses don't need to be as dramatic as Sept. 11, New Orleans after Hurricane Katrina or the Aurora, CO shootings to bother an EMS worker. In contrast, these are the calls where providers often receive the most attention. Instead, watch for the new father who just performed CPR on an infant the same age as his own, or the provider who just watched his or her friend die following a motor vehicle collision. Pay attention to yourself and colleagues, and be responsible and honest with yourself and others about when coping strategies are enough, and when they aren't. Finally, don't ever be afraid to seek help. PMID:23097838

Collopy, Kevin T; Kivlehan, Sean M; Snyder, Scott R




Microsoft Academic Search

The heavy-tailed Multivariate Normal Inverse Gaussian (MNIG) distribution is a recent variance-mean mixture of a multivariate Gaussian with a univariate inverse Gaussian distribution. Due to the complexity of the likelihood function, parameter estimation by direct maximization is exceedingly difficult. To overcome this problem, we propose a fast and accurate multivariate Expectation- Maximization (EM) algorithm for maximum likelihood estimation of the

Tor Arne Øigård; Alfred Hanssen; Roy Edgar Hansen


Review Article Abstract: Many plant species abort a large fraction of their em-  

E-print Network

Review Article Abstract: Many plant species abort a large fraction of their em- bryos. It has often abort- ed. Such selective embryo abortion would lead to investment of resources only in the offspring with the highest potential fit- ness. Many studies have shown that otherwise viable embryos are aborted. However

Klinkhamer, Peter


A very accurate design of monolithic inductors in a 2D EM simulator  

Microsoft Academic Search

This work discusses a strategy for the design of monolithic inductors through 2D EM simulations. Two different types of inductors are considered which were fabricated in a high frequency bipolar silicon process. The first type is an inductor on a traditional substrate with a solid n+-doped buried layer, the second type is an inductor on a substrate with an oxide

Egidio Ragonese; Giovanni Girlando; Giuseppe Palmisano



An EM Algorithm for Maximum Likelihood Estimation of Process Factor Analysis Models  

ERIC Educational Resources Information Center

In this dissertation, an Expectation-Maximization (EM) algorithm is developed and implemented to obtain maximum likelihood estimates of the parameters and the associated standard error estimates characterizing temporal flows for the latent variable time series following stationary vector ARMA processes, as well as the parameters defining the…

Lee, Taehun



Relativistic MHD in dynamical spacetimes: Improved EM gauge condition for AMR grids  

E-print Network

We recently developed a new general relativistic magnetohydrodynamic code with adaptive mesh refinement that evolves the electromagnetic (EM) vector potential (A) instead of the magnetic fields directly. Evolving A enables one to use any interpolation scheme on refinement level boundaries and still guarantee that the magnetic field remains divergenceless. As in classical EM, a gauge choice must be made when evolving A, and we chose a straightforward "algebraic" gauge condition to simplify the A evolution equation. However, magnetized black hole-neutron star (BHNS) simulations in this gauge exhibit unphysical behavior, including the spurious appearance of strong magnetic fields on refinement level boundaries. This spurious behavior is exacerbated when matter crosses refinement boundaries during tidal disruption of the NS. Applying Kreiss-Oliger dissipation to the evolution of the magnetic vector potential A slightly weakens this spurious magnetic effect, but with undesired consequences. We demonstrate via an eigenvalue analysis and a numerical study that zero-speed modes in the algebraic gauge, coupled with the frequency filtering that occurs on refinement level boundaries, are responsible for the creation of spurious magnetic fields. We show that the EM Lorenz gauge exhibits no zero-speed modes, and as a consequence, spurious magnetic effects are quickly propagated away, allowing for long-term, stable magnetized BHNS evolutions. Our study demonstrates how the EM gauge degree of freedom can be chosen to one's advantage, and that for magnetized BHNS simulations the Lorenz gauge constitutes a major improvement over the algebraic gauge.

Zachariah B. Etienne; Vasileios Paschalidis; Yuk Tung Liu; Stuart L. Shapiro



Improvement of coverage and utilization of EmOC services in southwestern Bangladesh  

Microsoft Academic Search

ObjectiveThe Government of Bangladesh has implemented safe motherhood programs throughout the country supported by the United Nations Children's Fund (UNICEF) and United Nations Population Fund (UNFPA) aimed at reducing maternal morbidity and mortality. The objective of this study is to assess the effect of the interventions on the UN emergency obstetric care (EmOC) process indicators in Khulna division, Bangladesh.

M. T. Islam; M. M. Hossain; M. A. Islam; Y. A. Haque



An EM Approach for Poisson-Gaussian Noise Modeling Anna Jezierska  

E-print Network

the associated Poisson process is nonstationary in space and also exhibits an exponential decay in time, whereas the parameters of a probability distribution constitutes a fundamental task in many statistical signal processingAn EM Approach for Poisson-Gaussian Noise Modeling Anna Jezierska , Caroline Chaux, Jean

Boyer, Edmond


Quality Control of CNT Forests via EM Probing Tianyou Kou, C. Emre Koksal, and Eylem Ekici  

E-print Network

, especially for flat-panel displays. During the process of growing the CNT forests, it is highly probable. Rather than relying on the oscillation of electrons inside the antenna in response to EM waves, CNTs was first proposed in [1] to use CNTs as non- traditional antennas to receive RF signals, further analyzed

Koksal, Can Emre


The St em Cell and Regenerat ive Medicine Cent er Post doct oral Fellowships  

E-print Network

The St em Cell and Regenerat ive Medicine Cent er Post doct oral Fellowships I. General Information and highlights the significance of the work in stem cell biology and/or regenerative medicine (1 page). #12;III: Address Line #2: City: State: Zip Code: Country: Racial/Ethnic Heritage (optional): American Indian


Concepções de policiais sobre crianças em situação de rua: um estudo sobre preconceito  

Microsoft Academic Search

Resumo O objetivo deste estudo foi investigar a concepção que policiais militares têm das crianças em situação de rua. Pela técnica da inserção ecológica, doze policiais homens foram selecionados ao acaso e entrevistados nas ruas perante um roteiro pré-estabelecido. Foi realizada uma análise qualitativa do conteúdo das entrevistas e de diários de campo dos pesquisadores. Os critérios utilizados pelos policiais

Elder Cerqueira-Santos; Sílvia H. Koller; Christian Pilz; Daniela D. Dias; Flávia Wagner




Microsoft Academic Search

ISO 14000 is considered a newcomer in the environmental management systems, but it is gradually gaining worldwide acceptance (10,000 certificates by June 1999). Although the food industry was not one of the first industrial sectors to implement EMS\\/ISO 14000, recent surveys in industrialized countries show that more than 1000 food companies worldwide have already applied the ISO 14001. The popular

Ioannis D. Boudouropoulos; Ioannis S. Arvanitoyannis



The VLF-EM imaging of potential collapse on the LUSI embankment  

NASA Astrophysics Data System (ADS)

Collapse and overtopping repeatedly occur in LUSI Embankment. Discontinuities (crack or fracture) in the embankment are major reasons for embankment failures or collapses. Very-low frequency electromagnetic (VLF-EM) measurement is essentially a non-destructive technique which displays subsurface 2-D cross section of resistivity. The cross section result has the possibility of detecting discontinuities and liquid saturation in embankment before it collapsed by observing which part of it in the cross section has low resistivity. This paper presents results of a survey conducted at the LUSI embankment in Eastern Java, Indonesia in a part of potential collapse. VLF-EM profiles measured along the embankment crest provided an overview of the whole embankment and served to detect anomalous zones. The noise assisted multivariate empirical mode decomposition (NA-MEMD) is applied to reject unwanted VLF-EM noise and Inv2DVLF software is applied to obtain result of 2-D resistivity models. In the selected area, the drill log and the standard penetration test (SPT) value gave detailed information about subsurface layer below embankment. This information is valuable for supporting 2-D resistivity image obtained from VLF-EM data inversion. Furthermore, the low resistivity in embankment layer is associated to discontinuities (fracture, crack or fault) along the embankment which caused its collapse.

Sungkono; Husein, Alwi; Prasetyo, Hardi; Bahri, Ayi S.; Monteiro Santos, Fernando A.; Santosa, Bagus J.



Accelerated Iterative Reconstruction for Positron Emission Tomography Based on the EM Algorithm for Maximum Likelihood Estimation  

Microsoft Academic Search

The EM method that was originally developed for maximum likelihood estimation in the context of mathematical statistics may be applied to a stochastic model of positron emission tomography (PET). The result is an iterative algorithm for image reconstruction that is finding increasing use in PET, due to its attractive theoretical and practical properties. Its major disadvantage is the large amount

Robert M. Lewitt; Gerd Muehllehner




Microsoft Academic Search

Resumo - Este trabalho apresenta um sistema de posicionamento automático para painéis fotovoltaicos, com o objetivo de melhorar a conversão da energia solar em energia elétrica. Um protótipo com movimentação automática foi desenvolvido e sua eficiência na geração de energia foi comparada a outro sistema com as mesmas características, porém fixo. Resultados obtidos demonstram um aumento significativo na eficiência, obtido

Alceu F. Alves; José A. Cagnon; José R. C. P. Fraga


Environmental Cost Analysis System (ECAS) Status and Compliance Requirements for EM Consolidated Business Center Contracts - 13204  

