Sample records for radiodiagnostico clinico con

  1. [6-unit clinico-physical complex].

    PubMed

    Dzhelepov, V P; Savchenko, O V; Astrakhan, B V; Ruderman, A I

    1987-08-01

    The article is devoted to the results of application of high energy proton beams, negative pi-mesons and neutrons in biomedical and clinical investigations carried out at the 680 MeV phasotron (the JINR Laboratory of Nuclear Problems) before its conversion. A six-compartment clinico-physical facility is described. It has been constructed at the converted phasotron in order to continue and expand investigations for application of heavy nuclear particles in radiation therapy. The first physical and dosimetric characteristics of medical proton beams produced in the converted accelerator and guided to chambers 1 and 2 of the new clinico-physical facility are discussed. The future of radiobiological and clinical investigations with high energy proton, negative pion and neutron beams of this facility is also discussed. PMID:3041168

  2. [Clinico-roentgenological semiotics of the chest damage in polytrauma].

    PubMed

    Zamiatin, P N; Panchenko, E V; Grigor'ian, G O; Goloshchapova, E V

    2006-10-01

    There are presented the main clinico-roentgenological signs of the chest damage in the injured persons, suffering polytrauma, according to the data from the specialized department of traumatic shock and polytrauma. PMID:17269409

  3. Clinico-pathological features and survival of lung cancer patients in Paris, France

    Microsoft Academic Search

    J. Trédaniel; P. Boffetta; C. Chastang; A. Hirsch

    1995-01-01

    We studied the clinico-pathological features of 750 lung cancers identified in Paris, France, during 1988. An internal comparison was performed between adenocarcinomas and other subtypes. Survival of 502 patients was studied. 85% of patients were males; 93% were smokers or ex-smokers. Squamous cell carcinomas, adenocarcinomas, small cell carcinomas and large cell cancers accounted for 51, 22, 15 and 12% of

  4. Clinico-pathological features and survival of lung cancer patients in Paris, France.

    PubMed

    Trédaniel, J; Boffetta, P; Chastang, C; Hirsch, A

    1995-12-01

    We studied the clinico-pathological features of 750 lung cancers identified in Paris, France, during 1988. An internal comparison was performed between adenocarcinomas and other subtypes. Survival of 502 patients was studied. 85% of patients were males; 93% were smokers or ex-smokers. Squamous cell carcinomas, adenocarcinomas, small cell carcinomas and large cell cancers accounted for 51, 22, 15 and 12% of all cases, respectively. Differences were found for the distribution of histological subtyping according to sex (P = 0.001) and smoking status (P = 0.0001) with a greater proportion of adenocarcinomas for women and non-smokers. Median overall survival was less than one year. In multiple regression analysis, small cell lung cancer patients appeared to have a worse prognosis than other histological subtypes. This study describes patients who were treated in community practice and might be more representative of the real clinico-pathological profile of this disease in France. PMID:8652259

  5. Clinico-etiological study of 30 erythroderma cases from tertiary center in South India

    PubMed Central

    Hulmani, Manjunath; NandaKishore, B.; Bhat, M. Ramesh; Sukumar, D.; Martis, Jacintha; Kamath, Ganesh; Srinath, M. K.

    2014-01-01

    Background: Erythroderma is a morphological reaction pattern of skin having many underlying causes and finding the etiology helps in the proper management of erythroderma cases. Aim: To evaluate the clinical profile, etiology of erythroderma and to correlate clinical diagnosis with histopathology. Materials and Methods: This study was performed at the department of dermatology, Father Muller Medical College and Hospital, Mangalore, South India. We studied 30 consecutive cases of erythroderma with respect to the epidemiological, clinical and histological data. Clinico-histological correlation was analyzed for etiology of erythroderma. Results: The mean age of onset was 52.3 years with a male to female ratio of 14:1. In addition to erythroderma, other co-existent features included pruritus, fever, lymphadenopathy, and edema. Of the pre-existing dermatoses, psoriasis was the most common (33.3%) disease followed by eczema (20%), atopic dermatitis (6.6%), pityriasis rubra pilaris (3.3%) and drug-induced erythroderma (16.6%). In 16.6% of cases, etiology could not be ascertained. Clinico-histopathological correlation could be established in 73.3% of cases. Conclusion: Clinical features were identical irrespective of etiology. Detailed clinico-histopathological examination helps to establish the etiology of erythroderma. PMID:24616850

  6. [Formalization of clinico-topometric information in planning combined programmed gamma-therapy of endometrial cancer].

    PubMed

    Titova, V A; Pavlova, T G; Romanovich, A I

    1987-07-01

    The paper is concerned with the problems of obtaining clinico-diagnostic and topometric information and its preparation for further computer-assisted use. Topometric schemes were made in the frontal, sagittal, and a series of transversal planes which permit assessment of the nature of ionizing radiation energy distribution in the main projection area of normal organs involved in the irradiated zone as well as within the limits of extended targets on the basis of optimized computer-assisted total dose distribution at the level of the tumor center. A dosimetric plan is regarded as a normal one if it meets the requirements of quality at all studied levels. PMID:3613920

  7. [Cornea guttata and Fuchs' endothelial-epithelial dystrophy. Clinico-histologic study of 73 patients].

    PubMed

    Lisch, W; Buob, M; Steuhl, K P

    1991-02-01

    In a retrospective, clinico-histological study, 84 corneas from 73 patients with diagnosed Fuchs' dystrophy (FD) were examined after penetrating keratoplasty. Seven types of posterior corneal degeneration were found: six with diversely arranged and pronounced guttae and a thickened Descemet's membrane, and a seventh with no guttae in either eye. This last variant appeared histologically in only two patients. Whether it represents a different syndrome can only be speculated. Our study showed, however, that the frequency of cornea guttata (CG) in FD is statistically significant in all the histological variants. PMID:2041372

  8. [Clinico-economical efficacy of angiotensin converting enzyme inhibitors in patients with arterial hypertension and ischemic heart disease].

    PubMed

    Korennova, O Iu; Petrenko, A V; Petrenko, M A; Kurt-Kovalenko, E V; Turusheva, E A; Alekseeva, S V; Mashinskaia, L G; Shupina, M I; Osipova, E A

    2008-01-01

    We conducted comparative analysis of clinico-economical efficacy of angiotensin converting enzyme inhibitors as components of combination therapy of patients with arterial hypertension and ischemic heart disease. Clinical efficacy of fosinopril, moexipril, perindopril, and ramipril was comparable: in compared groups statistically significant lowering of arterial pressure was achieved by day 6 of treatment and this lowering persisted up to day 36 of therapy with ramipril. All studied drugs were well tolerated. Ramipril was notable for highest economical efficacy determined by the method of \\"minimization of expenditures\\". Technology of assessment of clinico-economical effectiveness of preparations from the same pharmacological group can be used in compilation of standards of drug therapy of various diseases, basing on which a physician administers a concrete drug to a concrete patient. PMID:18729835

  9. Mass spectrometry protein expression profiles in colorectal cancer tissue associated with clinico-pathological features of disease

    Microsoft Academic Search

    Christopher CL Liao; Nicholas Ward; Simon Marsh; Tan Arulampalam; John D Norton

    2010-01-01

    BACKGROUND: Studies of several tumour types have shown that expression profiling of cellular protein extracted from surgical tissue specimens by direct mass spectrometry analysis can accurately discriminate tumour from normal tissue and in some cases can sub-classify disease. We have evaluated the potential value of this approach to classify various clinico-pathological features in colorectal cancer by employing matrix-assisted laser desorption

  10. Application of Clinico-Radiologic-Pathologic Diagnosis of Diffuse Parenchymal Lung Diseases in Children in China

    PubMed Central

    Xu, Dan; Chen, Zhimin; Chen, Huizhong; Huang, Rongyan; Zhao, Shunying; Liu, Xiuyun; Zhou, Chunju; Peng, Yun; Yuan, Xinyu; Zou, Jizhen; Zhang, Hailing; Zhao, Deyu; Liu, Enmei; Zheng, Yuejie; Zhong, Lili; Lu, Min; Lu, Jirong; Nong, Guangmin

    2015-01-01

    Diffuse parenchymal lung diseases in children (chDPLD) or interstitial lung diseases in children (chILD) represent a heterogeneous group of respiratory disorders that are mostly chronic and associated with high morbidity and mortality. However, the incidence of chDPLD is so low that most pediatricians lack sufficient knowledge of chDPLD, especially in China. Based on the clinico- radiologic- pathologic (CRP) diagnosis, we tried to describe (1) the characteristics of chDPLD and (2) the ratio of each constituent of chDPLD in China. Data were evaluated, including clinical, radiographic, and pathologic results from lung biopsies. We collected 25 cases of chDPLD, 18 boys and 7 girls with a median age of 6.0 years, from 16 hospitals in China. The most common manifestations included cough (n = 24), dyspnea (n = 21), and fever (n = 4). There were three cases of exposure-related interstitial lung disease (ILD), three cases of systemic disease-associated ILD, nineteen cases of alveolar structure disorder-associated ILD, and no cases of ILD specific to infancy. Non-specific interstitial pneumonia (n = 9) was the two largest groups. Conclusion: Non-specific interstitial pneumonia is the main categories of chDPLD in China. Lung biopsy is always a crucial step in the final diagnosis. However, clinical and imaging studies should be carefully evaluated for their value in indicating a specific chDPLD. PMID:25569558

  11. Bayesian Weibull tree models for survival analysis of clinico-genomic data

    PubMed Central

    Clarke, Jennifer; West, Mike

    2008-01-01

    An important goal of research involving gene expression data for outcome prediction is to establish the ability of genomic data to define clinically relevant risk factors. Recent studies have demonstrated that microarray data can successfully cluster patients into low- and high-risk categories. However, the need exists for models which examine how genomic predictors interact with existing clinical factors and provide personalized outcome predictions. We have developed clinico-genomic tree models for survival outcomes which use recursive partitioning to subdivide the current data set into homogeneous subgroups of patients, each with a specific Weibull survival distribution. These trees can provide personalized predictive distributions of the probability of survival for individuals of interest. Our strategy is to fit multiple models; within each model we adopt a prior on the Weibull scale parameter and update this prior via Empirical Bayes whenever the sample is split at a given node. The decision to split is based on a Bayes factor criterion. The resulting trees are weighted according to their relative likelihood values and predictions are made by averaging over models. In a pilot study of survival in advanced stage ovarian cancer we demonstrate that clinical and genomic data are complementary sources of information relevant to survival, and we use the exploratory nature of the trees to identify potential genomic biomarkers worthy of further study. PMID:18618012

  12. Clinico-epidemiological profile of chronic suppurative otitis media patients attending a tertiary care hospital.

    PubMed

    Neogi, Rajarshi; Dan, Amit; Maity, Kuntal; Basak, Bijan; Basu, Deepjoy; Acharya, Moloy; Sengupta, Arunava; Biswas, Akhil Bandhu

    2011-05-01

    The cross-sectional study was conducted to assess the clinico-epidemiological profile, perceptions and clinical profile of the chronic suppurative otitis media (CSOM) patients in a tertiary care hospital. A pretested questionnaire was used containing open questions and the patients were assessed clinically. Most patients (31.2%) were from 0-10 years age group and were males (58.8%). Majority of them (96%) lived in "kuccha" houses/slums, 76.8% practised unhygienic ear pricking, 36.8% poured oil in their ears, 70.8% bathed in ponds/rivers, 52.8% had ear discharge for more than 1 year. Among the respondents, 17.2% knew that CSOM was contagious, 24% thought CSOM ran in family, 20% knew CSOM is preventable. There was low threat perception and long time to seek care. Patients mostly presented with earache, deafness and discharge, most had deafness and safe variety of CSOM. More than half had comorbidities. Most of the previous study findings corroborated with the present study. Here was a substantial delay between the onset and treatment seeking due to lack of awareness and low threat perception. Pain and complications were the triggers for care-seeking. Education about the disease, strengthening the frontline workers and good referral system are suggested. PMID:22187766

  13. Impact of clinico-radiological parameters on the outcome of treatment in brain tuberculosis

    PubMed Central

    Lone, Manzoor Ahmad; Ganie, Farooq Ahmad; Ramzan, Altaf Umar; Kelam, Mohd Arif; Khan, Abdul Quoom; Masratul-Gani

    2014-01-01

    Objectives: The Aim of this study was to evaluate the impact of clinico-radiological parameters on the outcome of the treatment in brain tuberculosis. Materials and Methods: This study was conducted in the Department of Neurosurgery and Neurology Skims Srinagar India for a period of two years from November 2009 to November 2011. A total of 61 patients presenting with brain tuberculosis admitted at skims during these two years were included in the study. Patients having clinical, laboratory and radiological findings suggestive of brain tuberculosis were included in the study. On correlating the CT characteristics-tuberculomas, basal exudates and hydrocephalus with sequelae at 6,12 and 18 months - focal deficit, cognitive impairment, and diplopia. Results: It was seen that basal exudates correlated with all the three neurological sequelae i.e.; with focal deficit (P = 0.001), cognitive impairment (P = 0.011), and diplopia (P = 0.021). Hydrocephalus correlated well with cognitive impairment (P = 0.031) and tuberculoma correlated with none of these clinical characteristics. Conclusion: We concluded that the mortality and neurologic sequelae were directly related to the clinical stage of disease at presentation. Correlating the CT characteristics we concluded that basal exudates correlated with all the three sequelae i.e.; with focal deficit, cognitive impairment, and diplopia. Hydrocephalous correlated well with cognitive impairment and tuberculoma correlated with none of these clinical characteristics. PMID:25126120

  14. Trifurcation of superficial brachial artery: a rare case with its clinico-embryological implications.

    PubMed

    Gupta, N; Anshu, A; Dada, R

    2014-01-01

    Literatures on vasculature of upper limbs are crammed with reports of distinctly deviant version of normally prevalent vessels having modified origins, altered branching and odd courses. A unique anatomical variation in vascular pattern was observed during routine dissection of right upper limb in gross anatomy laboratory, AIIMS, New Delhi, India. The brachial artery was placed superficial to median nerve in the arm and therefore it was called superficial brachial artery. In the cubital fossa, 2.8 cm distal to intercondylar line of elbow joint, this superficial brachial artery terminated by trifurcation into radial, common interosseous and ulnar branches. Strikingly the ulnar branch, after its origin ran superficially over the median nerve and epitrochlear superficial flexor group of muscles of forearm in succession for the initial third of its course in the forearm, consequently it was addressed as superficial ulnar artery. The existence of superficial brachial artery in place of normal brachial artery, its termination by trifurcation into radial, common interosseous and superficial ulnar arteries with remarkably different courses, leads to confusing disposition of structures in the arm, cubital fossa and in the forearm and collectively makes this myriad of anatomical variations even rarer. The clinico-embryological revelations for combination of these unconventional observations, apprises and guides the specialized medical personnel attempting blind and invasive procedures in brachium and ante-brachium. This case report depicts the anatomical perspective and clinical implications on confronting a rare variant vasculature architecture pattern of upper limb. PMID:25366943

  15. Clinico-epidemiological study of near-hanging cases - An investigation from Nepal.

    PubMed

    Atreya, Alok; Kanchan, Tanuj

    2015-07-01

    Hanging is one of the commonest methods of suicide. Epidemiological data of near-hanging patients from Nepal is limited. The present research from Nepal attempts to review the clinico-epidemiological profile of near-hanging patients. A retrospective review of case records was done for the near hanging patients admitted to a tertiary care teaching hospital in Nepal, between August 2012 and August 2014. Details regarding socio-demographic profile, circumstances of hanging, clinical details, and outcome etc. were obtained and examined. During the study period, 10 near hanging patients were admitted to the hospital. The majority of the patients were below 30 years. Mean age of the study group was 28.8 years. The GCS on arrival ranged between 5/15 and 15/15 with the mean GCS being 9.5/15. Hypoxic encephalopathy and cerebral edema were the only noted complications. None of the patient had a cervical spinal injury. All the patients survived the near hanging episode. The mean ICU and hospital stay were 3.9 days and 6.2 days respectively. Prompt resuscitation, active interventions and intensive care support favors a good prognosis. Psychiatric evaluation and support to the patients and their relatives is the key to preventing such attempts in future. PMID:26048494

  16. A Clinico-Pathological Study of Lichenoid Tissue Reactions-A Tertiary Care experience

    PubMed Central

    Kumar U, Mahesh; Yelikar, Balasaheb Ramling; Inamadar, Arun C; Umesh, Swaroopa; Singhal, Amrita; Kushtagi, Anirudha V

    2013-01-01

    Introduction: The aim of this article was to study the spectrum of clinico-histopathological lesions with an age and sex distribution in various lichenoid reactions of the skin. The spectrum of clinical diseases which is related to the lichenoid tissue reaction is wider. There is a recent increase in the relatively new subgroups of the lichenoid clinical picture. Material And Methods: This was a one and a half year prospective study which was conducted in the Dermatopathology Section of the Department of Pathology, from January 2011 to June 2012. All the patients who visited the Dermatology Outpatients/ Inpatients Department and presented with lichenoid tissue reactions were included in the study. The selected patients’ clinical findings were noted and their informed consents and an institutional ethical clearance were taken. Light microscopy was used for the histopathological diagnosis. The SPSS, version 14 software was used to analyze the data. Frequencies and percentages were used to describe the data. Results: During the study period, 107 cases were clinically diagnosed as lichenoid reactions, of which 84 cases were concordant on histopathology and 6 cases were diagnosed, solely based on the histology. So, a total of 90 cases were diagnosed histologically, of which 42 were of the Lichen planus type and 48 were lichenoid eruptions. Females were affected more commonly than the males. Conclusion: In our study, the lichenoid reactions were more common in children and the most common prototype was Lichen planus. So, we conclude that histopathology is a dependable tool for identifying the underlying cause in lichenoid reactions. PMID:23543246

  17. [Medico-genetic study of isolates in Uzbekistan. IV. Clinico-biochemical diagnosis of hereditary diseases].

    PubMed

    Kozlova, S I; Diachenko, S S; Khannanova, F K; Kuleshov, N P; Khodzhaeva, G K

    1976-01-01

    An exhaustive clinico-biochemical examination of the population of two kishlaks of the Samarkand Region, viz. Karakent (210 persons) and Ishan (248 persons) was carried out. The program of this examination permitted to exclude over 160 forms of hereditary pathology. A total of 45 persons affected with diseases belonging to 12 nosological forms were revealed in the course of the examination. Among the diseases observed only 5 are hereditary sensu stricto, viz. myoclonus-epilepsy, Bonevi-Ulrich's syndrome, imperfect osteogenesis, pigment choreoretinite and Down's syndrome, others belong to diseases with a pronounced hereditary predisposition. The main part of this group comprises neuro-psychic diseases, such as non-differentiated olygophreny (5.0%), epilepsy (1.3%), schizophreny; many of these cases have a familial character, particularly in Karakent. Besides the persons suffering from diseases, 20 heterozygous carriers of beta-thalassemia and 17 heterozygous carriers of G6PD-deficiency were discovered in the kishlaks examined. On the whole the frequency of the diseases revealed did not exceed the level in the general population. Despite the different degree of isolation of the kishlaks examined (Karakent is isolated on a religious basis, F = 0.0064; while Ishan is a desintagrated isolate, F = = 0.0014), no substantial differences between them in the distribution of pathological phenomena were observed. On the basis of the experience of this expedition recomendations are proposed concerning the origination and accomplishment of medico-genetic expeditions. A scheme is proposed for the performance of medico-genetic examination through several stages. The first stage in the composition of tentative maps of the distribution of hereditary diseases within a region on the basis of the information obtained from the medical personnel and from the examination of the documents of district and regional hospitals. Subsequently the primary information is specified, the regions to be examined are determined, as well as concrete tasks and the staff of the expedition. The conclusive stage is the medico-genetic examination proper, including clinical, biochemical, immunological and cytogenetic diagnoses of hereditary pathological phenomena. The place of the disposition is a village or a district hospital. More complicated laboratory studies should be performed on the basis of the institution by which the expedition is formed. The results obtained by such expeditions would be important for the investigation of the problems of genogeography, for the discovery of new forms of mutant alleles, for the investigation of the causes and the conditions of the formation of the definite populational structure, of clinical polymorphism of human hereditary diseases. PMID:135712

  18. CENTRO CLINICO DE CNCER DE STANFORD CARTA INFORMATIVA SOBRE LA CITA PARA PACIENTES NUEVOS

    E-print Network

    Bogyo, Matthew

    HEMATOLOGY Centro Clínico de Cáncer de Stanford Centro De Medicina Avanzada Fecha: 875 Blake Wilbur Drive/a _______________________________________, Tiene una cita programada con el Departamento de Hematology. Por favor vea la fecha y hora de su cita CÁNCER DE STANFORD CARTA INFORMATIVA SOBRE LA CITA PARA PACIENTES NUEVOS HEMATOLOGY La clínica Hematology

  19. An eight-year snapshot of geospatial cancer research (2002-2009): clinico-epidemiological and methodological findings and trends.

    PubMed

    Boulos, Dina N Kamel; Ghali, Ramy R; Ibrahim, Ezzeldin M; Boulos, Maged N Kamel; AbdelMalik, Philip

    2011-12-01

    Geographic information systems (GIS) offer a very rich toolbox of methods and technologies, and powerful research tools that extend far beyond the mere production of maps, making it possible to cross-link and study the complex interaction of disease data and factors originating from a wide range of disparate sources. Despite their potential indispensable role in cancer prevention and control programmes, GIS are underrepresented in specialised oncology literature. The latter has provided an impetus for the current review. The review provides an eight-year snapshot of geospatial cancer research in peer-reviewed literature (2002-2009), presenting the clinico-epidemiological and methodological findings and trends in the covered corpus (93 papers). The authors concluded that understanding the relationship between location and cancer/cancer care services can play a crucial role in disease control and prevention, and in better service planning, and appropriate resource utilisation. Nevertheless, there are still barriers that hinder the wide-scale adoption of GIS and related technologies in everyday oncology practice. PMID:20589539

  20. Rare and challenging extra-axial brain lesions: CT and MRI findings with clinico-radiological differential diagnosis and pathological correlation

    PubMed Central

    Demir, Mustafa Kemal; Yap?c?er, Özlem; Onat, Elif; Tokta?, Zafer Orkun; Akak?n, Ak?n; Urgun, Kamran; K?l?ç, Türker

    2014-01-01

    There are many kinds of extra-axial brain tumors and tumor-like lesions, and definitive diagnosis is complicated in some cases. In this pictorial essay, we present rare and challenging extra-axial brain lesions including neuroenteric cyst, primary leptomeningeal melanomatosis, isolated dural neurosarcoidosis, intradiploic epidermoid cyst, ruptured dermoid cyst, intraventricular cavernoma, and cavernous hemangioma of the skull with imaging findings and clinico-radiological differential diagnosis, including the pathologic correlation. Familiarity with these entities may improve diagnostic accuracy and patient management. PMID:25010368

  1. Tubulointerstitial Nephropathies in HIV-Infected Patients over the Past 15 Years: A Clinico-Pathological Study

    PubMed Central

    Zaidan, Mohamad; Lescure, François-Xavier; Brochériou, Isabelle; Dettwiler, Sarah; Guiard-Schmid, Jean-Baptiste; Pacanowski, Jérôme; Rondeau, Eric; Pialoux, Gilles; Girard, Pierre-Marie; Ronco, Pierre

    2013-01-01

    Summary Background and objectives The therapy and outcome of HIV infection have dramatically changed over the last 15 years, resulting in a change in renal complications. This study analyzed the characteristics of HIV-infected patients and biopsy-proven tubulointerstitial nephropathies to define disease patterns and therapeutic implications. Design, setting, participants, & measurements A clinico-pathologic retrospective study of 59 consecutive renal biopsies showing predominant tubular and/or interstitial lesions in HIV-infected patients referred to the nephrology department between 1995 and 2011 was performed. HIV-associated nephropathy and vascular diseases were excluded from the study. Results Tubulointerstitial nephropathies accounted for 26.6% of 222 native renal biopsies performed in HIV-infected patients. Two pathologic groups were analyzed, tubulopathy and interstitial nephritis, which represented 49% and 51% of tubulointerstitial nephropathies, respectively. Most patients presented with AKI (76.3%) and high-grade proteinuria (57.7%). Drug-related nephrotoxicity was the leading cause (52.5%). Alternative etiologies included infections (15.2%), dysimmune disorders (8.5%), malignancies (3.4%), and chronic (10.2%) and acute (10.2%) tubulointerstitial nephropathies of undetermined origin. Tubulopathy was strongly associated with antiretroviral drug toxicity (75.9%) and mostly caused by tenofovir (55.2%), which was associated with proximal tubular dysfunction (87.5%), overt Fanconi’s syndrome (37.5%), and nephrogenic diabetes insipidus (12.5%). Interstitial nephritis was associated with a broader spectrum of pathologic lesions and etiologies. Conclusions In this series, tubulointerstitial nephropathies accounted for 26.6% of renal diseases in HIV-infected patients. Considering the therapeutic implications of diagnoses of drug toxicity, infection, and dysimmune syndromes, this study underscores the importance of monitoring renal parameters in HIV-infected patients and points to the relevance of kidney biopsy to allow an accurate diagnosis. PMID:23430209

  2. Clinico-immunologic evaluation of allergy to Himalayan tree pollen in atopic subjects in India--a new record.

    PubMed

    Bist, Arnima; Kumar, Lata; Roy, Indrani; Ravindran, P; Gaurs, S N; Singh, A B

    2005-01-01

    Exposure to local pollen allergens has a direct bearing on the prevalence of allergic symptoms among the inhabiting atopic population. The populations in the Himalayas and around it are exposed to a variety of pollen grains from trees growing in the region, but the pollen-population interaction has not been clinically investigated. Himalayan tree pollen from five different taxa, i.e. Alnus nitida (AN), Betula utilis (BU), Cedrus deodara (CD), Mallotus phillipensis (MP) and Quercus incana (QI) were evaluated for their allergenicity in the Indian population by in vivo (skin prick test) and in vitro (ELISA) clinico-immunological methods. The presence of specific IgE against these tree pollen in the sera of skin test positive patients was taken as evidence for sensitization to these pollen. The average skin positivity in atopic populations recorded at different allergy centers in India varied from 2.2% against AN, to 4.7% against MP pollen. Significantly raised specific IgE against these pollen were observed in the sera of hypersensitive patients. The sensitization pattern to Himalayan tree pollen in these atopic populations varied. It was concluded that skin prick test positivity and raised IgE antibodies specific to AN, BU, CD, MP and QI established Himalayan tree pollen as important sensitizers in the atopic populations of India. A high incidence of skin sensitivity was observed to pollen antigens of Cedrus deodara, Mallotus phillipensis and Quercus incana in patients of Chandigarh residing in the hills and foothills of the Himalayas while Alnus nitida, Betula utilis and Cedrus deodara were important sensitizers in Delhi patients. The skin sensitization pattern against these pollen was in accordance with the level of exposure to these pollen of the subjects residing in that part of the country. PMID:16252835

  3. Anemia refrattaria con eccesso di blasti (AREB) in paziente con artrite reumatoide in trattamento con methotrexate ed infliximab: descrizione di un caso clinico Case report: AREB in a patient with rheumatoid arthritis treated with methotrexate and infliximab

    Microsoft Academic Search

    Giuseppe D'Alessandro; Maria Rosaria Bianco; Spiridion Politis; Celestino Ferrandina; Giuseppe Rossi; Emanuele Altomare

    SUMMARY Anti TNF-? drugs seem to be the new frontier of Rheumatoid Arthritis (RA) therapy. The association infliximab methotrexate has been approved for the treatment of RA not responding to the classic therapy, but the short clinical experience in using antiTNF-? molecules brings to segnalation of new risks or adverse events. We describe a case of a patient, treated for

  4. Evolution of Charcot-Marie-Tooth disease type 1A duplication: a 2-year clinico-electrophysiological and lower-limb muscle MRI longitudinal study.

    PubMed

    Pelayo-Negro, Ana L; Gallardo, Elena; García, Antonio; Sánchez-Juan, Pascual; Infante, Jon; Berciano, José

    2014-04-01

    The objective of this study was to analyze Charcot-Marie-Tooth disease type 1A (CMT1A) evolution. We conducted a 2-year longitudinal study in 14 CMT1A patients and 14 age- and sex-matched controls. In the patients, we performed neurological examination with hand-held dynamometry, electrophysiology, and lower-limb muscle MRI, both at baseline and 2 years later, while controls were examined at baseline only. Patients' ages ranged from 12 to 51 years. Outstanding manifestations on initial evaluation included pes cavus, areflexia, lower-limb weakness, and foot hypopallesthesia. In evaluating muscle power, good correlation was observed between manual testing and dynamometry. Compared to controls, Lunge, 10-Meter-Walking, and 9-Hole-Peg tests were impaired. Their CMT neuropathy score and functional disability scale showed that patients exhibited mild phenotype and at most slight walking difficulty. Electrophysiology revealed marked nerve conduction slowing and variable compound muscle action potential amplitude reduction. On lower-limb muscle MRI, there was distally accentuated fatty infiltration accompanied by edema in calf muscles. All these clinico-electrophysiological and imaging findings remained almost unaltered during monitoring. Using multivariate analysis, no significant predictors of progression associated to the disease were obtained. We conclude that in the 2-year period of study, CMT1A patients showed mild progression with good concordance between clinico-electrophysiological and imaging findings. PMID:24449066

  5. Chronic lymphocytic leukemia in the elderly: clinico-biological features, outcomes, and proposal of a prognostic model

    PubMed Central

    Baumann, Tycho; Delgado, Julio; Santacruz, Rodrigo; Martínez-Trillos, Alejandra; Royo, Cristina; Navarro, Alba; Pinyol, Magda; Rozman, María; Pereira, Arturo; Villamor, Neus; Aymerich, Marta; López, Cristina; Carrió, Anna; Montserrat, Emili

    2014-01-01

    We investigated the clinico-biological features, outcomes, and prognosis of 949 patients with chronic lymphocytic leukemia according to age. No biological differences (cytogenetics by fluorescent in situ hybridization, IGHV, ZAP-70, CD38, NOTCH1, SF3B1) were found across age groups. Elderly patients (>70 years; n=367) presented more frequently with advanced disease (Binet C/Rai III-IV: 10/12% versus 5/5%; P<0.001), were treated less frequently (23.8% versus 41.9% at 3 years; P<0.001) and in most cases did not receive highly effective regimens and thus had a lower overall response rate (49% with 14% having complete responses versus 69% with 31% having complete responses; P<0.001). The elderly patients also had a shorter overall survival (6.6 versus 13.3 years; P<0.001) and higher disease-unrelated mortality (34.9% versus 6.9% at 10 years; P<0.001). However, disease-attributable mortality was not significantly different between younger and older patients. A combination of Binet stage, ZAP-70 level, ?2-microglobulin concentration and comorbidity identified two risk groups (low-risk: 0–1 parameters; high-risk: 2–4 parameters) with different overall survivals (median: 6.8 versus 11.4 years, P<0.001). In patients requiring treatment, comorbidity at treatment (Cumulative Illness Rating Scale-T>4; hazard ratio 2.2, P<0.001) and response (treatment failure versus response: hazard ratio 1.60, P<0.04) were the most important prognostic factors for overall survival. In conclusion, in our series, elderly patients with chronic lymphocytic leukemia did not present with any biological features distinct from those of younger patients, but did have a poorer clinical outcome. This study highlights the importance of comprehensive medical care, achieving response to therapy, and specific management strategies for elderly patients with chronic lymphocytic leukemia. PMID:24972773

  6. Japanese encephalitis associated acute encephalitis syndrome cases in West Bengal, India: A sero-molecular evaluation in relation to clinico-pathological spectrum.

    PubMed

    Sarkar, Arindam; Datta, Somenath; Pathak, Bani K; Mukhopadhyay, Subhra K; Chatterjee, Shyamalendu

    2015-08-01

    Japanese encephalitis (JE) is a major public health problem in Asia and worldwide and it is responsible mainly for viral acute encephalitis syndrome (AES). The sole etiologic agent of JE is Japanese encephalitis virus (JEV). Although JE/AES cases have been regarded traditionally as a disease of children, a growing number of patients with JE/AES cases are also seen in the adult age group every year in the state of West Bengal, India in spite of vaccination. Therefore, a systematic study was performed to differentiate and characterize the clinico-pathological parameters and viral diversity among the patients of different age groups. Viral diversity was also evaluated from the JE/AES cases, depending on their disease severity. A total of 441 JE/AES cases were included in this study. By MAC-ELISA, 111 samples were found JEV IgM positive and among the IgM negative cases, 26 samples were found RT-PCR positive against JEV infection. Neck rigidity, abnormal behavior, convulsion, protein in CSF, WBC in CSF, and aspartate transaminase in blood differed significantly among the patients of pediatric-adolescent and adult group in both IgM positive and RT-PCR positive cases. Viral diversity was increased significantly in the pediatric-adolescent group compared to adult patients. Interestingly, with the rise in disease severity the viral diversity was found to be increased among the patients, irrespective of their age distribution. Based on clinico-pathological parameters and analysis of viral diversity, it can be concluded that viral diversity which occurs naturally is likely to affect disease severity, especially in the patients of pediatric-adolescent group. J. Med. Virol. 87:1258-1267, 2015. © 2015 Wiley Periodicals, Inc. PMID:25939919

  7. [Correlation of clinico-neurological peculiarities and morphological signs of small hernias (protrusion) of the lumbar intervertebral discs in formation of discogenic pain syndromes in patients of different age].

    PubMed

    Khizhniak, M V; Makeeva, T I; Pri?mak, I V

    2014-01-01

    Morphological signs of small hernias (protrusion) of intervertebral discs (IVD), the results of a neurovisualizing methods of investigation and clinico-neurological features of osteochondrosis as well, were summarized. In young and middle age patients morphological chatacteristics of small hernias (protrusion) of IVD, data of neurovisualizing methods of investigation have had correlated with clinico-neurological features of the disease and were the key determinants while performance of the puncture laser microdiscectomy. In a middle age and elderly patients a weak correlation was noted between the IVD protrusion dimensions and intensity of a lumbar and radicular pain syndromes, functional activity (Osvestry index), what have had permitted to apply a pathogenetically substantiated method of a durable epidural pharmacotherapy. The investigation results witness the necessity of differentiated application of the puncture methods of treatment for the pain discogenic syndromes in patients of different age. PMID:24923150

  8. Nuclear beta-catenin accumulation as reliable marker for the differentiation between cystic craniopharyngiomas and rathke cleft cysts: a clinico-pathologic approach.

    PubMed

    Hofmann, Bernd M; Kreutzer, Jürgen; Saeger, Wolfgang; Buchfelder, Michael; Blümcke, Ingmar; Fahlbusch, Rudolf; Buslei, Rolf

    2006-12-01

    Clinical and histopathologic differentiation of cystic lesions from the sellar region, that is, craniopharyngiomas (CPs) and Rathke cleft cysts (RCCs), is challenging and has paramount importance with respect to variable clinical manifestation and adapted surgical treatment strategies in both entities. Here, we retrospectively evaluated clinico-pathologic findings in 81 patients presenting with a cystic tumor located in the sellar region. All patients underwent transsphenoidal or transcranial resections. Microscopic inspection of surgical specimens identified CP in 51 patients, and RCC in 30 patients. Amongst the panel of immunohistochemical marker proteins used for histopathologic analysis, nuclear accumulation of beta-catenin was detectable only in CP. On the basis of the histopathologic and immunohistochemical analysis, clinical presentation (sex, age, ophthalmologic, and endocrinologic deficits), imaging (tumor location, size, and calcification), as well as a description of cyst contents obtained during operation were retrospectively evaluated. In purely cystic CPs, an isointense signal was more frequent in T1-weighted magnetic resonance images and calcification of the tumor capsule in computed tomography scans. In addition, the size of RCC was smaller and this tumor entity was more often located within the sella. Aberrant (nuclear) immunohistochemical staining for beta-catenin appeared, however, as most reliable factor for the differentiation between purely cystic CPs and RCCs, whereas tumor location, tumor size, and calcification of the tumor capsule were less consistent parameters. The data are compatible with distinct pathogenic pathways associated with these related histopathologic entities. PMID:17122517

  9. Clinico-biological features of 5202 patients with acute lymphoblastic leukemia enrolled in the Italian AIEOP and GIMEMA protocols and stratified in age cohorts

    PubMed Central

    Chiaretti, Sabina; Vitale, Antonella; Cazzaniga, Gianni; Orlando, Sonia Maria; Silvestri, Daniela; Fazi, Paola; Valsecchi, Maria Grazia; Elia, Loredana; Testi, Anna Maria; Mancini, Francesca; Conter, Valentino; te Kronnie, Geertruy; Ferrara, Felicetto; Di Raimondo, Francesco; Tedeschi, Alessandra; Fioritoni, Giuseppe; Fabbiano, Francesco; Meloni, Giovanna; Specchia, Giorgina; Pizzolo, Giovanni; Mandelli, Franco; Guarini, Anna; Basso, Giuseppe; Biondi, Andrea; Foà, Robin

    2013-01-01

    The outcome of children and adults with acute lymphoblastic leukemia is markedly different. Since there is limited information on the distribution of clinico-biological variables in different age cohorts, we analyzed 5202 patients with acute lymphoblastic leukemia enrolled in the Italian multicenter AIEOP and GIMEMA protocols and stratified them in nine age cohorts. The highest prevalence of acute lymphoblastic leukemia was observed in children, although a second peak was recorded from the 4th decade onwards. Interestingly, the lowest incidence was found in females between 14–40 years. Immunophenotypic characterization showed a B-lineage in 85.8% of patients: a pro-B stage, associated with MLL/AF4 positivity, was more frequent in patients between 10–50 years. T-lineage leukemia (14.2%) was rare among small children and increased in patients aged 10–40 years. The prevalence of the BCR/ABL1 rearrangement increased progressively with age starting from the cohort of patients 10–14 years old and was present in 52.7% of cases in the 6th decade. Similarly, the MLL/AF4 rearrangement constantly increased up to the 5th decade, while the ETV6/RUNX1 rearrangement disappeared from the age of 30 onwards. This study shows that acute lymphoblastic leukemia in adolescents and young adults is characterized by a male prevalence, higher percentage of T-lineage cases, an increase of poor prognostic molecular markers with aging compared to cases in children, and conclusively quantified the progressive increase of BCR/ABL+ cases with age, which are potentially manageable by targeted therapies. PMID:23716539

  10. Entrevista con Vicente Leñero

    E-print Network

    Day, Stuart A.

    2004-01-01

    también en la vida profesional de Leñero. Poco después de este acontecimiento algunos de los ex-colaboradorcs de Excélsior, dirigidos nuevamen te por Julio Scherer y con Leñero como vocal, forman una agencia de noticias que empieza con dos máquinas... de la primera edición de Proceso, Leñero decide ignorar este incidente para hacerlo materia de su novela testimonial Los periodistas, al mismo tiempo que lo instituye en travesura para no sucumbir ante el miedo. Su formación periodística, combinada...

  11. Evaluation of Serum Levels of HER2, MMP-9, Nitric Oxide, and Total Antioxidant Capacity in Egyptian Breast Cancer Patients: Correlation with Clinico-Pathological Parameters.

    PubMed

    Rashad, Yara A; Elkhodary, Tawfik R; El-Gayar, Amal M; Eissa, Laila A

    2014-03-01

    Breast cancer is by far the most common cancer in women worldwide and the main cause of cancer-related mortality. Breast cancer accounts for 38% of all malignancies among Egyptian women. The aim of our study was to evaluate the serum levels of human epidermal growth factor receptor-2 (HER2), matrix metalloproteinase-9 (MMP-9), nitric oxide (NO), and total antioxidant capacity (TAC) in breast cancer patients and to correlate these markers with clinico-pathological parameters. Serum HER2, MMP-9, and carcinoma antigen 15-3 (CA 15-3) were assessed in 80 breast cancer patients and ten healthy subjects as a control group by the enzyme-linked immunosorbent assay (ELISA) technique while NO and TAC were assessed by a colorimetric method. Serum HER2 was ?15 ng/mL in nine patients (11.3%). High HER2 ECD levels were significantly associated with tissue HER2 (P<0.0001), metastasis (P= 0.0024), and negativity of both estrogen (P=0.0075) and progesterone (P=0.0239) receptors. Serum MMP-9 (P=0.0013), NO (P<0.0001), and CA 15-3 (P<0.0001) were significantly increased while serum TAC was significantly (P=0.01) decreased in breast cancer patients as compared to the control group. Serum MMP-9 was increased significantly (P=0.028) in metastatic patients as compared to non-metastatic patients. We found a positive correlation between serum HER2 and CA 15-3 (r=36, p=0.005). In conclusion, serum HER2 reflects the tissue HER2 status of breast cancer, so the determination of serum HER2 is helpful in assessing HER2 status, but in addition, a high level may reflect metastatic disease. Also, serum MMP-9 can be useful for denoting the development of metastasis in breast cancer patients. Follow-up is needed to evaluate the value of serum HER2 and MMP-9 as prognostic markers. PMID:24634847

  12. Recent outbreak of cutaneous anthrax in Bangladesh: clinico-demographic profile and treatment outcome of cases attended at Rajshahi Medical College Hospital

    PubMed Central

    2012-01-01

    Background Human cutaneous anthrax results from skin exposure to B. anthracis, primarily due to occupational exposure. Bangladesh has experienced a number of outbreaks of cutaneous anthrax in recent years. The last episode occurred from April to August, 2011 and created mass havoc due to its dreadful clinical outcome and socio-cultural consequences. We report here the clinico-demographic profile and treatment outcome of 15 cutaneous anthrax cases attended at the Dermatology Outpatient Department of Rajshahi Medical College Hospital, Bangladesh between April and August, 2011 with an aim to create awareness for early case detection and management. Findings Anthrax was suspected primarily based on cutaneous manifestations of typical non-tender ulcer with black eschar, with or without oedema, and a history of butchering, or dressing/washing of cattle/goat or their meat. Diagnosis was established by demonstration of large gram-positive rods, typically resembling B. anthracis under light microscope where possible and also by ascertaining therapeutic success. The mean age of cases was 21.4?years (ranging from 3 to 46?years), 7 (46.7%) being males and 8 (53.3%) females. The majority of cases were from lower middle socioeconomic status. Types of exposures included butchering (20%), contact with raw meat (46.7%), and live animals (33.3%). Malignant pustule was present in upper extremity, both extremities, face, and trunk at frequencies of 11 (73.3%), 2 (13.3%), 1 (6.7%) and 1 (6.7%) respectively. Eight (53.3%) patients presented with fever, 7 (46.7%) had localized oedema and 5 (33.3%) had regional lymphadenopathy. Anthrax was confirmed in 13 (86.7%) cases by demonstration of gram-positive rods. All cases were cured with 2?months oral ciprofloxacin combined with flucoxacillin for 2?weeks. Conclusions We present the findings from this series of cases to reinforce the criteria for clinical diagnosis and to urge prompt therapeutic measures to treat cutaneous anthrax successfully to eliminate the unnecessary panic of anthrax. PMID:22929128

  13. Entrevista con Sergio Vodanovic

    E-print Network

    Agosin, Marjorie

    1984-04-01

    de pionero dentro del teatro chileno contemporáneo. Este es el tema de la entrevista cuyas preguntas fueron contestadas directamente por Vodanovic y transcritas en la misma manera como aparecen en el texto. ¿Cómo ves tú el teatro chileno desde el... remora de los teatros que antes eran líderes, de los teatros universitarios que, en general, se mantienen dentro de una posición de dar obras clásicas u obras de teatros universal, y con mucho temor respecto al teatro chileno. ¿ Tú crees que el público...

  14. Entrevista con Santiago García

    E-print Network

    Baycroft, Bernard

    1982-04-01

    muchas resistencias que había entre la gente de tea tro a este fenómeno de la creación colectiva, que aparece compitiendo con el autor y entrando al terreno de la creatividad artística. ¿Cómo es esto diferente a la práctica del Teatro Experimental de... teatral que nosotros estamos produciendo porque el tener este pú blico y un campo de experimentación tan fecundo como es ése de los sectores populares, más avanzados, más revolucionarios, más progresistas de nuestro país, garantizaría ya la...

  15. Entrevista con Enrique Buenaventura

    E-print Network

    Dí ez, Luys A.

    1981-04-01

    el individuo; entrañable y sencillo, conversador penetrante y muy ameno. Y fue en esta capacidad, aprovechando una falla en la programación, que una tarde le acompañamos a ver A Chorus Line, el musical de Bennett, que le iba a interesar... todavía muestran las huellas de los terribles bombardeos e incendios, con las paredes acribilladas por todas partes. Y luego las historias que iba contando todo el mundo, tantas que en realidad sería muy difícil escoger. Yo he seleccionado unas pocas y...

  16. Crnica ornitolgica con las citas

    E-print Network

    Carrete, Martina

    Crónica ornitológica con las citas más relevantes del año 2000 Estudio de la avifauna de las balsas seguimiento que ha realizado a la avifauna del paraje. · La crónica ornitológica del año 2000, con las

  17. Entrevista con Wilberto Cantón

    E-print Network

    Vé lez, Joseph F.

    1979-10-01

    FALL 1979 71 Entrevista con Wilberto Cantón JOSEPH F. VÉLEZ Señor Cantón, ¿quisiera usted decirme donde y cuándo nació?1 Nací en la ciudad de Mérida, Yucatán, el día 15 de julio de 1925. ¿Puede usted ahora decirnos un poco de su educación... primaria, secundaria y universitaria, ya haya sido en México o en el extranjero? Sí. Yo hice mis primeros estudios allá en la ciudad de Mérida y, posterior mente, vine a México, y aquí cursé el bachillerato y mi profesión, que es de abogado. Terminé...

  18. Nam Con Son Basin

    SciTech Connect

    Tin, N.T.; Ty, N.D.; Hung, L.T.

    1994-07-01

    The Nam Con Son basin is the largest oil and gas bearing basin in Vietnam, and has a number of producing fields. The history of studies in the basin can be divided into four periods: Pre-1975, 1976-1980, 1981-1989, and 1990-present. A number of oil companies have carried out geological and geophysical studies and conducted drilling activities in the basin. These include ONGC, Enterprise Oil, BP, Shell, Petro-Canada, IPL, Lasmo, etc. Pre-Tertiary formations comprise quartz diorites, granodiorites, and metamorphic rocks of Mesozoic age. Cenozoic rocks include those of the Cau Formation (Oligocene and older), Dua Formation (lower Miocene), Thong-Mang Cau Formation (middle Miocene), Nam Con Son Formation (upper Miocene) and Bien Dong Formation (Pliocene-Quaternary). The basement is composed of pre-Cenozoic formations. Three fault systems are evident in the basin: north-south fault system, northeast-southwest fault system, and east-west fault system. Four tectonic zones can also be distinguished: western differentiated zone, northern differentiated zone, Dua-Natuna high zone, and eastern trough zone.

  19. Relaciones trigonometricas Operaciones con logaritmos

    E-print Network

    Relaciones trigonom´etricas Operaciones con logaritmos Funciones elementales y sus gr´aficas Gr´aficas de funciones elementales L´imites Continuidad Tema 1: Repaso de conocimientos previos. Funciones´etricas Operaciones con logaritmos Funciones elementales y sus gr´aficas Gr´aficas de funciones elementales L

  20. LA PRÁCTICA EDUCATIVA CON DISCAPACITADOS

    Microsoft Academic Search

    Eduardo Ullate Rada

    2010-01-01

    La práctica educativa con discapacitados suponía un reto para mí. Con la realización del curso de monitor de tiempo libre me vi obligado a realizar unas prácticas educativas que no sabía en qué lugar y ciudad iba a realizarlas. Tras una larga meditación decidí explorar un “nuevo mundo”, el de la educación de personas discapacitadas.

  1. Planificación Neuroquirúrgica con Software Osirix

    PubMed Central

    Jaimovich, Sebastián Gastón; Guevara, Martin; Pampin, Sergio; Jaimovich, Roberto; Gardella, Javier Luis

    2014-01-01

    Introducción: La individualidad anatómica es clave para reducir el trauma quirúrgico y obtener un mejor resultado. Actualmente, el avance en las neuroimágenes ha permitido objetivar esa individualidad anatómica, permitiendo planificar la intervención quirúrgica. Con este objetivo, presentamos nuestra experiencia con el software Osirix. Descripción de la técnica: Se presentan 3 casos ejemplificadores de 40 realizados. Caso 1: Paciente con meningioma de la convexidad parasagital izquierda en área premotora; Caso 2: Paciente con macroadenoma hipofisario, operada previamente por vía transeptoesfenoidal en otra institución con una resección parcial; Caso 3: Paciente con lesiones en pedúnculo cerebeloso medio bilateral. Se realizó la planificación prequirúrgica con el software OsiriX, fusionando y reconstruyendo en 3D las imágenes de TC e IRM, para analizar relaciones anatómicas, medir distancias, coordenadas y trayectorias, entre otras funciones. Discusión: El software OsiriX de acceso libre y gratuito permite al cirujano, mediante la fusión y reconstrucción en 3D de imágenes, analizar la anatomía individual del paciente y planificar de forma rápida, simple, segura y económica cirugías de alta complejidad. En el Caso 1 se pudo analizar las relaciones del tumor con las estructuras adyacentes para minimizar el abordaje. En el Caso 2 permitió comprender la anatomía post-operatoria previa del paciente, para determinar la trayectoria del abordaje transnasal endoscópico y la necesidad de ampliar su exposición, logrando la resección tumoral completa. En el Caso 3 permitió obtener las coordenadas estereotáxicas y trayectoria de una lesión sin representación tomográfica. Conclusión: En casos de no contar con costosos sistemas de neuronavegación o estereotáxia el software OsiriX es una alternativa a la hora de planificar la cirugía, con el objetivo de disminuir el trauma y la morbilidad operatoria. PMID:25165617

  2. Una entrevista con Emilio Carballido.

    E-print Network

    Vé lez, Joseph F.

    1973-10-01

    FALL 1973 17 Una entrevista con Emilio Carballido JOSEPH F. VÉLEZ V. Señor Carballido, ¿podría decirme cuándo comenzó a interesarse en escribir? C. Fui un niño precoz que escribió mucho desde muy chamaquito. V. ¿Qué escribió primero: poesía... han presentado aquí? C. Todavía no. Pero parece que el teatro de Fuentes no es realista, y está más bien emparentado con otras corrientes. El teatro de Leñero tiende a ser teatro documental. El tuerto es rey, de Fuentes, tiene, parece...

  3. Programando con Igualdad Similar Estricta

    Microsoft Academic Search

    Ginés Moreno; Vicente Pascual

    Resumen En los últimos años, hemos sido testigos del importante papel que la lógica difusa o borrosa (fuzzy logic) ha jugado en el desarrollo de sofisticadas aplicaciones software en campos tan diversos como los sistemas expertos, inteligencia artificial, control industrial, medicina, etc. Con el objetivo de facilitar el desarrollo de tales aplicaciones, mucho más recientemente ha surgido el interés por

  4. Cefalea con criterios de alarma

    Microsoft Academic Search

    Nuria Martínez Sánchez; Antonio Palasí Franco; Luis Miguel Martínez Sánchez

    2010-01-01

    La alta prevalencia de cefalea en la población general hace que sea uno de los principales motivos de consulta neurológica en Atención Primaria tanto para el médico de familia como para el neurólogo. Pese a que la mayoría de las consultas están motivadas por cefaleas primarias (migraña y cefalea tensional son, con mucho, las cefaleas más prevalentes) hay que tener

  5. todasuvida: Las personas con diabetes son ms

    E-print Network

    diabetes Controlesu todasuvida: Las personas con diabetes son más propensas a padecer de enfermedades del corazón que quienes no tienen diabetes. Boletín 631 D Las personas con diabetes tienen mayor- res relacionados con la diabetes, como derrame cerebral, mala circulación en las piernas y pies e

  6. Sulla termodinamica dei materiali con memoria

    Microsoft Academic Search

    Dario Graffi

    1974-01-01

    Sunto  Si espone limitandosi, per semplicità, ai corpi solidi con deformazioni infinitesime, la teoria di Coleman sulla termodinamica\\u000a dei materiali con memoria. Si considerano poi, in particolare, i corpi viscoelastici lineari e identificata l'energia libera\\u000a con l'energia potenziale interna di Volterra, si deducono, dalla termodinamica, proprietà dei coefficenti di memoria, finora\\u000a ammesse come intuitive e si ottiene una rapida dimostrazione del

  7. A clinico-epidemiological study of donovanosis.

    PubMed

    Garg, B R; Baruah, M C; Oudeacoumar, P; Kumar, V

    1989-01-01

    Researchers conducted a retrospective study of confirmed cases of donovanosis, a sexually transmitted disease (STD), between January 1980- December 1987 at the STD clinic at the Jawaharlal Institute of Postgraduate Medical Education and Research in Pondicherry, India to determine if a change in the disease's trend occurred. 6.6% of all STD cases at the clinic had donovanosis, especially among 20-30 year olds. This compared to 5.4% in 1968-1969. Incidence did fall, however, to 3.6% in 1987. Incidence among males gradually increased from 1980-1982 then gradually fell. This decline was proportional to the total number of STD patients. All but 1 female reported not having sex outside of marriage. A low of 25% of both husbands and wives of married pairs had donovanosis. The most frequent clinical type of donovanosis was fleshy exuberant then either necrotic or sclerotic types. It affected mainly the genitalia, Syphilis was the most likely associated STD in both sexes. Even though there was a gradual decline in donovanosis, it still made up a major share of all STDs despite the availability of effective treatment (co-trimoxazole, chloromycetin, doxycycline, and tetracycline). In this same time period, a 7.2% and 1.7% increase in other STDs among female and male teenagers respectively occurred, yet, except for 1 case, there were no cases of donovanosis among teenagers. A possible explanation for the inability of this clinic to control donovanosis could be poor contact tracing. PMID:12284234

  8. [Endomyocardial fibrosis (its clinico-echocardiographic characteristics)].

