Sample records for reaktora tipa vvehr-1000

  1. Neutral ligand TIPA-based two 2D metal-organic frameworks: ultrahigh selectivity of C2H2/CH4 and efficient sensing and sorption of Cr(vi ).

    PubMed

    Fu, Hong-Ru; Zhao, Ying; Zhou, Zhan; Yang, Xiao-Gang; Ma, Lu-Fang

    2018-03-12

    One neutral tripodal semi-rigidity ligand tri(4-imidazolylphenyl)amine (TIPA) with excellent hole-transfer nature, was selected as a linker to construct MOFs. Two two-dimensional (2D) microporous metal-organic frameworks (MOFs) were synthesized solvothermally: [Ni(TIPA)(COO - ) 2 (H 2 O)]·2(DMF)2(H 2 O) (1) and [Cd(TIPA) 2 (ClO 4 - ) 2 ]·(DMF)3(H 2 O) (2). Compound 1 incorporated carboxylic groups into the channel and exhibited the high capacity of light hydrocarbons as well as the remarkable selectivity of C 2 H 2 /CH 4 . The value is in excess of 100 at room temperature, which is the highest value reported to date. Compound 2, as a cationic framework with high water stability, was not only applied as a sensor, displaying the ultrahigh sensitivity against Cr 2 O 7 2- with a detection limit as low as 8 ppb, but also possessed excellent Cr(vi) sorption with good repeatability in aqueous solution. This study provides an efficient strategy to design cationic MOFs for the selective separation of light hydrocarbons and the sensing and trapping of toxic chromate for the purification of water.

  2. 7 CFR 1000.91-1000.92 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true [Reserved] 1000.91-1000.92 Section 1000.91-1000.92 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Miscellaneous Provisions §§ 1000.91-1000.92 [Reserved] ...

  3. DDG-1000 Zumwalt Class Destroyer (DDG-1000)

    DTIC Science & Technology

    2015-12-01

    Selected Acquisition Report ( SAR ) RCS: DD-A&T(Q&A)823-197 DDG 1000 Zumwalt Class Destroyer (DDG 1000) As of FY 2017 President’s Budget Defense...Acquisition Management Information Retrieval (DAMIR) March 23, 2016 15:17:06 UNCLASSIFIED DDG 1000 December 2015 SAR March 23, 2016 15:17:06...Requirements Document OSD - Office of the Secretary of Defense O&S - Operating and Support PAUC - Program Acquisition Unit Cost DDG 1000 December 2015 SAR

  4. L1000CDS2: LINCS L1000 characteristic direction signatures search engine.

    PubMed

    Duan, Qiaonan; Reid, St Patrick; Clark, Neil R; Wang, Zichen; Fernandez, Nicolas F; Rouillard, Andrew D; Readhead, Ben; Tritsch, Sarah R; Hodos, Rachel; Hafner, Marc; Niepel, Mario; Sorger, Peter K; Dudley, Joel T; Bavari, Sina; Panchal, Rekha G; Ma'ayan, Avi

    2016-01-01

    The library of integrated network-based cellular signatures (LINCS) L1000 data set currently comprises of over a million gene expression profiles of chemically perturbed human cell lines. Through unique several intrinsic and extrinsic benchmarking schemes, we demonstrate that processing the L1000 data with the characteristic direction (CD) method significantly improves signal to noise compared with the MODZ method currently used to compute L1000 signatures. The CD processed L1000 signatures are served through a state-of-the-art web-based search engine application called L1000CDS 2 . The L1000CDS 2 search engine provides prioritization of thousands of small-molecule signatures, and their pairwise combinations, predicted to either mimic or reverse an input gene expression signature using two methods. The L1000CDS 2 search engine also predicts drug targets for all the small molecules profiled by the L1000 assay that we processed. Targets are predicted by computing the cosine similarity between the L1000 small-molecule signatures and a large collection of signatures extracted from the gene expression omnibus (GEO) for single-gene perturbations in mammalian cells. We applied L1000CDS 2 to prioritize small molecules that are predicted to reverse expression in 670 disease signatures also extracted from GEO, and prioritized small molecules that can mimic expression of 22 endogenous ligand signatures profiled by the L1000 assay. As a case study, to further demonstrate the utility of L1000CDS 2 , we collected expression signatures from human cells infected with Ebola virus at 30, 60 and 120 min. Querying these signatures with L1000CDS 2 we identified kenpaullone, a GSK3B/CDK2 inhibitor that we show, in subsequent experiments, has a dose-dependent efficacy in inhibiting Ebola infection in vitro without causing cellular toxicity in human cell lines. In summary, the L1000CDS 2 tool can be applied in many biological and biomedical settings, while improving the extraction of

  5. L1000CDS2: LINCS L1000 characteristic direction signatures search engine

    PubMed Central

    Duan, Qiaonan; Reid, St Patrick; Clark, Neil R; Wang, Zichen; Fernandez, Nicolas F; Rouillard, Andrew D; Readhead, Ben; Tritsch, Sarah R; Hodos, Rachel; Hafner, Marc; Niepel, Mario; Sorger, Peter K; Dudley, Joel T; Bavari, Sina; Panchal, Rekha G; Ma’ayan, Avi

    2016-01-01

    The library of integrated network-based cellular signatures (LINCS) L1000 data set currently comprises of over a million gene expression profiles of chemically perturbed human cell lines. Through unique several intrinsic and extrinsic benchmarking schemes, we demonstrate that processing the L1000 data with the characteristic direction (CD) method significantly improves signal to noise compared with the MODZ method currently used to compute L1000 signatures. The CD processed L1000 signatures are served through a state-of-the-art web-based search engine application called L1000CDS2. The L1000CDS2 search engine provides prioritization of thousands of small-molecule signatures, and their pairwise combinations, predicted to either mimic or reverse an input gene expression signature using two methods. The L1000CDS2 search engine also predicts drug targets for all the small molecules profiled by the L1000 assay that we processed. Targets are predicted by computing the cosine similarity between the L1000 small-molecule signatures and a large collection of signatures extracted from the gene expression omnibus (GEO) for single-gene perturbations in mammalian cells. We applied L1000CDS2 to prioritize small molecules that are predicted to reverse expression in 670 disease signatures also extracted from GEO, and prioritized small molecules that can mimic expression of 22 endogenous ligand signatures profiled by the L1000 assay. As a case study, to further demonstrate the utility of L1000CDS2, we collected expression signatures from human cells infected with Ebola virus at 30, 60 and 120 min. Querying these signatures with L1000CDS2 we identified kenpaullone, a GSK3B/CDK2 inhibitor that we show, in subsequent experiments, has a dose-dependent efficacy in inhibiting Ebola infection in vitro without causing cellular toxicity in human cell lines. In summary, the L1000CDS2 tool can be applied in many biological and biomedical settings, while improving the extraction of knowledge

  6. 7 CFR 3017.1000 - Respondent.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Respondent. 3017.1000 Section 3017.1000 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 3017.1000 Respondent...

  7. 40 CFR 725.1000 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Scope. 725.1000 Section 725.1000 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT REPORTING....1000 Scope. This subpart identifies uses of microorganisms which EPA has determined to be significant...

  8. 22 CFR 1006.1000 - Respondent.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Respondent. 1006.1000 Section 1006.1000 Foreign Relations INTER-AMERICAN FOUNDATION GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 1006.1000 Respondent. Respondent means a person against whom an agency has initiated a debarment or...

  9. 29 CFR 1471.1000 - Respondent.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Respondent. 1471.1000 Section 1471.1000 Labor Regulations Relating to Labor (Continued) FEDERAL MEDIATION AND CONCILIATION SERVICE GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 1471.1000 Respondent. Respondent means a person against whom an...

  10. 7 CFR 760.1000 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Applicability. 760.1000 Section 760.1000 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE... Catfish Grant Programs § 760.1000 Applicability. (a) This subpart establishes the terms and conditions...

  11. 22 CFR 1508.1000 - Respondent.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Respondent. 1508.1000 Section 1508.1000 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 1508.1000 Respondent. Respondent means a person against whom an agency has initiated a debarment...

  12. 46 CFR 154.1000 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Applicability. 154.1000 Section 154.1000 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR... § 154.1000 Applicability. Sections 154.1005 through 154.1020 apply to flammable cargo and ammonia...

  13. 29 CFR 98.1000 - Respondent.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Respondent. 98.1000 Section 98.1000 Labor Office of the Secretary of Labor GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 98.1000 Respondent. Respondent means a person against whom an agency has initiated a debarment or suspension action. ...

  14. 7 CFR 1000.90 - Dates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Dates. 1000.90 Section 1000.90 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and... Miscellaneous Provisions § 1000.90 Dates. If a date required for a payment contained in a Federal milk order...

  15. 7 CFR 1000.90 - Dates.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Dates. 1000.90 Section 1000.90 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and... Miscellaneous Provisions § 1000.90 Dates. If a date required for a payment contained in a Federal milk order...

  16. 21 CFR 1404.1000 - Respondent.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Respondent. 1404.1000 Section 1404.1000 Food and Drugs OFFICE OF NATIONAL DRUG CONTROL POLICY GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 1404.1000 Respondent. Respondent means a person against whom an agency has initiated a debarment...

  17. 45 CFR 1000.3 - Requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Requirements. 1000.3 Section 1000.3 Public Welfare... ESTABLISHED PURSUANT TO GRANTS FOR ASSETS FOR INDEPENDENCE § 1000.3 Requirements. (a) A qualified entity... and Human Services' uniform administrative requirements under 45 CFR part 74. (b) Any reserve fund...

  18. 45 CFR 1000.3 - Requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Requirements. 1000.3 Section 1000.3 Public Welfare... ESTABLISHED PURSUANT TO GRANTS FOR ASSETS FOR INDEPENDENCE § 1000.3 Requirements. (a) A qualified entity... and Human Services' uniform administrative requirements under 45 CFR part 74. (b) Any reserve fund...

  19. 45 CFR 1000.3 - Requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Requirements. 1000.3 Section 1000.3 Public Welfare... ESTABLISHED PURSUANT TO GRANTS FOR ASSETS FOR INDEPENDENCE § 1000.3 Requirements. (a) A qualified entity... and Human Services' uniform administrative requirements under 45 CFR part 74. (b) Any reserve fund...

  20. 45 CFR 1000.3 - Requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Requirements. 1000.3 Section 1000.3 Public Welfare... ESTABLISHED PURSUANT TO GRANTS FOR ASSETS FOR INDEPENDENCE § 1000.3 Requirements. (a) A qualified entity... and Human Services' uniform administrative requirements under 45 CFR part 74. (b) Any reserve fund...

  1. 45 CFR 1000.3 - Requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Requirements. 1000.3 Section 1000.3 Public Welfare... ESTABLISHED PURSUANT TO GRANTS FOR ASSETS FOR INDEPENDENCE § 1000.3 Requirements. (a) A qualified entity... and Human Services' uniform administrative requirements under 45 CFR part 74. (b) Any reserve fund...

  2. 21 CFR 1000.1 - General.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false General. 1000.1 Section 1000.1 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) RADIOLOGICAL HEALTH GENERAL General Provisions § 1000.1 General. References in this subchapter J to regulatory sections of the...

  3. 25 CFR 1000.1 - Authority.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Authority. 1000.1 Section 1000.1 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL... § 1000.1 Authority. This part is prepared and issued by the Secretary of the Interior under the...

  4. 21 CFR 573.1000 - Verxite.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., AND RELATED PRODUCTS FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS Food Additive Listing § 573.1000 Verxite. The food additive verxite may be safely used in animal feed in accordance with... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Verxite. 573.1000 Section 573.1000 Food and Drugs...

  5. 21 CFR 573.1000 - Verxite.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., AND RELATED PRODUCTS FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS Food Additive Listing § 573.1000 Verxite. The food additive verxite may be safely used in animal feed in accordance with... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Verxite. 573.1000 Section 573.1000 Food and Drugs...

  6. 21 CFR 573.1000 - Verxite.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., AND RELATED PRODUCTS FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS Food Additive Listing § 573.1000 Verxite. The food additive verxite may be safely used in animal feed in accordance with... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Verxite. 573.1000 Section 573.1000 Food and Drugs...

  7. 21 CFR 573.1000 - Verxite.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., AND RELATED PRODUCTS FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS Food Additive Listing § 573.1000 Verxite. The food additive verxite may be safely used in animal feed in accordance with... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Verxite. 573.1000 Section 573.1000 Food and Drugs...

  8. 21 CFR 573.1000 - Verxite.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., AND RELATED PRODUCTS FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS Food Additive Listing § 573.1000 Verxite. The food additive verxite may be safely used in animal feed in accordance with... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Verxite. 573.1000 Section 573.1000 Food and Drugs...

  9. 7 CFR 1000.4 - Plant.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Plant. 1000.4 Section 1000.4 Agriculture Regulations... § 1000.4 Plant. (a) Except as provided in paragraph (b) of this section, plant means the land, buildings... section if the facility receives the milk of more than one dairy farmer. (b) Plant shall not include: (1...

  10. 7 CFR 1000.4 - Plant.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Plant. 1000.4 Section 1000.4 Agriculture Regulations of... § 1000.4 Plant. (a) Except as provided in paragraph (b) of this section, plant means the land, buildings... section if the facility receives the milk of more than one dairy farmer. (b) Plant shall not include: (1...

  11. 7 CFR 1000.4 - Plant.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Plant. 1000.4 Section 1000.4 Agriculture Regulations... § 1000.4 Plant. (a) Except as provided in paragraph (b) of this section, plant means the land, buildings... section if the facility receives the milk of more than one dairy farmer. (b) Plant shall not include: (1...

  12. 7 CFR 1000.4 - Plant.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Plant. 1000.4 Section 1000.4 Agriculture Regulations... § 1000.4 Plant. (a) Except as provided in paragraph (b) of this section, plant means the land, buildings... section if the facility receives the milk of more than one dairy farmer. (b) Plant shall not include: (1...

  13. 7 CFR 1000.4 - Plant.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Plant. 1000.4 Section 1000.4 Agriculture Regulations of... § 1000.4 Plant. (a) Except as provided in paragraph (b) of this section, plant means the land, buildings... section if the facility receives the milk of more than one dairy farmer. (b) Plant shall not include: (1...

  14. 7 CFR 1000.54 - Equivalent price.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Equivalent price. 1000.54 Section 1000.54 Agriculture... Prices § 1000.54 Equivalent price. If for any reason a price or pricing constituent required for computing the prices described in § 1000.50 is not available, the market administrator shall use a price or...

  15. 7 CFR 1000.5 - Distributing plant.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Distributing plant. 1000.5 Section 1000.5 Agriculture... Definitions § 1000.5 Distributing plant. Distributing plant means a plant that is approved by a duly... plants. ...

  16. 7 CFR 1000.5 - Distributing plant.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Distributing plant. 1000.5 Section 1000.5 Agriculture... Definitions § 1000.5 Distributing plant. Distributing plant means a plant that is approved by a duly... plants. ...

  17. 7 CFR 1000.5 - Distributing plant.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Distributing plant. 1000.5 Section 1000.5 Agriculture... Definitions § 1000.5 Distributing plant. Distributing plant means a plant that is approved by a duly... plants. ...

  18. 7 CFR 1000.5 - Distributing plant.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Distributing plant. 1000.5 Section 1000.5 Agriculture... Definitions § 1000.5 Distributing plant. Distributing plant means a plant that is approved by a duly... plants. ...

  19. 7 CFR 1000.5 - Distributing plant.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Distributing plant. 1000.5 Section 1000.5 Agriculture... Definitions § 1000.5 Distributing plant. Distributing plant means a plant that is approved by a duly... plants. ...

  20. Super cool X-1000 and Super cool Z-1000, two ice blockers, and their effect on vitrification/warming of mouse embryos.

    PubMed

    Badrzadeh, H; Najmabadi, S; Paymani, R; Macaso, T; Azadbadi, Z; Ahmady, A

    2010-07-01

    To evaluate the survival and blastocyst formation rates of mouse embryos after vitrification/thaw process with different ice blocker media. We used X-1000 and Z-1000 separately and mixed using V-Kim, a closed vitrification system. Mouse embryos were vitrified using ethylene glycol based medium supplemented with Super cool X-1000 and/or Super cool Z-1000. Survival rates for the control, Super cool X-1000, Super cool Z-1000, and Super cool X-1000/Z-1000 groups were 74%, 72%, 68%, and 85% respectively, with no significant difference among experimental and control groups; however, a significantly higher survival rate was noticed in the Super cool X-1000/Z-1000 group when compared with the Super cool Z-1000 group. Blastocyst formation rates for the control, Super cool X-1000, Super cool Z-1000, and Super cool X-1000/Z-1000 groups were 71%, 66%, 65%, and 72% respectively. There was no significant difference in this rate among control and experimental groups. In a closed vitrification system, addition of ice blocker Super cool X-1000 to the vitrification solution containing Super cool Z-1000 may improve the embryo survival rate. We recommend combined ice blocker usage to optimize the vitrification outcome. Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.

  1. 16 CFR 1000.13 - Directives System.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Directives System. 1000.13 Section 1000.13 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION ORGANIZATION AND FUNCTIONS § 1000.13 Directives System. The Commission maintains a Directives System which contains delegations of...

  2. 16 CFR 1000.13 - Directives System.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Directives System. 1000.13 Section 1000.13 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION ORGANIZATION AND FUNCTIONS § 1000.13 Directives System. The Commission maintains a Directives System which contains delegations of...

  3. 16 CFR 1000.13 - Directives System.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Directives System. 1000.13 Section 1000.13 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION ORGANIZATION AND FUNCTIONS § 1000.13 Directives System. The Commission maintains a Directives System which contains delegations of...

  4. 16 CFR 1000.4 - Commission address.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Commission address. 1000.4 Section 1000.4 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION ORGANIZATION AND FUNCTIONS § 1000..., Bethesda, Maryland 20814. All written communications with the Commission, including those sent by U.S...

  5. 7 CFR 1000.18 - Cooperative association.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Cooperative association. 1000.18 Section 1000.18... Definitions § 1000.18 Cooperative association. Cooperative association means any cooperative marketing... milk products for its members. A federation of 2 or more cooperatives incorporated under the laws of...

  6. 16 CFR 1000.2 - Laws administered.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Laws administered. 1000.2 Section 1000.2 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION ORGANIZATION AND FUNCTIONS § 1000.2 Laws administered. The Commission administers five acts: (a) The Consumer Product Safety Act (Pub...

  7. 16 CFR 1000.2 - Laws administered.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Laws administered. 1000.2 Section 1000.2 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION ORGANIZATION AND FUNCTIONS § 1000.2 Laws administered. The Commission administers five acts: (a) The Consumer Product Safety Act (Pub...

  8. 16 CFR 1000.2 - Laws administered.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Laws administered. 1000.2 Section 1000.2 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION ORGANIZATION AND FUNCTIONS § 1000.2 Laws administered. The Commission administers five acts: (a) The Consumer Product Safety Act (Pub...

  9. 16 CFR 1000.2 - Laws administered.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Laws administered. 1000.2 Section 1000.2 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION ORGANIZATION AND FUNCTIONS § 1000.2 Laws administered. The Commission administers five acts: (a) The Consumer Product Safety Act (Pub...

  10. 7 CFR 1000.25 - Market administrator.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Market administrator. 1000.25 Section 1000.25... Rules of Practice and Procedure Governing Market Administrators § 1000.25 Market administrator. (a) Designation. The agency for the administration of the order shall be a market administrator selected by the...

  11. 12 CFR 611.1000 - General authority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false General authority. 611.1000 Section 611.1000 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ORGANIZATION Bank Mergers, Consolidations and Charter Amendments § 611.1000 General authority. (a) An amendment to a bank charter may relate...

  12. 7 CFR 1000.8 - Nonpool plant.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Nonpool plant. 1000.8 Section 1000.8 Agriculture... Definitions § 1000.8 Nonpool plant. Nonpool plant means any milk receiving, manufacturing, or processing plant other than a pool plant. The following categories of nonpool plants are further defined as follows: (a...

  13. 7 CFR 1000.8 - Nonpool plant.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Nonpool plant. 1000.8 Section 1000.8 Agriculture... Definitions § 1000.8 Nonpool plant. Nonpool plant means any milk receiving, manufacturing, or processing plant other than a pool plant. The following categories of nonpool plants are further defined as follows: (a...

  14. 7 CFR 1000.6 - Supply plant.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Supply plant. 1000.6 Section 1000.6 Agriculture... Definitions § 1000.6 Supply plant. Supply plant means a plant approved by a duly constituted regulatory agency... diverts fluid milk products to other plants or manufactures dairy products on its premises. ...

  15. 7 CFR 1000.6 - Supply plant.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Supply plant. 1000.6 Section 1000.6 Agriculture... Definitions § 1000.6 Supply plant. Supply plant means a plant approved by a duly constituted regulatory agency... diverts fluid milk products to other plants or manufactures dairy products on its premises. ...

  16. 7 CFR 1000.6 - Supply plant.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Supply plant. 1000.6 Section 1000.6 Agriculture... Definitions § 1000.6 Supply plant. Supply plant means a plant approved by a duly constituted regulatory agency... diverts fluid milk products to other plants or manufactures dairy products on its premises. ...

  17. 7 CFR 1000.8 - Nonpool plant.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Nonpool plant. 1000.8 Section 1000.8 Agriculture... Definitions § 1000.8 Nonpool plant. Nonpool plant means any milk receiving, manufacturing, or processing plant other than a pool plant. The following categories of nonpool plants are further defined as follows: (a...

  18. 7 CFR 1000.6 - Supply plant.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Supply plant. 1000.6 Section 1000.6 Agriculture... Definitions § 1000.6 Supply plant. Supply plant means a plant approved by a duly constituted regulatory agency... diverts fluid milk products to other plants or manufactures dairy products on its premises. ...

  19. 7 CFR 1000.8 - Nonpool plant.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Nonpool plant. 1000.8 Section 1000.8 Agriculture... Definitions § 1000.8 Nonpool plant. Nonpool plant means any milk receiving, manufacturing, or processing plant other than a pool plant. The following categories of nonpool plants are further defined as follows: (a...

  20. 7 CFR 1000.6 - Supply plant.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Supply plant. 1000.6 Section 1000.6 Agriculture... Definitions § 1000.6 Supply plant. Supply plant means a plant approved by a duly constituted regulatory agency... diverts fluid milk products to other plants or manufactures dairy products on its premises. ...

  1. 21 CFR 589.1000 - Gentian violet.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Gentian violet. 589.1000 Section 589.1000 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... Substances Prohibited From Use in Animal Food or Feed § 589.1000 Gentian violet. The Food and Drug...

  2. 42 CFR 1000.10 - General definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 5 2013-10-01 2013-10-01 false General definitions. 1000.10 Section 1000.10 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS INTRODUCTION; GENERAL DEFINITIONS Definitions § 1000.10 General definitions. In this chapter, unless the context indicates otherwise— Act...

  3. 42 CFR 1000.10 - General definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 5 2012-10-01 2012-10-01 false General definitions. 1000.10 Section 1000.10 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS INTRODUCTION; GENERAL DEFINITIONS Definitions § 1000.10 General definitions. In this chapter, unless the context indicates otherwise— Act...

  4. 42 CFR 1000.10 - General definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 5 2011-10-01 2011-10-01 false General definitions. 1000.10 Section 1000.10 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS INTRODUCTION; GENERAL DEFINITIONS Definitions § 1000.10 General definitions. In this chapter, unless the context indicates otherwise— Act...

  5. 42 CFR 1000.10 - General definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false General definitions. 1000.10 Section 1000.10 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS INTRODUCTION; GENERAL DEFINITIONS Definitions § 1000.10 General definitions. In this chapter, unless the context indicates otherwise— Act...

  6. 42 CFR 1000.10 - General definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 5 2014-10-01 2014-10-01 false General definitions. 1000.10 Section 1000.10 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS INTRODUCTION; GENERAL DEFINITIONS Definitions § 1000.10 General definitions. In this chapter, unless the context indicates otherwise— Act...

  7. Crystal structure, magnetism, and luminescent properties of two isostructural pcu MOFs based on a triangular ligand

    NASA Astrophysics Data System (ADS)

    Yan, Pen-Ji; Yao, Xiao-Qiang; Xie, Hua; Xiao, Guo-Bin; Liu, Jia-Cheng; Xu, Xin-Jian

    2018-05-01

    Two isomorphous metal-organic frameworks, {[M(TIPA) (btec)½]H2O}n, [M = Co (1) or Zn (2)] were synthesized hydrothermally based on a semi-rigid N-center triangular ligand TIPA, where TIPA = tris(4-(1H-imidazol-1-yl)-phenyl)amine, H4btec = 1,2,4,5-benzenetetracarboxylic acid. Single crystal structural analyses show that complexes 1 and 2 are isostructural and both feature a twofold interpenetrated pcu topology. In 1 and 2, the btec4- ligand adopting μ2-η2:η1 and μ1-η1:η0 coordination modes connect adjacent dinuclear Co/Zn units to form a 1D straight polymeric chain. Then these chains arranged in parallel/parallel fashion were further extended to a 3D network by exo-tridentate ligand TIPA with μ2-κ2N:N‧ coordination mode. The magnetic property of 1 and the luminescent property of 2 were investigated. Furthermore, the structure and spectroscopic property of 2 were further investigated by DFT and TD-DFT calculations.

  8. 48 CFR 23.1000 - Scope.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Scope. 23.1000 Section 23.1000 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE...

  9. 48 CFR 23.1000 - Scope.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Scope. 23.1000 Section 23.1000 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE...

  10. 48 CFR 23.1000 - Scope.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Scope. 23.1000 Section 23.1000 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE...

  11. Tau-independent Phase Analysis: A Novel Method for Accurately Determining Phase Shifts.

    PubMed

    Tackenberg, Michael C; Jones, Jeff R; Page, Terry L; Hughey, Jacob J

    2018-06-01

    Estimations of period and phase are essential in circadian biology. While many techniques exist for estimating period, comparatively few methods are available for estimating phase. Current approaches to analyzing phase often vary between studies and are sensitive to coincident changes in period and the stage of the circadian cycle at which the stimulus occurs. Here we propose a new technique, tau-independent phase analysis (TIPA), for quantifying phase shifts in multiple types of circadian time-course data. Through comprehensive simulations, we show that TIPA is both more accurate and more precise than the standard actogram approach. TIPA is computationally simple and therefore will enable accurate and reproducible quantification of phase shifts across multiple subfields of chronobiology.

  12. 48 CFR 23.1000 - Scope.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Scope. 23.1000 Section 23.1000 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS... environmental management system (EMS) at a Federal facility; and (c) Completion of facility compliance audits...

  13. 46 CFR 154.1000 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Applicability. 154.1000 Section 154.1000 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Electrical...

  14. 46 CFR 154.1000 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Applicability. 154.1000 Section 154.1000 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Electrical...

  15. 46 CFR 154.1000 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Applicability. 154.1000 Section 154.1000 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Electrical...

  16. 46 CFR 154.1000 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Applicability. 154.1000 Section 154.1000 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Electrical...

  17. 33 CFR 151.1000 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Purpose. 151.1000 Section 151.1000 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION VESSELS CARRYING OIL, NOXIOUS LIQUID SUBSTANCES, GARBAGE, MUNICIPAL OR COMMERCIAL WASTE, AND BALLAST WATER...

  18. 33 CFR 151.1000 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Purpose. 151.1000 Section 151.1000 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION VESSELS CARRYING OIL, NOXIOUS LIQUID SUBSTANCES, GARBAGE, MUNICIPAL OR COMMERCIAL WASTE, AND BALLAST WATER...

  19. 33 CFR 151.1000 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Purpose. 151.1000 Section 151.1000 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION VESSELS CARRYING OIL, NOXIOUS LIQUID SUBSTANCES, GARBAGE, MUNICIPAL OR COMMERCIAL WASTE, AND BALLAST WATER...

  20. 33 CFR 151.1000 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Purpose. 151.1000 Section 151.1000 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION VESSELS CARRYING OIL, NOXIOUS LIQUID SUBSTANCES, GARBAGE, MUNICIPAL OR COMMERCIAL WASTE, AND BALLAST WATER...

  1. 33 CFR 151.1000 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Purpose. 151.1000 Section 151.1000 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION VESSELS CARRYING OIL, NOXIOUS LIQUID SUBSTANCES, GARBAGE, MUNICIPAL OR COMMERCIAL WASTE, AND BALLAST WATER...

  2. Generation of live offspring from vitrified embryos with synthetic polymers SuperCool X-1000 and SuperCool Z-1000.

    PubMed

    Marco-Jimenez, F; Jimenez-Trigos, E; Lavara, R; Vicente, J S

    2014-01-01

    Ice growth and recrystallisation are considered important factors in determining vitrification outcomes. Synthetic polymers inhibit ice formation during cooling or warming of the vitrification process. The aim of this study was to assess the effect of adding commercially available synthetic polymers SuperCool X-1000 and SuperCool Z-1000 to vitrification media on in vivo development competence of rabbit embryos. Four hundred and thirty morphologically normal embryos recovered at 72 h of gestation were used. The vitrification media contained 20% dimethyl sulphoxide and 20% ethylene glycol, either alone or in combination with 1% of SuperCool X-1000 and 1% SuperCool. Our results show that embryos can be successfully vitrified using SuperCool X-1000 and SuperCool Z-1000 and when embryos are transferred, live offspring can be successfully produced. In conclusion, our results demonstrated that we succeeded for the first time in obtaining live offspring after vitrification of embryos using SuperCool X-1000 and SuperCool Z-1000 polymers.

  3. 16 CFR 1000.5 - Petitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Petitions. 1000.5 Section 1000.5 Commercial... Petitions. Any interested person may petition the Commission to issue, amend, or revoke a rule or regulation... Highway, Bethesda, Maryland 20814. Petitions must comply with the Commission's procedure for petitioning...

  4. 7 CFR 1940.1000 - OMB control number.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 13 2010-01-01 2009-01-01 true OMB control number. 1940.1000 Section 1940.1000 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS....1000 OMB control number. The collection of information requirements contained in this regulation has...

  5. 16 CFR § 1000.13 - Directives System.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Directives System. § 1000.13 Section § 1000.13 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION ORGANIZATION AND FUNCTIONS § 1000.13 Directives System. The Commission maintains a Directives System which contains...

  6. 7 CFR 4284.1000 - OMB control number.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false OMB control number. 4284.1000 Section 4284.1000 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GRANTS Value-Added Producer Grants § 4284.1000 OMB...