SciTech Connect

The Department of Energy (DOE) Office of Environmental Management (EM) has developed a web-accessible database to collect actual cost data from completed EM projects to support cost estimating and analysis. This Environmental Cost Analysis System (ECAS) database was initially deployed in early 2009 containing the cost and parametric data from 77 decommissioning, restoration, and waste management projects completed under the Rocky Flats Closure Project. In subsequent years we have added many more projects to ECAS and now have a total of 280 projects from 8 major DOE sites. This data is now accessible to DOE users through a web-based reporting tool that allows users to tailor report outputs to meet their specific needs. We are using it as a principal resource supporting the EM Consolidated Business Center (EMCBC) and the EM Applied Cost Engineering (ACE) team cost estimating and analysis efforts across the country. The database has received Government Accountability Office review as supporting its recommended improvements in DOE's cost estimating process, as well as review from the DOE Office of Acquisition and Project Management (APM). Moving forward, the EMCBC has developed a Special Contract Requirement clause or 'H-Clause' to be included in all current and future EMCBC procurements identifying the process that contractors will follow to provide DOE their historical project data in a format compatible with ECAS. Changes to DOE O 413.3B implementation are also in progress to capture historical costs as part of the Critical Decision project closeout process. (authors)

Sanford, P.C. [Consultant, 11221 E. Cimmarron Dr., Englewood, CO 80111 (United States)] [Consultant, 11221 E. Cimmarron Dr., Englewood, CO 80111 (United States); Moe, M.A. [EMCBC Office of Cost Estimating and Analysis, United States Department of Energy, 250 E. 5th Street, Suite 500, Cincinnati, OH 45202 (United States)] [EMCBC Office of Cost Estimating and Analysis, United States Department of Energy, 250 E. 5th Street, Suite 500, Cincinnati, OH 45202 (United States); Hombach, W.G. [Team Analysis, Inc., 2 Cardinal Park Drive, Suite 105A, Leesburg, VA 20175 (United States)] [Team Analysis, Inc., 2 Cardinal Park Drive, Suite 105A, Leesburg, VA 20175 (United States); Urdangaray, R. [Project Performance Corporation, 1760 Old Meadow Road, McLean, VA 22102 (United States)] [Project Performance Corporation, 1760 Old Meadow Road, McLean, VA 22102 (United States)



"Science affects the way we think together." SEEN ONE DAM, SEEN `EM ALL?  

E-print Network

debate about removal of dams from the Columbia and Snake Rivers, an interesting twist emerges from"Science affects the way we think together." SEEN ONE DAM, SEEN `EM ALL?: THE SURPRISING STORY of private dams will be relicensed by the Federal Energy Regulatory Commission. Many of them


PEDRO ALMODÓVAR ANALISTA DE SI MESMO?1 A movida madrileña em \\  

Microsoft Academic Search

Resumo: Este artigo analisa as primeiras produções cinematográficas de Pedro Almodóvar identificadas ao movimento artístico-cultural denominado de movida madrilena. Busca-se relacionar o que Pierre Bourdieu chama em seu livro As Regras da Arte de visão socióloga do escritor francês Gustave Flaubert, construída na obra A educação sentimental, com a hipótese de o cineasta espanhol Pedro Almodóvar também se revelar um

Meize Regina de Lucena; Gustavo Colares; Melo Carlos


Em busca da caixa mágica: o Estado Novo e a televisão  

Microsoft Academic Search

RESUMO A análise histórica sobre a Exposição de Televisão (Rio de Janeiro, 1939), evento promovido pelo Estado Novo em parce- ria com o Terceiro Reich alemão, permi- te trazer, além de dados sobre a história da TV no Brasil, elementos de compreen- são sobre as primeiras relações entre po- der político e esse meio de comunicação no país. Pois, a

Áureo Busetto



Responsabilidade Civil do Construtor e sua Aplicação em Auditoria de Obras Públicas  

Microsoft Academic Search

Em auditorias de obras públicas, diversos fatores que podem implicar a má qualidade e pouca durabilidade do trabalho não podem ser efetivamente verificados. Diversos problemas, tais quais: má qualidade de materiais, má qualidade de mão- de-obra e inadequação de projetos, que adversamente afetarão a qualidade da obra, a sua durabilidade e a sua funcionalidade, dificilmente podem ser constatados durante as

Carnot Leal Nogueira


Estimating Word Translation Probabilities from Unrelated Monolingual Corpora Using the EM Algorithm  

Microsoft Academic Search

Selecting the right word translation among several op- tions in the lexicon is a core problem for machine trans- lation. We present a novel approach to this problem that can be trained using only unrelated monolingual corpora and a lexicon. By estimating word translation probabilities using the EM algorithm, we extend upon target language modeling. We construct a word trans-

Philipp Koehn; Kevin Knight



Laboratory experiment on EM backscatter from Farley-Buneman and gradient drift waves  

SciTech Connect

Results are reported of a laboratory experiment on Bragg backscatter of 3-cm microwaves by turbulent waves driven by the Farley-Buneman and gradient drift instabilities. The present work is the third in a series of laboratory experiments performed to test, under controlled conditions, prevalent ideas on EM scattering equatorial and high-latitude ionospheric waves and irregularities.

Alport, M.J.; D'Angelo, N.; Pecseli, H.L.



G EM OF HI E MO UNTA I S 2 (piece by pieee)  

E-print Network

#12;#12;#12;#12;I ) #12;G EM OF HI E MO UNTA I S 2 (piece by pieee) student life academics #12;GEM and players alike motivated for the upcoming football game. ABOVE- Joe Vandal rings the bell in celebration people on the stage, and no pre-recorded music. FAR, LEFT - Onlookers clap as the Ul marching band

O'Laughlin, Jay


De-centralized and centralized control for realistic EMS Maglev systems  

NASA Astrophysics Data System (ADS)

A comparative study of de-centralized and centralized controllers when used with real EMS Maglev Systems is introduced. This comparison is divided into two parts. Part I is concerned with numerical simulation and experimental testing on a two ton six-magnet EMS Maglev vehicle. Levitation and lateral control with these controllers individually and when including flux feedback control in combination with these controllers to enhance stability are introduced. The centralized controller is better than the de-centralized one when the system is exposed to a lateral disturbing force such as wind gusts. The flux feedback control when combined with de-centralized or centralized controllers does improve the stability and is more resistant and robust with respect to the air gap variations. Part II is concerned with the study of Maglev vehicle-girder dynamic interaction system and the comparison between these two controllers on this typical system based on performance and ride quality achieved. Numerical simulations of the ODU EMS Maglev vehicle interacting with girder are conducted with these two different controllers. The de-centralized and centralized control for EMS Maglev systems that interact with a flexible girder provides similar ride quality. Centralized control with flux feedback could be the best controller for the ODU Maglev system when operating on girder. The centralized control will guarantee the suppression of the undesired lateral displacements; hence it will provide smoother ride quality. Flux feedback will suppress air gap variations due to the track discontinuities.

Moawad, Mohamed M. Aly M.


A caminho do topo Criar em Portugal uma universidade de dimenso mdia no plano europeu,  

E-print Network

Lisboa (a antiga "Cl�ssica") e T�cnica de Lisboa teve o objetivo de criar uma nova institui��o: a maior (a antiga "Cl�ssica") com a Universidade T�cnica de Lisboa. Que cuidados foram necess�rios ter em

Instituto de Sistemas e Robotica


External Resource: Earth-Moon-Sun Dynamics: Building the EMS Model  

NSDL National Science Digital Library

In this unit of study, students participate in iterative model building as they encounter patterns in various celestial phenomena and attempt to provide a causal explanation for them. Each of the six materials within Building the EMS Model focuses on a di



Precision and accuracy of regional radioactivity quantitation using the maximum likelihood EM reconstruction algorithm  

Microsoft Academic Search

The imaging characteristics of maximum likelihood (ML) reconstruction using the EM algorithm for emission tomography have been extensively evaluated. There has been less study of the precision and accuracy of ML estimates of regional radioactivity concentration. The authors developed a realistic brain slice simulation by segmenting a normal subject's MRI scan into gray matter, white matter, and CSF and produced

Richard E. Carson; Yuchen Yan; BettyAnn Chodkowski; Tieng K. Yap; Margaret E. Daube-Witherspoon



UFF/PROGEPE/CASQ/DPVS Diviso de Promoo e Vigilncia em Sade-DPVS  

E-print Network

fumantes sendo 47% homens e 12% mulheres. No Brasil, em pesquisa recente do INCA/MS, os dados apontaram para 18,8% da população brasileira como fumante, sendo 22,7% homens e 16% mulheres. Também no Brasil

Souza, Max O.


Longer term impacts of transformed courses on student conceptual understanding of E&M  

NSDL National Science Digital Library

We have measured upper-division physics majors' performance using two research-based conceptual instruments in E&M, the BEMA and the CUE (Colorado Upper Division Electrostatics assessment.) The BEMA has been given pre/post in freshman E&M (Physics II) courses, and the BEMA and CUE have been given pre/post in several upper-division E&M courses. Some of these data extend over 10 semesters. We used PER-based techniques to transform the introductory and upper-division courses starting in Fall 2004 and 2007, respectively. Our longitudinal data allow us to measure "fade" on BEMA performance between freshman and junior year. We investigate the effects of curricula on students by comparing juniors who were enrolled in traditional vs. transformed physics as freshmen, as well as those who were enrolled in traditional or transformed upper-division E&M I, using both BEMA and CUE measures. We find that while freshman reforms significantly impact BEMA scores, junior-level reforms affect CUE but not BEMA outcomes.

Pollock, Steven J.; Chasteen, Stephanie V.