    PubMed

    Bapumiia, M; Solomakhina, N I; Sumarokov, A V

    1996-01-01

    To compare clinical and echocardiographic features in patients with restrictive cardiomyopathy (RCMP), 15 patients (9 males and 6 females, mean age 34.93 +/- 1.03 years, duration of the disease 9 +/- 4.2 months) were examined using complete echocardiographic and doppler echocardiographic investigation in impulse regimen. Endomyocardial fibrosis was not obvious clinically, but should be suspected in dyspnea upon a weak exercise, undue fatiguability, tachycardia in normal arterial pressure and size of the heart. Echocardiographic indications, on the contrary, were rather specific. Endomyocardial fibrosis is characterized by diminished ventricular cavities, thickening of the endocardium and subvalvular structures, changed shape of ventricular cavity, echo-CG signs of passive pulmonary hypertension, diastolic dysfunction of the left and right ventricles. PMID:9005618

  9. Clinico-Histologic Conferences: Histology and Disease

    ERIC Educational Resources Information Center

    Shaw, Phyllis A.; Friedman, Erica S.

    2012-01-01

    Providing a context for learning information and requiring learners to teach specific content has been demonstrated to enhance knowledge retention. To enhance students' appreciation of the role of science and specifically histology in clinical reasoning, disease diagnosis, and treatment, a new teaching format was created to provide clinical…

  10. [Clinico-epizootologic studies in Gumboro disease].

    PubMed

    Liutskanov, D; Nikolov, N V; Lipov, I; Stamenov, M

    1978-01-01

    The disease was established on a poultry dressing combine, affecting birds at the age of three to eleven weeks. It ran its course with clinical symptoms and epizootiology that were characteristic of it. A total of 8778 birds or 10% succumbed to the disease. Its notification on a newly built poultry dressing combine made it reasonable to believe that possibility existed of its transmission through the hatcheries. The outbreak occurred almost simultaneously with the inadequate feeding that was admitted on the combine. The cyclogramme concerning the admission of birds and its strict application were shown to influence the course of the epizootic process. Clinical and epizootiological investigations coupled with virological and histopathological studies rendered it possible to draw the conclusion that the birds on the combine were affected with infectious bursitis, identified as Gumboro disease. It was established for the first time in this country. PMID:214935

  11. [Mesenchymal chondrosarcoma (clinico-morphological study)].

    PubMed

    Solov'ev, Iu N; Eremina, L A; Petrovichev, N N; Khmelev, O N; Kasumov, I V

    1983-01-01

    Mesenchymal chondrosarcoma was found in 11 out of 161 patients with chondrosarcoma of the bone. The assaultive nature of the disease is illustrated by the following data: the period between the manifestation of symptoms and the first visit to the doctor was 5.9 +/- 4.3 months; metastases were detected within 20.56 +/- 6.04 months and 8 patients out of 10 died within the first 5 years. Two histological structures were observed: those of the chondrosarcoma type and hemangiopericytoma-like structures formed of small atypical cells. PMID:6636625

  12. Modeling Dynamic Domains with ConGolog

    Microsoft Academic Search

    Yves Lespérance; Todd G. Kelley; John Mylopoulos; Eric S. K. Yu

    1999-01-01

    In this paper, we describe the process specification language ConGolog and show how it can be used to model business processes for requirements analysis. In ConGolog, the effects of actions in a dynamic domain are spec- ified in a logical framework. This supports modeling even in the absence of complete information. The behavior of agents in the domain is specified

  13. ProteoCon kit Handbook www.geba.org ProteoCon Kit

    E-print Network

    Lebendiker, Mario

    The ProteoCon kit technology ................................................................3 Mini bottle 2 bottles Buffer WBD2 (washing buffer) 30 ml 60 ml ProteoConN kit 10 units 20 units Proteo. Limitations on Product use The ProteoCon kits were developed designed and are being sold for resear

  14. Tensión postraumática relacionada con el cáncer (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca de la tensión postraumática y síntomas relacionados en los pacientes con cáncer, sobrevivientes del cáncer y miembros de la familia. Se discuten la evaluación y tratamiento de estos síntomas.

  15. LA MAESTRA EN CIENCIAS (NEUROBIOLOGA), Con el objetivo de formar profesionales con conocimientos slidos de los

    E-print Network

    Islas, León

    LA MAESTRÍA EN CIENCIAS (NEUROBIOLOGÍA), Con el objetivo de formar profesionales con conocimientos, neurociencias, psicobiología, física, matemáticas, estadística y metodología de la ciencia, a presentar su Nacional de Posgrado de Calidad del Consejo Nacional de Ciencia y Tecnología en categoría: COMPETENTE

  16. Too Many Minas Spoil The Con

    E-print Network

    2007-02-13

    and in livejournal, I suddenly got the urge to go to a con again. The thought of a proper anime con, with people dressing up and showing videos and panels and discussions about the series and even about writing fanfiction, well, I thought that you must be involved...'t write proper porn. There's more to it than just the penis. I mean, erotica. Not porn. Um, sorry. That was just the first day. Day two had the writing panels and the surprise guest standing in for H.P Lovecraft (I mean, everyone knew that it was a...

  17. CON Advising Academic Year 2013-2014

    E-print Network

    Carter, John

    in achieving the learning outcomes, ensuring student academic success, and planning to achieve the studentsCON Advising Academic Year 2013-2014 Advisors: Rita Tower Kelly Fanning Office: Garrand 403 Garrand students to make decisions about their academic, personal and professional pathways, and to encourage

  18. Diagramas de Voronoi con funciones temporales \\Lambda

    E-print Network

    Palop del Río, Belén

    Diagramas de Voronoi con funciones temporales \\Lambda Ferran Hurtado, Bel'en Palop, Vera Sacrist'etricas. En este trabajo se describen los diagramas de Voronoi dados por funciones temporales surgidas al introducir en el plano una red de transporte. Dichas funciones pueden dar lugar a bisectores que no forman un

  19. Google Scholar: the pros and the cons

    Microsoft Academic Search

    Péter Jacsó

    2005-01-01

    Purpose – To identify the pros and the cons of Google Scholar. Design\\/methodology\\/approach – Chronicles the recent history of the Google Scholar search engine from its inception in November 2004 and critiques it with regard to its merits and demerits. Findings – Feels that there are massive content omissions presently but that, with future changes in its structure, Google Scholar

  20. Teorías sobre cobertura con contratos de futuro

    Microsoft Academic Search

    Vicent Aragó Manzana

    2009-01-01

    En este trabajo se presenta una revisión de las principales teorías sobre cobertura con contratos de futuro y de los distintos métodos de estimación utilizados para determinar el ratio de cobertura óptimo. La aproximación a la cobertura más utilizada en la literatura especializada es la basada en el modelo de la teoría de carteras. No obstante, debido a sus hipótesis

  1. VANET Routing Protocols: Pros and Cons

    E-print Network

    Paul, Bijan; Bikas, Md Abu Naser

    2012-01-01

    VANET (Vehicular Ad-hoc Network) is a new technology which has taken enormous attention in the recent years. Due to rapid topology changing and frequent disconnection makes it difficult to design an efficient routing protocol for routing data among vehicles, called V2V or vehicle to vehicle communication and vehicle to road side infrastructure, called V2I. The existing routing protocols for VANET are not efficient to meet every traffic scenarios. Thus design of an efficient routing protocol has taken significant attention. So, it is very necessary to identify the pros and cons of routing protocols which can be used for further improvement or development of any new routing protocol. This paper presents the pros and cons of VANET routing protocols for inter vehicle communication.

  2. Somatic cell nuclear transfer: pros and cons.

    PubMed

    Sumer, Huseyin; Liu, Jun; Tat, Pollyanna; Heffernan, Corey; Jones, Karen L; Verma, Paul J

    2009-01-01

    Even though the technique of mammalian SCNT is just over a decade old it has already resulted in numerous significant advances. Despite the recent advances in the reprogramming field, SCNT remains the bench-mark for the generation of both genetically unmodified autologous pluripotent stem cells for transplantation and for the production of cloned animals. In this review we will discuss the pros and cons of SCNT, drawing comparisons with other reprogramming methods. PMID:20232594

  3. Too Many Minas Spoil The Con 

    E-print Network

    2007-02-13

    1 12:08 pm February 13th, 2007 vuirneen A semi-private email to Mina de Malfois Is anyone familiar with the writings of mina_de_malfois? I wrote this email to her, based entirely on her Minaverse, between... midnight and two am last night and I just wanted someone to check it before I send it to her. Too Many Minas Spoil The Con Dear Mina, I'm not quite sure how to start this letter. I feel as though I've failed a test of some kind and that if I only...

  4. Connector Generator (ConGen) Table of contents

    E-print Network

    Connector Generator (ConGen) Table of contents 1 Overview of Con of ConGen Software connectors are typically used in component-based engineering to model and realize component interconnections. Connectors play an important role both at design time, when they allow

  5. Combinando multiples discretizadores para aprendizaje de reglas evolutivo con enfoque

    E-print Network

    Bacardit, Jaume

    resultados de las pruebas realizadas con diversos dominios muestran que se consigue obtener un sistema clasi sistemas GABIL [3] y XCS [4] respectivamente. Para tratar con problemas con atributos reales una de las representaciones del conocimiento clasicas de este tipo de sistemas. Un buen algorit­ mo de discretizacion tiene

  6. Análisis comparado de los contratos marco para operaciones con derivados

    Microsoft Academic Search

    Iván Eduardo Rozo; Lina Maria Contreras; Laura Maria Gallego

    2010-01-01

    En teoría, las operaciones con derivados son instrumentos financieros cuyo propósito es cubrir los riesgos sobre los flujos a recibir, no obstante un contrato de esta naturaleza que presente vacíos o no cuente con provisiones suficientes, puede generar riesgos adicionales y costos de transacción aún mayores a los que se intentaba mitigar inicialmente. De acuerdo con lo anterior, este documento

  7. Energy Star program benefits Con Edison

    SciTech Connect

    NONE

    1995-05-01

    Impressed with savings in energy costs achieved after upgrading the lighting and air conditioning systems at its Manhattan headquarters, Home Box Office (HBO) wanted to do more, James Flock, vice president for computer and office systems, contacted Con Edison Co. of New York in March 1991 to determine what the company could do to save money by reducing energy consumed by personal computers. Arthur Kressner, Con Edison Research and Development manager contacted industry organizations and manufacturers for advice, but was told only to shut off computers at night and on weekends. Kressner arranged a series of meetings with IBM and the Electric Power Research Institute (EPRI) to discuss the issue, then approached the U.S. Environmental Protection Agency (EPA), which was designing a program to promote the introduction and use of energy-efficient office equipment. In 1992, the EPA announced the Energy Star program for PCs, enabling manufacturers to display the Energy Star logo on machines meeting program criteria, including the ability to enter a sleep mode in which neither the computer nor monitor consume more than 30 W or electricity. Industry experts estimate national energy consumption by office equipment could double by the year 2000, but Energy Star equipment is expected to improve efficiency and help maintain electric loads.

  8. Tiene familiares con Alzheimer? La Escuela de Medicina del Recinto de Ciencias Mdicas en colaboracin con la Universidad de Columbia

    E-print Network

    Quirk, Gregory J.

    ¿Tiene familiares con Alzheimer? 25/1/2008 La Escuela de Medicina del Recinto de Ciencias Médicas más con Alzheimer para participar de un estudio genético. La investigación pretende encontrar genes que se encuentren relacionados a la enfermedad de Alzheimer con el propósito de aprender más sobre las

  9. Web Spoofing: An Internet Con Game

    NSDL National Science Digital Library

    Balfanz, Dirk .

    1996-01-01

    The Safe Internet Programming group at the Princeton University Department of Computer Science in 1996 published a paper on the practice known as "web spoofing," through which an attacker intervenes between an end-user browsing the Web and real Web sites. The attacker sets up a shadow copy of the Web, and as users request pages from sites they will receive pages from the attacker's site instead. This process also enables attackers to gather data (possibly credit card numbers, etc.) submitted through bogus web forms. The nine-page paper describes how the con game works and suggests remedies. The article is available in PostScript, compressed PostScript, Microsoft Word, and zipped Microsoft Word format. Unfortunately, it is not available online as HTML.

  10. ConChord: Cooperative SDSI Certificate Storage and Name Resolution

    Microsoft Academic Search

    Sameer Ajmani; Dwaine E. Clarke; Chuang-hue Moh; Steven Richman

    2002-01-01

    We present ConChord, a large-scale certicate distribution system built on a peer-to-peer distributed hash table. ConChord provides load-balanced storage while eliminating many of the administrative dif- culties of traditional, hierarchical server architectures. ConChord is specically designed to support SDSI, a fully-decentralized public key infrastructure that allows principals to dene local names and link their namespaces to delegate trust. We discuss

  11. A ConA-like lectin from Dioclea guianensis Benth. has antifungal activity against Colletotrichum gloeosporioides, unlike its homologues, ConM and ConA.

    PubMed

    Araújo-Filho, José H; Vasconcelos, Ilka M; Martins-Miranda, Aparecida S; Gondim, Darcy M F; Oliveira, José T A

    2010-04-14

    This study reports on the antifungal activity of Dgui, a ConA-like lectin from Dioclea guianensis seeds. Dgui inhibited conidial germination but not mycelial growth of Colletotrichum gloeosporioides. The lectins ConA and ConM from Canavalia ensiformis and Canavalia maritima, respectively, share high levels of amino acid sequence similarity (>84%) with Dgui and have the same specificity toward glucose/mannose but had no effect on the fungus. Fluorescence microscopy showed that both Dgui and ConM bind to C. gloeosporioides ungerminated conidia. However, Dgui did not bind to C. gloeosporioides germinated conidia and germ tubes and was not inhibitory to mycelial growth. Because only Dgui inhibited germination of the fungus, C. gloeosporioides conidia might have surface-specific germination targets recognized by Dgui but not by its homologues, ConM and ConA. Therefore, Dgui is a candidate for biotechnological approaches for improving the resistance of various nutritionally and commercially important crops that are affected by C. gloeosporioides. PMID:20201549

  12. Breath Analysis Science at PittCon 2012, Orlando, Florida

    EPA Science Inventory

    Breath analysis science was featured in three organized sessions at this year?s Pittsburgh Conference and Exposition, or ?PittCon 2012? (http://www.pittcon.org/). As described in previous meeting reports, PittCon is one of the largest international conferences for analytical chem...

  13. -okfl ^ ORNL/CON-172 Linear Harmonic Analysis of Free-

    E-print Network

    Oak Ridge National Laboratory

    -okfl ^ ORNL/CON-172 OAK RIDGE NATIONAL LABORATORY Linear Harmonic Analysis of Free- Piston. #12;ORNL/CON-172 Engineering Technology Division* LINEAR HARMONIC ANALYSIS OF FREE-PISTON STIRLING/dynamic problem that is associated with a free-piston Stirling engine (FPSE). The governing equations

  14. VARIABILIDAD DE UN DIFRASISMO MAYA : EMPAREJAMIENTOS CON CH'AB

    E-print Network

    Boyer, Edmond

    VARIABILIDAD DE UN DIFRASISMO MAYA : EMPAREJAMIENTOS CON CH'AB JEAN-MICHEL HOPPAN* Y EMILIE por el análisis de la literatura maya previa al período de la conquista española1 aparece en forma de, propio de los mayas, consiste en el emparejamiento de un glifo que se lee ch'ab con otro que se lee ak

  15. Clave de determinacin de los Heliconiinae con rayas anaranjadas

    E-print Network

    Joron, Mathieu

    : mathieu.joron@ed.ac.uk 1. a. Abdomen con puntos amarillos y gruesos en los costados (intrasegmentales..............................................................................2 2. a. Abdomen con anillos intersegmentales amarillos........................Heliconius xanthocles relativamente pequeña, abdomen no muy largo. Ciertas razas no tienen color anaranjado en la cara dorsal

  16. iCons, 2011 Alzheimers and Aluminum: Lesson Plan

    E-print Network

    Auerbach, Scott M.

    © iCons, 2011 Alzheimers and Aluminum: Lesson Plan Handouts to explore mechanistic link between Alzheimer's and aluminum 5. Brief proposal expanding Points to Aluminum's Link With Alzheimer's Disease" from 1989. Provide handout

  17. Each year Minnesota Agricultural Experiment Station scientists con-

    E-print Network

    Minnesota, University of

    October. Plots at Rosemount and Roseau had hail at mid-season, which reduced yields. Tables 1 to 4 provide, Rosemount, Stewart, Wabun and Waseca. Tables 15 to 17 present SCN infor- mation from greenhouse tests con

  18. ConFunc - functional annotation in the twilight zone

    Microsoft Academic Search

    Mark N. Wass; Michael J. E. Sternberg

    2008-01-01

    Motivation: The success of genome sequencing has resulted in many protein sequences without functional annotation. We present ConFunc, an automated Gene Ontology (GO)-based protein function prediction approach, which uses conserved residues to generate sequence profiles to infer function. ConFunc split sets of sequences identified by PSI-BLAST into sub-alignments according to their GO annotations. Conserved residues are identified for each GO

  19. Breath analysis science at PittCon 2012, Orlando, Florida

    Microsoft Academic Search

    Joachim D Pleil; Matthew A Stiegel; Tzipporah M Kormos; Jon R Sobus

    2012-01-01

    BackgroundBreath analysis science was featured in three organized sessions at this year's Pittsburgh Conference and Exposition, or 'PittCon 2012' (http:\\/\\/www.pittcon.org\\/). As described in previous meeting reports, PittCon is one of the largest international conferences for analytical chemistry and instrumentation, typically attracting about 20 000 attendees and 1000 commercial exhibitors (Pleil 2010, 2011). This year the conference was held in Orlando,

  20. EFFECT OF CYPERMETHRIN ON CLINICO-HAEMATOLOGICAL PARAMETERS IN RABBITS

    Microsoft Academic Search

    M. KAMAL SHAH; A. KHAN; F. RIZVI; M. SIDDIQUE

    The aim of this study was to know the clinical and haematological changes in female rabbits following the treatment with cypermethrin (CY). In this study, 24 female rabbits were divided randomly into four equal groups A, B, C and D. Groups A, B and C were injected intraperitoneally CY @ 25, 50 and 75 mg\\/Kg b. wt., respectively, while the

  1. Primary brainstem death: a clinico-pathological study.

    PubMed Central

    Ogata, J; Imakita, M; Yutani, C; Miyamoto, S; Kikuchi, H

    1988-01-01

    A case of primary brainstem death in a man with surgically treated cerebellar haemorrhage is reported. Necropsy revealed extensive necrosis confined to the brainstem and cerebellum. The absence of diabetes insipidus and the persistence of electroencephalographic activity were the characteristic clinical features of the case. This differentiates the condition from so-called "whole brain death". Analysis of three further cases with acute vascular lesions of the brainstem or cerebellum, shown at necropsy, revealed that primary brainstem death with prolonged somatic survival can occur in specific circumstances after surgical intervension. Images PMID:3404164

  2. EPIDEMIOLOGICAL AND CLINICO-THERAPEUTIC STUDIES OF STRONGYLOSIS IN ELEPHANTS

    Microsoft Academic Search

    K. Suresh; P. C. Choudhuri; K. Nalini Kumari; P. A. Hamza

    Elephants like other herbivores are susceptible to various diseases including internal parasitism. In Nehru Zoological Park (NZP), Hyderabad, clinical records of Asian Elephants for a period of 10 years (1987-1996) were examined to determine the percent incidence of strongylosis in relation to season, age and sex. Faecal samples from elephants of S.V. Dairy Farm (SVD), Tirupathi were also screened from

  3. Two siblings with cortical dysplasia: Clinico-electroencephalographic features.

    PubMed

    Fukasawa, Tatsuya; Kubota, Tetsuo; Negoro, Tamiko; Maruyama, Shinsuke; Honda, Ryoko; Saito, Yuko; Itoh, Masayuki; Kakita, Akiyoshi; Sugai, Kenji; Otsuki, Taisuke; Kato, Mitsuhiro; Natsume, Jun; Watanabe, Kazuyoshi

    2015-06-01

    The older of two siblings began to have spasms and partial seizures at 1 month of age. Head magnetic resonance imaging showed an abnormal area in the left temporo-parieto-occipital region. Interictal electroencephalogram (EEG) showed a suppression-burst pattern. Adrenocorticotropic hormone stopped the spasms, but the seizures continued. Clonazepam, carbamazepine, zonisamide, and clobazam were ineffective. She underwent focal resection at age 8 months. Postoperatively, the seizures disappeared. Histopathologically, the lesion appeared to be focal cortical dysplasia type IIa. The younger sibling had spasms from birth. Head magnetic resonance imaging showed left hemi-megalencephaly. Interictal EEG showed a suppression-burst pattern. Phenobarbital, valproic acid, and zonisamide were ineffective. He underwent hemispherotomy at age 2 months and became seizure free. The histopathological features were consistent with those of hemi-megalencephaly. The siblings' EEG and clinical courses had some similarities. These siblings' conditions may have the same genetic background. PMID:26012518

  4. A clinico-pathological study of chronic hereditary motor neuropathy

    Microsoft Academic Search

    S. Matsubara; H. Tanabe

    1983-01-01

    Forty cases of chronic hereditary motor neuropathy (CHMN) were divided into five categories according to the distribution of muscle atrophy; they were proximal, facioscapulohumeral, bulbospinal, distal and scapuloperoneal forms. Their clinical features and laboratory data were analysed, and muscle biopsies from 32 of them were studied by histological, histochemical and electron microscopical methods. An attempt at quantitative assessment of the

  5. Clinico-pathological study of lymph node involvement in leprosy.

    PubMed

    Kar, H K; Mohanty, H C; Mohanty, G N; Nayak, U P

    1983-10-01

    One hundred and five leprosy patients including 37 cases of LL and LI, 22 cases of BL, 3 cases of BB, 17 cases of BT, 23 cases of TT and 3 cases of indeterminate type during the period of 1980-81 have been examined clinically. All the patients of LL, LI, BL and BB types, 94% of BT, 70% of TT and 66.6% of indeterminate type have showed clinical enlargement of lymph nodes. In order of frequency the enlarged nodes are inguinal (76.2%) cervical (69.5%), axillary (69.5%), epitrochlear (64.7%) and lastly pre-auricular (9.5%). Although both regional and distant groups of lymph node enlargement have been observed in all cases of LL, LI and BL, in majority of the non-lepromatous cases there is only involvement of regional lymph nodes. Biopsies of lymph nodes are made from 51 leprosy patients, 22 from LL and LI cases, 11 from BL cases, 2 from BB cases, 8 from BT cases, 6 from TT cases and 2 from indeterminate leprosy cases. Major histopathological changes have been studied in different types of leprosy. The humoral antibody response and the cellular immune response are well reflected on the histopathological finding of the lymph nodes belonging to different immunological spectrum of leprosy patients. The examination of lymph nodes is recommended as a useful adjunct for the diagnosis and classification of leprosy. PMID:6668933

  6. Vasculitides with cutaneous expression in children: clinico-pathological correlations.

    PubMed

    Borroni, G; Grassi, S; Carugno, A

    2015-02-01

    The most recent pediatric vasculitis classifications (EULAR/PRINTO/PRES) have proposed the use of an integration of clinical signs and symptoms, laboratory data, imaging and pathologic data. Pediatric vasculitis represent a peculiar clinical-diagnostic model, compared to the corresponding adult pathology chapter, and in particular, dermatopathologic aspects of these diseases identify more specific issues, made contingent by crucial variables such as duration of vasculitis lesion, site of the biopsy, proper biopsy depth, and possibility to correlate histopathological findings with immunopathological results. Possible additional diagnostic difficulties may arise from the fact that, in children, the same systemic disease, such as lupus erythematosus, may present with different clinical manifestations, with histopathological features of a precise type of vasculitis specific for that type of clinical manifestation. Examples are provided by hypocomplementemic urticarial vasculitis, cryoglobulinemic purpura, lymphocytic vasculitis of livedoid lesions. This paper describes the cutaneous histopathological findings of some vasculitis related pediatric diseases, be they pertaining to a systemic vasculitis with corresponding cutaneous vasculitis, to a systemic vasculitis with sporadic cutaneous vasculitic involvement, and to a systemic vasculitis without cutaneous vasculitic involvement. Type and level of histopathological vasculitic involvement, caliber of the vessel, type of vasculitis associated infiltrate, are likewise reliable integration in the complex diagnostic path of vasculitis in childhood. On the basis of these criteria dermatopathologists should be confident in identifying the type of the vasculitis and relate them to a specific pediatric disease. PMID:25516220

  7. [Lung infections in acquired immunodeficiency. Clinico-radiologic correlations].

    PubMed

    Cecconi, L; Busi Rizzi, E; Mazzuoli, G; Schininà, V

    1994-05-01

    Over the last decade the number of subjects with acquired immunodeficiencies has markedly increased; this phenomenon depends on both the large number of patients receiving organ transplants or antiblastic therapy and the spread of infections caused by the HIV virus. In 70-90% of these patients primary diseases include different pulmonary infections, relative to the type and degree of immune compromission. Pathogenic or, in most cases, opportunistic germs are responsible for severe pneumonia whose mortality rate can top 50%. Since prognosis depends on the promptness of treatment, the diagnosis of nature must be made quickly by integrating clinical and diagnostic findings with laboratory and instrumental results. Conventional chest radiology plays a major role as the first step in a diagnostic iter which can now include rather sensitive techniques--e.g., equalized chest films. CT and nuclear medicine often represent the necessary diagnostic complements but, in some cases, etiology can be diagnosed only with such invasive procedures as lung biopsy. The authors reviewed the current data on the diagnostic imaging findings of pulmonary infections caused by common germs, by Pneumocystis carinii mycobacteria, mycetes and viruses in immunocompromised patients, integrating their personal experience with literature data. PMID:8209024

  8. Cowden syndrome- Clinico-radiological illustration of a rare case

    PubMed Central

    Patil, Prashant B.; Sreenivasan, V.; Goel, Sumit; Nagaraju, K.; Vashishth, Shirin; Gupta, Swati; Garg, Kanika

    2013-01-01

    Cowden syndrome (CS) or multiple hamartoma syndrome is an infrequent genodermatoses, which is inherited as an autosomal dominant trait resulting from the mutation in the Phosphatase and Tensin homolog gene on the arm 10q and is principally characterized by multiple hamartomas with an increased risk of development of malignancies. Facial and oral signs are remarkable in the form of multiple papules and trichilemmomas on the face. We report one such rare case of CS in a 19-year-old patient who was diagnosed on the basis of her oral mucosal lesions and was further investigated and diagnosed with other hamartomas. The present case report signifies the responsibility of the oral physician in the early diagnosis of this progressive pathological syndrome as it leaves its footmark in the oral cavity in the form of oral mucosal lesions. PMID:23853470

  9. Número de autopsias clínicas y correlación clinico-patológica

    Microsoft Academic Search

    Josep Antoni Bombí

    2004-01-01

    SUMMARY Autopsy rate has dramatically decreased last decades all over the world. Based on our experience and reviewing the literature of the last twenty years we analyze this decline of the autopsy rate and the possibilities to improve. The concordance\\/discordance between cli- nical and pathological diagnosis based on published reports is also studied. All these data demonstrate that clinical autopsy

  10. Crystal structure of a lectin from Canavalia maritima (ConM) in complex with trehalose and maltose reveals relevant mutation in ConA-like lectins

    Microsoft Academic Search

    Plínio Delatorre; Bruno A. M. Rocha; Carlos A. A. Gadelha; Tatiane Santi-Gadelha; João B. Cajazeiras; Emmanuel P. Souza; Kyria S. Nascimento; Valder N. Freire; Alexandre H. Sampaio; Walter F. Azevedo; Benildo S. Cavada

    2006-01-01

    The crystal structure of Canavalia maritima lectin (ConM) complexed with trehalose and maltose revealed relevant point mutations in ConA-like lectins. ConM with the disaccharides and other ConA-like lectins complexed with carbohydrates demonstrated significant differences in the position of H-bonds. The main difference in the ConM structure is the replacement of Pro202 by Ser202, a residue that promotes the approximation of

  11. PROPUESTA DEL PROGRAMA Este grupo cuenta con 30 personas con un fin comun, el aporte al desarrollo de

    E-print Network

    de la matem´atica, en particular de los sistemas din´amicos en el Uruguay. Se ha separado la parte´ian particicipado de la pr´actica de la matem´atica en el Uruguay con un grupo de j´ovenes estudiantes que hab actividad, este grupo se ha consolidado como el mayor grupo de estudio de la matem´atica en el Uruguay, con

  12. Blond Blintz Bulletin Special Zebra-Con Edition 1

    E-print Network

    Multiple Contributors

    1979-01-01

    CON REPOR by Paulie Gi lmore Zebra Con Has hel d at t he Helrose Park Hol iday Inn . July 21. 28, and 29. and ~ras attended by about 60 of t he 65 people scheduled to come. ~re als Here proudly .... upported by 35 others. I suppose should take...'s over for now. Time to go ome ,:r .t .: GHOST CRIES by Febra Jean Ulch [i J]otty llil]ierison It was a quiet and peaceful place, nob like a park-than a cenetery' A s,nrff-ero;o "t=oapf"'rpful;;h;A ,i.-C*ripf"d ,gravesi.*- . Thpre wgre...

  13. Dia internacional de la dona Exposicin "Trabajo social con las mujeres" Pgina 1 de 2

    E-print Network

    Escolano, Francisco

    al.]. El apoyo social de mujeres solas con responsabilidad familiar: un estudio con madres usuariasDia internacional de la dona ­ Exposición "Trabajo social con las mujeres" Página 1 de 2 SELECCIÓN DE LIBROS PARA LA EXPOSICIÓN "TRABAJO SOCIAL CON LAS MUJERES" Alemán Bracho, Carmen, García Serrano

  14. Una gua de navegacin para las familias de Wisconsin con nios y

    E-print Network

    Wisconsin at Madison, University of

    Una guía de navegación para las familias de Wisconsin con niños y jóvenes con necesidades especiales de salud y discapacidades. GUÍA DE RECURSOS #12;#12;1 GUÍA DE RECURSOS Una guía de navegación para las familias de Wisconsin con niños y jóvenes con necesidades especiales de salud y discapacidades

  15. Detail of conning tower atop the submarine. Note the wire ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of conning tower atop the submarine. Note the wire rope wrapped around the base of the tower, which may have been used in an attempt to pull the submarine offshore. - Sub Marine Explorer, Located along the beach of Isla San Telmo, Pearl Islands, Isla San Telmo, Former Panama Canal Zone, CZ

  16. FUNCIONES CONTINUAS CON MAXIMOS LOCALES DENSOS GODOFREDO IOMMI

    E-print Network

    Iommi, Godofredo

    FUNCIONES CONTINUAS CON M´AXIMOS LOCALES DENSOS GODOFREDO IOMMI Abstract. En estas notas estudiaremos la clase de funciones continuas que poseen m´aximos estrictos locales en un conjunto denso. Siguiendo el trabajo de Posey y Vaughan construiremos un ejemplo expl´icito de una funci´on que pertenece

  17. Cómo hacer las gestiones con su plan de salud

    Cancer.gov

    Hay formas de saber si su plan de salud cubre los costos de atención médica de rutina durante un estudio clínico. Esta información puede servirle para saber con quién comunicarse para solicitar ayuda, preguntas que puede hacer y la información que debe recoger y guardar si decide participar en un estudio clínico.

  18. On Invariant Con guration of a Three-Fingered Grasp

    E-print Network

    Payandeh, Shahram

    using screw theory and inner product spaces. The results are shown to present themselves as an elegant advantage of the grasp con guration and the screw geometry. However, their method did not take advantage of the fundamental coordinate free property of screw systems and it was rather an algebraic approach. Various methods

  19. Real-time Coastal Observation Network (ReCON)

    E-print Network

    Real-time Coastal Observation Network (ReCON) The need for development of regional coastal. High bandwidth, wireless Ethernet-based system. Real-time, secure data access. Universal sensor real-time whole water column observations of physical, chemical, and biological variables. The Re

  20. performances, lectures, demonstra-tions, and workshops exploring con-

    E-print Network

    Miranda, Eduardo Reck

    promoted three major concerts in three different spaces. The opening event brought together the jazz of Frances Lynch, one of the few international singers to have worked closely with composers of electro- acoustic music. Her dramatic and most commited performances con- tinue to inspire many composers, not least

  1. Desarrollo costero y conservacin marina en armona con las personas

    E-print Network

    Richner, Heinz

    también explotan los recursos del mar pero que no se preocupan por el desarrollo sostenible. LaDesarrollo costero y conservación marina en armonía con las personas Los debates sobre la conservación marino costera El desarrollo y conservación de las costas de Costa Rica es concebido de formas

  2. 2006 Annual Report TAble of ConTenTS

    E-print Network

    Security Management and Assistance Security Testing and Metrics Security Technology Security Research, tests, and validation programs to promote, measure, and validate security in systems and services. WeComputer Security Division 2006 Annual Report #12;TAble of ConTenTS Welcome Letter Division

  3. Preserving con dentiality when sharing medical database the Cellsecu system

    E-print Network

    Chen, Sheng-Wei

    named Cellsecu that maintains not only the anonymity but also the con dentiality of each cell identi ers, such as name, address, and phone numbers. Simply removing all the explicit iden- ti ers, the existence of such database would enable researchers to track certain diseases as well as to patients

  4. Stochastic Con nement of Rossby Waves by Fluctuating Eastward Flows

    E-print Network

    Monahan, Adam Hugh

    Stochastic Con#12;nement of Rossby Waves by Fluctuating Eastward Flows Adam Hugh Monahan, Lionel axis - the so-called beta e#11;ect [20]. These planetary, or Rossby, waves have played an important of stationary Rossby waves on zonally- inhomogeneous ows such as the climatological boreal winter 300 mb ow

  5. con Diabetes Su diabetes s se puede controlar!

    E-print Network

    Do Well, Be Well con Diabetes ¡Su diabetes sí se puede controlar! Educational programs of the Texas, and the County Commissioners Courts of Texas Cooperating. to develop diabetes self-care skills, to improve eating habits and maintain good nutrition, to increase physical activity, to prevent diabetes complications

  6. L' ABUSO DI FARMACI NEL PAZIENTE CON CEFALEA: POSSIBILI INDICATORI

    Microsoft Academic Search

    PAOLA BROGGI; SANDRO IANNACCONE; LILIANA NOVELLA; STEFANO CLERICI; ANDREA FOSSATI; LUCIO SARNO

    L'abuso di farmaci tra le persone affette da disturbi cefalalgici rappresenta un problema di notevole rilevanza clinica, sia per il Medico di Medicina Generale (MMG), che frequentemente rappresenta il primo e unico inter- faccia con il paziente cefalalgico, sia per lo specialista Neurologo, che viene chiamato alla gestione di quadri clinici talora complessi. L'assunzione eccessiva o non congrua di alcuni

  7. Precisión de las velocidades radiales obtenidas con el REOSC

    NASA Astrophysics Data System (ADS)

    González, J. F.; Lapasset, E.

    Complementando una línea de trabajo iniciada con anterioridad discutimos la estabilidad del espectrógrafo REOSC de CASLEO en DC para la medición de velocidades radiales en base al análisis de observaciones realizadas en enero y abril de 1997. En esas oportunidades obtuvimos 26 espectros de estrellas patrones y 27 espectros de 3 estrellas usadas como estrellas de referencia en nuestro programa de cúmulos abiertos. Además tomamos 26 espectros de crepúsculo con el telescopio en posiciones cubriendo el rango H=-4,+4 y ? =-90,+30. Mediante correlaciones cruzadas derivamos la velocidad de 19 órdenes en cada uno de estos espectros. En base a un análisis estadístico de los datos obtenidos discutimos la contribución de los distintos factores que afectan a la dispersión de lectura observada. En particular, la flexión del instrumento no introduciría errores significativos cuando se observa con masas de aire menores que 2.0. La dispersión de los valores de velocidad medidos para espectros de alta relación S/N de una misma estrella resultó del orden de 0.5 km/s. La comparación con los valores de velocidad publicados por distintos autores para las estrellas patrones no permite distinguir ninguna diferencia sistemática apreciable de las velocidades de CASLEO, siendo la media cuadrática de los residuos del orden de 1.0 km/s.

  8. Null alleles for salivary Concanavalin A-binding (Con A) and Po proteins at PRB2 and PRB4 loci

    Microsoft Academic Search

    E. A. Azen; E. Amberger

    1994-01-01

    Six closely linked PRP (proline-rich protein) genes code for many salivary PRPs which show frequent null variants especially. The Con polymorphism includes the different sized Con 1 and Con 2 proteins and the null Con 0 form. N-terminal amino acid sequences (60 aa) were determined on Con 1 and Con 2 proteins. From comparison of the protein sequences with those

  9. Expandiendo los límites del teatro: Una entrevista con Astrid Hadad

    E-print Network

    Alzate, Gastó n

    1997-04-01

    SPRING 1997 153 Expandiendo los límites del teatro: Una entrevista con Astrid Hadad Gastón Álzate Astrid Hadad, nacida en Chetumal, Quintana Roo (México) y de padres libaneses, es hoy en día una de las artistas más significativas dentro de un... consolidado un espacio propio. Esto se puede apreciar en el trabajo desarrollado por Jesusa Rodríguez, Liliana Felipe y la misma Astrid Hadad. Es importante anotar que existe un buen número de artistas que ha venido desarrollando trabajos paralelos, como es...

  10. Vibrational and rotational relaxation in a CON2 laser

    Microsoft Academic Search

    R. Charneau; F. Legay; N. Legay-Sommaire; G. Taieb

    1975-01-01

    A double-resonance method inside the optical cavity of a CO-N2 laser has been used to study vibrational and rotational relaxation processes in the amplifying medium. Measurements of rotational relaxation of CO are in agreement with the work of other authors. Measurements of the V-V exchange rates between two molecules in a high vibrational state (v approximately equal to 10) suggest

  11. Segundo Catálogo Estelar del Hemisferio Sur con Astrolabio Fotoeléctrico PAII

    NASA Astrophysics Data System (ADS)

    Manrique, W. T.; Podestá, R. C.; Alonso, E.; Actis, E. V.; Pacheco, A. M.; Bustos, G.; Lizhi, L.; Zezhi, W.; Fanmiao, Z.; Hongqi, W.; Perdomo, R.

    Recordamos que entre el Observatorio Astronómico ``Félix Aguilar'', el Observatorio Astronómico de Beijing y el Observatorio Astronómico de La Plata, se ha convenido en desarrollar un Proyecto de Investigación conjunto, para la observación sistemática de estrellas en el Hemisferio Sur, con el objeto de la elaboración de un Catálogo Estelar Global utilizando un Astrolabio Fotoeléctrico PAII del Observatorio de Beijing, que ha sido usado con éxito en la República de China. En este trabajo se presenta el Segundo Catálogo Estelar del Hemisferio Sur, derivado de las observaciones realizadas con el PAII instalado en el OAFA, durante el períiodo Febrero de 1992 a Marzo de 1997. En este lapso se han observado mas de 400000 pasajes estelares, obteniéndose las correcciones ? ? y ? ? de 5241 estrellas del FK4, FK5, FK5 Ext., SRS, CAMC y GC. Las precisiones medias son del orden de ± 3,2 ms en ascensión recta y ±0."057 en declinación. Rango de magnitudes : 2,0 a 11,5 Rango de declinaciones : -3o a -60o Epoca Media : 1994.9 Se analizan los residuos en función de la magnitud y tipo espectral, correcciones de grupo y frecuencia de distribución ? ? y ? ?.

  12. Crystal structure of a lectin from Canavalia maritima (ConM) in complex with trehalose and maltose reveals relevant mutation in ConA-like lectins.

    PubMed

    Delatorre, Plínio; Rocha, Bruno A M; Gadelha, Carlos A A; Santi-Gadelha, Tatiane; Cajazeiras, João B; Souza, Emmanuel P; Nascimento, Kyria S; Freire, Valder N; Sampaio, Alexandre H; Azevedo, Walter F; Cavada, Benildo S

    2006-06-01

    The crystal structure of Canavalia maritima lectin (ConM) complexed with trehalose and maltose revealed relevant point mutations in ConA-like lectins. ConM with the disaccharides and other ConA-like lectins complexed with carbohydrates demonstrated significant differences in the position of H-bonds. The main difference in the ConM structure is the replacement of Pro202 by Ser202, a residue that promotes the approximation of Tyr12 to the carbohydrate-binding site. The O-6' of the second glucose ring in maltose interacts with Tyr12, while in trehalose the interaction is established by the O-2' and Tyr12, explaining the higher affinity of ConM for disaccharides compared to monosaccharides. PMID:16677825

  13. Aspectos relacionados con la sexualidad y la reproducción –para profesionales de salud (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca de los factores que pueden afectar el funcionamiento sexual de las personas con cáncer. Se discuten además temas sobre la fecundidad relacionados con el tratamiento del cáncer.

  14. IZ-CON: an intelligent zone controller for building systems operation

    E-print Network

    Mahdavi, A.; Schub, M.

    2012-01-01

    This paper describes the concept of an intelligent zone controller (IZ-CON) for integrated operation of building systems. IZ-CON is intended to deploy a predictive control methodology with embedded simulation capability. Thereby, the scalability...

  15. IZ-CON: an intelligent zone controller for building systems operation 

    E-print Network

    Mahdavi, A.; Schub, M.

    2012-01-01

    This paper describes the concept of an intelligent zone controller (IZ-CON) for integrated operation of building systems. IZ-CON is intended to deploy a predictive control methodology with embedded simulation capability. Thereby, the scalability...

  16. El teatro como reflexión colectiva: Conversación con Sergio Corrieri

    E-print Network

    Luzuriaga, Gerardo

    1983-04-01

    gente del Escambray se nos queja. Uno de los aspectos más interesantes, a mi modo de ver, de la experiencia del Teatro Escambray es que todo este proceso se ha ido haciendo sobre la marcha, ha ido surgiendo, como tú decías hace poco, de la práctica... grandes rasgos, por supuesto. Por nuestra convivencia en la zona y por los multiples canales naturales que eso nos brinda, nosotros estamos actualizados de la problemática. Aparte, con el tiempo, el Escambray ha ido perdiendo artistas particulares en el...

  17. Apoyo a Estudios Geodinamicos con GPS en Guatemala

    NASA Astrophysics Data System (ADS)

    Robles, V. R.

    2013-05-01

    El Instituto Geografico Nacional de Guatemala implemento 17 estaciones GNSS en el año 2009, como un proyecto de credito mixto de donacion de equipamiento del Gobierno de Suiza, el cual, este equipamiento de estaciones CORS GNSS es un sistema de recepción y transmisión de datos crudos GPS RInex que utiliza la tecnologia Spider Web de Leica, asi mismo este sistema esta sirviendo para el espablecimiento de un marco geodesico nacional de coordenadas geodesicas oficiales, el cual se calculan u obtienen las velocidades en tiempos temporales programados de las 17 Estaciones CORS. La infraestructura del marco geodesico de Guatemala esta sirviendo de base para las aplicaciones de estudios geodinamicos como el monitoreo de del desplazamiento de las placas tectonicas por medio de un estudio que se inicio en el año de 1999, llamado medicion con GPS el sistema de Fallas de los rios Polochic Motagua de Guatemala, tambien para un estudio que se implemento para deformación de corteza terrestre local en un Volcan Activo de Guatemala llamado Pacaya. Para el estudio de medicion con GPS en el sistema de falla de los Rios del polochic Motagua se implementaron 16 puntos para medir con GPS de dos frecuencias en el año de 1999, el cual, tres puntos son estaciones geodesicas CORS IGS llamados GUAT, ELEN y HUEH, despues en el año de 2003 se hizo otra medicion en un total de 20 puntos, que permitió calcular las velocidades de desplazamieinto de los puntos en mención, usando como referencia el modelo NUVEL 1A de DeMets de la placa de Norteamerica. Este estudio fue en cooperación internacional por la universidad de Nice de Francia y el IGNde Francia. Para el estudio del monitoreo con GPS del volcan activo de Guatemala, se implementaron cuatro puntos al rededor del volcan, el cual, se realizan cuatro mediciones al año, que permiten determinar axialmente la distancias entre los puntos, y rebisar estadisticamente cual es el comportamiento de las distancias en funcion del tiempo, si existen diferencias graduales crecientes o decrecientes, que nos da un indicativo del desplazamiento de la corteza terrestre al rededor del volcan.

  18. Las espirales de Fibonacci podran estar relacionadas con la tensin 26/04/2007 Astroseti

    E-print Network

    Zexian, Cao

    Las espirales de Fibonacci podrían estar relacionadas con la tensión 26/04/2007 Astroseti Las espirales de Fibonacci podrían estar relacionadas con la tensión. La serie de Fibonacci ­ en la cual cada tensión" para crear espirales con la serie de Fibonacci en microestructuras que crecen en laboratorio

  19. Information Loss in Coarse Graining of Polymer Con gurations via Contact

    E-print Network

    - duced description of this system can be based [7, 10, 13, 14] on associating to each polymer con#12Information Loss in Coarse Graining of Polymer Con#12;gurations via Contact Matrices Patrik L description of the con- #12;guration ! of a linear chain (polymer or random walk) on Z n : C ij (!) = 1 when

  20. Trastorno por déficit de atención con hiperactividad: orientaciones psicoeducativas para los padres

    Microsoft Academic Search

    López Villalobos; S. Alberola López; José Antonio López Villalobos

    2008-01-01

    Resumen Se exponen orientaciones psicoeducativas para padres de niños con trastorno por déficit de atención con hiperactividad (TDAH), basadas en criterios empíricos, teóricos y clínicos, abor- dando las siguientes dimensiones: ambiente familiar, modelado, refuerzo de conducta, normas, autonomía y autoestima, aprender a pensar y saber esperar, atención, relación con compañeros, grupo familiar, adolescencia y una reflexión sobre el tratamiento. Palabras

  1. Sepsis por Salmonella enteritidis en una paciente con lupus eritematoso sistémico

    Microsoft Academic Search

    Carlos Alberto Cañas; Gustavo Adolfo Ospina; María Elena Ochoa; Juan Diego Vélez

    Resumen Presentamos el caso clínico de una paciente de 28 años de edad con Lupus Eritematoso Sistémico (LES), con compromiso a nivel neurológico central, riñón y sistema hematológico, con tratamiento cró- nico de esteroides y desnutrición avanzada, quien desarrolla sepsis por Salmonella enteritidis, germen aislado en muestras tomadas en lavado bronco alveolar, sangre y materia fecal. Presentó un absce- so

  2. Accesibilidad para personas con debilidad motriz ASIC 18 de noviembre de 2010 Pg. 1 de 7

    E-print Network

    Fernández de Córdoba, Pedro

    Accesibilidad para personas con debilidad motriz Windows XP ASIC ­ 18 de noviembre de 2010 Pág. 1: · Pulse T Utilizando el ratón #12;Accesibilidad para personas con debilidad motriz Windows XP ASIC ­ 18 de)... #12;Accesibilidad para personas con debilidad motriz Windows XP ASIC ­ 18 de noviembre de 2010 Pág. 3

  3. Accesibilidad para personas con debilidad visual ASIC 18 de noviembre de 2010 Pg. 1 de 6

    E-print Network

    Fernández de Córdoba, Pedro

    Accesibilidad para personas con debilidad visual Windows XP ASIC ­ 18 de noviembre de 2010 Pág. 1: · Pulse T #12;Accesibilidad para personas con debilidad visual Windows XP ASIC ­ 18 de noviembre de 2010 seleccionando las opciones adecuadas). #12;Accesibilidad para personas con debilidad visual Windows XP ASIC ­ 18

  4. Accesibilidad para personas con debilidad auditiva ASIC 18 de noviembre de 2010 Pg. 1 de 8

    E-print Network

    Fernández de Córdoba, Pedro

    Accesibilidad para personas con debilidad auditiva Windows 7 ASIC ­ 18 de noviembre de 2010 Pág. 1 sonidos. #12;Accesibilidad para personas con debilidad auditiva Windows 7 ASIC ­ 18 de noviembre de 2010 con debilidad auditiva Windows 7 ASIC ­ 18 de noviembre de 2010 Pág. 3 de 8 -Figura 1-Centro de

  5. COMPARACIÓN ENTRE LA TERAPIA CONVENCIONAL ODONTOLÓGICA Y SU USO COMBINADO CON LA FISIOTERAPIA Y LA OSTEOPATÍA, EN PACIENTES CON DISFUNCIÓN TEMPOROMANDÍBULAR. \\

    Microsoft Academic Search

    Graciela Carvallo; Maria Fasanella; Sofia Caricote

    RESUMEN Dado que la disfunción temporomandibular es una patología que cursa frecuentemente con, dolor y limitación en la apertura bucal los pacientes afectados reducen su calidad de vida desde el punto de vista social, laboral y familiar. La presente investigación tiene como propósito evaluar comparativamente los alcances terapéuticos entre el tratamiento odontológico convencional y el uso combinado de éste, con

  6. Do Well, Be Well with Diabetes 2013 1 Formulario de Registro para Personas con Diabetes Formulario de Registro para Personas con Diabetes 2013

    E-print Network

    Do Well, Be Well with Diabetes ­ 2013 1 Formulario de Registro para Personas con Diabetes Formulario de Registro para Personas con Diabetes ­ 2013 Si usted NO TIENE diabetes, por favor NO LLENE este sobre diabetes en el Condado de _______________. D. El código postal en mi casa es __ __ __ __ __. E

  7. Do Well, Be Well with Diabetes 2013 1 Formulario de Conclusin para Personas con Diabetes Formulario de Conclusin para Personas con Diabetes 201

    E-print Network

    Do Well, Be Well with Diabetes ­ 2013 1 Formulario de Conclusión para Personas con Diabetes Formulario de Conclusión para Personas con Diabetes ­ 201 Si usted NO TIENE diabetes, por favor NO LLENE este últimos cuatro números de mi número telefónico son __ __ __ __. C. Marque todas las clases sobre diabetes

  8. Amino Acid Synthesis from CO-N2 and CO-N2-H2 Gas Mixtures Via Complex Organic Compounds

    NASA Astrophysics Data System (ADS)

    Miyakawa, S.; Kobayashi, K.; Sawaoka, A. B.

    1999-01-01

    Reaction among hydrogen cyanide (HCN), formaldehyde (H2CO) and ammonia (NH3) are generally considered an important reaction in amino acid synthesis by electric discharge. Precursors of glycine and aspartic acid were, however, synthesized by adding water to metastable complex compounds produced by quenching a CO-N2 high-temperature plasma. In order to investigate effects of water remaining in an experimental vacuum chamber, optical emission spectroscopic and mass spectrometric measurements were conducted with CO-N2 and CO-N2-H2 gas mixtures. Although residual hydrogen atoms were detected in the CO-N2 experiment, the amount of them was much less than that in the CO-N2-H2 experiment

  9. [Modern tribology in total hip arthroplasty: pros and cons].

    PubMed

    Gómez-García, F

    2014-01-01

    The wear products and adverse reactions that occur on bearing surfaces represent one of the greatest challenges in prosthetic replacements, as the latter experience increasing demands due to the large number of young and older adult patients that have a long life expectancy and remarkable activity. The purpose of this review is to analyze the pros and cons of the new advances in the bearing components of the articular surfaces of current total hip arthroplasties. We also discuss the strategies used historically, their problems, results and the surgeon's role in prescribing the tribologic couple that best fits each patient's needs. We conclude with practical recommendations for the prescription and management of the latest articular couples for total hip arthroplasty. PMID:26021098

  10. Obtención de perfiles teóricos de elementos metálicos con velocidades macroscópicas

    NASA Astrophysics Data System (ADS)

    Cirigliano, D.; Costa, A.; Rovira, M.

    El propósito de este trabajo es poder establecer -a partir de la modelización de perfiles de distintas especies- patrones de comparación observacional que permitan caracterizar los fenómenos físicos que están presentes en las estructuras que se observan. Para ello se resuelven las ecuaciones de equilibrio de ionización para un determinado átomo y una atmósfera de parámetros determinados. A partir de ello se definen las poblaciones para los distintos grados de ionización. Considerando distintas configuraciones e intensidades de flujos de masa se deducen la función fuente, el espesor óptico y se calculan los perfiles de las distintas líneas. Se obtuvieron perfiles teóricos de líneas del CII, CIV y del OIV para flujos entrante, saliente y pasante. La forma del perfil, las intensidades relativas entre los distintos flujos y el corrimiento Doppler da cuenta de una caracterización teórica a partir de la cual se comparará con observaciones.

  11. Neogene sequence stratigraphy, Nam Con Son Basin, offshore Vietnam

    SciTech Connect

    McMillen, K.J. [Beaver Creek Tech. Co., Mason, TX (United States); Do Van Luu; Lee, E.K.; Hong, S.S. [PEDCO, Ho Chi Minh City (Viet Nam)

    1996-12-31

    An integrated well log, biostratigraphic, and seismic stratigraphic study of Miocene to Recent deltaic sediments deposited in the Nam Con Son Basin offshore from southern Vietnam shows the influence of eustacy and tectonics on sequence development. Sediments consist of Oligocene non-marine rift-basin fill (Cau Formation), early to middle Miocene tide-dominated delta plain to delta front sediments (TB 1.5 to TB 2.5, Due and Thong Formations), and late Miocene to Recent marine shelf sediments (TB. 2.6 to TB 3.1 0, Mang Cau, Nam Con Son, and Bien Dong Formations). Eustacy controlled the timing of key surfaces and sand distribution in the tectonically-quiet early Miocene. Tectonic effects on middle to late Miocene sequence development consist of thick transgressive systems tracts due to basin-wide subsidence and transgression, sand distribution in the basin center, and carbonate sedimentation on isolated fault blocks within the basin. Third-order sequence boundaries (SB) are identified by spore peaks, sand stacking patterns, and channel incision. In the basin center, widespread shale beds with coal occur above sequence boundaries followed by transgressive sandstone units. These TST sandstones merge toward the basin margin where they lie on older HST sandstones. Maximum flooding surfaces (MFS) have abundant marine microfossils and mangrove pollen, a change in sand stacking pattern, and often a strong seismic reflection with downlap. Fourth-order genetic-type sequences are also interpreted. The MFS is the easiest marker to identify and correlate on well logs. Fourth-order SB occur within these genetic units but are harder to identify and correlate.

