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Sample records for range system viability

  1. Range and range rate system

    NASA Technical Reports Server (NTRS)

    Graham, Olin L. (Inventor); Russell, Jim K. (Inventor); Epperly, Walter L. (Inventor)

    1988-01-01

    A video controlled solid state range finding system which requires no radar, high power laser, or sophisticated laser target is disclosed. The effective range of the system is from 1 to about 200 ft. The system includes an opto-electric camera such as a lens CCD array device. A helium neon laser produces a source beam of coherent light which is applied to a beam splitter. The beam splitter applies a reference beam to the camera and produces an outgoing beam applied to a first angularly variable reflector which directs the outgoing beam to the distant object. An incoming beam is reflected from the object to a second angularly variable reflector which reflects the incoming beam to the opto-electric camera via the beam splitter. The first reflector and the second reflector are configured so that the distance travelled by the outgoing beam from the beam splitter and the first reflector is the same as the distance travelled by the incoming beam from the second reflector to the beam splitter. The reference beam produces a reference signal in the geometric center of the camera. The incoming beam produces an object signal at the camera.

  2. Improved ranging systems

    NASA Technical Reports Server (NTRS)

    Young, Larry E.

    1989-01-01

    Spacecraft range measurements have provided the most accurate tests, to date, of some relativistic gravitational parameters, even though the measurements were made with ranging systems having error budgets of about 10 meters. Technology is now available to allow an improvement of two orders of magnitude in the accuracy of spacecraft ranging. The largest gains in accuracy result from the replacement of unstable analog components with high speed digital circuits having precisely known delays and phase shifts.

  3. Economic viability of beef cattle grazing systems under prolonged drought

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Prolonged drought in the Southern Great Plains of the USA in recent years has raised concerns about vulnerability of beef cattle grazing systems under adverse climate change. To help address the economic viability of beef grazing operations in the Southern Great Plains, this paper provides an econom...

  4. Non-disruptive measurement system of cell viability in bioreactors

    NASA Astrophysics Data System (ADS)

    Rudek, F.; Nelsen, B. L.; Baselt, T.; Berger, T.; Wiele, M.; Prade, I.; Hartmann, P.

    2016-04-01

    Nutrient and oxygen transport, as well as the removal of metabolic waste are essential processes to support and maintain viable tissue. Current bioreactor technology used to grow tissue cultures in vitro has a fundamental limit to the thickness of tissues. Based on the low diffusion limit of oxygen a maximum tissue thickness of 200 μm is possible. The efficiency of those systems is currently under investigation. During the cultivation process of the artificial tissue in bioreactors, which lasts 28 days or longer, there are no possibilities to investigate the viability of cells. This work is designed to determine the influence of a non-disruptive cell viability measuring system on cellular activity. The measuring system uses a natural cellular marker produced during normal metabolic activity. Nicotinamide adenine dinucleotide (NADH) is a coenzyme naturally consumed and produced during cellular metabolic processes and has thoroughly been studied to determine the metabolic state of a cell. Measuring the fluorescence of NADH within the cell represents a non-disruptive marker for cell viability. Since the measurement process is optical in nature, NADH fluorescence also provides a pathway for sampling at different measurement depths within a given tissue sample. The measurement system we are using utilizes a special UV light source, to excite the NADH fluorescence state. However, the high energy potentially alters or harms the cells. To investigate the influence of the excitation signal, the cells were irradiated with a laser operating at a wavelength of 355 nm and examined for cytotoxic effects. The aim of this study was to develop a non-cytotoxic system that is applicable for large-scale operations during drug-tissue interaction testing.

  5. Demonstrating the Viability and Affordability of Nuclear Surface Power Systems

    NASA Technical Reports Server (NTRS)

    Vandyke, Melissa K.

    2006-01-01

    A set of tasks have been identified to help demonstrate the viability, performance, and affordability of surface fission systems. Completion of these tasks will move surface fission systems closer to reality by demonstrating affordability and performance potential. Tasks include fabrication and test of a 19-pin section of a Surface Power Unit Demonstrator (SPUD); design, fabrication, and utilization of thermal simulators optimized for surface fission' applications; design, fabrication, and utilization of GPHS module thermal simulators; design, fabrication, and test of a fission surface power system shield; and work related to potential fission surface power fuel/clad systems. Work on the SPUD will feed directly into joint NASA MSFC/NASA GRC fabrication and test of a surface power plant Engineering Development Unit (EDU). The goal of the EDU will be to perform highly realistic thermal, structural, and electrical testing on an integrated fission surface power system. Fission thermal simulator work will help enable high fidelity non-nuclear testing of pumped NaK surface fission power systems. Radioisotope thermal simulator work will help enable design and development of higher power radioisotope systems (power ultimately limited by Pu-238 availability). Shield work is designed to assess the potential of using a water neutron shield on the surface of the moon. Fuels work is geared toward assessing the current potential of using fuels that have already flown in space.

  6. Influence of a range of extreme environmental factors on tripartite lichen Peltigera aphthosa thallus viability

    NASA Astrophysics Data System (ADS)

    Irina, Insarova; Dyakov, Max; Ptushenko, Vasiliy; Shtaer, Oksana

    Lichens are symbiotic organisms consisting of at least two genetic different partners: a heterotrophic fungus (mycobiont) and a phototrophic alga or cyanobacterium (photobiont). Lichens are ubiquitous at global scale. These symbiotic organisms represent the dominant type of “vegetation” at 8 - 10% of land (Larson, 1987). Abiotic stress’ resistance is notable for lichens among all eukaryotes. Lichens are often called “extremophiles” for their ability to acclimate the most severe environmental conditions. These features allow regarding lichens as a group of organisms which is potentially able to keep viability under open space conditions and to survive within Mars-like atmosphere types. The research presented was carried out in the network of spacecraft Bion-1 experiments involving the investigation of physiological and ultrastructural changes in biological objects survivable under open space conditions. Similar researches were already conducted on bipartite lichen species. The most attention was paid to the influence of UV and other space radiation types on lichen viability in those works. Thus we have taken tripartite lichen Peltigera aphthosa as a main research object and temperature fluctuations from extremely high to extremely low values in accordance to solar and umbral orbit sides - for the main extreme environmental factors. These factors were the less studied in previous works. During the research the influence of incubation under anaerobic conditions, multi-time effects of high and low temperatures and their interchange on respiratory metabolism, photosynthetic apparatus condition and the ultrastructure of P. aphthosa thalli was assessed. The data obtained demonstrate that activity either mycobiont or photobiont in tripartite lichen Peltigera aphthosa keep near unchanged under influence of all stress factors explored on dry thalli.

  7. Identification, Description, and Perceived Viability of K-12 Consolidated Catholic School Systems

    ERIC Educational Resources Information Center

    Britt, Kenith C.

    2011-01-01

    Limited research has been conducted on Catholic school viability (James, Tichy, Collins, & Schwob, 2008; Lundy, 1999) and Catholic school systems (Goldschmidt, O'Keefe, & Walsh, 2004). But no research studies have investigated the viability of the consolidated Catholic school system (DeFiore, Convey, & Schuttloffel, 2009). This study investigates…

  8. Long range inductive power transfer system

    NASA Astrophysics Data System (ADS)

    Lawson, James; Pinuela, Manuel; Yates, David C.; Lucyszyn, Stepan; Mitcheson, Paul D.

    2013-12-01

    We report upon a recently developed long range inductive power transfer system (IPT) designed to power remote sensors with mW level power consumption at distances up to 7 m. In this paper an inductive link is established between a large planar (1 × 1 m) transmit coil (Tx) and a small planer (170 × 170 mm) receiver coil (Rx), demonstrating the viability of highly asymmetrical coil configurations that real-world applications such as sensor networks impose. High Q factor Tx and Rx coils required for viable power transfer efficiencies over such distances are measured using a resonant method. The applicability of the Class-E amplifier in very low magnetic coupling scenarios and at the high frequencies of operation required for high Q operation is demonstrated by its usage as the Tx coil driver.

  9. Viability of a Reusable In-Space Transportation System

    NASA Technical Reports Server (NTRS)

    Jefferies, Sharon A.; McCleskey, Carey M.; Nufer, Brian M.; Lepsch, Roger A.; Merrill, Raymond G.; North, David D.; Martin, John G.; Komar, David R.

    2015-01-01

    The National Aeronautics and Space Administration (NASA) is currently developing options for an Evolvable Mars Campaign (EMC) that expands human presence from Low Earth Orbit (LEO) into the solar system and to the surface of Mars. The Hybrid in-space transportation architecture is one option being investigated within the EMC. The architecture enables return of the entire in-space propulsion stage and habitat to cis-lunar space after a round trip to Mars. This concept of operations opens the door for a fully reusable Mars transportation system from cis-lunar space to a Mars parking orbit and back. This paper explores the reuse of in-space transportation systems, with a focus on the propulsion systems. It begins by examining why reusability should be pursued and defines reusability in space-flight context. A range of functions and enablers associated with preparing a system for reuse are identified and a vision for reusability is proposed that can be advanced and implemented as new capabilities are developed. Following this, past reusable spacecraft and servicing capabilities, as well as those currently in development are discussed. Using the Hybrid transportation architecture as an example, an assessment of the degree of reusability that can be incorporated into the architecture with current capabilities is provided and areas for development are identified that will enable greater levels of reuse in the future. Implications and implementation challenges specific to the architecture are also presented.

  10. Laser system of extended range

    NASA Technical Reports Server (NTRS)

    Lehr, C. G.

    1972-01-01

    A pulsed laser system was developed for range measurements from the earth to retroreflecting satellites at distances up to that of the moon. The system has a transportable transmitter unit that can be moved from one location to another. This unit consists of a 0.2 m coude refractor and a high radiance, neodymium-glass, frequency doubled laser that operates in a single transverse mode. It can be used for lunar or distant satellite ranging at any observatory that has a telescope with an aperture diameter of about 1.5 m for the detection of the laser return pulses. This telescope is utilized in the same manner customarily employed for the observation of celestial objects. A special photometric package and the associated electronics are provided for laser ranging.

  11. Preliminary error budget for an optical ranging system: Range, range rate, and differenced range observables

    NASA Technical Reports Server (NTRS)

    Folkner, W. M.; Finger, M. H.

    1990-01-01

    Future missions to the outer solar system or human exploration of Mars may use telemetry systems based on optical rather than radio transmitters. Pulsed laser transmission can be used to deliver telemetry rates of about 100 kbits/sec with an efficiency of several bits for each detected photon. Navigational observables that can be derived from timing pulsed laser signals are discussed. Error budgets are presented based on nominal ground stations and spacecraft-transceiver designs. Assuming a pulsed optical uplink signal, two-way range accuracy may approach the few centimeter level imposed by the troposphere uncertainty. Angular information can be achieved from differenced one-way range using two ground stations with the accuracy limited by the length of the available baseline and by clock synchronization and troposphere errors. A method of synchronizing the ground station clocks using optical ranging measurements is presented. This could allow differenced range accuracy to reach the few centimeter troposphere limit.

  12. Culturing thick brain slices: An interstitial 3D microperfusion system for enhanced viability

    PubMed Central

    Rambani, Komal; Vukasinovic, Jelena; Glezer, Ari; Potter, Steve M.

    2009-01-01

    Brain slice preparations are well-established models for a wide spectrum of in vitro investigations in the neuroscience discipline. However, these investigations are limited to acute preparations or thin organotypic culture preparations due to the lack of a successful method that allows culturing of thick organotypic brain slices. Thick brain slice cultures suffer necrosis due to ischemia deep in the tissue resulting from a destroyed circulatory system and subsequent diffusion-limited supply of nutrients and oxygen. Although thin organotypic brain slice cultures can be successfully cultured using a well established roller tube method (a monolayer organotypic culture) (Gahwiler B H, 1981) or a membrane insert method (up to 1–4 cell layers, <150μm)(Stoppini L et al., 1991), these methods fail to support thick tissue preparations. A few perfusion methods (using submerged or interface/microfluidic chambers) have been reported to enhance the longevity (up to few hours) of acute slice preparations (up to 600μm thick) (Hass H L et al., 1979; Nicoll R A and Alger B E, 1981; Passeraub P A et al., 2003). Here, we report a unique interstitial microfluidic perfusion technique to culture thick (700μm) organotypic brain slices. The design of the custom-made micro-perfusion chamber facilitates laminar, interstitial perfusion of oxygenated nutrient medium throughout the tissue thickness with concomitant removal of depleted medium and catabolites. We examined the utility of this perfusion method to enhance the viability of the thick organotypic brain slice cultures after 2 days and 5 days in vitro (DIV). We investigated the range of amenable flow rates that enhance the viability of 700μm thick organotypic brain slices compared to the unperfused control cultures. Our perfusion method allows up to 84.6% viability (P<0.01) and up to 700μm thickness, even after 5 DIV. Our results also confirm that these cultures are functionally active and have their in vivo cytoarchitecture

  13. Short-range communication system

    NASA Technical Reports Server (NTRS)

    Alhorn, Dean C. (Inventor); Howard, David E. (Inventor); Smith, Dennis A. (Inventor)

    2012-01-01

    A short-range communication system includes an antenna, a transmitter, and a receiver. The antenna is an electrical conductor formed as a planar coil with rings thereof being uniformly spaced. The transmitter is spaced apart from the plane of the coil by a gap. An amplitude-modulated and asynchronous signal indicative of a data stream of known peak amplitude is transmitted into the gap. The receiver detects the coil's resonance and decodes same to recover the data stream.

  14. A Comparison of B16 Melanoma Cells and 3T3 Fibroblasts Concerning Cell Viability and ROS Production in the Presence of Melatonin, Tested Over a Wide Range of Concentrations.

    PubMed

    Bonmati-Carrion, Maria Angeles; Alvarez-Sánchez, Nuria; Hardeland, Rüdiger; Madrid, Juan Antonio; Rol, Maria Angeles

    2013-01-01

    Melatonin is a pleiotropic molecule with many cellular and systemic actions, including chronobiotic effects. Beneficial effects are widely documented concerning the treatment of neoplastic diseases in vivo as well as reductions in viability of cultured cells from melanoma, one of the most aggressive cancers in humans. However, studies of its effects on non-tumor cells in vitro have not focused on viability, except for experiments aiming to protect against oxidotoxicity or other toxicological insults. Furthermore, there is no agreement on the range of effective melatonin concentrations in vitro, and the mechanisms that reduce cell viability have remained unclear. Tumor cell-specific increases in the production of reactive oxygen and nitrogen species (ROS/RNS) may provide a possible explanation. Our aim was to analyze the potential inhibition of tumor (B16 melanoma 4A5) and non-tumor cell (3T3 Swiss albino) viability using a wide range of melatonin concentrations (10-11-10-2 M), and to determine whether intracellular ROS enhancement was involved in this process. In the absence of fetal bovine serum (FBS), low melatonin concentrations (10-9-10-5 M) reduced the proliferation of melanoma cells with no effect in fibroblasts, whereas, in the presence of FBS, they had no effect or even increased the proliferation of both fibroblast and melanoma cells. Melatonin concentrations in the upper millimolar range increased ROS levels and reduced the viability of both cell types, but more markedly so in non-tumor cells. Thus, low melatonin concentrations reduce proliferation in this specific melanoma cell line, whereas high concentrations affect the viability of both tumor (B16 4A5 melanoma) and non-tumor (3T3 fibroblasts) cells. Increased ROS levels in both lines indicate a role for ROS production in the reduction of cell viability at high-but not low-melatonin concentrations, although the mechanism of action still remains to be elucidated. PMID:23434670

  15. The economic viability of pursuing a space power system concept

    NASA Technical Reports Server (NTRS)

    Hazelrigg, G. A., Jr.

    1977-01-01

    The development of a space power system requires no fundamental technological breakthroughs. There are, however, uncertainties regarding the degree to which necessary developments can be achieved or exceeded. An analysis is conducted concerning the implementation of a 5000 MW space-based solar power system based on photovoltaic conversion of solar energy to electrical energy. The solar array is about 13 km long and 5 km wide. Placed in geosynchronous orbit, it provides power to the earth for 30 years. Attention is given to the economic feasibility of a space power system, a risk analysis for space power systems, and the use of the presented methodology for comparing alternative technology development programs.

  16. The Viability of Using Various System Theories to Describe Organisational Change

    ERIC Educational Resources Information Center

    Sullivan, Terence J.

    2004-01-01

    This article discusses the viability of concepts such as complex systems theory, evolutionary theory and chaos theory as metaphors for being able to give a global perspective of one particular school described in a previous article entitled "Leading people in a chaotic world." The article restates and re-explains this one particular case in…

  17. Short range miniaturized biotelemetry system

    NASA Technical Reports Server (NTRS)

    Lorenz, R.

    1975-01-01

    A biotelemetry system for measuring and transmitting EKG, EMG, and EEG data by an RF link to a receiver was designed, developed, and delivered. The system is battery operated with the batteries and transmitting electronics an integral part of the electrode sensors. The low frequency response of 0.05 Hz assures faithful reproduction of detailed EKG and all measurements are made by the utilization of two electrode sensors.

  18. Fiber optic light-scattering measurement system for evaluation of embryo viability: model experiment

    NASA Astrophysics Data System (ADS)

    Itoh, Harumi; Arai, Tsunenori; Kikuchi, Makoto

    1996-05-01

    We evaluated the particle density detectability and particle size detectivity of our fiber-optic light-scattering measurement system. In order to prevent the multiple pregnancy on current in vitro fertilization-embryo transfer, we have aimed to develop a new quantitative and non- invasive method to select a single viable human embryo. We employed the measurement of mitochondria localization in an embryo, which may have the correlation with development ability. We applied the angular distribution measurement of the light-scattering intensity from the embryo to obtain the information originated from the mitochondria. The latex spheres with a diameter of 1.0 micrometers were used to simulate the scattering intensity of the mitochondria. The measurement probes of our system consisted of two fibers for illumination and sensing. They were arranged at a right angle to a microscope optical axis to measure the angular distribution of the light-scattering intensity. We observed that the light-scattering intensity increased monotonically in the range from 106 to 1010 particles per ml. Since the mitochondria density in a human embryo corresponded to 2.5 X 107 per ml in the measurement chamber, we may measure the mitochondria density in the human embryo. The angular dependence of light-scattering intensity changed with the sphere diameters. This result showed the possibility of the selective measurement of the mitochondria density in the embryo in spite of the presence of the other cell organelle. We think that our light-scattering measurement system might be applicable to the evaluation method for the embryo viability.

  19. Short range radio locator system

    DOEpatents

    McEwan, T.E.

    1996-12-31

    A radio location system comprises a wireless transmitter that outputs two megahertz period bursts of two gigahertz radar carrier signals. A receiver system determines the position of the transmitter by the relative arrival of the radar bursts at several component receivers set up to have a favorable geometry and each one having a known location. One receiver provides a synchronizing gating pulse to itself and all the other receivers. The rate of the synchronizing gating pulse is slightly offset from the rate of the radar bursts themselves, so that each sample collects one finely-detailed piece of information about the time-of-flight of the radar pulse to each receiver each pulse period. Thousands of sequential pulse periods provide corresponding thousand of pieces of information about the time-of-flight of the radar pulse to each receiver, in expanded, not real time. Therefore the signal processing can be done with relatively low-frequency, inexpensive components. A conventional microcomputer is then used to find the position of the transmitter by geometric triangulation based on the relative time-of-flight information. 5 figs.

  20. Short range radio locator system

    DOEpatents

    McEwan, Thomas E.

    1996-01-01

    A radio location system comprises a wireless transmitter that outputs two megahertz period bursts of two gigahertz radar carrier signals. A receiver system determines the position of the transmitter by the relative arrival of the radar bursts at several component receivers set up to have a favorable geometry and each one having a known location. One receiver provides a synchronizing gating pulse to itself and all the other receivers to sample the ether for the radar pulse. The rate of the synchronizing gating pulse is slightly offset from the rate of the radar bursts themselves, so that each sample collects one finely-detailed piece of information about the time-of-flight of the radar pulse to each receiver each pulse period. Thousands of sequential pulse periods provide corresponding thousand of pieces of information about the time-of-flight of the radar pulse to each receiver, in expanded, not real time. Therefore the signal processing can be done with relatively low-frequency, inexpensive components. A conventional microcomputer is then used to find the position of the transmitter by geometric triangulation based on the relative time-of-flight information.

  1. CO2 laser ranging systems study

    NASA Technical Reports Server (NTRS)

    Filippi, C. A.

    1975-01-01

    The conceptual design and error performance of a CO2 laser ranging system are analyzed. Ranging signal and subsystem processing alternatives are identified, and their comprehensive evaluation yields preferred candidate solutions which are analyzed to derive range and range rate error contributions. The performance results are presented in the form of extensive tables and figures which identify the ranging accuracy compromises as a function of the key system design parameters and subsystem performance indexes. The ranging errors obtained are noted to be within the high accuracy requirements of existing NASA/GSFC missions with a proper system design.

  2. The Geoscience Laser Altimetry/Ranging System

    NASA Technical Reports Server (NTRS)

    Cohen, Steven C.; Degnan, John J., III; Bufton, Jack L.; Garvin, James B.; Abshire, James B.

    1987-01-01

    The Geoscience Laser Altimetry/Ranging System (GLARS), a combined laser ranging and altimetry system capable of subcentimeter position determinations of retroflector targets and subdecimeter profiling of topography, is described. The system uses advanced but currently available state-of-the-art components. Laboratory, field, and numerical experiments have indicated the suitability of GLARS as an instrument for Eos and other space platforms.

  3. Preserving viability of Lactobacillus rhamnosus GG in vitro and in vivo by a new encapsulation system

    PubMed Central

    Li, Ran; Zhang, Yufeng; Polk, D. Brent; Tomasula, Peggy M.; Yan, Fang; Liu, LinShu

    2016-01-01

    Probiotics have shown beneficial effects on health and prevention of diseases in humans. However, a concern for application of probiotics is the loss of viability during storage and gastrointestinal transit. The aim of this study was to develop an encapsulation system to preserve viability of probiotics when they are administrated orally and apply Lactobacillus rhamnosus GG (LGG) as a probiotic model to evaluate the effectiveness of this approach using in vitro and in vivo experiments. LGG was encapsulated in hydrogel beads prepared using pectin, a food grade polysaccharide, glucose, and calcium chloride, and lyophilized by freeze-drying. Encapsulated LGG was cultured in vitro under the condition that mimicked the physiological environment of the human gastrointestinal tract. Compared to non-encapsulated LGG, encapsulation increased tolerance of LGG in the acid condition, protected LGG from protease digestion, and improved shelf time when stored at the ambient condition, in regard of survivability and production of p40, a known LGG-derived protein involved in LGG’s beneficial effects on intestinal homeostasis. To evaluate the effects of encapsulation on p40 production in vivo and prevention of intestinal inflammation by LGG, mice were gavaged with LGG containing beads and treated with dextran sulphate sodium (DSS) to induce intestinal injury and colitis. Compared to non-encapsulated LGG, encapsulated LGG enhanced more p40 production in mice, and exerted higher levels of effects on prevention of DSS-induced colonic injury and colitis and suppression of pro-inflammatory cytokine production. These data indicated that the encapsulation system developed in this study preserves viability of LGG in vitro and in vivo, leading to longer shelf time and enhancing the functions of LGG in the gastrointestinal tract. Thus, this encapsulation approach may have the potential application for improving efficacy of probiotics. PMID:27063422

  4. Preserving viability of Lactobacillus rhamnosus GG in vitro and in vivo by a new encapsulation system.

    PubMed

    Li, Ran; Zhang, Yufeng; Polk, D Brent; Tomasula, Peggy M; Yan, Fang; Liu, LinShu

    2016-05-28

    Probiotics have shown beneficial effects on health and prevention of diseases in humans. However, a concern for application of probiotics is the loss of viability during storage and gastrointestinal transit. The aim of this study was to develop an encapsulation system to preserve viability of probiotics when they are administrated orally and apply Lactobacillus rhamnosus GG (LGG) as a probiotic model to evaluate the effectiveness of this approach using in vitro and in vivo experiments. LGG was encapsulated in hydrogel beads prepared using pectin, a food grade polysaccharide, glucose, and calcium chloride, and lyophilized by freeze-drying. Encapsulated LGG was cultured in vitro under the condition that mimicked the physiological environment of the human gastrointestinal tract. Compared to non-encapsulated LGG, encapsulation increased tolerance of LGG in the acid condition, protected LGG from protease digestion, and improved shelf time when stored at the ambient condition, in regard of survivability and production of p40, a known LGG-derived protein involved in LGG's beneficial effects on intestinal homeostasis. To evaluate the effects of encapsulation on p40 production in vivo and prevention of intestinal inflammation by LGG, mice were gavaged with LGG containing beads and treated with dextran sulphate sodium (DSS) to induce intestinal injury and colitis. Compared to non-encapsulated LGG, encapsulated LGG enhanced more p40 production in mice, and exerted higher levels of effects on prevention of DSS-induced colonic injury and colitis and suppression of pro-inflammatory cytokine production. These data indicated that the encapsulation system developed in this study preserves viability of LGG in vitro and in vivo, leading to longer shelf time and enhancing the functions of LGG in the gastrointestinal tract. Thus, this encapsulation approach may have the potential application for improving efficacy of probiotics. PMID:27063422

  5. Monitoring of cell viability and proliferation in hydrogel-encapsulated system by resazurin assay.

    PubMed

    Xiao, Jing; Zhang, Ying; Wang, Jianzheng; Yu, Weiting; Wang, Wei; Ma, Xiaojun

    2010-11-01

    Cell microencapsulation is a promising approach for cell implantation, cell-based gene therapy and large-scale cell culture. For better quality control, it is important to accurately measure the microencapsulated cell viability and proliferation in the culture. A number of assays have been used for this purpose, but limitations arise. In this study, we investigated the feasibility and reliability of resazurin as a cell growth indicator in microencapsulated culture system. According to the experiment data, there was a reversible, time- and dose-dependent growth inhibition as observed for resazurin application in encapsulated cells. A positive relationship was observed between reduction of resazurin and CHO cell number in microcapsule. Moreover, the resazurin assay provided an equivalent result to the commonly used MTT method in determining CHO cell proliferation in APA microcapsule with no notable influence on cell distribution and organization pattern. In conclusion, resazurin assay is offered as a simple, rapid and non-invasive method for in vitro microencapsulated cell viability and proliferation measurement. PMID:20437208

  6. Laser Doppler And Range Systems For Spacecraft

    NASA Technical Reports Server (NTRS)

    Kinman, P. W.; Gagliardi, R. M.

    1990-01-01

    Report discusses two types of proposed laser systems containing active transponders measuring distance (range) and line-of-sight velocity (via Doppler effect) between deep space vehicle and earth-orbiting satellite. Laser system offers diffraction advantage over microwave system. Delivers comparable power to distant receiver while using smaller transmitting and receiving antennas and less-powerful transmitter. Less subject to phase scintillations caused by passage through such inhomogeneous media as solar corona. One type of system called "incoherent" because range and Doppler measurements do not require coherence with laser carrier signals. Other type of system called "coherent" because successful operation requires coherent tracking of laser signals.

  7. [Viability of the hospital system in Catalonia [Spain]. Balance after a decade].

    PubMed

    Cots, Francesc

    2004-01-01

    Concern about the viability of the hospital system has increased as demand has continued to grow and as the expected increase in public resources to meet this demand remains below requirements. The Central de Balances of CatSalut, which groups all the economic results of the Catalan Public Hospital Network (CPHN), has enabled determination of the relationship between activity and resources in the hospitals within the public sector from 1993 to 2000. We analyzed data from the Central de Balances to determine hospital functioning throughout the 1990s, paying special attention to the development of the hospital system's general productivity over this period. The annual accumulative growth in activity was 4.1%, that of expenses was 1.8% and that of revenues was 1.9%. Unitary cost in 2000 was 85.3% of the unitary cost in 1993. PMID:14980175

  8. Programmable near-infrared ranging system

    DOEpatents

    Everett, Jr., Hobart R.

    1989-01-01

    A high angular resolution ranging system particularly suitable for indoor plications involving mobile robot navigation and collision avoidance uses a programmable array of light emitters that can be sequentially incremented by a microprocessor. A plurality of adjustable level threshold detectors are used in an optical receiver for detecting the threshold level of the light echoes produced when light emitted from one or more of the emitters is reflected by a target or object in the scan path of the ranging system.

  9. Study on short distance laser ranging system

    NASA Astrophysics Data System (ADS)

    Bao, Jianan; Li, Jicheng; Zhang, Cong

    2015-02-01

    Laser ranging technology is an industrial non contact measuring technology. With the rapidly development of electronics and optical technology, the measuring precision has been improved continuously. In this paper, a simple structure measuring system which based on laser triangulation measuring theory, was built. The system consist of single point laser and CMOS receiver, its measuring range is from 90mm to 110mm. In order to get a higher position accuracy of light spot, gauss cumulative method was used in this paper. For realize the precision system calibration, a linear calibration method was introduced. The experiment shows that the system get a measuring precision of 10um.

  10. Trilateration range and range rate system. Volume 1: CDA system manual

    NASA Technical Reports Server (NTRS)

    1976-01-01

    This document is one of a series of manuals designed to provide the information required to operate and maintain the Command and Data Acquisition (CDA) equipment of the Trilateration Range and Range Rate (TRRR) System. Information pertaining to the equipment in the Trilateration Range and Range Rate System which is designed to interface with existing NASA equipment located at Wallops Island, Virginia is presented.

  11. Dynamic assessment of cell viability, proliferation and migration using real time cell analyzer system (RTCA).

    PubMed

    Roshan Moniri, Mani; Young, Ada; Reinheimer, Kelsey; Rayat, Jarrett; Dai, Long-Jun; Warnock, Garth L

    2015-03-01

    Cell viability and cell migration capacities are critical parameters for cell culture-related studies. It is essential to monitor the dynamic changes of cell properties under various co-culture conditions to our better understanding of their behaviours and characteristics. The real time cell analyzer (RTCA, xCELLigence, Roche) is an impedance-based technology that can be used for label-free and real-time monitoring of cell properties, such as cell adherence, proliferation, migration and cytotoxicity. The practicality of this system has been proven in our recent cancer studies. In the present method, we intend to use co-cultures of pancreatic cancer cells (HP62) and mesenchymal stem cells to describe in detail, the procedures and benefits of RTCA. PMID:24443077

  12. Ultra High Mass Range Mass Spectrometer System

    DOEpatents

    Reilly, Peter T. A. [Knoxville, TN

    2005-12-06

    Applicant's present invention comprises mass spectrometer systems that operate in a mass range from 1 to 10.sup.16 DA. The mass spectrometer system comprising an inlet system comprising an aerodynamic lens system, a reverse jet being a gas flux generated in an annulus moving in a reverse direction and a multipole ion guide; a digital ion trap; and a thermal vaporization/ionization detector system. Applicant's present invention further comprises a quadrupole mass spectrometer system comprising an inlet system having a quadrupole mass filter and a thermal vaporization/ionization detector system. Applicant's present invention further comprises an inlet system for use with a mass spectrometer system, a method for slowing energetic particles using an inlet system. Applicant's present invention also comprises a detector device and a method for detecting high mass charged particles.

  13. Transponder System for High-Frequency Ranging

    NASA Technical Reports Server (NTRS)

    Lichtenberg, C. L.; Shores, P. W.; Kobayashi, H. S.

    1986-01-01

    Transponder system uses phase difference between transmitted and reflected high-frequency radio waves to measure distance to target. To suppress spurious measurements of reflections from objects near target at transmitted frequency and its harmonics, transponder at target generates return signal at half transmitted frequency. System useful in such applications as surveying, docking of ships, and short-range navigation.