EM+TV for Reconstruction of Cone-beam CT with Curved Detectors using GPU  

E-print Network

EM+TV for Reconstruction of Cone-beam CT with Curved Detectors using GPU Jianwen Chen, Ming Yan with CT is significant. Methods that can enable CT imaging at reduced radiation exposure without improved reconstruction at lower radiation exposure levels. The method is based on the combination of 1

Cong, Jason "Jingsheng"


Medicina Baseada em Evidências: a arte de aplicar o conhecimento científico na prática clínica  

Microsoft Academic Search

RESUMO - Este artigo foi escrito com o objetivo de descrever o conceito de Medicina Baseada em Evidências (MBE) e as competências necessárias para a sua prática. MBE deve ser vista como a integração da experiência clínica com a capacida- de de analisar e aplicar racionalmente a informa- ção científica ao cuidar de pacientes. A aplicação de métodos e estratégias

A. A. Lopes



Crosshole EM for oil field characterization and EOR monitoring: Field examples from Lost Hills, California  

Microsoft Academic Search

A steamflood recently initiated by Mobil Development and Production U.S. at the Lost Hills No 3 oil field in California is notable for its shallow depth and the application of electromagnetic (EM) geophysical techniques to monitor the subsurface steam flow. Steam was injected into three stacked eastward-dipping unconsolidated oil sands at depths from 60 to 120 m; the plume is

Michael Wilt; Clifford Schenkel; Michael Wratcher; Ilia Lambert; Carlos Torres-Verdin; Tseng H. W



Color fusion based on EM algorithm for IR and visible image  

Microsoft Academic Search

As two of the most commonly used image sensors in night-vision for military applications, infrared (IR) and visible light cameras have their own advantages and limitations due to the physical differences between the image formation processes. In this paper, a new multi-scale scheme for color image fusion is presented using EM algorithm and color transfer algorithm for IR and visible

Gang Liu; Guohong Huang



Data for Environmental Modeling (D4EM): Background and Applications of Data Automation  

EPA Science Inventory

The Data for Environmental Modeling (D4EM) project demonstrates the development of a comprehensive set of open source software tools that overcome obstacles to accessing data needed by automating the process of populating model input data sets with environmental data available fr...


Nonorthogonal PEEC formulation for time- and frequency-domain EM and circuit modeling  

Microsoft Academic Search

Electromagnetic solvers based on the partial element equivalent circuit (PEEC) approach have proven to be well suited for the solution of combined circuit and EM problems. The inclusion of all types of Spice circuit elements is possible. Due to this, the approach has been used in many different tools. Most of these solvers have been based on a rectangular or

Albert E. Ruehli; Giulio Antonini; Joris Esch; Jonas Ekman; Anita Mayo; Antonio Orlandi



Reduction of EMI for oblique incidence of em waves — A case study  

Microsoft Academic Search

Reducti on of Electromagnetic Interference (EM I), i.e., shielding effectiveness of different shields against the angle of incidence with conductors and conductive polymers using plane­ wave theory are carried out. The plane wave shielding effectiveness of new combination of these materials is evaluated as a function of angle of incidence for the single shield. With recent advancements in synthesizing stable

K Brahmananda Reddy; JVS Srikanth Prasad; Ande Srikanth; K Ajit Kishan



KEY AND SUPPLEMENTARY COMPARISONS: RMO comparison final report: 2006-2007 Resistance standards comparison between SIM laboratories. SIM.EM-K1, 1 ? SIM.EM-K2, 1 G? SIM.EM-S6, 1 M?  

NASA Astrophysics Data System (ADS)

The Working Group for Electricity and Magnetism of the Inter-American Metrology System (SIM) initiated the key and supplemental regional comparisons SIM.EM-K1-K2-S6 to provide the first internationally recognized comparisons of precision resistance measurements for nations of the western hemisphere. These comparisons include the official metrology institutes of six members of SIM and follow the guidelines for key comparisons under the 1999 CIPM Mutual Recognition Arrangement (MRA). The National Institute of Standards and Technology (NIST) provided the comparison standards and acted as the pilot laboratory in the SIM.EM-K1-K2-S6 comparisons, which began in January 2006 and were completed in September 2007. By means of procedures for linking key comparison data, the SIM.EM-K1-K2 comparisons will help to provide assurance of equality in measurements between the nations organized in SIM and the participants in the CCEM key comparisons. The analysis included in this report (Appendix A) specifically provides methods for calculating the degrees of equivalence and their uncertainties between the national measurement standards of the participating laboratories (Appendix B). A subsequent analysis (Appendix G) provides methods and results linking this regional comparison to CCEM key comparison CCEM-K2 and a recent BIPM-NIST bilateral comparison at the 1 ? level. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

Elmquist, R. E.; Jarrett, D. G.; Zhang, N. F.



Cramer-Rao lower bound optimization of an EM-CCD-based scintillation gamma camera  

NASA Astrophysics Data System (ADS)

Scintillation gamma cameras based on low-noise electron multiplication (EM-)CCDs can reach high spatial resolutions. For further improvement of these gamma cameras, more insight is needed into how various parameters that characterize these devices influence their performance. Here, we use the Cramer-Rao lower bound (CRLB) to investigate the sensitivity of the energy and spatial resolution of an EM-CCD-based gamma camera to several parameters. The gamma camera setup consists of a 3 mm thick CsI(Tl) scintillator optically coupled by a fiber optic plate to the E2V CCD97 EM-CCD. For this setup, the position and energy of incoming gamma photons are determined with a maximum-likelihood detection algorithm. To serve as the basis for the CRLB calculations, accurate models for the depth-dependent scintillation light distribution are derived and combined with a previously validated statistical response model for the EM-CCD. The sensitivity of the lower bounds for energy and spatial resolution to the EM gain and the depth-of-interaction (DOI) are calculated and compared to experimentally obtained values. Furthermore, calculations of the influence of the number of detected optical photons and noise sources in the image area on the energy and spatial resolution are presented. Trends predicted by CRLB calculations agree with experiments, although experimental values for spatial and energy resolution are typically a factor of 1.5 above the calculated lower bounds. Calculations and experiments both show that an intermediate EM gain setting results in the best possible spatial or energy resolution and that the spatial resolution of the gamma camera degrades rapidly as a function of the DOI. Furthermore, calculations suggest that a large improvement in gamma camera performance is achieved by an increase in the number of detected photons or a reduction of noise in the image area. A large noise reduction, as is possible with a new generation of EM-CCD electronics, may improve the energy and spatial resolution by a factor of 1.5.

Korevaar, Marc A. N.; Goorden, Marlies C.; Beekman, Freek J.



Cramer-Rao lower bound optimization of an EM-CCD-based scintillation gamma camera.  


Scintillation gamma cameras based on low-noise electron multiplication (EM-)CCDs can reach high spatial resolutions. For further improvement of these gamma cameras, more insight is needed into how various parameters that characterize these devices influence their performance. Here, we use the Cramer-Rao lower bound (CRLB) to investigate the sensitivity of the energy and spatial resolution of an EM-CCD-based gamma camera to several parameters. The gamma camera setup consists of a 3 mm thick CsI(Tl) scintillator optically coupled by a fiber optic plate to the E2V CCD97 EM-CCD. For this setup, the position and energy of incoming gamma photons are determined with a maximum-likelihood detection algorithm. To serve as the basis for the CRLB calculations, accurate models for the depth-dependent scintillation light distribution are derived and combined with a previously validated statistical response model for the EM-CCD. The sensitivity of the lower bounds for energy and spatial resolution to the EM gain and the depth-of-interaction (DOI) are calculated and compared to experimentally obtained values. Furthermore, calculations of the influence of the number of detected optical photons and noise sources in the image area on the energy and spatial resolution are presented. Trends predicted by CRLB calculations agree with experiments, although experimental values for spatial and energy resolution are typically a factor of 1.5 above the calculated lower bounds. Calculations and experiments both show that an intermediate EM gain setting results in the best possible spatial or energy resolution and that the spatial resolution of the gamma camera degrades rapidly as a function of the DOI. Furthermore, calculations suggest that a large improvement in gamma camera performance is achieved by an increase in the number of detected photons or a reduction of noise in the image area. A large noise reduction, as is possible with a new generation of EM-CCD electronics, may improve the energy and spatial resolution by a factor of 1.5. PMID:23552717

Korevaar, Marc A N; Goorden, Marlies C; Beekman, Freek J



The Distance to SN 1999em in NGC 1637 from the Expanding Photosphere Method  

E-print Network

We present 30 optical spectra and 49 photometric epochs sampling the first 517 days after discovery of supernova (SN) 1999em, and derive its distance through the expanding photosphere method (EPM). SN 1999em is shown to be a Type II-plateau (II-P) event, with a photometric plateau lasting until about 100 days after explosion. We identify the dominant ions responsible for most of the absorption features seen in the optical portion of the spectrum during the plateau phase. We find the distance to SN 1999em to be D = 8.2 +/- 0.6 Mpc, with an explosion date of 5.3 +/- 1.4 days before discovery. We examine potential sources of systematic error in EPM-derived distances, and find the most significant to result from uncertainty in the theoretical modeling of the flux distribution emitted by the SN photosphere (i.e., the ``flux dilution factor''). We compare previously derived EPM distances to 5 SNe II in galaxies for which a recently revised Cepheid distance exists from the HST Key Project and find D(Cepheids) / D(EPM) = 0.96 +/- 0.09. Finally, we investigate the possible use of SNe II-P as standard candles and find that for 8 photometrically confirmed SNe II-P with previously derived EPM distances and SN 1999em, the mean plateau absolute brightness is M_V(plateau) = -16.4 +/- 0.6 mag, implying that distances good to ~30% (1-sigma) may be possible without the need for a complete EPM analysis. At M_V(plateau) = -15.9 +/- 0.2 mag, SN 1999em is somewhat fainter than the average SN II-P. The general consistency of absolute SNe II-P brightness during the plateau suggests that the standard candle assumption may allow SNe II-P to be viable cosmological beacons at z > 2.