  12. Neogene sequence stratigraphy, Nam Con Son Basin, offshore Vietnam

    SciTech Connect

    McMillen, K.J. (Beaver Creek Tech. Co., Mason, TX (United States)); Do Van Luu; Lee, E.K.; Hong, S.S. (PEDCO, Ho Chi Minh City (Viet Nam))

    1996-01-01

    An integrated well log, biostratigraphic, and seismic stratigraphic study of Miocene to Recent deltaic sediments deposited in the Nam Con Son Basin offshore from southern Vietnam shows the influence of eustacy and tectonics on sequence development. Sediments consist of Oligocene non-marine rift-basin fill (Cau Formation), early to middle Miocene tide-dominated delta plain to delta front sediments (TB 1.5 to TB 2.5, Due and Thong Formations), and late Miocene to Recent marine shelf sediments (TB. 2.6 to TB 3.1 0, Mang Cau, Nam Con Son, and Bien Dong Formations). Eustacy controlled the timing of key surfaces and sand distribution in the tectonically-quiet early Miocene. Tectonic effects on middle to late Miocene sequence development consist of thick transgressive systems tracts due to basin-wide subsidence and transgression, sand distribution in the basin center, and carbonate sedimentation on isolated fault blocks within the basin. Third-order sequence boundaries (SB) are identified by spore peaks, sand stacking patterns, and channel incision. In the basin center, widespread shale beds with coal occur above sequence boundaries followed by transgressive sandstone units. These TST sandstones merge toward the basin margin where they lie on older HST sandstones. Maximum flooding surfaces (MFS) have abundant marine microfossils and mangrove pollen, a change in sand stacking pattern, and often a strong seismic reflection with downlap. Fourth-order genetic-type sequences are also interpreted. The MFS is the easiest marker to identify and correlate on well logs. Fourth-order SB occur within these genetic units but are harder to identify and correlate.

  13. Con A-induced suppressor cells in children with acute lymphoblastic leukaemia.

    PubMed Central

    Eibl, M; Krepler, P; Schmidmeier, W; Zielinski, C; Winterleitner, H

    1980-01-01

    The function of Con A stimulation was investigated in patients with ALL in remission and in patients with ALL in the acute phase of the disease as compared to healthy controls. Suppression of the Con A response brought about by autologous Con A-activated cells was significantly lower in ALL patients in remission (mean value 29.33%) and in the acute phase (mean value 10%) than in the controls (mean value 64.86%). Suppression of the Con A stimulation of control lymphocytes by Con A-activated homologous cells of ALL patients had a mean value of 51.65%. This was significantly higher than the suppression obtained by the same ALL cells in the autologous system and of the same order of magnitude as the suppression obtained by control Con A-activated cells on control Con A stimulation (57.67%). Suppression of the Con a response of ALL lymphocytes produced by control Con A-activated cells was 23.17% and comparable to healthy controls. These results demonstrate that the function of Con A-induced suppression is significantly lower in ALL patients. They further indicate that at least two cell types are involved in this kind of suppression in humans. PMID:6448114

  14. Range Con: a management evaluation system for assessing sucess of selected range improvement practices

    E-print Network

    Ekblad, Steven Linn

    1989-01-01

    Knowledge Representation Procedure. Knowledge Acquisition Procedure. Validation Procedure. 12 15 20 Modeling Qualitative Judgement. 22 TABLE OF CONTENTS Continued DEVELOPMENT OF RANGE CON. Phase 1 ? Prototype Phase 2 ? Prototype. Range Con... System Planning Model 2. Range Con knowledge acquisition and knowledge- base flow chart development procedure. 17 3. Algorithm for combination of rule certainty factors in inexact reasoning model (adapted from Buchanan and Shortliffe 1985) 24 4...

  15. Pros, Cons, and Alternatives to Weight Based Cost Estimating

    NASA Technical Reports Server (NTRS)

    Joyner, Claude R.; Lauriem, Jonathan R.; Levack, Daniel H.; Zapata, Edgar

    2011-01-01

    Many cost estimating tools use weight as a major parameter in projecting the cost. This is often combined with modifying factors such as complexity, technical maturity of design, environment of operation, etc. to increase the fidelity of the estimate. For a set of conceptual designs, all meeting the same requirements, increased weight can be a major driver in increased cost. However, once a design is fixed, increased weight generally decreases cost, while decreased weight generally increases cost - and the relationship is not linear. Alternative approaches to estimating cost without using weight (except perhaps for materials costs) have been attempted to try to produce a tool usable throughout the design process - from concept studies through development. This paper will address the pros and cons of using weight based models for cost estimating, using liquid rocket engines as the example. It will then examine approaches that minimize the impct of weight based cost estimating. The Rocket Engine- Cost Model (RECM) is an attribute based model developed internally by Pratt & Whitney Rocketdyne for NASA. RECM will be presented primarily to show a successful method to use design and programmatic parameters instead of weight to estimate both design and development costs and production costs. An operations model developed by KSC, the Launch and Landing Effects Ground Operations model (LLEGO), will also be discussed.

  16. Non Invasive Biomedical Analysis. Breath Networking Session at PittCon 2011, Atlanta, Georgia Non Invasive Biomedical Analysis. Breath Networking Session at PittCon 2011, Atlanta, Georgia

    Microsoft Academic Search

    Joachim D. Pleil

    2011-01-01

    Background This was the second year that our breath colleagues organized a networking session at the Pittsburgh Conference and Exposition, or 'PittCon' (www.pittcon.org\\/). This time it was called 'Non Invasive Biomedical Analysis' to broaden the scope a bit, but the primary focus remained on exhaled breath diagnostics. As reported last year in the Journal of Breath Research, PittCon continues to

  17. MEETING REPORT Breath Biomarkers Networking Sessions at PittCon 2010, Orlando, Florida Breath Biomarkers Networking Sessions at PittCon 2010, Orlando, Florida

    Microsoft Academic Search

    Joachim D. Pleil

    2010-01-01

    The Pittsburgh Conference and Exposition, or 'PittCon' (www.pittcon.org\\/), is one of the largest international conferences for analytical chemistry and instrumentation, typically attracting about 25 000 attendees and 1000 commercial exhibitors. PittCon began in 1950 as a small spectroscopy and analytical chemistry gathering and, as the name implies, originated in Pittsburgh, PA. The conference has outgrown its humble beginnings and is

  18. Un programa innovador busca ayudar a las personas que cuidan a pacientes con cáncer

    Cancer.gov

    Los familiares proporcionan la gran mayoría de los cuidados de las personas con cáncer. Un programa educativo del City of Hope Cancer Center ofrece a los profesionales de salud la información y las herramientas necesarias para ayudar a los familiares a saber cómo cuidarse a si mismos y a sus seres queridos con cáncer.

  19. EL RAZONAMIENTO PROPORCIONAL EN ALUMNOS DE 7º GRADO CON DIFERENTES EXPERIENCIAS CURRICULARES 1

    Microsoft Academic Search

    David Ben-Chaim; James Fey; William Fitzgerald; Catherine Benedetto; Jane Miller

    Se presentaron problemas contextualizados que envuelven números racionales y razonamiento proporcional a alumnos de 7° con diferentes experiencias curriculares. Hay fuerte evidencia de que los estudiantes en la reforma curricular, quienes son estimulados a construir sus propios conceptos y procedimientos de proporcionalidad a través de trabajo colaborativo de resolución de problemas, tuvieron un mejor desempeño que los estudiantes con un

  20. Control contextual en el aprendizaje de números para un niño con discapacidad intelectual

    Microsoft Academic Search

    Francisco J. Alós

    2007-01-01

    El objetivo de este estudio fue la enseñanza de la discriminación «igual» y «diferente» en números. Se describe un experimento efectuado con un niño de siete años con discapacidad intelectual. El proble- ma fue analizado desde la perspectiva del control contextual. El procedimiento de aprendizaje consis- tió en la enseñanza explícita de una discriminación condicional de segundo orden y se

  1. Per: Chirapaq celebra 25 aos con un foro sobre "Derechos de los Pueblos Indgenas"

    E-print Network

    Islas, León

    Perú: Chirapaq celebra 25 años con un foro sobre "Derechos de los Pueblos Indígenas celebrará su 25 aniversario con el foro público internacional: "Derechos de los Pueblos Indígenas: Avances y la Nación Cree, ex parlamentario y miembro del Mecanismo de Expertos sobre los Derechos de los

  2. Table of ConTenTs -Temp 2 Message from the President

    E-print Network

    Indiana University

    Cial RepoRT 2009­10 Table of ConTenTs 2 Message from the President 6 Message from the Vice President#12;#12;1 Table of ConTenTs -Temp 2 Message from the President 7 Message from the Vice President and Chief Financial Officer 9 Independent Auditors' Report 10 Management's Discussion and Analysis 18

  3. La salud en personas con discapacidad intelectual en España: estudio europeo POMONA-II

    PubMed Central

    Martínez-Leal, Rafael; Salvador-Carulla, Luis; Gutiérrez-Colosía, Mencía Ruiz; Nadal, Margarida; Novell-Alsina, Ramón; Martorell, Almudena; González-Gordón, Rodrigo G.; Mérida-Gutiérrez, M. Reyes; Ángel, Silvia; Milagrosa-Tejonero, Luisa; Rodríguez, Alicia; García-Gutiérrez, Juan C.; Pérez-Vicente, Amado; García-Ibáñez, José; Aguilera-Inés, Francisco

    2011-01-01

    Introducción Estudios internacionales demuestran que existe un patrón diferenciado de salud y una disparidad en la atención sanitaria entre personas con discapacidad intelectual (DI) y población general. Objetivo Obtener datos sobre el estado de salud de las personas con DI y compararlos con datos de población general. Pacientes y métodos Se utilizó el conjunto de indicadores de salud P15 en una muestra de 111 sujetos con DI. Los datos de salud encontrados se compararon según el tipo de residencia de los sujetos y se utilizó la Encuesta Nacional de Salud 2006 para comparar estos datos con los de la población general. Resultados La muestra con DI presentó 25 veces más casos de epilepsia y el doble de obesidad. Un 20% presentó dolor bucal, y existió una alta presencia de problemas sensoriales, de movilidad y psicosis. Sin embargo, encontramos una baja presencia de patologías como la diabetes, la hipertensión, la osteoartritis y la osteoporosis. También presentaron una menor participación en programas de prevención y promoción de la salud, un mayor número de ingresos hospitalarios y un uso menor de los servicios de urgencia. Conclusiones El patrón de salud de las personas con DI difiere del de la población general, y éstas realizan un uso distinto de los servicios sanitarios. Es importante el desarrollo de programas de promoción de salud y de formación profesional específicamente diseñados para la atención de personas con DI, así como la implementación de encuestas de salud que incluyan datos sobre esta población. PMID:21948011

  4. Resolution of Con icts Involving Many Aircraft via Semide nite Programming

    E-print Network

    Feron, Eric

    Resolution of Con icts Involving Many Aircraft via Semide nite Programming E. Frazzoli Z.-H. Mao y J.-H. Oh z E. Feron x April, 1999 Abstract Aircraft con ict detection and resolution is currently question: Given a set of airborne aircraft and their intended trajectories, what control strategy should

  5. CPR: A Con guration Pro ling Tool Srihari Cadambiand Seth Copen Goldsteiny

    E-print Network

    Goldstein, Seth Copen

    CPR: A Con guration Pro ling Tool Srihari Cadambiand Seth Copen Goldsteiny Carnegie Mellon tool CPR and show how it can be used to aid compiler designers, FPGA architects and in the con- struction of a macro-generator libraries. CPR uses subgraph matching to identify the parts of an ap

  6. Meeting Report: Breath Biomarkers Networking Sessions at PittCon 2010, Orlando, Florida

    EPA Science Inventory

    The Pittsburgh Conference and Exposition, or "PittCon" (www.pittcon.org/), is one of the largest international conferences for analytical chemistry and instrumentation typically attracting about 25,000 attendees and 1,000 commercial exhibitors. PittCon began in 1950 as a small sp...

  7. Teorías y doctrina sobre las relaciones del derecho con la economía

    Microsoft Academic Search

    William Leguizamón Acosta

    2004-01-01

    A partir de la conformación definitiva de la Economía como ciencia autónoma; hecho sucedido a partir de la obra de ADAM SMITH “sobre la naturaleza y riqueza de las Naciones” se ha venido discutiendo con intensidad sobre las estrechas relaciones que esta disciplina mantiene con el Derecho. Algunos abordan el tema bajo condiciones de dominio de una ciencia sobre la

  8. Resolving con icts in collaborative human-computer interaction (extended abstract)

    E-print Network

    Resolving con icts in collaborative human-computer interaction (extended abstract) Robert St. Amant softwareagentsand human agents. Our discus- sion is drawn mainly from research in human-computer interaction (HCI in autonomous agents research. Managing con icts in human-computer interaction poses a set of challenges beyond

  9. conStruction MAnAgeMent College of Rural and Community Development

    E-print Network

    Hartman, Chris

    conStruction MAnAgeMent College of Rural and Community Development Community and Technical College The construction management program meets growing needs in the con- struction industry by training entry-level construction managers and by providing continuing education for construction employees. Construction managers

  10. Taller de espacios de Banach Reticulos de Banach con la propiedad de Kato

    E-print Network

    Taller de espacios de Banach Reticulos de Banach con la propiedad de Kato Resumen: Se estudian retículos de Banach y espacios de funciones de reordenamiento invariante E con la propiedad de que las Estructura de Espacios de Banach (MTM2012-31286) Francisco L. Hernández UCM #12;

  11. Diventa Social Media Trainer Aumenta le tue possibilit occupazionali con competenze Web 2.0 e

    E-print Network

    Robbiano, Lorenzo

    Diventa Social Media Trainer · Aumenta le tue possibilità occupazionali con competenze Web 2.0 e marketing. Perché partecipare: · Riceverai una Formazione per diventare un Social Media Trainer formative, aiutando un membro dello staff aziendale a familiarizzare con gli strumenti Social Media. Questo

  12. On the Formal Veri cation of the TCAS Con ict Resolution Algorithms 1

    E-print Network

    Lynch, Nancy

    On the Formal Veri cation of the TCAS Con ict Resolution Algorithms 1 John Lygeros and Nancy Lynch 02139 lygeros, lynch@lcs.mit.edu Abstract TCAS is an on-board protocol for detecting con icts between aircraft and providing resolution advisories to the pilots. Because of its safety-critical role the TCAS

  13. Enhanced ballistic performance of conned multi-layered ceramic targets against long rod penetrators through

    E-print Network

    Espinosa, Horacio D.

    Enhanced ballistic performance of con®ned multi-layered ceramic targets against long rod Science Ltd. All rights reserved. Keywords: Ballistic penetration; Damage; Fragmentation; Interferometry is one of the most important material properties that in¯uence its ballistic performance and motivated

  14. Accesibilidad para personas con debilidad motriz ASIC 18 de noviembre de 2010 Pg. 1 de 17

    E-print Network

    Fernández de Córdoba, Pedro

    Accesibilidad para personas con debilidad motriz Windows 7 ASIC ­ 18 de noviembre de 2010 Pág. 1 de;Accesibilidad para personas con debilidad motriz Windows 7 ASIC ­ 18 de noviembre de 2010 Pág. 2 de 17 Windows 7 ASIC ­ 18 de noviembre de 2010 Pág. 3 de 17 Figura 1-Centro de accesibilidad -Figura 2-Teclado

  15. Accesibilidad para personas con debilidad auditiva ASIC 18 de noviembre de 2010 Pg. 1 de 4

    E-print Network

    Fernández de Córdoba, Pedro

    Accesibilidad para personas con debilidad auditiva Windows XP ASIC ­ 18 de noviembre de 2010 Pág. 1 debilidad auditiva Windows XP ASIC ­ 18 de noviembre de 2010 Pág. 2 de 4 Utilizando el ratón 3 En el cuadro). Utilizando el ratón #12;Accesibilidad para personas con debilidad auditiva Windows XP ASIC ­ 18 de noviembre

  16. Accesibilidad para personas con debilidad visual ASIC 18 de noviembre de 2010 Pg. 1 de 12

    E-print Network

    Fernández de Córdoba, Pedro

    Accesibilidad para personas con debilidad visual Windows 7 ASIC ­ 18 de noviembre de 2010 Pág. 1 de accesibilidad haga Intro sobre la Lupa : #12;Accesibilidad para personas con debilidad visual Windows 7 ASIC Windows 7 ASIC ­ 18 de noviembre de 2010 Pág. 3 de 12 Ctrl+Alt+R Tecla del logotipo de Windows +Esc

  17. 9/26/2014 Recargar el iPhone con aire ser posible? | Informacion Celulares [VC] http://viciodeciudad.com.ar/recargar-el-iphone-con-aire-sera-posible/celulares-informacion/ 1/3

    E-print Network

    Chiao, Jung-Chih

    9/26/2014 ¿Recargar el iPhone con aire será posible? | Informacion Celulares [VC] http://viciodeciudad.com.ar/recargar-el-iphone-con-aire-sera-posible/celulares-informacion/ 1/3 INFORMACIONCELULARES ocupan hoy en día. Hablamos de un nuevo prototipo de sistema de carga para el iPhone, con el que se

  18. ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

    PubMed Central

    Ashkenazy, Haim; Erez, Elana; Martz, Eric; Pupko, Tal; Ben-Tal, Nir

    2010-01-01

    It is informative to detect highly conserved positions in proteins and nucleic acid sequence/structure since they are often indicative of structural and/or functional importance. ConSurf (http://consurf.tau.ac.il) and ConSeq (http://conseq.tau.ac.il) are two well-established web servers for calculating the evolutionary conservation of amino acid positions in proteins using an empirical Bayesian inference, starting from protein structure and sequence, respectively. Here, we present the new version of the ConSurf web server that combines the two independent servers, providing an easier and more intuitive step-by-step interface, while offering the user more flexibility during the process. In addition, the new version of ConSurf calculates the evolutionary rates for nucleic acid sequences. The new version is freely available at: http://consurf.tau.ac.il/. PMID:20478830

  19. Titolo Breve descrizione N. tirocini Titolo studio Conoscenze specifiche Comunicazione con interventi

    E-print Network

    Robbiano, Lorenzo

    progetto "Genova Smart City per i giovani" iniziato nel 2012 con l'obiettivo di diffondere il modello di percorso, collaborando inoltre nei 3 progetti europei Smart Cities and Communities "Transform" - "R2 Cities

  20. Qu sucede con esta imagen? Crculo las diez cosas mal en la

    E-print Network

    limpio #12;¿Qué sucede con esta imagen? -"Servir comida segura" Clave 1. Caliente explotación por debajo lugar en la tabla que no se han eliminado 6. Un alimento no tiene sus propios utensilios de servir en el

  1. Tensión postraumática relacionada con el cáncer–para profesionales de salud (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca de la tensión postraumática y síntomas relacionados en los pacientes con cáncer, sobrevivientes del cáncer y miembros de la familia. Se discuten la evaluación y tratamiento de estos síntomas.

  2. Courses: Economics (ECON) Page 291Sonoma State University 2010-2011 Catalog eCOn 321 lABOr eCOnOMiCS (4)

    E-print Network

    Ravikumar, B.

    history, market structure, labor laws, gender and race, education and training, and collective bargaining, consumers, labor and government. Topics include: constitutional law, administrative law, regulation of monopoly and competition, labor law and international law. Prerequisite: ECON 204 or 205. eCOn 403 Se

  3. Estudio de los NIH señala una relación de la tomografía computarizada (TC) en la infancia con leucemia y con cáncer de cerebro más tarde

    Cancer.gov

    Niños y adultos jóvenes a quienes se les hicieron exploraciones muchas veces con tomografía computarizada (TC), una herramienta de diagnóstico de uso frecuente, tienen un riesgo ligeramente mayor de padecer leucemia y tumores cerebrales en la década posterior a su primera tomografía.

  4. NSF funds iCons and HCC interdisciplinary renewable energy labs The campus' Integrated Concentration in Science (iCons) program and

    E-print Network

    Auerbach, Scott M.

    NSF funds iCons and HCC interdisciplinary renewable energy labs The campus' Integrated Foundation (NSF) funding. These new courses will provide undergraduate students the opportunity will use the NSF award to purchase equipment and develop teaching strategies for their parallel renewable

  5. Range Con: a management evaluation system for assessing sucess of selected range improvement practices 

    E-print Network

    Ekblad, Steven Linn

    1989-01-01

    RANGE CON: A MANAGEMENT EVALUATION SYSTEM FOR ASSESSING SUCCESS OF SELECTED RANGE IMPROVEMENT PRACTICES A Thesis by STEVEN LINN EKBLAD Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment... of the requirements for the degree of MASTER OF SCIENCE August 1989 Major Subject: Range Science RANGE CON: A MANAGEMENT EVALUATION SYSTEM FOR ASSESSING SUCCESS OF SELECTED RANGE IMPROVEMENT PRACTICES A Thesis by STEVEN LINN EEBLAD Approved as to style...

  6. HIPNOSIS APLICADA A NIÑOS QUEMADOS CON DIAGNÓSTICO DE SÍNDROME DE ESTRÉS POST-TRAUMÁTICO 1

    Microsoft Academic Search

    Walter Vargas

    2004-01-01

    El Síndrome de Estrés Post-traumático (S.E.P.T.), diagnosticado en cinco niños quemados fue tratado con la técnica hipnótica, obteniéndose resultados satisfactorios, y de valiosa consideración teórica. Se diseñó un procedimiento a tres pasos, para identificar y abordar con la técnica hipnótica el trauma psíquico: primero, el Escenario Traumático (E.T.); segundo, Inventario de los Elementos del Escenario (I.E.E.); tercero, Dinámica de los

  7. Lupus eritematoso sistemico: un caso di difficile diagnosi differenziale con forme infettive

    Microsoft Academic Search

    L. BIANCHI; S. BALLOTTI; F. G RISOLIA; S. C ASALINI; G. SALVI M. DI MARIA; G. C ALABRI; M. DE MARTINO

    2001-01-01

    purpurica, diffuse a tutto il corpo, compresi palmo delle mani e pianta dei piedi. È presente linfoadenopa- tia laterocervicale bilaterale, con linfoghiandole non dolenti, mobili, di 1-2 cm di diametro. Alla palpa- zione dell'addome si evidenzia epa- tosplenomegalia marcata con en- trambi gli organi debordanti tre dita dall'arcata costale. Gli esami ematici eseguiti all'in- gresso (Tab. I) mostrano aumento della

  8. Breath Biomarkers Networking Sessions at PittCon 2010, Orlando, Florida

    Microsoft Academic Search

    Joachim D Pleil

    2010-01-01

    The Pittsburgh Conference and Exposition, or 'PittCon' (www.pittcon.org\\/), is one of the largest international conferences for analytical chemistry and instrumentation, typically attracting about 25 000 attendees and 1000 commercial exhibitors. PittCon began in 1950 as a small spectroscopy and analytical chemistry gathering and, as the name implies, originated in Pittsburgh, PA. The conference has outgrown its humble beginnings and is

  9. SLUDGE PARTICLE SEPAPATION EFFICIENCIES DURING SETTLER TANK RETRIEVAL INTO SCS-CON-230

    SciTech Connect

    DEARING JI; EPSTEIN M; PLYS MG

    2009-07-16

    The purpose of this document is to release, into the Hanford Document Control System, FA1/0991, Sludge Particle Separation Efficiencies for the Rectangular SCS-CON-230 Container, by M. Epstein and M. G. Plys, Fauske & Associates, LLC, June 2009. The Sludge Treatment Project (STP) will retrieve sludge from the 105-K West Integrated Water Treatment System (IWTS) Settler Tanks and transfer it to container SCS-CON-230 using the Settler Tank Retrieval System (STRS). The sludge will enter the container through two distributors. The container will have a filtration system that is designed to minimize the overflow of sludge fines from the container to the basin. FAI/09-91 was performed to quantify the effect of the STRS on sludge distribution inside of and overflow out of SCS-CON-230. Selected results of the analysis and a system description are discussed. The principal result of the analysis is that the STRS filtration system reduces the overflow of sludge from SCS-CON-230 to the basin by roughly a factor of 10. Some turbidity can be expected in the center bay where the container is located. The exact amount of overflow and subsequent turbidity is dependent on the density of the sludge (which will vary with location in the Settler Tanks) and the thermal gradient between the SCS-CON-230 and the basin. Attachment A presents the full analytical results. These results are applicable specifically to SCS-CON-230 and the STRS filtration system's expected operating duty cycles.

  10. Evaluation of the ACT*DE*CON{sup SM} process for treating gunite tank sludge

    SciTech Connect

    Spencer, B.B.; Chase, C.W.; Egan, B.Z.

    1996-05-01

    A test was conducted to evaluate this process for selectively removing actinides from Gunite tank sludge. Mixed waste sludge from Gunite tank W-6 was subjected to the ACT*DE*CON selective leaching process. (Nearly all the TRU content was attributed to Pu.) The sludge sample was first washed with 0.01M NaOH to remove excess sodium and nitrate in the interstitial liquid supernatant. The washed wet solids were treated with the ACT*DE*CON solvent (aqueous carbonate solution containing a chelating agent and an oxidant), using a ratio of 20 ml solvent per gram wet solids. Sludge and solvent were separated by centrifugation, and the ACT*DE*CON treatment was repeated twice. Analyses showed that 71% of the solids in the sludge were dissolved while 80% of the TRU-waste components dissolved. Low separation of the TRU-waste components from other components of the sludge mixture is indicated. Almost all the U and Ca were removed from the sludge. For sludges where most of the TRU content is Pu, the ACT*DE*CON process as tested is not effective in rendering the sludge a non-TRU waste. It is recommended that ACT*DE*CON be optimized for this specific application and that other processes using different chelating and oxidizing agents be tested. Also, the ACT*DE*CON process should be tested on TRU mixed waste in which most of the TRU elements are not Pu.

  11. Prevalencia y tamizaje del Trastorno por Déficit de Atención con Hiperactividad en Costa Rica

    PubMed Central

    Weiss, Nicholas T.; Schuler, Jovita; Monge, Silvia; McGough, James J.; Chavira, Denise; Bagnarello, Monica; Herrera, Luis Diego; Mathews, Carol A.

    2015-01-01

    Resumen La investigación tuvo como propósito estimar la prevalencia del Trastorno por Déficit de Atención con Hiperactividad (TDAH) en Costa Rica y determinar si la versión en español del cuestionario Swanson Nolan and Pelham Scale IV (SNAP-IV) es un instrumento de tamizaje útil en una población de niños y niñas escolares costarricenses. El instrumento fue entregado a padres y maestros de 425 niños entre 5 y 13 años de edad (promedio = 8.8). Todos fueron evaluados con el instrumento Swanson, Kotkin, Agler, M-Flynn and Pelham Scale (SKAMP). Su diagnóstico fue confirmado con una entrevista clínica. La sensibilidad y la especificidad del SNAP-IV fueron evaluadas como predictores de criterios de diagnóstico según el DSM-IV. La prevalencia puntual en la muestra del TDAH fue del 5%. El tamizaje más preciso lo hizo el SNAP-IV completado por el maestro en un corte de 20%, con una sensibilidad de 96% y una especificidad de un 82%. La sensibilidad de los instrumentos completados por los padres fue más baja que aquella de los maestros. El SNAP-IV completado por las maestras con un corte aislando el 20% de los mayores puntajes categorizó correctamente a un 87% de los sujetos. PMID:22432094

  12. L'altro, invece, fu importante per i contatti con l'elite culturale giapponese, nella fattispecie per gli articoli sul ??? ??? ??? ???-Bushido , ed i suoi rapporti con il

    Microsoft Academic Search

    Inazo Nitobe; Phra Mongkut

    ???????????????????????????????????? , ritenuto l'antesignano della modernizzazione del paese, il quale intraprese la via di un avvicinamento con l'Occidente al fine di preservarne l'indipendenza politica, culturale e spirituale. A tale scopo egli impose una modifica dello stile di vita, negli abiti, nell'architettura, favorendo lo studio della lingua inglese e l'acquisizione della tecnologia occidentale. Da parte nostra, prendendo spunto da questi studi

  13. Presencia de movimientos chiítas en América Latina: Su relación con los atentados de Buenos Aires (1992, 1994) y con el eje Caracas-Teherán

    Microsoft Academic Search

    Isaac Caro

    2011-01-01

    Resumen:Este trabajo tiene por objetivo examinar la presencia de movimientos chiítas radicales en América Latina, algunos de ellos comprometidos en acciones violentas, especialmente en dos zonas geográficas. Primero, en la denominada triple frontera de Argentina, Paraguay y Brasil, presencia vinculada con los atentados contra la embajada de Israel en 1992 y contra la Asociación Mutual Israelita Argentina en 1994, ambos

  14. Soluciones analiticas AL problema de jets con velocidad de eyeccion variable EN EL tiempo.

    NASA Astrophysics Data System (ADS)

    Canto, J.; Raga, A. C.; D'Alessio, P.

    1998-11-01

    Se presenta un nuevo metodo que permite resolver de manera exacta y analitica las ecuaciones que describen un jet hipersonico con velocidad de eyeccion variable en el tiempo. El metodo se basa en consideraciones sencillas de conservacion de momento para las superficies de trabajo que se forman en el interior del jet. Como ejemplo, se presentan soluciones para jets con variacion sinusoidal en la velocidad de eyeccion, y tambien para el caso de un incremento lineal en el tiempo. Estas soluciones analiticas tienen una clara aplicacion en la interpretacion de las observaciones de jets asociados a objetos Herbig-Haro.

  15. GeConT 2: gene context analysis for orthologous proteins, conserved domains and metabolic pathways

    PubMed Central

    Martinez-Guerrero, C. E.; Ciria, R.; Abreu-Goodger, C.; Moreno-Hagelsieb, G.; Merino, E.

    2008-01-01

    The Gene Context Tool (GeConT) allows users to visualize the genomic context of a gene or a group of genes and their orthologous relationships within fully sequenced bacterial genomes. The new version of the server incorporates information from the COG, Pfam and KEGG databases, allowing users to have an integrated graphical representation of the function of genes at multiple levels, their phylogenetic distribution and their genomic context. The sequence of any of the genes can be easily retrieved, as well as the 5? or 3? regulatory regions, greatly facilitating further types of analysis. GeConT 2 is available at: http://bioinfo.ibt.unam.mx/gecont. PMID:18511460

  16. Science for conServation 293 Loss of genetic diversity and

    E-print Network

    Jamieson, Ian

    bird species #12;Loss of genetic diversity and inbreeding in New Zealand's threatened bird species Ian. 59 p. Loss of genetic diversity and inbreeding in New Zealand's threatened bird species Ian GScience for conServation 293 Loss of genetic diversity and inbreeding in New Zealand's threatened

  17. Onion Routing Access Con gurations Paul F. Syverson, Michael G. Reed, and David M. Goldschlag

    E-print Network

    Onion Routing Access Con gurations Paul F. Syverson, Michael G. Reed, and David M. Goldschlag Naval Research Laboratory Abstract Onion Routing is an infrastructure for private com- munication over and tra c analysis. Thus it hides not only the data being sent, but who is talking to whom. Onion Routing

  18. BANDO PER IL RECLUTAMENTO DI UN RICERCATORE CON RAPPORTO DI LAVORO A TEMPO DETERMINATO TIPOLOGIA A

    E-print Network

    Guidoni, Leonardo

    A Bando RTD n. 02/2014 Il Direttore del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer Fisiologia e Farmacologia "Vittorio Erspamer" di n. 1 posto di ricercatore con rapporto di lavoro a tempo economica della quota di competenza a carico del Dipartimento di Fisiologia e Farmacologia "Vittorio

  19. Studies of Global Stability of Field-Reversed Con guration Plasmas Using A Rigid Body Model

    E-print Network

    Studies of Global Stability of Field-Reversed Con guration Plasmas Using A Rigid Body Model H. Ji guration FRC plasmas has been stud- ied using a simple rigid body model in the parameter space of s ratio equation of motion for each global mode is formulated and analyzed using a rigid body model of the FRC

  20. In my last column I explained why I think full-fledged business-to-con-

    E-print Network

    In my last column I explained why I think full-fledged business-to-con- sumer e-commerce (B2C is currently the more difficult of the two. The reasons are twofold. One, B2C e-commerce product specifications computations for managing the manufacturing and logistics neces- sary to efficiently satisfy B2C requirements

  1. El estudio NCI-MATCH vinculará medicamentos dirigidos para el cáncer con anomalías genéticas

    Cancer.gov

    Los investigadores del estudio a nivel nacional NCI-MATCH: Análisis molecular para la elección de tratamientos, anunciaron que el estudio busca determinar la eficacia de los tratamientos dirigidos en personas con tumores que presentan mutaciones genéticas específicas independientemente de su tipo de cáncer.

  2. INVESTIGATION OF THE PHYSICAL CONDITIONS CON-TROLLING SPAWNING OF OYSTERS AND THE OCCUR-

    E-print Network

    was to study the effect of the physical conditions on the oyster and oyster larvre in this typical location. These studies were conducted under the direction of Dr. Paul S. Galtsoff, in charge of oyster investigationsINVESTIGATION OF THE PHYSICAL CONDITIONS CON- TROLLING SPAWNING OF OYSTERS AND THE OCCUR- RENCE

  3. Maximum Stable Throughput of FS-ALOHA under Delay Con-B. Van Houdt

    E-print Network

    Maximum Stable Throughput of FS-ALOHA under Delay Con- straints B. Van Houdt and C. Blondia. This paper studies the maximum stable throughput of FS-ALOHA, a random access algorithm for dynamic bandwidth factor in the QoS provisioning. Although Slotted ALOHA is easy to implement in such an environment

  4. CONTRIBUTI ALL'ATTIVITÀ PRENORMATIVA NEL CAMPO DEL CONSOLIDAMENTO STRUTTURALE CON MATERIALI COMPOSITI FIBRORINFORZATI

    Microsoft Academic Search

    L. Ascione; L. Feo

    Sommario La presente memoria contribuisce a diffondere i risultati dell'attività prenormativa spontanea svolta da alcuni docenti dei settori della Scienza e della Tecnica delle Costruzioni nel campo del consolidamento strutturale con materiali compositi fibrorinforzati (FRP). Tale attività ha portato alla redazione del documento tecnico CNR-DT 200\\/2004 dal titolo: \\

  5. HÁBITOS DE ESTUDIO, ACTITUDES Y AUTOESTIMA RELACIONADOS CON RENDIMIENTO ACADÉMICO EN ESTUDIANTES DE ENFERMERÍA

    Microsoft Academic Search

    Fabiola Cruz Núñez

    2010-01-01

    Determinar la relación que existe entre hábitos de estudio, actitudes y autoestima con el rendimiento académico de los estudiantes de la Facultad de Enfermería de la Universidad Veracruzana. METODOLOGÍA: Diseño de investigación descriptivo, correlacional. La población estuvo constituida por 377 estudiantes inscritos durante el periodo Febrero – Julio, 2010. El tipo de muestreo fue probabilístico estratificado; la muestra fue de

  6. |September 2004| SPIE's oemagazine |25 enses are key elements of optical systems. Most con-

    E-print Network

    Wu, Shin-Tson

    |September 2004| SPIE's oemagazine |25 L enses are key elements of optical systems. Most con- ventional lenses are made of glass, polymer, or other transparent solid materials. These lenses have fixed focus. To tune the focal length continuously, optical design- ers have developed the zoom lens, which

  7. Comparación entre un arrancador electrónico diseñado con IGBT's y un arrancador electrónico comercial

    Microsoft Academic Search

    M. C. Gabriel; Domínguez Sánchez; Mario Salvador; Esparza González

    Resumen. En este artículo se presenta una comparación entre un arrancador electrónico de estado sólido diseñado para motores trifásicos en el Instituto Tecnológico de A guascalientes basado en IGBT's (Transistores Aislados por Compuerta) con una propuesta de disparo, se presenta el diseño del arrancador, los resultados obte nidos y la respuesta para las mismas condiciones de opera ción de un

  8. Capacidad reproductiva de Pinus nigra subsp. salzmannii en relacin con la edad de la planta madre

    E-print Network

    Herrera, Carlos M.

    Capacidad reproductiva de Pinus nigra subsp. salzmannii en relación con la edad de la planta madre fertilidad del pino salgareño (Pinus nigra subsp. salzmannii) conforme los árboles envejecen. La fertilidad bosques de montaña del sur de Europa. Palabras clave: Pinus nigra, fertilidad, senescencia de las plantas

  9. DIGITAL.CSIC: "Catalogacin con Dublin Core, gestin de derechos de

    E-print Network

    DIGITAL.CSIC: "Catalogación con Dublin Core, gestión de derechos de autor y permisos de editores;Copyright y el acceso abierto #12;¿De qué estamos hablando? · Derechos de autor: conjunto de normas y principios que regulan los derechos morales y patrimoniales que la ley concede a los autores por el solo

  10. Mul$-scale Demand-Side Management for Con$nuous Power-intensive Processes

    E-print Network

    Grossmann, Ignacio E.

    and uncertainty in prices · Timing and produc(on quan((es (DR)* · Inventory management inventory facilitate performing Demand-side Management (DSM) at air separa$on plants1 Mul$-scale Demand-Side Management for Con$nuous Power-intensive Processes

  11. Both methods made the cells sensitive to drug-induced apoptosis (Fig. 1b, c). Con-

    E-print Network

    Chapman, Clark R.

    Both methods made the cells sensitive to drug-induced apoptosis (Fig. 1b, c). Con- versely a partial reversion to normal glandular structures, which then were resistant to apoptosis (Fig. 1a, b with abnormal anchorage to the basement membrane did not protect against apoptosis. Interestingly, however

  12. PROCESSING IN THE ENCRYPTED DOMAIN USING A COMPOSITE SIGNAL REPRESENTATION: PROS AND CONS

    E-print Network

    PROCESSING IN THE ENCRYPTED DOMAIN USING A COMPOSITE SIGNAL REPRESENTATION: PROS AND CONS Tiziano proposed that allows to speed up linear operations on encrypted signals via parallel processing and to reduce the size of the encrypted signals. Though many of the most common sig- nal processing operations

  13. Iron formations are typically thinly bed-ded or laminated sedimentary rocks con-

    E-print Network

    Fischer, Woodward

    222 ABSTRACT Iron formations are typically thinly bed- ded or laminated sedimentary rocks con- taining 15% or more of iron and a large pro- portion of silica (commonly >40%). In the ca. 2590­2460 Ma Campbellrand-Kuruman Complex, Transvaal Supergroup, South Africa, iron formation occurs as a sediment- starved

  14. El Reto de Vincular a los Pequeños Productores de Papa con la Agroindustria

    Microsoft Academic Search

    Thomas Bernet; Martín Lara; Pedro Urday; André Devaux

    Resumen El aumento del consumo de papa procesada está permitiendo que la agricultura por contrato gane importancia. Los pequeños productores de papa podrían aprovechar esta modalidad para superar sus dificultades en la comercialización, accediendo a un mercado seguro con precios rentables y estables. No obstante, la literatura revisada y un caso específico de la Sierra Central del Perú demuestran que

  15. Matemtica para ubicarse En cualquier lugar del planeta y ms all con el GPS

    E-print Network

    Groisman, Pablo

    Matemática para ubicarse En cualquier lugar del planeta y más allá con el GPS matbaires 09 Pablo Groisman Dpto. de Matemática FCEN-UBA CONICET #12; ¿Qué es GPS? #12; Aplicaciones #12 corrección de errores para los GPS. Reloj atómico que marca la hora oficial de EEUU. (In) presición: 1

  16. HEP/123-qed Precessing Domains and Castaing Instability in Conned Alkali

    E-print Network

    Meyerovich, Alex

    HEP/123-qed Precessing Domains and Castaing Instability in ConÞned Alkali Gases A. Kuklov textdate; Published textdate) Abstract We explore analogy between two-component quantum alkali gases of these effects for alkali gases and make suggestions for new types of experiments including the observation

  17. Aplicacin del paradigma CellDEVS binario con tiempo para modelado y simulacin de sistemas

    E-print Network

    Wainer, Gabriel

    Aplicación del paradigma Cell­DEVS binario con tiempo para modelado y simulación de sistemas verificación de los modelos. De esta forma se puede lograr el desarrollo eficiente y reducido en costo de soluciones de simulación para estos sistemas. Keywords: Simulación a Eventos Discretos, Modelado, espacios de

  18. ^O l ll ORNL/CON-125 Design Options to Test the

    E-print Network

    Oak Ridge National Laboratory

    ^O l ll ORNL/CON- 125 A 5 A Design Options to Test the Effects of Financial CARBIDE Incentives THE EFFECTS OF FINANCIAL INCENTIVES IN A UTILITY CONSERVATION PROGRAM: TVA'S HEAT PUMP WATER HEATER PROGRAM Comparisons ............... 25 2.3.2 One Way Layout Design .............. 26 3. DISTRIBUTOR LEVEL ASSIGNMENT

  19. The Value of Literacy Beyond Reading: Empowering Adult Women Through Knowledge and Con...dence

    E-print Network

    Bandyopadhyay, Antar

    The Value of Literacy Beyond Reading: Empowering Adult Women Through Knowledge and Con funded by the Social Science Research Council of Canada. 1 #12;Abstract Adult female literacy around the world to institute large scale adult literacy programs. However, evidence on the e

  20. On the Detection of Con icts in Diagnostic Bayesian Networks Using Abstraction

    E-print Network

    Valtorta, Marco

    On the Detection of Con icts in Diagnostic Bayesian Networks Using Abstraction Young-Gyun Kim Bayesian net- work (the base model) and constructs, with- out assistance, a bipartite network to be used and imple- mented. 1 INTRODUCTION Developing a diagnostic expert system that uses a Bayesian network

  1. MODELO LINGSTICO DE TOMA DE DECISIONES MULTICRITERIO CON EXPRESIONES LINGSTICAS COMPARATIVAS

    E-print Network

    Granada, Universidad de

    #12;#12;#12;#12;#12;#12;MODELO LINGÜÍSTICO DE TOMA DE DECISIONES MULTICRITERIO CON EXPRESIONES. Posteriormente, presentamos un mode- lo lingüístico de toma de decisiones multicriterio que utiliza dichas lingüísticas comparativas, conjunto de términos lingüísticos difusos dudosos, toma de decisiones multicriterio

  2. LIXIVIACIÓN DE MENAS AURÍFERAS CON SALES OXIDANTES EN MEDIO ÁCIDO MEDIANTE EL PROCESO SEVERO

    Microsoft Academic Search

    Palacios C. Severo

    El trabajo de Lixiviación se desarrolla en Menas, Concentrados y Material Refractario (sulfurado), en pulpa o partículas (agitación o pilas) a temperatura ambiente con tiempo de lixiviación máximo de doce horas, usando como medio lixiviante el ácido sulfúrico concentrado adicionado sales oxidantes como los cloruros y nitrato de sodio o nitrato de amonio en distintas proporciones. Los resultados obtenidos respecto

  3. Sobre Como Varian las Firmas Manuscritas con el Tiempo: una Modelizacion Sigma Lognormal

    E-print Network

    Autonoma de Madrid, Universidad

    de edad basado en los par´ametros del modelo. 1 Introducci´on Como en cualquier nuevo ´area de- conocimiento, con el objetivo de conseguir menores tasas de error. Como conse- cuencia, se han pasado por alto nueva aproximaci´on para el estudio de firmas pertenecientes a grupos de edades dis- tintas. #12;La

  4. ¿POR QUE COMENZAR CON UN INGRESO CIUDADANO PARA LOS MENORES EN AMERICA LATINA?

    Microsoft Academic Search

    Alberto C. Barbeito; Rubén M. Lo Vuolo

    La característica central de todas las nociones afines con el concepto de ingreso básico o ingreso ciudadano (IC) es que se refieren a un arreglo institucional que garantiza cierta forma de ingreso incondicional a las personas, esto es, un ingreso para cuyo acceso no se requiere ninguna otra condición personal que la de ser ciudadano. Por ejemplo, no se requiere

  5. IMPLICACIONES DEL MODELO DE ENSEÑANZA NATURAL DEL LENGUAJE EN LA INTERVENCION DE PERSONAS CON AUTISMO

    Microsoft Academic Search

    Pedro Gortázar

    Equipo CEPRI RESUMEN: El Modelo de Tratamiento Natural del Lenguaje constituye el para- digma de intervención actualmente más válido para hacer frente a los déficits sociales y comunicativos de las personas con autismo. En esta ponencia se discuten las implicaciones de este Modelo de cara a la formu- lación de objetivos curriculares, definición de criterios de respuesta, técnicas de entre-

  6. iCon: Utilizing Everyday Objects as Additional, Auxiliary and Instant Tabletop Controllers

    E-print Network

    Ouhyoung, Ming

    circumstances, low engagement with selected objects, and medium-to-high frequency of use. The proposed apiCon: Utilizing Everyday Objects as Additional, Auxiliary and Instant Tabletop Controllers Kai of users as additional, auxiliary, and instant tabletop controllers. Based on this approach, a prototype

  7. RESUMEN: El abandono de las formas indgenas y tradicionales de relacionarse con

    E-print Network

    Paris-Sud XI, Université de

    a V E : Tecnologías indígenas, arqueología, desarrollo sostenible, agricultura, pastoreo, silvicultura modelos de desarrollo que responden a exigencias foráneas. Los estudios sociales han integrado el concepto de desarrollo en sus análisis con diferentes enfoques y aplicaciones, pese a que persiste la

  8. Bayesian-network Con rmation of Software Testing Uncertainties Debra J. Richardson

    E-print Network

    Ziv, Hadar

    networks to con rm beliefs in the validity of software artifacts and relations in an elevator control, such as described for the Therac-25 medical radiation device LT93 or else reported, for example, in the comp unexplored with notable exception of software reliability models Lit79 and validation of software

  9. I JORNADAS SOBRE TRASTORNO DE DFICIT DE ATENCIN CON/SIN HIPERACTIVIDAD. CONOCIENDO EL

    E-print Network

    Rey Juan Carlos, Universidad

    I JORNADAS SOBRE TRASTORNO DE DÉFICIT DE ATENCIÓN CON/SIN HIPERACTIVIDAD. CONOCIENDO EL TDAH PARA SU CORRECTA INTERVENCIÓN EN EL AULA Si existe un trastorno infantil que desborda la atención de los profesores y que afecta al desarrollo normal de cualquier aula de clase es el Trastorno por Déficit de

  10. Derivaciones perezosas en Programaci'on L'ogica con restricciones ecuacionales*

    E-print Network

    Alpuente, María

    bajo una teor'ia de la igualdad presentada como una teor'ia ecuacional de Horn E [1* *, 2]. CLP sobre la estructura X con la que se parametriza el esquema. El concepto de estructura especifica el.e. la partici'on m'as fina inducida por una teor'ia de la igualdad E sobre el* * Universo de Herbrand H

  11. DESign AnD conStruction College of Engineering and Mines

    E-print Network

    Hartman, Chris

    DESign AnD conStruction MAnAgEMEnt College of Engineering and Mines Department of Civil for Certificate: 15 credits The graduate certificate in design and construction management is de- signed in the construction industry. The program was designed in collaboration with construction industry em- ployers

  12. ConAir: Featherweight Concurrency Bug Recovery Via Single-Threaded Idempotent Execution

    E-print Network

    Lu, Shan

    ConAir: Featherweight Concurrency Bug Recovery Via Single-Threaded Idempotent Execution Wei Zhang1 of Wisconsin­Madison 2Google, Inc {wzh,dekruijf,ali28,shanlu,karu}@cs.wisc.edu Abstract Many concurrency bugs that help software survive hidden concurrency bugs during production runs. To help developers, we need

  13. State based protocols are protocols in which the handling of one message depends on the con-

    E-print Network

    Dean, Thomas R.

    on the con- tents of previous messages. Testing such proto- cols, for security or for other purposes usually to evalu- ate the security of an implementation. One ap- proach that can be adapted is Syntax Testing [2 messages to test the security of a given applica- tion. However before sending multiple mutated versions

  14. PARA ACABAR CON LA VERDAD-DEMOSTRACION. BACHE,LARD, CANGUILHEM, FOUCAULT

    E-print Network

    Paris-Sud XI, Université de

    and the scope of Michel Foucault's uhistory of truthr, i.e. his history of the relationship between truth, power gouuernement des uiuants, 30.01.80) Uno de los principales objetivos de la reflexión del último Michel FoucaultPARA ACABAR CON LA VERDAD-DEMOSTRACION. BACHE,LARD, CANGUILHEM, FOUCAULT Y LA HISTOzuA DE, LOS (RE

  15. Razonamiento automtico en programacin genrica con ACL2: estudio de un caso

    E-print Network

    Alonso, José A.

    Razonamiento automático en programación genérica con ACL2: estudio de un caso I. Medina BuloÝ , J estudio de un caso de razonamiento formal sobre programas genéricos en ACL2. En él aparecen (entre otras genéricos, ACL2 Resumen En este artículo se estudia un caso de formalización y demostración automática en

  16. ConText: An algorithm for determining negation, experiencer, and temporal status from clinical reports

    Microsoft Academic Search

    Henk Harkema; John N. Dowling; Tyler Thornblade; Wendy Webber Chapman

    2009-01-01

    In this paper we describe an algorithm called ConText for determining whether clinical conditions mentioned in clinical reports are negated, hypothetical, historical, or experienced by someone other than the patient. The algorithm infers the status of a condition with regard to these properties from simple lexical clues occurring in the context of the condition. The discussion and evaluation of the

  17. which settles the debate about the exclusiveness of memory con-solidation during sleep.

    E-print Network

    which settles the debate about the exclusiveness of memory con- solidation during sleep. In describing the findings regarding procedural memory and sleep in humans, Walker states that the evidence & Born 1999a]) as well as different manipulation techniques (e.g., early versus late sleep [Plihal & Born

  18. he quantum behavior change paradigm con-siders the possibility that health behavior

    E-print Network

    Plaut, David C.

    constraint satisfaction artificial neural network) and tested whether the model exhibited quantum404 T he quantum behavior change paradigm con- siders the possibility that health behavior may a novel analysis of the quantum behavior change para- digm that generated several implications for health

  19. ESPACIOS DE TRABAJO DE KNOWCAT Los usuarios pueden trabajar con el sistema en los siguientes espacios

    E-print Network

    Cobos, Ruth

    APÉNDICE A ESPACIOS DE TRABAJO DE KNOWCAT Los usuarios pueden trabajar con el sistema en los siguientes espacios: 1. Espacio de Conocimiento: espacio que permite a los usuarios trabajar en la gestión del conocimiento del grupo. 2. Espacio de Comunidad de Usuarios: espacio que proporciona a los

  20. INSTRUMENTOS PARA EL DESARROLLO Y LA DINAMIZACIN DE CIUDADES Y ESPACIOS CON

    E-print Network

    Escolano, Francisco

    INSTRUMENTOS PARA EL DESARROLLO Y LA DINAMIZACIÓN DE CIUDADES Y ESPACIOS CON PATRIMONIO HISTÓRICO aplicación incluya todos los espacios naturales, las áreas urbanas, periurbanas y rurales así como el litoral interesantes beneficios económicos y socio-laborales a los espacios que se desarrollen en su sector, deben

  1. denomino CASA CON-CIENCIA. Este proyecto naci gracias a la inquietud de la Asociacin Gilberto

    E-print Network

    , generando una mayor Con-Ciencia y responsabilidad social. Así esta vivienda de 80 metros cuadrados de vivienda que ofreciera un espacio digno, durable y sustentable en la eficiencia de los recursos naturales sus 8 hijos cambió radicalmente. El proyecto de vivienda semilla nace de un convenio tripartita

  2. Yang-Baxter Invariants for Line Con gurations Department of Mathematics and Computer Science

    E-print Network

    Penne, Rudi

    , the diagrams of isotopic line con#12;gurations can be connected by means of diagram moves #18;a la Reidemeister matrix with respect to a #12;xed basis. Let dim(V ) = n. A labeling of a line diagram is a choice out the opportunity to use two matrices, (#26; ab cd ) and (#26; ab cd ). For each diagram labeling we can multiply

  3. ELEMENTOS TEÓRICOS PARA LA CONSTRUCCIÓN DE INDICADORES DE GÉNERO RELACIONADO CON PROYECTOS

    Microsoft Academic Search

    Raiza Trapote Fernández; Iris María González Torres; María Isabel Castillo Ramos

    2012-01-01

    En la presente investigación se conceptualizan las políticas públicas esbozando la correspondencia de los proyectos como manifestación de dichas políticas; con la utilización del método análisis-síntesis. Seguidamente se abordan los proyectos de desarrollo y el enfoque de género destacando su importancia desde la concepción del proyecto. Finalmente se proponen los elementos que en el orden teórico sustentan la construcción de

  4. pag. 1S. Marsili-Libelli: Introduzione ai Fuzzy Sets Ragionamento approssimato con

    E-print Network

    pag. 1S. Marsili-Libelli: Introduzione ai Fuzzy Sets Ragionamento approssimato con concetti definiti in modo vago #12;pag. 2S. Marsili-Libelli: Introduzione ai fuzzy sets E' più importante la precisione o il significato? #12;pag. 3S. Marsili-Libelli: Introduzione ai fuzzy sets Valori Crisp e Fuzzy

  5. Red GPS a Tiempo Real con Precisiones Centrimtricas para Utilizar en los Sistemas de

    E-print Network

    Gilbes, Fernando

    Red GPS a Tiempo Real con Precisiones Centrimétricas para Utilizar en los Sistemas de Información · GPS Reference Stations RED CORS del NGS en PR Magueyes CORS Site-PRMI #12;Concepto Desarrollo Tecnológico Instrumentación · GPS Internet Ready Red de GPS a tiempo Real en proceso Leica Spider Net en

  6. MlBibTEX meets ConTEXt JEAN-MICHEL HUFFLEN

    E-print Network

    Paris-Sud XI, Université de

    of both ConTEXt and MlBibTEX features when they are used together. Also, many end-users are accustomed, bibliographies, bibliography styles, BibTEX, MlBibTEX. Introduction Listing the bibliographical references cited, searches bibliog- raphy database files for resources associated with these keys, and arranges them

  7. Problemi degli investimenti in venture capital con particolare riferimento al settore delle biotecnologie

    Microsoft Academic Search

    Virginia DAgostino

    2006-01-01

    Problemi degli investimenti in venture capital con particolare riferimento al settore delle biotecnologie (di V. Dagostino) - ABSTRACT: Il presente articolo si propone di esaminare le modalità di selezione e gestione di progetti finanziati da parte delle società di Venture Capital (VC) e di Private Equity. L’obiettivo del lavoro è, tra l’altro, quello di verificare se tra fondi italiani e

  8. Modi istantanei di vibrazione radiale ed elicoidale: teoria a confronto con

    E-print Network

    Cocco, Simona

    Capitolo 4 Modi istantanei di vibrazione radiale ed elicoidale: teoria a confronto con gli a temperatura ambiente. In una molecola di DNA i modi di vibrazione delle coppie di basi nel legame idrogeno e della doppia elica sono modi collettivi , essi coinvolgono cio#18;e gruppi di atomi ed avvengono su una

  9. EDUCATOR'S GUIDE Field Trip to the Moon Educator Guide COnTEnTS

    E-print Network

    into Earth's orbit· Earth's Magnetosphere· Spacecraft Flyby· Moon (approach, orbit, and landing)· ClassroomEDUCATOR'S GUIDE #12;Field Trip to the Moon Educator Guide COnTEnTS Table of Contents 3 Program 55 Medical 70 Name Tags #12;Field Trip to the Moon Educator Guide OVERVIEW What Is Field Trip

  10. Retroperitoneal ancient schwannoma: case report and analysis of clinico-radiological findings

    Microsoft Academic Search

    M Giglio; V Giasotto; M Medica; F Germinale; F Durand; G Queirolo; G Carmignani

    2002-01-01

    Ancient schwannoma is a rare subtype of typical schwannoma, with histological predominance of degenerative findings. We report the second case of retroperitoneal ancient schwannoma (occurred in a 45-year-old female referred to our institution for an unremitting right lumbar pain) and pinpoint clinical, radiological, prognosis and therapeutic aspects of this tumor.