  7. 26 CFR 1.998-1.1000 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 10 2010-04-01 2010-04-01 false [Reserved] 1.998-1.1000 Section 1.998-1.1000 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Domestic International Sales Corporations §§ 1.998-1.1000 [Reserved] ...

  8. 40 CFR 272.1000-272.1049 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 28 2012-07-01 2012-07-01 false [Reserved] 272.1000-272.1049 Section 272.1000-272.1049 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Maine §§ 272.1000-272.1049 [Reserved] ...

  9. 40 CFR 272.1000-272.1049 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 27 2011-07-01 2011-07-01 false [Reserved] 272.1000-272.1049 Section 272.1000-272.1049 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Maine §§ 272.1000-272.1049 [Reserved] ...

  10. 40 CFR 272.1000-272.1049 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 27 2014-07-01 2014-07-01 false [Reserved] 272.1000-272.1049 Section 272.1000-272.1049 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Maine §§ 272.1000-272.1049 [Reserved] ...

  11. 40 CFR 272.1000-272.1049 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 28 2013-07-01 2013-07-01 false [Reserved] 272.1000-272.1049 Section 272.1000-272.1049 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Maine §§ 272.1000-272.1049 [Reserved] ...

  12. 40 CFR 272.1000-272.1049 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false [Reserved] 272.1000-272.1049 Section 272.1000-272.1049 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Maine §§ 272.1000-272.1049 [Reserved] ...

  13. 16 CFR § 1000.2 - Laws administered.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Laws administered. § 1000.2 Section § 1000.2 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION ORGANIZATION AND FUNCTIONS § 1000.2 Laws administered. The Commission administers five acts: (a) The Consumer Product Safety...

  14. 7 CFR 1940.1000 - OMB control number.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 13 2014-01-01 2013-01-01 true OMB control number. 1940.1000 Section 1940.1000....1000 OMB control number. The collection of information requirements contained in this regulation has been approved by the Office of Management and Budget and assigned OMB control number 0575-0145. Public...

  15. 7 CFR 1940.1000 - OMB control number.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 13 2013-01-01 2013-01-01 false OMB control number. 1940.1000 Section 1940.1000....1000 OMB control number. The collection of information requirements contained in this regulation has been approved by the Office of Management and Budget and assigned OMB control number 0575-0145. Public...

  16. 7 CFR 1000.15 - Fluid milk product.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Fluid milk product. 1000.15 Section 1000.15 Agriculture... and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Definitions § 1000.15 Fluid milk product. (a) Except as provided in paragraph (b) of this section, fluid milk...

  17. 7 CFR 1000.14 - Other source milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Other source milk. 1000.14 Section 1000.14 Agriculture... and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Definitions § 1000.14 Other source milk. Other source milk means all skim milk and butterfat contained in or...

  18. 7 CFR 1000.14 - Other source milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Other source milk. 1000.14 Section 1000.14 Agriculture... and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Definitions § 1000.14 Other source milk. Other source milk means all skim milk and butterfat contained in or...

  19. 7 CFR 1000.15 - Fluid milk product.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Fluid milk product. 1000.15 Section 1000.15... Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Definitions § 1000.15 Fluid milk product. (a) Except as provided in paragraph (b) of this section, fluid milk...

  20. 10 CFR 1000.1 - Transfer of proceedings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Transfer of proceedings. 1000.1 Section 1000.1 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) TRANSFER OF PROCEEDINGS TO THE SECRETARY OF ENERGY AND THE FEDERAL ENERGY REGULATORY COMMISSION § 1000.1 Transfer of proceedings. (a) Scope. This part establishes the...

  1. 7 CFR 1000.14 - Other source milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Other source milk. 1000.14 Section 1000.14 Agriculture... and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Definitions § 1000.14 Other source milk. Other source milk means all skim milk and butterfat contained in or...

  2. 7 CFR 1000.14 - Other source milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Other source milk. 1000.14 Section 1000.14 Agriculture... AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Definitions § 1000.14 Other source milk. Other source milk means all skim milk and butterfat contained in or...

  3. 7 CFR 1000.14 - Other source milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Other source milk. 1000.14 Section 1000.14 Agriculture... AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Definitions § 1000.14 Other source milk. Other source milk means all skim milk and butterfat contained in or...

  4. 25 CFR 39.1000 - Purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Purpose and scope. 39.1000 Section 39.1000 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION THE INDIAN SCHOOL EQUALIZATION PROGRAM Administrative Cost Formula § 39.1000 Purpose and scope. The purpose of this subpart is to provide funds at the...

  5. 27 CFR 19.1000 - Reconsignment in transit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Reconsignment in transit. 19.1000 Section 19.1000 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Distilled Spirits For Fuel Use Uses, Withdrawals and Transfers § 19.1000...

  6. 16 CFR 1000.12 - Organizational structure.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Organizational structure. 1000.12 Section... FUNCTIONS § 1000.12 Organizational structure. The Consumer Product Safety Commission is composed of the...) Directorate for Epidemiology; (3) Directorate for Health Sciences; (4) Directorate for Engineering Sciences...

  7. 16 CFR 1000.12 - Organizational structure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Organizational structure. 1000.12 Section... FUNCTIONS § 1000.12 Organizational structure. The Consumer Product Safety Commission is composed of the...) Directorate for Epidemiology; (3) Directorate for Health Sciences; (4) Directorate for Engineering Sciences...

  8. 30 CFR 75.1000 - Cutout switches.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Cutout switches. 75.1000 Section 75.1000... switches. [Statutory Provisions] Trolley wires and trolley feeder wires, shall be provided with cutout switches at intervals of not more than 2,000 feet and near the beginning of all branch lines. ...

  9. 30 CFR 75.1000 - Cutout switches.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Cutout switches. 75.1000 Section 75.1000... switches. [Statutory Provisions] Trolley wires and trolley feeder wires, shall be provided with cutout switches at intervals of not more than 2,000 feet and near the beginning of all branch lines. ...

  10. 30 CFR 75.1000 - Cutout switches.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Cutout switches. 75.1000 Section 75.1000... switches. [Statutory Provisions] Trolley wires and trolley feeder wires, shall be provided with cutout switches at intervals of not more than 2,000 feet and near the beginning of all branch lines. ...

  11. 16 CFR 1000.15 - Office of Congressional Relations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Office of Congressional Relations. 1000.15 Section 1000.15 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION ORGANIZATION AND FUNCTIONS § 1000.15 Office of Congressional Relations. The Office of Congressional Relations is...

  12. 24 CFR 1000.101 - What is affordable housing?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What is affordable housing? 1000.101 Section 1000.101 Housing and Urban Development Regulations Relating to Housing and Urban... URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES Affordable Housing Activities § 1000.101 What is...

  13. 7 CFR 1000.44 - Classification of producer milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Classification of producer milk. 1000.44 Section 1000... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.44 Classification of producer milk. For each month...

  14. 7 CFR 1000.44 - Classification of producer milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Classification of producer milk. 1000.44 Section 1000... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.44 Classification of producer milk. For each month...

  15. 13 CFR 120.1000 - Risk-Based Lender Oversight.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Risk-Based Lender Oversight. 120.1000 Section 120.1000 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Risk-Based Lender Oversight Supervision § 120.1000 Risk-Based Lender Oversight. (a) Risk-Based Lender...

  16. 7 CFR 1000.44 - Classification of producer milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Classification of producer milk. 1000.44 Section 1000... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.44 Classification of producer milk. For each month...

  17. 7 CFR 1000.44 - Classification of producer milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Classification of producer milk. 1000.44 Section 1000... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.44 Classification of producer milk. For each month...

  18. 7 CFR 1000.44 - Classification of producer milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Classification of producer milk. 1000.44 Section 1000... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.44 Classification of producer milk. For each month...

  19. Applications of the 1000 Genomes Project resources

    PubMed Central

    Zheng-Bradley, Xiangqun

    2017-01-01

    Abstract The 1000 Genomes Project created a valuable, worldwide reference for human genetic variation. Common uses of the 1000 Genomes dataset include genotype imputation supporting Genome-wide Association Studies, mapping expression Quantitative Trait Loci, filtering non-pathogenic variants from exome, whole genome and cancer genome sequencing projects, and genetic analysis of population structure and molecular evolution. In this article, we will highlight some of the multiple ways that the 1000 Genomes data can be and has been utilized for genetic studies. PMID:27436001

  20. Moisture content calculations for 1000-hour timelag fuels

    Treesearch

    Michael A. Fosberg; Richard C. Rothermel; Patricia L. Andrews

    1981-01-01

    Techniques to calculate 1000-hour timelag fuel moistures were developed from theory of water movement in wood. The 1000-hour timelag fuel moisture is computed from mean daily temperatures and humidities and precipitation duration. Comparison of calculated and observed fuel moistures showed good agreement. Techniques to determine the seasonal starting value of the 1000-...

  1. Applications of the 1000 Genomes Project resources.

    PubMed

    Zheng-Bradley, Xiangqun; Flicek, Paul

    2017-05-01

    The 1000 Genomes Project created a valuable, worldwide reference for human genetic variation. Common uses of the 1000 Genomes dataset include genotype imputation supporting Genome-wide Association Studies, mapping expression Quantitative Trait Loci, filtering non-pathogenic variants from exome, whole genome and cancer genome sequencing projects, and genetic analysis of population structure and molecular evolution. In this article, we will highlight some of the multiple ways that the 1000 Genomes data can be and has been utilized for genetic studies. © The Author 2016. Published by Oxford University Press.

  2. 77 FR 64379 - Proposed Collection; Comment Request for Form 1000

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... 1000 AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and request for comments. SUMMARY... 1000, Ownership Certificate. DATES: Written comments should be received on or before December 18, 2012...: Ownership Certificate. OMB Number: 1545-0054. Form Number: 1000. Abstract: Form 1000 is used by citizens...

  3. 14 CFR 1204.1000 - Scope of subpart.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Scope of subpart. 1204.1000 Section 1204.1000 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION ADMINISTRATIVE AUTHORITY AND POLICY Inspection of Persons and Personal Effects at NASA Installations or on NASA Property; Trespass or...

  4. 14 CFR 1204.1000 - Scope of subpart.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Scope of subpart. 1204.1000 Section 1204.1000 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION ADMINISTRATIVE AUTHORITY AND POLICY Inspection of Persons and Personal Effects at NASA Installations or on NASA Property; Trespass or...

  5. 24 CFR 1000.12 - What nondiscrimination requirements are applicable?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What nondiscrimination requirements are applicable? 1000.12 Section 1000.12 Housing and Urban Development Regulations Relating to Housing..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.12 What...

  6. 24 CFR 1000.18 - What environmental review requirements apply?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What environmental review requirements apply? 1000.18 Section 1000.18 Housing and Urban Development Regulations Relating to Housing and... HOUSING AND URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.18 What environmental...

  7. 40 CFR 60.1000 - What does this subpart do?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What does this subpart do? 60.1000 Section 60.1000 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... Modification or Reconstruction is Commenced After June 6, 2001 Introduction § 60.1000 What does this subpart do...

  8. 16 CFR 1000.11 - Delegation of functions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Delegation of functions. 1000.11 Section... FUNCTIONS § 1000.11 Delegation of functions. Section 27(b)(9) of the Consumer Product Safety Act (15 U.S.C... to issue subpoenas, to any officer or employee of the Commission. Delegations are documented in the...

  9. 12 CFR 7.1000 - National bank ownership of property.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 1 2011-01-01 2011-01-01 false National bank ownership of property. 7.1000 Section 7.1000 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY BANK ACTIVITIES AND OPERATIONS Bank Powers § 7.1000 National bank ownership of property. (a) Investment in real estate...

  10. 25 CFR 1000.354 - What is a trust evaluation?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... that the functions are performed in accordance with trust standards as defined by Federal law. Trust... 25 Indians 2 2010-04-01 2010-04-01 false What is a trust evaluation? 1000.354 Section 1000.354... Trust Evaluation Review Annual Trust Evaluations § 1000.354 What is a trust evaluation? A trust...

  11. 24 CFR 1000.28 - May a self-governance Indian tribe be exempted from the applicability of § 1000.26?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false May a self-governance Indian tribe... ACTIVITIES General § 1000.28 May a self-governance Indian tribe be exempted from the applicability of § 1000.26? Yes. A self-governance Indian tribe shall certify that its administrative requirements, standards...

  12. 15 CFR 971.1000 - General.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS Enforcement § 971.1000 General. (a...

  13. 15 CFR 971.1000 - General.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS Enforcement § 971.1000 General. (a...

  14. 15 CFR 971.1000 - General.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS Enforcement § 971.1000 General. (a...

  15. 15 CFR 971.1000 - General.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS Enforcement § 971.1000 General. (a...

  16. 15 CFR 971.1000 - General.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS Enforcement § 971.1000 General. (a...

  17. 7 CFR 1000.85 - Assessment for order administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1000.85 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Administrative Assessment and Marketing Service Deduction § 1000.85 Assessment...

  18. 45 CFR 155.1000 - Certification standards for QHPs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 155.1000 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS EXCHANGE ESTABLISHMENT STANDARDS AND OTHER RELATED STANDARDS UNDER THE AFFORDABLE CARE ACT Exchange Functions: Certification of Qualified Health Plans § 155.1000 Certification standards for QHPs. (a...

  19. 7 CFR 1000.86 - Deduction for marketing services.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Deduction for marketing services. 1000.86 Section 1000.86 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL...

  20. 7 CFR 1000.86 - Deduction for marketing services.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Deduction for marketing services. 1000.86 Section 1000.86 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL...

  1. 7 CFR 1000.86 - Deduction for marketing services.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Deduction for marketing services. 1000.86 Section 1000.86 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL...

  2. 7 CFR 1000.86 - Deduction for marketing services.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Deduction for marketing services. 1000.86 Section 1000.86 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL...

  3. 7 CFR 1000.86 - Deduction for marketing services.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Deduction for marketing services. 1000.86 Section 1000.86 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL...

  4. 7 CFR 1000.19 - Commercial food processing establishment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Commercial food processing establishment. 1000.19... FEDERAL MILK MARKETING ORDERS Definitions § 1000.19 Commercial food processing establishment. Commercial food processing establishment means any facility, other than a milk plant, to which fluid milk products...

  5. 7 CFR 1000.19 - Commercial food processing establishment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Commercial food processing establishment. 1000.19... FEDERAL MILK MARKETING ORDERS Definitions § 1000.19 Commercial food processing establishment. Commercial food processing establishment means any facility, other than a milk plant, to which fluid milk products...

  6. 7 CFR 1000.19 - Commercial food processing establishment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Commercial food processing establishment. 1000.19... FEDERAL MILK MARKETING ORDERS Definitions § 1000.19 Commercial food processing establishment. Commercial food processing establishment means any facility, other than a milk plant, to which fluid milk products...

  7. 7 CFR 1000.19 - Commercial food processing establishment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Commercial food processing establishment. 1000.19... FEDERAL MILK MARKETING ORDERS Definitions § 1000.19 Commercial food processing establishment. Commercial food processing establishment means any facility, other than a milk plant, to which fluid milk products...

  8. 7 CFR 1000.19 - Commercial food processing establishment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Commercial food processing establishment. 1000.19... FEDERAL MILK MARKETING ORDERS Definitions § 1000.19 Commercial food processing establishment. Commercial food processing establishment means any facility, other than a milk plant, to which fluid milk products...

  9. 16 CFR 1000.29 - Directorate for Engineering Sciences.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Directorate for Engineering Sciences. 1000... ORGANIZATION AND FUNCTIONS § 1000.29 Directorate for Engineering Sciences. The Directorate for Engineering Sciences, which is managed by the Associate Executive Director for Engineering Sciences, is responsible for...

  10. 16 CFR 1000.29 - Directorate for Engineering Sciences.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Directorate for Engineering Sciences. 1000... ORGANIZATION AND FUNCTIONS § 1000.29 Directorate for Engineering Sciences. The Directorate for Engineering Sciences, which is managed by the Associate Executive Director for Engineering Sciences, is responsible for...

  11. 16 CFR 1000.30 - Directorate for Laboratory Sciences.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Directorate for Laboratory Sciences. 1000.30... AND FUNCTIONS § 1000.30 Directorate for Laboratory Sciences. The Directorate for Laboratory Sciences, which is managed by the Associate Executive Director for Laboratory Sciences, is responsible for...

  12. 16 CFR 1000.30 - Directorate for Laboratory Sciences.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Directorate for Laboratory Sciences. 1000.30... AND FUNCTIONS § 1000.30 Directorate for Laboratory Sciences. The Directorate for Laboratory Sciences, which is managed by the Associate Executive Director for Laboratory Sciences, is responsible for...

  13. 16 CFR 1000.30 - Directorate for Laboratory Sciences.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Directorate for Laboratory Sciences. 1000.30... AND FUNCTIONS § 1000.30 Directorate for Laboratory Sciences. The Directorate for Laboratory Sciences, which is managed by the Associate Executive Director for Laboratory Sciences, is responsible for...

  14. 16 CFR 1000.30 - Directorate for Laboratory Sciences.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Directorate for Laboratory Sciences. 1000.30... AND FUNCTIONS § 1000.30 Directorate for Laboratory Sciences. The Directorate for Laboratory Sciences, which is managed by the Associate Executive Director for Laboratory Sciences, is responsible for...

  15. 24 CFR 1000.102 - What are eligible affordable housing activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What are eligible affordable housing activities? 1000.102 Section 1000.102 Housing and Urban Development Regulations Relating to... § 1000.102 What are eligible affordable housing activities? Eligible affordable housing activities are...

  16. 16 CFR 1000.28 - Directorate for Economic Analysis.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Directorate for Economic Analysis. 1000.28... AND FUNCTIONS § 1000.28 Directorate for Economic Analysis. The Directorate for Economic Analysis, which is managed by the Associate Executive Director for Economic Analysis, is responsible for providing...

  17. 16 CFR 1000.27 - Directorate for Health Sciences.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Directorate for Health Sciences. 1000.27... AND FUNCTIONS § 1000.27 Directorate for Health Sciences. The Directorate for Health Sciences is managed by the Associate Executive Director for Health Sciences and is responsible for reviewing and...

  18. 16 CFR 1000.27 - Directorate for Health Sciences.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Directorate for Health Sciences. 1000.27... AND FUNCTIONS § 1000.27 Directorate for Health Sciences. The Directorate for Health Sciences is managed by the Associate Executive Director for Health Sciences and is responsible for reviewing and...

  19. 16 CFR 1000.27 - Directorate for Health Sciences.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Directorate for Health Sciences. 1000.27... AND FUNCTIONS § 1000.27 Directorate for Health Sciences. The Directorate for Health Sciences is managed by the Associate Executive Director for Health Sciences and is responsible for reviewing and...

  20. 16 CFR 1000.27 - Directorate for Health Sciences.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Directorate for Health Sciences. 1000.27... AND FUNCTIONS § 1000.27 Directorate for Health Sciences. The Directorate for Health Sciences is managed by the Associate Executive Director for Health Sciences and is responsible for reviewing and...

  1. 16 CFR 1000.28 - Directorate for Economic Analysis.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Directorate for Economic Analysis. 1000.28... AND FUNCTIONS § 1000.28 Directorate for Economic Analysis. The Directorate for Economic Analysis, which is managed by the Associate Executive Director for Economic Analysis, is responsible for providing...

  2. 16 CFR 1000.28 - Directorate for Economic Analysis.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Directorate for Economic Analysis. 1000.28... AND FUNCTIONS § 1000.28 Directorate for Economic Analysis. The Directorate for Economic Analysis, which is managed by the Associate Executive Director for Economic Analysis, is responsible for providing...

  3. 16 CFR 1000.28 - Directorate for Economic Analysis.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Directorate for Economic Analysis. 1000.28... AND FUNCTIONS § 1000.28 Directorate for Economic Analysis. The Directorate for Economic Analysis, which is managed by the Associate Executive Director for Economic Analysis, is responsible for providing...

  4. 16 CFR 1000.18 - Office of Executive Director.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Office of Executive Director. 1000.18... AND FUNCTIONS § 1000.18 Office of Executive Director. The Executive Director with the assistance of... offices: the Office of Financial Management, Planning and Evaluation, the Office of Hazard Identification...

  5. Modernization of existing VVER-1000 surveillance programs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kochkin, V.; Erak, D.; Makhotin, D.

    2011-07-01

    According to generally accepted world practice, evaluation of the reactor pressure vessel (RPV) material behavior during operation is carried out using tests of surveillance specimens. The main objective of the surveillance program consists in insurance of safe RPV operation during the design lifetime and lifetime-extension period. At present, the approaches of pressure vessels residual life validation based on the test results of their surveillance specimens have been developed and introduced in Russia and are under consideration in other countries where vodo-vodyanoi energetichesky reactors- (VVER-) 1000 are in operation. In this case, it is necessary to ensure leading irradiation of surveillancemore » specimens (as compared to the pressure vessel wall) and to provide uniformly irradiated specimen groups for mechanical testing. Standard surveillance program of VVER-1000 has several significant shortcomings and does not meet these requirements. Taking into account program of lifetime extension of VVER-1000 operating in Russia, it is necessary to carry out upgrading of the VVER-1000 surveillance program. This paper studies the conditions of a surveillance specimen's irradiation and upgrading of existing sets to provide monitoring and prognosis of RPV material properties for extension of the reactor's lifetime up to 60 years or more. (authors)« less

  6. 16 CFR 1000.18 - Office of Executive Director.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Office of Executive Director. 1000.18... AND FUNCTIONS § 1000.18 Office of Executive Director. The Executive Director with the assistance of... Commission policy, acts as the chief operating manager of the agency, supporting the development of the...

  7. 16 CFR 1000.18 - Office of Executive Director.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Office of Executive Director. 1000.18... AND FUNCTIONS § 1000.18 Office of Executive Director. The Executive Director with the assistance of... Commission policy, acts as the chief operating manager of the agency, supporting the development of the...

  8. 16 CFR 1000.18 - Office of Executive Director.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Office of Executive Director. 1000.18... AND FUNCTIONS § 1000.18 Office of Executive Director. The Executive Director with the assistance of... Commission policy, acts as the chief operating manager of the agency, supporting the development of the...

  9. 24 CFR 1000.314 - What is formula current assisted stock?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... recipient and are under management as indicated in the Formula Response Form. Formula current assisted stock... stock? 1000.314 Section 1000.314 Housing and Urban Development Regulations Relating to Housing and Urban... current assisted stock? Formula current assisted stock is current assisted stock as described in § 1000...

  10. 24 CFR 1000.46 - Do drug-free workplace requirements apply?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Do drug-free workplace requirements apply? 1000.46 Section 1000.46 Housing and Urban Development Regulations Relating to Housing and Urban... URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.46 Do drug-free workplace...

  11. 25 CFR 1000.393 - How does the Privacy Act apply?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false How does the Privacy Act apply? 1000.393 Section 1000.393... Miscellaneous Provisions § 1000.393 How does the Privacy Act apply? At the option of the Tribe/Consortium... considered Federal records for the purposes of the Privacy Act. ...

  12. 25 CFR 1000.393 - How does the Privacy Act apply?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false How does the Privacy Act apply? 1000.393 Section 1000.393... Miscellaneous Provisions § 1000.393 How does the Privacy Act apply? At the option of the Tribe/Consortium... considered Federal records for the purposes of the Privacy Act. ...

  13. 25 CFR 1000.393 - How does the Privacy Act apply?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false How does the Privacy Act apply? 1000.393 Section 1000.393... Miscellaneous Provisions § 1000.393 How does the Privacy Act apply? At the option of the Tribe/Consortium... considered Federal records for the purposes of the Privacy Act. ...

  14. 42 CFR 1000.30 - Definitions specific to Medicaid.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 5 2014-10-01 2014-10-01 false Definitions specific to Medicaid. 1000.30 Section 1000.30 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Government's share of a State's expenditures under the Medicaid program. FMAP stands for the Federal medical...

  15. 42 CFR 1000.30 - Definitions specific to Medicaid.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 5 2013-10-01 2013-10-01 false Definitions specific to Medicaid. 1000.30 Section 1000.30 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Government's share of a State's expenditures under the Medicaid program. FMAP stands for the Federal medical...

  16. 42 CFR 1000.30 - Definitions specific to Medicaid.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 5 2012-10-01 2012-10-01 false Definitions specific to Medicaid. 1000.30 Section 1000.30 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Government's share of a State's expenditures under the Medicaid program. FMAP stands for the Federal medical...

  17. 42 CFR 1000.30 - Definitions specific to Medicaid.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Definitions specific to Medicaid. 1000.30 Section 1000.30 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Government's share of a State's expenditures under the Medicaid program. FMAP stands for the Federal medical...

  18. 42 CFR 1000.30 - Definitions specific to Medicaid.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 5 2011-10-01 2011-10-01 false Definitions specific to Medicaid. 1000.30 Section 1000.30 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Government's share of a State's expenditures under the Medicaid program. FMAP stands for the Federal medical...

  19. 25 CFR 1000.13 - What is a “nonsignatory Tribe”?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Selection of Additional Tribes for Participation in Tribal Self-Governance Purpose and Definitions § 1000.13... participate in self-governance on its behalf. (2) Meets the eligibility criteria in § 1000.16 but chooses to...) May only become a “signatory Tribe” if it independently meets the eligibility criteria in § 1000.16...

  20. 25 CFR 1000.161 - What is a self-governance compact?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What is a self-governance compact? 1000.161 Section 1000... EDUCATION ACT Negotiation Process for Annual Funding Agreements Negotiating A Self-Governance Compact § 1000.161 What is a self-governance compact? A self-governance compact is an executed document that affirms...

  1. GW-1000. GW Pharmaceuticals.

    PubMed

    Smith, Paul F

    2004-07-01

    GW Pharmaceuticals is developing GW-1000 (Sativex), a narrow ratio delta9-tetrahydrocannabinol:cannabidiol product for the potential treatment of multiple sclerosis, spinal cord injury, neurogenic pain and peripheral neuropathy. In March 2003, the company filed for approval for the treatment of MS with the UK Medicines Control Agency, and in May 2004, filed for new drug submission with Health Canada.

  2. 48 CFR 23.1000 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Federal Compliance With Right-To-Know Laws and Pollution Prevention Requirements 23.1000 Scope...) Compliance with right-to-know laws and pollution prevention requirements; (b) Implementation of an...

  3. 24 CFR 1000.104 - What families are eligible for affordable housing activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... affordable housing activities? 1000.104 Section 1000.104 Housing and Urban Development Regulations Relating... Activities § 1000.104 What families are eligible for affordable housing activities? The following families... Indian area. (b) A non-low income Indian family may receive housing assistance in accordance with § 1000...

  4. Epidermal-skin-test 1,000 (EST-1,000)--a new reconstructed epidermis for in vitro skin corrosivity testing.

    PubMed

    Hoffmann, J; Heisler, E; Karpinski, S; Losse, J; Thomas, D; Siefken, W; Ahr, H-J; Vohr, H-W; Fuchs, H W

    2005-10-01

    The determination of a possible corrosive or irritative potential of certain products and ingredients is necessary for their classification and labeling requirements. Reconstructed skin as a model system provides fundamental advantages to single cell culture testing and leads to promising results as shown by different validation studies (for review: Fentem, J.H., Botham, P.A., 2002. ECVAM's activities in validating alternative tests for skin corrosion and irritation. ATLA 30(Suppl. 2), 61-67). In this study we introduce our new reconstructed epidermis "Epidermal-Skin-Test" (EST-1,000). This fully grown epidermis consists of proliferating as well as differentiating keratinocytes. EST-1,000 shows a high comparability to normal human skin as shown by histological and immunohistochemical data. Characteristic markers (KI-67, CK 1/10/5/14, transglutaminase, collagen IV, involucrin, beta 1 integrin) can be identified easily. The main focus of this work was to characterize EST-1,000 especially with respect to its barrier function by testing several substances of known corrosive potential. Skin corrosion was detected by the cytotoxic effect of the substances on a reconstructed epidermis after short-term application to the stratum corneum. The effect was determined by standard MTT assay and accompanying histological analysis. Hence EST-1,000 shows a very high predictive potential and closes the gap between animal testing and the established full-thickness model Advanced-Skin-Test 2,000 (AST-2,000) (Noll, M., Merkle, M.-L., Kandsberger, M., Matthes, T., Fuchs, H., Graeve, T., 1999. Reconstructed human skin (AST-2,000) as a tool for pharmaco-toxicology. ATLA 27, 302).

  5. 47 CFR 76.1000 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CABLE TELEVISION SERVICE Competitive Access to Cable Programming § 76.1000 Definitions. As used in this..., satellite cable programming vendors, satellite broadcast programming vendors, or terrestrial cable programming vendors will be attributed to their holders and may subject the interest holders to the rules of...

  6. 47 CFR 76.1000 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... CABLE TELEVISION SERVICE Competitive Access to Cable Programming § 76.1000 Definitions. As used in this..., satellite cable programming vendors, satellite broadcast programming vendors, or terrestrial cable programming vendors will be attributed to their holders and may subject the interest holders to the rules of...

  7. 47 CFR 76.1000 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CABLE TELEVISION SERVICE Competitive Access to Cable Programming § 76.1000 Definitions. As used in this..., satellite cable programming vendors, satellite broadcast programming vendors, or terrestrial cable programming vendors will be attributed to their holders and may subject the interest holders to the rules of...

  8. 47 CFR 76.1000 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CABLE TELEVISION SERVICE Competitive Access to Cable Programming § 76.1000 Definitions. As used in this..., satellite cable programming vendors, satellite broadcast programming vendors, or terrestrial cable programming vendors will be attributed to their holders and may subject the interest holders to the rules of...

  9. 47 CFR 76.1000 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CABLE TELEVISION SERVICE Competitive Access to Cable Programming § 76.1000 Definitions. As used in this..., satellite cable programming vendors, satellite broadcast programming vendors, or terrestrial cable programming vendors will be attributed to their holders and may subject the interest holders to the rules of...

  10. 10 CFR 603.1000 - Contracting officer's responsibilities at time of award.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Contracting officer's responsibilities at time of award. 603.1000 Section 603.1000 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Executing the Award § 603.1000 Contracting officer's responsibilities at time of award...

  11. 13 CFR 107.1000 - Licensees without Leverage-exceptions to the regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Licensees without Leverage-exceptions to the regulations. 107.1000 Section 107.1000 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS INVESTMENT COMPANIES Non-leveraged Licensees-Exceptions to Regulations § 107.1000...