Douglas C. Leonard; Alexei V. Filippenko; Elinor L. Gates; Weidong Li; Ronald G. Eastman; Aaron J. Barth; Schelte J. Bus; Ryan Chornock; Alison L. Coil; Sabine Frink; Carol A. Grady; Alan W. Harris; Matthew A. Malkan; Thomas Matheson; Andreas Quirrenbach; Richard R. Treffers



Marine EM inversion using unstructured grids and a parallel adaptive finite element method  

NASA Astrophysics Data System (ADS)

Marine electromagnetic (EM) methods are increasingly being used for mapping tectonic structures and offshore resources. While the ability to collect dense 2D profiles and 3D grids of multi-frequency, multi-component data has grown significantly in industry and academia during the past decade, the ability to accurately and efficiently model this data remains a significant computational challenge. To date, most non-linear inversion algorithms applied for marine EM problems have relied on some form of rectangular grids for both the inversion model parameters and the finite-element (FE) or finite-difference discretization of the differential equations; often the same grid is used for both. This work explores the use of unstructured grids for two-dimensional marine EM inversion. Here the inversion minimization is based on the Occam approach but the parameterization is instead defined using arbitrarily shaped polygonal regions. Such a model discretization overcomes many of the shortcomings of rectangular grids. It readily allows for the accurate inclusion of known complex structures (e.g., seafloor bathymetry and seismic surfaces); it also allows for a more efficient model discretization since the parameter density can be concentrated (and refined) only where required. Due to the wide availability of robust triangulation algorithms, constrained conforming Delaunay triangulations are a convenient tool for generating an unstructured model discretization. The forward problem is implemented with a parallel adaptive finite element (FE) method that automatically generates an unstructured triangular FE grid that conforms to the model parameter boundaries. The FE grid is then automatically refined until the FE solution obtains an user specified tolerance. This inversion methodology has been implemented in a single code that handles both the magnetotelluric and controlled-source EM modeling problems. Along with a few synthetic examples that demonstrate the advantages of unstructured grid inversions, this algorithm is applied to a publicly available marine EM data set collected at Hydrate Ridge.

Key, K. W.



Fabrication of carbon films with ? 500nm holes for cryo-EM with a direct detector device.  


Single particle electron cryomicroscopy (cryo-EM) is often performed using EM grids coated with a perforated or holey layer of amorphous carbon. Regular arrays of holes enable efficient cryo-EM data collection and several methods for the production of micropatterned holey-carbon film coated grids have been described. However, a new generation of direct detector device (DDD) electron microscope cameras can benefit from hole diameters that are smaller than currently available. Here we extend a previously proposed method involving soft lithography with a poly(dimethylsiloxane) (PDMS) stamp for the production of holey-carbon film coated EM grids. By incorporating electron-beam (e-beam) lithography and modifying the procedure, we are able to produce low-cost high-quality holey-carbon film coated EM grids with ?500nm holes spaced 4?m apart centre-to-centre. We demonstrate that these grids can be used for cryo-EM. Furthermore, we show that by applying image shifts to obtain movies of the carbon regions beside the holes after imaging the holes, the contrast transfer function (CTF) parameters needed for calculation of high-resolution cryo-EM maps with a DDD can be obtained efficiently. PMID:24269484

Marr, Chelsea R; Benlekbir, Samir; Rubinstein, John L




PubMed Central

Objetivo Realizar uma análise da inserção da ética e humanidades no currículo do Curso de Medicina da Escola Superior em Ciências da Saúde - ESCS, escola pública do Distrito Federal, Brasil, de forma a contribuir com o processo de gestão curricular. Metodologia O Estudo é de coorte e documental. Foram pesquisados 37 termos relacionados à ética e 36 referentes à humanização nos objetivos educacionais e conteúdo dos módulos temáticos, habilidades e atitudes e interação ensino-serviço-comunidade, de 1a a 4a série e no programa do internato no currículo (ano 2006) e no projeto pedagógico do Curso de Medicina (2001). Resultados Maior inserção da humanização, ética e bioética na 1a e 2a série, quando comparado à inserção na 3a e 4a série e no internato, (IC95%-?=0,034, pvalue=0,007). Unidade de habilidades e atitudes: freqüência das 3 temáticas no currículo da 1a a 4a séries (IC95%-?=0,026, pvalue=0,013). Quando comparada a inserção entre o internato e as quatro primeiras séries, observa-se que nestas a inserção da temática humanização é superior (IC95%-?=0,042, pvalue=0,029). Conclusão O currículo desenvolvido no ano de 2006 na ESCS apresentou correlação com o projeto pedagógico do curso e contemplou a temática de forma abrangente, em todas as séries e internato. PMID:20396594

Novaes, Maria Rita Carvalho Garbi; Novaes, Luiz Carlos Garcez; Guilhem, Dirce; Lolas, Fernando; Silveira, Carla; Guiotti, Murilo




SciTech Connect

The U. S. Department of Energy's (DOE) Office of Environmental Management (EM) has the responsibility for cleaning up 60 sites in 22 states that were associated with the legacy of the nation's nuclear weapons program and other research and development activities. These sites are unique and many of the technologies needed to successfully disposition the associated wastes have yet to be developed or would require significant re-engineering to be adapted for future EM cleanup efforts. In 2008, the DOE-EM Engineering and Technology Program (EM-22) released the Engineering and Technology Roadmap in response to Congressional direction and the need to focus on longer term activities required for the completion of the aforementioned cleanup program. One of the strategic initiatives included in the Roadmap was to enhance long term performance monitoring as defined by 'Develop and deploy cost effective long-term strategies and technologies to monitor closure sites (including soil, groundwater, and surface water) with multiple contaminants (organics, metals and radionuclides) to verify integrated long-term cleanup performance'. To support this long-term monitoring (LTM) strategic initiative, EM 22 and the Savannah River National Laboratory (SRNL) organized and held an interactive symposia, known as the 2009 DOE-EM Long-Term Monitoring Technical Forum, to define and prioritize LTM improvement strategies and products that could be realized within a 3 to 5 year investment time frame. This near-term focus on fundamental research would then be used as a foundation for development of applied programs to improve the closure and long-term performance of EM's legacy waste sites. The Technical Forum was held in Atlanta, GA on February 11-12, 2009, and attended by 57 professionals with a focus on identifying those areas of opportunity that would most effectively advance the transition of the current practices to a more effective strategy for the LTM paradigm. The meeting format encompassed three break-out sessions, which focused on needs and opportunities associated with the following LTM technical areas: (1) Performance Monitoring Tools, (2) Systems, and (3) Information Management. The specific objectives of the Technical Forum were to identify: (1) technical targets for reducing EM costs for life-cycle monitoring; (2) cost-effective approaches and tools to support the transition from active to passive remedies at EM waste sites; and (3) specific goals and objectives associated with the lifecycle monitoring initiatives outlined within the Roadmap. The first Breakout Session on LTM performance measurement tools focused on the integration and improvement of LTM performance measurement and monitoring tools that deal with parameters such as ecosystems, boundary conditions, geophysics, remote sensing, biomarkers, ecological indicators and other types of data used in LTM configurations. Although specific tools were discussed, it was recognized that the Breakout Session could not comprehensively discuss all monitoring technologies in the time provided. Attendees provided key references where other organizations have assessed monitoring tools. Three investment sectors were developed in this Breakout Session. The second Breakout Session was on LTM systems. The focus of this session was to identify new and inventive LTM systems addressing the framework for interactive parameters such as infrastructure, sensors, diagnostic features, field screening tools, state of the art characterization monitoring systems/concepts, and ecosystem approaches to site conditions and evolution. LTM systems consist of the combination of data acquisition and management efforts, data processing and analysis efforts and reporting tools. The objective of the LTM systems workgroup was to provide a vision and path towards novel and innovative LTM systems, which should be able to provide relevant, actionable information on system performance in a cost-effective manner. Two investment sectors were developed in this Breakout Session. The last Breakout Session of the Technical Forum

Mayer, J.



F589 -QUINTA LISTA DE EXERCICIOS 1. Mostre, para um atomo de Thompson, que um eletron que esta em movimento em  

E-print Network

F589 - QUINTA LISTA DE EXERC´ICIOS 1. Mostre, para um ´atomo de Thompson, que um el´etron que est part´icula de 5.30 MeV ´e espalhada por um ^angulo de 60 graus ao passar por uma fina folha met. Mostre que a frequ^encia de rota¸c~ao de um el´etron em um ´atomo no modelo de hidrog^enio de Bohr ´e

de Aguiar, Marcus A. M.


[Evaluation of the diagnostic value of the ELISA tests developed by using EgHF, Em2 and EmII/3-10 antigens in the serological diagnosis of alveolar echinococcosis].  


Alveolar echinococcosis (AE), caused by larva stage of Echinococcus multilocularis, is one of the lethal parasitic diseases of man and a major public health problem in many countries in the northern hemisphere. When the living conditions and habits in Turkey were considered in terms of relation with the life cycle of the parasite, it was suggested that AE has been much more common than reported mainly from the Eastern Anatolia region of Turkey. Since in vitro serologic diagnosis tests with high specificity for AE have not been used in our country, most of the cases with liver lesions were misdiagnosed by radiological investigations as malignancies. The aim of this study was to evaluate the diagnostic value of the in-house ELISA methods developed by using three different antigens (EgHF, Em2, EmII/3-10) in the serological diagnosis of AE. The study samples included a total of 100 sera provided by Bern University Parasitology Institute where samples were obtained from patients with helminthiasis and all were confirmed by clinical, parasitological and/or histopathological means. Ten samples from each of the cases infected by E.multilocularis, E.granulosus, Taenia solium, Wuchereria bancrofti, Strongyloides stercolaris, Ascaris lumbricoides, Toxocara canis, Trichinella spiralis, Fasciola hepatica and Schistosoma haematobium were studied. In the study, EgHF (E.granulosus hydatid fluid) antigens were prepared in our laboratory from the liver cyst fluids of sheeps with cystic echinococcosis, however Em2 (E.multilocularis metacestode-purified laminated layer) and EmII/3-10 (E.multilocularis recombinant protoscolex tegument) antigens were provided by Bern University Parasitology Institute. Flat bottom ELISA plates were covered with EgHF, Em2 and EmII/3-10 antigens in the concentrations of 2.5 µg, 1 µg and 0.18 µg per well, respectively, and all sera were tested by EgHF-ELISA, Em2-ELISA and EmII/3-10-ELISA methods. For each tests, the samples which were reactive above the cut-off value (mean OD of negative controls+2 SD) were accepted as positive. The sensitivity of the ELISA tests performed with EgHF, Em2 and Em2II/3-10 antigens were estimated as 100%, 90% and 90%, respectively, whereas the specificity were 63%, 91% and 91%, respectively. When Em2-ELISA and EmII/3-10-ELISA tests were evaluated together, the specificity increased to 96%. Our data indicated that the highest sensitivity (100% with EgHF-ELISA) and specificity (96% with Em2-ELISA + EmII/3-10-ELISA) for the serodiagnosis of AE can be achieved by the combined use of the ELISA tests with three different antigens. It was concluded that the early and accurate diagnosis of AE in our country which is endemic for that disease, could be supported by the use of highly specific serological tests such as Em2-ELISA ve EmII/3-10-ELISA contributing radiological data. PMID:25052112