  11. Clinico-epidemiological study of human fascioliasis in an endemic focus in Dakahlia Governorate, Egypt.

    PubMed

    el-Shazly, A M; Soliman, M; Gabr, A; Haseeb, A N; Morsy, A T; Arafa, M A; Morsy, T A

    2001-12-01

    Human fascioliasis is increasing in the Nile Delta particularly in Dakahlia Governorate, where it reached 7.47%. In this study, the tetrad of fascioliasis was established as high eosinophilia (100%), fever (85.6%), painful hepatomegaly (81.93%) and anaemia (100%). The laboratory results showed ESR accelerated in 87%, ALT elevated in 21.5%, AST elevated in 21.9%, S. bilirubin elevated in 16.5%, gamma GT elevated in 80.6%, and SAP elevated in 76.4%. Abdominal ultrasonography showed variable findings, as hepatomegaly, splenomegaly, periportal fibrosis, thickened wall of gall bladder, dilated common bile duct, dilated biliary radicals (partial), dilated common bile duct and biliary radicals (total), Fasciola worms in gall bladder, Fasciola worms in common bile duct, stones in gall bladder, stones in bile duct, cystic lesions in the liver, local lesions in the liver and ascitis. The highest was hepatomegaly in 81.93% of fascioliasis patients and the lowest was biliary dilated radicles (partial) in 0.26%. PMID:11775099

  12. White matter in temporal lobe epilepsy: clinico-pathological correlates of water diffusion abnormalities

    PubMed Central

    Rodríguez-Cruces, Raúl

    2015-01-01

    Using magnetic resonance imaging, it is possible to measure the behavior of diffusing water molecules, and the metrics derived can be used as indirect markers of tissue micro-architectural properties. Numerous reports have demonstrated that patients with temporal lobe epilepsy (TLE) have water diffusion abnormalities in several white matter structures located within and beyond the epileptogenic temporal lobe, showing that TLE is not a focal disorder, but rather a brain network disease. Differences in severity and spatial extent between patients with or without mesial temporal sclerosis (MTS), as well as differences related to hemispheric seizure onset, are suggestive of different pathophysiological mechanisms behind different forms of TLE, which in turn result in specific cognitive disabilities. The biological interpretation of diffusion abnormalities is based on a wealth of information from animal models of white matter damage, and is supported by recent reports that directly correlate diffusion metrics with histological characteristics of surgical specimens of TLE patients. Thus, there is now more evidence showing that the increased mean diffusivity (MD) and concomitant reductions of diffusion anisotropy that are frequently observed in several white matter bundles in TLE patients reflect reduced axonal density (increased extra-axonal space) due to smaller-caliber axons, and abnormalities in the myelin sheaths of the remaining axons. Whether these histological and diffusion features are a predisposing factor for epilepsy or secondary to seizures is still uncertain; some reports suggest the latter. This article summarizes recent findings in this field and provides a synopsis of the histological features seen most frequently in post-surgical specimens of TLE patients in an effort to aid the interpretation of white matter diffusion abnormalities. PMID:25853084

  13. Oncoplastic breast surgery: initial experience at the Centro Clinico de Estereotaxia—CECLINES, Caracas, Venezuela

    PubMed Central

    Acosta-Marin, V; Acosta-Freites, V; Contreras, A; Ravelo, R; Fuenmayor, G; Marin, C; Ramirez, A; Acosta-Marin, M; Perez-Fuentes, J; Longobardi, I; Esteves, H

    2014-01-01

    Background Breast-conserving surgery (BCS) may sometimes lead to deformities in the remaining breast. Oncoplastic surgery (OPS) aims to improve our aesthetic results even in the case of major volume resections. The purpose of this study is to provide an objective evaluation of our initial experience with OPS, mainly based on the levels of satisfaction reported by both patients and surgeons. Patients and Methods This prospective study was performed at CECLINES in Caracas, Venezuela, between January 2011 and October 2012. It involved 107 consecutive patients in two groups: 52 patients with level II OPS versus 55 patients with ‘standard’ BCS (SBCS). We evaluated the level of satisfaction and cosmetic outcome at 6 and 12 months post-operation using a score from 1 (bad) to 5 (excellent). The cosmetic score was recorded during the follow-up by the surgeon, by phone calls, and photographs were reviewed by a panel of four observers. Results The participation rate in the cosmetic outcome/level of satisfaction evaluation was 100% at 6 months and 96.2% at 12 months. The average tumour size was 23 mm [standard deviation (SD): 13.5] for the OPS group versus 17.6 mm (SD: 8.3) for the SBCS group (p = 0.017). The average weight for the surgical specimen was 101 g (range: 30–512 g) in the OPS group versus 60.4 g (range: 20–135 g) in the SBCS group (p = 0.004). The OPS techniques most performed were round block 40.3% (21/52), inverted T mammoplasty 26.8% (14/52) and vertical scar mammoplasty 15.3% (8/52). Of all the patients, 51.9% (27/52) had symmetrisation procedures performed distributed according to the period of the study: 77.2% (17/22) in 2011, 56.6% (17/30) in 2012, and 18.1% (6/33) in 2013. The rate of complications was 5.7% (3/52) in the OPS group and 0% for the SBCS group (p < 0.005). The average cosmetic score at 6 months by patients in the OPS group was 4.4; patient satisfaction scores of 4 (good) and 5 (excellent) were 88.4%. In the SBCS group at 6 months, the mean score reported by patients was 4.2, with scores 4–5 being 83.4% (p = 0.644). The cosmetic score by surgeons in the OPS group at 6 months was 4.5; the surgeon satisfaction scores of 4–5 were 94.2%. In the SBCS group, the surgeons’ mean score at 6 months was 4.1, with 84.5% of scores being 4 or 5 (p < 0.005). The final cosmetic score by patients in the OPS group at 12 months was 4.5; patient satisfaction scores of 4–5 were 90.4%. In the SBCS group, the final mean score at 12 months by patients was 4.2, with 77.5% of scores being 4 or 5 (p < 0.005). The final cosmetic score by surgeons in the OPS group at 12 months was 4.5; surgeon satisfaction scores of 4–5 were 92.3%. In the SBCS group, the surgeons’ final mean score at 12 months was 4.1, with 84.5% of scores being 4 or 5 (p < 0.005). Conclusions OPS provides good satisfaction rates. An SBCS when an OPS is not indicated mostly results in good satisfaction levels and cosmetic scores. Usually, the results remain stable after 6 months. The use of OPS allows the excision of bigger lesions and surgical specimens. Symmetrisation procedures are not always required. With the appropriate patient selection, the rate of complications is low for both OPS and SBCS. PMID:25374618

  14. Clinico-aetiologic profile of macrocytic anemias with special reference to megaloblastic anemia

    Microsoft Academic Search

    Vineetha Unnikrishnan; Tarun Kumar Dutta; Bhawana A. Badhe; Zachariah Bobby; Ashish K. Panigrahi

    2008-01-01

    Purpose of study This study was conducted to study the clinical and laboratory parameters in patients with macrocytic anemia and to determine the etiology of macrocytic anemia with special reference to megaloblastic anemia. Materials and methods This study was a cross-sectional descriptive study carried over a period of 18 months on 60 adult patients (age ?13 years) of macrocytic anemia.

  15. An integrated clinico-metabolomic model improves prediction of death in sepsis

    PubMed Central

    Langley, Raymond J.; Tsalik, Ephraim L.; van Velkinburgh, Jennifer C.; Glickman, Seth W.; Rice, Brandon J.; Wang, Chunping; Chen, Bo; Carin, Lawrence; Suarez, Arturo; Mohney, Robert P.; Freeman, Debra H.; Wang, Mu; You, Jinsam; Wulff, Jacob; Thompson, J. Will; Moseley, M. Arthur; Reisinger, Stephanie; Edmonds, Brian T.; Grinnell, Brian; Nelson, David R.; Dinwiddie, Darrell L.; Miller, Neil A.; Saunders, Carol J.; Soden, Sarah S.; Rogers, Angela J.; Gazourian, Lee; Fredenburgh, Laura E.; Massaro, Anthony F.; Baron, Rebecca M.; Choi, Augustine M.K.; Corey, G. Ralph; Ginsburg, Geoffrey S.; Cairns, Charles B.; Otero, Ronny M.; Fowler, Vance G.; Rivers, Emanuel P.; Woods, Christopher W.; Kingsmore, Stephen F.

    2014-01-01

    Sepsis is a common cause of death, but outcomes in individual patients are difficult to predict. Elucidating the molecular processes that differ between sepsis patients who survive and those who die may permit more appropriate treatments to be deployed. We examined the clinical features, and the plasma metabolome and proteome of patients with and without community-acquired sepsis, upon their arrival at hospital emergency departments and 24 hours later. The metabolomes and proteomes of patients at hospital admittance who would die differed markedly from those who would survive. The different profiles of proteins and metabolites clustered into fatty acid transport and ?-oxidation, gluconeogenesis and the citric acid cycle. They differed consistently among several sets of patients, and diverged more as death approached. In contrast, the metabolomes and proteomes of surviving patients with mild sepsis did not differ from survivors with severe sepsis or septic shock. An algorithm derived from clinical features together with measurements of seven metabolites predicted patient survival. This algorithm may help to guide the treatment of individual patients with sepsis. PMID:23884467

  16. Clinico-epidemiological study of Schistosomiasis mansoni in Waja-Timuga, District of Alamata, northern Ethiopia

    PubMed Central

    2014-01-01

    Background Intestinal schistosomiasis, caused by digenetic trematodes of the genus Schistosoma, is the most prevalent water related disease that causes considerable morbidity and mortality. Although prevalence of Schistosoma mansoni infection has been reported for the present study area, earlier studies have not estimated intensity of infections in relation to periportal fibrosis, which would have been crucial for epidemiological and clinical evaluations. Hence, a community based cross sectional study was conducted from December 2011 to March 2012 to assess prevalence of infection and schistosomal periportal fibrosis in Waja-Timuga, northern Ethiopia. Methods In a cross sectional study involving 371 randomly selected individuals, fresh stool samples were collected and processed by the Kato-Katz method and examined microscopically. Ultrasonography was used to determine status of schistosomal periportal fibrosis and to detect hepatomegaly and/or splenomegaly. Serum was collected for assay of hepatic activity. Statistical analysis was performed using STATA 11 statistical soft ware. P-value <0.05 was reported as statistically significant. Results The prevalence of S.mansoni infection was 73.9%, while the prevalence of schistosomal periportal fibrosis was 12.3% and mean intensity of infection was 234 eggs per gram of stool. Peak prevalence and intensity of S.mansoni infection was documented in the age range of 10–20 years. Among the study individuals, hepatomegaly was recorded in 3.7% and splenomegaly was recorded in 7.4% of the study individuals. Similarly, among the study individuals who had definite periportal fibrosis, 5.9% had elevated liver enzyme levels. Conclusion The high prevalence of Schistosoma mansoni infection and schistosomal periportal fibrosis observed in the study area calls for a periodic deworming program to reduce disease, morbidity and transmission. Preventive chemotherapy complemented with other control measures is highly required for sustainable control of schistosomiasis in the study area. PMID:24690404

  17. Verrucous carcinoma of the oral cavity: a clinico-pathologic appraisal of 133 cases in Indians

    Microsoft Academic Search

    K. P. Rekha; Punnya V. Angadi

    2010-01-01

    Introduction  Verrucous carcinoma (VC), a rare variant of squamous cell carcinoma is an established entity with distinctive morphology and\\u000a specific clinical behavior. To date, only a small series of head and neck verrucous carcinomas have been reported in the literature.\\u000a \\u000a \\u000a \\u000a \\u000a Materials and methods  The present study evaluated 133 cases of verrucous carcinoma for the age, sex, site of involvement, duration of disease

  18. Hypoglossal canal invasion by glomus jugulare tumors: clinico-radiological correlation.

    PubMed

    Gursoy, Merve; Orru, Emanuele; Blitz, Ari M; Carey, John P; Olivi, Alessandro; Yousem, David M

    2014-01-01

    The aim of this retrospective study is to assess the rate at which glomus jugulare tumors invade the hypoglossal canal (HC) and to correlate computed tomography (CT) and magnetic resonance imaging (MRI) findings with the clinical evidence of cranial nerve (CN) XII dysfunction. CT and MRI imaging modalities of 31 patients were blindly reviewed by an attending neuroradiologist. Imaging studies identified involvement in 22 tumors (22/31, 71.0%). Thirteen of 22 patients (59.1%) had clinically evident CN XII symptoms. Accuracy rate was 76.7% (23/30) for MRI and 78.6% (11/14) for CT. MRI showed 100% sensitivity but had only 59% specificity and the specificity for CT was 66.7%. When radiologists elucidate HC involvement, it may alter the surgical approach and may lead to more focused/accurate clinical evaluation of tongue function. PMID:25043533

  19. Clinico-investigative Profile of Patients of Hirsutism in a Tertiary Level Institution

    PubMed Central

    Sharma, Divya; Shanker, Vinay; Tegta, Gitaram; Gupta, Mudita; Verma, Ghanshyam Kumar

    2012-01-01

    Introduction: Hirsutism has a significant impact on the quality of life and serves as a marker of underlying hormonal and systemic conditions. The aim of this study was to study the clinical, biochemical characteristics of these patients and other associations. Materials and Methods: Fifty (n=50) consecutive newly diagnosed patients of hirsutism were assessed during a period from August 2009 to July 2010 using modified Ferriman Gallwey (mF-G) score. Results: Idiopathic hirsutism (IH) was found in 30 (60%) patients followed by polycystic ovarian syndrome (PCOS) in 19 (38%) patients. Other causes included late-onset classic adrenal hyperplasia in two (4%) and hypothyroidism in four (8%) patients. The mean age at presentation was 23.8±6.657 years. Total (T) and free testosterone (fT), 17-hydroxyprogesterone was significantly higher in PCOS than IH. Conclusion: The present data show IH as the commonest cause of hirsutism in our study population. Face, chest, and lower abdomen have a higher impact on the hirsutism score while upper back, abdomen, and lower back are rarely involved. PMID:23180912

  20. Classic Kaposi's sarcoma in morocco: clinico -epidemiological study at the national institute of oncology

    PubMed Central

    2011-01-01

    Background Classic Kaposi's sarcoma (CKS) is a rare disease likely associated with human herpes virus 8 (HHV-8) infection, and occurs predominantly in Jewish, Mediterranean and middle eastern men .There is a dearth of data in Moroccan patients with CKS regarding epidemiology, clinical characteristics and outcomes. This report examines a cohort of patients with CKS evaluated at the national institute of oncology over 11-year period. Methods A retrospective analysis of patients referred to the national institute of oncology with classical Kaposi sarcoma, between January 1998 and February 2008, was performed. Reviewed information included demographics, clinical and pathological staging, death or last follow-up. Results During the study period, 56 patients with a diagnosis of CKS have been referred to our hospital. There were 11(19,7%) females and 45 (80,3%) males (male-to-female ratio: 4:1). Mean age at diagnosis was 61,7 ± 15 (range: 15- 86 years). Nodules and/or plaques were the most frequent type of lesion. The most common location was the lower limbs, particularly the distal lower extremity (90%). In addition to skin involvement, visceral spread was evident in 9 cases. The most common visceral involvement sites were lymph nodes (44%), lung (22%), and gastrointestinal tract (22%). Associated lymphoedema was seen in 24 (42%) of the patients. There were 18 stage I patients (32,14%), 8: stage II (14,28%), 21 stage III(37,5%) and 9 stage IV (16,07%). A second primary malignancy was diagnosed in 6 cases (10,7%), none of the reticuloendothelial system. With a median follow-up of 45 months, 38 (67,8) patients are alive, of whom 25 (65,78%) patients with stable disease, five with progressive disease currently under systemic chemotherapy and 8(21,05%) are alive and free of disease, over a mean interval of 5 years. Conclusion This is the largest reported series in our context. In Morocco, CKS exhibits some special characteristics including a disseminated skin disease at diagnosis especially in men, a more common visceral or lymph node involvement and a less frequent association with second malignancies. PMID:22078023

  1. Excellent Functionality Despite Clinico-Radiological Deformity in Osteomyelitis Variolosa - A Case Report

    PubMed Central

    Mugalur, Aakash; Shahane, Sunil M; Samant, Ashwin; Pathak, Aditya C; Reddy, Rajeev

    2015-01-01

    Despite the eradication of smallpox from the world in 1980 the osteo-articular sequelae of smallpox are still occasionally noticed in previously endemic areas. The sequelae of osteomyelitis variolosa may raise a diagnostic challenge to the untrained eyes of the surgeon. We present a case of “osteomyelitis variolosa” in a 70 years old patient. The patient had bilateral dislocation of the elbow joint with multidirectional instability. There was distortion of the articular surfaces and ankylosis of the bilateral proximal radio-ulnar joint. Hypoplasia of the right ulna with short fourth and fifth metacarpals of the left hand and hypoplasia of right fourth metacarpal with cortical thickening was noted radiologically. The patient had minimal disability of his elbows despite the striking radiological abnormality and was functionally independent.

  2. [Topometric and clinico-dosimetric aspects of the radiotherapy of cancer of the oropharynx].

    PubMed

    Choudkhuri, F A; Vorob'eva, L V

    1988-03-01

    The use of modern diagnostic facilities led to a study of the physico-dosimetric, topometric and clinical aspects of radiotherapy of oropharyngeal cancer. The most effective approaches to therapy of oropharyngeal tumors with account of their site, spread and degrees of differentiation were developed. The most effective method was shown to be the combination of gamma-beam therapy (50 Gy) with electron-photon radiation (20 Gy) of an accelerator of 18-20 MeV, radiation exposure of normal tissues being lowered by approximately 10-20% as compared to that in gamma-beam therapy used alone. The use of the above method in 45 oropharyngeal cancer patients resulted in an immediate clinical effect (disappearance of a tumor and regional metastases (if any) in 60% of the patients. The 2-year survival rate calculated by actuarial curves, was 62 +/- 10%. PMID:3352492

  3. IgG4-related meningeal disease: clinico-pathological features and proposal for diagnostic criteria

    Microsoft Academic Search

    Katherine M. Lindstrom; John B. Cousar; M. Beatriz S. Lopes

    2010-01-01

    IgG4-related disease has evolved from originally being recognized as a form of pancreatitis to encompass diseases of numerous\\u000a organs including the hypophysis and one reported case of dural involvement. A search of the University of Virginia, Division\\u000a of Neuropathology files for 10 years identified ten cases of unexplained lymphoplasmacytic meningeal inflammation that we\\u000a then evaluated using immunohistochemical stains for IgG4 and

  4. Clinico-Immunological Profile of Children Infected with HIV Through Vertical Transmission, in Southern India

    PubMed Central

    Bairy, Indira

    2014-01-01

    Background: Karnataka, being “High Prevalent State” of southern India, the HIV infection among antenatal women has crossed 1%. There are very few reports available with CD4 count and stage wise clinical spectrum among children. The clinical spectrum among HIV infected infants and children vary in different areas of the world. Hence it is important to know the spectrum of opportunistic infections and their respective CD4 count among HIV infected children of our locality. Materials and Methods: The opportunistic infections among 31 paediatric seropositive patients were evaluated. These all patients were classified as per CDC guide lines into stage I, stage II, and stage III based on CD4 counts of > 1000cells/?l, 500-999 cells/?l,<500cells/?l respectively. The opportunistic infections were diagnosed by standard laboratory investigations. Clinical spectrum presented by each stage children was documented. Results: Children in stage I were 5(16.1%),stage II 14(45.1%) and stage III 12(38.7%). Oral candidiasis (29%) was the commonest, followed by recurrent respiratory tract infection (25.8%), tubercular lymphadenitis (16.1%) and chronic diarrhoea (12.9%). Conclusion: The present study showed the children with higher CD4 count had few infections and children with lower CD4 count presented with multiple opportunistic infections. This study also showed vertical transmission as the sole mode of transmission. PMID:25120978

  5. Posterior fossa haemangioblastomas in Northern Ireland: a clinico-epidemiological study

    PubMed Central

    Chee, C P; Bailey, I C

    1986-01-01

    A retrospective study of 25 patients who presented with posterior fossa haemangioblastomas to the Northern Ireland Regional Neurosurgical Centre over the past 25 years has been carried out. The epidemiological and clinical features and the results after operative treatment are presented and compared with other series. Posterior fossa haemangioblastomas were more common in female than in male patients and solid tumours accounted for 40% of all cases. While only two patients had associated polycythaemia, five patients (20%) were found to have persistent leucocytosis pre-operatively, while 24% had von Hippel-Lindau complex including two patients who were operated upon for an associated spinal haemangioblastoma. Of particular interest was a patient who had neurofibromatosis. There was no perioperative deaths. Patients with solid tumours fared badly in the long term compared with those who had a cystic type. PMID:3811016

  6. [Clinico-statistical studies of 700 cases of lymphopathy of various types. Nosological considerations].

    PubMed

    Visca, U; Bombara, R; Cassi, E; Pagliano, F M

    1976-02-11

    A breakdown of the statistical data for 700 cases of lymphopathy was undertaken to how far each disease picture could be considered as a seperate entity or as part of a sub-class. It was found that two possibilities exist: a) there is a typical sub-class for this nosological category; b) two sub-classes can be formed, one of which covers paranormal situations, while the other includes cases presenting pathological parameter values. In either event, there remains a considerable fringe of atypical cases that cannot be included in any sub-class. PMID:1256696

  7. Excellent Functionality Despite Clinico-Radiological Deformity in Osteomyelitis Variolosa - A Case Report.

    PubMed

    Mugalur, Aakash; Shahane, Sunil M; Samant, Ashwin; Pathak, Aditya C; Reddy, Rajeev

    2015-01-01

    Despite the eradication of smallpox from the world in 1980 the osteo-articular sequelae of smallpox are still occasionally noticed in previously endemic areas. The sequelae of osteomyelitis variolosa may raise a diagnostic challenge to the untrained eyes of the surgeon. We present a case of "osteomyelitis variolosa" in a 70 years old patient. The patient had bilateral dislocation of the elbow joint with multidirectional instability. There was distortion of the articular surfaces and ankylosis of the bilateral proximal radio-ulnar joint. Hypoplasia of the right ulna with short fourth and fifth metacarpals of the left hand and hypoplasia of right fourth metacarpal with cortical thickening was noted radiologically. The patient had minimal disability of his elbows despite the striking radiological abnormality and was functionally independent. PMID:26157526

  8. [Clinico-immunologic effectiveness of chlorophyllypt in the treatment of acute destructive pneumonia].

    PubMed

    Simvolokov, S I; Nikitin, A V; Iakovleva, L G

    1989-02-01

    An attempt has been made to replace antibiotics by chlorophyllypt (0.25 per cent solution in physiological sodium chloride solution administered by intravenous drip). The clinical, laboratory and X-ray parameters in 22 patients treated by this drug normalized in earlier terms than those in 19 patients who received the traditional antibiotic therapy. Chlorophyllypt was found to have the immunocorrective effect manifested by the normalization of the T-lymphocyte number and their theophylline-resistant subpopulation. No such an effect was achieved when broad-action antibiotics were used. PMID:2657207

  9. [Clinico-psychopathological features and dynamic aspects of long-standing and chronic endogenous depressions].

    PubMed

    Dikaia, T I

    2011-01-01

    Long-sanding depressions are defined as protracted depressive conditions lasting at least 2 years with subsequent spontaneous or therapeutic high-quality remission (intermission) and fully reversed depressive disorders, recovery of the premorbid psychic functions, personality traits and quality of life. Two variants of long-standing depressions, simple and polymorphic, are distinguished based on peculiarities of the psychopathological structure. The practicability of classification of long-standing depressions and their dynamics by phase states is discussed. Chronic depressive states are distinctive for well-apparent polymorphism of disorders and gradual aggravation of depressive symptoms up to neurosis-like and delusional register without a tendency toward spontaneous normalization and with only low-quality therapeutic remission with residual productive symptomatology. Four types of chronic depressions are distinguished: melancholic, apathoadynamic, depressive-hypochondriac, and depressive-depersonalizing. Three variants of dynamics of chronic depressions are described: dynamic-inert, dynamic-labile, and dynamic with continuous aggravation of the disorder. The appropriateness of discussion of chronic depressions in terms of protracted progressive attacks and conservation of their psychopathological basis throughout the period of the disease is considered. The principles of therapy of long-standing and chronic endogenous depressions are briefly outlined. PMID:21674920

  10. Clinico-Mycological Study of Dermatophyte Toenail Onychomycosis in New Delhi, India

    PubMed Central

    Yadav, Pravesh; Singal, Archana; Pandhi, Deepika; Das, Shukla

    2015-01-01

    Introduction: There is a constant need to define the epidemiological and mycological characteristics of onychomycosis (OM) for optimal management strategies. Objectives: To define the epidemiological and mycological characteristics of patients with dermatophyte toenail OM in a tertiary care hospital. Materials and Methods: Hundred consecutive patients of KOH and culture-positive dermatophyte toenail OM were subjected to detailed history, clinical examination and investigations. Results: Maximum number of patients (40%) belonged to 31-45 years age group and there was a male preponderance (M:F = 6.7:1). The mean duration of disease was 54 months. Thirty-three patients had fingernail involvement in addition to the toenail OM and 37% had co-existent cutaneous dermatophyte infection. Discoloration was the most common symptom (98%). Ninety-four (94%) patients had distal lateral subungual onychomycosis (DSLO) while two had superficial onychomycosis (SO) and only one had proximal superficial onychomycosis (PSO). Trichophyton interdigitale was the most common etiological agent (61%) followed by Trichophyton rubrum and Trichophyton verrucosum. Conclusions: Toenail OM is more common in males. DSLO was the most common clinical variant and T. interdigitale the most common etiological fungus responsible for toenail OM in our region. The importance of early diagnosis and treatment is highlighted as long-standing toenail OM predisposes to fingernail onychomycosis and recurrent tinea pedis. PMID:25814703

  11. Clinico-biochemical studies on acute toxic nephropathy in goats due to uranyl nitrate.

    PubMed

    Dash, P K; Joshi, H C

    1989-02-01

    Acute toxic nephropathy was produced in 6 healthy goats by injecting intravenously 1% uranyl nitrate (UN) (15 mg/kg body weight). The early painful clinical signs simulating shock progressed with subnormal temperature, slow-shallow respiration and arrhythmic pulse followed by death due to respiratory failure within 96 to 120 hr. All the affected goats had normocytic normochromic anemia, leucocytosis, neutrophilia with left shift eosinopenia, decreased monocytes and presence of 1-2% reticulocytes in the peripheral blood smears. On blood chemical analysis, a uniform and continuous rise was seen in serum creatinine with a concomitant daily increase of serum urea and uric acid. Simultaneous analysis of urine indicated polyuria leading to oliguria, acidic pH, albuminuria, glycosuria with presence of neutrophils, RBC's, epithelial and fatty casts, increase of triple phosphate, and cystine crystals reflecting acute damage of kidneys in the affected goats. PMID:2711608

  12. Clinico-Pathological Discrepancies in a General University Hospital in São Paulo, Brazil

    PubMed Central

    Kotovicz, Fabiana; Mauad, Thais; Saldiva, Paulo H. N.

    2008-01-01

    INTRODUCTION The autopsy rate has continuously diminished over the past few decades, reducing the quality of medical care and the accuracy of statistical health data. OBJECTIVE To assess the accuracy of clinical diagnoses by comparing pre- and postmortem findings, and to identify potential risk factors for misdiagnoses. METHODS Retrospective evaluations performed between June 2001 and June 2003 in a 2500-bed tertiary university hospital in São Paulo, Brazil, including 288 patients who died at that institution and had a postmortem examination. RESULTS Clinical and autopsy records were reviewed and compared for categorization using the adapted Goldman criteria. The overall major and minor discrepancy rates were 16.3% and 28.1%, respectively. The most common missed diagnoses were pulmonary embolism, pneumonia, and myocardial infarction, and the most prevalent underlying diseases were infectious diseases, cerebro-cardiovascular conditions, and malignancies. Patients age 60 or older had an increased risk of diagnostic disagreement, as did female patients. The period of hospitalization, last admission unit at the hospital and underlying disease were not significantly related to the pre-mortem diagnostic accuracy. DISCUSSION The discrepancy rate found in this study is similar to those reported globally. The factors influencing diagnostic accuracy as well as the most commonly missed diagnoses are also consistent with the literature. CONCLUSION Autopsy remains a crucial tool for improving medical care, and effort must be focused on increasing its practice worldwide. PMID:18925315

  13. Portulaca oleracea (purslane): nutritive composition and clinico-pathological effects on Nubian goats

    Microsoft Academic Search

    W. A. Obied; E. N. Mohamoud; O. S. A. Mohamed

    2003-01-01

    Feeding trials of Portulaca oleracea were conducted in two groups of Nubian goats that received the plant at daily doses of 5g\\/kg BW and ad libitum, respectively. Consumption caused weakness of the fore and hind limbs with inability to stand, greenish watery diarrhoea and polyuria. Hepatonephropathy and enteritis accompanied by alterations in some blood and serum constituents were also observed.

  14. Adrenal lipomatous tumours: a 30 year clinico- pathological experience at a single institution

    Microsoft Academic Search

    China K Y Lam

    Aims—Fatty tumours of the adrenal gland are uncommon and their features have received little attention in the literature. The aim of this study is to analyse the fea- tures of adrenal lipomatous tumours. Methods—The histological features of pri- mary adrenal tumours reported over a 30 year period (1970 to 1999) in Queen Mary Hospital, Hong Kong were reviewed and the

  15. [Clinico-psychological study of deaf children and adolescents with residual organic syndromes and oligophrenia].

    PubMed

    Saraev, S Ia

    1988-01-01

    Standard methods were employed to study clinically and psychologically 70 deaf schoolchildren with psychic developmental defects. These techniques allowed assignment of the schoolchildren to different groups by mental and cognitive capacity. Comparative assessment of clinical and psychological findings contributed to differentiation of dysontogenetic variants: mental retardation, encephalopathic forms of borderline intellectual deficiency and oligophrenia. A specific pattern of cognitive functions in deaf children should be accounted for when making differential diagnosis of clinical forms of mental deficiency in congenital and early acquired deafness. PMID:3188765

  16. [Clinico-electrophysiological study of behavior disorders in children with oligophrenia].

    PubMed

    Shipitsina, L M; Ivanov, E S

    1989-01-01

    EEG correlation analysis was performed in 32 oligophrenic children aged 8 to 12 years at a debility stage with prominent behavioral changes. Compared to healthy age-matched persons, in patients spatial potential synchronization was decreased, interhemispheric correlations prevailed over the intrahemispheric ones, the interrelations within the left hemisphere reduced not only in projection zones but also in infraparietal ones. PMID:2728748

  17. Clinico-pathological and biomolecular findings in Italian patients with multiple cutaneous neurofibromas

    PubMed Central

    2011-01-01

    Background Neurofibroma occurs as isolated or multiple lesions frequently associated with neurofibromatosis type 1 (NF1), a common autosomal dominant disorder affecting 1 in 3500 individuals. It is caused by mutations in the NF1 gene, which comprises 60 exons and is located on chromosome 17q11.2. NF1 is a fully penetrant gene exhibiting a mutation rate some 10-fold higher compared with most other disease genes. As a consequence, a high number of cases (up to 50%) are sporadic. Mutation detection is complex due to the large size of the NF1 gene, the presence of pseudogenes and the great variety of lesions. Methods 110 patients with at least two neurofibroma lesions recorded in the files of the Pathology Department of the University of Modena during the period 1999-2010, were included in this study. Through interviews and examination of clinical charts, pedigrees were drawn for all patients who were affected by at least two neurofibromas. We attempted to delineate the clinical features of NF1 and the mutational spectrum in the cohort of 11 NF1 families identified. For each proband, the whole coding sequence and all splice sites were studied for mutations, either by the protein truncation test (PTT), or, more frequently, by denaturing high performance liquid chromatography (DHPLC). Two GIST tumors of NF1 patients were tested for somatic NF1 mutations. Results NF1 germline mutations were identified in 7 (68%) patients. A novel mutation, c.3457_3460delCTCA in exon 20, was detected in two unrelated patients and was associated with different clinical features. No NF1 somatic mutations were detected in the GIST tumors. A wide phenotypic and genotypic variability was registered, both in the spectrum of skin lesions and visceral neoplasms, even among members of the same family who had different clinical manifestations. A proclivity to multiple tumors arising in the same subject, and a higher tumor burden per family were the most relevant findings observed in patients affected with the NF1 mutation. Conclusions We report a novel NF1 mutation and we contribute data for the refinement of the NF1 genotype-phenotype spectrum. PMID:21838856

  18. Clinico-microbiological review of non-contact-lens-associated acanthamoeba keratitis.

    PubMed

    Jain, Rajat; Garg, Prashant; Motukupally, Swapna Reddy; Geary, Michael B

    2015-07-01

    Clinical/microbiological records of 194 patients with microbiological/histopathological diagnosis of Acanthamoeba keratitis from 2007-11 without history of contact lens wear were retrospectively studied. Positive results on corneal scraping and culture were analyzed. Patients were divided based on positive first smear report (group 1/2) and time of presentation (group 3/4). Primary and secondary outcome measures were microbiological positivity rate and to find any possible differences at presentation in sub-groups, respectively. Mean age of patients was 38.5?±?13.7 years, M:F was 1.8:1. Positivity of first smear examination was 82% and was 98% overall in three scrapings. Ten percent potassium hydroxide with calcoflur white was better than Grams stain (87.1 versus 71.1%). Culture was positive in 79.4% cases. Sub-group analysis showed clinically/demographically similar groups 1 and 2 (p?>?0.05). Patients who presented within a month of symptoms (group 3) were significantly younger than others (p?=?0.012). Microscopic diagnosis of non-contact-lens Acanthamoeba keratitis is reliable. PMID:24251436

  19. [Clinico-genealogic study of patients with unfavorable early infantile schizophrenia].

    PubMed

    Kozlova, I A

    1979-01-01

    The paper concerns similarities and differences between childhood schizophrenia and schizophrenia of the adults from the standpoint of the genealogical background in the respective families. The degree of loading by manifest psychoses and the typology of nonmanifest disturbances among the parents of probands with an unfavorable development of early childhood schizophrenia was studied. The data obtained demonstrate heterogeneity of this form of childhood schizophrenia, confirmed as well by genealogical studies in a comparative age aspect. PMID:494919

  20. Demographic and Clinico-Epidemiological Features of Dengue Fever in Faisalabad, Pakistan

    PubMed Central

    Raza, Faiz Ahmed; Rehman, Shafiq ur; Khalid, Ruqyya; Ahmad, Jameel; Ashraf, Sajjad; Iqbal, Mazhar; Hasnain, Shahida

    2014-01-01

    This cross-sectional study was carried out to explore the epidemiological and clinical features of dengue fever in Faisalabad, Pakistan during 2011 and 2012. During the study period, anti-dengue IgM positive cases were reported in the post-monsoon period during the months of August–December. Certain hotspots for the dengue infection were identified in the city that coincide with the clusters of densely populated urban regions of the city. Out of total 299 IgM positive patients (male 218 and female 81); there were 239 dengue fever (DF) and 60 dengue hemorrhagic fever (DHF) patients. There was decrease in the median age of dengue patients from 31 years in 2011 to 21.5 years in 2012 (p<0.001). Abdominal pain was seen in 35% DHF patients followed by nausea in 28.3%, epistaxis in 25% and rash in 20% patients (p<0.05). Patients reported to be suffering from high-grade fever for an average of 8.83 days in DHF as compared to 5.82 days in DF before being hospitalized. Co-morbidities were found to be risk factor for the development of DHF in dengue patients. Clinical and laboratory features of dengue cases studied could be used for the early identification of patients at risk of severe dengue fever. PMID:24595236

  1. Evaluation of clinico-epidemiological and histopathological features of pityriasis rosea

    PubMed Central

    Özyürek, Gaye Devrim; Çenesizo?lu, Erol

    2014-01-01

    Introduction Pityriasis rosea is a sudden-onset and self limiting disease with specific skin rash. The exact etiology is still not clear. Aim To determine epidemiological, etiological, clinical and histopathological features in pityriasis rosea (PR). Material and methods Fifty two patients (older than 18 years) with PR were included in this study. Patients were examined for epidemiological and etiological features. Biopsy specimens obtained from secondary eruptions were histopathologically evaluated with hematoxylin-eosine and immunohistochemically evaluated with CD3 and CD20 monoclonal antibodies. Results Age range of patients was 18–53, mean age was 29.3 ±9.5 and women-to-men ratio was 1.08/1. Thirty-nine (75%) patients had a history of wearing new clothes, 27 (51.9%) patients had a history of recent respiratory tract infection, 15 (28.8%) patients had a history of recent gastrointestinal infection. Eczematous changes were detected in biopsy materials by histopathological evaluation, and cellular infiltrate was positively stained with pan T-cell marker CD3 and negatively stained with B lymphocyte marker CD20 in all biopsy materials in immunohistochemical examination. Conclusions In our study, frequency of pre-disease infection and prodromal symptoms history were determined to be higher than the results of similar studies in the literature. These higher results suggest that PR may be delayed-type hypersensitivity to an infectious factor. However, positive staining of all biopsy materials with pan T lymphocyte marker CD3 supports the association with cellular immunity. We believe that more extensive studies are needed on this issue. PMID:25254006

  2. [Clinical and social adaptation of patients with paroxysmal schizophrenia (clinico-epidemiologic study)].

    PubMed

    Krasik, E D; Logvinovich, G V

    1987-01-01

    In 186 patients with paroxysmal schizophrenia the authors analyzed their social relations and functions as compared with a premorbid period. Four compensated and three decompensated levels of social adaptation have been identified. Variants of combination of clinical and social levels of adaptation are systematized in the form of four types. It has been established that integrative and destructive types of adaptation develop in patients with partial or complete correlation of clinical and social characteristics. Extrovert and introvert types reflect contrast combinations of clinical and social levels of adaptation. The results are of interest for examination of the mechanisms of adaptation formation and optimization of rehabilitation programmes. PMID:3618043

  3. Clinico-pathological evaluation of restrictive cardiomyopathy (endomyocardial fibrosis and idiopathic restrictive cardiomyopathy) in India

    Microsoft Academic Search

    Sandeep Seth; K. K. Talwar

    Background: Restrictive heart disease is characterized by impairment of ventricular filling during diastole with preserved systolic function. The clinical and histopathological profile on endomyocardial biopsy of a cohort of patients with restrictive cardiomyopathy (RCM) is presented. Methodology: The medical records of patients presenting with heart failure with systemic congestion, subsequently diagnosed as restrictive heart disease after evaluation including cardiac catheterisation,

  4. Infected foot ulcers in male and female diabetic patients: a clinico-bioinformative study

    Microsoft Academic Search

    Shazi Shakil; Asad U Khan

    2010-01-01

    BACKGROUND: The study aimed at (i) characterizing the mode of transmission of blaCTX-M and blaTEM-1 among extended-spectrum-?-lactamase (ESBL)-producing Escherichia coli strains isolated from infected diabetic foot ulcers, and (ii) identifying the risk factors for \\

  5. [Disseminated Pneumocystis carinii infection: clinico-pathologic findings in an AIDS patient].

    PubMed

    Valdès, E; Borzoni, F; Onnis, D; Piras, S; Vespa, A; Varsi, C

    1994-12-01

    Pneumocystis carinii pneumonia (PcP) is the most frequent cause of death in AIDS patients. Systemic diffusion of this microorganism is a rare event, mostly reported in patients receiving prophylactic aerosol therapy. The case here described is relative to a 29 years old man with AIDS, dead short by after hospital admission. Radiological and ecoscan examinations revealed structural subversion of liver and spleen, with frequent parenchymal calcification. Post mortem histological examination of lung, liver, spleen, heart, bone marrow, lymph nodes, kidney and hypophysis identified the presence of Pc, confirmed by monoclonal specified antibody immunostaining. PMID:7617399

  6. [Clinico-morphological characteristics of injuries inflicted by shots from weapons of non-lethal action].

    PubMed

    Lazarev, S M; Babakhanian, A R

    2004-01-01

    The problem of studying injuries inflicted by different kinds of self-defense weapons is of great interest both to medical workers of different specialties (experts in forensic medicine, surgeons, toxicologists etc.) and to criminologists. Cases from practice of clinical and forensic medicine show that shots from pistols PB-4 with cartridges of traumatic action depending on the distance and the injured area as well as on other dynamic parameters of the interaction of the shell and the obstacle can cause injuries of different degrees of severity. PMID:15143587

  7. Effects of commonly used NSAID's on gastric mucosa. A clinico-endoscopic and histopathological study.

    PubMed

    Misra, R; Pandey, H; Chandra, M; Chandra, M; Agarwal, P K; Pandeya, S N

    1990-12-01

    Non steroidal anti-inflammatory drugs (NSAID's) are one of the most commonly used agents in clinical practice today. All these drugs are known to produce gastro-intestinal lesions. In the present study we found that aspirin, indomethacin and phenylbutazone caused gastric mucosal damage in 90.9%, 100%, respectively while ibuprofen and paracetamol caused gastric mucosal damage in 33.3% and 37.5% respectively. Thus latter two drugs were safer NSAID's. Further more we have demonstrated that endoscopic monitoring of the patients on NSAID's is a sensitive method of early detection of gastric mucosal damage. This monitoring may be particularly valuable in high risk subjects on NSAID's. PMID:2096127

  8. Clinico-radiologic findings of entrapped inferior oblique muscle in a fracture of the orbital floor.

    PubMed

    Kim, Soo; Kim, Taik-Kun; Kim, Seung-Hyun

    2009-09-01

    A 51-year old man presented with vertical and torsional diplopia after reduction of a blowout fracture at another hospital one year ago. He had no anormalies of head position and 14 prism diopters (PD) right hypertropia (RHT) in the primary position. In upgaze no vertical deviation was found, and hyperdeviation on downgaze was 35PD. Bielschowsky head tilt test showed a negative response. Distinct superior oblique (SO) and inferior rectus (IR) underaction of the right eye was noted but IO overaction was mild on the ocular version test. Double Maddox rod test (DMRT) revealed 10-degree extorsion, but fundus extorsion was minimal in the right eye.Thin-section coronal CT scan showed that there was no fracture line on the anterior orbital floor, but a fracture remained on the posterior orbital floor. Also, the anterior part of the right inferior oblique muscle was vertically reoriented and the medial portion of the inferior oblique muscle was not traced on the coronal CT scan. The patient underwent 14 mm right IO recession and 3 mm right IR resection. One month after the surgery, his vertical and torsional diplopia were eliminated in the primary position. PMID:19794954

  9. Clinico-Radiologic Findings of Entrapped Inferior Oblique Muscle in a Fracture of the Orbital Floor

    PubMed Central

    Kim, Soo; Kim, Taik-Kun

    2009-01-01

    A 51-year old man presented with vertical and torsional diplopia after reduction of a blowout fracture at another hospital one year ago. He had no anormalies of head position and 14 prism diopters (PD) right hypertropia (RHT) in the primary position. In upgaze no vertical deviation was found, and hyperdeviation on downgaze was 35PD. Bielschowsky head tilt test showed a negative response. Distinct superior oblique (SO) and inferior rectus (IR) underaction of the right eye was noted but IO overaction was mild on the ocular version test. Double Maddox rod test (DMRT) revealed 10-degree extorsion, but fundus extorsion was minimal in the right eye. Thin-section coronal CT scan showed that there was no fracture line on the anterior orbital floor, but a fracture remained on the posterior orbital floor. Also, the anterior part of the right inferior oblique muscle was vertically reoriented and the medial portion of the inferior oblique muscle was not traced on the coronal CT scan. The patient underwent 14 mm right IO recession and 3 mm right IR resection. One month after the surgery, his vertical and torsional diplopia were eliminated in the primary position. PMID:19794954

  10. Clinico-radiological profile and nuances in the management of cervicomedullary junction intramedullary tumors

    PubMed Central

    Nair, Anup P.; Mehrotra, Anant; Das, Kuntal Kanti; Srivastava, Arun K.; Sahu, Rabi Narayan; Kumar, Raj

    2014-01-01

    Background: Cervicomedullary junction (CMJ) intramedullary tumors comprise of tumors that often pose a surgical challenge even in the present era. Though classified under brainstem glioma CMJ tumors are well amenable for surgical resection and have a good outcome. Various factors are involved in the outcome of these patients following surgery and a proper pre-operative assessment is often required to reduce the morbidity and mortality. Materials and Methods: Patients admitted in the Department of Neurosurgery with a diagnosis of CMJ intramedullary tumors from January 2001 to January 2010 were included in the study. Patients were analyzed retrospectively regarding their symptomatology, clinical findings, radiology and outcome after surgery. All patients underwent pre-operative magnetic resonance imaging (MRI) and post-operatively all were managed in the neurosurgery intensive care unit for days to weeks or as dictated by the clinical condition of the patient. Results: A total of 32 patients were included in the present study. The number of males was 21 (65.6%) and females were 11 (34.4%) respectively. The mean age of presentation was 22.97 ± 9.8 years and the mean duration of pre-operative symptoms was 13.3 ± 12.9 months. The tumor had extension from the CMJ into the cervical region in 17 (53.1%) and into the medullary region in 14 (43.8%) patients. Tumor decompression was done in 9 (28.1%) patients and gross near total excision done in 23 (71.87%) patients. Conclusions: Cervicomedullary tumors are a subset of tumors quite distinct from the usual brainstem tumors. Patients having predominant cervical involvement present early and have less post-operative deficits. Those with predominantly more medullary involvement present late, hence have a much more morbid outcome. Though closely related to vital neural structures, surgery forms the mainstay of treatment. Adequate pre-operative planning and preparation of the patient along with intense post-operative monitoring and ventilatory assistance as and when required helps in a good surgical outcome. PMID:24891886

  11. RET/PTC Translocations and Clinico-Pathological Features in Human Papillary Thyroid Carcinoma

    PubMed Central

    Romei, Cristina; Elisei, Rossella

    2012-01-01

    Thyroid carcinoma is the most frequent endocrine cancer accounting for 5–10% of thyroid nodules. Papillary histotype (PTC) is the most prevalent form accounting for 80% of all thyroid carcinoma. Although much is known about its epidemiology, pathogenesis, clinical, and biological behavior, the only documented risk factor for PTC is the ionizing radiation exposure. Rearrangements of the Rearranged during Transfection (RET) proto-oncogene are found in PTC and have been shown to play a pathogenic role. The first RET rearrangement, named RET/PTC, was discovered in 1987. This rearrangement constitutively activates the transcription of the RET tyrosine-kinase domain in follicular cell, thus triggering the signaling along the MAPK pathway and an uncontrolled proliferation. Up to now, 13 different types of RET/PTC rearrangements have been reported but the two most common are RET/PTC1 and RET/PTC3. Ionizing radiations are responsible for the generation of RET/PTC rearrangements, as supported by in vitro studies and by the evidence that RET/PTC, and particularly RET/PTC3, are highly prevalent in radiation induced PTC. However, many thyroid tumors without any history of radiation exposure harbor similar RET rearrangements. The overall prevalence of RET/PTC rearrangements varies from 20 to 70% of PTCs and they are more frequent in childhood than in adulthood thyroid cancer. Controversial data have been reported on the relationship between RET/PTC rearrangements and the PTC prognosis. RET/PTC3 is usually associated with a more aggressive phenotype and in particular with a greater tumor size, the solid variant, and a more advanced stage at diagnosis which are all poor prognostic factors. In contrast, RET/PTC1 rearrangement does not correlate with any clinical–pathological characteristics of PTC. Moreover, the RET protein and mRNA expression level did not show any correlation with the outcome of patients with PTC and no correlation between RET/PTC rearrangements and the expression level of the thyroid differentiation genes was observed. Recently, a diagnostic role of RET/PTC rearrangements has been proposed. It can be searched for in the mRNA extracted from cytological sample especially in case with indeterminate cytology. However, both the fact that it can be present in a not negligible percentage of benign cases and the technical challenge in extracting mRNA from cytological material makes this procedure not applicable at routine level, at least for the moment. PMID:22654872

  12. [The clinico-epidemiological characteristics of Powassan encephalitis in the southern Soviet Far East].

    PubMed

    Leonova, G N; Sorokina, M N; Krugliak, S P

    1991-03-01

    The present communication deals with the analysis of 14 cases of Powassan encephalitis. As shown in this study, the course of this infection may be accompanied by symptoms indicating the presence of cerebral and meningeal lesions (in 7 cases meningoencephalitic forms with one fatal outcome and in 2 cases meningeal forms were registered) or take febrile and inapparent forms (5 cases). Powassan encephalitis was found to give characteristic symptoms of cerebellovestibular lesions, differentiating this disease from tick-borne encephalitis (TBE). The cases of mixed infections caused by TBE virus, Powassan encephalitis virus and tick-born Borrelia were found to be possible. PMID:1651637

  13. Clinico-biochemical and therapeutic studies on notoedric mange in pet rabbits.

    PubMed

    Galdhar, C N; Khangal, P S; Pawar, M L; Rasal, T D; Digraskar, S U

    2015-03-01

    Two male and two female pet rabbits of about 1 year of age, naturally infested with Notoedres cuniculi were studied in the present investigation. Clinical examination revealed presence of crustaceous lesions on the head, ear pinnae, both the limbs and external genitalia. Microscopic examination of skin scrapings confirmed presence of Notoedres mange infestation. Biochemical parameters revealed altered values of total serum protein, albumin, globulin, and activities of aspartate amino transferase, alanine amino transferase and alkaline phosphatase respectively. The affected rabbits were treated with two injections of Ivermectin (400 ?g/kg, subcutaneously, at interval of 15 days) along with supportive therapy. This treatment showed appreciable improvement in clinical signs and restoration in biochemical parameters. PMID:25698873

  14. Hereditary spastic paraplegia: clinico-pathologic features and emerging molecular mechanisms.

    PubMed

    Fink, John K

    2013-09-01

    Hereditary spastic paraplegia (HSP) is a syndrome designation describing inherited disorders in which lower extremity weakness and spasticity are the predominant symptoms. There are more than 50 genetic types of HSP. HSP affects individuals of diverse ethnic groups with prevalence estimates ranging from 1.2 to 9.6 per 100,000. Symptoms may begin at any age. Gait impairment that begins after childhood usually worsens very slowly over many years. Gait impairment that begins in infancy and early childhood may not worsen significantly. Postmortem studies consistently identify degeneration of corticospinal tract axons (maximal in the thoracic spinal cord) and degeneration of fasciculus gracilis fibers (maximal in the cervico-medullary region). HSP syndromes thus appear to involve motor-sensory axon degeneration affecting predominantly (but not exclusively) the distal ends of long central nervous system (CNS) axons. In general, proteins encoded by HSP genes have diverse functions including (1) axon transport (e.g. SPG30/KIF1A, SPG10/KIF5A and possibly SPG4/Spastin); (2) endoplasmic reticulum morphology (e.g. SPG3A/Atlastin, SPG4/Spastin, SPG12/reticulon 2, and SPG31/REEP1, all of which interact); (3) mitochondrial function (e.g. SPG13/chaperonin 60/heat-shock protein 60, SPG7/paraplegin; and mitochondrial ATP6); (4) myelin formation (e.g. SPG2/Proteolipid protein and SPG42/Connexin 47); (5) protein folding and ER-stress response (SPG6/NIPA1, SPG8/K1AA0196 (Strumpellin), SGP17/BSCL2 (Seipin), "mutilating sensory neuropathy with spastic paraplegia" owing to CcT5 mutation and presumably SPG18/ERLIN2); (6) corticospinal tract and other neurodevelopment (e.g. SPG1/L1 cell adhesion molecule and SPG22/thyroid transporter MCT8); (7) fatty acid and phospholipid metabolism (e.g. SPG28/DDHD1, SPG35/FA2H, SPG39/NTE, SPG54/DDHD2, and SPG56/CYP2U1); and (8) endosome membrane trafficking and vesicle formation (e.g. SPG47/AP4B1, SPG48/KIAA0415, SPG50/AP4M1, SPG51/AP4E, SPG52/AP4S1, and VSPG53/VPS37A). The availability of animal models (including bovine, murine, zebrafish, Drosophila, and C. elegans) for many types of HSP permits exploration of disease mechanisms and potential treatments. This review highlights emerging concepts of this large group of clinically similar disorders. PMID:23897027

  15. 76 FR 54533 - Pipeline Safety: Issuance of Draft Decision on GexCon US, Inc. Petition for Approval of Flame...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ...Decision on GexCon US, Inc. Petition for Approval of Flame Acceleration Simulator AGENCY: Pipeline and Hazardous Materials Safety...Decision on GexCon US, Inc.'s petition for approval of Flame Acceleration Simulator (FLACS). The Draft Decision is available...