  12. Global atmospheric circulation statistics, 1000-1 mb

    NASA Technical Reports Server (NTRS)

    Randel, William J.

    1992-01-01

    The atlas presents atmospheric general circulation statistics derived from twelve years (1979-90) of daily National Meteorological Center (NMC) operational geopotential height analyses; it is an update of a prior atlas using data over 1979-1986. These global analyses are available on pressure levels covering 1000-1 mb (approximately 0-50 km). The geopotential grids are a combined product of the Climate Analysis Center (which produces analyses over 70-1 mb) and operational NMC analyses (over 1000-100 mb). Balance horizontal winds and hydrostatic temperatures are derived from the geopotential fields.

  13. Evaluating the Adsoptive Capacities of Chemsorb 1000 and Chemsorb 1425

    NASA Technical Reports Server (NTRS)

    Monje, Oscar Alberto; Surma, Jan M.; Johnsey, Marissa N.; Melendez, Orlando

    2014-01-01

    The Air Revitalization Lab at KSC tested Chemsorb 1000 and 1425, two candidate sorbents for use in future air revitalization technologies being evaluated by the ARREM project. Chemsorb 1000 and 1425 are granular coconut-shell activated carbon sorbents produced by Molecular Products, Inc. that may be used in the TCCS. Chemsorb 1000 is a high grade activated carbon for organic vapor adsorption. In contrast, Chemsorb 1425 is a high-grade impregnated activated carbon for adsorption of airborne ammonia and amines. Chemsorb 1000 was challenged with simulated spacecraft gas streams in order to determine its adsorptive capacities for mixtures of volatile organics compounds. Chemsorb 1425 was challenged with various NH3 concentrations to determine its adsorptive capacity.

  14. Evaluating the Adsorptive Capacities of Chemsorb 1000 and Chemsorb 1425

    NASA Technical Reports Server (NTRS)

    Monje, Oscar Alberto Monje; Surma, Jan M.; Johnsey, Marissa N.; Melendez, Orlando

    2014-01-01

    The Air Revitalization Lab at KSC tested Chemsorb 1000 and 1425, two candidate sorbents for use in future air revitalization technologies being evaluated by the ARREM project. Chemsorb 1000 and 1425 are granular coconut-shell activated carbon sorbents produced by Molecular Products, Inc. that may be used in the TCCS. Chemsorb 1000 is a high grade activated carbon for organic vapor adsorption. In contrast, Chemsorb 1425 is a high-grade impregnated activated carbon for adsorption of airborne ammonia and amines. Chemsorb 1000 was challenged with simulated spacecraft gas streams in order to determine its adsorptive capacities for mixtures of volatile organics compounds. Chemsorb 1425 was challenged with various NH3 concentrations to determine its adsorptive capacity.

  15. 30 CFR 75.1000 - Cutout switches.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Trolley Wires and Trolley Feeder Wires § 75.1000 Cutout switches. [Statutory Provisions] Trolley wires and trolley feeder wires, shall be provided with cutout...

  16. 30 CFR 75.1000 - Cutout switches.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Trolley Wires and Trolley Feeder Wires § 75.1000 Cutout switches. [Statutory Provisions] Trolley wires and trolley feeder wires, shall be provided with cutout...

  17. 25 CFR 1000.355 - How are trust evaluations conducted?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false How are trust evaluations conducted? 1000.355 Section... EDUCATION ACT Trust Evaluation Review Annual Trust Evaluations § 1000.355 How are trust evaluations conducted? (a) Each year the Secretary's designated representative(s) will conduct trust evaluations for...

  18. AP1000{sup R} licensing and deployment in the United States

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jordan, R. P.; Russ, P. A.; Filiak, P. P.

    2012-07-01

    In recent years, both domestic and foreign utilities have turned to the standardized Westinghouse AP1000 plant design in satisfying their near - and long-term - sustainable energy needs. As direct support to these actions, licensing the AP1000 design has played a significant role by providing one of the fundamental bases in clearing regulatory hurdles leading to the start of new plant construction. Within the U.S. alone, Westinghouse AP1000 licensing activities have reached unprecedented milestones with the approvals of both AP1000 Design Certification and Southern Company's combined construction permit and operating license (COL) application directly supporting the construction of two newmore » nuclear plants in Georgia. Further COL application approvals are immediately pending for an additional two AP1000 plants in South Carolina. And, across the U.S. nuclear industry spectrum, there are 10 other COL applications under regulatory review representing some 16 new plants at 10 sites. In total, these actions represent the first wave of new plant licensing under the regulatory approval process since 1978. Fundamental to the Nuclear Regulatory Commission's AP1000 Design Certification is the formal recognition of the AP1000 passive safety design through regulatory acceptance rulemaking. Through recognition and deployment of the AP1000 Design Certification, the utility licensee / operator of this reactor design are now offered an opportunity to use a simplified 'one-step' combined license process, thereby managing substantial back-end construction schedule risk from regulatory and intervention delays. Application of this regulatory philosophy represents both acceptance and encouragement of standardized reactor designs like the AP1000. With the recent AP1000 Design Certification and utility COL acceptances, the fundamental licensing processes of this philosophy have successfully proven the attainment of significant milestones with the next stage licensing actions

  19. NOSD-1000, the high-temperature nitrous oxide spectroscopic databank

    NASA Astrophysics Data System (ADS)

    Tashkun, S. A.; Perevalov, V. I.; Lavrentieva, N. N.

    2016-07-01

    We present a high-temperature version, NOSD-1000, of the nitrous oxide spectroscopic databank. The databank contains the line parameters (positions, intensities, air- and self-broadened half-widths and coefficients of temperature dependence of air- and self-broadened half-widths) of the most abundant isotopologue 14N216O of the nitrous oxide molecule. The reference temperature is Tref=1000 K and the intensity cutoff is Icut=10-25 cm-1/(molecule cm-2). More than 1.4 million lines covering the 260-8310 cm-1 spectral range are included in NOSD-1000. The databank has been generated within the framework of the method of effective operators and based on the global fittings of spectroscopic parameters (parameters of the effective Hamiltonian and effective dipole moment operators) to observed data collected from the literature. Line-by-line simulation of a medium-resolution high-temperature (T=873 K) spectrum has been performed in order to validate the databank. NOSD-1000 is freely accessible via the Internet.

  20. The 1000 bull genome project

    USDA-ARS?s Scientific Manuscript database

    To meet growing global demands for high value protein from milk and meat, rates of genetic gain in domestic cattle must be accelerated. At the same time, animal health and welfare must be considered. The 1000 bull genomes project supports these goals by providing annotated sequence variants and ge...

  1. 24 CFR 1000.8 - May provisions of these regulations be waived?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false May provisions of these regulations be waived? 1000.8 Section 1000.8 Housing and Urban Development Regulations Relating to Housing and... HOUSING AND URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.8 May provisions of these...

  2. 16 CFR § 1000.28 - Directorate for Economic Analysis.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Directorate for Economic Analysis. § 1000... ORGANIZATION AND FUNCTIONS § 1000.28 Directorate for Economic Analysis. The Directorate for Economic Analysis, which is managed by the Associate Executive Director for Economic Analysis, is responsible for providing...

  3. 16 CFR § 1000.30 - Directorate for Laboratory Sciences.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Directorate for Laboratory Sciences. § 1000... ORGANIZATION AND FUNCTIONS § 1000.30 Directorate for Laboratory Sciences. The Directorate for Laboratory Sciences, which is managed by the Associate Executive Director for Laboratory Sciences, is responsible for...

  4. 16 CFR 1000.22 - Office of Human Resources Management.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Office of Human Resources Management. 1000... ORGANIZATION AND FUNCTIONS § 1000.22 Office of Human Resources Management. The Office of Human Resources Management, which is managed by the Director of the Office, provides human resources management support to...

  5. 16 CFR 1000.22 - Office of Human Resources Management.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Office of Human Resources Management. 1000... ORGANIZATION AND FUNCTIONS § 1000.22 Office of Human Resources Management. The Office of Human Resources Management, which is managed by the Director of the Office, provides human resources management support to...

  6. 16 CFR 1000.22 - Office of Human Resources Management.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Office of Human Resources Management. 1000... ORGANIZATION AND FUNCTIONS § 1000.22 Office of Human Resources Management. The Office of Human Resources Management, which is managed by the Director of the Office, provides human resources management support to...

  7. 16 CFR 1000.22 - Office of Human Resources Management.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Office of Human Resources Management. 1000... ORGANIZATION AND FUNCTIONS § 1000.22 Office of Human Resources Management. The Office of Human Resources Management, which is managed by the Director of the Office, provides human resources management support to...

  8. 16 CFR § 1000.27 - Directorate for Health Sciences.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Directorate for Health Sciences. § 1000.27... AND FUNCTIONS § 1000.27 Directorate for Health Sciences. The Directorate for Health Sciences is managed by the Associate Executive Director for Health Sciences and is responsible for reviewing and...

  9. Test Report for NG Sensors GTX-1000

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Manginell, Ronald P.

    2014-12-01

    This report describes initial testing of the NG Sensor GTX-1000 natural gas monitoring system. This testing showed that the retention time, peak area stability and heating value repeatability of the GTX-1000 were promising for natural gas measurements in the field or at the well head. The repeatability can be less than 0.25% for LHV and HHV for the Airgas standard tested in this report, which is very promising for a first generation prototype. Ultimately this system should be capable of 0.1% repeatability in heating value at significant size and power reductions compared with competing systems.

  10. Evaluation of glyphosate resistance in Arabidopsis thaliana expressing an altered target site EPSPS

    PubMed Central

    You, Jinsong; Qi, Youlin; Flasinski, Stanislaw; Kavanaugh, Christina; Washam, Jeannie; Ostrander, Elizabeth; Wang, Dafu; Heck, Greg

    2017-01-01

    Abstract BACKGROUND Glyphosate‐resistant goosegrass has recently evolved and is homozygous for the double mutant of EPSPS (T102I, P106S or TIPS). These same mutations combined with EPSPS overexpression, have been used to create transgenic glyphosate‐resistant crops. Arabidopsis thaliana (Wt EPSPS K i ∼ 0.5 μM) was engineered to express a variant AtEPSPS‐T102I, P106A (TIPA K i = 150 μM) to determine the resistance magnitude for a more potent variant EPSPS that might evolve in weeds. RESULTS Transgenic A. thaliana plants, homozygous for one, two or four copies of AtEPSPS‐TIPA, had resistance (IC50 values, R/S) as measured by seed production ranging from 4.3‐ to 16‐fold. Plants treated in reproductive stage were male sterile with a range of R/S from 10.1‐ to 40.6‐fold. A significant hormesis (∼ 63% gain in fresh weight) was observed for all genotypes when treated at the initiation of reproductive stage with 0.013 kg ha–1. AtEPSPS‐TIPA enzyme activity was proportional to copy number and correlated with resistance magnitude. CONCLUSIONS A. thaliana, as a model weed expressing one copy of AtEPSPS‐TIPA (300‐fold more resistant), had only 4.3‐fold resistance to glyphosate for seed production. Resistance behaved as a single dominant allele. Vegetative tissue resistance was 4.7‐fold greater than reproductive tissue resistance and was linear with gene copy number. © 2017 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. PMID:28677849

  11. 16 CFR § 1000.18 - Office of Executive Director.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Office of Executive Director. § 1000.18... AND FUNCTIONS § 1000.18 Office of Executive Director. The Executive Director with the assistance of... Commission policy, acts as the chief operating manager of the agency, supporting the development of the...

  12. 25 CFR 1000.40 - What is the purpose of this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... EDUCATION ACT Section 402(d) Planning and Negotiation Grants Purpose and Types of Grants § 1000.40 What is... 25 Indians 2 2010-04-01 2010-04-01 false What is the purpose of this subpart? 1000.40 Section 1000... planning and negotiation grants authorized by section 402(d) of the Act to help Tribes meet costs incurred...

  13. 25 CFR 1000.12 - What is a “signatory”?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What is a âsignatoryâ? 1000.12 Section 1000.12 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS... What is a “signatory”? A signatory is a Tribe or Consortium that meets the eligibility criteria in...

  14. 7 CFR 1000.9 - Handler.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... § 1000.9 Handler. Handler means: (a) Any person who operates a pool plant or a nonpool plant. (b) Any person who receives packaged fluid milk products from a plant for resale and distribution to retail or... cream products from or to any pool or nonpool plant, and any person who by purchase or direction causes...

  15. 16 CFR 1000.21 - Office of Compliance and Field Operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... enforces the Consumer Product Safety Act reporting requirements. It reviews consumer complaints, conducts.... 1000.21 Section 1000.21 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION... identifying and addressing safety hazards in consumer products already in distribution, promoting industry...

  16. 16 CFR 1000.21 - Office of Compliance and Field Operations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... enforces the Consumer Product Safety Act reporting requirements. It reviews consumer complaints, conducts.... 1000.21 Section 1000.21 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION... identifying and addressing safety hazards in consumer products already in distribution, promoting industry...

  17. 16 CFR 1000.21 - Office of Compliance and Field Operations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... enforces the Consumer Product Safety Act reporting requirements. It reviews consumer complaints, conducts.... 1000.21 Section 1000.21 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION... identifying and addressing safety hazards in consumer products already in distribution, promoting industry...

  18. 16 CFR 1000.21 - Office of Compliance and Field Operations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... enforces the Consumer Product Safety Act reporting requirements. It reviews consumer complaints, conducts.... 1000.21 Section 1000.21 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION... identifying and addressing safety hazards in consumer products already in distribution, promoting industry...

  19. 16 CFR 1000.20 - Office of Information and Public Affairs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... 1000.20 Section 1000.20 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION..., implementation, and evaluation of a comprehensive national information and public affairs program designed to... range of national groups such as consumer organizations; business groups; trade associations; state and...

  20. 24 CFR 1000.503 - What is an appropriate extent of HUD monitoring?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES Recipient Monitoring, Oversight and Accountability § 1000.503 What is an appropriate extent of HUD monitoring? (a) Subject to any... HUD monitoring? 1000.503 Section 1000.503 Housing and Urban Development REGULATIONS RELATING TO...

  1. 24 CFR 1000.503 - What is an appropriate extent of HUD monitoring?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES Recipient Monitoring, Oversight and Accountability § 1000.503 What is an appropriate extent of HUD monitoring? (a) Subject to any... HUD monitoring? 1000.503 Section 1000.503 Housing and Urban Development REGULATIONS RELATING TO...

  2. Navy DDG-1000 Destroyer Program: Background, Oversight Issues, and Options for Congress

    DTIC Science & Technology

    2007-10-25

    production quantity of eight ships (one more than the Navy currently plans to procure). Shared Production Arrangement. NGSS and GD/BIW have agreed on a...X)). Navy plans call for procuring 7 DDG-1000s between FY2007 and FY2013. The first two DDG-1000s were procured in FY2007 and are being split...Congress for the DDG-1000 program include supporting the Navy’s proposed plans , using a block-buy arrangement for procuring several DDG-1000s, and

  3. HLA Diversity in the 1000 Genomes Dataset

    PubMed Central

    Gourraud, Pierre-Antoine; Khankhanian, Pouya; Cereb, Nezih; Yang, Soo Young; Feolo, Michael; Maiers, Martin; D. Rioux, John; Hauser, Stephen; Oksenberg, Jorge

    2014-01-01

    The 1000 Genomes Project aims to provide a deep characterization of human genome sequence variation by sequencing at a level that should allow the genome-wide detection of most variants with frequencies as low as 1%. However, in the major histocompatibility complex (MHC), only the top 10 most frequent haplotypes are in the 1% frequency range whereas thousands of haplotypes are present at lower frequencies. Given the limitation of both the coverage and the read length of the sequences generated by the 1000 Genomes Project, the highly variable positions that define HLA alleles may be difficult to identify. We used classical Sanger sequencing techniques to type the HLA-A, HLA-B, HLA-C, HLA-DRB1 and HLA-DQB1 genes in the available 1000 Genomes samples and combined the results with the 103,310 variants in the MHC region genotyped by the 1000 Genomes Project. Using pairwise identity-by-descent distances between individuals and principal component analysis, we established the relationship between ancestry and genetic diversity in the MHC region. As expected, both the MHC variants and the HLA phenotype can identify the major ancestry lineage, informed mainly by the most frequent HLA haplotypes. To some extent, regions of the genome with similar genetic or similar recombination rate have similar properties. An MHC-centric analysis underlines departures between the ancestral background of the MHC and the genome-wide picture. Our analysis of linkage disequilibrium (LD) decay in these samples suggests that overestimation of pairwise LD occurs due to a limited sampling of the MHC diversity. This collection of HLA-specific MHC variants, available on the dbMHC portal, is a valuable resource for future analyses of the role of MHC in population and disease studies. PMID:24988075

  4. HLA diversity in the 1000 genomes dataset.

    PubMed

    Gourraud, Pierre-Antoine; Khankhanian, Pouya; Cereb, Nezih; Yang, Soo Young; Feolo, Michael; Maiers, Martin; Rioux, John D; Hauser, Stephen; Oksenberg, Jorge

    2014-01-01

    The 1000 Genomes Project aims to provide a deep characterization of human genome sequence variation by sequencing at a level that should allow the genome-wide detection of most variants with frequencies as low as 1%. However, in the major histocompatibility complex (MHC), only the top 10 most frequent haplotypes are in the 1% frequency range whereas thousands of haplotypes are present at lower frequencies. Given the limitation of both the coverage and the read length of the sequences generated by the 1000 Genomes Project, the highly variable positions that define HLA alleles may be difficult to identify. We used classical Sanger sequencing techniques to type the HLA-A, HLA-B, HLA-C, HLA-DRB1 and HLA-DQB1 genes in the available 1000 Genomes samples and combined the results with the 103,310 variants in the MHC region genotyped by the 1000 Genomes Project. Using pairwise identity-by-descent distances between individuals and principal component analysis, we established the relationship between ancestry and genetic diversity in the MHC region. As expected, both the MHC variants and the HLA phenotype can identify the major ancestry lineage, informed mainly by the most frequent HLA haplotypes. To some extent, regions of the genome with similar genetic or similar recombination rate have similar properties. An MHC-centric analysis underlines departures between the ancestral background of the MHC and the genome-wide picture. Our analysis of linkage disequilibrium (LD) decay in these samples suggests that overestimation of pairwise LD occurs due to a limited sampling of the MHC diversity. This collection of HLA-specific MHC variants, available on the dbMHC portal, is a valuable resource for future analyses of the role of MHC in population and disease studies.

  5. 1,000 Wells for Darfur

    NASA Astrophysics Data System (ADS)

    Virji, Hassan

    2007-08-01

    A new humanitarian mission called ``1,000 Wells for Darfur'' grew out of the discovery from recent space data of an ancient megalake in a large basin in that region. Eman Ghoneim, a research professor at Boston University's Center for Remote Sensing, and Center director Farouk El-Baz mapped the ancient lake's boundary using Landsat, RADARSAT, and Shuttle Radar Topography Mission (SRTM) data.

  6. 24 CFR 1000.128 - Is income verification required for assistance under NAHASDA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Is income verification required for assistance under NAHASDA? 1000.128 Section 1000.128 Housing and Urban Development Regulations Relating to... § 1000.128 Is income verification required for assistance under NAHASDA? (a) Yes, the recipient must...

  7. 24 CFR 1000.48 - Are Indian preference requirements applicable to IHBG activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Are Indian preference requirements applicable to IHBG activities? 1000.48 Section 1000.48 Housing and Urban Development Regulations Relating to..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.48 Are Indian...

  8. The ELIXIR channel in F1000Research.

    PubMed

    Blomberg, Niklas; Oliveira, Arlindo; Mons, Barend; Persson, Bengt; Jonassen, Inge

    2015-01-01

    ELIXIR, the European life science infrastructure for biological information, is a unique initiative to consolidate Europe's national centres, services, and core bioinformatics resources into a single, coordinated infrastructure. ELIXIR brings together Europe's major life-science data archives and connects these with national bioinformatics infrastructures  - the ELIXIR Nodes. This editorial introduces the ELIXIR channel in F1000Research; the aim of the channel is to collect and present ELIXIR's scientific and operational output, engage with the broad life science community and encourage discussion on proposed infrastructure solutions. Submissions will be assessed by the ELIXIR channel Advisory Board to ensure they are relevant to ELIXIR community, and subjected to F1000Research open peer review process.

  9. 24 CFR 1000.404 - What lenders are eligible for participation?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What lenders are eligible for participation? 1000.404 Section 1000.404 Housing and Urban Development Regulations Relating to Housing and Urban... URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES Federal Guarantees for Financing of Tribal Housing...

  10. 30 CFR 285.1000 - What activities does this subpart regulate?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CONTINENTAL SHELF Rights of Use and Easement for Energy- and Marine-Related Activities Using Existing OCS... existing OCS facility for energy- or marine-related purposes, that are not otherwise authorized under any....1000 Section 285.1000 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT...

  11. 30 CFR 585.1000 - What activities does this subpart regulate?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... of Use and Easement for Energy- and Marine-Related Activities Using Existing OCS Facilities Regulated... for energy- or marine-related purposes, that are not otherwise authorized under any other part of this....1000 Section 585.1000 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR...

  12. 30 CFR 585.1000 - What activities does this subpart regulate?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... of Use and Easement for Energy- and Marine-Related Activities Using Existing OCS Facilities Regulated... for energy- or marine-related purposes, that are not otherwise authorized under any other part of this....1000 Section 585.1000 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR...

  13. 30 CFR 585.1000 - What activities does this subpart regulate?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... of Use and Easement for Energy- and Marine-Related Activities Using Existing OCS Facilities Regulated... for energy- or marine-related purposes, that are not otherwise authorized under any other part of this....1000 Section 585.1000 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR...

  14. 24 CFR 1000.6 - What is the nature of the IHBG program?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false What is the nature of the IHBG program? 1000.6 Section 1000.6 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN... URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.6 What is the nature of the IHBG...

  15. 24 CFR 1000.6 - What is the nature of the IHBG program?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false What is the nature of the IHBG program? 1000.6 Section 1000.6 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN... URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.6 What is the nature of the IHBG...

  16. 25 CFR 115.1000 - Who owns the records associated with this part?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Who owns the records associated with this part? 115.1000 Section 115.1000 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES TRUST FUNDS FOR TRIBES AND INDIVIDUAL INDIANS Records § 115.1000 Who owns the records associated with this...

  17. 24 CFR 1000.6 - What is the nature of the IHBG program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What is the nature of the IHBG program? 1000.6 Section 1000.6 Housing and Urban Development Regulations Relating to Housing and Urban... URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.6 What is the nature of the IHBG...

  18. 24 CFR 1000.6 - What is the nature of the IHBG program?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false What is the nature of the IHBG program? 1000.6 Section 1000.6 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN... URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.6 What is the nature of the IHBG...

  19. 24 CFR 1000.6 - What is the nature of the IHBG program?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false What is the nature of the IHBG program? 1000.6 Section 1000.6 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN... URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.6 What is the nature of the IHBG...

  20. 25 CFR 166.1000 - Who owns the records associated with this part?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Who owns the records associated with this part? 166.1000 Section 166.1000 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GRAZING PERMITS Records § 166.1000 Who owns the records associated with this part? (a) Records are the property of...

  1. RE-1000 free-piston Stirling engine hydraulic output system description

    NASA Technical Reports Server (NTRS)

    Schreiber, Jeffrey G.; Geng, Steven M.

    1987-01-01

    The NASA Lewis Research Center was involved in free-piston Stirling engine research since 1976. Most of the work performed in-house was related to characterization of the RE-1000 engine. The data collected from the RE-1000 tests were intended to provide a data base for the validation of Stirling cycle simulations. The RE-1000 was originally build with a dashpot load system which did not convert the output of the engine into useful power, but was merely used as a load for the engine to work against during testing. As part of the interagency program between NASA Lewis and the Oak Ridge National Laboratory, (ORNL), the RE-1000 was converted into a configuration that produces useable hydraulic power. A goal of the hydraulic output conversion effort was to retain the same thermodynamic cycle that existed with the dashpot loaded engine. It was required that the design must provide a hermetic seal between the hydraulic fluid and the working gas of the engine. The design was completed and the hardware was fabricated. The RE-1000 was modified in 1985 to the hydraulic output configuration. The early part of the RE-1000 hydraulic output program consisted of modifying hardware and software to allow the engine to run at steady-state conditions. A complete description of the engine is presented in sufficient detail so that the device can be simulated on a computer. Tables are presented showing the masses of the oscillating components and key dimensions needed for modeling purposes. Graphs are used to indicate the spring rate of the diaphragms used to separate the helium of the working and bounce space from the hydraulic fluid.

  2. 24 CFR 1000.4 - What are the objectives of NAHASDA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... infrastructure resources for Indian tribes with housing development for Indian tribes; and (e) To promote the... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What are the objectives of NAHASDA? 1000.4 Section 1000.4 Housing and Urban Development Regulations Relating to Housing and Urban...

  3. The ELIXIR channel in F1000Research

    PubMed Central

    Blomberg, Niklas; Oliveira, Arlindo; Mons, Barend; Persson, Bengt; Jonassen, Inge

    2016-01-01

    ELIXIR, the European life science infrastructure for biological information, is a unique initiative to consolidate Europe’s national centres, services, and core bioinformatics resources into a single, coordinated infrastructure. ELIXIR brings together Europe’s major life-science data archives and connects these with national bioinformatics infrastructures  - the ELIXIR Nodes. This editorial introduces the ELIXIR channel in F1000Research; the aim of the channel is to collect and present ELIXIR’s scientific and operational output, engage with the broad life science community and encourage discussion on proposed infrastructure solutions. Submissions will be assessed by the ELIXIR channel Advisory Board to ensure they are relevant to ELIXIR community, and subjected to F1000Research open peer review process. PMID:26913192

  4. ASD-1000: High-resolution, high-temperature acetylene spectroscopic databank

    NASA Astrophysics Data System (ADS)

    Lyulin, O. M.; Perevalov, V. I.

    2017-11-01

    We present a high-resolution, high-temperature version of the Acetylene Spectroscopic Databank called ASD-1000. The databank contains the line parameters (position, intensity, Einstein coefficient for spontaneous emission, term value of the lower states, self- and air-broadening coefficients, temperature dependence exponents of the self- and air-broadening coefficients) of the principal isotopologue of C2H2. The reference temperature for line intensity is 296 K and the intensity cutoff is 10-27 cm-1/(molecule cm-2) at 1000 K. The databank has 33,890,981 entries and covers the 3-10,000 cm-1 spectral range. The databank is based on the global modeling of the line positions and intensities performed within the framework of the method of effective operators. The parameters of the effective Hamiltonian and the effective dipole moment operator have been fitted to the observed values of the line positions and intensities collected from the literature. The broadening coefficients as well as their temperature dependence exponents were calculated using the empirical equations. The databank is useful for studying high-temperature radiative properties of C2H2. ASD-1000 is freely accessible via the Internet site of V.E. Zuev Institute of Atmospheric Optics SB RAS ftp://ftp.iao.ru/pub/ASD1000/.

  5. NDSD-1000: High-resolution, high-temperature Nitrogen Dioxide Spectroscopic Databank

    NASA Astrophysics Data System (ADS)

    Lukashevskaya, A. A.; Lavrentieva, N. N.; Dudaryonok, A. C.; Perevalov, V. I.

    2016-11-01

    We present a high-resolution, high-temperature version of the Nitrogen Dioxide Spectroscopic Databank called NDSD-1000. The databank contains the line parameters (positions, intensities, self- and air-broadening coefficients, exponents of the temperature dependence of self- and air-broadening coefficients) of the principal isotopologue of NO2. The reference temperature for line intensity is 296 K and the intensity cutoff is 10-25 cm-1/molecule cm-2 at 1000 K. The broadening parameters are presented for two reference temperatures 296 K and 1000 K. The databank has 1,046,808 entries, covers five spectral regions in the 466-4776 cm-1 spectral range and is designed for temperatures up to 1000 K. The databank is based on the global modeling of the line positions and intensities performed within the framework of the method of effective operators. The parameters of the effective Hamiltonian and the effective dipole moment operator have been fitted to the observed values of the line positions and intensities collected from the literature. The broadening coefficients as well as the temperature exponents are calculated using the semi-empirical approach. The databank is useful for studying high-temperature radiative properties of NO2. NDSD-1000 is freely accessible via the internet site of V.E. Zuev Institute of Atmospheric Optics SB RAS ftp://ftp.iao.ru/pub/NDSD/.

  6. 25 CFR 1000.105 - What are self-governance base budgets?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What are self-governance base budgets? 1000.105 Section... Base Budgets § 1000.105 What are self-governance base budgets? (a) A Tribe/Consortium self-governance base budget is the amount of recurring funding identified in the President's annual budget request to...

  7. Complications after 1000 lung radiofrequency ablation sessions in 420 patients: a single center's experiences.

    PubMed

    Kashima, Masataka; Yamakado, Koichiro; Takaki, Haruyuki; Kodama, Hiroshi; Yamada, Tomomi; Uraki, Junji; Nakatsuka, Atsuhiro

    2011-10-01

    This study retrospectively evaluates complications after lung radiofrequency ablation (RFA). Complications were assessed for each RFA session in 420 consecutive patients with 1403 lung tumors who underwent 1000 RFA sessions with a cool-tip RFA system. A major complication was defined as a grade 3 or 4 adverse event. Risk factors affecting frequent major complications that occurred with an incidence of 1% or more were detected using multivariate analysis. Four deaths (0.4% [4/1000]) related to RFA procedures occurred. Three patients died of interstitial pneumonia. The other patient died of hemothorax. The major complication rate was 9.8% (98/1000). Frequent major complications were aseptic pleuritis (2.3% [23/1000]), pneumonia (1.8% [18/1000]), lung abscess (1.6% [16/1000]), bleeding requiring blood transfusion (1.6% [16/1000]), pneumothorax requiring pleural sclerosis (1.6% [16/1000]), followed by bronchopleural fistula (0.4% [4/1000]), brachial nerve injury (0.3% [3/1000]), tumor seeding (0.1% [1/1000]), and diaphragm injury (0.1% [1/1000]). Puncture number (p < 0.02) and previous systemic chemotherapy (p < 0.05) were significant risk factors for aseptic pleuritis. Previous external beam radiotherapy (p < 0.001) and age (p < 0.02) were significant risk factors for pneumonia, as were emphysema (p < 0.02) for lung abscess, and serum platelet count (p < 0.002) and tumor size (p < 0.02) for bleeding. Emphysema (p < 0.02) was a significant risk factor for pneumothorax requiring pleural sclerosis. Lung RFA is a relatively safe procedure, but it can be fatal. Risk factors found in this study will help to stratify high-risk patients.