Pekta?, Bayram; Altinta?, Nazmiye; Akpolat, Nezahat; Gottstein, Bruno



Center Publications (Updated April 2009) Kirchner SC and Faustman EM. Identifying mechanisms of developmental toxicity: Application of tools from  

E-print Network

glutathione in methylmercury-induced toxicity in embryonic neuronal cells. Neurotoxicology. 1999: 20(5): 793 RN and Faustman EM. Human variability in mercury toxicokinetics and steady state biomarker ratios

Washington at Seattle, University of


p1 RJM 18/09/13 SE1EM11 Differentiation and Integration Part A Dr Richard Mitchell 2013  

E-print Network

on Blackboard for module SE1EM11 where also a discussion board ask / answer questions here If lose notes, spare ­ In (changing) from CD, Out to Loudspeaker Car ­ driver press accelerator, velocity change gradually Aircraft

Mitchell, Richard


"Avaliação clínica do crescimento gengival induzido por ciclosporina-A e tacrolimus em indivíduos transplantados renais: estudo prospectivo".  

E-print Network

??Este estudo teve como objetivos avaliar a ocorrência de crescimento gengival derivado da administração de duas drogas imunossupressoras ciclosporina-A (CsA) e tacrolimus, em indivíduos transplantados… (more)

Ricardo Takiy Sekiguchi



Noise models and cryo-EM drift correction with a direct-electron camera  

PubMed Central

Blurring due to specimen-holder drift is a common occurrence in cryo-EM images. Cameras employing active-pixel sensors are capable of high frame rates such that a single low-dose exposure can be acquired as a series of frames. In this paper we consider the possibility of tracking and compensating for overall drift in typical single-particle specimens through the analysis of frame sequences. A problem that arises in tracking through cross-correlation of frames obtained with the DE-12 camera from Direct Electron LLC is the presence of “hot-pixel noise”. This random pattern of bright pixels is highly correlated among frames. We show how a model of this noise can be employed to greatly reduce its effects. A filter function is derived that optimizes the tracking of image shifts by cross-correlation, and we demonstrate the tracking of specimen drift in typical cryo-EM specimens. PMID:23748163

Shigematsu, H.; Sigworth, F. J.



Helicopter EMS Transport Outcomes Literature: Annotated Review of Articles Published 2007–2011  

PubMed Central

Helicopter EMS (HEMS) and its possible association with outcomes improvement continues to be a subject of discussion. As is the case with other scientific discourse, debate over HEMS usefulness should be framed around an evidence-based assessment of the relevant literature. In an effort to facilitate the academic pursuit of assessment of HEMS utility, in late 2000 the National Association of EMS Physicians' (NAEMSP) Air Medical Task Force prepared annotated bibliographies of the HEMS-related outcomes literature. As a result of that work, two review articles, one covering HEMS use in nontrauma and the other in trauma, published in 2002 in Prehospital Emergency Care surveyed HEMS outcomes-related literature published between 1980 and mid-2000. The project was extended with two subsequent reviews covering the literature through 2006. This review continues the series, outlining outcomes-associated HEMS literature for the three-year period 2007 through the first half of 2011. PMID:22288016

Brown, Brandon S.; Pogue, Korby A.; Williams, Emily; Hatfield, Jesse; Thomas, Matthew; Arthur, Annette; Thomas, Stephen H.



A hybrid learning scheme combining EM and MASMOD algorithms for fuzzy local linearization modeling.  


Fuzzy local linearization (FLL) is a useful divide-and-conquer method for coping with complex problems such as modeling unknown nonlinear systems from data for state estimation and control. Based on a probabilistic interpretation of FLL, the paper proposes a hybrid learning scheme for FLL modeling, which uses a modified adaptive spline modeling (MASMOD) algorithm to construct the antecedent parts (membership functions) in the FLL model, and an expectation-maximization (EM) algorithm to parameterize the consequent parts (local linear models). The hybrid method not only has an approximation ability as good as most neuro-fuzzy network models, but also produces a parsimonious network structure (gain from MASMOD) and provides covariance information about the model error (gain from EM) which is valuable in applications such as state estimation and control. Numerical examples on nonlinear time-series analysis and nonlinear trajectory estimation using FLL models are presented to validate the derived algorithm. PMID:18244362

Gan, Q; Harris, C J



3D EM imaging from a single borehole; a numerical feasibility study  

SciTech Connect

Often the drilling of an oil well is followed by a logging process to characterize the region immediately surrounding the well bore. The electromagnetic (EM) induction tool, which provides the formation resistivity, is among the most frequently run logs. A preliminary study has been conducted to analyze the feasibility of three dimensional (3D) electromagnetic (EM) imaging from a single borehole. The logging tool consists of a vertical magnetic dipole source and multiple 3 component magnetic field receivers offset at different distances from the source. Synthetic data calculated with a 3D finite difference code demonstrate that the phase of the horizontal magnetic fields provides the critical information on the three dimensionality of the medium. A 3D inversion algorithm is then employed to demonstrate the plausibility of 3D inversion using 3 component magnetic field data. Finally, problems associated with introducing biased noise into the horizontal components of the field through misalignment of the logging tool is discussed.

Alumbaugh, D.L. [Sandia National Labs., Albuquerque, NM (United States); Wilt, M.J. [ElectroMagnetic Instruments, Inc., Richmond, CA (United States)



Tapping into Juniorsâ Understanding of E&M: The Colorado Upper-Division Electrostatics (CUE) Diagnostic  

NSDL National Science Digital Library

As part of an effort to systematically improve our junior-level E&M I course, we are developing a tool to assess student learning of E&M concepts at the upper-division. Along with a faculty working group, we established a list of learning goals for the course that, with student observations and interviews, served as a guide in creating the Colorado Upper-Division Electrostatics (CUE) assessment. The result is a 17-question open-ended post-test (with an optional 7-question pre-test) diagnostic, and accompanying grading rubric. We present the preliminary validation of the instrument and rubric, plus results from 226 students in 4 semesters at the University of Colorado, and 4 additional universities.

Chasteen, Stephanie V.; Pollock, Steven J.



A fully automated approach to segmentation of irregularly shaped cellular structures in EM images.  


While there has been substantial progress in segmenting natural images, state-of-the-art methods that perform well in such tasks unfortunately tend to underperform when confronted with the different challenges posed by electron microscope (EM) data. For example, in EM imagery of neural tissue, numerous cells and subcellular structures appear within a single image, they exhibit irregular shapes that cannot be easily modeled by standard techniques, and confusing textures clutter the background. We propose a fully automated approach that handles these challenges by using sophisticated cues that capture global shape and texture information, and by learning the specific appearance of object boundaries. We demonstrate that our approach significantly outperforms state-of-the-art techniques and closely matches the performance of human annotators. PMID:20879348

Lucchi, Aurélien; Smith, Kevin; Achanta, Radhakrishna; Lepetit, Vincent; Fua, Pascal



REX-ISOLDE RFQ Beam Dynamics Studies using CST EM Studio  

E-print Network

The original CNC milling files used to machine the electrodes of the REX-ISOLDE RFQ were acquired in late 2012 and electrostatic simulations were carried out using CST EM Studio in order to attain a 3D field map of the electric fields in the region around the beam axis. The objective was to construct a beam dynamics simulation tool that frees us from the constraints of the PARMTEQM code, which was used to design the RFQ, and that will afford us more flexibility in the studies needed for pre-bunching into the RFQ with an external multi-harmonic buncher. This note details the geometry of the electrodes and their simulation in CST EM Studio, the implementation of particle tracking in the computed field map using TRACK and benchmarking studies with PARMTEQM v3.09.

Fraser, M A



Speech Articulator and User Gesture Measurements Using Micropower, Interferometric EM-Sensore  

SciTech Connect

Very low power, GHz frequency, ''radar-like'' sensors can measure a variety of motions produced by a human user of machine interface devices. These data can be obtained ''at a distance'' and can measure ''hidden'' structures. Measurements range from acoustic induced 10-micron amplitude vibrations of vocal tract tissues, to few centimeter human speech articulator motions, to meter-class motions of the head, hands, or entire body. These EM sensors measure ''fringe motions' as reflected EM waves are mixed with a local (homodyne) reference wave. These data, when processed using models of the system being measured, provide real time states of interface positions vs. time. An example is speech articulator positions vs. time in the user's body. This information appears to be useful for a surprisingly wide range of applications ranging from speech coding and recognition, speaker or object identification, noise cancellation, hand or head motions for cursor direction, and other applications.

Holzrichter, J.F.