  14. Automatic laser tracking and ranging system.

    PubMed

    Cooke, C R

    1972-02-01

    An automatic laser tracking and ranging system has been developed for use with cooperative retroreflective targets. Target position is determined with high precision at ranges out to 19 km and sample rates up to one hundred measurements per second. The data are recorded on a magnetic tape in the form of azimuth, elevation, range, and standard time and are computer-compatible. The system is fully automatic with the exception of the initial acquisition sequence, which is performed manually. This eliminates the need for expensive and time-consuming photographic data reduction. Also, position is uniquely determined by a single instrument. To provide convenient operation at remote sites, the system is van-mounted and operates off a portable power generator. The transmitter is a flash-pumped Q-spoiled Nd:YAG laser developing 1 MW peak power in a 10-mrad beam at a rate of 100 pps. The beam, which is coaxial with the receiver, is directed to the target by an azimuth-elevation mirror mount. The return beam is imaged o separate ranging and tracking receivers. The ranging receiver measures time of flight of the 25-nsec laser pulse with range accuracies of +/-15 cm. The tracking receiver uses a quadrant photodiode followed by matched log video amplifiers and achieves a tracking accuracy of +/-0.1 mrad. An optical dynamic range of 30 dB is provided to minimize error due to scintillation. Also, 80 dB of optical dynamic range is provided by adjustable neutral density filters to compensate for changes in target range. PMID:20111495

  15. Viability of decision-making systems in human and animal groups.

    PubMed

    Sueur, Cédric

    2012-08-01

    Shared and unshared consensuses are present in both human and animal societies. To date, few studies have applied an evolutionary perspective to the viability of these systems. This study therefore aimed to assess if decision-making allows group members to satisfy all their needs and to survive, decision after decision, day after day. The novelty of this study is the inclusion of multiple decision-making events with varying conditions and the parameterization of the model based on data in macaques, bringing the model closer to ecologically reality. The activity budgets of group members in the model did not differ significantly from those observed in macaques, making the model robust and providing mechanistic insight. Three different decision-making systems were then tested: (1) One single leader, (2) Leading according to needs and (3) Voting process. Results show that when individuals have equal needs, all decision-making systems are viable. However, one single leader cannot impose its decision when the needs of other group members differ too much from its own needs. The leading according to needs system is always viable whatever the group heterogeneity. However, the individual with the highest body mass decides in the majority of cases. Finally, the voting process also appears to be viable, with a majority threshold that differs according to group size and to different individual needs. This study is the first clear prediction of the different types of consensus in animal groups used in various different conditions. PMID:22554449

  16. ROA's Real time GNSS network and its viability in Alertes-RIM system

    NASA Astrophysics Data System (ADS)

    Cibeira Urtiaga, Ángel; Gárate, Jorge; Mendoza, Leonor

    2015-04-01

    San Fernando Naval Observatory deployed a Geodetic Continuous GNSS network from the mid nineties. The most of the sites are located in the South of the Iberian Peninsula. Nowadays time series of several years for the most of these sites are available. This is the most risky region in the peninsula due to the confrontation of two tectonic plates, i.e. Euro-Asiatic and African Plates. The former confrontation generated several faults, origin of important earthquakes (e.g. the big earthquake of Lisbon in 1775, whose epicenter was located in the Azores-Gibraltar fault, where Euro-Asiatic and African plates collide). In order to prevent higher aftermaths, the San Fernando Naval Observatory with the University of Cádiz and the University Complutense of Madrid, started to develop an early warning system, based on the study of the P waves, with the result of a prototype known as Alertes system. In early 2014 an improvement of the Alertes-RIM system began, introducing the study of viability of using high frequency geodetic GNSS signals in real time and others, looking for an improvement in the time of response in the previous instants of an earthquake. This project is still on process of development.

  17. Demonstration of high sensitivity laser ranging system

    NASA Technical Reports Server (NTRS)

    Millar, Pamela S.; Christian, Kent D.; Field, Christopher T.

    1994-01-01

    We report on a high sensitivity semiconductor laser ranging system developed for the Gravity and Magnetic Earth Surveyor (GAMES) for measuring variations in the planet's gravity field. The GAMES laser ranging instrument (LRI) consists of a pair of co-orbiting satellites, one which contains the laser transmitter and receiver and one with a passive retro-reflector mounted in an drag-stabilized housing. The LRI will range up to 200 km in space to the retro-reflector satellite. As the spacecraft pair pass over the spatial variations in the gravity field, they experience along-track accelerations which change their relative velocity. These time displaced velocity changes are sensed by the LRI with a resolution of 20-50 microns/sec. In addition, the pair may at any given time be drifting together or apart at a rate of up to 1 m/sec, introducing a Doppler shift into the ranging signals. An AlGaAs laser transmitter intensity modulated at 2 GHz and 10 MHz is used as fine and medium ranging channels. Range is measured by comparing phase difference between the transmit and received signals at each frequency. A separate laser modulated with a digital code, not reported in this paper, will be used for coarse ranging to unambiguously determine the distance up to 200 km.

  18. Global positioning system missile test range applications

    SciTech Connect

    Partridge, M.E.

    1986-06-01

    Using the Global Positioning System (GPS), a missile under test could transmit its own position, reducing radar tracking requirements while still providing three-dimensional position and velocity data with the required accuracy. This study investigated minimum package size requirements for GPS implementation on the SRAM II missile as part of the joint test assembly telemetry system. Reported GPS missile test range applications are reviewed. The two missile tracking system implementations considered are a complete GPS package onboard the missile and onboard frequency translator that retransmits the GPS satellite signals. Accuracy and operation of the two methods are compared. A functional description of the GPS is provided.

  19. Geothermal systems of the Cascade Range

    USGS Publications Warehouse

    Muffler, L.J.; Bacon, Charles R.; Duffield, W.A.

    1982-01-01

    In the central and southern Cascade Range, plate convergence is oblique, and Quaternary volcanism produces mostly basalt and mafic andesite; large andesite-dacite composite volcanoes and silicic dome fields occur in restricted areas of long-lived igneous activity. To the north, plate convergence is normal, producing widely spaced centers in which mafic lavas are minor. Most Cascade volcanoes are short-lived and unlikely to be underlain at shallow levels by large magma bodies that could support high-temperature geothermal systems. Such systems are known, however, near Meager Mountain, at Newberry Volcano, and near Lassen Peak. Persistent fumaroles occur on several major composite volcanoes, but drilling to date has been insufficient to determine whether exploitable geothermal reservoirs occur at depth. Thermal springs away from the major volcanic centers are few and generally inconspicuous. However, significant geothermal systems along and west of the Cascade Range may well be masked by abundant cold ground water.

  20. Atmospheric refraction errors in laser ranging systems

    NASA Technical Reports Server (NTRS)

    Gardner, C. S.; Rowlett, J. R.

    1976-01-01

    The effects of horizontal refractivity gradients on the accuracy of laser ranging systems were investigated by ray tracing through three dimensional refractivity profiles. The profiles were generated by performing a multiple regression on measurements from seven or eight radiosondes, using a refractivity model which provided for both linear and quadratic variations in the horizontal direction. The range correction due to horizontal gradients was found to be an approximately sinusoidal function of azimuth having a minimum near 0 deg azimuth and a maximum near 180 deg azimuth. The peak to peak variation was approximately 5 centimeters at 10 deg elevation and decreased to less than 1 millimeter at 80 deg elevation.

  1. Comparison of the Copan eSwab System with an Agar Swab Transport System for Maintenance of Fastidious Anaerobic Bacterium Viability

    PubMed Central

    Citron, Diane M.; Leoncio, Eliza S.; Goldstein, Ellie J. C.

    2016-01-01

    We compared the eSwab system to a swab with an anaerobic transport semisolid agar system for their capacities to maintain the viability of 20 species of fastidious anaerobes inoculated on the bench and held at ambient or refrigerator temperature for 24 or 48 h. On average, both systems maintained similar viabilities among analogous groups of organisms at both temperatures, although there were quantitative differences among some species. PMID:26888906

  2. Comparison of the Copan eSwab System with an Agar Swab Transport System for Maintenance of Fastidious Anaerobic Bacterium Viability.

    PubMed

    Tyrrell, Kerin L; Citron, Diane M; Leoncio, Eliza S; Goldstein, Ellie J C

    2016-05-01

    We compared the eSwab system to a swab with an anaerobic transport semisolid agar system for their capacities to maintain the viability of 20 species of fastidious anaerobes inoculated on the bench and held at ambient or refrigerator temperature for 24 or 48 h. On average, both systems maintained similar viabilities among analogous groups of organisms at both temperatures, although there were quantitative differences among some species. PMID:26888906

  3. Initiative for Future Agricultural Food Systems (IFAFS) From Farm to School: Improving Small Farm Viability and School Meals

    ERIC Educational Resources Information Center

    Kish, Stacy

    2008-01-01

    Improving the nutritional value of school meals is a growing priority among school systems across the United States. To assist in this effort, the USDA's Cooperative State Research, Education, and Extension Service (CSREES) funded a coalition, which developed a new program called "From Farm to School: Improving Small Farm Viability and School…

  4. Utilization and viability of biologically-inspired algorithms in a dynamic multiagent camera surveillance system

    NASA Astrophysics Data System (ADS)

    Mundhenk, Terrell N.; Dhavale, Nitin; Marmol, Salvador; Calleja, Elizabeth; Navalpakkam, Vidhya; Bellman, Kirstie; Landauer, Chris; Arbib, Michael A.; Itti, Laurent

    2003-10-01

    computational resources. The system demonstrates the viability of biologically inspired systems in a real time tracking. In future work we plan on implementing additional biological mechanisms for cooperative management of both the sensor and processing resources in this system that include top down biasing for target specificity as well as novelty and the activity of the tracked object in relation to sensitive features of the environment.

  5. Long range position and Orientation Tracking System

    SciTech Connect

    Armstrong, G.A.; Jansen, J.F.; Burks, B.L.

    1996-02-01

    The long range Position and Orientation Tracking System is an active triangulation-based system that is being developed to track a target to a resolution of 6.35 mm (0.25 in.) and 0.009{degrees}(32.4 arcseconds) over a range of 13.72 m (45 ft.). The system update rate is currently set at 20 Hz but can be increased to 100 Hz or more. The tracking is accomplished by sweeping two pairs of orthogonal line lasers over infrared (IR) sensors spaced with known geometry with respect to one another on the target (the target being a rigid body attached to either a remote vehicle or a remote manipulator arm). The synchronization and data acquisition electronics correlates the time that an IR sensor has been hit by one of the four lasers and the angle of the respective mirror at the time of the hit. This information is combined with the known geometry of the IR sensors on the target to determine position and orientation of the target. This method has the advantage of allowing the target to be momentarily lost due to occlusions and then reacquired without having to return the target to a known reference point. The system also contains a camera with operator controlled lighting in each pod that allows the target to be continuously viewed from either pod, assuming their are no occlusions.

  6. The Potential of Energy Storage Systems with Respect to Generation Adequacy and Economic Viability

    NASA Astrophysics Data System (ADS)

    Bradbury, Kyle Joseph

    Intermittent energy resources, including wind and solar power, continue to be rapidly added to the generation fleet domestically and abroad. The variable power of these resources introduces new levels of stochasticity into electric interconnections that must be continuously balanced in order to maintain system reliability. Energy storage systems (ESSs) offer one potential option to compensate for the intermittency of renewables. ESSs for long-term storage (1-hour or greater), aside from a few pumped hydroelectric installations, are not presently in widespread use in the U.S. The deployment of ESSs would be most likely driven by either the potential for a strong internal rate of return (IRR) on investment and through significant benefits to system reliability that independent system operators (ISOs) could incentivize. To assess the potential of ESSs three objectives are addressed. (1) Evaluate the economic viability of energy storage for price arbitrage in real-time energy markets and determine system cost improvements for ESSs to become attractive investments. (2) Estimate the reliability impact of energy storage systems on the large-scale integration of intermittent generation. (3) Analyze the economic, environmental, and reliability tradeoffs associated with using energy storage in conjunction with stochastic generation. First, using real-time energy market price data from seven markets across the U.S. and the physical parameters of fourteen ESS technologies, the maximum potential IRR of each technology from price arbitrage was evaluated in each market, along with the optimal ESS system size. Additionally, the reductions in capital cost needed to achieve a 10% IRR were estimated for each ESS. The results indicate that the profit-maximizing size of an ESS is primarily determined by its technological characteristics (round-trip charge/discharge efficiency and self-discharge) and not market price volatility, which instead increases IRR. This analysis demonstrates

  7. Geodynamic laser ranging system laser transmitter

    NASA Technical Reports Server (NTRS)

    Dallas, J. L.; Czechanski, J. P.; Coyle, D. B.; Zukowski, B. J.; Seery, B. D.

    1991-01-01

    A description is given of the requirements and design options in the development of a spaceborne laser transmitter for NASA's Geodynamic Laser Ranging System. Three different oscillators are considered. The first is an injection-seeded ring oscillator yielding 1 mJ of energy within a 120-ps pulse. The second is a frequency-modulated mode-locked oscillator emitting 0.30 nJ in a 20-ps pulse. The third is a self-starting, additive pulse mode-locked laser. Detailed design considerations and preliminary results of these lasers are reported as well as the design of a unique multipass amplifier.

  8. Long range position and orientation tracking system

    SciTech Connect

    Armstrong, G.A.; Jansen, J.F.; Burks, B.L.; Bernacki, B.E.; Nypaver, D.J.

    1995-12-31

    The long range position and orientation tracking system (LRPOTS) will consist of two measurement pods, a VME-based computer system, and a detector array. The system is used to measure the position and orientation of a target that may be attached to a robotic arm, teleoperated manipulator, or autonomous vehicle. The pods have been designed to be mounted in the man-ways of the domes of the Fernald K-65 waste silos. Each pod has two laser scanner subsystems as well as lights and camera systems. One of the laser scanners will be oriented to scan in the pan direction, the other in the tilt direction. As the lasers scan across the detector array, the angles of incidence with each detector are recorded. Combining measurements from each of the four lasers yields sufficient data for a closed-form solution of the transform describing the location and orientation of the Content Mobilization System (CMS). Redundant detectors will be placed on the CMS to accommodate occlusions, to provide improved measurement accuracy, and to determine the CMS orientation.

  9. Ultrasonic ranging and data telemetry system

    DOEpatents

    Brashear, Hugh R.; Blair, Michael S.; Phelps, James E.; Bauer, Martin L.; Nowlin, Charles H.

    1990-01-01

    An ultrasonic ranging and data telemetry system determines a surveyor's position and automatically links it with other simultaneously taken survey data. An ultrasonic and radio frequency (rf) transmitter are carried by the surveyor in a backpack. The surveyor's position is determined by calculations that use the measured transmission times of an airborne ultrasonic pulse transmitted from the backpack to two or more prepositioned ultrasonic transceivers. Once a second, rf communications are used both to synchronize the ultrasonic pulse transmission-time measurements and to transmit other simultaneously taken survey data. The rf communications are interpreted by a portable receiver and microcomputer which are brought to the property site. A video display attached to the computer provides real-time visual monitoring of the survey progress and site coverage.

  10. REDEX - The ranging equipment diagnostic expert system

    NASA Technical Reports Server (NTRS)

    Luczak, Edward C.; Gopalakrishnan, K.; Zillig, David J.

    1989-01-01

    REDEX, an advanced prototype expert system that diagnoses hardware failures in the Ranging Equipment (RE) at NASA's Ground Network tracking stations is described. REDEX will help the RE technician identify faulty circuit cards or modules that must be replaced, and thereby reduce troubleshooting time. It features a highly graphical user interface that uses color block diagrams and layout diagrams to illustrate the location of a fault. A semantic network knowledge representation technique was used to model the design structure of the RE. A catalog of generic troubleshooting rules was compiled to represent heuristics that are applied in diagnosing electronic equipment. Specific troubleshooting rules were identified to represent additional diagnostic knowledge that is unique to the RE. Over 50 generic and 250 specific troubleshooting rules have been derived. REDEX is implemented in Prolog on an IBM PC AT-compatible workstation. Block diagram graphics displays are color-coded to identify signals that have been monitored or inferred to have nominal values, signals that are out of tolerance, and circuit cards and functions that are diagnosed as faulty. A hypertext-like scheme is used to allow the user to easily navigate through the space of diagrams and tables. Over 50 graphic and tabular displays have been implemented. REDEX is currently being evaluated in a stand-alone mode using simulated RE fault scenarios. It will soon be interfaced to the RE and tested in an online environment. When completed and fielded, REDEX will be a concrete example of the application of expert systems technology to the problem of improving performance and reducing the lifecycle costs of operating NASA's communications networks in the 1990s.

  11. REDEX: The ranging equipment diagnostic expert system

    NASA Technical Reports Server (NTRS)

    Luczak, Edward C.; Gopalakrishnan, K.; Zillig, David J.

    1989-01-01

    REDEX, an advanced prototype expert system that diagnoses hardware failures in the Ranging Equipment (RE) at NASA's Ground Network tracking stations is described. REDEX will help the RE technician identify faulty circuit cards or modules that must be replaced, and thereby reduce troubleshooting time. It features a highly graphical user interface that uses color block diagrams and layout diagrams to illustrate the location of a fault. A semantic network knowledge representation technique was used to model the design structure of the RE. A catalog of generic troubleshooting rules was compiled to represent heuristics that are applied in diagnosing electronic equipment. Specific troubleshooting rules were identified to represent additional diagnostic knowledge that is unique to the RE. Over 50 generic and 250 specific troubleshooting rules have been derived. REDEX is implemented in Prolog on an IBM PC AT-compatible workstation. Block diagram graphics displays are color-coded to identify signals that have been monitored or inferred to have nominal values, signals that are out of tolerance, and circuit cards and functions that are diagnosed as faulty. A hypertext-like scheme is used to allow the user to easily navigate through the space of diagrams and tables. Over 50 graphic and tabular displays have been implemented. REDEX is currently being evaluated in a stand-alone mode using simulated RE fault scenarios. It will soon be interfaced to the RE and tested in an online environment. When completed and fielded, REDEX will be a concrete example of the application of expert systems technology to the problem of improving performance and reducing the lifecycle costs of operating NASA's communications networks in the 1990's.

  12. Economic viability and critical influencing factors assessment of black water and grey water source-separation sanitation system.

    PubMed

    Thibodeau, C; Monette, F; Glaus, M; Laflamme, C B

    2011-01-01

    The black water and grey water source-separation sanitation system aims at efficient use of energy (biogas), water and nutrients but currently lacks evidence of economic viability to be considered a credible alternative to the conventional system. This study intends to demonstrate economic viability, identify main cost contributors and assess critical influencing factors. A technico-economic model was built based on a new neighbourhood in a Canadian context. Three implementation scales of source-separation system are defined: 500, 5,000 and 50,000 inhabitants. The results show that the source-separation system is 33% to 118% more costly than the conventional system, with the larger cost differential obtained by lower source-separation system implementation scales. A sensitivity analysis demonstrates that vacuum toilet flow reduction from 1.0 to 0.25 L/flush decreases source-separation system cost between 23 and 27%. It also shows that high resource costs can be beneficial or unfavourable to the source-separation system depending on whether the vacuum toilet flow is low or normal. Therefore, the future of this configuration of the source-separation system lies mainly in vacuum toilet flow reduction or the introduction of new efficient effluent volume reduction processes (e.g. reverse osmosis). PMID:22170836

  13. Laser System for Precise, Unambiguous Range Measurements

    NASA Technical Reports Server (NTRS)

    Dubovitsky, Serge; Lay, Oliver

    2005-01-01

    The Modulation Sideband Technology for Absolute Range (MSTAR) architecture is the basis of design of a proposed laser-based heterodyne interferometer that could measure a range (distance) as great as 100 km with a precision and resolution of the order of 1 nm. Simple optical interferometers can measure changes in range with nanometer resolution, but cannot measure range itself because interference is subject to the well-known integer-multiple-of-2 -radians phase ambiguity, which amounts to a range ambiguity of the order of 1 m at typical laser wavelengths. Existing rangefinders have a resolution of the order of 10 m and are therefore unable to resolve the ambiguity. The proposed MSTAR architecture bridges the gap, enabling nanometer resolution with an ambiguity range that can be extended to arbitrarily large distances. The MSTAR architecture combines the principle of the heterodyne interferometer with the principle of extending the ambiguity range of an interferometer by using light of two wavelengths. The use of two wavelengths for this purpose is well established in optical metrology, radar, and sonar. However, unlike in traditional two-color laser interferometry, light of two wavelengths would not be generated by two lasers. Instead, multiple wavelengths would be generated as sidebands of phase modulation of the light from a single frequency- stabilized laser. The phase modulation would be effected by applying sinusoidal signals of suitable frequencies (typically tens of gigahertz) to high-speed electro-optical phase modulators. Intensity modulation can also be used

  14. Ranging/tracking system for proximity operations

    NASA Technical Reports Server (NTRS)

    Nilsen, P.; Udalov, S.

    1982-01-01

    The hardware development and testing phase of a hand held radar for the ranging and tracking for Shuttle proximity operations are considered. The radar is to measure range to a 3 sigma accuracy of 1 m (3.28 ft) to a maximum range of 1850 m (6000 ft) and velocity to a 3 sigma accuracy of 0.03 m/s (0.1 ft/s). Size and weight are similar to hand held radars, frequently seen in use by motorcycle police officers. Meeting these goals for a target in free space was very difficult to obtain in the testing program; however, at a range of approximately 700 m, the 3 sigma range error was found to be 0.96 m. It is felt that much of this error is due to clutter in the test environment. As an example of the velocity accuracy, at a range of 450 m, a 3 sigma velocity error of 0.02 m/s was measured. The principles of the radar and recommended changes to its design are given. Analyses performed in support of the design process, the actual circuit diagrams, and the software listing are included.

  15. Irradiation Can Selectively Kill Tumor Cells while Preserving Erythrocyte Viability in a Co-Culture System

    PubMed Central

    Liu, Yun-Qing; Tang, Li-Hui; Wang, Yin; Wang, Lie-Ju; Zhang, Feng-Jiang; Yan, Min

    2015-01-01

    An understanding of how to safely apply intraoperative blood salvage (IBS) in cancer surgery has not yet been obtained. Here, we investigated the optimal dose of 137Cs gamma-ray irradiation for killing human hepatocarcinoma (HepG2), gastrocarcinoma (SGC7901), and colonic carcinoma (SW620) tumor cells while preserving co-cultured erythrocytes obtained from 14 healthy adult volunteers. HepG2, SGC7901, or SW620 cells were mixed into the aliquots of erythrocytes. After the mixed cells were treated with 137Cs gamma-ray irradiation (30, 50, and 100 Gy), tumor cells and erythrocytes were separated by density gradient centrifugation in Percoll with a density of 1.063 g/ml. The viability, clonogenicity, DNA synthesis, tumorigenicity, and apoptosis of the tumor cells were determined by MTT assay, plate colony formation, 5-ethynyl-2'-deoxyuridine (EdU) incorporation, subcutaneous xenograft implantation into immunocompromised mice, and annexin V/7-AAD staining, respectively. The ATP concentration, 2,3-DPG level, free Hb concentration, osmotic fragility, membrane phosphatidylserine externalization, blood gas variables, reactive oxygen species levels, and superoxide dismutase levels in erythrocytes were analyzed. We found that 137Cs gamma-ray irradiation at 50 Gy effectively inhibited the viability, proliferation, and tumorigenicity of HepG2, SGC7901, and SW620 cells without markedly damaging the oxygen-carrying ability or membrane integrity or increasing the oxidative stress of erythrocytes in vitro. These results demonstrated that 50 Gy irradiation in a standard 137Cs blood irradiator might be a safe and effective method of inactivating HepG2, SGC7901, and SW620 cells mixed with erythrocytes, which might help to safely allow IBS in cancer surgery. PMID:26018651

  16. SYSTEM FOR AND METHOD OF DETERMINING RANGE

    DOEpatents

    Horrell, M.W.; Sanders, E.R.

    1963-11-01

    A system and method for indicating a predetermined altitude of an object or aircraft is described. The device utilizes a pulse transmit-receive system wherein pulses of predetermined width are transmitted towards the ground and the reflected pulses received gating only pulses having a predetermined width. (AEC)

  17. The cybernetics of viability: an overview

    NASA Astrophysics Data System (ADS)

    Nechansky, Helmut

    2011-10-01

    A three-level approach to viability is developed, considering (1) living systems, (2) a niche, understood as the area within the reach of their actions, and (3) an environment. A systematic analysis of the interrelations between these levels shows that living systems emerge with matter/energy processing systems. These can add controller structures when producing excess energy. A three-sensor controller structure enables a living system to deal with unfavourable and scarce environments. Further evolution of these controller structures offers improved ways to act on niches. Maintaining niches in scarce environments can require technology or economy. So social systems emerge, which are understood as aggregates of living systems. Basic patterns of interactions within social systems are analysed. So the introduction of the notion of the niche into the discussion of viability allows us to explain phenomena ranging from properties of single living systems to societal organization.

  18. Long-range interaction of anisotropic systems

    NASA Astrophysics Data System (ADS)

    Zhang, J.-Y.; Schwingenschlögl, U.

    2015-02-01

    The first-order electrostatic interaction energy between two far-apart anisotropic atoms depends not only on the distance between them but also on their relative orientation, according to Rayleigh-Schrödinger perturbation theory. Using the first-order interaction energy and the continuum model, we study the long-range interaction between a pair of parallel pristine graphene sheets at zero temperature. The asymptotic form of the obtained potential density, \\varepsilon(D) \\propto -D-3-O(D-4) , is consistent with the random phase approximation and Lifshitz theory. Accordingly, neglectance of the anisotropy, especially the nonzero first-order interaction energy, is the reason why the widely used Lennard-Jones potential approach and dispersion corrections in density functional theory give a wrong asymptotic form \\varepsilon(D) \\propto -D-4 .

  19. Dual-range linearized transimpedance amplifier system

    DOEpatents

    Wessendorf, Kurt O.

    2010-11-02

    A transimpedance amplifier system is disclosed which simultaneously generates a low-gain output signal and a high-gain output signal from an input current signal using a single transimpedance amplifier having two different feedback loops with different amplification factors to generate two different output voltage signals. One of the feedback loops includes a resistor, and the other feedback loop includes another resistor in series with one or more diodes. The transimpedance amplifier system includes a signal linearizer to linearize one or both of the low- and high-gain output signals by scaling and adding the two output voltage signals from the transimpedance amplifier. The signal linearizer can be formed either as an analog device using one or two summing amplifiers, or alternately can be formed as a digital device using two analog-to-digital converters and a digital signal processor (e.g. a microprocessor or a computer).

  20. Hyperspectral range imaging for transportation systems evaluation

    NASA Astrophysics Data System (ADS)

    Bridgelall, Raj; Rafert, J. B.; Atwood, Don; Tolliver, Denver D.

    2016-04-01

    Transportation agencies expend significant resources to inspect critical infrastructure such as roadways, railways, and pipelines. Regular inspections identify important defects and generate data to forecast maintenance needs. However, cost and practical limitations prevent the scaling of current inspection methods beyond relatively small portions of the network. Consequently, existing approaches fail to discover many high-risk defect formations. Remote sensing techniques offer the potential for more rapid and extensive non-destructive evaluations of the multimodal transportation infrastructure. However, optical occlusions and limitations in the spatial resolution of typical airborne and space-borne platforms limit their applicability. This research proposes hyperspectral image classification to isolate transportation infrastructure targets for high-resolution photogrammetric analysis. A plenoptic swarm of unmanned aircraft systems will capture images with centimeter-scale spatial resolution, large swaths, and polarization diversity. The light field solution will incorporate structure-from-motion techniques to reconstruct three-dimensional details of the isolated targets from sequences of two-dimensional images. A comparative analysis of existing low-power wireless communications standards suggests an application dependent tradeoff in selecting the best-suited link to coordinate swarming operations. This study further produced a taxonomy of specific roadway and railway defects, distress symptoms, and other anomalies that the proposed plenoptic swarm sensing system would identify and characterize to estimate risk levels.

  1. Mating system and early viability resistance to habitat fragmentation in a bird-pollinated eucalypt.

    PubMed

    Breed, M F; Ottewell, K M; Gardner, M G; Marklund, M H K; Stead, M G; Harris, J B C; Lowe, A J

    2015-08-01

    Habitat fragmentation has been shown to disrupt ecosystem processes such as plant-pollinator mutualisms. Consequently, mating patterns in remnant tree populations are expected to shift towards increased inbreeding and reduced pollen diversity, with fitness consequences for future generations. However, mating patterns and phenotypic assessments of open-pollinated progeny have rarely been combined in a single study. Here, we collected seeds from 37 Eucalyptus incrassata trees from contrasting stand densities following recent clearance in a single South Australian population (intact woodland=12.6 trees ha(-1); isolated pasture=1.7 trees ha(-1); population area=10 km(2)). 649 progeny from these trees were genotyped at eight microsatellite loci. We estimated genetic diversity, spatial genetic structure, indirect contemporary pollen flow and mating patterns for adults older than the clearance events and open-pollinated progeny sired post-clearance. A proxy of early stage progeny viability was assessed in a common garden experiment. Density had no impact on mating patterns, adult and progeny genetic diversity or progeny growth, but was associated with increased mean pollen dispersal. Weak spatial genetic structure among adults suggests high historical gene flow. We observed preliminary evidence for inbreeding depression related to stress caused by fungal infection, but which was not associated with density. Higher observed heterozygosities in adults compared with progeny may relate to weak selection on progeny and lifetime-accumulated mortality of inbred adults. E. incrassata appears to be resistant to the negative mating pattern and fitness changes expected within fragmented landscapes. This pattern is likely explained by strong outcrossing and regular long-distance pollen flow. PMID:23188172

  2. Mating system and early viability resistance to habitat fragmentation in a bird-pollinated eucalypt

    PubMed Central

    Breed, M F; Ottewell, K M; Gardner, M G; Marklund, M H K; Stead, M G; Harris, J B C; Lowe, A J

    2015-01-01

    Habitat fragmentation has been shown to disrupt ecosystem processes such as plant-pollinator mutualisms. Consequently, mating patterns in remnant tree populations are expected to shift towards increased inbreeding and reduced pollen diversity, with fitness consequences for future generations. However, mating patterns and phenotypic assessments of open-pollinated progeny have rarely been combined in a single study. Here, we collected seeds from 37 Eucalyptus incrassata trees from contrasting stand densities following recent clearance in a single South Australian population (intact woodland=12.6 trees ha−1; isolated pasture=1.7 trees ha−1; population area=10 km2). 649 progeny from these trees were genotyped at eight microsatellite loci. We estimated genetic diversity, spatial genetic structure, indirect contemporary pollen flow and mating patterns for adults older than the clearance events and open-pollinated progeny sired post-clearance. A proxy of early stage progeny viability was assessed in a common garden experiment. Density had no impact on mating patterns, adult and progeny genetic diversity or progeny growth, but was associated with increased mean pollen dispersal. Weak spatial genetic structure among adults suggests high historical gene flow. We observed preliminary evidence for inbreeding depression related to stress caused by fungal infection, but which was not associated with density. Higher observed heterozygosities in adults compared with progeny may relate to weak selection on progeny and lifetime-accumulated mortality of inbred adults. E. incrassata appears to be resistant to the negative mating pattern and fitness changes expected within fragmented landscapes. This pattern is likely explained by strong outcrossing and regular long-distance pollen flow. PMID:23188172

  3. Fiber optic light-scattering measurement system for evaluation of embryo viability: light-scattering characteristics from live mouse embryo

    NASA Astrophysics Data System (ADS)

    Itoh, Harumi; Arai, Tsunenori; Kikuchi, Makoto

    1997-06-01

    We measured angular distribution of the light scattering from live mouse embryo with 632.8nm in wavelength to evaluate the embryo viability. We aim to measure the mitochondrial density in human embryo which have relation to the embryo viability. We have constructed the light scattering measurement system to detect the mitochondrial density non-invasively. We have employed two optical fibers for the illumination and sensing to change the angle between these fibers. There were two dips on the scattering angular distribution from the embryo. These dips existed on 30 and 85 deg. We calculated the scattering angular pattern by Mie theory to fit the measured scattering estimated scattering size and density. The best fitting was obtained when the particle size and density were 0.9 micrometers and 1010 particles per ml, respectively. These values coincided with the approximated values of mitochondrial in the embryo. The measured light scattering may mainly originated from mitochondria in spite of the existence of the various scattering particles in the embryo. Since our simple scattering measurement may offer the mitochondrial density in the embryo, it might become the practical method of human embryo on in vitro fertilization-embryo transfer.