  8. 49 CFR 232.207 - Class IA brake tests-1,000-mile inspection.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Class IA brake tests-1,000-mile inspection. 232... Class IA brake tests—1,000-mile inspection. (a) Except as provided in § 232.213, each train shall... is not more than 1,000 miles from the point where any car in the train last received a Class I or...

  9. 49 CFR 232.207 - Class IA brake tests-1,000-mile inspection.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Class IA brake tests-1,000-mile inspection. 232... Class IA brake tests—1,000-mile inspection. (a) Except as provided in § 232.213, each train shall... is not more than 1,000 miles from the point where any car in the train last received a Class I or...

  10. 49 CFR 232.207 - Class IA brake tests-1,000-mile inspection.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Class IA brake tests-1,000-mile inspection. 232... Class IA brake tests—1,000-mile inspection. (a) Except as provided in § 232.213, each train shall... is not more than 1,000 miles from the point where any car in the train last received a Class I or...

  11. 48 CFR 3.1000 - Scope of subpart.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contractor Code of Business Ethics and Conduct 3.1000... codes of business ethics and conduct, and display of agency Office of Inspector General (OIG) fraud...

  12. 24 CFR 1000.32 - May exceptions be made to the conflict of interest provisions?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... conflict of interest provisions? 1000.32 Section 1000.32 Housing and Urban Development Regulations Relating... HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.32... conflict of interest provisions set forth in § 1000.30(b) on a case-by-case basis when it determines that...

  13. Comparison of the new biometer OA-1000 with IOLMaster and Tomey AL-3000.

    PubMed

    Goebels, Susanne Christiane; Seitz, Berthold; Langenbucher, Achim

    2013-09-01

    The OA-1000 (Tomey, Japan) is a new optical biometer, which allows measurements of axial length (AL), anterior chamber depth (ACD) and corneal thickness (CT) due to partial coherence interferometry (PCI) technology. The aim of this study was to compare the OA-1000 results with those obtained with the IOLMaster and contact applanation A-scan ultrasonography. We examined 133 eyes of 75 patients with age related cataract. Mean age was 72.0 ± 9.5 years. Biometry measurements of AL and ACD were performed with the Tomey OA-1000 based on PCI, the IOLMaster based on PCI (AL) and slit projection (ACD), and the Tomey AL-3000 based on contact applanation A-scan ultrasonography. Mean AL using the IOLMaster was 23.21 ± 1.08 mm, using the AL-3000 was 22.79 ± 1.04 mm, using the OA-1000 it was 22.97 ± 1.1 mm. Mean ACD using the IOLMaster was 2.99 ± 0.41 mm, using the OA-1000 3.40 ± 0.46 mm, using the Tomey AL-3000 it was 2.93 ± 0.43 mm. Mean difference between the AL and ACD measured with the OA-1000 and the IOLMaster was 0.22 ± 0.047 mm and 0.40 ± 0.33 mm, between OA-1000 and the AL-3000 it was 0.19 ± 0.23 mm and 0.47 ± 0.33 mm, and between IOLMaster and AL-3000 it was 0.42 ± 0.23 and 0.09 ± 0.36 mm. For AL the correlation coefficient R between IOLMaster and OA-1000 was 0.999, between IOLMaster and AL-3000 it was 0.976, between AL-3000 and OA-1000 it was 0.977. For ACD R between IOLMaster and OA-1000 was 0.735, between IOLMaster and AL-3000 it was 0.822, between AL-3000 and OA-1000 it was 0.716 (all p < 0.001). Compared with other used clinical instruments the OA-1000 generates accurate results. Although differences were found, the OA-1000 provided results that correlated well with the values of IOLMaster and AL-3000.

  14. Injecting 1000 centistoke liquid silicone with ease and precision.

    PubMed

    Benedetto, Anthony V; Lewis, Alan T

    2003-03-01

    Since the Food and Drug Administration approved the use of the 1000 centistoke liquid silicone, Silikon 1000, for intraocular injection, the off-label use of this injectable silicone oil as a permanent soft-tissue filler for facial rejuvenation has increased in the United States. Injecting liquid silicone by the microdroplet technique is the most important preventive measure that one can use to avoid the adverse sequelae of silicone migration and granuloma formation, especially when injecting silicone to improve small facial defects resulting from acne scars, surgical procedures, or photoaging. To introduce an easy method for injecting a viscous silicone oil by the microdroplet technique, using an inexpensive syringe and needle that currently is available from distributors of medical supplies in the United States. We suggest the use of a Becton Dickinson 3/10 cc insulin U-100 syringe to inject Silikon 1000. This syringe contains up to 0.3 mL of fluid, and its barrel is clearly marked with an easy-to-read scale of large cross-hatches. Each cross-hatch marking represents either a unit value of 0.01 mL or a half-unit value of 0.005 mL of fluid, which is the approximate volume preferred when injecting liquid silicone into facial defects. Because not enough negative pressure can be generated in this needle and syringe to draw up the viscous silicone oil, we describe a convenient and easy method for filling this 3/10 cc diabetic syringe with Silikon 1000. We have found that by using the Becton Dickinson 3/10 cc insulin U-100 syringe, our technique of injecting minute amounts of Silikon 1000 is facilitated because each widely spaced cross-hatch on the side of the syringe barrel is easy to read and measures exact amounts of the silicone oil. These lines of the scale on the syringe barrel are so large and clearly marked that it is virtually impossible to overinject the most minute amount of silicone. Sequential microdroplets of 0.01 cc or less of Silikon 1000 can be

  15. 24 CFR 1000.14 - What relocation and real property acquisition policies are applicable?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What relocation and real property acquisition policies are applicable? 1000.14 Section 1000.14 Housing and Urban Development Regulations... HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.14...

  16. 24 CFR 1000.50 - What Indian preference requirements apply to IHBG administration activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What Indian preference requirements apply to IHBG administration activities? 1000.50 Section 1000.50 Housing and Urban Development... § 1000.50 What Indian preference requirements apply to IHBG administration activities? To the greatest...

  17. 25 CFR 1000.381 - How is information about self-governance developed and reported?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... the Congress. The report will be based on: (a) Audit reports routinely submitted by Tribes/Consortia... reported? 1000.381 Section 1000.381 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT... INDIAN SELF-DETERMINATION AND EDUCATION ACT Reports § 1000.381 How is information about self-governance...

  18. 25 CFR 1000.381 - How is information about self-governance developed and reported?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... the Congress. The report will be based on: (a) Audit reports routinely submitted by Tribes/Consortia... reported? 1000.381 Section 1000.381 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT... INDIAN SELF-DETERMINATION AND EDUCATION ACT Reports § 1000.381 How is information about self-governance...

  19. 25 CFR 1000.381 - How is information about self-governance developed and reported?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the Congress. The report will be based on: (a) Audit reports routinely submitted by Tribes/Consortia... reported? 1000.381 Section 1000.381 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT... INDIAN SELF-DETERMINATION AND EDUCATION ACT Reports § 1000.381 How is information about self-governance...

  20. 25 CFR 1000.381 - How is information about self-governance developed and reported?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... the Congress. The report will be based on: (a) Audit reports routinely submitted by Tribes/Consortia... reported? 1000.381 Section 1000.381 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT... INDIAN SELF-DETERMINATION AND EDUCATION ACT Reports § 1000.381 How is information about self-governance...

  1. 25 CFR 1000.381 - How is information about self-governance developed and reported?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... the Congress. The report will be based on: (a) Audit reports routinely submitted by Tribes/Consortia... reported? 1000.381 Section 1000.381 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT... INDIAN SELF-DETERMINATION AND EDUCATION ACT Reports § 1000.381 How is information about self-governance...

  2. 16 CFR § 1000.21 - Office of Compliance and Field Operations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... enforces the Consumer Product Safety Act reporting requirements. It reviews consumer complaints, conducts...§ 1000.21 Section § 1000.21 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION... identifying and addressing safety hazards in consumer products already in distribution, promoting industry...

  3. 24 CFR 1000.56 - How are NAHASDA funds paid by HUD to recipients?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false How are NAHASDA funds paid by HUD to recipients? 1000.56 Section 1000.56 Housing and Urban Development Regulations Relating to Housing..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.56 How are...

  4. 24 CFR 1000.126 - May a recipient charge flat or income-adjusted rents?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false May a recipient charge flat or income-adjusted rents? 1000.126 Section 1000.126 Housing and Urban Development Regulations Relating to... § 1000.126 May a recipient charge flat or income-adjusted rents? Yes, providing the rental or homebuyer...

  5. 25 CFR 1000.232 - When must DOI respond to a request for reconsideration?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false When must DOI respond to a request for reconsideration? 1000.232 Section 1000.232 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE...-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.232 When must DOI respond to a request for...

  6. 7 CFR 1000.45 - Market administrator's reports and announcements concerning classification.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Market administrator's reports and announcements... GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.45 Market administrator... corresponding step of § 1000.44(b), the market administrator shall estimate and publicly announce the...

  7. 24 CFR 1000.26 - What are the administrative requirements under NAHASDA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false What are the administrative requirements under NAHASDA? 1000.26 Section 1000.26 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN HOUSING...

  8. Evaluation of the MIT RMID 1000 system for the identification of Listeria species.

    PubMed

    Ricardi, John; Haavig, David; Cruz, Lasaunta; Paoli, George; Gehring, Andrew

    2010-01-01

    The Micro Imaging Technology (MIT) 1000 Rapid Microbial Identification (RMID) System is a device that uses the principles of light scattering coupled with proprietary algorithms to identify bacteria after being cultured and placed in a vial of filtered water. This specific method is for pure culture identification of Listeria spp. A total of 81 microorganisms (55 isolates) were tested by the MIT 1000 System, of which 25 were Listeria spp. and 30 a variety of other bacterial species. In addition, a total of 406 tests over seven different ruggedness parameters were tested by the MIT 1000 System to determine its flexibility to the specifications stated in the MIT 1000 System User Guide in areas where they might be deviated by a user to shorten the test cycle. Overall, MIT concluded that the MIT 1000 System had an accuracy performance that should certify this Performance Test Method for the identification of Listeria spp. This report discusses the tests performed, results achieved, and conclusions, along with several reference documents to enable a higher understanding of the technology used by the MIT 1000 System.

  9. 25 CFR 1000.220 - What regulations apply to self-governance Tribes?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What regulations apply to self-governance Tribes? 1000... INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.220 What regulations apply to self-governance...

  10. 25 CFR 1000.220 - What regulations apply to self-governance Tribes?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false What regulations apply to self-governance Tribes? 1000.220 Section 1000.220 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE... Tribes? All regulations that govern the operation of programs included in an AFA apply unless waived...

  11. 25 CFR 1000.220 - What regulations apply to self-governance Tribes?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false What regulations apply to self-governance Tribes? 1000.220 Section 1000.220 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE... Tribes? All regulations that govern the operation of programs included in an AFA apply unless waived...

  12. 25 CFR 1000.220 - What regulations apply to self-governance Tribes?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false What regulations apply to self-governance Tribes? 1000.220 Section 1000.220 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE... Tribes? All regulations that govern the operation of programs included in an AFA apply unless waived...

  13. 25 CFR 1000.220 - What regulations apply to self-governance Tribes?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false What regulations apply to self-governance Tribes? 1000.220 Section 1000.220 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE... Tribes? All regulations that govern the operation of programs included in an AFA apply unless waived...

  14. The Westinghouse Series 1000 Mobile Phone: Technology and applications

    NASA Technical Reports Server (NTRS)

    Connelly, Brian

    1993-01-01

    Mobile satellite communications will be popularized by the North American Mobile Satellite (MSAT) system. The success of the overall system is dependent upon the quality of the mobile units. Westinghouse is designing our unit, the Series 1000 Mobile Phone, with the user in mind. The architecture and technology aim at providing optimum performance at a low per unit cost. The features and functions of the Series 1000 Mobile Phone have been defined by potential MSAT users. The latter portion of this paper deals with who those users may be.

  15. 24 CFR 1000.106 - What families receiving assistance under title II of NAHASDA require HUD approval?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... under title II of NAHASDA require HUD approval? 1000.106 Section 1000.106 Housing and Urban Development... Housing Activities § 1000.106 What families receiving assistance under title II of NAHASDA require HUD... in §§ 1000.108 and 1000.110. (b) Assistance under section 201(b)(3) of NAHASDA for non-Indian...

  16. 25 CFR 1000.109 - How are self-governance base budgets adjusted?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false How are self-governance base budgets adjusted? 1000.109... Self-Governance Base Budgets § 1000.109 How are self-governance base budgets adjusted? Self-governance base budgets must be adjusted as follows: (a) Congressional action. (1) Increases/decreases as a result...

  17. 25 CFR 1000.108 - How are self-governance base budgets established?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false How are self-governance base budgets established? 1000... Self-Governance Base Budgets § 1000.108 How are self-governance base budgets established? At the request of the Tribe/Consortium, a self-governance base budget identifying each Tribe's funding amount is...

  18. 25 CFR 1000.109 - How are self-governance base budgets adjusted?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false How are self-governance base budgets adjusted? 1000.109... Self-Governance Base Budgets § 1000.109 How are self-governance base budgets adjusted? Self-governance base budgets must be adjusted as follows: (a) Congressional action. (1) Increases/decreases as a result...

  19. 25 CFR 1000.109 - How are self-governance base budgets adjusted?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false How are self-governance base budgets adjusted? 1000.109... Self-Governance Base Budgets § 1000.109 How are self-governance base budgets adjusted? Self-governance base budgets must be adjusted as follows: (a) Congressional action. (1) Increases/decreases as a result...

  20. 25 CFR 1000.108 - How are self-governance base budgets established?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false How are self-governance base budgets established? 1000... Self-Governance Base Budgets § 1000.108 How are self-governance base budgets established? At the request of the Tribe/Consortium, a self-governance base budget identifying each Tribe's funding amount is...

  1. 25 CFR 1000.108 - How are self-governance base budgets established?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false How are self-governance base budgets established? 1000... Self-Governance Base Budgets § 1000.108 How are self-governance base budgets established? At the request of the Tribe/Consortium, a self-governance base budget identifying each Tribe's funding amount is...

  2. 25 CFR 1000.109 - How are self-governance base budgets adjusted?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false How are self-governance base budgets adjusted? 1000.109... Self-Governance Base Budgets § 1000.109 How are self-governance base budgets adjusted? Self-governance base budgets must be adjusted as follows: (a) Congressional action. (1) Increases/decreases as a result...

  3. 25 CFR 1000.108 - How are self-governance base budgets established?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false How are self-governance base budgets established? 1000... Self-Governance Base Budgets § 1000.108 How are self-governance base budgets established? At the request of the Tribe/Consortium, a self-governance base budget identifying each Tribe's funding amount is...

  4. 25 CFR 1000.303 - What is imminent jeopardy to natural resources?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false What is imminent jeopardy to natural resources? 1000.303...-DETERMINATION AND EDUCATION ACT Reassumption § 1000.303 What is imminent jeopardy to natural resources? The standard for natural resources is the same as for a physical trust asset, except that a review for...

  5. 25 CFR 1000.303 - What is imminent jeopardy to natural resources?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false What is imminent jeopardy to natural resources? 1000.303...-DETERMINATION AND EDUCATION ACT Reassumption § 1000.303 What is imminent jeopardy to natural resources? The standard for natural resources is the same as for a physical trust asset, except that a review for...

  6. 25 CFR 1000.303 - What is imminent jeopardy to natural resources?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false What is imminent jeopardy to natural resources? 1000.303...-DETERMINATION AND EDUCATION ACT Reassumption § 1000.303 What is imminent jeopardy to natural resources? The standard for natural resources is the same as for a physical trust asset, except that a review for...

  7. 25 CFR 1000.303 - What is imminent jeopardy to natural resources?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What is imminent jeopardy to natural resources? 1000.303...-DETERMINATION AND EDUCATION ACT Reassumption § 1000.303 What is imminent jeopardy to natural resources? The standard for natural resources is the same as for a physical trust asset, except that a review for...

  8. 25 CFR 1000.303 - What is imminent jeopardy to natural resources?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false What is imminent jeopardy to natural resources? 1000.303...-DETERMINATION AND EDUCATION ACT Reassumption § 1000.303 What is imminent jeopardy to natural resources? The standard for natural resources is the same as for a physical trust asset, except that a review for...

  9. AP1000{sup R} severe accident features and post-Fukushima considerations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scobel, J. H.; Schulz, T. L.; Williams, M. G.

    2012-07-01

    The AP1000{sup R} passive nuclear power plant is uniquely equipped to withstand an extended station blackout scenario such as the events following the earthquake and tsunami at Fukushima without compromising core and containment integrity. The AP1000 plant shuts down the reactor, cools the core, containment and spent fuel pool for more than 3 days using passive systems that do not require AC or DC power or operator actions. Following this passive coping period, minimal operator actions are needed to extend the operation of the passive features to 7 days using installed equipment. To provide defense-in-depth for design extension conditions, themore » AP1000 plant has engineered features that mitigate the effects of core damage. Engineered features retain damaged core debris within the reactor vessel as a key feature. Other aspects of the design protect containment integrity during severe accidents, including unique features of the AP1000 design relative to passive containment cooling with water and air, and hydrogen management. (authors)« less

  10. Introducing iron isomaltoside 1000 (Monofer®)-development rationale and clinical experience.

    PubMed

    Kalra, Philip A

    2011-06-01

    Patients with chronic kidney disease (CKD) often suffer from iron deficiency anaemia necessitating treatment with intravenous (IV) iron. Several studies demonstrate that oral iron is insufficient in these patients and that IV supplementation is a more effective treatment. Until now, use of available parenteral iron preparations has been limited by dosing schedules and the need, in some cases, for a test dose, and despite the availability of a range of different IV iron compounds, there is still a need for improved compounds. The new IV iron, iron isomaltoside 1000 Monofer®, is composed of iron and chemically modified isomalto-oligosaccharides which have a mean molecular weight of 1000 Da and consist predominantly of 3-5 glucose units. In contrast to dextrans, the carbohydrate isomaltoside 1000 is a linear and unbranched structure with theoretically a low immunological potential. Hence, a test dose is not necessary. Iron isomaltoside 1000 contains strongly bound iron within the iron-isomaltoside formulation, which enables a controlled slow release of bioavailable iron to the iron-binding proteins, with potentially a reduced risk of free iron toxicity. This allows flexible dosing including high and rapid dosing securing convenient iron therapy for a wide range of patients. The development of Monofer® has been enthusiastically acknowledged by clinicians, and in 2009, there has been fast approval by European authorities via a decentralized registration procedure. This new IV iron is currently being marketed in several European countries. This article describes the development rationale and summarizes the clinical data assessing the use of iron isomaltoside 1000 administered without a test dose by either repeated bolus injections or fast high single iron infusions [defined as total dose infusion (TDI)] to patients suffering from CKD. Since CKD is associated with a high prevalence of cardiovascular disease, data from a small trial applying high single doses of iron

  11. 24 CFR 1000.112 - How will HUD determine whether to approve model housing activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false How will HUD determine whether to approve model housing activities? 1000.112 Section 1000.112 Housing and Urban Development Regulations... Activities § 1000.112 How will HUD determine whether to approve model housing activities? HUD will review all...

  12. 24 CFR 1000.22 - Are the costs of the environmental review an eligible cost?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Are the costs of the environmental review an eligible cost? 1000.22 Section 1000.22 Housing and Urban Development Regulations Relating to..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.22 Are the...

  13. 25 CFR 1000.278 - Does this coverage extend to subcontractors of self-governance AFAs?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false Does this coverage extend to subcontractors of self-governance AFAs? 1000.278 Section 1000.278 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... INDIAN SELF-DETERMINATION AND EDUCATION ACT Federal Tort Claims § 1000.278 Does this coverage extend to...

  14. 7 CFR 1000.77 - Adjustment of accounts.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Payments for Milk § 1000.77 Adjustment of accounts. Whenever audit by the market administrator of any... due the market administrator from a handler, or due a handler from the market administrator, or due a producer or cooperative association from a handler, the market administrator shall promptly notify such...

  15. 7 CFR 1000.77 - Adjustment of accounts.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Payments for Milk § 1000.77 Adjustment of accounts. Whenever audit by the market administrator of any... due the market administrator from a handler, or due a handler from the market administrator, or due a producer or cooperative association from a handler, the market administrator shall promptly notify such...

  16. 7 CFR 1000.77 - Adjustment of accounts.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Payments for Milk § 1000.77 Adjustment of accounts. Whenever audit by the market administrator of any... due the market administrator from a handler, or due a handler from the market administrator, or due a producer or cooperative association from a handler, the market administrator shall promptly notify such...

  17. 7 CFR 1000.77 - Adjustment of accounts.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Payments for Milk § 1000.77 Adjustment of accounts. Whenever audit by the market administrator of any... due the market administrator from a handler, or due a handler from the market administrator, or due a producer or cooperative association from a handler, the market administrator shall promptly notify such...

  18. 7 CFR 1000.77 - Adjustment of accounts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Payments for Milk § 1000.77 Adjustment of accounts. Whenever audit by the market administrator of any... due the market administrator from a handler, or due a handler from the market administrator, or due a producer or cooperative association from a handler, the market administrator shall promptly notify such...

  19. CDC/1000: a Control Data Corporation remote batch terminal emulator for Hewlett-Packard minicomputers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Berg, D.E.

    1981-02-01

    The Control Data Corporation Type 200 User Terminal utilizes a unique communications protocol to provide users with batch mode remote terminal access to Control Data computers. CDC/1000 is a software subsystem that implements this protocol on Hewlett-Packard minicomputers running the Real Time Executive III, IV, or IVB operating systems. This report provides brief descriptions of the various software modules comprising CDC/1000, and contains detailed instructions for integrating CDC/1000 into the Hewlett Packard operating system and for operating UTERM, the user interface program for CDC/1000. 6 figures.

  20. 25 CFR 1000.22 - What are the consequences of having a material audit exception?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What are the consequences of having a material audit exception? 1000.22 Section 1000.22 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF...-Governance Eligibility § 1000.22 What are the consequences of having a material audit exception? If a Tribe...

  1. 46 CFR 153.1000 - Special operating requirements for cargoes reactive with water.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Special operating requirements for cargoes reactive with water. 153.1000 Section 153.1000 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS...

  2. 46 CFR 153.1000 - Special operating requirements for cargoes reactive with water.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Special operating requirements for cargoes reactive with water. 153.1000 Section 153.1000 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS...

  3. 46 CFR 153.1000 - Special operating requirements for cargoes reactive with water.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Special operating requirements for cargoes reactive with water. 153.1000 Section 153.1000 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS...

  4. Nursing 1000: a mosaic of lessons learned from patients.

    PubMed

    Quinlan-Colwell, Ann

    2010-09-01

    Throughout my nursing career, I have been most grateful for the education and lessons that I received from the many gifted women and men faculty in the nursing programs I attended. From learning how to give a bed bath and intramuscular injections to writing a doctoral research proposal, the information, wisdom, guidance, and resources they shared with me are invaluable. I also am fortunate to have had the privilege of caring for many patients from whom I also learned invaluable lessons. Together, this latter group of women and men formed the faculty of Nursing 1000. They are the patients who were instrumental in shaping me and my nursing career. Many of them are no longer alive, and all of our paths have diverged, yet they remain influential in how I work with patients on a daily basis. The lessons they taught me form a most special montage. This mosaic article is a way to share with others what the faculty of Nursing 1000 taught me. It is also, in a small way, a tribute to all of the unique men and women with whom, as a nurse, I have shared transpersonal caring experiences and from whom I have learned much. The faculty of Nursing 1000 is composed of a variety of patients for whom I cared and who taught me valuable lessons that guided me in how to better care for patients in the future. Although the Nursing 1000 faculty are no longer physically part of my life, each day they continue to influence how I interact with others. The lessons they taught form a very special mosaic. To protect their confidentiality, all patient names are pseudonyms.

  5. 77 FR 56241 - Notice of Withdrawal of Final Design Approval; Westinghouse Electric Company; Advanced Passive 1000

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0131] Notice of Withdrawal of Final Design Approval... final design approval (FDA) for the Advanced Passive 1000 (AP1000) design upon the completion of rulemaking for the amendment to the AP1000 design and the issuance of the amended AP1000 design certification...

  6. 24 CFR 1000.60 - Can HUD prevent improper expenditure of funds already disbursed to a recipient?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... expenditure of funds already disbursed to a recipient? 1000.60 Section 1000.60 Housing and Urban Development... § 1000.60 Can HUD prevent improper expenditure of funds already disbursed to a recipient? Yes. In accordance with the standards and remedies contained in § 1000.538 relating to substantial noncompliance, HUD...

  7. 7 CFR 1000.43 - General classification rules.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS... milk order and shall compute separately for each pool plant, for each handler described in § 1000.9(c... purposes of classifying all milk reported by a handler pursuant to § __.30 of each Federal milk order the...

  8. 7 CFR 1000.43 - General classification rules.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS... milk order and shall compute separately for each pool plant, for each handler described in § 1000.9(c... purposes of classifying all milk reported by a handler pursuant to § __.30 of each Federal milk order the...

  9. 24 CFR 1000.30 - What prohibitions regarding conflict of interest are applicable?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... conflict of interest are applicable? 1000.30 Section 1000.30 Housing and Urban Development Regulations... What prohibitions regarding conflict of interest are applicable? (a) Applicability. In the procurement..., the conflict of interest provisions of 24 CFR 85.36 shall apply. In all cases not governed by 24 CFR...

  10. Validation of circulating BNP level >1000 pg/ml in all-cause mortality: A retrospective study.

    PubMed

    Sakamoto, Daisuke; Sakamoto, Shigeru; Kanda, Tsugiyasu

    2015-08-01

    To determine the primary diseases and prognoses of patients with highly elevated levels of B-type natriuretic peptide (BNP; >1000 pg/ml), with or without heart failure. Medical records and echocardiograms of patients with BNP levels that fell within one of three predetermined categories (>1000 pg/ml, 200-1000 pg/ml and <200 pg/ml) were retrospectively reviewed. There were no significant between-group differences in duration of hospitalization. Patients with BNP levels >1000 pg/ml (n = 103) or 200-1000 pg/ml (n = 100) had significantly worse 3-year survival than those with BNP levels <200 pg/ml (n = 100). The majority of patients (64/103) in the BNP >1000 pg/ml group had heart failure. The main cause of death in patients with other causes of BNP levels >1000 pg/ml (39/103) was community acquired pneumonia. A BNP level >1000 pg/ml has clinical importance in primary care medicine and hospital settings. © The Author(s) 2015.

  11. Genesis of the 1000-foot Arecibo dish

    NASA Astrophysics Data System (ADS)

    Cohen, Marshall H.

    2009-07-01

    The giant radar/radio astronomy dish near Arecibo, Puerto Rico, was conceived by William E. Gordon in early 1958 as a back-scattering radar system to measure the density and temperature of the Earth's ionosphere up to a few thousand kilometers. Gordon calculated the required size of the antenna by using the Thomson cross-section for scattering by the electrons, and assuming that the elementary scattered waves would be incoherent. During the summer and autumn of 1958 Gordon led a study group that published a design report in December 1958. The report showed that a dish 1000 feet in diameter would be required, and described a limestone sinkhole in Puerto Rico that would make a suitable support for such a dish. Meanwhile, in November 1958, Kenneth L. Bowles performed an ionospheric radar experiment that showed that the Gordon calculation for the scattered power was roughly correct, but that the calculated spectral width was too big. The consequence of these results was that a dish substantially smaller than 1000 feet could have satisfied the original goals for the radar. However, from the spring of 1958 the value of 1000 feet had been in the minds of the study team, and a large suite of important experiments that such a dish could do had been identified. These apparently became the raison d'être for the project, and the possibility of shrinking the dish to accomplish only the original goals seems to have been ignored. The project was sold to a new federal funding agency, the Advanced Research Projects Agency (ARPA), which was interested, in part at least, because ballistic missiles traveled through the ionosphere and it was important to fully understand that environment. Gordon's original calculation contained a remarkably beneficial error. Without it, it is doubtful that such a large dish would have been built.

  12. 24 CFR Appendix B to Part 1000 - IHBG Block Grant Formula Mechanisms

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false IHBG Block Grant Formula Mechanisms... URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES Pt. 1000, App. B Appendix B to Part 1000—IHBG Block Grant Formula Mechanisms 1. The Indian Housing Block Grant (IHBG) formula consists of two components...

  13. 46 CFR 153.1000 - Special operating requirements for cargoes reactive with water.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Special operating requirements for cargoes reactive with water. 153.1000 Section 153.1000 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Operations Special Cargo Procedures §...

  14. 46 CFR 153.1000 - Special operating requirements for cargoes reactive with water.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Special operating requirements for cargoes reactive with water. 153.1000 Section 153.1000 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Operations Special Cargo Procedures §...

  15. Scalable synthesis and post-modification of a mesoporous metal-organic framework called NU-1000

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Timothy C.; Vermeulen, Nicolaas A.; Kim, In Soo

    The synthesis of NU-1000, a mesoporous metal-organic framework (MOF), can be conducted efficiently on a multigram scale from inexpensive starting materials. NU-1000 has been reported as an excellent candidate for gas separation and catalysis. In particular, it is ideal for the catalytic deactivation of nerve agents and shows great promise as a new generic platform for a wide range of applications. Multiple post-synthetic modification protocols have been developed using NU-1000 as the parent material, making it a potentially useful scaffold for several catalytic applications. The procedure for the preparation of NU-1000 can be scaled up reliably, and it is suitablemore » for the production of 50 g of the tetracarboxylic acid containing organic linker and 200 mg–2.5 g of NU-1000. Lastly, the entire synthesis is performed without purification by column chromatography and can be completed within 10 d.« less

  16. Scalable synthesis and post-modification of a mesoporous metal-organic framework called NU-1000

    DOE PAGES

    Wang, Timothy C.; Vermeulen, Nicolaas A.; Kim, In Soo; ...