  16. PHILOSOPHICAL MAGAZINE B, 2002, VOL. 82, NO. 5, 507515 Study of the b relaxation in supercooled conned water

    E-print Network

    Tuscia, Università Degli Studi Della

    water is modi®ed by the interactions with hydrophilic and hydrophobic substrates at diOEerent levels on water con®ned in Vycor glass has been performed to test the behaviour of the hydrogen dynamics against is not in its bulk form but is in contact with substrates or ®lls small cavities. Everyday examples are water

  17. La responsabilidad social Empresarial –RSE- con enfoque ambiental en las medianas y grandes empresas del municipio de Villavicencio

    Microsoft Academic Search

    Leidy Susana Ramirez; Diana Milena Rivera Rozo

    2011-01-01

    Este artículo analiza el nivel de conocimiento y aplicación de la responsabilidad social –RSE - con enfoque ambiental en las medianas y grandes empresas del Municipio de Villavicencio. Con este objetivo se estima la aplicación de una encuesta a las empresas comerciales, industriales y de servicios que fueron clasificadas a través de una muestra estratificada y seleccionadas de forma aleatoria.

  18. Para mayor informacin sobre E-Verify, favor ponerse en contacto con la oficina del DHS llamando al

    E-print Network

    Para mayor información sobre E-Verify, favor ponerse en contacto con la oficina del DHS llamando al necesario, al Departamento de Seguridad Nacional (DHS), información obtenida del Formulario I-9 contacto con la oficina del SSA y, o el DHS antes de tomar una determinación adversa en contra suya

  19. Añadir quimioterapia después de la radioterapia mejora la supervivencia de adultos con un tipo de tumor cerebral de crecimiento lento

    Cancer.gov

    Adultos con gliomas de grado bajo, una forma de tumor cerebral, que recibieron tratamiento con quimioterapia después de la radioterapia vivieron más tiempo que pacientes que recibieron solo radioterapia, según los resultados de seguimiento a largo plazo de un estudio clínico aleatorizado y controlado, subvencionado por los NIH.

  20. Medición de placas astrométricas obtenidas con el telescopio Astrográfico de La Plata

    NASA Astrophysics Data System (ADS)

    di Sisto, R. P.; Orellana, R.

    El Observatorio de La Plata cuenta con un gran número de placas de asteroides y cometas obtenidas con el telescopio astrográfico, que cubren gran parte del cielo del hemisferio sur. En 1996 se recopilaron y clasificaron 2187 placas (Beca para estudiantes de la AAA 1996) de las cuales 2031 corresponden a asteroides. Los datos de cada placa se volcaron en una base de datos creada para facilitar su manejo y preservar la información. A partir de este trabajo se revisaron los MPC electrónicos y se identificaron aquellas placas de asteroides pertenecientes a nuestra base de datos cuyos resultados no fueron publicados en los mismos. De un total de 400 placas que no aparecían publicadas sobresalía un paquete constituído por 40 placas obtenidas en 1977. Estas últimas fueron reducidas utilizando las posiciones y movimientos propios de las estrellas de referencia obtenidas del catálogo SAO 2000 dadas para el sistema FK5. Las posiciones calculadas fueron enviadas y publicadas en los Minor Planet Circulars (MPC).

  1. The ConStratO model of handover: a tool to support technology design and evaluation

    Microsoft Academic Search

    Rebecca Randell; Stephanie Wilson; Peter Woodward; Julia Galliers

    2011-01-01

    Handovers are a specific kind of multi-disciplinary team meeting. Shift handovers and transfers are both regular features of hospital work but there is currently great variation in how such handovers are conducted, presenting a challenge for those seeking to develop technology to support handover. This article presents the ConStratO model of handover, which captures aspects of the context that influence

  2. Maxima verosimilitud Tenemos una variable X discreta con funcion de masa

    E-print Network

    Fernández Gallardo, Pablo

    M´axima verosimilitud Tenemos una variable X discreta con funci´on de masa f (x; ), donde x A y #12;Llamamos funci´on de verosimilitud a la funci´on V V (; x1, . . . , xn) = n i=1 f (xi ln(f (xi ; )), la log-verosimilitud. Las funciones V y LV alcanzan el m´aximo en el mismo punto de

  3. Deficiencias del test de la razon de verosimilitud para contrastar ciertas hipotesis con restricciones de orden

    Microsoft Academic Search

    José A. Menéndez Fernández; Bonifacio Salvador González

    1987-01-01

    Resumen  En este trabajo se estudian problemas de test de hipótesis para el vector de las medias de poblaciones normales independientes\\u000a con varianzas conocidas, cuando ambas, la hipótesis nula y la alternativa, imponen restricciones de orden sobre los parámetros.\\u000a \\u000a Se demuestra que para las hipótesis planteadas el test de razón de verosimilitud (TRV) está dominado por otro TRV para hipótesis\\u000a que

  4. Agent-Oriented Requirements Engineering Using ConGolog and i

    Microsoft Academic Search

    Xiyun Wang; Yves Lespérance

    2001-01-01

    Agent-oriented approaches are becoming popular in software engineering, both as architectural frameworks, and as modeling frameworks for requirements engineering and design. i* is an informal diagram-based language for early-phase requirements engineering that supports the modeling of social dependencies between agents and how process design choices affect the agents' goals both functional and non-functional. ConGolog is an expressive logic-based formalism for

  5. CyliCon: software package for 3D reconstruction of industrial pipelines

    Microsoft Academic Search

    N. Navab; N. Craft; S. Bauer; A. Bani-Hashemi

    1998-01-01

    As-built reconstruction of existing industrial facilities such as power plants still involves much interactive work even though photogrammetry techniques are greatly used in this process. The majority of existing systems are based on 3D-point reconstruction. In general, these systems only use epipolar geometry to help the user. CyliCon is a software package for 3D reconstruction of industrial pipelines. This software

  6. De Cuentos de hadas, Uruguay y otros sueños: Entrevista con Raquel Diana

    E-print Network

    Bravo-Elizondo, Pedro

    1999-10-01

    FALL 1999 145 De Cuentos de hadas, Uruguay y otros sueños: Entrevista con Raquel Diana Pedro Bravo-Elizondo Pasaron treinta años después que Vladimir Propp completara su Morfología del cuento (1928) referida a las narraciones folklóricas para... mi pensamiento, buscar libros y me sirve mucho 146 LATIN AMERICAN THEATRE REVIEW para escribir, me entrega otra visión de las cosas, del mundo. A veces, en un parlamento busco en Sócrates o Schopenhauer ideas que pueda emplear. En Uruguay...

  7. Video Phone 4.3 Inch LCD Display, Touch Screen , RemoCon

    E-print Network

    time Protocol (NTP) Support #12;10 Information & Status IrDA RemoCon Menu Status #12;11 AV Setup OSD · Industry Standard IP based Network Protocol Features APOS AddPac PSTN FXO S-Video Out USB Interface RCA (2 x 3.5mm Stereo Female Connector) (Mic/Line In, Line Out (Head Phone)) · VoIP based Signaling

  8. Dise~no de redes en chip de proposito especifico con informacion de rutado fisico

    E-print Network

    De Micheli, Giovanni

    Dise~no de redes en chip de prop´osito espec´ifico con informaci´on de rutado f´isico David Atienza Sistemas en Chip (SoCs), recientemente se ha propuesto el nuevo paradigma de Redes en Chip (NoCs) para So´iculo presentamos una nueva metodolog´ia de dise~no para NoCs a medida, que tiene en consideraci´on la informaci´on

  9. ConKMeL: a contextual knowledge management framework to support multimedia e-Learning

    Microsoft Academic Search

    Weihong Huang; Alain Mille

    2006-01-01

    As the latest stage of learning and training evolution, e-Learning is supposed to provide intelligent functionalities not only in processing multi-media education resources but also in supporting context-sensitive pedagogical education processes. Towards providing an integrated solution for intelligent multimedia e-Learning, this paper presents a context-aware knowledge management framework named ConKMeL. Proposed framework features a semantic context-based approach for representing and

  10. Estrategias de aprendizaje en estudiantes de enseñanza secundaria obligatoria y su relación con la autoestima

    Microsoft Academic Search

    José J. Gázquez; María del Carmen Pérez; María Isabel Ruiz; Francisco Miras; Florencio Vicente

    Learning strategies in secondary-school students and relationship with self-steem. A con- siderable number of studies have been published providing data in support of the hypothesis of a relationship between pupils' self-image and the selection and\\/or use of learning strategies. The main objective of the present work was to examine this hypothesis by exploring the relationship between high scores in self-esteem

  11. Composition-Tuned ConSi Nanowires: Location-Selective Simultaneous Growth

    E-print Network

    Kim, Bongsoo

    structuresOsimple cubic (CoSi), orthorhombic (Co2Si), and face-centered cu- bic (fcc) (Co3SiOsimple cubic (CoSi), orthorhombic (Co2Si), and face-centered cubic (Co3Si)Ofollowing a composition change. Con and detailed crystal structure of single-crystalline Co2Si and Co3Si are reported for the first time including

  12. Structure, stratigraphy and petroleum geology of the south east Nam Con Son Basin, offshore Vietnam

    SciTech Connect

    Fraser, A.J.; Matthews, S.J.; Lowe, S.; Todd, S.P.; Simon, P. Peel, F.J. [BP Exploration Operating Co., Ltd., Uxbridge (United Kingdom)

    1996-12-31

    Recent exploration of the south east Nam Con Son Basin, offshore Vietnam, by BP in alliance with Statoil has involved acquisition of new seismic and well data. These new data have allowed re-evaluation of the tectono-stratigraphic development and petroleum geology, and have provided additional constraints on the regional tectonic evolution. The offshore Vietnamese basins have evolved in response to the complex relative motions of Indochina, Peninsular Malaysia, Borneo and the South China Sea during the Cenozoic. On the regional scale these motions have been accommodated by strike-slip fault development, rifting and contraction. In the Nam Con Son Basin these motions have interacted in different ways from the Palaeogene to recent. Two rifting episodes are recognized; a Palaeogene phase dominated by E-W trending extensional faults, and a Miocene phase dominated by N-S to NE-SW trending faults. The structural evolution is complicated by a pulse of mild contraction during the Middle Miocene. The sedimentary fill of the basin evolves from continental fluvio-lacustrine in the Palaeogene through to fully marine following the second phase of rifting in the Miocene. This pulsed structural and stratigraphic evolution has resulted in basinwide deposition of source, reservoir and seal facies, and produced a variety of potential trapping styles. This paper describes the hydrocarbon habitat of the south east Nam Con Son Basin within the context of the regional tectono-stratigraphic model.

  13. Structure, stratigraphy and petroleum geology of the south east Nam Con Son Basin, offshore Vietnam

    SciTech Connect

    Fraser, A.J.; Matthews, S.J.; Lowe, S.; Todd, S.P.; Simon, P. Peel, F.J. (BP Exploration Operating Co., Ltd., Uxbridge (United Kingdom))

    1996-01-01

    Recent exploration of the south east Nam Con Son Basin, offshore Vietnam, by BP in alliance with Statoil has involved acquisition of new seismic and well data. These new data have allowed re-evaluation of the tectono-stratigraphic development and petroleum geology, and have provided additional constraints on the regional tectonic evolution. The offshore Vietnamese basins have evolved in response to the complex relative motions of Indochina, Peninsular Malaysia, Borneo and the South China Sea during the Cenozoic. On the regional scale these motions have been accommodated by strike-slip fault development, rifting and contraction. In the Nam Con Son Basin these motions have interacted in different ways from the Palaeogene to recent. Two rifting episodes are recognized; a Palaeogene phase dominated by E-W trending extensional faults, and a Miocene phase dominated by N-S to NE-SW trending faults. The structural evolution is complicated by a pulse of mild contraction during the Middle Miocene. The sedimentary fill of the basin evolves from continental fluvio-lacustrine in the Palaeogene through to fully marine following the second phase of rifting in the Miocene. This pulsed structural and stratigraphic evolution has resulted in basinwide deposition of source, reservoir and seal facies, and produced a variety of potential trapping styles. This paper describes the hydrocarbon habitat of the south east Nam Con Son Basin within the context of the regional tectono-stratigraphic model.

  14. Con-T[M8Q] potently attenuates the expression and development of morphine tolerance in mice.

    PubMed

    Ren, Baolan; Zhou, Zhijie; Liu, Zhuguo; Li, Bailin; Ou, Jie; Dai, Qiuyun

    2015-06-15

    As a variant of peptide conantokin-T (con-T), con-T[M8Q] is derived from the venom of Conus tulipa. Our previous study has demonstrated that con-T[M8Q] selectively targets N-methyl-d-aspartate receptor (NMDAR) NR2B subunit. In the present study, we determined the effects of con-T[M8Q] on the expression and development of morphine tolerance using hot plate test and acetic acid writhing test. Our results demonstrated that con-T[M8Q] could efficiently attenuate the expression and development of morphine analgesic tolerance in mice at low doses (5-20nmol/kg), and it exhibited more potent effects compared with ifenprodil, a typical small-molecule antagonist of NMDAR. In addition, low doses of con-T[M8Q] (5-20nmol/kg) did not cause drug resistance and apparent analgesic activity compared with morphine. Taken together, con-T[M8Q] could be a promising new candidate in attenuating morphine tolerance. PMID:25896730

  15. Con_A-carbone nanotube conjugate with short wave near-infrared laser ablation for tumor therapy

    NASA Astrophysics Data System (ADS)

    Lei, Huan-Yao; Peng, Ching-An; Tang, Ming-Jer; Reindhart, Kit; Szu, Harold H.

    2009-04-01

    Using the characteristics of T cell mitogen called lectin protein from the jack-beam Canavalia ensiformis Concanavalin A (Con_A) with dual activities, cytotoxicity and immunomodulation, we have shown it has a therapeutic effect on hepatoma. Injection of Con_A can eradicate the established malign tumor, because Con_A can induce tumor cell autophagic, cell-programmed death, as well as activate the effector T cells. Combined, in this paper, with the absorption exceeding the Carbon NanoTube (CNT) band-gap (?bg=~1/CNT diameter) with an active short wave near-infrared (SWIR) (1.2~1.5 micron wavelengths), which happened to be translucent to the irradiation upon animal skin, similar to that used in hospital fingertip-clamped Pulse Oxymetry. Once the Con_ACNT is guided to hepatoma cells, it is bonded and internalized into the mitochondria (MC) compartment, the cellular energy factory. Con_A has the higher specificity for tumor cells useful for targeting because of the abnormal glycosylation on tumor cells. When CNT hitch hike with Con_A, they can t together like a laser-denotable chemical missile surgically targeting at the tumor cells precisely by Con_A-guidance. We switch on SWIR laser, when the Con_A-CNT conjugated complex has been bonded and internalized to MC of malign cells and already commenced cellular programmed death. Thus, it might appear to casual readers that we have initiated an overkill, chemical drugged autophage followed with physical laser ablation, but what if we can eradicate hepatoma totally if no blue print is left behind inadvertently in case of a partial failure. We conclude that using Con_A-CNT conjugated complex targeting specifically at malign tumor cells is a novel targeted-laser-radiation therapy for tumors in mice.

  16. NatSci 499 E/F: Integrative Scientific Research (iCons 4; 6 credits) Faculty Contact: Prof. Scott M. Auerbach (iCons Program Director; auerbach@chem.umass.edu) or

    E-print Network

    Auerbach, Scott M.

    in self-reflection as learners, providing and utilizing constructive criticism (IE1). Course ComponentsCons Senior Expo. Self-reflection and knowledge integration through portfolio development and dissemination

  17. The rights, tensions, and ideas that inform the con-temporary human experience were explored by the

    E-print Network

    The rights, tensions, and ideas that inform the con- temporary human experience were explored Trustee. Examining the Human Experience ANDREAKANE CLIFFMOORE #12;; and the conception and challenges of human rights from historical, philo- sophical, political, and sociological

  18. Neogene stratigraphic relationships within the Nam Con Son Basin, offshore Vietnam resulting from tectonics, eustasy, and sediment flux 

    E-print Network

    Wright, Christine M.

    2009-05-15

    in the East Nam Con Son Basin. Age constraints were assigned to key stratigraphic horizons by correlating sequence boundaries with published sea level curves. Accommodation in the study area is controlled by shelf -edge compaction, rift-related thermal...

  19. 32 Wesley C. Salmon -it has been appropriate to deny that such appeals to functions involve the con-

    E-print Network

    Fitelson, Branden

    32 Wesley C. Salmon -it has been appropriate to deny that such appeals to functions involve the con's (1962) defense of deductive explanation in her contribution to the third volume #12;34 Wesley C. Salmon

  20. Presentación del estudio “Links” de hombres que tienes sexo con hombres en Buenos Aires, Argentina

    PubMed Central

    Carballo-Diéguez, Alex; Ávila, María M; Balán, Iván C.; Marone, Rubén; Pando, María A.; Barreda, Victoria

    2011-01-01

    Resumen Estudios previos en Buenos Aires reportaron altas prevalencias de HIV entre HSH, con valores que oscilan entre 9 y 14% durante casi 10 años de continuo testeo. El objetivo principal de este estudio fue la evaluación de factores relacionados al comportamiento de alto riesgo para transmisión del HIV entre HSH entre los que se incluyen el conocimiento y factores emocionales, socioculturales y ambientales. Por otro lado se realizó la estimación de prevalencia e incidencia de HIV utilizando RDS (Respondent Driven Sampling), así como la presencia de otras infecciones de transmisión sexual. Por último se evaluaron los hábitos de testeo para HIV indagando que factores facilitan o impiden su realización. El estudio constó de dos fases, en primer lugar una fase cualitativa y posteriormente una fase cuantitativa con una duración total de 4 años y medio. Durante la fase cualitativa se realizaron 44 entrevistas individuales en profundidad, 8 grupos focales y 10 observaciones etnográficas (hoteles, baños públicos (“teteras”), cines pornográficos, fiestas privadas, dark rooms y discotecas). Durante la fase cuantitativa del estudio se realizó el reclutamiento de 500 participantes que provinieron de la Ciudad Autónoma de Buenos Aires, así como del Gran Buenos Aires. El reclutamiento se comenzó con 16 participantes llamados semillas. Se realizó el diagnóstico de infección por HIV, hepatitis B y C (HBV y HCV), Treponema pallidum, Virus Papiloma Humano (HPV) y Chlamidias. La colaboración establecida entre los grupos de trabajo enfocados en áreas diversas posibilitó el abordaje conjunto de nuevas estrategias de investigación antes no exploradas en nuestro país. Los resultados más relevantes de esta investigación serán progresivamente publicados en sucesivos números de Actualizaciones en SIDA. PMID:25264397

  1. 40 CFR 180.1213 - Coniothyrium minitans strain CON/M/91-08; exemption from the requirement of a tolerance.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...false Coniothyrium minitans strain CON/M/91-08; exemption from the requirement...1213 Coniothyrium minitans strain CON/M/91-08; exemption from the requirement...pesticide Coniothyrium minitans strain CON/M/91- 08 when used in or on all food...

  2. PPoollvvoo ddee ccoommppoossiicciinn vvttrreeaa ccoonn aaccttiivviiddaadd bbiioocciiddaa Un grupo de investigacin del CSIC ha desarrollado un polvo vtreo con una alta concentracin

    E-print Network

    forma de Ca2+) como agente biocida. El polvo está compuesto por nanopartículas de óxido de silicio con a ser tóxicas o agresivas con el medio ambiente. Igualmente ocurre con los agentes biocidas orgánicos de calcio (CaO) como agente biocida. La actuación biocida de este polvo vítreo es causada por la

  3. CUERPO CURSO DEPARTAMENTO PERSONA Pdi con vinculacin permanente y pdi doctor -Membres Nats2014-15 SOCIOLOGIA II BAS AMOROS, JOSE ENRIQUE

    E-print Network

    Escolano, Francisco

    CUERPO CURSO DEPARTAMENTO PERSONA Pdi con vinculación permanente y pdi doctor - Membres Nats2014-15 SOCIOLOGIA II BAS AMOROS, JOSE ENRIQUE Pdi con vinculación permanente y pdi doctor - Membres Nats2014-15 SOCIOLOGIA II LA PARRA CASADO, DANIEL Pdi con vinculación permanente y pdi doctor - Membres Nats2014

  4. Con A induction of IgG secretion from a B-lymphoid tumour cell line, A20.

    PubMed Central

    Kim, K J; Dejoy, S Q

    1986-01-01

    We have examined the effect of concanavalin A (Con A), a conventionally known T-cell mitogen, on the induction of Ig secretion from BALB/c B lymphoid cell lines expressing membrane IgM (X16C8.5, BALENTL 17.7.2 and BCL1) or membrane IgG (A20 and M12.4). A20 tumour cells, but not other tumour cells, responded to Con A by secreting Ig as measured by the reverse plaque-forming cell (PFC) assay. Another typical T-cell mitogen, phytohaemagglutinin (PHA), did not have any effect on the differentiation of A20 tumour cells. The addition of NaN3 abolished the PFC formation, showing that IgG PFC formation of A20 tumour cells was due to the active synthesis of secreted IgG and not due to the shedding of mIgG. The increase in the biosynthesis of secreted IgG from A20 tumour cells by Con A was also observed by polyacrylamide gel electrophoresis. The ability of Con A to induce IgG secretion from A20 tumour cells was abolished by the addition of alpha-methylmannoside, confirming that Con A itself, and not some contaminating material in Con A, induced the maturation of A20 tumour cells. Con A was also shown to induce Ig secretion, but not proliferation, in a subset of normal B cells. Thus, we conclude that Con A does give a differentiation signal to a subset of B cells. Images Figure 2 PMID:3530982

  5. Con A induction of IgG secretion from a B-lymphoid tumour cell line, A20.

    PubMed

    Kim, K J; Dejoy, S Q

    1986-09-01

    We have examined the effect of concanavalin A (Con A), a conventionally known T-cell mitogen, on the induction of Ig secretion from BALB/c B lymphoid cell lines expressing membrane IgM (X16C8.5, BALENTL 17.7.2 and BCL1) or membrane IgG (A20 and M12.4). A20 tumour cells, but not other tumour cells, responded to Con A by secreting Ig as measured by the reverse plaque-forming cell (PFC) assay. Another typical T-cell mitogen, phytohaemagglutinin (PHA), did not have any effect on the differentiation of A20 tumour cells. The addition of NaN3 abolished the PFC formation, showing that IgG PFC formation of A20 tumour cells was due to the active synthesis of secreted IgG and not due to the shedding of mIgG. The increase in the biosynthesis of secreted IgG from A20 tumour cells by Con A was also observed by polyacrylamide gel electrophoresis. The ability of Con A to induce IgG secretion from A20 tumour cells was abolished by the addition of alpha-methylmannoside, confirming that Con A itself, and not some contaminating material in Con A, induced the maturation of A20 tumour cells. Con A was also shown to induce Ig secretion, but not proliferation, in a subset of normal B cells. Thus, we conclude that Con A does give a differentiation signal to a subset of B cells. PMID:3530982

  6. Effect of GonaCon™ vaccine on black-tailed prairie dogs: immune response and health effects.

    PubMed

    Yoder, Christi A; Miller, Lowell A

    2010-12-16

    Management of prairie dogs in the past has included poisoning, fumigants, barriers, and relocation. Because of the diverse attitudes related to prairie dog management, nonlethal methods that allow the existence of prairie dogs but help minimize damage related to population growth need to be developed. GonaCon™ is an immunocontraceptive vaccine that elicits antibodies to native GnRH; this prevents the secretion of reproductive hormones necessary for sperm and oocyte production. Prairie dogs were vaccinated with 0.1, 0.2, or 0.4 mL of the GonaCon™ emulsion intramuscularly in the upper thigh containing 100, 200, or 400 ?g GnRH conjugate, respectively. Control animals were vaccinated with 0.4 mL saline emulsion in the upper thigh. Blood samples (?1 mL) were taken from the femoral vein once pretreatment and at 1, 2, 3, 4, 6, and 15 months post-vaccination. Age (adult or juvenile) did not affect immune response to GonaCon™. Antibody titers were higher in the 200 and 400 ?L GonaCon™ groups than in the 100 ?L group, and there was no difference between the 200 and 400 ?L GonaCon™ groups. No adverse effects of GonaCon™ were noted on weight or blood chemistry parameters during the study. GonaCon™ will likely contracept prairie dogs for ?1 year in the field using either 200 or 400 ?g conjugate. GonaCon™ could be incorporated into management plans to help maintain prairie dog populations while reducing habitat degradation due to overpopulation. PMID:21055491

  7. CONFIGURACION EDUROAM PARA MOVILES SYMBIAN S60 v3 Para poder configurar Eduroam en nuestro dispositivo con Symbian primero debemos

    E-print Network

    Valencia, Universidad de

    Trust External CA Root y el (DER) de UTN-USERFirst-Hardware en Jerarquia 1 y le damos a Guardar/Salvar, para cada páginas: #12;Conexión a Eduroam con Symbian S60 v3 PacoEB5HTC Ing. Tec. Teleco. Sistemas Electrónicos. "Ajustes". #12;Conexión a Eduroam con Symbian S60 v3 PacoEB5HTC Ing. Tec. Teleco. Sistemas

  8. Esercizi quarta settimana1 Determinare lo sviluppo asintotico delle seguenti funzioni nella scala delle potenze per x 0 con

    E-print Network

    Marconi, Umberto

    delle potenze per x 0 con almeno tre termini consecutivi: ex - sin x - 1 sinh2 x (1 - cosh x) sin x 3 x + x4 cos sin x sin(1 - cos x) esin x cos x + sin x ex2 Determinare lo sviluppo asintotico delle seguenti funzioni nella scala delle potenze per x + con almeno tre termini consecutivi: 3 x + x4 sinh sin

  9. Perceived pros and cons of smoking and quitting in hard-core smokers: a focus group study

    PubMed Central

    2014-01-01

    Background In the last decade, so-called hard-core smokers have received increasing interest in research literature. For smokers in general, the study of perceived costs and benefits (or ‘pros and cons’) of smoking and quitting is of particular importance in predicting motivation to quit and actual quitting attempts. Therefore, this study aims to gain insight into the perceived pros and cons of smoking and quitting in hard-core smokers. Methods We conducted 11 focus group interviews among current hard-core smokers (n = 32) and former hard-core smokers (n = 31) in the Netherlands. Subsequently, each participant listed his or her main pros and cons in a questionnaire. We used a structural procedure to analyse the data obtained from the group interviews and from the questionnaires. Results Using the qualitative data of both the questionnaires and the transcripts, the perceived pros and cons of smoking and smoking cessation were grouped into 6 main categories: Finance, Health, Intrapersonal Processes, Social Environment, Physical Environment and Food and Weight. Conclusions Although the perceived pros and cons of smoking in hard-core smokers largely mirror the perceived pros and cons of quitting, there are some major differences with respect to weight, social integration, health of children and stress reduction, that should be taken into account in clinical settings and when developing interventions. Based on these findings we propose the ‘Distorted Mirror Hypothesis’. PMID:24548463

  10. Feeding of grey squirrels (Sciurus carolinensis) with the contraceptive agent DiazaCon™: effect on cholesterol, hematology, and blood chemistry.

    PubMed

    Yoder, Christi A; Mayle, Brenda A; Furcolow, Carol A; Cowan, David P; Fagerstone, Kathleen A

    2011-12-01

    Grey squirrels (Sciurus carolinensis) are an invasive species in Britain and Italy. They have replaced native red squirrels (Sciurus vulgaris) throughout most of Britain, and cause damage to trees. Currently, lethal control is used to manage grey squirrel populations in Britain, but nonlethal methods might be more acceptable to the public. One such method is contraception with 20,25-diazacholesterol dihydrochloride (DiazaCon™). DiazaCon™ inhibits the conversion of desmosterol to cholesterol, resulting in increasing desmosterol concentrations and decreasing cholesterol concentrations. Because cholesterol is needed for the synthesis of steroid reproductive hormones, such as progesterone and testosterone, inhibition of cholesterol synthesis indirectly inhibits reproduction. Desmosterol is used as a marker of efficacy in laboratory studies with species that do not reproduce readily in captivity. Grey squirrels were gavaged with a DiazaCon™ solution for 2 days, and then fed DiazaCon™-coated peanuts for an additional 8 days at target doses of 50 and 100 mg DiazaCon™ per kg body weight. There was a significant difference in cholesterol concentrations in the treatment groups compared to the control group. Cholesterol was reduced by ? 40% for 2 months in both treatment groups. There were no differences among groups with respect to blood chemistry and hematology parameters, and mean values are reported. The mean overall dose of DiazaCon™ received was 29.0 ± 1.6 and 55.3 ± 4.3 mg/kg in the low (50 mg/kg) and high dose (100 mg/kg) groups, respectively. DiazaCon™ might provide an effective, acceptable alternative to lethal control. PMID:22182332

  11. Cue-based assertion classification for Swedish clinical text – developing a lexicon for pyConTextSwe

    PubMed Central

    Velupillai, Sumithra; Skeppstedt, Maria; Kvist, Maria; Mowery, Danielle; Chapman, Brian E.; Dalianis, Hercules; Chapman, Wendy W.

    2014-01-01

    Objective The ability of a cue-based system to accurately assert whether a disorder is affirmed, negated, or uncertain is dependent, in part, on its cue lexicon. In this paper, we continue our study of porting an assertion system (pyConTextNLP) from English to Swedish (pyConTextSwe) by creating an optimized assertion lexicon for clinical Swedish. Methods and material We integrated cues from four external lexicons, along with generated inflections and combinations. We used subsets of a clinical corpus in Swedish. We applied four assertion classes (definite existence, probable existence, probable negated existence and definite negated existence) and two binary classes (existence yes/no and uncertainty yes/no) to pyConTextSwe. We compared pyConTextSwe’s performance with and without the added cues on a development set, and improved the lexicon further after an error analysis. On a separate evaluation set, we calculated the system’s final performance. Results Following integration steps, we added 454 cues to pyConTextSwe. The optimized lexicon developed after an error analysis resulted in statistically significant improvements on the development set (83% F-score, overall). The system’s final F-scores on an evaluation set were 81% (overall). For the individual assertion classes, F-score results were 88% (definite existence), 81% (probable existence), 55% (probable negated existence), and 63% (definite negated existence). For the binary classifications existence yes/no and uncertainty yes/no, final system performance was 97%/87% and 78%/86% F-score, respectively. Conclusions We have successfully ported pyConTextNLP to Swedish (pyConTextSwe). We have created an extensive and useful assertion lexicon for Swedish clinical text, which could form a valuable resource for similar studies, and which is publicly available. PMID:24556644

  12. Nest destruction elicits indiscriminate con- versus heterospecific brood parasitism in a captive bird.

    PubMed

    Shaw, Rachael C; Feeney, William E; Hauber, Mark E

    2014-12-01

    Following nest destruction, the laying of physiologically committed eggs (eggs that are ovulated, yolked, and making their way through the oviduct) in the nests of other birds is considered a viable pathway for the evolution of obligate interspecific brood parasitism. While intraspecific brood parasitism in response to nest predation has been experimentally demonstrated, this pathway has yet to be evaluated in an interspecific context. We studied patterns of egg laying following experimental nest destruction in captive zebra finches, Taeniopygia guttata, a frequent intraspecific brood parasite. We found that zebra finches laid physiologically committed eggs indiscriminately between nests containing conspecific eggs and nests containing heterospecific eggs (of Bengalese finches, Lonchura striata vars. domestica), despite the con- and heterospecific eggs differing in both size and coloration. This is the first experimental evidence that nest destruction may provide a pathway for the evolution of interspecific brood parasitism in birds. PMID:25512846

  13. Phase transition and chemical decomposition of shocked CO-N2 mixture.

    PubMed

    Chen, GuanYu; Jiang, XiaoXu; Cheng, XinLu; Zhang, Hong

    2012-08-01

    Using quantum molecular dynamics simulations based on density functional theory including dispersion corrections (DFT-D), we have studied the thermophysical properties of liquid carbon monoxide and nitrogen (CO-N(2)) mixture under extreme conditions. Density functional theory (DFT) method significantly overestimates the pressure as compared to DFT-D. It is demonstrated that the van der Waals (vdW) interaction has a negative contribution to the pressure and tends to reduce the overestimation of the equilibrium volume. We also demonstrate that a negative slope of Hugoniot curve could possibly be caused by both the absorption of dissociation energy and the uncertainties in composition. As density and temperature increase along the Hoguniot curve, the system appears to undergo a continuous transition and provides for a much richer set of dissociation products. The influence of dissociated carbon and oxygen atoms on nitrogen molecules is also discussed. PMID:22894361

  14. The new human papillomavirus (HPV) vaccine: pros and cons for pediatric and adolescent health.

    PubMed

    Thomas, Tami L

    2008-01-01

    The new human papillomavirus (HPV) vaccine is a research breakthrough for pediatric/adolescent health to prevent cervical cancer and related morbidity. The annual heath care cost for the treatment of cervical cancer and genital warts is estimated to be more than three billion dollars a year. The new HPV vaccine has incredible potential to improve reproductive health promotion, reduce health care costs, and close health care disparity gaps. However, issues both for and against the new HPV vaccine, including mandating vaccination, high cost of the vaccine, the short duration of protection offered, and the perceived promotion of sexual activity, cause confusion. Pediatric nurses, including those in advanced practice, benefit by understanding the pros and cons of these issues in advocating for their patients. PMID:19051848

  15. What to consider when regulating electronic cigarettes: Pros, cons and unintended consequences.

    PubMed

    Caponnetto, Pasquale; Saitta, Daniela; Sweanor, David; Polosa, Riccardo

    2015-06-01

    Many public health experts, medical research societies, large health organizations and policy makers have expressed concerns about the increased popularity of electronic cigarettes and have pushed for more restrictive measures ranging from complete bans to tight regulations of these products either as medicines or as tobacco products. But these concerns have never been adequately qualified nor quantified. Without judicious assessment and thorough evaluation, regulations may have unintended consequences that can do more damage than good in public health terms. In this article, we will appraise the existing prominent regulatory frameworks for e-cigarettes, namely, general consumer product, medicinal product and tobacco product regulation, to highlight their pros and cons. Moreover, we provide concrete examples of the unintended consequences which may arise from inappropriate regulatory action. PMID:25857204

  16. A maritime navigation display that provides visual feedback to improve conning officers' ship-handling during low visibility environments.

    PubMed

    Evanoff, Thomas V; Krebs, William K

    2002-12-15

    Navigating a ship at night in close proximity to another vessel is a dangerous task. To improve conning officers' night time ship-handling performance, a visual navigation display is proposed that is mounted on the stern of the aircraft carrier that will help shipboard conning officers manoeuvre in a battle group formation. To test the effectiveness of the visual navigation display, the Nimitz-class aircraft and plane guard vessel, a Ticonderoga-class cruiser, were modelled in a virtual environment. A navigation display condition had significantly fewer navigational positional errors than a non-navigation display condition. The navigation display provided immediate feedback as to whether the aircraft carrier had changed bearing or speed, thus enabling the operator to initiate the appropriate input to maintain station astern of the carrier. Actual or potential applications of this research include the deployment of a maritime navigation display to assist conning officers' ship handling. PMID:12569043

  17. Compito di Comunicazioni radiomobili: 05/04/2005 Si consideri un terminale mobile che si sposta con velocita' v = 50 km/h e che trasmette alla frequenza

    E-print Network

    Abrardo, Andrea

    che si sposta con velocita' v = 50 km/h e che trasmette alla frequenza f0 = 1.5 GHz con bit rate sul deve essere caratterizzato da T = 36, ovvero da K = N - 2T = 183. La velocita' al netto della codifica km/h e che trasmette alla frequenza f0 = 1.5 GHz con bit rate al netto della codifica Rb = 15 kbit

  18. Economic and Ethical Consequences of Natural Hazards in Alpine Valleys (EE-Con)

    NASA Astrophysics Data System (ADS)

    Ortner, Florian; Brantl, Dirk; Meyer, Lukas; Steininger, Karl; Sass, Oliver

    2015-04-01

    The Alps and their population are particularly vulnerable to geomorphological and hydrological hazards and this problem might be amplified by ongoing climate change. Natural disasters cause severe monetary damage which often leads to the difficult question whether it socially pays to protect settlements at high costs or whether alternatively settlement areas should better be abandoned. By investigations in the Johnsbachtal and the Kleinsölktal (Styria), the interdisciplinary project "Economic and Ethical Consequences of Natural Hazards in Alpine Valleys" (EE-Con), funded by the Austrian Academy of Sciences, seeks to answer the following questions: (1) Are natural hazards and associated damages in fact increasing, and is this due to meteorological triggers, to anthropogenic factors or to internal process dynamics? (2) What is the perception and knowledge of local people, how is risk and risk prevention communicated? (3) What is the respective cost ratio between protection infrastructure, soft measures of adaptation and other options (e.g. reduction of settlement area)? (4) What legitimate claims to compensation do people have, how far does societal responsibility go and where does individual responsibility start if parts of the settlement area had to be abandoned? These questions will be tackled in an interdisciplinary cooperation between geography, economics and normative theory (philosophy). EE-Con will follow broadly the path of risk analysis and risk assessment, focusing on the temporal dimension (past - present - future) with the aim to unravel the history of natural hazards in the areas and to analyse the economic values involved. In the following, natural hazard scenarios for the future (2050 and 2100) will be developed considering the economic consequences. Besides this, the project deals with local knowledge, risk perception and risk communication, which will be investigated via group interviews and stakeholder workshops and be integrated into a human-ecological model. Therefore, local people and stakeholders are going to be involved in a transdisciplinary approach from the start of the project. The geographic and economic information will then be used to find proper weighing mechanisms answering the normative questions mentioned above. The questions of enduring the respective costs and of responsibility for protecting the respective entitlements will be investigated from an ethical, a legal, and an economic viewpoint. The overall outcome of the results should provide an integrative view on the economic and ethical consequences of natural hazards in alpine valleys.

  19. BANDO N. 01-2010 PER IL RECLUTAMENTO DI UN RICERCATORE CON RAPPORTO DI LAVORO A TEMPO DETERMINATO

    E-print Network

    Guidoni, Leonardo

    Il Direttore del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" Visto il Regolamento Fisiologia e Farmacologia "Vittorio Erspamer" e la Fondazione "Enrico ed Enrica Sovena", con sede in Roma costituenti chimici"; Vista la Delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio

  20. An E cient Con ict-Resolution Approach to Support Read/Write Operations in a Video Server1

    E-print Network

    Chang, Ye-In

    Mathematics National Chiao Tung University National Sun Yat-Sen University Hsinchu, Taiwan Kaohsiung, Taiwan of subobjects after subobject i are increased by one. Only when such a new con ict occurs, one movement movement cost, a deferring approach is proposed at the cost of an additional bu er. In this approach, n

  1. TECHNOLOGY EVALUATION REPORT: INTERNATIONAL WASTE TECHNOLOGIES/GEO-CON IN SITU STABILIZATION/SOLIDIFICATION - VOLUME III - UPDATE REPORT

    EPA Science Inventory

    The long-term performance tests provide information on the first follow-up sampling and analysis on the SITE program demonstration of the International Waste Technologies additive, and the Geo-Con deep soil mixing equipment. he samples containing PCBs, were collected one year aft...

  2. TECHNOLOGY EVALUATION REPORT: INTERNATIONAL WASTE TECHNOLOGIES/GEO-CON IN SITU STABILIZATION/SOLIDIFICATION - VOLUME IV - UPDATE REPORT

    EPA Science Inventory

    The long-term performance tests provide information on the first follow-up sampling and analysis on the SITE program demonstration of the International Waste Technologies additive, and the Geo-Con deep soil mixing equipment. he samples containing PCBs, were collected one year aft...

  3. FUNDAMENTACIN Body mix es una modalidad del fitness que se ha creado con el fin de unificar

    E-print Network

    Escolano, Francisco

    BODY MIX FUNDAMENTACIÓN Body mix es una modalidad del fitness que se ha creado con el fin de unificar disciplinas como body pump, body balance, body combat y body attack. Vamos a definir brevemente en qué consiste cada una de las disciplinas: Body pump es un programa de entrenamiento que destaca por

  4. 2Un Sobrevuelo del Asteroide Lutetia La nave espacial europea Rosetta de la Agencia, con instrumentos de la

    E-print Network

    Christian, Eric

    instrumentos de la NASA a bordo, sobrevoló el asteroide Lutetia sábado, 10 de julio 2010. El diámetro del2Un Sobrevuelo del Asteroide Lutetia La nave espacial europea Rosetta de la Agencia, con asteroide es de unos 130 km. Esta fotografía fue tomada desde una distancia de 3.162 kilometros. Problema 1

  5. Adding Photos Lightbox GalleryCon nued 1 .Toad d im agestoM ood le,inyourtexted itor,

    E-print Network

    Selmic, Sandra

    Adding Photos Lightbox GalleryCon nued 1 .Toad d im agestoM ood le,inyourtexted itor, locate,create a com pressed fold er (.z ip) w ithallthe im agesyou w ould like toad d to the Lightbox Gallery. 2.W

  6. PESCA ARTESANAL DE BIVALVOS (Anadara tuberculosa y A. similis) Y SU RELACIÓN CON EVENTOS AMBIENTALES. PACÍFICO COLOMBIANO

    Microsoft Academic Search

    Carlos A. Borda; Raúl Cruz

    RESUMEN La piangua (Anadara tuberculosa y Anadara similis) habita en las zonas mesolitorales asociado a las raíces del mangle (Rhizophora spp.). En Colombia, estos bivalvos son la base de una pesquería exclusivamente artesanal de subsistencia, desarrollada por las comunidades ubicadas en el litoral del Océano Pacífico, cuya población es de 70 000 habitantes, 18 000 están relacionados con la actividad

  7. DiSTiL is a software generator that implements a declarative domain-specific language (DSL) for con-

    E-print Network

    Smaragdakis, Yannis

    Abstract DiSTiL is a software generator that implements a declarative domain-specific language (DSL) for con- tainer data structures. DiSTiL is a representative of a new approach to domain-specific language implementa- tion. Instead of being the usual one-of-a-kind stand- alone compiler, DiSTiL is an extension

  8. ¿Coinciden EVA(R) y Utilidad Economica (UE) con los metodos de Flujo de Caja Descontado en valoracion de empresas?

    Microsoft Academic Search

    Ignacio Vélez Pareja; Joseph Tham

    2003-01-01

    En Vélez-Pareja y Tham (2001), presentamos diferentes maneras de valorar los flujos de caja. Primero se utilizó el costo promedio ponderado de capital (CPPC) (Weighted Average Cost of Capital, WACC) para descontar el flujo de caja libre (FCL). Segundo, se descontó el FCL con el WACC ajustado. Y en tercer lugar descontamos el flujo de caja del capital (capital cash

  9. HumanWildlife Interactions 6(2):327334, Fall 2012 Mixed-breed guarding dogs reduce con-

    E-print Network

    Human­Wildlife Interactions 6(2):327­334, Fall 2012 Mixed-breed guarding dogs reduce con- flict the use of local, medium- sized, mixed-breed guarding dogs to reduce predation and retaliatory killing was attributed to cougars (Puma concolor) and culpeos (Lycalopex culpaeus). All herders with dogs that reached

  10. Un Sistema de Apoyo al Consenso Adaptativo para Problemas de Toma de Decisin en Grupo con Informacin Heterognea

    E-print Network

    Granada, Universidad de

    hacia el nivel de acuerdo buscado, TOMA DE DECISIONES EN GRUPO GRUPO DE EXPERTOS MODERADOR PREFERENCIAS CONSENSUADAS Toma de Decisiones I: Modelos 157 #12;Figura 3. El proceso de unificación deUn Sistema de Apoyo al Consenso Adaptativo para Problemas de Toma de Decisión en Grupo con

  11. Oxacilin-resistant Coagulase-negative staphylococci (CoNS) bacteremia in a general hospital at São Paulo city, Brasil.

    PubMed

    d'Azevedo, P A; Secchi, C; Antunes, A L S; Sales, T; Silva, F M; Tranchesi, R; Pignatari, A C C

    2008-10-01

    In the last decades, coagulase-negative staphylococci (CoNS), especially Staphylococcus epidermidis have become an important cause of bloodstream infections. In addition, rates of methicillin-resistance among CoNS have increased substantially, leading to the use of glicopeptides for therapy. The objective of this study was to evaluate eleven consecutives clinically relevant cases of oxacillin-resistant CoNS bacteremia in a general hospital localized in São Paulo city, Brazil. Five different species were identified by different phenotypic methods, including S. epidermidis (5), S. haemolyticus (3), S. hominis (1), S. warneri (1) and S. cohnii subsp urealyticus (1). A variety of Pulsed Field Gel Electrophoresis profiles was observed by macrorestriction DNA analysis in S. epidermidis isolates, but two of three S. haemolyticus isolates presented the same profile. These data indicated the heterogeneity of the CoNS isolates, suggesting that horizontal dissemination of these microorganisms in the investigated hospital was not frequent. One S. epidermidis and one S. haemolyticus isolates were resistant to teicoplanin and susceptible to vancomycin. The selective pressure due to the use of teicoplanin in this hospital is relevant. PMID:24031279

  12. MATH 220: CONVERGENCE OF THE FOURIER SERIES We now discuss convergence of the Fourier series on compact intervals I. `Con-

    E-print Network

    Vasy, András

    MATH 220: CONVERGENCE OF THE FOURIER SERIES We now discuss convergence of the Fourier series on compact intervals I. `Con- vergence' depends on the notion of convergence we use, such as (i) L2 : uj u(x) - u(x)| 0. Note that pointwise convergence is too weak for most purposes, so e.g. just because uj u

  13. Asunto : OFERTA DE CURSOS DE INGLS DE VERANO PARA CHICOS DE 4 A 18 AOS CON DESCUENTOS EXCLUSIVOS

    E-print Network

    Oro, Daniel

    Asunto : OFERTA DE CURSOS DE INGLÉS DE VERANO PARA CHICOS DE 4 A 18 AÑOS CON DESCUENTOS EXCLUSIVOS a chicos de 4 a 18 años, las propuestas más originales en sus cursos residenciales de inglés y deportes durante el verano. Estos intensivos programas lingüísticos, únicos en Europa, son cursos residenciales y

  14. CALL FOR PAPERS CLimAtE ECOnOmiCS And LAw COnFEREnCE

    E-print Network

    Mühlemann, Oliver

    CALL FOR PAPERS CLimAtE ECOnOmiCS And LAw COnFEREnCE ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ Climate Economics and Law Conference 16 ­ 17 June 2011 University of Bern, Bern, Switzerland ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ The NCCR Climate invites scientists to the "Climate Economics and Law Conference" that will take place

  15. Low energy consumption is becoming the primary design con-sideration for battery-operated and portable embedded sys-

    E-print Network

    Childers, Bruce

    Abstract Low energy consumption is becoming the primary design con- sideration for battery-operated in 2000 [21]. Not only has the sheer demand for battery-operated devices grown, but the expectations, battery operated embedded systems, such as cellular phones, digital motion and still cameras, personal

  16. Estimado Colega, Es un deseo de muchos de nosotros en Colombia el de poder contar con un Instituto

    E-print Network

    Uribe, Bernardo

    Estimado Colega, Es un deseo de muchos de nosotros en Colombia el de poder contar con un Instituto creación de un Instituto de Matemáticas en Colombia ha existido desde hace varios años. Son muchos los miembros de la comunidad matemática del país y del extranjero que consideran que Colombia ha alcanzado el

  17. 1. Introduction In a uid con ned to a plane layer and heated from below, convection can

    E-print Network

    Rucklidge, Alastair

    1. Introduction In a uid con#12;ned to a plane layer and heated from below, convection can occur of convective behaviour loses stability to another. This paper is concerned with the analysis of the temporal behaviour of two-dimensional double convection: roll convection in the presence of a stabilizing solute

  18. Data Structures with Dynamical Random Transitions Nadine Guillotin-Plantard Bruno Pin con y Ren e Schott z

    E-print Network

    Henri Poincaré -Nancy-Université, Université

    Data Structures with Dynamical Random Transitions Nadine Guillotin-Plantard #3; Bruno Pin#24;con y Ren#19;e Schott z Key words: Dynamic random walks, data structures, dynamical systems, large deviation-standard) probabilistic analysis of dynamic data structures whose sizes are considered as dynamic random walks. The basic

  19. Global trade in dairy products involves complex and con-tentious issues. Viewed broadly from the perspective of

    E-print Network

    Radeloff, Volker C.

    Global trade in dairy products involves complex and con- tentious issues. Viewed broadly from the perspective of "society," there are large benefits from liberalizing trade. Viewed narrowly from the perspective of dairy producers, liberalized trade is desirable only if it expands exports and reduces imports

  20. Connessione di R Nota. Se c R, con la frase intervallo di centro c intendiamo intervallo di centro c e

    E-print Network

    Marconi, Umberto

    1 Connessione di R Nota. Se c R, con la frase intervallo di centro c intendiamo intervallo di centro c e raggio un numero reale maggiore di 0. La seguente proposizione `e stata dimostrata a lezione ed `e analoga a [GDM, 6.3.1]. Essa dice che un insieme A `e aperto se e solo se per ogni c A esiste

  1. Deutsche Bank Deutsche Bank S.p.A. la consociata italiana di Deutsche Bank AG che, con oltre

    E-print Network

    Robbiano, Lorenzo

    Deutsche Bank Deutsche Bank S.p.A. è la consociata italiana di Deutsche Bank AG che, con oltre 100.000 collaboratori in più di 72 Paesi nel mondo, vanta più di 24 milioni di clienti. Deutsche Bank ricerca brillanti

  2. A new millimeter-wave observation of the weakly bound CO-N2 complex

    NASA Astrophysics Data System (ADS)

    Surin, L. A.; Potapov, A.; Müller, H. S. P.; Schlemmer, S.

    2015-01-01

    New millimeter-wave transitions of the CO-N2 van der Waals complex have been observed using the intracavity OROTRON jet spectrometer in the frequency range of 103-159 GHz. For the less abundant form, CO-paraN2, a total of 37 rotational transitions were assigned to three K = 0-0, 0-1, 2-1 subbands connecting the (jCO, jN2) = (1, 1) and (jCO, jN2) = (0, 1) internal rotor states. The upper K = 0 and K = 2 "stacks" of rotational levels were probed for the first time here by millimeter-wave spectroscopy following a recent infrared study by Rezaei et al. (2013). The observation of new subbands fixes with higher precision not only these upper K = 0 and K = 2 but also lower K = 1(f) levels, not linked with other stacks in earlier rotational studies. For the more abundant form, CO-orthoN2, five new P-branch rotational transitions of the K = 0-0 "CO bending" subband are reported, thus extending previous measurements. Nuclear quadrupole hyperfine structure due to the presence of two equivalent 14N nuclei was partly resolved and analyzed to give additional information about the angular orientation of the N2 molecule in the complex.

  3. [Emission spectrum of liquid CO-N2 mixture at shock compression].

    PubMed

    Sun, Yue; Yi, Peng-Fei; Chen, Xian-Meng; Liu, Fu-Sheng; Zhang, Ming-Jian; Zheng, Xue-Ping; Xue, Xue-Dong

    2009-04-01

    Driving a copper projectile to impact a cryo-target made of aluminous alloy at the speed of 2.21 km x s(-1) with a two stage light gas gun, a proper one dimensional shockwave with a speed of 18.76 km x s(-1) was generated and directly acted on a uniform liquid in target, which was condensed by proportional gaseous carbon monoxide and nitrogen. At the measurement of Hugoniots, the full linear spectrum entirely dissociated with the plasma under the shock pressure of 33.5 GPa was caught by the use of intensified charge coupled device and accurate spectrographic technology. From the analysis of the spectrum, the authors know that the transient spectrograph with six channels can be used to measure and record the course of shock compression-irradiancy reliably, and the emitted spectral lines of shock compressed products indicated that the thermal dissociation and phase transition had occurred in homogeneous liquid of CO-N2. Furthermore, comparing the spectral intensity of lower central wavelength with that of higher, the fact of stronger intensity of 488 nm also validates that changes from "optic thin" to "optic thick" exist indeed in dense hydrocarbon liquid acted on by shock pressure. PMID:19626860

  4. Chemically triggered C-ON bond homolysis in alkoxyamines: regioselectivity and chemoselectivity.

    PubMed

    Audran, Gérard; Brémond, Paul; Ibanou, Matisse Bim Batsiandzy; Marque, Sylvain R A; Roubaud, Valérie; Siri, Didier

    2013-11-28

    Recently, we examplified the activation of the C-ON bond homolysis by protonation, alkylation, benzylation, acylation, oxidation and complexation with a Lewis acid of the nitrogen atom of the 1-(pyridin-4-yl)ethyl fragment (Chem. Commun., 2011, 4291 and Org. Lett., 2012, 358) and of the 1-(pyridin-2-yl)ethyl fragment (J. Org. Chem. ASAP Doi:10.1021/jo401674v) of (N-(2-methylpropyl)-N-(1-diethylphosphono-2,2-dimethylpropyl)-N-oxyl) SG1-based alkoxyamines. The quaternization of the 1-(pyridin-3-yl)ethyl fragment by the aforementioned reactions was investigated for the corresponding SG1-based alkoxyamines. In sharp contrast to the quaternization at ortho and para positions of the pyridyl moiety, the effect of the quaternization at the meta position was weak. The effects of quaternization at ortho, meta and para positions were investigated through natural bond orbital and Mulliken charges, HOMO-LUMO interactions in the starting materials and the radical stabilization energy of the released 1-puridylmethyl radicals using DFT calculations with the B3LYP/6-31G(d) and UBMK/6-311+G(3df,2p)//R(O)B3LYP/6-31G(d) methods, respectively. PMID:24114038

  5. Vibrational relaxation of CO(n = 1) in collisions with He

    SciTech Connect

    Schinke, R.; Diercksen, G.H.F.