  4. Economic viability of biogas technology

    SciTech Connect

    Agrawal, S.C.; Agrawal, S.; Khare, O.P.

    1983-12-01

    Biogas has emerged as a suitable technology for providing alternative and additional sources of energy, especially for rural areas of developing countries. Although the experience gained in China and India established its technological success, social scientists are still involved in the controversial issue of its economic viability. The available literature presents very contradictory situations, ranging between the two extreme poles of high economic viability and nonviability. Such contradictory conclusions are derived since economic benefits from the technology are influenced by a number of factors. A review of the literature reveals that various factors are either not considered, or that the economics have been worked out assuming a very ideal situation, while biogas plants are operating under very different conditions. Using the coal replacement method even as coal is seldom used by villages is only a single example of this approach. In most of the developing countries, rural populations depend mainly on non-commercial fuels like firewood, dungcakes, agricultural wastes and leaves for cooking and heating purposes. Under the present technological limitations, biogas can most commonly be used for cooking and lighting. For testing the economic viability of biogas systems, a number of authors have considered the benefits in terms of savings in traditional fuels. But considering the actual thermal efficiency of different non-commercial fuel items, as well as biogas, it has still be be decided at what point of the market prices of fuel items that the biogas system becomes economically viable and remains viable. The present paper thus reviews different approaches adopted and suggested for working out the economics or the cost-benefit ratio of the biogas technology at the first stage, and then spells out the factors influencing the economic benefits of the technology under various situations, with the help of empirical

  5. Issues of organizational cybernetics and viability beyond Beer's viable systems model

    NASA Astrophysics Data System (ADS)

    Nechansky, Helmut

    2013-11-01

    The paper starts summarizing the claims of Beer's viable systems model to identify five issues any viable organizations has to deal with in an unequivocal hierarchical structure of five interrelated systems. Then the evidence is introduced for additional issues and related viable structures of organizations, which deviate from Beer's model. These issues are: (1) the establishment and (2) evolution of an organization; (3) systems for independent top-down control (like "Six Sigma"); (4) systems for independent bottom-up correction of performance problems (like "Kaizen"), both working outside a hierarchical structure; (5) pull production systems ("Just in Time") and (6) systems for checks and balances of top-level power (like boards and shareholder meetings). Based on that an evolutionary approach to organizational cybernetics is outlined, addressing the establishment of organizations and possible courses of developments, including recent developments in quality and production engineering, as well as problems of setting and changing goal values determining organizational policies.

  6. Fault tolerant computing: A preamble for assuring viability of large computer systems

    NASA Technical Reports Server (NTRS)

    Lim, R. S.

    1977-01-01

    The need for fault-tolerant computing is addressed from the viewpoints of (1) why it is needed, (2) how to apply it in the current state of technology, and (3) what it means in the context of the Phoenix computer system and other related systems. To this end, the value of concurrent error detection and correction is described. User protection, program retry, and repair are among the factors considered. The technology of algebraic codes to protect memory systems and arithmetic codes to protect memory systems and arithmetic codes to protect arithmetic operations is discussed.

  7. The financial viability of an SOFC cogeneration system in single-family dwellings

    NASA Astrophysics Data System (ADS)

    Alanne, Kari; Saari, Arto; Ugursal, V. Ismet; Good, Joel

    In the near future, fuel cell-based residential micro-CHP systems will compete with traditional methods of energy supply. A micro-CHP system may be considered viable if its incremental capital cost compared to its competitors equals to cumulated savings during a given period of time. A simplified model is developed in this study to estimate the operation of a residential solid oxide fuel cell (SOFC) system. A comparative assessment of the SOFC system vis-à-vis heating systems based on gas, oil and electricity is conducted using the simplified model for a single-family house located in Ottawa and Vancouver. The energy consumption of the house is estimated using the HOT2000 building simulation program. A financial analysis is carried out to evaluate the sensitivity of the maximum allowable capital cost with respect to system sizing, acceptable payback period, energy price and the electricity buyback strategy of an energy utility. Based on the financial analysis, small (1-2 kW e) SOFC systems seem to be feasible in the considered case. The present study shows also that an SOFC system is especially an alternative to heating systems based on oil and electrical furnaces.

  8. Identification, Description, and Perceived Viability of K-12 Consolidated Catholic School Systems

    ERIC Educational Resources Information Center

    Britt, Kenith C.

    2013-01-01

    Catholic education has been in a state of substantial decline since 1965. In order to help sustain the ministry of Catholic schools, one approach that several dozen dioceses have embraced is the K-12 consolidated Catholic school system. This study investigated the organizational structures within consolidated school systems, factors that led to…

  9. The Financial Management System: A Pivotal Tool for Fiscal Viability. CDS Spotlight. ECAR Research Bulletin

    ERIC Educational Resources Information Center

    Lang, Leah; Pirani, Judith A.

    2014-01-01

    This spotlight focuses on data from the 2013 CDS to better understand how higher education institutions approach financial management systems. Information provided for this spotlight was derived from Module 8 of Core Data Service (CDS), which asked several questions regarding information systems and applications. Responses from 525 institutions…

  10. Test techniques for determining laser ranging system performance

    NASA Technical Reports Server (NTRS)

    Zagwodzki, T. W.

    1981-01-01

    Procedures and results of an on going test program intended to evaluate laser ranging system performance levels in the field as well as in the laboratory are summarized. Tests show that laser ranging system design requires consideration of time biases and RMS jitters of individual system components. All simple Q switched lasers tested were found to be inadequate for 10 centimeter ranging systems. Timing discriminators operating over a typical 100:1 dynamic signal range may introduce as much as 7 to 9 centimeters of range bias. Time interval units commercially available today are capable of half centimeter performance and are adequate for all field systems currently deployed. Photomultipliers tested show typical tube time biases of one centimeter with single photoelectron transit time jitter of approximately 10 centimeters. Test results demonstrate that NASA's Mobile Laser Ranging System (MOBLAS) receiver configuration is limiting system performance below the 100 photoelectron level.

  11. Ranging and tracking system for proximity operations, phase 1

    NASA Technical Reports Server (NTRS)

    Udalov, S.; Nilsen, P. W.

    1979-01-01

    A study task is reported which is directed towards developing a conceptual design of a small, lightweight range and range rate radar sensor system to meet NASA's requirements for accurate short-range and velocity measurements in an orbital environment. Within the context of the requirements, the short range implies system operation at 0 m to 1850 m (6000 ft) and accurate implies a range measurement to within 1 sigma accuracy of 0.20 m (0.67 ft) and a range rate (velocity) measurement to within 1 sigma accuracy of 0.01 m/sec (0.033 ft/sec).

  12. Viability of karezes (ancient water supply systems in Afghanistan) in a changing world

    NASA Astrophysics Data System (ADS)

    Macpherson, G. L.; Johnson, W. C.; Liu, Huan

    2015-09-01

    The Afghanistan population living far from rivers relies upon groundwater delivered from karezes (sub-horizontal tunnels). Karezes exploit unconfined groundwater in alluvial fans recharged largely by snowmelt from the Hindu Kush, the central mountain range of the country. Since the multi-year drought that began in 1998, many karezes have stopped flowing. This study characterizes the hydraulics of a kariz, the potential for reduced groundwater recharge because of climate change, and the impact of increasing population on kariz water production. A typical kariz in Afghanistan is 1-2 km long with a cross-section of 1-2 m2 and gradient of 1 m km-1. MODFLOW simulations show that water delivery from a kariz can be modeled by imposing a high ratio of kariz hydraulic conductivity to aquifer hydraulic conductivity on the cells representing the kariz. The model is sensitive to hydraulic conductivity, kariz gradient, and length of the kariz in contact with the water table. Precipitation data are scarce in Afghanistan, but regional data show a long-term trend of decreased snow cover, and therefore strong likelihood of decreased aquifer recharge. Population in Afghanistan has increased at a rate of about 2.2 % over the past several decades. An assessment of a six-district region within Kandahar Province where karezes are the most likely source of water indicates that water demand could have caused water tables to decline by 0.8-5.6 m, more than enough to cause karezes to stop flowing. These results suggest that kariz water production is not sustainable under current climate- and population-growth trends.

  13. Lightning threat warning system at the Tonopah Test Range

    SciTech Connect

    Smith, R

    1992-07-01

    This report documents the lightning threat warning system at the Tonopah Test Range and the technology it uses. The report outlines each of the system's individual components and the information each contributes.

  14. Performance of NASA laser ranging systems during MERIT

    NASA Technical Reports Server (NTRS)

    Coates, Robert J.

    1986-01-01

    The performances of the NASA satellite laser ranging (SLR) systems operating during the 1983-1984 MERIT campaign (SAO 1-2, Moblas 1-8, Hollas, MLRS, TLRS 1-2, and NLRS) are compared. Data for the single shot rms precisions and ranges per pass are given for these systems after most of them were upgraded with Quantel lasers. The Moblas 4-8 and the Hollas systems operated with high signal strength returns; single shot rms precisions of 3.5 to 4 cm and average ranges per pass of 2404 to 2606 points were achieved as compared with the values of 7.5 and 756, respectively, for the TLRS-2 system. In addition to the SLR systems, the NASA lunar laser ranging systems (McDonald 2.7M, MLRS, and NLRS) and their capabilities are discussed together with the history of the lunar laser ranging data quality.

  15. Viability Conditions for a Compartmentalized Protometabolic System: A Semi-Empirical Approach

    PubMed Central

    Piedrafita, Gabriel; Ruiz-Mirazo, Kepa; Monnard, Pierre-Alain; Cornish-Bowden, Athel; Montero, Francisco

    2012-01-01

    In this work we attempt to find out the extent to which realistic prebiotic compartments, such as fatty acid vesicles, would constrain the chemical network dynamics that could have sustained a minimal form of metabolism. We combine experimental and simulation results to establish the conditions under which a reaction network with a catalytically closed organization (more specifically, an ()-system) would overcome the potential problem of self-suffocation that arises from the limited accessibility of nutrients to its internal reaction domain. The relationship between the permeability of the membrane, the lifetime of the key catalysts and their efficiency (reaction rate enhancement) turns out to be critical. In particular, we show how permeability values constrain the characteristic time scale of the bounded protometabolic processes. From this concrete and illustrative example we finally extend the discussion to a wider evolutionary context. PMID:22761803

  16. Integration of motion and stereo sensors in passive ranging systems

    NASA Technical Reports Server (NTRS)

    Sridhar, Banavar; Suorsa, Raymond

    1990-01-01

    A recursive approach is described for processing a sequence of stereo images. It will be the basis for an integrated stereo and motion method to provide more accurate range information using a passive ranging system. Results based on motion sequences of stereo images are presented. The approach is also applicable to other autonomous systems and in robotics.

  17. Assessing the viability of microsponges as gastro retentive drug delivery system of curcumin: optimization and pharmacokinetics.

    PubMed

    Arya, Priyanka; Pathak, Kamla

    2014-01-01

    The work was aimed to validate the gastroretentive potential of microsponges via optimization of targeted floating curcumin microsponges for improved site specific absorption for gastric cancer Modified quasi emulsion solvent diffusion method was used to formulate microsponges using 3(2) full factorial design. The effect of different levels of ethyl cellulose and polyvinyl alcohol concentration, selected as independent variables was determined on the % entrapment efficiency, % buoyancy and % cumulative drug release. Modified rosette rise apparatus was used for in vitro release and the release data best fitted Higuchi's model and mechanism of drug release was diffusion (n). The optimized formulation (MS5) demonstrated favourable % entrapment efficiency (90.7 ± 1.7), % buoyancy (82.0 ± 2.0) and % cumulative drug release (85.2 ± 1.07) with maximum desirability factor of 0.816. SEM revealed spherical and porous microsponges. DSC confirmed molecular dispersion of the drug in the microsponges polymeric matrix. DRIFT revealed no chemical interaction between the drug and polymer used. The in vitro permeation of curcumin through gastric mucin gel layer affirmed the capability of microsponges to deliver drug across mucin r and reach the target site to treat gastric cancer. Anticancer oral dose of microsponges was calculated as 50mg by cytotoxicity assay in human cancer cell line KB. The pharmacokinetic evaluation of MS5 in rabbits revealed 10-fold increase in bioavailability as compared to native curcumin, demonstrated the superiority of microsponges over native curcumin as gastro retentive drug delivery system. This study presents a new approach based on floating ability of microsponges for treatment of gastric cancer. PMID:24184218

  18. Viability Assessment of a Repository at Yucca Mountain. Volume 3: Total System Performance Assessment

    SciTech Connect

    1998-12-01

    This volume reports the development of TSPA for the VA. This first section defines the general process involved in developing any TSPA, it describes the overall TSPA process as implemented by programs in the US and elsewhere in the world, and discusses the acceptability of TSPA as a process or tool for analyzing a nuclear waste repository system. Section 2 discusses the more specific use of the TSPA process for the TSPA-VA for Yucca Mountain, including goals, approach, and methods. It also includes a very brief synopsis of TSPA-VA results. Section 3 briefly discusses each of the component models that comprise the TSPA-VA. Each TSPA component model represents a discrete set of processes. The TSPA-VA components are: unsaturated zone flow, thermal hydrology, near- field geochemical environment, waste package degradation, waste form alteration and mobilization, unsaturated zone transport, saturated zone flow and transport, and biosphere. For each of these components, this section introduces the conceptualization of each individual process, describes the data sources, and discusses model parameter development and computer methods used to simulate each component. Section 4 explains the mechanics of how the individual TSPA components were combined into a ''base case'' and then provides the ''expected value'' results of a deterministic base case analysis. Section 4 also contains a description of the probabilistic analyses and results that help determine the relative importance of the various TSPA components and the data used to describe the components. Section 5 addresses sensitivity studies run for each of the TSPA components to understand how uncertainty in various parameters within a component change the TSPA results. Section 6 presents the findings of the sensitivity studies run on the various components in Section 5, and prioritizes the findings of the entire set of uncertainty and sensitivity studies of the components relative to each other. Section 6 also discusses

  19. Quench dynamics in long-range interacting quantum systems

    NASA Astrophysics Data System (ADS)

    Gong, Zhexuan

    2016-05-01

    A distinctive feature of atomic, molecular, and optical systems is that interactions between particles are often long-ranged. Control techniques from quantum optics often allow one to tune the pattern of these long-range interactions, creating an entirely new degree of freedom, absent in typical condensed matter systems. These tunable long-range interactions can result in very different far-from-equilibrium dynamics compared to systems with only short-range interactions. In the first half of the talk, I will describe how very general types of long-range interactions can qualitatively change the entanglement and correlation growth shortly after a quantum quench. In the second half of the talk I will show that, at longer times, long-range interactions can lead to exotic quasi-stationary states and dynamical phase transitions. These theoretical ideas have been explored in recent trapped-ion experiments, and connections to these experiments will be emphasized in both parts of the talk.

  20. Temperature inversion in long-range interacting systems

    NASA Astrophysics Data System (ADS)

    Teles, Tarcísio N.; Gupta, Shamik; Di Cintio, Pierfrancesco; Casetti, Lapo

    2015-08-01

    Temperature inversions occur in nature, e.g., in the solar corona and in interstellar molecular clouds: Somewhat counterintuitively, denser parts of the system are colder than dilute ones. We propose a simple and appealing way to spontaneously generate temperature inversions in systems with long-range interactions, by preparing them in inhomogeneous thermal equilibrium states and then applying an impulsive perturbation. In similar situations, short-range systems would typically relax to another thermal equilibrium, with a uniform temperature profile. By contrast, in long-range systems, the interplay between wave-particle interaction and spatial inhomogeneity drives the system to nonequilibrium stationary states that generically exhibit temperature inversion. We demonstrate this mechanism in a simple mean-field model and in a two-dimensional self-gravitating system. Our work underlines the crucial role the range of interparticle interaction plays in determining the nature of steady states out of thermal equilibrium.

  1. Integrated laser/radar satellite ranging and tracking system

    NASA Technical Reports Server (NTRS)

    Hoge, F. E.

    1974-01-01

    A laser satellite ranging system that is mounted upon and integrated with a microwave tracking radar is reported. The 1-pulse/sec ruby laser transmitter is attached directly to the radar's elevation axis and radiates through a new opening in the radar's parabolic dish. The laser photomultiplier tube receiver utilizes the radar's existing 20-cm diam f/11 boresight telescope and observes through a similar symmetrically located opening in the dish. The laser system possesses separate ranging system electronics but shares the radar's timing, computer, and data handling/recording systems. The basic concept of the laser/radar is outlined together with a listing of the numerous advantages over present singular laser range-finding systems. The developmental laser hardware is described along with preliminary range-finding results and expectations.

  2. Laser system range calculations and the Lambert W function.

    PubMed

    Steinvall, Ove

    2009-02-01

    The knowledge of range performance versus atmospheric transmission, often given by the visibility, is critical for the design, use, and prediction of laser and passive electro-optic systems. I present a solution of the ladar-lidar equation based on Lambert's W function. This solution will reveal the dependence of the maximum range on the system and target parameters for different atmospheric attenuations and will also allow us to take the signal statistics into account by studying the influence on the threshold signal-to-noise ratio. The method is also applicable to many range calculations for passive systems where the atmospheric loss can be approximated by an exponential term. PMID:19183566

  3. Local dynamic range compensation for scanning electron microscope imaging system.

    PubMed

    Sim, K S; Huang, Y H

    2015-01-01

    This is the extended project by introducing the modified dynamic range histogram modification (MDRHM) and is presented in this paper. This technique is used to enhance the scanning electron microscope (SEM) imaging system. By comparing with the conventional histogram modification compensators, this technique utilizes histogram profiling by extending the dynamic range of each tile of an image to the limit of 0-255 range while retains its histogram shape. The proposed technique yields better image compensation compared to conventional methods. PMID:25969945

  4. Comparison of motion and stereo methods in passive ranging systems

    NASA Technical Reports Server (NTRS)

    Sridhar, Banavar; Suorsa, Raymond

    1991-01-01

    The authors compare the estimates in passive ranging systems using motion and stereo approaches. It is shown that an integrated approach is necessary to provide better range estimates over a field-of-view (FOV) of interest in helicopter flight. The recursive approach for processing a sequence of stereo images, described together with a recursive motion algorithm (RMA), provides the basis for an integrated method to provide more accurate range information. Results based on motion sequences of stereo images are presented.

  5. Detection performance of laser range-gated imaging system

    NASA Astrophysics Data System (ADS)

    Xu, Jun; Li, Xiaofeng; Luo, Jijun; Zhang, Shengxiu; Xu, Yibin

    2010-10-01

    Laser radar is rapidly developing towards very capable sensors for number of applications such as military sensing and guidance, auto collision avoidance, robotic vision and atmospheric sensing. In this paper, the detection performance of non-scanned Laser Rang-gated (LRG) imaging system is studied. In order to compute the detection range of laser active imaging system, the range equation is derived by using laser illuminating model and considering factors which affect system imaging quality. According to the principle of laser radar and the characters of objects and the detectors in special applied setting, it mainly deduced the non-scanned laser radar range equation of the range-gated system, meanwhile, the SNR model of non-scanned LRG imaging system is set up. Then, relationship of the detection probability, the false alarm probability and the signal-to-noise ratio in the non-scanned LRG imaging system are analyzed, the influence factors of system's performance are pointed out, and the solution is proposed. The detection performance simulation software of non-scanned LRG imaging system is designed with MATLAB and the performance of the imaging system is simulated.

  6. Entropy-Based TOA Estimation and SVM-Based Ranging Error Mitigation in UWB Ranging Systems.

    PubMed

    Yin, Zhendong; Cui, Kai; Wu, Zhilu; Yin, Liang

    2015-01-01

    The major challenges for Ultra-wide Band (UWB) indoor ranging systems are the dense multipath and non-line-of-sight (NLOS) problems of the indoor environment. To precisely estimate the time of arrival (TOA) of the first path (FP) in such a poor environment, a novel approach of entropy-based TOA estimation and support vector machine (SVM) regression-based ranging error mitigation is proposed in this paper. The proposed method can estimate the TOA precisely by measuring the randomness of the received signals and mitigate the ranging error without the recognition of the channel conditions. The entropy is used to measure the randomness of the received signals and the FP can be determined by the decision of the sample which is followed by a great entropy decrease. The SVM regression is employed to perform the ranging-error mitigation by the modeling of the regressor between the characteristics of received signals and the ranging error. The presented numerical simulation results show that the proposed approach achieves significant performance improvements in the CM1 to CM4 channels of the IEEE 802.15.4a standard, as compared to conventional approaches. PMID:26007726

  7. Entropy-Based TOA Estimation and SVM-Based Ranging Error Mitigation in UWB Ranging Systems

    PubMed Central

    Yin, Zhendong; Cui, Kai; Wu, Zhilu; Yin, Liang

    2015-01-01

    The major challenges for Ultra-wide Band (UWB) indoor ranging systems are the dense multipath and non-line-of-sight (NLOS) problems of the indoor environment. To precisely estimate the time of arrival (TOA) of the first path (FP) in such a poor environment, a novel approach of entropy-based TOA estimation and support vector machine (SVM) regression-based ranging error mitigation is proposed in this paper. The proposed method can estimate the TOA precisely by measuring the randomness of the received signals and mitigate the ranging error without the recognition of the channel conditions. The entropy is used to measure the randomness of the received signals and the FP can be determined by the decision of the sample which is followed by a great entropy decrease. The SVM regression is employed to perform the ranging-error mitigation by the modeling of the regressor between the characteristics of received signals and the ranging error. The presented numerical simulation results show that the proposed approach achieves significant performance improvements in the CM1 to CM4 channels of the IEEE 802.15.4a standard, as compared to conventional approaches. PMID:26007726

  8. Synbiotic impact of tagatose on viability of Lactobacillus rhamnosus strain GG mediated by the phosphotransferase system (PTS).

    PubMed

    Koh, Ji Hoon; Choi, Seung Hye; Park, Seung Won; Choi, Nag-Jin; Kim, Younghoon; Kim, Sae Hun

    2013-10-01

    Synbiotics, the combination of prebiotics and probiotics, has been shown to produce synergistic effects that promote gastrointestinal well-being of host. Tagatose is a low calorie food ingredient with putative health-promoting benefits. Herein, we investigated its synbiotic impact on the viability of Lactobacillus casei 01 and Lactobacillus rhamnosus strain GG and the potential mechanism involved. Tagatose, as a synbiotic substrate, enhanced the growth of L. casei 01 and L. rhamnosus strain GG compared to other prebiotics. Other gut-indigenous such as Clostridium spp. readily utilized fructooligosaccharide (FOS), the most widely used functional prebiotics, but not tagatose. Additionally, tagatose enhanced probiotic functions of L. casei 01 and L. rhamnosus strain GG by reinforcing their attachment on HT-29 intestine epithelial cells and enhancing their cholesterol-lowering activities. Whole transcriptome study and quantitative real-time polymerase chain reaction (qRT-PCR) test showed that the presence of tagatose in L. rhamnosus strain GG caused induction of a large number of genes associated with carbohydrate metabolism including the phosphotransferase system (PTS). Collectively, these results indicate the tagatose enhanced the growth of L. casei 01 and L. rhamnosus strain GG and their probiotic activities by activating tagatose-associated PTS networks. Importantly, this study highlights the potential application of tagatose and L. casei 01 and/or L. rhamnosus strain GG as a synbiotic partner in functional dairy foods (i.e. yogurt and cheese) and therapeutic dietary supplements. PMID:23764214

  9. Social responsibility, politics, and fiscal viability: strategic issues in the development of a regional health care system for children in South Texas.

    PubMed

    Robertson, K R; Stefl, M E

    1994-01-01

    A case study of the proposed development of a regional children's health care system in South Texas is described. Strategic plans for the system are overviewed and the community response to plans are presented. The political, social responsibility and fiscal viability issues raised are reviewed and the research literature base relevant to the health care needs of a key (Hispanic) market is summarized. PMID:10165477

  10. The airborne laser ranging system, its capabilities and applications

    NASA Technical Reports Server (NTRS)

    Kahn, W. D.; Degnan, J. J.; Englar, T. S., Jr.

    1982-01-01

    The airborne laser ranging system is a multibeam short pulse laser ranging system on board an aircraft. It simultaneously measures the distances between the aircraft and six laser retroreflectors (targets) deployed on the Earth's surface. The system can interrogate over 100 targets distributed over an area of 25,000 sq, kilometers in a matter of hours. Potentially, a total of 1.3 million individual range measurements can be made in a six hour flight. The precision of these range measurements is approximately + or - 1 cm. These measurements are used in procedure which is basically an extension of trilateration techniques to derive the intersite vector between the laser ground targets. By repeating the estimation of the intersite vector, strain and strain rate errors can be estimated. These quantities are essential for crustal dynamic studies which include determination and monitoring of regional strain in the vicinity of active fault zones, land subsidence, and edifice building preceding volcanic eruptions.

  11. Entanglement area law for long-range interacting systems

    NASA Astrophysics Data System (ADS)

    Gong, Zhexuan; Foss-Feig, Michael; Brandao, Fernando G. S. L.; Gorshkov, Alexey V.

    Area laws for entanglement provide crucial insight into the low-energy behavior of many-body systems and are intimately connected to the efficiency of classical computational methods. For 1D systems, an area law was rigorously proven for ground states of gapped Hamiltonians with local interactions and for states with exponentially decaying correlations. In the presence of long-range interactions, the proof of an area law for gapped ground states becomes much more challenging because long-range interactions can change the effective dimensionality of the system and introduce correlations decaying slower than an exponential. Based on recent theoretical advances that reveal strong remnants of locality in quenched systems with power-law decaying interactions, we prove an area law for a large class of gapped Hamiltonians with long-range interactions. As an intermediate step, we prove tight bounds on the decay of ground-state correlations.

  12. On-line range prediction system, part 2

    NASA Technical Reports Server (NTRS)

    Levan, Nhan

    1988-01-01

    The on-line range prediction system is designed for providing a prediction of the target range in the case of a laser data dropout. It consists of real time implementation of a Kalman filter on an IBM PC/AT equipped with necessary hardware. The system was set up and tested at Crows Landing in the Fall of 1987. The improvements made on the on-line range prediction system during 1988 are examined. Solutions are proposed and discussed to the several problems encountered during system tests. Then, the improvements made on the filter software are explained, namely, accounting for the time lag and providing data continously. Finally, the ideas are mentioned that can be considered in the future.

  13. A TRANSPORT SYSTEM FOR THE MAINTENANCE OF VIABILITY OF ACINETOBACTER CALCOACETICUS, STREPTOCOCCUS INIAE, AND S. AGALACTIAE OVER VARYING TIME PERIODS

    Technology Transfer Automated Retrieval System (TEKTRAN)

    We evaluated the utility of Bacti-Swab NPG Modified Stuart's medium (Remel)in maintaining viable Gram negative (Acinetobacter calcoaceticus) and Gram positive bacteria (Streptococcus iniae and S. agalactiae) for up to 10 days. In the first experiment, qualitative assessment of the viability of S. i...

  14. Range accuracy analysis of streak tube imaging lidar systems

    NASA Astrophysics Data System (ADS)

    Ye, Guangchao; Fan, Rongwei; Chen, Zhaodong; Yuan, Wei; Chen, Deying; He, Ping

    2016-02-01

    Streak tube imaging lidar (STIL) is an active imaging system that has a high range accuracy and a wide range gate with the use of a pulsed laser transmitter and streak tube receiver to produce 3D range images. This work investigates the range accuracy performance of STIL systems based on a peak detection algorithm, taking into account the effects of blurring of the image. A theoretical model of the time-resolved signal distribution, including the static blurring width in addition to the laser pulse width, is presented, resulting in a modified range accuracy analysis. The model indicates that the static blurring width has a significant effect on the range accuracy, which is validated by both the simulation and experimental results. By using the optimal static blurring width, the range accuracies are enhanced in both indoor and outdoor experiments, with a stand-off distance of 10 m and 1700 m, respectively, and corresponding, best range errors of 0.06 m and 0.25 m were achieved in a daylight environment.

  15. Range Information Systems Management (RISM) Phase 1 Report

    NASA Technical Reports Server (NTRS)

    Bastin, Gary L.; Harris, William G.; Nelson, Richard A.

    2002-01-01

    RISM investigated alternative approaches, technologies, and communication network architectures to facilitate building the Spaceports and Ranges of the future. RISM started by document most existing US ranges and their capabilities. In parallel, RISM obtained inputs from the following: 1) NASA and NASA-contractor engineers and managers, and; 2) Aerospace leaders from Government, Academia, and Industry, participating through the Space Based Range Distributed System Working Group (SBRDSWG), many of whom are also; 3) Members of the Advanced Range Technology Working Group (ARTWG) subgroups, and; 4) Members of the Advanced Spaceport Technology Working Group (ASTWG). These diverse inputs helped to envision advanced technologies for implementing future Ranges and Range systems that builds on today s cabled and wireless legacy infrastructures while seamlessly integrating both today s emerging and tomorrow s building-block communication techniques. The fundamental key is to envision a transition to a Space Based Range Distributed Subsystem. The enabling concept is to identify the specific needs of Range users that can be solved through applying emerging communication tech

  16. Tonopah Test Range EGS graphics tracking display system: HP370

    SciTech Connect

    Meyer, R.H.; Bauhs, K.C.

    1994-08-01

    This report describes the HP370 component of the Enhanced Graphics System (EGS) used at Tonopah Test Range (TTR). Selected Radar data is fed into the computer systems and the resulting tracking symbols are displayed on high-resolution video monitors in real time. These tracking symbols overlay background maps and are used for monitoring/controlling various flight vehicles. This report discusses both the operational aspects and the internal configuration of the HP370 Workstation portion of the EGS system.

  17. Signal integration enhances the dynamic range in neuronal systems

    NASA Astrophysics Data System (ADS)

    Gollo, Leonardo L.; Mirasso, Claudio; Eguíluz, Víctor M.

    2012-04-01

    The dynamic range measures the capacity of a system to discriminate the intensity of an external stimulus. Such an ability is fundamental for living beings to survive: to leverage resources and to avoid danger. Consequently, the larger is the dynamic range, the greater is the probability of survival. We investigate how the integration of different input signals affects the dynamic range, and in general the collective behavior of a network of excitable units. By means of numerical simulations and a mean-field approach, we explore the nonequilibrium phase transition in the presence of integration. We show that the firing rate in random and scale-free networks undergoes a discontinuous phase transition depending on both the integration time and the density of integrator units. Moreover, in the presence of external stimuli, we find that a system of excitable integrator units operating in a bistable regime largely enhances its dynamic range.