    2015-12-17

    The synthesis of NU-1000, a mesoporous metal-organic framework (MOF), can be conducted efficiently on a multigram scale from inexpensive starting materials. NU-1000 has been reported as an excellent candidate for gas separation and catalysis. In particular, it is ideal for the catalytic deactivation of nerve agents and shows great promise as a new generic platform for a wide range of applications. Multiple post-synthetic modification protocols have been developed using NU-1000 as the parent material, making it a potentially useful scaffold for several catalytic applications. The procedure for the preparation of NU-1000 can be scaled up reliably, and it is suitablemore » for the production of 50 g of the tetracarboxylic acid containing organic linker and 200 mg–2.5 g of NU-1000. Lastly, the entire synthesis is performed without purification by column chromatography and can be completed within 10 d.« less

  17. PEGylated DX-1000: pharmacokinetics and antineoplastic activity of a specific plasmin inhibitor.

    PubMed

    Devy, Laetitia; Rabbani, Shafaat A; Stochl, Mark; Ruskowski, Mary; Mackie, Ian; Naa, Laurent; Toews, Mark; van Gool, Reinoud; Chen, Jie; Ley, Art; Ladner, Robert C; Dransfield, Daniel T; Henderikx, Paula

    2007-11-01

    Novel inhibitors of the urokinase-mediated plasminogen (plg) activation system are potentially of great clinical benefit as anticancer treatments. Using phage display, we identified DX-1000 a tissue factor pathway inhibitor-derived Kunitz domain protein which is a specific high-affinity inhibitor of plasmin (pln) (K(i) = 99 pM). When tested in vitro, DX-1000 blocks plasmin-mediated pro-matrix metalloproteinase-9 (proMMP-9) activation on cells and dose-dependently inhibits tube formation, while not significantly affecting hemostasis and coagulation. However, this low-molecular weight protein inhibitor ( approximately 7 kDa) exhibits rapid plasma clearance in mice and rabbits, limiting its potential clinical use in chronic diseases. After site-specific PEGylation, DX-1000 retains its activity and exhibits a decreased plasma clearance. This PEGylated derivative is effective in vitro, as well as potent in inhibiting tumor growth of green fluorescent protein (GFP)-labeled MDA-MB-231 cells. 4PEG-DX-1000 treatment causes a significant reduction of urokinase-type plasminogen activator (uPA) and plasminogen expressions, a reduction of tumor proliferation, and vascularization. 4PEG-DX-1000 treatment significantly decreases the level of active mitogen-activated protein kinase (MAPK) in the primary tumors and reduces metastasis incidence. Together, our results demonstrate the potential value of plasmin inhibitors as therapeutic agents for blocking breast cancer growth and metastasis.

  18. 25 CFR 1000.223 - When can a Tribe/Consortium request a waiver of a regulation?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... regulation? 1000.223 Section 1000.223 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.223 When can a Tribe/Consortium...

  19. 25 CFR 1000.52 - What criteria will the Director use to award advance planning grants?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... planning grants? 1000.52 Section 1000.52 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... INDIAN SELF-DETERMINATION AND EDUCATION ACT Section 402(d) Planning and Negotiation Grants Advance Planning Grant Funding § 1000.52 What criteria will the Director use to award advance planning grants...

  20. 25 CFR 1000.166 - What are the phases of the negotiation process?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false What are the phases of the negotiation process? 1000.166...-DETERMINATION AND EDUCATION ACT Negotiation Process for Annual Funding Agreements Negotiation of Initial Annual Funding Agreements § 1000.166 What are the phases of the negotiation process? There are two phases of the...

  1. 25 CFR 1000.166 - What are the phases of the negotiation process?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false What are the phases of the negotiation process? 1000.166...-DETERMINATION AND EDUCATION ACT Negotiation Process for Annual Funding Agreements Negotiation of Initial Annual Funding Agreements § 1000.166 What are the phases of the negotiation process? There are two phases of the...

  2. 25 CFR 1000.166 - What are the phases of the negotiation process?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What are the phases of the negotiation process? 1000.166...-DETERMINATION AND EDUCATION ACT Negotiation Process for Annual Funding Agreements Negotiation of Initial Annual Funding Agreements § 1000.166 What are the phases of the negotiation process? There are two phases of the...

  3. 25 CFR 1000.166 - What are the phases of the negotiation process?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false What are the phases of the negotiation process? 1000.166...-DETERMINATION AND EDUCATION ACT Negotiation Process for Annual Funding Agreements Negotiation of Initial Annual Funding Agreements § 1000.166 What are the phases of the negotiation process? There are two phases of the...

  4. 25 CFR 1000.166 - What are the phases of the negotiation process?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false What are the phases of the negotiation process? 1000.166...-DETERMINATION AND EDUCATION ACT Negotiation Process for Annual Funding Agreements Negotiation of Initial Annual Funding Agreements § 1000.166 What are the phases of the negotiation process? There are two phases of the...

  5. 25 CFR 1000.400 - Can a Tribe/Consortium retain savings from programs?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false Can a Tribe/Consortium retain savings from programs? 1000...-DETERMINATION AND EDUCATION ACT Miscellaneous Provisions § 1000.400 Can a Tribe/Consortium retain savings from programs? Yes, for BIA programs, the Tribe/Consortium may retain savings for each fiscal year during which...

  6. 25 CFR 1000.392 - How does the Freedom of Information Act apply?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false How does the Freedom of Information Act apply? 1000.392...-DETERMINATION AND EDUCATION ACT Miscellaneous Provisions § 1000.392 How does the Freedom of Information Act apply? (a) Access to records maintained by the Secretary is governed by the Freedom of Information Act...

  7. 25 CFR 1000.162 - What is included in a self-governance compact?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What is included in a self-governance compact? 1000.162...-DETERMINATION AND EDUCATION ACT Negotiation Process for Annual Funding Agreements Negotiating A Self-Governance Compact § 1000.162 What is included in a self-governance compact? A model format for self-governance...

  8. Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.

    PubMed

    de Vries, Paul S; Sabater-Lleal, Maria; Chasman, Daniel I; Trompet, Stella; Ahluwalia, Tarunveer S; Teumer, Alexander; Kleber, Marcus E; Chen, Ming-Huei; Wang, Jie Jin; Attia, John R; Marioni, Riccardo E; Steri, Maristella; Weng, Lu-Chen; Pool, Rene; Grossmann, Vera; Brody, Jennifer A; Venturini, Cristina; Tanaka, Toshiko; Rose, Lynda M; Oldmeadow, Christopher; Mazur, Johanna; Basu, Saonli; Frånberg, Mattias; Yang, Qiong; Ligthart, Symen; Hottenga, Jouke J; Rumley, Ann; Mulas, Antonella; de Craen, Anton J M; Grotevendt, Anne; Taylor, Kent D; Delgado, Graciela E; Kifley, Annette; Lopez, Lorna M; Berentzen, Tina L; Mangino, Massimo; Bandinelli, Stefania; Morrison, Alanna C; Hamsten, Anders; Tofler, Geoffrey; de Maat, Moniek P M; Draisma, Harmen H M; Lowe, Gordon D; Zoledziewska, Magdalena; Sattar, Naveed; Lackner, Karl J; Völker, Uwe; McKnight, Barbara; Huang, Jie; Holliday, Elizabeth G; McEvoy, Mark A; Starr, John M; Hysi, Pirro G; Hernandez, Dena G; Guan, Weihua; Rivadeneira, Fernando; McArdle, Wendy L; Slagboom, P Eline; Zeller, Tanja; Psaty, Bruce M; Uitterlinden, André G; de Geus, Eco J C; Stott, David J; Binder, Harald; Hofman, Albert; Franco, Oscar H; Rotter, Jerome I; Ferrucci, Luigi; Spector, Tim D; Deary, Ian J; März, Winfried; Greinacher, Andreas; Wild, Philipp S; Cucca, Francesco; Boomsma, Dorret I; Watkins, Hugh; Tang, Weihong; Ridker, Paul M; Jukema, Jan W; Scott, Rodney J; Mitchell, Paul; Hansen, Torben; O'Donnell, Christopher J; Smith, Nicholas L; Strachan, David P; Dehghan, Abbas

    2017-01-01

    An increasing number of genome-wide association (GWA) studies are now using the higher resolution 1000 Genomes Project reference panel (1000G) for imputation, with the expectation that 1000G imputation will lead to the discovery of additional associated loci when compared to HapMap imputation. In order to assess the improvement of 1000G over HapMap imputation in identifying associated loci, we compared the results of GWA studies of circulating fibrinogen based on the two reference panels. Using both HapMap and 1000G imputation we performed a meta-analysis of 22 studies comprising the same 91,953 individuals. We identified six additional signals using 1000G imputation, while 29 loci were associated using both HapMap and 1000G imputation. One locus identified using HapMap imputation was not significant using 1000G imputation. The genome-wide significance threshold of 5×10-8 is based on the number of independent statistical tests using HapMap imputation, and 1000G imputation may lead to further independent tests that should be corrected for. When using a stricter Bonferroni correction for the 1000G GWA study (P-value < 2.5×10-8), the number of loci significant only using HapMap imputation increased to 4 while the number of loci significant only using 1000G decreased to 5. In conclusion, 1000G imputation enabled the identification of 20% more loci than HapMap imputation, although the advantage of 1000G imputation became less clear when a stricter Bonferroni correction was used. More generally, our results provide insights that are applicable to the implementation of other dense reference panels that are under development.

  9. Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

    PubMed Central

    de Vries, Paul S.; Sabater-Lleal, Maria; Chasman, Daniel I.; Trompet, Stella; Kleber, Marcus E.; Chen, Ming-Huei; Wang, Jie Jin; Attia, John R.; Marioni, Riccardo E.; Weng, Lu-Chen; Grossmann, Vera; Brody, Jennifer A.; Venturini, Cristina; Tanaka, Toshiko; Rose, Lynda M.; Oldmeadow, Christopher; Mazur, Johanna; Basu, Saonli; Yang, Qiong; Ligthart, Symen; Hottenga, Jouke J.; Rumley, Ann; Mulas, Antonella; de Craen, Anton J. M.; Grotevendt, Anne; Taylor, Kent D.; Delgado, Graciela E.; Kifley, Annette; Lopez, Lorna M.; Berentzen, Tina L.; Mangino, Massimo; Bandinelli, Stefania; Morrison, Alanna C.; Hamsten, Anders; Tofler, Geoffrey; de Maat, Moniek P. M.; Draisma, Harmen H. M.; Lowe, Gordon D.; Zoledziewska, Magdalena; Sattar, Naveed; Lackner, Karl J.; Völker, Uwe; McKnight, Barbara; Huang, Jie; Holliday, Elizabeth G.; McEvoy, Mark A.; Starr, John M.; Hysi, Pirro G.; Hernandez, Dena G.; Guan, Weihua; Rivadeneira, Fernando; McArdle, Wendy L.; Slagboom, P. Eline; Zeller, Tanja; Psaty, Bruce M.; Uitterlinden, André G.; de Geus, Eco J. C.; Stott, David J.; Binder, Harald; Hofman, Albert; Franco, Oscar H.; Rotter, Jerome I.; Ferrucci, Luigi; Spector, Tim D.; Deary, Ian J.; März, Winfried; Greinacher, Andreas; Wild, Philipp S.; Cucca, Francesco; Boomsma, Dorret I.; Watkins, Hugh; Tang, Weihong; Ridker, Paul M.; Jukema, Jan W.; Scott, Rodney J.; Mitchell, Paul; Hansen, Torben; O'Donnell, Christopher J.; Smith, Nicholas L.; Strachan, David P.

    2017-01-01

    An increasing number of genome-wide association (GWA) studies are now using the higher resolution 1000 Genomes Project reference panel (1000G) for imputation, with the expectation that 1000G imputation will lead to the discovery of additional associated loci when compared to HapMap imputation. In order to assess the improvement of 1000G over HapMap imputation in identifying associated loci, we compared the results of GWA studies of circulating fibrinogen based on the two reference panels. Using both HapMap and 1000G imputation we performed a meta-analysis of 22 studies comprising the same 91,953 individuals. We identified six additional signals using 1000G imputation, while 29 loci were associated using both HapMap and 1000G imputation. One locus identified using HapMap imputation was not significant using 1000G imputation. The genome-wide significance threshold of 5×10−8 is based on the number of independent statistical tests using HapMap imputation, and 1000G imputation may lead to further independent tests that should be corrected for. When using a stricter Bonferroni correction for the 1000G GWA study (P-value < 2.5×10−8), the number of loci significant only using HapMap imputation increased to 4 while the number of loci significant only using 1000G decreased to 5. In conclusion, 1000G imputation enabled the identification of 20% more loci than HapMap imputation, although the advantage of 1000G imputation became less clear when a stricter Bonferroni correction was used. More generally, our results provide insights that are applicable to the implementation of other dense reference panels that are under development. PMID:28107422

  10. 25 CFR 1000.222 - How does a Tribe/Consortium obtain a waiver?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false How does a Tribe/Consortium obtain a waiver? 1000.222...-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.222 How does a Tribe/Consortium obtain a waiver? To obtain a waiver, the Tribe/Consortium must: (a) Submit a written request from the designated Tribal...

  11. 25 CFR 1000.333 - How does a Tribe/Consortium retrocede a program?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false How does a Tribe/Consortium retrocede a program? 1000.333...-DETERMINATION AND EDUCATION ACT Retrocession § 1000.333 How does a Tribe/Consortium retrocede a program? The Tribe/Consortium must submit: (a) A written notice to: (1) The Office of Self-Governance for BIA...

  12. 25 CFR 1000.333 - How does a Tribe/Consortium retrocede a program?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false How does a Tribe/Consortium retrocede a program? 1000.333...-DETERMINATION AND EDUCATION ACT Retrocession § 1000.333 How does a Tribe/Consortium retrocede a program? The Tribe/Consortium must submit: (a) A written notice to: (1) The Office of Self-Governance for BIA...

  13. 49 CFR 232.207 - Class IA brake tests-1,000-mile inspection.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Class IA brake tests-1,000-mile inspection. 232... Class IA brake tests—1,000-mile inspection. (a) Except as provided in § 232.213, each train shall receive a Class IA brake test performed by a qualified person, as defined in § 232.5, at a location that...

  14. 49 CFR 232.207 - Class IA brake tests-1,000-mile inspection.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Class IA brake tests-1,000-mile inspection. 232... Class IA brake tests—1,000-mile inspection. (a) Except as provided in § 232.213, each train shall receive a Class IA brake test performed by a qualified person, as defined in § 232.5, at a location that...

  15. 40 CFR 158.1000 - Applicator exposure-general requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Human Exposure § 158.1000 Applicator exposure—general... Occupational Safety and Health Administration (OSHA), provide adequate protection from risk under FIFRA for a particular pesticide use pattern, exposure data may not be required for that use pattern. Applicants should...

  16. 40 CFR 158.1000 - Applicator exposure-general requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Human Exposure § 158.1000 Applicator exposure—general... Occupational Safety and Health Administration (OSHA), provide adequate protection from risk under FIFRA for a particular pesticide use pattern, exposure data may not be required for that use pattern. Applicants should...

  17. 40 CFR 158.1000 - Applicator exposure-general requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Human Exposure § 158.1000 Applicator exposure—general... Occupational Safety and Health Administration (OSHA), provide adequate protection from risk under FIFRA for a particular pesticide use pattern, exposure data may not be required for that use pattern. Applicants should...

  18. 40 CFR 158.1000 - Applicator exposure-general requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Human Exposure § 158.1000 Applicator exposure—general... Occupational Safety and Health Administration (OSHA), provide adequate protection from risk under FIFRA for a particular pesticide use pattern, exposure data may not be required for that use pattern. Applicants should...

  19. 40 CFR 158.1000 - Applicator exposure-general requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Human Exposure § 158.1000 Applicator exposure—general... Occupational Safety and Health Administration (OSHA), provide adequate protection from risk under FIFRA for a particular pesticide use pattern, exposure data may not be required for that use pattern. Applicants should...

  20. Submillimeter Spectroscopy with a 500-1000 GHz SIS Receiver

    NASA Technical Reports Server (NTRS)

    Zmuidzinas, J.

    1997-01-01

    Sub-millimeter Spectroscopy with a 500-1000 GHz SIS Receiver, which extended over the period October 1, 1991 through January 31, 1997. The purpose of the grant was to fund the development and construction of a sensitive heterodyne receiver system for the submillimeter band (500-1000 GHz), using our newly-developed sensitive superconducting (SIS) detectors, and to carry out astronomical observations with this system aboard the NASA Kuiper Air- borne Observatory (a Lockheed C-141 aircraft carrying a 91 cm telescope). A secondary purpose of the grant was to stimulate the continued development of sensitive submillimeter detectors, in order to prepare for the next-generation airborne observatory, SOFIA, as well as future space missions (such as the ESA/NASA FIRST mission).

  1. Usefulness of 1000-Hz probe tone in tympanometry according to age in Korean infants.

    PubMed

    Park, Mina; Han, Kyu-Hee; Jung, Hyunseo; Kim, Mee-Hee; Chang, Hyun-Kyung; Kim, Shin Hye; Park, Moo Kyun; Lee, Jun Ho

    2015-01-01

    Numerous studies have shown the superiority of a 1000-Hz frequency probe tone for evaluating the middle ear status of infants. However, most of these studies examined Caucasian populations. This study validated the 1000-Hz probe tone and evaluated the age at which it should be used in Korean infants. Data from 83 infants (43 males, 40 females; mean age 9.2±6.2 (range 1-30) months, 165 ears) were analyzed. Tympanograms were classified according to Baldwin's modification of the method of Marchant et al. and correlated with results based on combined diagnostic tests, including an endoscopic examination of the tympanic membrane, myringotomy findings, and the air and bone conduction auditory brainstem response (ABR) thresholds. Data were analyzed in five age groups, each covering a 3-month range. The traces were measured for both 226- and 1000-Hz probe tones. The sensitivity and specificity for the different age groups were also determined. For the 226-Hz probe tone, the tympanograms showed normal traces for most ears with otitis media effusions in infants younger than 12 months. By contrast, the tympanograms using the 1000-Hz probe tone showed abnormal traces in most of the infants with otitis media effusions in all age groups. In infants with no otitis media effusion, the tympanograms using both 226- and 1000-Hz probe tones were interpreted as normal in most cases in all age groups. In infants younger than 12 months, the sensitivity of the 226-Hz probe tone was very low (0-6.6%), whereas that of the 1000-Hz probe tone was very high (90-100%). In infants older than 13 months, however, the sensitivities of the 226- and 1000-Hz probe tones were 76.2% and 85.7%, respectively. Regarding specificity, the difference between the two probe tones was not significant for any age group. This study confirmed the superiority of the 1000-Hz probe tone for evaluating the middle ear in infants. We recommend using a 1000-Hz probe tone at least up to the age of 12 months for Korean

  2. 25 CFR 1000.225 - Are meetings or discussions mandatory?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.225 Are meetings or discussions mandatory? No, a meeting with the...

  3. Acoustic reflex on newborns: the influence of the 226 and 1,000 Hz probes.

    PubMed

    Jacob-Corteletti, Lilian Cássia Bórnia; Duarte, Josilene Luciene; Zucki, Fernanda; Mariotto, Luciane Domingues Figueiredo; Lauris, José Roberto Pereira; Alvarenga, Kátia de Freitas

    2015-01-01

    To analyze the occurrence of acoustic reflex and its threshold on newborns using the 226 and 1,000 Hz probes. Thirty-six newborns with "PASS" results in newborn hearing screening and tympanogram with one or two peaks for both probe tones were included. Group I comprised 20 full-term newborns without risk indicator for hearing loss, and Group II comprised 16 newborns with at least one risk indicator. The study about ipsilateral acoustic reflex thresholds was conducted in 500, 1,000, 2,000, and 4,000 Hz. The groups presented the acoustic reflex thresholds between 50 and 100 dB for both probe tones. In the comparison between the probes, there were differences in all frequencies evaluated in Group I, with the lowest threshold mean for the 1,000 Hz probe. In Group II, differences were detected at 2,000 Hz. The mean acoustic reflex thresholds were similar in both groups for the 226 Hz probe. There was a difference for the 1,000 Hz probe in all tested frequencies. The percentage of response was higher in both groups for the 1,000 Hz probe. The kappa test showed extremely poor agreement in the comparison of results between both probes. The occurrence of acoustic reflex was higher in newborns and its thresholds were lower with the 1,000 Hz probe both for healthy newborns and for newborns at risk.

  4. Comparison of 1000-Centistoke versus 5000-Centistoke Silicone Oil in Complex Retinal Detachment Surgery.

    PubMed

    Zafar, Shakir; Shakir, Munira; Mahmood, Syed Asaad; Amin, Saima; Iqbal, Zafar

    2016-01-01

    To compare the efficacy and complications of using 1000-centistoke versus 5000-centistoke silicone oil for complex retinal detachment repair. Case series. LRBT Tertiary Eye Hospital, Karachi, from January 2007 to June 2013. Eighty-five eyes (85 patients) presenting with superior rhegmatogenous retinal detachments associated with PVR grades B and C (involving not more than 3 clock hours) were randomized to either 1000 centistokes (n=44) or 5000 centistokes (n=41) silicone oil group. All patients underwent 23-gauge pars plana vitrectomy surgery with silicone oil intraocular tamponade. Patient data was analysed at 18 months post-operatively. IBM SPSS 21 was used for data analysis. There were 52 male and 33 female patients aged between 22 and 70 years (45.2 ±16.2). After the first surgery, successful reattachment of the retina was achieved in 67 eyes (78.8%); of which 35 eyes were in 1000-centistoke and 32 eyes in 5000-centistoke groups. Mean pre-operative Best Corrected Visual Acuity (BCVA) was 1.63 ±0.54 which was improved to a mean post-operative BCVAof 1.46 ±0.78 (1.42 ±0.74 in 1000-centistoke group; 1.49 ±0.78 in 5000 centistoke group). The 1000-centistoke group had a significantly higher frequency of oil emulsification which necessitated early removal of silicone oil. There were 66 eyes (77%) with at least one complication (34 eyes in 1000-centistoke group; 32 eyes in 5000-centistoke group) including cataract, corneal abnormalities, raised IOP, hypotony, vitreous haemorrhage and retinal redetachment. Although visual and anatomical outcomes were comparable between the two groups, the 1000-centistoke silicone oil group developed early oil emulsification necessitating its early removal.

  5. 76 FR 82079 - AP1000 Design Certification Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ... reference Revision 15 of the design control document (DCD) (ADAMS Accession No. ML053460400), which... to DAC in the areas of piping design (Chapter 3), instrumentation and control (I&C) systems (Chapter... Systems Manual, as described in the AP1000 Design Control Document, Revision 17, meets the criteria of...

  6. 24 CFR 1000.1 - What is the applicability and scope of these regulations?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What is the applicability and scope of these regulations? 1000.1 Section 1000.1 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN HOUSING...

  7. Heat capacity and entropy of Ni2SiO4-olivine from 5 to 1000 K and heat capacity of Co2SiO4 from 360 to 1000 K.

    USGS Publications Warehouse

    Robie, R.A.; Hemingway, B.S.; Ito, J.; Krupka, K.M.

    1984-01-01

    The heat capacity of Ni2SiO4-olivine has been measured between 5 and 387 K by cryogenic adiabatic-shield calorimetry and between 360 and 1000 K by differential scanning calorimetry. The heat capacity of Co2SiO4-olivine was measured between 360 and 1000 K by differential scanning calorimetry.-J.A.Z.

  8. Navy DDG-1000 (DD(X)) and CG(X) Programs: Background and Issues for Congress

    DTIC Science & Technology

    2006-06-20

    Report RL32665, Navy Force Structure and Shipbuilding Plans : Background and Issues for Congress, by Ronald O’Rourke. The Navy wants to procure a total of 7...DDG-1000s and 19 CG(X)s as part of a proposed 313-ship fleet.2 Under the Navy’s proposed plan , the first two DDG-1000s are to be procured in FY2007...major DDG-1000 contractors, including Northrop Grumman’s Ship Systems ( NGSS ) division (which includes the Ingalls Shipyard in Pascagoula, MS), General

  9. 25 CFR 1000.15 - How many additional Tribes/Consortia may participate in self-governance per year?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false How many additional Tribes/Consortia may participate in self-governance per year? 1000.15 Section 1000.15 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN... Participation in Tribal Self-Governance Eligibility § 1000.15 How many additional Tribes/Consortia may...

  10. 25 CFR 1000.365 - What are the requirements of the review team report?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false What are the requirements of the review team report? 1000.365 Section 1000.365 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE... requirements of the review team report? A report summarizing the results of the trust evaluation will be...

  11. 25 CFR 1000.365 - What are the requirements of the review team report?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false What are the requirements of the review team report? 1000.365 Section 1000.365 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE... requirements of the review team report? A report summarizing the results of the trust evaluation will be...

  12. 25 CFR 1000.365 - What are the requirements of the review team report?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false What are the requirements of the review team report? 1000.365 Section 1000.365 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE... requirements of the review team report? A report summarizing the results of the trust evaluation will be...

  13. 25 CFR 1000.365 - What are the requirements of the review team report?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false What are the requirements of the review team report? 1000.365 Section 1000.365 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE... requirements of the review team report? A report summarizing the results of the trust evaluation will be...

  14. 25 CFR 1000.365 - What are the requirements of the review team report?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What are the requirements of the review team report? 1000.365 Section 1000.365 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE... requirements of the review team report? A report summarizing the results of the trust evaluation will be...

  15. The miR-1000-p53 pathway regulates apoptosis and virus infection in shrimp.

    PubMed

    Gong, Yi; Ju, Chenyu; Zhang, Xiaobo

    2015-10-01

    The p53 protein plays an important role in apoptosis which is involved in the immunity of animals. However, effects of the miRNA-mediated regulation of p53 expression on apoptosis and virus infection are not extensively investigated. To address this issue, the miRNA-mediated p53-dependent apoptotic pathway was explored in this study. The results indicated that p53 could regulate the apoptotic activity of Marsupenaeus japonicas shrimp and influence the infection of white spot syndrome virus (WSSV). The further data presented that miR-1000 could target the 3'-untranslated region (3'UTR) of p53 gene. The results of in vivo experiments showed that the miR-1000 overexpression led to significant decreases of shrimp apoptotic activity and the capacity of WSSV infection, while the miR-1000 silencing resulted in significant increases of apoptotic activity and virus infection, indicating that miR-1000 took great effects on apoptosis and virus infection by targeting p53. Therefore, our study revealed a novel mechanism that the miR-1000-p53 pathway regulated apoptosis and virus infection in shrimp. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. 24 CFR 1000.44 - What prohibitions on the use of debarred, suspended, or ineligible contractors apply?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What prohibitions on the use of debarred, suspended, or ineligible contractors apply? 1000.44 Section 1000.44 Housing and Urban Development... § 1000.44 What prohibitions on the use of debarred, suspended, or ineligible contractors apply? In...

  17. Thorough analysis of unorthodox ABO deletions called by the 1000 Genomes project.

    PubMed

    Möller, M; Hellberg, Å; Olsson, M L

    2018-02-01

    ABO remains the clinically most important blood group system, but despite earlier extensive research, significant findings are still being made. The vast majority of catalogued ABO null alleles are based on the c.261delG polymorphism. Apart from c.802G>A, other mechanisms for O alleles are rare. While analysing the data set from the 1000 Genomes (1000G) project, we encountered two previously uncharacterized deletions, which needed further exploration. The Erythrogene database, complemented with bioinformatics software, was used to analyse ABO in 2504 individuals from 1000G. DNA samples from selected 1000G donors and African blood donors were examined by allele-specific PCR and Sanger sequencing to characterize predicted deletions. A 5821-bp deletion encompassing exons 5-7 was called in twenty 1000G individuals, predominantly Africans. This allele was confirmed and its exact deletion point defined by bioinformatic analyses and in vitro experiments. A PCR assay was developed, and screening of African samples revealed three donors heterozygous for this deletion, which was thereby phenotypically established as an O allele. Analysis of upstream genetic markers indicated an ancestral origin from ABO*O.01.02. We estimate this deletion as the 3rd most common mechanism behind O alleles. A 24-bp deletion was called in nine individuals and showed greater diversity regarding ethnic distribution and allelic background. It could neither be confirmed by in silico nor in vitro experiments. A previously uncharacterized ABO deletion among Africans was comprehensively mapped and a genotyping strategy devised. The false prediction of another deletion emphasizes the need for cautious interpretation of NGS data and calls for strict validation routines. © 2017 International Society of Blood Transfusion.

  18. 25 CFR 1000.302 - “What is imminent jeopardy” to a trust asset?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .../or Federal law while performing trust functions if the disregard creates such an immediate threat. ... 25 Indians 2 2010-04-01 2010-04-01 false âWhat is imminent jeopardyâ to a trust asset? 1000.302...-DETERMINATION AND EDUCATION ACT Reassumption § 1000.302 “What is imminent jeopardy” to a trust asset? Imminent...

  19. Carbon Nanostructure of Kraft Lignin Thermally Treated at 500 to 1000 °C.

    PubMed

    Zhang, Xuefeng; Yan, Qiangu; Leng, Weiqi; Li, Jinghao; Zhang, Jilei; Cai, Zhiyong; Hassan, El Barbary

    2017-08-21

    Kraft lignin (KL) was thermally treated at 500 to 1000 °C in an inert atmosphere. Carbon nanostructure parameters of thermally treated KL in terms of amorphous carbon fraction, aromaticity, and carbon nanocrystallites lateral size ( L a ), thickness ( L c ), and interlayer space ( d 002 ) were analyzed quantitatively using X-ray diffraction, Raman spectroscopy, and high-resolution transmission electron microscopy. Experimental results indicated that increasing temperature reduced amorphous carbon but increased aromaticity in thermally treated KL materials. The L c value of thermally treated KL materials averaged 0.85 nm and did not change with temperature. The d 002 value decreased from 3.56 Å at 500 °C to 3.49 Å at 1000 °C. The L a value increased from 0.7 to 1.4 nm as temperature increased from 500 to 1000 °C. A nanostructure model was proposed to describe thermally treated KL under 1000 °C. The thermal stability of heat treated KL increased with temperature rising from 500 to 800 °C.