    1985-11-01

    We present a full ab initio study of vibrational relaxation of CO(n = 1) in collisions with /sup 3/He and /sup 4/He. The vibrational coordinate dependence of the interaction potential is calculated directly. Dynamical calculations are performed within the IOS and the CS approximation. The IOS cross sections agree very well with the corresponding CS results for both He isotopes, however, the ratio IOS/CS shows a different energy behavior for /sup 3/He and /sup 4/He, respectively. The CS rates for /sup 3/He agree extremely well with the experimental relaxation rates. Although only the reduced mass is changed for /sup 4/He the agreement with experiment is less favorable in this case. It is explicitly demonstrated that the often used procedure to extract the vibrational coordinate dependence of the interaction potential from a dumbbell fit of the rigid-rotor surface is wrong for He--CO. For /sup 3/He the corresponding cross sections are 3--10 times smaller than those obtained form the ab initio potential although the vibrationally elastic parts of the interaction potential are identical.

  6. Strain Rate into South American Plate by SIRGAS-CON Geodetic Observations

    NASA Astrophysics Data System (ADS)

    Marotta, G. S.; Franca, G. S.; Monico, J. G.; Fuck, R. A.

    2013-05-01

    In this study were investigated the surface strain rates computed from the direction variations and velocity values estimated from the coordinates of the continuous monitoring geodetic network called SIRGAS-CON. That investigation was done using points located in the South American plate. The determination of the strain rate was based on the Finite Element method using points defined by Delaunay triangulation (sub-networks). Each one of sub-networks was considered as an homogeneous solid body. Using these methods was possible to separate the strain from the plate movement. The results showed that there are differences of strain rate along the South American plate. From the results were suggest that near to the west board of the plate, the strain is more significant, as expected, because this region is near to one area where Nazca Plate subduct South American Plate. It was detected that the contraction region founded in this area coincides whit the region where occurs most of earthquakes of greater magnitude. Far from the board, there are some areas with anomalies of significant strain of extension and contraction that can be originated by differences of stress aligned with different geological composites. By the results, It may be concluded that large surface movements occur in regions with more heterogeneous geological structures and multiple event of rupture, that large earthquakes arising from large tectonic activity into South American Plate are concentrated in areas with contraction strain rates predominantly oriented towards northeast-southwest, that significant amounts of elastic strain can be accumulated over geological structures away from fault plate boundary and that the behavior of contractions and extensions are similar to that found by different researches involving geophysical studies. Dilation and principal components of strain rate

  7. Strain Rate by Geodetic Observations Associated with Seismic Events in the SIRGAS-CON Network Region.

    NASA Astrophysics Data System (ADS)

    Marotta, G. S.; Franca, G.; Galera Monico, J. F.; Fuck, R. A.

    2014-12-01

    This research investigates surface strains related to seismic events and their relationship with pre- and post-seismic events in South American, Antarctica, Nazca, Cocos, North American and Caribbean plates , by analyzing the variation of estimated earth coordinates, for the period 2000-2014, supplied by a geodetic network called SIRGAS-CON. Based on data provided by the USGS for the same period, and after the Global Congruency test, we selected the events associated with unstable geodetic network points. The resulting strains were estimated based on the finite element method. It was possible to determine the strains along with the resulting guidelines for pre- and post-seismic, considering each region formed for analysis as a homogeneous solid body. Later, a multi-year solution of the network was estimated and used to estimate the strain rates of the earth surface from the changing directions of the velocity vectors of 332 geodetic points located in the South American plate and surround plates. The strain rate was determined and, using Euler vector computed, it was possible to estimate the convergence and accommodation rates to each plate. The results showed that contraction regions coincide with locations with most of the high magnitude seismic events. It suggest that major movements detected on the surface occur in regions with more heterogeneous geological structures and multiple rupture events; significant amounts of elastic strain can be accumulated on geological structures away from the plate boundary faults; and, behavior of contractions and extensions is similar to what has been found in seismological studies. Despite the association between seismic events and the strain of geodetic network, some events of high magnitude were excluded because it does not show the surface strain, which is located at great depths. It was confirmed that events of greater magnitude provide increased surface strain rate when compared with other similar depths.

  8. Characterization Data Package for Containerized Sludge Samples Collected from Engineered Container SCS-CON-210

    SciTech Connect

    Fountain, Matthew S.; Fiskum, Sandra K.; Baldwin, David L.; Daniel, Richard C.; Bos, Stanley J.; Burns, Carolyn A.; Carlson, Clark D.; Coffey, Deborah S.; Delegard, Calvin H.; Edwards, Matthew K.; Greenwood, Lawrence R.; Neiner, Doinita; Oliver, Brian M.; Pool, Karl N.; Schmidt, Andrew J.; Shimskey, Rick W.; Sinkov, Sergey I.; Snow, Lanee A.; Soderquist, Chuck Z.; Thompson, Christopher J.; Trang-Le, Truc LT; Urie, Michael W.

    2013-09-10

    This data package contains the K Basin sludge characterization results obtained by Pacific Northwest National Laboratory during processing and analysis of four sludge core samples collected from Engineered Container SCS-CON-210 in 2010 as requested by CH2M Hill Plateau Remediation Company. Sample processing requirements, analytes of interest, detection limits, and quality control sample requirements are defined in the KBC-33786, Rev. 2. The core processing scope included reconstitution of a sludge core sample distributed among four to six 4-L polypropylene bottles into a single container. The reconstituted core sample was then mixed and subsampled to support a variety of characterization activities. Additional core sludge subsamples were combined to prepare a container composite. The container composite was fractionated by wet sieving through a 2,000 micron mesh and a 500-micron mesh sieve. Each sieve fraction was sampled to support a suite of analyses. The core composite analysis scope included density determination, radioisotope analysis, and metals analysis, including the Waste Isolation Pilot Plant Hazardous Waste Facility Permit metals (with the exception of mercury). The container composite analysis included most of the core composite analysis scope plus particle size distribution, particle density, rheology, and crystalline phase identification. A summary of the received samples, core sample reconstitution and subsampling activities, container composite preparation and subsampling activities, physical properties, and analytical results are presented. Supporting data and documentation are provided in the appendices. There were no cases of sample or data loss and all of the available samples and data are reported as required by the Quality Assurance Project Plan/Sampling and Analysis Plan.

  9. CORSI DI STUDIO AD ACCESSO CON VERIFICA DEI SAPERI MINIMI A.A. 2013-2014 CORSO DI LAUREA IN SCIENZE DELLA COMUNICAZIONE

    E-print Network

    Romeo, Alessandro

    CORSI DI STUDIO AD ACCESSO CON VERIFICA DEI SAPERI MINIMI A.A. 2013-2014 CORSO DI LAUREA IN SCIENZE a ripetere la prova. #12;CORSI DI STUDIO AD ACCESSO CON VERIFICA DEI SAPERI MINIMI A.A. 2013-2014 CORSO DI

  10. Si te gusta la msica y deseas formar parte de una orquesta de formacin, no dejes pasar la oportunidad de disfrutar con msicos de diferentes nacio-

    E-print Network

    Escolano, Francisco

    ) y no superar los 35 años de edad - Residir en la Comunidad Valenciana. CRITERIOS DE SELECCIÓN - Ser en mi menor. I Mov.: desde la letra H hasta la K. II Mov.: desde la letra B hasta Moderato con anima ­ Sinfonía No. 5 Op. 64 en mi menor. I Mov.: desde la letra H hasta la K. III Mov.: desde la letra E (con

  11. Applying New Technologies: ANT Automation es una empresa de Automatizacin Industrial, con operaciones en USA, Argentina y Espaa. La empresa est conformada por un slido grupo de

    E-print Network

    Maguitman, Ana Gabriela

    Applying New Technologies: ANT Automation es una empresa de Automatización Industrial, con más de 12 años de experiencia en Software/Automatización Industrial y por nuevos jóvenes talentos con el desarrollo de productos de software industrial: OPC, SCADA, MES, VISION ARTIFICIAL, MODELOS

  12. Corso di Teoria dei Gruppi -a.a. 2009-2010 Sia G un gruppo abeliano. Indichiamo con G l'insieme degli omomorfismi G C, dove C

    E-print Network

    Cornalba, Maurizio

    Corso di Teoria dei Gruppi - a.a. 2009-2010 Esercizi 3 Sia G un gruppo abeliano. Indichiamo con G l'insieme degli omomorfismi G CÃ?, dove CÃ? `e il gruppo moltiplicativo dei numeri complessi non nulli. Se , sono elementi di G, poniamo (g) = (g)(g) per ogni g G. 1. Mostrare che G. 2. Mostrare che con il prodotto

  13. Storm impacts along European coastlines. Part 1: The joint effort of the MICORE and ConHaz Projects

    Microsoft Academic Search

    Paolo Ciavola; Oscar Ferreira; Piet Haerens; Mark Van Koningsveld; Clara Armaroli; Quentin Lequeux

    2011-01-01

    The current paper discusses the topic of marine storm impact along European coastlines, presenting results from two FP7 Projects currently focusing on this topic, one working on the physical aspects of the problem (MICORE) and the other one on the socio-economic implications (ConHaz).The MICORE Project aims to provide on-line predictions of storm-related physical hazards (hydrodynamic as well as morphodynamic). The

  14. PHA and con A-induced chemiluminescence of human blood mononuclear cells and granulocytes in luminol or lucigenin

    Microsoft Academic Search

    Katalin Merétey; Mariann Antal; Z. Rozsnyay; Ute Böhm; Erzsébet Elekes; Gy. Genti

    1987-01-01

    Phytohemagglutinin (PHA) and concanavaiin A (Con A) can evoke a chemiluminescence (CL) response both in granulocytes and blood mononuclear cells. We have used two parallel systems to compare the quantity and quality of oxygen radicals produced during activation. While the luminol-enhanced CL response is linked to the myeloperoxidase-H2O2-chloride system, the lucigenin-dependent light production measures only the Superoxide radical. PHA produced

  15. Timing and Tectonic implications of basin inversion in the Nam Con Son Basin and adjacent areas, southern South China Sea 

    E-print Network

    Olson, Christopher Charles

    2001-01-01

    illustrating the deformed Mesozoic forearc basin sediments shown in Figures 37 B-D. 102 37B Profile "A" correlates to the northern extension of the Natuna Arch basement high between the Eastern and Western Nam Con Son sub...-basins . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ?. .. . . . . . . . . . . . , . . . . , . . . . . . . . . . . . 103 37C Seismic profile "B" crosses the Natuna Arch south of profile "A" . . . 37D Deformed Mesozoic forearc basin fill south of seismic profiles "A" and "B" 105 38 Eastern margin of the Natuna Arch heading into the East Natuna Basin...

  16. EFFETTO DELL'ORIENTAMENTO DELLE FIBRE SULLA RESISTENZA A FATICA DI UNA POLIAMMIDE 6 RINFORZATA CON FIBRE DI VETRO

    Microsoft Academic Search

    A. Bernasconi; P. Davoli; A. Basile; A. Filippi

    Sommario In questo lavoro vengono presentati i risultati dello studio dell'effetto dell'orientamento delle fibre sulla resistenza a fatica di una poliammide 6. sono state eseguite prove di fatica su provini estratti da lastre ottenute per stampaggio ad iniezione. I provini sino stati ritagliati con diversi orientamenti rispetto all'asse della lastra, in modo da ottenere differenti orientamenti delle fibre di rinforzo

  17. Investigación e innovación en el campo de la vivienda social. Una experiencia desde la investigación en articulación con la docencia

    Microsoft Academic Search

    Gastón Badillos; Roberto Kuri; Horacio Bertuzzi; Fernando Lario

    2007-01-01

    La vivienda con su especialización espacial y constructiva, tal como masivamente se sigue produciendo hoy, no parece ser ya un soporte apto para los múltiples programas que en ella se desarrollan y que cambian en tiempos relativamente cortos.\\u000a\\u000aNo podemos concebir la vivienda como un hecho cerrado sino como un sistema abierto y vivo (evolutivo y adaptable).\\u000a\\u000aEste trabajo reseña

  18. ConReg-R: Extrapolative recalibration of the empirical distribution of p-values to improve false discovery rate estimates

    PubMed Central

    2011-01-01

    Background False discovery rate (FDR) control is commonly accepted as the most appropriate error control in multiple hypothesis testing problems. The accuracy of FDR estimation depends on the accuracy of the estimation of p-values from each test and validity of the underlying assumptions of the distribution. However, in many practical testing problems such as in genomics, the p-values could be under-estimated or over-estimated for many known or unknown reasons. Consequently, FDR estimation would then be influenced and lose its veracity. Results We propose a new extrapolative method called Constrained Regression Recalibration (ConReg-R) to recalibrate the empirical p-values by modeling their distribution to improve the FDR estimates. Our ConReg-R method is based on the observation that accurately estimated p-values from true null hypotheses follow uniform distribution and the observed distribution of p-values is indeed a mixture of distributions of p-values from true null hypotheses and true alternative hypotheses. Hence, ConReg-R recalibrates the observed p-values so that they exhibit the properties of an ideal empirical p-value distribution. The proportion of true null hypotheses (?0) and FDR are estimated after the recalibration. Conclusions ConReg-R provides an efficient way to improve the FDR estimates. It only requires the p-values from the tests and avoids permutation of the original test data. We demonstrate that the proposed method significantly improves FDR estimation on several gene expression datasets obtained from microarray and RNA-seq experiments. Reviewers The manuscript was reviewed by Prof. Vladimir Kuznetsov, Prof. Philippe Broet, and Prof. Hongfang Liu (nominated by Prof. Yuriy Gusev). PMID:21595983

  19. Deformation sequences of the Day Nui Con Voi metamorphic belt, northern Vietnam

    NASA Astrophysics Data System (ADS)

    Yeh, M. W.; Lee, T. Y.; Lo, C. H.; Chung, S. L.; Lan, C. Y.; Lee, J. C.; Lin, T. S.; Lin, Y. J.

    2003-04-01

    The correlation of structure, microstructure and metamorphic assemblages is of fundamental importance to the understanding of the complex tectonic history and kinematics of the Day Nui Con Voi (DNCV) metamorphic belt in Vietnam along the Ailao Shan-Red River (ASRR) shear zone as it provides constraints on the relative timing of the deformation, kinematics and metamorphism. High-grade metamorphic rocks of amphibolite faces showed consistent deformation sequences of three folding events followed by one brittle deformation through all four cross sections from Lao Cai to Viet Tri indicated the DNCV belt experienced similar deformation condition throughout its length. The first deformation event, D1, produced up-right folds (locally preserved) with sub-vertical, NE-SW striking axial planes with dextral sense of shear probably formed during the early phase of the lowermost Triassic Indosinian orogeny. Followed by this compressional event is a gravitational collapsing event, D2, which is the major deformation and metamorphic event characterized by kyanite grade metamorphism and large scale horizontal folds with NW-SE (320) striking sub-horizontal axial pane showing sinsistral sense of shear most likely formed during the Oligocene-Miocene SE extrusion of Indochina peninsula. The 3rd folding event, D3, is a post-metamorphism doming event with NW-SE (310) striking sub-vertical axial plane that folded/tilted the once sub-horizontal D2 axial planes into shallowly (<30 degrees) NE dipping on the NE limb, and SW dipping on the SW limb possibly due to left-lateral movement of the N-S trending Xian Shui He fault system in Mid-Miocene. The outward decreasing of the metamorphic grade from kyanite to garnet then biotite indicated the D3 occurred post metamorphism. Reactivation of the sub-horizontal D2 fold axial planes showed dextral sense of shear possibly due to Late Miocene-Pliocene right-lateral movement of the ASRR shear zone. This right lateral movement continuously deformed the DNCV with brittle fractures such as joints and normal faults (D4) striking NE-SW to E-W and NW-SE.

  20. CHILES Con Pol: Probing galaxy evolution, the dark Universe, and cosmic magnetism with a deep 1000 hour Jansky VLA survey

    NASA Astrophysics Data System (ADS)

    Hales, Christopher A.; Chiles Con Pol Collaboration

    2014-04-01

    We recently started a 1000 hour campaign to observe 0.2 square degrees of the COSMOS field in full polarization continuum at 1.4 GHz with the Jansky VLA, as part of a joint program with the spectral line COSMOS HI Large Extragalactic Survey (CHILES). When complete, we expect our CHILES Continuum Polarization (CHILES Con Pol) survey to reach an unprecedented SKA-era sensitivity of 0.7 uJy per 4 arcsecond FWHM beam. Here we present the key goals of CHILES Con Pol, which are to (i) produce a source catalog of legacy value to the astronomical community, (ii) measure differential source counts in total intensity, linear polarization, and circular polarization in order to constrain the redshift and luminosity distributions of source populations, (iii) perform a novel weak lensing study using radio polarization as an indicator of intrinsic alignment to better study dark energy and dark matter, and (iv) probe the unknown origin of cosmic magnetism by measuring the strength and structure of intergalactic magnetic fields in the filaments of large scale structure. The CHILES Con Pol source catalog will be a useful resource for upcoming wide-field surveys by acting as a training set for machine learning algorithms, which can then be used to identify and classify radio sources in regions lacking deep multiwavelength coverage.

  1. Water as an economic good and water tariff design. Comparison between IBT-con and IRT-cap

    NASA Astrophysics Data System (ADS)

    Liu, Junguo; Savenije, Hubert H. G.; Xu, Jianxin

    Although the proclamation of “water as an economic good” has been generally accepted among water resources managers, there are still some debates on the explanation of this topic. In this paper it is argued that different water forms or uses have different kinds of economic value. Even for the same form or use, water economic value can be transferred from one kind to another by interventions. If water is an economic good, water pricing should be recognized as one of the important incentive measures for water demand management. Although the increased block tariffs (IBTs) have become the tariff structure of choice in many developing countries, it still deserves more careful examination. The traditional IBT-con cannot achieve the initial objectives of IBTs for its incorrect designed structure. This paper is intent to critically examine the use of IBT-con and to strongly promote a new tariff structure, IRT-cap. The case study of Weinan City shows that IRT-cap is an effective tariff to achieve the objectives of equity, simplicity, transparency and implement as well. Also IRT-cap seems easier to achieve cost recovery than the traditional IBT-con taking the ability to pay of water consumers into account. Pilot projects are necessary to be formulated for verification of this new tariff.

  2. Clinico-Pathological Caracteristics, Therapeutic Features and Post-operative Course of Colorectal Cancer in Elderly Patients

    PubMed Central

    Bouassida, Mahdi; Chtourou, Mohamed Fadhel; Hamzaoui, Lamine; Sassi, Selim; Mighri, Mohamed Mongi; Azzouz, Mohamed M’Saddak; Touinsi, Hassen; Sassi, Sadok

    2014-01-01

    Statement of Problem: Colorectal cancer is predominantly a disease of elderly people and is a major cause of morbidity and mortality in the elderly population. The geriatric colorectal population is a very heterogeneous group, including patients with excellent health status and others with comorbid conditions, functional dependency, and limited life expectancy. On the other hand, the effectiveness of surgery for colorectal cancer depends on it being carried out safely, which allows most patients to return to productive lives, with an improved post-operative life expectancy or at least one that is not diminished by the surgery. Materials and Methods: This work is a descriptive study of a retrospective cohort, based on administrative databases, of all patients with colorectal cancer diagnosed or treated in our institution. We extracted data on sociodemographic characteristics, comorbidity, type of cancer, stage of cancer, type of treatment received, post-operative complications and cause of post-operative death. We compared differences between an elderly group (Group A) (age >75 years) and a group of patients below 75 years (Group B). Results: We found that elderly patients with colorectal cancer were more likely to be operated in emergent conditions, had more non-specific complications and more post-operative mortality than patients below 75 years. On the other hand, tumours stages, tumours characteristics and post-operative specific morbidity have been proved to be similar, both in Group A and Group B patients. Conclusion: These results suggest that surgery is feasible and can be safe for patients above 75 years, but it needs much more evaluation of comorbidities, pre- and post-operative intensive care to avoid post-operative non-specific complications. PMID:24596729

  3. Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors

    PubMed Central

    2013-01-01

    Background Aberrant DNA methylation of regulatory genes has frequently been found in human breast cancers and correlated to clinical outcome. In the present study we investigate stage specific changes in the DNA methylation patterns in order to identify valuable markers to understand how these changes affect breast cancer progression. Methods Quantitative DNA methylation analyses of 12 candidate genes ABCB1, BRCCA1, CDKN2A, ESR1, GSTP1, IGF2, MGMT, HMLH1, PPP2R2B, PTEN, RASSF1A and FOXC1 was performed by pyrosequencing a series of 238 breast cancer tissue samples from DCIS to invasive tumors stage I to IV. Results Significant differences in methylation levels between the DCIS and invasive stage II tumors were observed for six genes RASSF1A, CDKN2A, MGMT, ABCB1, GSTP1 and FOXC1. RASSF1A, ABCB1 and GSTP1 showed significantly higher methylation levels in late stage compared to the early stage breast carcinoma. Z-score analysis revealed significantly lower methylation levels in DCIS and stage I tumors compared with stage II, III and IV tumors. Methylation levels of PTEN, PPP2R2B, FOXC1, ABCB1 and BRCA1 were lower in tumors harboring TP53 mutations then in tumors with wild type TP53. Z-score analysis showed that TP53 mutated tumors had significantly lower overall methylation levels compared to tumors with wild type TP53. Methylation levels of RASSF1A, PPP2R2B, GSTP1 and FOXC1 were higher in ER positive vs. ER negative tumors and methylation levels of PTEN and CDKN2A were higher in HER2 positive vs. HER2 negative tumors. Z-score analysis also showed that HER2 positive tumors had significantly higher z-scores of methylation compared to the HER2 negative tumors. Univariate survival analysis identifies methylation status of PPP2R2B as significant predictor of overall survival and breast cancer specific survival. Conclusions In the present study we report that the level of aberrant DNA methylation is higher in late stage compared with early stage of invasive breast cancers and DCIS for genes mentioned above. PMID:24093668

  4. [Clinico-epidemiological characteristics of diseases caused by halophilic vibrios along the coast of the Sea of Azov].

    PubMed

    Shikulov, V A; Libinzon, A E; Mitsevich, G F; Koval'chuk, I A

    1987-07-01

    The epidemiological and clinical features of alimentary toxinfections caused by halophilic vibrios on the Crimean coast of the Sea of Azov at the period of 1976-1984 were studied. Toxinfections were linked mainly with the use of sea-food subjected to different kinds of culinary treatment and took the course of gastroenteritis. To prevent toxinfections caused by halophilic vibrios, the technology, as well as sanitary and hygienic norms, should be strictly observed in the production of sea-food; besides, special methods of bacteriological diagnosis should be introduced into practice at laboratories of medical institutions and fish-processing plants. PMID:2960107

  5. Clinico-pathological effects of Schistosoma mansoni infection associated with simultaneous exposure to malathion in Swiss outbred albino mice.

    PubMed

    Elsheikha, Hany M; Hussein, Hussein S; Rahbar, Mohammad H

    2008-10-01

    To investigate whether infection of Swiss outbred mice with the digenetic fluke Schistosoma mansoni is influenced by exposure to environmental pollutants, experimentally infected mice were exposed to 200 and 400 mg/kg of malathion. Pathology of liver and spleen, worm burden and levels of key hematological, biochemical and liver enzymes parameters of these mice were evaluated and were compared with data from infected, unexposed mice, uninfected, exposed mice as well as with data from uninfected, unexposed mice. Oral administration of malathion to mice infected with 20, 40 or 60 S. mansoni cercariae adversely affect architecture of liver and spleen and critically alter hematological, biochemical, histological and hepatic enzymes parameters significantly more than the controls. Alterations observed in infected, exposed mice included (i) higher mortality rate; (ii) severe pathologies in liver and spleen; (iii) increased serum level of bilirubin and alanine aminotransferase/aspartate aminotransferase (ALT/AST) enzymes; (iv) decreased serum level of albumin and total proteins; and (v) decreased red blood cell count (RBC), lymphocytes, leucocytic count, and hemoglobin content. The number of recovered adult worms of S. mansoni or their oviposition capacity did not seem to be affected with malathion treatment. Statistical analysis revealed that the increase alteration in hepatic functions is correlated with increasing the number of S. mansoni cercariae and malathion doses. Such alterations were more significant in mice treated with the higher dose of malathion or infected with the largest numbers of S. mansoni cercariae. These data indicate that schistosomiasis can be exacerbated by simultaneous malathion exposure, which in turn adversely impact the clinical and pathological outcome of the disease. PMID:18722991

  6. Clinico-Pathological Correlation of ?-Catenin and Telomere Dysfunction in Head and Neck Squamous Cell Carcinoma Patients

    PubMed Central

    Padhi, Swatishree; Saha, Arka; Kar, Madhabananda; Ghosh, Chinmoy; Adhya, Amit; Baisakh, Manas; Mohapatra, Nachiketa; Venkatesan, Shriram; Hande, Manoor Prakash; Banerjee, Birendranath

    2015-01-01

    Background: Tumorigenesis is a complex process of accumulated alteration in function of multiple genes and pathways. Wnt signalling pathway is involved in various differentiation events during embryonic development and is conserved in various species. Objective: A multicentre collaborative initiative is undertaken to study the occurrence, prognosis and molecular mechanism of HNSCC (Head and Neck Squamous Cell Carcinoma) which is highly prevalent in eastern parts of India. From a large cohort of HNSCC tissue repository, 67 cases were selected for multi-parametric investigation. Results: 67 cases showed stable ?-catenin expression. We have seen correlation, if any, of the transcription factor - ?-catenin, telomere maintenance and shelterin complex proteins - TRF2, Rap1 and hTert with respect to tumor differentiation and telomere dysfunction. Immunohistochemistry of ?-catenin protein showed stable and high expression in tumor when compared to stroma. MDSCC (Moderately Differentiated Squamous cell carcinoma) cases expressed nuclear expression of ?-catenin in invasive fronts and showed increased genomic instability. Higher frequency of Anaphase bridges was observed ranging from <3% in normal cut margin to 13% in WDSCC (Well differentiated squamous cell carcinoma) and 18% in MDSCC (Moderately differentiated Squamous cell carcinoma). There was significant decrease in telomere length in MDSCC (<4) when compared to the normal cut margin samples (<7). Quantitative Real Time-PCR confirmed a significant correlationship between stable ?-catenin expression and poor clinical and pathological outcome. Conclusion: The Stabilisation and accumulation of ?-catenin was significant and correlated well with de-differentiation process as well as prognosis and therapy outcome of the patients in the cohort. Expression status of molecular markers such as ?-catenin, hTert, TRF2 and RAP1 correlate significantly with the process of tumorigenesis and prognosis and may play a role in therapeutic management of Head and neck patients. PMID:25653721

  7. [Clinico-functional efficacy of medicinal and photon stabilization of cell membrane in patients with angina pectoris].

    PubMed

    Vasil'ev, A P; Senatorov, Iu N; Strel'tsova, N N; Gorbunova, T Iu

    2003-01-01

    Modification of erythrocytic membrane and the trend in clinicofunctional indices were studied in 90 patients with angina of effort (FC I-IV) in the course of treatment with a combination of membranoprotective drugs (group 1), magneto-laser radiation (group 2) and imitation of laser radiation (group 3). In patients of groups 1 and 2 the treatment resulted in stabilization of cell membrane accompanied with a hypotensive effect and increased exercise tolerance due to more effective cardiac performance. PMID:12650091

  8. Assessment of clinico-immunological profile of newly diagnosed HIV patients presenting to a teaching hospital of eastern India

    PubMed Central

    Bishnu, Saptarshi; Bandyopadhyay, Dipanjan; Samui, Samiran; Das, Indrani; Mondal, Pradip; Ghosh, Pramit; Roy, Deeptarka; Manna, Sukanta

    2014-01-01

    Background & objectives: Newly diagnosed HIV patients may be asymptomatic or present with a wide range of symptoms related to opportunistic infections, acute seroconversion illness or other medical illnesses. This study was designed to evaluate the socio-demographic parameters, spectrum of the presenting clinical conditions and concurrent immunological status of newly diagnosed HIV patients and document the WHO clinical stages at the time of HIV diagnosis. Methods: This cross-sectional, observational study was undertaken over a 12 month period at a tertiary referral hospital in eastern India. Three hundred sixty consecutive newly diagnosed HIV patients were selected for the study from the HIV clinic and medicine wards of this hospital. Demographic and clinical data and relevant laboratory investigations of the patients were recorded and analyzed. Results: Mean age of patients was 36.38 ± 10.62 yr, while 63.89 per cent were males. The main mode of transmission of HIV for males and females were unprotected exposure to commercial sex (139, 60.44%) and intercourse with HIV seropositive spouses (89, 68.46%), respectively. Fever (104, 28.89%), weight loss (103, 28.61%) and generalized weakness (80, 22.22%) were the predominant symptoms. Overall mean CD4 count was 176.04 ± 163.49 cells/?l (males 142.19 ± 139.33 cells/?l; females 235.92 ± 185.11 cells/?l). Overall, 224 opportunistic infections were documented in 160 patients, opportunistic diarrhoea (44, 12.22%) and pulmonary tuberculosis (39, 10.83%) being the commonest. There were 83 and 133 patients in WHO clinical stages 3 and 4, respectively; 291 (80.83%) patients were eligible for initiation of first-line antiretrovirals at presentation. Interpretation & conclusions: Advanced immunodeficiency and burden of opportunistic infections characterize newly diagnosed HIV patients in eastern India. The physicians should keep in mind that these patients may have more than one clinical condition at presentation. PMID:25109725

  9. Experimentally induced tick toxicosis in rats bitten by Ornithodoros brasiliensis (Chelicerata: Argasidae): a clinico-pathological characterization.

    PubMed

    Reck, José; Bandarra, Paulo; Pavarini, Saulo; Termignoni, Carlos; Driemeier, David; Martins, João Ricardo; Guimarães, Jorge A

    2014-09-01

    Ornithodoros brasiliensis, also known as the mouro tick, is an argasid tick only found in the highlands of Southern Brazil. O. brasiliensis parasitism is associated with severe reactions in its hosts ranging from local pruritus and pain to systemic disturbances. Recently, the re-emergence of O. brasiliensis parasitism in humans and dogs drew attention to the clinical findings induced by its bite, which are poorly understood and described. Moreover, rare experimental data about tick bite effects under controlled conditions were available. Thus, this study aimed to describe clinical and pathological findings induced by O. brasiliensis bites in experimentally parasitized rats. Ticks feed for ?40 min in rats, and their weight increased by approximately four times after the blood meal. Rats bitten by five adult ticks showed hyperemia of the oral/ocular mucosa, piloerection, tachypnea, claudication, ocular and nasal discharge, pruritus, and swollen and erythemic lesions. A large hemorrhagic lesion was observed on rat skin in tick attachment sites, reaching ?17 mm in diameter 12 h after a bite. Bitten rats also presented an increased bleeding tendency (?50%) 6 h after a tick bite, evaluated by the tail-cut rat model of bleeding. Blood samples of bitten rats were taken, and clinical pathology analysis showed significant alterations in the eosinophil and basophil counts, in creatine phosphokinase (CPK) and CPK MB fraction, and lactate dehydrogenase (LDH) activity, and fibrinogen level. Histopathological analysis revealed marked subcutaneous hemorrhage, edema and slight muscle degeneration at the bite site. Also, muscle degeneration and necrosis were observed in the myocardium of bitten rats 72 h after bites by histopathology and immunohistochemistry against troponin C. This work showed the ability of O. brasiliensis to cause severe disturbances in experimentally parasitized rats, compatible with a tick toxicosis syndrome. This observation associated with the re-emergence of O. brasiliensis parasitism makes this parasite as a public health hazard in southern Brazil. PMID:24973739

  10. Analysis of the clinico-hematological relevance of the breakpoint location within M-BCR in chronic myeloid leukemia.

    PubMed

    Bennour, Ayda; Ouahchi, Ines; Achour, Bechir; Zaier, Monia; Youssef, Yosra Ben; Khelif, Abderrahim; Saad, Ali; Sennana, Halima

    2013-03-01

    The Philadelphia chromosome (Ph) derives from the balanced translocation between chromosomes 9 and 22. This chromosomal translocation results in the fusion between the 5' part of the BCR gene, normally located on chromosome 22, and the 3' part of the ABL gene on chromosome 9 giving origin to a BCR-ABL fusion gene which is transcribed and then translated into a hybrid protein. In general, three breakpoint cluster regions in the BCR gene have been described: major (M-BCR), minor (m-BCR) and micro (?-BCR). Three main variants of the BCR-ABL gene have been described depending on the length of the sequence of the BCR gene included that encode for the P190, P210, P230 proteins. Most patients (95 %) were found to have P210 protein that resulted from rearrangement in the M-BCR region in the BCR gene and thus gives rise to b2a2 or b3a2 variants. The incidence of one or other rearrangement in chronic myeloid leukemia (CML) patients varies in different reported series. These two variants are associated with distinct clinical types of human leukemias. In this study, we report the frequencies of M-BCR-ABL fusion transcripts in 44 CML patients and we review the data on the correlations between the type of M-BCR/ABL variant and the corresponding sex, age and biological features. Forty-four untreated chronic phase CML patients were studied. The type of BCR-ABL fusion transcripts was determined by reverse transcriptase polymerase chain reaction (RT-PCR). More than half of them showed b3a2 fusion transcript (64 %), while (36 %) showed b2a2 transcript. No patients coexpressed b3a2/b2a2. Correlation between biological data demonstrated that: (a) M-BCR rearrangements were not associated with the sex of the patients. (b) Patients with b3a2 rearrangements were older than patients with b2a2 transcripts. (c) M-BCR rearrangements were influenced neither by the white blood count (WBC) nor with hemoglobin levels. However, platelet level is more elevated in patients with b3a2 transcript (681.2/L vs. 207/L; P = 0.001). In conclusion, we observed significant correlations between age, platelet level and M-BCR-ABL transcript, these observations deserve further investigations. PMID:23269583

  11. Primary neuroendocrine mediastinal tumor presenting with carcinoid syndrome and left supraclavicular lymphadenopathy: clinico-radiological and pathological features.

    PubMed

    Dwivedi, Amit Nandan D; Goel, Kanika; Tripathi, Suchi; Garg, Sunny; Rai, Madhukar

    2013-01-01

    Primary mediastinal neuro-endocrine tumor is very rare. The primary modality to evaluate the lesion is computed tomography, to know disease extent, involvement of various structures, vascular invasion and metastasis. Histo-pathological and immuno-histochemical confirmation is mandatory. We report a rare case of primary neuroendocrine mediastinal tumor/atypical carcinoid in a young male who presented with carcinoid syndrome and left supraclavicular lymphadenopathy. Complete diagnostic work up was done followed by histo-pathological and immuno-histochemical confirmation. Later on patient underwent radical surgery followed by chemotherapy. The patient is currently on follow up. Neuroendocrine carcinoma of the thymus generally follows an aggressive clinical course.The biologic behavior is directly related to grade and degree of differentiation. This case report of primary low grade neuroendocrine tumor/atypical carcinoid adds to the biological behavior of this tumor and sheds light on the radiological and pathological features of neuroendocrine carcinomas. PMID:23771374

  12. Clinico-radiological assessment and their correlation in clubfeet treated with postero-medial soft-tissue release.

    PubMed

    Prasad, Prabhudev; Sen, Ramesh K; Gill, Shivender S; Wardak, Emal; Saini, Raghav

    2009-02-01

    The controversy regarding the radiographic parameter which best represents the various deformities of clubfoot continues. The aim of our study was to clear up this controversy. Fifty surgically treated (soft-tissue release) congenital clubfeet were studied clinically using Laaveg and Ponseti score and radiologically using twelve different radiographic parameters in weight-bearing AP and lateral views. The talo-calcaneal angle (TCA) in AP and lateral view showed statistically significant correlation with the functional rating, but significant variation in the dimension of the angles among the different functional groups was found with AP angle only. The talo-first metatarsal angle in AP and lateral view averaged 10 degrees and 19 degrees respectively, and showed significant correlation with the functional rating. The talo-navicular subluxation in AP, the calcaneo-fifth metatarsal angle and the first-fifth metatarsal angle in lateral view did not show any significant correlation with function. Talo-calcaneal index averaged 44 degrees in the clubfeet and showed significant correlation. The wide range of parameters representing each of the deformities gives a better radiological assessment of the clubfoot than any single parameter. PMID:17768623

  13. Lymphocyte-rich classical Hodgkin lymphoma (LRCHL): clinico-pathological characteristics and outcome of a rare entity

    Microsoft Academic Search

    D. de Jong; J. Bosq; K. A. MacLennan; J. Diebold; J. Audouin; J. Chasle; A.-M. Mandard; J. Marnay; M. Henry-Amar

    2005-01-01

    Background: To investigate the proportion, clinical characteristics and outcome of lymphocyte-rich classical Hodgkin lymphoma (LRCHL) in relation to nodular lymphocyte predominant HL (NLPHL) and classical HL (cHL). Patients and methods: A series of 2743 HL patients of all stages enrolled into three EORTC trials (H7, H8, H34) conducted between 1988 and 2000 and forming an unbiased series of HL patients

  14. [The clinico-epidemiological aspects of tuberculosis occurring in medical personnel in pneumophthisiology units in Bucharest (1992-1996)].

    PubMed

    Ibraim, E; Didilescu, C; Micu, E

    1998-01-01

    The authors studied 38 TB cases diagnosed between 1992 and 1996 among the 1092 employees (medical and nonmedical) of the pneumophthisiology departments in Bucharest (hospitals and ambulatory units). Most cases had pulmonary involvement (76.3%), 85.7% were bacteriologically tested for bK. Among them, 66.7% were confirmed. The therapeutic results evaluated after 1 year, showed just 1 failure. The medium annual risk of tuberculosis at the PF personnel is corresponding to an incidence of 700/100,000 (6.36 times higher than TB incidence in general population). This conclusions calls for emergency measures for protecting and compensating this personnel. PMID:10386148

  15. Clinico-pathological effects of Schistosoma mansoni infection associated with simultaneous exposure to malathion in Swiss outbred albino mice

    Microsoft Academic Search

    Hany M. Elsheikha; Hussein S. Hussein; Mohammad H. Rahbar

    2008-01-01

    To investigate whether infection of Swiss outbred mice with the digenetic fluke Schistosoma mansoni is influenced by exposure to environmental pollutants, experimentally infected mice were exposed to 200 and 400mg\\/kg of malathion. Pathology of liver and spleen, worm burden and levels of key hematological, biochemical and liver enzymes parameters of these mice were evaluated and were compared with data from

  16. A clinico-epidemiological analysis of Helicobacter pylori (H. pylori) by Southern blotting with A urease gene probe

    Microsoft Academic Search

    Yasushi Tonokatsu; Tomoko Hayashi; Yoshihiro Fukuda; Toshihide Tamura; Takashi Shimoyama

    1994-01-01

    Helicobacter pylori (H. pylori) is a gramnegative bacillus thought to be involved in such diseases of the upper gastrointestinal tract as gastritis, peptic\\u000a ulcers, and gastric cancer. Urease is regarded as the factor responsible for the pathogenic nature of this bacterium. Therefore,\\u000a in our examination of the genetic polymorphism ofH. pylori, by means of Southern blotting, we used the urease

  17. Clinico-pathological association of Henoch-Schoenlein purpura nephritis and IgA nephropathy in children

    PubMed Central

    Mao, Song; Xuan, Xiaoyan; Sha, Yugen; Zhao, Sanlong; Zhu, Chunhua; Zhang, Aihua; Huang, Songming

    2015-01-01

    Objective: Henoch-Schonlein purpura nephritis (HSPN) and IgA nephropathy (IgAN) are similar syndromes. We aimed to determine whether the crescent formation/immunocomplex in glomeruli is associated with the differences of the biochemical indexes between HSPN and IgAN. Methods: We investigated the medical records of 137 HSPN cases and 41 IgAN cases from January 2009 to April 2014 in Nanjing Children’s Hospital of Nanjing Medical University. The clinical and pathological data were analyzed and compared between HSPN and IgAN. Results: HSPN patients had markedly higher levels of blood white blood cell (WBC), hemoglobulin (Hb) and platelet (PLT), lower levels of hematuria, blood nitrogen (BUN) and C4 compared with IgAN cases. Crescents formation and C3 deposition in the kidney did not affect these differences. Significantly lower levels of hematuria, blood IgG, IgM and C4 in HSPN compared with IgAN cases were observed among patients with IgG deposition. Markedly higher levels of WBC and Hb, lower levels of hematuria, creatinine (Cr), C4 in HSPN compared with IgAN cases were observed among patients with IgM deposition. No marked differences of the biochemical indexes were noted between HSPN and IgAN cases among patients with C1q deposition. Markedly higher levels of WBC and Hb, lower level of blood C4 in HSPN compared with IgAN cases were observed among patients with fibrogen deposition. Conclusions: The different levels of biochemical indexes at presentation between HSPN and IgAN may be associated with the deposition of IgG, IgM, C1q and fibrogen in the kidney.

  18. Physicochemical and clinico-immunologic studies on the allergenic significance of Aspergillus tamarii, a common airborne fungus

    Microsoft Academic Search

    Maansi Vermani; Vannan K. Vijayan; Balakrishnan Menon; Mohd A. Kausar; Mahendra K. Agarwal

    2011-01-01

    Aspergillus-derived inhalant allergens play an important role in the etiology of allergic respiratory diseases. In the present study, we investigated the allergenic potential of Aspergillus tamarii, quantified its airborne content, identified its major\\/minor allergens, evaluated heterogeneity of patients’ IgE response to its allergens and cross-reactivity of its allergens with other Aspergillus allergens. Skin prick tests with A tamarii extract were

  19. Clinico-mycological Profile of Dermatophytosis in a Reference Centre for Leprosy and Dermatological Diseases in Addis Ababa

    Microsoft Academic Search

    Y. Woldeamanuel; R. Leekassa; E. Chryssanthou; Y. Mengistu; B. Petrini

    2006-01-01

    To assess the clinical and fungal species spectrum of dermatophyte infection in a reference centre in Addis Ababa, 539 dermatological\\u000a patients with signs of dermatophytosis were investigated. Seventy-one percent were female and 29% male, aged 2–66 years (median\\u000a 9). Four hundred-fifteen (77%) had at least one skin lesion. Tinea capitis was diagnosed in 138\\/155 males (89%) as compared to 214\\/384 females

  20. Insulin-like growth factors in endometrioid adenocarcinoma: Correlation with clinico-pathological features and estrogen receptor expression

    PubMed Central

    2012-01-01

    Background Endometrial carcinoma is a common malignancy of female genital tract. Insulin-like growth factor is known to elicit estrogen-induced mitogenic activity and anti-apoptotic effect in endometrial tissues. Methods The retrospective study investigated the expression of insulin-like growth factors, estrogen receptors and their associations in endometrioid adenocarcinoma (EAC) from 80 EAC patients in immunohistochemistry, and 58 EAC patients and 42 control patients in quantitative RT-PCR. The Pearson correlation analysis was used to analyze their correlations with clinic-pathological parameters. Results Our results showed that insulin-like growth factor-1 and insulin-like growth factor-2 mRNA levels were higher in tumor tissues and tumor-adjacent tissues than those in control cells, and were inversely correlated with the malignancy of the tumor with a positive correlation with ER? and ER? expression. Insulin-like growth factor-1R protein expression was correlated with clinical stage, and insulin-like growth factor-2R protein expression was inversely correlated with histological grade. Conclusions Insulin-like growth factor system plays an important role in estrogen-induced endometrial carcinogenesis, and overexpression of insulin-like growth factor-1R in the advanced endometrioid adenocarcinoma is not estrogen-dependent. PMID:22720981

  1. Clinico-histopathologic and outcome features of cutaneous infundibular keratinizing acanthoma: a case report and literature review

    PubMed Central

    2014-01-01

    The infundibular keratinizing acanthoma (IKA) is a rare epithelial benign keratin-containing neoplasm of hair follicles. The purpose of this study was to evaluate the defining histopathologic architecture of IKA. A typical IKA consisted of a keratin-filled crypt in the dermis and subcutis that opened to the skin surface. Most of this tumor occurred on the back, neck, head, and the shoulders. Microscopically, the dermal nodules were focally contiguous in both the dermis and subcutis. Furthermore, most histological lesions are consistent with a simple or multiloculated cyst filled with keratin and lined by a wall of stratified squamous epithelium; keratin appears as a concentric lamellar mass, with a keratotic pearly aspect. Histological examination of the cutaneous lesions revealed that the growths were comprised of IKA. IKA of man and dog were compared, and it was concluded that although they are similar in many respects, they are not identical entities. To the best of our knowledge, this is the first report on the prevalence of IKAs among the population of owned dogs in Iran. PMID:24890648

  2. Clinico-pathological profile of acute promyelocytic leukaemia at Al-Amal Oncology-Haematology Centre, Qatar.

    PubMed

    Ibrahim, F A; Yassin, M A; El-Ayoubi, H R; Alhiji, I A; Albinali, A S; Almansour, S M; Qafoud, F M

    2010-09-01

    This cases series describes the profile of adult patients with acute promyelocytic leukaemia (APt) at a referral hospital in Qatar. Of 34 acute myeloid leukaemia (AML) cases diagnosed, 11(32%) were classified as APt. Disseminated intravascular coagulation was common at presentation (91%). Severe thrombocytopenia was seen in 73%, leukocytosis in 55% and severe anaemia in 45%. Only 2 patients were of the classic hypergranular type. In the remaining 9 patients, 3 morphological subtypes were recognized: microgranular variant (6 patients), hyperbasophilic (2 patients) and regular nuclear outline M3r (1 patient). Translocation t(15;17) was detected in 63% of cases. APL constitutes a high proportion of AML cases in Qatar, with considerable morphological heterogeneity and a oredominance of APL variants with unfavourable oresenting features. PMID:21218723

  3. Histopathologic spectrum of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): a diagnosis that needs clinico-pathological correlation.

    PubMed

    Borroni, G; Torti, S; Pezzini, C; Vassallo, C; Rosso, R; D'Ospina, R M; Tomasini, C; Brazzelli, V

    2014-06-01

    Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) is characterized by an heterogeneous group of severe dermatologic manifestations and systemic involvement, due to several groups of medicaments. A series of 9 consecutive cases, observed from 2008 to 2013 in the Department of Dermatology, University of Pavia, is reported, all satisfying the clinical, hematological and systemic diagnostic criteria of DRESS. Clinically, 4 out of 9 patients had an urticarial and papular eruption, 2 an erythema-multiforme-like (EM-like) pattern, 2 erythroderma and 1 had an erythematous and macular reaction. Aim of the study was to describe the histopathologic features of DRESS and to trace a possible correlation between the four clinical recognized types of the syndrome and the histopathological patterns. Predominantly, a superficial perivascular lymphocytic infiltrate, extravasation of erythrocytes, and focal interface changes characterized DRESS cases. Less frequently, histopathology revealed the presence of necrotic keratinocytes; surprisingly, only in 2 cases the presence of rare dermal eosinophils was detected, even if all the patients had significant peripheral eosinophilia. A histopathological diagnosis of DRESS seems per se, according to our data, not feasible, since the main histopathological changes (interface changes, superficial perivascular dermatitis, focal spongiosis, lichenoid infiltrate, rare presence of necrotic keratinocytes) can be interpreted generically as a drug induced dermatitis. The above mentioned histopathological changes, however, when associated with clinical information on cutaneous and systemic involvement of the patient, allow the pathologist or the dermatopathologist to make a diagnosis of DRESS with a reliable margin of certainty. PMID:24819756

  4. Dependence of the seal property of ConFlat-type flanges on the fine dimensions of the knife edge

    NASA Astrophysics Data System (ADS)

    Kurokouchi, Satoshi; Shinoda, Satsuo; Morita, Shinsaku

    2003-03-01

    The shape of the sealing face on ConFlat-type flanges has not been addressed at all in the International Standards Organization standards, yet it is the distinct shape of the sealing face on the flange, generally referred to as the "knife edge" that primarily distinguishes the ConFlat sealing system. Results of profiling on the sealing face of 70 mm diameter ConFlat-type flanges, provided by ten individual manufacturers, reveal that while all the sealing faces share a common 20deg angle on the taper face, there are variations in the tip radius of the knife edge, and in the angle of the counterslope against the 20deg taper face. In flange tightening tests using the ConFlat flanges, the tip radius was observed to influence flange penetration into the gasket. It was also determined that the knife edges of all the test flanges were plastically deformed to some extent in the process of tightening twice at a torque of 120 kgf cm. The knife-edge shape was neither found to be dependent on the magnitude of deformation, nor did the deformation have an observable influence on the seal property. In order to closely investigate the dependence of the ConFlat-type flange seal property on the fine shape of its sealing face, four types of 152 mm diameter flanges, each with a different knife-edge shape, were subjected to flange tightening tests. The results indicated that flanges with a small tip radius and a small counterslope angle maintained a satisfactory seal ability, even when applied tightening torque was lower, but had difficulty retaining sealing stability under an elevated temperature. On the other hand, flanges with a large tip radius or large counterslope angle on the knife edge had an advantage in terms of seal stability in baking conditions, but required relatively higher tightening torque to attain secure sealing. To evaluate the tip radius and the counterslope angle at which the flange seal capability and the sealing stability at an elevated temperature are in goo

  5. Fuentes de variabilidad en el diagnóstico de gastritis atrófica multifocal asociada con la infección por Helicobacter pylori1

    PubMed Central

    Bravo, Luis Eduardo; Bravo, Juan Carlos; Realpe, José Luis; Zarama, Guillermo; Piazuelo, MarÍa Blanca; Correa, Pelayo

    2014-01-01

    RESUMEN Introducción El mapeo de las diferentes regiones del estómago y el número de fragmentos de mucosa gástrica disponibles para evaluación histopatológica son fuentes importantes de variación en el momento de clasificar y hacer la gradación de la gastritis crónica. Objetivos Estimar la sensibilidad del número de fragmentos de mucosa gástrica necesarios para establecer los diagnósticos de gastritis atrófica con metaplasia intestinal (MI), displasia y estado de infección por Helicobacter pylori. Además evaluar la variabilidad intra-observador en la clasificación de estas lesiones precursoras del cáncer gástrico. Materiales y métodos En una cohorte de 6 años de seguimiento se evaluaron 1,958 procedimientos de endoscopia realizados por dos gastroenterólogos. En cada procedimiento y de cada participante se obtuvieron 5 biopsias de mucosa gástrica que representaban antro, incisura angularis y cuerpo. Un único patólogo hizo la interpretación histológica de las 5 biopsias y proporcionó un diagnóstico definitivo global que se utilizó como patrón de referencia. Cada fragmento de mucosa gástrica examinado condujo a un diagnóstico individual para cada biopsia que se comparó con el patrón de referencia. La variabilidad intra-observador se evaluó en 127 personas que corresponden a una muestra aleatoria de 20% del total de endoscopias hechas a los 72 meses de seguimiento. Resultados La sensibilidad del diagnóstico de MI y displasia gástrica aumentó de manera significativa con el número de fragmentos de mucosa gástrica evaluados El sitio anatómico de mayor sensibilidad para el diagnóstico de MI y displasia fue la incisura angularis. Para descubrir H. pylori se logró alta sensibilidad con el estudio de un solo fragmento de mucosa gástrica (95.9%) y fue independiente del sitio de obtención de la biopsia. El acuerdo intra-observador para el diagnóstico de gastritis crónica fue 86.1% con valor kappa de 0.79 IC 95% (0.76-0.85). Las biopsias fijadas en alcohol fueron inadecuadas para demostrar H. pylori e interpretar los cambios de displasia. Conclusión El número de fragmentos de mucosa gástrica evaluados, el método de fijación y la región del estómago donde se obtienen las biopsias son factores muy importantes para lograr una correcta clasificación de la gastritis crónica atrófica multifocal. PMID:25267864

  6. Anti-human IG and B lymphocytes reconstitute the proliferative response to Con A of T lymphocytes depleted of accessory cells

    SciTech Connect

    Tsuda, T.; Kim, Y.T.; Schwab, R.; Siskind, G.W.; Weksler, M.E.

    1986-03-01

    The requirements for the induction of proliferation of human peripheral blood mononuclear cells (PBM) by low concentrations of Concanavalin A (Con A) were studied using /sup 3/H-thymidine incorporation to assay DNA synthesis. Removal of plastic-adherent cells from PBM reduced the proliferative response of lymphocytes to Con A by 80%. Passage of these cells over nylon wool columns totally eliminated their response to Con A. Addition of adherent monocytes or rabbit anti-human IgG conjugated to polyacrylamide beads (anti-IgG beads) to the non-adherent lymphocyte population reconstituted the proliferative response. The lymphoblasts activated in these cultures were more than 90% T11 positive. Anti-IgG beads did not activate lymphocyte proliferation in the absence of Con A. The response of non-adherent lymphocytes to Con A could also be reconstituted by unconjugated rabbit anti-human IgG antiserium. Purified T cells could only be activated by anti-IgG beads and low concentrations of Con A in the presence of irradiated B cells. These results suggest that /sup 3/H-thymidine incorporation by T cells induced by anti-IgG beads and a low concentration of Con A depends on the interaction of anti-IgG and B cells. The authors suggest that B cell produce growth factors for T cells after interacting with anti-IgG.

  7. Biological effects of Escherichia coli lipopolysaccharide (LPS) in vivo. II. Selection in the mouse thymus of PHA- and con A-responsive cells.