  18. Hybrid gesture recognition system for short-range use

    NASA Astrophysics Data System (ADS)

    Minagawa, Akihiro; Fan, Wei; Katsuyama, Yutaka; Takebe, Hiroaki; Ozawa, Noriaki; Hotta, Yoshinobu; Sun, Jun

    2012-03-01

    In recent years, various gesture recognition systems have been studied for use in television and video games[1]. In such systems, motion areas ranging from 1 to 3 meters deep have been evaluated[2]. However, with the burgeoning popularity of small mobile displays, gesture recognition systems capable of operating at much shorter ranges have become necessary. The problems related to such systems are exacerbated by the fact that the camera's field of view is unknown to the user during operation, which imposes several restrictions on his/her actions. To overcome the restrictions generated from such mobile camera devices, and to create a more flexible gesture recognition interface, we propose a hybrid hand gesture system, in which two types of gesture recognition modules are prepared and with which the most appropriate recognition module is selected by a dedicated switching module. The two recognition modules of this system are shape analysis using a boosting approach (detection-based approach)[3] and motion analysis using image frame differences (motion-based approach)(for example, see[4]). We evaluated this system using sample users and classified the resulting errors into three categories: errors that depend on the recognition module, errors caused by incorrect module identification, and errors resulting from user actions. In this paper, we show the results of our investigations and explain the problems related to short-range gesture recognition systems.

  19. Local cost sharing in Bamako Initiative systems in Benin and Guinea: assuring the financial viability of primary health care.

    PubMed

    Soucat, A; Levy-Bruhl, D; Gbedonou, P; Drame, K; Lamarque, J P; Diallo, S; Osseni, R; Adovohekpe, P; Ortiz, C; Debeugny, C; Knippenberg, R

    1997-06-01

    The fourth in a series of five, this article presents and analyses data on cost recovery and community cost-sharing, two key aspects of the Bamako Initiative which have been implemented in Benin and Guinea since 1986. The data come from approximately 400 health centres and result from the six-monthly monitoring sessions conducted from 1989 to 1993. Community involvement in the financing of local operating costs in the two national scale programmes is also described. In Benin and Guinea, a user fee system generates the community financed revenue with the aim of covering local operating costs including drugs. Health worker salaries remain the responsibility of the government and donor funding covers vaccine and investment costs. Village health committees manage and control resources and revenue. The community is also involved in decision making, strategy definition and quality control. In Benin in 1993, community financing revenue amounted to about US$0.6 per capita per year and generally covered all local recurrent non salary costs except vaccines and left a surplus. Although total costs and revenues were slightly lower in Guinea for the same period, over-all user fee revenue (around US$0.3 per capita per year) covered local recurrent costs (not including salaries or vaccines). A comparison of costs and revenue between regions and individual health centres revealed important differences in cost recovery ratios. In Benin, some centres recovered more than twice the local costs targeted for community financing. Twenty-five per cent of centres in Guinea did not manage to cover their designated local recurrent costs. The longitudinal analysis showed that the level of cost recovery remained stable over time even as preventive care (and especially EPI) coverage rose significantly. To better understand the most important characteristics affecting cost recovery levels, best performing health centres in terms of cost-recovery levels in 1993 were compared to worst performing

  20. Effect of short range hydrodynamic on bimodal colloidal gel systems

    NASA Astrophysics Data System (ADS)

    Boromand, Arman; Jamali, Safa; Maia, Joao

    2015-03-01

    Colloidal Gels and disordered arrested systems has been studied extensively during the past decades. Although, they have found their place in multiple industries such as cosmetic, food and so on, their physical principals are still far beyond being understood. The interplay between different types of interactions from quantum scale, Van der Waals interaction, to short range interactions, depletion interaction, and long range interactions such as electrostatic double layer makes this systems challenging from simulation point of view. Many authors have implemented different simulation techniques such as molecular dynamics (MD) and Brownian dynamics (BD) to capture better picture during phase separation of colloidal system with short range attractive force. However, BD is not capable to include multi-body hydrodynamic interaction and MD is limited by the computational resources and is limited to short time and length scales. In this presentation we used Core-modified dissipative particle dynamics (CM-DPD) with modified depletion potential, as a coarse-grain model, to address the gel formation process in short ranged-attractive colloidal suspensions. Due to the possibility to include and separate short and long ranged-hydrodynamic forces in this method we studied the effect of each of those forces on the final morphology and report one of the controversial question in this field on the effect of hydrodynamics on the cluster formation process on bimodal, soft-hard colloidal mixtures.

  1. Radio Ranging System for Guidance of Approaching Spacecraft

    NASA Technical Reports Server (NTRS)

    Manikonda, Vikram; vanDoom, Eric

    2008-01-01

    A radio communication and ranging system has been proposed for determining the relative position and orientations of two approaching spacecraft to provide guidance for docking maneuvers. On Earth, the system could be used similarly for guiding approaching aircraft and for automated positioning of large, heavy objects. In principle, the basic idea is to (1) measure distances between radio transceivers on the two spacecraft and (2) compute the relative position and orientations from the measured distances.

  2. Covariance analysis of the airborne laser ranging system

    NASA Technical Reports Server (NTRS)

    Englar, T. S., Jr.; Hammond, C. L.; Gibbs, B. P.

    1981-01-01

    The requirements and limitations of employing an airborne laser ranging system for detecting crustal shifts of the Earth within centimeters over a region of approximately 200 by 400 km are presented. The system consists of an aircraft which flies over a grid of ground deployed retroreflectors, making six passes over the grid at two different altitudes. The retroreflector baseline errors are assumed to result from measurement noise, a priori errors on the aircraft and retroreflector positions, tropospheric refraction, and sensor biases.

  3. Compact-range coordinate system established using a laser tracker.

    SciTech Connect

    Gallegos, Floyd H.; Bryce, Edwin Anthony

    2006-12-01

    Establishing a Cartesian coordinate reference system for an existing Compact Antenna Range using the parabolic reflector is presented. A SMX (Spatial Metrix Corporation) M/N 4000 laser-based coordinate measuring system established absolute coordinates for the facility. Electric field characteristics with positional movement correction are evaluated. Feed Horn relocation for alignment with the reflector axis is also described. Reference points are established for follow-on non-laser alignments utilizing a theodolite.

  4. A Cassegrain reflector system for compact range applications

    NASA Technical Reports Server (NTRS)

    Rader, Mark D.; Burnside, Walter D.

    1986-01-01

    An integral part of a compact range is the means of providing a uniform plane wave. A Cassegrain reflector system is one alternative for achieving this goal. Theoretically, this system offers better performance than a simple reflector system. The longer pathlengths in the Cassegrain system lead to a more uniform field in the plane of interest. The addition of the subreflector creates several problems, though. System complexity is increased both in terms of construction and performance analysis. The subreflector also leads to aperture blockage and the orientation of the feed now results in spillover illuminating the target areas as well as the rest of the range. Finally, the addition of the subreflector leads to interaction between the two reflectors resulting in undesired field variations in the plane of interest. These difficulties are addressed and through the concept of blending the surfaces, a Cassegrain reflector system is developed that will provide a uniform plane wave that offers superior performance over large target areas for a given size reflector system. Design and analysis is implemented by considering the main reflector and subreflector separately. Then the system may be put together and the final design and system analysis completed.

  5. Chasing Salmonella Typhimurium in free range egg production system.

    PubMed

    Chousalkar, Kapil; Gole, Vaibhav; Caraguel, Charles; Rault, Jean-Loup

    2016-08-30

    Free range production systems are becoming a major source of egg production in Australia and worldwide. This study investigated shedding and ecology of Salmonella Typhimurium and Salmonella species in a free range layer flock, wild birds and foxes in the vicinity of the free range farm in different seasons. Shedding of Salmonella was significantly higher in summer. Within the shed, overall, Salmonella prevalence was highest in dust. Corticosterone level in faeces was highest in spring and lowest in winter. There was no direct association between the Salmonella shedding (MPN/gm) and corticosterone levels in faeces. Salmonella Typhimurium MLVA types isolated from fox and wild birds were similar to MLVA types isolated from layer flock and reported during human food borne illness. Wild birds and foxes appear to play an important role in S. Typhimurium ecology and food safety. Environmental factors could play a role in evolution of S. Typhimurium in free range environment. PMID:27527766

  6. DEMONSTRATION OF A LONG RANGE TRACER SYSTEM USING PERFLUOROCARBONS

    EPA Science Inventory

    Regional-scale tracer experiments are needed to validate atmospheric dispersion aspects of air pollution models. The capability of a new system, using perfluorocarbon tracers (PFTs), for long-range dispersion experiments at reasonable cost, was demonstrated in two experiments. Tw...

  7. E-prescription as a tool for improving services and the financial viability of healthcare systems: the case of the Greek national e-prescription system.

    PubMed

    Pangalos, G; Sfyroeras, V; Pagkalos, I

    2014-01-01

    E-prescription systems can help improve patient service, safety and quality of care. They can also help achieve better compliance for the patients and better alignment with the guidelines for the practitioners. The recently implemented national e-prescription system in Greece already covers approximately 85% of all prescriptions prescribed in Greece today (approximately 5.5 million per month). The system has not only contributed already in significant changes towards improving services and better monitoring and planning of public health, but also substantially helped to contain unnecessary expenditure related to medication use and improve transparency and administrative control. Such issues have gained increasing importance not only for Greece but also for many other national healthcare systems that have to cope with the continuous rise of medication expenditure. Our implementation has, therefore, shown that besides their importance for improving services, national e-prescription systems can also provide a valuable tool for better utilisation of resources and for containing unnecessary healthcare costs, thus contributing to the improvement of the financial stability and viability of the overall healthcare system. PMID:25161106

  8. Upgrading NASA/DOSE laser ranging system control computers

    NASA Technical Reports Server (NTRS)

    Ricklefs, Randall L.; Cheek, Jack; Seery, Paul J.; Emenheiser, Kenneth S.; Hanrahan, William P., III; Mcgarry, Jan F.

    1993-01-01

    Laser ranging systems now managed by the NASA Dynamics of the Solid Earth (DOSE) and operated by the Bendix Field Engineering Corporation, the University of Hawaii, and the University of Texas have produced a wealth on interdisciplinary scientific data over the last three decades. Despite upgrades to the most of the ranging station subsystems, the control computers remain a mix of 1970's vintage minicomputers. These encompass a wide range of vendors, operating systems, and languages, making hardware and software support increasingly difficult. Current technology allows replacement of controller computers at a relatively low cost while maintaining excellent processing power and a friendly operating environment. The new controller systems are now being designed using IBM-PC-compatible 80486-based microcomputers, a real-time Unix operating system (LynxOS), and X-windows/Motif IB, and serial interfaces have been chosen. This design supports minimizing short and long term costs by relying on proven standards for both hardware and software components. Currently, the project is in the design and prototyping stage with the first systems targeted for production in mid-1993.

  9. A novel track imaging system as a range counter

    NASA Astrophysics Data System (ADS)

    Chen, Z.; Matsufuji, N.; Kanayama, S.; Ishida, A.; Kohno, T.; Koba, Y.; Sekiguchi, M.; Kitagawa, A.; Murakami, T.

    2016-05-01

    An image-intensified, camera-based track imaging system has been developed to measure the tracks of ions in a scintillator block. To study the performance of the detector unit in the system, two types of scintillators, a dosimetrically tissue-equivalent plastic scintillator EJ-240 and a CsI(Tl) scintillator, were separately irradiated with carbon ion (12C) beams of therapeutic energy from HIMAC at NIRS. The images of individual ion tracks in the scintillators were acquired by the newly developed track imaging system. The ranges reconstructed from the images are reported here. The range resolution of the measurements is 1.8 mm for 290 MeV/u carbon ions, which is considered a significant improvement on the energy resolution of the conventional ΔE/E method. The detector is compact and easy to handle, and it can fit inside treatment rooms for in-situ studies, as well as satisfy clinical quality assurance purposes.

  10. The Airborne Laser Ranging System - Its capabilities and applications

    NASA Technical Reports Server (NTRS)

    Kahn, W. D.; Degnan, J. J.; Englar, T. S., Jr.

    1983-01-01

    The Airborne Laser Ranging System is a proposed multibeam short pulse laser ranging system on board an aircraft. It simultaneously measures the distances between the aircraft and six laser retroreflectors (targets) deployed on the earth's surface. Depending on the host aircraft and terrain characteristics, the system can interrogate hundreds of targets distributed over an area as large as 60,000 sq. km in a matter of hours. Potentially, a total of 1.3 million individual range measurements can be made in a 6 hr flight. The precision of these range measurements is approximately 1 cm. These measurements are then used in a procedure which is basically an extension of trilateration techniques to derive the intersite vector between the laser ground targets. By repeating the estimation of the intersite vector, strain and strain rate errors can be estimated. These quantities are essential for crustal dynamic studies which include determination and monitoring of regional strain in the vicinity of active fault zones, land subsidence, and edifice building preceding volcanic eruptions.

  11. Comment on "Temperature inversion in long-range interacting systems".

    PubMed

    Dumin, Yurii V

    2016-06-01

    In the recent paper by Teles et al. [Phys. Rev. E 92, 020101 (2015)]PRESCM1539-375510.1103/PhysRevE.92.020101, it was suggested that the inversed temperature profiles in various astrophysical objects-ranging from the solar corona to the interstellar molecular clouds-can be explained by the specific features of relaxation in the long-range interacting systems. Here, we show that this mechanism can really work in the self-gravitating interstellar gaseous clouds; but it is irrelevant in the solar (and stellar) coronas where stratification of density is produced by the external gravitational field. PMID:27415395

  12. Poster error probability in the Mu-11 Sequential Ranging System

    NASA Technical Reports Server (NTRS)

    Coyle, C. W.

    1981-01-01

    An expression is derived for the posterior error probability in the Mu-2 Sequential Ranging System. An algorithm is developed which closely bounds the exact answer and can be implemented in the machine software. A computer simulation is provided to illustrate the improved level of confidence in a ranging acquisition using this figure of merit as compared to that using only the prior probabilities. In a simulation of 20,000 acquisitions with an experimentally determined threshold setting, the algorithm detected 90% of the actual errors and made false indication of errors on 0.2% of the acquisitions.

  13. Missile tracking and range safety: Tracking Interferometer Pathfinder System (TIPS)

    NASA Astrophysics Data System (ADS)

    Dowgiallo, David J.; Rauen, Stephen; Peters, Wendy M.; Polisensky, Emil J.

    2013-05-01

    The tracking of missiles at close range proximity has been an ongoing challenge for many launch environments. The ability to provide accurate missile trajectory information is imperative for range safety and early termination of flight. In an effort to provide a potential solution to tracking issues that have plagued many traditional techniques, the Tracking Interferometer Pathfinder System (TIPS) was developed at the Naval Research Laboratory, Washington, D.C. The paper herein describes the design, field test, and results of an interferometer deployed for missile tracking.

  14. Comment on "Temperature inversion in long-range interacting systems"

    NASA Astrophysics Data System (ADS)

    Dumin, Yurii V.

    2016-06-01

    In the recent paper by Teles et al. [Phys. Rev. E 92, 020101 (2015)], 10.1103/PhysRevE.92.020101, it was suggested that the inversed temperature profiles in various astrophysical objects—ranging from the solar corona to the interstellar molecular clouds—can be explained by the specific features of relaxation in the long-range interacting systems. Here, we show that this mechanism can really work in the self-gravitating interstellar gaseous clouds; but it is irrelevant in the solar (and stellar) coronas where stratification of density is produced by the external gravitational field.

  15. The Geoscience Laser Altimetry/Ranging System (GLARS)

    NASA Technical Reports Server (NTRS)

    Cohen, S. C.; Degnan, J. J.; Bufton, J. L.; Garvin, J. B.; Abshire, J. B.

    1986-01-01

    The Geoscience Laser Altimetry Ranging System (GLARS) is a highly precise distance measurement system to be used for making extremely accurate geodetic observations from a space platform. It combines the attributes of a pointable laser ranging system making observations to cube corner retroreflectors placed on the ground with those of a nadir looking laser altimeter making height observations to ground, ice sheet, and oceanic surfaces. In the ranging mode, centimeter-level precise baseline and station coordinate determinations will be made on grids consisting of 100 to 200 targets separated by distances from a few tens of kilometers to about 1000 km. These measurements will be used for studies of seismic zone crustal deformations and tectonic plate motions. Ranging measurements will also be made to a coarser, but globally distributed array of retroreflectors for both precise geodetic and orbit determination applications. In the altimetric mode, relative height determinations will be obtained with approximately decimeter vertical precision and 70 to 100 meter horizontal resolution. The height data will be used to study surface topography and roughness, ice sheet and lava flow thickness, and ocean dynamics. Waveform digitization will provide a measure of the vertical extent of topography within each footprint. The planned Earth Observing System is an attractive candidate platform for GLARS since the GLAR data can be used both for direct analyses and for highly precise orbit determination needed in the reduction of data from other sensors on the multi-instrument platform. (1064, 532, and 355 nm)Nd:YAG laser meets the performance specifications for the system.

  16. Ranging Apparatus and Method Implementing Stereo Vision System

    NASA Technical Reports Server (NTRS)

    Li, Larry C. (Inventor); Cox, Brian J. (Inventor)

    1997-01-01

    A laser-directed ranging system for use in telerobotics applications and other applications involving physically handicapped individuals. The ranging system includes a left and right video camera mounted on a camera platform, and a remotely positioned operator. The position of the camera platform is controlled by three servo motors to orient the roll axis, pitch axis and yaw axis of the video cameras, based upon an operator input such as head motion. A laser is provided between the left and right video camera and is directed by the user to point to a target device. The images produced by the left and right video cameras are processed to eliminate all background images except for the spot created by the laser. This processing is performed by creating a digital image of the target prior to illumination by the laser, and then eliminating common pixels from the subsequent digital image which includes the laser spot. The horizontal disparity between the two processed images is calculated for use in a stereometric ranging analysis from which range is determined.

  17. The precision of today's satellite laser ranging systems

    NASA Technical Reports Server (NTRS)

    Dunn, Peter J.; Torrence, Mark H.; Hussen, Van S.; Pearlman, Michael R.

    1993-01-01

    Recent improvements in the accuracy of modern satellite laser ranging (SLR) systems are strengthened by the new capability of many instruments to track an increasing number of geodetic satellite targets without significant scheduling conflict. This will allow the refinement of some geophysical parameters, such as solid Earth tidal effects and GM, and the improved temporal resolution of others, such as Earth orientation and station position. Better time resolution for the locations of fixed observatories will allow us to monitor more subtle motions at the stations, and transportable systems will be able to provide indicators of long term trends with shorter occupations. If we are to take advantage of these improvements, care must be taken to preserve the essential accuracy of an increasing volume of range observations at each stage of the data reduction process.

  18. Sirius: a long-range infrared search and track system

    NASA Astrophysics Data System (ADS)

    Knepper, R.

    1997-08-01

    Sirius is a long range infra red search and track system (LR- IRST) and intended to be used in an anti air warfare (AAW) multisensor suite on board of modern frigates. This Dutch/Canadian development program started 1/1/95 and includes also the evaluation of the system in warm and cold water scenarios. The operational requirements were drafted by both the national navies. The primary task is automatic detection, tracking and reporting of seaskimming missiles at long range. The design is based on recent experiences with IRSTs and the latest technological achievements in the areas of processing capabilities and IR-detectors. In this presentation design drivers and main technical choices are discussed.

  19. Effects of turbulence on the geodynamic laser ranging system

    NASA Technical Reports Server (NTRS)

    Churnside, James H.

    1993-01-01

    The Geodynamic Laser Ranging System (GLRS) is one of several instruments being developed by the National Aeronautics and Space Administration (NASA) for implementation as part of the Earth Observing System in the mid-1990s (Cohen et al., 1987; Bruno et al., 1988). It consists of a laser transmitter and receiver in space and an array of retroreflectors on the ground. The transmitter produces short (100 ps) pulses of light at two harmonics (0.532 and 0.355 microns) of the Nd:YAG laser. These propagate to a retroreflector on the ground and return. The receiver collects the reflected light and measures the round-trip transit time. Ranging from several angles accurately determines the position of the retroreflector, and changes in position caused by geophysical processes can be monitored.

  20. High Dynamic Range Complex Impedance Measurement System for Petrophysical Usage

    NASA Astrophysics Data System (ADS)

    Chen, R.; He, X.; Yao, H.; Tan, S.; Shi, H.; Shen, R.; Yan, C.; Zeng, P.; He, L.; Qiao, N.; Xi, F.; Zhang, H.; Xie, J.

    2015-12-01

    Spectral induced polarization method (SIP) or complex resistivity method is increasing its application in metalliferous ore exploration, hydrocarbon exploration, underground water exploration, monitoring of environment pollution, and the evaluation of environment remediation. And the measurement of complex resistivity or complex impedance of rock/ore sample and polluted water plays a fundamental role in improving the application effect of SIP and the application scope of SIP. However, current instruments can't guaranty the accuracy of measurement when the resistance of sample is less than 10Ω or great than 100kΩ. A lot of samples, such as liquid, polluted sea water, igneous rock, limestone, and sandstone, can't be measured with reliable complex resistivity result. Therefore, this problem projects a shadow in the basic research and application research of SIP. We design a high precision measurement system from the study of measurement principle, sample holder, and measurement instrument. We design input buffers in a single board. We adopt operation amplifier AD549 in this system because of its ultra-high input impedance and ultra-low current noise. This buffer is good in acquiring potential signal across high impedance sample. By analyzing the sources of measurement error and errors generated by the measurement system, we propose a correction method to remove the error in order to achieve high quality complex impedance measurement for rock and ore samples. This measurement system can improve the measurement range of the complex impedance to 0.1 Ω ~ 10 GΩ with amplitude error less than 0.1% and phase error less than 0.1mrad when frequency ranges as 0.01 Hz ~ 1 kHz. We tested our system on resistors with resistance as 0.1Ω ~ 10 GΩ in frequency range as 1 Hz ~ 1000 Hz, and the measurement error is less than 0.1 mrad. We also compared the result with LCR bridge and SCIP, we can find that the bridge's measuring range only reaches 100 MΩ, SCIP's measuring range

  1. Decision Support Systems for Launch and Range Operations Using Jess

    NASA Technical Reports Server (NTRS)

    Thirumalainambi, Rajkumar

    2007-01-01

    The virtual test bed for launch and range operations developed at NASA Ames Research Center consists of various independent expert systems advising on weather effects, toxic gas dispersions and human health risk assessment during space-flight operations. An individual dedicated server supports each expert system and the master system gather information from the dedicated servers to support the launch decision-making process. Since the test bed is based on the web system, reducing network traffic and optimizing the knowledge base is critical to its success of real-time or near real-time operations. Jess, a fast rule engine and powerful scripting environment developed at Sandia National Laboratory has been adopted to build the expert systems providing robustness and scalability. Jess also supports XML representation of knowledge base with forward and backward chaining inference mechanism. Facts added - to working memory during run-time operations facilitates analyses of multiple scenarios. Knowledge base can be distributed with one inference engine performing the inference process. This paper discusses details of the knowledge base and inference engine using Jess for a launch and range virtual test bed.

  2. Peristaltic pump-based low range pressure sensor calibration system

    SciTech Connect

    Vinayakumar, K. B.; Naveen Kumar, G.; Rajanna, K. E-mail: krajanna2011@gmail.com; Nayak, M. M.; Dinesh, N. S.

    2015-11-15

    Peristaltic pumps were normally used to pump liquids in several chemical and biological applications. In the present study, a peristaltic pump was used to pressurize the chamber (positive as well negative pressures) using atmospheric air. In the present paper, we discuss the development and performance study of an automatic pressurization system to calibrate low range (millibar) pressure sensors. The system includes a peristaltic pump, calibrated pressure sensor (master sensor), pressure chamber, and the control electronics. An in-house developed peristaltic pump was used to pressurize the chamber. A closed loop control system has been developed to detect and adjust the pressure leaks in the chamber. The complete system has been integrated into a portable product. The system performance has been studied for a step response and steady state errors. The system is portable, free from oil contaminants, and consumes less power compared to existing pressure calibration systems. The veracity of the system was verified by calibrating an unknown diaphragm based pressure sensor and the results obtained were satisfactory.

  3. Peristaltic pump-based low range pressure sensor calibration system

    NASA Astrophysics Data System (ADS)

    Vinayakumar, K. B.; Naveen Kumar, G.; Nayak, M. M.; Dinesh, N. S.; Rajanna, K.

    2015-11-01

    Peristaltic pumps were normally used to pump liquids in several chemical and biological applications. In the present study, a peristaltic pump was used to pressurize the chamber (positive as well negative pressures) using atmospheric air. In the present paper, we discuss the development and performance study of an automatic pressurization system to calibrate low range (millibar) pressure sensors. The system includes a peristaltic pump, calibrated pressure sensor (master sensor), pressure chamber, and the control electronics. An in-house developed peristaltic pump was used to pressurize the chamber. A closed loop control system has been developed to detect and adjust the pressure leaks in the chamber. The complete system has been integrated into a portable product. The system performance has been studied for a step response and steady state errors. The system is portable, free from oil contaminants, and consumes less power compared to existing pressure calibration systems. The veracity of the system was verified by calibrating an unknown diaphragm based pressure sensor and the results obtained were satisfactory.

  4. Peristaltic pump-based low range pressure sensor calibration system.

    PubMed

    Vinayakumar, K B; Naveen Kumar, G; Nayak, M M; Dinesh, N S; Rajanna, K

    2015-11-01

    Peristaltic pumps were normally used to pump liquids in several chemical and biological applications. In the present study, a peristaltic pump was used to pressurize the chamber (positive as well negative pressures) using atmospheric air. In the present paper, we discuss the development and performance study of an automatic pressurization system to calibrate low range (millibar) pressure sensors. The system includes a peristaltic pump, calibrated pressure sensor (master sensor), pressure chamber, and the control electronics. An in-house developed peristaltic pump was used to pressurize the chamber. A closed loop control system has been developed to detect and adjust the pressure leaks in the chamber. The complete system has been integrated into a portable product. The system performance has been studied for a step response and steady state errors. The system is portable, free from oil contaminants, and consumes less power compared to existing pressure calibration systems. The veracity of the system was verified by calibrating an unknown diaphragm based pressure sensor and the results obtained were satisfactory. PMID:26628178

  5. Prototype air cleaning system for a firing range

    SciTech Connect

    Glissmeyer, J.A.; Mishima, J.; Bamberger, J.A.

    1985-01-01

    This report recommends air cleaning system components for the US Army Ballistics Research Laboratory's new large-caliber firing range, which is used for testing depleted uranium (DU) penetrators. The new air cleaning system has lower operating costs during the life of the system compared to that anticipated for the existing air cleaning system. The existing system consists of three banks of filters in series; the first two banks are prefilters and the last are high-efficiency particulate air (HEPA) filters. The principal disadvantage of the existing filters is that they are not cleanable and reusable. Pacific Northwest Laboratory focused the search for alternate air cleaning equipment on devices that do not employ liquids as part of the particle collection mechanism. Collected dry particles were assumed preferable to a liquid waste stream. The dry particle collection devices identified included electrostatic precipitators; inertial separators using turning vanes or cyclones; and several devices employing a filter medium such as baghouses, cartridge houses, cleanable filters, and noncleanable filters similar to those in the existing system. The economics of practical air cleaning systems employing the dry particle collection devices were evaluated in 294 different combinations. 7 references, 21 figures, 78 tables.

  6. UAV sensor systems for close-range operations

    NASA Astrophysics Data System (ADS)

    Larroque, Clement-Serge; Thompson, Karl S.; Hickman, Duncan

    2002-07-01

    Although UAV systems have received much interest over the last few years, much of this has focused on either relatively large platforms with complex on-board equipment, or micro systems (typically 6' in every dimension). The operational use of low-cost lightweight UAVs as over-the- hill reconnaissance systems is a new concept offering additional flexibility, providing local knowledge and helping maintain operational tempo. An extensive modeling trade-off study has been performed for different sensor technologies and combinations. The model considered configurations including cooled and uncooled IR sensors, visible-band CCD sensors and image intensifiers. These mathematical models provide an evaluation of sensor performance for both navigation and the gathering of reconnaissance imagery, through Resolution Elements calculations (Johnson criteria) and Signal-to-Noise Ratios. Based upon this analysis, a system specification is presented that exploits next generation sensor technologies. Results obtained from a number of UAV trials are reported and used in order to provide model verification and validation of both the operational concepts and the sensor system modeling activities. Considering the sensor system itself, the low-altitude close-range environment ensures high ground resolved distance and signal-to-noise ratios, with low-cost sensors. Coupled with up-to-date image processing software, the imagery provided directly to the section-level units via a simple standard image interface allows a reduction of time response. Finally, future modeling and trials activities are discussed in the framework of the lightweight UAV system roadmap.

  7. Motor Controller System For Large Dynamic Range of Motor Operation

    NASA Technical Reports Server (NTRS)

    Howard, David E. (Inventor); Alhorn, Dean C. (Inventor); Smith, Dennis A. (Inventor); Dutton, Kenneth R. (Inventor); Paulson, Mitchell Scott (Inventor)

    2006-01-01

    A motor controller system uses a rotary sensor with a plurality of signal conditioning units, coupled to the rotary sensor. Each of these units, which is associated with a particular range of motor output shaft rotation rates, generate a feedback signal indicative of the position of the motor s output shaft. A controller (i) converts a selected motor output shaft rotation rate to a corresponding incremental amount of rotational movement for a selected fixed time period, (ii) selects, at periodic completions of the selected fixed time period, the feedback signal from one of the signal conditioning units for which the particular range of motor output shaft rotation rates associated therewith encompasses the selected motor output shaft rotation rate, and (iii) generates a motor drive signal based on a difference between the incremental amount of rotational movement and the feedback signal from the selected one of the signal conditioning Units.

  8. Advanced Range Safety System for High Energy Vehicles

    NASA Technical Reports Server (NTRS)

    Claxton, Jeffrey S.; Linton, Donald F.

    2002-01-01

    The advanced range safety system project is a collaboration between the National Aeronautics and Space Administration and the United States Air Force to develop systems that would reduce costs and schedule for safety approval for new classes of unmanned high-energy vehicles. The mission-planning feature for this system would yield flight profiles that satisfy the mission requirements for the user while providing an increased quality of risk assessment, enhancing public safety. By improving the speed and accuracy of predicting risks to the public, mission planners would be able to expand flight envelopes significantly. Once in place, this system is expected to offer the flexibility of handling real-time risk management for the high-energy capabilities of hypersonic vehicles including autonomous return-from-orbit vehicles and extended flight profiles over land. Users of this system would include mission planners of Space Launch Initiative vehicles, space planes, and other high-energy vehicles. The real-time features of the system could make extended flight of a malfunctioning vehicle possible, in lieu of an immediate terminate decision. With this improved capability, the user would have more time for anomaly resolution and potential recovery of a malfunctioning vehicle.

  9. Geoscience Laser Ranging System design and performance predictions

    NASA Technical Reports Server (NTRS)

    Anderson, Kent L.

    1991-01-01

    The Geoscience Laser System (GLRS) will be a high-precision distance-measuring instrument planned for deployment on the EOS-B platform. Its primary objectives are to perform ranging measurements to ground targets to monitor crustal deformation and tectonic plate motions, and nadir-looking altimetry to determine ice sheet thicknesses, surface topography, and vertical profiles of clouds and aerosols. The system uses a mode-locked, 3-color Nd:YAG laser source, a Microchannel Plate-PMT for absolute time-of-flight (TOF) measurement (at 532 nm), a streak camera for TOF 2-color dispersion measurement (532 nm and 355 nm), and a Si avalanche photodiode for altimeter waveform detection (1064 nm). The performance goals are to make ranging measurements to ground targets with about 1 cm accuracy, and altimetry height measurements over ice with 10 cm accuracy. This paper presents an overview of the design concept developed during a phase B study. System engineering issues and trade studies are discussed, with particular attention to error budgets and performance predictions.