Speech Articulator and User Gesture Measurements Using Micropower, Interferometric EM-Sensors  

SciTech Connect

Very low power, GHz frequency, ''radar-like'' sensors can measure a variety of motions produced by a human user of machine interface devices. These data can be obtained ''at a distance'' and can measure ''hidden'' structures. Measurements range from acoustic induced, 10-micron amplitude vibrations of vocal tract tissues, to few centimeter human speech articulator motions, to meter-class motions of the head, hands, or entire body. These EM sensors measure ''fringe motions'' as reflected EM waves are mixed with a local (homodyne) reference wave. These data, when processed using models of the system being measured, provide real time states of interface positions or other targets vs. time. An example is speech articulator positions vs. time in the user's body. This information appears to be useful for a surprisingly wide range of applications ranging from speech coding synthesis and recognition, speaker or object identification, noise cancellation, hand or head motions for cursor direction, and other applications.

Holzrichter, J F; Ng, L C



Use of the AIC with the EM algorithm: A demonstration of a probability model selection technique  

SciTech Connect

The problem of discriminating between two potential probability models, a Gaussian distribution and a mixture of Gaussian distributions, is considered. The focus of interest is a case where the models are potentially non-nested and the parameters of the mixture model are estimated through the EM algorithm. The AIC, which is frequently used as a criterion for discriminating between non-nested models, is modified to work with the EM algorithm and is shown to provide a model selection tool for this situation. A particular problem involving an infinite mixture distribution known as Middleton`s Class A model is used to demonstrate the effectiveness and limitations of this method. The problem involves a probability model for underwater noise due to distant shipping.

Glosup, J.G.; Axelrod, M.C.



Statistical analysis of the influence of forces on particles in EM driven recirculated turbulent flows  

NASA Astrophysics Data System (ADS)

The present paper contains an analysis of the statistical distribution of forces affecting non-conducting particles dispersed in an EM induced recirculated flow in induction furnaces. The simulation is conducted adopting the LES-based Euler-Lagrange approach in the limit of dilute conditions (one-way coupling). It is done by means of a development of OpenFOAM software code. The used Lagrange equation for particle tracking includes drag, EM, buoyancy, lift, acceleration and added mass forces. The relevant approximations for the forces are chosen on the basis of the statistical analysis of the non-dimensional parameters (particle Reynolds number, shear stress and acceleration parameter). The effect of force distribution on particle homogenization is described under different density ratios and particle sizes. The recommendations of the consistence of the Lagrange model for the simulation of the particle motion in the laboratory scale induction crucible furnace are given in conclusion.

Š?epanskis, M.; Jakovi?s, A.; Baake, E.



Propagac ~ao acustica em aguas profundas na presenca de massas d'aguas de mesoescala na costa sudoeste de Portugal  

E-print Network

Propagac¸ ~ao ac´ustica em ´aguas profundas na presenc¸a de massas d'´aguas de mesoescala na costa trabalho baseia-se no estudo da propagac¸ ~ao sonora em ´aguas oce^anicas profundas na costa Portuguesa massa d'´agua de mesosescala. Mostraremos que tal massa d'´agua d´a origem `a um acoplamento entre dois

Jesus, Sérgio M.


Integration of CC®, IAQ, and EM for an Optimum and Proactive Energy Performance at Alamo Colleges, San Antonio, Texas.  

E-print Network

1 Integration of CC?, IAQ, and EM for an Optimum and Proactive Energy Performance at Alamo Colleges, San Antonio, Texas. Norma L. Rangel, Stephen O?Neal, and Joseph T. Martinez; Energy Systems Laboratory John W. Strybos Alamo Colleges Energy... Agency of the State of Texas Integration of CC?, IAQ, and EM for an Optimum and Proactive Energy Performance at Alamo Colleges, Texas Outline Alamo?Colleges,?San?Antonio,?TX. Continuous?Commissioning??Measures Indoor?Air?Quality?Efforts Energy...

Rangel, N.; O'Neal, S.; Martinez, J.; Strybos, J.



Estudo etnobotânico em duas comunidades rurais (Limeira e Ribeirão Grande) de Guaratuba (Paraná, Brasil)  

Microsoft Academic Search

RESUMO: Realizou-se levantamento etnobotânico em duas comunidades rurais etnicamente distintas (Limeira e Ribeirão Grande) de Guaratuba (Paraná, Brasil) para identificar plantas utilizadas na terapêutica popular, utilizando-se entrevistas semi-estruturadas (n= 11 e n= 7, respectivamente). Além de informações sócio-econômicas sobre a população amostrada, as seguintes informações sobre o uso de plantas medicinais foram registradas: nome popular, indicação terapêutica, parte usada, modo


Sector collapse at Kick 'em Jenny submarine volcano (Lesser Antilles): numerical simulation and landslide behaviour  

NASA Astrophysics Data System (ADS)

Kick 'em Jenny volcano is the only known active submarine volcano in the Lesser Antilles. It lies within a horseshoe-shaped structure open to the west northwest, toward the deep Grenada Basin. A detailed bathymetric survey of the basin slope at Kick 'em Jenny and resulting high-resolution digital elevation model allowed the identification of a major submarine landslide deposit. This deposit is thought to result from a single sector collapse event at Kick 'em Jenny and to be linked to the formation of the horseshoe-shaped structure. We estimated the volume and the leading-edge runout of the landslide to be ca. 4.4 km3 and 14 km, respectively. We modelled a sector collapse event of a proto Kick 'em Jenny volcano using VolcFlow, a finite difference code based on depth-integrated mass and momentum equations. Our models show that the landslide can be simulated by either a Coulomb-type rheology with low basal friction angles (5.5°-6.5°) and a significant internal friction angle (above 17.5°) or, with better results, by a Bingham rheology with low Bingham kinematic viscosity (0 < ? B < 30 m2/s) and high shear strength (130 < ? ? 180 m2/s2). The models and the short runout distance suggest that the landslide travelled as a stiff cohesive flow affected by minimal granular disaggregation and slumping on a non-lubricated surface. The main submarine landslide deposit can therefore be considered as a submarine mass slide deposit that behaved like a slump.

Dondin, Frédéric; Lebrun, Jean-Frédéric; Kelfoun, Karim; Fournier, Nicolas; Randrianasolo, Auran



Comportamento da Fundao de um Prottipo de Estrutura de Conteno em Solo Reforado com Geotxtil Notecido  

E-print Network

Comportamento da Fundação de um Protótipo de Estrutura de Contenção em Solo Reforçado com Geotêxtil comportamento de estruturas reforçadas com geotêxtil, foi construído um protótipo de estrutura de contenção, com utilizando a técnica de solo envelopado. Visando garantir um comportamento de deformação plana, a geometria

Zornberg, Jorge G.


Model Selection Criteria for Missing-Data Problems Using the EM Algorithm  

PubMed Central

We consider novel methods for the computation of model selection criteria in missing-data problems based on the output of the EM algorithm. The methodology is very general and can be applied to numerous situations involving incomplete data within an EM framework, from covariates missing at random in arbitrary regression models to nonignorably missing longitudinal responses and/or covariates. Toward this goal, we develop a class of information criteria for missing-data problems, called ICH,Q, which yields the Akaike information criterion and the Bayesian information criterion as special cases. The computation of ICH,Q requires an analytic approximation to a complicated function, called the H-function, along with output from the EM algorithm used in obtaining maximum likelihood estimates. The approximation to the H-function leads to a large class of information criteria, called ICH?(k),Q. Theoretical properties of ICH?(k),Q, including consistency, are investigated in detail. To eliminate the analytic approximation to the H-function, a computationally simpler approximation to ICH,Q, called ICQ, is proposed, the computation of which depends solely on the Q-function of the EM algorithm. Advantages and disadvantages of ICH?(k),Q and ICQ are discussed and examined in detail in the context of missing-data problems. Extensive simulations are given to demonstrate the methodology and examine the small-sample and large-sample performance of ICH?(k),Q and ICQ in missing-data problems. An AIDS data set also is presented to illustrate the proposed methodology. PMID:19693282

Ibrahim, Joseph G.; Zhu, Hongtu; Tang, Niansheng



Premissas histórico-socioculturais sobre a família brasileira em função do sexo e da idade  

Microsoft Academic Search

Resumo Segundo a abordagem etnopsicológica, as premissas histórico-socioculturais, que constituem crenças inquestionáveis consensualmente aceitas por um grupo social, desempenham papel chave na compreensão do comportamento individual. Apoiando-se nessa perspectiva, investigou-se a influência do sexo e idade no grau de adesão a premissas sobre a família brasileira. A amostra compreendeu 393 sujeitos de ambos os sexos, distribuídos em quatro faixas etárias,

Eveline Maria Leal Assmar; Maria Cristina Ferreira; Heliane Novaes; Mariana Tomaz



Support Vector Machines in the Machine Learning Classifier for a Texas Hold'em Poker Bot  

Microsoft Academic Search

This design project explores a fascinating application of artificial intelligence and machine learning to one of today's most popular mental challenges: Texas Hold'em poker. Recently, IBM's Deep Blue computer chess program managed to defeat the grandmaster Gary Kasparov utilizing an advanced brute-force search—a method dependent upon chess being a game of deterministic perfect information. This technique cannot be applied to

Jeremy Pfund


Multi-class brain segmentation using atlas propagation and EM-based refinement  

Microsoft Academic Search

In recent years, multi-atlas segmentation has emerged as one of the most accurate techniques for the segmentation of brain magnetic resonance (MR) images, especially when combined with intensity-based refinement techniques such as graph-cut or expectation-maximization (EM) optimization. However, most of the work so far has focused on intensity-based refinement strategies for individual anatomical structures such as the hippocampus. In this

Christian Ledig; Robin Wolz; Paul Aljabar; Jyrki Lotjonen; Rolf A. Heckemann; Alexander Hammers; Daniel Rueckert



Noise and Resolution Properties of FB and Ml-Em Reconstructed Spect Images.  