    PubMed Central

    Adorini, L; Ruco, L; Uccini, S; De Franceschi, G S; Baroni, C D; Doria, G

    1976-01-01

    The effect of LPS injection on mouse thymocytes was examined by in vitro stimulation with PHA and Con A. Thymocytes from LPS treated mice were found more responsive than normal thymocytes to PHA and Con A. The increase of responsiveness was different for PHA and Con A, and dependent on the dose of LPS injected. This dose dependency suggests that LPS in vivo modifies the thymocyte population by progressively eliminating T1 cells and selecting T2 cells. These effects seem to be mediated by corticosteroids because they were prevented by adrenalectomy, a finding in agreement with the notion that the injection of cortisone induces similar cell changes in the thymus. PMID:783042

  8. Integrated Concentration in Science (iCons): Undergraduate Education Through Interdisciplinary, Team-Based, Real-World Problem Solving

    NASA Astrophysics Data System (ADS)

    Tuominen, Mark

    2013-03-01

    Attitude, Skills, Knowledge (ASK) - In this order, these are fundamental characteristics of scientific innovators. Through first-hand practice in using science to unpack and solve complex real-world problems, students can become self-motivated scientific leaders. This presentation describes the pedagogy of a recently developed interdisciplinary undergraduate science education program at the University of Massachusetts Amherst focused on addressing global challenges with scientific solutions. Integrated Concentration in Science (iCons) is an overarching concentration program that supplements the curricula provided within each student's chosen major. iCons is a platform for students to perform student-led research in interdisciplinary collaborative teams. With a schedule of one course per year over four years, the cohort of students move through case studies, analysis of real-world problems, development of potential solutions, integrative communication, laboratory practice, and capstone research projects. In this presentation, a track emphasizing renewable energy science is used to illustrate the iCons pedagogical methods. This includes discussion of a third-year laboratory course in renewable energy that is educationally scaffolded: beginning with a boot camp in laboratory techniques and culminating with student-designed research projects. Among other objectives, this course emphasizes the practice of using reflection and redesign, as a means of generating better solutions and embedding learning for the long term. Attitude, Skills, Knowledge (ASK) - In this order, these are fundamental characteristics of scientific innovators. Through first-hand practice in using science to unpack and solve complex real-world problems, students can become self-motivated scientific leaders. This presentation describes the pedagogy of a recently developed interdisciplinary undergraduate science education program at the University of Massachusetts Amherst focused on addressing global challenges with scientific solutions. Integrated Concentration in Science (iCons) is an overarching concentration program that supplements the curricula provided within each student's chosen major. iCons is a platform for students to perform student-led research in interdisciplinary collaborative teams. With a schedule of one course per year over four years, the cohort of students move through case studies, analysis of real-world problems, development of potential solutions, integrative communication, laboratory practice, and capstone research projects. In this presentation, a track emphasizing renewable energy science is used to illustrate the iCons pedagogical methods. This includes discussion of a third-year laboratory course in renewable energy that is educationally scaffolded: beginning with a boot camp in laboratory techniques and culminating with student-designed research projects. Among other objectives, this course emphasizes the practice of using reflection and redesign, as a means of generating better solutions and embedding learning for the long term. This work is supported in part by NSF grant DUE-1140805.

  9. CORSI DI STUDIO AD ACCESSO CON VERIFICA DEI SAPERI MINIMI A.A. 2013-2014 AREA "LINGUE E LETTERATURE STRANIERE" -PROVA DI LINGUA INGLESE

    E-print Network

    Romeo, Alessandro

    CORSI DI STUDIO AD ACCESSO CON VERIFICA DEI SAPERI MINIMI A.A. 2013-2014 AREA "LINGUE E LETTERATURE STRANIERE" - PROVA DI LINGUA INGLESE Il superamento della prova dei "Saperi Minimi" è condizione necessaria

  10. El seminario consta de dos partes independientes: Una primera parte o Seminario terico con el ttulo Comprendiendo elTDA-H y una segunda

    E-print Network

    Escolano, Francisco

    : · AnalizarlarealidaddelossujetosconTDAH,desdesuprimera infancia hasta la entrada en la edad adultaTDAH. ·Promovercompetenciasenelalumnadoquelespermitadesarrollar las aptitudes de los menores conTDAH, para desenvolverse mejor por las diferentes trayectorias

  11. Es un placer para nosotros compartir con vosotros el I Concurso de Programacin en Visual Cobol que AnyHelp Int. lanza junto a Micro Focus,

    E-print Network

    Rey Juan Carlos, Universidad

    Es un placer para nosotros compartir con vosotros el I Concurso de Programación en Visual Cobol que informática del entorno universitario o de Formación profesional que desarrollen aplicaciones en Visual Cobol

  12. Dietary n-3 PUFA Protects Mice from Con A Induced Liver Injury by Modulating Regulatory T Cells and PPAR-? Expression

    PubMed Central

    Sui, Yongheng; Li, Zhiping; Hua, Jing

    2015-01-01

    Background Dietary n-3 polyunsaturated fatty acids (PUFA) exert anti-inflammatory and immunoregulatory effects through down-regulating the innate and adoptive immune response. However, the effect of dietary n-3 PUFA on CD4+CD25+ regulatory T cells (Tregs) is unclear. Aims The current study was to examine the relationship between n-3 PUFA and Tregs as well as their immunoregulatory effect in immune-mediated liver injury. Methods The mice model feeding with n-3 PUFA-enriched diet was established and Tregs were analyzed. Effect of docosahexaenoic acid (DHA) on Tregs proliferation and induction was determined in vitro. The potential immunotherapeutic effect of dietary n-3 PUFA was investigated through Con A-induced hepatitis model. Results Long-term administration of dietary n-3 PUFA significantly increased hepatic Tregs and modulated their phenotype. n-3 PUFA or DHA directly increased natural Tregs (nTreg) proliferation but didn’t increase inducible Tregs (iTreg). In addition, the expression of peroxisome proliferator activated receptor gamma (PPAR-?), transforming growth factor ? (TGF-?) and interleukin (IL)-10 were significantly up-regulated in n-3 PUFA-enriched diet-fed mice. Finally, n-3 PUFA-enriched diet alleviated liver injury induced by Con A and down-regulated pro-inflammatory cytokines expression, accompanied by increased PPAR-? expression. Conclusion Dietary n-3 PUFA enhanced Tregs generation through up-regulating PPAR-? and TGF-? expression, and protected mice from Con A-induced liver injury. This finding provides a promising potential therapeutic method in treating inflammatory and autoimmune disease. PMID:26177196

  13. Errores sistemáticos del Catálogo Fundamental FK5, deducidos de las observaciones con Astrolabio Fotoeléctrico PAII, en el Hemisferio Sur

    NASA Astrophysics Data System (ADS)

    Manrique, W. T.; Podestá, R. C.; Alonso, E.; Actis, E. V.; Pacheco, A. M.; Bustos, G.; Lizhi, L.; Zezhi, W.; Fanmiao, Z.; Hongqi, W.; Perdomo, R.; González, A.; Gómez, G.

    Se dan los resultados obtenidos de los Errores Sistemáticos del Catálogo Fundamental FK5, ? ? ?, ? ? ?, ? ? ? y ? ? ?, derivados de las observaciones estelares con el Astrolabio Fotoeléctrico PAII del Observatorio de Beijing instalado en el Observatorio Astronómico ``Félix Aguilar'' de San Juan, de acuerdo al Proyecto de Colaboración entre los observatorios de San Juan, Beijing y La Plata. Se han usado los residuos seleccionados de 11000 estrellas aproximadamente, derivados de más de 400000 pasajes estelares en 1550 días, desde Febrero de 1992 a Marzo de 1997. La precisión media de los residuos es de 0,"043.

  14. Comparison of hydrogenated amorphous silicon germanium and nanocrystalline silicon for multijunction solar cells: pros, cons, and status

    Microsoft Academic Search

    Jeffrey Yang; Baojie Yan; Guozhen Yue; Subhendu Guha

    2005-01-01

    A comparison is made of hydrogenated amorphous silicon germanium (a-SiGe:H) and hydrogenated nanocrystalline silicon (nc-Si:H) for use in the bottom cell of a multijunction structure. In our laboratory, an initial active-area cell efficiency of 14.6% has been achieved in both a-Si:H\\/a-SiGe:H\\/a-SiGe:H and a-Si:H\\/a-SiGe:H\\/nc-Si:H triple-junction structures. Their light-soaked stabilized efficiencies are also similar. Pros, cons, issues, and status for using these

  15. ConPas: a 3-D Conformal Parotid Gland-Sparing Irradiation Technique for Bilateral Neck Treatment as an Alternative to IMRT

    Microsoft Academic Search

    Ruud Wiggenraad; Mirjam Mast; Jan van Santvoort; Marc Hoogendoorn; Henk Struikmans

    2005-01-01

    \\u000a Background and Purpose:  Intensity-modulated radiotherapy (IMRT) is used in most reported techniques for bilateral neck irradiation that aim at parotid\\u000a gland sparing. A relatively simple conformal parotid-sparing technique (ConPas) was developed that uses no beam-intensity modulation. The purpose of this paper is to demonstrate,\\u000a in patients with larynx or hypopharynx carcinoma, that ConPas enables adequate coverage of the primary tumor and

  16. Ground-state magnetic properties of CoN clusters on Pd(111): Spin moments, orbital moments, and magnetic anisotropy

    NASA Astrophysics Data System (ADS)

    Félix-Medina, R.; Dorantes-Dávila, J.; Pastor, G. M.

    2003-03-01

    The ground-state spin moments , orbital moments , and magnetic anisotropy energy (MAE) of CoN clusters deposited on the Pd(111) surface are determined in the framework of a self-consistent, real-space tight-binding method. Two-dimensional CoN/Pd(111) with N<~13 show remarkably large total magnetic moments per Co atom Mz=(2+)/N=(2.4 2.7)?B, which are the result of three physically distinct effects. The first and leading contribution comes, as expected, from the local spin moments at the Co atoms i=1-N [2Co?1.7?B]. Second, significant spin moments are induced at the Pd atoms i>N close to the Co-Pd interface, which amount to about 20% of Mz [2Pd=(0.2 0.3)?B]. Finally, remarkably enhanced orbital magnetic moments are found that are responsible for approximately 20% of Mz. In the case of Co atoms, Co?(0.3 0.5)?B is almost a factor of 3 larger than the Co-bulk orbital moment, while in Pd atoms Pd=(0.02 0.04)?B represents about 10% of the total local moment ?iz=2+. The dependence of the orbital moments on the orientation of the magnetization with respect to the cluster structure is quantified. These results and the associated MAEs are analyzed from a local point of view. One- and two-dimensional (2D) CoN are considered in order to investigate the structural dependence of the magnetic behavior. The role of the cluster-surface interactions is discussed by comparison with free cluster calculations. In particular, we observe that the lowest-energy magnetization direction (easy axis) changes from in-plane to off-plane upon deposition of 2D CoN on Pd(111). Cluster-substrate hybridizations are therefore crucial for the magnetoanisotropic behavior of magnetic islands deposited on metallic substrates.

  17. Protection from concanavalin A (Con A)-induced T cell-dependent hepatic lesions and modulation of cytokine release in mice by sodium fusidate.

    PubMed

    Nicoletti, F; Beltrami, B; Raschi, E; Di Marco, R; Magro, G; Grasso, S; Bendtzen, K; Fiorelli, G; Meroni, P L

    1997-12-01

    The immunomodulatory effects of the antibiotic sodium fusidate (SF) were tested in a model of T cell-dependent hepatic injury that can be induced in normal mice by a single i.v. injection of Con A. Signs of hepatitis with elevated transaminase activities in plasma, severe infiltration of the liver by neutrophil granulocytes, lymphocytes and monocytes, and necrotic areas were observed in control mice treated intraperitoneally with PBS 24 h and 1 h before Con A challenge. T cell- and macrophage-derived cytokines (IL-2, interferon-gamma (IFN-gamma), tumour necrosis factor-alpha (TNF-alpha, IL-1beta, IL-6) were released with different kinetics in the circulation of these mice. SF, 20, 40 or 80 mg/kg, administered 24 h and 1 h before Con A challenge, protected the mice against the hepatitic effects of Con A. The protective effects of SF were dose-dependent and accompanied by profound modifications of blood levels of cytokines induced by Con A, so that, relative to control mice, SF (80 mg/kg)-treated animals showed markedly diminished plasma levels of IL-2, IFN-gamma and TNF-alpha, along with augmented levels of IL-6. These results suggest that SF might be useful in the treatment of immunoinflammatory liver diseases in humans. PMID:9409654

  18. Protection from concanavalin A (Con A)-induced T cell-dependent hepatic lesions and modulation of cytokine release in mice by sodium fusidate

    PubMed Central

    NICOLETTI, F; BELTRAMI, B; RASCHI, E; DI MARCO, R; MAGRO, G; GRASSO, S; BENDTZEN, K; FIORELLI, G; MERONI, P L

    1997-01-01

    The immunomodulatory effects of the antibiotic sodium fusidate (SF) were tested in a model of T cell-dependent hepatic injury that can be induced in normal mice by a single i.v. injection of Con A. Signs of hepatitis with elevated transaminase activities in plasma, severe infiltration of the liver by neutrophil granulocytes, lymphocytes and monocytes, and necrotic areas were observed in control mice treated intraperitoneally with PBS 24 h and 1 h before Con A challenge. T cell- and macrophage-derived cytokines (IL-2, interferon-gamma (IFN-?), tumour necrosis factor-alpha (TNF-?), IL-1?, IL-6) were released with different kinetics in the circulation of these mice. SF, 20, 40 or 80 mg/kg, administered 24 h and 1 h before Con A challenge, protected the mice against the hepatitic effects of Con A. The protective effects of SF were dose-dependent and accompanied by profound modifications of blood levels of cytokines induced by Con A, so that, relative to control mice, SF (80 mg/kg)-treated animals showed markedly diminished plasma levels of IL-2, IFN-? and TNF-?, along with augmented levels of IL-6. These results suggest that SF might be useful in the treatment of immunoinflammatory liver diseases in humans. PMID:9409654

  19. Protective Effects of Astaxanthin on ConA-Induced Autoimmune Hepatitis by the JNK/p-JNK Pathway-Mediated Inhibition of Autophagy and Apoptosis

    PubMed Central

    Liu, Tong; Wang, Junshan; Dai, Weiqi; Wang, Fan; Zheng, Yuanyuan; Chen, Kan; Li, Sainan; Abudumijiti, Huerxidan; Zhou, Zheng; Wang, Jianrong; Lu, Wenxia; Zhu, Rong; Yang, Jing; Zhang, Huawei; Yin, Qin; Wang, Chengfen; Zhou, Yuqing; Lu, Jie; Zhou, Yingqun; Guo, Chuanyong

    2015-01-01

    Objective Astaxanthin, a potent antioxidant, exhibits a wide range of biological activities, including antioxidant, atherosclerosis and antitumor activities. However, its effect on concanavalin A (ConA)-induced autoimmune hepatitis remains unclear. The aim of this study was to investigate the protective effects of astaxanthin on ConA-induced hepatitis in mice, and to elucidate the mechanisms of regulation. Materials and Methods Autoimmune hepatitis was induced in in Balb/C mice using ConA (25 mg/kg), and astaxanthin was orally administered daily at two doses (20 mg/kg and 40 mg/kg) for 14 days before ConA injection. Levels of serum liver enzymes and the histopathology of inflammatory cytokines and other maker proteins were determined at three time points (2, 8 and 24 h). Primary hepatocytes were pretreated with astaxanthin (80 ?M) in vitro 24 h before stimulation with TNF-? (10 ng/ml). The apoptosis rate and related protein expression were determined 24 h after the administration of TNF-?. Results Astaxanthin attenuated serum liver enzymes and pathological damage by reducing the release of inflammatory factors. It performed anti-apoptotic effects via the descending phosphorylation of Bcl-2 through the down-regulation of the JNK/p-JNK pathway. Conclusion This research firstly expounded that astaxanthin reduced immune liver injury in ConA-induced autoimmune hepatitis. The mode of action appears to be downregulation of JNK/p-JNK-mediated apoptosis and autophagy. PMID:25761053

  20. Estudio de la influencia de la refrigeracion con aire de forma natural e inducida en el comportamiento de instalaciones fotovoltaicas

    NASA Astrophysics Data System (ADS)

    Mazon Hernandez, Rocio

    The aim is to analyse the negative influence of high panel temperatures on electrical production when they are placed on steel roofs of industrial buildings and greenhouse roofs. Different configurations have been tested in order to allow cooling of photovoltaic panels to decrease panel temperature and improve electrical performance. To research this problem two experimental facilities have been built. The first facility includes two panels fixed on a structure. A panel is integrated on a parallel steel plate which does not allow sufficient cooling. Between both surfaces, there is an open air channel in which an air flow is created by the chimney effect thus cooling the panel by natural convection or inducing air, using a fan, by forced convection. The other panel has not any plate underneath it and is used as a referent. The electrical behaviour of the integrated panel has been studied for different air gaps and induced velocities, being also compared with the reference panel. An experimental model was developed to establish correlations which allow determine the panel temperature depending on the influential variables on the cooling ability. This research also analyses the data of a working solar plant, with the same panel model, obtaining the correlations between electrical variables and panel temperature. A comparison with the electrical behaviour in the experimental facility and the solar plant is also presented. The second experimental facility is a replica of a photovoltaic greenhouse. It consists of four photovoltaic panels placed on the plastic roof, providing an open and divergent channel between both surfaces thus creating an air flow by natural convection. This research studies the effect of high temperatures within the greenhouse which is transferred by the roof and thus affects the electrical production. In addition, two air gaps were used and the effect of adding insulating material to the plastic roof was studied. The electrical variables of the panels are analysed to compare and select the best configuration. The presented research provides a deep knowledge of how they work as well as information and results for an improvement in future designs of building integrated photovoltaic systems. Este estudio se centra en analizar la influencia negativa de la temperatura en la produccion electrica de paneles fotovoltaicos al estar emplazados sobre cubierta de acero, como sucede en naves industriales y sobre un invernadero. Se estudian diferentes configuraciones que permitan refrigerar los paneles, reduciendo su temperatura y mejorar su rendimiento. Para abordar este problema, se han construido dos instalaciones experimentales, fieles a plantas solares en funcionamiento. Una instalacion engloba dos paneles fotovoltaicos sobre estructura fija al suelo. Uno de los paneles esta integrado sobre una superficie paralela y metalica. Entre ambas superficies existe un espacio que posibilita circular aire, permitiendo refrigerar el panel por conveccion natural, o conveccion forzada impulsando el aire con un ventilador. El otro panel, libre por su cara posterior y se ha considerado de referencia. Se ha estudiado el comportamiento del panel integrado sobre cubierta para diferentes secciones de aire y velocidades inducidas, comparandolo con el panel de referencia. Se ha desarrollado un modelo experimental que nos permite determinar la temperatura del panel en funcion de las variables que influyen en su refrigeracion. Adicionalmente, se han analizado los datos de una planta solar en funcionamiento, con paneles de igual caracteristicas, obteniendo correlaciones entre la temperatura del panel y las variables electricas y comparandolos con las obtenidas en la instalacion experimental. La segunda instalacion experimental reproduce parte de una instalacion solar sobre un invernadero, formada por cuatro paneles fotovoltaicos colocados sobre el plastico del invernadero, existiendo un canal divergente entre ambas superficies. Se estudia la influencia de las altas temperaturas en el interior del invernadero sobre la produccion electric

  1. ON EFFECT OF HAZARD MAP ON CONS CIOUSNESS OF FLOOD DISASTER PREVENSION OF RESIDENTS WHO EXPERIENCED FLOOD RECENTLY

    NASA Astrophysics Data System (ADS)

    Asai, Koji; Koga, Syota; Sakakibara, Hiroyuki

    In this paper, the effect of the flood hazard map distributed to the residents who experienced flood disasters recently and an effective method for improving consciousness of flood di saster prevention are discussed. The questionnaire surveys were conducted on the residents living in the middle basin of the Nishiki River, Iwakuni city, Yamaguchi Prefecture, before and after the distribution of the hazard map. It is found from this investigation that "knowledge", "att achment", and "crisis", are the main factors in the psychological process related to the flood prevention behavior. The effect of the distribution of the hazard map is judged from the probability of the flood prevention behavior. In addition, it is also found that "knowledge", "flood experiment of T0514", "crisis", "eff ectiveness", "load", and "easy reading of the hazard map", are keys to improve the cons ciousness of flood di saster prevention.

  2. The role of the HyCon design-support tool in elevating hybrid concrete as a design option for structural frames

    Microsoft Academic Search

    Martin Sexton; Jack Goulding; Xiaonan Zhang; Mike Kagioglou; Ghassan Aouad; Rachel Cooper; Peter Barrett

    2005-01-01

    Purpose – The purpose of this paper is to identify interdependent barriers to the search and selection of new technologies by design engineers at industry, organisation and individual levels. A “proof of concept” HyCon tool is presented to demonstrate the role of information technology design support tools in supporting designers to overcome these inhibitors, in this case for hybrid concrete,

  3. AbstractThe Kern River Gas Transmission pipeline was con-structed in 1991 to supply natural gas to be used in the thermally

    E-print Network

    94 Abstract­The Kern River Gas Transmission pipeline was con- structed in 1991 to supply natural plants were found in the 11 seeded plots. The Kern River Gas Transmission pipeline (KRGT) was constructed California. The pipeline route extended from a point near Opal, Wyoming, through Utah and Nevada to Daggett

  4. EECE Department Seminar After completing a BS degree in Chemistry from Florida State University, David joined Dow in 1981. He con-

    E-print Network

    Subramanian, Venkat

    : elementary reaction based kinetic modeling, computational fluid dynamics, and bifurcation analysis. In his University, David joined Dow in 1981. He con- tributed to the development of a wide variety of process in Corporate R&D labs including Reaction Engineering, Fluid Me- chanics and Mixing, Modeling, and Materials

  5. Texas A&M AgriLife Extension Service Cmo prevenir el asma6 Si el asma de su nio empeora con emociones intensas,

    E-print Network

    Texas A&M AgriLife Extension Service Cómo prevenir el asma6 Si el asma de su niño empeora con contra el asma no controlan bien los ataques durante estos periodos emotivos, háblele a su pediatra sobre cabello pueden desencadenar un ataque de asma. Medidas de control incluyen: Cuando deba usar productos

  6. Kurt J. Koester To obtain a position that allows me to use my skills and knowledge in materials science to con-

    E-print Network

    Ritchie, Robert

    in materials science to con- duct research and develop new products and technologies. EDUCATION: 2003-2007 University of California, Berkeley Berkeley, CA Doctor of Philosophy, Engineering, Materials Science and Engineering Minors: Bioengineering and Business Administration Master of Engineering, Materials Science

  7. AVISO EN CONTRA DE ACTOS DISCRIMINATORIOS De conformidad con la Ley de Derechos Humanos del Distrito de Columbia (D.C.) de 1977, segn enmendada,

    E-print Network

    Weaver, Harold A. "Hal"

    AVISO EN CONTRA DE ACTOS DISCRIMINATORIOS De conformidad con la Ley de Derechos Humanos del a medidas disciplinarias. La Ley de Derechos Humanos del Distrito de Columbia (D.C.), Sección 2-1402.31(a discriminar: "Negarle a una persona, de forma directa o indirecta, el derecho a disfrutar a plenitud y

  8. Departamento de Disciplinas Econmicas y Financieras El Departamento de Disciplinas Econmicas y Financieras, con sede en la Facultad de Derecho de la Universidad

    E-print Network

    Escolano, Francisco

    Financieras, con sede en la Facultad de Derecho de la Universidad de Alicante, está compuesto por el área de conocimiento de Derecho Financiero y Tributario que centra su actividad en las facultades de Derecho, Ciencias: Estudios de 1er y 2º Ciclo (a extinguir) Licenciatura en Derecho. Licenciatura Derecho-ADE (DADE

  9. BANDO DI CONCORSO PER L'ASSEGNAZIONE DI N.7 POSTI (DI CUI N.5 CON BORSA DI STUDIO) PER LA FREQUENZA DI CORSI DI LINGUA, LETTERATURA E

    E-print Network

    Guidoni, Leonardo

    DI CORSI DI LINGUA, LETTERATURA E CULTURA RUSSA PRESSO L'UNIVERSITA' STATALE "M. LOMONOSOV" DI MOSCA superato l'esame di lingua russa del primo anno da 12 CFU con votazione non inferiore a 25/30; · · essere studenti di lingua madre russa o di altri paesi che facevano parte dell'Unione Sovietica. ART. 3 ­ La

  10. Discurso de Orden con motivo de la Celebración del XXX Aniversario de la Facultad de Economía de la Universidad de Los Andes

    Microsoft Academic Search

    Armando Alarcón Fernández

    1988-01-01

    Estamos aquí al abrigo de este sobrio y glorioso recinto, póstumo vestigio de las candelas federales, con la venia de esta audiencia, luminosa expresión del pueblo en sus dos más genuinas representaciones: la Asamblea Legislativa y el Consejo de esta prócera ciudad de Mérida. Nos hemos congregado para hacer memoria del acto académico mediante el cual fue creada la Facultad

  11. ConSoil 2005 -Abstract form Title of abstract Alcohol Flushing: Parameter Estimation for a cost efficient in-situ remediation

    E-print Network

    Cirpka, Olaf Arie

    is necessary to counteract gravitatinal forces. The change of the interfacial tension as a function of alcoholConSoil 2005 - Abstract form Title of abstract Alcohol Flushing: Parameter Estimation for a cost.greiner@iws.uni-stuttgart.de Phone +49 - 711 / 685 4602 Fax +49 - 711 / 685 7020 Topics: Alcohol flushing, in-situ remediation

  12. Synthesis, growth, structural, spectral, thermal, chemical etching, linear and nonlinear optical and mechanical studies of an organic single crystal 4-chloro 4-nitrostilbene (CONS): a potential NLO material.

    PubMed

    Dinakaran, Paul M; Kalainathan, S

    2013-07-01

    4-Chloro 4-nitrostilbene (CONS) a new organic nonlinear optical material has been synthesized. Employing slow evaporation method, good optical quality single crystals (dimensions up to 6×2×3 mm(3)) have been grown using ethyl methyl ketone (EMK) as a solvent. The grown crystals have been subjected to various characterizations such as single crystal X-ray diffraction, powder XRD, Fourier Transform Infrared spectroscopy (FTIR), proton NMR, solid UV absorption, SHG studies. Single crystal X-ray diffraction reveals that the crystal system belongs to monoclinic with noncentrosymmetric space group P21. The UV-Vis absorption spectrum has been recorded and found that the cut off wavelength is 380 nm. Functional groups and the structure of the title compound have been confirmed by FTIR and (1)H NMR spectroscopic analyses respectively. Molecular mass of the CONS confirmed by the high resolution mass spectral analysis .The thermal behavior of the grown crystal has been studied by TG/DTA analysis and it shows the melting point is at 188.66 °C. Dislocations and growth pattern present in the grown crystal revealed by the etching study. The mechanical strength of the CONS crystal has been studied by Vicker's hardness measurement. The SHG efficiency of the grown crystal has been determined by Kurtz and Perry powder test which revealed that the CONS crystal (327 mV) has 15 times greater efficiency than that of KDP (21.7 mV). PMID:23624038

  13. To be presented at the Fourth International Workshop on Virtual Rehabilitation, Catalina Island, CA, September 2005. Usability of the Remote Console (ReCon) for Virtual Reality

    E-print Network

    New Jersey, University of Medicine and Dentistry of

    , September 2005. Usability of the Remote Console (ReCon) for Virtual Reality Telerehabilitation: Formative. Keywords virtual reality, telerehabilitation, physical therapy, formative evaluation, usability engineering for virtual reality telerehabilitation from a host site to a clinic or a home using real-time patient

  14. Evaluación de estimadores no paramétricos de la riqueza de especies. Un ejemplo con aves en áreas verdes de la ciudad de Puebla, México

    Microsoft Academic Search

    J. A. González Oreja; A. A. De la Fuente-Díaz-Ordaz; L. Hernández-Santín; D. Buzo-Franco; C. Bonache-Regidor

    2010-01-01

    Nuestro objetivo fue evaluar el desempeño de estimadores no paramétricos de la riqueza de especies con datos reales. Durante la temporada de cría de 2003 censamos las comunidades de aves en dos áreas verdes de la ciudad de Puebla (México), y obtuvimos las corres¬pondientes curvas de rarefacción, que fueron ajustadas a dos funciones de acumulación de especies no asintóticas y

  15. RELLENAR EN MAYSCULAS A MQUINA, ORDENADOR O CON BOLGRAFO NEGRO Y LETRA DE IMPRENTA. PRESENTAR ORIGINAL Y COPIA. IMPRESO GRATUITO. PROHIBIDA SU VENTA EX 16

    E-print Network

    Geffner, Hector

    ciudadano de la Unión SUPUESTOS DE ACCESO Cónyuge Pareja registrada Descendiente menor de 21 años o incapaz la edad de jubilación con derecho a pensión Trabajador que acceda a la jubilación anticipada

  16. Características psicométricas de las versiones americana y española de la escala TDA-H (Trastorno por Déficit de Atención con Hiperactividad): un estudio comparativo

    Microsoft Academic Search

    Nekane Balluerka; Juana Gómez; William A. Stock; Linda C. Caterino

    2000-01-01

    El presente artículo se centra en el estudio psicométrico de una es- cala para el diagnóstico del Tr a s t o rno por Déficit de Atención con H i p e ra c t ividad en adultos. Dicho tra s t o rno fue descubierto a pri n c i- pios de siglo en la población infantil por un

  17. MODELO MATEMÁTICO PARA EL ORDENAMIENTO DE TAREAS EN UN FLOW-SHOP HÍBRIDO A DOS ETAPAS CON UNA RESTRICCIÓN DE BLOQUEO PARTICULAR

    Microsoft Academic Search

    Sergio Martínez de la Piedra

    2006-01-01

    Este artículo presenta un modelo de programación lineal en números enteros mixtos, el cual, puede ser utilizado para resolver el problema de minimización del tiempo total de paso de un grupo de tareas por un sistema de producción tipo Flow-Shop híbrido a dos etapas sin capacidad de almacenamiento entre ellas y con una nueva restricción de bloqueo, la cual, ha

  18. El viaje a Grecia, o una novela didáctica digital con videoquest, profesor virtual, cuestionarios interactivos ilustrados, blog, wiki y otros recursos TIC

    Microsoft Academic Search

    Manuel Merlo Fernández; Gonzalo Trespaderne Arnaiz

    2010-01-01

    Manuel Merlo Fernández y Gonzalo Trespaderne Arnaiz obtuvieron un Segundo Premio Nacional en el concurso para materiales educativos en soporte electrónico convocado por el Ministerio de Educación a través del CNICE (ahora ITE) y el Premio especial por fomentar la competencia lectora en 2006 con Los caminos de la felicidad. Al año siguiente consiguieron el Primer Premio en el mismo

  19. Animaciones en 3D en tiempo real para las clases de ciencias e ingeniería: Ejemplos desarrollados con el módulo de programación VPython

    Microsoft Academic Search

    Eduardo E. Rodríguez

    RESUMEN: Se describe el uso del módulo de programación VPython para desarrollar animaciones en 3D por computadora para ilustrar temas de interés para las clases. Mostramos la utilidad del uso de animaciones para reforzar las presentaciones de materias como física y matemática, entre otras. Con tales presentaciones se puede innovar en el desarrollo de las clases de ciencias e ingeniería

  20. Decreto n. 368 IL RETTORE VISTO il D.R. n. 4322 in data 12/11/2013, parzialmente modificato con D.R. n. 4571 in data

    E-print Network

    Malerba, Donato

    'art. 7 del DR 4322/2013, in data 3 febbraio 2014; VISTA nota in data 4/2/2014 con cui la candidata CIARDO ROSELLI Giovanna e CIARDO Carmela sono ammesse a sostenere la prova scritta poiché collocate ROSELLI Giovanna e CIARDO Carmela, collocate, rispettivamente, al posto n. 81 e al posto n. 84 della

  1. AC 2011-376: WIRELESS-INTEGRATED EMBEDDED REAL-TIME CON-TROL: A CASE STUDY IN ADOPTING RESOURCES FOR DEVELOP-

    E-print Network

    AC 2011-376: WIRELESS-INTEGRATED EMBEDDED REAL-TIME CON- TROL: A CASE STUDY IN ADOPTING RESOURCES of Engineering. cAmerican Society for Engineering Education, 2011 #12;Wireless-Integrated Embedded Real-Time in areas of control and embedded systems that weaves critical aspects of control systems design with real-time

  2. DESARROLLO Y APLICACIÓN DE LECCIONES DE ESTADÍSTICA EN-LÍNEA CON OBJETOS DE APRENDIZAJE EN UN AMBIENTE UNIVERSITARIO PEDAGOGICAL IMPACT OF CONSTRUCTIVIST LEARNING OBJECTS IN STATISTIC TEACHING

    Microsoft Academic Search

    Javier Organista Sandoval; Gilles Lavigne

    2006-01-01

    Resumen: Se presentan resultados preliminares de una investigación-desarrollo que tuvo el propósito de desarrollar lecciones de Estadística en línea con inserción de objetos de aprendizaje y estimar el efecto sobre el aprendizaje de los alumnos participantes en un ambiente natural universitario. Se utilizaron señalamientos teóricos constructivistas para el desarrollo de las lecciones, para conformarle al estudiante un ambiente en línea

  3. x1 PICTURES INTRODUCTION AND MAIN DATA STRUCTURES* 1. Introduction and main data structures. This is the file pictures.wthat con*

    E-print Network

    van Leeuwen, Marc

    x1 PICTURES INTRODUCTION AND MAIN DATA STRUCTURES* * 1 1. Introduction and main data structures. This is the file pictures.wthat con* *tains the central part to manipulate mathematical "pictures" as defined in [Zel]. That library, which is * *contained in the file pict

  4. Pure Appl. Chem., Vol. 82, No. 12, pp. 22472279, 2010. doi:10.1351/PAC-CON-10-09-04

    E-print Network

    Martin, Jan M.L.

    2247 Pure Appl. Chem., Vol. 82, No. 12, pp. 2247­2279, 2010. doi:10.1351/PAC-CON-10-09-04 © 2010 to the trans form once the UV source is removed. Although this thermal re-isomerization is slow, *Pure Appl

  5. El gasto en salud y su relación con el ingreso, la escolaridad y el tipo de vinculación al sistema general de seguridad social: evidencia para el depa

    Microsoft Academic Search

    Armando Antonio Gil Ospina; Hedmann Alberto Sierra Sierra

    2006-01-01

    El objetivo principal de este trabajo es explicar cómo se relaciona el gasto en salud con el ingreso, la escolaridad y el tipo de afiliación de las personas al sistema general de seguridad social en salud en el departamento del Risaralda. Se realiza una revisión de la literatura que sirve como base teórico-conceptual y se propone, a manera de hipótesis,

  6. Structural, electronic and magnetic properties of ConPt, for M=13, 19, and 55, from first principles

    NASA Astrophysics Data System (ADS)

    Montejano-Carrizales, J. M.; Aguilera-Granja, F.; Goyhenex, C.; Pierron-Bohnes, V.; Morán-López, J. L.

    2014-04-01

    The geometrical structure, chemical ordering, electronic and magnetic properties of ConPt, for M=13, 19, and 55, are investigated, within the framework of the density functional theory as implemented in the SIESTA code. For the exchange and correlation potential, we used the Perdew-Burke-Ernzerhof (PBE) form of the generalized gradient approximation (GGA). We considered the hexagonal, the cubo-octahedral (CO), the centered pentagonal prism (CPP), and the icosahedral (ICO) geometries. We found that the CO, ICO, and CPP structures have similar energies and the lowest energy configuration changes as a function of the Co concentration and cluster size. In most of the cases, around the equiatomic concentration, the Co and Pt atoms form chemically ordered structures, but most often not the L10 structure stable in bulk. We observed that the Pt atoms are segregated to the surface in all the concentration range. A detailed analysis of the dependence of the magnetic moment of the components, and their average, as a function of structure and of chemical composition is reported. A strong polarization of the Pt atoms by the nearest neighbor Co atoms is observed.

  7. Evaluation of GO_CONS_GCF_2_TIM and GOCO01S Geopotential Models in Venezuela and Caribbean Region

    NASA Astrophysics Data System (ADS)

    Orihuela, N. D.; Garcia, A. D.; Tabare, T.; Scientific Team Of Venezuelan; Caribbean Crustal Study From Satellital Data

    2010-12-01

    This paper shows two maps of the magnitude of the surface gravity vector (MSGV) of Venezuela and Caribbean region at 1:500.000 scale in the geographic window between the 0-20 north latitude and 74-58 western longitude (Fig. 1 and Fig. 2), that were generated from GOCE gravity gradients data provided by the European Space Agency (ESA). The maps that are showed come from the combined global gravity field model GOCO01s [GOCO Consortium., 2010] and from the satellite-only global gravity field model GO_CONS_GCF_2_TIM [Pail et al., 2010], both of 224 degree. The DEMs used for the evaluation of the MSGV are: Etopo2v2 [NGDC., 2006] and Etopo1 [Amante and Eakins, 2009] respectively. The data processing was done using: Shm2func [ICGEM., 2007]; Goce User Toolbox [ESA., 2009]; Gravsoft package [Tscherning et al., 1992] and Oasis Montaj (Geosoft). This research shows a review of observed gravity in the main geological provinces of the Venezuela and Caribbean region geography, revealing gravitational features important of the geological structures that are in Venezuelan and Caribbean subsurface.

  8. Aprendiendo con Veronica.

    ERIC Educational Resources Information Center

    McDonald-O'Brien, Pat

    1996-01-01

    Describes how an elementary school literacy specialist worked with and saw the dilemmas, frustrations, and heartaches of a new student from Puerto Rico. Notes that the literacy specialist learned valuable lessons and gained an appreciation for the need to honor and celebrate, engage and instruct all students from all over the globe. (SR)

  9. The Classics, Con Brio

    ERIC Educational Resources Information Center

    Hansen, James

    1978-01-01

    Sponsored by a consortium of 30 American universities, Rome's Intercollegiate Center for Classical Studies offers a year of study to American undergraduate classics majors. Instructors are also American and normally stay only a year; teaching assistants are always ex-students of the center. Extensive field trips are an important part of the…

  10. EthicsConRep

    Cancer.gov

    The authors also gratefully acknowledge the copy editing assistance of Leslie Alter, MPH and Steve Brown. The Ethical Force Program’s initiative on patient-centered communication is funded in part by the American Medical Association Foundation, The California Endowment, the Commonwealth Fund and the Connecticut Health Foundation.

  11. Neo-Conned University

    ERIC Educational Resources Information Center

    Jones, Andee

    2014-01-01

    Censorship, says Australian political theorist John Keane (1991), can "echo within us, take up residence within ourselves, spying on us, a private amanuensis who reminds us never to go too far... It makes us zip our lips, tremble and think twice" (p. 39). It can also make us sick. The author states that this is her argument here: that,…

  12. urban ConAgraculture

    Microsoft Academic Search

    Dale J Luebbert

    2009-01-01

    Current pressures in today’s world caused me to investigate strategies of change in the organization of society to promote a more effi cient existence. Globalization, a movement characterized by the dissemination of economies, ethnicities, media, ideas, technologies, and production; has become today’s reality. The shift from imperialism to globalism has caused a decline in the power and importance of nation

  13. Long-term fertility control in female cats with GonaCon™, a GnRH immunocontraceptive.

    PubMed

    Levy, Julie K; Friary, John A; Miller, Lowell A; Tucker, Sylvia J; Fagerstone, Kathleen A

    2011-11-01

    The uncontrolled reproduction of free-roaming feral cats contributes to overpopulation and associated concerns regarding their welfare and impact on public health and the environment. Nonsurgical fertility control that could be administered to feral cats in the field would be a powerful tool for cat population control. The objective was to test the efficacy and duration of activity of a single-dose GnRH immunocontraceptive vaccine (GonaCon™) on the fertility of adult female laboratory cats. Vaccinated cats (n = 15) received a single injection of vaccine containing a GnRH-KLH conjugate (200 ?g) emulsified in a mycobacterial and oil adjuvant on study Day 0. Sham-treated cats (n = 5) received a single injection containing all vaccine components except the GnRH-KLH conjugate. A breeding trial started on study Day 120. Vaccinated cats had a longer time to conception (median 39.7 mo) compared to sham-treated cats (4.4 mo; P < 0.001). A total of 93% of vaccinated cats remained infertile for the first year following vaccination, whereas 73, 53, and 40% were infertile for 2, 3, and 4 y, respectively. At study termination (5 y after a single GnRH vaccine was administered), four cats (27%) remained infertile. The GnRH antibody titers declined more rapidly in short-term responding cats with < 2 y of infertility (n = 4), compared to long-term responding cats that experienced fertility control for >2 y (n = 11) (P < 0.05). Non-painful but persistent late-onset granulomatous injection site masses appeared 2 y after initial vaccination in five cats. We concluded that GnRH immunocontraception is an ideal candidate for further development for feral cat control. PMID:21835455

  14. Accessory cell function in the Con A response: role of Ia-positive and Ia-negative accessory cells.

    PubMed

    Bekoff, M; Kakiuchi, T; Grey, H M

    1985-03-01

    We have examined the role of Ia-positive and Ia-negative accessory cells (AC) and soluble factors in Con A-stimulated murine T cell activation. Supernatant fluids containing interleukin 1 (IL 1) derived from the P388D1 macrophage cell line and from a lipopolysaccharide (LPS)-stimulated macrophage hybridoma provided only partial reconstitution of the response of purified T cells (18 to 27%). The complete reconstitution obtained with gamma-irradiated spleen cells or LPS-activated B cells was inhibited by approximately 60 to 77% when anti-Ia antibody was included in the culture. Despite this apparent involvement of Ia+ spleen AC, Ia-negative L cell AC could also reconstitute the response of both Class I-restricted Lyt-2+ T cells and Class II-restricted L3T4+ T cells. When the Ia-negative AC were employed, the L3T4 antigen on L3T4+ T cells played a critical role because addition of anti-L3T4 antibody to the culture inhibited the response by 85 to 90%. In contrast, anti-L3T4 did not inhibit the response in the presence of spleen AC. These results suggest that the molecules involved in T cell-AC interactions may vary depending on the AC source. Moreover, at least one of the putative target ligands for L3T4 presumably is not Ia, because anti-L3T4 inhibited T cell stimulation when Ia-negative AC were used. PMID:3881521

  15. L'assemblea dei docenti e del personale dell'Ateneo genovese, riunita nell'Aula magna il 23 ottobre 2008, con la partecipazione del Rettore magnifico uscente e di

    E-print Network

    Mascardi, Viviana

    L'assemblea dei docenti e del personale dell'Ateneo genovese, riunita nell'Aula magna il 23 ottobre 2008, con la partecipazione del Rettore magnifico uscente e di quello entrante, dei rappresentanti lamentele sul carattere menzognero dei media e con moniti sinistri ai responsabili dell'informazione; CHIEDE

  16. Misurare il vissuto depressivo con uno strumento self-report: il Differentieller Depressions Fragebogen (DDF) Measuring the depressive experience with a self-report measure: the Differentieller Depressions Fragebogen (DDF)

    Microsoft Academic Search

    M. Giannini; A. Gori; C. Bocali; P. Steck

    2008-01-01

    Summary Background This study aims to test the psychometric properties of the Italian version of a ques- tionnaire developed to assess different aspects of depression: the Differentieller Depressions Fragebogen (DDF). The DDF is a self-report questionnaire con- sisting of 76 dichotomous (true\\/false) items distributed over six scales that con- sent a rapid and accurate assessment of depression. The dimensions of

  17. The Protective Effect of Intrasplenic Transplantation of Ad-IL-18BP/IL-4 Gene-Modified Fetal Hepatocytes on ConA-Induced Hepatitis in Mice

    PubMed Central

    Xu, Chenhuai; Hong, Bo; Xu, Wanhong; Shen, Ling; Jin, Changzhong; Wu, Zhigang; Tong, Xiangmin; Yao, Hangping

    2013-01-01

    Background Concanavalin A (ConA)-induced hepatitis is an experimental murine model mirroring the pathology of human autoimmune hepatitis. Aim To investigate the effects of intrasplenically transplanted fetal hepatocytes (BNL.CL2) transfected with recombinant adenovirus vector expressing the IL-18 binding protein (IL-18BP) and IL-4 fusion protein on ConA-induced hepatitis in mice. Methods Ad-IL-18BP/IL-4 was used to infect BNL.CL2 cells. IL-4 and IL-18BP fusion protein expression were detected by ELISA and Western blotting. BNL.CL2 cells infected with Ad-IL-18BP/IL-4 were intrasplenically transplanted into mice. After 10 days, mice were injected with ConA (15 mg/kg), and sacrificed 18 hours later. Liver injury was assessed by serum transaminase and liver histology. TNF-?, IL-18, IL-4, IL-10, IL-12p70 and monocyte-chemoattracting protein (MCP)-1 levels in serum and liver homogenates were detected by ELISA. Signaling molecules in liver homogenates were analyzed by Western blotting. Results Ad-IL-18BP/IL-4 effectively expressed the IL-18BP/IL-4 fusion protein for more than 14 days in BNL.CL12 cells. Treatment of mice with Ad-IL-18BP/IL-4-BNL.CL2 before ConA injection significantly reduced the elevated plasma levels of transaminases compared with ConA control groups. TNF-?, IL-18, IL-12p70 and MCP-1 levels in serum and liver homogenates from mice transplanted with Ad-IL-18BP/IL-4-BNL.CL2 were lower and IL-4 and IL-10 levels were higher than control groups. Phosphorylation levels of NF-?B p65, AKT, p38 and JNK1/2 in liver homogenates were markedly suppressed by Ad-IL-18BP/IL-4. Conclusions Ad-IL-18BP/IL-4 was effectively transfected into mouse BNL.CL2 cells. Intrasplenic transplantation of Ad-IL-18BP/IL-4-BNL.CL12 cells alleviated the severity of inflammation in ConA-induced experimental hepatitis and provides a useful basis for the targeted gene therapy of liver disease. PMID:23516562

  18. Effects of NH3 flow rate on the epitaxial growth of CoSi2 thin film using a CoN x interlayer deposited by MOCVD

    NASA Astrophysics Data System (ADS)

    Lee, Seung Ryul; Ahn, Byung Tae; Kang, Bo Soo

    2015-06-01

    A uniform epitaxial CoSi2 layer could be grown on a Si(100) substrate by deposition of a CoN x interlayer followed by an in situ annealing process. The amorphous Si-N layer which is formed at the CoN x /Si interface plays a role in inhibiting excessive Co incorporation into Si layer and consequently enhancing the epitaxial growth of CoSi2 layer. However, the Si-N layer also limits the growth of thick CoSi2 layer. Therefore, the thickness of the amorphous Si-N layer is an important factor for the epitaxial growth of the CoSi2 layer with uniform structure and low sheet resistance.

  19. Methanol extract of Biophytum sensitivum alters the cytokine profile and inhibits iNOS and COX-2 expression in LPS/Con A stimulated macrophages.

    PubMed

    Guruvayoorappan, Chandrasekharan; Kuttan, Girija

    2008-01-01

    Biophytum sensitivum has been used in traditional folk medicine to treat numerous diseases. The molecular mechanism of B. sensitivum pharmacological and biochemical actions of macrophages in inflammation has not been clearly elucidated. We examined how the methanol extract of B. sensitivum regulates the production of interleukin (IL)-1beta, tumor necrosis factor (TNF)-alpha, IL-6, and nitric oxide (NO) in vitro and in vivo. The extract inhibits the production of NO and proinflammatory cytokines in lipopolysaccharide (LPS) or Concanavalin (Con) A-stimulated primary macrophages. In vitro L929 bioassay revealed the inhibition of TNF-alpha production by B. sensitivum treatment. Moreover, the extract could suppress the inducible nitric oxide synthase and cyclo-oxygenase-2 mRNA expression in LPS or Con A-stimulated macrophages. These findings provide evidence that B. sensitivum possesses potential anti-inflammatory activity and may be beneficial for the treatment of endotoxin shock or sepsis. PMID:18161516

  20. Li storage and impedance spectroscopy studies on Co3O4, CoO, and CoN for Li-ion batteries.

    PubMed

    Reddy, M V; Prithvi, Gundlapalli; Loh, Kian Ping; Chowdari, B V R

    2014-01-01

    The compounds, CoN, CoO, and Co3O4 were prepared in the form of nano-rod/particles and we investigated the Li-cycling properties, and their use as an anode material. The urea combustion method, nitridation, and carbothermal reduction methods were adopted to prepare Co3O4, CoN, and CoO, respectively. X-ray diffraction (XRD), scanning electron microscope (SEM), transmission electron microscope (TEM), and the Brunauer-Emmett-Teller (BET) surface and density methods were used to characterise the materials. Cyclic voltammetry (CV) was performed and galvanostatic cycling tests were also conducted up to 60-70 cycles. The observed reversible capacity of all compounds is of the increasing order CoO, Co3O4, CoN and all compounds showed negligible capacity fading. CoO allows for Li2O and Co metal to form during the discharge cycle, allowing for a high theoretical capacity of 715 mA h g(-1). Co3O4 allows for 4 Li2O and 3Co to form, and has a theoretical capacity of 890 mAhg(-1). CoN is the best anode material of the three because the nitrogen allows for Li3N and Co to form, resulting in an even higher theoretical capacity of 1100 mAhg(-1) due to the Li3N and Co metal formation. Irrespective of morphology the charge profiles of all three compounds showed a major plateaux ~2.0 V vs. Li and potential values are almost unchanged irrespective of crystal structure. Electrochemical impedance spectroscopy (EIS) was performed to understand variation resistance and capacitance values. PMID:24325322

  1. EDIFICI E CULTI Di un altro edificio a carattere pubblico si ha un possibile indizio nel decretoA1, con la menzione della concessione

    E-print Network

    Abbondandolo, Alberto

    essere dotata, e che è probabilmente da localizzare nei pressi dell'agora e dei principali edifici città siceliota: planimetria dell'agora di Iaitas con i due bouleuteria (fine del IV sec. a.C. e ultimo.C.). Pianta del bouleuterion di Segesta (fine II a.C.). l'area dell'agora (cf. ENTELLA: LA CITT�) e che si

  2. 98 VHDL: LENGUAJE PARA S INTESIS Y MODELADO DE CIRCUITOS c En una funcion, y siempre con caracter opcional e informativo, existe la posibilidad

    E-print Network

    Valencia, Universidad de

    98 VHDL: LENGUAJE PARA S â?? INTESIS Y MODELADO DE CIRCUITOS c RA­MA En una funciâ??on, y siempre con carâ??acter opcional e informativo, existe la posibilidad de declararla como PURE o IMPURE. Un funciâ??on pura es una funciâ??on que devuelve siem­ pre el mismo valor para unos parâ??ametros de entrada dados. Una

  3. 1.0 What is Statistics? 1.1 What is Mathematical Statistics? Random Data Basic Ideas in Statistics 1.2 Fundamental Con Mathematical Statistics

    E-print Network

    Zhang, Li-Xin

    §1.0 What is Statistics? §1.1 What is Mathematical Statistics? Random Data Basic Ideas in Statistics §1.2 Fundamental Con Mathematical Statistics Zhang, Lixin and Dai, Jialing Course Website: www.math.zju.edu.cn/zlx/teaching.htm #12;§1.0 What is Statistics? §1.1 What is Mathematical Statistics? Random Data Basic Ideas

  4. HOW TO geT TOTHe MANOA &OOK5TORe PURIN9 THe CAMPU5 ceNTeR CON5TRUCTION.

    E-print Network

    HOW TO geT TOTHe MANOA &OOK5TORe PURIN9 THe CAMPU5 ceNTeR CON5TRUCTION. TAICES TtiES 9TAIRWAY"'U"llH;- (., ntfT ACCE:%I~L.E! F~OMF,,~ ·.w, THE: ~E:CONP FL.OO~ OF CAMPU~ CE:NTE:~ VIA THE: ~TAI~WAY LYOU CAN AL.~O E:NTE:~ Sc'd~,ho :\\I.uliott THE: G~OUNP L.E:VE:L. E!NT~ANCE: TH~OUGH THE: TE:MPO~A~Y WAL

  5. 15-Deoxy-?12,14-prostaglandin J2 Reduces Liver Impairment in a Model of ConA-Induced Acute Hepatic Inflammation by Activation of PPAR? and Reduction in NF-?B Activity

    PubMed Central

    Chen, Kan; Li, Jingjing; Wang, Junshan; Xia, Yujing; Dai, Weiqi; Wang, Fan; Shen, Miao; Cheng, Ping; Zhang, Yan; Wang, Chengfen; Yang, Jing; Zhu, Rong; Zhang, Huawei; Zheng, Yuanyuan; Lu, Jie; Fan, Zhuoyi; Zhou, Yingqun; Guo, Chuanyong

    2014-01-01

    Objective. 15-Deoxy-?12,14-prostaglandin J2 (15d-PGJ2) reduces inflammation and has been identified as an anti-inflammatory prostaglandin in numerous animal models. In this study, we investigated both effects of 15d-PGJ2 and its protection mechanism in concanavalin A- (ConA-) induced autoimmune hepatitis in mice. Materials and Methods. In vivo, Balb/C mice were injected with ConA (25?mg/kg) to induce acute autoimmune hepatitis, and 15d-PGJ2 (10??g or 25??g) was administered 1?h before the ConA injection. The histological grade, proinflammatory cytokine levels, and NF-?B and PPAR? activity were determined 6, 12, and 24?h after the ConA injection. In vitro, LO2 cells and RAW264.7 cells were pretreated with 15d-PGJ2 (2??M) 1?h before the stimulation with ConA (30??g/mL). The NF-?B and PPAR? activity were determined 30?min after the ConA administration. Results. Pretreatment with 15d-PGJ2 reduced the pathological effects of ConA-induced autoimmune hepatitis and significantly reduced the levels of cytokines after injection. 15d-PGJ2 activated PPAR?, blocked the degradation of I?B?, and inhibited the translocation of NF-?B into the nucleus. Conclusion. These results indicate that 15d-PGJ2 protects against ConA-induced autoimmune hepatitis by reducing proinflammatory cytokines. This reduction in inflammation may correlate with the activation of PPAR? and the reduction in NF-?B activity. PMID:25120564

  6. Clinico-pathological manifestations of variant late infantile neuronal ceroid lipofuscinosis (vLINCL) caused by a novel mutation in MFSD8 gene.