  10. Error analysis for a spaceborne laser ranging system

    NASA Technical Reports Server (NTRS)

    Pavlis, E. C.

    1979-01-01

    The dependence (or independence) of baseline accuracies, obtained from a typical mission of a spaceborne ranging system, on several factors is investigated. The emphasis is placed on a priori station information, but factors such as the elevation cut-off angle, the geometry of the network, the mean orbital height, and to a limited extent geopotential modeling are also examined. The results are obtained through simulations, but some theoretical justification is also given. Guidelines for freeing the results from these dependencies are suggested for most of the factors.

  11. Long-range position and orientation tracking system

    SciTech Connect

    Armstrong, G.A.; Jansen, J.F.; Burks, B.L.

    1995-12-31

    The long-range position and orientation tracking system will consist of two measurement pods, a VME-based computer system, and a detector array. The system is used to measure the position and orientation of a target that may be attached to a robotic arm, teleoperated manipulator, or autonomous vehicle. The pods have been designed to be mounted in the manways of the domes of the Fernald K-65 waste silos. Each pod has two laser scanner subsystems as well as lights and camera systems. One of the laser scanners will be oriented to scan in the pan direction, the other in the tilt direction. As the lasers scan across the detector array, the angles of incidence with each detector are recorded. Combining measurements from each of the four lasers yields sufficient data for a closed-form solution of the transform describing the location and orientation of the content mobilization system (CMS). Redundant detectors will be placed on the CMS to accommodate occlusions, to provide improved measurement accuracy, and to determine the CMS orientation.

  12. Airborne laser ranging system for monitoring regional crustal deformation

    NASA Technical Reports Server (NTRS)

    Degnan, J. J.

    1981-01-01

    Alternate approaches for making the atmospheric correction without benefit of a ground-based meteorological network are discussed. These include (1) a two-color channel that determines the atmospheric correction by measuring the time delay induced by dispersion between pulses at two optical frequencies; (2) single-color range measurements supported by an onboard temperature sounder, pressure altimeter readings, and surface measurements by a few existing meteorological facilities; and (3) inclusion of the quadratic polynomial coefficients as variables to be solved for along with target coordinates in the reduction of the single-color range data. It is anticipated that the initial Airborne Laser Ranging System (ALRS) experiments will be carried out in Southern California in a region bounded by Santa Barbara on the norht and the Mexican border on the south. The target area will be bounded by the Pacific Ocean to the west and will extend eastward for approximately 400 km. The unique ability of the ALRS to provide a geodetic 'snapshot' of such a large area will make it a valuable geophysical tool.

  13. Parallelized Stochastic Cutoff Method for Long-Range Interacting Systems

    NASA Astrophysics Data System (ADS)

    Endo, Eishin; Toga, Yuta; Sasaki, Munetaka

    2015-07-01

    We present a method of parallelizing the stochastic cutoff (SCO) method, which is a Monte-Carlo method for long-range interacting systems. After interactions are eliminated by the SCO method, we subdivide a lattice into noninteracting interpenetrating sublattices. This subdivision enables us to parallelize the Monte-Carlo calculation in the SCO method. Such subdivision is found by numerically solving the vertex coloring of a graph created by the SCO method. We use an algorithm proposed by Kuhn and Wattenhofer to solve the vertex coloring by parallel computation. This method was applied to a two-dimensional magnetic dipolar system on an L × L square lattice to examine its parallelization efficiency. The result showed that, in the case of L = 2304, the speed of computation increased about 102 times by parallel computation with 288 processors.

  14. Detecting Topological Defect Dark Matter Using Coherent Laser Ranging System.

    PubMed

    Yang, Wanpeng; Leng, Jianxiao; Zhang, Shuangyou; Zhao, Jianye

    2016-01-01

    In the last few decades, optical frequency combs with high intensity, broad optical bandwidth, and directly traceable discrete wavelengths have triggered rapid developments in distance metrology. However, optical frequency combs to date have been limited to determine the absolute distance to an object (such as satellite missions). We propose a scheme for the detection of topological defect dark matter using a coherent laser ranging system composed of dual-combs and an optical clock via nongravitational signatures. The dark matter field, which comprises a defect, may interact with standard model particles, including quarks and photons, resulting in the alteration of their masses. Thus, a topological defect may function as a dielectric material with a distinctive frequency-depend index of refraction, which would cause the time delay of a periodic extraterrestrial or terrestrial light. When a topological defect passes through the Earth, the optical path of long-distance vacuum path is altered, this change in optical path can be detected through the coherent laser ranging system. Compared to continuous wavelength(cw) laser interferometry methods, dual-comb interferometry in our scheme excludes systematic misjudgement by measuring the absolute optical path length. PMID:27389642

  15. Range performance impact of noise for thermal system modeling

    NASA Astrophysics Data System (ADS)

    Fanning, Jonathan D.; Teaney, Brian P.; Reynolds, Joseph P.; Du Bosq, Todd W.

    2009-05-01

    This paper presents a comparison of the predictions of NVThermIP to human perception experiment results in the presence of large amounts of noise where the signal to noise ratio is around 1. First, the calculations used in the NVESD imager performance models that deal with sensor noise are described outlining a few errors that appear in the NVThermIP code. A perception experiment is designed to test the range performance predictions of NVThermIP with varying amounts of noise and varying frame rates. NVThermIP is found to overestimate the impact of noise, leading to pessimistic range performance predictions for noisy systems. The perception experiment results are used to find a best fit value of the constant α used to relate system noise to eye noise in the NVESD models. The perception results are also fit to an alternate eye model that handles frame rates below 30Hz and smoothly approaches an accurate prediction of the performance in the presence of static noise. The predictions using the fit data show significantly less error than the predictions from the current model.

  16. Short range spread-spectrum radiolocation system and method

    DOEpatents

    Smith, Stephen F.

    2003-04-29

    A short range radiolocation system and associated methods that allow the location of an item, such as equipment, containers, pallets, vehicles, or personnel, within a defined area. A small, battery powered, self-contained tag is provided to an item to be located. The tag includes a spread-spectrum transmitter that transmits a spread-spectrum code and identification information. A plurality of receivers positioned about the area receive signals from a transmitting tag. The position of the tag, and hence the item, is located by triangulation. The system employs three different ranging techniques for providing coarse, intermediate, and fine spatial position resolution. Coarse positioning information is provided by use of direct-sequence code phase transmitted as a spread-spectrum signal. Intermediate positioning information is provided by the use of a difference signal transmitted with the direct-sequence spread-spectrum code. Fine positioning information is provided by use of carrier phase measurements. An algorithm is employed to combine the three data sets to provide accurate location measurements.

  17. Detecting Topological Defect Dark Matter Using Coherent Laser Ranging System

    NASA Astrophysics Data System (ADS)

    Yang, Wanpeng; Leng, Jianxiao; Zhang, Shuangyou; Zhao, Jianye

    2016-07-01

    In the last few decades, optical frequency combs with high intensity, broad optical bandwidth, and directly traceable discrete wavelengths have triggered rapid developments in distance metrology. However, optical frequency combs to date have been limited to determine the absolute distance to an object (such as satellite missions). We propose a scheme for the detection of topological defect dark matter using a coherent laser ranging system composed of dual-combs and an optical clock via nongravitational signatures. The dark matter field, which comprises a defect, may interact with standard model particles, including quarks and photons, resulting in the alteration of their masses. Thus, a topological defect may function as a dielectric material with a distinctive frequency-depend index of refraction, which would cause the time delay of a periodic extraterrestrial or terrestrial light. When a topological defect passes through the Earth, the optical path of long-distance vacuum path is altered, this change in optical path can be detected through the coherent laser ranging system. Compared to continuous wavelength(cw) laser interferometry methods, dual-comb interferometry in our scheme excludes systematic misjudgement by measuring the absolute optical path length.

  18. Detecting Topological Defect Dark Matter Using Coherent Laser Ranging System

    PubMed Central

    Yang, Wanpeng; Leng, Jianxiao; Zhang, Shuangyou; Zhao, Jianye

    2016-01-01

    In the last few decades, optical frequency combs with high intensity, broad optical bandwidth, and directly traceable discrete wavelengths have triggered rapid developments in distance metrology. However, optical frequency combs to date have been limited to determine the absolute distance to an object (such as satellite missions). We propose a scheme for the detection of topological defect dark matter using a coherent laser ranging system composed of dual-combs and an optical clock via nongravitational signatures. The dark matter field, which comprises a defect, may interact with standard model particles, including quarks and photons, resulting in the alteration of their masses. Thus, a topological defect may function as a dielectric material with a distinctive frequency-depend index of refraction, which would cause the time delay of a periodic extraterrestrial or terrestrial light. When a topological defect passes through the Earth, the optical path of long-distance vacuum path is altered, this change in optical path can be detected through the coherent laser ranging system. Compared to continuous wavelength(cw) laser interferometry methods, dual-comb interferometry in our scheme excludes systematic misjudgement by measuring the absolute optical path length. PMID:27389642

  19. Application of Digital Polarity Correlators in a Sonar Ranging System

    NASA Astrophysics Data System (ADS)

    Kodama, Tetsuji; Nakahira, Kenji; Kanaya, Yuuki; Yoshikawa, Takahiko

    In robotics applications, ultrasonic transducers are frequently used as rangefinders, thanks to their low cost and small size. The pulse compression techniques were adopted to locate multiple objects at the same time and to eliminate frequent misreadings caused by crosstalk or external ultrasound sources. However, a few problems become apparent when implementing the pulse compression techniques. First, each transducer must be equipped with a processing system for the implementation of correlation functions. This may significantly increase the complexity of the total system, cutting down one of the advantages of ultrasonic systems. Second, the majority of transducers for use in air are based on piezoelectric design, which usually used over a narrow bandwidth. Among digital correlators, significant reductions of the processing cost can be achieved with a polarity correlator. However, this polarity correlation adds quantisation noise to the signals and leads to a degradation of the output signal to noise ratio. This paper presents an analysis of the polarity correlator applying to a sonar ranging system, consisting of piezoelectric transducers and a chirp filter. A numerical evaluation of the output signal shows that the signal to noise ratio degrades only a small amount comparable with that obtained by direct digital correlators.

  20. An ultrasonic ranging system for structural vibration measurements

    NASA Astrophysics Data System (ADS)

    Figueroa, Fernando; Barbieri, Enrique

    1991-08-01

    An ultrasonic ranging system (URS) that can be used to measure vibratory displacements in structures is described. A pair of ultrasonic transducers is used in a transmit-receive mode to acquire the motion of a point on a flexible structure. The structure's oscillating motion modulates the phase angle between the transmitted and received acoustic signals. A simple phase detector and low-pass filter combination demodulate the phase signal, thus extracting information about the motion of the point on the structure. The results reported concentrate on some design issues of the URS and its use as a potential displacement measuring device for flexible structures. The URS accurately distinguished four vibration frequencies of a simple cantilevered aluminum beam, with the highest frequency near 50 Hz.

  1. Linear optical coherence tomography system with extended measurement range.

    PubMed

    Koch, Peter; Hellemanns, Volker; Hüttmann, Gereon

    2006-10-01

    Optical coherence tomography (OCT) sensors traditionally use scanning optical delay lines with moving parts and a single detector. OCT systems with a linear detector array (linear OCT or L-OCT) are simple and robust, but a detector with approximately 10,000 pixels is needed for an imaging depth of 2mm, which is necessary for most biomedical applications. We present a new optical setup for L-OCT with an increased measurement range. An additional grating performs a reduction of the spatial frequencies of the fringe pattern on the detector without loss in the signal-to-noise ratio, so the signal can be sampled with a minimal number of pixels. The theory for this approach is addressed and the first measurements are presented. PMID:16969410

  2. A magnetic suspension system with a large angular range

    NASA Technical Reports Server (NTRS)

    Britcher, Colin P.; Ghofrani, Mehran

    1993-01-01

    The paper describes a small-scale laboratory system, called the Large-Angle Magnetic Suspension Test Fixture (LAMSTF), constructed at NASA Langley Research Center in order to explore and develop technology required for the magnetic suspension of objects over large ranges of orientation. The LAMSTF hardware comprises five electromagnets in a circular arrangement, each driven from a separate bipolar power amplifier. The suspended element is a cylindrical axially magnetized permanent magnet core, within an aluminum tube. The element, which is 'levitated' by repulsive forces, is stabilized in five degrees-of-freedom, with rotation about the cylinder axis not controlled. The controller accommodates the changes in magnetic coupling between the electromagnets and the suspended element by real-time adaptation of a decoupling matrix. The paper presents performance measurements demonstrating that the major design objective of the 360 deg rotation was accomplished.

  3. Nd:YAG development for spaceborne laser ranging system

    NASA Technical Reports Server (NTRS)

    Harper, L. L.; Logan, K. E.; Williams, R. H.; Stevens, D. A.

    1979-01-01

    The results of the development of a unique modelocked laser device to be utilized in future NASA space-based, ultraprecision laser ranger systems are summarized. The engineering breadboard constructed proved the feasibility of the pump-pulsed, actively modelocked, PTM Q-switched Nd:YAG laser concept for the generation of subnanosecond pulses suitable for ultra-precision ranging. The laser breadboard also included a double-pass Nd:YAG amplifier and provision for a Type II KD*P frequency doubler. The specific technical accomplishment was the generation of single 150 psec, 20-mJ pulses at 10 pps at a wavelength of 1.064 micrometers with 25 dB suppression of pre-and post-pulses.

  4. Wide tracking range, auto ranging, low jitter phase lock loop for swept and fixed frequency systems

    DOEpatents

    Kerner, Thomas M.

    2001-01-01

    The present invention provides a wide tracking range phase locked loop (PLL) circuit that achieves minimal jitter in a recovered clock signal, regardless of the source of the jitter (i.e. whether it is in the source or the transmission media). The present invention PLL has automatic harmonic lockout detection circuitry via a novel lock and seek control logic in electrical communication with a programmable frequency discriminator and a code balance detector. (The frequency discriminator enables preset of a frequency window of upper and lower frequency limits to derive a programmable range within which signal acquisition is effected. The discriminator works in combination with the code balance detector circuit to minimize the sensitivity of the PLL circuit to random data in the data stream). In addition, the combination of a differential loop integrator with the lock and seek control logic obviates a code preamble and guarantees signal acquisition without harmonic lockup. An adaptive cable equalizer is desirably used in combination with the present invention PLL to recover encoded transmissions containing a clock and/or data. The equalizer automatically adapts to equalize short haul cable lengths of coaxial and twisted pair cables or wires and provides superior jitter performance itself. The combination of the equalizer with the present invention PLL is desirable in that such combination permits the use of short haul wires without significant jitter.

  5. Performance of the upgraded Orroral laser ranging system

    NASA Technical Reports Server (NTRS)

    Luck, John M.

    1993-01-01

    The topics discussed include the following: upgrade arrangements, system prior to 1991, elements of the upgrade, laser performance, timing system performance, pass productivity, system precision, system accuracy, telescope pointing and future upgrades and extensions.

  6. Challenge testing the lactoperoxidase system against a range of bacteria using different activation agents.

    PubMed

    Fweja, L W T; Lewis, M J; Grandison, A S

    2008-07-01

    Lactoperoxidase (LP) exerts antimicrobial effects in combination with H(2)O(2) and either thiocyanate (SCN(-)) or a halide (e.g., I(-)). Garlic extract in the presence of ethanol has also been used to activate the LP system. This study aimed to determine the effects of 3 LP activation systems (LP+SCN(-)+H(2)O(2); LP+I(-)+H(2)O(2); LP + garlic extract + ethanol) on the growth and activity of 3 test organisms (Staphylococcus aureus, Pseudomonas aeruginosa, and Bacillus cereus). Sterilized milk was used as the reaction medium, and the growth pattern of the organisms and a range of keeping quality (KQ) indicators (pH, titratable acidity, ethanol stability, clot on boiling) were monitored during storage at the respective optimum growth temperature for each organism. The LP+I(-)+ H(2)O(2) system reduced bacterial counts below the detection limit shortly after treatment for all 3 organisms, and no bacteria could be detected for the duration of the experiment (35 to 55 h). The KQ data confirmed that the milk remained unspoiled at the end of the experiments. The LP + garlic extract + ethanol system, on the other hand, had no effect on the growth or KQ with P. aeruginosa, but showed a small retardation of growth of the other 2 organisms, accompanied by small increases (5 to 10 h) in KQ. The effects of the LP+SCN(-)+H(2)O(2) system were intermediate between those of the other 2 systems and differed between organisms. With P. aeruginosa, the system exerted total inhibition within 10 h of incubation, but the bacteria regained viability after a further 5 h, following a logarithmic growth curve. This was reflected in the KQ indicators, which implied an extension of 15 h. With the other 2 bacterial species, LP+SCN(-)+H(2)O(2) exerted an obvious inhibitory effect, giving a lag phase in the growth curve of 5 to 10 h and KQ extension of 10 to 15 h. When used in combination, I(-) and SCN(-) displayed negative synergy. PMID:18565914

  7. Spectroscopic imaging system for high-throughput viability assessment of ovarian spheroids or microdissected tumor tissues (MDTs) in a microfluidic chip

    NASA Astrophysics Data System (ADS)

    St-Georges-Robillard, A.; Masse, M.; Kendall-Dupont, J.; Strupler, M.; Patra, B.; Jermyn, M.; Mes-Masson, A.-M.; Leblond, F.; Gervais, T.

    2016-02-01

    There is a growing effort in the biomicrosystems community to develop a personalized treatment response assay for cancer patients using primary cells, patient-derived spheroids, or live tissues on-chip. Recently, our group has developed a technique to cut tumors in 350 μm diameter microtissues and keep them alive on-chip, enabling multiplexed in vitro drug assays on primary tumor tissue. Two-photon microscopy, confocal microscopy and flow cytometry are the current standard to assay tissue chemosensitivity on-chip. While these techniques provide microscopic and molecular information, they are not adapted for high-throughput analysis of microtissues. We present a spectroscopic imaging system that allows rapid quantitative measurements of multiple fluorescent viability markers simultaneously by using a liquid crystal tunable filter to record fluorescence and transmittance spectra. As a proof of concept, 24 spheroids composed of ovarian cancer cell line OV90 were formed in a microfluidic chip, stained with two live cell markers (CellTrackerTM Green and Orange), and imaged. Fluorescence images acquired were normalized to the acquisition time and gain of the camera, dark noise was removed, spectral calibration was applied, and spatial uniformity was corrected. Spectral un-mixing was applied to separate each fluorophore's contribution. We have demonstrated that rapid and simultaneous viability measurements on multiple spheroids can be achieved, which will have a significant impact on the prediction of a tumor's response to multiple treatment options. This technique may be applied as well in drug discovery to assess the potential of a drug candidate directly on human primary tissue.

  8. Parallel Processing Systems for Passive Ranging During Helicopter Flight

    NASA Technical Reports Server (NTRS)

    Sridhar, Bavavar; Suorsa, Raymond E.; Showman, Robert D. (Technical Monitor)

    1994-01-01

    The complexity of rotorcraft missions involving operations close to the ground result in high pilot workload. In order to allow a pilot time to perform mission-oriented tasks, sensor-aiding and automation of some of the guidance and control functions are highly desirable. Images from an electro-optical sensor provide a covert way of detecting objects in the flight path of a low-flying helicopter. Passive ranging consists of processing a sequence of images using techniques based on optical low computation and recursive estimation. The passive ranging algorithm has to extract obstacle information from imagery at rates varying from five to thirty or more frames per second depending on the helicopter speed. We have implemented and tested the passive ranging algorithm off-line using helicopter-collected images. However, the real-time data and computation requirements of the algorithm are beyond the capability of any off-the-shelf microprocessor or digital signal processor. This paper describes the computational requirements of the algorithm and uses parallel processing technology to meet these requirements. Various issues in the selection of a parallel processing architecture are discussed and four different computer architectures are evaluated regarding their suitability to process the algorithm in real-time. Based on this evaluation, we conclude that real-time passive ranging is a realistic goal and can be achieved with a short time.

  9. Microcanonical Analysis on a System with Long-Range Interactions

    NASA Astrophysics Data System (ADS)

    Hou, Ji-Xuan; Yu, Xu-Chen; Hou, Jing-Min

    2016-09-01

    We study a long-range interacting spin chain placed in a staggered magnetic field using microcanonical approach and obtain the global phase diagram. We find that this model exhibits both first order phase transition and second order phase transition separated by a tricritical point, and temperature jump can be observed in the first order phase transition.

  10. Observability in strategic models of viability selection.

    PubMed

    Gámez, M; Carreño, R; Kósa, A; Varga, Z

    2003-10-01

    Strategic models of frequency-dependent viability selection, in terms of mathematical systems theory, are considered as a dynamic observation system. Using a general sufficient condition for observability of nonlinear systems with invariant manifold, it is studied whether, observing certain phenotypic characteristics of the population, the development of its genetic state can be recovered, at least near equilibrium. PMID:14563566

  11. Protein-protein interactions within the Fatty Acid Synthase-II system of Mycobacterium tuberculosis are essential for mycobacterial viability.

    PubMed

    Veyron-Churlet, Romain; Guerrini, Olivier; Mourey, Lionel; Daffé, Mamadou; Zerbib, Didier

    2004-12-01

    Despite the existence of efficient chemotherapy, tuberculosis remains a leading cause of mortality worldwide. New drugs are urgently needed to reduce the potential impact of the emergence of multidrug-resistant strains of the causative agent Mycobacterium tuberculosis (Mtb). The front-line antibiotic isoniazid (INH), and several other drugs, target the biosynthesis of mycolic acids and especially the Fatty Acid Synthase-II (FAS-II) elongation system. This biosynthetic pathway is essential and specific for mycobacteria and still represents a valuable system for the search of new anti-tuberculous agents. Several data, in the literature, suggest the existence of protein-protein interactions within the FAS-II system. These interactions themselves might serve as targets for a new generation of drugs directed against Mtb. By using an extensive in vivo yeast two-hybrid approach and in vitro co-immunoprecipitation, we have demonstrated the existence of both homotypic and heterotypic interactions between the known components of FAS-II. The condensing enzymes KasA, KasB and mtFabH interact with each other and with the reductases MabA and InhA. Furthermore, we have designed and constructed point mutations of the FAS-II reductase MabA, able to disrupt its homotypic interactions and perturb the interaction pattern of this protein within FAS-II. Finally, we showed by a transdominant genetic approach that these mutants are dominant negative in both non-pathogenic and pathogenic mycobacteria. These data allowed us to draw a dynamic model of the organization of FAS-II. They also represent an important step towards the design of a new generation of anti-tuberculous agents, as being inhibitors of essential protein-protein interactions. PMID:15554959

  12. Distributed Collector Systems (DCS) for the medium temperature range

    NASA Astrophysics Data System (ADS)

    Kalt, A. C.

    1982-11-01

    The basic layout of a distributed collector system (DCS) is described and questions concerning design are discussed. Plant designs and performance data for four DCS systems are presented. Energy storage techniques, the power conversion cycle, and heat transfer subsystems are addressed.

  13. Fusion of a Variable Baseline System and a Range Finder

    PubMed Central

    Hernández-Aceituno, Javier; Acosta, Leopoldo; Arnay, Rafael

    2012-01-01

    One of the greatest difficulties in stereo vision is the appearance of ambiguities when matching similar points from different images. In this article we analyze the effectiveness of using a fusion of multiple baselines and a range finder from a theoretical point of view, focusing on the results of using both prismatic and rotational articulations for baseline generation, and offer a practical case to prove its efficiency on an autonomous vehicle. PMID:22368469

  14. Fusion of a variable baseline system and a range finder.

    PubMed

    Hernández-Aceituno, Javier; Acosta, Leopoldo; Arnay, Rafael

    2012-01-01

    One of the greatest difficulties in stereo vision is the appearance of ambiguities when matching similar points from different images. In this article we analyze the effectiveness of using a fusion of multiple baselines and a range finder from a theoretical point of view, focusing on the results of using both prismatic and rotational articulations for baseline generation, and offer a practical case to prove its efficiency on an autonomous vehicle. PMID:22368469

  15. A proposed test area for the spaceborne geodynamic ranging system

    NASA Technical Reports Server (NTRS)

    Lowman, P. D., Jr.

    1978-01-01

    Precise geodetic measurements are proposed in which an orbiting laser obtains intersite distance between retroreflectors 25 to 100 km apart on the ground. The recommended area is a rectangle 200 by 400 km in southern California and adjacent Nevada, trending northeast. It includes the entire width of the San Andreas fault zone, the Garlock fault, the thrust faults of the Transverse Ranges, and the active strike-slip faults of the Mojave Desert.

  16. Range Safety for an Autonomous Flight Safety System

    NASA Technical Reports Server (NTRS)

    Lanzi, Raymond J.; Simpson, James C.

    2010-01-01

    The Range Safety Algorithm software encapsulates the various constructs and algorithms required to accomplish Time Space Position Information (TSPI) data management from multiple tracking sources, autonomous mission mode detection and management, and flight-termination mission rule evaluation. The software evaluates various user-configurable rule sets that govern the qualification of TSPI data sources, provides a prelaunch autonomous hold-launch function, performs the flight-monitoring-and-termination functions, and performs end-of-mission safing

  17. Noise pair velocity and range echo location system

    SciTech Connect

    Erskine, David J.

    1999-01-01

    An echo-location method for microwaves, sound and light capable of using incoherent and arbitrary waveforms of wide bandwidth to measure velocity and range (and target size) simultaneously to high resolution. Two interferometers having very long and nearly equal delays are used in series with the target interposed. The delays can be longer than the target range of interest. The first interferometer imprints a partial coherence on an initially incoherent source which allows autocorrelation to be performed on the reflected signal to determine velocity. A coherent cross-correlation subsequent to the second interferometer with the source determines a velocity discriminated range. Dithering the second interferometer identifies portions of the cross-correlation belonging to a target apart from clutter moving at a different velocity. The velocity discrimination is insensitive to all slowly varying distortions in the signal path. Speckle in the image of target and antenna lobing due to parasitic reflections is minimal for an incoherent source. An arbitrary source which varies its spectrum dramatically and randomly from pulse to pulse creates a radar elusive to jamming. Monochromatic sources which jigger in frequency from pulse to pulse or combinations of monochromatic sources can simulate some benefits of incoherent broadband sources. Clutter which has a symmetrical velocity spectrum will self-cancel for short wavelengths, such as the apparent motion of ground surrounding target from a sidelooking airborne antenna.

  18. Noise pair velocity and range echo location system

    DOEpatents

    Erskine, D.J.

    1999-02-16

    An echo-location method for microwaves, sound and light capable of using incoherent and arbitrary waveforms of wide bandwidth to measure velocity and range (and target size) simultaneously to high resolution is disclosed. Two interferometers having very long and nearly equal delays are used in series with the target interposed. The delays can be longer than the target range of interest. The first interferometer imprints a partial coherence on an initially incoherent source which allows autocorrelation to be performed on the reflected signal to determine velocity. A coherent cross-correlation subsequent to the second interferometer with the source determines a velocity discriminated range. Dithering the second interferometer identifies portions of the cross-correlation belonging to a target apart from clutter moving at a different velocity. The velocity discrimination is insensitive to all slowly varying distortions in the signal path. Speckle in the image of target and antenna lobing due to parasitic reflections is minimal for an incoherent source. An arbitrary source which varies its spectrum dramatically and randomly from pulse to pulse creates a radar elusive to jamming. Monochromatic sources which jigger in frequency from pulse to pulse or combinations of monochromatic sources can simulate some benefits of incoherent broadband sources. Clutter which has a symmetrical velocity spectrum will self-cancel for short wavelengths, such as the apparent motion of ground surrounding target from a sidelooking airborne antenna. 46 figs.

  19. Wurtzite Zn1-y(MgxCd1-x)yO quaternary systems for photodiodes in visible spectral range

    NASA Astrophysics Data System (ADS)

    Nieda, Yoshiaki; Suzuki, Mari; Nakamura, Atsushi; Temmyo, Jiro; Tabares, Gema; Kurtz, Alejandro; Lopez, Manuel; Ulloa, José María; Hierro, Adrian; Muñoz, Elías

    2016-09-01

    We investigated the optical bandgap engineering of ZnO based quaternary alloy films of wurtzite Zn1-y(MgxCd1-x)yO for photodiodes in visible spectral range. Quaternary alloy films were successfully synthesized by remote-plasma enhanced metalorganic chemical vapor deposition (RPE-MOCVD). The wurtzite alloy system has an optical bandgap energy between 2.16 eV and 3.25 eV, which was controlled by the flow ratio of metalorganic sources. The crystal structure and composition was analyzed by X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). This revealed that carrier compensation effects by alloying with MgO in Zn1-xCdxO system decreases carrier concentration. Strong compensation effects were observed in the bandgap range of Zn1-y(MgxCd1-x)yO between 3.0 eV to 3.25 eV and the carrier concentration decreased to 1015-1018 cm-3. Schottky diodes of PEDOT: PSS/Zn1-y(MgxCd1-y)yO with optical bandgaps in the visible spectral range were fabricated to confirm the viability of photovoltaic applications. The diodes performed photovoltaic characteristics under a Xe-Hg lamp illumination through Schottky junctions. The photoresponse spectra showed a photosensitivity with cutoff energy of 2.23 eV and peak energy of 2.90 eV at 0 V biasing.

  20. Advanced aerial film processing system for long range reconnaissance

    NASA Astrophysics Data System (ADS)

    Ryman, I. G.

    1980-01-01

    An introduction is given to the system features and development histories of continuous aerial film processing equipment. The advantages and disadvantages of (1) deep tank, full immersion processing, (2) spray processing, and (3) viscous processing are enumerated, with respect to load end, supply accumulator, spray cabinet, squeegee section, dryer, film take-up section and film transport system functions. Future research efforts are recommended toward the incorporation of water regeneration, pollution control, and pH monitoring and control systems, and the greater use of computer technology to prevent operator errors and permit the handling of thinner, advanced films.

  1. Morphological observation and analysis using automated image cytometry for the comparison of trypan blue and fluorescence-based viability detection method.

    PubMed

    Chan, Leo Li-Ying; Kuksin, Dmitry; Laverty, Daniel J; Saldi, Stephanie; Qiu, Jean

    2015-05-01

    The ability to accurately determine cell viability is essential to performing a well-controlled biological experiment. Typical experiments range from standard cell culturing to advanced cell-based assays that may require cell viability measurement for downstream experiments. The traditional cell viability measurement method has been the trypan blue (TB) exclusion assay. However, since the introduction of fluorescence-based dyes for cell viability measurement using flow or image-based cytometry systems, there have been numerous publications comparing the two detection methods. Although previous studies have shown discrepancies between TB exclusion and fluorescence-based viability measurements, image-based morphological analysis was not performed in order to examine the viability discrepancies. In this work, we compared TB exclusion and fluorescence-based viability detection methods using image cytometry to observe morphological changes due to the effect of TB on dead cells. Imaging results showed that as the viability of a naturally-dying Jurkat cell sample decreased below 70 %, many TB-stained cells began to exhibit non-uniform morphological characteristics. Dead cells with these characteristics may be difficult to count under light microscopy, thus generating an artificially higher viability measurement compared to fluorescence-based method. These morphological observations can potentially explain the differences in viability measurement between the two methods. PMID:24643390

  2. Web-GIS oriented systems viability for municipal solid waste selective collection optimization in developed and transient economies.