NASA Astrophysics Data System (ADS)

The purpose of this study was to quantify the quality of SPECT images reconstructed using the filtered -backprojection (FB) and maximum likelihood-expectation maximum (ML-EM) algorithms. We did this by investigating what we considered to be the fundamental components of medical image quality-resolution and noise. We studied resolution using the point response function (PRF) in the spatial domain and the modulation transfer function (MTF) in the frequency domain. The noise was investigated in terms of the covariance function (C) in the spatial domain and the noise power spectrum (NPS) in the frequency domain. For linear FB the techniques used to calculate the C and NPS involved a straightforward manipulation of the reconstruction transfer function. For non-linear ML-EM, both analytical and Monte Carlo methods were employed to calculate the noise properties. The method for measuring the PRF for FB reconstructed images was similar to the method for calculating C. To compute the PRF for ML-EM we assumed linearity for low-contrast perturbations. We tested these computational methods during the course of the study. To account for the non-stationarity of SPECT images we defined all of the terms locally. We studied FB as a function of filter cutoff for a Butterworth noise apodization filter and as a function of order for a Metz filter designed to compensate for detector response and scatter. We studied ML-EM as a function of iteration stopping point and as a function of the projector used in the algorithm. The projectors we examine accounted for some or all of the effects of geometric response, scatter, and attenuation. We tested image properties for different diagnostic situations, using three different phantoms. The image property measures were used, in many of these imaging situations, to draw inferences on image quality and to suggest optimal reconstruction algorithms and reconstruction parameters.

Wilson, Donald William


Impact of nitrogen reduction measures on the nitrogen loads of the river Ems and Rhine (Germany)  

Microsoft Academic Search

The REGFLUD-project, commissioned by Germany’s Federal Research Ministry (BMBF), addresses the problem of reducing diffuse pollution from agricultural production. The objective of the project is the development and application of multi-criteria scientific methods, which are able to predict diffuse pollution in river basins subject to economic feasibility and social acceptability. The selected river basins (the entire Ems basin and sub-catchments

F. Wendland; H. Bogena; H. Goemann; J. F. Hake; P. Kreins; R. Kunkel



Em 2053 teremos desvendado todos os mistrios do crebro? Conseguiremos conhe-  

E-print Network

dos projetos internacionais que es- tão a ser desenvolvidos em território nacional. Energia solar de cento da energia que ire mos utilizar será solar. Coisas como novos com- bustíveis, dessalinização da absor- ção de energia solar a partir dessa espécie de lupas gigantes que são os concentradores de al

Instituto de Sistemas e Robotica


List-mode likelihood: EM algorithm and image quality estimation demonstrated on 2-D PET  

Microsoft Academic Search

Using a theory of list-mode maximum-likelihood (ML) source reconstruction presented recently by Barrett et al. (1997), this paper formulates a corresponding expectation-maximization (EM) algorithm, as well as a method for estimating noise properties at the ML estimate. List-mode ML is of interest in cases where the dimensionality of the measurement space impedes a binning of the measurement data. It can

Lucas Parra; Harrison H. Barrett



The microtubule binding drug EM011 inhibits the growth of paediatric low grade gliomas.  


Low grade gliomas are a heterogeneous group of tumours representing the most common form of neoplasms in the central nervous system among children. Although gross total resection remains the principal treatment, it is often impractical especially for the resection of tumours within eloquent regions of the brain. Instead Radiotherapy is utilised in such cases, but because of its associated toxicities, it is refrained from use among younger children. These limitations coupled with hypersensitivity and toxicities associated with some commonly used chemotherapeutic agents, have ignited the need to search for safer and more effective treatments for paediatric low grade gliomas. In this study, we investigated the EM011 drug on the growth of two pilocytic and one diffuse paediatric astrocytoma cell lines, using an assortment of cancer assays. We discovered that treatments of low grade gliomas with EM011 abrogated cell viability by inducing a decrease in cell proliferation and an arrest in the S and G2M cell cycle phases, followed by a converse increase in apoptosis in a dose and time dependent manner. The cell migratory and invasion indices, as well as anchorage independent growth in soft agarose, were significantly attenuated. These findings were mechanistically associated with a transient release of AIF, a disruption of microtubule architecture, and a decline in the expression of key genes which drive cancer progression including EGFR, mTORC1, JUN and multiple MMPs. In fact, the activity of MMP2 was also perturbed by EM011. These findings, in conjunction with the insignificant adverse side effects established from other studies, make EM011 an appealing chemotherapeutic agent for the treatment of paediatric low grade gliomas. PMID:23402815

Ajeawung, Norbert F; Joshi, Harish C; Kamnasaran, Deepak



A generalized EM algorithm for 3-D Bayesian reconstruction from Poisson data using Gibbs priors  

Microsoft Academic Search

A generalized expectation-maximization (GEM) algorithm is developed for Bayesian reconstruction, based on locally correlated Markov random-field priors in the form of Gibbs functions and on the Poisson data model. For the M-step of the algorithm, a form of coordinate gradient ascent is derived. The algorithm reduces to the EM maximum-likelihood algorithm as the Markov random-field prior tends towards a uniform

T. Hebert; R. Leahy



Design, construction and performance of an EMS-based HTS maglev vehicle  

Microsoft Academic Search

A laboratory-scale EMS-based HTS maglev vehicle operating over a 1.5m guideway has been successfully constructed. The fully integrated system consists of a vehicle chassis, four dependent magnetic circuits, four distance sensors, and control and power amplification circuits. As key component of the system, each magnetic circuit includes a U-shape iron core with one HTS coil forming each pole. Eight HTS

Chen Gu; Menglin Liu; Huawei Xing; Tong Zhou; Wensheng Yin; Jun Zong; Zhenghe Han



A Memory-Based Approach to Two-Player Texas Hold'em  

Microsoft Academic Search

A Case-Based Reasoning system, nicknamed SARTRE, that uses a memory-based approach to play two-player, limit Texas Hold’em is introduced. SARTRE records hand histories from strong players and attempts to re-use this information to handle novel situations. SARTRE’S case features and their representations are described, followed by the results obtained when challenging a world-class computerised\\u000a opponent. Our experimental methodology attempts to

Jonathan Rubin; Ian Watson



Spike models for sputtering: Eect of the surface and the material E.M. Bringa a  

E-print Network

of Virginia, Thornton Hall, Charlottesville, VA 22903-2442, USA b Departamento de Fõsica Fundamental * Corresponding author. Tel.: +1-804-982-2335; fax: +1-804- 924-1353. E-mail addresses: (E.M. Bringa), (R.E. Johnson). 0168-583X/00/$ - see front matter � 2000 Elsevier Science B

Johnson, Robert E.



E-print Network

MODELAGEM DE CHEGADAS EM FILAS GI[X]/M/C/K VIA N�CLEO-ESTIMADORES F. R. B. Cruz, A. R. Duarte, N. L A incorporação da estimação estatística na análise de filas finitas é uma ideia interessante e promissora como tamanho do sistema. Os resultados são animadores. Palavras-Chave: estatística, sistemas de filas, núcleo

Cruz, Frederico


Statistical analysis of the influence of forces on particles in EM driven recirculated turbulent flows  

Microsoft Academic Search

The present paper contains an analysis of the statistical distribution of forces affecting non-conducting particles dispersed in an EM induced recirculated flow in induction furnaces. The simulation is conducted adopting the LES-based Euler-Lagrange approach in the limit of dilute conditions (one-way coupling). It is done by means of a development of OpenFOAM software code. The used Lagrange equation for particle

M Š?epanskis; A Jakovi?s; E Baake



Un algorithme EM recursif pour le SLAM Sylvain LE CORFF,Gersende FORT,Eric MOULINES  

E-print Network

Un algorithme EM r´ecursif pour le SLAM Sylvain LE CORFF,Gersende FORT,Eric MOULINES LTCI, TELECOM Simultan´ees (SLAM) lorsque les mod`eles d'´etat et d'observations sont non lin´eaires et non gaussiens contribution `a la r´esolution du SLAM r´eside `a la fois (i) dans la formulation du probl`eme de cartographie

Fort, Gersende


Application of Fuzzy Logic to EMS-type Magnetically Levitated Railway Vehicle  

NASA Astrophysics Data System (ADS)

A type of the magnetically levitated railway system with the electro-magnetic suspension system (EMS), which is named HSST system, will be put into revenue service as an urban transport in Nagoya, Japan at the beginning of April 2005. To extend its operational velocity higher than 200km/h for applications in other cities, the design of its EMS system is reexamined for improvement of riding comfort and performances of a train. In order to achieve these objectives, the multipurpose optimization on the basis of the genetic algorithm is applied for the design of EMS-type magnetically levitated vehicle, control parameters of which are optimized both to follow the rail exactly in high-speed and to provide enough riding comfort to passengers. However, the ability to follow sharp irregularities of the rail and to cope with high frequency noises in the gap length control system should be coordinated with riding comfort. The fuzzy logic is introduced into the dynamic control loop and verified to solve the problem. Far better coordination is obtained between the vehicle performances and riding comfort of passengers in high-speed against such various rail conditions. The levitation control with fuzzy logic is shown to be useful for the critical design problem as the high-speed maglev railways.

Kusagawa, Shinichi; Baba, Jumpei; Shutoh, Katsuhiko; Masada, Eisuke


The Evolution of the EM Distribution in the Core of an Active Region  

E-print Network

We study the spatial distribution and evolution of the slope of the Emission Measure between 1 and 3~MK in the core active region NOAA~11193, first when it appeared near the central meridian and then again when it re-appeared after a solar rotation. We use observations recorded by the Extreme-ultraviolet Imaging Spectrometer (EIS) aboard Hinode, with a new radiometric calibration. We also use observations from the Atmospheric Imaging Assembly (AIA) aboard Solar Dynamics Observatory (SDO). We present the first spatially resolved maps of the EM slope in the 1--3~MK range within the core of the AR using several methods, both approximate and from the Differential Emission Measure (DEM). A significant variation of the slope is found at different spatial locations within the active region. We selected two regions that were not affected too much by any line-of-sight lower temperature emission. We found that the EM had a power law of the form EM~$\\propto T^{b}$, with b = 4.4$\\pm0.4$, and 4.6$\\pm0.4$, during the first...