  20. A comparison of cataloged variation between International HapMap Consortium and 1000 Genomes Project data.

    PubMed

    Buchanan, Carrie C; Torstenson, Eric S; Bush, William S; Ritchie, Marylyn D

    2012-01-01

    Since publication of the human genome in 2003, geneticists have been interested in risk variant associations to resolve the etiology of traits and complex diseases. The International HapMap Consortium undertook an effort to catalog all common variation across the genome (variants with a minor allele frequency (MAF) of at least 5% in one or more ethnic groups). HapMap along with advances in genotyping technology led to genome-wide association studies which have identified common variants associated with many traits and diseases. In 2008 the 1000 Genomes Project aimed to sequence 2500 individuals and identify rare variants and 99% of variants with a MAF of <1%. To determine whether the 1000 Genomes Project includes all the variants in HapMap, we examined the overlap between single nucleotide polymorphisms (SNPs) genotyped in the two resources using merged phase II/III HapMap data and low coverage pilot data from 1000 Genomes. Comparison of the two data sets showed that approximately 72% of HapMap SNPs were also found in 1000 Genomes Project pilot data. After filtering out HapMap variants with a MAF of <5% (separately for each population), 99% of HapMap SNPs were found in 1000 Genomes data. Not all variants cataloged in HapMap are also cataloged in 1000 Genomes. This could affect decisions about which resource to use for SNP queries, rare variant validation, or imputation. Both the HapMap and 1000 Genomes Project databases are useful resources for human genetics, but it is important to understand the assumptions made and filtering strategies employed by these projects.

  1. 25 CFR 1000.171 - When should a Tribe/Consortium submit a letter of interest?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... interest? 1000.171 Section 1000.171 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Negotiation Process for Annual Funding Agreements Negotiation...

  2. Pacing Behavior and Tactical Positioning in 500- and 1000-m Short-Track Speed Skating.

    PubMed

    Noorbergen, Olaf S; Konings, Marco J; Micklewright, Dominic; Elferink-Gemser, Marije T; Hettinga, Florentina J

    2016-09-01

    To explore pacing behavior and tactical positioning during the shorter 500- and 1000-m short-track competitions. Lap times and intermediate rankings of elite 500- and 1000-m short-track-skating competitors were collected over the 2012-13 season. First, lap times were analyzed using a MANOVA, and for each lap, differences between sex, race type, final ranking, and stage of competition were determined. Second, Kendall tau-b correlations were used to assess relationships between intermediate and final rankings. In addition, intermediate rankings of the winner of each race were examined. Top-placed athletes appeared faster than bottom-placed athletes in every lap in the 500-m, while in the 1000-m no differences were found until the final 4 laps (P < .05). Correlations between intermediate and final rankings were already high at the beginning stages of the 50-m (lap 1: r = .59) but not for the 1000-m (lap 1: r = .21). Although 500- and 1000-m short-track races are both relatively short, fundamental differences in pacing behavior and tactical positioning were found. A fast-start strategy seems to be optimal for 500-m races, while the crucial segment in 1000-m races seems to be from the 6th lap to the finish line (ie, after ± 650 m). These findings provide evidence to suggest that athletes balance between choosing an energetically optimal profile and the tactical and positional benefits that play a role when riding against an opponent, as well as contributing to developing novel insights in exploring athletic behavior when racing against opponents.

  3. Alignment of 1000 Genomes Project reads to reference assembly GRCh38.

    PubMed

    Zheng-Bradley, Xiangqun; Streeter, Ian; Fairley, Susan; Richardson, David; Clarke, Laura; Flicek, Paul

    2017-07-01

    The 1000 Genomes Project produced more than 100 trillion basepairs of short read sequence from more than 2600 samples in 26 populations over a period of five years. In its final phase, the project released over 85 million genotyped and phased variants on human reference genome assembly GRCh37. An updated reference assembly, GRCh38, was released in late 2013, but there was insufficient time for the final phase of the project analysis to change to the new assembly. Although it is possible to lift the coordinates of the 1000 Genomes Project variants to the new assembly, this is a potentially error-prone process as coordinate remapping is most appropriate only for non-repetitive regions of the genome and those that did not see significant change between the two assemblies. It will also miss variants in any region that was newly added to GRCh38. Thus, to produce the highest quality variants and genotypes on GRCh38, the best strategy is to realign the reads and recall the variants based on the new alignment. As the first step of variant calling for the 1000 Genomes Project data, we have finished remapping all of the 1000 Genomes sequence reads to GRCh38 with alternative scaffold-aware BWA-MEM. The resulting alignments are available as CRAM, a reference-based sequence compression format. The data have been released on our FTP site and are also available from European Nucleotide Archive to facilitate researchers discovering variants on the primary sequences and alternative contigs of GRCh38. © The Authors 2017. Published by Oxford University Press.

  4. Scalable synthesis and post-modification of a mesoporous metal-organic framework called NU-1000

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Timothy C.; Vermeulen, Nicolaas A.; Kim, In Soo

    The synthesis of NU-1000, a highly robust mesoporous (containing pores >2 nm) metal-organic framework (MOF), can be conducted efficiently on a multigram scale from inexpensive starting materials. Tetrabromopyrene and (4-(ethoxycarbonyl)phenyl)boronic acid can easily be coupled to prepare the requisite organic strut with four metal-binding sites in the form of four carboxylic acids, while zirconyl chloride octahydrate is used as a precursor for the well-defined metal oxide clusters. NU-1000 has been reported as an excellent candidate for the separation of gases, and it is a versatile scaffold for heterogeneous catalysis. In particular, it is ideal for the catalytic deactivation of nervemore » agents, and it shows great promise as a new generic platform for a wide range of applications. Multiple post-synthetic modification protocols have been developed using NU-1000 as the parent material, making it a potentially useful scaffold for several catalytic applications. The procedure for the preparation of NU-1000 can be scaled up reliably, and it is suitable for the production of 50 g of the tetracarboxylic acid containing organic linker and 200 mg–2.5 g of NU-1000. The entire synthesis is performed without purification by column chromatography and can be completed within 10 d.« less

  5. Scalable synthesis and post-modification of a mesoporous metal-organic framework called NU-1000.

    PubMed

    Wang, Timothy C; Vermeulen, Nicolaas A; Kim, In Soo; Martinson, Alex B F; Stoddart, J Fraser; Hupp, Joseph T; Farha, Omar K

    2016-01-01

    The synthesis of NU-1000, a highly robust mesoporous (containing pores >2 nm) metal-organic framework (MOF), can be conducted efficiently on a multigram scale from inexpensive starting materials. Tetrabromopyrene and (4-(ethoxycarbonyl)phenyl)boronic acid can easily be coupled to prepare the requisite organic strut with four metal-binding sites in the form of four carboxylic acids, while zirconyl chloride octahydrate is used as a precursor for the well-defined metal oxide clusters. NU-1000 has been reported as an excellent candidate for the separation of gases, and it is a versatile scaffold for heterogeneous catalysis. In particular, it is ideal for the catalytic deactivation of nerve agents, and it shows great promise as a new generic platform for a wide range of applications. Multiple post-synthetic modification protocols have been developed using NU-1000 as the parent material, making it a potentially useful scaffold for several catalytic applications. The procedure for the preparation of NU-1000 can be scaled up reliably, and it is suitable for the production of 50 g of the tetracarboxylic acid containing organic linker and 200 mg-2.5 g of NU-1000. The entire synthesis is performed without purification by column chromatography and can be completed within 10 d.

  6. Role of a Modulator in the Synthesis of Phase-Pure NU-1000.

    PubMed

    Webber, Thomas E; Liu, Wei-Guang; Desai, Sai Puneet; Lu, Connie C; Truhlar, Donald G; Penn, R Lee

    2017-11-15

    NU-1000 is a robust, mesoporous metal-organic framework (MOF) with hexazirconium nodes ([Zr 6 O 16 H 16 ] 8+ , referred to as oxo-Zr 6 nodes) that can be synthesized by combining a solution of ZrOCl 2 ·8H 2 O and a benzoic acid modulator in N,N-dimethylformamide with a solution of linker (1,3,6,8-tetrakis(p-benzoic acid)pyrene, referred to as H 4 TBAPy) and by aging at an elevated temperature. Typically, the resulting crystals are primarily composed of NU-1000 domains that crystallize with a more dense phase that shares structural similarity with NU-901, which is an MOF composed of the same linker molecules and nodes. Density differences between the two polymorphs arise from the differences in the node orientation: in NU-1000, the oxo-Zr 6 nodes rotate 120° from node to node, whereas in NU-901, all nodes are aligned in parallel. Considering this structural difference leads to the hypothesis that changing the modulator from benzoic acid to a larger and more rigid biphenyl-4-carboxylic acid might lead to a stronger steric interaction between the modulator coordinating on the oxo-Zr 6 node and misaligned nodes or linkers in the large pore and inhibit the growth of the more dense NU-901-like material, resulting in phase-pure NU-1000. Side-by-side reactions comparing the products of synthesis using benzoic acid or biphenyl-4-carboxylic acid as a modulator produce structurally heterogeneous crystals and phase-pure NU-1000 crystals. It can be concluded that the larger and more rigid biphenyl-4-carboxylate inhibits the incorporation of nodes with an alignment parallel to the neighboring nodes already residing in the crystal.

  7. Production Facility Prototype Blower 1000 Hour Test Results II

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wass, Alexander Joseph; Woloshun, Keith Albert; Dale, Gregory E.

    Long duration tests of the Aerzen GM 12.4 roots style blower in a closed loop configuration provides valuable data and lessons learned for long-term operation at the Mo-99 production facility. The blower was operated in a closed loop configuration with the flow conditions anticipated in plant operation with a Mo-100 target inline. The additional thermal energy generated from beam heating of the Mo-100 disks were not included in these tests. Five 1000 hour tests have been completed since the first test was performed in January of 2016. All five 1000 hour tests have proven successful in exposing preventable issues relatedmore » to oil and helium leaks. All blower tests to this date have resulted in stable blower performance and consistency. A summary of the results for each test, including a review of the first and second tests, are included in this report.« less

  8. 38 CFR 17.1000 - Payment or reimbursement for emergency services for nonservice-connected conditions in non-VA...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... for emergency services for nonservice-connected conditions in non-VA facilities. 17.1000 Section 17.1000 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Payment Or Reimbursement for Emergency Services for Nonservice-Connected Conditions in Non-Va Facilities § 17.1000 Payment...

  9. A comparison of cataloged variation between International HapMap Consortium and 1000 Genomes Project data

    PubMed Central

    Buchanan, Carrie C; Torstenson, Eric S; Bush, William S

    2012-01-01

    Background Since publication of the human genome in 2003, geneticists have been interested in risk variant associations to resolve the etiology of traits and complex diseases. The International HapMap Consortium undertook an effort to catalog all common variation across the genome (variants with a minor allele frequency (MAF) of at least 5% in one or more ethnic groups). HapMap along with advances in genotyping technology led to genome-wide association studies which have identified common variants associated with many traits and diseases. In 2008 the 1000 Genomes Project aimed to sequence 2500 individuals and identify rare variants and 99% of variants with a MAF of <1%. Methods To determine whether the 1000 Genomes Project includes all the variants in HapMap, we examined the overlap between single nucleotide polymorphisms (SNPs) genotyped in the two resources using merged phase II/III HapMap data and low coverage pilot data from 1000 Genomes. Results Comparison of the two data sets showed that approximately 72% of HapMap SNPs were also found in 1000 Genomes Project pilot data. After filtering out HapMap variants with a MAF of <5% (separately for each population), 99% of HapMap SNPs were found in 1000 Genomes data. Conclusions Not all variants cataloged in HapMap are also cataloged in 1000 Genomes. This could affect decisions about which resource to use for SNP queries, rare variant validation, or imputation. Both the HapMap and 1000 Genomes Project databases are useful resources for human genetics, but it is important to understand the assumptions made and filtering strategies employed by these projects. PMID:22319179

  10. 25 CFR 1000.224 - How can a Tribe/Consortium expedite the review of a regulation waiver request?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... regulation waiver request? 1000.224 Section 1000.224 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.224 How can a...

  11. 25 CFR 1000.396 - Does a Tribe/Consortium have additional ongoing requirements to maintain minimum standards for...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false Does a Tribe/Consortium have additional ongoing requirements to maintain minimum standards for Tribe/Consortium management systems? 1000.396 Section 1000.396... Miscellaneous Provisions § 1000.396 Does a Tribe/Consortium have additional ongoing requirements to maintain...

  12. 25 CFR 1000.359 - What are the responsibilities of the Secretary's designated representative(s) after the annual...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... designated representative(s) after the annual trust evaluation? 1000.359 Section 1000.359 Indians OFFICE OF... THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Trust Evaluation Review Annual Trust Evaluations § 1000.359 What are the responsibilities of the Secretary's...

  13. 25 CFR 1000.361 - Will the annual review include a review of the Secretary's residual trust functions?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...'s residual trust functions? 1000.361 Section 1000.361 Indians OFFICE OF THE ASSISTANT SECRETARY... AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Trust Evaluation Review Annual Trust Evaluations § 1000.361 Will the annual review include a review of the Secretary's residual trust functions...

  14. 24 CFR 1000.242 - When does the requirement for exemption from taxation apply to affordable housing activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... exemption from taxation apply to affordable housing activities? 1000.242 Section 1000.242 Housing and Urban... ACTIVITIES Indian Housing Plan (IHP) § 1000.242 When does the requirement for exemption from taxation apply to affordable housing activities? The requirement for exemption from taxation applies only to rental...

  15. 24 CFR 1000.242 - When does the requirement for exemption from taxation apply to affordable housing activities?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... exemption from taxation apply to affordable housing activities? 1000.242 Section 1000.242 Housing and Urban... ACTIVITIES Indian Housing Plan (IHP) § 1000.242 When does the requirement for exemption from taxation apply to affordable housing activities? The requirement for exemption from taxation applies only to rental...

  16. Comparison of older adults' steps per day using NL-1000 pedometer and two GT3X+ accelerometer filters.

    PubMed

    Barreira, Tiago V; Brouillette, Robert M; Foil, Heather C; Keller, Jeffrey N; Tudor-Locke, Catrine

    2013-10-01

    The purpose of this study was to compare the steps/d derived from the ActiGraph GT3X+ using the manufacturer's default filter (DF) and low-frequency-extension filter (LFX) with those from the NL-1000 pedometer in an older adult sample. Fifteen older adults (61-82 yr) wore a GT3X+ (24 hr/day) and an NL-1000 (waking hours) for 7 d. Day was the unit of analysis (n = 86 valid days) comparing (a) GT3X+ DF and NL-1000 steps/d and (b) GT3X+ LFX and NL-1000 steps/d. DF was highly correlated with NL-1000 (r = .80), but there was a significant mean difference (-769 steps/d). LFX and NL-1000 were highly correlated (r = .90), but there also was a significant mean difference (8,140 steps/d). Percent difference and absolute percent difference between DF and NL-1000 were -7.4% and 16.0%, respectively, and for LFX and NL-1000 both were 121.9%. Regardless of filter used, GT3X+ did not provide comparable pedometer estimates of steps/d in this older adult sample.

  17. 25 CFR 1000.357 - May the parties negotiate standards of review for purposes of the trust evaluation?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... purposes of the trust evaluation? 1000.357 Section 1000.357 Indians OFFICE OF THE ASSISTANT SECRETARY... AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Trust Evaluation Review Annual Trust Evaluations § 1000.357 May the parties negotiate standards of review for purposes of the trust evaluation? Yes...

  18. 25 CFR 1000.136 - When will this determination be made?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... EDUCATION ACT Non-BIA Annual Self-Governance Compacts and Funding Agreements Eligibility § 1000.136 When will this determination be made? It will occur during the pre-negotiation process, subject to the...

  19. AP1000{sup R} nuclear power plant safety overview for spent fuel cooling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gorgemans, J.; Mulhollem, L.; Glavin, J.

    2012-07-01

    The AP1000{sup R} plant is an 1100-MWe class pressurized water reactor with passive safety features and extensive plant simplifications that enhance construction, operation, maintenance, safety and costs. The AP1000 design uses passive features to mitigate design basis accidents. The passive safety systems are designed to function without safety-grade support systems such as AC power, component cooling water, service water or HVAC. Furthermore, these passive features 'fail safe' during a non-LOCA event such that DC power and instrumentation are not required. The AP1000 also has simple, active, defense-in-depth systems to support normal plant operations. These active systems provide the first levelmore » of defense against more probable events and they provide investment protection, reduce the demands on the passive features and support the probabilistic risk assessment. The AP1000 passive safety approach allows the plant to achieve and maintain safe shutdown in case of an accident for 72 hours without operator action, meeting the expectations provided in the U.S. Utility Requirement Document and the European Utility Requirements for passive plants. Limited operator actions are required to maintain safe conditions in the spent fuel pool via passive means. In line with the AP1000 approach to safety described above, the AP1000 plant design features multiple, diverse lines of defense to ensure spent fuel cooling can be maintained for design-basis events and beyond design-basis accidents. During normal and abnormal conditions, defense-in-depth and other systems provide highly reliable spent fuel pool cooling. They rely on off-site AC power or the on-site standby diesel generators. For unlikely design basis events with an extended loss of AC power (i.e., station blackout) or loss of heat sink or both, spent fuel cooling can still be provided indefinitely: - Passive systems, requiring minimal or no operator actions, are sufficient for at least 72 hours under all

  20. Calculating moisture content for 1000-hour timelag fuels in western Washington and western Oregon.

    Treesearch

    Roger D. Ottmar; David V. Sandberg

    1985-01-01

    A predictive model is presented to calculate moisture content of 1000-hour timelag fuels in Douglas-fir (Pseudotsuga menziesii (Mirb.) Franco) and western hemlock (Tsuga heterophylla (Raf.) Sarg.) logging slash in western Washington and western Oregon. The model is a modification of the 1000-hour fuel moisture model of the...

  1. 25 CFR 1000.278 - Does this coverage extend to subcontractors of self-governance AFAs?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Does this coverage extend to subcontractors of self-governance AFAs? 1000.278 Section 1000.278 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... subcontractors of self-governance AFAs? No, subcontractors or subgrantees providing services to a Pub. L. 93-638...

  2. 24 CFR 1000.110 - Under what conditions may non low-income Indian families participate in the program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Under what conditions may non low-income Indian families participate in the program? 1000.110 Section 1000.110 Housing and Urban... ACTIVITIES Affordable Housing Activities § 1000.110 Under what conditions may non low-income Indian families...

  3. 25 CFR 1000.367 - Will the Department evaluate a Tribe's/Consortium's performance of non-trust related programs?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Evaluations § 1000.367 Will the Department evaluate a Tribe's/Consortium's performance of non-trust related... 25 Indians 2 2010-04-01 2010-04-01 false Will the Department evaluate a Tribe's/Consortium's performance of non-trust related programs? 1000.367 Section 1000.367 Indians OFFICE OF THE ASSISTANT SECRETARY...

  4. 16 CFR § 1000.29 - Directorate for Engineering Sciences.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Directorate for Engineering Sciences. Â... ORGANIZATION AND FUNCTIONS § 1000.29 Directorate for Engineering Sciences. The Directorate for Engineering Sciences, which is managed by the Associate Executive Director for Engineering Sciences, is responsible for...

  5. 25 CFR 1000.21 - When does a Tribe/Consortium have a “material audit exception”?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...-Governance Eligibility § 1000.21 When does a Tribe/Consortium have a “material audit exception”? A Tribe/Consortium has a material audit exception if any of the audits that it submitted under § 1000.17(c...

  6. 40 CFR 721.1000 - Benzenamine, 3-chloro-2,6-dinitro-N,N-dipropyl-4-(tri-fluoro-methyl)-.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Benzenamine, 3-chloro-2,6-dinitro-N,N-dipropyl-4-(tri-fluoro-methyl)-. 721.1000 Section 721.1000 Protection of Environment ENVIRONMENTAL... Significant New Uses for Specific Chemical Substances § 721.1000 Benzenamine, 3-chloro-2,6-dinitro-N,N...

  7. 25 CFR 1000.318 - When will the Secretary return management of a reassumed program?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... management of a reassumed program? A reassumed program may be included in future AFAs, but the Secretary may... 25 Indians 2 2014-04-01 2014-04-01 false When will the Secretary return management of a reassumed program? 1000.318 Section 1000.318 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT...

  8. 25 CFR 1000.318 - When will the Secretary return management of a reassumed program?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... management of a reassumed program? A reassumed program may be included in future AFAs, but the Secretary may... 25 Indians 2 2013-04-01 2013-04-01 false When will the Secretary return management of a reassumed program? 1000.318 Section 1000.318 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT...

  9. 25 CFR 1000.318 - When will the Secretary return management of a reassumed program?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... management of a reassumed program? A reassumed program may be included in future AFAs, but the Secretary may... 25 Indians 2 2011-04-01 2011-04-01 false When will the Secretary return management of a reassumed program? 1000.318 Section 1000.318 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT...

  10. 25 CFR 1000.318 - When will the Secretary return management of a reassumed program?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... management of a reassumed program? A reassumed program may be included in future AFAs, but the Secretary may... 25 Indians 2 2012-04-01 2012-04-01 false When will the Secretary return management of a reassumed program? 1000.318 Section 1000.318 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT...

  11. 25 CFR 1000.318 - When will the Secretary return management of a reassumed program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... management of a reassumed program? A reassumed program may be included in future AFAs, but the Secretary may... 25 Indians 2 2010-04-01 2010-04-01 false When will the Secretary return management of a reassumed program? 1000.318 Section 1000.318 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT...

  12. Preparation macroconstants to simulate the core of VVER-1000 reactor

    NASA Astrophysics Data System (ADS)

    Seleznev, V. Y.

    2017-01-01

    Dynamic model is used in simulators of VVER-1000 reactor for training of operating staff and students. As a code for the simulation of neutron-physical characteristics is used DYNCO code that allows you to perform calculations of stationary, transient and emergency processes in real time to a different geometry of the reactor lattices [1]. To perform calculations using this code, you need to prepare macroconstants for each FA. One way of getting macroconstants is to use the WIMS code, which is based on the use of its own 69-group macroconstants library. This paper presents the results of calculations of FA obtained by the WIMS code for VVER-1000 reactor with different parameters of fuel and coolant, as well as the method of selection of energy groups for further calculation macroconstants.

  13. SCIENCE Magazine: BATSE 1000 gamma-ray burst perspective

    NASA Technical Reports Server (NTRS)

    Horack, John M.

    1995-01-01

    A historical highlight and analysis of the Burst and Transient Source Experiment (BATSE), which has been in operation for more than three years and has detected more than 1,000 cosmic gamma-ray bursts is presented. The questions BATSE has answered and those it has not are assessed, along with the problems and data correlation and processing that has occured from the BATSE operation.

  14. 16. LOOKING SOUTHEAST AT THE LINDE 1000 TONS PER DAY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. LOOKING SOUTHEAST AT THE LINDE 1000 TONS PER DAY HIGH PURITY OXYGEN MAKING PLANT SHOWING THE TWIN OXYGEN FRACTIONATING TOWERS. - U.S. Steel Duquesne Works, Fuel & Utilities Plant, Along Monongahela River, Duquesne, Allegheny County, PA

  15. All-cause mortality in asymptomatic persons with extensive Agatston scores above 1000.

    PubMed

    Patel, Jaideep; Blaha, Michael J; McEvoy, John W; Qadir, Sadia; Tota-Maharaj, Rajesh; Shaw, Leslee J; Rumberger, John A; Callister, Tracy Q; Berman, Daniel S; Min, James K; Raggi, Paolo; Agatston, Arthur A; Blumenthal, Roger S; Budoff, Matthew J; Nasir, Khurram

    2014-01-01

    Risk assessment in the extensive calcified plaque phenotype has been limited by small sample size. We studied all-cause mortality rates among asymptomatic patients with markedly elevated Agatston scores > 1000. We studied a clinical cohort of 44,052 asymptomatic patients referred for coronary calcium scans. Mean follow-up was 5.6 years (range, 1-13 years). All-cause mortality rates were calculated after stratifying by Agatston score (0, 1-1000, 1001-1500, 1500-2000, and >2000). A multivariable Cox regression model adjusting for self-reported traditional risk factors was created to assess the relative mortality hazard of Agatston scores 1001 to 1500, 1501 to 2000, and >2000. With the use of post-estimation modeling, we assessed for the presence of an upper threshold of risk with high Agatston scores. A total of 1593 patients (4% of total population) had Agatston score > 1000. There was a continuous graded decrease in estimated 10-year survival across increasing Agatston score, continuing when Agatston score > 1000 (Agatston score 1001-1500, 78%; Agatston score 1501-2000, 74%; Agatston score > 2000, 51%). After multivariable adjustment, Agatston scores 1001 to 1500, 1501 to 2000, and >2000 were associated with an 8.05-, 7.45-, and 13.26-fold greater mortality risk, respectively, than for Agatston score of 0. Compared with Agatston score 1001 to 1500, Agatston score 1501 to 2000 had a similar all-cause mortality risk, whereas Agatston score > 2000 had an increased relative risk (Agatston score 1501-2000: hazard ratio [HR], 1.01 [95% CI, 0.67-1.51]; Agatston score > 2000: HR, 1.79 [95% CI, 1.30-2.46]). Graphical assessment of the predicted survival model suggests no upper threshold for risk associated with calcified plaque in coronary arteries. Increasing calcified plaque in coronary arteries continues to predict a graded decrease in survival among patients with extensive Agatston score > 1000 with no apparent upper threshold. Published by Elsevier Inc.

  16. 25 CFR 1000.464 - What personal conflicts of interest must the standards of conduct regulate?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... conduct regulate? 1000.464 Section 1000.464 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... interest must the standards of conduct regulate? The personal conflicts of interest standards must: (a... financial interest or an employment relationship; (b) Prohibit such officers, employees, or agents from...

  17. 17. NORTHWEST VIEW OF LINDE 1000 TONS PER DAY HIGH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. NORTHWEST VIEW OF LINDE 1000 TONS PER DAY HIGH PURITY OXYGEN MAKING PLANT SHOWING FRACTIONATING TOWER, NITROGEN REGENERATORS, AND REVERSING HEAT EXCHANGERS. - U.S. Steel Duquesne Works, Fuel & Utilities Plant, Along Monongahela River, Duquesne, Allegheny County, PA

  18. 16 CFR 1000.8 - Meetings and hearings; public notice.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... FUNCTIONS § 1000.8 Meetings and hearings; public notice. (a) The Commission may meet and exercise all its... agency, including the rendering of official decisions, are generally announced in advance and open to the... appropriate to its functions anywhere in the United States. It will publish a notice of any proposed hearing...

  19. [Investigation of tympanogram in newborns with 226 hz and 1000 hz probe tones].

    PubMed

    Li, Mengyin; Zheng, Yun; Li, Gang; Wang, Kai

    2012-11-01

    This study aims at investigating tympanogram in newborns who passed hearing screening using 226 and 1 000 Hz probe tones in order to interpret the test results correctly and find out its clinical value in audiological evaluation and diagnosis in this population. Tympanogram was conducted using 226 and 1000 Hz probe tones in 206 newborns between 2 and 7 days of age (3.92 +/- 1.24) in both ears that passed the DPOAE screening and without any of the high risk register (HRR) factors associated with hearing loss according to the Joint Committee on Infant Hearing in 2007. The tympanogram results tested in 408 ear were as following: the percentage of single-peaked, double-peaked, and none-peaked tympanograms using 226 Hz were 52.20% (213 ears), 47.55% (194 ears) and 0.25% (1 ear) respectively. The percentage of single-peaked and other morphological type tympanograms using 1000 Hz were 94.85%(387 ears) and 5.15% (21 ears) respectively. The parameters of 1000 Hz single-peaked tympanogram in this study were as following: the average tympanometric peak pressure was 33.24 +/- 44.37 dapa, the average peak compensated static acoustic admittance was 0.52 +/- 0.25 mmho, the average tympanometric width for right and left ears were 121.38 +/- 28.79 and 108.63 +/- 26.00 dapa respectively with a statistically significant difference between them (P < 0.01). The average volume of ear canal (Vec, using 226 Hz probe tone) at boys and girls were 0.44 +/- 0.10 and 0.43 +/- 0.08 ml respectively with a statistically significant difference between them (P < 0.05). The morphology of tympanogram using a 226 Hz probe tone in newborns usually includes two main types: single-peaked and double-peaked, while it is primarily the single-peaked tympanogram while using a 1000 Hz probe tone. It is more appropriate to use a 1000 Hz probe tone than 226 Hz when testing newborns' tympanogram. The parameters obtained in this study using 1000 Hz and 226 Hz could be tried and applied to interpret clinical

  20. ANDalyze Lead 100 Test Kit and AND1000 Fluorimeter Environmental Technology Verification Report and Statement

    EPA Science Inventory

    This report provides results for the verification testing of the Lead100/AND1000. The following is a description of the technology based on information provided by the vendor. The information provided below was not verified in this test. The ANDalyze Lead100/AND1000 was des...

  1. 25 CFR 1000.335 - How will retrocession affect the Tribe's/Consortium's existing and future AFAs?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... existing and future AFAs? 1000.335 Section 1000.335 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT... affect the Tribe's/Consortium's existing and future AFAs? Retrocession does not affect other parts of the...

  2. 25 CFR 1000.335 - How will retrocession affect the Tribe's/Consortium's existing and future AFAs?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... existing and future AFAs? 1000.335 Section 1000.335 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT... affect the Tribe's/Consortium's existing and future AFAs? Retrocession does not affect other parts of the...

  3. 25 CFR 1000.335 - How will retrocession affect the Tribe's/Consortium's existing and future AFAs?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... existing and future AFAs? 1000.335 Section 1000.335 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT... affect the Tribe's/Consortium's existing and future AFAs? Retrocession does not affect other parts of the...

  4. 25 CFR 1000.335 - How will retrocession affect the Tribe's/Consortium's existing and future AFAs?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... existing and future AFAs? 1000.335 Section 1000.335 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT... affect the Tribe's/Consortium's existing and future AFAs? Retrocession does not affect other parts of the...

  5. 25 CFR 1000.335 - How will retrocession affect the Tribe's/Consortium's existing and future AFAs?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... existing and future AFAs? 1000.335 Section 1000.335 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT... affect the Tribe's/Consortium's existing and future AFAs? Retrocession does not affect other parts of the...

  6. 25 CFR 1000.382 - What may the Tribe's/Consortium's annual report on self-governance address?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...-governance address? 1000.382 Section 1000.382 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... report on self-governance address? (a) The Tribe's/Consortium's annual self-governance report may address... the programs and services funded under self-governance, summarized and annotated as the Tribe may deem...