    PubMed

    Rada, E C; Ragazzi, M; Fedrizzi, P

    2013-04-01

    Municipal solid waste management is a multidisciplinary activity that includes generation, source separation, storage, collection, transfer and transport, processing and recovery, and, last but not least, disposal. The optimization of waste collection, through source separation, is compulsory where a landfill based management must be overcome. In this paper, a few aspects related to the implementation of a Web-GIS based system are analyzed. This approach is critically analyzed referring to the experience of two Italian case studies and two additional extra-European case studies. The first case is one of the best examples of selective collection optimization in Italy. The obtained efficiency is very high: 80% of waste is source separated for recycling purposes. In the second reference case, the local administration is going to be faced with the optimization of waste collection through Web-GIS oriented technologies for the first time. The starting scenario is far from an optimized management of municipal solid waste. The last two case studies concern pilot experiences in China and Malaysia. Each step of the Web-GIS oriented strategy is comparatively discussed referring to typical scenarios of developed and transient economies. The main result is that transient economies are ready to move toward Web oriented tools for MSW management, but this opportunity is not yet well exploited in the sector. PMID:23402896

  3. Heart rate, multiple body temperature, long-range and long-life telemetry system for free-ranging animals

    NASA Technical Reports Server (NTRS)

    Lund, G. F.; Westbrook, R. M.; Fryer, T. B.

    1980-01-01

    The design details and rationale for a versatile, long-range, long-life telemetry data acquisition system for heart rates and body temperatures at multiple locations from free-ranging animals are presented. The design comprises an implantable transmitter for short to medium range transmission, a receiver retransmitter collar to be worn for long-range transmission, and a signal conditioner interface circuit to assist in signal discrimination and demodulation of receiver or tape-recorded audio outputs. Implanted electrodes are used to obtain an ECG, from which R-wave characteristics are selected to trigger a short RF pulse. Pulses carrying heart rate information are interrupted periodically by a series of pulse interval modulated RF pulses conveying temperature information sensed at desired locations by thermistors. Pulse duration and pulse sequencing are used to discriminate between heart rate and temperature pulses as well as radio frequency interference. The implanted transmitter may be used alone for medium and short-range tracking, or with a receiver-transmitter collar that employs commercial tracking equipment for transmissions of up to 12 km. A system prototype has been tested on a dog.

  4. Web-GIS oriented systems viability for municipal solid waste selective collection optimization in developed and transient economies

    SciTech Connect

    Rada, E.C.; Ragazzi, M.; Fedrizzi, P.

    2013-04-15

    Highlights: ► As an appropriate solution for MSW management in developed and transient countries. ► As an option to increase the efficiency of MSW selective collection. ► As an opportunity to integrate MSW management needs and services inventories. ► As a tool to develop Urban Mining actions. - Abstract: Municipal solid waste management is a multidisciplinary activity that includes generation, source separation, storage, collection, transfer and transport, processing and recovery, and, last but not least, disposal. The optimization of waste collection, through source separation, is compulsory where a landfill based management must be overcome. In this paper, a few aspects related to the implementation of a Web-GIS based system are analyzed. This approach is critically analyzed referring to the experience of two Italian case studies and two additional extra-European case studies. The first case is one of the best examples of selective collection optimization in Italy. The obtained efficiency is very high: 80% of waste is source separated for recycling purposes. In the second reference case, the local administration is going to be faced with the optimization of waste collection through Web-GIS oriented technologies for the first time. The starting scenario is far from an optimized management of municipal solid waste. The last two case studies concern pilot experiences in China and Malaysia. Each step of the Web-GIS oriented strategy is comparatively discussed referring to typical scenarios of developed and transient economies. The main result is that transient economies are ready to move toward Web oriented tools for MSW management, but this opportunity is not yet well exploited in the sector.

  5. Towards an Automated Acoustic Detection System for Free Ranging Elephants

    PubMed Central

    Zeppelzauer, Matthias; Hensman, Sean; Stoeger, Angela S.

    2015-01-01

    The human-elephant conflict is one of the most serious conservation problems in Asia and Africa today. The involuntary confrontation of humans and elephants claims the lives of many animals and humans every year. A promising approach to alleviate this conflict is the development of an acoustic early warning system. Such a system requires the robust automated detection of elephant vocalizations under unconstrained field conditions. Today, no system exists that fulfills these requirements. In this paper, we present a method for the automated detection of elephant vocalizations that is robust to the diverse noise sources present in the field. We evaluate the method on a dataset recorded under natural field conditions to simulate a real-world scenario. The proposed method outperformed existing approaches and robustly and accurately detected elephants. It thus can form the basis for a future automated early warning system for elephants. Furthermore, the method may be a useful tool for scientists in bioacoustics for the study of wildlife recordings. PMID:25983398

  6. Television-and-Laser Range-Measuring System

    NASA Technical Reports Server (NTRS)

    Russell, J. Kevin

    1988-01-01

    Triangulation system measures angle between two lines of sight to point on object, determining distance to object. Amenable to automation. Includes automatically aimed rotatable mirrors and laser beam to define one of lines of sight. Adjusts automatically to bring two lines of sight into convergence at common point on object.

  7. Laser-Directed Ranging System Implementing Single Camera System for Telerobotics Applications

    NASA Technical Reports Server (NTRS)

    Wells, Dennis L. (Inventor); Li, Larry C. (Inventor); Cox, Brian J. (Inventor)

    1995-01-01

    The invention relates generally to systems for determining the range of an object from a reference point and, in one embodiment, to laser-directed ranging systems useful in telerobotics applications. Digital processing techniques are employed which minimize the complexity and cost of the hardware and software for processing range calculations, thereby enhancing the commercial attractiveness of the system for use in relatively low-cost robotic systems. The system includes a video camera for generating images of the target, image digitizing circuitry, and an associated frame grabber circuit. The circuit first captures one of the pairs of stereo video images of the target, and then captures a second video image of the target as it is partly illuminated by the light beam, suitably generated by a laser. The two video images, taken sufficiently close together in time to minimize camera and scene motion, are converted to digital images and then compared. Common pixels are eliminated, leaving only a digital image of the laser-illuminated spot on the target. Mw centroid of the laser illuminated spot is dm obtained and compared with a predetermined reference point, predetermined by design or calibration, which represents the coordinate at the focal plane of the laser illumination at infinite range. Preferably, the laser and camera are mounted on a servo-driven platform which can be oriented to direct the camera and the laser toward the target. In one embodiment the platform is positioned in response to movement of the operator's head. Position and orientation sensors are used to monitor head movement. The disparity between the digital image of the laser spot and the reference point is calculated for determining range to the target. Commercial applications for the system relate to active range-determination systems, such as those used with robotic systems in which it is necessary to determine the, range to a workpiece or object to be grasped or acted upon by a robot arm end

  8. Assessment of myocardial viability.

    PubMed

    Travin, Mark I; Bergmann, Steven R

    2005-01-01

    The prevalence of left ventricular (LV) dysfunction and resultant congestive heart failure is increasing. Patients with this condition are at high risk for cardiac death and usually have significant limitations in their lifestyles. Although there have been advances in medical therapy resulting in improved survival and well being, the best and most definitive therapy, when appropriate, is revascularization. In the setting of coronary artery disease, accounting for approximately two thirds of cases of congestive heart failure, LV dysfunction often is not the result of irreversible scar but rather caused by impairment in function and energy use of still viable-myocytes, with the opportunity for improved function if coronary blood flow is restored. Patients with LV dysfunction who have viable myocardium are the patients at highest risk because of the potential for ischemia but at the same time benefit most from revascularization. It is important to identify viable myocardium in these patients, and radionuclide myocardial scintigraphy is an excellent tool for this. Single-photon emission computed tomography perfusion scintigraphy, whether using thallium-201, Tc-99m sestamibi, or Tc-99m tetrofosmin, in stress and/or rest protocols, has consistently been shown to be an effective modality for identifying myocardial viability and guiding appropriate management. Metabolic imaging with positron emission tomography radiotracers frequently adds additional information and is a powerful tool for predicting which patients will have an improved outcome from revascularization, including some patients referred instead for cardiac transplantation. Other noninvasive modalities, such as stress echocardiography, also facilitate the assessment of myocardial viability, but there are advantages and disadvantages compared with the nuclear techniques. Nuclear imaging appears to require fewer viable cells for detection, resulting in a higher sensitivity but a lower specificity than stress

  9. The prrAB Two-Component System Is Essential for Mycobacterium tuberculosis Viability and Is Induced under Nitrogen-Limiting Conditions

    PubMed Central

    Malhotra, Vandana; Cornelison, Garrett L.; Clark-Curtiss, Josephine E.

    2012-01-01

    The Mycobacterium tuberculosis prrA-prrB (Rv0903c-Rv0902c) two-component regulatory system is expressed during intracellular growth in human macrophages and is required for early intracellular multiplication in murine macrophages, suggesting its importance in establishing infection. To better understand the function of the prrA-prrB two-component system, we defined the transcriptional characteristics of the prrA and prrB genes during exponential and stationary growth and upon exposure to different environmental stresses and attempted to generate a prrA-prrB deletion mutant. The prrA and prrB genes constitute an operon and are cotranscribed during logarithmic growth, with transcriptional levels decreasing in stationary phase and during hypoxia. Despite the transcriptional differences, PrrA protein levels remained relatively stable throughout growth and in hypoxia. Under conditions of nitrogen limitation, prrAB transcription was induced, while acidic pH stress and carbon starvation did not significantly alter transcript levels. Deletion of the prrAB operon on the chromosome of M. tuberculosis H37Rv occurred only in the presence of an episomal copy of the prrAB genes, indicating that this two-component system is essential for viability. Characterization of the prrAB locus in M. tuberculosis Mt21D3, a previously described prrA transposon mutant, revealed that this strain is not a true prrA knockout mutant. Rather, Tn5367 transposon insertion into the prrA promoter only decreased prrA and prrB transcription and PrrA levels in Mt21D3 compared to those in the parental Mt103 clinical strain. These data provide the first report describing the essentiality of the M. tuberculosis prrAB two-component system and reveal insights into its potential role in mycobacterial growth and metabolism. PMID:22081401

  10. The prrAB two-component system is essential for Mycobacterium tuberculosis viability and is induced under nitrogen-limiting conditions.

    PubMed

    Haydel, Shelley E; Malhotra, Vandana; Cornelison, Garrett L; Clark-Curtiss, Josephine E

    2012-01-01

    The Mycobacterium tuberculosis prrA-prrB (Rv0903c-Rv0902c) two-component regulatory system is expressed during intracellular growth in human macrophages and is required for early intracellular multiplication in murine macrophages, suggesting its importance in establishing infection. To better understand the function of the prrA-prrB two-component system, we defined the transcriptional characteristics of the prrA and prrB genes during exponential and stationary growth and upon exposure to different environmental stresses and attempted to generate a prrA-prrB deletion mutant. The prrA and prrB genes constitute an operon and are cotranscribed during logarithmic growth, with transcriptional levels decreasing in stationary phase and during hypoxia. Despite the transcriptional differences, PrrA protein levels remained relatively stable throughout growth and in hypoxia. Under conditions of nitrogen limitation, prrAB transcription was induced, while acidic pH stress and carbon starvation did not significantly alter transcript levels. Deletion of the prrAB operon on the chromosome of M. tuberculosis H37Rv occurred only in the presence of an episomal copy of the prrAB genes, indicating that this two-component system is essential for viability. Characterization of the prrAB locus in M. tuberculosis Mt21D3, a previously described prrA transposon mutant, revealed that this strain is not a true prrA knockout mutant. Rather, Tn5367 transposon insertion into the prrA promoter only decreased prrA and prrB transcription and PrrA levels in Mt21D3 compared to those in the parental Mt103 clinical strain. These data provide the first report describing the essentiality of the M. tuberculosis prrAB two-component system and reveal insights into its potential role in mycobacterial growth and metabolism. PMID:22081401

  11. Micron-Accurate Laser Fresnel-Diffraction Ranging System

    NASA Technical Reports Server (NTRS)

    Lehner, David; Campbell, Jonathan; Smith, Kelly; Sanders, Alvin; Allison, Stephen; Smaley, Larry

    2008-01-01

    Two versions of an optoelectronic system undergoing development are depicted. The system is expected to be capable of measuring a distance between 2 and 10 m with an error of no more than 1 micrometer. The system would be designed to exploit Fresnel diffraction of a laser beam. In particular, it would be designed to take advantage of the fact that a Fresnel diffraction pattern is ultrasensitive to distance. The two versions would differ in the following respects: In version 1, the focus of the telescope would be in the Fresnel region, and the telescope would have a small depth of focus. As a consequence, the Fresnel pattern would be imaged directly onto the photodetector array; in version 2, a multielement lens module would displace the Fresnel region from the vicinity of the pinhole to the vicinity of the optical receiver. As the distance to be measured varied, the location of the receiver relative to the displaced Fresnel-diffraction region would vary, thereby causing the Fresnel diffraction pattern on the focal plane to vary. The multielement lens module would also correct for aberrations. The processing of the digitized Fresnel diffraction pattern in the computer might be accelerated by using only parts of the pattern or even only one small part - the central pixel. As the distance from the pinhole increased, the central pixel would rapidly cycle between maximum and minimum light intensity. This in itself would not be sufficient to uniquely determine the distance. However, by varying the size of the pinhole or the wavelength of the laser, one could obtain a second cycle of variation of intensity that, in conjunction with the first cycle, could enable a unique determination of distance. Alternatively, for a single wavelength and a single pinhole size, it should suffice to consider the data from only two different key pixels in the Fresnel pattern.

  12. Long-range planning for advanced European space transportation systems

    NASA Astrophysics Data System (ADS)

    Reichert, Rudi G.

    Begining in 1988, The West German Ministry for Research and Technology will conduct a five-year National Hypersonic Technology Program aimed at the development of critical components for the airbreathing, two-reusable stage transatmospheric vehicle concept designated 'Saenger'. Saenger will be alternatively capable of launching 15-ton unmanned payloads into LEO with its 'Cargus' second stage, or 5-ton manned payloads into LEO with its 'Horus' second stage. The focus of these efforts is the definition of the scramjet-based propulsion system, followed in importance by aerothermodynamic studies of the configuration and the development of suitable structures and materials.

  13. Long-range vibration detection system using heterodyne interferometry.

    PubMed

    Rzasa, John R; Cho, Kyuman; Davis, Christopher C

    2015-07-10

    We present the design and performance of an extremely sensitive coherent remote vibration detection system using optical heterodyne vibration of phase shifts produced by laser light scattered off a remote target. The resulting phase-modulated intermediate RF of 200 MHz, which carries the vibrational motion of the target, is demodulated down to baseband using an RF in-phase and quadrature demodulator. Acquisition and calculation of the target phase angle is carried out on a custom-made control board which utilizes high-resolution A/D converters, variable gain amplifiers, and a Spartan-6 field programmable gate array. PMID:26193398

  14. Zoom athermal telescope having 18.5 magnification range for 8 to 12-u range FLIR systems

    NASA Astrophysics Data System (ADS)

    Shechterman, Mark S.

    1995-10-01

    This paper describes the specific design considerations and performance evaluation for ELOP's MLZFS (modular lightweight zoom FLIR system) utilizing a new athermal wide magnification range IR zoom telescope. The following aspects of the development work are discussed in this paper: MTF and MRT characteristics of the FLIR for different temperatures; comparison with existing zoom systems and with systems of discrete magnification change; calculation of lens group positions as a function of magnification and temperature, including interpolation analyses of these dependencies; implemented methods for narcissus effect reduction at the lowest magnification mode, including development of a new AR coating; critical tolerance analyses; mechanical and electro-mechanical design, answering high accuracy requirements; adjustment and calibration of the zoom system by use of an IR interferometer.

  15. Artificial evolution by viability rather than competition.

    PubMed

    Maesani, Andrea; Fernando, Pradeep Ruben; Floreano, Dario

    2014-01-01

    Evolutionary algorithms are widespread heuristic methods inspired by natural evolution to solve difficult problems for which analytical approaches are not suitable. In many domains experimenters are not only interested in discovering optimal solutions, but also in finding the largest number of different solutions satisfying minimal requirements. However, the formulation of an effective performance measure describing these requirements, also known as fitness function, represents a major challenge. The difficulty of combining and weighting multiple problem objectives and constraints of possibly varying nature and scale into a single fitness function often leads to unsatisfactory solutions. Furthermore, selective reproduction of the fittest solutions, which is inspired by competition-based selection in nature, leads to loss of diversity within the evolving population and premature convergence of the algorithm, hindering the discovery of many different solutions. Here we present an alternative abstraction of artificial evolution, which does not require the formulation of a composite fitness function. Inspired from viability theory in dynamical systems, natural evolution and ethology, the proposed method puts emphasis on the elimination of individuals that do not meet a set of changing criteria, which are defined on the problem objectives and constraints. Experimental results show that the proposed method maintains higher diversity in the evolving population and generates more unique solutions when compared to classical competition-based evolutionary algorithms. Our findings suggest that incorporating viability principles into evolutionary algorithms can significantly improve the applicability and effectiveness of evolutionary methods to numerous complex problems of science and engineering, ranging from protein structure prediction to aircraft wing design. PMID:24489790

  16. Low pressure EGR system having full range capability

    DOEpatents

    Easley, Jr., William Lanier; Milam, David Michael; Roozenboom, Stephan Donald; Bond, Michael Steven; Kapic, Amir

    2009-09-22

    An exhaust treatment system for an engine is disclosed and may have an air induction circuit, an exhaust circuit, and an exhaust recirculation circuit. The air induction circuit may be configured to direct air into the engine. The exhaust circuit may be configured to direct exhaust from the engine and include a turbine driven by the exhaust, a particulate filter disposed in series with and downstream of the turbine, and a catalytic device disposed in series with and downstream of the particulate filter. The exhaust recirculation circuit may be configured to selectively redirect at least some of the exhaust from between the particulate filter and the catalytic device to the air induction circuit. The catalytic device is selected to create backpressure within the exhaust circuit sufficient to ensure that, under normal engine operating conditions above low idle, exhaust can flow into the air induction circuit without throttling of the air.

  17. The Development of a Digital Processing System for Accurate Range Determinations. [for Teleoperator Maneuvering Systems

    NASA Technical Reports Server (NTRS)

    Pujol, A., Jr.

    1983-01-01

    The development of an accurate close range (from 0.0 meters to 30.0 meters) radar system for Teleoperator Maneuvering Systems (TMS) is discussed. The system under investigation is a digital processor that converts incoming signals from the radar system into their related frequency spectra. Identification will be attempted by correlating spectral characteristics with accurate range determinataions. The system will utilize an analog to digital converter for sampling and converting the signal from the radar system into 16-bit digital words (two bytes) for RAM storage, data manipulations, and computations. To remove unwanted frequency components the data will be retrieved from RAM and digitally filtered using large scale integration (LSI) circuits. Filtering will be performed by a biquadratic routine within the chip which carries out the required filter algorithm. For conversion to a frequency spectrum the filtered data will be processed by a Fast Fourier Transform chip. Analysis and identification of spectral characteristics for accurate range determinations will be made by microcomputer computations.

  18. FORAGES AND PASTURES SYMPOSIUM: Improving efficiency of production in pasture- and range-based beef and dairy systems.

    PubMed

    Mulliniks, J T; Rius, A G; Edwards, M A; Edwards, S R; Hobbs, J D; Nave, R L G

    2015-06-01

    Despite overall increased production in the last century, it is critical that grazing production systems focus on improving beef and dairy efficiency to meet current and future global food demands. For livestock producers, production efficiency is essential to maintain long-term profitability and sustainability. This continued viability of production systems using pasture- and range-based grazing systems requires more rapid adoption of innovative management practices and selection tools that increase profitability by optimizing grazing management and increasing reproductive performance. Understanding the genetic variation in cow herds will provide the ability to select cows that require less energy for maintenance, which can potentially reduce total energy utilization or energy required for production, consequently improving production efficiency and profitability. In the United States, pasture- and range-based grazing systems vary tremendously across various unique environments that differ in climate, topography, and forage production. This variation in environmental conditions contributes to the challenges of developing or targeting specific genetic components and grazing systems that lead to increased production efficiency. However, across these various environments and grazing management systems, grazable forage remains the least expensive nutrient source to maintain productivity of the cow herd. Beef and dairy cattle can capitalize on their ability to utilize these feed resources that are not usable for other production industries. Therefore, lower-cost alternatives to feeding harvested and stored feedstuffs have the opportunity to provide to livestock producers a sustainable and efficient forage production system. However, increasing production efficiency within a given production environment would vary according to genetic potential (i.e., growth and milk potential), how that genetic potential fits the respective production environment, and how the grazing

  19. Laboratory test results of the high speed optical tracking system for the Spaceborne Geodynamic Ranging System

    NASA Astrophysics Data System (ADS)

    Zagwodzki, Thomas W.; White, David L.

    1987-02-01

    The high speed, high resolution optical tracking system for the Spaceborne Geodynamic Ranging System employs a two-axis gimbaled pointing device that can operate from a Space Shuttle platform and can track multiple retroreflector ground targets with arcsec accuracy. Laboratory tests of the stepping characteristics of the pointing system for various step sizes and directions has shown arcsec repeatability with little wasted motion, overshoot, or ringing. The worst rms tracking jitter was 1 and 2 arcsec in the roll and pitch axes, respectively, at the maximum tracking rate of 2 deg/sec.

  20. Laboratory test results of the high speed optical tracking system for the Spaceborne Geodynamic Ranging System

    NASA Technical Reports Server (NTRS)

    Zagwodzki, Thomas W.; White, David L.

    1987-01-01

    The high speed, high resolution optical tracking system for the Spaceborne Geodynamic Ranging System employs a two-axis gimbaled pointing device that can operate from a Space Shuttle platform and can track multiple retroreflector ground targets with arcsec accuracy. Laboratory tests of the stepping characteristics of the pointing system for various step sizes and directions has shown arcsec repeatability with little wasted motion, overshoot, or ringing. The worst rms tracking jitter was 1 and 2 arcsec in the roll and pitch axes, respectively, at the maximum tracking rate of 2 deg/sec.

  1. Viability and Resilience of Languages in Competition

    PubMed Central

    Chapel, Laetitia; Castelló, Xavier; Bernard, Claire; Deffuant, Guillaume; Eguíluz, Víctor M.; Martin, Sophie; Miguel, Maxi San

    2010-01-01

    We study the viability and resilience of languages, using a simple dynamical model of two languages in competition. Assuming that public action can modify the prestige of a language in order to avoid language extinction, we analyze two cases: (i) the prestige can only take two values, (ii) it can take any value but its change at each time step is bounded. In both cases, we determine the viability kernel, that is, the set of states for which there exists an action policy maintaining the coexistence of the two languages, and we define such policies. We also study the resilience of the languages and identify configurations from where the system can return to the viability kernel (finite resilience), or where one of the languages is lead to disappear (zero resilience). Within our current framework, the maintenance of a bilingual society is shown to be possible by introducing the prestige of a language as a control variable. PMID:20126655

  2. xCELLigence system for real-time label-free monitoring of growth and viability of cell lines from hematological malignancies

    PubMed Central

    Martinez-Serra, Jordi; Gutierrez, Antonio; Muñoz-Capó, Saúl; Navarro-Palou, María; Ros, Teresa; Amat, Juan Carlos; Lopez, Bernardo; Marcus, Toni F; Fueyo, Laura; Suquia, Angela G; Gines, Jordi; Rubio, Francisco; Ramos, Rafael; Besalduch, Joan

    2014-01-01

    The xCELLigence system is a new technological approach that allows the real-time cell analysis of adherent tumor cells. To date, xCELLigence has not been able to monitor the growth or cytotoxicity of nonadherent cells derived from hematological malignancies. The basis of its technology relies on the use of culture plates with gold microelectrodes located in their base. We have adapted the methodology described by others to xCELLigence, based on the pre-coating of the cell culture surface with specific substrates, some of which are known to facilitate cell adhesion in the extracellular matrix. Pre-coating of the culture plates with fibronectin, compared to laminin, collagen, or gelatin, significantly induced the adhesion of most of the leukemia/lymphoma cells assayed (Jurkat, L1236, KMH2, and K562). With a fibronectin substrate, nonadherent cells deposited in a monolayer configuration, and consequently, the cell growth and viability were robustly monitored. We further demonstrate the feasibility of xCELLigence for the real-time monitoring of the cytotoxic properties of several antineoplastic agents. In order to validate this technology, the data obtained through real-time cell analysis was compared with that obtained from using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide method. This provides an excellent label-free tool for the screening of drug efficacy in nonadherent cells and discriminates optimal time points for further molecular analysis of cellular events associated with treatments, reducing both time and costs. PMID:24959085

  3. Viability of Baylisascaris procyonis Eggs.

    PubMed

    Shafir, Shira C; Sorvillo, Frank J; Sorvillo, Teresa; Eberhard, Mark L

    2011-07-01

    Infection with Baylisascaris procyonis roundworms is rare but often fatal and typically affects children. We attempted to determine parameters of viability and methods of inactivating the eggs of these roundworms. Loss of viability resulted when eggs were heated to 62°C or desiccated for 7 months but not when frozen at -15°C for 6 months. PMID:21762591

  4. Viability of Baylisascaris procyonis Eggs

    PubMed Central

    Sorvillo, Frank J.; Sorvillo, Teresa; Eberhard, Mark L.

    2011-01-01

    Infection with Baylisascaris procyonis roundworms is rare but often fatal and typically affects children. We attempted to determine parameters of viability and methods of inactivating the eggs of these roundworms. Loss of viability resulted when eggs were heated to 62°C or desiccated for 7 months but not when frozen at –15°C for 6 months. PMID:21762591

  5. Light-Directed Ranging System Implementing Single Camera System for Telerobotics Applications

    NASA Technical Reports Server (NTRS)

    Wells, Dennis L. (Inventor); Li, Larry C. (Inventor); Cox, Brian J. (Inventor)

    1997-01-01

    A laser-directed ranging system has utility for use in various fields, such as telerobotics applications and other applications involving physically handicapped individuals. The ranging system includes a single video camera and a directional light source such as a laser mounted on a camera platform, and a remotely positioned operator. In one embodiment, the position of the camera platform is controlled by three servo motors to orient the roll axis, pitch axis and yaw axis of the video cameras, based upon an operator input such as head motion. The laser is offset vertically and horizontally from the camera, and the laser/camera platform is directed by the user to point the laser and the camera toward a target device. The image produced by the video camera is processed to eliminate all background images except for the spot created by the laser. This processing is performed by creating a digital image of the target prior to illumination by the laser, and then eliminating common pixels from the subsequent digital image which includes the laser spot. A reference point is defined at a point in the video frame, which may be located outside of the image area of the camera. The disparity between the digital image of the laser spot and the reference point is calculated for use in a ranging analysis to determine range to the target.

  6. Synthesis and analysis of precise spaceborne laser ranging systems, volume 2. [Spacelab payload

    NASA Technical Reports Server (NTRS)

    Paddon, E. A.

    1978-01-01

    The performance capabilities of specific shuttle-based laser ranging systems were evaluated, and interface and support requirements were determined. The preliminary design of a shuttle-borne laser ranging experiment developed as part of the Spacelab program is discussed.

  7. Geoscience Laser Ranging System - Estimated accuracy of geodetic parameters and their dependence on system characteristics

    NASA Technical Reports Server (NTRS)

    Cohen, Steven C.; Chinn, Douglas S.; Dunn, Peter J.

    1990-01-01

    Covariance analysis of the performance of the Geoscience Laser Ranging System (GLRS) indicates that three-dimensional relative positions can be recovered to an accuracy of several millimeters over spatial scales from a few kilometers to several hundred kilometers and over temporal scales as short as several days. The key factors influencing the accuracy are range noise, number of targets and their locations, system pointing capability, dwell time on the targets, orbital geometry, and gravity field uncertainties. Based on the present trade-off studies, GLRS is designed to provide range measurements with 10 mm or better accuracy, fire at a rate of 40 pulses-per-second, point over a cone extending to 50 deg from nadir, and operate with a dwell time on individual targets of 2 s or less. Given a strain rate of 10 to the -14th/s, estimated GLRS accuracy parameters suggest that the deformation can be detected in less than a month if it extends over 100 km and in less than 6 months if it extends over 10 km.

  8. Modeling methodology for MLS range navigation system errors using flight test data

    NASA Technical Reports Server (NTRS)

    Karmali, M. S.; Phatak, A. V.

    1982-01-01

    Flight test data was used to develop a methodology for modeling MLS range navigation system errors. The data used corresponded to the constant velocity and glideslope approach segment of a helicopter landing trajectory. The MLS range measurement was assumed to consist of low frequency and random high frequency components. The random high frequency component was extracted from the MLS range measurements. This was done by appropriate filtering of the range residual generated from a linearization of the range profile for the final approach segment. This range navigation system error was then modeled as an autoregressive moving average (ARMA) process. Maximum likelihood techniques were used to identify the parameters of the ARMA process.

  9. NASA ground-based and space-based laser ranging systems

    NASA Technical Reports Server (NTRS)

    Fitzmaurice, M. W.

    1977-01-01

    The development of NASA laser ranging systems is discussed with reference to applications such as orbit determination, gravity-field studies, and analyses of polar motion, earth tides, and tectonic plate motion. Several laser ranging designs are described noting the first satellite laser ranging experiment, the Moblas II and III systems, and the laser ranging satellites presently in orbit. Primary error sources are identified as atmospheric delay, optical signal-to-noise ratios, the electron multiplier, time-interval measurements, and target noise. Plans for Shuttle-based laser ranging systems are reviewed noting simulation studies of 12-day Shuttle missions.

  10. High range precision laser radar system using a Pockels cell and a quadrant photodiode

    NASA Astrophysics Data System (ADS)

    Jo, Sungeun; Kong, Hong Jin; Bang, Hyochoong; Kim, Jae-Wan; Jeon, Byoung Goo

    2016-05-01

    We have proposed and demonstrated a novel technique to measure distance with high range precision. To meet the stringent requirements of a variety of applications, range precision is an important specification for laser radar systems. Range precision in conventional laser radar systems is limited by several factors, namely laser pulse width, the bandwidth of a detector, the timing resolution of the time to digital converter, shot noise and timing jitters generated by electronics. The proposed laser radar system adopts a Pockels cell and a quadrant photodiode and only measures the energy of a laser pulse to obtain range so that the effect of those factors is reduced in comparison to conventional systems. In the proposed system, the measured range precision was 5.7 mm with 100 laser pulses. The proposed method is expected to be an alternative method for laser radar system requiring high range precision in many applications.

  11. Graphene's Viability for Fusion Applications

    NASA Astrophysics Data System (ADS)

    Navarro, Marcos; Hall, Karla; Rojas, Richard; Santarius, John; Kulcinski, Gerald

    2015-11-01

    Graphene is a source of interest for multiple applications due to its unusual electronic and physical properties. As a coating material, it has reduced oxidation of the main substrate, though no effort has been reported of testing it under fusion conditions. A number of experimental studies have established that defect-free graphene is an excellent barrier material for gases. We explore its viability to maintain a significant pressure difference under ion irradiation. Deuterium is used as a projectile on graphene coated silicon over a range of 10-50 keV energies and various fluences. The vacancy yield (amount of damage) and natural resonance for graphene are found at around 1350 cm-1 and 1550 cm-1, respectively. Damage of each sample is quantified via Raman spectroscopy (RS) using the ratio of the intensities at these wavenumbers. Graphene is also tested here as a coating for some fusion components. Though tungsten is a very promising divertor and first wall candidate, after intense irradiation, it is prone to developing fuzz or grass structures, leading to a diminished lifetime. Graphene grown on tungsten is tested under reactor conditions with 30 keV He ions at several fluences, and the sputtering of both materials is studied via RS and Scanning Electron Microscopy. This work was supported by the Graduate Engineering Research Scholars and the TEAM-Science program at the University of Wisconsin-Madison.