Del Zanna, Giulio; Mason, Helen; Subramanian, Srividya; O'Dwyer, Brendan



Helicopter-borne measurements of sea ice thickness, using a small and lightweight, digital EM system  

NASA Astrophysics Data System (ADS)

Sea ice is an important climate variable and is also an obstacle for marine operations in polar regions. We have developed a small and lightweight, digitally operated frequency-domain electromagnetic-induction (EM) system, a so-called EM bird, dedicated for measurements of sea ice thickness. It is 3.5 m long and weighs only 105 kg, and can therefore easily be shipped to remote places and operated from icebreakers and small helicopters. Here, we describe the technical design of the bird operating at two frequencies of f1 = 3.68 kHz and f2 = 112 kHz, and study its technical performance. On average, noise amounts to ± 8.5 ppm and ± 17.5 ppm for f1 and f2, respectively. Electrical drift amounts to 200 ppm/h and 2000 ppm/h for f1 and f2, during the first 0.5 h of operation. It is reduced by 75% after 2 h. Calibration of the Inphase and Quadrature ppm signals varies by 2 to 3%. A sensitivity study shows that all these signal variations do affect the accuracy of the ice thickness retrieval, but that it remains better than ± 0.1 m over level ice in most cases. This accuracy is also confirmed by means of comparisons of the helicopter EM data with other thickness measurements. The paper also presents the ice thickness retrieval from single-component Inphase data of f1.

Haas, Christian; Lobach, John; Hendricks, Stefan; Rabenstein, Lasse; Pfaffling, Andreas



A GL Double Layer EM Cloaks In Broad Frequency Band And Reciprocal Law  

E-print Network

In this paper, we propose a novel GLWF double layer EM cloak in the broad frequency band. The GLWF double layer cloak consists of two sphere annular layers, two type cloak materials are proposed and installed in its each layer, respectively. The outer layer of the GL cloak has the invisible function in broad frequency band, while its inner layer has the fully absorption and rapid delay function. The GLWF double layer cloak overcomes the following difficulties of the single layer PS cloak. (1) There exists no EM wavefield can be excited inside the concealment of the PS cloak, the concealment of the PS cloak is blind. Our GL double layer cloak recovered that the EM wave field can be excited inside the concealment of the GL double layer cloak. (2) There is exceeding light speed physical violation in PS cloak, its invisibility only in very narrow frequency band. Our GLWF double layer cloak corrects the violation. (3) The reciprocal law is satisfied in our GL double cloak media. However, the PS cloak damaged the r...

Xie, Ganquan; Xie, Lee; Xie, Feng



Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles  

PubMed Central

Although electron cryo-microscopy (cryo-EM) single-particle analysis has become an important tool for structural biology of large and flexible macro-molecular assemblies, the technique has not yet reached its full potential. Besides fundamental limits imposed by radiation damage, poor detectors and beam-induced sample movement have been shown to degrade attainable resolutions. A new generation of direct electron detectors may ameliorate both effects. Apart from exhibiting improved signal-to-noise performance, these cameras are also fast enough to follow particle movements during electron irradiation. Here, we assess the potentials of this technology for cryo-EM structure determination. Using a newly developed statistical movie processing approach to compensate for beam-induced movement, we show that ribosome reconstructions with unprecedented resolutions may be calculated from almost two orders of magnitude fewer particles than used previously. Therefore, this methodology may expand the scope of high-resolution cryo-EM to a broad range of biological specimens. DOI: PMID:23427024

Bai, Xiao-chen; Fernandez, Israel S; McMullan, Greg; Scheres, Sjors HW



Profiling the Local Seebeck Coefficient with Nanometer Resolution Using Scanning Thermoelectric Microscopy (SThEM)  

NASA Astrophysics Data System (ADS)

Thermoelectric (TE) devices offer a method of recovering waste heat through solid state conversion of heat to electricity. Nanostructured thermoelectric materials may provide the key to increased efficiencies, which are sensitive to the Seebeck coefficients (S) However, traditional bulk measurement techniques can only provide a spatially averaged measurement of S over the whole sample, which can hardly investigate the effects of nanostructures on S on the nanoscale. A novel technique known as scanning thermoelectric microscopy (SThEM) has recently been developed to measure induced thermal voltages with nanometer resolution In SThEM, an unheated scanning tunneling microscopy tip acts as a high-resolution voltmeter probe to measure the thermally-induced voltage, V, in a heated sample. Here we present a local S measurement using SThEM across an InGaAs P-N junction. The thermovoltage shows an abrupt change of sign within 10 nanometers, which reveals nanometer spatial resolution. We will discuss local S measurements of AlAs/GaAs superlattices (SLs) with various SL periods and compare the local S with scanning tunneling spectroscopy measurements, which will reveal how local electronic states influence thermoelectric properties.

Lin, Yen-Hsiang; Walrath, Jenna; Goldman, Rachel



Direct electron detection yields cryo-EM reconstructions at resolutions beyond 3/4 Nyquist frequency  

PubMed Central

One limitation in electron cryo-microscopy (cryo-EM) is the inability to recover high-resolution signal from the image-recording media at the full-resolution limit of the transmission electron microscope. Direct electron detection using CMOS-based sensors for digitally recording images has the potential to alleviate this shortcoming. Here, we report a practical performance evaluation of a Direct Detection Device (DDD) for biological cryo-EM at two different microscope voltages: 200 and 300 kV. Our DDD images of amorphous and graphitized carbon show strong per-pixel contrast with image resolution near the theoretical sampling limit of the data. Single-particle reconstructions of two frozen-hydrated bacteriophages, P22 and ?15, establish that the DDD is capable of recording usable signal for 3-D reconstructions at about 4/5 of the Nyquist frequency, which is a vast improvement over the performance of conventional imaging media. We anticipate the unparalleled performance of this digital recording device will dramatically benefit cryo-EM for routine tomographic and single-particle structural determination of biological specimens. PMID:22285189

Bammes, Benjamin E.; Rochat, Ryan H.; Jakana, Joanita; Chen, Dong-Hua; Chiu, Wah



Reaching the information limit in cryo-EM of biological macromolecules: experimental aspects.  


Although cryo-electron microscopy (cryo-EM) of biological macromolecules has made important advances in the past few years, the level of current technical performance is still well below what the physics of electron scattering would allow. It should be possible, for example, to use cryo-EM to solve protein structures at atomic resolution for particle sizes well below 80 kDa, but currently this has been achieved only for particles at least 10 times larger than that. In this review, we first examine some of the reasons for this large gap in performance. We then give an overview of work that is currently in progress to 1), improve the signal/noise ratio for area detectors; 2), improve the signal transfer between the scattered electrons and the corresponding images; and 3), reduce the extent to which beam-induced movement causes a steep fall-off of signal at high resolution. In each case, there is substantial reason to think that cryo-EM can indeed be made to approach the estimated physical limits. PMID:21575566

Glaeser, Robert M; Hall, Richard J



Cryo-EM Imaging of DNA-PK DNA Damage Repair Complexes  

SciTech Connect

Exposure to low levels of ionizing radiation causes DNA double-strand breaks (DSBs) that must be repaired for cell survival. Higher eukaryotes respond to DSBs by arresting the cell cycle, presumably to repair the DNA lesions before cell division. In mammalian cells, the nonhomologous end-joining DSB repair pathway is mediated by the 470 kDa DNA-dependent protein kinase catalytic subunit (DNA-PKcs) together with the DNA-binding factors Ku70 and Ku80. Mouse knock-out models of these three proteins are all exquisitely sensitive to low doses of ionizing radiation. In the presence of DNA ends, Ku binds to the DNA and then recruits DNA-PKcs. After formation of the complex, the kinase activity associated with DNA-PKcs becomes activated. This kinase activity has been shown to be essential for repairing DNA DSBs in vivo since expression of a kinase-dead form of DNA-PKcs in a mammalian cell line that lacks DNA-PKcs fails to complement the radiosensitive phenotype. The immense size of DNA-PKcs suggests that it may also serve as a docking site for other DNA repair proteins. Since the assembly of the DNA-PK complex onto DNA is a prerequisite for DSB repair, it is critical to obtain structural information on the complex. Cryo-electron microscopy (cryo-EM) and single particle reconstruction methods provide a powerful way to image large macromolecular assemblies at near atomic (10-15 ?) resolution. We have already used cryo-EM methods to examine the structure of the isolated DNA-PKcs protein. This structure reveals numerous cavities throughout the protein that may allow passage of single or double-stranded DNA. Pseudo two-fold symmetry was found for the monomeric protein, suggesting that DNA-PKcs may interact with two DNA ends or two Ku heterodimers simultaneously. Here we propose to study the structure of the cross-linked DNA-PKcs/Ku/DNA complex. Difference imaging with our published DNA-PKcs structure will enable us to elucidate the architecture of the complex. A second objective is to locate the kinase domain of DNA-PKcs by determining the structure of a kinase deletion mutant both as an isolated protein and as part of a DNA-PKcs/Ku/DNA complex. A third objective is to pursue higher resolution studies of DNA-PKcs and the DNA-PKcs/Ku/DNA complex. If the crystal structure determination of DNA-PKcs is completed during the project period, the atomic coordinates of DNA-PKcs will be modeled within the cryo-EM structure of the complex. In order to achieve these goals, a collaborative effort is proposed between Dr. Phoebe Stewart at UCLA, whose laboratory has expertise in cryo-EM reconstruction methods, and Dr. David Chen at the Lawrence Berkeley National Laboratory, who has a long-standing interest in DNA repair. Advantages of the cryo-EM structural method include the fact that the sample is imaged in a frozen-hydrated and unstained state, avoiding artifacts associated with drying and staining i