  7. Investigation of mutations in the HBB gene using the 1,000 genomes database.

    PubMed

    Carlice-Dos-Reis, Tânia; Viana, Jaime; Moreira, Fabiano Cordeiro; Cardoso, Greice de Lemos; Guerreiro, João; Santos, Sidney; Ribeiro-Dos-Santos, Ândrea

    2017-01-01

    Mutations in the HBB gene are responsible for several serious hemoglobinopathies, such as sickle cell anemia and β-thalassemia. Sickle cell anemia is one of the most common monogenic diseases worldwide. Due to its prevalence, diverse strategies have been developed for a better understanding of its molecular mechanisms. In silico analysis has been increasingly used to investigate the genotype-phenotype relationship of many diseases, and the sequences of healthy individuals deposited in the 1,000 Genomes database appear to be an excellent tool for such analysis. The objective of this study is to analyze the variations in the HBB gene in the 1,000 Genomes database, to describe the mutation frequencies in the different population groups, and to investigate the pattern of pathogenicity. The computational tool SNPEFF was used to align the data from 2,504 samples of the 1,000 Genomes database with the HG19 genome reference. The pathogenicity of each amino acid change was investigated using the databases CLINVAR, dbSNP and HbVar and five different predictors. Twenty different mutations were found in 209 healthy individuals. The African group had the highest number of individuals with mutations, and the European group had the lowest number. Thus, it is concluded that approximately 8.3% of phenotypically healthy individuals from the 1,000 Genomes database have some mutation in the HBB gene. The frequency of mutated genes was estimated at 0.042, so that the expected frequency of being homozygous or compound heterozygous for these variants in the next generation is approximately 0.002. In total, 193 subjects had a non-synonymous mutation, which 186 (7.4%) have a deleterious mutation. Considering that the 1,000 Genomes database is representative of the world's population, it can be estimated that fourteen out of every 10,000 individuals in the world will have a hemoglobinopathy in the next generation.

  8. 24 CFR 1000.120 - May a recipient use Indian preference or tribal preference in selecting families for housing...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false May a recipient use Indian preference or tribal preference in selecting families for housing assistance? 1000.120 Section 1000.120... AMERICAN HOUSING ACTIVITIES Affordable Housing Activities § 1000.120 May a recipient use Indian preference...

  9. 25 CFR 1000.61 - Are other funds available to self-governance Tribes/Consortia for planning and negotiating with...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .../Consortia for planning and negotiating with non-BIA bureaus? 1000.61 Section 1000.61 Indians OFFICE OF THE... SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Other Financial Assistance for Planning and Negotiation Grants for Non-BIA Programs Purpose and Eligibility § 1000.61 Are...

  10. Report of 1,000 Hour Catalyst Longevity Evaluation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Daniel M. Ginosar

    2009-06-01

    This report presents the results of a 1,000 hour, high-pressure, catalyst longevity test for the decomposition of concentrated sulfuric acid. The reaction is used for both the sulfur-iodine (S-I) cycle and hybrid sulfur cycle. By the time of the delivery date of April 17, 2009, for project milestone no. 2NIN07TC050114, the 1% Pt/TiO2 catalyst had been in the reaction environment for 658 hours. During the first 480 hours of testing, the catalyst activity provided stable, near-equilibrium yields of 46.8% SO2 and 22.8% O2. However, product yields declined at sample exposure times >480 hours. At 658 hours of operation, catalyst activitymore » (based on oxygen yield) declined to 57% relative to the stable period of catalyst activity. Thus, as of April 17, this catalyst did not provide the desired stability level of <10% degradation per 1,000 hours. The experiment was terminated on April 27, after 792 hours, when a fitting failed and the catalyst was displaced from the reactor such that the sample could not be recovered. Oxygen conversion at the end of the experiment was 12.5% and declining, suggesting that at that point, catalyst activity had decreased to 54% of the initial level.« less

  11. Long term spectral irradiance measurements of a 1000-watt xenon arc lamp

    NASA Technical Reports Server (NTRS)

    Schneider, W. E.

    1974-01-01

    Spectral irradiance measurements over the range of 200 to 1060 nm were made on a 1000-watt xenon arc lamp over a period of 1500 hours. Four sets of measurements were made after periods of 70, 525, 1000, and 1500 hours of operation. The lamp (Hanovia Compact Xenon Arc Lamp) was mounted in the NASA Solar Irradiation System. When used in the System, the lamp is used as the radiating source for six test stations. Measurements were made of both the longterm stability (or variation of spectral irradiance as a function of time) and the actual spectral irradiance incident on the test specimen.

  12. The thermal expansion of anhydrite to 1000° C

    USGS Publications Warehouse

    Evans, Howard T.

    1979-01-01

    The thermal expansion of anhydrite, CaSO4, has been measured from 22° to 1,000° C by X-ray diffraction, using the Guinier-Lenné heating powder camera. The heating patterns were calibrated with Guinier-Hägg patterns at 25° C, using quartz as internal standard. Heating experiments were run on natural anhydrite (Bancroft, Ontario), which at room temperature has lattice constants in close agreement with those of synthetic material. The orthorhombic unit cell at 22° C (space groupAmma) has a=7.003 (1) Å, b=6.996 (2) Å and c=6.242 (1) Å, V=305.9 (2) Å3. At room temperature, the thermal expansion coefficients α and β (α in °C−1×104, β in °C−2×108) are for a, 0.10, −0.69; forb, 0.08, 0.19; for c, 0.18, 1.60; for V, 0.37, 1.14. Second-order coefficients provide an excellent fit over the whole range to 1,000° C.

  13. 25 CFR 1000.395 - Do OMB circulars and revisions apply to self-governance funding agreements?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Do OMB circulars and revisions apply to self-governance funding agreements? 1000.395 Section 1000.395 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... revisions apply to self-governance funding agreements? Yes, OMB circulars and revisions apply, except for...

  14. 25 CFR 1000.88 - Do Tribes/Consortia need Secretarial approval to redesign BIA programs that the Tribe/Consortium...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false Do Tribes/Consortia need Secretarial approval to redesign BIA programs that the Tribe/Consortium administers under an AFA? 1000.88 Section 1000.88 Indians... in An Afa § 1000.88 Do Tribes/Consortia need Secretarial approval to redesign BIA programs that the...

  15. 24 CFR 1000.238 - What percentage of the IHBG funds can be used for administrative and planning expenses?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What percentage of the IHBG funds can be used for administrative and planning expenses? 1000.238 Section 1000.238 Housing and Urban... ACTIVITIES Indian Housing Plan (IHP) § 1000.238 What percentage of the IHBG funds can be used for...

  16. 47 CFR 17.10 - Antenna structures over 304.80 meters (1,000 feet) in height.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... feet) in height. 17.10 Section 17.10 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL... § 17.10 Antenna structures over 304.80 meters (1,000 feet) in height. Where one or more antenna farm... of an existing station proposing the erection of an antenna structure over 304.80 meters (1,000 feet...

  17. 47 CFR 17.10 - Antenna structures over 304.80 meters (1,000 feet) in height.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... feet) in height. 17.10 Section 17.10 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL... § 17.10 Antenna structures over 304.80 meters (1,000 feet) in height. Where one or more antenna farm... of an existing station proposing the erection of an antenna structure over 304.80 meters (1,000 feet...

  18. 7 CFR 1000.42 - Classification of transfers and diversions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .... (a) Transfers and diversions to pool plants. Skim milk or butterfat transferred or diverted in the form of a fluid milk product or transferred in the form of a bulk fluid cream product from a pool plant... corresponding step of § 1000.44(b); (2) If the transferring plant received during the month other source milk to...

  19. Multiple recycle of REMIX fuel at VVER-1000 operation in closed fuel cycle

    NASA Astrophysics Data System (ADS)

    Alekseev, P. N.; Bobrov, E. A.; Chibinyaev, A. V.; Teplov, P. S.; Dudnikov, A. A.

    2015-12-01

    The basic features of loading the VVER-1000 core with a new variant of REMIX fuel (REgenerated MIXture of U-Pu oxides) are considered during its multiple recycle in a closed nuclear fuel cycle. The fuel composition is produced on the basis of the uranium-plutonium regenerate extracted at processing the spent nuclear fuel (SNF) from a VVER-1000, depleted uranium, and the fissionable material: 235U as a part of highly enriched uranium (HEU) from warheads superfluous for defense purposes or 233U accumulated in thorium blankets of fusion (electronuclear) neutron sources or fast reactors. Production of such a fuel assumes no use of natural uranium in addition. When converting a part of the VVER-1000 reactors to the closed fuel cycle based on the REMIX technology, the consumption of natural uranium decreases considerably, and there is no substantial degradation of the isotopic composition of plutonium or change in the reactor-safety characteristics at the passage from recycle to recycle.

  20. 30 CFR 77.1000 - Highwalls, pits and spoil banks; plans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... safe working conditions. The mining methods employed by the operator shall be selected to insure... Section 77.1000 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND...

  1. 16 CFR 1000.23 - Office of Information and Technology Services.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., budget, information management and work tracking; administration of the network, telephone systems, and... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Office of Information and Technology... COMMISSION ORGANIZATION AND FUNCTIONS § 1000.23 Office of Information and Technology Services. The Office of...

  2. 16 CFR 1000.23 - Office of Information and Technology Services.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., budget, information management and work tracking; administration of the network, telephone systems, and... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Office of Information and Technology... COMMISSION ORGANIZATION AND FUNCTIONS § 1000.23 Office of Information and Technology Services. The Office of...

  3. 16 CFR 1000.23 - Office of Information and Technology Services.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., budget, information management and work tracking; administration of the network, telephone systems, and... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Office of Information and Technology... COMMISSION ORGANIZATION AND FUNCTIONS § 1000.23 Office of Information and Technology Services. The Office of...

  4. 29 CFR 780.1000 - Scope and significance of interpretative bulletin.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... STANDARDS ACT Employment of Home- workers in Making Wreaths; Exemption From Minimum Wage, Overtime... minimum wage, overtime pay, and child labor provisions of the Act for certain homeworkers employed in... Section 780.1000 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF...

  5. 16 CFR 1000.23 - Office of Information and Technology Services.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Office of Information and Technology... COMMISSION ORGANIZATION AND FUNCTIONS § 1000.23 Office of Information and Technology Services. The Office of Information and Technology Services houses the Commission's Secretariat, which facilitates the preparation of...

  6. 25 CFR 1000.66 - What must be included in the application?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... EDUCATION ACT Other Financial Assistance for Planning and Negotiation Grants for Non-BIA Programs Eligibility and Application Process § 1000.66 What must be included in the application? The application for a...

  7. 25 CFR 1000.66 - What must be included in the application?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... EDUCATION ACT Other Financial Assistance for Planning and Negotiation Grants for Non-BIA Programs Eligibility and Application Process § 1000.66 What must be included in the application? The application for a...

  8. 25 CFR 1000.66 - What must be included in the application?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... EDUCATION ACT Other Financial Assistance for Planning and Negotiation Grants for Non-BIA Programs Eligibility and Application Process § 1000.66 What must be included in the application? The application for a...

  9. 25 CFR 1000.66 - What must be included in the application?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... EDUCATION ACT Other Financial Assistance for Planning and Negotiation Grants for Non-BIA Programs Eligibility and Application Process § 1000.66 What must be included in the application? The application for a...

  10. Operation of the WWR-S Reactor in Poland and in the Period 1961-1962; DOKLAD OB ISPOL'ZOVANII I EKSPLUATATSII REAKTORA TIPA VVR-C V POL'SHE ZA 1961-1962 GODA

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aleksandrowicz, J.

    1963-03-01

    The experimental equipment used in the work at the horizontal reactor channels is listed. Diagrams of the utilization of the nominal reactor power and core loading are given, the reactivity fractions of the separate fuel assemblies are detonated, together with the diagram of reactivity versus burnup. Reactor channels and space used for sample irradiation and isotope production are described, and the total number of irradiations is given. Results of the measurements connected with the routine reactor operation are quoted, namely: analysis of water purity in the primary circuit, analysis of the work of the ion exchanger and mechanical filter, andmore » analysis of air activity in the special ventilation system. Data are given concerning radiation protection of personnel, including individual monitoring. Leak testing of the fuel elements is discussed. Damage of the reactor equipment and appearance of alarm signals are described. (auth)« less

  11. 25 CFR 1000.173 - How does a newly selected Tribe/Consortium initiate the negotiation phase?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false How does a newly selected Tribe/Consortium initiate the negotiation phase? 1000.173 Section 1000.173 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATIO...

  12. PI-RADS version 2: evaluation of diffusion-weighted imaging interpretation between b = 1000 and b = 1500 s mm-2.

    PubMed

    Kwon, Mi-Ri; Kim, Chan Kyo; Kim, Jae-Hun

    2017-11-01

    To investigate the variability of diffusion-weighted imaging (DWI) interpretation of Prostate Imaging Reporting and Data System (PI-RADS) version 2 (v2) in evaluating prostate cancer (PCa). 154 patients with PCa underwent multiparametric 3T MRI, followed by radical prostatectomy. DWI with different b values (b = 0, 100, 1000 and 1500 s mm - 2 ) was obtained. Using the PI-RADS v2, two radiologists independently scored suspicious lesions in each patient and compared DWI of b = 1000 (DWI 1000 ) with 1500 (DWI 1500 ) s mm - 2 . On DWI 1000 and DWI 1500 , the intermethod and interobserver agreements of DWI scores were excellent in all patients (κ ≥ 0.873). In each peripheral zone and transition zone DWI scores, both observers showed excellent intermethod agreement between DWI 1000 and DWI 1500 (κ ≥ 0.897), and interobserver agreement for DWI 1000 and DWI 1500 was good to excellent (κ ≥ 0.796). For estimating clinically significant cancer, the area under receiver operating characteristics curves of DWI 1000 and DWI 1500 were 0.710 and 0.724 for observer 1 (p = 0.11), and 0.649 and 0.656 for observer 2 (p = 0.12), respectively. The PI-RADS v2 scoring at 3T shows excellent agreement between DWI 1000 and DWI 1500 in evaluating PCa, with excellent inter-observer agreement. Advance in knowledge: DWI using b = 1000 s mm -2 instead of b = 1500 s mm -2 reduces examination time or image distortion, with improved the signal-to-noise ratio.

  13. Linear and Nonlinear Infrasound Propagation to 1000 km

    DTIC Science & Technology

    2015-12-15

    Kirtland AFB, NM 87117-5776 10. SPONSOR/MONITOR’S ACRONYM(S) AFRL /RVBYE 11. SPONSOR/MONITOR’S REPORT NUMBER(S) AFRL -RV-PS-TR-2016-0017 12...distribution is unlimited. 30 DISTRIBUTION LIST DTIC/OCP 8725 John J. Kingman Rd, Suite 0944 Ft Belvoir, VA 22060-6218 1 cy AFRL /RVIL Kirtland ... AFRL -RV-PS- AFRL -RV-PS- TR-2016-0017 TR-2016-0017 LINEAR AND NONLINEAR INFRASOUND PROPAGATION TO 1000 KM Catherine de Groot-Hedlin Scripps

  14. 24 CFR 1000.554 - Which agencies have right of access to the recipient's records relating to activities carried out...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... NATIVE AMERICAN HOUSING ACTIVITIES Recipient Monitoring, Oversight and Accountability § 1000.554 Which agencies have right of access to the recipient's records relating to activities carried out under NAHASDA... to the recipient's records relating to activities carried out under NAHASDA? 1000.554 Section 1000...

  15. 24 CFR 1000.554 - Which agencies have right of access to the recipient's records relating to activities carried out...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... NATIVE AMERICAN HOUSING ACTIVITIES Recipient Monitoring, Oversight and Accountability § 1000.554 Which agencies have right of access to the recipient's records relating to activities carried out under NAHASDA... to the recipient's records relating to activities carried out under NAHASDA? 1000.554 Section 1000...

  16. 24 CFR 1000.554 - Which agencies have right of access to the recipient's records relating to activities carried out...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... NATIVE AMERICAN HOUSING ACTIVITIES Recipient Monitoring, Oversight and Accountability § 1000.554 Which agencies have right of access to the recipient's records relating to activities carried out under NAHASDA... to the recipient's records relating to activities carried out under NAHASDA? 1000.554 Section 1000...

  17. 24 CFR 1000.554 - Which agencies have right of access to the recipient's records relating to activities carried out...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... NATIVE AMERICAN HOUSING ACTIVITIES Recipient Monitoring, Oversight and Accountability § 1000.554 Which agencies have right of access to the recipient's records relating to activities carried out under NAHASDA... to the recipient's records relating to activities carried out under NAHASDA? 1000.554 Section 1000...

  18. 24 CFR 1000.554 - Which agencies have right of access to the recipient's records relating to activities carried out...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... NATIVE AMERICAN HOUSING ACTIVITIES Recipient Monitoring, Oversight and Accountability § 1000.554 Which agencies have right of access to the recipient's records relating to activities carried out under NAHASDA... to the recipient's records relating to activities carried out under NAHASDA? 1000.554 Section 1000...

  19. Risk Factors for Childhood Obesity in the First 1,000 Days: A Systematic Review.

    PubMed

    Woo Baidal, Jennifer A; Locks, Lindsey M; Cheng, Erika R; Blake-Lamb, Tiffany L; Perkins, Meghan E; Taveras, Elsie M

    2016-06-01

    Mounting evidence suggests that the origins of childhood obesity and related disparities can be found as early as the "first 1,000 days"-the period from conception to age 2 years. The main goal of this study is to systematically review existing evidence for modifiable childhood obesity risk factors present from conception to age 2 years. PubMed, Embase, and Web of Science were searched for studies published between January 1, 1980, and December 12, 2014, of childhood obesity risk factors present during the first 1,000 days. Prospective, original human subject, English-language research with exposure occurrence during the first 1,000 days and with the outcome of childhood overweight or obesity (BMI ≥85th percentile for age and sex) collected between age 6 months and 18 years were analyzed between December 13, 2014, and March 15, 2015. Of 5,952 identified citations, 282 studies met inclusion criteria. Several risk factors during the first 1,000 days were consistently associated with later childhood obesity. These included higher maternal pre-pregnancy BMI, prenatal tobacco exposure, maternal excess gestational weight gain, high infant birth weight, and accelerated infant weight gain. Fewer studies also supported gestational diabetes, child care attendance, low strength of maternal-infant relationship, low SES, curtailed infant sleep, inappropriate bottle use, introduction of solid food intake before age 4 months, and infant antibiotic exposure as risk factors for childhood obesity. Modifiable risk factors in the first 1,000 days can inform future research and policy priorities and intervention efforts to prevent childhood obesity. Copyright © 2016 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  20. 30 CFR 77.1000 - Highwalls, pits and spoil banks; plans.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Section 77.1000 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND... developed after June 30, 1971, which shall be consistent with prudent engineering design and will insure...

  1. 30 CFR 77.1000 - Highwalls, pits and spoil banks; plans.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Section 77.1000 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND... developed after June 30, 1971, which shall be consistent with prudent engineering design and will insure...

  2. 30 CFR 77.1000 - Highwalls, pits and spoil banks; plans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Section 77.1000 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND... developed after June 30, 1971, which shall be consistent with prudent engineering design and will insure...

  3. 30 CFR 77.1000 - Highwalls, pits and spoil banks; plans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Section 77.1000 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND... developed after June 30, 1971, which shall be consistent with prudent engineering design and will insure...

  4. 24 CFR 1000.122 - May NAHASDA grant funds be used as matching funds to obtain and leverage funding, including any...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... considered an affordable housing activity? 1000.122 Section 1000.122 Housing and Urban Development... Housing Activities § 1000.122 May NAHASDA grant funds be used as matching funds to obtain and leverage...

  5. 25 CFR 1000.46 - Which Tribes/Consortia may be selected to receive a negotiation grant?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Which Tribes/Consortia may be selected to receive a negotiation grant? 1000.46 Section 1000.46 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT...

  6. 25 CFR 1000.47 - What must a Tribe/Consortium do to receive a negotiation grant?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What must a Tribe/Consortium do to receive a negotiation grant? 1000.47 Section 1000.47 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Section...

  7. 25 CFR 1000.350 - What is the purpose of this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... EDUCATION ACT Trust Evaluation Review § 1000.350 What is the purpose of this subpart? This subpart describes how the trust responsibility of the United States is legally maintained through a system of trust...

  8. 25 CFR 1000.163 - Can a Tribe/Consortium negotiate other terms and conditions not contained in the model compact?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... conditions not contained in the model compact? 1000.163 Section 1000.163 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF... Funding Agreements Negotiating A Self-Governance Compact § 1000.163 Can a Tribe/Consortium negotiate other...

  9. Surface Temperature Reconstructions for the Last 1000 Years

    NASA Astrophysics Data System (ADS)

    North, G. R.

    2006-12-01

    This is a presentation of results from a recently released report written by a committee established by the National Research Council and chaired by the speaker. The report was titled the same as the title of this talk. It focused on the methods of reconstructing the large scales of such surface temperature fields, since there has been considerable discussion in the scientific literature, assessments such as the IPCC, the popular press, blogs and even Congressional Hearings. The so-called `hockey stick' curve indicating a gradual cooling from the beginning of the record at about 1000AD to roughly 150 years ago when the curve take a steep upward trend (the so-called global warming). The original publications by Mann, Bradley and Hughes were careful to present and emphasize error margins that have been ignored by many in the controversy. The Committee found that numerous subsequent publications have reported reconstructions that utilized different data and different statistical assumptions. These all fall within the error margins of the original studies. While the committee has some reservations about the period prior to the year 1600AD, it still concludes that it is plausible that surface temperatures averaged over the Northern Hemisphere over the last three decades are plausibly the warmest for any such comparable period in the last 1000 years.

  10. 24 CFR 1000.124 - What maximum and minimum rent or homebuyer payment can a recipient charge a low-income rental...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... assisted with NAHASDA grant amounts? 1000.124 Section 1000.124 Housing and Urban Development Regulations... Activities § 1000.124 What maximum and minimum rent or homebuyer payment can a recipient charge a low-income...

  11. Severe maternal morbidity and comorbid risk in hospitals performing <1000 deliveries per year.

    PubMed

    Hehir, Mark P; Ananth, Cande V; Wright, Jason D; Siddiq, Zainab; D'Alton, Mary E; Friedman, Alexander M

    2017-02-01

    While research has demonstrated increasing risk for severe maternal morbidity in the United States, risk at lower volume hospitals remains poorly characterized. More than half of all obstetric units in the United States perform <1000 deliveries per year and improving care at these hospitals may be critical to reducing risk nationwide. We sought to characterize maternal risk profiles and severe maternal morbidity at low-volume hospitals in the United States. We used data from the Nationwide Inpatient Sample to evaluate trends in severe maternal morbidity and comorbid risk during delivery hospitalizations in the United States from 1998 through 2011. Comorbid maternal risk was estimated using a comorbidity index validated for obstetric patients. Severe maternal morbidity was defined as the presence of any 1 of 15 diagnoses representative of acute organ injury and critical illness. A total of 2,300,279 deliveries occurred at hospitals with annual delivery volume <1000, representing 20% of delivery hospitalizations overall. There were 7849 cases (0.34%) of severe morbidity in low-volume hospitals and this risk increased over the course of the study from 0.25% in 1998 through 1999 to 0.49% in 2010 through 2011 (P < .01). The risk in hospitals with ≥1000 deliveries increased from 0.35-0.62% during the same time periods. The proportion of patients with the lowest comorbidity decreased, while the proportion of patients with highest comorbidity increased the most. The risk of severe morbidity increased across all women including those with low comorbidity scores. Risk for severe morbidity associated with obstetric hemorrhage, infection, hypertensive diseases of pregnancy, and medical conditions all increased during the study period. Our findings demonstrate increasing maternal risk at hospitals performing <1000 deliveries per year broadly distributed over the patient population. Rates of morbidity in centers with ≥1000 deliveries have also increased. These findings

  12. 24 CFR 1000.108 - How is HUD approval obtained by a recipient for housing for non low-income Indian families and...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... recipient for housing for non low-income Indian families and model activities? 1000.108 Section 1000.108... AMERICAN HOUSING ACTIVITIES Affordable Housing Activities § 1000.108 How is HUD approval obtained by a.... Assistance to non low-income Indian families must be in accordance with § 1000.110. Proposals may be...

  13. 25 CFR 1000.105 - What are self-governance base budgets?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false What are self-governance base budgets? 1000.105 Section... FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Annual Funding Agreements for Bureau of Indian Affairs Programs Establishing Self-Governance...

  14. 25 CFR 1000.105 - What are self-governance base budgets?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false What are self-governance base budgets? 1000.105 Section... FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Annual Funding Agreements for Bureau of Indian Affairs Programs Establishing Self-Governance...

  15. 25 CFR 1000.105 - What are self-governance base budgets?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false What are self-governance base budgets? 1000.105 Section... FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Annual Funding Agreements for Bureau of Indian Affairs Programs Establishing Self-Governance...

  16. 25 CFR 1000.105 - What are self-governance base budgets?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false What are self-governance base budgets? 1000.105 Section... FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Annual Funding Agreements for Bureau of Indian Affairs Programs Establishing Self-Governance...

  17. The Presto 1000: A novel automated transcranial Doppler ultrasound system.

    PubMed

    Han, Seunggu J; Rutledge, William Caleb; Englot, Dario J; Winkler, Ethan A; Browne, Janet L; Pflugrath, Lauren; Cronsier, David; Abla, Adib A; Kliot, Michel; Lawton, Michael T

    2015-11-01

    We examined the reliability and ease of use of a novel automated transcranial Doppler (TCD) system in comparison to a conventional TCD system. TCD ultrasound allows non-invasive monitoring of cerebral blood flow, and can predict arterial vasospasm after a subarachnoid hemorrhage (SAH). The Presto 1000 TCD system (PhysioSonics, Bellevue, WA, USA) is designed for monitoring flow through the M1 segment of the middle cerebral artery (MCA) via temporal windows. The Presto 1000 system was tested across multiple preclinical and clinical settings in parallel with a control predicate TCD system. In a phantom flow generating device, both the Presto 1000 and Spencer system (Spencer Technologies, Redmond, WA, USA) were able to detect velocities with high accuracy. In nine volunteer patients, the Presto system was able to locate the MCA in 14 out of 18 temporal windows, in an average of 12.5s. In the SAH cohort of five patients with a total of 25 paired measurements, the mean absolute difference in flow velocities of the M1 segment, as measured by the two systems, was 17.5 cm/s. These data suggest that the Presto system offers an automated TCD that can reliably localize and detect flow of the MCA, with relative ease of use. The system carries the additional benefit of requiring minimal training for the operator, and can be used by many providers across multiple bedside settings. The mean velocities that were generated warrant further validation across an extended group of patients, and the predictive value for vasospasm should be checked against the current standard of angiography. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. 24 CFR 1000.139 - What are the standards for insurance entities owned and controlled by recipients?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What are the standards for insurance entities owned and controlled by recipients? 1000.139 Section 1000.139 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY...

  19. 25 CFR 1000.229 - May a Tribe/Consortium propose a substitute for a regulation it wishes to be waived?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... regulation it wishes to be waived? 1000.229 Section 1000.229 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.229 May a Tribe...

  20. 24 CFR 1000.36 - How long must a recipient retain records regarding exceptions made to the conflict of interest...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false How long must a recipient retain records regarding exceptions made to the conflict of interest provisions? 1000.36 Section 1000.36 Housing... AMERICAN HOUSING ACTIVITIES General § 1000.36 How long must a recipient retain records regarding exceptions...

  1. Multiple recycle of REMIX fuel at VVER-1000 operation in closed fuel cycle

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Alekseev, P. N.; Bobrov, E. A., E-mail: evgeniybobrov89@rambler.ru; Chibinyaev, A. V.

    2015-12-15

    The basic features of loading the VVER-1000 core with a new variant of REMIX fuel (REgenerated MIXture of U–Pu oxides) are considered during its multiple recycle in a closed nuclear fuel cycle. The fuel composition is produced on the basis of the uranium–plutonium regenerate extracted at processing the spent nuclear fuel (SNF) from a VVER-1000, depleted uranium, and the fissionable material: {sup 235}U as a part of highly enriched uranium (HEU) from warheads superfluous for defense purposes or {sup 233}U accumulated in thorium blankets of fusion (electronuclear) neutron sources or fast reactors. Production of such a fuel assumes no usemore » of natural uranium in addition. When converting a part of the VVER-1000 reactors to the closed fuel cycle based on the REMIX technology, the consumption of natural uranium decreases considerably, and there is no substantial degradation of the isotopic composition of plutonium or change in the reactor-safety characteristics at the passage from recycle to recycle.« less

  2. 25 CFR 1000.362 - What are the consequences of a finding of imminent jeopardy in the annual trust evaluation?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What are the consequences of a finding of imminent jeopardy in the annual trust evaluation? 1000.362 Section 1000.362 Indians OFFICE OF THE ASSISTANT... Trust Evaluations § 1000.362 What are the consequences of a finding of imminent jeopardy in the annual...

  3. 25 CFR 1000.138 - How are indirect cost rates determined?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Non-BIA Annual Self-Governance Compacts and Funding Agreements Funding § 1000.138 How are... provisions of the Office of Management and Budget (OMB) Circular A-87 or other applicable OMB cost circular...

  4. 24 CFR 1000.38 - What flood insurance requirements are applicable?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What flood insurance requirements..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.38 What flood insurance requirements are applicable? Under the Flood Disaster Protection Act of 1973, as amended (42 U.S.C...

  5. 16 CFR § 1000.22 - Office of Human Resources Management.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Office of Human Resources Management. Â... ORGANIZATION AND FUNCTIONS § 1000.22 Office of Human Resources Management. The Office of Human Resources Management, which is managed by the Director of the Office, provides human resources management support to...

  6. Performance of genotype imputation for low frequency and rare variants from the 1000 genomes.

    PubMed

    Zheng, Hou-Feng; Rong, Jing-Jing; Liu, Ming; Han, Fang; Zhang, Xing-Wei; Richards, J Brent; Wang, Li

    2015-01-01

    Genotype imputation is now routinely applied in genome-wide association studies (GWAS) and meta-analyses. However, most of the imputations have been run using HapMap samples as reference, imputation of low frequency and rare variants (minor allele frequency (MAF) < 5%) are not systemically assessed. With the emergence of next-generation sequencing, large reference panels (such as the 1000 Genomes panel) are available to facilitate imputation of these variants. Therefore, in order to estimate the performance of low frequency and rare variants imputation, we imputed 153 individuals, each of whom had 3 different genotype array data including 317k, 610k and 1 million SNPs, to three different reference panels: the 1000 Genomes pilot March 2010 release (1KGpilot), the 1000 Genomes interim August 2010 release (1KGinterim), and the 1000 Genomes phase1 November 2010 and May 2011 release (1KGphase1) by using IMPUTE version 2. The differences between these three releases of the 1000 Genomes data are the sample size, ancestry diversity, number of variants and their frequency spectrum. We found that both reference panel and GWAS chip density affect the imputation of low frequency and rare variants. 1KGphase1 outperformed the other 2 panels, at higher concordance rate, higher proportion of well-imputed variants (info>0.4) and higher mean info score in each MAF bin. Similarly, 1M chip array outperformed 610K and 317K. However for very rare variants (MAF ≤ 0.3%), only 0-1% of the variants were well imputed. We conclude that the imputation of low frequency and rare variants improves with larger reference panels and higher density of genome-wide genotyping arrays. Yet, despite a large reference panel size and dense genotyping density, very rare variants remain difficult to impute.