  12. Simulation of signal-to-noise ratio for the laser range-gated imaging system

    NASA Astrophysics Data System (ADS)

    Liang, Weiwei; Chen, Qianrong; Hao, Yongwang; Guo, Hao; Zhang, Wenpan

    2015-10-01

    The laser active imaging system is widely used in night vision, underwater imaging, three-dimension scene imaging and other civilian applications, and the system's detected range increase greatly comparing with the passive imaging system. In recent years, with rapid development of sensor and laser source technique, the laser range-gated imaging system is achieved based on high peak power pulsed laser and gated intensified CCD(ICCD), and it is well known for its properties such as high suppression of backscatter noise from fog and other obscurants, high resolution, long detection range and direct visualization. However, the performance of the laser range-gated imaging system is seriously affected by many factors, and the relationships between system's Signal-to-Noise Ratio (SNR) and influence factors are not further elaborated. In this paper, the simulation of SNR for the laser range-gated imaging system is studied. The principle of the laser range-gated imaging system is shown firstly, and the range equation is derived by means of deducing laser illuminating model according to the principle of laser radar and the characters of objects and the detectors. And then, the sources of noise are analyzed by accurately modeling all noise sources in the detection system, the model of SNR for laser range-gated imaging system is established. Finally, the relationships between SNR of system and influence factors such as gating time, laser pulse width and repetition frequency are discussed, and correspondingly the solutions are proposed.

  13. Storage Viability and Optimization Web Service

    SciTech Connect

    Stadler, Michael; Marnay, Christ; Lai, Judy; Siddiqui, Afzal; Limpaitoon, Tanachai; Phan, Trucy; Megel, Olivier; Chang, Jessica; DeForest, Nicholas

    2010-10-11

    Non-residential sectors offer many promising applications for electrical storage (batteries) and photovoltaics (PVs). However, choosing and operating storage under complex tariff structures poses a daunting technical and economic problem that may discourage potential customers and result in lost carbon and economic savings. Equipment vendors are unlikely to provide adequate environmental analysis or unbiased economic results to potential clients, and are even less likely to completely describe the robustness of choices in the face of changing fuel prices and tariffs. Given these considerations, researchers at Lawrence Berkeley National Laboratory (LBNL) have designed the Storage Viability and Optimization Web Service (SVOW): a tool that helps building owners, operators and managers to decide if storage technologies and PVs merit deeper analysis. SVOW is an open access, web-based energy storage and PV analysis calculator, accessible by secure remote login. Upon first login, the user sees an overview of the parameters: load profile, tariff, technologies, and solar radiation location. Each parameter has a pull-down list of possible predefined inputs and users may upload their own as necessary. Since the non-residential sectors encompass a broad range of facilities with fundamentally different characteristics, the tool starts by asking the users to select a load profile from a limited cohort group of example facilities. The example facilities are categorized according to their North American Industry Classification System (NAICS) code. After the load profile selection, users select a predefined tariff or use the widget to create their own. The technologies and solar radiation menus operate in a similar fashion. After these four parameters have been inputted, the users have to select an optimization setting as well as an optimization objective. The analytic engine of SVOW is LBNL?s Distributed Energy Resources Customer Adoption Model (DER-CAM), which is a mixed

  14. The Evaluation of the Regional Atmospheric Modeling System in the Eastern Range Dispersion Assessment System

    NASA Technical Reports Server (NTRS)

    Case, Jonathan

    2001-01-01

    The Applied Meteorology Unit (AMU) evaluated the Regional Atmospheric Modeling System (RAMS) contained within the Eastern Range Dispersion Assessment System (ERDAS). ERDAS provides emergency response guidance for Cape Canaveral Air Force Station and Kennedy Space Center operations in the event of an accidental hazardous material release or aborted vehicle launch. The RAMS prognostic data are available to ERDAS for display and are used to initialize the 45th Space Wing/Range Safety dispersion model. Thus, the accuracy of the dispersion predictions is dependent upon the accuracy of RAMS forecasts. The RAMS evaluation consisted of an objective and subjective component for the 1999 and 2000 Florida warm seasons, and the 1999-2000 cool season. In the objective evaluation, the AMU generated model error statistics at surface and upper-level observational sites, compared RAMS errors to a coarser RAMS grid configuration, and benchmarked RAMS against the nationally-used Eta model. In the subjective evaluation, the AMU compared forecast cold fronts, low-level temperature inversions, and precipitation to observations during the 1999-2000 cool season, verified the development of the RAMS forecast east coast sea breeze during both warm seasons, and examined the RAMS daily thunderstorm initiation and precipitation patterns during the 2000 warm season. This report summarizes the objective and subjective verification for all three seasons.

  15. Evaluation of the Regional Atmospheric Modeling System in the Eastern Range Dispersion Assessment System

    NASA Technical Reports Server (NTRS)

    Case, Jonathan

    2000-01-01

    The Applied Meteorology Unit is conducting an evaluation of the Regional Atmospheric Modeling System (RAMS) contained within the Eastern Range Dispersion Assessment System (ERDAS). ERDAS provides emergency response guidance for operations at the Cape Canaveral Air Force Station and the Kennedy Space Center in the event of an accidental hazardous material release or aborted vehicle launch. The prognostic data from RAMS is available to ERDAS for display and is used to initialize the 45th Range Safety (45 SW/SE) dispersion model. Thus, the accuracy of the 45 SW/SE dispersion model is dependent upon the accuracy of RAMS forecasts. The RAMS evaluation task consists of an objective and subjective component for the Florida warm and cool seasons of 1999-2000. The objective evaluation includes gridded and point error statistics at surface and upper-level observational sites, a comparison of the model errors to a coarser grid configuration of RAMS, and a benchmark of RAMS against the widely accepted Eta model. The warm-season subjective evaluation involves a verification of the onset and movement of the Florida east coast sea breeze and RAMS forecast precipitation. This interim report provides a summary of the RAMS objective and subjective evaluation for the 1999 Florida warm season only.

  16. Precision laser range finder system design for Advanced Technology Laboratory applications

    NASA Technical Reports Server (NTRS)

    Golden, K. E.; Kohn, R. L.; Seib, D. H.

    1974-01-01

    Preliminary system design of a pulsed precision ruby laser rangefinder system is presented which has a potential range resolution of 0.4 cm when atmospheric effects are negligible. The system being proposed for flight testing on the advanced technology laboratory (ATL) consists of a modelocked ruby laser transmitter, course and vernier rangefinder receivers, optical beacon retroreflector tracking system, and a network of ATL tracking retroreflectors. Performance calculations indicate that spacecraft to ground ranging accuracies of 1 to 2 cm are possible.

  17. Long Range Plan for Information Systems from the State Board of Education.

    ERIC Educational Resources Information Center

    Texas Education Agency, Austin.

    The Information Systems Long Range Plan specifically addresses Goal four of the Texas State Board of Education's (SBOE's) "Long-Range Plan for Public School Education" dealing with efficient management and organization of the educational system. To facilitate this goal, the SBOE in 1986 approved and directed the Texas Education Agency to implement…

  18. Economic viability of anaerobic digestion

    SciTech Connect

    Wellinger, A.

    1996-01-01

    The industrial application of anaerobic digestion is a relatively new, yet proven waste treatment technology. Anaerobic digestion reduces and upgrades organic waste, and is a good way to control air pollution as it reduces methane and nitrous gas emissions. For environmental and energy considerations, anaerobic digestion is a nearly perfect waste treatment process. However, its economic viability is still in question. A number of parameters - type of waste (solid or liquid), digester system, facility size, product quality and end use, environmental requirements, cost of alternative treatments (including labor), and interest rates - define the investment and operating costs of an anaerobic digestion facility. Therefore, identical facilities that treat the same amount and type of waste may, depending on location, legislation, and end product characteristics, reveal radically different costs. A good approach for evaluating the economics of anaerobic digestion is to compare it to treatment techniques such as aeration or conventional sewage treatment (for industrial wastewater), or composting and incineration (for solid organic waste). For example, the cost (per ton of waste) of in-vessel composting with biofilters is somewhat higher than that of anaerobic digestion, but the investment costs 1 1/2 to 2 times more than either composting or anaerobic digestion. Two distinct advantages of anaerobic digestion are: (1) it requires less land than either composting or incinerating, which translates into lower costs and milder environmental and community impacts (especially in densely populated areas); and (2) it produces net energy, which can be used to operate the facility or sold to nearby industries.

  19. Isotope Brayton electric power system for the 500 to 2500 watt range

    NASA Technical Reports Server (NTRS)

    Macosko, R. P.; Barna, G. J.; Block, H. B.; Ingle, B. D.

    1972-01-01

    An extensive study was conducted at the Lewis Research Center to evaluate an isotope Brayton electric power system for use in the 500 to 2500 W power range. Overall system simplicity was emphasized in order to reduce parasitic power losses and improve system reliability. Detailed parametric cycle analysis, conceptual component designs, and evaluation of system packaging were included. A single-loop system (gas) with six major components including one rotating unit was selected. Calculated net system efficiency varies from 23 to 28 percent over the power range.

  20. Estimate of the influence of muzzle smoke on function range of infrared system

    NASA Astrophysics Data System (ADS)

    Luo, Yan-ling; Wang, Jun; Wu, Jiang-hui; Wu, Jun; Gao, Meng; Gao, Fei; Zhao, Yu-jie; Zhang, Lei

    2013-09-01

    Muzzle smoke produced by weapons shooting has important influence on infrared (IR) system while detecting targets. Based on the theoretical model of detecting spot targets and surface targets of IR system while there is muzzle smoke, the function range for detecting spot targets and surface targets are deduced separately according to the definition of noise equivalent temperature difference(NETD) and minimum resolution temperature difference(MRTD). Also parameters of muzzle smoke affecting function range of IR system are analyzed. Base on measured data of muzzle smoke for single shot, the function range of an IR system for detecting typical targets are calculated separately while there is muzzle smoke and there is no muzzle smoke at 8~12 micron waveband. For our IR system function range has reduced by over 10% for detecting tank if muzzle smoke exists. The results will provide evidence for evaluating the influence of muzzle smoke on IR system and will help researchers to improve ammo craftwork.

  1. Method of high precision interval measurement in pulse laser ranging system

    NASA Astrophysics Data System (ADS)

    Wang, Zhen; Lv, Xin-yuan; Mao, Jin-jin; Liu, Wei; Yang, Dong

    2013-09-01

    Laser ranging is suitable for laser system, for it has the advantage of high measuring precision, fast measuring speed,no cooperative targets and strong resistance to electromagnetic interference,the measuremen of laser ranging is the key paremeters affecting the performance of the whole system.The precision of the pulsed laser ranging system was decided by the precision of the time interval measurement, the principle structure of laser ranging system was introduced, and a method of high precision time interval measurement in pulse laser ranging system was established in this paper.Based on the analysis of the factors which affected the precision of range measure,the pulse rising edges discriminator was adopted to produce timing mark for the start-stop time discrimination,and the TDC-GP2 high precision interval measurement system based on TMS320F2812 DSP was designed to improve the measurement precision.Experimental results indicate that the time interval measurement method in this paper can obtain higher range accuracy. Compared with the traditional time interval measurement system,the method simplifies the system design and reduce the influence of bad weather conditions,furthermore,it satisfies the requirements of low costs and miniaturization.

  2. One way and two way VHF ranging system performance for tracking and data relay applications

    NASA Technical Reports Server (NTRS)

    Bryan, J. W.; Filippi, C. A.

    1972-01-01

    The trajectory of an orbiting spacecraft is determined from an orbit determination program. Two inputs to this program, among others, are the range and range rate relative to some known location. The arithmetic and measurement errors in the determinations of the range, range rate, and range differences were identified and evaluated. These uncertainties are tabulated for one way and two way systems. A comparison of the measurement error contributions illustrate the predominance of thermal noise effects under low power budget conditions, with the other error sources becoming relevent for the high power budget case. The evaluated uncertainties are summarized as root sum squared noise and bias errors.

  3. Design and implementation of range-gated underwater laser imaging system

    NASA Astrophysics Data System (ADS)

    Ge, Wei-long; Zhang, Xiao-hui

    2014-02-01

    A range-gated underwater laser imaging system is designed and implemented in this article, which is made up of laser illumination subsystem, photoelectric imaging subsystem and control subsystem. The experiment of underwater target drone detection has been done, the target of distance 40m far from the range-gated underwater laser imaging system can be imaged in the pool which water attenuation coefficient is 0.159m-1. Experimental results show that the range-gated underwater laser imaging system can detect underwater objects effectively.

  4. Discussion on operating range of shipborne infrared search-and-track system

    NASA Astrophysics Data System (ADS)

    Wei, Gang; Yang, Kun-tao

    2006-02-01

    The status and effect of the optronic system in shipborne weaponry have been widely accepted, for which each developed country takes it as essential equipement in equipment developing programme. Following radar, shipborne optronic system is another important means of detection from single set to multi-set network system step by step. For reasons that shipborne IRST system can overcome four threats of radar and is an extremely effective short-range defense and countermeasure equipment for threat targets flying in low altitude and superlow altitude, so every navy has attached great importance to it. After transforming the operating range equation of an IRST system, the integrated efficiency coefficient Q is derived, by which factors of influencing the operating range of an IRST system and the approaches to improving the operating range and its feasibility are analyzed in the paper. In the present stage, because of limitations of D* the area of pixels and of an infrared detector, the major method for improving the operating range is to increase the aperture with the transmittance of an optical system remaining unchanged basically. However, increasing the aperture, remaining F number constant, increasing the focal length, reducing the effective FOV will decrease the spacial detective efficiency. So the integrated efficiency of an IRST system can be improved by optimizing the range, detective efficiency and so forth reasonably under existing conditions.

  5. Ultra-wide Range Gamma Detector System for Search and Locate Operations

    SciTech Connect

    Odell, D. Mackenzie Odell; Harpring, Larry J.; Moore, Frank S. Jr.; French, Phillip J.; Gordon, John R.

    2005-10-26

    Collecting debris samples following a nuclear event requires that operations be conducted from a considerable stand-off distance. An ultra-wide range gamma detector system has been constructed to accomplish both long range radiation search and close range hot sample collection functions. Constructed and tested on a REMOTEC Andros platform, the system has demonstrated reliable operation over six orders of magnitude of gamma dose from 100's of uR/hr to over 100 R/hr. Functional elements include a remotely controlled variable collimator assembly, a NaI(Tl)/photomultiplier tube detector, a proprietary digital radiation instrument, a coaxially mounted video camera, a digital compass, and both local and remote control computers with a user interface designed for long range operations. Long range sensitivity and target location, as well as close range sample selection performance are presented.

  6. OPO-laser system for atmospheric sounding in the mid-IR range

    NASA Astrophysics Data System (ADS)

    Romanovskii, O. A.; Kharchenko, O. V.; Kondratyuk, N. V.; Protasenya, A. L.; Shumskii, V. K.; Sadovnikov, S. A.; Yakovlev, S. V.

    2015-11-01

    A laser system is designed that provides for tunable generation of nanosecond radiation pulses in the 3-4 μm range. Optical block-diagram and specifications of the system are presented. The laser system as a part of a differential absorption lidar designed can be used for remote control of pollutant concentrations along surface atmospheric paths.

  7. Wide field of view laser beacon system for three dimensional aircraft range measurements

    NASA Technical Reports Server (NTRS)

    Wong, E. Y.

    1982-01-01

    A system that measures accurately the distance from an aircraft to a helicoper for rotor noise flight testing was developed. The system measures the range and angles between two aircraft using laser optics. This system can be applied in collision avoidance, robotics and other measurement critical tasks.

  8. Influence of range-gated intensifiers on underwater imaging system SNR

    NASA Astrophysics Data System (ADS)

    Wang, Xia; Hu, Ling; Zhi, Qiang; Chen, Zhen-yue; Jin, Wei-qi

    2013-08-01

    Range-gated technology has been a hot research field in recent years due to its high effective back scattering eliminating. As a result, it can enhance the contrast between a target and its background and extent the working distance of the imaging system. The underwater imaging system is required to have the ability to image in low light level conditions, as well as the ability to eliminate the back scattering effect, which means that the receiver has to be high-speed external trigger function, high resolution, high sensitivity, low noise, higher gain dynamic range. When it comes to an intensifier, the noise characteristics directly restrict the observation effect and range of the imaging system. The background noise may decrease the image contrast and sharpness, even covering the signal making it impossible to recognize the target. So it is quite important to investigate the noise characteristics of intensifiers. SNR is an important parameter reflecting the noise features of a system. Through the use of underwater laser range-gated imaging prediction model, and according to the linear SNR system theory, the gated imaging noise performance of the present market adopted super second generation and generation Ⅲ intensifiers were theoretically analyzed. Based on the active laser underwater range-gated imaging model, the effect to the system by gated intensifiers and the relationship between the system SNR and MTF were studied. Through theoretical and simulation analysis to the image intensifier background noise and SNR, the different influence on system SNR by super second generation and generation Ⅲ ICCD was obtained. Range-gated system SNR formula was put forward, and compared the different effect influence on the system by using two kind of ICCDs was compared. According to the matlab simulation, a detailed analysis was carried out theoretically. All the work in this paper lays a theoretical foundation to further eliminating back scattering effect, improving

  9. Resilience and vulnerability to a natural hazard: A mathematical framework based on viability theory

    NASA Astrophysics Data System (ADS)

    Rougé, Charles; Mathias, Jean-Denis; Deffuant, Guillaume

    2013-04-01

    This deals with the response of a coupled human and natural system (CHANS) to a natural hazard by using the concepts of resilience and vulnerability within the mathematical framework of viability theory. This theory applies to time-evolving systems such as CHANS and assumes that their desirable properties can be defined as a subset of their state space. Policies can also apply to influence the dynamics of such systems: viability theory aims at finding the policies which keep the properties of a controlled dynamical system for so long as no disturbance hits it. The states of the system such that the properties are guaranteed constitute what is called the viability kernel. This viability framework has been extended to describe the response to a perturbation such as a natural hazard. Resilience describes the capacity of the CHANS to recover by getting back in the viability kernel, where its properties are guaranteed until the onset of the next major event. Defined for a given controlled trajectory that the system may take after the event ends, resilience is (a) whether the system comes back to the viability kernel within a given budget such as a time constraint, but also (b) a decreasing function of vulnerability. Computed for a given trajectory as well, vulnerability is a measure of the consequence of violating a property. We propose a family of functions from which cost functions and other vulnerability indicators can be derived for a certain trajectory. There can be several vulnerability functions, representing for instance social, economic or ecological vulnerability, and each representing the violation of an associated property, but these functions need to be ultimately aggregated as a single indicator. Computing the resilience and vulnerability of a trajectory enables the viability framework to describe the response of both deterministic and stochastic systems to hazards. In the deterministic case, there is only one response trajectory for a given action policy

  10. Unifying latitudinal gradients in range size and richness across marine and terrestrial systems.

    PubMed

    Tomašových, Adam; Kennedy, Jonathan D; Betzner, Tristan J; Kuehnle, Nicole Bitler; Edie, Stewart; Kim, Sora; Supriya, K; White, Alexander E; Rahbek, Carsten; Huang, Shan; Price, Trevor D; Jablonski, David

    2016-05-11

    Many marine and terrestrial clades show similar latitudinal gradients in species richness, but opposite gradients in range size-on land, ranges are the smallest in the tropics, whereas in the sea, ranges are the largest in the tropics. Therefore, richness gradients in marine and terrestrial systems do not arise from a shared latitudinal arrangement of species range sizes. Comparing terrestrial birds and marine bivalves, we find that gradients in range size are concordant at the level of genera. Here, both groups show a nested pattern in which narrow-ranging genera are confined to the tropics and broad-ranging genera extend across much of the gradient. We find that (i) genus range size and its variation with latitude is closely associated with per-genus species richness and (ii) broad-ranging genera contain more species both within and outside of the tropics when compared with tropical- or temperate-only genera. Within-genus species diversification thus promotes genus expansion to novel latitudes. Despite underlying differences in the species range-size gradients, species-rich genera are more likely to produce a descendant that extends its range relative to the ancestor's range. These results unify species richness gradients with those of genera, implying that birds and bivalves share similar latitudinal dynamics in net species diversification. PMID:27147094

  11. LFR Demonstrator Materials Viability

    SciTech Connect

    Caro, M

    2006-08-02

    Interest in fast reactor development has increased with the Department of Energy's introduction of the Global Nuclear Energy Partnership (GNEP) [1]. The GNEP program plans development of a sodium cooled Advanced Burner Reactor (ABR) that can be used to reduce the amount spent LWR fuel in storage and the number of high level waste sites needed for expansion of nuclear power throughout the world over the 21st century. In addition, the program proposes to make nuclear power more available while reducing the proliferation concerns by revising policies and technology for control of weapons useable materials. This would be accomplished with establishment of new institutional arrangements based on selective siting of reprocessing, enrichment and waste disposal facilities. The program would also implement development of small reactors suitable for use in developing countries or remote regions with small power grids. Over the past several years, under the Department of Energy (DOE) NERI and GEN IV programs research has been conducted on small lead cooled reactors. The Small Secure Transportable Autonomous Reactor (SSTAR) [2] is the most recent version of this type of reactor and research is continuing on it in the GEN IV program in parallel with GNEP. SSTAR is a small (10MWe-100MWe) reactor that is fueled once for life. It complements the GNEP program very well in that it serves one of the world markets not currently addressed by large reactors and its development requirements are similar to those for the ABRs. In particular, the fuel and structural materials for these fast spectrum reactors share common thermal and neutron environments. The coolants, sodium in ABR and lead or lead-bismuth eutectic (LBE) in SSTAR, are the major developmental difference. This report discusses the status of structural materials for fast reactor core and primary system components and selected aspects of their development.

  12. Early experience with a highly mobile Lageos ranging system. [satellite tracking

    NASA Technical Reports Server (NTRS)

    Silverberg, E. C.; Dittmar, D.; Eanes, R.; Ricklefs, R. L.

    1981-01-01

    Two portions of the University of Texas Transportable Laser Ranging System (TLRS) are presented: the beam director and the burst mode single photon laser ranging system. The system, optimized for the Lageos target, has satellite track rates varying from approximately 1800 arcsec per sec on low targets to a few arcsec per sec on the highest. Using full aperture, approximately 3 millijoules of laser power per shot can be transmitted without exceeding the eye damage threshold, and a beam divergence of less than 30 arcsec is dictated by these parameters. Position loop response is optimized, and the instrument is capable of tracking the satellite from nearly any firm, flat position. The laser ranging system uses a multiple pulse laser, and power restrictions result in an average return of less than one photoelectron per shot. The use of a simple laser for ranging has virtually eliminated the high percentage of down time.

  13. Design and Development of High-Repetition-Rate Satellite Laser Ranging System

    NASA Astrophysics Data System (ADS)

    Choi, Eun-Jung; Bang, Seong-Cheol; Sung, Ki-Pyoung; Lim, Hyung-Chul; Jung, Chan-Gyu; Kim, In-Yeung; Choi, Jae-Seung

    2015-09-01

    The Accurate Ranging System for Geodetic Observation ? Mobile (ARGO-M) was successfully developed as the first Korean mobile Satellite Laser Ranging (SLR) system in 2012, and has joined in the International Laser Ranging Service (ILRS) tracking network, DAEdeoK (DAEK) station. The DAEK SLR station was approved as a validated station in April 2014, through the ILRS station ¡°data validation¡± process. The ARGO-M system is designed to enable 2 kHz laser ranging with millimeter-level precision for geodetic, remote sensing, navigation, and experimental satellites equipped with Laser Retroreflector Arrays (LRAs). In this paper, we present the design and development of a next generation high-repetition-rate SLR system for ARGO-M. The laser ranging rate up to 10 kHz is becoming an important issue in the SLR community to improve ranging precision. To implement high-repetition-rate SLR system, the High-repetition-rate SLR operation system (HSLR-10) was designed and developed using ARGO-M Range Gate Generator (A-RGG), so as to enable laser ranging from 50 Hz to 10 kHz. HSLR-10 includes both hardware controlling software and data post-processing software. This paper shows the design and development of key technologies of high-repetition-rate SLR system. The developed system was tested successfully at DAEK station and then moved to Sejong station, a new Korean SLR station, on July 1, 2015. HSLR-10 will begin normal operations at Sejong station in the near future.

  14. Evolution of microbial aerosol behaviour in heating, ventilating and air-conditioning systems--quantification of Staphylococcus epidermidis and Penicillium oxalicum viability.

    PubMed

    Forthomme, A; Andrès, Y; Joubert, A; Simon, X; Duquenne, P; Bemer, D; Le Coq, L

    2012-01-01

    The aim of this study was to develop an experimental set-up and a methodology to uniformly contaminate several filter samples with high concentrations of cultivable bacteria and fungi. An experimental set-up allows contaminating simultaneously up to four filters for range of velocities representative of heating, ventilating and air-conditioning systems. The test aerosol was composed of a microbial consortium of one bacterium (Staphylococcus epidermidis) and one fungus (Penicillium oxalicum) and aerosol generation was performed in wet conditions. Firstly, the experimental set-up was validated in regards to homogeneity of the air flows. The bioaerosol was also characterized in terms of the number and particle size distribution using two particle counters: optical particle counter Grimm 1.109 (optical diameters) and TSI APS 3321 (aerodynamic diameters). Moreover, stabilities of the number of particles generated were measured. Finally, concentrations of cultivable microorganisms were measured with BioSamplers SKC downstream of the four filters. PMID:23393961

  15. Evolution of microbial aerosol behaviour in heating, ventilating and air-conditioning systems--quantification of Staphylococcus epidermidis and Penicillium oxalicum viability.

    PubMed

    Forthomme, A; Andrès, Y; Joubert, A; Simon, X; Duquenne, P; Bemer, D; Le Coq, L

    2013-01-01

    The aim of this study was to develop an experimental set-up and a methodology to uniformly contaminate several filter samples with high concentrations of cultivable bacteria and fungi. An experimental set-up allows contaminating simultaneously up to four filters for range of velocities representative of heating, ventilating and air-conditioning systems. The test aerosol was composed of a microbial consortium of one bacterium (Staphylococcus epidermidis) and one fungus (Penicillium oxalicum) and aerosol generation was performed in wet conditions. Firstly, the experimental set-up was validated in regards to homogeneity of the air flows. The bioaerosol was also characterized in terms of number and particle size distribution using two particle counters: optical particle counter Grimm 1.109 (optical diameters) and TSI APS 3321 (aerodynamic diameters). Moreover, stabilities of the number of particles generated were measured. Finally, concentrations of cultivable microorganisms were measured with BioSamplers (SKC) downstream of the four filters. PMID:23837350

  16. Task path planning, scheduling and learning for free-ranging robot systems

    NASA Technical Reports Server (NTRS)

    Wakefield, G. Steve

    1987-01-01

    The development of robotics applications for space operations is often restricted by the limited movement available to guided robots. Free ranging robots can offer greater flexibility than physically guided robots in these applications. Presented here is an object oriented approach to path planning and task scheduling for free-ranging robots that allows the dynamic determination of paths based on the current environment. The system also provides task learning for repetitive jobs. This approach provides a basis for the design of free-ranging robot systems which are adaptable to various environments and tasks.

  17. Long range inhabited surface transportation system power source for the exploration of Mars (manned Mars mission)

    NASA Technical Reports Server (NTRS)

    Kohout, Lisa; Banyai, Mark; Amick, Robert

    1986-01-01

    A hydrogen-oxygen fuel cell system is identified as a viable power source for a long range inhabited surface transportation system for the exploration of Mars. Power system weights and power requirements are determined as a function of vehicle weight. For vehicles weighing from 2700 to 7300 kg in LEO, the total power system weight ranges from 1140 to 1860 kg, with the reactants and energy conversion hardware (fuel cells, reactant storage, and radiator) weighing 430 to 555 kg and 610 to 1110 kg, respectively. Vehicle power requirements range from 45 kW for a 2700 kg vehicle to 110 kW for a 7300 kg vehicle. Power system specific weights and power profiles for housekeeping and the operation of scientific equipment such as coring drills and power tools are also specified.

  18. Automation of a reclaimer using global and local range-finding systems

    NASA Astrophysics Data System (ADS)

    Ahn, Hyun S.; Choi, Chin T.; Lee, Kwan H.; Ha, Yeong-Ho

    1996-02-01

    A reclaimer is used to dig raw material from a pile and transfer it to the blast furnaces in a steel making company. We propose a range finding vision system consisting of global and local range finders to fully automate the reclaimer. A global range sensor attached to the top of the reclaimer enables scanning more than 270 degrees and detecting a three dimensional profile of a pile. The sensor uses Ladar containing a range finder and one axis scan mirror. We added a motor to rotate Ladar for another axis scanning. A height map is obtained from the acquired range data by geometric transformation. Linear interpolation is applied between neighboring range data pixels because the initial height map is represented as a group of sparsely shaped points. By thresholding and edge following, we can calculate the optimal job path which avoids overload and maximizes digging efficiency. A local range finder attached at the end of the boom detects range data between the pile and bucket. The world coordinates are computed by three-dimensional translation and rotation of local range data. The local range data is used for renewing the height map after picking up some part of the pile. In this way, we obtain pile management and reclaimer automation.

  19. Effects of Triclosan on Neural Stem Cell Viability and Survival

    PubMed Central

    Park, Bo Kyung; Gonzales, Edson Luck T.; Yang, Sung Min; Bang, Minji; Choi, Chang Soon; Shin, Chan Young

    2016-01-01

    Triclosan is an antimicrobial or sanitizing agent used in personal care and household products such as toothpaste, soaps, mouthwashes and kitchen utensils. There are increasing evidence of the potentially harmful effects of triclosan in many systemic and cellular processes of the body. In this study, we investigated the effects of triclosan in the survivability of cultured rat neural stem cells (NSCs). Cortical cells from embryonic day 14 rat embryos were isolated and cultured in vitro. After stabilizing the culture, triclosan was introduced to the cells with concentrations ranging from 1 μM to 50 μM and in varied time periods. Thereafter, cell viability parameters were measured using MTT assay and PI staining. TCS decreased the cell viability of treated NSC in a concentration-dependent manner along with increased expressions of apoptotic markers, cleaved caspase-3 and Bax, while reduced expression of Bcl2. To explore the mechanisms underlying the effects of TCS in NSC, we measured the activation of MAPKs and intracellular ROS. TCS at 50 μM induced the activations of both p38 and JNK, which may adversely affect cell survival. In contrast, the activities of ERK, Akt and PI3K, which are positively correlated with cell survival, were inhibited. Moreover, TCS at this concentration augmented the ROS generation in treated NSC and depleted the glutathione activity. Taken together, these results suggest that TCS can induce neurodegenerative effects in developing rat brains through mechanisms involving ROS activation and apoptosis initiation. PMID:26759708

  20. Effects of Triclosan on Neural Stem Cell Viability and Survival.

    PubMed

    Park, Bo Kyung; Gonzales, Edson Luck T; Yang, Sung Min; Bang, Minji; Choi, Chang Soon; Shin, Chan Young

    2016-01-01

    Triclosan is an antimicrobial or sanitizing agent used in personal care and household products such as toothpaste, soaps, mouthwashes and kitchen utensils. There are increasing evidence of the potentially harmful effects of triclosan in many systemic and cellular processes of the body. In this study, we investigated the effects of triclosan in the survivability of cultured rat neural stem cells (NSCs). Cortical cells from embryonic day 14 rat embryos were isolated and cultured in vitro. After stabilizing the culture, triclosan was introduced to the cells with concentrations ranging from 1 μM to 50 μM and in varied time periods. Thereafter, cell viability parameters were measured using MTT assay and PI staining. TCS decreased the cell viability of treated NSC in a concentration-dependent manner along with increased expressions of apoptotic markers, cleaved caspase-3 and Bax, while reduced expression of Bcl2. To explore the mechanisms underlying the effects of TCS in NSC, we measured the activation of MAPKs and intracellular ROS. TCS at 50 μM induced the activations of both p38 and JNK, which may adversely affect cell survival. In contrast, the activities of ERK, Akt and PI3K, which are positively correlated with cell survival, were inhibited. Moreover, TCS at this concentration augmented the ROS generation in treated NSC and depleted the glutathione activity. Taken together, these results suggest that TCS can induce neurodegenerative effects in developing rat brains through mechanisms involving ROS activation and apoptosis initiation. PMID:26759708

  1. A long range transmission system communication plan for ComEd of Chicago 1995 to 2000

    SciTech Connect

    Casanova, R.; Gerleve, F.J.