    PubMed

    Mandel, Hanna; Cohen Katsanelson, Ksenya; Khayat, Morad; Chervinsky, Ilana; Vladovski, Eugene; Iancu, Theodor C; Indelman, Margarita; Horovitz, Yoseph; Sprecher, Eli; Shalev, Stavit A; Spiegel, Ronen

    2014-01-01

    Neuronal ceroid lipofuscinosis (NCL) refers to a growing heterogeneous group of neurodegenerative disorders characterized by lysosomal accumulation of abnormal autofluorescent material. NCLs are traditionally classified clinically according to their age of onset. Variable late infantile NCL (vLINCL) is the most genetically heterogeneous subtype as it has been shown to be caused by mutations in at least six genes. We report on 5 patients of a consanguineous family who presented in early childhood with intractable seizures, severe cognitive and motor decline, behavioral impairment and progressive retinal degeneration. Disease course was severe; all patients were in a vegetative state by the second decade of life, and eventually die prematurely (except in one case). Ultrastructural studies of brain and rectal mucosa disclosed accumulation of storage material in various patterns including fingerprint, curvilinear, and granular osmiophilic deposits consistent with the diagnosis of NCL. Brain pathologic features from a living patient are first reported here and shed light on disease progression and pathogenesis. Using a combination of whole genome autozygosity mapping and candidate gene direct sequencing, we identified a mutation in MFSD8, c.472G>A (p.Gly158Ser), which was found to segregate with the disease phenotype in the family. This study underscores the importance of a combined clinic-molecular workup in NCLs and other neurodegenerative conditions. PMID:25270050

  7. Comparison of matrix metalloproteinase-3 and tissue inhibitor of matrix metalloproteinase-1 levels in gingival crevicular fluid in periodontal health, disease and after treatment: A clinico biochemical study

    PubMed Central

    Kumar, P. Mohan; Reddy, N. Ravindra; Deepa, A.; Babu, D. S. Madhu; Kumar, A. Kishore; Chavan, Vinay

    2013-01-01

    Background: Considering the role of matrix metalloproteinase-3 (MMP-3) and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in the pathogenesis of periodontitis, the present study is to estimate the levels of MMP-3 and TIMP-1 in gingival crevicular fluid (GCF) in periodontal health, disease and to evaluate the effect of periodontal therapy on MMP-3 and TIMP-1 concentrations in GCF. Materials and Methods: A periodontal examination and collection of GCF by extra-crevicular method was performed in 30 subjects selected randomly and categorized into 3 groups. Group I consists of 10 subjects Group II consists of 20 patients and Group III consists of 20 patients of Group II. Non surgical periodontal therapy was performed, and GCF was collected after 8 weeks from the same site of 20 chronic periodontitis patients who are considered as Group III. MMP-?3 and TIMP-1 levels were estimated in GCF-samples by using enzyme-linked immunosorbent assay. The findings were analyzed using the software and descriptive statistical methods such as Mann-?Whitney U-test and Kruskal-Wallis test. P value < 0.001 was considered significant. Results: MMP-3 and TIMP-1 was detected in all samples. Highest mean MMP-3 concentrations in GCF were obtained for Group II (7.490 ng/ml) while the lowest concentrations were seen in Group I (0.344 ng/ml) and Group III (2.129 ng/ml). This suggests that MMP-3 levels in GCF increases proportionally with the progression of periodontal disease and decreases after treatment. Lowest mean TIMP-1 concentrations in GCF were obtained for Group-II (1.592 ng/ml), while the highest concentrations were seen in Group-I (8.78 ng/ml) and Group-III (6.40 ng/ml). This suggests that TIMP-1 levels in GCF decreases proportionally with progression of periodontal disease and increases after treatment. Conclusion: There is a substantial increase in the concentrations of MMP-3 and decrease in TIMP-1 as periodontal disease progress. Since MMP-3 and TIMP-1 levels in GCF are positively correlated with gingival index, probing pocket depth, and clinical attachment loss, MMP-3, and TIMP-1 may be considered as a Novel Biomarkers in periodontal disease. However, controlled, longitudinal studies are needed to confirm this possibility. PMID:24130576

  8. Clinico-Pathological Features of Newcastle Disease in Japanese Quails (Coturnix coturnix japonica) Infected with Newcastle Disease Virus Kudu 113 Strain

    Microsoft Academic Search

    Sunday Blessing Oladele; Ishiaku Enoch; O. J. Ibu

    2008-01-01

    3 Abstract: Experiments were performed to determine whether Japanese quails (Coturnix coturnix japonica) are susceptible to Newcastle disease virus (NDV) Kudu 113 strain. In the experimental trials, a total 119, six weeks old Japanese quails were administered varying doses of the virus, ranging from 0.1 ml to 0.3 ml intramuscularly (im) and per os (po). The uninfected control quails were

  9. A comparative clinico-pathologic investigation of the effect of chloroquine phosphate on the eyes and brain of several animal species 

    E-print Network

    Dukes, Thomas William

    1969-01-01

    and stained with H&E. Sudan Black and periodic acid Schiff were used to stain frozen sections and paraffin sections of the chicken brains. Cresyl echt violet, luxol fast blue, oil red 0, alcian blue, and nile blue sulphate 4 stains were also used... was present in the nonfoamy areas of the cytoplasm but ab- sent where the cytoplasm was foamy. The foamy areas were not stained by the P. A. S. reaction, luxol fast blue, alcian blue, cresyl-echt violet, and nile blue sulphate stains. Affected neurons were...

  10. Clinico- pathological profile and course of malignant pleural effusion in a tertiary care teaching hospital in western U.P. with special reference to lung cancer

    PubMed Central

    Agrawal, Anurag; Tandon, Rajeev; Singh, Lalit; Chawla, Aakanksha

    2015-01-01

    Background: Malignant pleural effusion is a major clinical problem associated with primary and metastatic pleural malignancies. Pleural effusions from an unknown primary are responsible for 7-15% of all malignant pleural effusions. Presence of malignant pleural effusion puts the patient in advanced stage and renders the prognosis as poor. Aim: In this study we intend to find out the incidence of malignant pleural effusion, its aetiology and clinical course in patients attending a tertiary care teaching hospital. Results: A total of 308 patients were included in this study. A majority of the patients were in age group 50- 70 years (median age = 58.8 years; range 32- 85 yrs). Male to female ratio was 2.5:1. The major primary cancers were lung cancer (135), lymphoma (40), breast cancer (36), female genital tract (30) gastrointestinal (21), and others (8). In 38 cases primary remained unknown. The yields of pleural fluid cytology, blind pleural biopsy, CT/USG guided pleural biopsy and thoracoscopy were 60%, 49%, 76% and 91% respectively. Chemical pleurodesis yielded complete response in 80%, incomplete response in another 13% patients. Only 136 (44%) cases could be followed up for minimum of 6 months. A majority of them (95, 69.85%) died. Conclusion: We conclude that malignant pleural effusion is a commonly misdiagnosed medical entity. Lung cancer is the commonest cause. Despite all efforts, in about 15% of the cases, primary remains undiagnosed. Thoracoscopy/pleuroscopy is a cost effective measure for diagnosis. Chemical pleurodesis provides expected results but mortality remains high. PMID:26180380

  11. Extranodal Non-Hodgkin's Lymphomas - A Retrospective Review of ClinicoPathologic Features and Outcomes in Comparison with Nodal Non-Hodgkin's Lymphomas

    Microsoft Academic Search

    Amar Lal; Yasmin Bhurgri; Irfan Vaziri; Nida B. Rizvi; Aliyah Sadaf; Saba Sartajuddin; Mohammed Islam; Pawan Kumar; Salman Adil; Ghulam Nabi Kakepoto; Nehal Masood; Mohammed Khurshed; Amyn Alidina

    2008-01-01

    Objective: The primary objective of this study was to analyze the anatomic distribution, clinical features and outcome of Diffuse large B-cell lymphoma (DLBCL) patients according to the primary site (extranodal vs. nodal) with applicability of International Prognostic Index (IPI). Methodology: A retrospective review (1988 to 2004) of 557 cases of DLBC. Results: The median age was 48.7 ± 15.3 years;

  12. The expression of gene transcripts of telomere-associated genes in human breast cancer: correlation with clinico-pathological parameters and clinical outcome

    Microsoft Academic Search

    Mohamed Salhab; Wen G. Jiang; Robert F. Newbold; Kefah Mokbel

    2008-01-01

    Background: Telomerase is a ribonucleoprotein enzyme that synthesises telomeres in human germ cells, embryogenesis and in cancer, maintaining\\u000a chromosomal length, stability and cellular immortality. The hTERT gene is the rate-limiting determinant of telomerase reactivation\\u000a during immortalization and malignant transformation. Telomeric DNA-binding proteins have been attracting increasing interest\\u000a due to their essential role in the regulation of telomeric DNA length and

  13. A Study on the Clinico-Epidemiological Profile and the Outcome of Snake Bite Victims in a Tertiary Care Centre in Southern India

    PubMed Central

    B.R., Halesha; L., Harshavardhan; A J., Lokesh; P.K., Channaveerappa; K.B, Venkatesh

    2013-01-01

    Background: Snake bite is a common medical emergency and an occupational hazard, more so in tropical India, where farming is a major source of employment. The available data on the epidemiology of snake bite from the Indian subcontinent are sparse. Snake bite is a neglected disease that afflicts the most impoverished inhabitants of the rural areas in the tropical developing countries. Aims: This study was carried out to describe the epidemiology, arrival delays, clinical features, complications, and the outcome of snakebites which were seen in a tertiary care hospital of southern India. Setting: Sri Chamarajendra District Hospital which is attached to the Hassan Institute of Medical Sciences, Hassan, Karnataka, India. Study Design: A record–based, retrospective, descriptive study. Materials and Methods: One hundred eighty patients of snake bite were studied from January 2010 to December 2011. The data on the demographic factors, clinical features and complications, details of the treatment which was received and the outcome of the snake bite victims were recorded and analyzed. Results: Among a total 180 cases of snake bite, there were 108 cases of viper bite which presented with haematotoxic manifestations and 74 elapid bites had neuroparalytic manifestations. The victims were predominantly males (60.5%) and they were aged 20-40 years. A majority of the victims are from the rural areas (81.1%) and most of the bites occurred during the day time (70.5%), mainly on the lower limbs (67.2%). The highest number of cases occurred during July- September. Most of the victims were farmers (54.4%) and plantation workers (30.5%), which suggested that snake bite was an occupational hazard. A reaction to the ASV was noted in 12.7% of the patients and the mortality rate in our study was 3.8%. Conclusion: In the tropics, snake bite is a rural and an occupational hazard among farmers, plantation workers, herders and hunters. Regular public health programmes regarding the prevention, pre –hospital management (first aid) and the importance of the early transfer to the hospital should be emphasized. PMID:23450135

  14. [The clinico-epidemiological aspects of the tuberculosis incidence in the Gypsy population in the 4th and 5th districts of the city of Bucharest].

    PubMed

    Dediu, I; Tig?u, M; Palaghianu, L; Plopeanu, D; Didilescu, C

    2000-01-01

    The study analyzes 126 gypsy patients, aged over 15, registered with tuberculosis over 2 years (1996-1997) in two districts of Bucharest (IV and V). The risk of the disease was twice larger in men than women, the age group most affected was 30-49. For lung tuberculosis, bacteriological confirmation was 85%. 83% of bacteriological confirmed cases were smear positive, suggesting the high contagious risk at the time of the discovery. Only 48% favorable results after chemotherapy are partially explained by the low level of education for health in this population, high rate of associated diseases (66.7%) etc. Being a group with high risk for tuberculosis, the gypsy population needs targeted measures for discovering the disease and prophylaxis. PMID:10916411

  15. In vivo optical imaging of human retinal capillary networks using speckle variance optical coherence tomography with quantitative clinico-histological correlation.

    PubMed

    Chan, Geoffrey; Balaratnasingam, Chandrakumar; Xu, Jing; Mammo, Zaid; Han, Sherry; Mackenzie, Paul; Merkur, Andrew; Kirker, Andrew; Albiani, David; Sarunic, Marinko V; Yu, Dao-Yi

    2015-07-01

    Retinal capillary networks are critically linked to neuronal health and disease. The ability to perform accurate in vivo examination of human retinal capillary networks is therefore valuable for studying mechanisms that govern retinal homeostasis and retinal vascular diseases. Speckle variance optical coherence tomography (svOCT) is a non-invasive imaging technique that has the capacity to provide angiographic information about the retinal circulation. The application of this technology for studying human retinal capillary networks however has not been validated in a quantifiable manner. We use a custom-built svOCT device to qualitatively and quantitatively study the various capillary networks in the human perifovea. Capillary networks corresponding to the nerve fibre layer (NFL), the retinal ganglion cell/superficial inner plexiform layer (RGC/sIPL), the deep inner plexiform layer/superficial inner nuclear layer (dIPL/sINL) and the deep inner nuclear layer (dINL) are imaged in 9 normal human subjects. Measurements of capillary diameter and capillary density are made from each of these networks and results are compared to post-mortem histological data acquired with confocal scanning laser microscopy. Additionally, retinal capillary measurements from high-resolution fundus fluorescein angiogram (FA) are directly compared with svOCT images from 6 eyes. We demonstrate that svOCT images of capillary networks are morphologically comparable to microscopic images of histological specimens. Similar to histological images in svOCT images, the capillaries in the NFL network run parallel to the direction of RGC axons while capillaries in the dINL network comprise a planar configuration with multiple closed loops. Capillaries in remaining networks are convoluted with a complex three-dimensional architecture. We demonstrate that there is no significant difference in capillary density measurements between svOCT and histology images for all networks. Capillary diameter was significantly greater in svOCT images compared to histology for all networks. Capillary density measurements were also higher in svOCT compared to FA. The results of this study suggest that in vivo svOCT imaging allows accurate morphometric assessment of capillary networks in the human perifovea and may provide an improved ability to render microvascular detail compared to FA. Therefore, svOCT may have broad clinical applications in the study of human retinal physiology and disease. The difference in quantitative measurements between svOCT and histology may reflect dynamic variations in the retinal microcirculation and warrants further investigation. PMID:25917012

  16. To determine and compare the position of neutral zone in relation to crest of mandibular alveolar ridge with different duration of edentulousness: A clinico–radiographic study

    PubMed Central

    Jain, Ajay; Shetty, N. Sridhar; Ugrappa, Sridevi

    2015-01-01

    Purpose: The purpose of this study was to establish a relation between the crest of alveolar ridge and functionally obtained neutral zone and to determine the effect of duration of edentulousness on the location of neutral zone in relation to the crest of residual alveolar ridge. Materials and Methods: The study included three groups: Group I–15 subjects edentulous for 0 months to 2 years; Group 2–15 subjects edentulous for 2–5 years; and Group 3–15 subjects edentulous for more than 5 years. Neutral zone recording was performed for each subject and the buccolingual relationship of the crest of the mandibular alveolar ridge and position of the neutral zone was examined. The results were analyzed by the Kruskal–Wallis H test and the Chi-square test. Results: The results suggested that the location of the neutral zone varies from individual to individual depending on their musculature and that there is a significant relation to the duration of edentulousness. As edentulousness increases, there is more lingual positioning of the neutral zone at the molar region of both sides of the arch. At the premolar region, there is no change in position of the neutral zone; it remains constant as resorption of the alveolar ridge is directly under the buttress. In the anterior region, there is more labial positioning of the neutral zone as edentulousness increases. Conclusions: This technique proves itself to be an easy and inexpensive way to determine the relationship between the crest of alveolar ridge and neutral zone. Incorporating this technique into practice will be a great aid that can be exploited by the clinicians for functional and psychological comfort of the patients. PMID:25767354

  17. Clinico-pathological features of tuberculosis due to Mycobacterium tuberculosis Uganda genotype in patients with tuberculous lymphadenitis: a cross sectional study

    PubMed Central

    2014-01-01

    Background Tuberculous lymphadenitis is next to pulmonary tuberculosis as the most common cause of tuberculosis. Uganda genotype, one of the sub-lineages of Mycobacterium tuberculosis, is the most prevalent cause of pulmonary tuberculosis in Uganda. We here investigate the clinicopathological characteristics of patients with tuberculous lymphadenitis infected with M. tuberculosis Uganda genotype compared with those infected with M. tuberculosis non-Uganda genotype strains. Methods Between 2010 and 2012, we enrolled 121 patients (mean age 28.5 yrs, male 48%; female 52%) with tuberculous lymphadenitis, and categorized them by their M. tuberculosis genotypes. The clinical features and lymph node cytopathological parameters were compared between patients in the Uganda and non-Uganda categories using a crude and multivariable logistic regression model with adjustment for confounding factors. Results Of the 121participants, 56 (46%) were infected with strains of Uganda genotype. Patients infected with this genotype had significantly lower frequency of abdominal lymphadenopathy (odds ratio 0.4, p?=?0.046) after adjusting for sex, age and HIV. Abdominal lymphadenopathy was also significantly associated with abnormal chest X-ray (p?=?0.027). Conclusion Tuberculous lymphadenitis patients infected with M. tuberculosis Uganda genotype were significantly less prone to have abdominal lymphadenopathy indicating potential reduced ability to disseminate and supporting the concept that differences in M. tuberculosis genotype may have clinical implications. PMID:24690344

  18. Clinical evaluation of hydroxyapatite and ?-tricalcium phosphate composite graft in the treatment of intrabony periodontal defect: A clinico-radiographic study

    PubMed Central

    Bansal, Rajat; Patil, Sudhir; Chaubey, Krishna Kumar; Thakur, Rajesh Kumar; Goyel, Purnita

    2014-01-01

    Background and Objective: Hydroxyapatite (HA) and ?-tricalcium phosphate (?-TCP) grafts have shown to be effective in promoting the clinical signs of periodontal regeneration in intrabony defects. The aim of our study was to clinically and radiographically evaluate the efficacy of HA and ?-TCP composite bone graft material in the treatment of intrabony three-wall defect. Materials and Methods: Twenty patients participated in this study. Interproximal bony defects were surgically treated with a combination of HA–?TCP (biphasic calcium phosphate). Changes in clinical parameters such as gingival status, probing pocket depth, clinical attachment, and radiographic estimation of the amount of bone fill were evaluated after 6 months postoperatively. Statistical Analysis Used: Student's “t” test. Results: This treatment modality resulted in significant pocket depth reduction and clinical attachment gain which were observed to be 2.938 mm (47.04%) and 3.188 mm (29.09%), respectively. The defect fill as seen radiographically was 3.204 mm (63.195%). All the differences were highly significant and in favor of postoperative group. Conclusion: The results of this study suggest that HA–?TCP (biphasic calcium phosphate) provides an added regenerative effect in promoting the clinical resolution of intrabony three-wall defects in patients with periodontitis. PMID:25425823

  19. Hypersensitivity to pollen of four different species of Brassica: a clinico-immunologic evaluation in patients of respiratory allergy in India

    PubMed Central

    Shahi, Shipra; Katiyar, Raj Kishore; Gaur, Shailendra; Jain, Vikram

    2014-01-01

    Background Rapeseed-mustard is the second most important source of edible oil in India. Several species of Brassica are grown in different parts of country for its oilseeds. Objective The objective was to investigate allergenicity to antigenic extracts of pollen of 4 species of Brassica. Methods Brassica campestris, Brassica juncea, Brassica nigra, and Brassica napus were selected for the detailed investigation. Pollen samples from each of the four species were collected from the polliniferous materials. The antigenic and allergenic profiles of these extracts were evaluated by means of sodium dodecyl sulfate-polyacrylamide gel electrophoresis, Skin prick test, enzyme linked immuno sorbent assay and Western blot on atopic individuals. Results Out of the 159 atopic subjects tested, 21.38% were positive to at least one or other species of Brassica pollen, with highest skin positivity (13.20%) to B. campestris extract. Raised IgE with significant linear correlation with intensity of skin reactions was obtained. Protein fractions of 20, 25, 32, 37, 56, and 90 kDa were recognized by B. campestris and B. juncea whereas 56, 76, 87, and 90 kDa were recognized by B. nigra and B. napus as major IgE binding protein fractions. The patients also showed positivity to other inhalant pollen allergens tested. Conclusion IgE mediated hypersensitivity varied from 4.40% to 13.20% in Indian atopic subjects to pollen of one or the other species of Brassica. Protein fractions of 47, 56, 76, 87, and 90 kDa were identified as IgE binding by all the four species, however individual heterogeneity exists. Thus a local species may be more pertinent for immunotherapy. The major allergen needs to be further characterized. PMID:25379479

  20. On the role of localized surface plasmon resonance in UV-Vis light irradiated Au/TiO? photocatalysis systems: pros and cons.

    PubMed

    Lin, Zhongjin; Wang, Xiaohong; Liu, Jun; Tian, Zunyi; Dai, Loucheng; He, Beibei; Han, Chao; Wu, Yigui; Zeng, Zhigang; Hu, Zhiyu

    2015-03-01

    The role of localized surface plasmon resonance (LSPR) in UV-Vis light irradiated Au/TiO2 photocatalysis systems has been investigated, and it is demonstrated experimentally for the first time that both pros and cons of LSPR exist simultaneously for this photocatalytic reaction. We have proved that when operating under mixed UV and green light irradiation, the LSPR injected hot electrons (from the Au nanoparticles to TiO2 under green light irradiation) may surmount the Schottky barrier (SB) formed between the Au nanoparticles and TiO2, and flow back into the TiO2. As a result, these electrons may compensate for and even surpass those transferred from TiO2 to the Au nanoparticles, thus accelerating the recombination of UV excited electron-hole pairs in TiO2. This is the negative effect of LSPR. On the other hand, more hot electrons existing on the surface of the Au nanoparticles due to LSPR would favor the photocatalytic reaction, which accompanied by the negative effect dominates the overall photocatalytic performance. The presented results reveal the multi-faceted essence of LSPR in Au/TiO2 structures, and is instructive for the application of metal-semiconductor composites in photocatalysis. Moreover, it is confirmed that the extent to which the above pros and cons of LSPR dominate the overall photocatalytic reaction depends on the intensity ratio of visible to UV light. PMID:25665512

  1. FACTORES SOCIO-ESTRUCTURALES Y EL ESTIGMA HACIA EL VIH/SIDA: EXPERIENCIAS DE PUERTORRIQUEÑOS/AS CON VIH/SIDA AL ACCEDER SERVICIOS DE SALUD

    PubMed Central

    RIVERA-DIAZ, MARINILDA; VARAS-DIAZ, NELSON; REYES-ESTRADA, MARCOS; SURO, BEATRIZ; CORIANO, DORALIS

    2013-01-01

    RESUMEN El estigma relacionado al VIH/SIDA continúa afectando la prestación de servicios de salud y el bienestar físico y mental de las personas con VIH/SIDA (PVS). Recientemente la literatura científica ha señalado la importancia de comprender las manifestaciones de estigma más allá de las interacciones individuales. Por tal razón, investigaciones recientes en y fuera de Puerto Rico enfatizan la importancia de entender cómo factores socio-estructurales (FSE) influyen en los procesos de estigmatización social. Con el propósito de examinar los FSE que influyen en las manifestaciones de estigma relacionado al VIH/SIDA, realizamos y analizamos nueve grupos focales compuestos por hombres y mujeres en tratamiento para el VIH/SIDA que habían tenido experiencias estigmatizantes. Los participantes identificaron FSE relacionados a las manifestaciones de estigma, tales como el uso de viviendas especializadas, descentralización de los servicios de salud y el desarrollo de protocolos administrativos excluyentes en los servicios de salud. Los resultados demuestran la importancia de considerar los FSE en el desarrollo e implementación de intervenciones dirigidas a la población. PMID:24639599

  2. Aceptabilidad del diagnóstico rápido casero para HIV entre hombres gay y otros hombres que tienen sexo con hombres (G&HSH) de la Ciudad de Buenos Aires

    PubMed Central

    Balán, Iván C.; Carballo-Diéguez, Alex; Marone, Rubén O.; Pando, María A.; Barreda, Victoria; Ávila, María M.

    2011-01-01

    Resumen El uso del diagnóstico rápido para HIV en Argentina, así como otros países de Latinoamérica, ha sido limitado hasta el momento. Este trabajo reporta los resultados provenientes de un estudio cualitativo realizado entre hombres gays y otros hombres que tienen sexo con hombres (G&HSH) de la Ciudad de Buenos Aires, Argentina. El objetivo principal del mismo fue conocer las ventajas y desventajas que los hombres G&HSH perciben en relación al diagnóstico rápido casero para HIV. Se realizaron ocho grupos focales con 73 participantes en los cuales se discutió acerca de las ventajas y desventajas del uso de los diagnósticos rápidos. Las respuestas fueron codificadas utilizando un programa para análisis de datos cualitativos (NVivo) y analizadas temáticamente. Los participantes describieron numerosas ventajas sobre el uso del diagnóstico rápido casero, aunque algunos reportaron importantes preocupaciones dentro de las cuales se destaca la posibilidad de impulsos suicidas si alguien recibe un resultado positivo estando solo. En términos generales se observó una gran aceptabilidad para el uso del diagnóstico rápido si el mismo es realizado por personal de salud en lugares acondicionados para este fin. PMID:25284951

  3. Genes related to the very early stage of ConA-induced fulminant hepatitis: a gene-chip-based study in a mouse model

    PubMed Central

    2010-01-01

    Background Due to the high morbidity and mortality of fulminant hepatitis, early diagnosis followed by early effective treatment is the key for prognosis improvement. So far, little is known about the gene expression changes in the early stage of this serious illness. Identification of the genes related to the very early stage of fulminant hepatitis development may provide precise clues for early diagnosis. Results Balb/C mice were used for ConA injection to induce fulminant hepatitis that was confirmed by pathological and biochemical examination. After a gene chip-based screening, the data of gene expression in the liver, was further dissected by ANOVA analysis, gene expression profiles, gene network construction and real-time RT-PCR. At the very early stage of ConA-triggered fulminant hepatitis, totally 1,473 genes with different expression variations were identified. Among these, 26 genes were finally selected for further investigation. The data from gene network analysis demonstrate that two genes, MPDZ and Acsl1, localized in the core of the network. Conclusions At the early stages of fulminant hepatitis, expression of twenty-six genes involved in protein transport, transcription regulation and cell metabolism altered significantly. These genes form a network and have shown strong correlation with fulminant hepatitis development. Our study provides several potential targets for the early diagnosis of fulminant hepatitis. PMID:20398290

  4. The soil-water balance simulations of a grassland in response to CO2, rainfall, and biodiversity manipulations at BioCON

    NASA Astrophysics Data System (ADS)

    Flinker, R. H.; Cardenas, M.; Caldwell, T. G.; Rich, R.; Reich, P.

    2013-12-01

    The BioCON (Biodiversity, CO2 and N) experiment has been continuously running since 1997. Operated by the University of Minnesota and located within the Cedar Creek Ecosystem Science Reserve in Minnesota, USA, BioCON is a Free-Air CO2 Enrichment (FACE) experiment that investigates plant community response to three key environmental variables: nitrogen, atmospheric CO2 and biodiversity. More recently rainfall exclusion and temperature manipulation were added to the experiment which amounts to 371 plots. The site attempts to replicate predicted average temperature increases and a northern shift of plant species and any associated consequences. FACE experiments have been conducted for a number of years in different countries, but the focus has generally been on how plant communities, soil respiration and microbes respond. Minimal work has been focused on the hydrologic aspects of these experiments which are potentially valuable for investigating global warming effects on local and plot-scale ecohydrology. Thus, the objective of this work is to characterize and model unsaturated flow for different CO2 and rainfall treatments in order to see how they affect soil moisture dynamics and groundwater recharge on grasslands of central Minnesota. Our study focuses on simulating soil moisture dynamics in eighteen of the BioCON plots: six bare plots with regular rainfall regimes (zero plant species, three plots with elevated atmospheric CO2 levels), six regular rainfall regimes (nine plant species, three plots with elevated atmospheric CO2 levels) and six reduced rainfall regimes (nine plant species, three plots with elevated atmospheric CO2 levels). The Simultaneous Heat and Water (SHAW) model, which solves the Richards equation for unsaturated zone water flow coupled to a comprehensive energy balance model, was parameterized with a combination of field and lab estimates of soil properties. Field estimates of saturated hydraulic conductivity using tension infiltrometers ranged from 9.8 x 10-4 to 6.7 x 10-3 cm/s. Soil cores were collected and analyzed for soil hydraulic properties (texture, unsaturated hydraulic conductivity and moisture retention). From the grain size analyzes of soil samples collected every 10 cm until 1m depth, the soil is homogenous and on average 87% sand, 11% silt and 2% clay. We will be presenting results from the simulations and statistical comparisons to observations of soil moisture at four depths in each plot.

  5. Do the Symptom-Based, Rome Criteria of Irritable Bowel Syndrome Lead to Better Diagnosis and Treatment Outcomes? The Con Argument

    PubMed Central

    Camilleri, Michael

    2009-01-01

    Some claim that symptom-based Rome criteria are diagnostic and enhance clinical practice and choice of therapy for patients presenting with gastrointestinal symptoms. This overview focuses on lower gastrointestinal symptoms: constipation, diarrhea, pain and bloating. The main con arguments for using such criteria for diagnosis are: insufficient specificity, overlap of symptom-based categories or disorders, insufficient and therefore non-specific characterization of pain in the criteria, inability to differentiate the “mimics” of IBS-C and IBS-D, and inability to optimize treatment for IBS-M or bloating in the absence of objective measurements. While doctors may not land in trouble using “symptom diagnosis” of IBS, this should not deter them from optimizing diagnosis and treatment of diseases associated with gastrointestinal dysfunction. PMID:20182528

  6. The role of intracellular high-mobility group box 1 in the early activation of Kupffer cells and the development of Con A-induced acute liver failure.

    PubMed

    Yang, Qiao; Liu, Yanning; Shi, Yu; Zheng, Min; He, Jiliang; Chen, Zhi

    2013-10-01

    Acute liver failure (ALF) is a highly complex syndrome characterized by devastating activation of early activation of Kupffer cells (KCs) has been implicated in the pathogenesis of ALF. However, the factors regulating KC early activation are virtually unexplored. The aim of present study was to determine the role of the intracellular high-mobility group box 1 (HMGB1) in modulating the early activation of KCs during ALF. The intravenous injection of Concanavalin A (Con A) was used to establish a mouse model of ALF. The dynamic pro-inflammatory properties and MHC II expression of KCs were measured by qRT-PCR and flow cytometry. HMGB1 expression in KCs was measured by qRT-PCR and Western blotting. The immunofluorescence was implemented to determine the relocation of HMGB1 in KCs, and the siRNA against HMGB1 was utilized to assess the impact of HMGB1 on KC pro-inflammatory properties. The peak of pro-inflammatory cytokines production and MHC II expression in KCs appeared at the early stage of ALF. The up-regulation of HMGB1 expression and the translocation of HMGB1 in KCs were in parallel with the early activation of KCs. The blockade of intracellular HMGB1 expression caused by siRNA significantly inhibited the production of KC-derived pro-inflammatory cytokines, and led to a down-regulation of MAP kinase activation in KCs. The self-derived HMGB1 is an "early alarmin" of KC activation during Con A-induced ALF. HMGB1 might be a potential target for cell-specific strategy in ALF. PMID:23706499

  7. EXPLORATORY SENSITIVITY ANALYSIS OF CROPSYST, WARM AND WOFOST: A CASESTUDY WITH RICE BIOMASS SIMULATIONS ANALISI ESPLORATIVA DELLA SENSIBILITÀ DI CROPSYST, WARM AND WOFOST: UN CASO DI STUDIO CON SIMULAZIONI DI BIOMASSA DEL RISO

    Microsoft Academic Search

    Roberto Confalonieri; Marco Acutis; Gianni Bellocchi; Iacopo Cerrani; Stefano Tarantola; Marcello Donatelli; Giampiero Genovese

    Knowledge about model uncertainty is essential for crop modelling and provides information crucial for a real understand- ing of models behavior and for parameterization purposes. This work addresses an exploratory sensitivity analysis on the parameters involved with biomass accumulation of three crop models decidedly differing in the way they interpret the con- cept of growth. The models used in the

  8. UNIVERSIT DEGLI STUDI DI SALERNO E 56CUBE: ACCORDO PER SOSTENERE LE STARTUP CON BUSINESS Il Dipartimento di Studi e Ricerche Aziendali -Management & Information Technology e l'incubatore per il Sud Italia,

    E-print Network

    Costagliola, Gennaro

    UNIVERSITÀ DEGLI STUDI DI SALERNO E 56CUBE: ACCORDO PER SOSTENERE LE STARTUP CON BUSINESS incubator di startup innovative nel Sud Italia ­ lanciato dall'incubatore certificato Digital Magics supportare startup digitali, strutturando un programma di Business Management Advisory. Questa partnership

  9. 08853010/$25.00 2009 IEEE 2145IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 56, no. 10, ocTobEr 2009

    E-print Network

    Khuri-Yakub, Butrus T. "Pierre"

    EqUEncy conTrol, vol. 56, no. 10, ocTobEr 2009 Abstract--State-of-the-art 3-D medical ultrasound imaging requires transmitting and receiving ultrasound using a 2-D array of ultrasound transducers with hundreds and transducer array can lead to a portable, high-performance, and inexpensive 3-D ultrasound imaging system

  10. Alla cortese attenzione dello Studente dell'Universit di Economia e Commercio di Genova Con la presente vorremmo sottoporre alla tua attenzione un progetto sulla eco-sostenibilit per il quale la nostra azienda

    E-print Network

    Robbiano, Lorenzo

    Genova Con la presente vorremmo sottoporre alla tua attenzione un progetto sulla eco-sostenibilità per il presente, una breve descrizione della nostra azienda. Techreturns International B.V. e' un'azienda eco significative nel campo dell'eco-sostenibilità presenti sul territorio italiano, appurare se sono impegnate

  11. 08853010/$25.00 2008 IEEE 1IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 55, no. 9, sEpTEmbEr 2008

    E-print Network

    Paris 7 - Denis Diderot, Université

    on the tissue velocity field estimation during con- traction, cine phase contrast mr [7] or ultrasound doppler system. In this paper we report the use of ultrafast ultrasound imag- ing to explore with a submillimeter is a very brief phenomenon (ultrasound scanner prototype able to take up

  12. A.U.L.A.S.: TABLA CORRESPONDENCIA NUEVOS CURSOS *En el caso de haber superado este nivel en cursos anteriores a 2008-2009, consulta con uno de

    E-print Network

    Escolano, Francisco

    A.U.L.A.S.: TABLA CORRESPONDENCIA NUEVOS CURSOS *En el caso de haber superado este nivel en cursos anteriores a 2008-2009, consulta con uno de INGLÉS CURSO realizado hasta 2007-2008 CURSO correspondiente Preparación CAE (C1) ALEMÁN CURSO realizado hasta 2007-2008 CURSO correspondiente a partir de 2008-2009 LENGUA

  13. 08853010/$25.00 2009 IEEE 2679IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 56, no. 12, dEcEmbEr 2009

    E-print Network

    Cao, Wenwu

    EqUEncy conTrol, vol. 56, no. 12, dEcEmbEr 2009 Abstract--Near-field acoustic levitation (NFAL) has been used with experimentally measured levitation force. I. Introduction acoustic levitation is one of the most suitable meth, insulator, or conductor, magnetic or nonmagnetic, can be manipulated by acoustic levitation

  14. Diffusional homogenization of light REE in garnet from the Day Nui Con Voi Massif in N-Vietnam: Implications for SmNd geochronology and timing of metamorphism in

    E-print Network

    Demouchy, Sylvie

    Diffusional homogenization of light REE in garnet from the Day Nui Con Voi Massif in N Department of Earth Sciences, Royal Holloway University of London, Egham, Surrey, TW20 0EX, UK c Department of Earth and Environmental Sciences, The Open University, Walton Hall Milton Keynes MK7 6AA, UK d Institute

  15. Surgical treatment of prolactinomas: cons.

    PubMed

    Bloomgarden, Eve; Molitch, Mark E

    2014-12-01

    Prolactinomas account for approximately 40 % of all pituitary adenomas. Over 95 % of prolactinomas are microadenomas (< 10 mm diameter). Treatment is indicated to correct hypogonadism, restore other hormonal deficits, and alleviate local mass effects. Dopamine agonists (DA) are highly effective in achieving these goals and are well-tolerated. The vast majority of prolactinomas will respond to conventional doses of cabergoline (?2 mg/week) that do not carry an increased risk of cardiac valvular abnormalities. DA therapy may be successful withdrawn in a subset of patients and thus is not necessarily a lifelong commitment. Although transsphenoidal surgery (TSS) is an option for prolactinoma treatment, it is less effective than medical management, carries considerably more risk, and is more expensive. The benefit/risk ratio for DA therapy compared to TSS actually becomes increasingly more favorable as tumor size increases. Therefore DA should remain the clear treatment of choice for essentially all patients with prolactinomas, reserving TSS as a second-line option for the very small number of patients that do not tolerate or are completely resistant to DA therapy. PMID:25112227

  16. Maintaining Consistent, Minimal Con gurations

    E-print Network

    Perry, Dewayne E.

    as customer needs change. From the hardware point of view, the various inter- changeable components must be standardized and plug compatible. From the software point of view, there are two interdependent things needed the products. This means that, among other things, that system storage space is likely to be limited to just

  17. Liquen plano con afectación esofágica

    Microsoft Academic Search

    F. Valdés; A. Caparrini; J. M. Calzada

    2007-01-01

    Lichen planus is an inflammatory disease of unknown etiology which may affect the esophagus. Patients with esophageal lichen planus are usually elderly women. The most frequent symptoms are dysphagia and odynophagia. There is usually concomitant oral involvement in cases of esophageal lichen planus. Endoscopic findings include erosions, exudates and stenosis. Systemic steroids are the most effective therapy for these patients.

  18. ccepting con-structive criticism

    E-print Network

    Alpay, S. Pamir

    passionate about something you're doing? Your great ideas lie there. Important notice: Information in Front meditation." Summer Jobs for Teenagers You andYour GreatIdeas M ay is National Physi- cal Fitness Month in the National Runners' Health Study II and 15,945 walkers in the National Walkers' Health Study, assessing

  19. Biochar Usage: Pros and Cons

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Soil fertility benefits of charcoal application have been reported as early as 1847 indicating that plant nutrients are sorbed within charcoal pores. The use of biomass-derived black carbon or biochar, the solid byproduct from the pyrolysis processing of any organic feedstock, has garnered recent a...

  20. Coagulase-negative staphylococci (CoNS) isolated from ready-to-eat food of animal origin--phenotypic and genotypic antibiotic resistance.

    PubMed

    Chaj?cka-Wierzchowska, Wioleta; Zadernowska, Anna; Nalepa, Beata; Sierpi?ska, Magda; ?aniewska-Trokenheim, ?ucja

    2015-04-01

    The aim of this work was to study the pheno- and genotypical antimicrobial resistance profile of coagulase negative staphylococci (CoNS) isolated from 146 ready-to-eat food of animal origin (cheeses, cured meats, sausages, smoked fishes). 58 strains were isolated, they were classified as Staphylococcus xylosus (n = 29), Staphylococcus epidermidis (n = 16); Staphylococcus lentus (n = 7); Staphylococcus saprophyticus (n = 4); Staphylococcus hyicus (n = 1) and Staphylococcus simulans (n = 1) by phenotypic and genotypic methods. Isolates were tested for resistance to erythromycin, clindamycin, gentamicin, cefoxitin, norfloxacin, ciprofloxacin, tetracycline, tigecycline, rifampicin, nitrofurantoin, linezolid, trimetoprim, sulphamethoxazole/trimethoprim, chloramphenicol, quinupristin/dalfopristin by the disk diffusion method. PCR was used for the detection of antibiotic resistance genes encoding: methicillin resistance--mecA; macrolide resistance--erm(A), erm(B), erm(C), mrs(A/B); efflux proteins tet(K) and tet(L) and ribosomal protection proteins tet(M). For all the tet(M)-positive isolates the presence of conjugative transposons of the Tn916-Tn1545 family was determined. Most of the isolates were resistant to cefoxitin (41.3%) followed by clindamycin (36.2%), tigecycline (24.1%), rifampicin (17.2%) and erythromycin (13.8%). 32.2% staphylococcal isolates were multidrug resistant (MDR). All methicillin resistant staphylococci harboured mecA gene. Isolates, phenotypic resistant to tetracycline, harboured at least one tetracycline resistance determinant on which tet(M) was most frequent. All of the isolates positive for tet(M) genes were positive for the Tn916-Tn1545 -like integrase family gene. In the erythromycin-resistant isolates, the macrolide resistance genes erm(C) or msr(A/B) were present. Although coagulase-negative staphylococci are not classical food poisoning bacteria, its presence in food could be of public health significance due to the possible spread of antibiotic resistance. PMID:25475289

  1. De conformidad con la Ley de Derechos Humanos de 1977 del Distrito de Columbia, segn enmendada, Cdigo Oficial del Distrito de Columbia, Seccin 2-1401.01 et seq., (Ley), el Distrito de Columbia no discrimina, de forma visible ni percibida, por

    E-print Network

    Weaver, Harold A. "Hal"

    De conformidad con la Ley de Derechos Humanos de 1977 del Distrito de Columbia, según enmendada la ausencia, el empleado no perderá ninguno de sus beneficios de empleo, ni tampoco los derechos por las estipuladas por la Ley. LAS QUEJAS CON RESPECTO A ALGUNA DENEGACIÓN DE LOS DERECHOS EN VIRTUD DE

  2. arXiv:1009.4437v1[cond-mat.supr-con]22Sep2010 Pressure effects in PrT2B2C (T = Co, Ni, Pt): Applied and chemical pressure

    E-print Network

    Paris-Sud XI, Université de

    arXiv:1009.4437v1[cond-mat.supr-con]22Sep2010 Pressure effects in PrT2B2C (T = Co, Ni, Pt): Applied: November 1, 2013) High-pressure electrical resistivity ab measurements on intermetallic Pr(Co, Ni, Pt)2B2C Pr(Co, Ni)2B2C compounds exhibit magnetic correlations at about 10 and 4 K, respectively. At low

  3. SISTeMAS De INFoRMACIÓN: INTeRNeT, ACCeSo Y USo PoR TRABAJADoReS De SALUD Y PeRSoNAS VIVIeNDo CoN VIH\\/SIDA

    Microsoft Academic Search

    Patricia J. García; Patricia Caballero Ñ; Víctor Suárez M; Luis Fuentes-Tafur

    2007-01-01

    ReSUMeN El Instituto Nacional de Salud desarrolló NETLAB, un sistema de información basado en la Web que aumenta la disponibilidad de los resultados de laboratorio a los trabajadores de salud y a los pacientes viviendo con VIH\\/SIDA (PVVS). Para asegurar su efectividad se requiere conocer aspectos como recursos y acceso a Internet. Objetivos: Describir las características del acceso a Internet

  4. 9/7/10 3:32 PMShineCon Page 1 of 1file:///Users/Chungsang/g6/Meeting/SHINE10/AbstractPreview.php.html

    E-print Network

    Ng, Chung-Sang

    9/7/10 3:32 PMShineCon Page 1 of 1file:///Users/Chungsang/g6/Meeting/SHINE10/AbstractPreview.php based on the island coalescence instability, using much higher resolutions (up to 8192^2) and larger S (up to 2 x 10^5). Our simulations are based on a fairly standard pseudo spectral code, which has been

  5. Reversible CO binding enables tunable CO/H? and CO/N? separations in metal-organic frameworks with exposed divalent metal cations.

    PubMed

    Bloch, Eric D; Hudson, Matthew R; Mason, Jarad A; Chavan, Sachin; Crocellà, Valentina; Howe, Joshua D; Lee, Kyuho; Dzubak, Allison L; Queen, Wendy L; Zadrozny, Joseph M; Geier, Stephen J; Lin, Li-Chiang; Gagliardi, Laura; Smit, Berend; Neaton, Jeffrey B; Bordiga, Silvia; Brown, Craig M; Long, Jeffrey R

    2014-07-30

    Six metal-organic frameworks of the M2(dobdc) (M = Mg, Mn, Fe, Co, Ni, Zn; dobdc(4-) = 2,5-dioxido-1,4-benzenedicarboxylate) structure type are demonstrated to bind carbon monoxide reversibly and at high capacity. Infrared spectra indicate that, upon coordination of CO to the divalent metal cations lining the pores within these frameworks, the C-O stretching frequency is blue-shifted, consistent with nonclassical metal-CO interactions. Structure determinations reveal M-CO distances ranging from 2.09(2) Å for M = Ni to 2.49(1) Å for M = Zn and M-C-O angles ranging from 161.2(7)° for M = Mg to 176.9(6)° for M = Fe. Electronic structure calculations employing density functional theory (DFT) resulted in good agreement with the trends apparent in the infrared spectra and crystal structures. These results represent the first crystallographically characterized magnesium and zinc carbonyl compounds and the first high-spin manganese(II), iron(II), cobalt(II), and nickel(II) carbonyl species. Adsorption isotherms indicate reversible adsorption, with capacities for the Fe, Co, and Ni frameworks approaching one CO per metal cation site at 1 bar, corresponding to loadings as high as 6.0 mmol/g and 157 cm(3)/cm(3). The six frameworks display (negative) isosteric heats of CO adsorption ranging from 52.7 to 27.2 kJ/mol along the series Ni > Co > Fe > Mg > Mn > Zn, following the Irving-Williams stability order. The reversible CO binding suggests that these frameworks may be of utility for the separation of CO from various industrial gas mixtures, including CO/H2 and CO/N2. Selectivities determined from gas adsorption isotherm data using ideal adsorbed solution theory (IAST) over a range of gas compositions at 1 bar and 298 K indicate that all six M2(dobdc) frameworks could potentially be used as solid adsorbents to replace current cryogenic distillation technologies, with the choice of M dictating adsorbent regeneration energy and the level of purity of the resulting gases. PMID:24999916

  6. Do not disturb the animals! or, how Con Edison saved $300,000 using a trenchless technology to renew 3,000 feet of leaking gas main at the Bronx Zoo

    SciTech Connect

    Bufe, M.

    1995-07-01

    Every leaking gas main presents a challenge. But when that leaking main follows a series of sweeping bends on its route through North America`s largest urban wildlife park, it presents a special challenge. That was the situation Consolidated Edison Company of New York Inc. recently faced when numerous leaks were discovered along 3,000 feet of a 95-year-old, 12-inch cast-iron main that winds through New York City`s Bronx Zoo. Con Edison knew it needed a long-term solution to this increasingly common problem. Thanks to the cooperative efforts of the utility`s operations and research departments and the Gas Research Institute (GRI), Con Edison also knew about a trenchless technology that could renew the pipe with minimal impact to the environment--while saving the utility a substantial sum of money in the process. In the Paltem system, a woven polyester hose is injected with an epoxy resin and then inverted (turned inside out) into a pipe at an access pit. The liner then bonds to the inside wall of the pipe, forming a smooth, flexible and pressure-resistant lining. The process is environmentally safe, requires very little excavation and can be installed in days, rather than the weeks or months it can take to dig up and replace existing pipe.

  7. Coordinator(a) de Servicios Clinicos. Parte I (Unidad I-IV). Parte II (Unidad V-VI). Guia. Documento de Trabajo (Clinical Services Coordinator. Part I. Units I-IV. Part II. Units V-VI. Guide. Working Document).

    ERIC Educational Resources Information Center

    Puerto Rico State Dept. of Education, Hato Rey. Area for Vocational and Technical Education.

    This guide is intended for instructing secondary students in the occupation of clinical services coordinator in a hospital. The first part contains four units on the following subjects: the occupation of clinical services coordinator; interpersonal relationships; ethical/legal aspects; and communications (telephone, intercom, and others). For each…

  8. Early-stage diffuse large B cell lymphoma of the head and neck: clinico-biological characterization and 18 year follow-up of 488 patients (IELSG 23 study).

    PubMed

    Mian, M; Capello, D; Ventre, M B; Grazio, D; Svaldi, M; Rossi, A; Tsang, R; Gospodarowicz, M K; Oldani, E; Federico, M; Luminari, S; Marcheselli, L; Pogliani, E M; Rossini, F; Cabrera, M E; Martelli, M; Gutierrez-Garcia, G; Busetto, M; Visco, C; Fiegl, M; Rossi, D; Gaidano, G; Cavalli, F; Zucca, E; Rambaldi, A; Cortelazzo, S

    2013-08-20

    It is known that extranodal head and neck diffuse large B cell lymphomas (eHN-DLBCL) can affect various anatomical structures what is not well-known, however, is whether they differ in terms of clinical presentation and outcome. Clinical data of the multi-institutional series, the largest of its kind as yet, has been analysed with the aim of answering these open questions and providing long-term follow-up information. Data from 488 patients affected by stage I/II eHN-DLBCL was collected: 300 of the Waldeyer's Ring (WR), 38 of the parotid and salivary glands (PSG), 48 of the thyroid gland (TG), 53 of the nasal cavity and paranasal sinuses (NPS), 24 of the palate and oral cavity (POC) and 25 with more than one involved site. Different eHN-DLBCL arising have distinct characteristics at presentation. The intermediate high risk-modified IPI was 67 % in TG, 44 % in WR, 38 % in PSG and POC and 20 % in MS. The worst 5-year survival rate had TG-DLBCL (61 %) due to the 61 % of patients with a mIPI >1. The addition of radiotherapy (cRT) to remitters did not translate into a survival advantage (5-year disease-free survival of 67 % in the cRT group vs. 70 % in the other). Three of four central nervous system recurrences occurred in NPS-DLBCL. Survival of HN-DLBCL was inferior to nodal DLBCL. This study showed that eHN-DLBCL remitters have an inferior survival when compared to nodal DLBCL, and that the addition of cRT does not provide a survival advantage. Since the standard of care nowadays is chemo-immunotherapy, survival of these patients might have been improved. PMID:23959436

  9. UTILIZACIÓN DE RESIDUOS DE PLÁTANO PARA LA PRODUCCIÓN DE METABOLITOS SECUNDARIOS POR FERMENTACIÓN EN ESTADO SÓLIDO CON EL HONGO Lentinus crinitus UTILIZATION OF PLANTAIN WASTE FOR THE PRODUCTION OF SECONDARY ME TABOLITES BY SOLID SUBSTRATE FERMENTATION USING THE FUNGI Lentinus crinitus

    Microsoft Academic Search

    GRANDA R. Diana; JIMÉNEZ T. Gloria; REVISTA DE LA FACULTAD DE QUÍMICA

    2005-01-01

    This paper presents the production of secondary metabolites with pharmaceutical and alimentary interest from plantain waste used as substrate in a solid state fermentation process with the white root fungi Lentinus crinitus . The production of metabolites is studied during the growth of the microorganism for a period of 21 days, in a system con-

  10. Empiece con el desayuno Coma buenos bocadillos

    E-print Network

    , color, sexo, religión, origen nacional, edad, discapacidad, información genética, o condición de las personas, sin distinción de raza, color, sexo, religión, origen nacional, edad, discapacidad, color, sexo, religión, origen nacional, edad, discapacidad, información genética, o condición de

  11. Mercadeo con causasocial: ¿Responsabilidad social o estrategiacomercial?

    Microsoft Academic Search

    Juan Vianey Gómez Jiménez

    2004-01-01

    La necesidad de ser competitivos ha llevado a la gerencia de las empresas a buscar diferentes formas o alternativas de alcanzar la diferenciación de sus productos y servicios. Atendiendo a las actuales tendencias, las decisiones de diferenciación han estado basadas en lo que los clientes y ciudadanos consideran importante. Estos, frente a los continuos cambios económicos y sociales al igual

  12. The Big Con: China's Historical Sabotage

    ERIC Educational Resources Information Center

    Terrence Cheng

    2009-01-01

    On June 4, 1989, the Chinese military, under orders from the highest levels of government, violently crushed peaceful civilian demonstrations in Beijing, most symbolically in and around Tiananmen Square. In the end, the Chinese government claimed that the death toll was approximately 200, but the Chinese Red Cross reported 2,000 to 3,000 deaths.…

  13. ORNL/CON-224 Energy Division

    E-print Network

    Oak Ridge National Laboratory

    ..................................... 148 7.1 Stirling Engine-Driven Systems ................................. ..... 148 7.2 Internal Combustion Engine-Driven Systems ......................... 170 7.3 Rankine, Brayton, and Other Engine

  14. Planetas extrasolares con pequeño semieje orbital

    Microsoft Academic Search

    D. Giuliodori; S. Fernández

    2002-01-01

    The discovery of extra-solar planets, first surrounding a pulsar (PSR1257+12, Malhotra et al 1992) and then main-sequence stars similar to our sun, (http:\\/\\/exoplanets.org) has opened a new field of study inside the dynamic of planetary systems. Although the information we have of these objects is determined by the own limitations of the detection methods that are used, important differences between

  15. Con la apertura UniversidaddeAlicante

    E-print Network

    Escolano, Francisco

    ciclo de Relaciones Laborales". 2º Por diversos avatares técnicos, administrativos y políticos, se ha ocasiones, han frenado el proceso de reforma de sus actuales planes de estudios o su reorganización académi

  16. Cálculos ab initio con correlación electrónica

    Microsoft Academic Search

    M. Merchán Bonete

    2003-01-01

    Estamos entrando en una era donde la ortogonalidad entre las investigaciones de carácter experimental y de naturaleza teórica se irá difuminando progresivamente y la problemática a resolver quedará en escena como el único actor principal de la obra. Como premisa para una cooperación teórico-experimental de igual a igual, la metodología químico-cuántica utilizada debe ser capaz de ofrecer resultados de carácter

  17. Bovine Spongiform Encephalopathy: Atypical Pros and Cons

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Transmissible spongiform encephalopathies (TSEs) are fatal neurologic diseases that affect several mammalian species including human beings. Four animal TSE agents have been reported: scrapie of sheep and goats; chronic wasting disease (CWD) of deer, elk, and moose; transmissible mink encephalopath...

  18. MSP | LABORSALUS TRABAJO CON PANTALLAS DE VISUALIZACIN

    E-print Network

    Cardeñosa, Jesús

    . Fatiga mental. Síntomas: Estrés y cansancio o Trastornos neurovegetativos (somatizaciones, palpitaciones, etc.) o Perturbaciones tales como ansiedad, irritabilidad. o Trastornos del sueño (insomnio, irritación, pesadez de párpados, etc. o Trastornos visuales (borrosidad) o Síntomas extraoculares (cefaleas

  19. Synthetic chemicals have been components of con-

    E-print Network

    Cai, Long

    experi- mental animals are used1 and that products worth 5.6 trillion are regulated by such testing with the current approach to toxicology testing? An ideal study to under- stand whether an agent is harmful. The crucial question therefore is how useful are the cur- rent models, which are mostly animal models, and how

  20. Asistencia de pacientes con fibrosis quística

    Microsoft Academic Search

    Birgitta Strandvik

    2006-01-01

    ExtractoLa fibrosis quística (FQ), la enfermedad pediátrica hereditaria autosómica más corriente, ha dejado de estar limitada a la infancia desde que la terapia moderna ha proporcionado a los pacientes una mayor longevidad y una mejor calidad de vida. Cuando se identificó el gen, hace más de 16 años, y se descubrió la mutación más corriente, ?F508, se suscitó la esperanza