  7. 25 CFR 1000.26 - Under what circumstances will a Tribe/Consortium be removed from the applicant pool?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Participation in Tribal Self-Governance Admission into the Applicant Pool § 1000.26 Under what circumstances... Tribe/Consortium will only be removed if it: (a) Fails to satisfy the audit criteria in § 1000.17(c); or...

  8. 24 CFR 1000.34 - What factors must be considered in making an exception to the conflict of interest provisions?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What factors must be considered in making an exception to the conflict of interest provisions? 1000.34 Section 1000.34 Housing and Urban... ACTIVITIES General § 1000.34 What factors must be considered in making an exception to the conflict of...

  9. Effects of consecutive trials and test-retest reliability of 1000-Hz tympanometry in adults.

    PubMed

    Carazo, Carla Dominguez; Sun, Xiao-Ming

    2015-04-01

    To investigate the effect of consecutive 1000-Hz tympanometry testing on admittance measures, and examine test-retest reliability. Repeated measures with eight trials of 1000-Hz Y(a) and B(a)/G(a) tympanometry, respectively, in two ears of each subject, followed by repeated 226-Hz tympanometry. Twenty-seven normal-hearing young adults. For single-peak tympanograms, peak Y(tm) and G(tm) systematically increased across trials with a mean change of 8% and 15% at Trial 8, respectively, whereas B(tm) increased marginally. For notched tympanograms, peak Y(tm) and B(tm) decreased by 23% and 162% at Trial 8, and G(tm) in two cases also decreased (10% on average). Trial 2 and 3 contributed 50% to 70% of the total changes. Test-retest differences of subsequently acquired 1000- and 226-Hz tympanograms were smaller than previously reported. Consecutive testing significantly alters middle-ear admittance in 1000-Hz tympanometry. The outcome is contingent on tympanogram pattern and admittance component: Increase of peak Y(tm) and G(tm) in single-peak tympanograms and decrease of all measures in notched tympanograms. The present results complement previous studies on our understanding of the mechanism underlying this effect: a decrease of middle-ear stiffness. The effect of repetitive tympanometry should be accounted for in research involving sequential testing.

  10. 25 CFR 1000.398 - May a Tribe/Consortium invest funds received under a self-governance agreement?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false May a Tribe/Consortium invest funds received under a self-governance agreement? 1000.398 Section 1000.398 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... invest funds received under a self-governance agreement? Yes, self-governance funds may be invested if...

  11. 49. (no plate) 1,000 poind Mercury Float Pedestal and clock ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    49. (no plate) 1,000 poind Mercury Float Pedestal and clock case sheet no. 1 of 4 drawing # 5765. Approved 2-3-1916. - Block Island Southeast Light, Spring Street & Mohegan Trail at Mohegan Bluffs, New Shoreham, Washington County, RI

  12. Comparison of multi-proxy data with past1000 model output over the Terminal Classic Period (800-1000 A.D.) on the Yucatan Peninsula.

    NASA Astrophysics Data System (ADS)

    Van Pelt, S.; Kohfeld, K. E.; Allen, D. M.

    2015-12-01

    The decline of the Mayan Civilization is thought to be caused by a series of droughts that affected the Yucatan Peninsula during the Terminal Classic Period (T.C.P.) 800-1000 AD. The goals of this study are two-fold: (a) to compare paleo-model simulations of the past 1000 years with a compilation of multiple proxies of changes in moisture conditions for the Yucatan Peninsula during the T.C.P. and (b) to use this comparison to inform the modeling of groundwater recharge in this region, with a focus on generating the daily climate data series needed as input to a groundwater recharge model. To achieve the first objective, we compiled a dataset of 5 proxies from seven locations across the Yucatan Peninsula, to be compared with temperature and precipitation output from the Community Climate System Model Version 4 (CCSM4), which is part of the Coupled Model Intercomparison Project Phase 5 (CMIP5) past1000 experiment. The proxy dataset includes oxygen isotopes from speleothems and gastropod/ostrocod shells (11 records); and sediment density, mineralogy, and magnetic susceptibility records from lake sediment cores (3 records). The proxy dataset is supplemented by a compilation of reconstructed temperatures using pollen and tree ring records for North America (archived in the PAGES2k global network data). Our preliminary analysis suggests that many of these datasets show evidence of drier and warmer climate on the Yucatan Peninsula around the T.C.P. when compared to modern conditions, although the amplitude and timing of individual warming and drying events varies between sites. This comparison with modeled output will ultimately be used to inform backward shift factors that will be input to a stochastic weather generator. These shift factors will be based on monthly changes in temperature and precipitation and applied to a modern daily climate time series for the Yucatan Peninsula to produce a daily climate time series for the T.C.P.

  13. Addressing the characterisation challenge to understand catalysis in MOFs: the case of nanoscale Cu supported in NU-1000.

    PubMed

    Platero-Prats, Ana E; Li, Zhanyong; Gallington, Leighanne C; Peters, Aaron W; Hupp, Joseph T; Farha, Omar K; Chapman, Karena W

    2017-09-01

    We explore the dynamic structure and reactivity of Cu species supported on NU-1000. By combining pair distribution function (PDF) analysis and difference envelope density (DED) analysis of in situ synchrotron-based X-ray scattering data, we simultaneously probe the local structure of supported Cu-species, their distribution within NU-1000 and distortions of the NU-1000 lattice under conditions relevant to catalysis and catalyst activation. These analyses show that atomic layer deposition (ALD) of Cu in NU-1000 (Cu-AIM) leads to the formation of Cu-oxo clusters within the small pores that connect the triangular and hexagonal channels. Exposure of Cu-AIM to a reducing atmosphere at 200 °C produces metallic Cu 0 of two distinct particle sizes: ∼4 nm nanoparticles and small sub-nanometer clusters. The size of these nanoparticles appears to be constrained by NU-1000 pore dimensions, with evidence of the sub-nanometer clusters being bound within the triangular channels flanked by pyrene rings. This supported Cu 0 -NU-1000 system is catalytically active for gas-phase ethylene hydrogenation. Exposure of the catalyst to oxidative atmosphere re-oxidises the Cu species to a Cu 2 O cuprite phase. The dynamic restructuring of the system in different chemical environments underscores the importance of probing these systems in situ.

  14. 25 CFR 1000.41 - What types of grants are available?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... subpart B of this part; (b) Planning grants may be available to Tribes/Consortia requiring advance funding to meet the planning phase requirement of the Act; and (c) Financial assistance may be available to... EDUCATION ACT Section 402(d) Planning and Negotiation Grants Purpose and Types of Grants § 1000.41 What...

  15. 15. GENERAL EASTERN VIEW OF LINDE 1000 TONS PER DAY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. GENERAL EASTERN VIEW OF LINDE 1000 TONS PER DAY HIGH PURITY OXYGEN MAKING PLANT SHOWING TWIN OXYGEN FRACTIONATING TOWER (ON RIGHT), VERMICULITE STORAGE TOWERS (ON LEFT FOREGROUND), AND AN ARGON FRACTIONATING TOWER (BEHIND VERMICULITE STORAGE TOWER). - U.S. Steel Duquesne Works, Fuel & Utilities Plant, Along Monongahela River, Duquesne, Allegheny County, PA

  16. 25 CFR 1000.73 - Once a Tribe/Consortium has been awarded a grant, may the Tribe/Consortium obtain information...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false Once a Tribe/Consortium has been awarded a grant, may the Tribe/Consortium obtain information from a non-BIA bureau? 1000.73 Section 1000.73 Indians OFFICE OF THE... § 1000.73 Once a Tribe/Consortium has been awarded a grant, may the Tribe/Consortium obtain information...

  17. AP1000{sup R} design robustness against extreme external events - Seismic, flooding, and aircraft crash

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pfister, A.; Goossen, C.; Coogler, K.

    2012-07-01

    Both the International Atomic Energy Agency (IAEA) and the U.S. Nuclear Regulatory Commission (NRC) require existing and new nuclear power plants to conduct plant assessments to demonstrate the unit's ability to withstand external hazards. The events that occurred at the Fukushima-Dai-ichi nuclear power station demonstrated the importance of designing a nuclear power plant with the ability to protect the plant against extreme external hazards. The innovative design of the AP1000{sup R} nuclear power plant provides unparalleled protection against catastrophic external events which can lead to extensive infrastructure damage and place the plant in an extended abnormal situation. The AP1000 plantmore » is an 1100-MWe pressurized water reactor with passive safety features and extensive plant simplifications that enhance construction, operation, maintenance and safety. The plant's compact safety related footprint and protection provided by its robust nuclear island structures prevent significant damage to systems, structures, and components required to safely shutdown the plant and maintain core and spent fuel pool cooling and containment integrity following extreme external events. The AP1000 nuclear power plant has been extensively analyzed and reviewed to demonstrate that it's nuclear island design and plant layout provide protection against both design basis and extreme beyond design basis external hazards such as extreme seismic events, external flooding that exceeds the maximum probable flood limit, and malicious aircraft impact. The AP1000 nuclear power plant uses fail safe passive features to mitigate design basis accidents. The passive safety systems are designed to function without safety-grade support systems (such as AC power, component cooling water, service water, compressed air or HVAC). The plant has been designed to protect systems, structures, and components critical to placing the reactor in a safe shutdown condition within the steel containment

  18. 24 CFR 1000.116 - What should HUD do before declining a proposal to provide assistance to non low-income Indian...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... a proposal to provide assistance to non low-income Indian families or a model housing activity? 1000.116 Section 1000.116 Housing and Urban Development Regulations Relating to Housing and Urban... URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES Affordable Housing Activities § 1000.116 What...

  19. Production Facility Prototype Blower 1000 Hour Test Results

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Woloshun, Keith Albert; Dale, Gregory E.; Romero, Frank Patrick

    2016-10-18

    The roots blower in use at ANL for in-beam experiments and also at LANL for flow tests was sized for 12 mm diameter disks and significantly less beam heating. Currently, the disks are 29 mm in diameter, with a 12 mm FWHM Gaussian beam spot at 42 MeV and 2.86 μA on each side of the target, 5.72 μA total. The target design itself is reported elsewhere. With the increased beam heating, the helium flow requirement increased so that a larger blower was needed for a mass flow rate of 400 g/s at 2.76 MPa (400 psig). An Aerzen GMmore » 12.4 blower was selected, and is now installed at the LANL facility for target and component flow testing. Two extended tests of >1000 hr operation have been completed. Those results and discussion thereof are reported herein. Also included in Appendix A is the detailed description of the blower and its installation, while Appendix B documents the pressure vessel design analysis. The blower has been operated for 1000 hours as a preliminary investigation of long-term performance, operation and possible maintenance issues. The blower performed well, with no significant change in blower head or mass flow rate developed under the operating conditions. Upon inspection, some oil had leaked out of the shaft seal of the blower. The shaft seal and bearing race have been replaced. Test results and conclusions are in Appendix B.« less

  20. 25 CFR 1000.13 - What is a “nonsignatory Tribe”?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Selection of Additional Tribes for Participation in Tribal Self-Governance Purpose and Definitions § 1000.13 What is a “nonsignatory Tribe”? (a) A nonsignatory Tribe is a Tribe that either: (1) Does not meet the... its behalf. (b) A non-signatory tribe under paragraph (a)(1) of this section: (1) May not sign the...

  1. 25 CFR 1000.13 - What is a “nonsignatory Tribe”?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Selection of Additional Tribes for Participation in Tribal Self-Governance Purpose and Definitions § 1000.13 What is a “nonsignatory Tribe”? (a) A nonsignatory Tribe is a Tribe that either: (1) Does not meet the... its behalf. (b) A non-signatory tribe under paragraph (a)(1) of this section: (1) May not sign the...

  2. 25 CFR 1000.13 - What is a “nonsignatory Tribe”?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Selection of Additional Tribes for Participation in Tribal Self-Governance Purpose and Definitions § 1000.13 What is a “nonsignatory Tribe”? (a) A nonsignatory Tribe is a Tribe that either: (1) Does not meet the... its behalf. (b) A non-signatory tribe under paragraph (a)(1) of this section: (1) May not sign the...

  3. 25 CFR 1000.13 - What is a “nonsignatory Tribe”?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Selection of Additional Tribes for Participation in Tribal Self-Governance Purpose and Definitions § 1000.13 What is a “nonsignatory Tribe”? (a) A nonsignatory Tribe is a Tribe that either: (1) Does not meet the... its behalf. (b) A non-signatory tribe under paragraph (a)(1) of this section: (1) May not sign the...

  4. 1,000 Days: Mobilizing Investments for Healthier, More Prosperous Futures

    ERIC Educational Resources Information Center

    Sullivan, Lucy Martinez; Sakayan, Mannik; Cernak, Kimberly

    2018-01-01

    Good nutrition during the 1,000-day window between pregnancy and 2 years old can give children the opportunity to reach their full potential. Conversely, malnutrition early in life can cause irreversible damage to a child's brain development and physical growth, leading to a lifetime of poor health and lost potential. Each year, malnutrition costs…

  5. High-Temperature (1000 F) Magnetic Thrust Bearing Test Rig Completed and Operational

    NASA Technical Reports Server (NTRS)

    Montague, Gerald T.

    2005-01-01

    Large axial loads are induced on the rolling element bearings of a gas turbine. To extend bearing life, designers use pneumatic balance pistons to reduce the axial load on the bearings. A magnetic thrust bearing could replace the balance pistons to further reduce the axial load. To investigate this option, the U.S. Army Research Laboratory, the NASA Glenn Research Center, and Texas A&M University designed and fabricated a 7-in.- diameter magnetic thrust bearing to operate at 1000 F and 30,000 rpm, with a 1000-lb load capacity. This research was funded through a NASA Space Technology Transfer Act with Allison Advance Development Company under the Ultra-Efficient Engine Technology (UEET) Intelligent Propulsion Systems Foundation Technology project.

  6. Methane Oxidation to Methanol Catalyzed by Cu-Oxo Clusters Stabilized in NU-1000 Metal-Organic Framework.

    PubMed

    Ikuno, Takaaki; Zheng, Jian; Vjunov, Aleksei; Sanchez-Sanchez, Maricruz; Ortuño, Manuel A; Pahls, Dale R; Fulton, John L; Camaioni, Donald M; Li, Zhanyong; Ray, Debmalya; Mehdi, B Layla; Browning, Nigel D; Farha, Omar K; Hupp, Joseph T; Cramer, Christopher J; Gagliardi, Laura; Lercher, Johannes A

    2017-08-02

    Copper oxide clusters synthesized via atomic layer deposition on the nodes of the metal-organic framework (MOF) NU-1000 are active for oxidation of methane to methanol under mild reaction conditions. Analysis of chemical reactivity, in situ X-ray absorption spectroscopy, and density functional theory calculations are used to determine structure/activity relations in the Cu-NU-1000 catalytic system. The Cu-loaded MOF contained Cu-oxo clusters of a few Cu atoms. The Cu was present under ambient conditions as a mixture of ∼15% Cu + and ∼85% Cu 2+ . The oxidation of methane on Cu-NU-1000 was accompanied by the reduction of 9% of the Cu in the catalyst from Cu 2+ to Cu + . The products, methanol, dimethyl ether, and CO 2 , were desorbed with the passage of 10% water/He at 135 °C, giving a carbon selectivity for methane to methanol of 45-60%. Cu oxo clusters stabilized in NU-1000 provide an active, first generation MOF-based, selective methane oxidation catalyst.

  7. 25 CFR 1000.461 - What must a Tribe/Consortium do if an organizational conflict of interest arises under an AFA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... conflict of interest arises under an AFA? 1000.461 Section 1000.461 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Conflicts of Interest § 1000.461...

  8. Low cycle fatigue behavior of polycrystalline NiAl at 300 and 1000 K

    NASA Technical Reports Server (NTRS)

    Lerch, Bradley A.; Noebe, Ronald D.

    1993-01-01

    The low cycle fatigue behavior of polycrystalline NiAl was determined at 300 and 1000 K - temperatures below and above the brittle- to-ductile transition temperature (BDTT). Fully reversed, plastic strain-controlled fatigue tests were conducted on two differently fabricated alloy samples: hot isostatically pressed (HIP'ed) prealloyed powder and hot extruded castings. HIP'ed powder (HP) samples were tested only at 1000 K, whereas the more ductile cast-and-extruded (C+E) NiAl samples were tested at both 1000 and 300 K. Plastic strain ranges of 0.06 to 0.2 percent were used. The C+E NiAl cyclically hardened until fracture, reaching stress levels approximately 60 percent greater than the ultimate tensile strength of the alloy. Compared on a strain basis, NiAl had a much longer fatigue life than other B2 ordered compounds in which fracture initiated at processing-related defects. These defects controlled fatigue life at 300 K, with fracture occurring rapidly once a critical stress level was reached. At 1000 K, above the BDTT, both the C+E and HP samples cyclically softened during most of the fatigue tests in air and were insensitive to processing defects. The processing method did not have a major effect on fatigue life; the lives of the HP samples were about a factor of three shorter than the C+E NiAl, but this was attributed to the lower stress response of the C+E material. The C+E NiAl underwent dynamic grain growth, whereas the HP material maintained a constant grain size during testing. In both materials, fatigue life was controlled by intergranular cavitation and creep processes, which led to fatigue crack growth that was primarily intergranular in nature. Final fracture by overload was transgranular in nature. Also, HP samples tested in vacuum had a life three times longer than their counterparts tested in air and, in contrast to those tested in air, hardened continuously over half of the sample life, thereby indicating an environmentally assisted fatigue damage

  9. 24 CFR 1000.436 - How will HUD monitor the use of funds guaranteed under this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false How will HUD monitor the use of funds guaranteed under this subpart? 1000.436 Section 1000.436 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN HOUSING, DEPARTMENT OF HOUSING AND URBAN...

  10. 25 CFR 1000.181 - How does the Tribe/Consortium initiate the negotiation of a successor AFA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false How does the Tribe/Consortium initiate the negotiation of a successor AFA? 1000.181 Section 1000.181 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATIO...

  11. Addressing the characterisation challenge to understand catalysis in MOFs: the case of nanoscale Cu supported in NU-1000

    DOE PAGES

    Platero-Prats, Ana E.; Li, Zhanyong; Gallington, Leighanne C.; ...

    2017-04-03

    Here, we explore the dynamic structure and reactivity of Cu species supported on NU-1000. By combining pair distribution function (PDF) analysis and difference envelope density (DED) analysis ofin situsynchrotron-based X-ray scattering data, we simultaneously probe the local structure of supported Cu-species, their distribution within NU-1000 and distortions of the NU-1000 lattice under conditions relevant to catalysis and catalyst activation. Our analyses show that atomic layer deposition (ALD) of Cu in NU-1000 (Cu-AIM) leads to the formation of Cu-oxo clusters within the small pores that connect the triangular and hexagonal channels. Exposure of Cu-AIM to a reducing atmosphere at 200 °Cmore » produces metallic Cu 0of two distinct particle sizes: ~4 nm nanoparticles and small sub-nanometer clusters. The size of these nanoparticles appears to be constrained by NU-1000 pore dimensions, with evidence of the sub-nanometer clusters being bound within the triangular channels flanked by pyrene rings. This supported Cu 0–NU-1000 system is catalytically active for gas-phase ethylene hydrogenation. Exposure of the catalyst to oxidative atmosphere re-oxidises the Cu species to a Cu 2O cuprite phase. The dynamic restructuring of the system in different chemical environments underscores the importance of probing these systemsin situ.« less

  12. 25 CFR 1000.396 - Does a Tribe/Consortium have additional ongoing requirements to maintain minimum standards for...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... requirements to maintain minimum standards for Tribe/Consortium management systems? 1000.396 Section 1000.396... AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT... minimum standards for Tribe/Consortium management systems? Yes, the Tribe/Consortium must maintain...

  13. Propane in nitrogen, 1000 μmol/mol

    NASA Astrophysics Data System (ADS)

    Konopelko, L. A.; Kustikov, Y. A.; Kolobova, A. V.; Pankratov, V. V.; Pankov, A. A.; Efremova, O. V.; Rozhnov, M. S.; Melnyk, D. M.; Petryshyn, P. V.; Levbarg, O. S.; Kisel, S. P.; Shpilnyi, S. A.; Yakubov, S. Ye; Bakovec, N. V.; Mironchik, A. M.; Aleksandrov, V. V.

    2017-01-01

    This article presents the report on the COOMET key comparison COOMET.QM-K111, which is linking to the appropriate CCQM comparison—CCQM-K111 'Propane in nitrogen 1000 μmol/mol'. CCQM-K111 was carried out in 2014-2016 and it was one of a series of key comparisons in the gas analysis area assessing core competences. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  14. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in 1000 patients with perforated appendiceal epithelial tumours.

    PubMed

    Ansari, N; Chandrakumaran, K; Dayal, S; Mohamed, F; Cecil, T D; Moran, B J

    2016-07-01

    To report early and long term outcomes following cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in 1000 patients with perforated appendiceal epithelial tumours, predominantly with pseudomyxoma peritonei (PMP). Retrospective analysis of a prospective database of 1000 consecutive patients undergoing CRS and HIPEC for perforated appendiceal tumours between 1994 and 2014 in a UK National Peritoneal Malignancy unit. Overall 1000/1444 (69.2%) patients treated for peritoneal malignancy had appendiceal primary tumours. Of these 738/1000 (73.8%) underwent complete cytoreductive surgery (CCRS), 242 (24.2%) had maximal tumour debulking (MTD) and 20 (2%) had laparotomy and biopsies only. Treatment related 30-day mortality was 0.8% in CCRS and 1.7% in MTD group with major postoperative morbidity rates of 15.2% (CCRS) and 14.5% (MTD). Five- and 10-year overall survival was 87.4% and 70.3% in the 738 patients who had CCRS compared with 39.2% and 8.1% respectively in the MTD group. On multivariate analysis, significant predictors of reduced overall survival were male gender (p = 0.022), elevated CEA (p = 0.001), elevated CA125 (p = 0.001) and high tumour grade or adenocarcinoma (p = 0.001). Perforated epithelial appendiceal tumours are rare, though may be increasing in incidence and can present unexpectedly at elective or emergency abdominal surgery, often with PMP. CRS and HIPEC results in good long term outcomes in most patients. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. 25 CFR 1000.72 - Will OSG notify Tribes/Consortia and affected non-BIA bureaus of the results of the selection...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... bureaus of the results of the selection process? 1000.72 Section 1000.72 Indians OFFICE OF THE ASSISTANT...-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Other Financial Assistance for Planning and Negotiation Grants for Non-BIA Programs Eligibility and Application Process § 1000.72 Will OSG...

  16. 25 CFR 1000.72 - Will OSG notify Tribes/Consortia and affected non-BIA bureaus of the results of the selection...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... bureaus of the results of the selection process? 1000.72 Section 1000.72 Indians OFFICE OF THE ASSISTANT...-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Other Financial Assistance for Planning and Negotiation Grants for Non-BIA Programs Eligibility and Application Process § 1000.72 Will OSG...

  17. 25 CFR 1000.72 - Will OSG notify Tribes/Consortia and affected non-BIA bureaus of the results of the selection...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... bureaus of the results of the selection process? 1000.72 Section 1000.72 Indians OFFICE OF THE ASSISTANT...-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Other Financial Assistance for Planning and Negotiation Grants for Non-BIA Programs Eligibility and Application Process § 1000.72 Will OSG...

  18. 25 CFR 1000.72 - Will OSG notify Tribes/Consortia and affected non-BIA bureaus of the results of the selection...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... bureaus of the results of the selection process? 1000.72 Section 1000.72 Indians OFFICE OF THE ASSISTANT...-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Other Financial Assistance for Planning and Negotiation Grants for Non-BIA Programs Eligibility and Application Process § 1000.72 Will OSG...

  19. Predicted structure of MIF/CD74 and RTL1000/CD74 complexes.

    PubMed

    Meza-Romero, Roberto; Benedek, Gil; Leng, Lin; Bucala, Richard; Vandenbark, Arthur A

    2016-04-01

    Macrophage migration inhibitory factor (MIF) is a key cytokine in autoimmune and inflammatory diseases that attracts and then retains activated immune cells from the periphery to the tissues. MIF exists as a homotrimer and its effects are mediated through its primary receptor, CD74 (the class II invariant chain that exhibits a highly structured trimerization domain), present on class II expressing cells. Although a number of binding residues have been identified between MIF and CD74 trimers, their spatial orientation has not been established. Using a docking program in silico, we have modeled binding interactions between CD74 and MIF as well as CD74 and a competitive MIF inhibitor, RTL1000, a partial MHC class II construct that is currently in clinical trials for multiple sclerosis. These analyses revealed 3 binding sites on the MIF trimer that each were predicted to bind one CD74 trimer through interactions with two distinct 5 amino acid determinants. Surprisingly, predicted binding of one CD74 trimer to a single RTL1000 antagonist utilized the same two 5 residue determinants, providing strong suggestive evidence in support of the MIF binding regions on CD74. Taken together, our structural modeling predicts a new MIF(CD74)3 dodecamer that may provide the basis for increased MIF potency and the requirement for ~3-fold excess RTL1000 to achieve full antagonism.

  20. 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

    PubMed Central

    Gorski, Mathias; van der Most, Peter J.; Teumer, Alexander; Chu, Audrey Y.; Li, Man; Mijatovic, Vladan; Nolte, Ilja M.; Cocca, Massimiliano; Taliun, Daniel; Gomez, Felicia; Li, Yong; Tayo, Bamidele; Tin, Adrienne; Feitosa, Mary F.; Aspelund, Thor; Attia, John; Biffar, Reiner; Bochud, Murielle; Boerwinkle, Eric; Borecki, Ingrid; Bottinger, Erwin P.; Chen, Ming-Huei; Chouraki, Vincent; Ciullo, Marina; Coresh, Josef; Cornelis, Marilyn C.; Curhan, Gary C.; d’Adamo, Adamo Pio; Dehghan, Abbas; Dengler, Laura; Ding, Jingzhong; Eiriksdottir, Gudny; Endlich, Karlhans; Enroth, Stefan; Esko, Tõnu; Franco, Oscar H.; Gasparini, Paolo; Gieger, Christian; Girotto, Giorgia; Gottesman, Omri; Gudnason, Vilmundur; Gyllensten, Ulf; Hancock, Stephen J.; Harris, Tamara B.; Helmer, Catherine; Höllerer, Simon; Hofer, Edith; Hofman, Albert; Holliday, Elizabeth G.; Homuth, Georg; Hu, Frank B.; Huth, Cornelia; Hutri-Kähönen, Nina; Hwang, Shih-Jen; Imboden, Medea; Johansson, Åsa; Kähönen, Mika; König, Wolfgang; Kramer, Holly; Krämer, Bernhard K.; Kumar, Ashish; Kutalik, Zoltan; Lambert, Jean-Charles; Launer, Lenore J.; Lehtimäki, Terho; de Borst, Martin; Navis, Gerjan; Swertz, Morris; Liu, Yongmei; Lohman, Kurt; Loos, Ruth J. F.; Lu, Yingchang; Lyytikäinen, Leo-Pekka; McEvoy, Mark A.; Meisinger, Christa; Meitinger, Thomas; Metspalu, Andres; Metzger, Marie; Mihailov, Evelin; Mitchell, Paul; Nauck, Matthias; Oldehinkel, Albertine J.; Olden, Matthias; WJH Penninx, Brenda; Pistis, Giorgio; Pramstaller, Peter P.; Probst-Hensch, Nicole; Raitakari, Olli T.; Rettig, Rainer; Ridker, Paul M.; Rivadeneira, Fernando; Robino, Antonietta; Rosas, Sylvia E.; Ruderfer, Douglas; Ruggiero, Daniela; Saba, Yasaman; Sala, Cinzia; Schmidt, Helena; Schmidt, Reinhold; Scott, Rodney J.; Sedaghat, Sanaz; Smith, Albert V.; Sorice, Rossella; Stengel, Benedicte; Stracke, Sylvia; Strauch, Konstantin; Toniolo, Daniela; Uitterlinden, Andre G.; Ulivi, Sheila; Viikari, Jorma S.; Völker, Uwe; Vollenweider, Peter; Völzke, Henry; Vuckovic, Dragana; Waldenberger, Melanie; Jin Wang, Jie; Yang, Qiong; Chasman, Daniel I.; Tromp, Gerard; Snieder, Harold; Heid, Iris M.; Fox, Caroline S.; Köttgen, Anna; Pattaro, Cristian; Böger, Carsten A.; Fuchsberger, Christian

    2017-01-01

    HapMap imputed genome-wide association studies (GWAS) have revealed >50 loci at which common variants with minor allele frequency >5% are associated with kidney function. GWAS using more complete reference sets for imputation, such as those from The 1000 Genomes project, promise to identify novel loci that have been missed by previous efforts. To investigate the value of such a more complete variant catalog, we conducted a GWAS meta-analysis of kidney function based on the estimated glomerular filtration rate (eGFR) in 110,517 European ancestry participants using 1000 Genomes imputed data. We identified 10 novel loci with p-value < 5 × 10−8 previously missed by HapMap-based GWAS. Six of these loci (HOXD8, ARL15, PIK3R1, EYA4, ASTN2, and EPB41L3) are tagged by common SNPs unique to the 1000 Genomes reference panel. Using pathway analysis, we identified 39 significant (FDR < 0.05) genes and 127 significantly (FDR < 0.05) enriched gene sets, which were missed by our previous analyses. Among those, the 10 identified novel genes are part of pathways of kidney development, carbohydrate metabolism, cardiac septum development and glucose metabolism. These results highlight the utility of re-imputing from denser reference panels, until whole-genome sequencing becomes feasible in large samples. PMID:28452372

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