    1995-10-01

    The design of a telecommunication fiber optical network serving ComEd`s commercial centers and generation stations is described. A long range communication plan is presented describing a migration of transmission substation protection, monitoring and control from an analog system over power line carrier, microwave, and leased phone lines to a digital system using an optimum mix of communication channels including fiber.

  2. Loosely Coupled GPS-Aided Inertial Navigation System for Range Safety

    NASA Technical Reports Server (NTRS)

    Heatwole, Scott; Lanzi, Raymond J.

    2010-01-01

    The Autonomous Flight Safety System (AFSS) aims to replace the human element of range safety operations, as well as reduce reliance on expensive, downrange assets for launches of expendable launch vehicles (ELVs). The system consists of multiple navigation sensors and flight computers that provide a highly reliable platform. It is designed to ensure that single-event failures in a flight computer or sensor will not bring down the whole system. The flight computer uses a rules-based structure derived from range safety requirements to make decisions whether or not to destroy the rocket.

  3. Design and implementation of control system for range-gated underwater laser imaging

    NASA Astrophysics Data System (ADS)

    Ge, Wei-long; Zhang, Xiao-hui; Han, Hong-wei; Hua, Liang-hong

    2012-01-01

    There is currently considerable in developing underwater target detection, the underwater imaging system can be divided into active imaging system and passive system. The main feature of the active imaging system is that they use light sources to illuminate the targets and collect the reflection from targets. The advantages of active imaging system over passive imaging systems are high contrast and without the affection of environment sources. In this article, a range-gated underwater laser imaging system is built, which consists of laser illumination system, photoelectric imaging system and control system. The laser illumination system includes a light-pumped solid state doubled ND-YAG laser(532nm) which laser power and frequency can be adjusted and an optics expanding system of variable ratio. The photoelectric imaging system includes a gated Intensified CCD(ICCD) cameras which ICCD scheduling, gate width, delay time and gain can be adjusted and a optics received system of variable ratio. In order to acquire effectual target image using range-gated underwater laser imaging system, appropriate control parameters that include laser power and frequency, ICCD scheduling, gate width, delay time and gain, optics expanding system ratio and optics received system ratio must be given accurately. A control system which used C8051F320 and C8051F040 (MCU) as the core is designed, the control system can effectively control seven parameters that given above. The construction of software and hardware of the control system is introduced. And target image of underwater distance 25 m and 40m is given, Experimental results showed that the control system has high control precision, safe and stable operation and good speed adjusting performance can be achieved. It can be satisfied to apply to underwater target detection.

  4. Design and implementation of control system for range-gated underwater laser imaging

    NASA Astrophysics Data System (ADS)

    Ge, Wei-Long; Zhang, Xiao-Hui; Han, Hong-Wei; Hua, Liang-Hong

    2011-11-01

    There is currently considerable in developing underwater target detection, the underwater imaging system can be divided into active imaging system and passive system. The main feature of the active imaging system is that they use light sources to illuminate the targets and collect the reflection from targets. The advantages of active imaging system over passive imaging systems are high contrast and without the affection of environment sources. In this article, a range-gated underwater laser imaging system is built, which consists of laser illumination system, photoelectric imaging system and control system. The laser illumination system includes a light-pumped solid state doubled ND-YAG laser(532nm) which laser power and frequency can be adjusted and an optics expanding system of variable ratio. The photoelectric imaging system includes a gated Intensified CCD(ICCD) cameras which ICCD scheduling, gate width, delay time and gain can be adjusted and a optics received system of variable ratio. In order to acquire effectual target image using range-gated underwater laser imaging system, appropriate control parameters that include laser power and frequency, ICCD scheduling, gate width, delay time and gain, optics expanding system ratio and optics received system ratio must be given accurately. A control system which used C8051F320 and C8051F040 (MCU) as the core is designed, the control system can effectively control seven parameters that given above. The construction of software and hardware of the control system is introduced. And target image of underwater distance 25 m and 40m is given, Experimental results showed that the control system has high control precision, safe and stable operation and good speed adjusting performance can be achieved. It can be satisfied to apply to underwater target detection.

  5. Isotope Brayton electric power system for the 500 to 2500 watt range.

    NASA Technical Reports Server (NTRS)

    Macosko, R. P.; Barna, G. J.; Block, H. B.; Ingle, B. D.

    1972-01-01

    An extensive study was conducted at the Lewis Research Center to evaluate an isotope Brayton electric power system for use in the 500 to 2500 W power range. The study emphasized overall system simplicity in order to reduce parasitic power losses and improve system reliability. The study included detailed parametric cycle analysis, conceptual component designs, and evaluation of system packaging. The study has resulted in the selection of a single-loop system (gas) with six major components including one rotating unit. Calculated net system efficiency varies from 23 to 28% over the power range. The use of the Pu-238 heat source being developed for the Multi-Hundred-Watt Radioisotope Thermoelectric Generator program was assumed.

  6. Data acquisition and analysis of range-finding systems for spacing construction

    NASA Technical Reports Server (NTRS)

    Shen, C. N.

    1981-01-01

    For space missions of future, completely autonomous robotic machines will be required to free astronauts from routine chores of equipment maintenance, servicing of faulty systems, etc. and to extend human capabilities in hazardous environments full of cosmic and other harmful radiations. In places of high radiation and uncontrollable ambient illuminations, T.V. camera based vision systems cannot work effectively. However, a vision system utilizing directly measured range information with a time of flight laser rangefinder, can successfully operate under these environments. Such a system will be independent of proper illumination conditions and the interfering effects of intense radiation of all kinds will be eliminated by the tuned input of the laser instrument. Processing the range data according to certain decision, stochastic estimation and heuristic schemes, the laser based vision system will recognize known objects and thus provide sufficient information to the robot's control system which can develop strategies for various objectives.

  7. Birth, meaningful viability and abortion.

    PubMed

    Jensen, David

    2015-06-01

    What role does birth play in the debate about elective abortion? Does the wrongness of infanticide imply the wrongness of late-term abortion? In this paper, I argue that the same or similar factors that make birth morally significant with regard to abortion make meaningful viability morally significant due to the relatively arbitrary time of birth. I do this by considering the positions of Mary Anne Warren and José Luis Bermúdez who argue that birth is significant enough that the wrongness of infanticide does not imply the wrongness of late-term abortion. On the basis of the relatively arbitrary timing of birth, I argue that meaningful viability is the point at which elective abortion is prima facie morally wrong. PMID:25012846

  8. Prospecting for a Blind Geothermal System Utilizing Geologic and Geophysical Data, Seven Troughs Range, Northwestern Nevada

    NASA Astrophysics Data System (ADS)

    Forson, Corina

    To aid in the discovery and evaluation of blind resources, it is important to utilize geologic, geophysical, and geochemical techniques to find the required elements (e.g., heat source, fluid to transport the heat, and permeability in a reservoir) for geothermal energy production. Based on a regional low resistivity anomaly discovered through a reconnaissance magnetotelluric (MT) survey, detailed geologic mapping, structural analysis, and a 2 m temperature survey were conducted to delineate the most likely areas for blind geothermal activity in the Seven Troughs Range, Nevada. The Seven Troughs Range resides in the northwestern Basin and Range province 190 km northeast of Reno and 50 km northwest of Lovelock in western Nevada. There is no known geothermal system in the area. Mesozoic metasedimentary strata and intrusions dominate the northern and southern parts of the range but are nonconformably overlain by a thick sequence (~ 1.5 km) of Oligocene to Miocene volcanic and volcaniclastic rocks and Quaternary sediments in the central part of the range. The southern part of the range consists of a basement horst block bounded by two major range-front faults, with Holocene fault scarps marking the more prominent fault on the east side of the range. In contrast, several gently to moderately west-tilted fault blocks, with good exposures of the Tertiary volcanic strata and bounded by a series of steeply east-dipping normal faults, characterize the central part of the range. Kinematic analysis of faults in the range and regional relations indicate a west-northwest-trending extension direction. Accordingly, slip and dilation tendency analyses suggest that north-northeast striking faults are the most favorably oriented for reactivation and fluid flow under the current stress field. Two areas in the Seven Troughs Range have a favorable structural setting for generating permeability and channeling geothermal fluids to the near surface: 1) A major right step in the range

  9. A high resolution laser ranging system based on time-correlated single-photon counting technology

    NASA Astrophysics Data System (ADS)

    Yang, Yixin; Wang, Huanqin; Huang, Zhe; Cao, Yangyang; Gui, Huaqiao

    2014-12-01

    Laser ranging has become an important method for both distance measurements and acquisition of threedimensional (3D) images. In this paper, a laser ranging system based on Time-Correlated Single-Photon Counting technology (TCSPC) is developed. A Geiger-mode avalanche photodiode (G-APD), which has the ability of detecting single-photon events, is used to capture the weak light scattered from the long-range target. In order to improve the ranging resolution of TCSPC based measurement system, a high repetition frequency of subnanosecond narrow pulse generator circuit based on the avalanche effect of RF-BJT is designed and applied as the light source. Moreover, some optimized optical light designs have been done to improve the system signal to noise rate (SNR), including using a special aspherical lens as projecting lens, adopting a telephoto camera lens with small view angle and short depth of field before detector. Experimental tests for evaluation of the laser raging system performance are described. As a means of echo signal analysis, three different algorithms have been introduced, in which the cross-correlation algorithm was demonstrated to be the most effective algorithm to determining the round trip time to a target, even based on histograms with a significant amount of background noise photons. It was found that centimeter ranging resolution can be achieved thanks to the use of Time-to-Digital Converter (TDC) with picosecond resolution and the Cross-Correlation algorithm. The proposed laser ranging system has advantages of high range resolution, short response time and simple structure, which was potential applications for 3D object recognition, computer vision, reverse engineering and virtual reality.

  10. Effect of the short-range interaction on critical phenomena in elastic interaction systems

    NASA Astrophysics Data System (ADS)

    Nishino, Masamichi; Miyashita, Seiji

    2013-07-01

    The elastic interaction, induced by the lattice distortion due to the difference of the molecular size, causes an effective long-range interaction. In spin-crossover (SC) compounds, local bistable states, i.e., high-spin and low-spin states, have different molecular sizes, and the elastic interaction is important. In bipartite lattices, e.g., the square lattice, the ground state can be two types of phases: ferromagneticlike and antiferromagneticlike phases. In systems like SC compounds, the former phase consists of all small or large molecules, and the latter phase has the configuration of alternating small and large molecules. In fact, both cases are observed in SC systems. In this paper we have studied the effect of the short-range interaction in the elastic system on the properties of those order-disorder phase transitions. We have obtained a phase diagram in the coordinates of the temperature and the strength of the short-range interaction, including the metastable structures. We show that effects of the short-range interaction are essentially different for ferromagneticlike and antiferromagneticlike phase transitions. In the ferromagneticlike transition, the long-range interaction of elasticity is relevant, and the system exhibits a phase transition in the mean-filed universality class. In this case, the long-range interaction strongly enhances the ferromagneticlike order, and it works cooperatively with the short-range interaction. In contrast, in the antiferromagneticlike transition, the elastic interaction slightly enhances the antiferromagneticlike order, but essentially it does not contribute to the ordering, and the system shows a transition in the Ising universality class. We have found that in the border region between ferromagneticlike and antiferromagneticlike phases, the antiferromagneticlike phase has an advantage at finite temperatures. We discuss the critical properties of two-step SC transitions with comparison between the elastic interaction

  11. a Pre-Emphasis Technique to Broaden the Usable Frequency Range in Swept-Frequency Systems

    NASA Astrophysics Data System (ADS)

    Gammell, Paul M.; Maruvada, Subha; Liu, Yunbo; Harris, Gerald R.

    2010-02-01

    The usable frequency range of an ultrasonic swept-frequency system can be compromised because of transducer bandwidth limitations or sample frequency response and corresponding signal-to-noise (S/N) considerations. By adding a variable gain amplifier together with an arbitrary waveform generator that is synchronized with the frequency sweep, the dynamic range of the receiver can be accommodated over a wider frequency range. This pre-emphasis approach has been demonstrated for two applications: substitution calibration of hydrophones and attenuation measurements.

  12. Range-separated double-hybrid density-functional theory applied to periodic systems

    SciTech Connect

    Sansone, Giuseppe; Civalleri, Bartolomeo; Maschio, Lorenzo; Usvyat, Denis; Toulouse, Julien; Sharkas, Kamal

    2015-09-14

    Quantum chemistry methods exploiting density-functional approximations for short-range electron-electron interactions and second-order Møller-Plesset (MP2) perturbation theory for long-range electron-electron interactions have been implemented for periodic systems using Gaussian-type basis functions and the local correlation framework. The performance of these range-separated double hybrids has been benchmarked on a significant set of systems including rare-gas, molecular, ionic, and covalent crystals. The use of spin-component-scaled MP2 for the long-range part has been tested as well. The results show that the value of μ = 0.5 bohr{sup −1} for the range-separation parameter usually used for molecular systems is also a reasonable choice for solids. Overall, these range-separated double hybrids provide a good accuracy for binding energies using basis sets of moderate sizes such as cc-pVDZ and aug-cc-pVDZ.

  13. An LED-array-based range imaging system used for enhancing three-dimensional imaging

    NASA Astrophysics Data System (ADS)

    Wang, Huanqin; Xu, Jun; He, Deyong; Zhao, Tianpeng; Wang, Anting; Ming, Hai; Kong, Deyi

    2010-11-01

    An LED-array-based range imaging system is proposed for three-dimensional (3-D) shape measurement. The range image is obtained by time-division electronic scanning of the LED Time-of-Flight (TOF) range finders in array, and no complex mechanical scanning is needed. By combining with a low cost CCD/CMOS sensor for capturing the twodimensional (2-D) image, the proposed range imaging system can be used to accomplish a high quality 3-D imaging. A sophisticated co-lens optical path is designed to assure the natural registration between the range image and 2-D image. Experimental tests for evaluation of the imaging system performance are described. It was found that the 3-D images can be acquired at a rate of 10 frames per second with a depth resolution better than 5mm in the range of 50 - 1000mm, which is sufficient for many practical applications, including the obstacle detection in robotics, machine automation, 3-D vision, virtual reality games and 3-D video.

  14. A Newly Developed X-Y Planar Nano-Motion Table System with Large Travel Ranges

    NASA Astrophysics Data System (ADS)

    Kurisaki, Yugo; Sawano, Hiroshi; Yoshioka, Hayato; Shinno, Hidenori

    Precision motion control technology has been widely used in high accuracy applications such as advanced scientific instruments and semiconductor fabrication equipment. In particular, the nano-motion control system with multiple degrees of freedom positioning in large travel ranges has been required in the field of precision engineering. In order to realize such a system, it is necessary and indispensable to develop a planar motion table system based on a new design concept. This paper presents a newly developed X-Y planar nano-motion table system with large travel ranges. This system is composed of a fine motion table and a coarse motion mechanism. The fine motion table is supported by porous aerostatic bearings and driven by voice coil motors with a laser interferometer feedback in a perfect non-contact condition. In addition, the table is driven at the center of gravity during the X-Y planar motion. The coarse motion mechanism has the frame structure with the coils of voice coil motors for the fine motion table. In order to enlarge the table travel ranges, the coarse motion mechanism follows the fine table motion. Performance evaluation results confirm that the developed table system has a remarkable performance which includes nanometer positioning capability over large travel ranges.

  15. Attractor nonequilibrium stationary states in perturbed long-range interacting systems

    NASA Astrophysics Data System (ADS)

    Joyce, Michael; Morand, Jules; Viot, Pascal

    2016-05-01

    Isolated long-range interacting particle systems appear generically to relax to nonequilibrium states ("quasistationary states" or QSSs) which are stationary in the thermodynamic limit. A fundamental open question concerns the "robustness" of these states when the system is not isolated. In this paper we explore, using both analytical and numerical approaches to a paradigmatic one-dimensional model, the effect of a simple class of perturbations. We call them "internal local perturbations" in that the particle energies are perturbed at collisions in a way which depends only on the local properties. Our central finding is that the effect of the perturbations is to drive all the very different QSSs we consider towards a unique QSS. The latter is thus independent of the initial conditions of the system, but determined instead by both the long-range forces and the details of the perturbations applied. Thus in the presence of such a perturbation the long-range system evolves to a unique nonequilibrium stationary state, completely different from its state in absence of the perturbation, and it remains in this state when the perturbation is removed. We argue that this result may be generic for long-range interacting systems subject to perturbations which are dependent on the local properties (e.g., spatial density or velocity distribution) of the system itself.

  16. On computation of stabilizing loop gain and delay ranges for bi-proper delay systems.

    PubMed

    Le, Binh Nguyen; Wang, Qing-Guo; Lee, Tong Heng; Nie, Zhuoyun

    2014-11-01

    A graphical method for exactly computing the stabilizing loop gain and delay ranges was proposed [Le BN, Wang Q-G, Lee T-H. Development of D-decomposition method for computing stabilizing gain ranges for general delay systems. J Process Control 2012] for a strictly proper process by determining the boundary functions which may change system׳s stability. A bi-proper process is rare but causes great complications for the method, due to the new phenomena that do not exist for a strictly proper process, such as a non-zero gain at infinity frequency, which may cause infinite intersections of boundary functions within a finite delay range. This paper addresses such a kind of processes and develops a general method that can produce the exact and complete set of the loop gain and delay for closed-loop stabilization, which is hard to find with analytical methods. PMID:25440948

  17. Optimizing the dynamic range extension of a radiochromic film dosimetry system

    SciTech Connect

    Devic, Slobodan; Tomic, Nada; Soares, Christopher G.; Podgorsak, Ervin B.

    2009-02-15

    The authors present a radiochromic film dosimetry protocol for a multicolor channel radiochromic film dosimetry system consisting of the external beam therapy (EBT) model GAFCHROMIC film and the Epson Expression 1680 flat-bed document scanner. Instead of extracting only the red color channel, the authors are using all three color channels in the absorption spectrum of the EBT film to extend the dynamic dose range of the radiochromic film dosimetry system. By optimizing the dose range for each color channel, they obtained a system that has both precision and accuracy below 1.5%, and the optimized ranges are 0-4 Gy for the red channel, 4-50 Gy for the green channel, and above 50 Gy for the blue channel.

  18. An emittance measurement system for a wide range of bunch charges

    SciTech Connect

    Dunham, B.; Engwall, D.; Hofler, A.; Keesee, M.; Legg, R.

    1997-06-01

    As a part of the emittance measurements planned for the FEL injector at the Thomas Jefferson National Accelerator Facility (Jefferson Lab), the authors have developed an emittance measurement system that covers the wide dynamic range of bunch charges necessary to fully characterize the high-DC-voltage photocathode gun. The measurements are carried out with a variant of the classical two-slit method using a slit to sample the beam in conjunction with a wire scanner to measure the transmitted beam profile. The use of commercial, ultra-low noise picoammeters makes it possible to cover the wide range of desired bunch charges, with the actual measurements made over the range of 0.25 pC to 125 pC. The entire system, including its integration into the EPICS control system, is discussed.

  19. Optimal performance receiving ranging system model and realization using TCSPC technique

    NASA Astrophysics Data System (ADS)

    Shen, Shanshan; Chen, Qian; He, Weiji; Zhou, Pin; Gu, Guohua

    2015-10-01

    In this paper, the short dead time detection probability is introduced to the linear SNR model of fixed frequency multipulse accumulation detection system. Monte Carlo simulation is consistent with the theory simulation, which proves that with the increased laser power, the SNR first gets larger quickly and then becomes stable. Then the range standard deviation model is settled and firstly shows that larger dead time brings better range precision, which is consistent with the B. I. Cantor's research. Secondly, Monte Carlo simulation and theory simulation both indicate that with the increased laser power, range precision first enhances and then becomes stable. Experimental results show that based on 500000c/s high background noise, the maximum of SNR can be obtained with emitting laser power at about 400uw at 50ms integrated time. Range precision reaches the optimal level at 6mm. The experimental data show a precision which is always worse than the Monte Carlo simulated results. This arises from the fact that the histograms' jitter is not taking into account and introduced during simulation, whereas the experimental system has approximately 500ps' jitter. The system jitter causes larger time stamp value fluctuation, leading to worse range precision. To sum up, theory and experiment all prove that the optimal performance receiving of SNR and precision is achieved on this multi-pulse accumulation detection system.

  20. A technique for remotely measuring surface pressure from a satellite using a multicolor laser ranging system

    NASA Technical Reports Server (NTRS)

    Gardner, C. S.

    1979-01-01

    The optical path length from a satellite to the earth's surface is strongly dependent on the atmospheric pressure along the propagation path. Surface pressure can be measured by using a multicolor laser ranging system to observe the change with wavelength in the optical path length from the satellite to a ground target. The equations which relate surface pressure to the differential path lengths are derived and the accuracy of the pressure measurement is evaluated in terms of the ranging system parameters. The results indicate that pressure accuracies of a few millibars appear feasible.

  1. Technique for remotely measuring surface pressure from a satellite using a multicolor laser ranging system

    NASA Technical Reports Server (NTRS)

    Gardner, C. S.

    1979-01-01

    The optical path length from a satellite to the earth's surface is strongly dependent on the atmospheric pressure along the propagation path. It is shown that surface pressures can be measured by the use of a multicolor laser ranging system to observe the change with wavelength in the optical path length from the satellite to a ground target. Equations are derived which relate surface pressure to the differential path lengths. In addition, the accuracy of the pressure measurement is evaluated in terms of the ranging system parameters. It is concluded that the results indicate that pressure accuracies of a few millibars appear feasible.

  2. Pulsed multiwavelength laser ranging system. Ph.D. Thesis - Maryland Univ.

    NASA Technical Reports Server (NTRS)

    Abshire, J. B.

    1982-01-01

    A pulsed multiwavelength laser ranging system for measuring atmospheric delay was built and tested, and its theoretical performance limits were calculated. The system uses a dye modelocked ND:YAG laser, which transmits 70 psec wide pulses simultaneously at 1064, 532, and 355 nm. The differential delay of the 1064 and 355 nm pulses is measured by a specially calibrated waveform digitizer to estimate the dry atmospheric delay. The delay time of the 532 nm pulse is used to measure the target distance. Static crossed field photomultipliers are used as detectors for all wavelengths. Theoretical analysis shows that path curvature and atmospheric turbulence are fundamental limits to the ranging accuracy of both single and multicolor systems operating over horizontal paths. For two color systems, an additional error is caused by the uncertainty in the path averaged water vapor. The standard deviation of the multicolor instrument's timing measurements is directly proportional to the laser pulse width plus photomultiplier jitter divided by the square root of the received photoelectron number. The prototype system's maximum range is km, which is limited by atmospheric and system transmission losses at 355 nm. System signal detection and false alarm calculations are also presented.

  3. Single-plane versus three-plane methods for relative range error evaluation of medium-range 3D imaging systems

    NASA Astrophysics Data System (ADS)

    MacKinnon, David K.; Cournoyer, Luc; Beraldin, J.-Angelo

    2015-05-01

    Within the context of the ASTM E57 working group WK12373, we compare the two methods that had been initially proposed for calculating the relative range error of medium-range (2 m to 150 m) optical non-contact 3D imaging systems: the first is based on a single plane (single-plane assembly) and the second on an assembly of three mutually non-orthogonal planes (three-plane assembly). Both methods are evaluated for their utility in generating a metric to quantify the relative range error of medium-range optical non-contact 3D imaging systems. We conclude that the three-plane assembly is comparable to the single-plane assembly with regard to quantification of relative range error while eliminating the requirement to isolate the edges of the target plate face.

  4. [Nicotinamide influence on pancreatic cells viability].

    PubMed

    Kuchmerovs'ka, T M; Donchenko, H V; Tykhonenko, T M; Huzyk, M M; Stavniĭchuk, R V; Ianits'ka, L V; Stepanenko, S P; Klymenko, A P

    2012-01-01

    The study was undertaken to investigate the modulating effect of nicotinamide (NAm) in different concentrations and under different glucose concentrations on the viability and oxidative stress induced by streptozotocin (STZ, 5 mmol/l) and hydrogen peroxide (H2O2, 100 micromol/l) on isolated rat pancreatic cells of the Langerhans islets in vitro. Cell viability did not depend on the concentration of glucose in the range of 5-20 mmol/l, and in subsequent studies we used glucose in concentration of 10 mmol/l to protect cells against its hypo- and hyperglycemic action. Cytoprotective effect of NAm in concentrations from 5 to 20 mmol/l on cells survival was the same. It was found that the destructive action of STZ and H2O2 during 24 hours on isolated cells of the pancreas resulted in the significant cell death. It was revealed that NAm in concentration of 5 mmol/l not only had cytoprotective effects against STZ and H2O2 but also partially reduced the level of oxidative stress in the investigated cells induced by these compounds. High concentration of NAm, 35 mmol/l, causes cytotoxic effect on the viability of pancreatic islet cells and increase of oxidative stress induced by STZ and H2O2. Most likely these effects could be associated with direct modulatory action of NAm on important effector mechanisms involved in cell death, including PARP-dependent processes, or/and indirectly, through metabolic and antioxidant effects of the compound. PMID:22642125

  5. The effects of short-term hypoxia on human mesenchymal stem cell proliferation, viability and p16INK4A mRNA expression: Investigation using a simple hypoxic culture system with a deoxidizing agent

    PubMed Central

    Ito, Akira; Aoyama, Tomoki; Yoshizawa, Makoto; Nagai, Momoko; Tajino, Junichi; Yamaguchi, Shoki; Iijima, Hirotaka; Zhang, Xiangkai; Kuroki, Hiroshi

    2015-01-01

    A hypoxic environment is thought to be important for the maintenance of stemness and suppressing cell senescence, in stem cells. Therefore, a hypoxic condition is induced during cell expansion and/or induction of intended differentiation. However, the induction of these conditions requires a specially equipped hypoxia chamber and expensive gas mixtures, which are expensive and space-consuming. Owing to these restrictions, appropriate hypoxic conditions cannot be provided during cell transportation, which is increasingly required for regenerative medicine. Hence, a simple and economical culture system is required. The purpose of this study was to investigate the effects of short-term hypoxic conditions on human mesenchymal stem cell (MSC) proliferation, viability, and senescence, utilizing the CulturePal system (CulturePal-Zero and CulturePal-Five), a novel and simple hypoxic culture system with a built-in deoxidizing agent. The O2 concentration in the CulturePal-Zero was observed to reduce to <0.1% within 1 h, and to 5% within 24h in the CulturePal-Five system. Cell proliferation under these hypoxic conditions showed a sharp increase at 5% O2 concentration, and no noticeable cell death was observed even at severe hypoxic conditions (<0.1% O2) up to 72h. The p16INK4A (cell senescence marker) mRNA expression was retained under hypoxic conditions up to 72h, but it was up-regulated under normoxic conditions. Interestingly, the p16INK4A expression altered proportionately to the O2 concentration. These results indicated that the short-term hypoxic condition, at an approximate O2 concentration of 5%, would be suitable for promoting cell proliferation and repressing cell senescence, without aggravating the MSC viability. Therefore, the CulturePal systems may be suitable for providing an appropriate hypoxic condition in stem cell research and transportation. PMID:26195892

  6. Studies for determining the optimum propulsion system characteristics for use in a long range transport aircraft

    NASA Technical Reports Server (NTRS)

    Brines, G. L.

    1972-01-01

    A comprehensive evaluation of propulsion systems for the next generation of near-sonic long range transport aircraft indicates that socially responsive noise and emission goals can be achieved within the probable limits of acceptable airplane performance and economics. Technology advances needed in the 1975-1985 time period to support the development of these propulsion systems are identified and discussed. The single most significant result is the low noise, high performance potential of a low tip speed, spaced, two-stage fan.

  7. Universalities for the Efimov-favored system with finite-range interactions

    NASA Astrophysics Data System (ADS)

    Wu, Meng-Shan; Han, Hui-Li; Shi, Ting-Yun

    2016-06-01

    Universal properties of Efimov states for some triatomic systems composed by one light and two heavy atoms are investigated using the finite-range model potentials. We have successfully obtained accurate values of binding energies and sizes for three successive Efimov states. Compared with the predicted scaling constants of the zero-range theory, the ground Efimov states are found to have the largest finite-range corrections. There exists a universal size-binding momentum relation for Efimov states which can be described by the formula Rn*kn*=√{(1 +s02)/3 } derived with zero-range approximation. It is found that for the Efimov states that have large scaled sizes, their size-binding momentum relations follow the universal formula well. Our calculations demonstrate that size is an important characteristic in determining the universalities of Efimov states.

  8. Robust Range Estimation with a Monocular Camera for Vision-Based Forward Collision Warning System

    PubMed Central

    2014-01-01

    We propose a range estimation method for vision-based forward collision warning systems with a monocular camera. To solve the problem of variation of camera pitch angle due to vehicle motion and road inclination, the proposed method estimates virtual horizon from size and position of vehicles in captured image at run-time. The proposed method provides robust results even when road inclination varies continuously on hilly roads or lane markings are not seen on crowded roads. For experiments, a vision-based forward collision warning system has been implemented and the proposed method is evaluated with video clips recorded in highway and urban traffic environments. Virtual horizons estimated by the proposed method are compared with horizons manually identified, and estimated ranges are compared with measured ranges. Experimental results confirm that the proposed method provides robust results both in highway and in urban traffic environments. PMID:24558344

  9. A fuzzy-split range control system applied to a fermentation process.

    PubMed

    Fonseca, Rodolpho Rodrigues; Schmitz, Jones Erni; Fileti, Ana Maria Frattini; da Silva, Flavio Vasconcelos

    2013-08-01

    In this study it was proposed the application of a fuzzy-PI controller in tandem with a split range control strategy to regulate the temperature inside a fermentation vat. Simulations were carried out using different configurations of fuzzy controllers and split range combinations for regulatory control. The performance of these control systems were compared using conventional integral of error criteria, the demand of utilities and the control effort. The proposed control system proved able to adequately regulate the temperature in all the tests. Besides, considering a similar ITAE index and using the energetically most efficient split range configuration, fuzzy-PI controller provided a reduction of approximately 84.5% in the control effort and of 6.75% in total demand of utilities by comparison to a conventional PI controller. PMID:23759431

  10. Relative lateration across the Los Angeles basin using a satellite laser ranging system

    NASA Technical Reports Server (NTRS)

    Silverberg, E. C.; Cahill, T.; Dorman, J.

    1982-01-01

    In January of 1981 the Transportable Laser Ranging System (TLRS) developed for NASA by the University of Texas was used to conduct a four-day test of the relative lateration technique. The test evolved making repeated measurements of six lines over the Los Angeles basin varying in distance from 26 to 84 kilometers. Although the raw times-of-flight to the various targets changed typically by 5 parts in 10 to the 6th, their line ratios varied nearly an order of magnitude less. The test suggests that the TLRS or other pulsed laser ranging systems might be able to economically combine Lageos ranging and long baseline horizontal work to survey large areas for accumulating crustal strain.